Search of human proteins with 5453543

Search of human proteins with 5453543

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5453543 aldo-keto reductase family 1, member C1 [Homo
sapiens]
         (323 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5453543 aldo-keto reductase family 1, member C1 [Homo sapiens]     659   0.0  
gi|45446745 aldo-keto reductase family 1, member C2 [Homo sapiens]    644   0.0  
gi|4503285 aldo-keto reductase family 1, member C2 [Homo sapiens]     644   0.0  
gi|24497583 aldo-keto reductase family 1, member C3 [Homo sapiens]    585   e-167
gi|24497585 aldo-keto reductase family 1, member C4 [Homo sapiens]    558   e-159
gi|5174695 aldo-keto reductase family 1, member D1 [Homo sapiens]     397   e-111
gi|4502049 aldo-keto reductase family 1, member B1 [Homo sapiens]     322   4e-88
gi|223468663 aldo-keto reductase family 1, member B10 [Homo sapi...   303   1e-82
gi|122937516 aldo-keto reductase family 1, member B10-like [Homo...   292   3e-79
gi|93277124 aldo-keto reductase family 1, member C-like 2 [Homo ...   272   3e-73
gi|24497577 aldo-keto reductase family 1, member A1 [Homo sapiens]    271   6e-73
gi|5174391 aldo-keto reductase family 1, member A1 [Homo sapiens]     271   6e-73
gi|207028673 hypothetical protein LOC100134257 [Homo sapiens]         243   2e-64
gi|223718708 aflatoxin B1 aldehyde reductase 3 isoform 2 [Homo s...    57   2e-08
gi|223718702 aflatoxin B1 aldehyde reductase 3 isoform 1 [Homo s...    57   2e-08
gi|41152114 aldo-keto reductase family 7, member A3 [Homo sapiens]     53   4e-07
gi|41327764 aldo-keto reductase family 7, member A2 [Homo sapiens]     47   2e-05
gi|27436964 potassium voltage-gated channel, shaker-related subf...    39   0.005
gi|27436962 potassium voltage-gated channel, shaker-related subf...    39   0.005
gi|27436966 potassium voltage-gated channel, shaker-related subf...    39   0.005
gi|4504825 potassium voltage-gated channel, shaker-related subfa...    34   0.15 
gi|27436969 potassium voltage-gated channel, shaker-related subf...    34   0.15 
gi|27436971 potassium voltage-gated channel, shaker-related subf...    31   1.3  
gi|4503503 eukaryotic translation initiation factor 2B, subunit ...    31   1.7  
gi|193211614 NAD(P) dependent steroid dehydrogenase-like [Homo s...    30   2.9  
gi|8393516 NAD(P) dependent steroid dehydrogenase-like [Homo sap...    30   2.9  

>gi|5453543 aldo-keto reductase family 1, member C1 [Homo sapiens]
          Length = 323

 Score =  659 bits (1700), Expect = 0.0
 Identities = 323/323 (100%), Positives = 323/323 (100%)

Query: 1   MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQ 60
           MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQ
Sbjct: 1   MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQ 60

Query: 61  VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
           VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120

Query: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
           SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180

Query: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
           GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240

Query: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300
           LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300

Query: 301 RNVRYLTLDIFAGPPNYPFSDEY 323
           RNVRYLTLDIFAGPPNYPFSDEY
Sbjct: 301 RNVRYLTLDIFAGPPNYPFSDEY 323


>gi|45446745 aldo-keto reductase family 1, member C2 [Homo sapiens]
          Length = 323

 Score =  644 bits (1662), Expect = 0.0
 Identities = 316/323 (97%), Positives = 318/323 (98%)

Query: 1   MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQ 60
           MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEA KLAIEAGF HIDSAH+YNNEEQ
Sbjct: 1   MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQ 60

Query: 61  VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
           VGLAIRSKIADGSVKREDIFYTSKLW NSHRPELVRPALERSLKNLQLDYVDLYLIHFPV
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120

Query: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
           SVKPGEEVIPKDENGKILFDTVDLCATWEA+EKCKDAGLAKSIGVSNFN R LEMILNKP
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180

Query: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
           GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240

Query: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300
           LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300

Query: 301 RNVRYLTLDIFAGPPNYPFSDEY 323
           RNVRYLTLDIFAGPPNYPFSDEY
Sbjct: 301 RNVRYLTLDIFAGPPNYPFSDEY 323


>gi|4503285 aldo-keto reductase family 1, member C2 [Homo sapiens]
          Length = 323

 Score =  644 bits (1662), Expect = 0.0
 Identities = 316/323 (97%), Positives = 318/323 (98%)

Query: 1   MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQ 60
           MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEA KLAIEAGF HIDSAH+YNNEEQ
Sbjct: 1   MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQ 60

Query: 61  VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
           VGLAIRSKIADGSVKREDIFYTSKLW NSHRPELVRPALERSLKNLQLDYVDLYLIHFPV
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120

Query: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
           SVKPGEEVIPKDENGKILFDTVDLCATWEA+EKCKDAGLAKSIGVSNFN R LEMILNKP
Sbjct: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKP 180

Query: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
           GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV
Sbjct: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240

Query: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300
           LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300

Query: 301 RNVRYLTLDIFAGPPNYPFSDEY 323
           RNVRYLTLDIFAGPPNYPFSDEY
Sbjct: 301 RNVRYLTLDIFAGPPNYPFSDEY 323


>gi|24497583 aldo-keto reductase family 1, member C3 [Homo sapiens]
          Length = 323

 Score =  585 bits (1508), Expect = e-167
 Identities = 284/323 (87%), Positives = 300/323 (92%)

Query: 1   MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQ 60
           MDSK+QCVKLNDGHFMPVLGFGTYAP EVP+SKALE TKLAIEAGFRHIDSAHLYNNEEQ
Sbjct: 1   MDSKHQCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQ 60

Query: 61  VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
           VGLAIRSKIADGSVKREDIFYTSKLW   HRPELVRPALE SLK  QLDYVDLYLIH P+
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM 120

Query: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
           S+KPGEE+ P DENGK++FD VDLC TWEA+EKCKDAGLAKSIGVSNFNRRQLEMILNKP
Sbjct: 121 SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180

Query: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
           GLKYKPVCNQVECHPYFN+ KLLDFCKSKDIVLVAYSALGS R++ WVDPNSPVLLEDPV
Sbjct: 181 GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV 240

Query: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300
           LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLT+E+MKAIDGL+
Sbjct: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLD 300

Query: 301 RNVRYLTLDIFAGPPNYPFSDEY 323
           RN+ Y   D FA  PNYP+SDEY
Sbjct: 301 RNLHYFNSDSFASHPNYPYSDEY 323


>gi|24497585 aldo-keto reductase family 1, member C4 [Homo sapiens]
          Length = 323

 Score =  558 bits (1438), Expect = e-159
 Identities = 267/323 (82%), Positives = 296/323 (91%)

Query: 1   MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQ 60
           MD KYQ V+LNDGHFMPVLGFGTYAP EVP+++A+E TKLAIEAGFRHIDSA+LYNNEEQ
Sbjct: 1   MDPKYQRVELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQ 60

Query: 61  VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
           VGLAIRSKIADGSVKREDIFYTSKLWC   +P++V+PALE SLK LQLDYVDLYL+HFP+
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPM 120

Query: 121 SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP 180
           ++KPGE  +PKDENGK++FDTVDL ATWE +EKCKDAGLAKSIGVSNFN RQLEMILNKP
Sbjct: 121 ALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKP 180

Query: 181 GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV 240
           GLKYKPVCNQVECHPY NQ KLLDFCKSKDIVLVA+SALG+ R + WVDPNSPVLLEDPV
Sbjct: 181 GLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPV 240

Query: 241 LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN 300
           LCALAKKHK+TPALIALRYQLQRGVVVLAKSYNEQRIR+N+QVFEFQLTSE+MK +DGLN
Sbjct: 241 LCALAKKHKQTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLN 300

Query: 301 RNVRYLTLDIFAGPPNYPFSDEY 323
           RN RY+ +D     P+YPFSDEY
Sbjct: 301 RNYRYVVMDFLMDHPDYPFSDEY 323


>gi|5174695 aldo-keto reductase family 1, member D1 [Homo sapiens]
          Length = 326

 Score =  397 bits (1021), Expect = e-111
 Identities = 186/317 (58%), Positives = 244/317 (76%), Gaps = 1/317 (0%)

Query: 8   VKLNDGHFMPVLGFGTYA-PAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIR 66
           + L+DG+ +P++G GTY+ P   PK     + K+AI+ G+RHID A++Y NE +VG AIR
Sbjct: 10  IPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIR 69

Query: 67  SKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGE 126
            KIA+G V+REDIFY  KLW  +H PE+VRP LER+L+ LQLDYVDLY+I  P++ KPG+
Sbjct: 70  EKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGD 129

Query: 127 EVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKP 186
           E+ P+DENGK L+   +LCATWEA+E CKDAGL KS+GVSNFNRRQLE+ILNKPGLK+KP
Sbjct: 130 EIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKP 189

Query: 187 VCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAK 246
           V NQVECHPYF Q KLL FC+  DIV+ AYS LG+ R   WV+ +SP LL+D +L +L K
Sbjct: 190 VSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALLNSLGK 249

Query: 247 KHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYL 306
           ++ +T A I LR+ +QRGVVV+ KS+N +RI++N Q+F+F LT EEMK I+ LN+NVR++
Sbjct: 250 RYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEEEMKDIEALNKNVRFV 309

Query: 307 TLDIFAGPPNYPFSDEY 323
            L ++   P YPF DEY
Sbjct: 310 ELLMWRDHPEYPFHDEY 326


>gi|4502049 aldo-keto reductase family 1, member B1 [Homo sapiens]
          Length = 316

 Score =  322 bits (824), Expect = 4e-88
 Identities = 153/314 (48%), Positives = 215/314 (68%), Gaps = 4/314 (1%)

Query: 10  LNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKI 69
           LN+G  MP+LG GT+   + P  +  EA K+AI+ G+RHID AH+Y NE +VG+AI+ K+
Sbjct: 7   LNNGAKMPILGLGTW---KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKL 63

Query: 70  ADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVI 129
            +  VKRE++F  SKLWC  H   LV+ A +++L +L+LDY+DLYLIH+P   KPG+E  
Sbjct: 64  REQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFF 123

Query: 130 PKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCN 189
           P DE+G ++    ++  TW A+E+  D GL K+IG+SNFN  Q+EMILNKPGLKYKP  N
Sbjct: 124 PLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVN 183

Query: 190 QVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHK 249
           Q+ECHPY  Q KL+ +C+SK IV+ AYS LGS  + PW  P  P LLEDP + A+A KH 
Sbjct: 184 QIECHPYLTQEKLIQYCQSKGIVVTAYSPLGS-PDRPWAKPEDPSLLEDPRIKAIAAKHN 242

Query: 250 RTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLD 309
           +T A + +R+ +QR +VV+ KS   +RI +N +VF+F+L+S++M  +   NRN R   L 
Sbjct: 243 KTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALL 302

Query: 310 IFAGPPNYPFSDEY 323
                 +YPF +E+
Sbjct: 303 SCTSHKDYPFHEEF 316


>gi|223468663 aldo-keto reductase family 1, member B10 [Homo
           sapiens]
          Length = 316

 Score =  303 bits (777), Expect = 1e-82
 Identities = 152/316 (48%), Positives = 209/316 (66%), Gaps = 4/316 (1%)

Query: 8   VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
           V+L+    MP++G GT+   + P  K  EA K+AI+AG+RHID A++Y NE +VG AI+ 
Sbjct: 5   VELSTKAKMPIVGLGTW---KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQE 61

Query: 68  KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
           KI + +VKRED+F  SKLW       LVR A E++LK+L+L Y+D+YLIH+P   K G++
Sbjct: 62  KIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGDD 121

Query: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
           + PKD+ G  +         WEA+E+  D GL K++GVSNF+  Q+E +LNKPGLKYKPV
Sbjct: 122 LFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPV 181

Query: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKK 247
            NQVECHPY  Q KL+ +C SK I + AYS LGS  + PW  P  P LLEDP +  +A K
Sbjct: 182 TNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGS-PDRPWAKPEDPSLLEDPKIKEIAAK 240

Query: 248 HKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLT 307
           HK+T A + +R+ +QR V+V+ KS    RI +N+QVF+F+L+ EEM  I   NRN R   
Sbjct: 241 HKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACN 300

Query: 308 LDIFAGPPNYPFSDEY 323
           +   +   +YPF+ EY
Sbjct: 301 VLQSSHLEDYPFNAEY 316


>gi|122937516 aldo-keto reductase family 1, member B10-like [Homo
           sapiens]
          Length = 316

 Score =  292 bits (747), Expect = 3e-79
 Identities = 147/316 (46%), Positives = 201/316 (63%), Gaps = 4/316 (1%)

Query: 8   VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67
           V+L+    MP++G GT+        K  EA K+AI+A +RHID A+ Y N+ +VG AI+ 
Sbjct: 5   VELSTKAKMPIVGLGTWRSL---LGKVKEAVKVAIDAEYRHIDCAYFYENQHEVGEAIQE 61

Query: 68  KIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEE 127
           KI + +V RED+F  SK+W       LVR A E++LK+L+L Y+D+YLIH+P   K G++
Sbjct: 62  KIQEKAVMREDLFIVSKVWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKTGDD 121

Query: 128 VIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 187
             PKD+ G ++         WEA+E+  D GL K++GVSNFN  Q+E +LNKPGLKYKPV
Sbjct: 122 FFPKDDKGNMISGKGTFLDAWEAMEELVDEGLVKALGVSNFNHFQIERLLNKPGLKYKPV 181

Query: 188 CNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKK 247
            NQVECHPY  Q KL+ +C SK I + AYS LGS  + PW  P  P LLEDP +  +A K
Sbjct: 182 TNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGS-PDRPWAKPEDPSLLEDPKIKEIAAK 240

Query: 248 HKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLT 307
           HK+T A + +R+ +QR V V+ KS     I +N+QVF+F+L+ EEM  I   NRN R   
Sbjct: 241 HKKTTAQVLIRFHIQRNVTVIPKSMTPAHIVENIQVFDFKLSDEEMATILSFNRNWRAFD 300

Query: 308 LDIFAGPPNYPFSDEY 323
              F+   ++PF  EY
Sbjct: 301 FKEFSHLEDFPFDAEY 316


>gi|93277124 aldo-keto reductase family 1, member C-like 2 [Homo
           sapiens]
          Length = 320

 Score =  272 bits (696), Expect = 3e-73
 Identities = 139/327 (42%), Positives = 200/327 (61%), Gaps = 29/327 (8%)

Query: 16  MPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVK 75
           +P +G  ++   +    K  EA K AI+AG+RH D A+ Y+NE +VG  IR KI +G+V+
Sbjct: 4   IPAVGLSSW---KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVR 60

Query: 76  REDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGE--------- 126
           RED+F  +KLWC  H+  LV  A  +SLK L+L+Y+DLYLIH+P+  KP           
Sbjct: 61  REDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSE 120

Query: 127 ----------EVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMI 176
                     + +P DE+  ++    D   TWEA+E     GL K+IGVSNFN  QLE +
Sbjct: 121 LSFCLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERL 180

Query: 177 LNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLL 236
           LNKPGL++KP+ NQ+ECHPY  Q+ L+ FC+S+D+ + AY  LG   E   VD     L+
Sbjct: 181 LNKPGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLGGSCE--GVD-----LI 233

Query: 237 EDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAI 296
           ++PV+  +AK+H ++PA I +R+Q+QR V+V+  S     I++N+QVF+F+LT  +M  I
Sbjct: 234 DNPVIKRIAKEHGKSPAQILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNI 293

Query: 297 DGLNRNVRYLTLDIFAGPPNYPFSDEY 323
             LNRN+R     I     +YPF  EY
Sbjct: 294 LSLNRNLRLAMFPITKNHKDYPFHIEY 320


>gi|24497577 aldo-keto reductase family 1, member A1 [Homo sapiens]
          Length = 325

 Score =  271 bits (693), Expect = 6e-73
 Identities = 145/327 (44%), Positives = 214/327 (65%), Gaps = 16/327 (4%)

Query: 7   CVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIR 66
           CV L+ G  MP++G GT+  +E  + KA  A K A+  G+RHID A +Y NE ++G A++
Sbjct: 5   CVLLHTGQKMPLIGLGTWK-SEPGQVKA--AVKYALSVGYRHIDCAAIYGNEPEIGEALK 61

Query: 67  SKIADG-SVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPG 125
             +  G +V RE++F TSKLW   H PE V PAL ++L +LQL+Y+DLYL+H+P + + G
Sbjct: 62  EDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERG 121

Query: 126 EEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYK 185
           +   PK+ +G I +D+     TW+A+E     GL +++G+SNFN RQ++ IL+   +  +
Sbjct: 122 DNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASV--R 179

Query: 186 PVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALA 245
           P   QVECHPY  Q +L+  C+++ + + AYS LGS  +  W DP+ PVLLE+PV+ ALA
Sbjct: 180 PAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGS-SDRAWRDPDEPVLLEEPVVLALA 238

Query: 246 KKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRY 305
           +K+ R+PA I LR+Q+QR V+ + KS    RI QN++VF+F  + EEMK ++ LN+N RY
Sbjct: 239 EKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRY 298

Query: 306 ----LTLD-----IFAGPPNYPFSDEY 323
               LT+D       AG P YPF+D Y
Sbjct: 299 IVPMLTVDGKRVPRDAGHPLYPFNDPY 325


>gi|5174391 aldo-keto reductase family 1, member A1 [Homo sapiens]
          Length = 325

 Score =  271 bits (693), Expect = 6e-73
 Identities = 145/327 (44%), Positives = 214/327 (65%), Gaps = 16/327 (4%)

Query: 7   CVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIR 66
           CV L+ G  MP++G GT+  +E  + KA  A K A+  G+RHID A +Y NE ++G A++
Sbjct: 5   CVLLHTGQKMPLIGLGTWK-SEPGQVKA--AVKYALSVGYRHIDCAAIYGNEPEIGEALK 61

Query: 67  SKIADG-SVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPG 125
             +  G +V RE++F TSKLW   H PE V PAL ++L +LQL+Y+DLYL+H+P + + G
Sbjct: 62  EDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERG 121

Query: 126 EEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYK 185
           +   PK+ +G I +D+     TW+A+E     GL +++G+SNFN RQ++ IL+   +  +
Sbjct: 122 DNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASV--R 179

Query: 186 PVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALA 245
           P   QVECHPY  Q +L+  C+++ + + AYS LGS  +  W DP+ PVLLE+PV+ ALA
Sbjct: 180 PAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGS-SDRAWRDPDEPVLLEEPVVLALA 238

Query: 246 KKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRY 305
           +K+ R+PA I LR+Q+QR V+ + KS    RI QN++VF+F  + EEMK ++ LN+N RY
Sbjct: 239 EKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRY 298

Query: 306 ----LTLD-----IFAGPPNYPFSDEY 323
               LT+D       AG P YPF+D Y
Sbjct: 299 IVPMLTVDGKRVPRDAGHPLYPFNDPY 325


>gi|207028673 hypothetical protein LOC100134257 [Homo sapiens]
          Length = 139

 Score =  243 bits (620), Expect = 2e-64
 Identities = 119/123 (96%), Positives = 120/123 (97%)

Query: 1   MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQ 60
           MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEA KLAIEAGF HIDSAH+YNNEEQ
Sbjct: 1   MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQ 60

Query: 61  VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120
           VGLAIRSKIADGSVKREDIFYTSKLW NSHRPELVRPALERSLKNLQLDYVDLYLIHFPV
Sbjct: 61  VGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV 120

Query: 121 SVK 123
           SVK
Sbjct: 121 SVK 123


>gi|223718708 aflatoxin B1 aldehyde reductase 3 isoform 2 [Homo
           sapiens]
          Length = 249

 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 50/146 (34%), Positives = 69/146 (47%), Gaps = 17/146 (11%)

Query: 28  EVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQV----GLAIRSKIADGSVKREDIFYTS 83
           + P S A+  T+  +E G   ID+A LY++ +      GL +R   +D  VK   I   +
Sbjct: 24  DAPTSAAV--TRAFLERGHTEIDTAFLYSDGQSETILGGLGLRMGSSDCRVK---IATKA 78

Query: 84  KLWC-NSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVI----PKDENGKIL 138
             W  NS +P+ VR  LE SLK LQ   VDL+ +H P    P EE +       + GK +
Sbjct: 79  NPWIGNSLKPDSVRSQLETSLKRLQCPUVDLFYLHAPDHSAPVEETLRACHQLHQEGKFV 138

Query: 139 FDTVDLCATWEAVEKCKDAGLAKSIG 164
              +   A WE  E C    L KS G
Sbjct: 139 ELGLSNYAAWEVAEICT---LCKSNG 161


>gi|223718702 aflatoxin B1 aldehyde reductase 3 isoform 1 [Homo
           sapiens]
          Length = 331

 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 50/146 (34%), Positives = 69/146 (47%), Gaps = 17/146 (11%)

Query: 28  EVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQV----GLAIRSKIADGSVKREDIFYTS 83
           + P S A+  T+  +E G   ID+A LY++ +      GL +R   +D  VK   I   +
Sbjct: 24  DAPTSAAV--TRAFLERGHTEIDTAFLYSDGQSETILGGLGLRMGSSDCRVK---IATKA 78

Query: 84  KLWC-NSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVI----PKDENGKIL 138
             W  NS +P+ VR  LE SLK LQ   VDL+ +H P    P EE +       + GK +
Sbjct: 79  NPWIGNSLKPDSVRSQLETSLKRLQCPUVDLFYLHAPDHSAPVEETLRACHQLHQEGKFV 138

Query: 139 FDTVDLCATWEAVEKCKDAGLAKSIG 164
              +   A WE  E C    L KS G
Sbjct: 139 ELGLSNYAAWEVAEICT---LCKSNG 161


>gi|41152114 aldo-keto reductase family 7, member A3 [Homo sapiens]
          Length = 331

 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 47/145 (32%), Positives = 68/145 (46%), Gaps = 15/145 (10%)

Query: 28  EVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQV----GLAIRSKIADGSVKREDIFYTS 83
           + P S A+  T+  +E G   ID+A +Y+  +      GL +R   +D  VK +      
Sbjct: 24  DAPTSAAV--TRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDT--KAI 79

Query: 84  KLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVI----PKDENGKILF 139
            L+ NS +P+ +R  LE SLK LQ   VDL+ +H P    P EE +       + GK + 
Sbjct: 80  PLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEETLRACHQLHQEGKFVE 139

Query: 140 DTVDLCATWEAVEKCKDAGLAKSIG 164
             +   A WE  E C    L KS G
Sbjct: 140 LGLSNYAAWEVAEICT---LCKSNG 161


>gi|41327764 aldo-keto reductase family 7, member A2 [Homo sapiens]
          Length = 359

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 46/146 (31%), Positives = 66/146 (45%), Gaps = 17/146 (11%)

Query: 28  EVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQV----GLAIRSKIADGSVKREDIFYTS 83
           + P S A  A +  +E G   +D+A +Y++ +      GL +     D  VK   I   +
Sbjct: 52  DAPASAA--AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVK---IATKA 106

Query: 84  KLWCN-SHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPK----DENGKIL 138
             W   S +P+ VR  LE SLK LQ   VDL+ +H P    P EE +       + GK +
Sbjct: 107 NPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVEETLHACQRLHQEGKFV 166

Query: 139 FDTVDLCATWEAVEKCKDAGLAKSIG 164
              +   A+WE  E C    L KS G
Sbjct: 167 ELGLSNYASWEVAEICT---LCKSNG 189


>gi|27436964 potassium voltage-gated channel, shaker-related
           subfamily, beta member 1 isoform 3 [Homo sapiens]
          Length = 401

 Score = 39.3 bits (90), Expect = 0.005
 Identities = 50/199 (25%), Positives = 81/199 (40%), Gaps = 43/199 (21%)

Query: 19  LGFGTYAP--AEVPKSKALEATKLAIEAGFRHIDSAHLY---NNEEQVGLAIRSKIADGS 73
           LG GT+     ++    A     +A E+G    D+A +Y     E  +G  I+ K     
Sbjct: 86  LGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKK----G 141

Query: 74  VKREDIFYTSKL-WCNSHRPEL------VRPALERSLKNLQLDYVDLYLIHFPVSVKPGE 126
            +R  +  T+KL W      E       +   L+ SL+ LQL+YVD+   + P S  P E
Sbjct: 142 WRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPME 201

Query: 127 EVIPK-----DENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
           E++       ++   + + T    + W A+E  +   +A          RQ  MI     
Sbjct: 202 EIVRAMTHVINQGMAMYWGT----SRWSAMEIMEAYSVA----------RQFNMI----- 242

Query: 182 LKYKPVCNQVECHPYFNQR 200
               PVC Q E H +  ++
Sbjct: 243 ---PPVCEQAEYHLFQREK 258


>gi|27436962 potassium voltage-gated channel, shaker-related
           subfamily, beta member 1 isoform 2 [Homo sapiens]
          Length = 408

 Score = 39.3 bits (90), Expect = 0.005
 Identities = 50/199 (25%), Positives = 81/199 (40%), Gaps = 43/199 (21%)

Query: 19  LGFGTYAP--AEVPKSKALEATKLAIEAGFRHIDSAHLY---NNEEQVGLAIRSKIADGS 73
           LG GT+     ++    A     +A E+G    D+A +Y     E  +G  I+ K     
Sbjct: 93  LGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKK----G 148

Query: 74  VKREDIFYTSKL-WCNSHRPEL------VRPALERSLKNLQLDYVDLYLIHFPVSVKPGE 126
            +R  +  T+KL W      E       +   L+ SL+ LQL+YVD+   + P S  P E
Sbjct: 149 WRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPME 208

Query: 127 EVIPK-----DENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
           E++       ++   + + T    + W A+E  +   +A          RQ  MI     
Sbjct: 209 EIVRAMTHVINQGMAMYWGT----SRWSAMEIMEAYSVA----------RQFNMI----- 249

Query: 182 LKYKPVCNQVECHPYFNQR 200
               PVC Q E H +  ++
Sbjct: 250 ---PPVCEQAEYHLFQREK 265


>gi|27436966 potassium voltage-gated channel, shaker-related
           subfamily, beta member 1 isoform 1 [Homo sapiens]
          Length = 419

 Score = 39.3 bits (90), Expect = 0.005
 Identities = 50/199 (25%), Positives = 81/199 (40%), Gaps = 43/199 (21%)

Query: 19  LGFGTYAP--AEVPKSKALEATKLAIEAGFRHIDSAHLY---NNEEQVGLAIRSKIADGS 73
           LG GT+     ++    A     +A E+G    D+A +Y     E  +G  I+ K     
Sbjct: 104 LGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKK----G 159

Query: 74  VKREDIFYTSKL-WCNSHRPEL------VRPALERSLKNLQLDYVDLYLIHFPVSVKPGE 126
            +R  +  T+KL W      E       +   L+ SL+ LQL+YVD+   + P S  P E
Sbjct: 160 WRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPME 219

Query: 127 EVIPK-----DENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
           E++       ++   + + T    + W A+E  +   +A          RQ  MI     
Sbjct: 220 EIVRAMTHVINQGMAMYWGT----SRWSAMEIMEAYSVA----------RQFNMI----- 260

Query: 182 LKYKPVCNQVECHPYFNQR 200
               PVC Q E H +  ++
Sbjct: 261 ---PPVCEQAEYHLFQREK 276


>gi|4504825 potassium voltage-gated channel, shaker-related
           subfamily, beta member 2 isoform 1 [Homo sapiens]
          Length = 367

 Score = 34.3 bits (77), Expect = 0.15
 Identities = 33/123 (26%), Positives = 53/123 (43%), Gaps = 16/123 (13%)

Query: 19  LGFGTYAP--AEVPKSKALEATKLAIEAGFRHIDSAHLY---NNEEQVGLAIRSKIADGS 73
           LG GT+     ++    A +   LA + G    D+A +Y     E  +G  I+ K     
Sbjct: 52  LGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKK----G 107

Query: 74  VKREDIFYTSKL-WCNSHRPEL------VRPALERSLKNLQLDYVDLYLIHFPVSVKPGE 126
            +R  +  T+K+ W      E       +   L+ SL+ LQL+YVD+   + P    P E
Sbjct: 108 WRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRPDPNTPME 167

Query: 127 EVI 129
           E +
Sbjct: 168 ETV 170


>gi|27436969 potassium voltage-gated channel, shaker-related
           subfamily, beta member 2 isoform 2 [Homo sapiens]
          Length = 353

 Score = 34.3 bits (77), Expect = 0.15
 Identities = 33/123 (26%), Positives = 53/123 (43%), Gaps = 16/123 (13%)

Query: 19  LGFGTYAP--AEVPKSKALEATKLAIEAGFRHIDSAHLY---NNEEQVGLAIRSKIADGS 73
           LG GT+     ++    A +   LA + G    D+A +Y     E  +G  I+ K     
Sbjct: 38  LGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKK----G 93

Query: 74  VKREDIFYTSKL-WCNSHRPEL------VRPALERSLKNLQLDYVDLYLIHFPVSVKPGE 126
            +R  +  T+K+ W      E       +   L+ SL+ LQL+YVD+   + P    P E
Sbjct: 94  WRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRPDPNTPME 153

Query: 127 EVI 129
           E +
Sbjct: 154 ETV 156


>gi|27436971 potassium voltage-gated channel, shaker-related
           subfamily, beta member 3 [Homo sapiens]
          Length = 404

 Score = 31.2 bits (69), Expect = 1.3
 Identities = 32/123 (26%), Positives = 52/123 (42%), Gaps = 16/123 (13%)

Query: 19  LGFGTYAP--AEVPKSKALEATKLAIEAGFRHIDSAHLY---NNEEQVGLAIRSKIADGS 73
           LG GT+    +++    A +   +A E G    D+A +Y     E  +G  ++SK     
Sbjct: 93  LGLGTWVTFGSQISDETAEDVLTVAYEHGVNLFDTAEVYAAGKAERTLGNILKSK----G 148

Query: 74  VKREDIFYTSKL-WCNSHRPEL------VRPALERSLKNLQLDYVDLYLIHFPVSVKPGE 126
            +R     T+K+ W      E       +   L  SL+ LQL YVD+   +      P E
Sbjct: 149 WRRSSYVITTKIFWGGQAETERGLSRKHIIEGLRGSLERLQLGYVDIVFANRSDPNCPME 208

Query: 127 EVI 129
           E++
Sbjct: 209 EIV 211


>gi|4503503 eukaryotic translation initiation factor 2B, subunit 1
           alpha, 26kDa [Homo sapiens]
          Length = 305

 Score = 30.8 bits (68), Expect = 1.7
 Identities = 22/76 (28%), Positives = 33/76 (43%), Gaps = 15/76 (19%)

Query: 176 ILNKPGLKYKPVCNQVECHPYF--------------NQRKLLDFCKSK-DIVLVAYSALG 220
           I+NK G     VC + +  P++              NQ+ + D  K K D + VA +   
Sbjct: 206 IINKIGTNQMAVCAKAQNKPFYVVAESFKFVRLFPLNQQDVPDKFKYKADTLKVAQTGQD 265

Query: 221 SHREEPWVDPNSPVLL 236
              E PWVD  +P L+
Sbjct: 266 LKEEHPWVDYTAPSLI 281


>gi|193211614 NAD(P) dependent steroid dehydrogenase-like [Homo
           sapiens]
          Length = 373

 Score = 30.0 bits (66), Expect = 2.9
 Identities = 15/38 (39%), Positives = 20/38 (52%)

Query: 130 PKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSN 167
           P   N K LF  V+   T   +E CK+AG+ K I  S+
Sbjct: 108 PPSSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTSS 145


>gi|8393516 NAD(P) dependent steroid dehydrogenase-like [Homo
           sapiens]
          Length = 373

 Score = 30.0 bits (66), Expect = 2.9
 Identities = 15/38 (39%), Positives = 20/38 (52%)

Query: 130 PKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSN 167
           P   N K LF  V+   T   +E CK+AG+ K I  S+
Sbjct: 108 PPSSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTSS 145


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,724,225
Number of Sequences: 37866
Number of extensions: 545965
Number of successful extensions: 1016
Number of sequences better than 10.0: 26
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 975
Number of HSP's gapped (non-prelim): 26
length of query: 323
length of database: 18,247,518
effective HSP length: 102
effective length of query: 221
effective length of database: 14,385,186
effective search space: 3179126106
effective search space used: 3179126106
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.