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Search of human proteins with 53831995
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|53831995 splicing factor 3a, subunit 1, 120kDa isoform 2
[Homo sapiens]
(728 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|53831995 splicing factor 3a, subunit 1, 120kDa isoform 2 [Hom... 1488 0.0
gi|5032087 splicing factor 3a, subunit 1, 120kDa isoform 1 [Homo... 1373 0.0
gi|110349719 titin isoform N2-A [Homo sapiens] 96 2e-19
gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Ho... 80 5e-15
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 78 3e-14
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 78 3e-14
gi|146134388 YLP motif containing 1 [Homo sapiens] 76 1e-13
gi|160707881 formin 2 [Homo sapiens] 75 2e-13
gi|23111062 splicing factor, arginine/serine-rich 8 [Homo sapiens] 75 3e-13
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 74 4e-13
gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3 ... 72 2e-12
gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2 ... 72 2e-12
gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1 [... 72 2e-12
gi|210032580 SET domain containing 1B [Homo sapiens] 72 2e-12
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 72 2e-12
gi|47132519 Ras association and pleckstrin homology domains 1 is... 72 2e-12
gi|116284392 mucin 2 precursor [Homo sapiens] 71 3e-12
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap... 71 4e-12
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 70 5e-12
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap... 70 7e-12
gi|153792074 proline rich 12 [Homo sapiens] 70 7e-12
gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Ho... 69 1e-11
gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Ho... 69 1e-11
gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Ho... 69 1e-11
gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Hom... 69 1e-11
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 69 1e-11
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 69 1e-11
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 69 1e-11
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens] 69 2e-11
gi|7706501 WW domain binding protein 11 [Homo sapiens] 69 2e-11
>gi|53831995 splicing factor 3a, subunit 1, 120kDa isoform 2 [Homo
sapiens]
Length = 728
Score = 1488 bits (3851), Expect = 0.0
Identities = 728/728 (100%), Positives = 728/728 (100%)
Query: 1 MPAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPPEVRNIVDKTASFV 60
MPAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPPEVRNIVDKTASFV
Sbjct: 1 MPAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPPEVRNIVDKTASFV 60
Query: 61 ARNGPEFEARIRQNEINNPKFNFLNPNDPYHAYYRHKVSEFKEGKAQFVARNGRQFLTQL 120
ARNGPEFEARIRQNEINNPKFNFLNPNDPYHAYYRHKVSEFKEGKAQFVARNGRQFLTQL
Sbjct: 61 ARNGPEFEARIRQNEINNPKFNFLNPNDPYHAYYRHKVSEFKEGKAQFVARNGRQFLTQL 120
Query: 121 MQKEQRNYQFDFLRPQHSLFNYFTKLVEQYTKILIPPKGLFSKLKKEAENPREVLDQVCY 180
MQKEQRNYQFDFLRPQHSLFNYFTKLVEQYTKILIPPKGLFSKLKKEAENPREVLDQVCY
Sbjct: 121 MQKEQRNYQFDFLRPQHSLFNYFTKLVEQYTKILIPPKGLFSKLKKEAENPREVLDQVCY 180
Query: 181 RVEWAKFQERERKKEEEEKEKERVAYAQIDWHDFVVVETVDFQPNEQGNFPPPTTPEELG 240
RVEWAKFQERERKKEEEEKEKERVAYAQIDWHDFVVVETVDFQPNEQGNFPPPTTPEELG
Sbjct: 181 RVEWAKFQERERKKEEEEKEKERVAYAQIDWHDFVVVETVDFQPNEQGNFPPPTTPEELG 240
Query: 241 ARILIQERYEKFGESEEVEMEVESDEEDDKQEKAEEPPSQLDQDTQVQDMDEGSDDEEEG 300
ARILIQERYEKFGESEEVEMEVESDEEDDKQEKAEEPPSQLDQDTQVQDMDEGSDDEEEG
Sbjct: 241 ARILIQERYEKFGESEEVEMEVESDEEDDKQEKAEEPPSQLDQDTQVQDMDEGSDDEEEG 300
Query: 301 QKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKM 360
QKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKM
Sbjct: 301 QKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKM 360
Query: 361 QEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGVEETAIG 420
QEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGVEETAIG
Sbjct: 361 QEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGVEETAIG 420
Query: 421 KKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKAKGLVPEDDTKEKI 480
KKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKAKGLVPEDDTKEKI
Sbjct: 421 KKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKAKGLVPEDDTKEKI 480
Query: 481 GPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASV 540
GPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASV
Sbjct: 481 GPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASV 540
Query: 541 VRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPA 600
VRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPA
Sbjct: 541 VRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPA 600
Query: 601 PMPPVHPPPPMEDEPTSKKLKTEDSLMPEEEFLRRNKGPVSIKVQVPNMQDKTEWKLNGQ 660
PMPPVHPPPPMEDEPTSKKLKTEDSLMPEEEFLRRNKGPVSIKVQVPNMQDKTEWKLNGQ
Sbjct: 601 PMPPVHPPPPMEDEPTSKKLKTEDSLMPEEEFLRRNKGPVSIKVQVPNMQDKTEWKLNGQ 660
Query: 661 VLVFTLPLTDQVSVIKVKIHEATGMPAGKQKLQYEGIFIKDSNSLAYYNMANGAVIHLAL 720
VLVFTLPLTDQVSVIKVKIHEATGMPAGKQKLQYEGIFIKDSNSLAYYNMANGAVIHLAL
Sbjct: 661 VLVFTLPLTDQVSVIKVKIHEATGMPAGKQKLQYEGIFIKDSNSLAYYNMANGAVIHLAL 720
Query: 721 KERGGRKK 728
KERGGRKK
Sbjct: 721 KERGGRKK 728
>gi|5032087 splicing factor 3a, subunit 1, 120kDa isoform 1 [Homo
sapiens]
Length = 793
Score = 1373 bits (3554), Expect = 0.0
Identities = 697/793 (87%), Positives = 710/793 (89%), Gaps = 65/793 (8%)
Query: 1 MPAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPPEVRNIVDKTASFV 60
MPAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPPEVRNIVDKTASFV
Sbjct: 1 MPAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPPEVRNIVDKTASFV 60
Query: 61 ARNGPEFEARIRQNEINNPKFNFLNPNDPYHAYYRHKVSEFKEGKAQ--------FVARN 112
ARNGPEFEARIRQNEINNPKFNFLNPNDPYHAYYRHKVSEFKEGKAQ + +
Sbjct: 61 ARNGPEFEARIRQNEINNPKFNFLNPNDPYHAYYRHKVSEFKEGKAQEPSAAIPKVMQQQ 120
Query: 113 GRQFLTQLMQKEQRNY------------QFDFLR--PQHSLFN----------------- 141
+ QL QK Q +F+F+ P S F+
Sbjct: 121 QQTTQQQLPQKVQAQVIQETIVPKEPPPEFEFIADPPSISAFDLDVVKLTAQFVARNGRQ 180
Query: 142 YFTKLVEQ-------------------YTK-------ILIPPKGLFSKLKKEAENPREVL 175
+ T+L+++ +TK ILIPPKGLFSKLKKEAENPREVL
Sbjct: 181 FLTQLMQKEQRNYQFDFLRPQHSLFNYFTKLVEQYTKILIPPKGLFSKLKKEAENPREVL 240
Query: 176 DQVCYRVEWAKFQERERKKEEEEKEKERVAYAQIDWHDFVVVETVDFQPNEQGNFPPPTT 235
DQVCYRVEWAKFQERERKKEEEEKEKERVAYAQIDWHDFVVVETVDFQPNEQGNFPPPTT
Sbjct: 241 DQVCYRVEWAKFQERERKKEEEEKEKERVAYAQIDWHDFVVVETVDFQPNEQGNFPPPTT 300
Query: 236 PEELGARILIQERYEKFGESEEVEMEVESDEEDDKQEKAEEPPSQLDQDTQVQDMDEGSD 295
PEELGARILIQERYEKFGESEEVEMEVESDEEDDKQEKAEEPPSQLDQDTQVQDMDEGSD
Sbjct: 301 PEELGARILIQERYEKFGESEEVEMEVESDEEDDKQEKAEEPPSQLDQDTQVQDMDEGSD 360
Query: 296 DEEEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKI 355
DEEEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKI
Sbjct: 361 DEEEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKI 420
Query: 356 PASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGVE 415
PASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGVE
Sbjct: 421 PASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGVE 480
Query: 416 ETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKAKGLVPEDD 475
ETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKAKGLVPEDD
Sbjct: 481 ETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKAKGLVPEDD 540
Query: 476 TKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRP 535
TKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRP
Sbjct: 541 TKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRP 600
Query: 536 PMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAP 595
PMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAP
Sbjct: 601 PMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAP 660
Query: 596 VPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMPEEEFLRRNKGPVSIKVQVPNMQDKTEW 655
VPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMPEEEFLRRNKGPVSIKVQVPNMQDKTEW
Sbjct: 661 VPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMPEEEFLRRNKGPVSIKVQVPNMQDKTEW 720
Query: 656 KLNGQVLVFTLPLTDQVSVIKVKIHEATGMPAGKQKLQYEGIFIKDSNSLAYYNMANGAV 715
KLNGQVLVFTLPLTDQVSVIKVKIHEATGMPAGKQKLQYEGIFIKDSNSLAYYNMANGAV
Sbjct: 721 KLNGQVLVFTLPLTDQVSVIKVKIHEATGMPAGKQKLQYEGIFIKDSNSLAYYNMANGAV 780
Query: 716 IHLALKERGGRKK 728
IHLALKERGGRKK
Sbjct: 781 IHLALKERGGRKK 793
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 95.5 bits (236), Expect = 2e-19
Identities = 134/562 (23%), Positives = 221/562 (39%), Gaps = 77/562 (13%)
Query: 145 KLVEQYTKILIPPKGLFSKLKKEAENPREVLDQVCYRVEWAKFQERERKKEEEEKEKERV 204
K+ E++ +I K L + KKEA V ++ V K + + K+EEE K
Sbjct: 9635 KVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRAVPEEKVLKLKPKREEEPPAKVTE 9694
Query: 205 AYAQIDWHDFVVVETVDFQPNEQGNFPPPTTPEELGARILIQERYEKFGESEEVEMEVES 264
++ + V +E +P T EE ++E EE E E
Sbjct: 9695 FRKRVVKEEKVSIEAPKREPQP---IKEVTIMEEKERAYTLEEEAVSVQREEEYE---EY 9748
Query: 265 DEEDDKQEKAEEPPSQLDQDTQVQDMDEGSDDEEEGQKVPPPPETPMPPPLPPTPDQVIV 324
+E D K+ + EP + DQ + ++ + + EE ++ PE P+P + P P++ +
Sbjct: 9749 EEYDYKEFEEYEPTEEYDQYEEYEEREY--ERYEEHEEYITEPEKPIP--VKPVPEEPVP 9804
Query: 325 RKDYDPKASKPLPPAPAPDEYLVSPITGE-KIPASKMQEHMRIGLLDPRWLEQRDRSIRE 383
K P A K L A P+E + PI + K P K+ E + + E++ R
Sbjct: 9805 TKPKAPPA-KVLKKA-VPEEKVPVPIPKKLKPPPPKVPEEPK------KVFEEKIRISIT 9856
Query: 384 KQSDDEVYAPGLDIESSLKQLAERRTDIFGVEETA-------IGKKIGEEEIQKPEEKVT 436
K+ ++V P + K++ +E A + K++ EE+ EE VT
Sbjct: 9857 KREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELEPEEVAFEEEVVT 9916
Query: 437 WDGHSGSMARTQQAAQANITLQEQIEAIHKAKGLVPEDDTKEKIGPSKPNEIPQQPPPPS 496
++E+ E IH+ + + T+E++ P P ++P+ P P
Sbjct: 9917 H--------------VEEYLVEEEEEYIHEEEEFI----TEEEVVPVIPVKVPEVPRKP- 9957
Query: 497 SATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPII 556
+P P+ VP+ PP + VP +P+ P V L P PP
Sbjct: 9958 ----VPEEKKPVP-VPKKKEAPP-------AKVPEVPKKPEEKVPVLIPKK---EKPPPA 10002
Query: 557 HAPRINVVPMPPSAPPIMAPRP---PPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMED 613
P + P+P P+ P+ PP VP P VP PAP PP + +
Sbjct: 10003 KVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPE 10062
Query: 614 EPTSKKLKTEDSLMPEEEFLRRNKGPVSIKVQVPNMQDKTEWKLNGQVLVFTLPLTDQVS 673
P L+PEE + PV KV+ P K K + LP ++V
Sbjct: 10063 VP--------KKLIPEE----KKPTPVPKKVEAP--PPKVPKKREPVPVPVALPQEEEVL 10108
Query: 674 VIKVKIHEATGMPAGKQKLQYE 695
+ + E +P ++ L E
Sbjct: 10109 FEEEIVPEEEVLPEEEEVLPEE 10130
Score = 87.0 bits (214), Expect = 5e-17
Identities = 169/725 (23%), Positives = 275/725 (37%), Gaps = 112/725 (15%)
Query: 5 PVQAVPPPPPVPTEPKQPTEEEA------------SSKEDSAPSKPVVGIIYPPPEVRNI 52
P + PPP VP PK+P EE +K P KPV P P + +
Sbjct: 9994 PKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKV 10053
Query: 53 VDKTASFVARNGPEFEARIRQNEIN-NPKFNFLNPNDPYHAYYRHKVSEFKEGKAQFVAR 111
A PE ++ E P + P KV + +E VA
Sbjct: 10054 EAPPAKV-----PEVPKKLIPEEKKPTPVPKKVEAPPP-------KVPKKREPVPVPVA- 10100
Query: 112 NGRQFLTQLMQKEQRNYQFDFLRPQHSLFNYFTKLVEQYTKILIPPKGLFSKLKKEAENP 171
L Q+E+ ++ + + P+ + +++ + ++L + + L +E E P
Sbjct: 10101 --------LPQEEEVLFEEEIV-PEEEVLPEEEEVLPEEEEVLPEEEEV---LPEEEEIP 10148
Query: 172 REVLDQVCYRVEWAKFQERERKKEE---EEKEKERVAYAQIDWHDFVVVETVDFQPNEQG 228
E ++V E+ +E +EE E K K V + V + V E+
Sbjct: 10149 PEE-EEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEA 10207
Query: 229 NFPP---PTTPEELGARILIQERYEKFGESEEVEMEVESDEEDDKQEKA-EEPPSQLDQD 284
PP P P+++ + +I + E E VE+ E +EE +E+ EEPPS
Sbjct: 10208 --PPAKVPEVPKKVEEKRIILPKEE---EVLPVEVTEEPEEEPISEEEIPEEPPS----- 10257
Query: 285 TQVQDMDEGSDDE--EEGQKVPPPPETPMP-----PP------LPPTPDQVIVRKDYDPK 331
+++++E + E +K P TP+P PP +P V V+K P
Sbjct: 10258 --IEEVEEVAPPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPP 10315
Query: 332 ASKPLPPAPAPDEYLVSPITGEKIPASK----MQEHMRIGLLDPRWLEQRDRSIREKQSD 387
A P P P++ ++ P E +P +K ++E + + R + +++ +
Sbjct: 10316 AKVPEVPKKVPEKKVLVP-KKEAVPPAKGRTVLEEKVSVAF--------RQEVVVKERLE 10366
Query: 388 DEVYAPGLDIESSLKQLAERRTDIFGVEETAIGKKIGEEEIQKPEEKVTWDGHSGSMART 447
EV +E+ ++++ E + VEE E E + EE + + H
Sbjct: 10367 LEV------VEAEVEEIPEEE-EFHEVEEY-----FEEGEFHEVEEFIKLEQHRVEEEHR 10414
Query: 448 QQAAQANITL--QEQIEAIHKAKGLVPEDDTKEKIGPSK--PNEIPQQPPPPSSATNIPS 503
+ I + E++E K K + EKI P K P ++ + PP+ +P
Sbjct: 10415 VEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEVPK 10474
Query: 504 S--APPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRI 561
VP P +PP T V +P P V P AP P + AP+
Sbjct: 10475 KIVVEEKVRVPEEPRVPP---TKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKE 10531
Query: 562 NVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEP----TS 617
V PP P PP VP A P VP P P PPP + + P
Sbjct: 10532 VVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPE 10591
Query: 618 KKLKTEDSLMPEEEFLRRNKGPVSIKVQVPNMQDKTEWKLNGQVLVFTLPLTDQVSVIKV 677
KK+ PE + K P + K VP + +V +P +V+V +
Sbjct: 10592 KKVPAAPPKKPE---VTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEK 10648
Query: 678 KIHEA 682
K+ EA
Sbjct: 10649 KVPEA 10653
Score = 81.3 bits (199), Expect = 3e-15
Identities = 145/695 (20%), Positives = 255/695 (36%), Gaps = 138/695 (19%)
Query: 5 PVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPPEVRNIVDKTASFVARNG 64
P + PPP VP EPK+P E+ + +P+ + +K V +
Sbjct: 9598 PKKEKVPPPKVPEEPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKE 9657
Query: 65 PEFEARIRQNEINNPKFNFLNPNDPYHAYYRHKVSEFKEGKAQFVARNGRQFLTQLMQKE 124
+AR+ P +P A KV + K + + +F +++++E
Sbjct: 9658 APPKARV--------------PEEPKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVKEE 9703
Query: 125 QRNYQFDFLRPQHSLFNYFTKLVEQYTKILIPPKGLFSKLKKEAENPREVLDQVCYRVEW 184
+ + + PQ T + E+ + + + + ++E E E ++
Sbjct: 9704 KVSIEAPKREPQP--IKEVTIMEEKERAYTLEEEAVSVQREEEYEEYEE--------YDY 9753
Query: 185 AKFQERERKKE-EEEKEKERVAYAQIDWHDFVVVE-----TVDFQPNEQGNFPPPTTPEE 238
+F+E E +E ++ +E E Y + + H+ + E V P E P PT P+
Sbjct: 9754 KEFEEYEPTEEYDQYEEYEEREYERYEEHEEYITEPEKPIPVKPVPEE----PVPTKPKA 9809
Query: 239 LGARILIQERYEKFGESEEVEMEVESDEEDDKQEKAEEPPSQLDQDTQVQDMDEGSDDEE 298
A++L +K E+V + + + + EEP ++ ++ E
Sbjct: 9810 PPAKVL-----KKAVPEEKVPVPIPKKLKPPPPKVPEEPKKVFEEKIRI-----SITKRE 9859
Query: 299 EGQKVPPPPETPMPPPLPPTPDQV-IVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPA 357
+ Q P + PM P ++V + RK+ P P+ P E + E+
Sbjct: 9860 KEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAP----PVRVPEVPKELEPEEVAFEEEVV 9915
Query: 358 SKMQEHMRIGLLDPRWLEQRDRSIREKQS--DDEVYAPGLDI---ESSLKQLAERRTDIF 412
+ ++E++ +E+ + I E++ +E P + + E K + E + +
Sbjct: 9916 THVEEYL---------VEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVP 9966
Query: 413 GVEETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKAKGLVP 472
++ E +KPEEKV L+P
Sbjct: 9967 VPKKKEAPPAKVPEVPKKPEEKV--------------------------------PVLIP 9994
Query: 473 EDDTKEKIGPSKPNEIPQQPPPPSSA-TNIPS--SAPPITSVPRPPTMPPPVRTTVVSAV 529
+ KEK P+K E+P++P P +P APP VP P P P + V A
Sbjct: 9995 K---KEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPP-AKVPEVPKKPVPEKKVPVPAP 10050
Query: 530 PVMPRPPMASVVRLPPGSV-----IAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVP 584
+ PP A V +P + P+P + AP PP P P P P+ +P
Sbjct: 10051 KKVEAPP-AKVPEVPKKLIPEEKKPTPVPKKVEAP-------PPKVPKKREPVPVPVALP 10102
Query: 585 --------TAFVPAPPVAP------------VPAPAPMPPVHPPPPMEDE---PTSKKLK 621
VP V P +P + P P E+E P + +
Sbjct: 10103 QEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVP 10162
Query: 622 TEDSLMPEEEFLRRNKGPVSIKVQVPNMQDKTEWK 656
E+ +PEEE L K V + VP ++ K K
Sbjct: 10163 EEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEK 10197
Score = 74.3 bits (181), Expect = 4e-13
Identities = 109/514 (21%), Positives = 196/514 (38%), Gaps = 75/514 (14%)
Query: 173 EVLDQVCYRVEWAKFQERERKKEEEEKEKERVAYAQIDWHDF--VVVETVDFQPNEQGNF 230
E++D V + E K RKKE + KEKE V + H V +E+ + +P ++
Sbjct: 9026 EIID-VSSKAEEVKIMTITRKKEVQ-KEKEAVYEKKQAVHKEKRVFIESFE-EPYDELEV 9082
Query: 231 PPPTTPEELGARILIQERYEKFGES-EEVEMEVESDEEDDKQEKAEEPPSQLDQDTQVQD 289
P T P E Q YE+ E EE+++E + + ++ +E EE +++ +
Sbjct: 9083 EPYTEPFE-------QPYYEEPDEDYEEIKVEAKKEVHEEWEEDFEEGQEYYERE---EG 9132
Query: 290 MDEGSDDEEEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPP--APAPDEYLV 347
DEG ++ EE + + + + + ++ K +P AP P + +
Sbjct: 9133 YDEGEEEWEEAYQEREVIQV----------QKEVYEESHERKVPAKVPEKKAPPPPKVIK 9182
Query: 348 SPITGEKIPASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSL---KQL 404
P+ + S+ E ++ + + E + + +K S V ++++ K++
Sbjct: 9183 KPVIEKIEKTSRRMEEEKVQVT--KVPEVSKKIVPQKPSRTPVQEEVIEVKVPAVHTKKM 9240
Query: 405 AERRTDIFGVEETAIGKKIGEEEIQKP---EEKVTWDGHSGSMARTQQAAQANITLQEQI 461
+F T + E+QK EEK+ ++ + +++
Sbjct: 9241 VISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKI------------------HVAISKRV 9282
Query: 462 EAIHKAKGLVPEDDTKEKIGP---SKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMP 518
E K L PE E++ P K E P P +P P+ + P P
Sbjct: 9283 EPPPKVPEL-PEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAP 9341
Query: 519 PPVRTTVVSAVPVMPRP-PMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPR 577
P V VP P P+A PP V ++ +I +V +PP P
Sbjct: 9342 PKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPE 9401
Query: 578 PPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDE------PTSKKLK------TEDS 625
P VP P P P P P P P+ +E P +KK ++ +
Sbjct: 9402 IPKKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPEEKVAVPVPVAKKAPPPRAEVSKKT 9461
Query: 626 LMPEEEFLRRNK----GPVSIKVQVPNMQDKTEW 655
++ E+ F+ K P ++V + + EW
Sbjct: 9462 VVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEW 9495
Score = 63.5 bits (153), Expect = 6e-10
Identities = 132/596 (22%), Positives = 211/596 (35%), Gaps = 96/596 (16%)
Query: 147 VEQYTKILIPPKGLFSKLKKEAENPR-EVLDQVCYRVEWAKFQERERKKEEEEKEKERVA 205
V + K +P K + + + E+P EV + V K KK E K A
Sbjct: 10553 VPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEA 10612
Query: 206 YAQIDWHDFVVVETVDFQPNEQGNFPPPTTPEELGARILIQERY--------------EK 251
++ V + V P ++ PP PE ++ + E+ E
Sbjct: 10613 PKEV-----VPEKKVPVPPPKKPEVPPTKVPEV--PKVAVPEKKVPEAIPPKPESPPPEV 10665
Query: 252 FGESEEVEMEVESDEEDDKQEKAEEPPSQLDQDTQVQDMDE----GSDDEEEGQKVPPPP 307
F E EEV +E E ++ E A P + V + E KVP P
Sbjct: 10666 FEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVP 10725
Query: 308 ETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKMQEHMRIG 367
+ +P P V+ +K P A P P E V+ ++P +K+ E +
Sbjct: 10726 KEVVPEKKVPL---VVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKP 10782
Query: 368 LLDPRWL----EQRDRSIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGVEETAIGKKI 423
+L+ + E+ + E + E AP E + E+ + EE +
Sbjct: 10783 VLEEKPAVPVPERAESPPPEVYEEPEEIAP----EEEIAPEEEKPVPVAEEEEPEVPPPA 10838
Query: 424 GEEEIQK--PEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKAKG-------LVPED 474
EE +K PE+KV + + +A E++ K K P++
Sbjct: 10839 VPEEPKKIIPEKKVP-------VIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKE 10891
Query: 475 DTKEKIGPSKP---NEIPQQPPPPSSATNIPSSAPPITSVPR---PPTMPPPVRTTVVSA 528
D KEKI K ++P++P P P P R P P P V+ +
Sbjct: 10892 DVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKS 10951
Query: 529 VPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFV 588
V + + P ++ P + P VP PP P+ P + +
Sbjct: 10952 V--LRKRPEEEEPKVEPKKLEKVKKP--------AVPEPPPPKPVEEVEVPTVTKRERKI 11001
Query: 589 PAP-------PVAPVPAPAPMPPVHP------PPPMEDEPTSKKL--------KTEDSLM 627
P P P P+PAP P P PPP+E EPT K ++
Sbjct: 11002 PEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKAEAKA 11061
Query: 628 PEEEFLRRNKGPV-SIKVQVPNMQDKTEWKL----NGQVLVFTLPLTDQVSVIKVK 678
P+EE + KGP+ + + P+ + KL G+ P T Q+ + +K
Sbjct: 11062 PKEE-AAKPKGPIKGVPKKTPSPIEAERRKLRPGSGGEKPPDEAPFTYQLKAVPLK 11116
Score = 56.2 bits (134), Expect = 1e-07
Identities = 89/429 (20%), Positives = 163/429 (37%), Gaps = 54/429 (12%)
Query: 217 VETVDFQPNEQGNFPPPTTPEELGARILIQERYEKFGESEEVEMEVESDEEDDKQEKAEE 276
V V +P + P P +E A + E +K E++ + V +K E
Sbjct: 9316 VPEVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVA--------KKKEA 9367
Query: 277 PPSQLDQDTQVQDMDEGSDDEEEGQKVPPPPETPMPPPLPPTPDQVIVRKDYD---PKAS 333
PP+++ + + +E + ++ PPP +P P + + RK+ + P
Sbjct: 9368 PPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVPEERKPVPRKEEEVPPPPKV 9427
Query: 334 KPLPPAPAPDEYLVSPI-TGEKIPASKMQEHMRIGLLDPRWLE---------QRDRSIRE 383
LP P P+E + P+ +K P + + + + + R++ QR R
Sbjct: 9428 PALPKKPVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRH 9487
Query: 384 KQSDDEVYAPGLDIESSLKQLAERRTDIFGVEETAIGKKIGEEEIQKPEEKVTWDGHSGS 443
+ S +E ++ + E ++ R + EE A ++ E E+ + E+ +
Sbjct: 9488 EVSAEEEWSYSEEEEGV--SISVYREEEREEEEEA---EVTEYEVMEEPEEYVVEEKLHI 9542
Query: 444 MARTQQAAQANITLQEQIEAIHKAKGLVPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPS 503
+++ +A A +T +++ + + K K +P KI P ++P+ P +P+
Sbjct: 9543 ISKRVEAEPAEVTERQEKKIVLKPK--IPA-----KIEEPPPAKVPEAPKKIVPEKKVPA 9595
Query: 504 SAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLP-PGSVIAPMPPIIHAPRIN 562
P VP PP V VP PP + P P V I ++
Sbjct: 9596 PVPKKEKVP-----PPKVPEEPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEEKVL 9650
Query: 563 VVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKT 622
V AP P A VP P VP + P E+EP +K +
Sbjct: 9651 VAVTKKEAP------------PKARVPEEPKRAVPEEKVL---KLKPKREEEPPAKVTEF 9695
Query: 623 EDSLMPEEE 631
++ EE+
Sbjct: 9696 RKRVVKEEK 9704
Score = 52.8 bits (125), Expect = 1e-06
Identities = 169/768 (22%), Positives = 269/768 (35%), Gaps = 173/768 (22%)
Query: 1 MPAGPVQAVPP--------PP-----PVPTEPKQPTEE-EASSKEDSAPSKPVVG----- 41
+P P++AVPP PP P P E K P + E + K +K VV
Sbjct: 8944 IPTMPIRAVPPEEIPPVVAPPIPLLLPTPEEKKPPPKRIEVTKKAVKKDAKKVVAKPKEM 9003
Query: 42 ------IIYPPPEVRNIVDKTASFVARNGPEFEARI----RQNEINNPKFNFLNPNDPYH 91
+ PPP I K + + E +I R+ E+ K
Sbjct: 9004 TPREEIVKKPPPPTTLIPAKAPEIIDVSSKAEEVKIMTITRKKEVQKEK----------E 9053
Query: 92 AYYRHKVSEFKEGKAQFVARNGRQFLTQLMQKEQRNYQFDFLRPQHSLFNYFTKLVEQYT 151
A Y K + KE K F+ F + E Y F +P Y+ + E Y
Sbjct: 9054 AVYEKKQAVHKE-KRVFI----ESFEEPYDELEVEPYTEPFEQP------YYEEPDEDYE 9102
Query: 152 KILIPPKGLFSKLKKEAENPREVLDQVCYRVEWAKFQERERKKEEEEKEKERVAYAQIDW 211
+I + K ++ +E E E + R E + E E + EE +E+E V Q +
Sbjct: 9103 EIKVEAK---KEVHEEWEEDFEEGQEYYEREEG--YDEGEEEWEEAYQERE-VIQVQKEV 9156
Query: 212 HDFVVVETVDFQPNEQGNFPPP-------------------------TTPEELGARILIQ 246
++ V + E+ PPP T E+ +I+ Q
Sbjct: 9157 YEESHERKVPAKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVSKKIVPQ 9216
Query: 247 ERYEKFGESEEVEMEVE---------SDEEDDKQEKAEEPPSQLDQDTQVQDMDEGSDDE 297
+ + E +E++V S+E+ EE S + Q + + E
Sbjct: 9217 KPSRTPVQEEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKIHV 9276
Query: 298 EEGQKVPPPPETP-----------MPPPLP-----PTPDQVIVRKDYDPKASKPLP---- 337
++V PPP+ P P P+P P P V K P+ KP+P
Sbjct: 9277 AISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKK 9336
Query: 338 -PA-----------PAPDEYLVSPITGEK-IPASKMQEHMRIGLLDPRWLEQRDRSIREK 384
PA P P+E + P+ +K P +K+ E + G++ E++ + ++
Sbjct: 9337 EPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQK-GVVT----EEKITIVTQR 9391
Query: 385 QSDDEVYAPGLDIESSLKQLAERRTDIFGVEET--------AIGKKIGEEEIQKPEEKVT 436
+ P E K++ E R + EE A+ KK PEEKV
Sbjct: 9392 EESPPPAVP----EIPKKKVPEERKPVPRKEEEVPPPPKVPALPKK------PVPEEKVA 9441
Query: 437 WDGHSGSMARTQQAAQANITLQEQ--IEAIHKAKGLVPE--DDTKEKIGPSKPNEIPQQP 492
A +A + T+ E+ A K VP+ + T+ ++ + ++
Sbjct: 9442 VPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEE 9501
Query: 493 PPPSSAT--NIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIA 550
S + V M P V + ++ + V P V
Sbjct: 9502 EGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKR-----VEAEPAEVTE 9556
Query: 551 PMPP-IIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPP 609
I+ P+I P PPP VP A P VPAP P PPP
Sbjct: 9557 RQEKKIVLKPKI----------PAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPP 9606
Query: 610 PMEDEPTSKKLKTEDSLMPEEEFLRRNKGPVSIKVQVPNMQDKTEWKL 657
+ +EP KK E + P+ + + + P+ KV +MQ E K+
Sbjct: 9607 KVPEEP--KKPVPEKKVPPK---VIKMEEPLPAKVTERHMQITQEEKV 9649
Score = 40.8 bits (94), Expect = 0.004
Identities = 37/154 (24%), Positives = 59/154 (38%), Gaps = 14/154 (9%)
Query: 540 VVRLPP-GSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRP--PPMIVPTAFVPAPPVAPV 596
+ RL P G + + I + PP P P P P VP +P P+
Sbjct: 8906 IARLEPRGEARSTAELYLTTKEIKLELKPPDIPDSRVPIPTMPIRAVPPEEIPPVVAPPI 8965
Query: 597 PAPAPMPPVHPPPPMEDEPTSKKLKTE--------DSLMPEEEFLRRNKGPVS-IKVQVP 647
P P P PPP E T K +K + + P EE +++ P + I + P
Sbjct: 8966 PLLLPTPEEKKPPPKRIEVTKKAVKKDAKKVVAKPKEMTPREEIVKKPPPPTTLIPAKAP 9025
Query: 648 NMQDKTEWKLNGQVLVFTLPLTDQVSVIKVKIHE 681
+ D + +V + T+ +V K ++E
Sbjct: 9026 EIIDVS--SKAEEVKIMTITRKKEVQKEKEAVYE 9057
Score = 31.6 bits (70), Expect = 2.7
Identities = 31/118 (26%), Positives = 46/118 (38%), Gaps = 14/118 (11%)
Query: 487 EIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLPPG 546
EI + PP +IP S PI ++P P + V +P++ P + PP
Sbjct: 8927 EIKLELKPP----DIPDSRVPIPTMPIRAVPPEEIPPVVAPPIPLLLPTPEE---KKPPP 8979
Query: 547 SVIAPMPPIIHAPRINVVPMPPSAPP--IMAPRPPPMIVPTAFVP--APPVAPVPAPA 600
I + VV P P + +PPP PT +P AP + V + A
Sbjct: 8980 KRIEVTKKAVKKDAKKVVAKPKEMTPREEIVKKPPP---PTTLIPAKAPEIIDVSSKA 9034
>gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Homo
sapiens]
Length = 406
Score = 80.5 bits (197), Expect = 5e-15
Identities = 58/129 (44%), Positives = 68/129 (52%), Gaps = 27/129 (20%)
Query: 488 IPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGS 547
+PQ P PP +P PP+ PRPP +P P R P+ P PPMA V PPGS
Sbjct: 238 VPQLPRPPV----LP--VPPMP--PRPPMVPMPPRP------PIAPMPPMAPV---PPGS 280
Query: 548 VIAPMPPIIHAPRI-NVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVH 606
+AP+PP PR+ V P PP AP + P PP VPT PP+APVP PM V
Sbjct: 281 RMAPVPP---GPRMAPVPPWPPMAP--VPPWPPMAPVPT----GPPMAPVPPGPPMARVP 331
Query: 607 PPPPMEDEP 615
P PPM P
Sbjct: 332 PGPPMARVP 340
Score = 76.6 bits (187), Expect = 7e-14
Identities = 50/134 (37%), Positives = 62/134 (46%), Gaps = 11/134 (8%)
Query: 484 KPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRL 543
+P +P P PP PPI P PP P P + + PV P P MA V
Sbjct: 243 RPPVLPVPPMPPRPPMVPMPPRPPIA--PMPPMAPVPPGSRM---APVPPGPRMAPVPPW 297
Query: 544 PPGSVIAPMPPIIHAPR-INVVPMPPSAPPIMAPRPPPMI-VPTAFVPAPPVAPVPAPAP 601
PP + + P PP+ P + P+PP P P PPM VP P PP+AP+P P
Sbjct: 298 PPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVP----PGPPMAPLPPGPP 353
Query: 602 MPPVHPPPPMEDEP 615
M P+ P PPM P
Sbjct: 354 MAPLPPGPPMAPLP 367
Score = 73.2 bits (178), Expect = 8e-13
Identities = 47/134 (35%), Positives = 61/134 (45%), Gaps = 10/134 (7%)
Query: 482 PSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVV 541
P +P +P P PP + +P AP P P P V P+ P PP +
Sbjct: 253 PPRPPMVPMPPRPPIAP--MPPMAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWPPMA 310
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAP 601
+P G +AP+PP P V P PP A + P PP +P P PP+AP+P P
Sbjct: 311 PVPTGPPMAPVPP--GPPMARVPPGPPMAR--VPPGPPMAPLP----PGPPMAPLPPGPP 362
Query: 602 MPPVHPPPPMEDEP 615
M P+ P PPM P
Sbjct: 363 MAPLPPGPPMAPLP 376
Score = 62.8 bits (151), Expect = 1e-09
Identities = 53/147 (36%), Positives = 64/147 (43%), Gaps = 39/147 (26%)
Query: 482 PSKPNEIPQQP----PPPSSATNIPSSA--------PPITSVPR-PPTMPPPVRTTVVSA 528
P +P P P PP S +P PP+ VP PP P P T
Sbjct: 262 PPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVP---TGPPM 318
Query: 529 VPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFV 588
PV P PPMA R+PPG +A +PP P + P+PP P MAP P
Sbjct: 319 APVPPGPPMA---RVPPGPPMARVPP---GP--PMAPLPPGPP--MAPLP---------- 358
Query: 589 PAPPVAPVPAPAPMPPVHPPPPMEDEP 615
P PP+AP+P P PP+ P PP P
Sbjct: 359 PGPPMAPLP---PGPPMAPLPPRSHVP 382
Score = 52.4 bits (124), Expect = 1e-06
Identities = 34/86 (39%), Positives = 41/86 (47%), Gaps = 12/86 (13%)
Query: 543 LPPGSVIAPMPPIIHAPRINVVPMPPSAP-------PIMAPRPPPMIVP--TAFVPAPP- 592
L P + +P + P + V PMPP P P +AP PP VP + P PP
Sbjct: 229 LDPALCVHLVPQLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPG 288
Query: 593 --VAPVPAPAPMPPVHPPPPMEDEPT 616
+APVP PM PV P PPM PT
Sbjct: 289 PRMAPVPPWPPMAPVPPWPPMAPVPT 314
Score = 52.0 bits (123), Expect = 2e-06
Identities = 28/90 (31%), Positives = 39/90 (43%), Gaps = 5/90 (5%)
Query: 485 PNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLP 544
P P P PP PP+ VP P M P + P+ P PP + LP
Sbjct: 313 PTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAP-----LPPGPPMAPLPPGPPMAPLP 367
Query: 545 PGSVIAPMPPIIHAPRINVVPMPPSAPPIM 574
PG +AP+PP H P + P+ + P++
Sbjct: 368 PGPPMAPLPPRSHVPHTGLAPVHITWAPVI 397
Score = 33.9 bits (76), Expect = 0.55
Identities = 17/56 (30%), Positives = 24/56 (42%), Gaps = 3/56 (5%)
Query: 568 PSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVH---PPPPMEDEPTSKKL 620
P+ P + P + +P PP+ P P PMPP P PPM P ++
Sbjct: 227 PALDPALCVHLVPQLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRM 282
Score = 30.4 bits (67), Expect = 6.1
Identities = 26/92 (28%), Positives = 34/92 (36%), Gaps = 5/92 (5%)
Query: 471 VPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVP 530
VP + P P PP + P AP P P P P + P
Sbjct: 312 VPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPGPPMAPLPPGPPMAPLPPGPP 371
Query: 531 VMPRPPMASVVRLPPGSVIAPMPPIIHAPRIN 562
+ P PP + V P + +AP+ I AP IN
Sbjct: 372 MAPLPPRSHV----PHTGLAPV-HITWAPVIN 398
Score = 30.0 bits (66), Expect = 7.9
Identities = 29/122 (23%), Positives = 49/122 (40%), Gaps = 12/122 (9%)
Query: 423 IGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKAKGLVPEDD-TKEKIG 481
+GE+ + +EK+T ++ ++ + E +G VP DD +E G
Sbjct: 19 VGEDIEEVNDEKLTVTSLMARGGEDEENTRSKPEYGTEAENNVGTEGSVPSDDQDREGGG 78
Query: 482 PSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVM-------PR 534
+P + QQ PP + PP+ + + PP +TTV P P+
Sbjct: 79 GHEPEQ--QQEEPPLTKPEQQQEEPPLLELKQEQEEPP--QTTVEGPQPAEGPQTAEGPQ 134
Query: 535 PP 536
PP
Sbjct: 135 PP 136
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 78.2 bits (191), Expect = 3e-14
Identities = 45/136 (33%), Positives = 62/136 (45%), Gaps = 10/136 (7%)
Query: 482 PSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMP-----RPP 536
P+ P P PPP + P +APP+ PP PP + T + A+P P + P
Sbjct: 486 PASPPMSPSATPPPQAPP--PLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAP 543
Query: 537 MASVVRLPPGSVIAP---MPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPV 593
+ LP + P PP++ AP + V P PP++P + APR PP P V P +
Sbjct: 544 FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRL 603
Query: 594 APVPAPAPMPPVHPPP 609
AP P PP P
Sbjct: 604 TLALAPGPPPPPSRSP 619
Score = 68.6 bits (166), Expect = 2e-11
Identities = 48/141 (34%), Positives = 64/141 (45%), Gaps = 18/141 (12%)
Query: 482 PSKPNEIPQQPP--PPSSATNIPSS-------APPITSVPRPPTMPP--PVRTTVVSAVP 530
PS P + P PP PP S + P S APP+ P PP PP P T A P
Sbjct: 444 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP 503
Query: 531 VMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVP-TAFVP 589
+ PP+ + + PP + PP + P + +P PP++ P AP P +P +
Sbjct: 504 PLAAPPL-QLAKPPPQA-----PPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLAT 557
Query: 590 APPVAPVPAPAPMPPVHPPPP 610
PP AP AP+ V P PP
Sbjct: 558 PPPQAPPVLAAPLLQVPPSPP 578
Score = 65.9 bits (159), Expect = 1e-10
Identities = 47/142 (33%), Positives = 62/142 (43%), Gaps = 19/142 (13%)
Query: 482 PSKPNEI-------PQQPPP--PSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVM 532
P PN + P PPP P A P ++PP++ PP+ PP VP
Sbjct: 425 PQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPS 484
Query: 533 P--RPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPA 590
P PPM+ PP + PP + AP + + PP APP +A PP +P+
Sbjct: 485 PPASPPMSPSATPPPQA-----PPPLAAPPLQLAKPPPQAPPALA-TPPLQALPSPPASF 538
Query: 591 PPVAPV--PAPAPMPPVHPPPP 610
P AP A PM P+ PPP
Sbjct: 539 PGQAPFSPSASLPMSPLATPPP 560
Score = 63.5 bits (153), Expect = 6e-10
Identities = 40/147 (27%), Positives = 62/147 (42%), Gaps = 35/147 (23%)
Query: 494 PPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPV------MPRPPMASVVRLPPGS 547
PPS PS+ P + ++P PP PP TT + + + +P PP++ + PP +
Sbjct: 342 PPS-----PSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQA 396
Query: 548 VIAPMPPIIHAPRINVVPMPPSAPP-------------------IMAPRPPPMIVPTAFV 588
PP + P + P PP++PP + AP PP P
Sbjct: 397 -----PPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAP 451
Query: 589 PAPPVAPVPAPAPMPPVHPPPPMEDEP 615
+PP +P +P+ PP PP + P
Sbjct: 452 FSPPASPPVSPSATPPSQAPPSLAAPP 478
Score = 62.4 bits (150), Expect = 1e-09
Identities = 43/143 (30%), Positives = 60/143 (41%), Gaps = 24/143 (16%)
Query: 482 PSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPP--PVRTTVVSAVPVMPRPPMAS 539
PS P P PPP + + + PP+ + P PP PP P+ T P+ P A
Sbjct: 382 PSPPLS-PLATPPPQAPPAL--ALPPLQAPPSPPASPPLSPLATP-------SPQAPNAL 431
Query: 540 VVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFV-------PAPP 592
V L P P + AP PP++PP+ PP P + P+PP
Sbjct: 432 AVHLLQAPFSPPPSPPVQAPF-----SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP 486
Query: 593 VAPVPAPAPMPPVHPPPPMEDEP 615
+P +P+ PP PPP+ P
Sbjct: 487 ASPPMSPSATPPPQAPPPLAAPP 509
Score = 60.5 bits (145), Expect = 5e-09
Identities = 44/143 (30%), Positives = 60/143 (41%), Gaps = 18/143 (12%)
Query: 489 PQQPP----PPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRP--------- 535
PQ PP PP A P ++PP++ + P P + P P P
Sbjct: 394 PQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFS 453
Query: 536 PMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAP--RPPPMIVPTAFVPAPPV 593
P AS P + + PP + AP + V P PP A P M+P PPP P + APP+
Sbjct: 454 PPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP-ASPPMSPSATPPPQAPPP--LAAPPL 510
Query: 594 APVPAPAPMPPVHPPPPMEDEPT 616
P PP PP++ P+
Sbjct: 511 QLAKPPPQAPPALATPPLQALPS 533
Score = 58.5 bits (140), Expect = 2e-08
Identities = 58/206 (28%), Positives = 84/206 (40%), Gaps = 33/206 (16%)
Query: 441 SGSMARTQQAAQANITLQEQIEAIHKAKGLVPEDDTKEKIGPSKPNEIPQ-----QPP-- 493
S +A +A + A + L + T + P P+ P PP
Sbjct: 301 SSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPAT 360
Query: 494 PPSSATNI---PSSAPPITSVPRPPTMP---PPVRTTVVSAVPVMPRPPMASVVRLPPGS 547
PPS AT P+ + +P PP P PP + A+P + PP S PP S
Sbjct: 361 PPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPP--SPPASPPLS 418
Query: 548 VIA-PMPPIIHAPRINVVPMP---PSAPPIMAPRPPPM---IVPTAFVP--------APP 592
+A P P +A ++++ P P +PP+ AP PP + P+A P APP
Sbjct: 419 PLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPP 478
Query: 593 VAPVPAPAPMPPVHP---PPPMEDEP 615
+ P+P PP+ P PPP P
Sbjct: 479 LQVPPSPPASPPMSPSATPPPQAPPP 504
Score = 38.5 bits (88), Expect = 0.022
Identities = 86/377 (22%), Positives = 131/377 (34%), Gaps = 65/377 (17%)
Query: 300 GQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLP-----------PAPAPDEYLV- 347
G P PP +P PPP P TP + V KPL P AP
Sbjct: 23 GLLTPRPPGSPRPPP-PVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTR 81
Query: 348 SPITGEKIPASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLK-QLAE 406
S T + PAS+ R P + S V +PG ++ L +
Sbjct: 82 SAGTSSRNPASRPPASGRGERAPPA----------KNTSPGPVSSPGRASGTTRPGPLGQ 131
Query: 407 RRTDIFGVEETAIGKKIGEEE-------IQKPEEKVTWDGHSGSMARTQQAAQANITLQE 459
+ I E A GK + ++ T S +MAR +AA + L
Sbjct: 132 KGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPR 191
Query: 460 QIEAIHKAKGLVPEDDTKEKIGPSKPNEIPQQPPP----PSS--------ATNIPSSAPP 507
+ A+ P + ++ + + + + P PS+ + ++ SSA P
Sbjct: 192 PAPS---ARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP 248
Query: 508 ITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVR----LPPGSVIAP-MPPIIHAPRIN 562
++S R + P T A P P+P +R PP AP + P+ +P
Sbjct: 249 LSSPAR--SGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLAT 306
Query: 563 VVP---MPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPA--------PMPPVHPPPPM 611
P + APP + P + P+AP P+P+ P PP PP
Sbjct: 307 PSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAP-PSPSAPPSLQTLPSPPATPPSQA 365
Query: 612 EDEPTSKKLKTEDSLMP 628
S L+ S +P
Sbjct: 366 TTSLGSPTLQATHSFLP 382
Score = 30.8 bits (68), Expect = 4.6
Identities = 39/170 (22%), Positives = 56/170 (32%), Gaps = 25/170 (14%)
Query: 481 GPSKPNEIPQQPPPPSSATNI--PSSAPPIT-----SVPRPPTMPPPVRTTVVSAVPVMP 533
G + P P+ P S+ T+ P+S PP + + P T P PV + ++ P
Sbjct: 67 GATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP 126
Query: 534 RPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPV 593
P +R+ +A P + A PT P+P +
Sbjct: 127 GPLGQKGLRISAEETVAR----------GKATEAPKRSALSAGARRDTSGPTPGTPSPAM 176
Query: 594 A--------PVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMPEEEFLRR 635
A V P P P P PP E S +E S RR
Sbjct: 177 ARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR 226
Score = 30.4 bits (67), Expect = 6.1
Identities = 17/48 (35%), Positives = 22/48 (45%), Gaps = 2/48 (4%)
Query: 304 PP--PPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSP 349
PP PP +P+ P P P+ + V P + P PP AP SP
Sbjct: 411 PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 458
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 78.2 bits (191), Expect = 3e-14
Identities = 45/136 (33%), Positives = 62/136 (45%), Gaps = 10/136 (7%)
Query: 482 PSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMP-----RPP 536
P+ P P PPP + P +APP+ PP PP + T + A+P P + P
Sbjct: 447 PASPPMSPSATPPPQAPP--PLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAP 504
Query: 537 MASVVRLPPGSVIAP---MPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPV 593
+ LP + P PP++ AP + V P PP++P + APR PP P V P +
Sbjct: 505 FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRL 564
Query: 594 APVPAPAPMPPVHPPP 609
AP P PP P
Sbjct: 565 TLALAPGPPPPPSRSP 580
Score = 73.6 bits (179), Expect = 6e-13
Identities = 54/204 (26%), Positives = 84/204 (41%), Gaps = 39/204 (19%)
Query: 441 SGSMARTQQAAQANITLQEQ--IEAIHKAKGLVPEDDTKEKIGP--SKPNEIPQQPPPPS 496
SG AR A A+ + + ++A+ + P D +GP S P P PPS
Sbjct: 246 SGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPS 305
Query: 497 SATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPV------MPRPPMASVVRLPPGSVIA 550
PS+ P + ++P PP PP TT + + + +P PP++ + PP +
Sbjct: 306 -----PSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQA--- 357
Query: 551 PMPPIIHAPRINVVPMPPSAPP-------------------IMAPRPPPMIVPTAFVPAP 591
PP + P + P PP++PP + AP PP P +P
Sbjct: 358 --PPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP 415
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEP 615
P +P +P+ PP PP + P
Sbjct: 416 PASPPVSPSATPPSQAPPSLAAPP 439
Score = 68.6 bits (166), Expect = 2e-11
Identities = 48/141 (34%), Positives = 64/141 (45%), Gaps = 18/141 (12%)
Query: 482 PSKPNEIPQQPP--PPSSATNIPSS-------APPITSVPRPPTMPP--PVRTTVVSAVP 530
PS P + P PP PP S + P S APP+ P PP PP P T A P
Sbjct: 405 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP 464
Query: 531 VMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVP-TAFVP 589
+ PP+ + + PP + PP + P + +P PP++ P AP P +P +
Sbjct: 465 PLAAPPL-QLAKPPPQA-----PPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLAT 518
Query: 590 APPVAPVPAPAPMPPVHPPPP 610
PP AP AP+ V P PP
Sbjct: 519 PPPQAPPVLAAPLLQVPPSPP 539
Score = 65.9 bits (159), Expect = 1e-10
Identities = 47/142 (33%), Positives = 62/142 (43%), Gaps = 19/142 (13%)
Query: 482 PSKPNEI-------PQQPPP--PSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVM 532
P PN + P PPP P A P ++PP++ PP+ PP VP
Sbjct: 386 PQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPS 445
Query: 533 P--RPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPA 590
P PPM+ PP + PP + AP + + PP APP +A PP +P+
Sbjct: 446 PPASPPMSPSATPPPQA-----PPPLAAPPLQLAKPPPQAPPALA-TPPLQALPSPPASF 499
Query: 591 PPVAPV--PAPAPMPPVHPPPP 610
P AP A PM P+ PPP
Sbjct: 500 PGQAPFSPSASLPMSPLATPPP 521
Score = 60.5 bits (145), Expect = 5e-09
Identities = 44/143 (30%), Positives = 60/143 (41%), Gaps = 18/143 (12%)
Query: 489 PQQPP----PPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRP--------- 535
PQ PP PP A P ++PP++ + P P + P P P
Sbjct: 355 PQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFS 414
Query: 536 PMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAP--RPPPMIVPTAFVPAPPV 593
P AS P + + PP + AP + V P PP A P M+P PPP P + APP+
Sbjct: 415 PPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP-ASPPMSPSATPPPQAPPP--LAAPPL 471
Query: 594 APVPAPAPMPPVHPPPPMEDEPT 616
P PP PP++ P+
Sbjct: 472 QLAKPPPQAPPALATPPLQALPS 494
Score = 54.7 bits (130), Expect = 3e-07
Identities = 46/171 (26%), Positives = 66/171 (38%), Gaps = 25/171 (14%)
Query: 481 GPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASV 540
GPS P+ P PS P RPP + PP R A+ + P+A+
Sbjct: 247 GPSARGT-PRAPAHPSQPK------PKGLQALRPPQVTPP-RKDAAPALGPLSSSPLATP 298
Query: 541 VRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRP---PPMIVPTAFVPAPPVAPVP 597
P S AP P + +P PP+ PP A P + +F+P+PP++P+
Sbjct: 299 SPSAPPSPSAP-------PSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLA 351
Query: 598 APAP-------MPPVHPPPPMEDEPTSKKLKTEDSLMPEEEFLRRNKGPVS 641
P P +PP+ PP P L T P + + P S
Sbjct: 352 TPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS 402
Score = 43.1 bits (100), Expect = 0.001
Identities = 79/351 (22%), Positives = 120/351 (34%), Gaps = 52/351 (14%)
Query: 300 GQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASK 359
G P PP +P PPP P TP + V KPL I G IP S
Sbjct: 23 GLLTPRPPGSPRPPP-PVTPAALRVLGAAGAVGRKPLAER-------AGGIGGATIPESA 74
Query: 360 MQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLK-QLAERRTDIFGVEETA 418
+ P + S V +PG ++ L ++ I E A
Sbjct: 75 PRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVA 134
Query: 419 IGKKIGEEE-------IQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKAKGLV 471
GK + ++ T S +MAR +AA + L + A+
Sbjct: 135 RGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPS---ARPRP 191
Query: 472 PEDDTKEKIGPSKPNEIPQQPPP----PSS--------ATNIPSSAPPITSVPRPPTMPP 519
P + ++ + + + + P PS+ + ++ SSA P++S R + P
Sbjct: 192 PTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPAR--SGPS 249
Query: 520 PVRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPM--PPSAPPIMAPR 577
T A P P+P +R PP + PR + P P S+ P+ P
Sbjct: 250 ARGTPRAPAHPSQPKPKGLQALR----------PPQVTPPRKDAAPALGPLSSSPLATPS 299
Query: 578 PPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P + P+P P P PP PP S L+ S +P
Sbjct: 300 P-------SAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLP 343
Score = 31.2 bits (69), Expect = 3.6
Identities = 30/108 (27%), Positives = 39/108 (36%), Gaps = 14/108 (12%)
Query: 497 SATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPII 556
+A P++ P PRPP P P PV P A++ L + P
Sbjct: 12 AAARTPAARAPGLLTPRPPGSPRP-------PPPVTP----AALRVLGAAGAVGRKPLAE 60
Query: 557 HAPRINVVPMPPSAP---PIMAPRPPPMIVPTAFVPAPPVAPVPAPAP 601
A I +P SAP P RPP PA +P P +P
Sbjct: 61 RAGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSP 108
Score = 30.4 bits (67), Expect = 6.1
Identities = 17/48 (35%), Positives = 22/48 (45%), Gaps = 2/48 (4%)
Query: 304 PP--PPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSP 349
PP PP +P+ P P P+ + V P + P PP AP SP
Sbjct: 372 PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 419
>gi|146134388 YLP motif containing 1 [Homo sapiens]
Length = 2146
Score = 75.9 bits (185), Expect = 1e-13
Identities = 91/387 (23%), Positives = 147/387 (37%), Gaps = 76/387 (19%)
Query: 274 AEEPPSQLDQDTQVQDMDEGSDDEEEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKAS 333
A++ P + ++ V + + + PPP +PPPLPP Q DP+
Sbjct: 323 AKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPLPPEEPQ-----SEDPEED 377
Query: 334 KPLPPAPAPDEYLVSPITGEKIPASKMQEHM--RIGLLDPRWLEQRDRSIREKQSDDEVY 391
L A A+ Q+H R+G +++ + + Q ++
Sbjct: 378 ARLKQLQAA--------------AAHWQQHQQHRVGFQYQGIMQKHTQLQQILQQYQQII 423
Query: 392 APGLDIESSLKQLAERRTDI---------------FGVEETAIGKKIGEEEIQKPEEK-V 435
P I++ + R ++ F + E + ++++Q+ E++
Sbjct: 424 QPPPHIQTMSVDMQLRHYEMQQQQFQHLYQEWEREFQLWEEQLHSYPHKDQLQEYEKQWK 483
Query: 436 TWDGHSGSMARTQQAAQANITLQEQIEAIHKAKG-----------LVPEDDTKEKIGPSK 484
TW GH M TQ LQE++ + K VP +
Sbjct: 484 TWQGH---MKATQSY------LQEKVNSFQNMKNQYMGNMSMPPPFVPYSQMPPPLPTMP 534
Query: 485 PNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASV---- 540
P +P PPP +P++ PP +P PP MPP + T+V P MP P ++S
Sbjct: 535 PPVLPPSLPPPVMPPALPATVPP-PGMP-PPVMPPSLPTSVPP--PGMP-PSLSSAGPPP 589
Query: 541 VRLPPGSVIAPMPPIIHAPRINVVPMPP--SAPPIMAPRPPPMI----VPTAFVPAPPVA 594
V PP A PP++ P ++ PP PP+ + PPP I VP P A
Sbjct: 590 VLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPGVPQGIPPQLTAA 649
Query: 595 PVP----APAPMPPVHPPPPMEDEPTS 617
PVP + + P P P + P S
Sbjct: 650 PVPPASSSQSSQVPEKPRPALLPTPVS 676
Score = 62.0 bits (149), Expect = 2e-09
Identities = 105/437 (24%), Positives = 144/437 (32%), Gaps = 139/437 (31%)
Query: 247 ERYEKFGESEEVEMEVESDEEDDKQEKAEEPPSQLDQDTQVQ-DMDEGSD-DEEEGQKVP 304
ER + E EME + D + D+ + P D+ + D D G DE+E Q
Sbjct: 1269 ERDQDMDEDYNREMERDMDRDVDRISR---PMDMYDRSLDNEWDRDYGRPLDEQESQF-- 1323
Query: 305 PPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKMQEHM 364
+ P PPLPP LPP P D Y
Sbjct: 1324 RERDIPSLPPLPP------------------LPPLPPLDRYR------------------ 1347
Query: 365 RIGLLDPRWLEQRDRS--------------IREKQSDDEVYAPGLD-IESSLKQLAERRT 409
D RW E+R+R IRE + + D + + ER +
Sbjct: 1348 -----DDRWREERNREHGYDRDFRDRGELRIREYPERGDTWREKRDYVPDRMDWERERLS 1402
Query: 410 DIFGVEETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKA-- 467
D + + + E + G S+ Q + Q Q E I KA
Sbjct: 1403 DRWYPSDVDRHSPMAEH-MPSSHHSSEMMGSDASLDSDQGLGGVMVLSQRQHEIILKAAQ 1461
Query: 468 --KGLVPEDDTKEKIGP--SKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRT 523
K L + + +K+ S+P PP S N S RP PPP
Sbjct: 1462 ELKMLREQKEQLQKMKDFGSEPQMADHLPPQESRLQNTSS---------RPGMYPPPGS- 1511
Query: 524 TVVSAVPVMPRPPMASVVRLPPGSVIAPM-PPIIHAPRIN--VVPMPPSAPPIMAPRPPP 580
P PPM PPGS++ P PP + + VP+PP PP P PPP
Sbjct: 1512 -------YRPPPPMGK----PPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLPPPPP 1560
Query: 581 MIVP----------------------------------TAFVPAPPVAP-------VPAP 599
+I P TA +P+ PV P +P P
Sbjct: 1561 VIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPP 1620
Query: 600 AP----MPPVHPPPPME 612
P MPP+ PPP++
Sbjct: 1621 GPVPMGMPPMSKPPPVQ 1637
Score = 41.2 bits (95), Expect = 0.003
Identities = 38/143 (26%), Positives = 52/143 (36%), Gaps = 25/143 (17%)
Query: 484 KPNEIPQQPPPPSSATNIPSSAPPITS-------VPRPPTMPPPVRTTVVSAVPVMPRPP 536
+P+ +P P PP PP+ P PP MPPP + +
Sbjct: 77 QPHHLPPPPLPP----------PPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQ 126
Query: 537 MASVVRL-PPGSVIAPMPPIIHAPRINVVPMPPSA--PPIMAPRPPPMIVPTAFVPAPPV 593
M R PPG V + +P P+PP + PP + PPP P+ + P
Sbjct: 127 MLHHQRDGPPGLVPMELESPPESP-----PVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQ 181
Query: 594 APVPAPAPMPPVHPPPPMEDEPT 616
+P P P PP PT
Sbjct: 182 PYLPPAQPSPSQSPPSQSYLAPT 204
Score = 36.6 bits (83), Expect = 0.085
Identities = 44/183 (24%), Positives = 60/183 (32%), Gaps = 42/183 (22%)
Query: 457 LQEQIEAIHKAKGLVPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPT 516
L Q + +K + L + D + P + P+ PP P P S P + PP
Sbjct: 115 LSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVP------PGSYMPPSQSYMPPP 168
Query: 517 MPPPVRTTVVSAVPVMPRPPMASVVRLPPG-SVIAPMPPII------------------- 556
PPP S+ P +P P S + PP S +AP P
Sbjct: 169 QPPPSYYPPTSSQPYLP-PAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPS 227
Query: 557 -----------HAPRINVVPMPPSAPP----IMAPRPPPMIVPTAFVPAPPVAPVPAPAP 601
H+ + P PPSAPP + P AP P P+
Sbjct: 228 SQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPST 287
Query: 602 MPP 604
M P
Sbjct: 288 MTP 290
Score = 33.9 bits (76), Expect = 0.55
Identities = 46/179 (25%), Positives = 62/179 (34%), Gaps = 42/179 (23%)
Query: 479 KIGPSKPNEIPQQPPPPSSATNIPSSAP-PITSVPRPPTMPPPV--------RTTVVSAV 529
+ G S P PPPP A +P ++P P S P P + +
Sbjct: 7 RYGGSSHYPPPPVPPPPPVA--LPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQL 64
Query: 530 PVMPRPPMASVVR---LPPGSVIAPMPPIIHAPRI-NVVPMPPSAPPIMAPR-------- 577
M + M V++ LPP + P PP++ + P PP PP P
Sbjct: 65 QQMHQKQMQCVLQPHHLPPPPL--PPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQ 122
Query: 578 -----------PPPMIVPTAFVPAPPVAPVPAPAPMPPVH------PPPPMEDEPTSKK 619
PP +VP P PVP + MPP PPP PTS +
Sbjct: 123 YKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQ 181
Score = 32.7 bits (73), Expect = 1.2
Identities = 45/213 (21%), Positives = 81/213 (38%), Gaps = 26/213 (12%)
Query: 172 REVLDQVCYRVEWAKFQERERKKEEEEKEKERVAYAQIDWHDFVVVETVDFQPNEQ--GN 229
RE D V R++W E E+ +R + +D H + + + G+
Sbjct: 1384 REKRDYVPDRMDW-----------ERERLSDRWYPSDVDRHSPMAEHMPSSHHSSEMMGS 1432
Query: 230 FPPPTTPEELGARILIQERYEKF--GESEEVEMEVESDEEDDKQEKAEEPPSQLD----Q 283
+ + LG +++ +R + ++E++M E E+ K + P D Q
Sbjct: 1433 DASLDSDQGLGGVMVLSQRQHEIILKAAQELKMLREQKEQLQKMKDFGSEPQMADHLPPQ 1492
Query: 284 DTQVQDMDE--GSDDEEEGQKVPPP----PETPMPPPLPPTPDQVIVRKDYDPKASKPLP 337
++++Q+ G + PPP P + + P PP V V + P P P
Sbjct: 1493 ESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPP 1552
Query: 338 PAPAPDEYLVSPITGEKIPASKMQEHMRIGLLD 370
P P ++ P T + + E GL D
Sbjct: 1553 PPLPPPPPVIKPQT-SAVEQERWDEDSFYGLWD 1584
Score = 30.8 bits (68), Expect = 4.6
Identities = 54/254 (21%), Positives = 75/254 (29%), Gaps = 19/254 (7%)
Query: 277 PPSQLDQDTQVQDMDEGSDDEEEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPL 336
P L Q Q + + +G P E PP PP P + P S
Sbjct: 111 PGPALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYM----PPSQSYMP 166
Query: 337 PPAPAPDEY---LVSPITGEKIPASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAP 393
PP P P Y P P+ + L S + S + Y P
Sbjct: 167 PPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLP 226
Query: 394 GLDIESSLKQLAERRTDIFGVEETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAA-- 451
S ++ + + Q+P E G QQAA
Sbjct: 227 SSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLE----SGAKNKSTEQQQAAPE 282
Query: 452 --QANITLQEQIEAIHKAKGLVPEDDTKEKIGPSK--PNEIPQQPPPPSSATNIP--SSA 505
+ +T QEQ + ++ L + TK + K P P P +P S
Sbjct: 283 PDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQV 342
Query: 506 PPITSVPRPPTMPP 519
P S PP PP
Sbjct: 343 PESPSSEEPPLPPP 356
Score = 30.8 bits (68), Expect = 4.6
Identities = 18/45 (40%), Positives = 24/45 (53%), Gaps = 3/45 (6%)
Query: 483 SKPNEIPQQP--PPPSSATNIPSSAPPITSVPRPPTMPPPVRTTV 525
S+ IP P PPP ++IP P +P P + PPPV+ TV
Sbjct: 1597 SETAAIPSAPVLPPPPVHSSIPPPGPVPMGMP-PMSKPPPVQQTV 1640
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 75.1 bits (183), Expect = 2e-13
Identities = 49/129 (37%), Positives = 62/129 (48%), Gaps = 16/129 (12%)
Query: 492 PPPPSSATNIPSSAP-PITSVPRPPTMP----PPVRTTVVSAVPVMPRPPMASVVRLP-- 544
PPPP IP P P +P PP +P PP + +P P P A + P
Sbjct: 1076 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1135
Query: 545 PGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAP---VPAPAP 601
PG+ I P PP+ PR+ +P PP P P PPP+ P A +P PP P +P P P
Sbjct: 1136 PGAGIPPPPPL---PRVG-IPPPPPLPGAGIPPPPPL--PGAGIPPPPPLPGVGIPPPPP 1189
Query: 602 MPPVHPPPP 610
+P V PPP
Sbjct: 1190 LPGVGIPPP 1198
Score = 74.3 bits (181), Expect = 4e-13
Identities = 47/139 (33%), Positives = 65/139 (46%), Gaps = 22/139 (15%)
Query: 482 PSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVV 541
P+ P+ QPPP +P PP+ PP PPP + ++P PP+
Sbjct: 889 PTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPP--PPP-----LPGAGILPLPPLPGAG 941
Query: 542 RLP----PGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAP-- 595
P PG+ I P PP+ A +P+PP P P PPP+ P A +P PP P
Sbjct: 942 IPPPPPLPGAAIPPPPPLPGAG----IPLPPPLPGAGIPPPPPL--PGAGIPPPPPLPGA 995
Query: 596 -VPAPAPMP--PVHPPPPM 611
+P P P+P + PPPP+
Sbjct: 996 GIPPPPPLPGAGIPPPPPL 1014
Score = 73.2 bits (178), Expect = 8e-13
Identities = 48/132 (36%), Positives = 63/132 (47%), Gaps = 18/132 (13%)
Query: 492 PPPPSSATNIPSSAP-PITSVPRPPTMP----PPVRTTVVSAVPVMPRPPMASVVRLP-- 544
PPPP IP P P +P PP +P PP + +P P P A + P
Sbjct: 1021 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1080
Query: 545 PGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAP---VPAPAP 601
PG+ I P PP+ A +P PP P + P PPP+ P A +P PP P +P P P
Sbjct: 1081 PGAGIPPPPPLPGAG----IPPPPPLPGVGIPPPPPL--PGAGIPPPPPLPGAGIPPPPP 1134
Query: 602 MP--PVHPPPPM 611
+P + PPPP+
Sbjct: 1135 LPGAGIPPPPPL 1146
Score = 72.8 bits (177), Expect = 1e-12
Identities = 45/130 (34%), Positives = 62/130 (47%), Gaps = 17/130 (13%)
Query: 493 PPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLP------PG 546
PPP T SS P + VP PP P + + + + PP+ LP PG
Sbjct: 858 PPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPG 917
Query: 547 SVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAP---VPAPAPMP 603
+ I P PP+ P ++P+PP P P PPP+ P A +P PP P +P P P+P
Sbjct: 918 AGIPPPPPL---PGAGILPLPP-LPGAGIPPPPPL--PGAAIPPPPPLPGAGIPLPPPLP 971
Query: 604 --PVHPPPPM 611
+ PPPP+
Sbjct: 972 GAGIPPPPPL 981
Score = 72.8 bits (177), Expect = 1e-12
Identities = 48/129 (37%), Positives = 60/129 (46%), Gaps = 16/129 (12%)
Query: 492 PPPPSSATNIPSSAP-PITSVPRPPTMP----PPVRTTVVSAVPVMPRPPMASVVRLP-- 544
PPPP IP P P +P PP +P PP +P P P A + P
Sbjct: 1065 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPL 1124
Query: 545 PGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAP---VPAPAP 601
PG+ I P PP+ A +P PP P + P PPP+ P A +P PP P +P P P
Sbjct: 1125 PGAGIPPPPPLPGAG----IPPPPPLPRVGIPPPPPL--PGAGIPPPPPLPGAGIPPPPP 1178
Query: 602 MPPVHPPPP 610
+P V PPP
Sbjct: 1179 LPGVGIPPP 1187
Score = 72.4 bits (176), Expect = 1e-12
Identities = 48/129 (37%), Positives = 61/129 (47%), Gaps = 16/129 (12%)
Query: 492 PPPPSSATNIPSSAP-PITSVPRPPTMP----PPVRTTVVSAVPVMPRPPMASVVRLP-- 544
PPPP IP P P +P PP +P PP + +P P P A + P
Sbjct: 1032 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1091
Query: 545 PGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAP---VPAPAP 601
PG+ I P PP+ P + +P PP P P PPP+ P A +P PP P +P P P
Sbjct: 1092 PGAGIPPPPPL---PGVG-IPPPPPLPGAGIPPPPPL--PGAGIPPPPPLPGAGIPPPPP 1145
Query: 602 MPPVHPPPP 610
+P V PPP
Sbjct: 1146 LPRVGIPPP 1154
Score = 70.9 bits (172), Expect = 4e-12
Identities = 48/153 (31%), Positives = 69/153 (45%), Gaps = 39/153 (25%)
Query: 492 PPPPSSATNIPSSAPPITSVPRPPTM------PPPVRTTVVSAVPVMPRPPMASVVRLPP 545
PPPP +P+ P T++P+PP + PPP + +P P P A ++ LPP
Sbjct: 879 PPPPLPGMTVPTL--PSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPP 936
Query: 546 -------------GSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMI---------V 583
G+ I P PP+ A +P+PP P P PPP+ +
Sbjct: 937 LPGAGIPPPPPLPGAAIPPPPPLPGAG----IPLPPPLPGAGIPPPPPLPGAGIPPPPPL 992
Query: 584 PTAFVPAPPVAP---VPAPAPMP--PVHPPPPM 611
P A +P PP P +P P P+P + PPPP+
Sbjct: 993 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1025
Score = 70.9 bits (172), Expect = 4e-12
Identities = 48/132 (36%), Positives = 62/132 (46%), Gaps = 18/132 (13%)
Query: 492 PPPPSSATNIPSSAP-PITSVPRPPTMP----PPVRTTVVSAVPVMPRPPMASVVRLPP- 545
PPPP IP P P +P PP +P PP + +P P P A + PP
Sbjct: 944 PPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1003
Query: 546 -GSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAP---VPAPAP 601
G+ I P PP+ A +P PP P P PPP+ P A +P PP P +P P P
Sbjct: 1004 PGAGIPPPPPLPGAG----IPPPPPLPGAGIPPPPPL--PGAGIPPPPPLPGAGIPPPPP 1057
Query: 602 MP--PVHPPPPM 611
+P + PPPP+
Sbjct: 1058 LPGAGIPPPPPL 1069
Score = 70.5 bits (171), Expect = 5e-12
Identities = 50/153 (32%), Positives = 67/153 (43%), Gaps = 29/153 (18%)
Query: 482 PSKPNEIPQQPPPPSSATNIPSSAP------------PITSVPRPPTMP----PPVRTTV 525
P + E+ PPPP IP P P +P PP +P PP
Sbjct: 901 PLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLP 960
Query: 526 VSAVPVMPRPPMASVVRLPP--GSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIV 583
+ +P+ P P A + PP G+ I P PP+ A +P PP P P PPP+
Sbjct: 961 GAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG----IPPPPPLPGAGIPPPPPL-- 1014
Query: 584 PTAFVPAPPVAP---VPAPAPMP--PVHPPPPM 611
P A +P PP P +P P P+P + PPPP+
Sbjct: 1015 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1047
Score = 70.5 bits (171), Expect = 5e-12
Identities = 48/132 (36%), Positives = 61/132 (46%), Gaps = 18/132 (13%)
Query: 492 PPPPSSATNIPSSAP-PITSVPRPPTMP----PPVRTTVVSAVPVMPRPPMASVVRLP-- 544
PPPP IP P P +P PP +P PP + +P P P A + P
Sbjct: 1043 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1102
Query: 545 PGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAP---VPAPAP 601
PG I P PP+ A +P PP P P PPP+ P A +P PP P +P P P
Sbjct: 1103 PGVGIPPPPPLPGAG----IPPPPPLPGAGIPPPPPL--PGAGIPPPPPLPRVGIPPPPP 1156
Query: 602 MP--PVHPPPPM 611
+P + PPPP+
Sbjct: 1157 LPGAGIPPPPPL 1168
Score = 70.1 bits (170), Expect = 7e-12
Identities = 47/132 (35%), Positives = 61/132 (46%), Gaps = 18/132 (13%)
Query: 492 PPPPSSATNIPSSAP-PITSVPRPPTMP----PPVRTTVVSAVPVMPRPPMASVVRLPP- 545
PPPP IP P P +P PP +P PP + +P P P A + PP
Sbjct: 1010 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1069
Query: 546 -GSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAP---VPAPAP 601
G+ I P PP+ A +P PP P P PPP+ P +P PP P +P P P
Sbjct: 1070 PGAGIPPPPPLPGAG----IPPPPPLPGAGIPPPPPL--PGVGIPPPPPLPGAGIPPPPP 1123
Query: 602 MP--PVHPPPPM 611
+P + PPPP+
Sbjct: 1124 LPGAGIPPPPPL 1135
Score = 68.2 bits (165), Expect = 3e-11
Identities = 48/137 (35%), Positives = 65/137 (47%), Gaps = 17/137 (12%)
Query: 482 PSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P +P P +T IP P + PP PPP+ + +P P P A ++
Sbjct: 877 PPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPP-PPPLPG---AGIPPPPPLPGAGIL 932
Query: 542 RLP--PGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAP---V 596
LP PG+ I P PP+ A +P PP P P PPP+ P A +P PP P +
Sbjct: 933 PLPPLPGAGIPPPPPLPGA----AIPPPPPLPGAGIPLPPPL--PGAGIPPPPPLPGAGI 986
Query: 597 PAPAPMP--PVHPPPPM 611
P P P+P + PPPP+
Sbjct: 987 PPPPPLPGAGIPPPPPL 1003
Score = 65.5 bits (158), Expect = 2e-10
Identities = 53/167 (31%), Positives = 70/167 (41%), Gaps = 21/167 (12%)
Query: 471 VPEDDTKEKIGPSKPNEIPQQ---PPPPSSATNIPSSAP-PITSVPRPPTMP----PPVR 522
+P +G P +P PPPP IP P P +P PP +P PP
Sbjct: 1096 IPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPP 1155
Query: 523 TTVVSAVPVMPRPPMASVVRLPP--GSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPP 580
+ +P P P A + PP G I P PP+ P + + P PP P P PPP
Sbjct: 1156 PLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPL---PGVGIPP-PPPLPGAGIPPPPP 1211
Query: 581 MIVPTAFVPAPPVAPVPAPA---PMPPVHP--PPPMEDEPTSKKLKT 622
+ P +P P P+P P P PP+ P PP+ + S L T
Sbjct: 1212 L--PGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPT 1256
Score = 56.2 bits (134), Expect = 1e-07
Identities = 42/161 (26%), Positives = 66/161 (40%), Gaps = 36/161 (22%)
Query: 484 KPNEIPQQPPPP-----SSATNIPSSAPPIT---------------------SVPRPPTM 517
+P + QPPPP S+ P S PP + ++P PP +
Sbjct: 802 QPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPL 861
Query: 518 PPPVRTTVVSAVPVMPRPPM---ASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIM 574
P ++ + + ++P PP V P + I PP+ ++P PP P
Sbjct: 862 PCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPL---QGTEMLPPPPPPLPGA 918
Query: 575 APRPPPMIVPTAFVPAPPV--APVPAPAPMP--PVHPPPPM 611
PPP + +P PP+ A +P P P+P + PPPP+
Sbjct: 919 GIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPL 959
Score = 55.8 bits (133), Expect = 1e-07
Identities = 44/146 (30%), Positives = 60/146 (41%), Gaps = 23/146 (15%)
Query: 471 VPEDDTKEKIGPSKPNEIPQQ---PPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVS 527
+P ++G P +P PPPP IP PP+ V PP PPP+
Sbjct: 1140 IPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPP-PPLPGVGIPP--PPPL-----P 1191
Query: 528 AVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINV--VPMPPSAPPIMAPRPPPMIVPT 585
V + P PP+ PG+ I P PP+ P + + P PP PP PPP++ +
Sbjct: 1192 GVGIPPPPPL-------PGAGIPPPPPL---PGMGIPPAPAPPLPPPGTGIPPPPLLPVS 1241
Query: 586 AFVPAPPVAPVPAPAPMPPVHPPPPM 611
P V P P PPP+
Sbjct: 1242 GPPLLPQVGSSTLPTPQVCGFLPPPL 1267
Score = 33.9 bits (76), Expect = 0.55
Identities = 21/62 (33%), Positives = 27/62 (43%), Gaps = 14/62 (22%)
Query: 299 EGQKVPPPPETPMP----PPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEK 354
+G ++ PPP P+P PP PP P I+ PLPP P P+ G
Sbjct: 903 QGTEMLPPPPPPLPGAGIPPPPPLPGAGIL----------PLPPLPGAGIPPPPPLPGAA 952
Query: 355 IP 356
IP
Sbjct: 953 IP 954
Score = 32.7 bits (73), Expect = 1.2
Identities = 23/60 (38%), Positives = 26/60 (43%), Gaps = 3/60 (5%)
Query: 300 GQKVPPPPETPMPP--PLPPTPDQVIVRKDYDPKAS-KPLPPAPAPDEYLVSPITGEKIP 356
G +PPPP P PLPP P I P A+ P PP P L P+ G IP
Sbjct: 917 GAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIP 976
Score = 32.3 bits (72), Expect = 1.6
Identities = 17/46 (36%), Positives = 20/46 (43%)
Query: 2 PAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPP 47
P P +PPPPP+P P + P P VGI PPP
Sbjct: 1067 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPP 1112
Score = 32.3 bits (72), Expect = 1.6
Identities = 17/46 (36%), Positives = 20/46 (43%)
Query: 2 PAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPP 47
P P +PPPPP+P P + P P VGI PPP
Sbjct: 1111 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPP 1156
Score = 32.3 bits (72), Expect = 1.6
Identities = 25/63 (39%), Positives = 27/63 (42%), Gaps = 11/63 (17%)
Query: 300 GQKVPPPPETP---MPPPLPPTPDQVIVRKDYDPKASKPLPP-------APAPDEYLVSP 349
G +PPPP P +PPP PP P I P A P PP PAP L P
Sbjct: 1170 GAGIPPPPPLPGVGIPPP-PPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPP 1228
Query: 350 ITG 352
TG
Sbjct: 1229 GTG 1231
Score = 32.0 bits (71), Expect = 2.1
Identities = 24/62 (38%), Positives = 28/62 (45%), Gaps = 7/62 (11%)
Query: 300 GQKVPPPPETP---MPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYL--VSPITGEK 354
G +PPPP P +PPP PP P I P A P PP P P + P+ G
Sbjct: 939 GAGIPPPPPLPGAAIPPP-PPLPGAGIPLPPPLPGAGIP-PPPPLPGAGIPPPPPLPGAG 996
Query: 355 IP 356
IP
Sbjct: 997 IP 998
Score = 32.0 bits (71), Expect = 2.1
Identities = 24/62 (38%), Positives = 28/62 (45%), Gaps = 7/62 (11%)
Query: 300 GQKVPPPPETP---MPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYL--VSPITGEK 354
G +PPPP P +PPP PP P I P A P PP P P + P+ G
Sbjct: 983 GAGIPPPPPLPGAGIPPP-PPLPGAGIPPPPPLPGAGIP-PPPPLPGAGIPPPPPLPGAG 1040
Query: 355 IP 356
IP
Sbjct: 1041 IP 1042
Score = 32.0 bits (71), Expect = 2.1
Identities = 24/62 (38%), Positives = 28/62 (45%), Gaps = 7/62 (11%)
Query: 300 GQKVPPPPETP---MPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYL--VSPITGEK 354
G +PPPP P +PPP PP P I P A P PP P P + P+ G
Sbjct: 1005 GAGIPPPPPLPGAGIPPP-PPLPGAGIPPPPPLPGAGIP-PPPPLPGAGIPPPPPLPGAG 1062
Query: 355 IP 356
IP
Sbjct: 1063 IP 1064
Score = 32.0 bits (71), Expect = 2.1
Identities = 24/62 (38%), Positives = 28/62 (45%), Gaps = 7/62 (11%)
Query: 300 GQKVPPPPETP---MPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYL--VSPITGEK 354
G +PPPP P +PPP PP P I P A P PP P P + P+ G
Sbjct: 1027 GAGIPPPPPLPGAGIPPP-PPLPGAGIPPPPPLPGAGIP-PPPPLPGAGIPPPPPLPGAG 1084
Query: 355 IP 356
IP
Sbjct: 1085 IP 1086
Score = 32.0 bits (71), Expect = 2.1
Identities = 17/46 (36%), Positives = 20/46 (43%)
Query: 2 PAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPP 47
P P +PPPPP+P P + P P VGI PPP
Sbjct: 1144 PPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPP 1189
Score = 31.6 bits (70), Expect = 2.7
Identities = 16/47 (34%), Positives = 20/47 (42%)
Query: 1 MPAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPP 47
+P P +PPPPP+P P + P P GI PPP
Sbjct: 934 LPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPP 980
Score = 31.6 bits (70), Expect = 2.7
Identities = 24/62 (38%), Positives = 28/62 (45%), Gaps = 7/62 (11%)
Query: 300 GQKVPPPPETP---MPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYL--VSPITGEK 354
G +PPPP P +PPP PP P I P A P PP P P + P+ G
Sbjct: 1049 GAGIPPPPPLPGAGIPPP-PPLPGAGIPPPPPLPGAGIP-PPPPLPGAGIPPPPPLPGVG 1106
Query: 355 IP 356
IP
Sbjct: 1107 IP 1108
Score = 31.6 bits (70), Expect = 2.7
Identities = 24/62 (38%), Positives = 28/62 (45%), Gaps = 7/62 (11%)
Query: 300 GQKVPPPPETP---MPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYL--VSPITGEK 354
G +PPPP P +PPP PP P I P A P PP P P + P+ G
Sbjct: 1082 GAGIPPPPPLPGAGIPPP-PPLPGVGIPPPPPLPGAGIP-PPPPLPGAGIPPPPPLPGAG 1139
Query: 355 IP 356
IP
Sbjct: 1140 IP 1141
Score = 31.2 bits (69), Expect = 3.6
Identities = 22/56 (39%), Positives = 26/56 (46%), Gaps = 4/56 (7%)
Query: 303 VPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYL--VSPITGEKIP 356
+PP P +PPP PP P I P A PLPP P P + P+ G IP
Sbjct: 934 LPPLPGAGIPPP-PPLPGAAIPPPPPLPGAGIPLPP-PLPGAGIPPPPPLPGAGIP 987
Score = 31.2 bits (69), Expect = 3.6
Identities = 24/62 (38%), Positives = 28/62 (45%), Gaps = 7/62 (11%)
Query: 300 GQKVPPPPETP---MPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYL--VSPITGEK 354
G +PPPP P +PPP PP P I P A P PP P P + P+ G
Sbjct: 1137 GAGIPPPPPLPRVGIPPP-PPLPGAGIPPPPPLPGAGIP-PPPPLPGVGIPPPPPLPGVG 1194
Query: 355 IP 356
IP
Sbjct: 1195 IP 1196
Score = 31.2 bits (69), Expect = 3.6
Identities = 17/46 (36%), Positives = 19/46 (41%)
Query: 2 PAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPP 47
P P +PPPPP+P P P P VGI PPP
Sbjct: 1155 PPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPP 1200
Score = 31.2 bits (69), Expect = 3.6
Identities = 16/54 (29%), Positives = 23/54 (42%), Gaps = 3/54 (5%)
Query: 300 GQKVPPPPETPMPPP---LPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPI 350
G +PP P P+PPP +PP P + P+ P P +L P+
Sbjct: 1214 GMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPL 1267
Score = 30.8 bits (68), Expect = 4.6
Identities = 25/72 (34%), Positives = 29/72 (40%), Gaps = 16/72 (22%)
Query: 300 GQKVPPPPETP-----MPPPLP--------PTPDQVIVRKDYDPKASKPLPPAPAPDEYL 346
G +PPPP P +PPPLP P P I P A P PP P P +
Sbjct: 950 GAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP-PPPPLPGAGI 1008
Query: 347 --VSPITGEKIP 356
P+ G IP
Sbjct: 1009 PPPPPLPGAGIP 1020
Score = 30.8 bits (68), Expect = 4.6
Identities = 16/46 (34%), Positives = 19/46 (41%)
Query: 2 PAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPP 47
P P +PPPPP+P P + P P GI PPP
Sbjct: 968 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1013
Score = 30.8 bits (68), Expect = 4.6
Identities = 16/46 (34%), Positives = 19/46 (41%)
Query: 2 PAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPP 47
P P +PPPPP+P P + P P GI PPP
Sbjct: 1001 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1046
Score = 30.8 bits (68), Expect = 4.6
Identities = 16/46 (34%), Positives = 19/46 (41%)
Query: 2 PAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPP 47
P P +PPPPP+P P + P P GI PPP
Sbjct: 1034 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1079
Score = 30.8 bits (68), Expect = 4.6
Identities = 24/62 (38%), Positives = 28/62 (45%), Gaps = 7/62 (11%)
Query: 300 GQKVPPPPETP---MPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYL--VSPITGEK 354
G +PPPP P +PPP PP P I P A P PP P P + P+ G
Sbjct: 1104 GVGIPPPPPLPGAGIPPP-PPLPGAGIPPPPPLPGAGIP-PPPPLPRVGIPPPPPLPGAG 1161
Query: 355 IP 356
IP
Sbjct: 1162 IP 1163
Score = 30.4 bits (67), Expect = 6.1
Identities = 24/101 (23%), Positives = 34/101 (33%), Gaps = 19/101 (18%)
Query: 272 EKAEEPPSQLDQDTQVQDMDEGSDDEEEGQKVPPPPETP-------------MPPPLPPT 318
+ +PP + + Q S + +P PP P +PPP PP
Sbjct: 824 QPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPL 883
Query: 319 PDQVIVRKDYDPKASKPLPPAPAPDEYL---VSPITGEKIP 356
P + P + P PP E L P+ G IP
Sbjct: 884 PGMTVPTL---PSTAIPQPPPLQGTEMLPPPPPPLPGAGIP 921
Score = 30.4 bits (67), Expect = 6.1
Identities = 23/62 (37%), Positives = 27/62 (43%), Gaps = 7/62 (11%)
Query: 300 GQKVPPPPETP---MPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYL--VSPITGEK 354
G +PPPP P +PPP PP P I P P PP P P + P+ G
Sbjct: 1071 GAGIPPPPPLPGAGIPPP-PPLPGAGIPPPPPLPGVGIP-PPPPLPGAGIPPPPPLPGAG 1128
Query: 355 IP 356
IP
Sbjct: 1129 IP 1130
Score = 30.4 bits (67), Expect = 6.1
Identities = 16/46 (34%), Positives = 19/46 (41%)
Query: 2 PAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPP 47
P P +PPPPP+P P + P P GI PPP
Sbjct: 1100 PPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1145
>gi|23111062 splicing factor, arginine/serine-rich 8 [Homo sapiens]
Length = 951
Score = 74.7 bits (182), Expect = 3e-13
Identities = 45/106 (42%), Positives = 56/106 (52%), Gaps = 9/106 (8%)
Query: 6 VQAVPPPPPVPTEPKQPTEEEASSKEDSAPSK-----PVVGIIYPPPEVRNIVDKTASFV 60
V PPPP T PT E SS S + PV II PPP+V+ ++DK A +V
Sbjct: 408 VTTTAPPPPGTTPLPPPTTAETSSGATSTTTTTSALAPVAAIIPPPPDVQPVIDKLAEYV 467
Query: 61 ARNGPEFEARIRQNEINNPKFNFLNPNDPYHAYYRHKVSEF--KEG 104
ARNG +FE +R N+ +F FL P Y+AYY K F KEG
Sbjct: 468 ARNGLKFETSVRAK--NDQRFEFLQPWHQYNAYYEFKKQFFLQKEG 511
Score = 56.2 bits (134), Expect = 1e-07
Identities = 35/113 (30%), Positives = 56/113 (49%), Gaps = 18/113 (15%)
Query: 18 EPKQPTEEEASSK-----------EDSAPSKPVVGIIYP-----PP--EVRNIVDKTASF 59
+P +PTEEE SK E+ P +G+ P PP ++ I+++TASF
Sbjct: 159 DPSEPTEEEEPSKQREKNEAENLEENEEPFVAPLGLSVPSDVELPPTAKMHAIIERTASF 218
Query: 60 VARNGPEFEARIRQNEINNPKFNFLNPNDPYHAYYRHKVSEFKEGKAQFVARN 112
V R G +FE ++ + N +F+FL + + YY+ KEG+ +A N
Sbjct: 219 VCRQGAQFEIMLKAKQARNSQFDFLRFDHYLNPYYKFIQKAMKEGRYTVLAEN 271
Score = 39.3 bits (90), Expect = 0.013
Identities = 43/165 (26%), Positives = 58/165 (35%), Gaps = 34/165 (20%)
Query: 503 SSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSV-IAPMPP------- 554
SS P + P P V T S V M S LP G+ +AP PP
Sbjct: 337 SSTPTPHNADGAPVQPSQVEYTADSTVAAM----YYSYYMLPDGTYCLAPPPPGIDVTTY 392
Query: 555 ---------IIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPV 605
+ ++P + PP P P PPP T+ A AP+ +
Sbjct: 393 YSTLPAGVTVSNSPGVTTTAPPP---PGTTPLPPPTTAETSSGATSTTTTTSALAPVAAI 449
Query: 606 HPPPPMEDEPTSKKLKTEDSLMPEEEFLRRNKGPVSIKVQVPNMQ 650
PPPP + +P KL E++ RN V+ N Q
Sbjct: 450 IPPPP-DVQPVIDKL---------AEYVARNGLKFETSVRAKNDQ 484
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 74.3 bits (181), Expect = 4e-13
Identities = 49/142 (34%), Positives = 65/142 (45%), Gaps = 18/142 (12%)
Query: 482 PSKPNEI-------PQQPPP--PSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVM 532
P PN + P PPP P A P ++PP++ PP+ PP VP
Sbjct: 650 PQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPS 709
Query: 533 P--RPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIM-APRPPPMIVPTAFVP 589
P PPM+ PP + PP + AP + V P PP++PP+ + PPP + P P
Sbjct: 710 PPASPPMSPSATPPPQA-----PPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAP 764
Query: 590 APPVAP-VPAPAPMPPVHPPPP 610
V P PA PM P+ PPP
Sbjct: 765 PLQVPPSPPASLPMSPLAKPPP 786
Score = 69.7 bits (169), Expect = 9e-12
Identities = 45/147 (30%), Positives = 65/147 (44%), Gaps = 19/147 (12%)
Query: 482 PSKPNEIPQQPPPP-------SSATNIPSSAP---PITSVPRPPTMPPP-VRTTVVSAVP 530
P+ P P PPP + +P S P P++ + +PP PP + T + A+P
Sbjct: 742 PASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALP 801
Query: 531 VMP-----RPPMASVVRLPPGSVIAP---MPPIIHAPRINVVPMPPSAPPIMAPRPPPMI 582
P + P + LP + P PP++ AP + V P PP++P + APR PP
Sbjct: 802 SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTP 861
Query: 583 VPTAFVPAPPVAPVPAPAPMPPVHPPP 609
P V P + AP P PP P
Sbjct: 862 GPDTSVSGPRLTLALAPGPPPPPSRSP 888
Score = 68.9 bits (167), Expect = 2e-11
Identities = 52/164 (31%), Positives = 72/164 (43%), Gaps = 38/164 (23%)
Query: 482 PSKPNEIPQQPP--PPSSATNIPSS-------APPITSVPRPPTMPP--PVRTTVVSAVP 530
PS P + P PP PP S + P S APP+ P PP PP P T A P
Sbjct: 669 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP 728
Query: 531 VMPRPPMASVVRLPPGSVIAP-------MPPIIHAPRINVVPMPPSAPPIMAP--RPPPM 581
+ PP+ P ++P +PP++ AP + V P PP++ P M+P +PPP
Sbjct: 729 PLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLP-MSPLAKPPPQ 787
Query: 582 IVPTAFVPAPPVAPVPAP---------------APMPPVHPPPP 610
P + PP+ +P+P PM P+ PPP
Sbjct: 788 APPA--LATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPP 829
Score = 68.9 bits (167), Expect = 2e-11
Identities = 46/140 (32%), Positives = 65/140 (46%), Gaps = 14/140 (10%)
Query: 482 PSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPP--PVRTTVVSAVPVMPRPPMAS 539
P+ P P PPP + P +APP+ P PP PP P T P++ PP+
Sbjct: 711 PASPPMSPSATPPPQAPP--PLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPL-Q 767
Query: 540 VVRLPPGSV-IAPM-------PPIIHAPRINVVPMPPSAPPIMAPRPPPMIVP-TAFVPA 590
V PP S+ ++P+ PP + P + +P PP++ P AP P +P +
Sbjct: 768 VPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP 827
Query: 591 PPVAPVPAPAPMPPVHPPPP 610
PP AP AP+ V P PP
Sbjct: 828 PPQAPPVLAAPLLQVPPSPP 847
Score = 65.9 bits (159), Expect = 1e-10
Identities = 83/395 (21%), Positives = 133/395 (33%), Gaps = 82/395 (20%)
Query: 299 EGQKVPPPPE--TPMPPPLPPTPDQVIVRKDYDPKASKP-----------LPPAPAPDEY 345
+ + VPPP TP+P LPP+P P S P PP+ AP
Sbjct: 313 KARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSM 372
Query: 346 LVSPITG----EKIPASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSL 401
P+ + IP ++ + L ++ Q+ + +P L S
Sbjct: 373 TTPPMQAPPSLQTIPPIQVPHSLTSPSLQA---PPSPLALSSLQATTSLGSPTLQATHSF 429
Query: 402 KQLAERRTDIFGVEETAIGKKIGEEE-IQKPEEKVTWDGHSGSMARTQQAAQANITLQEQ 460
++ R+T + + +Q P S++ + +T+
Sbjct: 430 LTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHP- 488
Query: 461 IEAIHKAKGLVPEDDTKEKIGPSKPNEIPQQPP----PPSSAT-----NIPSSAPP---- 507
++A+ P+ I P + PP PP+S T N+PS APP
Sbjct: 489 LQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQT 548
Query: 508 --------------------ITSVPRPPTMPPP-----VRTTVVSAVPVMPRPPMASVVR 542
+ + P P T PPP + T A P + PP+ +
Sbjct: 549 ASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPS 608
Query: 543 LPPGSVIAP---MPPIIHAPRINVVPMPPSAPP-------------------IMAPRPPP 580
P + P PP + P + P PP++PP + AP PP
Sbjct: 609 PPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP 668
Query: 581 MIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEP 615
P +PP +P +P+ PP PP + P
Sbjct: 669 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPP 703
Score = 64.7 bits (156), Expect = 3e-10
Identities = 51/157 (32%), Positives = 72/157 (45%), Gaps = 31/157 (19%)
Query: 482 PSKPNEIPQQPP--PPSSATNIPSSAPPITSVPRPPTMP---PPVRTTVVSAVPVMPRPP 536
P P+ I PP PP+ A+ PP+ +P PP P PP + A+P + PP
Sbjct: 581 PETPSSIATPPPQAPPALAS------PPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPP 634
Query: 537 MASVVRLPPGSVIA-PMPPIIHAPRINVVPMP---PSAPPIMAPRPPPM---IVPTAFVP 589
S PP S +A P P +A ++++ P P +PP+ AP PP + P+A P
Sbjct: 635 --SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPP 692
Query: 590 --------APPVAPVPAPAPMPPVHP---PPPMEDEP 615
APP+ P+P PP+ P PPP P
Sbjct: 693 SQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP 729
Score = 60.5 bits (145), Expect = 5e-09
Identities = 49/174 (28%), Positives = 69/174 (39%), Gaps = 29/174 (16%)
Query: 441 SGSMARTQQAAQANITLQEQ--IEAIHKAKGLVPEDDTKEKIGPSKPNEIPQQPPPPSSA 498
SG AR A A+ + + ++A+ + P D +GP + P P PS
Sbjct: 255 SGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS--PLATPSPSGT 312
Query: 499 TNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHA 558
P P + P P T+P P PP+A+ + L P S AP
Sbjct: 313 KARPVPPPDNAATPLPATLP--------------PSPPLATPLPLAPPSPSAP------- 351
Query: 559 PRINVVPMPPSAPPIMAP---RPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPP 609
P + +P PP+ PP AP PPM P + PP+ VP P + PP
Sbjct: 352 PSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPI-QVPHSLTSPSLQAPP 404
Score = 58.5 bits (140), Expect = 2e-08
Identities = 45/153 (29%), Positives = 60/153 (39%), Gaps = 26/153 (16%)
Query: 489 PQQPP----PPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRP--------- 535
PQ PP PP A P ++PP++ + P P + P P P
Sbjct: 619 PQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFS 678
Query: 536 PMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAP 595
P AS P + + PP + AP + V P PP++PP M+P P PP AP
Sbjct: 679 PPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPP-MSPSATP----------PPQAP 727
Query: 596 VPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P AP P+ PP P T +P
Sbjct: 728 PPLAAP--PLQVPPSPPASPPMSPSATPPPRVP 758
Score = 50.8 bits (120), Expect = 4e-06
Identities = 42/140 (30%), Positives = 55/140 (39%), Gaps = 24/140 (17%)
Query: 481 GPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASV 540
GPS P+ P PS P RPP + PP R A+ + P+A+
Sbjct: 256 GPSARGT-PRAPAHPSQPK------PKGLQALRPPQVTPP-RKDAAPALGPLSSSPLATP 307
Query: 541 VRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAP----- 595
P G+ P+PP P P+P + PP PP+ P P P AP
Sbjct: 308 S--PSGTKARPVPP----PDNAATPLPATLPP-----SPPLATPLPLAPPSPSAPPSLQT 356
Query: 596 VPAPAPMPPVHPPPPMEDEP 615
+P+P PP PP M P
Sbjct: 357 LPSPPATPPSQAPPSMTTPP 376
Score = 48.9 bits (115), Expect = 2e-05
Identities = 37/134 (27%), Positives = 52/134 (38%), Gaps = 22/134 (16%)
Query: 489 PQQPPPPSSATNIPSSAPPITSVPRPPTMPP-------PVRTTVVSAVPVMPRPPMASVV 541
P QP P + + PP + PR P P+ T S P PP +
Sbjct: 269 PSQPKPKG----LQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAA 324
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAP 601
P + + P PP+ A + + P PSAPP + P P PA P + P
Sbjct: 325 T-PLPATLPPSPPL--ATPLPLAPPSPSAPPSLQTLPSP--------PATPPSQAPPSMT 373
Query: 602 MPPVHPPPPMEDEP 615
PP+ PP ++ P
Sbjct: 374 TPPMQAPPSLQTIP 387
Score = 42.7 bits (99), Expect = 0.001
Identities = 91/397 (22%), Positives = 138/397 (34%), Gaps = 74/397 (18%)
Query: 300 GQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLP-----------PAPAPDEYLV- 347
G P PP +P PPP P TP + V KPL P AP
Sbjct: 23 GLLTPRPPGSPRPPP-PVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTR 81
Query: 348 SPITGEKIPASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLK-QLAE 406
S T + PAS+ R P + S V +PG ++ L +
Sbjct: 82 SAGTSSRNPASRPPASGRGERAPPA----------KNTSPGPVSSPGRASGTTRPGPLGQ 131
Query: 407 RRTDIFGVEETAIGKKIGEEE-------IQKPEEKVTWDGHSGSMARTQQAAQANITLQE 459
+ I E A GK + ++ T S +MAR +AA + L
Sbjct: 132 KGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPR 191
Query: 460 QIEAIHKAKGLVPEDDTKEKIGPSKPNEIPQQPPP----PSS--------ATNIPSSAPP 507
+ A+ P + ++ + + + + P PS+ + ++ SSA P
Sbjct: 192 PAPS---ARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP 248
Query: 508 ITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPM- 566
++S R + P T A P P+P +R PP + PR + P
Sbjct: 249 LSSPAR--SGPSARGTPRAPAHPSQPKPKGLQALR----------PPQVTPPRKDAAPAL 296
Query: 567 -PPSAPPIMAPRP--------PPMIVPTAFVPA--PPVAPVPAPAPMPPVHPPPPMEDEP 615
P S+ P+ P P PP +PA PP P+ P P+ P P P +
Sbjct: 297 GPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQT 356
Query: 616 TSKKLKTEDSLMPEEEFLRRNKGPVSIK----VQVPN 648
T S P + P S++ +QVP+
Sbjct: 357 LPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPH 393
Score = 42.4 bits (98), Expect = 0.002
Identities = 41/172 (23%), Positives = 60/172 (34%), Gaps = 34/172 (19%)
Query: 482 PSKPNEIPQQPPP----------PSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPV 531
PS P P Q PP PS T P P + P P P+ + + A
Sbjct: 358 PSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTS 417
Query: 532 MPRPPMASV-------VRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVP 584
+ P + + R S+ +P P PP +PP+ AP P P
Sbjct: 418 LGSPTLQATHSFLTMSPRQTQASLTSPSRP---------ASTPPDSPPLQAPLSLPASPP 468
Query: 585 TAFVPAPPVAPVPAPAPMPPV--------HPPPPMEDEPTSKKLKTEDSLMP 628
+P V+P+ +P + P+ H P L+T+ SL P
Sbjct: 469 LQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAP 520
>gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3
[Homo sapiens]
Length = 1125
Score = 72.0 bits (175), Expect = 2e-12
Identities = 45/138 (32%), Positives = 61/138 (44%), Gaps = 14/138 (10%)
Query: 472 PEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPV 531
PE++ + G + P P P +P PPI VP P T+PPP P
Sbjct: 637 PENEVAQNGGAETSHTEPVSPIPKP----LPVPVPPIP-VPAPITVPPP------QVPPH 685
Query: 532 MPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAP 591
P PP+ ++ P + +PP P VP PP PP + P PM +P F+P
Sbjct: 686 QPGPPVVGALQPPAFTPPLGIPPPGFGPG---VPPPPPPPPFLRPGFNPMHLPPGFLPPG 742
Query: 592 PVAPVPAPAPMPPVHPPP 609
P P+ P +PP H PP
Sbjct: 743 PPPPITPPVSIPPPHTPP 760
Score = 46.6 bits (109), Expect = 8e-05
Identities = 35/129 (27%), Positives = 44/129 (34%), Gaps = 30/129 (23%)
Query: 471 VPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVP 530
VP I P P QP PP+ +PP PP+ P
Sbjct: 666 VPPIPVPAPITVPPPQVPPHQP------------GPPVVGALQPPAFTPPLGIPPPGFGP 713
Query: 531 VMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPA 590
+P PP P PP + P N + +PP P P PPP I P +P
Sbjct: 714 GVPPPP--------------PPPPFLR-PGFNPMHLPPGFLP---PGPPPPITPPVSIPP 755
Query: 591 PPVAPVPAP 599
P P+ P
Sbjct: 756 PHTPPISIP 764
Score = 45.4 bits (106), Expect = 2e-04
Identities = 38/149 (25%), Positives = 60/149 (40%), Gaps = 19/149 (12%)
Query: 494 PPSSATNIPSS--APPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAP 551
PP++ TN+P+ P++ + P PV + ++ P ++ PPG
Sbjct: 788 PPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPG----- 842
Query: 552 MPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFV---------PAPPVAPVPAPAPM 602
MPP H R ++P P P +M PPP P F P PP P P M
Sbjct: 843 MPPP-HLQRFPLMPPRPMPPHMMHRGPPPG--PGGFAMPPPHGMKGPFPPHGPFVRPGGM 899
Query: 603 PPVHPPPPMEDEPTSKKLKTEDSLMPEEE 631
P + P P P + + + P+++
Sbjct: 900 PGLGGPGPGPGGPEDRDGRQQPPQQPQQQ 928
Score = 43.5 bits (101), Expect = 7e-04
Identities = 41/172 (23%), Positives = 62/172 (36%), Gaps = 32/172 (18%)
Query: 474 DDTKEKIGPSKPNEI-------PQQPPPPSSATNIPSSAPPITSVPRPPTMP-------- 518
DD E + SK + P PP+ +P++A P + P PP P
Sbjct: 268 DDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGM 327
Query: 519 -PPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPR 577
P T + PR M + + P + P+PP P ++P PP
Sbjct: 328 QQPAYTQHQNMDQFQPR--MMGIQQDPMHHQV-PLPPNGQMPGFGLLPTPPF-------- 376
Query: 578 PPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMPE 629
PPM P PP PV P P+ +P ++++ E + E
Sbjct: 377 -PPMAQPV----IPPTPPVQQPFQASFQAQNEPLTQKPHQQEMEVEQPCIQE 423
Score = 43.5 bits (101), Expect = 7e-04
Identities = 48/196 (24%), Positives = 64/196 (32%), Gaps = 52/196 (26%)
Query: 467 AKGLVPEDDTKEKIG----PSKPNEIPQQP--------------PPPSSATNIPSSA--- 505
A+G D+ + G P+ P +P P P P PS+
Sbjct: 770 ARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLG 829
Query: 506 --PPITSVPRPPTMPPPVRTTVVSAVPVMPRPPM-------------ASVVRLPPGSVIA 550
P + + RPP MPPP + P+MP PM PP +
Sbjct: 830 ARPGLIPLQRPPGMPPP----HLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKG 885
Query: 551 PMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHP--- 607
P PP H P + MP P P P PP P P P P P
Sbjct: 886 PFPP--HGPFVRPGGMPGLGGPGPGPGGPE---DRDGRQQPPQQPQQQPQPQAPQQPQQQ 940
Query: 608 ----PPPMEDEPTSKK 619
PPP + P +++
Sbjct: 941 QQQQPPPSQQPPPTQQ 956
Score = 42.4 bits (98), Expect = 0.002
Identities = 37/130 (28%), Positives = 52/130 (40%), Gaps = 41/130 (31%)
Query: 482 PSKP-NEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASV 540
P KP NE+ Q +S T P++ +P+P +P PV P P+ +
Sbjct: 634 PKKPENEVAQNGGAETSHTE------PVSPIPKP--LPVPV-----------PPIPVPAP 674
Query: 541 VRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPA 600
+ +PP V PP H P PP++ PP P +P P P
Sbjct: 675 ITVPPPQV----PP--HQP----------GPPVVGALQPPAFTPPLGIPPPGFGP----- 713
Query: 601 PMPPVHPPPP 610
+PP PPPP
Sbjct: 714 GVPPPPPPPP 723
Score = 32.3 bits (72), Expect = 1.6
Identities = 17/40 (42%), Positives = 20/40 (50%), Gaps = 8/40 (20%)
Query: 576 PRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEP 615
P+P P VP PP+ PVPAP +PP PP P
Sbjct: 659 PKPLP-------VPVPPI-PVPAPITVPPPQVPPHQPGPP 690
Score = 31.6 bits (70), Expect = 2.7
Identities = 17/42 (40%), Positives = 21/42 (50%), Gaps = 4/42 (9%)
Query: 303 VPPPPETPMPPPLPPTPDQVIVRKDYDPKASKP--LPPAPAP 342
+PPP P PP PP P +R ++P P LPP P P
Sbjct: 706 IPPPGFGPGVPPPPPPPP--FLRPGFNPMHLPPGFLPPGPPP 745
Score = 30.0 bits (66), Expect = 7.9
Identities = 16/45 (35%), Positives = 18/45 (40%), Gaps = 3/45 (6%)
Query: 5 PVQAVPPPPPVPTEP---KQPTEEEASSKEDSAPSKPVVGIIYPP 46
PV +P P PVP P P P PVVG + PP
Sbjct: 654 PVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPP 698
>gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2
[Homo sapiens]
Length = 1132
Score = 72.0 bits (175), Expect = 2e-12
Identities = 45/138 (32%), Positives = 61/138 (44%), Gaps = 14/138 (10%)
Query: 472 PEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPV 531
PE++ + G + P P P +P PPI VP P T+PPP P
Sbjct: 622 PENEVAQNGGAETSHTEPVSPIPKP----LPVPVPPIP-VPAPITVPPP------QVPPH 670
Query: 532 MPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAP 591
P PP+ ++ P + +PP P VP PP PP + P PM +P F+P
Sbjct: 671 QPGPPVVGALQPPAFTPPLGIPPPGFGPG---VPPPPPPPPFLRPGFNPMHLPPGFLPPG 727
Query: 592 PVAPVPAPAPMPPVHPPP 609
P P+ P +PP H PP
Sbjct: 728 PPPPITPPVSIPPPHTPP 745
Score = 46.6 bits (109), Expect = 8e-05
Identities = 35/129 (27%), Positives = 44/129 (34%), Gaps = 30/129 (23%)
Query: 471 VPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVP 530
VP I P P QP PP+ +PP PP+ P
Sbjct: 651 VPPIPVPAPITVPPPQVPPHQP------------GPPVVGALQPPAFTPPLGIPPPGFGP 698
Query: 531 VMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPA 590
+P PP P PP + P N + +PP P P PPP I P +P
Sbjct: 699 GVPPPP--------------PPPPFLR-PGFNPMHLPPGFLP---PGPPPPITPPVSIPP 740
Query: 591 PPVAPVPAP 599
P P+ P
Sbjct: 741 PHTPPISIP 749
Score = 45.4 bits (106), Expect = 2e-04
Identities = 38/149 (25%), Positives = 60/149 (40%), Gaps = 19/149 (12%)
Query: 494 PPSSATNIPSS--APPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAP 551
PP++ TN+P+ P++ + P PV + ++ P ++ PPG
Sbjct: 795 PPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPG----- 849
Query: 552 MPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFV---------PAPPVAPVPAPAPM 602
MPP H R ++P P P +M PPP P F P PP P P M
Sbjct: 850 MPPP-HLQRFPLMPPRPMPPHMMHRGPPPG--PGGFAMPPPHGMKGPFPPHGPFVRPGGM 906
Query: 603 PPVHPPPPMEDEPTSKKLKTEDSLMPEEE 631
P + P P P + + + P+++
Sbjct: 907 PGLGGPGPGPGGPEDRDGRQQPPQQPQQQ 935
Score = 43.5 bits (101), Expect = 7e-04
Identities = 41/172 (23%), Positives = 62/172 (36%), Gaps = 32/172 (18%)
Query: 474 DDTKEKIGPSKPNEI-------PQQPPPPSSATNIPSSAPPITSVPRPPTMP-------- 518
DD E + SK + P PP+ +P++A P + P PP P
Sbjct: 253 DDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGM 312
Query: 519 -PPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPR 577
P T + PR M + + P + P+PP P ++P PP
Sbjct: 313 QQPAYTQHQNMDQFQPR--MMGIQQDPMHHQV-PLPPNGQMPGFGLLPTPPF-------- 361
Query: 578 PPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMPE 629
PPM P PP PV P P+ +P ++++ E + E
Sbjct: 362 -PPMAQPV----IPPTPPVQQPFQASFQAQNEPLTQKPHQQEMEVEQPCIQE 408
Score = 43.5 bits (101), Expect = 7e-04
Identities = 48/196 (24%), Positives = 64/196 (32%), Gaps = 52/196 (26%)
Query: 467 AKGLVPEDDTKEKIG----PSKPNEIPQQP--------------PPPSSATNIPSSA--- 505
A+G D+ + G P+ P +P P P P PS+
Sbjct: 777 ARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLG 836
Query: 506 --PPITSVPRPPTMPPPVRTTVVSAVPVMPRPPM-------------ASVVRLPPGSVIA 550
P + + RPP MPPP + P+MP PM PP +
Sbjct: 837 ARPGLIPLQRPPGMPPP----HLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKG 892
Query: 551 PMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHP--- 607
P PP H P + MP P P P PP P P P P P
Sbjct: 893 PFPP--HGPFVRPGGMPGLGGPGPGPGGPE---DRDGRQQPPQQPQQQPQPQAPQQPQQQ 947
Query: 608 ----PPPMEDEPTSKK 619
PPP + P +++
Sbjct: 948 QQQQPPPSQQPPPTQQ 963
Score = 42.4 bits (98), Expect = 0.002
Identities = 37/130 (28%), Positives = 52/130 (40%), Gaps = 41/130 (31%)
Query: 482 PSKP-NEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASV 540
P KP NE+ Q +S T P++ +P+P +P PV P P+ +
Sbjct: 619 PKKPENEVAQNGGAETSHTE------PVSPIPKP--LPVPV-----------PPIPVPAP 659
Query: 541 VRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPA 600
+ +PP V PP H P PP++ PP P +P P P
Sbjct: 660 ITVPPPQV----PP--HQP----------GPPVVGALQPPAFTPPLGIPPPGFGP----- 698
Query: 601 PMPPVHPPPP 610
+PP PPPP
Sbjct: 699 GVPPPPPPPP 708
Score = 32.3 bits (72), Expect = 1.6
Identities = 17/40 (42%), Positives = 20/40 (50%), Gaps = 8/40 (20%)
Query: 576 PRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEP 615
P+P P VP PP+ PVPAP +PP PP P
Sbjct: 644 PKPLP-------VPVPPI-PVPAPITVPPPQVPPHQPGPP 675
Score = 31.6 bits (70), Expect = 2.7
Identities = 17/42 (40%), Positives = 21/42 (50%), Gaps = 4/42 (9%)
Query: 303 VPPPPETPMPPPLPPTPDQVIVRKDYDPKASKP--LPPAPAP 342
+PPP P PP PP P +R ++P P LPP P P
Sbjct: 691 IPPPGFGPGVPPPPPPPP--FLRPGFNPMHLPPGFLPPGPPP 730
Score = 30.0 bits (66), Expect = 7.9
Identities = 16/45 (35%), Positives = 18/45 (40%), Gaps = 3/45 (6%)
Query: 5 PVQAVPPPPPVPTEP---KQPTEEEASSKEDSAPSKPVVGIIYPP 46
PV +P P PVP P P P PVVG + PP
Sbjct: 639 PVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPP 683
>gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1
[Homo sapiens]
Length = 1147
Score = 72.0 bits (175), Expect = 2e-12
Identities = 45/138 (32%), Positives = 61/138 (44%), Gaps = 14/138 (10%)
Query: 472 PEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPV 531
PE++ + G + P P P +P PPI VP P T+PPP P
Sbjct: 637 PENEVAQNGGAETSHTEPVSPIPKP----LPVPVPPIP-VPAPITVPPP------QVPPH 685
Query: 532 MPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAP 591
P PP+ ++ P + +PP P VP PP PP + P PM +P F+P
Sbjct: 686 QPGPPVVGALQPPAFTPPLGIPPPGFGPG---VPPPPPPPPFLRPGFNPMHLPPGFLPPG 742
Query: 592 PVAPVPAPAPMPPVHPPP 609
P P+ P +PP H PP
Sbjct: 743 PPPPITPPVSIPPPHTPP 760
Score = 46.6 bits (109), Expect = 8e-05
Identities = 35/129 (27%), Positives = 44/129 (34%), Gaps = 30/129 (23%)
Query: 471 VPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVP 530
VP I P P QP PP+ +PP PP+ P
Sbjct: 666 VPPIPVPAPITVPPPQVPPHQP------------GPPVVGALQPPAFTPPLGIPPPGFGP 713
Query: 531 VMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPA 590
+P PP P PP + P N + +PP P P PPP I P +P
Sbjct: 714 GVPPPP--------------PPPPFLR-PGFNPMHLPPGFLP---PGPPPPITPPVSIPP 755
Query: 591 PPVAPVPAP 599
P P+ P
Sbjct: 756 PHTPPISIP 764
Score = 45.4 bits (106), Expect = 2e-04
Identities = 38/149 (25%), Positives = 60/149 (40%), Gaps = 19/149 (12%)
Query: 494 PPSSATNIPSS--APPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAP 551
PP++ TN+P+ P++ + P PV + ++ P ++ PPG
Sbjct: 810 PPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPG----- 864
Query: 552 MPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFV---------PAPPVAPVPAPAPM 602
MPP H R ++P P P +M PPP P F P PP P P M
Sbjct: 865 MPPP-HLQRFPLMPPRPMPPHMMHRGPPPG--PGGFAMPPPHGMKGPFPPHGPFVRPGGM 921
Query: 603 PPVHPPPPMEDEPTSKKLKTEDSLMPEEE 631
P + P P P + + + P+++
Sbjct: 922 PGLGGPGPGPGGPEDRDGRQQPPQQPQQQ 950
Score = 43.5 bits (101), Expect = 7e-04
Identities = 41/172 (23%), Positives = 62/172 (36%), Gaps = 32/172 (18%)
Query: 474 DDTKEKIGPSKPNEI-------PQQPPPPSSATNIPSSAPPITSVPRPPTMP-------- 518
DD E + SK + P PP+ +P++A P + P PP P
Sbjct: 268 DDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGM 327
Query: 519 -PPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPR 577
P T + PR M + + P + P+PP P ++P PP
Sbjct: 328 QQPAYTQHQNMDQFQPR--MMGIQQDPMHHQV-PLPPNGQMPGFGLLPTPPF-------- 376
Query: 578 PPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMPE 629
PPM P PP PV P P+ +P ++++ E + E
Sbjct: 377 -PPMAQPV----IPPTPPVQQPFQASFQAQNEPLTQKPHQQEMEVEQPCIQE 423
Score = 43.5 bits (101), Expect = 7e-04
Identities = 48/196 (24%), Positives = 64/196 (32%), Gaps = 52/196 (26%)
Query: 467 AKGLVPEDDTKEKIG----PSKPNEIPQQP--------------PPPSSATNIPSSA--- 505
A+G D+ + G P+ P +P P P P PS+
Sbjct: 792 ARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLG 851
Query: 506 --PPITSVPRPPTMPPPVRTTVVSAVPVMPRPPM-------------ASVVRLPPGSVIA 550
P + + RPP MPPP + P+MP PM PP +
Sbjct: 852 ARPGLIPLQRPPGMPPP----HLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKG 907
Query: 551 PMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHP--- 607
P PP H P + MP P P P PP P P P P P
Sbjct: 908 PFPP--HGPFVRPGGMPGLGGPGPGPGGPE---DRDGRQQPPQQPQQQPQPQAPQQPQQQ 962
Query: 608 ----PPPMEDEPTSKK 619
PPP + P +++
Sbjct: 963 QQQQPPPSQQPPPTQQ 978
Score = 42.4 bits (98), Expect = 0.002
Identities = 37/130 (28%), Positives = 52/130 (40%), Gaps = 41/130 (31%)
Query: 482 PSKP-NEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASV 540
P KP NE+ Q +S T P++ +P+P +P PV P P+ +
Sbjct: 634 PKKPENEVAQNGGAETSHTE------PVSPIPKP--LPVPV-----------PPIPVPAP 674
Query: 541 VRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPA 600
+ +PP V PP H P PP++ PP P +P P P
Sbjct: 675 ITVPPPQV----PP--HQP----------GPPVVGALQPPAFTPPLGIPPPGFGP----- 713
Query: 601 PMPPVHPPPP 610
+PP PPPP
Sbjct: 714 GVPPPPPPPP 723
Score = 32.3 bits (72), Expect = 1.6
Identities = 17/40 (42%), Positives = 20/40 (50%), Gaps = 8/40 (20%)
Query: 576 PRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEP 615
P+P P VP PP+ PVPAP +PP PP P
Sbjct: 659 PKPLP-------VPVPPI-PVPAPITVPPPQVPPHQPGPP 690
Score = 31.6 bits (70), Expect = 2.7
Identities = 17/42 (40%), Positives = 21/42 (50%), Gaps = 4/42 (9%)
Query: 303 VPPPPETPMPPPLPPTPDQVIVRKDYDPKASKP--LPPAPAP 342
+PPP P PP PP P +R ++P P LPP P P
Sbjct: 706 IPPPGFGPGVPPPPPPPP--FLRPGFNPMHLPPGFLPPGPPP 745
Score = 30.0 bits (66), Expect = 7.9
Identities = 16/45 (35%), Positives = 18/45 (40%), Gaps = 3/45 (6%)
Query: 5 PVQAVPPPPPVPTEP---KQPTEEEASSKEDSAPSKPVVGIIYPP 46
PV +P P PVP P P P PVVG + PP
Sbjct: 654 PVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPP 698
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 72.0 bits (175), Expect = 2e-12
Identities = 91/370 (24%), Positives = 124/370 (33%), Gaps = 96/370 (25%)
Query: 293 GSDDEEEGQKVPPPP----------ETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAP 342
G+ D E ++ P PP E P PP PP PD + P P +P
Sbjct: 421 GARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSP 480
Query: 343 DE-YLVSPITGEKIPASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSL 401
L S G + P + + + L + R + +RE SD E+ G I SS
Sbjct: 481 GTPTLESSPAGPEKPHDSLDSRIEMLLKEQR---TKLLFLREPDSDTELQMEGSPISSSS 537
Query: 402 KQLAERRTDIFGVEETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQI 461
QL+ P + G T +++ + T E I
Sbjct: 538 SQLS-------------------------PLAPFGTNSQPGFRGPTPPSSRPSSTGLEDI 572
Query: 462 EAIHKAKGLVPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAP--------------- 506
+P+ D E++ P +P PP A + +A
Sbjct: 573 SPTP-----LPDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEK 627
Query: 507 ----------------------PITSV--PRPPTMPPPVRTTVVSAV--PVMPRPPMASV 540
PITS P+P + P +V P +P PP
Sbjct: 628 MDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPP---- 683
Query: 541 VRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPA 600
PPG P PP P+ PMPP PP P PPP P VP PP+ P P
Sbjct: 684 ---PPGFPPLPPPPPPPPPQPG-FPMPPPLPP--PPPPPPPAHPAVTVPPPPL-PAPPGV 736
Query: 601 PMPPVHPPPP 610
P PP+ PP P
Sbjct: 737 PPPPILPPLP 746
Score = 65.5 bits (158), Expect = 2e-10
Identities = 99/424 (23%), Positives = 144/424 (33%), Gaps = 56/424 (13%)
Query: 194 KEEEEKEKERVAYAQIDWHDFVVVETVDFQPNEQGNFPPPTTPEELGA------RILIQE 247
+E+EE E+ER D D E P G P P EL + + + E
Sbjct: 989 EEDEESERER----DRDMAD-TPCELAKRDPKGVGVRRRPARPLELDSGGEEDEKESLSE 1043
Query: 248 RYEKFGESEEVEMEVESDEEDDKQEKAEEPPSQLDQDT---QVQDMDEGSDDEEEGQKVP 304
E E EE E E E +++DD + D+DT + + DEG DEEE +
Sbjct: 1044 EQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEEETVSI- 1102
Query: 305 PPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKMQEHM 364
+ T +S+ P + +E +V+ E+ +M
Sbjct: 1103 ------VTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEE 1156
Query: 365 RIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGVEETAIGKKIG 424
+ P EQ ++ APG SL E DI
Sbjct: 1157 SMASAGPEDFEQ--------DGEEAALAPGAPAVDSLGM--EEEVDI------------- 1193
Query: 425 EEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKAKGLVPEDDTKEKIG--P 482
E E PEE+ + ++ A + +E + A L PE KE P
Sbjct: 1194 ETEAVAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPP 1253
Query: 483 SKPNEIPQQ----PPPPSSATNIPSSAP-PITSVPRPPTMPPPVRTTVVSAVPVMPRPPM 537
P P+ P P +P P P PRPP+ PP TT S V P P
Sbjct: 1254 LSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLA 1313
Query: 538 ASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVP 597
PG + + VP P P ++ + + + VP P + P
Sbjct: 1314 EDHPPHTPGL----CGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFS-YP 1368
Query: 598 APAP 601
AP+P
Sbjct: 1369 APSP 1372
Score = 61.6 bits (148), Expect = 2e-09
Identities = 112/474 (23%), Positives = 168/474 (35%), Gaps = 76/474 (16%)
Query: 192 RKKEEEEKEKERVAYAQIDWHDFVVVETVDFQPNEQGNFPPPTTPEELGARILIQERYEK 251
R++EEEE+E+E VA + DF+ + + P P +
Sbjct: 1141 REEEEEEEEEEMVAEESM-----ASAGPEDFEQDGEEAALAPGAPA-----------VDS 1184
Query: 252 FGESEEVEMEVESDEEDDKQEKAEEPPSQL--DQDTQVQDMDEGSDDEEEGQKV----PP 305
G EEV++E E+ +++ +EPP + ++ ++ E +EG + PP
Sbjct: 1185 LGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPP 1244
Query: 306 PPETPMPPPLPP--TPDQVIVRKDYDPKASKPLP-----PAPAPDEYLVSPITGEKIPAS 358
E PPL P P+ + + +P PLP P P P P E AS
Sbjct: 1245 AKEVEARPPLSPERAPEHDL-EVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDAS 1303
Query: 359 KMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGVEETA 418
+ P L + D + PGL + Q E G E
Sbjct: 1304 HPS-------VPPEPLAE----------DHPPHTPGLCGSLAKSQSTETVPATPGGEPPL 1346
Query: 419 IGKKIGEE--EIQKPEEKVTWDG-----HSGSMARTQ-QAAQANITLQEQIEAIHKAKGL 470
G G Q P ++ SG + RT + T E +
Sbjct: 1347 SGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCP 1406
Query: 471 VPEDDTKEKIGPSKPNEIPQQ--PPPPSSATNIPSSAPPITSVP-RPPT-MPPPVRTTVV 526
+P E+ GP + + P P +P + P + R PT +PP + +
Sbjct: 1407 LPTGRRDERSGPLASPVLLETGLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLA 1466
Query: 527 SAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVV----------PMPPSAPPIMAP 576
S P M R P R P S+++ P++ P + P P P P
Sbjct: 1467 SCPPPMKRKPGRP--RRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPSTHDP 1524
Query: 577 RPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMPEE 630
R + A +PAPP P P P P PPPP+ EPT K D+ P E
Sbjct: 1525 RTVTLDFRNAGIPAPPPPLPPQPPPPP---PPPPV--EPTKLPFKELDNQWPSE 1573
Score = 59.7 bits (143), Expect = 9e-09
Identities = 86/354 (24%), Positives = 119/354 (33%), Gaps = 63/354 (17%)
Query: 231 PPPTTPEELGARILIQERYEKFGESEEVEMEVESDEEDDKQEKAEEPPSQLD-------- 282
PP T ELG R FG S E + + E+P LD
Sbjct: 456 PPDTNSMELGGR-------PTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLK 508
Query: 283 -QDTQVQDMDE-GSDDEEEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAP 340
Q T++ + E SD E + + P + PL P + P P PP+
Sbjct: 509 EQRTKLLFLREPDSDTELQMEGSPISSSSSQLSPLAP------FGTNSQPGFRGPTPPSS 562
Query: 341 APDEYLVSPITGEKIPASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESS 400
P + I+ +P S E + +GL PR E P D
Sbjct: 563 RPSSTGLEDISPTPLPDSDEDEELDLGL-GPR-------------PPPEPGPP--DPAGL 606
Query: 401 LKQLAERRTDIFGVEETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQ 460
L Q AE D+ G + T +K+ E + E+ D S T + +
Sbjct: 607 LSQTAEVALDLVG-DRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPG 665
Query: 461 IEAIHKAKGLVPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPP 520
A+ L P T P +P PPPP P P +P PP PPP
Sbjct: 666 AAAVAAPSVLAP---TLPLPPPPGFPPLPPPPPPPPPQPGFPMPPP----LPPPPPPPPP 718
Query: 521 VRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIM 574
V P +P PP +PP ++ P+P P PP P+M
Sbjct: 719 AHPAVTVPPPPLPAPP-----GVPPPPILPPLP-----------PFPPGLFPVM 756
Score = 44.7 bits (104), Expect = 3e-04
Identities = 73/374 (19%), Positives = 131/374 (35%), Gaps = 44/374 (11%)
Query: 273 KAEEPPS--------QLDQDTQVQDMDEGSDDEEEGQKVPPPPETPMPPPLPPTPDQVIV 324
K +EPP +L T V + DE S+ E + P E P V V
Sbjct: 965 KRKEPPDTTSSGDQKRLRPSTSVDEEDEESERERDRDMADTPCELAKRDP-----KGVGV 1019
Query: 325 RKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKMQEHMRIGLLDPRWLEQRDRSIREK 384
R+ + ++PL +E ++ E+ + +E E+ + +
Sbjct: 1020 RR----RPARPLELDSGGEEDEKESLSEEQESTEEEEEAEE---------EEEEEDDDDD 1066
Query: 385 QSDDEVYAPGLDIESSLKQLAERRTDIFGVEETAIGKKIGEEEIQKPEEKVTWDGHSGSM 444
SDD + D +++L + +E+ EET I + + T S
Sbjct: 1067 DSDDRDESENDDEDTALSEASEKDEGDSDEEETV--------SIVTSKAEATSSSESSES 1118
Query: 445 ARTQQAAQANITLQEQIEAIHKAKGLVPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSS 504
+ + +++++ + E E + + E++ + S + P+ +
Sbjct: 1119 SEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEAALAPG 1178
Query: 505 APPITSVPRPPTMPPPVRTTVVSAVPVM-PRPPMASVVRLPPGSVIAPMPP-IIHAPRIN 562
AP + S+ + P M PP+ V P S P P + +
Sbjct: 1179 APAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAML 1238
Query: 563 VVPMPPSA-----PPIMAPRPPPMIVPTAFVPAPPVA-PVPAPAPMPPVHPPPPMEDEPT 616
+ P PP+ PP+ R P + P PP+ P+P P+PP PP P P
Sbjct: 1239 LSPEPPAKEVEARPPLSPERAPEHDLEVE--PEPPMMLPLPLQPPLPPPRPPRPPSPPPE 1296
Query: 617 SKKLKTEDSLMPEE 630
+ +P E
Sbjct: 1297 PETTDASHPSVPPE 1310
Score = 44.7 bits (104), Expect = 3e-04
Identities = 39/158 (24%), Positives = 55/158 (34%), Gaps = 29/158 (18%)
Query: 482 PSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + PPP P +PP P + PP + + ++P P
Sbjct: 1459 PLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQ---- 1514
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP----PSAPPIMAPRPPPMIVPTAFVPAPPVAPVP 597
P+ P H PR + P+ PP + P+PPP P PPV P
Sbjct: 1515 --------TPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPP------PPPPPVEPTK 1560
Query: 598 APA-------PMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P P + P P DE T + ++ S P
Sbjct: 1561 LPFKELDNQWPSEAIPPGPRGRDEVTEEYMELAKSRGP 1598
Score = 34.7 bits (78), Expect = 0.32
Identities = 19/50 (38%), Positives = 24/50 (48%), Gaps = 4/50 (8%)
Query: 295 DDEEEGQKVPPPPETPMPPPLPPTPDQVIVR---KDYDPK-ASKPLPPAP 340
D G PPPP P PPP PP P + K+ D + S+ +PP P
Sbjct: 1530 DFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPPGP 1579
Score = 34.3 bits (77), Expect = 0.42
Identities = 31/112 (27%), Positives = 36/112 (32%), Gaps = 21/112 (18%)
Query: 503 SSAPPITSVPRPPTM----PPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHA 558
SS PP + P+ PPP + T P V PP P P A
Sbjct: 363 SSGPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPP----PPEEPTATA 418
Query: 559 PRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPP 610
S AP PPP+ PP P+ P P PPPP
Sbjct: 419 ----AFGARDSGEFRRAPAPPPL---------PPAEPLAKEKPGTPPGPPPP 457
Score = 33.9 bits (76), Expect = 0.55
Identities = 40/188 (21%), Positives = 57/188 (30%), Gaps = 59/188 (31%)
Query: 223 QPNEQGNFPPPTTPEELGARILIQERYEKFGESEEVEMEVESDEEDDKQEKAEEPPSQLD 282
QP +G PP + P G + E EE+++ + + +P L
Sbjct: 551 QPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGL--GPRPPPEPGPPDPAGLLS 608
Query: 283 QDTQV------------QDMDEG----------SDDEEEGQKV----------------- 303
Q +V + MDEG SDDE +
Sbjct: 609 QTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAA 668
Query: 304 --------------PPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSP 349
PPP P+PPP PP P Q + P PP P P +
Sbjct: 669 VAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQ----PGFPMPPPLPPPPPPPPPAHPAVT 724
Query: 350 ITGEKIPA 357
+ +PA
Sbjct: 725 VPPPPLPA 732
>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
sapiens]
Length = 505
Score = 71.6 bits (174), Expect = 2e-12
Identities = 47/135 (34%), Positives = 56/135 (41%), Gaps = 25/135 (18%)
Query: 486 NEIPQQ---PPPPSSATNIPSSAPPITSVPRPPTM-------PPPVRTTVVSAVPVMPRP 535
NE+ +Q PPPPS P PP S P PP PPP R + P P
Sbjct: 270 NELRRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSR 329
Query: 536 PMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAP 595
P +V PP + P PP + PS+ P P PPP ++ V PP
Sbjct: 330 PSVAVPPPPPNRMYPPPPPAL-----------PSSAPSGPPPPPPSVLGVGPVAPPP--- 375
Query: 596 VPAPAPMPPVHPPPP 610
P P P PP PPPP
Sbjct: 376 -PPPPPPPPGPPPPP 389
Score = 68.2 bits (165), Expect = 3e-11
Identities = 46/147 (31%), Positives = 58/147 (39%), Gaps = 17/147 (11%)
Query: 464 IHKAKGLVPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRT 523
I K G+ + + P P PPPP + S PP + R PPP R
Sbjct: 259 IEKTGGVEAVKNELRRQAPPPPPPSRGGPPPPPPPPH-NSGPPPPPARGRGAPPPPPSRA 317
Query: 524 TVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIV 583
+ P P P +V PP + P PP + PS+ P P PPP ++
Sbjct: 318 PTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPAL-----------PSSAPSGPPPPPPSVL 366
Query: 584 PTAFVPAPPVAPVPAPAPMPPVHPPPP 610
PVAP P P P PP PPPP
Sbjct: 367 GVG-----PVAPPPPPPPPPPPGPPPP 388
Score = 34.3 bits (77), Expect = 0.42
Identities = 19/49 (38%), Positives = 23/49 (46%), Gaps = 3/49 (6%)
Query: 2 PAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPV---VGIIYPPP 47
P+ P AVPPPPP P P +S+ P P VG + PPP
Sbjct: 327 PSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPP 375
Score = 32.3 bits (72), Expect = 1.6
Identities = 16/49 (32%), Positives = 22/49 (44%), Gaps = 3/49 (6%)
Query: 2 PAGPVQAVPPPPPV---PTEPKQPTEEEASSKEDSAPSKPVVGIIYPPP 47
P P + PPPPP P P+ ++ PS+P V + PPP
Sbjct: 291 PPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPP 339
Score = 32.0 bits (71), Expect = 2.1
Identities = 12/20 (60%), Positives = 12/20 (60%)
Query: 300 GQKVPPPPETPMPPPLPPTP 319
G PPPP P PPP PP P
Sbjct: 369 GPVAPPPPPPPPPPPGPPPP 388
Score = 31.6 bits (70), Expect = 2.7
Identities = 17/42 (40%), Positives = 20/42 (47%), Gaps = 3/42 (7%)
Query: 482 PSKPNEIPQ-QPPPPSSATNIPSSAPPITSVPRPP--TMPPP 520
P+ P+ P PPPP S + APP P PP PPP
Sbjct: 348 PALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGPPPPP 389
Score = 31.2 bits (69), Expect = 3.6
Identities = 19/52 (36%), Positives = 20/52 (38%), Gaps = 12/52 (23%)
Query: 303 VPPPPET---PMPPPL---------PPTPDQVIVRKDYDPKASKPLPPAPAP 342
VPPPP P PPP PP P V+ P P PP P P
Sbjct: 334 VPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGP 385
Score = 30.4 bits (67), Expect = 6.1
Identities = 17/44 (38%), Positives = 20/44 (45%), Gaps = 4/44 (9%)
Query: 300 GQKVPPPP----ETPMPPPLPPTPDQVIVRKDYDPKASKPLPPA 339
G+ PPPP T PPP PP+ V V + P PPA
Sbjct: 306 GRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPA 349
Score = 30.0 bits (66), Expect = 7.9
Identities = 18/63 (28%), Positives = 23/63 (36%), Gaps = 8/63 (12%)
Query: 304 PPPPETPMPPPLP--------PTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKI 355
PPPP PPP P P P + P S+P P P + P +
Sbjct: 291 PPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPAL 350
Query: 356 PAS 358
P+S
Sbjct: 351 PSS 353
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 71.6 bits (174), Expect = 2e-12
Identities = 85/355 (23%), Positives = 126/355 (35%), Gaps = 68/355 (19%)
Query: 303 VPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKMQ- 361
+PPPP P PPP PP P PLP AP +P+ + +++Q
Sbjct: 628 LPPPPPPPPPPPPPPPPPP------------PPLPSQSAPSAGSAAPMFVKYSTITRLQN 675
Query: 362 --EH------------MRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAER 407
+H M+ + P+ L + + PG S++ QL
Sbjct: 676 ASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPG----SAMAQL--- 728
Query: 408 RTDIFGVEETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKA 467
+ + + P K+ H +A I +A K
Sbjct: 729 -------KPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKP 781
Query: 468 KGLVPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPV------ 521
+P + + + P P P PP + P P PPT P PV
Sbjct: 782 LVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLP 841
Query: 522 -RTTVVSAVPVMPRPPMASVVR-----LPPGSVIAPMPPIIHAPRINVVP--MPPSAPPI 573
+ + + P P P+ SVV+ PP P PP + + + VP + P +PP
Sbjct: 842 KQQSFCAKPPPSPLSPVPSVVKQIASQFPP----PPTPPAMESQPLKPVPANVAPQSPPA 897
Query: 574 MAPRP---PPMI-VPTAFVPAPP-----VAPVPAPAPMPPVHPPPPMEDEPTSKK 619
+ +P P I VP+ P PP V P P P+P+P PPPP PT K
Sbjct: 898 VKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDK 952
Score = 67.8 bits (164), Expect = 3e-11
Identities = 48/164 (29%), Positives = 61/164 (37%), Gaps = 23/164 (14%)
Query: 482 PSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAV------------ 529
P P P PPPP +PS + P P + T + +A
Sbjct: 630 PPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTP 689
Query: 530 PVMPRPPMASVVRLPPGSVIAPMPPIIHAP-------RINVVPMPPSAPPIMAPRPPPMI 582
PVM + + +PP V+ P PP P ++ P PS P AP PP I
Sbjct: 690 PVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKI 749
Query: 583 VP----TAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKT 622
T P P P P PAP+PP PP P+ P KT
Sbjct: 750 HQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKT 793
Score = 58.5 bits (140), Expect = 2e-08
Identities = 46/146 (31%), Positives = 55/146 (37%), Gaps = 35/146 (23%)
Query: 489 PQQPPPPSSATNIPSSAPPITSVPRP-PTMPPPVRTTVVSAVPVMPRPPMASVVRLP--P 545
P PPPP +P APP V P PT V V A P P PP+ + P P
Sbjct: 761 PTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFP 820
Query: 546 GSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPV 605
S I P PP PP+ P PP + +F PP P+P+ PV
Sbjct: 821 ASYIPPSPP---------------TPPVPVP-PPTLPKQQSFCAKPP------PSPLSPV 858
Query: 606 ----------HPPPPMEDEPTSKKLK 621
PPPP S+ LK
Sbjct: 859 PSVVKQIASQFPPPPTPPAMESQPLK 884
Score = 43.9 bits (102), Expect = 5e-04
Identities = 20/48 (41%), Positives = 27/48 (56%)
Query: 569 SAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPT 616
S P ++P+P + TA P+PP+ P P P P PP PPPP P+
Sbjct: 604 SLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPS 651
Score = 39.7 bits (91), Expect = 0.010
Identities = 19/53 (35%), Positives = 24/53 (45%), Gaps = 6/53 (11%)
Query: 565 PMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPTS 617
P P P A +P P + P PP P P P P PP PP P + P++
Sbjct: 611 PQPKIVTPYTASQPSPPL------PPPPPPPPPPPPPPPPPPPPLPSQSAPSA 657
Score = 38.9 bits (89), Expect = 0.017
Identities = 52/191 (27%), Positives = 69/191 (36%), Gaps = 26/191 (13%)
Query: 472 PEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITS-VPRPPTMPPPVRTTVVSAVP 530
P I S E P+ P PS + + PP S P T+PPP A P
Sbjct: 973 PTPQRNSSIKSSSGAEHPE-PKRPSVDSLVSKFTPPAESGSPSKETLPPP-------AAP 1024
Query: 531 VMPRPPMASVVRLP----PGSVIAPMPPIIHAPRINVV--PMPPSAPPIMAPRP------ 578
P S V LP G V A P + + +VV P PPS P P
Sbjct: 1025 PKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPL 1084
Query: 579 PPMIVPTAFV--PAPPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMPEEEFLRRN 636
PP+ +P F +P VA V P P ++ P + K DS + +
Sbjct: 1085 PPIEIPAVFSGNTSPKVAVV---NPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQ 1141
Query: 637 KGPVSIKVQVP 647
++ QVP
Sbjct: 1142 PTMATVVPQVP 1152
Score = 38.5 bits (88), Expect = 0.022
Identities = 25/73 (34%), Positives = 31/73 (42%), Gaps = 11/73 (15%)
Query: 552 MPPIIHAPRINVVPMPPS--APPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPP 609
+PP+ P+I V P S +PP+ P PPP P PP P P P P+P P
Sbjct: 606 VPPLSPQPKI-VTPYTASQPSPPLPPPPPPP--------PPPPPPPPPPPPPLPSQSAPS 656
Query: 610 PMEDEPTSKKLKT 622
P K T
Sbjct: 657 AGSAAPMFVKYST 669
Score = 37.7 bits (86), Expect = 0.038
Identities = 51/206 (24%), Positives = 66/206 (32%), Gaps = 44/206 (21%)
Query: 482 PSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPP----- 536
P P PPPP S P PP T+ P P P + T ++ P +PP
Sbjct: 918 PPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQR 977
Query: 537 MASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVP------TAFVPA 590
+S+ P P + + P S P PPP P + V
Sbjct: 978 NSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNL 1037
Query: 591 PPV---------APV------------PAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMPE 629
P V APV P+P PPPP + P +P
Sbjct: 1038 PGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELP-----------LPP 1086
Query: 630 EEFLRRNKGPVSIKVQVPNMQDKTEW 655
E G S KV V N Q + +W
Sbjct: 1087 IEIPAVFSGNTSPKVAVVNPQPQ-QW 1111
Score = 35.8 bits (81), Expect = 0.14
Identities = 37/141 (26%), Positives = 49/141 (34%), Gaps = 27/141 (19%)
Query: 230 FPPPTTPEELGARILIQERYEKFGESEEVEMEVESDEEDDKQEKAEEPPSQLDQDTQVQD 289
FPPP TP + ++ L + V V + K + PS + V
Sbjct: 869 FPPPPTPPAMESQPL-----------KPVPANVAPQSPPAVKAKPKWQPSSIP----VPS 913
Query: 290 MDEGSDDEEEGQKVPPPPETPMPPPLP-------PTPDQVIVRKDYDPKASKPLPPAPAP 342
D E PPPP +P+P P P PTPD+ K S P P P
Sbjct: 914 PDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPP 973
Query: 343 DEYLVSPITGEKIPASKMQEH 363
+P I +S EH
Sbjct: 974 -----TPQRNSSIKSSSGAEH 989
Score = 33.5 bits (75), Expect = 0.72
Identities = 17/56 (30%), Positives = 25/56 (44%), Gaps = 10/56 (17%)
Query: 2 PAGPVQAVPPPPPVP----TEPKQPTEEEASSKEDSAPSKPVVGII------YPPP 47
PA P +PP PP P P P ++ +K +P PV ++ +PPP
Sbjct: 817 PAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPP 872
Score = 33.1 bits (74), Expect = 0.94
Identities = 43/158 (27%), Positives = 53/158 (33%), Gaps = 64/158 (40%)
Query: 496 SSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPI 555
SS + S P TS+ P + P + T ++ P P PP P PP
Sbjct: 590 SSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPP--------------PPPP- 634
Query: 556 IHAPRINVVPMPPSAPPIMAPRPPPMI----VPTA------FV----------------- 588
P PP PP P PPP + P+A FV
Sbjct: 635 ---------PPPPPPPP---PPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGA 682
Query: 589 ----PAPPVAPVPAPAP---MPP---VHPPPPMEDEPT 616
P PPV + P +PP V PPPP PT
Sbjct: 683 LFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPT 720
Score = 32.0 bits (71), Expect = 2.1
Identities = 22/59 (37%), Positives = 28/59 (47%), Gaps = 3/59 (5%)
Query: 2 PAGPVQAVPPPPPVPTEPKQPTEEEASS--KEDSAPSKPVVGIIYPPPEVRNIVDKTAS 58
P P VP PPP P PT +++ S K+ S S P G PP RN K++S
Sbjct: 928 PPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSP-GGKKPPPTPQRNSSIKSSS 985
Score = 30.8 bits (68), Expect = 4.6
Identities = 17/42 (40%), Positives = 18/42 (42%), Gaps = 5/42 (11%)
Query: 301 QKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAP 342
Q PP P PP+PP Q Y P S P PP P P
Sbjct: 800 QAAPPTPT----PPVPPAKKQPAFPASYIP-PSPPTPPVPVP 836
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 71.2 bits (173), Expect = 3e-12
Identities = 51/148 (34%), Positives = 59/148 (39%), Gaps = 15/148 (10%)
Query: 482 PSKPNEIPQQPPP---PSSATNIPSSAPPITSVPRPPTM----PPPVRTTVVSAVPVMPR 534
PS P PPP PS T PS P T+ P PPT PPP TT S P
Sbjct: 1454 PSPPISTTTTPPPTTTPSPPTTTPS---PPTTTPSPPTTTTTTPPP--TTTPSPPTTTPI 1508
Query: 535 PPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVA 594
P AS LPP + +P P P PP+ PI P + PT P+PP
Sbjct: 1509 TPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTT-TPSPP-- 1565
Query: 595 PVPAPAPMPPVHPPPPMEDEPTSKKLKT 622
P P P P PP P+ + T
Sbjct: 1566 PTTTTTPPPTTTPSPPTTTTPSPPTITT 1593
Score = 67.8 bits (164), Expect = 3e-11
Identities = 46/146 (31%), Positives = 53/146 (36%), Gaps = 19/146 (13%)
Query: 482 PSKPNEIPQQPPP---PSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVP-------- 530
PS P PPP PS T P + P T+ P T P P TT + P
Sbjct: 1484 PSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPT 1543
Query: 531 VMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPIMAPRPPPMIV-- 583
P P S LPP + +P P P P P PS P I PPP
Sbjct: 1544 TTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPS 1603
Query: 584 -PTAFVPAPPVAPVPAPAPMPPVHPP 608
PT PP P+P P+ PP
Sbjct: 1604 PPTTTTTTPPPTTTPSPPTTTPITPP 1629
Score = 67.0 bits (162), Expect = 6e-11
Identities = 48/155 (30%), Positives = 61/155 (39%), Gaps = 29/155 (18%)
Query: 482 PSKPNEIPQQPPPPSSATNIPSS---APPITSVPRPP---TMPPPVRTTVVSAVPVMPRP 535
PS P P PPP+S T +P + +PP T+ PP T PP+ TT P P
Sbjct: 1399 PSPPTTTPS--PPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSP 1456
Query: 536 PMASVVRLPPGSV------------IAPMPPIIHA--PRINVVPMPPSAPPIMAPRPPPM 581
P+++ PP + P PP P P PP+ PI P
Sbjct: 1457 PISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTT 1516
Query: 582 IVPTAFVPAPP----VAPVPAPAPMPPVHPP--PP 610
+ PT P+PP P P P PP P PP
Sbjct: 1517 LPPTT-TPSPPTTTTTTPPPTTTPSPPTTTPITPP 1550
Score = 67.0 bits (162), Expect = 6e-11
Identities = 40/146 (27%), Positives = 54/146 (36%), Gaps = 9/146 (6%)
Query: 482 PSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPP--PVRTTVVSAVPVMPRPPMAS 539
PS P P P S ++ PP T+ P PPT P P +T P PP +
Sbjct: 1470 PSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTT 1529
Query: 540 VVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIV---PTAFVPAPPVAPV 596
PP + +P P + +PP+ P PPP P P+PP
Sbjct: 1530 TTTPPPTTTPSPPTTTPITPPTSTTTLPPTTT----PSPPPTTTTTPPPTTTPSPPTTTT 1585
Query: 597 PAPAPMPPVHPPPPMEDEPTSKKLKT 622
P+P + PPP P + T
Sbjct: 1586 PSPPTITTTTPPPTTTPSPPTTTTTT 1611
Score = 66.6 bits (161), Expect = 8e-11
Identities = 48/162 (29%), Positives = 58/162 (35%), Gaps = 19/162 (11%)
Query: 482 PSKPNEIPQQPPP---PSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVP-------- 530
PS P PPP PS T P + P T+ P T P P TT + P
Sbjct: 1523 PSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPT 1582
Query: 531 -VMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVP 589
P PP + PP + +P P P PP+ PI P + PT P
Sbjct: 1583 TTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTT-TP 1641
Query: 590 APP----VAPVPAPAPMPP--VHPPPPMEDEPTSKKLKTEDS 625
+PP P P P PP P PP+ T T S
Sbjct: 1642 SPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSS 1683
Score = 66.2 bits (160), Expect = 1e-10
Identities = 48/169 (28%), Positives = 65/169 (38%), Gaps = 25/169 (14%)
Query: 482 PSKPNEIPQQPP------PPSSATNIP---SSAPPITSVPRPPTMPPPVRTTVVSAVP-- 530
PS P P PP PP++ + P ++ PP T+ P PPT P T+ + P
Sbjct: 1539 PSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPP 1598
Query: 531 -VMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAP----RPPPMIV-- 583
P PP + PP + +P P + +PP+ P P PPP
Sbjct: 1599 TTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPS 1658
Query: 584 -PTAFVPAPPV----APVPAPAPMPPV--HPPPPMEDEPTSKKLKTEDS 625
PT P+PP+ P P P P+ P PP T T S
Sbjct: 1659 PPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSS 1707
Score = 64.3 bits (155), Expect = 4e-10
Identities = 51/165 (30%), Positives = 64/165 (38%), Gaps = 30/165 (18%)
Query: 482 PSKPNEIPQQPPP------PSSATNIP----SSAPPITSVPRPPTM----PPPVRTTVVS 527
PS P PPP P++ T P ++ PP T+ P PPT PPP TT S
Sbjct: 1562 PSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPP--TTTPS 1619
Query: 528 AVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPS----APPIMAPRPPPMIV 583
P P S LPP + +P P P P PP+ +PPI PP
Sbjct: 1620 PPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPP--- 1676
Query: 584 PTAFVPAPPVAPVPAP------APMPPVHPPPPMEDEPTSKKLKT 622
PT P+ P+ P+P P P P P+ T T
Sbjct: 1677 PTT-TPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTT 1720
Score = 62.8 bits (151), Expect = 1e-09
Identities = 45/160 (28%), Positives = 60/160 (37%), Gaps = 27/160 (16%)
Query: 482 PSKPNEIPQQPPPPSSATN--IPSSAPPITSVPRPP----TMPPPVR-----TTVVSAVP 530
PS P PPP ++ + ++ PP T+ P PP T PPP TT S
Sbjct: 1422 PSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPT 1481
Query: 531 VMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSA------------PPIMAPRP 578
P PP + PP + +P P + +PP+ PP P P
Sbjct: 1482 TTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSP 1541
Query: 579 P---PMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEP 615
P P+ PT+ PP P+P P PPP P
Sbjct: 1542 PTTTPITPPTSTTTLPPTT-TPSPPPTTTTTPPPTTTPSP 1580
Score = 62.8 bits (151), Expect = 1e-09
Identities = 48/161 (29%), Positives = 58/161 (36%), Gaps = 28/161 (17%)
Query: 482 PSKPNEIPQQPPP----------PSSATNIPSSAPPITSVPRPPTMP--PPVRTTVVSAV 529
PS P P PP PS T ++ PP T+ P T P PP TT +
Sbjct: 1500 PSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPT 1559
Query: 530 PVMPRPPMASVVRLP-----PGSVIAPMPPII--HAPRINVVPMPPSA-----PPIMAPR 577
PP + P P + P PP I P P PP+ PP P
Sbjct: 1560 TTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPS 1619
Query: 578 PP---PMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEP 615
PP P+ PT+ PP P+P P PPP P
Sbjct: 1620 PPTTTPITPPTSTTTLPPTT-TPSPPPTTTTTPPPTTTPSP 1659
Score = 58.2 bits (139), Expect = 3e-08
Identities = 39/146 (26%), Positives = 54/146 (36%), Gaps = 15/146 (10%)
Query: 482 PSKPNEIPQQPP------PPSSATNIP---SSAPPITSVPRPPTMP---PPVRTTVVSAV 529
PS P P PP PP++ + P ++ PP T+ P PPT PP+ TT
Sbjct: 1618 PSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPP 1677
Query: 530 PVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVP 589
P P+ + P ++ P P + I P S P PPP + T
Sbjct: 1678 TTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTT---TPSPPPTTMTTPSPT 1734
Query: 590 APPVAPVPAPAPMPPVHPPPPMEDEP 615
P P +PP P+ P
Sbjct: 1735 TTPSPPTTTMTTLPPTTTSSPLTTTP 1760
Score = 55.5 bits (132), Expect = 2e-07
Identities = 40/137 (29%), Positives = 54/137 (39%), Gaps = 16/137 (11%)
Query: 485 PNEIPQQPPPPSSATNIPSS--APPITSVPRPP---TMPPPVRTTVVSAVPVMPRPPMAS 539
P PPP ++ T P++ +PP T+ P PP T PP TT S + P PP +
Sbjct: 1636 PPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTT 1695
Query: 540 VVRLPPGSVIAPMPPIIHA--PRINVVPMPP-----SAPPIMAPRPPPMIVPTAFVPAPP 592
+ P P PI P P PP + P P PP + T +P
Sbjct: 1696 MTT--PSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTT--LPPTT 1751
Query: 593 VAPVPAPAPMPPVHPPP 609
+ P+PP PP
Sbjct: 1752 TSSPLTTTPLPPSITPP 1768
Score = 54.3 bits (129), Expect = 4e-07
Identities = 34/121 (28%), Positives = 45/121 (37%), Gaps = 18/121 (14%)
Query: 501 IPSSAPPITSVPRPPTM----------PPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIA 550
I + +PP T+ PPT PP TT P PP+ + PP + +
Sbjct: 1396 ITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPS 1455
Query: 551 PMPPIIHAPRINVVPMPPS---APPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHP 607
P P P PP+ +PP P P PT PP P+P P+ P
Sbjct: 1456 PPISTTTTPPPTTTPSPPTTTPSPPTTTPSP-----PTTTTTTPPPTTTPSPPTTTPITP 1510
Query: 608 P 608
P
Sbjct: 1511 P 1511
Score = 53.9 bits (128), Expect = 5e-07
Identities = 35/129 (27%), Positives = 51/129 (39%), Gaps = 8/129 (6%)
Query: 482 PSKPNEIPQQPPPPSSATNIPSSAP--PITSVPRPPTMP---PPVRTTVVSAVPVMPRPP 536
PS P PP ++ T P++ P PIT+ P PPT P TT S + P
Sbjct: 1657 PSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPS 1716
Query: 537 MASVVRLPPGSVIAPMPPIIHAP---RINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPV 593
+ PP ++ P P +P + +P ++ P+ PP I P F P
Sbjct: 1717 STTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTT 1776
Query: 594 APVPAPAPM 602
P P+
Sbjct: 1777 TPTTPCVPL 1785
Score = 52.8 bits (125), Expect = 1e-06
Identities = 45/159 (28%), Positives = 53/159 (33%), Gaps = 20/159 (12%)
Query: 482 PSKPNEIPQQPPP---PSSATNIP-------SSAPPITSVPRPP--TMPPPVRTTVVSAV 529
PS P PPP PS T P ++ PP T+ PP T PP TT
Sbjct: 1602 PSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPT 1661
Query: 530 PVMPRPPMASVVRLPPGSVIAPMPPIIHAP----RINVVPMPPSAP--PIMAPRPPPMIV 583
P PP+ + PP P PI P P P + P PI P
Sbjct: 1662 TTTPSPPITTTTTPPP--TTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTT 1719
Query: 584 PTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKT 622
+ P P P P PP + TS L T
Sbjct: 1720 TPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTT 1758
Score = 50.4 bits (119), Expect = 6e-06
Identities = 36/116 (31%), Positives = 43/116 (37%), Gaps = 16/116 (13%)
Query: 510 SVPRPPTM---PPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPM 566
+ P PPT PPP TT + P PP + PP + +P P P
Sbjct: 1397 TTPSPPTTTPSPPPTSTTTLPPTTT-PSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPS 1455
Query: 567 PP-----SAPPIMAPRPPPMI-VPTAFVPAPP----VAPVPAPAPMPPVHPP--PP 610
PP + PP P PP P P+PP P P P PP P PP
Sbjct: 1456 PPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPP 1511
Score = 49.7 bits (117), Expect = 1e-05
Identities = 43/145 (29%), Positives = 51/145 (35%), Gaps = 20/145 (13%)
Query: 482 PSKPNEIPQQPPP---PSSATNIPSSAPPITSVPRPP----------TMPPPVRTTVVSA 528
PS P PPP PS T S PPIT+ PP T P P TT+ +
Sbjct: 1641 PSPPPTTTTTPPPTTTPSPPTTTTPS-PPITTTTTPPPTTTPSSPITTTPSPPTTTMTTP 1699
Query: 529 VP-VMPRPPMASVVRLPPGSVIAPMPP--IIHAPRINVVPMPPSAPPIMAPRPPPMIVPT 585
P P P+ + P S P PP + P P PP+ P P P
Sbjct: 1700 SPTTTPSSPITTTT--TPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLP-PTTTSSPL 1756
Query: 586 AFVPAPPVAPVPAPAPMPPVHPPPP 610
P PP P +P P P
Sbjct: 1757 TTTPLPPSITPPTFSPFSTTTPTTP 1781
Score = 47.4 bits (111), Expect = 5e-05
Identities = 35/116 (30%), Positives = 40/116 (34%), Gaps = 17/116 (14%)
Query: 516 TMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPP-----SA 570
T P P TT P PP S LPP + +P P P PP +
Sbjct: 1397 TTPSPPTTT--------PSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTP 1448
Query: 571 PPIMAPRPPPMIVPTAFVPAPPVAP-VPAPAPMPPVHPPPPMEDEPTSKKLKTEDS 625
PP P PP + T P P P P P PP P P T+ T S
Sbjct: 1449 PPTTTPSPP---ISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPS 1501
Score = 41.2 bits (95), Expect = 0.003
Identities = 34/139 (24%), Positives = 45/139 (32%), Gaps = 18/139 (12%)
Query: 492 PPPPSSATNIPSSAPPITSVPRPPTMPP-----PVRTTVVSAVPVMPRPPMASVVRLPPG 546
P P + T P++ P T+ PT P P T + + V P P P G
Sbjct: 4094 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-------PTG 4146
Query: 547 SVIAPMPPIIHAPRINVVPMP-----PSAPPIMAPRP-PPMIVPTAFVPAPPVAPVPAPA 600
+ PI + P P P+ PI P PT PP AP
Sbjct: 4147 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPI 4206
Query: 601 PMPPVHPPPPMEDEPTSKK 619
PPP P + +
Sbjct: 4207 AELTTSNPPPESSTPQTSR 4225
Score = 39.7 bits (91), Expect = 0.010
Identities = 26/95 (27%), Positives = 33/95 (34%), Gaps = 14/95 (14%)
Query: 536 PMASVVRLPPGSVIAPMPPIIHAPRI--NVVPMPPSA-----PPIMAPRPP---PMIVPT 585
PM + P P PP + P PP+ PP P PP P
Sbjct: 1391 PMDKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPP 1450
Query: 586 AFVPAPPVA----PVPAPAPMPPVHPPPPMEDEPT 616
P+PP++ P P P PP P P P+
Sbjct: 1451 TTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPS 1485
Score = 38.1 bits (87), Expect = 0.029
Identities = 31/116 (26%), Positives = 40/116 (34%), Gaps = 23/116 (19%)
Query: 472 PEDDTKEKIGPSKPNEIPQQPPPPS---SATNIPSSAPPITSVPRPPTMPPPVRTTVVSA 528
P T PS P P P + S+T PS P + P P T P P TT+ +
Sbjct: 1689 PSPPTTTMTTPS-PTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTL 1747
Query: 529 VPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVP 584
P P+ + P+PP I PP+ P P VP
Sbjct: 1748 PPTTTSSPLTT----------TPLPPSI---------TPPTFSPFSTTTPTTPCVP 1784
Score = 38.1 bits (87), Expect = 0.029
Identities = 78/364 (21%), Positives = 111/364 (30%), Gaps = 86/364 (23%)
Query: 304 PPPPETPMPPP-----LPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPAS 358
P P TP PP LPPT P + PLPP+ P + T P
Sbjct: 1731 PSPTTTPSPPTTTMTTLPPTTTS-------SPLTTTPLPPSITPPTFSPFSTTTPTTPCV 1783
Query: 359 KMQEHMRIGLLDPRWLEQRDRSIREKQSDDE----VYAPGLDIESSLKQLAERRTDIFGV 414
+ WL+ + + D E V PG S + I +
Sbjct: 1784 PLCNWTG-------WLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPDVPIGQL 1836
Query: 415 EETAIGKK----IGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKAKGL 470
+T + I + E QKP G + I +Q E + + +
Sbjct: 1837 GQTVVCDVSVGLICKNEDQKP----------GGVIPMAFCLNYEINVQ-CCECVTQPTTM 1885
Query: 471 VPEDDTKEKIGPSKPNEIP------QQPPPPSSATNIPSSAP-----PITSVPRP----- 514
T P+ P P P P + T P++ P +T P P
Sbjct: 1886 T----TTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 1941
Query: 515 PTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMP-----PS 569
PT P TT V+ P P G+ PI + P P P+
Sbjct: 1942 PTTTPITTTTTVTPTPT------------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 1989
Query: 570 APPI-----MAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTED 624
PI + P P P T P P+ + P P P PT+ + T
Sbjct: 1990 TTPITTTTTVTPTPTPTGTQT-----PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTT 2043
Query: 625 SLMP 628
++ P
Sbjct: 2044 TVTP 2047
Score = 38.1 bits (87), Expect = 0.029
Identities = 37/155 (23%), Positives = 51/155 (32%), Gaps = 28/155 (18%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P +
Sbjct: 4071 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 4130
Query: 542 RLPPGSVIAPMP-----------PIIHAPRINVVPMP-----PSAPPIMAPRP-PPMIVP 584
+ + + P P PI + P P P+ PI P P
Sbjct: 4131 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 4190
Query: 585 TAFVPAPPVAPVPAP-APMPPVHPPPPMEDEPTSK 618
T PP AP A + +PPP TS+
Sbjct: 4191 TGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSR 4225
Score = 37.0 bits (84), Expect = 0.065
Identities = 39/179 (21%), Positives = 57/179 (31%), Gaps = 37/179 (20%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P +
Sbjct: 4025 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 4084
Query: 542 RLPPGSVIAPMP-----------PIIHAPRINVVPMP-----PSAPPI-----MAPRPPP 580
+ + + P P PI + P P P+ PI + P P P
Sbjct: 4085 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 4144
Query: 581 MIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMPEEEFLRRNKGP 639
T P P+ + P P P PT+ + T ++ P GP
Sbjct: 4145 TGTQT-----PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGP 4197
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 1932 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 1981
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 1982 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2034
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 2035 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2070
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 1955 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2004
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 2005 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2057
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 2058 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2093
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 1978 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2027
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 2028 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2080
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 2081 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2116
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 2001 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2050
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 2051 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2103
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 2104 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2139
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 2024 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2073
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 2074 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2126
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 2127 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2162
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 2047 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2096
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 2097 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2149
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 2150 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2185
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 2070 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2119
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 2120 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2172
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 2173 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2208
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 2093 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2142
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 2143 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2195
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 2196 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2231
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 2116 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2165
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 2166 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2218
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 2219 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2254
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 2139 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2188
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 2189 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2241
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 2242 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2277
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 2162 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2211
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 2212 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2264
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 2265 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2300
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 2185 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2234
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 2235 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2287
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 2288 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2323
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 2208 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2257
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 2258 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2310
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 2311 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2346
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 2231 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2280
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 2281 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2333
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 2334 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2369
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 2254 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2303
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 2304 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2356
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 2357 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2392
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 2277 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2326
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 2327 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2379
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 2380 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2415
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 2300 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2349
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 2350 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2402
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 2403 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2438
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 2323 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2372
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 2373 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2425
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 2426 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2461
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 2346 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2395
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 2396 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2448
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 2449 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2484
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 2369 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2418
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 2419 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2471
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 2472 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2507
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 2392 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2441
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 2442 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2494
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 2495 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2530
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 2415 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2464
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 2465 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2517
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 2518 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2553
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 2438 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2487
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 2488 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2540
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 2541 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2576
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 2461 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2510
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 2511 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2563
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 2564 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2599
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 2484 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2533
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 2534 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2586
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 2587 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2622
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 2507 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2556
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 2557 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2609
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 2610 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2645
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 2530 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2579
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 2580 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2632
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 2633 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2668
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 2553 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2602
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 2603 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2655
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 2656 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2691
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 2576 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2625
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 2626 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2678
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 2679 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2714
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 2599 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2648
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 2649 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2701
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 2702 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2737
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 2622 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2671
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 2672 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2724
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 2725 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2760
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 2645 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2694
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 2695 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2747
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 2748 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2783
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 2668 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2717
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 2718 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2770
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 2771 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2806
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 2691 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2740
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 2741 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2793
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 2794 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2829
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 2714 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2763
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 2764 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2816
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 2817 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2852
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 2737 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2786
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 2787 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2839
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 2840 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2875
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 2760 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2809
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 2810 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2862
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 2863 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2898
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 2783 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2832
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 2833 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2885
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 2886 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2921
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 2806 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2855
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 2856 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2908
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 2909 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2944
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 2829 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2878
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 2879 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2931
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 2932 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2967
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 2852 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2901
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 2902 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2954
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 2955 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2990
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 2875 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2924
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 2925 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2977
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 2978 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3013
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 2898 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2947
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 2948 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3000
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 3001 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3036
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 2921 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2970
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 2971 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3023
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 3024 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3059
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 2944 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2993
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 2994 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3046
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 3047 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3082
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 2967 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3016
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 3017 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3069
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 3070 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3105
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 2990 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3039
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 3040 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3092
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 3093 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3128
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 3013 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3062
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 3063 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3115
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 3116 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3151
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 3036 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3085
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 3086 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3138
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 3139 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3174
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 3059 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3108
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 3109 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3161
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 3162 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3197
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 3082 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3131
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 3132 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3184
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 3185 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3220
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 3105 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3154
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 3155 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3207
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 3208 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3243
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 3128 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3177
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 3178 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3230
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 3231 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3266
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 3151 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3200
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 3201 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3253
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 3254 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3289
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 3174 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3223
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 3224 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3276
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 3277 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3312
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 3197 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3246
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 3247 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3299
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 3300 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3335
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 3220 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3269
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 3270 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3322
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 3323 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3358
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 3243 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3292
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 3293 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3345
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 3346 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3381
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 3266 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3315
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 3316 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3368
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 3369 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3404
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 3289 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3338
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 3339 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3391
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 3392 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3427
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 3312 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3361
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 3362 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3414
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 3415 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3450
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 3335 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3384
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 3385 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3437
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 3438 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3473
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 3358 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3407
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 3408 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3460
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 3461 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3496
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 3381 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3430
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 3431 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3483
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 3484 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3519
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 3404 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3453
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 3454 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3506
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 3507 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3542
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 3427 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3476
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 3477 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3529
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 3530 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3565
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 3450 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3499
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 3500 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3552
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 3553 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3588
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 3473 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3522
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 3523 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3575
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 3576 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3611
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 3496 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3545
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 3546 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3598
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 3599 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3634
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 3519 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3568
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 3569 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3621
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 3622 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3657
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 3542 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3591
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 3592 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3644
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 3645 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3680
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 3565 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3614
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 3615 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3667
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 3668 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3703
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 3588 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3637
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 3638 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3690
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 3691 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3726
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 3611 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3660
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 3661 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3713
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 3714 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3749
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 3634 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3683
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 3684 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3736
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 3737 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3772
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 3657 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3706
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 3707 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3759
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 3760 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3795
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 3680 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3729
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 3730 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3782
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 3783 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3818
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 3703 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3752
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 3753 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3805
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 3806 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3841
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 3726 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3775
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 3776 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3828
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 3829 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3864
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 3749 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3798
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 3799 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3851
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 3852 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3887
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 3772 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3821
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 3822 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3874
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 3875 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3910
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 3795 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3844
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 3845 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3897
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 3898 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3933
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 3818 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3867
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 3868 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3920
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 3921 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3956
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 3841 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3890
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 3891 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3943
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 3944 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3979
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 3864 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3913
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 3914 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3966
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 3967 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 4002
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 3887 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3936
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 3937 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3989
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 3990 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 4025
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 3910 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3959
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 3960 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 4012
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 4013 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 4048
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 3933 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3982
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 3983 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 4035
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 4036 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 4071
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 3956 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 4005
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 4006 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 4058
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 4059 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 4094
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 3979 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 4028
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 4029 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 4081
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 4082 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 4117
Score = 36.6 bits (83), Expect = 0.085
Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P
Sbjct: 4002 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 4051
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 591
P G+ PI + P P P+ PI + P P P T P
Sbjct: 4052 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 4104
Query: 592 PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P+ + P P P PT+ + T ++ P
Sbjct: 4105 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 4140
Score = 33.1 bits (74), Expect = 0.94
Identities = 33/144 (22%), Positives = 52/144 (36%), Gaps = 31/144 (21%)
Query: 492 PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 541
P P + T P++ P +T P P PT P TT V+ P P +
Sbjct: 4140 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 4195
Query: 542 RLPPGSVIAPM--------PPIIHAPRINVVPMPP--SAPPIMAPRPPPMIVPTAFVPAP 591
P + AP+ PP P+ + P + +++ PP + + + P+
Sbjct: 4196 GPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPST 4255
Query: 592 PVAPVP-------APAPMPPVHPP 608
P AP +P P PP
Sbjct: 4256 PTAPTTTSGGHTLSPPPSTTTSPP 4279
Score = 31.2 bits (69), Expect = 3.6
Identities = 16/52 (30%), Positives = 20/52 (38%), Gaps = 6/52 (11%)
Query: 2 PAGPVQAVPPPP------PVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPP 47
P+ P PPP P T P PT + + PS P+ PPP
Sbjct: 1399 PSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPP 1450
Score = 31.2 bits (69), Expect = 3.6
Identities = 17/44 (38%), Positives = 18/44 (40%), Gaps = 5/44 (11%)
Query: 304 PPPPETPMPP---PLPP--TPDQVIVRKDYDPKASKPLPPAPAP 342
PPP TP PP P PP TP P + P PP P
Sbjct: 1464 PPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTP 1507
Score = 31.2 bits (69), Expect = 3.6
Identities = 14/43 (32%), Positives = 16/43 (37%)
Query: 5 PVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPP 47
P P PP T P PT + + PS P PPP
Sbjct: 1572 PPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPP 1614
Score = 30.8 bits (68), Expect = 4.6
Identities = 34/133 (25%), Positives = 48/133 (36%), Gaps = 22/133 (16%)
Query: 492 PPPPSSA--TNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVI 549
PPP SS T+ +S+P S T+PP + T +A P P P + G +
Sbjct: 4214 PPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS-TAPPSTPTAPTTT----SGGHTL 4268
Query: 550 APMPPIIHAPRINVVPMPPSAPPI-----MAPRPPPMIVPTAFVPAPPVAPVPAPAPMPP 604
+P P + PP P + P P V T A P P P P
Sbjct: 4269 SPPP--------STTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSA--WTPTPTPLSTPS 4318
Query: 605 VHPPPPMEDEPTS 617
+ + P+S
Sbjct: 4319 IIRTTGLRPYPSS 4331
Score = 30.4 bits (67), Expect = 6.1
Identities = 17/53 (32%), Positives = 19/53 (35%), Gaps = 7/53 (13%)
Query: 304 PPPPETPMPP-------PLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSP 349
PPP TP PP P TP I P + P PP P +P
Sbjct: 1432 PPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTP 1484
Score = 30.0 bits (66), Expect = 7.9
Identities = 23/67 (34%), Positives = 26/67 (38%), Gaps = 12/67 (17%)
Query: 304 PPPPETPMPP----PLPP---TPDQVIVRKDYDPKASKPLPP-----APAPDEYLVSPIT 351
PPP TP PP P PP T P + P PP P+P SPIT
Sbjct: 1651 PPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPIT 1710
Query: 352 GEKIPAS 358
P+S
Sbjct: 1711 TTTTPSS 1717
>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sapiens]
Length = 2462
Score = 70.9 bits (172), Expect = 4e-12
Identities = 101/431 (23%), Positives = 153/431 (35%), Gaps = 41/431 (9%)
Query: 254 ESEEVEMEVESDEEDDKQEKAEEPPSQLDQDTQVQDMDEGSDDEEEGQKVPPPPET---P 310
E EE+E S E++ E+AE + DT+ ++ GQ P PP T
Sbjct: 701 EDEEMEASGVSGNEEEMVEEAEATVNN-SSDTESIPSPHTEAAKDTGQNGPKPPATLGAD 759
Query: 311 MPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKMQEHMRIGLLD 370
PPP PPTP + +P + AP P SP + + +E
Sbjct: 760 GPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPP 819
Query: 371 PRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAE----RRTDIFGVEETAIGKKIGEE 426
E++ E+ + D A ++S + AE + D E TA G + E
Sbjct: 820 VEEGEEQKPPAAEELAVDTGKAEE-PVKSECTEEAEEGPAKGKDAEAAEATAEG-ALKAE 877
Query: 427 EIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKAKGLVPEDDTKEKIGPSKPN 486
+ + + T SG+ + +A + ++ E K + L P G + N
Sbjct: 878 KKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRAN 937
Query: 487 EIPQQP------------PPPSSATNI--PSSAPPITSVPRPPTMPPPVRTTVVSAVPVM 532
PQ+P PP T + P + P PP PPP S P
Sbjct: 938 ASPQKPLDLKQLKQRAAAIPPIQVTKVHEPPREDAAPTKPAPPAPPPPQNLQPESDAPQQ 997
Query: 533 P--RPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAP----PIMAPRPPPMIV--- 583
P P S PP A P A +P P + P PP ++
Sbjct: 998 PGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVPPREVIKAS 1057
Query: 584 -----PTAFVPAPPVAPVPAPA--PMPPVHPPPPMEDEPTSKKLKTEDSLMPEEEFLRRN 636
P+AF APP P+P PV P PP P + + E + +
Sbjct: 1058 PHAPDPSAFSYAPPGHPLPLGLHDTARPVLPRPPTISNPPPLISSAKHPSVLERQIGAIS 1117
Query: 637 KGPVSIKVQVP 647
+G +S+++ VP
Sbjct: 1118 QG-MSVQLHVP 1127
Score = 48.9 bits (115), Expect = 2e-05
Identities = 94/473 (19%), Positives = 183/473 (38%), Gaps = 91/473 (19%)
Query: 114 RQFLTQLMQKEQRNYQFDFLRPQHSLFNYFTKLVEQYTKILIPPKGLFSKLKKEAENPRE 173
RQ + ++E+ ++ F++ + F +E+ T + L+ L K+ EN +
Sbjct: 426 RQVMNMWSEQEKETFREKFMQHPKN-FGLIASFLERKT---VAECVLYYYLTKKNENYKS 481
Query: 174 VLDQVCYRVEWAKFQERERKKEEEEKEKERVAYAQIDWHDFVVVETVDFQPNEQGNFPPP 233
++ + ++ R + ++++++++++ Q +Q P
Sbjct: 482 LVRR--------SYRRRGKSQQQQQQQQQQ-------------------QQQQQQQPMPR 514
Query: 234 TTPEELGARILIQERYEKFGESEEVEMEVESDEEDDKQEKAEEPPSQLDQDTQVQDMDEG 293
++ EE ++ EK E EE + EVE+D+ED +EK + DT +D DE
Sbjct: 515 SSQEEKD-----EKEKEKEAEKEEEKPEVENDKEDLLKEKTD--------DTSGEDNDEK 561
Query: 294 SDDEEEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGE 353
+G+K ++ + P+ S L + S T E
Sbjct: 562 EAVASKGRKTANSQGRRKGRITRSMANEANSEEAITPQQSAELASMELNES---SRWTEE 618
Query: 354 KIPASK--MQEHMRIGLLDPRWLEQRDRS--------IREKQSDDEV---YAPGLDIESS 400
++ +K + EH R R + + S +++Q+ DE+ + ++ E +
Sbjct: 619 EMETAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQNLDEILQQHKLKMEKERN 678
Query: 401 LKQLAERRTDIFGVEETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQ 460
++ +++ EE A + +EE++ G SG+ + A+A +
Sbjct: 679 ARR-KKKKAPAAASEEAAFPPVVEDEEMEA-------SGVSGNEEEMVEEAEATVNNSSD 730
Query: 461 IEAIHKAKGLVPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPP 520
E+I P + + G + P PP + + P PP P P +P P
Sbjct: 731 TESIPS-----PHTEAAKDTGQNGPK------PPATLGADGPPPGPP---TPPPEDIPAP 776
Query: 521 VRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPI 573
T S P PP A P S AP PP++ P+ +APP+
Sbjct: 777 TEPTPASEATGAPTPPPA------PPSPSAP-PPVV--PKEEKEEETAAAPPV 820
Score = 37.4 bits (85), Expect = 0.050
Identities = 78/354 (22%), Positives = 122/354 (34%), Gaps = 83/354 (23%)
Query: 307 PETP-MPPPLPPTPDQVIVRKDYDPKASKPL-------PPAPAPDEYLVSPITGEKIPAS 358
P P + PP P TP + R Y P A +P P +P +L P T +S
Sbjct: 1729 PHLPVLVPPTPGTPATAMDRLAYLPTAPQPFSSRHSSSPLSPGGPTHLTKPTT----TSS 1784
Query: 359 KMQEHMRIGLLDPRWLEQRDRSIREKQSDDE---VYAPGLDIESSLKQLAERRTDIFGVE 415
+E R D +R++SI + E ++ PG + S G
Sbjct: 1785 SERERDRDRERDRD--REREKSILTSTTTVEHAPIWRPGTEQSS-------------GSS 1829
Query: 416 ETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKA--KGLVPE 473
++ G G +P HS RTQ A LQ++ +H KG++
Sbjct: 1830 GSSGG---GGGSSSRPASHSHAHQHSPISPRTQDA------LQQRPSVLHNTGMKGIITA 1880
Query: 474 DDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVM- 532
+P P+ + +S+P + PP P+ T+ P +
Sbjct: 1881 ----------------VEPSTPTVLRSTSTSSPVRPAATFPPATHCPLGGTLDGVYPTLM 1924
Query: 533 ---------PRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIV 583
PR R G PP + P++ P P P++
Sbjct: 1925 EPVLLPKEAPRVARPERPRADTGHAFLAKPPARSG-------LEPASSPSKGSEPRPLVP 1977
Query: 584 PT------AFVPAPPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMPEEE 631
P A PA +AP A +P PP PP +P +K +++ + E E
Sbjct: 1978 PVSGHATIARTPAKNLAPHHA-SPDPPA--PPASASDPHREKTQSKPFSIQELE 2028
Score = 30.4 bits (67), Expect = 6.1
Identities = 19/81 (23%), Positives = 35/81 (43%), Gaps = 2/81 (2%)
Query: 254 ESEEVEMEVESDEEDDKQEKAEEPPSQLDQDTQVQDMDEGSDDEEEGQKVPPPPETPMPP 313
E E V + +E ++ + + ++Q Q+ + + EE PP PE P+ P
Sbjct: 159 ELELVPPRLSKEELIQNMDRVDREITMVEQ--QISKLKKKQQQLEEEAAKPPEPEKPVSP 216
Query: 314 PLPPTPDQVIVRKDYDPKASK 334
P + + +V+ YD K
Sbjct: 217 PPIESKHRSLVQIIYDENRKK 237
Score = 30.0 bits (66), Expect = 7.9
Identities = 17/48 (35%), Positives = 19/48 (39%), Gaps = 4/48 (8%)
Query: 2 PAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPPEV 49
P GP P P PTEP +E + AP P PPP V
Sbjct: 762 PPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSA----PPPVV 805
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 70.5 bits (171), Expect = 5e-12
Identities = 84/343 (24%), Positives = 121/343 (35%), Gaps = 54/343 (15%)
Query: 303 VPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPIT-----GEKIPA 357
VPPPP P+PPP PP A P PP+ P S + G
Sbjct: 3 VPPPPPPPLPPPPPPLG------------APPPPPPSAPPVSTDTSSLRRADPKGRSALL 50
Query: 358 SKMQEHMR---IGLLDPRWLEQRDRSI-REKQSDDEVYAPGLDIESSLKQLAERRTDIF- 412
+ +Q+ R + ++ R Q + S K+ G +L L +
Sbjct: 51 ADIQQGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLR 110
Query: 413 --GVEETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKAKGL 470
G + A GK + P ++ SG + N + EA A+
Sbjct: 111 PAGQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTS-----EAHGAARTA 165
Query: 471 VPEDDTKEKIGPSKPNEIPQQPPP-PSSAT---------------NIPSSAPPITSVPRP 514
P + P+ P P PPP PSS+ N+P APP+ P P
Sbjct: 166 PPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPP 225
Query: 515 PTMPPPVRTTVVSAVPVMPRP---PMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAP 571
P PPP + V+ P + + LPP P+ P P + P P+
Sbjct: 226 PPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQD 285
Query: 572 PIMAPRPPPMI------VPTAFVPAPPVAPVPAPAPMPPVHPP 608
P PPP + P A +PAPP+ V + + PP PP
Sbjct: 286 AQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPP 328
Score = 49.3 bits (116), Expect = 1e-05
Identities = 44/168 (26%), Positives = 59/168 (35%), Gaps = 36/168 (21%)
Query: 482 PSKPNEIPQQPP-PPSSATNIPSSAPPITSVPRPPTMPP------------------PVR 522
P P P PP PP+S + + P + + PP PP P +
Sbjct: 225 PPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQ 284
Query: 523 TTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMI 582
P P PP AS P S+ AP P +++ P+PP +P AP P
Sbjct: 285 DAQEPPAPPPPLPPYASCS--PRASLPAPPLPGVNSSSETPPPLPPKSPSFQAP---PQK 339
Query: 583 VPTAFVPAPPVAPVPAPAPMPPVH------------PPPPMEDEPTSK 618
+PAPP P P H PP P PT++
Sbjct: 340 AGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSPTTE 387
Score = 41.6 bits (96), Expect = 0.003
Identities = 47/201 (23%), Positives = 65/201 (32%), Gaps = 71/201 (35%)
Query: 488 IPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGS 547
+P PPPP +P PP+ + P PP PPV T S P+ A + + G+
Sbjct: 3 VPPPPPPP-----LPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGT 57
Query: 548 VIAPMPPIIH--APRINV----------------VPMPPSAPPIMA-------------- 575
+ + I AP+I PP+ + A
Sbjct: 58 RLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDV 117
Query: 576 ---------------PRPPPMIVPTAFVP------------------APPVAPVPAPAPM 602
PR P + +P APP VPAP P
Sbjct: 118 AGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPP 177
Query: 603 PPVHPPPPMEDE-PTSKKLKT 622
P PPPP+ P+S +KT
Sbjct: 178 TPPPPPPPLPPPLPSSSPIKT 198
Score = 35.0 bits (79), Expect = 0.25
Identities = 19/45 (42%), Positives = 22/45 (48%), Gaps = 1/45 (2%)
Query: 3 AGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPP 47
A PV PPPPP P P P AS D A KP + ++ PP
Sbjct: 216 APPVPCAPPPPPPPPPPTPPPLPPASVLSDKA-VKPQLAPLHLPP 259
Score = 34.7 bits (78), Expect = 0.32
Identities = 15/32 (46%), Positives = 19/32 (59%), Gaps = 3/32 (9%)
Query: 564 VPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAP 595
+P+PP PP + P PPP+ P P PP AP
Sbjct: 1 MPVPPPPPPPLPPPPPPLGAPP---PPPPSAP 29
Score = 34.3 bits (77), Expect = 0.42
Identities = 15/38 (39%), Positives = 21/38 (55%), Gaps = 2/38 (5%)
Query: 588 VPAPPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDS 625
+P PP P P P P PP+ PPP P++ + T+ S
Sbjct: 1 MPVPPPPPPPLPPPPPPLGAPPP--PPPSAPPVSTDTS 36
Score = 32.0 bits (71), Expect = 2.1
Identities = 17/44 (38%), Positives = 21/44 (47%), Gaps = 10/44 (22%)
Query: 576 PRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPP--PPMEDEPTS 617
P PPP P PP+ P P P PP PP PP+ + +S
Sbjct: 2 PVPPP--------PPPPLPPPPPPLGAPPPPPPSAPPVSTDTSS 37
Score = 32.0 bits (71), Expect = 2.1
Identities = 19/67 (28%), Positives = 25/67 (37%), Gaps = 10/67 (14%)
Query: 293 GSDDEEEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITG 352
G+ E G PP +P P PPTP P PLPP + +P+
Sbjct: 153 GNTSEAHGAARTAPPRPNVPAPPPPTP----------PPPPPPLPPPLPSSSPIKTPLVS 202
Query: 353 EKIPASK 359
P +K
Sbjct: 203 PPGPLTK 209
>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sapiens]
Length = 2524
Score = 70.1 bits (170), Expect = 7e-12
Identities = 104/459 (22%), Positives = 160/459 (34%), Gaps = 42/459 (9%)
Query: 225 NEQGNFPPPTTPEELGARILIQERYEKFGESEEVEMEVESDEEDDKQEKAEEPPSQLDQD 284
+E+ FPP EE+ A + E E+E + S E + E + D
Sbjct: 691 SEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEALHA---SGNEVPRGECSGPATVNNSSD 747
Query: 285 TQVQDMDEGSDDEEEGQKVPPPPET---PMPPPLPPTPDQVIVRKDYDPKASKPLPPAPA 341
T+ ++ GQ P PP T PPP PPTP + +P + AP
Sbjct: 748 TESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPT 807
Query: 342 PDEYLVSPITGEKIPASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSL 401
P SP + + +E E++ E+ + D A ++S
Sbjct: 808 PPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAVDTGKAEE-PVKSEC 866
Query: 402 KQLAE----RRTDIFGVEETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITL 457
+ AE + D E TA G + E+ + + T SG+ + +A +
Sbjct: 867 TEEAEEGPAKGKDAEAAEATAEG-ALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADE 925
Query: 458 QEQIEAIHKAKGLVPEDDTKEKIGPSKPNEIPQQP-------------PPPSSATNIPSS 504
++ E K + L P G + N PQ+P PP + + P
Sbjct: 926 VDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRAAAIPPIVTKVHEPPR 985
Query: 505 APPITSVPRPPTMPPPVRTTVVSAVPVMP--RPPMASVVRLPPGSVIAPMPPIIHAPRIN 562
+ P PP PPP S P P P S PP A P A
Sbjct: 986 EDAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAE 1045
Query: 563 VVPMPPSAP----PIMAPRPPPMIV--------PTAFVPAPPVAPVPAPA--PMPPVHPP 608
+P P + P PP ++ P+AF APP P+P PV P
Sbjct: 1046 AQKLPGDPPCWTSGLPFPVPPREVIKASPHAPDPSAFSYAPPGHPLPLGLHDTARPVLPR 1105
Query: 609 PPMEDEPTSKKLKTEDSLMPEEEFLRRNKGPVSIKVQVP 647
PP P + + E + ++G +S+++ VP
Sbjct: 1106 PPTISNPPPLISSAKHPSVLERQIGAISQG-MSVQLHVP 1143
Score = 47.8 bits (112), Expect = 4e-05
Identities = 103/498 (20%), Positives = 189/498 (37%), Gaps = 104/498 (20%)
Query: 114 RQFLTQLMQKEQRNYQFDFLRPQHSLFNYFTKLVEQYTKILIPPKGLFSKLKKEAENPRE 173
RQ + ++E+ ++ F++ + F +E+ T + L+ L K+ EN +
Sbjct: 426 RQVMNMWSEQEKETFREKFMQHPKN-FGLIASFLERKT---VAECVLYYYLTKKNENYKS 481
Query: 174 VLDQVCYRVEWAKFQERERKKEEEEKEKERVAYAQIDWHDFVVVETVDFQPNEQGNFPPP 233
++ + ++ R + ++++++++++ Q +Q P
Sbjct: 482 LVRR--------SYRRRGKSQQQQQQQQQQ-------------------QQQQQQQPMPR 514
Query: 234 TTPEELGARILIQERYEKFGESEEVEMEVESDEEDDKQEKAEEPPSQLDQDTQVQDMDEG 293
++ EE ++ EK E EE + EVE+D+ED +EK + DT +D DE
Sbjct: 515 SSQEEKD-----EKEKEKEAEKEEEKPEVENDKEDLLKEKTD--------DTSGEDNDEK 561
Query: 294 SDDEEEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGE 353
+G+K ++ + P+ S L + S T E
Sbjct: 562 EAVASKGRKTANSQGRRKGRITRSMANEANSEEAITPQQSAELASMELNES---SRWTEE 618
Query: 354 KIPASK--MQEHMRIGLLDPRWLEQRDRS--------IREKQSDDEV---YAPGLDIESS 400
++ +K + EH R R + + S +++Q+ DE+ + ++ E +
Sbjct: 619 EMETAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQNLDEILQQHKLKMEKERN 678
Query: 401 LKQLAERRTDIFGVEETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQ 460
++ +++ EE A + +EE++ G SG+ + E+
Sbjct: 679 ARR-KKKKAPAAASEEAAFPPVVEDEEMEA-------SGVSGNEEE----------MVEE 720
Query: 461 IEAIHKAKGLVPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPP 520
EA+H + VP + GP+ N S +IPS P T + P
Sbjct: 721 AEALHASGNEVPRGECS---GPATVNN-------SSDTESIPS---PHTEAAKDTGQNGP 767
Query: 521 VRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPP 580
+ A P PP PP + AP P A P PP APP +P PP
Sbjct: 768 KPPATLGADGPPPGPPTP-----PPEDIPAPTEP-TPASEATGAPTPPPAPP--SPSAPP 819
Query: 581 MIVP-----TAFVPAPPV 593
+VP APPV
Sbjct: 820 PVVPKEEKEEETAAAPPV 837
Score = 37.4 bits (85), Expect = 0.050
Identities = 78/354 (22%), Positives = 122/354 (34%), Gaps = 83/354 (23%)
Query: 307 PETP-MPPPLPPTPDQVIVRKDYDPKASKPL-------PPAPAPDEYLVSPITGEKIPAS 358
P P + PP P TP + R Y P A +P P +P +L P T +S
Sbjct: 1745 PHLPVLVPPTPGTPATAMDRLAYLPTAPQPFSSRHSSSPLSPGGPTHLTKPTT----TSS 1800
Query: 359 KMQEHMRIGLLDPRWLEQRDRSIREKQSDDE---VYAPGLDIESSLKQLAERRTDIFGVE 415
+E R D +R++SI + E ++ PG + S G
Sbjct: 1801 SERERDRDRERDRD--REREKSILTSTTTVEHAPIWRPGTEQSS-------------GSS 1845
Query: 416 ETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKA--KGLVPE 473
++ G G +P HS RTQ A LQ++ +H KG++
Sbjct: 1846 GSSGG---GGGSSSRPASHSHAHQHSPISPRTQDA------LQQRPSVLHNTGMKGIITA 1896
Query: 474 DDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVM- 532
+P P+ + +S+P + PP P+ T+ P +
Sbjct: 1897 ----------------VEPSTPTVLRSTSTSSPVRPAATFPPATHCPLGGTLDGVYPTLM 1940
Query: 533 ---------PRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIV 583
PR R G PP + P++ P P P++
Sbjct: 1941 EPVLLPKEAPRVARPERPRADTGHAFLAKPPARSG-------LEPASSPSKGSEPRPLVP 1993
Query: 584 PT------AFVPAPPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMPEEE 631
P A PA +AP A +P PP PP +P +K +++ + E E
Sbjct: 1994 PVSGHATIARTPAKNLAPHHA-SPDPPA--PPASASDPHREKTQSKPFSIQELE 2044
Score = 30.4 bits (67), Expect = 6.1
Identities = 19/81 (23%), Positives = 35/81 (43%), Gaps = 2/81 (2%)
Query: 254 ESEEVEMEVESDEEDDKQEKAEEPPSQLDQDTQVQDMDEGSDDEEEGQKVPPPPETPMPP 313
E E V + +E ++ + + ++Q Q+ + + EE PP PE P+ P
Sbjct: 159 ELELVPPRLSKEELIQNMDRVDREITMVEQ--QISKLKKKQQQLEEEAAKPPEPEKPVSP 216
Query: 314 PLPPTPDQVIVRKDYDPKASK 334
P + + +V+ YD K
Sbjct: 217 PPIESKHRSLVQIIYDENRKK 237
Score = 30.0 bits (66), Expect = 7.9
Identities = 17/48 (35%), Positives = 19/48 (39%), Gaps = 4/48 (8%)
Query: 2 PAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPPEV 49
P GP P P PTEP +E + AP P PPP V
Sbjct: 779 PPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSA----PPPVV 822
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 70.1 bits (170), Expect = 7e-12
Identities = 48/164 (29%), Positives = 67/164 (40%), Gaps = 7/164 (4%)
Query: 471 VPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSA-PPITSVPRPPTMPPPVRTTVVSAV 529
+P + E+ +K ++ + SA + P A P TS P P + P V
Sbjct: 1377 LPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAP---AAAVPGP 1433
Query: 530 PVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPI---MAPRPPPMIVPTA 586
P +P P A+ P ++ PP P P PP PP P PPP++ PT
Sbjct: 1434 PPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTP 1493
Query: 587 FVPAPPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMPEE 630
P PP P P P MP PPPP P + + + PE+
Sbjct: 1494 SSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPED 1537
Score = 69.7 bits (169), Expect = 9e-12
Identities = 56/175 (32%), Positives = 69/175 (39%), Gaps = 28/175 (16%)
Query: 448 QQAAQANITLQEQIEAIHKAKGLVPEDDTKEKIGPSKPN-----EIPQQPPPPS--SATN 500
+ + N LQE I + A P K+ P P +P PP P SA +
Sbjct: 1385 EDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANS 1444
Query: 501 IPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPR 560
+ PP+ PPT PPP T P P PP PP P PP +
Sbjct: 1445 NGTPEPPLLEEKPPPT-PPPAPTPQ----PQPPPPP-------PPPQPALPSPPPL---- 1488
Query: 561 INVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEP 615
V P P S PP P PPP +P+ P PP P AP PP P P ++P
Sbjct: 1489 --VAPTPSSPPPPPLPPPPPPAMPS---PPPPPPPAAAPLAAPPEEPAAPSPEDP 1538
Score = 43.5 bits (101), Expect = 7e-04
Identities = 22/57 (38%), Positives = 30/57 (52%), Gaps = 3/57 (5%)
Query: 300 GQKVPPPPETPMPPPLPPTPDQVIVRK--DYDPKASKPLPPAPAPDEYLVSPITGEK 354
G PPP+ P PPP P TP++ K + P+ + P PPAP L+ P+ EK
Sbjct: 1687 GGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKPS-LLRPVEKEK 1742
Score = 40.4 bits (93), Expect = 0.006
Identities = 54/253 (21%), Positives = 88/253 (34%), Gaps = 18/253 (7%)
Query: 303 VPPPPETPMPPPLPPTPDQVIVRKDYDPK-ASKPL------PPAPAPDEYLVSPITGEKI 355
V P P +P PPPLPP P + P A+ PL P AP+P++ + P T
Sbjct: 1489 VAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPEL-PDTRPLH 1547
Query: 356 PASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGVE 415
A K + G D E I ++ + + A + Q I+ V+
Sbjct: 1548 LAKKQETAAVCGETDEEAGESGGEGIFRERDEFVIRAEDIPSLKLALQTGREPPPIWRVQ 1607
Query: 416 ETAIGK-----KIGEEEIQKPEEKVTWDGHSGSM-ARTQQAAQANITLQEQIEAIHKAKG 469
+ + K K G+ + + + G + + R N+ ++ + +
Sbjct: 1608 KALLQKFTPEIKDGQRQFCATSNYLGYFGDAKNRYQRLYVKFLENVNKKDYVRVCARKPW 1667
Query: 470 LVPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAV 529
P + P PP A + PP P T P T +A+
Sbjct: 1668 HRPPVPVRRSGQAKNPVSAGGSSAPPPKAP----APPPKPETPEKTTSEKPPEQTPETAM 1723
Query: 530 PVMPRPPMASVVR 542
P P P S++R
Sbjct: 1724 PEPPAPEKPSLLR 1736
Score = 38.9 bits (89), Expect = 0.017
Identities = 25/86 (29%), Positives = 35/86 (40%), Gaps = 29/86 (33%)
Query: 572 PIMAPRPPPMIVPTAFVPAPPVAPVP---------------APAPMPPVHPPPP------ 610
P++ P PPP ++P+ AP +P AP P PP PPPP
Sbjct: 791 PLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQL 850
Query: 611 --------MEDEPTSKKLKTEDSLMP 628
+E S +L+ E+SL P
Sbjct: 851 EAHLRSHGLEPAAPSPRLRPEESLDP 876
Score = 35.8 bits (81), Expect = 0.14
Identities = 29/99 (29%), Positives = 34/99 (34%), Gaps = 9/99 (9%)
Query: 250 EKFGESEEVEMEVESDEED------DKQEKAEEPPSQLDQDTQVQDMDEGSDDEEEGQKV 303
E+ + E SDEED D QE S LD D + D G +
Sbjct: 1368 EELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPD---GPPL 1424
Query: 304 PPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAP 342
P P PPPLP P P + PP P P
Sbjct: 1425 APAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPP 1463
Score = 35.4 bits (80), Expect = 0.19
Identities = 66/303 (21%), Positives = 98/303 (32%), Gaps = 72/303 (23%)
Query: 299 EGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKP-LPPAPAPDEYLVSPITGEKIPA 357
+G PPPP P PPP+P + + +P A P L P + D P
Sbjct: 830 DGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLD------------PP 877
Query: 358 SKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGVEET 417
MQE +G L+P D + S+ + A S A R + +
Sbjct: 878 GAMQE--LLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSI--- 932
Query: 418 AIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQI---EAIHKAKGLVPED 474
+ + + EE+ + T++E A K PED
Sbjct: 933 -----CFPDSLLQDEERSFFP-----------------TMEEMFGGGAADDYGKAGPPED 970
Query: 475 DTKEKIG----PSKPNEIPQQPPPPSSATNIPSSAPPITSVP-RPPTMPPPVRTTVVSAV 529
+ K G P P P P P A+ P + P +PP +P + V+A
Sbjct: 971 EGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELP-----STVNAE 1025
Query: 530 PVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVP 589
P+ +++ P P PP PP PP A P + F
Sbjct: 1026 PL-------GLIQSGPHQAAPPPPP------------PPPPPPAPASEPKGGLTSPIFCS 1066
Query: 590 APP 592
P
Sbjct: 1067 TKP 1069
Score = 35.4 bits (80), Expect = 0.19
Identities = 21/54 (38%), Positives = 23/54 (42%), Gaps = 8/54 (14%)
Query: 297 EEEGQKVPPPPETPMP-PPLPPTPDQ-------VIVRKDYDPKASKPLPPAPAP 342
EE+ PPP TP P PP PP P Q +V PLPP P P
Sbjct: 1454 EEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPP 1507
Score = 34.7 bits (78), Expect = 0.32
Identities = 25/85 (29%), Positives = 30/85 (35%)
Query: 301 QKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKM 360
Q PPPP P P LP P V P P PP PA P A+
Sbjct: 1468 QPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPP 1527
Query: 361 QEHMRIGLLDPRWLEQRDRSIREKQ 385
+E DP + R + +KQ
Sbjct: 1528 EEPAAPSPEDPELPDTRPLHLAKKQ 1552
Score = 33.9 bits (76), Expect = 0.55
Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 12/68 (17%)
Query: 3 AGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPPEVRNIVDKTASF--V 60
+GP QA PPPPP P P P E P + I+ + + ++ KT+SF +
Sbjct: 1032 SGPHQAAPPPPPPPPPPPAPASE---------PKGGLTSPIFCSTKPKKLL-KTSSFHLL 1081
Query: 61 ARNGPEFE 68
R P F+
Sbjct: 1082 RRRDPPFQ 1089
Score = 33.5 bits (75), Expect = 0.72
Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 4/46 (8%)
Query: 2 PAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPP 47
PA Q PPPPP P +P P+ + S+P P + PPP
Sbjct: 1463 PAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPL----PPP 1504
Score = 32.0 bits (71), Expect = 2.1
Identities = 36/134 (26%), Positives = 50/134 (37%), Gaps = 27/134 (20%)
Query: 495 PSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMP-RPPMASVV-------RLPPG 546
P+S + P P S+ PP PP ++S V+ +P A V RL G
Sbjct: 154 PASFGSRPFPVPSSLSLQDPPFSPPA--NGLLSPHDVLHLKPSQAPTVPSSLGFERLAGG 211
Query: 547 SVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAF--VPAPPVAPVPAPAPMPP 604
V+ P + PP P P PPP +PT F + + A A P
Sbjct: 212 GVLGPAG-------LGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQ 264
Query: 605 VH--------PPPP 610
++ PPPP
Sbjct: 265 LYNFSGAAPGPPPP 278
Score = 30.4 bits (67), Expect = 6.1
Identities = 25/90 (27%), Positives = 32/90 (35%), Gaps = 17/90 (18%)
Query: 502 PSSAPPITSVPRPPTMPPPVR-----------TTVVSAVPVMPRPPMASVVRLPPGSVIA 550
P+ PP P PP PPP R ++ +A P + + PG
Sbjct: 221 PAQTPPYR--PGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPG---- 274
Query: 551 PMPPIIHAPRINVVPMPPSAPPIMAPRPPP 580
P PP PR + V P P PPP
Sbjct: 275 PPPPERALPRQDTVIKHYQRPASAQPPPPP 304
>gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 69.3 bits (168), Expect = 1e-11
Identities = 50/157 (31%), Positives = 67/157 (42%), Gaps = 12/157 (7%)
Query: 464 IHKAKGLVPEDDTKEKIGPSKPNEIPQQPPPPS---SATNIPSSAPPITSVPRPPTMPPP 520
I A GL+ G + P PPPP SA + S +TS P PP PPP
Sbjct: 297 ISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPP 356
Query: 521 VRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPP 580
P +P PP + +++ PG V+ P PP I AP P+ +PP+ P
Sbjct: 357 PPPATALQAPAVPPPP--APLQIAPG-VLHPAPPPI-AP-----PLVQPSPPVARAAPVC 407
Query: 581 MIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPTS 617
VP +P V +P P P PP+ PP P +
Sbjct: 408 ETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVT 444
Score = 63.9 bits (154), Expect = 5e-10
Identities = 48/146 (32%), Positives = 57/146 (39%), Gaps = 23/146 (15%)
Query: 489 PQQPPPP------SSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPP------ 536
P +PPPP A IP+ T + P T V P P PP
Sbjct: 275 PHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSA 334
Query: 537 ------MASVVRLPPGSVIAPMPPIIHAPRINVVPMPPS----APPIMAPRPPPMIVPTA 586
AS+ PP V P PP A + VP PP+ AP ++ P PPP I P
Sbjct: 335 LSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPP-IAPPL 393
Query: 587 FVPAPPVAPVPAPAPMPPVHPPPPME 612
P+PPVA PVHP P E
Sbjct: 394 VQPSPPVARAAPVCETVPVHPLPQGE 419
Score = 56.6 bits (135), Expect = 8e-08
Identities = 50/161 (31%), Positives = 64/161 (39%), Gaps = 34/161 (21%)
Query: 485 PNEIPQQPPPPSSATNIPSSAPPITSV--------PRPPTMPPPV---------RTTVVS 527
P +P PPPP++A P+ PP + P PP + PP+ V
Sbjct: 349 PPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCE 408
Query: 528 AVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAF 587
VPV P P V LPP P+PP P I PS+P + P P+
Sbjct: 409 TVPVHPLP-QGEVQGLPPPPPPPPLPP----PGIR-----PSSPVTVTALAHP---PSGL 455
Query: 588 VPAPPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P P AP P MP P PP + P S+ K S +P
Sbjct: 456 HPTPSTAPGPHVPLMP---PSPPSQVIPASEP-KRHPSTLP 492
Score = 37.7 bits (86), Expect = 0.038
Identities = 22/63 (34%), Positives = 31/63 (49%), Gaps = 3/63 (4%)
Query: 304 PPPPETPMPPP-LPPTPDQVIVRKDYDPKASKPLP-PAPAPDEYLVSPI-TGEKIPASKM 360
PPPP P+PPP + P+ + + P P P AP P L+ P + IPAS+
Sbjct: 425 PPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEP 484
Query: 361 QEH 363
+ H
Sbjct: 485 KRH 487
Score = 31.6 bits (70), Expect = 2.7
Identities = 19/54 (35%), Positives = 22/54 (40%), Gaps = 10/54 (18%)
Query: 304 PPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPA 357
PPPP PPPLP +R P+PP P P P T + PA
Sbjct: 324 PPPP----PPPLPSALSTSSLRASMTSTPPPPVPPPPPP------PATALQAPA 367
Score = 31.2 bits (69), Expect = 3.6
Identities = 24/95 (25%), Positives = 32/95 (33%), Gaps = 11/95 (11%)
Query: 488 IPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMA-----SVVR 542
+P P P +P PP PP PP +R + V + PP S
Sbjct: 410 VPVHPLPQGEVQGLPPPPPP------PPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAP 463
Query: 543 LPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPR 577
P ++ P PP P P + P I R
Sbjct: 464 GPHVPLMPPSPPSQVIPASEPKRHPSTLPVISDAR 498
Score = 30.8 bits (68), Expect = 4.6
Identities = 18/47 (38%), Positives = 25/47 (53%), Gaps = 2/47 (4%)
Query: 1 MPAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPP 47
+P G VQ +PPPPP P P P +S +A + P G ++P P
Sbjct: 415 LPQGEVQGLPPPPPPPPLP-PPGIRPSSPVTVTALAHPPSG-LHPTP 459
Score = 30.4 bits (67), Expect = 6.1
Identities = 18/63 (28%), Positives = 24/63 (38%), Gaps = 1/63 (1%)
Query: 309 TPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKMQEHMRIGL 368
TP PPP PP P + S P PP P P + + +P + G+
Sbjct: 323 TPPPPP-PPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGV 381
Query: 369 LDP 371
L P
Sbjct: 382 LHP 384
Score = 30.4 bits (67), Expect = 6.1
Identities = 20/62 (32%), Positives = 23/62 (37%), Gaps = 13/62 (20%)
Query: 304 PPPPETPMPPP---------LPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEK 354
PPPP P PPP +PP P + + P P PP AP SP
Sbjct: 348 PPPPVPPPPPPPATALQAPAVPPPPAPLQIA----PGVLHPAPPPIAPPLVQPSPPVARA 403
Query: 355 IP 356
P
Sbjct: 404 AP 405
Score = 30.0 bits (66), Expect = 7.9
Identities = 19/61 (31%), Positives = 29/61 (47%), Gaps = 3/61 (4%)
Query: 11 PPPPVPTEPKQPTE--EEASSKEDSAPSKPVVGIIYP-PPEVRNIVDKTASFVARNGPEF 67
PPPPVP P P + + AP + G+++P PP + + + + VAR P
Sbjct: 348 PPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVC 407
Query: 68 E 68
E
Sbjct: 408 E 408
>gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 69.3 bits (168), Expect = 1e-11
Identities = 50/157 (31%), Positives = 67/157 (42%), Gaps = 12/157 (7%)
Query: 464 IHKAKGLVPEDDTKEKIGPSKPNEIPQQPPPPS---SATNIPSSAPPITSVPRPPTMPPP 520
I A GL+ G + P PPPP SA + S +TS P PP PPP
Sbjct: 297 ISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPP 356
Query: 521 VRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPP 580
P +P PP + +++ PG V+ P PP I AP P+ +PP+ P
Sbjct: 357 PPPATALQAPAVPPPP--APLQIAPG-VLHPAPPPI-AP-----PLVQPSPPVARAAPVC 407
Query: 581 MIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPTS 617
VP +P V +P P P PP+ PP P +
Sbjct: 408 ETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVT 444
Score = 63.9 bits (154), Expect = 5e-10
Identities = 48/146 (32%), Positives = 57/146 (39%), Gaps = 23/146 (15%)
Query: 489 PQQPPPP------SSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPP------ 536
P +PPPP A IP+ T + P T V P P PP
Sbjct: 275 PHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSA 334
Query: 537 ------MASVVRLPPGSVIAPMPPIIHAPRINVVPMPPS----APPIMAPRPPPMIVPTA 586
AS+ PP V P PP A + VP PP+ AP ++ P PPP I P
Sbjct: 335 LSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPP-IAPPL 393
Query: 587 FVPAPPVAPVPAPAPMPPVHPPPPME 612
P+PPVA PVHP P E
Sbjct: 394 VQPSPPVARAAPVCETVPVHPLPQGE 419
Score = 56.6 bits (135), Expect = 8e-08
Identities = 50/161 (31%), Positives = 64/161 (39%), Gaps = 34/161 (21%)
Query: 485 PNEIPQQPPPPSSATNIPSSAPPITSV--------PRPPTMPPPV---------RTTVVS 527
P +P PPPP++A P+ PP + P PP + PP+ V
Sbjct: 349 PPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCE 408
Query: 528 AVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAF 587
VPV P P V LPP P+PP P I PS+P + P P+
Sbjct: 409 TVPVHPLP-QGEVQGLPPPPPPPPLPP----PGIR-----PSSPVTVTALAHP---PSGL 455
Query: 588 VPAPPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P P AP P MP P PP + P S+ K S +P
Sbjct: 456 HPTPSTAPGPHVPLMP---PSPPSQVIPASEP-KRHPSTLP 492
Score = 37.7 bits (86), Expect = 0.038
Identities = 22/63 (34%), Positives = 31/63 (49%), Gaps = 3/63 (4%)
Query: 304 PPPPETPMPPP-LPPTPDQVIVRKDYDPKASKPLP-PAPAPDEYLVSPI-TGEKIPASKM 360
PPPP P+PPP + P+ + + P P P AP P L+ P + IPAS+
Sbjct: 425 PPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEP 484
Query: 361 QEH 363
+ H
Sbjct: 485 KRH 487
Score = 31.6 bits (70), Expect = 2.7
Identities = 19/54 (35%), Positives = 22/54 (40%), Gaps = 10/54 (18%)
Query: 304 PPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPA 357
PPPP PPPLP +R P+PP P P P T + PA
Sbjct: 324 PPPP----PPPLPSALSTSSLRASMTSTPPPPVPPPPPP------PATALQAPA 367
Score = 31.2 bits (69), Expect = 3.6
Identities = 24/95 (25%), Positives = 32/95 (33%), Gaps = 11/95 (11%)
Query: 488 IPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMA-----SVVR 542
+P P P +P PP PP PP +R + V + PP S
Sbjct: 410 VPVHPLPQGEVQGLPPPPPP------PPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAP 463
Query: 543 LPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPR 577
P ++ P PP P P + P I R
Sbjct: 464 GPHVPLMPPSPPSQVIPASEPKRHPSTLPVISDAR 498
Score = 30.8 bits (68), Expect = 4.6
Identities = 18/47 (38%), Positives = 25/47 (53%), Gaps = 2/47 (4%)
Query: 1 MPAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPP 47
+P G VQ +PPPPP P P P +S +A + P G ++P P
Sbjct: 415 LPQGEVQGLPPPPPPPPLP-PPGIRPSSPVTVTALAHPPSG-LHPTP 459
Score = 30.4 bits (67), Expect = 6.1
Identities = 18/63 (28%), Positives = 24/63 (38%), Gaps = 1/63 (1%)
Query: 309 TPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKMQEHMRIGL 368
TP PPP PP P + S P PP P P + + +P + G+
Sbjct: 323 TPPPPP-PPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGV 381
Query: 369 LDP 371
L P
Sbjct: 382 LHP 384
Score = 30.4 bits (67), Expect = 6.1
Identities = 20/62 (32%), Positives = 23/62 (37%), Gaps = 13/62 (20%)
Query: 304 PPPPETPMPPP---------LPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEK 354
PPPP P PPP +PP P + + P P PP AP SP
Sbjct: 348 PPPPVPPPPPPPATALQAPAVPPPPAPLQIA----PGVLHPAPPPIAPPLVQPSPPVARA 403
Query: 355 IP 356
P
Sbjct: 404 AP 405
Score = 30.0 bits (66), Expect = 7.9
Identities = 19/61 (31%), Positives = 29/61 (47%), Gaps = 3/61 (4%)
Query: 11 PPPPVPTEPKQPTE--EEASSKEDSAPSKPVVGIIYP-PPEVRNIVDKTASFVARNGPEF 67
PPPPVP P P + + AP + G+++P PP + + + + VAR P
Sbjct: 348 PPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVC 407
Query: 68 E 68
E
Sbjct: 408 E 408
>gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 69.3 bits (168), Expect = 1e-11
Identities = 50/157 (31%), Positives = 67/157 (42%), Gaps = 12/157 (7%)
Query: 464 IHKAKGLVPEDDTKEKIGPSKPNEIPQQPPPPS---SATNIPSSAPPITSVPRPPTMPPP 520
I A GL+ G + P PPPP SA + S +TS P PP PPP
Sbjct: 297 ISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPP 356
Query: 521 VRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPP 580
P +P PP + +++ PG V+ P PP I AP P+ +PP+ P
Sbjct: 357 PPPATALQAPAVPPPP--APLQIAPG-VLHPAPPPI-AP-----PLVQPSPPVARAAPVC 407
Query: 581 MIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPTS 617
VP +P V +P P P PP+ PP P +
Sbjct: 408 ETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVT 444
Score = 63.9 bits (154), Expect = 5e-10
Identities = 48/146 (32%), Positives = 57/146 (39%), Gaps = 23/146 (15%)
Query: 489 PQQPPPP------SSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPP------ 536
P +PPPP A IP+ T + P T V P P PP
Sbjct: 275 PHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSA 334
Query: 537 ------MASVVRLPPGSVIAPMPPIIHAPRINVVPMPPS----APPIMAPRPPPMIVPTA 586
AS+ PP V P PP A + VP PP+ AP ++ P PPP I P
Sbjct: 335 LSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPP-IAPPL 393
Query: 587 FVPAPPVAPVPAPAPMPPVHPPPPME 612
P+PPVA PVHP P E
Sbjct: 394 VQPSPPVARAAPVCETVPVHPLPQGE 419
Score = 56.6 bits (135), Expect = 8e-08
Identities = 50/161 (31%), Positives = 64/161 (39%), Gaps = 34/161 (21%)
Query: 485 PNEIPQQPPPPSSATNIPSSAPPITSV--------PRPPTMPPPV---------RTTVVS 527
P +P PPPP++A P+ PP + P PP + PP+ V
Sbjct: 349 PPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCE 408
Query: 528 AVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAF 587
VPV P P V LPP P+PP P I PS+P + P P+
Sbjct: 409 TVPVHPLP-QGEVQGLPPPPPPPPLPP----PGIR-----PSSPVTVTALAHP---PSGL 455
Query: 588 VPAPPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P P AP P MP P PP + P S+ K S +P
Sbjct: 456 HPTPSTAPGPHVPLMP---PSPPSQVIPASEP-KRHPSTLP 492
Score = 37.7 bits (86), Expect = 0.038
Identities = 22/63 (34%), Positives = 31/63 (49%), Gaps = 3/63 (4%)
Query: 304 PPPPETPMPPP-LPPTPDQVIVRKDYDPKASKPLP-PAPAPDEYLVSPI-TGEKIPASKM 360
PPPP P+PPP + P+ + + P P P AP P L+ P + IPAS+
Sbjct: 425 PPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEP 484
Query: 361 QEH 363
+ H
Sbjct: 485 KRH 487
Score = 31.6 bits (70), Expect = 2.7
Identities = 19/54 (35%), Positives = 22/54 (40%), Gaps = 10/54 (18%)
Query: 304 PPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPA 357
PPPP PPPLP +R P+PP P P P T + PA
Sbjct: 324 PPPP----PPPLPSALSTSSLRASMTSTPPPPVPPPPPP------PATALQAPA 367
Score = 31.2 bits (69), Expect = 3.6
Identities = 24/95 (25%), Positives = 32/95 (33%), Gaps = 11/95 (11%)
Query: 488 IPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMA-----SVVR 542
+P P P +P PP PP PP +R + V + PP S
Sbjct: 410 VPVHPLPQGEVQGLPPPPPP------PPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAP 463
Query: 543 LPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPR 577
P ++ P PP P P + P I R
Sbjct: 464 GPHVPLMPPSPPSQVIPASEPKRHPSTLPVISDAR 498
Score = 30.8 bits (68), Expect = 4.6
Identities = 18/47 (38%), Positives = 25/47 (53%), Gaps = 2/47 (4%)
Query: 1 MPAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPP 47
+P G VQ +PPPPP P P P +S +A + P G ++P P
Sbjct: 415 LPQGEVQGLPPPPPPPPLP-PPGIRPSSPVTVTALAHPPSG-LHPTP 459
Score = 30.4 bits (67), Expect = 6.1
Identities = 18/63 (28%), Positives = 24/63 (38%), Gaps = 1/63 (1%)
Query: 309 TPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKMQEHMRIGL 368
TP PPP PP P + S P PP P P + + +P + G+
Sbjct: 323 TPPPPP-PPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGV 381
Query: 369 LDP 371
L P
Sbjct: 382 LHP 384
Score = 30.4 bits (67), Expect = 6.1
Identities = 20/62 (32%), Positives = 23/62 (37%), Gaps = 13/62 (20%)
Query: 304 PPPPETPMPPP---------LPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEK 354
PPPP P PPP +PP P + + P P PP AP SP
Sbjct: 348 PPPPVPPPPPPPATALQAPAVPPPPAPLQIA----PGVLHPAPPPIAPPLVQPSPPVARA 403
Query: 355 IP 356
P
Sbjct: 404 AP 405
Score = 30.0 bits (66), Expect = 7.9
Identities = 19/61 (31%), Positives = 29/61 (47%), Gaps = 3/61 (4%)
Query: 11 PPPPVPTEPKQPTE--EEASSKEDSAPSKPVVGIIYP-PPEVRNIVDKTASFVARNGPEF 67
PPPPVP P P + + AP + G+++P PP + + + + VAR P
Sbjct: 348 PPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVC 407
Query: 68 E 68
E
Sbjct: 408 E 408
>gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 69.3 bits (168), Expect = 1e-11
Identities = 50/157 (31%), Positives = 67/157 (42%), Gaps = 12/157 (7%)
Query: 464 IHKAKGLVPEDDTKEKIGPSKPNEIPQQPPPPS---SATNIPSSAPPITSVPRPPTMPPP 520
I A GL+ G + P PPPP SA + S +TS P PP PPP
Sbjct: 297 ISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPP 356
Query: 521 VRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPP 580
P +P PP + +++ PG V+ P PP I AP P+ +PP+ P
Sbjct: 357 PPPATALQAPAVPPPP--APLQIAPG-VLHPAPPPI-AP-----PLVQPSPPVARAAPVC 407
Query: 581 MIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPTS 617
VP +P V +P P P PP+ PP P +
Sbjct: 408 ETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVT 444
Score = 63.9 bits (154), Expect = 5e-10
Identities = 48/146 (32%), Positives = 57/146 (39%), Gaps = 23/146 (15%)
Query: 489 PQQPPPP------SSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPP------ 536
P +PPPP A IP+ T + P T V P P PP
Sbjct: 275 PHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSA 334
Query: 537 ------MASVVRLPPGSVIAPMPPIIHAPRINVVPMPPS----APPIMAPRPPPMIVPTA 586
AS+ PP V P PP A + VP PP+ AP ++ P PPP I P
Sbjct: 335 LSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPP-IAPPL 393
Query: 587 FVPAPPVAPVPAPAPMPPVHPPPPME 612
P+PPVA PVHP P E
Sbjct: 394 VQPSPPVARAAPVCETVPVHPLPQGE 419
Score = 56.6 bits (135), Expect = 8e-08
Identities = 50/161 (31%), Positives = 64/161 (39%), Gaps = 34/161 (21%)
Query: 485 PNEIPQQPPPPSSATNIPSSAPPITSV--------PRPPTMPPPV---------RTTVVS 527
P +P PPPP++A P+ PP + P PP + PP+ V
Sbjct: 349 PPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCE 408
Query: 528 AVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAF 587
VPV P P V LPP P+PP P I PS+P + P P+
Sbjct: 409 TVPVHPLP-QGEVQGLPPPPPPPPLPP----PGIR-----PSSPVTVTALAHP---PSGL 455
Query: 588 VPAPPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P P AP P MP P PP + P S+ K S +P
Sbjct: 456 HPTPSTAPGPHVPLMP---PSPPSQVIPASEP-KRHPSTLP 492
Score = 37.7 bits (86), Expect = 0.038
Identities = 22/63 (34%), Positives = 31/63 (49%), Gaps = 3/63 (4%)
Query: 304 PPPPETPMPPP-LPPTPDQVIVRKDYDPKASKPLP-PAPAPDEYLVSPI-TGEKIPASKM 360
PPPP P+PPP + P+ + + P P P AP P L+ P + IPAS+
Sbjct: 425 PPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEP 484
Query: 361 QEH 363
+ H
Sbjct: 485 KRH 487
Score = 31.6 bits (70), Expect = 2.7
Identities = 19/54 (35%), Positives = 22/54 (40%), Gaps = 10/54 (18%)
Query: 304 PPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPA 357
PPPP PPPLP +R P+PP P P P T + PA
Sbjct: 324 PPPP----PPPLPSALSTSSLRASMTSTPPPPVPPPPPP------PATALQAPA 367
Score = 31.2 bits (69), Expect = 3.6
Identities = 24/95 (25%), Positives = 32/95 (33%), Gaps = 11/95 (11%)
Query: 488 IPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMA-----SVVR 542
+P P P +P PP PP PP +R + V + PP S
Sbjct: 410 VPVHPLPQGEVQGLPPPPPP------PPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAP 463
Query: 543 LPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPR 577
P ++ P PP P P + P I R
Sbjct: 464 GPHVPLMPPSPPSQVIPASEPKRHPSTLPVISDAR 498
Score = 30.8 bits (68), Expect = 4.6
Identities = 18/47 (38%), Positives = 25/47 (53%), Gaps = 2/47 (4%)
Query: 1 MPAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPP 47
+P G VQ +PPPPP P P P +S +A + P G ++P P
Sbjct: 415 LPQGEVQGLPPPPPPPPLP-PPGIRPSSPVTVTALAHPPSG-LHPTP 459
Score = 30.4 bits (67), Expect = 6.1
Identities = 18/63 (28%), Positives = 24/63 (38%), Gaps = 1/63 (1%)
Query: 309 TPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKMQEHMRIGL 368
TP PPP PP P + S P PP P P + + +P + G+
Sbjct: 323 TPPPPP-PPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGV 381
Query: 369 LDP 371
L P
Sbjct: 382 LHP 384
Score = 30.4 bits (67), Expect = 6.1
Identities = 20/62 (32%), Positives = 23/62 (37%), Gaps = 13/62 (20%)
Query: 304 PPPPETPMPPP---------LPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEK 354
PPPP P PPP +PP P + + P P PP AP SP
Sbjct: 348 PPPPVPPPPPPPATALQAPAVPPPPAPLQIA----PGVLHPAPPPIAPPLVQPSPPVARA 403
Query: 355 IP 356
P
Sbjct: 404 AP 405
Score = 30.0 bits (66), Expect = 7.9
Identities = 19/61 (31%), Positives = 29/61 (47%), Gaps = 3/61 (4%)
Query: 11 PPPPVPTEPKQPTE--EEASSKEDSAPSKPVVGIIYP-PPEVRNIVDKTASFVARNGPEF 67
PPPPVP P P + + AP + G+++P PP + + + + VAR P
Sbjct: 348 PPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVC 407
Query: 68 E 68
E
Sbjct: 408 E 408
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 69.3 bits (168), Expect = 1e-11
Identities = 51/156 (32%), Positives = 67/156 (42%), Gaps = 23/156 (14%)
Query: 480 IGPSKPNEIPQQPPPP---SSATNIPSSAPPITSV-----PRPPTMPPPVRTTVVSAVP- 530
+ PS P+ P P PP S T IP P S P PP PPP+ V + P
Sbjct: 563 VPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPP 622
Query: 531 -------VMPRPPMASVVRLPPGSVIAP---MPPIIHAPRINVVPMPPSAP-PIMAPRPP 579
+ P PP++ +PP + +P P +P PP P P PP
Sbjct: 623 SLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPP 682
Query: 580 PMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEP 615
P + +A +P PP P+P A MPP PPPP+ P
Sbjct: 683 PPLPGSAGIPPPP-PPLPGEAGMPP--PPPPLPGGP 715
Score = 62.4 bits (150), Expect = 1e-09
Identities = 59/190 (31%), Positives = 81/190 (42%), Gaps = 30/190 (15%)
Query: 448 QQAAQANITLQEQIEAI--HKAKGLVPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSA 505
QQ A L+ ++ + AK +D K+++ I P PS A P A
Sbjct: 519 QQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPP--A 576
Query: 506 PPI-----TSVPRPPTMPPPVRTTVVSAVPVMPRPP-------MASVVRLPPGSVIAPMP 553
PP+ T +P PP P TT P P PP ++S LP G+ I+P P
Sbjct: 577 PPLPGDSGTIIPPPPA--PGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPP 634
Query: 554 PII---------HAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPP 604
P+ P +P P S P A PPP + +A +P PP P+P A +PP
Sbjct: 635 PLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPP-PPLPGSAGIPP 693
Query: 605 VHPPPPMEDE 614
PPPP+ E
Sbjct: 694 --PPPPLPGE 701
Score = 58.2 bits (139), Expect = 3e-08
Identities = 48/156 (30%), Positives = 63/156 (40%), Gaps = 32/156 (20%)
Query: 485 PNEIPQQPPPP-------SSATNIP-----SSAPPIT---SVPRPPTMPPPVRTTVVSAV 529
P P PPPP SS ++P S PP++ ++P PP +P V S++
Sbjct: 601 PPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSL 660
Query: 530 P----VMPRPPMASVVRLPP------GSVIAPMPPIIHAPRINVVPMPPSAPPIMA---- 575
P + P PP+ R+PP GS P PP P MPP PP+
Sbjct: 661 PGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPP---PPLPGEAGMPPPPPPLPGGPGI 717
Query: 576 PRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPM 611
P PPP P PP +P P P P P+
Sbjct: 718 PPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPV 753
Score = 52.4 bits (124), Expect = 1e-06
Identities = 48/150 (32%), Positives = 58/150 (38%), Gaps = 27/150 (18%)
Query: 492 PPPPSSATNI----PSSAPPITSVPRPPTMP------PPVRTTVVSAVPVMPRPPMASVV 541
PPPP + PSS P T++P PP +P PP SA P PP+
Sbjct: 643 PPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEA 702
Query: 542 RLPP-------GSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVA 594
+PP G I P PP P I PP P + P PPP VPA PV
Sbjct: 703 GMPPPPPPLPGGPGIPPPPPFPGGPGI-----PPPPPGMGMPPPPPF---GFGVPAAPV- 753
Query: 595 PVPAPAPMPPVHPPPPMEDEPTSKKLKTED 624
+P ++ P P KL ED
Sbjct: 754 -LPFGLTPKKLYKPEVQLRRPNWSKLVAED 782
Score = 40.8 bits (94), Expect = 0.004
Identities = 24/71 (33%), Positives = 32/71 (45%), Gaps = 2/71 (2%)
Query: 556 IHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEP 615
+ A I V P PS P+ P PP+ + + PP AP + P PP PPPP P
Sbjct: 556 LSAAAITVPPSVPSRAPV--PPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLP 613
Query: 616 TSKKLKTEDSL 626
+ + SL
Sbjct: 614 GGVCISSPPSL 624
Score = 35.8 bits (81), Expect = 0.14
Identities = 19/50 (38%), Positives = 23/50 (46%), Gaps = 7/50 (14%)
Query: 300 GQKVPPPPETP----MPPPLPPTPDQVIVRKDYDP---KASKPLPPAPAP 342
G +PPPP P +PPP PP P + P +A P PP P P
Sbjct: 663 GTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLP 712
Score = 35.4 bits (80), Expect = 0.19
Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 21/92 (22%)
Query: 538 ASVVRLPPGSVI-APMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPV 596
A+ + +PP AP+PP AP P+P + I+ P P P T P PP P
Sbjct: 558 AAAITVPPSVPSRAPVPP---AP-----PLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPP 609
Query: 597 P---------APAPMP---PVHPPPPMEDEPT 616
P +P +P + PPPP+ + T
Sbjct: 610 PPLPGGVCISSPPSLPGGTAISPPPPLSGDAT 641
Score = 34.7 bits (78), Expect = 0.32
Identities = 17/51 (33%), Positives = 21/51 (41%), Gaps = 1/51 (1%)
Query: 300 GQKVPPPPETPMPPPLPPTPDQVIVRKDYD-PKASKPLPPAPAPDEYLVSP 349
G PPP P PPP PP P V + P + PP P + + P
Sbjct: 594 GDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPP 644
Score = 30.4 bits (67), Expect = 6.1
Identities = 17/47 (36%), Positives = 21/47 (44%), Gaps = 14/47 (29%)
Query: 1 MPAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPP 47
+P GP +PPPPP P P P P P +G+ PPP
Sbjct: 711 LPGGP--GIPPPPPFPGGPGIP------------PPPPGMGMPPPPP 743
Score = 30.0 bits (66), Expect = 7.9
Identities = 13/27 (48%), Positives = 15/27 (55%), Gaps = 5/27 (18%)
Query: 298 EEGQKVPPPPE-----TPMPPPLPPTP 319
+ G +PPPP TP PPP PP P
Sbjct: 582 DSGTIIPPPPAPGDSTTPPPPPPPPPP 608
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 69.3 bits (168), Expect = 1e-11
Identities = 51/156 (32%), Positives = 67/156 (42%), Gaps = 23/156 (14%)
Query: 480 IGPSKPNEIPQQPPPP---SSATNIPSSAPPITSV-----PRPPTMPPPVRTTVVSAVP- 530
+ PS P+ P P PP S T IP P S P PP PPP+ V + P
Sbjct: 572 VPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPP 631
Query: 531 -------VMPRPPMASVVRLPPGSVIAP---MPPIIHAPRINVVPMPPSAP-PIMAPRPP 579
+ P PP++ +PP + +P P +P PP P P PP
Sbjct: 632 SLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPP 691
Query: 580 PMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEP 615
P + +A +P PP P+P A MPP PPPP+ P
Sbjct: 692 PPLPGSAGIPPPP-PPLPGEAGMPP--PPPPLPGGP 724
Score = 62.4 bits (150), Expect = 1e-09
Identities = 59/190 (31%), Positives = 81/190 (42%), Gaps = 30/190 (15%)
Query: 448 QQAAQANITLQEQIEAI--HKAKGLVPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSA 505
QQ A L+ ++ + AK +D K+++ I P PS A P A
Sbjct: 528 QQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPP--A 585
Query: 506 PPI-----TSVPRPPTMPPPVRTTVVSAVPVMPRPP-------MASVVRLPPGSVIAPMP 553
PP+ T +P PP P TT P P PP ++S LP G+ I+P P
Sbjct: 586 PPLPGDSGTIIPPPPA--PGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPP 643
Query: 554 PII---------HAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPP 604
P+ P +P P S P A PPP + +A +P PP P+P A +PP
Sbjct: 644 PLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPP-PPLPGSAGIPP 702
Query: 605 VHPPPPMEDE 614
PPPP+ E
Sbjct: 703 --PPPPLPGE 710
Score = 58.2 bits (139), Expect = 3e-08
Identities = 48/156 (30%), Positives = 63/156 (40%), Gaps = 32/156 (20%)
Query: 485 PNEIPQQPPPP-------SSATNIP-----SSAPPIT---SVPRPPTMPPPVRTTVVSAV 529
P P PPPP SS ++P S PP++ ++P PP +P V S++
Sbjct: 610 PPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSL 669
Query: 530 P----VMPRPPMASVVRLPP------GSVIAPMPPIIHAPRINVVPMPPSAPPIMA---- 575
P + P PP+ R+PP GS P PP P MPP PP+
Sbjct: 670 PGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPP---PPLPGEAGMPPPPPPLPGGPGI 726
Query: 576 PRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPM 611
P PPP P PP +P P P P P+
Sbjct: 727 PPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPV 762
Score = 52.4 bits (124), Expect = 1e-06
Identities = 48/150 (32%), Positives = 58/150 (38%), Gaps = 27/150 (18%)
Query: 492 PPPPSSATNI----PSSAPPITSVPRPPTMP------PPVRTTVVSAVPVMPRPPMASVV 541
PPPP + PSS P T++P PP +P PP SA P PP+
Sbjct: 652 PPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEA 711
Query: 542 RLPP-------GSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVA 594
+PP G I P PP P I PP P + P PPP VPA PV
Sbjct: 712 GMPPPPPPLPGGPGIPPPPPFPGGPGI-----PPPPPGMGMPPPPPF---GFGVPAAPV- 762
Query: 595 PVPAPAPMPPVHPPPPMEDEPTSKKLKTED 624
+P ++ P P KL ED
Sbjct: 763 -LPFGLTPKKLYKPEVQLRRPNWSKLVAED 791
Score = 40.8 bits (94), Expect = 0.004
Identities = 24/71 (33%), Positives = 32/71 (45%), Gaps = 2/71 (2%)
Query: 556 IHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEP 615
+ A I V P PS P+ P PP+ + + PP AP + P PP PPPP P
Sbjct: 565 LSAAAITVPPSVPSRAPV--PPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLP 622
Query: 616 TSKKLKTEDSL 626
+ + SL
Sbjct: 623 GGVCISSPPSL 633
Score = 35.8 bits (81), Expect = 0.14
Identities = 19/50 (38%), Positives = 23/50 (46%), Gaps = 7/50 (14%)
Query: 300 GQKVPPPPETP----MPPPLPPTPDQVIVRKDYDP---KASKPLPPAPAP 342
G +PPPP P +PPP PP P + P +A P PP P P
Sbjct: 672 GTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLP 721
Score = 35.4 bits (80), Expect = 0.19
Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 21/92 (22%)
Query: 538 ASVVRLPPGSVI-APMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPV 596
A+ + +PP AP+PP AP P+P + I+ P P P T P PP P
Sbjct: 567 AAAITVPPSVPSRAPVPP---AP-----PLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPP 618
Query: 597 P---------APAPMP---PVHPPPPMEDEPT 616
P +P +P + PPPP+ + T
Sbjct: 619 PPLPGGVCISSPPSLPGGTAISPPPPLSGDAT 650
Score = 34.7 bits (78), Expect = 0.32
Identities = 17/51 (33%), Positives = 21/51 (41%), Gaps = 1/51 (1%)
Query: 300 GQKVPPPPETPMPPPLPPTPDQVIVRKDYD-PKASKPLPPAPAPDEYLVSP 349
G PPP P PPP PP P V + P + PP P + + P
Sbjct: 603 GDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPP 653
Score = 30.4 bits (67), Expect = 6.1
Identities = 17/47 (36%), Positives = 21/47 (44%), Gaps = 14/47 (29%)
Query: 1 MPAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPP 47
+P GP +PPPPP P P P P P +G+ PPP
Sbjct: 720 LPGGP--GIPPPPPFPGGPGIP------------PPPPGMGMPPPPP 752
Score = 30.0 bits (66), Expect = 7.9
Identities = 13/27 (48%), Positives = 15/27 (55%), Gaps = 5/27 (18%)
Query: 298 EEGQKVPPPPE-----TPMPPPLPPTP 319
+ G +PPPP TP PPP PP P
Sbjct: 591 DSGTIIPPPPAPGDSTTPPPPPPPPPP 617
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 69.3 bits (168), Expect = 1e-11
Identities = 88/387 (22%), Positives = 135/387 (34%), Gaps = 95/387 (24%)
Query: 298 EEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPA 357
EE +PPP E+P+ PP P+ S P +P P+ +SP E++PA
Sbjct: 436 EEMPLLPPPEESPLSPP---------------PEES---PTSPPPEASRLSP-PPEELPA 476
Query: 358 SKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGVEET 417
S + E + + +EE+
Sbjct: 477 SPLPEALHLSR--------------------------------------------PLEES 492
Query: 418 AIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKAKGLVPEDDTK 477
+ E + P E + S + + + L+ + +A L P +
Sbjct: 493 PLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEES 552
Query: 478 EKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRP-PTMPPPVRTTVVSAVPVMP-RP 535
P P E+P PPP +S + P P++ P P PPP + + P P
Sbjct: 553 PLSPP--PEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSP 610
Query: 536 PMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAP 595
P PP PP +P P +PP R P+ V + P P +P
Sbjct: 611 PPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESP 670
Query: 596 VPAPAPMPPVHPP-------PPMEDEPTSKKLK-------TEDSLM------------PE 629
+ P P PP PP ED PTS + EDSLM PE
Sbjct: 671 LSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPE 730
Query: 630 E-EFLRRNKGP-VSIKVQVPNMQDKTE 654
E + R++GP +S + + P++ + E
Sbjct: 731 EPQLCPRSEGPHLSPRPEEPHLSPRPE 757
Score = 66.2 bits (160), Expect = 1e-10
Identities = 90/355 (25%), Positives = 130/355 (36%), Gaps = 54/355 (15%)
Query: 298 EEGQKVPPPPETPMPPP-----LPPTPDQVIVRKDYDPKA---SKPL---PPAPAPDEYL 346
EE PPP E+P PP L P P+++ P+A S+PL P +P P+E
Sbjct: 445 EESPLSPPPEESPTSPPPEASRLSPPPEELPASPL--PEALHLSRPLEESPLSPPPEESP 502
Query: 347 VSPITGEKIPASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAE 406
+SP E P S ++E S E P +E+ L E
Sbjct: 503 LSP-PPESSPFSPLEE--------------------SPLSPPEESPPSPALETPLSPPPE 541
Query: 407 RRTDIFGVEETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHK 466
EE+ + E P E S +++ + + + +
Sbjct: 542 ASPLSPPFEESPLSPPPEELPTSPPPEA------SRLSPPPEESPMSPPPEESPMSPPPE 595
Query: 467 AKGLVPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVV 526
A L P + P P E P PPP +S + P P++ P M PP + +
Sbjct: 596 ASRLFPPFEESPLSPP--PEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRL 653
Query: 527 SAVPVMPR---PPMASVVRLPPGSVIAPMPPIIHAPRINVVP--MPPSAPPIMAPRPPP- 580
S +PV+ R PP S + PP +P P A R++ P P S PP +P PP
Sbjct: 654 SPLPVVSRLSPPPEESPLSPPPEE--SPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPP 711
Query: 581 ----MIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMPEEE 631
M +P P P+ P P P +EP E L P+ E
Sbjct: 712 EDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAE 766
Score = 62.0 bits (149), Expect = 2e-09
Identities = 60/227 (26%), Positives = 88/227 (38%), Gaps = 40/227 (17%)
Query: 452 QANITLQEQIEA-IHKAKGLVPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITS 510
+A + L+ Q+EA +++ L+P + P P E P PPP +S + P P +
Sbjct: 421 KAGVQLEPQLEAPLNEEMPLLPPPEESPLSPP--PEESPTSPPPEASRLSPPPEELPASP 478
Query: 511 VP------RP----PTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPR 560
+P RP P PPP + + P P+ PP +P P + P
Sbjct: 479 LPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEE--SPPSPALETP- 535
Query: 561 INVVPMPPSAPPIMAP------RPPPMIVPTA-------FVPAPPVAPVPAPAPMPPVHP 607
+ PP A P+ P PPP +PT+ P P +P+ P P+ P
Sbjct: 536 ---LSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSP 592
Query: 608 P-------PPMEDEPTSKKLKTEDSLMPEEEFLRRNKGPVSIKVQVP 647
P PP E+ P S E L P E R + P + P
Sbjct: 593 PPEASRLFPPFEESPLSPP-PEESPLSPPPEASRLSPPPEDSPMSPP 638
Score = 58.5 bits (140), Expect = 2e-08
Identities = 96/447 (21%), Positives = 154/447 (34%), Gaps = 92/447 (20%)
Query: 271 QEKAEEPPSQLDQDTQVQDMDEGSDDEEEGQKVPPPPETPMPPP------LPPTPDQVIV 324
+E PP ++ + + + + S EE PPP E+P PP PP D
Sbjct: 640 EESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTS 699
Query: 325 RKDYDPKASKP------------LPPAPAPDEYLVSPIT-GEKIPASKMQEHMRIGLLDP 371
D AS P P P P+E + P + G + + H+ +P
Sbjct: 700 PPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEP 759
Query: 372 RWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGVEETAIGKKIGEEEIQKP 431
Q + Q ++ + E L AE EE + + E +
Sbjct: 760 HLSPQAEEPHLSPQPEEPCLC-AVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPV 818
Query: 432 EEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKAKGLV-------PEDDTKEKIGPSK 484
E+ + Q+ + L + E H + L PE +E
Sbjct: 819 PEEPCLSPQPEESHLSPQSEEP--CLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPA 876
Query: 485 PNEIPQQPPP--PSSATNIPSSA------PPITSVPR------------------PPTMP 518
P E+P PPP PS + + A PP++ +P P +P
Sbjct: 877 PEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLP 936
Query: 519 PPVRTTVVSAVPVM------------------PRPPMASVVRLPPGSVIA--------PM 552
PP+ + +A P P P+A+ + P S P+
Sbjct: 937 PPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPV 996
Query: 553 PPIIHAPRINVVPMPPSAPPIMAPRPPPM-------IVPTAFVPA---PPVAPVPAPAPM 602
PP+I P P+ P++P +M P PP +VP P+ PP P+ P+P+
Sbjct: 997 PPMILPPSPGS-PVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPL 1055
Query: 603 PPVHPPPPMEDEPTSKKLKTEDSLMPE 629
P+ + DE +++TE PE
Sbjct: 1056 SPIGKVVGVSDEAELHEMETEKVSEPE 1082
Score = 53.5 bits (127), Expect = 7e-07
Identities = 86/394 (21%), Positives = 134/394 (34%), Gaps = 60/394 (15%)
Query: 298 EEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPA------PAPDEYLVSPIT 351
EE PPP E+P+ PP +P + P P PA P P+ +SP
Sbjct: 490 EESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSP-P 548
Query: 352 GEKIPASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAERRTDI 411
E+ P S E + P + + + P + S A R
Sbjct: 549 FEESPLSPPPEEL------PTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPP 602
Query: 412 FGVEETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHK---AK 468
F EE+ + E + P E + ++ ++ ++ +
Sbjct: 603 F--EESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVS 660
Query: 469 GLVPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRP-PTMPPP---VRTT 524
L P + P P E P PPP +S + P P + P P PPP + +
Sbjct: 661 RLSPPPEESPLSPP--PEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSL 718
Query: 525 VVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIH-APRINVVPMPPSAP-PIMAPRPP--- 579
+ P++P P + G ++P P H +PR + P A P ++P+P
Sbjct: 719 PLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPC 778
Query: 580 -------PMIVPTAFVP----------------APPVAPVP---APAPMPPVHPPPPMED 613
P + P A P P ++PVP +P P P +
Sbjct: 779 LCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSE 838
Query: 614 EPTSKKLKTEDSLMPEEEFLRRNKGPVSIKVQVP 647
EP E L PE E K P+S + + P
Sbjct: 839 EPCLSPRPEESHLSPELE-----KPPLSPRPEKP 867
Score = 52.0 bits (123), Expect = 2e-06
Identities = 82/389 (21%), Positives = 134/389 (34%), Gaps = 56/389 (14%)
Query: 271 QEKAEEPPSQLDQDTQVQDMDEGSDDEEEGQKVPPPPETPMPPP--------------LP 316
+E PP + + + S E+ PPP E+PM PP L
Sbjct: 604 EESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLS 663
Query: 317 PTPDQVIVRKDYD-------PKASKPLPP------APAPDEYLVSPITGEKIPASKMQEH 363
P P++ + + P+AS+ PP +P P++ SP + + + ++E
Sbjct: 664 PPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEES 723
Query: 364 MRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGVEETAIGKKI 423
+ L + L R +E + E L AE EE +
Sbjct: 724 PLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVP 783
Query: 424 GEEEIQKPEEKVTWDGHSGSMARTQQAAQANIT-------LQEQIEAIHKAKGLVPEDDT 476
E + E + + Q + +++ L Q E H L P+ +
Sbjct: 784 EEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESH----LSPQ--S 837
Query: 477 KEKIGPSKPNEIPQQP----PPPSSATNIPSSAPPITSVPRP-PTMPPPVRTTV--VSAV 529
+E +P E P PP S P P P P PPP ++ +
Sbjct: 838 EEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGE 897
Query: 530 PVMPRPPMASVVRLPPGSVIAPM-PPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFV 588
P + P + LP ++P P + + P+PP PI+ PP + P +
Sbjct: 898 PALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGEL 957
Query: 589 PAP--------PVAPVPAPAPMPPVHPPP 609
P P +P+ AP P+ PPP
Sbjct: 958 EYPFGAKGDSDPESPLAAPILETPISPPP 986
Score = 49.3 bits (116), Expect = 1e-05
Identities = 88/423 (20%), Positives = 139/423 (32%), Gaps = 61/423 (14%)
Query: 224 PNEQGNFPPPTT------PEELGARILIQERYEKFGESEEVEMEVESDEEDDKQEKAEEP 277
P E PPP PEEL A L E + + +E E P
Sbjct: 453 PEESPTSPPPEASRLSPPPEELPASPL----------PEALHLSRPLEESPLSPPPEESP 502
Query: 278 PSQLDQDTQVQDMDEGSDDEEEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLP 337
S + + ++E E P ETP+ PP +P P PL
Sbjct: 503 LSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLS-------PPFEESPLS 555
Query: 338 PAPAPDEYLVSPITGEKIPASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDI 397
P P E++P S E R+ ++ +P +
Sbjct: 556 PPP------------EELPTSPPPEASRL----------------SPPPEESPMSPPPE- 586
Query: 398 ESSLKQLAERRTDIFGVEETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITL 457
ES + E EE+ + E + P E + ++ ++
Sbjct: 587 ESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSP 646
Query: 458 QEQIEAIHKAKGLVPEDDTKEKIGPSKP-NEIPQQPPPPSSATNIPSSAPPITSVPR-PP 515
++ + + E+ S P E P PPP +S + P P + P P
Sbjct: 647 PPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSP 706
Query: 516 TMPPP---VRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIH-APRINVVPMPPSA- 570
PPP + + + P++P P + G ++P P H +PR + P A
Sbjct: 707 ASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAE 766
Query: 571 PPIMAPRP-PPMIVPTAFVP-APPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 628
P ++P+P P + P P A P +P P P +EP + E L P
Sbjct: 767 EPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSP 826
Query: 629 EEE 631
+ E
Sbjct: 827 QPE 829
Score = 43.1 bits (100), Expect = 0.001
Identities = 76/362 (20%), Positives = 125/362 (34%), Gaps = 52/362 (14%)
Query: 271 QEKAEEPPSQLDQDTQVQDMDEGSDDEEEGQKVPPPPETPMPPP------LPPTPDQVIV 324
+E PP + + + S EE PPP E+PM PP PP + +
Sbjct: 550 EESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPL- 608
Query: 325 RKDYDPKASKPLPP-------APAPDEYLVSPITGEKIPASKMQEHMRIGLLDPRWLEQR 377
P PL P +P P++ +SP E S M + L P + R
Sbjct: 609 ---SPPPEESPLSPPPEASRLSPPPEDSPMSPPPEE----SPMSPPPEVSRLSPLPVVSR 661
Query: 378 DRSIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGVEETAIGKKIGEEEIQKPEEKVTW 437
+ + + P + +S A R + T+ PE+
Sbjct: 662 ---LSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTS----------PPPEDSPAS 708
Query: 438 DGHSGSMARTQQAAQANITLQEQIEAIHKAKG--LVPE-DDTKEKIGPSKPNEIPQQPPP 494
S+ + L E+ + +++G L P ++ P +P+ PQ P
Sbjct: 709 PPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEP 768
Query: 495 PSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVP----VMPRPPMASVVRLPPGSVIA 550
S P + +VP P + P +S P + P+ + +P ++
Sbjct: 769 HLSP---QPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLS 825
Query: 551 PMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPP 610
P P H P S P ++PRP + + + PP++P P P P P P
Sbjct: 826 PQPEESHL-------SPQSEEPCLSPRPEESHL-SPELEKPPLSPRPEKPPEEPGQCPAP 877
Query: 611 ME 612
E
Sbjct: 878 EE 879
Score = 43.1 bits (100), Expect = 0.001
Identities = 39/124 (31%), Positives = 48/124 (38%), Gaps = 20/124 (16%)
Query: 489 PQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRP---PMASVVRLPP 545
PQ+PPP + P S P I RP + P + P+ PRP P S LPP
Sbjct: 2349 PQEPPPAQALAPSPPSHPDIF---RPGSYTDPY-----AQPPLTPRPQPPPPESCCALPP 2400
Query: 546 GSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAP--PVAPVPAPAPMP 603
S+ P P P P S +P P + AF P+P P P P P
Sbjct: 2401 RSL--PSDPFSRVPA-----SPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRP 2453
Query: 604 PVHP 607
P P
Sbjct: 2454 PSRP 2457
Score = 40.8 bits (94), Expect = 0.004
Identities = 32/103 (31%), Positives = 45/103 (43%), Gaps = 17/103 (16%)
Query: 550 APMPPIIHAPRINVVPMPP---SAPPIMAPRPPPMIV----------PTAFVPAPPVAPV 596
AP PP H+ NV + SAPP P PPP + P +P P+A
Sbjct: 4885 APEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEP 4944
Query: 597 PAPAPMPPVHPPPPMEDEPTSKKLKT-EDSLMPEEEFLRRNKG 638
P P+P+P P +P ++ + EDS P L++ KG
Sbjct: 4945 PVPSPLPLASSPESARPKPRARPPEEGEDSRPPR---LKKWKG 4984
Score = 40.4 bits (93), Expect = 0.006
Identities = 32/100 (32%), Positives = 42/100 (42%), Gaps = 17/100 (17%)
Query: 270 KQEK-AEEPPSQLDQDTQVQDMDEGSDDEEEGQKVPPPPETPMPPPLP------PTPDQV 322
KQE A EPP+Q V ++D Q PPPE P PPP P P +
Sbjct: 4880 KQESPAPEPPTQHSYTYNVSNLDVR-------QLSAPPPEEPSPPPSPLAPSPASPPTEP 4932
Query: 323 IVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKMQE 362
+V +P A PP P+P SP + P ++ E
Sbjct: 4933 LVELPTEPLAE---PPVPSPLPLASSPESARPKPRARPPE 4969
Score = 39.3 bits (90), Expect = 0.013
Identities = 87/428 (20%), Positives = 140/428 (32%), Gaps = 75/428 (17%)
Query: 254 ESEEVEMEVESDEEDDKQEKAEEP-------PSQLDQDTQVQDMDEGSDDEEEGQKVPPP 306
+ EE+ + ++ EE EEP S L ++ + ++ ++ P
Sbjct: 800 QPEELHLSPQT-EEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKP 858
Query: 307 PETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKI-------PASK 359
P +P P P P Q A + LP P P E +SP+ GE P S
Sbjct: 859 PLSPRPEKPPEEPGQC--------PAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSP 910
Query: 360 MQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGVEETAI 419
+ E + + + S+ + + P L + A G E
Sbjct: 911 LPEELPLS-------PSGEPSLSPQLMPPDPLPPPLS--PIITAAAPPALSPLGELEYPF 961
Query: 420 GKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKAKGLVPEDDTKEK 479
G K G+ + + P + +AN T E + ++
Sbjct: 962 GAK-GDSDPESPLAAPILE------TPISPPPEANCTDPEPVPP------MILPPSPGSP 1008
Query: 480 IGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPR---PPTMPPPVRTTVVSAVPVMPRPP 536
+GP+ P I +P PP + + S P S P PP +P V + + V+
Sbjct: 1009 VGPASP--ILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSD 1066
Query: 537 MASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMI----------VPTA 586
A + + V P P + + +P P AP P P + P
Sbjct: 1067 EAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLD 1126
Query: 587 FVPAPPVAPVPAPAP-------------MPP--VHPPPPMEDEPTSKKLKTEDSLMPEEE 631
+ AP P P P + P + P PME P K+ + S E+E
Sbjct: 1127 GIDAPGSQPEPGQTPGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQE 1186
Query: 632 FLRRNKGP 639
R P
Sbjct: 1187 EPRAPVAP 1194
Score = 38.9 bits (89), Expect = 0.017
Identities = 39/176 (22%), Positives = 66/176 (37%), Gaps = 29/176 (16%)
Query: 442 GSMARTQQAAQANITLQEQIEAIHKAKGLVPEDDTKEKIGPSKPNEIPQQPPPPSSATNI 501
G +A+ Q + Q+Q++A+ + L + + + P + P P +
Sbjct: 4203 GVLAKNPQLRHLSPQQQQQLQALLMQRQL----QQSQAVRQTPPYQEPGTQTSPLQG--L 4256
Query: 502 PSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSV-IAPMPPIIHAPR 560
P + P P T P + + PRP + PPG++ P+ +H
Sbjct: 4257 LGCQPQLGGFPGPQTGP-------LQELGAGPRPQGPPRLPAPPGALSTGPVLGPVH--- 4306
Query: 561 INVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPT 616
P PP + P RP + P++ +P A +PP HP P PT
Sbjct: 4307 ----PTPPPSSPQEPKRPSQLPSPSS--------QLPTEAQLPPTHPGTPKPQGPT 4350
Score = 37.4 bits (85), Expect = 0.050
Identities = 50/177 (28%), Positives = 70/177 (39%), Gaps = 20/177 (11%)
Query: 445 ARTQQAAQANITLQEQIEAIHKAKGLVPEDDTKEKIGPSKPNEIPQQP-----PPPSSAT 499
A+ +AA +Q+Q E+ + V D ++ P+ IP QP PPP++A
Sbjct: 2064 AKDNRAAHRINKVQKQAESQINKQTKVG-DIARKTDRPALHLRIPPQPGALGSPPPAAAP 2122
Query: 500 NI---PSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMP--- 553
I + P S + PP +VP P P ++LPP V A +P
Sbjct: 2123 TIFIGSPTTPAGLSTSADGFLKPPA-----GSVPG-PDSPGELFLKLPP-QVPAQVPSQD 2175
Query: 554 PIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPP 610
P AP + P P+APP P P P P A P + P H PP
Sbjct: 2176 PFGLAPAYPLEPRFPTAPPTYPPYPSPTGAP-AQPPMLGASSRPGAGQPGEFHTTPP 2231
Score = 36.6 bits (83), Expect = 0.085
Identities = 27/90 (30%), Positives = 33/90 (36%), Gaps = 3/90 (3%)
Query: 491 QPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIA 550
QPPPP S +P + P R P P ++ S P+ PRP A P +
Sbjct: 2388 QPPPPESCCALPPRSLPSDPFSRVPASP---QSQSSSQSPLTPRPLSAEAFCPSPVTPRF 2444
Query: 551 PMPPIIHAPRINVVPMPPSAPPIMAPRPPP 580
P P P AP PRP P
Sbjct: 2445 QSPDPYSRPPSRPQSRDPFAPLHKPPRPQP 2474
Score = 35.4 bits (80), Expect = 0.19
Identities = 35/134 (26%), Positives = 46/134 (34%), Gaps = 30/134 (22%)
Query: 477 KEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPP 536
KE++G S P+ PP + PSS + + ++T V P+ PR
Sbjct: 2289 KEELGASSPS----YGPPNLGFVDSPSSGTHLGGLE--------LKTPDVFKAPLTPRA- 2335
Query: 537 MASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPV 596
+ V PG + P P PP A P P P F P P
Sbjct: 2336 -SQVEPQSPGLGLRPQEP----------------PPAQALAPSPPSHPDIFRPGSYTDPY 2378
Query: 597 PAPAPMPPVHPPPP 610
P P PPPP
Sbjct: 2379 AQPPLTPRPQPPPP 2392
Score = 34.7 bits (78), Expect = 0.32
Identities = 35/113 (30%), Positives = 46/113 (40%), Gaps = 11/113 (9%)
Query: 525 VVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAP-RPPPMIV 583
V S P P P P G + P + AP +P+ P PP +P PPP
Sbjct: 401 VTSMQPKEPGPLQCEAK--PLGKAGVQLEPQLEAPLNEEMPLLP--PPEESPLSPPPEES 456
Query: 584 PTAFVP-APPVAPVPAPAPMPP----VHPPPPMEDEPTSKKLKTEDSLMPEEE 631
PT+ P A ++P P P P +H P+E+ P S E L P E
Sbjct: 457 PTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPP-PEESPLSPPPE 508
Score = 33.9 bits (76), Expect = 0.55
Identities = 33/137 (24%), Positives = 43/137 (31%), Gaps = 1/137 (0%)
Query: 470 LVPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAV 529
L P + E PS Q P P S + P S P + +PP PP ++
Sbjct: 2425 LTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSL 2484
Query: 530 PVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVP 589
LP G + N V P + + P P P A
Sbjct: 2485 AHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGE 2544
Query: 590 APPVAPVPAPAPMPPVH 606
PVP P +PP H
Sbjct: 2545 PSLKPPVPQPG-LPPPH 2560
Score = 33.9 bits (76), Expect = 0.55
Identities = 55/245 (22%), Positives = 89/245 (36%), Gaps = 56/245 (22%)
Query: 439 GHSGSMARTQQAAQANITLQEQIEAIHKAKGLVPEDDTKEKIGPSKP-------NEIPQQ 491
G GS + ++ ++ ++ Q + G P T+ +GP +P N Q
Sbjct: 4117 GQLGSGSSSEASSVPHLLAQPSVSL-----GDQPGSMTQNLLGPQQPMLERPMQNNTGPQ 4171
Query: 492 PPPPSSATNIPSSAPPITSVP--------------RPPTMP--PPVRTTVVSAVPVMPRP 535
PP P P + +P + P + P + + A+ + +
Sbjct: 4172 PPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQL 4231
Query: 536 PMASVVRLPP-----GSVIAPMPPIIHA-PRINVVPMPPSAPPI---MAPRP--PPMIVP 584
+ VR P G+ +P+ ++ P++ P P + P PRP PP +
Sbjct: 4232 QQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRL-- 4289
Query: 585 TAFVPAPPVAPVPAPA--PMPPVHPPPPMEDEP--------TSKKLKTEDSLMPEEEFLR 634
PAPP A P P+ P PPP EP S +L TE L P
Sbjct: 4290 ----PAPPGALSTGPVLGPVHPT-PPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTP 4344
Query: 635 RNKGP 639
+ +GP
Sbjct: 4345 KPQGP 4349
Score = 33.1 bits (74), Expect = 0.94
Identities = 36/114 (31%), Positives = 42/114 (36%), Gaps = 20/114 (17%)
Query: 512 PRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAP 571
P PPT V + PP PP S +AP P PP+ P
Sbjct: 4886 PEPPTQHSYTYNVSNLDVRQLSAPPPEEPS--PPPSPLAPSP-----------ASPPTEP 4932
Query: 572 PIMAPRPPPMIVPTAFVPAP-PVAPVPAPA-PMPPVHPPPPMEDE--PTSKKLK 621
+ P P P VP+P P+A P A P P PP ED P KK K
Sbjct: 4933 LVELPTEPLAEPP---VPSPLPLASSPESARPKPRARPPEEGEDSRPPRLKKWK 4983
Score = 30.4 bits (67), Expect = 6.1
Identities = 17/45 (37%), Positives = 22/45 (48%), Gaps = 1/45 (2%)
Query: 5 PVQAVPPPPPVPTEPKQPTEEE-ASSKEDSAPSKPVVGIIYPPPE 48
P + P PP + P P EE S E+S PS + + PPPE
Sbjct: 497 PPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPE 541
Score = 30.4 bits (67), Expect = 6.1
Identities = 28/109 (25%), Positives = 45/109 (41%), Gaps = 16/109 (14%)
Query: 268 DDKQEKAEEPPSQLDQDTQVQDMDEGSDDEEEGQKVPPPPE--------TPMPPPLPPTP 319
D E+ E P SQ D D+ + EG+ P PE P P P TP
Sbjct: 1809 DGGSERKELPTSQKGDDGP--DIADEESRGLEGKADTPGPEDGGVKASPVPSDPEKPGTP 1866
Query: 320 DQVIVRKDYDPKASKPLPPAPAPD-EYLVSPITGEKIPASKMQEHMRIG 367
+ ++ D D +++ LP + D + L + G S+ ++H+ G
Sbjct: 1867 GEGMLSSDLDRISTEELPKMESKDLQQLFKDVLG-----SEREQHLGCG 1910
Score = 30.4 bits (67), Expect = 6.1
Identities = 21/53 (39%), Positives = 26/53 (49%), Gaps = 6/53 (11%)
Query: 482 PSKPNEI--PQQPPPPSSATNIPSSAPPI---TSVPRPPTM-PPPVRTTVVSA 528
PS P E P Q P PSS + PP T P+ PT+ PPP R + +A
Sbjct: 4311 PSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAA 4363
Score = 30.0 bits (66), Expect = 7.9
Identities = 15/38 (39%), Positives = 16/38 (42%)
Query: 305 PPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAP 342
PPP + P P PD DP A PL P P P
Sbjct: 2352 PPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQP 2389
>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
Length = 464
Score = 68.9 bits (167), Expect = 2e-11
Identities = 53/153 (34%), Positives = 61/153 (39%), Gaps = 27/153 (17%)
Query: 469 GLVPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSA 528
GL P E + P P +P P PP + P + P PP +PPP A
Sbjct: 240 GLPPRPPLPESLPPPPPGGLPLPPMPP--------TGPAPSGPPGPPQLPPP-------A 284
Query: 529 VPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSA-PPIMAPRPPPMIVPTAF 587
V P P+ PP S + P P +H P V P P PP PP P
Sbjct: 285 PGVHPPAPVVH----PPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVHPP---APGVH 337
Query: 588 VPAPPVAPVPAPA---PMPPVHPPPPMEDEPTS 617
PAP V P PAP P P VHPP P P S
Sbjct: 338 PPAPGVHP-PAPGVHPPAPGVHPPAPGVHPPPS 369
Score = 61.6 bits (148), Expect = 2e-09
Identities = 51/148 (34%), Positives = 63/148 (42%), Gaps = 26/148 (17%)
Query: 484 KPNEIPQQPPPPSSATNIPSSAPPITS--VPRPP---TMPPPVRTTVVSAVPVMPRPPMA 538
K + P P P+ + PP+ + PRPP ++PPP +P+ P PP
Sbjct: 213 KMEKPPAPPSLPAGPPGVKRPPPPLMNGLPPRPPLPESLPPPPP----GGLPLPPMPPTG 268
Query: 539 SVVRLPPGSVIAPMP--------PIIHAPRINVVPMPPSA-PPIMAPRPPPMIV--PTAF 587
PPG P P P++H P V P P PP PP V PT+
Sbjct: 269 PAPSGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSG 328
Query: 588 V--PAPPVAPVPAPA---PMPPVHPPPP 610
V PAP V P PAP P P VHPP P
Sbjct: 329 VHPPAPGVHP-PAPGVHPPAPGVHPPAP 355
Score = 50.4 bits (119), Expect = 6e-06
Identities = 38/126 (30%), Positives = 45/126 (35%), Gaps = 16/126 (12%)
Query: 492 PPPPSSATNIPSSAPPITSVPRPPT-----MPPPVRTTVVSAVPVMP--RPPMASVVRLP 544
PP P P PP V PP+ P V + P P PP +
Sbjct: 345 PPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQA 404
Query: 545 PGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPP 604
PG + P PP +H V P PP P PP P PP+ P P+ P
Sbjct: 405 PG--VHPQPPGVHPSAPGVHPQPPGVHPSNPGVHPP-------TPMPPMLRPPLPSEGPG 455
Query: 605 VHPPPP 610
PPPP
Sbjct: 456 NIPPPP 461
Score = 50.1 bits (118), Expect = 7e-06
Identities = 34/96 (35%), Positives = 43/96 (44%), Gaps = 20/96 (20%)
Query: 532 MPRPPMASVVRLPPGSVIAPMPPIIHA--PRINVVPMPPSAPPIMAPRPPPMIVPTAFVP 589
M +PP + P V P PP+++ PR P+P S PP PPP +P P
Sbjct: 214 MEKPPAPPSLPAGPPGVKRPPPPLMNGLPPR---PPLPESLPP-----PPPGGLPLP--P 263
Query: 590 APPVAPVPA--------PAPMPPVHPPPPMEDEPTS 617
PP P P+ P P P VHPP P+ P S
Sbjct: 264 MPPTGPAPSGPPGPPQLPPPAPGVHPPAPVVHPPAS 299
Score = 48.5 bits (114), Expect = 2e-05
Identities = 49/153 (32%), Positives = 61/153 (39%), Gaps = 23/153 (15%)
Query: 480 IGPSKPNEIPQQPP--PPSSATNIPSSA--PPITSV-PRPPTMPPPVRTTVVSAVPVMPR 534
+ P P P P PP+S + P+ PP V P P + PP A V P
Sbjct: 308 VHPPAPGVHPPAPGVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHP- 366
Query: 535 PPMASVVRLPPG-----SVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTA--F 587
PP A V PG + P P +H P + P P P PP + P+A
Sbjct: 367 PPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHP-----QPPGVHPSAPGV 421
Query: 588 VPAPP-VAP----VPAPAPMPPVHPPPPMEDEP 615
P PP V P V P PMPP+ PP + P
Sbjct: 422 HPQPPGVHPSNPGVHPPTPMPPMLRPPLPSEGP 454
Score = 37.0 bits (84), Expect = 0.065
Identities = 54/246 (21%), Positives = 78/246 (31%), Gaps = 21/246 (8%)
Query: 300 GQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASK 359
G K PPPP PP PP P+ + P PLPP P P ++P
Sbjct: 229 GVKRPPPPLMNGLPPRPPLPESL----PPPPPGGLPLPPMPPTGPAPSGPPGPPQLPPPA 284
Query: 360 MQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAERRTDIF----GVE 415
H ++ P + V+ P + + + GV
Sbjct: 285 PGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVHPPAPGVHPPAPGVH 344
Query: 416 ETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIH-KAKGLVPED 474
A G + P V +G + A + Q +H A G+ P+
Sbjct: 345 PPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQ- 403
Query: 475 DTKEKIGPSKPNEIPQ----QPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVP 530
+ P P P P PP + P PP P PP + PP+ + +P
Sbjct: 404 --APGVHPQPPGVHPSAPGVHPQPPGVHPSNPGVHPP---TPMPPMLRPPLPSEGPGNIP 458
Query: 531 VMPRPP 536
P PP
Sbjct: 459 --PPPP 462
>gi|7706501 WW domain binding protein 11 [Homo sapiens]
Length = 641
Score = 68.9 bits (167), Expect = 2e-11
Identities = 91/355 (25%), Positives = 125/355 (35%), Gaps = 72/355 (20%)
Query: 302 KVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKMQ 361
++PP + P PPP PP P QV+ + LPP ++ L SP ++ +
Sbjct: 192 RLPPGRKPPGPPPGPPPP-QVVQMYGRKVGFALDLPPRRRDEDMLYSPELAQRGHDDDVS 250
Query: 362 EHMRIGLLDPRWLEQRDRSIREKQSDD--------------------------EVYAPGL 395
D + E D+ + +DD E GL
Sbjct: 251 STSE----DDGYPEDMDQDKHDDSTDDSDTDKSDGESDGDEFVHRDNGERDNNEEKKSGL 306
Query: 396 DIESS--------LKQLAERRTDIFGVEETAIGKKIGEE--EIQKPEEKVTWDGHSGSMA 445
+ + K+ + T + + G++I EE E+++ E D S A
Sbjct: 307 SVRFADMPGKSRKKKKNMKELTPLQAMMLRMAGQEIPEEGREVEEFSEDDDEDDSDDSEA 366
Query: 446 RTQQAAQANITLQEQIEAIHKAKGLVPEDDTKEKIGPSKPNEIP----QQPPPPSSATNI 501
Q Q HK + T + P +P Q PP P
Sbjct: 367 EKQSQKQ------------HKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLG 414
Query: 502 PSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRI 561
P APP+ P PPT PP P RPP +R P ++ P PP P
Sbjct: 415 PPPAPPLRP-PGPPTGLPPGPPP---GAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGP 470
Query: 562 NVVPMPPSAPPIMAPR-PPPMIVPTAFVPAPPVAPVPAPAPM-----PPVHPPPP 610
P PP PP PR PPP + P PAPP P P P M PP+ P PP
Sbjct: 471 PPGP-PPGLPPGPPPRGPPPRLPP----PAPPGIPPPRPGMMRPPLVPPLGPAPP 520
Score = 46.2 bits (108), Expect = 1e-04
Identities = 36/117 (30%), Positives = 45/117 (38%), Gaps = 16/117 (13%)
Query: 482 PSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVV 541
P +P P PPP P PP P PP +PPP P M RPP+
Sbjct: 464 PGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPR--------PGMMRPPL---- 511
Query: 542 RLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPA 598
+PP + P PP + P P SAPP + RP A + A + A
Sbjct: 512 -VPP---LGPAPPGLFPPAPLPNPGVLSAPPNLIQRPKADDTSAATIEKKATATISA 564
Score = 42.7 bits (99), Expect = 0.001
Identities = 39/156 (25%), Positives = 58/156 (37%), Gaps = 15/156 (9%)
Query: 191 ERKKEEEEKEKERVAYAQIDWHDFVVVETVDFQPNEQGNFPPPTTPEELGARILIQERYE 250
ER EE+K V +A + ++ N T + + R+ QE E
Sbjct: 295 ERDNNEEKKSGLSVRFADMPGKS----------RKKKKNMKELTPLQAMMLRMAGQEIPE 344
Query: 251 KFGESEEVEMEVESDEEDDKQEKAEEPPSQLDQDTQVQDMDEGSDDEEEGQKVPP----P 306
+ E EE + + D+ DD + + + ++ S + Q VPP
Sbjct: 345 EGREVEEFSEDDDEDDSDDSEAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQA 404
Query: 307 PETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAP 342
P P PPPL P P + R P P PP AP
Sbjct: 405 PPMPGPPPLGPPPAPPL-RPPGPPTGLPPGPPPGAP 439
Score = 40.0 bits (92), Expect = 0.008
Identities = 30/103 (29%), Positives = 40/103 (38%), Gaps = 9/103 (8%)
Query: 254 ESEEVEMEVESDEEDDKQEKAEEPPSQLDQDTQVQDMDEGSDDEEEGQKVPP---PPET- 309
E EVE E D+EDD + E SQ + + + +G+ Q+ PP PP
Sbjct: 345 EGREVEEFSEDDDEDDSDDSEAEKQSQ--KQHKEESHSDGTSTASSQQQAPPQSVPPSQI 402
Query: 310 ---PMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSP 349
PMP P P P + P P P P +L P
Sbjct: 403 QAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPP 445
Score = 34.7 bits (78), Expect = 0.32
Identities = 23/80 (28%), Positives = 34/80 (42%), Gaps = 10/80 (12%)
Query: 551 PMPPIIHAPR---INVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPV-------APVPAPA 600
P+P + HAP I +P+P + PP + + PT V P+ P
Sbjct: 140 PLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKP 199
Query: 601 PMPPVHPPPPMEDEPTSKKL 620
P PP PPPP + +K+
Sbjct: 200 PGPPPGPPPPQVVQMYGRKV 219
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.132 0.390
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,843,997
Number of Sequences: 37866
Number of extensions: 2818270
Number of successful extensions: 69793
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 783
Number of HSP's successfully gapped in prelim test: 1673
Number of HSP's that attempted gapping in prelim test: 22435
Number of HSP's gapped (non-prelim): 27076
length of query: 728
length of database: 18,247,518
effective HSP length: 110
effective length of query: 618
effective length of database: 14,082,258
effective search space: 8702835444
effective search space used: 8702835444
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.