BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|52426787 oligodendrocyte myelin glycoprotein [Homo sapiens] (440 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|52426787 oligodendrocyte myelin glycoprotein [Homo sapiens] 888 0.0 gi|45505137 podocan [Homo sapiens] 87 2e-17 gi|226342935 podocan-like 1 isoform 3 [Homo sapiens] 87 4e-17 gi|226342933 podocan-like 1 isoform 2 [Homo sapiens] 82 1e-15 gi|226342931 podocan-like 1 isoform 1 [Homo sapiens] 82 1e-15 gi|7019381 fibronectin leucine rich transmembrane protein 2 [Hom... 79 6e-15 gi|205277468 leucine rich repeat containing 15 isoform a [Homo s... 78 2e-14 gi|18677767 leucine rich repeat containing 15 isoform b [Homo sa... 78 2e-14 gi|150417978 platelet glycoprotein Ib alpha polypeptide precurso... 77 2e-14 gi|34577057 fibronectin leucine rich transmembrane protein 1 [Ho... 77 2e-14 gi|238908508 leucine-rich repeat and death domain-containing pro... 77 3e-14 gi|156139147 leucine rich repeat transmembrane neuronal 4 isofor... 77 3e-14 gi|197927168 leucine rich repeat transmembrane neuronal 4 isofor... 77 3e-14 gi|7662102 leucine rich repeat transmembrane neuronal 2 [Homo sa... 76 7e-14 gi|109809759 leucine rich repeat transmembrane neuronal 3 [Homo ... 75 1e-13 gi|198041768 synleurin [Homo sapiens] 74 2e-13 gi|4504379 leucine-rich repeat-containing G protein-coupled rece... 73 4e-13 gi|5729718 trophoblast glycoprotein [Homo sapiens] 73 6e-13 gi|41349454 proline arginine-rich end leucine-rich repeat protei... 72 1e-12 gi|4506041 proline arginine-rich end leucine-rich repeat protein... 72 1e-12 gi|194306623 immunoglobulin superfamily containing leucine-rich ... 71 2e-12 gi|194306621 immunoglobulin superfamily containing leucine-rich ... 71 2e-12 gi|39930401 immunoglobulin superfamily containing leucine-rich r... 71 2e-12 gi|194306618 immunoglobulin superfamily containing leucine-rich ... 71 2e-12 gi|38490688 immunoglobulin superfamily, member 10 [Homo sapiens] 71 2e-12 gi|221136985 SLIT and NTRK-like family, member 2 [Homo sapiens] 70 3e-12 gi|221136981 SLIT and NTRK-like family, member 2 [Homo sapiens] 70 3e-12 gi|221136977 SLIT and NTRK-like family, member 2 [Homo sapiens] 70 3e-12 gi|221136973 SLIT and NTRK-like family, member 2 [Homo sapiens] 70 3e-12 gi|221136969 SLIT and NTRK-like family, member 2 [Homo sapiens] 70 3e-12 >gi|52426787 oligodendrocyte myelin glycoprotein [Homo sapiens] Length = 440 Score = 888 bits (2294), Expect = 0.0 Identities = 440/440 (100%), Positives = 440/440 (100%) Query: 1 MEYQILKMSLCLFILLFLTPGILCICPLQCICTERHRHVDCSGRNLSTLPSGLQENIIHL 60 MEYQILKMSLCLFILLFLTPGILCICPLQCICTERHRHVDCSGRNLSTLPSGLQENIIHL Sbjct: 1 MEYQILKMSLCLFILLFLTPGILCICPLQCICTERHRHVDCSGRNLSTLPSGLQENIIHL 60 Query: 61 NLSYNHFTDLHNQLTQYTNLRTLDISNNRLESLPAHLPRSLWNMSAANNNIKLLDKSDTA 120 NLSYNHFTDLHNQLTQYTNLRTLDISNNRLESLPAHLPRSLWNMSAANNNIKLLDKSDTA Sbjct: 61 NLSYNHFTDLHNQLTQYTNLRTLDISNNRLESLPAHLPRSLWNMSAANNNIKLLDKSDTA 120 Query: 121 YQWNLKYLDVSKNMLEKVVLIKNTLRSLEVLNLSSNKLWTVPTNMPSKLHIVDLSNNSLT 180 YQWNLKYLDVSKNMLEKVVLIKNTLRSLEVLNLSSNKLWTVPTNMPSKLHIVDLSNNSLT Sbjct: 121 YQWNLKYLDVSKNMLEKVVLIKNTLRSLEVLNLSSNKLWTVPTNMPSKLHIVDLSNNSLT 180 Query: 181 QILPGTLINLTNLTHLYLHNNKFTFIPDQSFDQLFQLQEITLYNNRWSCDHKQNITYLLK 240 QILPGTLINLTNLTHLYLHNNKFTFIPDQSFDQLFQLQEITLYNNRWSCDHKQNITYLLK Sbjct: 181 QILPGTLINLTNLTHLYLHNNKFTFIPDQSFDQLFQLQEITLYNNRWSCDHKQNITYLLK 240 Query: 241 WMMETKAHVIGTPCSTQISSLKEHNMYPTPSGFTSSLFTVSGMQTVDTINSLSVVTQPKV 300 WMMETKAHVIGTPCSTQISSLKEHNMYPTPSGFTSSLFTVSGMQTVDTINSLSVVTQPKV Sbjct: 241 WMMETKAHVIGTPCSTQISSLKEHNMYPTPSGFTSSLFTVSGMQTVDTINSLSVVTQPKV 300 Query: 301 TKIPKQYRTKETTFGATLSKDTTFTSTDKAFVPYPEDTSTETINSHEAAAATLTIHLQDG 360 TKIPKQYRTKETTFGATLSKDTTFTSTDKAFVPYPEDTSTETINSHEAAAATLTIHLQDG Sbjct: 301 TKIPKQYRTKETTFGATLSKDTTFTSTDKAFVPYPEDTSTETINSHEAAAATLTIHLQDG 360 Query: 361 MVTNTSLTSSTKSSPTPMTLSITSGMPNNFSEMPQQSTTLNLWREETTTNVKTPLPSVAN 420 MVTNTSLTSSTKSSPTPMTLSITSGMPNNFSEMPQQSTTLNLWREETTTNVKTPLPSVAN Sbjct: 361 MVTNTSLTSSTKSSPTPMTLSITSGMPNNFSEMPQQSTTLNLWREETTTNVKTPLPSVAN 420 Query: 421 AWKVNASFLLLLNVVVMLAV 440 AWKVNASFLLLLNVVVMLAV Sbjct: 421 AWKVNASFLLLLNVVVMLAV 440 >gi|45505137 podocan [Homo sapiens] Length = 661 Score = 87.4 bits (215), Expect = 2e-17 Identities = 71/235 (30%), Positives = 108/235 (45%), Gaps = 33/235 (14%) Query: 26 CPLQCICTERHRHVDCSGRNLSTLPSGLQENIIHLNLSYNHFTDLH-------------- 71 CP C C++ VDC G +L P L E+ HL+L N ++ Sbjct: 116 CPRDCACSQEGV-VDCGGIDLREFPGDLPEHTNHLSLQNNQLEKIYPEELSRLHRLETLN 174 Query: 72 ---NQLTQ----------YTNLRTLDISNNRLESLPAHLPRSLWNMSAANNNIKLLDKSD 118 N+LT TNL L ++NN+L P LP +L ++ A N + + Sbjct: 175 LQNNRLTSRGLPEKAFEHLTNLNYLYLANNKLTLAPRFLPNALISVDFAANYLTKIYGLT 234 Query: 119 TAYQWNLKYLDVSKNMLEKVVLIKNTLR---SLEVLNLSSNKLWTVPTNMPSKLHIVDLS 175 + NL+ + + N L L N ++EVL LSSN L VP ++P L+ + L Sbjct: 235 FGQKPNLRSVYLHNNKLADAGLPDNMFNGSSNVEVLILSSNFLRHVPKHLPPALYKLHLK 294 Query: 176 NNSLTQILPGTLINLTNLTHLYLHNNKFT--FIPDQSFDQLFQLQEITLYNNRWS 228 NN L +I PG L++L LYL NN T + +++F +L L+ + L +N S Sbjct: 295 NNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLS 349 Score = 80.5 bits (197), Expect = 3e-15 Identities = 54/195 (27%), Positives = 95/195 (48%), Gaps = 30/195 (15%) Query: 38 HVDCSGRNLSTLPSGLQENIIHLNLSYN----------------HFTDLH-NQLTQY--- 77 ++D S NLS +P+GL +++ L+L N + LH NQL + Sbjct: 340 YLDLSSNNLSRVPAGLPRSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLREQGIH 399 Query: 78 -------TNLRTLDISNNRLESLPAHLPRSLWNMSAANNNIKLLDKSDTAYQWNLKYLDV 130 L T+ + NN LE +P+ LPR + + +N I + + D A + L+ L++ Sbjct: 400 PLAFQGLKRLHTVHLYNNALERVPSGLPRRVRTLMILHNQITGIGREDFATTYFLEELNL 459 Query: 131 SKNMLEKVVLIKNTLRSLEVL---NLSSNKLWTVPTNMPSKLHIVDLSNNSLTQILPGTL 187 S N + + ++ R L +L +LS N+L T+P +P +H++ + N L + G L Sbjct: 460 SYNRITSPQVHRDAFRKLRLLRSLDLSGNRLHTLPPGLPRNVHVLKVKRNELAALARGAL 519 Query: 188 INLTNLTHLYLHNNK 202 + + L LYL +N+ Sbjct: 520 VGMAQLRELYLTSNR 534 Score = 73.6 bits (179), Expect = 3e-13 Identities = 55/185 (29%), Positives = 88/185 (47%), Gaps = 8/185 (4%) Query: 49 LPSGLQENIIHLNLSYNHFTDL---HNQLTQYTNLRTLDISNNRLESLPAHLPRSLWNMS 105 L G + N+ + L N D N +N+ L +S+N L +P HLP +L+ + Sbjct: 233 LTFGQKPNLRSVYLHNNKLADAGLPDNMFNGSSNVEVLILSSNFLRHVPKHLPPALYKLH 292 Query: 106 AANNNIKLLDKSDTAYQWNLKYLDVSKNMLEKVVLIKNT---LRSLEVLNLSSNKLWTVP 162 NN ++ + + +L+ L + N L L T L SLE L+LSSN L VP Sbjct: 293 LKNNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVP 352 Query: 163 TNMPSKLHIVDLSNNSLTQILPGTLINLTNLTHLYLHNNKF--TFIPDQSFDQLFQLQEI 220 +P L ++ L N++ + L + +L +L LH+N+ I +F L +L + Sbjct: 353 AGLPRSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAFQGLKRLHTV 412 Query: 221 TLYNN 225 LYNN Sbjct: 413 HLYNN 417 Score = 71.2 bits (173), Expect = 2e-12 Identities = 50/174 (28%), Positives = 83/174 (47%), Gaps = 8/174 (4%) Query: 60 LNLSYNHFTD--LHNQLTQYTNL-RTLDISNNRLESLPAHLPRSLWNMSAANNNIKLLDK 116 LNLSYN T +H + L R+LD+S NRL +LP LPR++ + N + L + Sbjct: 457 LNLSYNRITSPQVHRDAFRKLRLLRSLDLSGNRLHTLPPGLPRNVHVLKVKRNELAALAR 516 Query: 117 SDTAYQWNLKYLDVSKNMLEKVVLIKNT---LRSLEVLNLSSNKLWTVPTNMPSKLHIVD 173 L+ L ++ N L L L L++L+++ N+L +P +P L + Sbjct: 517 GALVGMAQLRELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEIPEGLPESLEYLY 576 Query: 174 LSNNSLTQILPGTLINLTNLTHLYLHNNKFTF--IPDQSFDQLFQLQEITLYNN 225 L NN ++ + + NL ++L NK + D +F +L LQ + + N Sbjct: 577 LQNNKISAVPANAFDSTPNLKGIFLRFNKLAVGSVVDSAFRRLKHLQVLDIEGN 630 >gi|226342935 podocan-like 1 isoform 3 [Homo sapiens] Length = 421 Score = 86.7 bits (213), Expect = 4e-17 Identities = 69/214 (32%), Positives = 101/214 (47%), Gaps = 15/214 (7%) Query: 26 CPLQCICTERHRHVDCSGRNLSTLPSGLQENIIHLNLSYNHFTDL-HNQLTQYTNLRTLD 84 CPL+C C R VDC G +L P + HL+L N +L +N+L++ + LRTL+ Sbjct: 44 CPLRCSCP-RVDTVDCDGLDLRVFPDNITRAAQHLSLQNNQLQELPYNELSRLSGLRTLN 102 Query: 85 ISNNRL--ESLPAHLPRSLWNMSAA------NNNIKLLDKSDTAYQWNLKYLDVSKNMLE 136 + NN + E LP SL + NN I + + + Q L+ L + N L Sbjct: 103 LHNNLISSEGLPDEAFESLTQLQHLCVAHNKNNLISKVPRGALSRQTQLRELYLQHNQLT 162 Query: 137 KVVLIKNT---LRSLEVLNLSSNKLWTVPTNMPSKLHIVDLSNNSLTQILPGTLINLTNL 193 L T L SLE L+LS N+L TVP +P L I+ L N + Q+ L L Sbjct: 163 DSGLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGL 222 Query: 194 THLYLHNNKF--TFIPDQSFDQLFQLQEITLYNN 225 +L L +N+ + +P + L L + LY N Sbjct: 223 RYLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGN 256 Score = 48.5 bits (114), Expect = 1e-05 Identities = 39/136 (28%), Positives = 57/136 (41%), Gaps = 8/136 (5%) Query: 36 HRHVDCSGRNLSTLPSGLQENIIHLNLSYNHFTDL---HNQLTQYTNLRTLDISNNRLES 92 H HV G GL E LNL+YN H + LR+LD++ N+L Sbjct: 276 HNHVAALGARDLVATPGLTE----LNLAYNRLASARVHHRAFRRLRALRSLDLAGNQLTR 331 Query: 93 LPAHLPRSLWNMSAANNNIKLLDKSDTAYQWNLKYLDVSKNMLEKVVLIKNTLRSLEVLN 152 LP LP L + N +++L+ A L+ L ++ N L + T L+ L Sbjct: 332 LPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLRELSLAHNRLRVGDIGPGTWHELQALQ 391 Query: 153 LSSNKL-WTVPTNMPS 167 + + TVP PS Sbjct: 392 VRHRLVSHTVPRAPPS 407 Score = 40.8 bits (94), Expect = 0.002 Identities = 26/102 (25%), Positives = 49/102 (48%), Gaps = 2/102 (1%) Query: 127 YLDVSKNMLEKVVLIKNTLRSLEVLNLSSNKLWTVPTNMPSKLHIVDLSNNSLTQILPGT 186 +L S L + ++ + ++ ++ L P N+ + L NN L ++ Sbjct: 32 HLGESLQPLPRACPLRCSCPRVDTVDCDGLDLRVFPDNITRAAQHLSLQNNQLQELPYNE 91 Query: 187 LINLTNLTHLYLHNNKFTF--IPDQSFDQLFQLQEITLYNNR 226 L L+ L L LHNN + +PD++F+ L QLQ + + +N+ Sbjct: 92 LSRLSGLRTLNLHNNLISSEGLPDEAFESLTQLQHLCVAHNK 133 Score = 34.3 bits (77), Expect = 0.23 Identities = 31/100 (31%), Positives = 53/100 (53%), Gaps = 8/100 (8%) Query: 135 LEKVVLIKNTLRSLEVLNLSSNKLWTVPTNMPSKL---HIVDLSNNSLT-QILPGTLI-N 189 L+ V N R+ + L+L +N+L +P N S+L ++L NN ++ + LP + Sbjct: 61 LDLRVFPDNITRAAQHLSLQNNQLQELPYNELSRLSGLRTLNLHNNLISSEGLPDEAFES 120 Query: 190 LTNLTHLYLHNNKFTFI---PDQSFDQLFQLQEITLYNNR 226 LT L HL + +NK I P + + QL+E+ L +N+ Sbjct: 121 LTQLQHLCVAHNKNNLISKVPRGALSRQTQLRELYLQHNQ 160 >gi|226342933 podocan-like 1 isoform 2 [Homo sapiens] Length = 510 Score = 81.6 bits (200), Expect = 1e-15 Identities = 65/233 (27%), Positives = 105/233 (45%), Gaps = 33/233 (14%) Query: 26 CPLQCICTERHRHVDCSGRNLSTLPSGLQENIIHLNLSYNHFTDL-HNQLTQYTNLRTLD 84 CPL+C C R VDC G +L P + HL+L N +L +N+L++ + LRTL+ Sbjct: 44 CPLRCSCP-RVDTVDCDGLDLRVFPDNITRAAQHLSLQNNQLQELPYNELSRLSGLRTLN 102 Query: 85 ISNNRLES--------------------------LPAHLPRSLWNMSAANNNIKLLDKSD 118 + NN + S P LPRSL A N + + Sbjct: 103 LHNNLISSEGLPDEAFESLTQLQHLCVAHNKLSVAPQFLPRSLRVADLAANQVMEIFPLT 162 Query: 119 TAYQWNLKYLDVSKNMLEKVVLIKNTLRSLEV---LNLSSNKLWTVPTNMPSKLHIVDLS 175 + L+ + + N L L + R E L+LS+N+L +P ++P L + L Sbjct: 163 FGEKPALRSVYLHNNQLSNAGLPPDAFRGSEAIATLSLSNNQLSYLPPSLPPSLERLHLQ 222 Query: 176 NNSLTQILPGTLINLTNLTHLYLHNNKFT--FIPDQSFDQLFQLQEITLYNNR 226 NN ++++ G L T L LYL +N+ T + +F +L L+ + L +N+ Sbjct: 223 NNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQ 275 Score = 69.7 bits (169), Expect = 5e-12 Identities = 51/151 (33%), Positives = 73/151 (48%), Gaps = 5/151 (3%) Query: 80 LRTLDISNNRLESLPAHLPRSLWNMSAANNNIKLLDKSDTAYQWNLKYLDVSKNMLEKVV 139 + TL +SNN+L LP LP SL + NN I + + + Q L+ L + N L Sbjct: 195 IATLSLSNNQLSYLPPSLPPSLERLHLQNNLISKVPRGALSRQTQLRELYLQHNQLTDSG 254 Query: 140 LIKNT---LRSLEVLNLSSNKLWTVPTNMPSKLHIVDLSNNSLTQILPGTLINLTNLTHL 196 L T L SLE L+LS N+L TVP +P L I+ L N + Q+ L L +L Sbjct: 255 LDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYL 314 Query: 197 YLHNNKF--TFIPDQSFDQLFQLQEITLYNN 225 L +N+ + +P + L L + LY N Sbjct: 315 LLQHNQLGSSGLPAGALRPLRGLHTLHLYGN 345 Score = 63.2 bits (152), Expect = 5e-10 Identities = 54/192 (28%), Positives = 90/192 (46%), Gaps = 11/192 (5%) Query: 46 LSTLPSGL---QENIIHLNLSYNHFTDLHNQLTQYTNLRTL---DISNNRLESLPAHLPR 99 +S +P G Q + L L +N TD T ++ L +L D+S+N+L ++PA LPR Sbjct: 226 ISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGLPR 285 Query: 100 SLWNMSAANNNIKLLDKSDTAYQWNLKYLDVSKNMLEKVVL---IKNTLRSLEVLNLSSN 156 +L + N I+ ++ + L+YL + N L L LR L L+L N Sbjct: 286 TLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGN 345 Query: 157 KLWTVPTNMPSKLHIVDLSNNSLTQILPGTLINLTNLTHLYLHNNKFTF--IPDQSFDQL 214 L VP +P +L + L +N + + L+ LT L L N+ + ++F +L Sbjct: 346 GLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRAFRRL 405 Query: 215 FQLQEITLYNNR 226 L+ + L N+ Sbjct: 406 RALRSLDLAGNQ 417 Score = 60.8 bits (146), Expect = 2e-09 Identities = 51/195 (26%), Positives = 81/195 (41%), Gaps = 30/195 (15%) Query: 38 HVDCSGRNLSTLPSGLQENIIHLNLSYNHFTDL-----------------HNQ------- 73 ++D S L+T+P+GL + L+L N + HNQ Sbjct: 268 YLDLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLP 327 Query: 74 ---LTQYTNLRTLDISNNRLESLPAHLPRSLWNMSAANNNIKLLDKSDTAYQWNLKYLDV 130 L L TL + N L+ +P LPR L + +N++ L D L L++ Sbjct: 328 AGALRPLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNL 387 Query: 131 SKNMLEKVVLIKNT---LRSLEVLNLSSNKLWTVPTNMPSKLHIVDLSNNSLTQILPGTL 187 + N L + LR+L L+L+ N+L +P +P+ L + L N L + P L Sbjct: 388 AYNRLASARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPL 447 Query: 188 INLTNLTHLYLHNNK 202 L L L L +N+ Sbjct: 448 AGLDQLRELSLAHNR 462 Score = 48.5 bits (114), Expect = 1e-05 Identities = 39/136 (28%), Positives = 57/136 (41%), Gaps = 8/136 (5%) Query: 36 HRHVDCSGRNLSTLPSGLQENIIHLNLSYNHFTDL---HNQLTQYTNLRTLDISNNRLES 92 H HV G GL E LNL+YN H + LR+LD++ N+L Sbjct: 365 HNHVAALGARDLVATPGLTE----LNLAYNRLASARVHHRAFRRLRALRSLDLAGNQLTR 420 Query: 93 LPAHLPRSLWNMSAANNNIKLLDKSDTAYQWNLKYLDVSKNMLEKVVLIKNTLRSLEVLN 152 LP LP L + N +++L+ A L+ L ++ N L + T L+ L Sbjct: 421 LPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLRELSLAHNRLRVGDIGPGTWHELQALQ 480 Query: 153 LSSNKL-WTVPTNMPS 167 + + TVP PS Sbjct: 481 VRHRLVSHTVPRAPPS 496 Score = 41.6 bits (96), Expect = 0.001 Identities = 27/104 (25%), Positives = 50/104 (48%), Gaps = 2/104 (1%) Query: 127 YLDVSKNMLEKVVLIKNTLRSLEVLNLSSNKLWTVPTNMPSKLHIVDLSNNSLTQILPGT 186 +L S L + ++ + ++ ++ L P N+ + L NN L ++ Sbjct: 32 HLGESLQPLPRACPLRCSCPRVDTVDCDGLDLRVFPDNITRAAQHLSLQNNQLQELPYNE 91 Query: 187 LINLTNLTHLYLHNNKFTF--IPDQSFDQLFQLQEITLYNNRWS 228 L L+ L L LHNN + +PD++F+ L QLQ + + +N+ S Sbjct: 92 LSRLSGLRTLNLHNNLISSEGLPDEAFESLTQLQHLCVAHNKLS 135 >gi|226342931 podocan-like 1 isoform 1 [Homo sapiens] Length = 512 Score = 81.6 bits (200), Expect = 1e-15 Identities = 65/233 (27%), Positives = 105/233 (45%), Gaps = 33/233 (14%) Query: 26 CPLQCICTERHRHVDCSGRNLSTLPSGLQENIIHLNLSYNHFTDL-HNQLTQYTNLRTLD 84 CPL+C C R VDC G +L P + HL+L N +L +N+L++ + LRTL+ Sbjct: 46 CPLRCSCP-RVDTVDCDGLDLRVFPDNITRAAQHLSLQNNQLQELPYNELSRLSGLRTLN 104 Query: 85 ISNNRLES--------------------------LPAHLPRSLWNMSAANNNIKLLDKSD 118 + NN + S P LPRSL A N + + Sbjct: 105 LHNNLISSEGLPDEAFESLTQLQHLCVAHNKLSVAPQFLPRSLRVADLAANQVMEIFPLT 164 Query: 119 TAYQWNLKYLDVSKNMLEKVVLIKNTLRSLEV---LNLSSNKLWTVPTNMPSKLHIVDLS 175 + L+ + + N L L + R E L+LS+N+L +P ++P L + L Sbjct: 165 FGEKPALRSVYLHNNQLSNAGLPPDAFRGSEAIATLSLSNNQLSYLPPSLPPSLERLHLQ 224 Query: 176 NNSLTQILPGTLINLTNLTHLYLHNNKFT--FIPDQSFDQLFQLQEITLYNNR 226 NN ++++ G L T L LYL +N+ T + +F +L L+ + L +N+ Sbjct: 225 NNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQ 277 Score = 69.7 bits (169), Expect = 5e-12 Identities = 51/151 (33%), Positives = 73/151 (48%), Gaps = 5/151 (3%) Query: 80 LRTLDISNNRLESLPAHLPRSLWNMSAANNNIKLLDKSDTAYQWNLKYLDVSKNMLEKVV 139 + TL +SNN+L LP LP SL + NN I + + + Q L+ L + N L Sbjct: 197 IATLSLSNNQLSYLPPSLPPSLERLHLQNNLISKVPRGALSRQTQLRELYLQHNQLTDSG 256 Query: 140 LIKNT---LRSLEVLNLSSNKLWTVPTNMPSKLHIVDLSNNSLTQILPGTLINLTNLTHL 196 L T L SLE L+LS N+L TVP +P L I+ L N + Q+ L L +L Sbjct: 257 LDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYL 316 Query: 197 YLHNNKF--TFIPDQSFDQLFQLQEITLYNN 225 L +N+ + +P + L L + LY N Sbjct: 317 LLQHNQLGSSGLPAGALRPLRGLHTLHLYGN 347 Score = 63.2 bits (152), Expect = 5e-10 Identities = 54/192 (28%), Positives = 90/192 (46%), Gaps = 11/192 (5%) Query: 46 LSTLPSGL---QENIIHLNLSYNHFTDLHNQLTQYTNLRTL---DISNNRLESLPAHLPR 99 +S +P G Q + L L +N TD T ++ L +L D+S+N+L ++PA LPR Sbjct: 228 ISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGLPR 287 Query: 100 SLWNMSAANNNIKLLDKSDTAYQWNLKYLDVSKNMLEKVVL---IKNTLRSLEVLNLSSN 156 +L + N I+ ++ + L+YL + N L L LR L L+L N Sbjct: 288 TLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGN 347 Query: 157 KLWTVPTNMPSKLHIVDLSNNSLTQILPGTLINLTNLTHLYLHNNKFTF--IPDQSFDQL 214 L VP +P +L + L +N + + L+ LT L L N+ + ++F +L Sbjct: 348 GLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRAFRRL 407 Query: 215 FQLQEITLYNNR 226 L+ + L N+ Sbjct: 408 RALRSLDLAGNQ 419 Score = 60.8 bits (146), Expect = 2e-09 Identities = 51/195 (26%), Positives = 81/195 (41%), Gaps = 30/195 (15%) Query: 38 HVDCSGRNLSTLPSGLQENIIHLNLSYNHFTDL-----------------HNQ------- 73 ++D S L+T+P+GL + L+L N + HNQ Sbjct: 270 YLDLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLP 329 Query: 74 ---LTQYTNLRTLDISNNRLESLPAHLPRSLWNMSAANNNIKLLDKSDTAYQWNLKYLDV 130 L L TL + N L+ +P LPR L + +N++ L D L L++ Sbjct: 330 AGALRPLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNL 389 Query: 131 SKNMLEKVVLIKNT---LRSLEVLNLSSNKLWTVPTNMPSKLHIVDLSNNSLTQILPGTL 187 + N L + LR+L L+L+ N+L +P +P+ L + L N L + P L Sbjct: 390 AYNRLASARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPL 449 Query: 188 INLTNLTHLYLHNNK 202 L L L L +N+ Sbjct: 450 AGLDQLRELSLAHNR 464 Score = 48.5 bits (114), Expect = 1e-05 Identities = 39/136 (28%), Positives = 57/136 (41%), Gaps = 8/136 (5%) Query: 36 HRHVDCSGRNLSTLPSGLQENIIHLNLSYNHFTDL---HNQLTQYTNLRTLDISNNRLES 92 H HV G GL E LNL+YN H + LR+LD++ N+L Sbjct: 367 HNHVAALGARDLVATPGLTE----LNLAYNRLASARVHHRAFRRLRALRSLDLAGNQLTR 422 Query: 93 LPAHLPRSLWNMSAANNNIKLLDKSDTAYQWNLKYLDVSKNMLEKVVLIKNTLRSLEVLN 152 LP LP L + N +++L+ A L+ L ++ N L + T L+ L Sbjct: 423 LPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLRELSLAHNRLRVGDIGPGTWHELQALQ 482 Query: 153 LSSNKL-WTVPTNMPS 167 + + TVP PS Sbjct: 483 VRHRLVSHTVPRAPPS 498 Score = 41.6 bits (96), Expect = 0.001 Identities = 27/104 (25%), Positives = 50/104 (48%), Gaps = 2/104 (1%) Query: 127 YLDVSKNMLEKVVLIKNTLRSLEVLNLSSNKLWTVPTNMPSKLHIVDLSNNSLTQILPGT 186 +L S L + ++ + ++ ++ L P N+ + L NN L ++ Sbjct: 34 HLGESLQPLPRACPLRCSCPRVDTVDCDGLDLRVFPDNITRAAQHLSLQNNQLQELPYNE 93 Query: 187 LINLTNLTHLYLHNNKFTF--IPDQSFDQLFQLQEITLYNNRWS 228 L L+ L L LHNN + +PD++F+ L QLQ + + +N+ S Sbjct: 94 LSRLSGLRTLNLHNNLISSEGLPDEAFESLTQLQHLCVAHNKLS 137 >gi|7019381 fibronectin leucine rich transmembrane protein 2 [Homo sapiens] Length = 660 Score = 79.3 bits (194), Expect = 6e-15 Identities = 62/230 (26%), Positives = 108/230 (46%), Gaps = 9/230 (3%) Query: 6 LKMSLCLFILLFLTPGILCICPLQCICTERHRHVDCSGRNLSTLPSGLQENIIHLNLSYN 65 LK L + + L+ L CP C C V C+ R+L+++P G+ E + L L N Sbjct: 16 LKSWLIISLGLYSQVSKLLACPSVCRCDRNF--VYCNERSLTSVPLGIPEGVTVLYLHNN 73 Query: 66 HFTD--LHNQLTQYTNLRTLDISNNRLESLPAHLPRSLWNMSAANNNIKLLDKSDTAYQW 123 + +L ++ T+ + N+L+ P +LP+++ + NNI+ + ++ A Sbjct: 74 QINNAGFPAELHNVQSVHTVYLYGNQLDEFPMNLPKNVRVLHLQENNIQTISRAALAQLL 133 Query: 124 NLKYLDVSKNMLEKVVLIKNTLR---SLEVLNLSSNKLWTVPTNMPSKLHIVDLSNNSLT 180 L+ L + N + V + R SL++L LS N L +VP +P L + + N + Sbjct: 134 KLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGLPVDLQELRVDENRIA 193 Query: 181 QILPGTLINLTNLTHLYLHNNKFT--FIPDQSFDQLFQLQEITLYNNRWS 228 I NLT+L L + N T I + +F L +L+E ++ N S Sbjct: 194 VISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRNSLS 243 Score = 69.3 bits (168), Expect = 6e-12 Identities = 80/319 (25%), Positives = 131/319 (41%), Gaps = 39/319 (12%) Query: 79 NLRTLDISNNRLESLPAHLPRSLWNMSAANNNIKLLDKSDTAYQ--WNLKYLDVSKNMLE 136 +L+ L +S N L S+P LP L + N I ++ SD A+Q +L+ L V N+L Sbjct: 160 SLKLLFLSKNHLSSVPVGLPVDLQELRVDENRIAVI--SDMAFQNLTSLERLIVDGNLLT 217 Query: 137 KVVLIKNT---LRSLEVLNLSSNKLWTVPTNMPSKLHIVDL--SNNSLTQILPGTLINLT 191 + + T L L+ ++ N L P ++P H++ L +N + I NL Sbjct: 218 NKGIAEGTFSHLTKLKEFSIVRNSLSHPPPDLPGT-HLIRLYLQDNQINHIPLTAFSNLR 276 Query: 192 NLTHLYLHNNKFTFIPDQSFDQLFQLQEITLYNNRWSCDHKQNITYLLKWM------MET 245 L L + NN+ + FD L L+++T NN W CD +I ++ +W+ + Sbjct: 277 KLERLDISNNQLRMLTQGVFDNLSNLKQLTARNNPWFCD--CSIKWVTEWLKYIPSSLNV 334 Query: 246 KAHVIGTPCSTQISSLKEHNMYPTPSGFTSSLFTVSGMQT-VDTINSLSVVTQPKVTKIP 304 + + P + +++E NM S T G+ ++ S TQP IP Sbjct: 335 RGFMCQGPEQVRGMAVRELNM-----NLLSCPTTTPGLPLFTPAPSTASPTTQPPTLSIP 389 Query: 305 KQYRTKETTFGATLSKDTTFTSTDKAFVPYPEDTSTETINSHEAAAATLTIHLQDGMVTN 364 R+ T T T P+ E + + L+IH V + Sbjct: 390 NPSRSY-----------TPPTPTTSKLPTIPDWDGRERVTPPISERIQLSIH----FVND 434 Query: 365 TSLTSSTKSSPTPMTLSIT 383 TS+ S S T M +T Sbjct: 435 TSIQVSWLSLFTVMAYKLT 453 >gi|205277468 leucine rich repeat containing 15 isoform a [Homo sapiens] Length = 587 Score = 77.8 bits (190), Expect = 2e-14 Identities = 71/256 (27%), Positives = 113/256 (44%), Gaps = 57/256 (22%) Query: 26 CPLQCICTERHRHVDCSGRNLSTLPSGLQENIIHLNLSYNHFTDLH-------------- 71 CP +C C+ R V+C+G + +P+ L N + L + H T+L+ Sbjct: 31 CPSECTCS-RASQVECTGARIVAVPTPLPWNAMSLQILNTHITELNESPFLNISALIALR 89 Query: 72 ---NQLTQYT--------NLRTLDISNNRLESLPAHLPR---SLWNMSAANNNIKLLDKS 117 N+L++ T +LR L ++NN+L+ LP L + SL ++ ++N + + + Sbjct: 90 IEKNELSRITPGAFRNLGSLRYLSLANNKLQVLPIGLFQGLDSLESLLLSSNQLLQIQPA 149 Query: 118 DTAYQWNLKYLDVSKNMLE--------------KVVLIKNTLR-----------SLEVLN 152 + NLK L + N LE K+ L KN+L +L+VL Sbjct: 150 HFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLR 209 Query: 153 LSSNKLWTVPTNMPS---KLHIVDLSNNSLTQILPGTLINLTNLTHLYLHNNKFTFIPDQ 209 L N+L +P L + L N + + PG N NL LYL NN + +P Sbjct: 210 LYENRLTDIPMGTFDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQLPPS 269 Query: 210 SFDQLFQLQEITLYNN 225 F QL QL +TL+ N Sbjct: 270 IFMQLPQLNRLTLFGN 285 Score = 63.9 bits (154), Expect = 3e-10 Identities = 59/199 (29%), Positives = 89/199 (44%), Gaps = 16/199 (8%) Query: 56 NIIHLNLSYNHFTDLHNQL-TQYTNLRTLDISNNRLESL------PAHLPRSLWNMSAAN 108 N+ L LS NH + L + Q L L + N L+ L P R LW + Sbjct: 252 NLQRLYLSNNHISQLPPSIFMQLPQLNRLTLFGNSLKELSLGIFGPMPNLRELW---LYD 308 Query: 109 NNIKLLDKSDTAYQWNLKYLDVSKNMLEKVVL-IKNTLRSLEVLNLSSNKLWTVPTN--- 164 N+I L + + L+ L +S+N + + N L L L+L +N L + N Sbjct: 309 NHISSLPDNVFSNLRQLQVLILSRNQISFISPGAFNGLTELRELSLHTNALQDLDGNVFR 368 Query: 165 MPSKLHIVDLSNNSLTQILPGTLINLTNLTHLYLHNNKFTFIPDQSFDQLFQLQEITLYN 224 M + L + L NN L Q+ N+ L + L NN+ +P FD L +L E+ LY+ Sbjct: 369 MLANLQNISLQNNRLRQLPGNIFANVNGLMAIQLQNNQLENLPLGIFDHLGKLCELRLYD 428 Query: 225 NRWSCDHKQNITYLLKWMM 243 N W CD +I L W++ Sbjct: 429 NPWRCD--SDILPLRNWLL 445 >gi|18677767 leucine rich repeat containing 15 isoform b [Homo sapiens] Length = 581 Score = 77.8 bits (190), Expect = 2e-14 Identities = 71/256 (27%), Positives = 113/256 (44%), Gaps = 57/256 (22%) Query: 26 CPLQCICTERHRHVDCSGRNLSTLPSGLQENIIHLNLSYNHFTDLH-------------- 71 CP +C C+ R V+C+G + +P+ L N + L + H T+L+ Sbjct: 25 CPSECTCS-RASQVECTGARIVAVPTPLPWNAMSLQILNTHITELNESPFLNISALIALR 83 Query: 72 ---NQLTQYT--------NLRTLDISNNRLESLPAHLPR---SLWNMSAANNNIKLLDKS 117 N+L++ T +LR L ++NN+L+ LP L + SL ++ ++N + + + Sbjct: 84 IEKNELSRITPGAFRNLGSLRYLSLANNKLQVLPIGLFQGLDSLESLLLSSNQLLQIQPA 143 Query: 118 DTAYQWNLKYLDVSKNMLE--------------KVVLIKNTLR-----------SLEVLN 152 + NLK L + N LE K+ L KN+L +L+VL Sbjct: 144 HFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLR 203 Query: 153 LSSNKLWTVPTNMPS---KLHIVDLSNNSLTQILPGTLINLTNLTHLYLHNNKFTFIPDQ 209 L N+L +P L + L N + + PG N NL LYL NN + +P Sbjct: 204 LYENRLTDIPMGTFDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQLPPS 263 Query: 210 SFDQLFQLQEITLYNN 225 F QL QL +TL+ N Sbjct: 264 IFMQLPQLNRLTLFGN 279 Score = 63.9 bits (154), Expect = 3e-10 Identities = 59/199 (29%), Positives = 89/199 (44%), Gaps = 16/199 (8%) Query: 56 NIIHLNLSYNHFTDLHNQL-TQYTNLRTLDISNNRLESL------PAHLPRSLWNMSAAN 108 N+ L LS NH + L + Q L L + N L+ L P R LW + Sbjct: 246 NLQRLYLSNNHISQLPPSIFMQLPQLNRLTLFGNSLKELSLGIFGPMPNLRELW---LYD 302 Query: 109 NNIKLLDKSDTAYQWNLKYLDVSKNMLEKVVL-IKNTLRSLEVLNLSSNKLWTVPTN--- 164 N+I L + + L+ L +S+N + + N L L L+L +N L + N Sbjct: 303 NHISSLPDNVFSNLRQLQVLILSRNQISFISPGAFNGLTELRELSLHTNALQDLDGNVFR 362 Query: 165 MPSKLHIVDLSNNSLTQILPGTLINLTNLTHLYLHNNKFTFIPDQSFDQLFQLQEITLYN 224 M + L + L NN L Q+ N+ L + L NN+ +P FD L +L E+ LY+ Sbjct: 363 MLANLQNISLQNNRLRQLPGNIFANVNGLMAIQLQNNQLENLPLGIFDHLGKLCELRLYD 422 Query: 225 NRWSCDHKQNITYLLKWMM 243 N W CD +I L W++ Sbjct: 423 NPWRCD--SDILPLRNWLL 439 >gi|150417978 platelet glycoprotein Ib alpha polypeptide precursor [Homo sapiens] Length = 639 Score = 77.4 bits (189), Expect = 2e-14 Identities = 116/455 (25%), Positives = 174/455 (38%), Gaps = 79/455 (17%) Query: 12 LFILLFLTPGILC---ICPLQCICTERHRHVDCSGRNLSTLPSGLQEN--IIHLN----- 61 L +LL L P L IC + + + H V+C RNL+ LP L ++ I+HL+ Sbjct: 3 LLLLLLLLPSPLHPHPICEVSKVAS--HLEVNCDKRNLTALPPDLPKDTTILHLSENLLY 60 Query: 62 -------LSYNHFTDLHNQLTQYTNLR---------TLDISNNRLESLPAHLPRSLWNMS 105 + Y T L+ + T L+ TLD+S+N+L+SLP Sbjct: 61 TFSLATLMPYTRLTQLNLDRCELTKLQVDGTLPVLGTLDLSHNQLQSLP----------- 109 Query: 106 AANNNIKLLDKSDTAYQWNLKYLDVSKNMLEKVVL-IKNTLRSLEVLNLSSNKLWTVPTN 164 LL ++ A L LDVS N L + L L L+ L L N+L T+P Sbjct: 110 -------LLGQTLPA----LTVLDVSFNRLTSLPLGALRGLGELQELYLKGNELKTLPPG 158 Query: 165 M---PSKLHIVDLSNNSLTQILPGTLINLTNLTHLYLHNNKFTFIPDQSFDQLFQLQEIT 221 + KL + L+NN+LT++ G L L NL L L N IP + F L Sbjct: 159 LLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIP-KGFFGSHLLPFAF 217 Query: 222 LYNNRWSCDHKQNITYLLKWMMETKAHV------------IGTPCSTQISSLKEHNMYPT 269 L+ N W C+ + I Y +W+ + +V S Q + + +Y Sbjct: 218 LHGNPWLCNCE--ILYFRRWLQDNAENVYVWKQGVDVKAMTSNVASVQCDNSDKFPVYKY 275 Query: 270 PSGFTSSLFTVSGMQTVD-----TINSLSVVTQPKVTKIPKQYRTKETTFGATLSKDTTF 324 P +L D V V K P + T T +G S T Sbjct: 276 PGKGCPTLGDEGDTDLYDYYPEEDTEGDKVRATRTVVKFPTKAHT--TPWGLFYSWSTAS 333 Query: 325 TSTDKAFVPYPEDTST-ETINSHEAAAATLTIHLQDGMVTNTSLTSSTKSSPTPMTLS-I 382 + +P ST E T+H++ + T S+T+ +P+P T + Sbjct: 334 LDSQMPSSLHPTQESTKEQTTFPPRWTPNFTLHMESITFSKTP-KSTTEPTPSPTTSEPV 392 Query: 383 TSGMPNNFSEMPQQSTTLNLWREETTTNVKTPLPS 417 PN + P S T E + TP P+ Sbjct: 393 PEPAPNMTTLEPTPSPTTPEPTSEPAPSPTTPEPT 427 >gi|34577057 fibronectin leucine rich transmembrane protein 1 [Homo sapiens] Length = 674 Score = 77.4 bits (189), Expect = 2e-14 Identities = 59/224 (26%), Positives = 107/224 (47%), Gaps = 10/224 (4%) Query: 10 LCLFILLFLTPGI-LCICPLQCICTERHRHVDCSGRNLSTLPSGLQENIIHLNLSYNHFT 68 LC ++ FLT I CP C C + + C+ R L+++P+ + ++ L L N Sbjct: 37 LCYGLIAFLTEVIDSTTCPSVCRCD--NGFIYCNDRGLTSIPADIPDDATTLYLQNNQIN 94 Query: 69 D--LHNQLTQYTNLRTLDISNNRLESLPAHLPRSLWNMSAANNNIKLLDKSDTAYQWNLK 126 + + L N++ + + N L+ P +LPRSL + +NN++ + + A L+ Sbjct: 95 NAGIPQDLKTKVNVQVIYLYENDLDEFPINLPRSLRELHLQDNNVRTIARDSLARIPLLE 154 Query: 127 YLDVSKNMLEKVVLIKNTL---RSLEVLNLSSNKLWTVPTNMPSKLHIVDLSNNSLTQIL 183 L + N + V + ++ + L++L LS N L ++P+ +P L + L +N ++ I Sbjct: 155 KLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLPHTLEELRLDDNRISTIP 214 Query: 184 PGTLINLTNLTHLYLHNNKFT--FIPDQSFDQLFQLQEITLYNN 225 L +L L L N I D +F +L L E++L N Sbjct: 215 LHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRN 258 Score = 71.2 bits (173), Expect = 2e-12 Identities = 54/174 (31%), Positives = 84/174 (48%), Gaps = 6/174 (3%) Query: 80 LRTLDISNNRLESLPAHLPRSLWNMSAANNNIKLLDKSDTAYQWNLKYLDVSKNMLEKVV 139 L+ L +S N L S+P+ LP +L + +N I + +L+ L + N+L Sbjct: 179 LKLLFLSRNHLSSIPSGLPHTLEELRLDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQR 238 Query: 140 LIKNT---LRSLEVLNLSSNKLWTVPTNMPSK-LHIVDLSNNSLTQILPGTLINLTNLTH 195 + +T L++L L+L N L P N+PS L + L +N+++ I TL + L Sbjct: 239 IADDTFSRLQNLTELSLVRNSLAAPPLNLPSAHLQKLYLQDNAISHIPYNTLAKMRELER 298 Query: 196 LYLHNNKFTFIPDQSFDQLFQLQEITLYNNRWSCDHKQNITYLLKWMMETKAHV 249 L L NN T +P FD L L ++ L NN W C N+ +L W+ A V Sbjct: 299 LDLSNNNLTTLPRGLFDDLGNLAQLLLRNNPWFCG--CNLMWLRDWVKARAAVV 350 Score = 28.9 bits (63), Expect = 9.7 Identities = 18/57 (31%), Positives = 29/57 (50%), Gaps = 2/57 (3%) Query: 49 LPSGLQENIIHLNLSYNHFTDLHNQLTQYTNLRTLDISNNRLESLPAHLPRSLWNMS 105 LPS + + + + +H +N L + L LD+SNN L +LP L L N++ Sbjct: 267 LPSAHLQKLYLQDNAISHIP--YNTLAKMRELERLDLSNNNLTTLPRGLFDDLGNLA 321 >gi|238908508 leucine-rich repeat and death domain-containing protein [Homo sapiens] Length = 860 Score = 77.0 bits (188), Expect = 3e-14 Identities = 60/185 (32%), Positives = 94/185 (50%), Gaps = 28/185 (15%) Query: 46 LSTLPSGLQ--ENIIHLNLSYNHFTDLHNQLTQYTNLRTLDISNNRLESLPAHLPRSLWN 103 LS+LPS +Q N+ LN+S+NH + + +++Q N+R L NN +E+ P Sbjct: 200 LSSLPSEIQLLHNLRILNVSHNHISHIPKEISQLGNIRQLFFYNNYIENFP--------- 250 Query: 104 MSAANNNIKLLDKSDTAYQWNLKYLDVSKNMLEKVVLIKNTLRSLEVLNLSSNKLWTVPT 163 SD NL+ L + KN L + +L++L VLNL N+L T P Sbjct: 251 -------------SDLECLGNLEILSLGKNKLRHIPDTLPSLKTLRVLNLEYNQLTTFPK 297 Query: 164 NM--PSKLHIVDLSNNSLTQILPGTLINLTNLTHLYLHNNKFTFIPDQSFDQLFQLQEIT 221 + KL +DL+ N L LP + L NL L + +NK TF+ + F QL +++E+ Sbjct: 298 ALCFLPKLISLDLTGN-LISSLPKEIRELKNLETLLMDHNKLTFLAVEIF-QLLKIKELQ 355 Query: 222 LYNNR 226 L +N+ Sbjct: 356 LADNK 360 Score = 73.6 bits (179), Expect = 3e-13 Identities = 60/214 (28%), Positives = 103/214 (48%), Gaps = 18/214 (8%) Query: 27 PLQCICTERHRHVDCSGRNLSTLPSGLQ--ENIIHLNLSYNHFTDLHNQLTQYTNLRTLD 84 PL + ++ +G +S +P + + ++HL LS N NL+ LD Sbjct: 480 PLGLCALDSLYYLSVNGNYISEIPVDISFSKQLLHLELSENKLLIFSEHFCSLINLKYLD 539 Query: 85 ISNNRLESLPAHLPRSLWNMSAANNNIKLLDKSDTAYQW-----NLKYLDVSKNMLEKVV 139 + N+++ +PA S+ NM + + I +K +T + NL+ LD+S+N L+K+ Sbjct: 540 LGKNQIKKIPA----SISNMISLHVLILCCNKFETFPRELCTLENLQVLDLSENQLQKIS 595 Query: 140 LIKNTLRSLEVLNLSSNKLWTVPTNMPS-----KLHIVDLSNNSLTQILPGTLINLTNLT 194 L+ ++ LN SSN+ P + +L+I + LT+ LPG L N+T L Sbjct: 596 SDICNLKGIQKLNFSSNQFIHFPIELCQLQSLEQLNISQIKGRKLTR-LPGELSNMTQLK 654 Query: 195 HLYLHNNKFTFIPDQSFDQLFQLQEITLYNNRWS 228 L + NN IP ++ +L L + YNN+ S Sbjct: 655 ELDISNNAIREIP-RNIGELRNLVSLHAYNNQIS 687 Score = 67.4 bits (163), Expect = 2e-11 Identities = 57/207 (27%), Positives = 98/207 (47%), Gaps = 17/207 (8%) Query: 24 CICPLQCICTERHRHVDCSGRNLSTLPSGLQ--ENIIHLNLSYNHFTDLHNQLTQYTNLR 81 CI L IC+ ++ SG ++ +P ++ + II + LSYN L +L Sbjct: 436 CISHLNNICS-----LEFSGNIITDVPIEIKNCQKIIKIELSYNKIMYFPLGLCALDSLY 490 Query: 82 TLDISNNRLESLPAHLP--RSLWNMSAANNNIKLLDKSDTAYQWNLKYLDVSKNMLEKVV 139 L ++ N + +P + + L ++ + N + + + + NLKYLD+ KN ++K+ Sbjct: 491 YLSVNGNYISEIPVDISFSKQLLHLELSENKLLIFSEHFCSLI-NLKYLDLGKNQIKKIP 549 Query: 140 LIKNTLRSLEVLNLSSNKLWTVPTNMPS--KLHIVDLSNNSLTQILPGTLINLTNLTHLY 197 + + SL VL L NK T P + + L ++DLS N L Q + + NL + L Sbjct: 550 ASISNMISLHVLILCCNKFETFPRELCTLENLQVLDLSENQL-QKISSDICNLKGIQKLN 608 Query: 198 LHNNKFTFIPDQSFDQLFQLQEITLYN 224 +N+F P +L QLQ + N Sbjct: 609 FSSNQFIHFP----IELCQLQSLEQLN 631 Score = 48.5 bits (114), Expect = 1e-05 Identities = 45/171 (26%), Positives = 83/171 (48%), Gaps = 14/171 (8%) Query: 46 LSTLPSGL--QENIIHLNLSYNHFTDLHNQLTQYTNLRTLDISNNRLESLPAHLPRSLW- 102 L+T P L +I L+L+ N + L ++ + NL TL + +N+L L + + L Sbjct: 292 LTTFPKALCFLPKLISLDLTGNLISSLPKEIRELKNLETLLMDHNKLTFLAVEIFQLLKI 351 Query: 103 -NMSAANNNIKLLDKSDTAYQWNLKYLDVSKNMLEKVVLIKNTLRSLEVLNLSSNKLWTV 161 + A+N ++++ ++ L+ L + KN+L+ + + LE L+LS NKL + Sbjct: 352 KELQLADNKLEVISHKIENFR-ELRILILDKNLLKNIPEKISCCAMLECLSLSDNKLTEL 410 Query: 162 P-----TNMPSKLHIVDLSNNSLTQILPGTLINLTNLTHLYLHNNKFTFIP 207 P N KLH+ + N++ +I + +L N+ L N T +P Sbjct: 411 PKYIHKLNNLRKLHV---NRNNMVKI-TDCISHLNNICSLEFSGNIITDVP 457 Score = 43.5 bits (101), Expect = 4e-04 Identities = 34/116 (29%), Positives = 58/116 (50%), Gaps = 6/116 (5%) Query: 55 ENIIHLNLSY---NHFTDLHNQLTQYTNLRTLDISNNRLESLPAHLP--RSLWNMSAANN 109 +++ LN+S T L +L+ T L+ LDISNN + +P ++ R+L ++ A NN Sbjct: 625 QSLEQLNISQIKGRKLTRLPGELSNMTQLKELDISNNAIREIPRNIGELRNLVSLHAYNN 684 Query: 110 NIKLLDKSDTAYQWNLKYLDVSKNMLEKVVLIKNTLRSLEVLNLSSNKLWTVPTNM 165 I L S + +L+ L++S N L + + SL+ +N N L P + Sbjct: 685 QISYLPPSLLSLN-DLQQLNLSGNNLTALPSAIYNIFSLKEINFDDNPLLRPPVEI 739 Score = 29.3 bits (64), Expect = 7.4 Identities = 16/61 (26%), Positives = 31/61 (50%), Gaps = 2/61 (3%) Query: 37 RHVDCSGRNLSTLPSGLQE--NIIHLNLSYNHFTDLHNQLTQYTNLRTLDISNNRLESLP 94 + +D S + +P + E N++ L+ N + L L +L+ L++S N L +LP Sbjct: 654 KELDISNNAIREIPRNIGELRNLVSLHAYNNQISYLPPSLLSLNDLQQLNLSGNNLTALP 713 Query: 95 A 95 + Sbjct: 714 S 714 >gi|156139147 leucine rich repeat transmembrane neuronal 4 isoform b [Homo sapiens] Length = 518 Score = 77.0 bits (188), Expect = 3e-14 Identities = 85/319 (26%), Positives = 139/319 (43%), Gaps = 25/319 (7%) Query: 56 NIIHLNLSYNHFTDLHNQLTQYTNLRTLDI---SNNRLESLPAHLPRSLWNMSAAN---N 109 N+ +L+LSYN L ++ Q+ LR L I +N L+++P + + N+ + N Sbjct: 134 NLRNLDLSYNKLQTLQSE--QFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYN 191 Query: 110 NIKLLDKSDTAYQWNLKYLDVSKNMLEKVVLIK-NTLRSLEVLNLSSNKLWTVPTNMP-- 166 ++ L ++ A LK L + N K+ L +L + L N++ ++ + Sbjct: 192 RLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWT 251 Query: 167 -SKLHIVDLSNNSLTQILPGTLINLTNLTHLYLHNNKFTFIPDQSFDQLFQLQEITLYNN 225 S LH +DLS N + I PGT L NL L L +NK T I ++ + L ITL N Sbjct: 252 WSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSGN 311 Query: 226 RWSCDHKQNITYLLKWMMETKAHVIGTPCSTQISSLKEHNMYPTPSGFTSSLFTVSGMQT 285 W C ++I L W+ K G ST I + +H S + S +Q Sbjct: 312 MWEC--SRSICPLFYWLKNFK----GNKESTMICAGPKHIQGEKVSDAVETYNICSEVQV 365 Query: 286 VDTINSLSVVTQP-KVTKIPKQYRTKETTFGATLSKDTTFTSTDKAFVPYP-EDTSTETI 343 V+T S V P K IP + T F +++ T T + P + E + Sbjct: 366 VNTERSHLVPQTPQKPLIIP-----RPTIFKPDVTQSTFETPSPSPGFQIPGAEQEYEHV 420 Query: 344 NSHEAAAATLTIHLQDGMV 362 + H+ A ++ + L M+ Sbjct: 421 SFHKIIAGSVALFLSVAMI 439 Score = 33.5 bits (75), Expect = 0.39 Identities = 20/92 (21%), Positives = 43/92 (46%) Query: 142 KNTLRSLEVLNLSSNKLWTVPTNMPSKLHIVDLSNNSLTQILPGTLINLTNLTHLYLHNN 201 KN +++ S+ +P N+ + L NS+ ++ L L LYL +N Sbjct: 36 KNCRCDGKIVYCESHAFADIPENISGGSQGLSLRFNSIQKLKSNQFAGLNQLIWLYLDHN 95 Query: 202 KFTFIPDQSFDQLFQLQEITLYNNRWSCDHKQ 233 + + + +F + +L+E+ L +N+ + H + Sbjct: 96 YISSVDEDAFQGIRRLKELILSSNKITYLHNK 127 >gi|197927168 leucine rich repeat transmembrane neuronal 4 isoform a [Homo sapiens] Length = 590 Score = 77.0 bits (188), Expect = 3e-14 Identities = 85/319 (26%), Positives = 139/319 (43%), Gaps = 25/319 (7%) Query: 56 NIIHLNLSYNHFTDLHNQLTQYTNLRTLDI---SNNRLESLPAHLPRSLWNMSAAN---N 109 N+ +L+LSYN L ++ Q+ LR L I +N L+++P + + N+ + N Sbjct: 134 NLRNLDLSYNKLQTLQSE--QFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYN 191 Query: 110 NIKLLDKSDTAYQWNLKYLDVSKNMLEKVVLIK-NTLRSLEVLNLSSNKLWTVPTNMP-- 166 ++ L ++ A LK L + N K+ L +L + L N++ ++ + Sbjct: 192 RLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWT 251 Query: 167 -SKLHIVDLSNNSLTQILPGTLINLTNLTHLYLHNNKFTFIPDQSFDQLFQLQEITLYNN 225 S LH +DLS N + I PGT L NL L L +NK T I ++ + L ITL N Sbjct: 252 WSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSGN 311 Query: 226 RWSCDHKQNITYLLKWMMETKAHVIGTPCSTQISSLKEHNMYPTPSGFTSSLFTVSGMQT 285 W C ++I L W+ K G ST I + +H S + S +Q Sbjct: 312 MWEC--SRSICPLFYWLKNFK----GNKESTMICAGPKHIQGEKVSDAVETYNICSEVQV 365 Query: 286 VDTINSLSVVTQP-KVTKIPKQYRTKETTFGATLSKDTTFTSTDKAFVPYP-EDTSTETI 343 V+T S V P K IP + T F +++ T T + P + E + Sbjct: 366 VNTERSHLVPQTPQKPLIIP-----RPTIFKPDVTQSTFETPSPSPGFQIPGAEQEYEHV 420 Query: 344 NSHEAAAATLTIHLQDGMV 362 + H+ A ++ + L M+ Sbjct: 421 SFHKIIAGSVALFLSVAMI 439 Score = 33.5 bits (75), Expect = 0.39 Identities = 20/92 (21%), Positives = 43/92 (46%) Query: 142 KNTLRSLEVLNLSSNKLWTVPTNMPSKLHIVDLSNNSLTQILPGTLINLTNLTHLYLHNN 201 KN +++ S+ +P N+ + L NS+ ++ L L LYL +N Sbjct: 36 KNCRCDGKIVYCESHAFADIPENISGGSQGLSLRFNSIQKLKSNQFAGLNQLIWLYLDHN 95 Query: 202 KFTFIPDQSFDQLFQLQEITLYNNRWSCDHKQ 233 + + + +F + +L+E+ L +N+ + H + Sbjct: 96 YISSVDEDAFQGIRRLKELILSSNKITYLHNK 127 >gi|7662102 leucine rich repeat transmembrane neuronal 2 [Homo sapiens] Length = 516 Score = 75.9 bits (185), Expect = 7e-14 Identities = 63/240 (26%), Positives = 112/240 (46%), Gaps = 15/240 (6%) Query: 14 ILLFLTPGILCICPLQCICTERHRHVDCSGRNLSTLPSGLQENIIHLNLSYNHFTDL-HN 72 ++L + P + CP +C C + + D G ++P+ + + L+L +NH T+L + Sbjct: 22 MVLKMLPALGMACPPKCRCEKLLFYCDSQG--FHSVPNATDKGSLGLSLRHNHITELERD 79 Query: 73 QLTQYTNLRTLDISNNRLESLPAHLPRSLWNMS---AANNNIKLLDKSDTAYQWNLKYLD 129 Q ++ L L + +N++ ++ + L+ + ++N I L + NL+ LD Sbjct: 80 QFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLPNTTFTQLINLQNLD 139 Query: 130 VSKNMLEKV-VLIKNTLRSLEVLNLSSNKLWTVPTNM---PSKLHIVDLSNNSLTQILPG 185 +S N L + + LR L+ L+L SN L T+P + L +DLS N L + Sbjct: 140 LSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARN 199 Query: 186 TLINLTNLTHLYLHNNKFTFIPDQSFDQLFQLQEITLYNNRWSCDHKQNITYLLKWMMET 245 L L L+L +N+ T I F +L L + L N+ S N+T ++W T Sbjct: 200 GFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKIS-----NLTCGMEWTWGT 254 Score = 62.4 bits (150), Expect = 8e-10 Identities = 54/195 (27%), Positives = 87/195 (44%), Gaps = 10/195 (5%) Query: 56 NIIHLNLSYNHFTDLHNQLTQ-YTNLRTLDISNNRLESLPAHL---PRSLWNMSAANNNI 111 N+ +L+LS+N + LH +L L+TL + +N L ++P L RSL + + N + Sbjct: 134 NLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRL 193 Query: 112 KLLDKSDTAYQWNLKYLDVSKNMLEKVVLIKNT-LRSLEVLNLSSNKLWTVPTNMP---S 167 + L ++ A L+ L + N L K+ L SL L L NK+ + M Sbjct: 194 RSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTCGMEWTWG 253 Query: 168 KLHIVDLSNNSLTQILPGTLINLTNLTHLYLHNNKFTFIPDQSFDQLFQLQEITLYNNRW 227 L +DL+ N + I + NL L + NNK + + + L L + L N W Sbjct: 254 TLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLRSLTTVGLSGNLW 313 Query: 228 SCDHKQNITYLLKWM 242 C + I L W+ Sbjct: 314 ECSAR--ICALASWL 326 >gi|109809759 leucine rich repeat transmembrane neuronal 3 [Homo sapiens] Length = 581 Score = 75.1 bits (183), Expect = 1e-13 Identities = 84/314 (26%), Positives = 131/314 (41%), Gaps = 30/314 (9%) Query: 56 NIIHLNLSYNHFTDLHNQLTQYTNLR---TLDISNNRLESLPAHLPRSLWNMSAAN---N 109 N+ +L+LSYN L ++ Q+ LR +L + +N L ++P + + N+ + N Sbjct: 134 NLRNLDLSYNQLHSLGSE--QFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYN 191 Query: 110 NIKLLDKSDTAYQWNLKYLDVSKNMLEKVVL-IKNTLRSLEVLNLSSNKLWTVPTNMP-- 166 I+ L ++ A LK L + N K+ L + L SL+ L L NK+ + M Sbjct: 192 RIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSWT 251 Query: 167 -SKLHIVDLSNNSLTQIL-PGTLINLTNLTHLYLHNNKFTFIPDQSFDQLFQLQEITLYN 224 S L +DLS N + P + NL L L +NK TFI + D L +I+L Sbjct: 252 WSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEILDSWISLNDISLAG 311 Query: 225 NRWSCDHKQNITYLLKWMMETKAHVIGTPCSTQISSLKEHNMYPTPSGFTSSLFTVSGMQ 284 N W C +NI L+ W+ K T L+ N+ +++ G Sbjct: 312 NIWEC--SRNICSLVNWLKSFKGLRENTIICASPKELQGVNVIDAVKN-----YSICGKS 364 Query: 285 TVDTINSLSVVTQPKVTKIPKQYRTKETTFGATLSKDTTFTSTDKAFVPYPE-DTSTETI 343 T + + + PK T PK R K T A P PE D E I Sbjct: 365 TTERFDLARAL--PKPTFKPKLPRPKH-------ESKPPLPPTVGATEPGPETDADAEHI 415 Query: 344 NSHEAAAATLTIHL 357 + H+ A ++ + L Sbjct: 416 SFHKIIAGSVALFL 429 Score = 38.5 bits (88), Expect = 0.012 Identities = 23/74 (31%), Positives = 41/74 (55%) Query: 155 SNKLWTVPTNMPSKLHIVDLSNNSLTQILPGTLINLTNLTHLYLHNNKFTFIPDQSFDQL 214 S KL +P+++ + + L NSL ++ L LT LYL +N + I + +F+ + Sbjct: 49 SQKLQEIPSSISAGCLGLSLRYNSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGI 108 Query: 215 FQLQEITLYNNRWS 228 +L+E+ L +NR S Sbjct: 109 RRLKELILSSNRIS 122 >gi|198041768 synleurin [Homo sapiens] Length = 622 Score = 74.3 bits (181), Expect = 2e-13 Identities = 67/221 (30%), Positives = 110/221 (49%), Gaps = 10/221 (4%) Query: 13 FILLFLTPGILCICPLQCICTERHRHVDCSGRNLSTLPSGLQENIIHLNLSYNHFTDLH- 71 ++LL L IL + +CT R ++C LS++P E+ + L L+ N+ + ++ Sbjct: 20 YLLLLLHKEILGCSSVCQLCTGRQ--INCRNLGLSSIPKNFPESTVFLYLTGNNISYINE 77 Query: 72 NQLTQYTNLRTLDISN-NRLESLPAHLP--RSLWNMSAANNNIKLLDKSDTAYQWNLKYL 128 ++LT +L L + N N L P R L+ + NN IK LD NL+ L Sbjct: 78 SELTGLHSLVALYLDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRLDPGIFKGLLNLRNL 137 Query: 129 DVSKNMLEKVVL-IKNTLRSLEVLNLSSNKLWTVPTNM---PSKLHIVDLSNNSLTQILP 184 + N + V + N L S++ LNL N+L + + L I+DLSNN++ +I Sbjct: 138 YLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRILDLSNNNILRISE 197 Query: 185 GTLINLTNLTHLYLHNNKFTFIPDQSFDQLFQLQEITLYNN 225 +L NL LYL +N T +P +F+ L L+ ++L +N Sbjct: 198 SGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHN 238 Score = 55.8 bits (133), Expect = 7e-08 Identities = 53/177 (29%), Positives = 91/177 (51%), Gaps = 12/177 (6%) Query: 37 RHVDCSGRNLSTLP-SGLQ--ENIIHLNLSYNHFTDL-HNQLTQYTNLRTLDISNNRLES 92 R +D S N+ + SG Q EN+ L L N+ T + N +LR L +S+N +E+ Sbjct: 183 RILDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEA 242 Query: 93 LPAHLPRSLWNMS---AANNNIKLLDKSDTAYQWNLKYLDVSKNMLEKVVLIK-NTLRSL 148 + + L N+ N+ I+ + + + NLK+L +S N LE + + L++L Sbjct: 243 IQPFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKNL 302 Query: 149 EVLNLSSNKLWTVPT----NMPSKLHIVDLSNNSLTQILPGTLINLTNLTHLYLHNN 201 L L N++ ++ NM + L I++LS N+LT + P L L++L HL ++N Sbjct: 303 IYLKLDRNRIISIDNDTFENMGASLKILNLSFNNLTALHPRVLKPLSSLIHLQANSN 359 Score = 51.2 bits (121), Expect = 2e-06 Identities = 41/149 (27%), Positives = 65/149 (43%), Gaps = 26/149 (17%) Query: 81 RTLDISNNRLESLPAHLPRSLWNMSAANNNIKLLDKSDTAYQWNLKYLDVSKNMLEKVVL 140 R ++ N L S+P + P S + NNI +++S+ Sbjct: 42 RQINCRNLGLSSIPKNFPESTVFLYLTGNNISYINESELT-------------------- 81 Query: 141 IKNTLRSLEVLNL-SSNKLWTVPTNMPSKLHI--VDLSNNSLTQILPGTLINLTNLTHLY 197 L SL L L +SN L+ P H+ + L+NN + ++ PG L NL +LY Sbjct: 82 ---GLHSLVALYLDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRLDPGIFKGLLNLRNLY 138 Query: 198 LHNNKFTFIPDQSFDQLFQLQEITLYNNR 226 L N+ +F+P F+ L +Q + L NR Sbjct: 139 LQYNQVSFVPRGVFNDLVSVQYLNLQRNR 167 Score = 40.4 bits (93), Expect = 0.003 Identities = 45/179 (25%), Positives = 76/179 (42%), Gaps = 8/179 (4%) Query: 56 NIIHLNLSYNHFTDL-HNQLTQYTNLRTLDISNNRLESLPAHL---PRSLWNMSAANNNI 111 N+ +L L YN + + +++ L++ NRL L + +L + +NNNI Sbjct: 133 NLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRILDLSNNNI 192 Query: 112 KLLDKSDTAYQWNLKYLDVSKNMLEKVVLIK-NTLRSLEVLNLSSNKLWTVPT---NMPS 167 + +S + NL L + N L KV L+SL L+LS N + + + Sbjct: 193 LRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQPFAFKGLA 252 Query: 168 KLHIVDLSNNSLTQILPGTLINLTNLTHLYLHNNKFTFIPDQSFDQLFQLQEITLYNNR 226 L + L N+ + + + NL HL L +N + +F L L + L NR Sbjct: 253 NLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKNLIYLKLDRNR 311 Score = 31.2 bits (69), Expect = 2.0 Identities = 26/105 (24%), Positives = 46/105 (43%), Gaps = 7/105 (6%) Query: 124 NLKYLDVSKNMLEKVVLIKNTLRSLEVLNLSSNKLWTVPTNMPSKLHIVDLSNNSLTQIL 183 NL + KN E V + T ++ +N S T + S + + L N+++ + Sbjct: 48 NLGLSSIPKNFPESTVFLYLTGNNISYINESEL------TGLHSLVALY-LDNSNILYVY 100 Query: 184 PGTLINLTNLTHLYLHNNKFTFIPDQSFDQLFQLQEITLYNNRWS 228 P + L +L L+L+NN + F L L+ + L N+ S Sbjct: 101 PKAFVQLRHLYFLFLNNNFIKRLDPGIFKGLLNLRNLYLQYNQVS 145 >gi|4504379 leucine-rich repeat-containing G protein-coupled receptor 5 [Homo sapiens] Length = 907 Score = 73.2 bits (178), Expect = 4e-13 Identities = 76/243 (31%), Positives = 104/243 (42%), Gaps = 39/243 (16%) Query: 1 MEYQILKMSLCLFILLFLTPG--------ILCICPLQCICTERHR---HVDCSGRNLSTL 49 M+ L + L L +LL L G +L CP C C R VDCS LS L Sbjct: 1 MDTSRLGVLLSLPVLLQLATGGSSPRSGVLLRGCPTHCHCEPDGRMLLRVDCSDLGLSEL 60 Query: 50 PSGLQENIIHLNLSYNHFTDLHNQLTQYTNLRTLDISNNRLESLPAHLP--RSLWNMSAA 107 PS L +L+LS N+ + L LP LP R L + A Sbjct: 61 PSNLSVFTSYLDLSMNNISQL----------------------LPNPLPSLRFLEELRLA 98 Query: 108 NNNIKLLDKSDTAYQWNLKYLDVSKNMLEKV-VLIKNTLRSLEVLNLSSNKLWTVPTNMP 166 N + + K ++LK L + N L V LRSL+ L L +N + VP + Sbjct: 99 GNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCF 158 Query: 167 SKLHIVD---LSNNSLTQILPGTLINLTNLTHLYLHNNKFTFIPDQSFDQLFQLQEITLY 223 S LH + L +N+LT+I +L+ L + L NK IPD +F L L + L+ Sbjct: 159 SGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLH 218 Query: 224 NNR 226 NNR Sbjct: 219 NNR 221 Score = 48.5 bits (114), Expect = 1e-05 Identities = 51/197 (25%), Positives = 86/197 (43%), Gaps = 34/197 (17%) Query: 60 LNLSYNHFTDLHNQLTQYTNLRTLDISNNRLESLPA------------------------ 95 L+L+YN+ + + +NL+ L +N + S+P Sbjct: 239 LDLNYNNLDEFPTAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGR 298 Query: 96 ----HLP--RSLWNMSAANNNIKLLDKSDTAYQWNLKYLDVSKNMLEKVVLIKNTLRSLE 149 HLP R+L ++ A+ + D + TA +L + L + V N L +L+ Sbjct: 299 SAFQHLPELRTL-TLNGASQITEFPDLTGTANLESLTLTGAQISSLPQTVC--NQLPNLQ 355 Query: 150 VLNLSSNKLWTVPT-NMPSKLHIVDLSNNSLTQILPGTLINLTNLTHLYLHNNKFTFIPD 208 VL+LS N L +P+ ++ KL +DL +N + +I T L +L L L NK I Sbjct: 356 VLDLSYNLLEDLPSFSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHP 415 Query: 209 QSFDQLFQLQEITLYNN 225 +F L L ++ L +N Sbjct: 416 NAFSTLPSLIKLDLSSN 432 Score = 35.8 bits (81), Expect = 0.079 Identities = 38/176 (21%), Positives = 76/176 (43%), Gaps = 26/176 (14%) Query: 51 SGLQENIIHLNLSYNHFTDLHNQ-LTQYTNLRTLDISNNRLESLPAHLPRSLWNMSAA-- 107 SGL ++ HL L N T++ Q + L+ + ++ N++ +P + +L ++ Sbjct: 159 SGLH-SLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHL 217 Query: 108 -NNNIKLLDKSDTAYQWNLKYLDVSKNMLEKVVLIKNTLRSLEVLNLSSNKLWTVPTNMP 166 NN I L K +L+ LD++ N L++ TL +L+ L SN + ++P Sbjct: 218 HNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAIRTLSNLKELGFHSNNIRSIPEK-- 275 Query: 167 SKLHIVDLSNNSLTQILPGTLINLTNLTHLYLHNNKFTFIPDQSFDQLFQLQEITL 222 + +L ++ ++N F+ +F L +L+ +TL Sbjct: 276 -------------------AFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTL 312 >gi|5729718 trophoblast glycoprotein [Homo sapiens] Length = 420 Score = 72.8 bits (177), Expect = 6e-13 Identities = 70/258 (27%), Positives = 115/258 (44%), Gaps = 43/258 (16%) Query: 26 CPLQCICTERHRHVDCSGRNLSTLPSGLQENIIHLNLSYNHFTDL----HNQLTQYTNLR 81 CP C C+E R V C RNL+ +P+ L + +L L+ N L + L Sbjct: 62 CPALCECSEAARTVKCVNRNLTEVPTDLPAYVRNLFLTGNQLAVLPAGAFARRPPLAELA 121 Query: 82 TLDISNNRLESLPA----HLPRSLWNMSAANNNIKLLDKSDTAYQWNLKYLDVSKNMLEK 137 L++S +RL+ + A HLP SL + ++N L D S A+ + + ++E Sbjct: 122 ALNLSGSRLDEVRAGAFEHLP-SLRQLDLSHN--PLADLSPFAFSGSNASVSAPSPLVEL 178 Query: 138 V-----------------------VLIKNTLRSLEVLNLSSNKLWTVP----TNMPSKLH 170 + +L L+ L L L+SN +P +PS H Sbjct: 179 ILNHIVPPEDERQNRSFEGMVVAALLAGRALQGLRRLELASNHFLYLPRDVLAQLPSLRH 238 Query: 171 IVDLSNNSLTQILPGTLINLTNLTHLYLHNNKFTFIPDQSFDQLFQLQEITLY--NNRWS 228 + DLSNNSL + + NLT+L L+L +N + + + +L L I ++ NN W Sbjct: 239 L-DLSNNSLVSLTYVSFRNLTHLESLHLEDNALKVLHNGTLAELQGLPHIRVFLDNNPWV 297 Query: 229 CDHKQNITYLLKWMMETK 246 CD ++ ++ W+ ET+ Sbjct: 298 CD--CHMADMVTWLKETE 313 >gi|41349454 proline arginine-rich end leucine-rich repeat protein precursor [Homo sapiens] Length = 382 Score = 72.0 bits (175), Expect = 1e-12 Identities = 69/240 (28%), Positives = 108/240 (45%), Gaps = 33/240 (13%) Query: 20 PGILCICPLQCICT-ERHRHVDCSGRNLSTLPSGLQENIIHLNLSYNHFTDLHNQLTQY- 77 P I CP +C C + + C RNL +P + I +L L N T+L + Q Sbjct: 67 PSIFPDCPRECYCPPDFPSALYCDSRNLRKVPV-IPPRIHYLYLQNNFITELPVESFQNA 125 Query: 78 TNLRTLDISNNR------------------------LESLPAHLPRSLWNMSAANNNIKL 113 T LR +++ NNR LE +P+ LPR+L + + N+I Sbjct: 126 TGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLEEVPSALPRNLEQLRLSQNHISR 185 Query: 114 LDKSDTAYQWNLKYLDVSKNMLEKVVLIKNT---LRSLEVLNLSSNKLWTVPTNMPSKLH 170 + + NL LD+ N L V +T L++L LNL+ N L +P +P+ +H Sbjct: 186 IPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRVPTAIH 245 Query: 171 IVDLSNNSLTQILPGTLINLTNLTHLYLHNNKFT--FIPDQSFDQLFQLQEITLYNNRWS 228 + L +N + I G + NL + L+ NK T +P SF+ + L + L +NR S Sbjct: 246 QLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKNSFN-ISNLLVLHLSHNRIS 304 Score = 35.0 bits (79), Expect = 0.14 Identities = 23/75 (30%), Positives = 42/75 (56%), Gaps = 6/75 (8%) Query: 46 LSTLPSGLQE---NIIHLNLSYNHFTD--LHNQLTQYTNLRTLDISNNRLESLPAHLPRS 100 + T+P+G + N+ + L+YN TD L +NL L +S+NR+ S+PA + Sbjct: 254 IETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKNSFNISNLLVLHLSHNRISSVPA-INNR 312 Query: 101 LWNMSAANNNIKLLD 115 L ++ NN+I+ ++ Sbjct: 313 LEHLYLNNNSIEKIN 327 >gi|4506041 proline arginine-rich end leucine-rich repeat protein precursor [Homo sapiens] Length = 382 Score = 72.0 bits (175), Expect = 1e-12 Identities = 69/240 (28%), Positives = 108/240 (45%), Gaps = 33/240 (13%) Query: 20 PGILCICPLQCICT-ERHRHVDCSGRNLSTLPSGLQENIIHLNLSYNHFTDLHNQLTQY- 77 P I CP +C C + + C RNL +P + I +L L N T+L + Q Sbjct: 67 PSIFPDCPRECYCPPDFPSALYCDSRNLRKVPV-IPPRIHYLYLQNNFITELPVESFQNA 125 Query: 78 TNLRTLDISNNR------------------------LESLPAHLPRSLWNMSAANNNIKL 113 T LR +++ NNR LE +P+ LPR+L + + N+I Sbjct: 126 TGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLEEVPSALPRNLEQLRLSQNHISR 185 Query: 114 LDKSDTAYQWNLKYLDVSKNMLEKVVLIKNT---LRSLEVLNLSSNKLWTVPTNMPSKLH 170 + + NL LD+ N L V +T L++L LNL+ N L +P +P+ +H Sbjct: 186 IPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRVPTAIH 245 Query: 171 IVDLSNNSLTQILPGTLINLTNLTHLYLHNNKFT--FIPDQSFDQLFQLQEITLYNNRWS 228 + L +N + I G + NL + L+ NK T +P SF+ + L + L +NR S Sbjct: 246 QLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKNSFN-ISNLLVLHLSHNRIS 304 Score = 35.0 bits (79), Expect = 0.14 Identities = 23/75 (30%), Positives = 42/75 (56%), Gaps = 6/75 (8%) Query: 46 LSTLPSGLQE---NIIHLNLSYNHFTD--LHNQLTQYTNLRTLDISNNRLESLPAHLPRS 100 + T+P+G + N+ + L+YN TD L +NL L +S+NR+ S+PA + Sbjct: 254 IETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKNSFNISNLLVLHLSHNRISSVPA-INNR 312 Query: 101 LWNMSAANNNIKLLD 115 L ++ NN+I+ ++ Sbjct: 313 LEHLYLNNNSIEKIN 327 >gi|194306623 immunoglobulin superfamily containing leucine-rich repeat 2 [Homo sapiens] Length = 745 Score = 71.2 bits (173), Expect = 2e-12 Identities = 56/200 (28%), Positives = 93/200 (46%), Gaps = 36/200 (18%) Query: 15 LLFLTPGILCICPLQCICTERHRH--VDCSGRNLSTLPSGLQENIIHLNLSYNHFTDLHN 72 L++ G+ CP C C +++ H DC+ + L +P GL N+ L+LS N T L Sbjct: 9 LVWALLGVAGSCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSANKITVLRR 68 Query: 73 ----QLTQYTNLRTLDISNNRLESLPAHLPRSLWNMSAANNNIKLLDKSDTAYQWNLKYL 128 +TQ T SLW A+N ++ ++ A LK L Sbjct: 69 GAFADVTQVT---------------------SLW---LAHNEVRTVEPGALAVLSQLKNL 104 Query: 129 DVSKNMLEKVVLIK-NTLRSLEVLNLSSNKLWTVPTN----MPSKLHIVDLSNNSLTQIL 183 D+S N + L +L++L ++ N+L ++P + +P L + ++NN L + Sbjct: 105 DLSHNFISSFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPD-LRSLRINNNRLRTLA 163 Query: 184 PGTLINLTNLTHLYLHNNKF 203 PGT L+ L+HL L++N F Sbjct: 164 PGTFDALSALSHLQLYHNPF 183 >gi|194306621 immunoglobulin superfamily containing leucine-rich repeat 2 [Homo sapiens] Length = 745 Score = 71.2 bits (173), Expect = 2e-12 Identities = 56/200 (28%), Positives = 93/200 (46%), Gaps = 36/200 (18%) Query: 15 LLFLTPGILCICPLQCICTERHRH--VDCSGRNLSTLPSGLQENIIHLNLSYNHFTDLHN 72 L++ G+ CP C C +++ H DC+ + L +P GL N+ L+LS N T L Sbjct: 9 LVWALLGVAGSCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSANKITVLRR 68 Query: 73 ----QLTQYTNLRTLDISNNRLESLPAHLPRSLWNMSAANNNIKLLDKSDTAYQWNLKYL 128 +TQ T SLW A+N ++ ++ A LK L Sbjct: 69 GAFADVTQVT---------------------SLW---LAHNEVRTVEPGALAVLSQLKNL 104 Query: 129 DVSKNMLEKVVLIK-NTLRSLEVLNLSSNKLWTVPTN----MPSKLHIVDLSNNSLTQIL 183 D+S N + L +L++L ++ N+L ++P + +P L + ++NN L + Sbjct: 105 DLSHNFISSFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPD-LRSLRINNNRLRTLA 163 Query: 184 PGTLINLTNLTHLYLHNNKF 203 PGT L+ L+HL L++N F Sbjct: 164 PGTFDALSALSHLQLYHNPF 183 >gi|39930401 immunoglobulin superfamily containing leucine-rich repeat 2 [Homo sapiens] Length = 745 Score = 71.2 bits (173), Expect = 2e-12 Identities = 56/200 (28%), Positives = 93/200 (46%), Gaps = 36/200 (18%) Query: 15 LLFLTPGILCICPLQCICTERHRH--VDCSGRNLSTLPSGLQENIIHLNLSYNHFTDLHN 72 L++ G+ CP C C +++ H DC+ + L +P GL N+ L+LS N T L Sbjct: 9 LVWALLGVAGSCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSANKITVLRR 68 Query: 73 ----QLTQYTNLRTLDISNNRLESLPAHLPRSLWNMSAANNNIKLLDKSDTAYQWNLKYL 128 +TQ T SLW A+N ++ ++ A LK L Sbjct: 69 GAFADVTQVT---------------------SLW---LAHNEVRTVEPGALAVLSQLKNL 104 Query: 129 DVSKNMLEKVVLIK-NTLRSLEVLNLSSNKLWTVPTN----MPSKLHIVDLSNNSLTQIL 183 D+S N + L +L++L ++ N+L ++P + +P L + ++NN L + Sbjct: 105 DLSHNFISSFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPD-LRSLRINNNRLRTLA 163 Query: 184 PGTLINLTNLTHLYLHNNKF 203 PGT L+ L+HL L++N F Sbjct: 164 PGTFDALSALSHLQLYHNPF 183 >gi|194306618 immunoglobulin superfamily containing leucine-rich repeat 2 [Homo sapiens] Length = 745 Score = 71.2 bits (173), Expect = 2e-12 Identities = 56/200 (28%), Positives = 93/200 (46%), Gaps = 36/200 (18%) Query: 15 LLFLTPGILCICPLQCICTERHRH--VDCSGRNLSTLPSGLQENIIHLNLSYNHFTDLHN 72 L++ G+ CP C C +++ H DC+ + L +P GL N+ L+LS N T L Sbjct: 9 LVWALLGVAGSCPEPCACVDKYAHQFADCAYKELREVPEGLPANVTTLSLSANKITVLRR 68 Query: 73 ----QLTQYTNLRTLDISNNRLESLPAHLPRSLWNMSAANNNIKLLDKSDTAYQWNLKYL 128 +TQ T SLW A+N ++ ++ A LK L Sbjct: 69 GAFADVTQVT---------------------SLW---LAHNEVRTVEPGALAVLSQLKNL 104 Query: 129 DVSKNMLEKVVLIK-NTLRSLEVLNLSSNKLWTVPTN----MPSKLHIVDLSNNSLTQIL 183 D+S N + L +L++L ++ N+L ++P + +P L + ++NN L + Sbjct: 105 DLSHNFISSFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPD-LRSLRINNNRLRTLA 163 Query: 184 PGTLINLTNLTHLYLHNNKF 203 PGT L+ L+HL L++N F Sbjct: 164 PGTFDALSALSHLQLYHNPF 183 >gi|38490688 immunoglobulin superfamily, member 10 [Homo sapiens] Length = 2623 Score = 71.2 bits (173), Expect = 2e-12 Identities = 69/249 (27%), Positives = 112/249 (44%), Gaps = 48/249 (19%) Query: 14 ILLFLTPGILCICPLQCIC---TERHRHVDCSGRNLSTLPSGLQENIIHLNLSYNHFTDL 70 I L TPG CP +C C TE H C+ R L+++P + N+ +NL YN L Sbjct: 18 ICLVATPGGKA-CPRRCACYMPTEVH----CTFRYLTSIPDSIPPNVERINLGYNSLVRL 72 Query: 71 -HNQLTQYTNLRTLDISNNRLESLPAHLPRSLWNMSAANNNIKLLDKSDTAYQWNLKYLD 129 + T L L + +N + ++P DK+ + Q L+ L Sbjct: 73 METDFSGLTKLELLMLHSNGIHTIP--------------------DKTFSDLQ-ALQVLK 111 Query: 130 VSKNMLEKVVLIKNT---LRSLEVLNLSSNKLWTVPTNM---PSKLHIVDLSNNSLTQIL 183 +S N + K L K+T LRSL L++ N + + + + L +V L N LT++ Sbjct: 112 MSYNKVRK--LQKDTFYGLRSLTRLHMDHNNIEFINPEVFYGLNFLRLVHLEGNQLTKLH 169 Query: 184 PGTLINLTNLT--------HLYLHNNKFTFIPDQSFDQLFQLQEITLYNNRWSCDHKQNI 235 P T ++L+ L LYL +N T +P + + L + L+ N W+CD ++ Sbjct: 170 PDTFVSLSYLQIFKISFIKFLYLSDNFLTSLPQEMVSYMPDLDSLYLHGNPWTCD--CHL 227 Query: 236 TYLLKWMME 244 +L W+ E Sbjct: 228 KWLSDWIQE 236 >gi|221136985 SLIT and NTRK-like family, member 2 [Homo sapiens] Length = 845 Score = 70.5 bits (171), Expect = 3e-12 Identities = 92/384 (23%), Positives = 154/384 (40%), Gaps = 55/384 (14%) Query: 25 ICPLQCICTERHR--HVDCSGRNLST--LPSGLQENIIHLNLSYNHFTDLH-NQLTQYTN 79 IC ++C+C E+ +++C + +T L Q I L L+ N T L+ N+ Y+N Sbjct: 28 ICKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNYSN 87 Query: 80 LRTLDISNNRLESLPAHLPRSLWNMSAANNNIKLLDKSDTAYQWNLKYLDVSKNMLEKVV 139 TL + NN L+ + + A + +K LK L ++ N LE + Sbjct: 88 AVTLHLGNNGLQEI----------RTGAFSGLK-----------TLKRLHLNNNKLE--I 124 Query: 140 LIKNT---LRSLEVLNLSSNKLWTVPTNMPSKLHIVD--LSNNSLTQILPGTLINLTNLT 194 L ++T L SLE L N + + SKL+ + + N++L LP + LT Sbjct: 125 LREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLT 184 Query: 195 HLYLHNNKFTFIPDQS-FDQLFQLQEITLYNNRWSCDHKQNITYLLKWMMETKAHVIGTP 253 HL L N+ +P + + + EI L N W+C ++ L W+ V Sbjct: 185 HLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNC--TCDLLPLKAWLDTITVFVGEIV 242 Query: 254 CST-------QISSLKEHNMYPTPSGFTSSLFTVSGMQTVDTINSLSVVTQPKV--TKIP 304 C T ++ L ++ P S SS G + LS P + T+ P Sbjct: 243 CETPFRLHGKDVTQLTRQDLCPRKSASDSS---QRGSHADTHVQRLSPTMNPALNPTRAP 299 Query: 305 KQYR----TKETTFGATLSKDTTFTSTDKAF---VPYPEDTSTETINSHEAAAATLTIHL 357 K R T T+SKD + P P + + + +++ L ++ Sbjct: 300 KASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNC 359 Query: 358 QDGMVTNTSLTSSTKSSPTPMTLS 381 Q+ TN S +SP + L+ Sbjct: 360 QERKFTNISDLQPKPTSPKKLYLT 383 Score = 57.4 bits (137), Expect = 3e-08 Identities = 61/218 (27%), Positives = 98/218 (44%), Gaps = 38/218 (17%) Query: 26 CPLQCICTERHR----HVDCSGR---NLSTL-PSGLQENIIHLNLSYNHFTDLHNQLTQY 77 CP C+CT + +V+C R N+S L P ++L +Y T N L +Y Sbjct: 340 CPSSCVCTSQSSDNGLNVNCQERKFTNISDLQPKPTSPKKLYLTGNYLQ-TVYKNDLLEY 398 Query: 78 TNLRTLDISNNRL----ESLPAHLPRSLWNMSAANNNIKLLDKSDTAYQWNLKYLDVSKN 133 ++L L + NNR+ E +L SL + N +++L S +L+YL + N Sbjct: 399 SSLDLLHLGNNRIAVIQEGAFTNLT-SLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYN 457 Query: 134 MLEKVV-LIKNTLRSLEVLNLSSNKLWTVPTNMPSKLHIVDLSNNSLTQILPGTLINLTN 192 +++++ L + L +L++L L NN+L + LP + T Sbjct: 458 VIKEIKPLTFDALINLQLLFL----------------------NNNLLRSLPDNIFGGTA 495 Query: 193 LTHLYLHNNKFTFIPDQS-FDQLFQLQEITLYNNRWSC 229 LT L L NN F+ +P + DQL +I L N W C Sbjct: 496 LTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDC 533 >gi|221136981 SLIT and NTRK-like family, member 2 [Homo sapiens] Length = 845 Score = 70.5 bits (171), Expect = 3e-12 Identities = 92/384 (23%), Positives = 154/384 (40%), Gaps = 55/384 (14%) Query: 25 ICPLQCICTERHR--HVDCSGRNLST--LPSGLQENIIHLNLSYNHFTDLH-NQLTQYTN 79 IC ++C+C E+ +++C + +T L Q I L L+ N T L+ N+ Y+N Sbjct: 28 ICKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNYSN 87 Query: 80 LRTLDISNNRLESLPAHLPRSLWNMSAANNNIKLLDKSDTAYQWNLKYLDVSKNMLEKVV 139 TL + NN L+ + + A + +K LK L ++ N LE + Sbjct: 88 AVTLHLGNNGLQEI----------RTGAFSGLK-----------TLKRLHLNNNKLE--I 124 Query: 140 LIKNT---LRSLEVLNLSSNKLWTVPTNMPSKLHIVD--LSNNSLTQILPGTLINLTNLT 194 L ++T L SLE L N + + SKL+ + + N++L LP + LT Sbjct: 125 LREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLT 184 Query: 195 HLYLHNNKFTFIPDQS-FDQLFQLQEITLYNNRWSCDHKQNITYLLKWMMETKAHVIGTP 253 HL L N+ +P + + + EI L N W+C ++ L W+ V Sbjct: 185 HLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNC--TCDLLPLKAWLDTITVFVGEIV 242 Query: 254 CST-------QISSLKEHNMYPTPSGFTSSLFTVSGMQTVDTINSLSVVTQPKV--TKIP 304 C T ++ L ++ P S SS G + LS P + T+ P Sbjct: 243 CETPFRLHGKDVTQLTRQDLCPRKSASDSS---QRGSHADTHVQRLSPTMNPALNPTRAP 299 Query: 305 KQYR----TKETTFGATLSKDTTFTSTDKAF---VPYPEDTSTETINSHEAAAATLTIHL 357 K R T T+SKD + P P + + + +++ L ++ Sbjct: 300 KASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNC 359 Query: 358 QDGMVTNTSLTSSTKSSPTPMTLS 381 Q+ TN S +SP + L+ Sbjct: 360 QERKFTNISDLQPKPTSPKKLYLT 383 Score = 57.4 bits (137), Expect = 3e-08 Identities = 61/218 (27%), Positives = 98/218 (44%), Gaps = 38/218 (17%) Query: 26 CPLQCICTERHR----HVDCSGR---NLSTL-PSGLQENIIHLNLSYNHFTDLHNQLTQY 77 CP C+CT + +V+C R N+S L P ++L +Y T N L +Y Sbjct: 340 CPSSCVCTSQSSDNGLNVNCQERKFTNISDLQPKPTSPKKLYLTGNYLQ-TVYKNDLLEY 398 Query: 78 TNLRTLDISNNRL----ESLPAHLPRSLWNMSAANNNIKLLDKSDTAYQWNLKYLDVSKN 133 ++L L + NNR+ E +L SL + N +++L S +L+YL + N Sbjct: 399 SSLDLLHLGNNRIAVIQEGAFTNLT-SLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYN 457 Query: 134 MLEKVV-LIKNTLRSLEVLNLSSNKLWTVPTNMPSKLHIVDLSNNSLTQILPGTLINLTN 192 +++++ L + L +L++L L NN+L + LP + T Sbjct: 458 VIKEIKPLTFDALINLQLLFL----------------------NNNLLRSLPDNIFGGTA 495 Query: 193 LTHLYLHNNKFTFIPDQS-FDQLFQLQEITLYNNRWSC 229 LT L L NN F+ +P + DQL +I L N W C Sbjct: 496 LTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDC 533 >gi|221136977 SLIT and NTRK-like family, member 2 [Homo sapiens] Length = 845 Score = 70.5 bits (171), Expect = 3e-12 Identities = 92/384 (23%), Positives = 154/384 (40%), Gaps = 55/384 (14%) Query: 25 ICPLQCICTERHR--HVDCSGRNLST--LPSGLQENIIHLNLSYNHFTDLH-NQLTQYTN 79 IC ++C+C E+ +++C + +T L Q I L L+ N T L+ N+ Y+N Sbjct: 28 ICKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNYSN 87 Query: 80 LRTLDISNNRLESLPAHLPRSLWNMSAANNNIKLLDKSDTAYQWNLKYLDVSKNMLEKVV 139 TL + NN L+ + + A + +K LK L ++ N LE + Sbjct: 88 AVTLHLGNNGLQEI----------RTGAFSGLK-----------TLKRLHLNNNKLE--I 124 Query: 140 LIKNT---LRSLEVLNLSSNKLWTVPTNMPSKLHIVD--LSNNSLTQILPGTLINLTNLT 194 L ++T L SLE L N + + SKL+ + + N++L LP + LT Sbjct: 125 LREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLT 184 Query: 195 HLYLHNNKFTFIPDQS-FDQLFQLQEITLYNNRWSCDHKQNITYLLKWMMETKAHVIGTP 253 HL L N+ +P + + + EI L N W+C ++ L W+ V Sbjct: 185 HLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNC--TCDLLPLKAWLDTITVFVGEIV 242 Query: 254 CST-------QISSLKEHNMYPTPSGFTSSLFTVSGMQTVDTINSLSVVTQPKV--TKIP 304 C T ++ L ++ P S SS G + LS P + T+ P Sbjct: 243 CETPFRLHGKDVTQLTRQDLCPRKSASDSS---QRGSHADTHVQRLSPTMNPALNPTRAP 299 Query: 305 KQYR----TKETTFGATLSKDTTFTSTDKAF---VPYPEDTSTETINSHEAAAATLTIHL 357 K R T T+SKD + P P + + + +++ L ++ Sbjct: 300 KASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNC 359 Query: 358 QDGMVTNTSLTSSTKSSPTPMTLS 381 Q+ TN S +SP + L+ Sbjct: 360 QERKFTNISDLQPKPTSPKKLYLT 383 Score = 57.4 bits (137), Expect = 3e-08 Identities = 61/218 (27%), Positives = 98/218 (44%), Gaps = 38/218 (17%) Query: 26 CPLQCICTERHR----HVDCSGR---NLSTL-PSGLQENIIHLNLSYNHFTDLHNQLTQY 77 CP C+CT + +V+C R N+S L P ++L +Y T N L +Y Sbjct: 340 CPSSCVCTSQSSDNGLNVNCQERKFTNISDLQPKPTSPKKLYLTGNYLQ-TVYKNDLLEY 398 Query: 78 TNLRTLDISNNRL----ESLPAHLPRSLWNMSAANNNIKLLDKSDTAYQWNLKYLDVSKN 133 ++L L + NNR+ E +L SL + N +++L S +L+YL + N Sbjct: 399 SSLDLLHLGNNRIAVIQEGAFTNLT-SLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYN 457 Query: 134 MLEKVV-LIKNTLRSLEVLNLSSNKLWTVPTNMPSKLHIVDLSNNSLTQILPGTLINLTN 192 +++++ L + L +L++L L NN+L + LP + T Sbjct: 458 VIKEIKPLTFDALINLQLLFL----------------------NNNLLRSLPDNIFGGTA 495 Query: 193 LTHLYLHNNKFTFIPDQS-FDQLFQLQEITLYNNRWSC 229 LT L L NN F+ +P + DQL +I L N W C Sbjct: 496 LTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDC 533 >gi|221136973 SLIT and NTRK-like family, member 2 [Homo sapiens] Length = 845 Score = 70.5 bits (171), Expect = 3e-12 Identities = 92/384 (23%), Positives = 154/384 (40%), Gaps = 55/384 (14%) Query: 25 ICPLQCICTERHR--HVDCSGRNLST--LPSGLQENIIHLNLSYNHFTDLH-NQLTQYTN 79 IC ++C+C E+ +++C + +T L Q I L L+ N T L+ N+ Y+N Sbjct: 28 ICKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNYSN 87 Query: 80 LRTLDISNNRLESLPAHLPRSLWNMSAANNNIKLLDKSDTAYQWNLKYLDVSKNMLEKVV 139 TL + NN L+ + + A + +K LK L ++ N LE + Sbjct: 88 AVTLHLGNNGLQEI----------RTGAFSGLK-----------TLKRLHLNNNKLE--I 124 Query: 140 LIKNT---LRSLEVLNLSSNKLWTVPTNMPSKLHIVD--LSNNSLTQILPGTLINLTNLT 194 L ++T L SLE L N + + SKL+ + + N++L LP + LT Sbjct: 125 LREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLT 184 Query: 195 HLYLHNNKFTFIPDQS-FDQLFQLQEITLYNNRWSCDHKQNITYLLKWMMETKAHVIGTP 253 HL L N+ +P + + + EI L N W+C ++ L W+ V Sbjct: 185 HLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNC--TCDLLPLKAWLDTITVFVGEIV 242 Query: 254 CST-------QISSLKEHNMYPTPSGFTSSLFTVSGMQTVDTINSLSVVTQPKV--TKIP 304 C T ++ L ++ P S SS G + LS P + T+ P Sbjct: 243 CETPFRLHGKDVTQLTRQDLCPRKSASDSS---QRGSHADTHVQRLSPTMNPALNPTRAP 299 Query: 305 KQYR----TKETTFGATLSKDTTFTSTDKAF---VPYPEDTSTETINSHEAAAATLTIHL 357 K R T T+SKD + P P + + + +++ L ++ Sbjct: 300 KASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNC 359 Query: 358 QDGMVTNTSLTSSTKSSPTPMTLS 381 Q+ TN S +SP + L+ Sbjct: 360 QERKFTNISDLQPKPTSPKKLYLT 383 Score = 57.4 bits (137), Expect = 3e-08 Identities = 61/218 (27%), Positives = 98/218 (44%), Gaps = 38/218 (17%) Query: 26 CPLQCICTERHR----HVDCSGR---NLSTL-PSGLQENIIHLNLSYNHFTDLHNQLTQY 77 CP C+CT + +V+C R N+S L P ++L +Y T N L +Y Sbjct: 340 CPSSCVCTSQSSDNGLNVNCQERKFTNISDLQPKPTSPKKLYLTGNYLQ-TVYKNDLLEY 398 Query: 78 TNLRTLDISNNRL----ESLPAHLPRSLWNMSAANNNIKLLDKSDTAYQWNLKYLDVSKN 133 ++L L + NNR+ E +L SL + N +++L S +L+YL + N Sbjct: 399 SSLDLLHLGNNRIAVIQEGAFTNLT-SLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYN 457 Query: 134 MLEKVV-LIKNTLRSLEVLNLSSNKLWTVPTNMPSKLHIVDLSNNSLTQILPGTLINLTN 192 +++++ L + L +L++L L NN+L + LP + T Sbjct: 458 VIKEIKPLTFDALINLQLLFL----------------------NNNLLRSLPDNIFGGTA 495 Query: 193 LTHLYLHNNKFTFIPDQS-FDQLFQLQEITLYNNRWSC 229 LT L L NN F+ +P + DQL +I L N W C Sbjct: 496 LTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDC 533 >gi|221136969 SLIT and NTRK-like family, member 2 [Homo sapiens] Length = 845 Score = 70.5 bits (171), Expect = 3e-12 Identities = 92/384 (23%), Positives = 154/384 (40%), Gaps = 55/384 (14%) Query: 25 ICPLQCICTERHR--HVDCSGRNLST--LPSGLQENIIHLNLSYNHFTDLH-NQLTQYTN 79 IC ++C+C E+ +++C + +T L Q I L L+ N T L+ N+ Y+N Sbjct: 28 ICKIRCLCEEKENVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNYSN 87 Query: 80 LRTLDISNNRLESLPAHLPRSLWNMSAANNNIKLLDKSDTAYQWNLKYLDVSKNMLEKVV 139 TL + NN L+ + + A + +K LK L ++ N LE + Sbjct: 88 AVTLHLGNNGLQEI----------RTGAFSGLK-----------TLKRLHLNNNKLE--I 124 Query: 140 LIKNT---LRSLEVLNLSSNKLWTVPTNMPSKLHIVD--LSNNSLTQILPGTLINLTNLT 194 L ++T L SLE L N + + SKL+ + + N++L LP + LT Sbjct: 125 LREDTFLGLESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLT 184 Query: 195 HLYLHNNKFTFIPDQS-FDQLFQLQEITLYNNRWSCDHKQNITYLLKWMMETKAHVIGTP 253 HL L N+ +P + + + EI L N W+C ++ L W+ V Sbjct: 185 HLDLRGNRLKVMPFAGVLEHIGGIMEIQLEENPWNC--TCDLLPLKAWLDTITVFVGEIV 242 Query: 254 CST-------QISSLKEHNMYPTPSGFTSSLFTVSGMQTVDTINSLSVVTQPKV--TKIP 304 C T ++ L ++ P S SS G + LS P + T+ P Sbjct: 243 CETPFRLHGKDVTQLTRQDLCPRKSASDSS---QRGSHADTHVQRLSPTMNPALNPTRAP 299 Query: 305 KQYR----TKETTFGATLSKDTTFTSTDKAF---VPYPEDTSTETINSHEAAAATLTIHL 357 K R T T+SKD + P P + + + +++ L ++ Sbjct: 300 KASRPPKMRNRPTPRVTVSKDRQSFGPIMVYQTKSPVPLTCPSSCVCTSQSSDNGLNVNC 359 Query: 358 QDGMVTNTSLTSSTKSSPTPMTLS 381 Q+ TN S +SP + L+ Sbjct: 360 QERKFTNISDLQPKPTSPKKLYLT 383 Score = 57.4 bits (137), Expect = 3e-08 Identities = 61/218 (27%), Positives = 98/218 (44%), Gaps = 38/218 (17%) Query: 26 CPLQCICTERHR----HVDCSGR---NLSTL-PSGLQENIIHLNLSYNHFTDLHNQLTQY 77 CP C+CT + +V+C R N+S L P ++L +Y T N L +Y Sbjct: 340 CPSSCVCTSQSSDNGLNVNCQERKFTNISDLQPKPTSPKKLYLTGNYLQ-TVYKNDLLEY 398 Query: 78 TNLRTLDISNNRL----ESLPAHLPRSLWNMSAANNNIKLLDKSDTAYQWNLKYLDVSKN 133 ++L L + NNR+ E +L SL + N +++L S +L+YL + N Sbjct: 399 SSLDLLHLGNNRIAVIQEGAFTNLT-SLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYN 457 Query: 134 MLEKVV-LIKNTLRSLEVLNLSSNKLWTVPTNMPSKLHIVDLSNNSLTQILPGTLINLTN 192 +++++ L + L +L++L L NN+L + LP + T Sbjct: 458 VIKEIKPLTFDALINLQLLFL----------------------NNNLLRSLPDNIFGGTA 495 Query: 193 LTHLYLHNNKFTFIPDQS-FDQLFQLQEITLYNNRWSC 229 LT L L NN F+ +P + DQL +I L N W C Sbjct: 496 LTRLNLRNNHFSHLPVKGVLDQLPAFIQIDLQENPWDC 533 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.129 0.380 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,956,499 Number of Sequences: 37866 Number of extensions: 690172 Number of successful extensions: 6050 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 232 Number of HSP's successfully gapped in prelim test: 96 Number of HSP's that attempted gapping in prelim test: 2144 Number of HSP's gapped (non-prelim): 1692 length of query: 440 length of database: 18,247,518 effective HSP length: 105 effective length of query: 335 effective length of database: 14,271,588 effective search space: 4780981980 effective search space used: 4780981980 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.