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Search of human proteins with 52487277
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|52487277 SP140 nuclear body protein isoform 2 [Homo sapiens]
(172 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|52487277 SP140 nuclear body protein isoform 2 [Homo sapiens] 350 4e-97
gi|217330601 SP140 nuclear body protein isoform 1 [Homo sapiens] 275 2e-74
gi|134133279 SP140 nuclear body protein-like [Homo sapiens] 117 4e-27
gi|122939208 nuclear antigen Sp100 isoform 1 [Homo sapiens] 117 6e-27
gi|19923236 nuclear antigen Sp100 isoform 2 [Homo sapiens] 117 6e-27
gi|190343010 SP110 nuclear body protein isoform a [Homo sapiens] 97 9e-21
gi|190343008 SP110 nuclear body protein isoform b [Homo sapiens] 97 9e-21
gi|190343006 SP110 nuclear body protein isoform c [Homo sapiens] 97 9e-21
gi|4557291 autoimmune regulator isoform 1 [Homo sapiens] 30 1.0
gi|194097432 hypothetical protein LOC285966 B [Homo sapiens] 29 1.8
gi|194097428 hypothetical protein LOC285966 A [Homo sapiens] 29 1.8
gi|194097425 hypothetical protein LOC285966 A [Homo sapiens] 29 1.8
gi|148746183 ubiquitin specific protease 35 [Homo sapiens] 29 2.3
gi|21264623 suppression of tumorigenicity 7-like isoform 4 [Homo... 28 3.0
gi|21264621 suppression of tumorigenicity 7-like isoform 3 [Homo... 28 3.0
gi|21264619 suppression of tumorigenicity 7-like isoform 2 [Homo... 28 3.0
gi|20270257 suppression of tumorigenicity 7-like isoform 1 [Homo... 28 3.0
gi|110832839 ATP-binding cassette, sub-family C, member 9 isofor... 27 6.7
gi|110832835 ATP-binding cassette, sub-family C, member 9 isofor... 27 6.7
gi|110832837 ATP-binding cassette, sub-family C, member 9 isofor... 27 6.7
>gi|52487277 SP140 nuclear body protein isoform 2 [Homo sapiens]
Length = 172
Score = 350 bits (897), Expect = 4e-97
Identities = 172/172 (100%), Positives = 172/172 (100%)
Query: 1 MAQQGQQGQMASGDSNLNFRMVAEIQNVEGQNLQEQVCPEPIFRFFRENKVEIASAITRP 60
MAQQGQQGQMASGDSNLNFRMVAEIQNVEGQNLQEQVCPEPIFRFFRENKVEIASAITRP
Sbjct: 1 MAQQGQQGQMASGDSNLNFRMVAEIQNVEGQNLQEQVCPEPIFRFFRENKVEIASAITRP 60
Query: 61 FPFLMGLRDRSFISEQMYEHFQEAFRNLVPVTRVMYCVLSELEKTFGWSHLEALFSRINL 120
FPFLMGLRDRSFISEQMYEHFQEAFRNLVPVTRVMYCVLSELEKTFGWSHLEALFSRINL
Sbjct: 61 FPFLMGLRDRSFISEQMYEHFQEAFRNLVPVTRVMYCVLSELEKTFGWSHLEALFSRINL 120
Query: 121 MAYPDLNEIYRSFQNENLSSSAVLCQLVSPNKDWRSHEESLAHTGTLRRSCM 172
MAYPDLNEIYRSFQNENLSSSAVLCQLVSPNKDWRSHEESLAHTGTLRRSCM
Sbjct: 121 MAYPDLNEIYRSFQNENLSSSAVLCQLVSPNKDWRSHEESLAHTGTLRRSCM 172
>gi|217330601 SP140 nuclear body protein isoform 1 [Homo sapiens]
Length = 867
Score = 275 bits (702), Expect = 2e-74
Identities = 135/135 (100%), Positives = 135/135 (100%)
Query: 1 MAQQGQQGQMASGDSNLNFRMVAEIQNVEGQNLQEQVCPEPIFRFFRENKVEIASAITRP 60
MAQQGQQGQMASGDSNLNFRMVAEIQNVEGQNLQEQVCPEPIFRFFRENKVEIASAITRP
Sbjct: 1 MAQQGQQGQMASGDSNLNFRMVAEIQNVEGQNLQEQVCPEPIFRFFRENKVEIASAITRP 60
Query: 61 FPFLMGLRDRSFISEQMYEHFQEAFRNLVPVTRVMYCVLSELEKTFGWSHLEALFSRINL 120
FPFLMGLRDRSFISEQMYEHFQEAFRNLVPVTRVMYCVLSELEKTFGWSHLEALFSRINL
Sbjct: 61 FPFLMGLRDRSFISEQMYEHFQEAFRNLVPVTRVMYCVLSELEKTFGWSHLEALFSRINL 120
Query: 121 MAYPDLNEIYRSFQN 135
MAYPDLNEIYRSFQN
Sbjct: 121 MAYPDLNEIYRSFQN 135
>gi|134133279 SP140 nuclear body protein-like [Homo sapiens]
Length = 580
Score = 117 bits (294), Expect = 4e-27
Identities = 57/107 (53%), Positives = 80/107 (74%)
Query: 29 EGQNLQEQVCPEPIFRFFRENKVEIASAITRPFPFLMGLRDRSFISEQMYEHFQEAFRNL 88
E Q++ E + + +F+ F+ +K+EI++AI + FPFL GLRDR I+ +M+E +++ RNL
Sbjct: 40 EDQDVDEGLVYDTVFKHFKRHKLEISNAIKKTFPFLEGLRDRELITNKMFEDSEDSCRNL 99
Query: 89 VPVTRVMYCVLSELEKTFGWSHLEALFSRINLMAYPDLNEIYRSFQN 135
VPV RV+Y VLSELEKTF S LEALFS +N+ YPDL IY+SF+N
Sbjct: 100 VPVQRVVYNVLSELEKTFNLSVLEALFSEVNMQEYPDLIHIYKSFKN 146
>gi|122939208 nuclear antigen Sp100 isoform 1 [Homo sapiens]
Length = 885
Score = 117 bits (292), Expect = 6e-27
Identities = 57/107 (53%), Positives = 78/107 (72%)
Query: 29 EGQNLQEQVCPEPIFRFFRENKVEIASAITRPFPFLMGLRDRSFISEQMYEHFQEAFRNL 88
E Q + +++ + +F+ F+ NKVEI++AI + FPFL GLRDR I+ +M+E Q++ RNL
Sbjct: 40 EDQGVDDRLLYDIVFKHFKRNKVEISNAIKKTFPFLEGLRDRDLITNKMFEDSQDSCRNL 99
Query: 89 VPVTRVMYCVLSELEKTFGWSHLEALFSRINLMAYPDLNEIYRSFQN 135
VPV RV+Y VLSELEKTF LEALFS +N+ YPDL IY+ F+N
Sbjct: 100 VPVQRVVYNVLSELEKTFNLPVLEALFSDVNMQEYPDLIHIYKGFEN 146
>gi|19923236 nuclear antigen Sp100 isoform 2 [Homo sapiens]
Length = 879
Score = 117 bits (292), Expect = 6e-27
Identities = 57/107 (53%), Positives = 78/107 (72%)
Query: 29 EGQNLQEQVCPEPIFRFFRENKVEIASAITRPFPFLMGLRDRSFISEQMYEHFQEAFRNL 88
E Q + +++ + +F+ F+ NKVEI++AI + FPFL GLRDR I+ +M+E Q++ RNL
Sbjct: 40 EDQGVDDRLLYDIVFKHFKRNKVEISNAIKKTFPFLEGLRDRDLITNKMFEDSQDSCRNL 99
Query: 89 VPVTRVMYCVLSELEKTFGWSHLEALFSRINLMAYPDLNEIYRSFQN 135
VPV RV+Y VLSELEKTF LEALFS +N+ YPDL IY+ F+N
Sbjct: 100 VPVQRVVYNVLSELEKTFNLPVLEALFSDVNMQEYPDLIHIYKGFEN 146
>gi|190343010 SP110 nuclear body protein isoform a [Homo sapiens]
Length = 689
Score = 96.7 bits (239), Expect = 9e-21
Identities = 50/100 (50%), Positives = 68/100 (68%)
Query: 40 EPIFRFFRENKVEIASAITRPFPFLMGLRDRSFISEQMYEHFQEAFRNLVPVTRVMYCVL 99
E +F+ F K+ IA AI +PFPF GL D S I+++MY EA RNL+PV+RV++ +L
Sbjct: 10 EALFQHFMHQKLGIAYAIHKPFPFFEGLLDNSIITKRMYMESLEACRNLIPVSRVVHNIL 69
Query: 100 SELEKTFGWSHLEALFSRINLMAYPDLNEIYRSFQNENLS 139
++LE+TF S L LFS+INL YP+L IYRSF+ S
Sbjct: 70 TQLERTFNLSLLVTLFSQINLREYPNLVTIYRSFKRVGAS 109
>gi|190343008 SP110 nuclear body protein isoform b [Homo sapiens]
Length = 549
Score = 96.7 bits (239), Expect = 9e-21
Identities = 50/100 (50%), Positives = 68/100 (68%)
Query: 40 EPIFRFFRENKVEIASAITRPFPFLMGLRDRSFISEQMYEHFQEAFRNLVPVTRVMYCVL 99
E +F+ F K+ IA AI +PFPF GL D S I+++MY EA RNL+PV+RV++ +L
Sbjct: 10 EALFQHFMHQKLGIAYAIHKPFPFFEGLLDNSIITKRMYMESLEACRNLIPVSRVVHNIL 69
Query: 100 SELEKTFGWSHLEALFSRINLMAYPDLNEIYRSFQNENLS 139
++LE+TF S L LFS+INL YP+L IYRSF+ S
Sbjct: 70 TQLERTFNLSLLVTLFSQINLREYPNLVTIYRSFKRVGAS 109
>gi|190343006 SP110 nuclear body protein isoform c [Homo sapiens]
Length = 713
Score = 96.7 bits (239), Expect = 9e-21
Identities = 50/100 (50%), Positives = 68/100 (68%)
Query: 40 EPIFRFFRENKVEIASAITRPFPFLMGLRDRSFISEQMYEHFQEAFRNLVPVTRVMYCVL 99
E +F+ F K+ IA AI +PFPF GL D S I+++MY EA RNL+PV+RV++ +L
Sbjct: 10 EALFQHFMHQKLGIAYAIHKPFPFFEGLLDNSIITKRMYMESLEACRNLIPVSRVVHNIL 69
Query: 100 SELEKTFGWSHLEALFSRINLMAYPDLNEIYRSFQNENLS 139
++LE+TF S L LFS+INL YP+L IYRSF+ S
Sbjct: 70 TQLERTFNLSLLVTLFSQINLREYPNLVTIYRSFKRVGAS 109
>gi|4557291 autoimmune regulator isoform 1 [Homo sapiens]
Length = 545
Score = 30.0 bits (66), Expect = 1.0
Identities = 28/98 (28%), Positives = 39/98 (39%), Gaps = 8/98 (8%)
Query: 44 RFFRENKVEIASAITRPFPFLMGLRDRSFISEQMYEHFQEA--FRNLVPVTRVMYCVLSE 101
R R ++ EIA A+ FP L L D + E + FQE + + + +LS
Sbjct: 9 RLLRLHRTEIAVAVDSAFPLLHALADHDVVPE---DKFQETLHLKEKEGCPQAFHALLSW 65
Query: 102 L---EKTFGWSHLEALFSRINLMAYPDLNEIYRSFQNE 136
L + T LF NL Y L I SF +
Sbjct: 66 LLTQDSTAILDFWRVLFKDYNLERYGRLQPILDSFPKD 103
>gi|194097432 hypothetical protein LOC285966 B [Homo sapiens]
Length = 564
Score = 29.3 bits (64), Expect = 1.8
Identities = 15/39 (38%), Positives = 18/39 (46%)
Query: 25 IQNVEGQNLQEQVCPEPIFRFFRENKVEIASAITRPFPF 63
I V NLQ PEP+ R + E +A PFPF
Sbjct: 389 ILTVPTTNLQALKDPEPVLRLWDEMMQAVARLAAEPFPF 427
>gi|194097428 hypothetical protein LOC285966 A [Homo sapiens]
Length = 845
Score = 29.3 bits (64), Expect = 1.8
Identities = 15/39 (38%), Positives = 18/39 (46%)
Query: 25 IQNVEGQNLQEQVCPEPIFRFFRENKVEIASAITRPFPF 63
I V NLQ PEP+ R + E +A PFPF
Sbjct: 670 ILTVPTTNLQALKDPEPVLRLWDEMMQAVARLAAEPFPF 708
>gi|194097425 hypothetical protein LOC285966 A [Homo sapiens]
Length = 845
Score = 29.3 bits (64), Expect = 1.8
Identities = 15/39 (38%), Positives = 18/39 (46%)
Query: 25 IQNVEGQNLQEQVCPEPIFRFFRENKVEIASAITRPFPF 63
I V NLQ PEP+ R + E +A PFPF
Sbjct: 670 ILTVPTTNLQALKDPEPVLRLWDEMMQAVARLAAEPFPF 708
>gi|148746183 ubiquitin specific protease 35 [Homo sapiens]
Length = 1018
Score = 28.9 bits (63), Expect = 2.3
Identities = 24/91 (26%), Positives = 43/91 (47%), Gaps = 7/91 (7%)
Query: 78 YEHFQEAFRNLVPVTRVMYCVLSELEKTFGWSHLEALFSRINLM-----AYPDLNE-IYR 131
++H EAF L+P M L + + G S LE L ++ M +PDL E +
Sbjct: 337 FQHSHEAFHLLLPHIPPMVASLVKEDSNSGTSCLEQLAELVHCMVFRFPGFPDLYEPVME 396
Query: 132 SFQNENLSSSAVLCQLVSPNKDWRSHEESLA 162
+ ++ ++ + + QL+ + W S + LA
Sbjct: 397 AIKDLHVPNEDRIKQLLGQDA-WTSQKSELA 426
>gi|21264623 suppression of tumorigenicity 7-like isoform 4 [Homo
sapiens]
Length = 555
Score = 28.5 bits (62), Expect = 3.0
Identities = 12/36 (33%), Positives = 19/36 (52%)
Query: 110 HLEALFSRINLMAYPDLNEIYRSFQNENLSSSAVLC 145
H L S + L AYPD+ + + + +L SA +C
Sbjct: 332 HENLLESLLELQAYPDVQAVLAKYDDISLPKSAAIC 367
>gi|21264621 suppression of tumorigenicity 7-like isoform 3 [Homo
sapiens]
Length = 544
Score = 28.5 bits (62), Expect = 3.0
Identities = 12/36 (33%), Positives = 19/36 (52%)
Query: 110 HLEALFSRINLMAYPDLNEIYRSFQNENLSSSAVLC 145
H L S + L AYPD+ + + + +L SA +C
Sbjct: 332 HENLLESLLELQAYPDVQAVLAKYDDISLPKSAAIC 367
>gi|21264619 suppression of tumorigenicity 7-like isoform 2 [Homo
sapiens]
Length = 558
Score = 28.5 bits (62), Expect = 3.0
Identities = 12/36 (33%), Positives = 19/36 (52%)
Query: 110 HLEALFSRINLMAYPDLNEIYRSFQNENLSSSAVLC 145
H L S + L AYPD+ + + + +L SA +C
Sbjct: 315 HENLLESLLELQAYPDVQAVLAKYDDISLPKSAAIC 350
>gi|20270257 suppression of tumorigenicity 7-like isoform 1 [Homo
sapiens]
Length = 575
Score = 28.5 bits (62), Expect = 3.0
Identities = 12/36 (33%), Positives = 19/36 (52%)
Query: 110 HLEALFSRINLMAYPDLNEIYRSFQNENLSSSAVLC 145
H L S + L AYPD+ + + + +L SA +C
Sbjct: 332 HENLLESLLELQAYPDVQAVLAKYDDISLPKSAAIC 367
>gi|110832839 ATP-binding cassette, sub-family C, member 9 isoform
SUR2A-delta-14 [Homo sapiens]
Length = 1513
Score = 27.3 bits (59), Expect = 6.7
Identities = 19/59 (32%), Positives = 31/59 (52%), Gaps = 8/59 (13%)
Query: 8 GQMASGDSNLNFRMVAEIQNVEGQ----NLQEQVCPEPIFRFFR-ENKVEIASAITRPF 61
GQ+ G S+L ++ E+Q +EG+ N+ E EP F R N+ +A A +P+
Sbjct: 669 GQVGCGKSSLLLAILGEMQTLEGKVHWSNVNES---EPSFEATRSRNRYSVAYAAQKPW 724
>gi|110832835 ATP-binding cassette, sub-family C, member 9 isoform
SUR2A [Homo sapiens]
Length = 1549
Score = 27.3 bits (59), Expect = 6.7
Identities = 19/59 (32%), Positives = 31/59 (52%), Gaps = 8/59 (13%)
Query: 8 GQMASGDSNLNFRMVAEIQNVEGQ----NLQEQVCPEPIFRFFR-ENKVEIASAITRPF 61
GQ+ G S+L ++ E+Q +EG+ N+ E EP F R N+ +A A +P+
Sbjct: 705 GQVGCGKSSLLLAILGEMQTLEGKVHWSNVNES---EPSFEATRSRNRYSVAYAAQKPW 760
>gi|110832837 ATP-binding cassette, sub-family C, member 9 isoform
SUR2B [Homo sapiens]
Length = 1549
Score = 27.3 bits (59), Expect = 6.7
Identities = 19/59 (32%), Positives = 31/59 (52%), Gaps = 8/59 (13%)
Query: 8 GQMASGDSNLNFRMVAEIQNVEGQ----NLQEQVCPEPIFRFFR-ENKVEIASAITRPF 61
GQ+ G S+L ++ E+Q +EG+ N+ E EP F R N+ +A A +P+
Sbjct: 705 GQVGCGKSSLLLAILGEMQTLEGKVHWSNVNES---EPSFEATRSRNRYSVAYAAQKPW 760
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.133 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,183,746
Number of Sequences: 37866
Number of extensions: 239985
Number of successful extensions: 543
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 526
Number of HSP's gapped (non-prelim): 21
length of query: 172
length of database: 18,247,518
effective HSP length: 95
effective length of query: 77
effective length of database: 14,650,248
effective search space: 1128069096
effective search space used: 1128069096
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.