Search of human proteins with 5453541

Search of human proteins with 5453541

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5453541 anterior gradient 2 homolog [Homo sapiens]
         (175 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5453541 anterior gradient 2 homolog [Homo sapiens]                 350   3e-97
gi|28827801 breast cancer membrane protein 11 [Homo sapiens]          214   3e-56
gi|7705696 thioredoxin domain containing 12 [Homo sapiens]             87   6e-18
gi|215982794 myosin VA isoform 2 [Homo sapiens]                        32   0.37 
gi|215982791 myosin VA isoform 1 [Homo sapiens]                        32   0.37 
gi|109255234 centrosomal protein 290kDa [Homo sapiens]                 29   1.8  
gi|122937345 myosin VB [Homo sapiens]                                  28   4.1  
gi|47933339 RNA binding motif protein 15 [Homo sapiens]                28   4.1  
gi|134244285 Notch homolog 3 [Homo sapiens]                            28   5.3  
gi|51873049 hypothetical protein LOC8603 [Homo sapiens]                28   5.3  
gi|31542723 spermatogenesis associated 20 [Homo sapiens]               28   5.3  
gi|66529203 hypothetical protein LOC57714 [Homo sapiens]               28   5.3  
gi|223029500 EF-hand calcium binding domain 5 isoform b [Homo sa...    27   6.9  
gi|90652855 EF-hand calcium binding domain 5 isoform a [Homo sap...    27   6.9  
gi|134133279 SP140 nuclear body protein-like [Homo sapiens]            27   9.0  
gi|67551265 transcription factor ELYS [Homo sapiens]                   27   9.0  
gi|91754185 hypothetical protein LOC254268 [Homo sapiens]              27   9.0  

>gi|5453541 anterior gradient 2 homolog [Homo sapiens]
          Length = 175

 Score =  350 bits (899), Expect = 3e-97
 Identities = 175/175 (100%), Positives = 175/175 (100%)

Query: 1   MEKIPVSAFLLLVALSYTLARDTTVKPGAKKDTKDSRPKLPQTLSRGWGDQLIWTQTYEE 60
           MEKIPVSAFLLLVALSYTLARDTTVKPGAKKDTKDSRPKLPQTLSRGWGDQLIWTQTYEE
Sbjct: 1   MEKIPVSAFLLLVALSYTLARDTTVKPGAKKDTKDSRPKLPQTLSRGWGDQLIWTQTYEE 60

Query: 61  ALYKSKTSNKPLMIIHHLDECPHSQALKKVFAENKEIQKLAEQFVLLNLVYETTDKHLSP 120
           ALYKSKTSNKPLMIIHHLDECPHSQALKKVFAENKEIQKLAEQFVLLNLVYETTDKHLSP
Sbjct: 61  ALYKSKTSNKPLMIIHHLDECPHSQALKKVFAENKEIQKLAEQFVLLNLVYETTDKHLSP 120

Query: 121 DGQYVPRIMFVDPSLTVRADITGRYSNRLYAYEPADTALLLDNMKKALKLLKTEL 175
           DGQYVPRIMFVDPSLTVRADITGRYSNRLYAYEPADTALLLDNMKKALKLLKTEL
Sbjct: 121 DGQYVPRIMFVDPSLTVRADITGRYSNRLYAYEPADTALLLDNMKKALKLLKTEL 175


>gi|28827801 breast cancer membrane protein 11 [Homo sapiens]
          Length = 166

 Score =  214 bits (545), Expect = 3e-56
 Identities = 108/167 (64%), Positives = 136/167 (81%), Gaps = 12/167 (7%)

Query: 10  LLLVALSYTLARDTTVKPGAKKDTKDSRPKLPQTLSRGWGDQLIWTQTYEEALYKSKTSN 69
           LLLV +S  LA    +K       K+ RP  PQTLSRGWGD + W QTYEE L+ ++ S 
Sbjct: 11  LLLVTVSSNLA--IAIK-------KEKRP--PQTLSRGWGDDITWVQTYEEGLFYAQKSK 59

Query: 70  KPLMIIHHLDECPHSQALKKVFAENKEIQKLAE-QFVLLNLVYETTDKHLSPDGQYVPRI 128
           KPLM+IHHL++C +SQALKKVFA+N+EIQ++A+ +F++LNL++ETTDK+LSPDGQYVPRI
Sbjct: 60  KPLMVIHHLEDCQYSQALKKVFAQNEEIQEMAQNKFIMLNLMHETTDKNLSPDGQYVPRI 119

Query: 129 MFVDPSLTVRADITGRYSNRLYAYEPADTALLLDNMKKALKLLKTEL 175
           MFVDPSLTVRADI GRYSNRLY YEP D  LL++NMKKAL+L+++EL
Sbjct: 120 MFVDPSLTVRADIAGRYSNRLYTYEPRDLPLLIENMKKALRLIQSEL 166


>gi|7705696 thioredoxin domain containing 12 [Homo sapiens]
          Length = 172

 Score = 87.4 bits (215), Expect = 6e-18
 Identities = 50/130 (38%), Positives = 73/130 (56%), Gaps = 3/130 (2%)

Query: 44  LSRGWGDQLIWTQTYEEALYKSKTSNKPLMIIHHLDECPHSQALKKVFAENKEIQKLAEQ 103
           L +G+GD + W +T E+   ++  S  PLM+I H   C   +ALK  FAE+ EI +L+  
Sbjct: 30  LGKGFGDHIHW-RTLEDGKKEAAASGLPLMVIIHKSWCGACKALKPKFAESTEISELSHN 88

Query: 104 FVLLNLV--YETTDKHLSPDGQYVPRIMFVDPSLTVRADITGRYSNRLYAYEPADTALLL 161
           FV++NL    E  D+  SPDG Y+PRI+F+DPS  V  +I     N  Y Y       ++
Sbjct: 89  FVMVNLEDEEEPKDEDFSPDGGYIPRILFLDPSGKVHPEIINENGNPSYKYFYVSAEQVV 148

Query: 162 DNMKKALKLL 171
             MK+A + L
Sbjct: 149 QGMKEAQERL 158


>gi|215982794 myosin VA isoform 2 [Homo sapiens]
          Length = 1828

 Score = 31.6 bits (70), Expect = 0.37
 Identities = 25/96 (26%), Positives = 45/96 (46%), Gaps = 8/96 (8%)

Query: 32  DTKDSRPKLPQTLSRGWGDQLIWTQTYEEALY-KSKTSNKPLMIIHHLDECPH------S 84
           D  D   K+P+     W  +L  T   + AL+ K + SNK  +I H  D+  +       
Sbjct: 507 DLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEKPRLSNKAFIIQHFADKVEYQCEGFLE 566

Query: 85  QALKKVFAENKEIQKLAEQFVLLNLVYETTDKHLSP 120
           +    VF E  ++ K + +F +L  +++  +K +SP
Sbjct: 567 KNKDTVFEEQIKVLK-SSKFKMLPELFQDDEKAISP 601


>gi|215982791 myosin VA isoform 1 [Homo sapiens]
          Length = 1855

 Score = 31.6 bits (70), Expect = 0.37
 Identities = 25/96 (26%), Positives = 45/96 (46%), Gaps = 8/96 (8%)

Query: 32  DTKDSRPKLPQTLSRGWGDQLIWTQTYEEALY-KSKTSNKPLMIIHHLDECPH------S 84
           D  D   K+P+     W  +L  T   + AL+ K + SNK  +I H  D+  +       
Sbjct: 507 DLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEKPRLSNKAFIIQHFADKVEYQCEGFLE 566

Query: 85  QALKKVFAENKEIQKLAEQFVLLNLVYETTDKHLSP 120
           +    VF E  ++ K + +F +L  +++  +K +SP
Sbjct: 567 KNKDTVFEEQIKVLK-SSKFKMLPELFQDDEKAISP 601


>gi|109255234 centrosomal protein 290kDa [Homo sapiens]
          Length = 2479

 Score = 29.3 bits (64), Expect = 1.8
 Identities = 16/48 (33%), Positives = 31/48 (64%), Gaps = 1/48 (2%)

Query: 59  EEALYKSKTSNKPLMIIHHLDECPH-SQALKKVFAENKEIQKLAEQFV 105
           E++ Y+S+ S K   +I +LDE    ++A +K+  +N+E++K  E+ V
Sbjct: 200 EDSDYRSQLSKKNYELIQYLDEIQTLTEANEKIEVQNQEMRKNLEESV 247


>gi|122937345 myosin VB [Homo sapiens]
          Length = 1848

 Score = 28.1 bits (61), Expect = 4.1
 Identities = 18/76 (23%), Positives = 30/76 (39%), Gaps = 3/76 (3%)

Query: 32  DTKDSRPKLPQTLSRGWGDQLIWTQTYEEALYKSKTSNKPLMIIHHLDECPHSQALKKVF 91
           D  D   K+P+   + W  +L    +  +   K + SN   +I+H  D+  +   L   F
Sbjct: 508 DLLDEECKVPKGTDQNWAQKLYDRHSSSQHFQKPRMSNTAFIIVHFADKVEY---LSDGF 564

Query: 92  AENKEIQKLAEQFVLL 107
            E        EQ  +L
Sbjct: 565 LEKNRDTVYEEQINIL 580


>gi|47933339 RNA binding motif protein 15 [Homo sapiens]
          Length = 977

 Score = 28.1 bits (61), Expect = 4.1
 Identities = 17/49 (34%), Positives = 23/49 (46%), Gaps = 6/49 (12%)

Query: 109 LVYETTDKHLSPDGQYVPRIMFVDPSLTVRADITGRYSNRLYAYEPADT 157
           L+Y   D+ L PD  +VP      P   VR   T   +  + AYEP D+
Sbjct: 571 LLYRDRDRDLYPDSDWVP------PPPPVRERSTRTAATSVPAYEPLDS 613


>gi|134244285 Notch homolog 3 [Homo sapiens]
          Length = 2321

 Score = 27.7 bits (60), Expect = 5.3
 Identities = 28/104 (26%), Positives = 50/104 (48%), Gaps = 13/104 (12%)

Query: 1    MEKIPVSAFLLLVALSYTLARDTTVKPGAKKDTKDSRPKLPQTLSRGWGDQLIWTQTYEE 60
            ++++  SA     A++   A    +K GA KD +DS+ + P  L+   G       +YE 
Sbjct: 1935 VDELGKSALHWAAAVNNVEATLALLKNGANKDMQDSKEETPLFLAAREG-------SYEA 1987

Query: 61   A-LYKSKTSNKPLMIIHHLDECPHSQALKKVFAENKEIQKLAEQ 103
            A L     +N+   I  HLD  P   A +++   +++I +L +Q
Sbjct: 1988 AKLLLDHFANRE--ITDHLDRLPRDVAQERL---HQDIVRLLDQ 2026


>gi|51873049 hypothetical protein LOC8603 [Homo sapiens]
          Length = 1224

 Score = 27.7 bits (60), Expect = 5.3
 Identities = 15/59 (25%), Positives = 30/59 (50%)

Query: 85  QALKKVFAENKEIQKLAEQFVLLNLVYETTDKHLSPDGQYVPRIMFVDPSLTVRADITG 143
           + L++V  E  E QK  + +V   +  +T  + L+ D +   +  F++  LT +  +TG
Sbjct: 123 EELRRVAEEWLECQKRIDAYVDEQMTMKTKQRMLTEDWELFKQRRFIEEQLTNKKAVTG 181


>gi|31542723 spermatogenesis associated 20 [Homo sapiens]
          Length = 802

 Score = 27.7 bits (60), Expect = 5.3
 Identities = 27/117 (23%), Positives = 48/117 (41%), Gaps = 17/117 (14%)

Query: 16  SYTLARDTTVKPGAKKDTKDSRP----------KLPQTLSRGWGDQLIWTQTYEEALYKS 65
           S T++    +  G K     S P          K P  L   + + + W    +EA  K+
Sbjct: 52  SATVSSSVPMPAGGKGSHPSSTPQRVPNRLIHEKSPYLLQHAY-NPVDWYPWGQEAFDKA 110

Query: 66  KTSNKPLMIIHHLDECPHSQALKKVFAENKEIQK-LAEQFVLLNLVYETTDKHLSPD 121
           +  NKP+ +      C     +++   +N+EI + L+E FV + +     D+   PD
Sbjct: 111 RKENKPIFLSVGYSTCHWCHMMEEESFQNEEIGRLLSEDFVSVKV-----DREERPD 162


>gi|66529203 hypothetical protein LOC57714 [Homo sapiens]
          Length = 1063

 Score = 27.7 bits (60), Expect = 5.3
 Identities = 20/72 (27%), Positives = 33/72 (45%), Gaps = 6/72 (8%)

Query: 75  IHHLDECPHSQALKK--VFAENKEIQK-LAEQFVLLN---LVYETTDKHLSPDGQYVPRI 128
           +H+  +  H + L +  V    K + K +  ++V+ N     YE   KH    G+YV R 
Sbjct: 420 LHYTRDLGHDRVLVEGIVCISKKHLDKYIPYKYVIYNGESFEYEFIYKHQQKKGEYVNRC 479

Query: 129 MFVDPSLTVRAD 140
           +F+  SL    D
Sbjct: 480 LFIKSSLLGSGD 491


>gi|223029500 EF-hand calcium binding domain 5 isoform b [Homo
           sapiens]
          Length = 856

 Score = 27.3 bits (59), Expect = 6.9
 Identities = 18/74 (24%), Positives = 29/74 (39%), Gaps = 8/74 (10%)

Query: 26  KPGAKKDTKDSRPKLPQTLSRGWGDQLIWTQTYEEALYKSKTSNKPLMIIHHLDECPHSQ 85
           K    K TK   P   + +     ++  W QTYEE ++ S    + +  +   D  P + 
Sbjct: 619 KDSILKSTKYGEPITSEYIEVPLQEKRSWEQTYEEEIFLSSELQEEVPTLSRKDHFPET- 677

Query: 86  ALKKVFAENKEIQK 99
                    KE+QK
Sbjct: 678 -------TKKEVQK 684


>gi|90652855 EF-hand calcium binding domain 5 isoform a [Homo
           sapiens]
          Length = 1503

 Score = 27.3 bits (59), Expect = 6.9
 Identities = 18/74 (24%), Positives = 29/74 (39%), Gaps = 8/74 (10%)

Query: 26  KPGAKKDTKDSRPKLPQTLSRGWGDQLIWTQTYEEALYKSKTSNKPLMIIHHLDECPHSQ 85
           K    K TK   P   + +     ++  W QTYEE ++ S    + +  +   D  P + 
Sbjct: 675 KDSILKSTKYGEPITSEYIEVPLQEKRSWEQTYEEEIFLSSELQEEVPTLSRKDHFPET- 733

Query: 86  ALKKVFAENKEIQK 99
                    KE+QK
Sbjct: 734 -------TKKEVQK 740


>gi|134133279 SP140 nuclear body protein-like [Homo sapiens]
          Length = 580

 Score = 26.9 bits (58), Expect = 9.0
 Identities = 12/35 (34%), Positives = 22/35 (62%), Gaps = 8/35 (22%)

Query: 83  HSQALKKVFAENKEIQKLAEQFVLLNLVYETTDKH 117
           HSQ+L+++F E++++ +         LVY+T  KH
Sbjct: 30  HSQSLQRLFTEDQDVDE--------GLVYDTVFKH 56


>gi|67551265 transcription factor ELYS [Homo sapiens]
          Length = 2266

 Score = 26.9 bits (58), Expect = 9.0
 Identities = 22/88 (25%), Positives = 38/88 (43%), Gaps = 17/88 (19%)

Query: 51   QLIWTQTYEEALYK-----SKTSNKPLMIIHHLDECPHSQALK-----KVFAENKEIQKL 100
            +L +T T +E L K     +   N   +++HHL    +  ALK     K+   N    +L
Sbjct: 927  KLPFTDTEQECLVKFLQSSASVQNHEFLLVHHLQRANYVPALKLNQTLKINVMNDRDPRL 986

Query: 101  AEQFVLLNLVYETTDKHLSPDGQYVPRI 128
             E+ +  N +       L   G+ +PR+
Sbjct: 987  RERSLARNSI-------LDQYGKILPRV 1007


>gi|91754185 hypothetical protein LOC254268 [Homo sapiens]
          Length = 836

 Score = 26.9 bits (58), Expect = 9.0
 Identities = 14/54 (25%), Positives = 31/54 (57%), Gaps = 1/54 (1%)

Query: 59  EEALYKSKTSNKPLMIIHHLDECPHSQALKKVFAENK-EIQKLAEQFVLLNLVY 111
           ++A + SK+ +KP ++   L+  P S  ++K   E K +I + ++Q  +  +V+
Sbjct: 284 KQASFSSKSRDKPTLVQDSLETTPESNCVEKQHQEQKGKITEPSQQIQMEPIVH 337


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.132    0.380 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,101,994
Number of Sequences: 37866
Number of extensions: 241134
Number of successful extensions: 596
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 586
Number of HSP's gapped (non-prelim): 20
length of query: 175
length of database: 18,247,518
effective HSP length: 95
effective length of query: 80
effective length of database: 14,650,248
effective search space: 1172019840
effective search space used: 1172019840
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.