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Search of human proteins with 51873058
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|51873058 A kinase (PRKA) anchor protein 2 isoform 1 [Homo
sapiens]
(948 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|51873058 A kinase (PRKA) anchor protein 2 isoform 1 [Homo sap... 1895 0.0
gi|22325356 PALM2-AKAP2 protein isoform 2 [Homo sapiens] 1782 0.0
gi|6005709 PALM2-AKAP2 protein isoform 1 [Homo sapiens] 1773 0.0
gi|211971074 A kinase (PRKA) anchor protein 2 isoform 2 [Homo sa... 1705 0.0
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 52 3e-06
gi|29826321 adducin 1 (alpha) isoform b [Homo sapiens] 50 1e-05
gi|109240550 paraspeckle protein 1 [Homo sapiens] 49 3e-05
gi|221139761 zinc finger protein 853 [Homo sapiens] 48 5e-05
gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens] 47 6e-05
gi|150170670 piccolo isoform 2 [Homo sapiens] 47 6e-05
gi|150378539 piccolo isoform 1 [Homo sapiens] 47 6e-05
gi|29826319 adducin 1 (alpha) isoform a [Homo sapiens] 47 1e-04
gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo sa... 46 1e-04
gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo sa... 46 1e-04
gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo sa... 46 1e-04
gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo sap... 46 1e-04
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 46 2e-04
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 45 2e-04
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 45 3e-04
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 45 3e-04
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 45 3e-04
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 45 3e-04
gi|21493022 A kinase (PRKA) anchor protein 12 isoform 1 [Homo sa... 45 3e-04
gi|21493024 A kinase (PRKA) anchor protein 12 isoform 2 [Homo sa... 45 3e-04
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 45 3e-04
gi|112421108 capicua homolog [Homo sapiens] 45 3e-04
gi|221219020 NYD-SP11 protein [Homo sapiens] 45 4e-04
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 45 4e-04
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 45 4e-04
gi|41406089 SRY-box 13 [Homo sapiens] 45 4e-04
>gi|51873058 A kinase (PRKA) anchor protein 2 isoform 1 [Homo
sapiens]
Length = 948
Score = 1895 bits (4908), Expect = 0.0
Identities = 948/948 (100%), Positives = 948/948 (100%)
Query: 1 MRWPQPGAAARLPPESPGPPESPGPPEREAAAARRWTGAEPQDCAPGSGRPEKPPQLSED 60
MRWPQPGAAARLPPESPGPPESPGPPEREAAAARRWTGAEPQDCAPGSGRPEKPPQLSED
Sbjct: 1 MRWPQPGAAARLPPESPGPPESPGPPEREAAAARRWTGAEPQDCAPGSGRPEKPPQLSED 60
Query: 61 DIWLKSEGDNYSATLLEPAASSLSPDHKNMEIEVSVAECKSVPGITSTPHPMDHPSAFYS 120
DIWLKSEGDNYSATLLEPAASSLSPDHKNMEIEVSVAECKSVPGITSTPHPMDHPSAFYS
Sbjct: 61 DIWLKSEGDNYSATLLEPAASSLSPDHKNMEIEVSVAECKSVPGITSTPHPMDHPSAFYS 120
Query: 121 PPHNGLLTDHHESLDNDVAREIRYLDEVLEANCCDSAVDGTYNGTSSPEPGAVVLVGGLS 180
PPHNGLLTDHHESLDNDVAREIRYLDEVLEANCCDSAVDGTYNGTSSPEPGAVVLVGGLS
Sbjct: 121 PPHNGLLTDHHESLDNDVAREIRYLDEVLEANCCDSAVDGTYNGTSSPEPGAVVLVGGLS 180
Query: 181 PPVHEATQPEPTERTASRQAPPHIELSNSSPDPMAEAERTNGHSPSQPRDALGDSLQVPV 240
PPVHEATQPEPTERTASRQAPPHIELSNSSPDPMAEAERTNGHSPSQPRDALGDSLQVPV
Sbjct: 181 PPVHEATQPEPTERTASRQAPPHIELSNSSPDPMAEAERTNGHSPSQPRDALGDSLQVPV 240
Query: 241 SPSSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRP 300
SPSSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRP
Sbjct: 241 SPSSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRP 300
Query: 301 SEEMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKER 360
SEEMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKER
Sbjct: 301 SEEMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKER 360
Query: 361 RAQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQ 420
RAQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQ
Sbjct: 361 RAQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQ 420
Query: 421 LMENSRQAVAKGQSTPRLFSIKPFYRPLGSVNSDKPLTNPRPPSVGGPPEDSGASAAKGQ 480
LMENSRQAVAKGQSTPRLFSIKPFYRPLGSVNSDKPLTNPRPPSVGGPPEDSGASAAKGQ
Sbjct: 421 LMENSRQAVAKGQSTPRLFSIKPFYRPLGSVNSDKPLTNPRPPSVGGPPEDSGASAAKGQ 480
Query: 481 KSPGALETPSAAGSQGNTASQGKEGPYSEPSKRGPLSKLWAEDGEFTSARAVLTVVKDDD 540
KSPGALETPSAAGSQGNTASQGKEGPYSEPSKRGPLSKLWAEDGEFTSARAVLTVVKDDD
Sbjct: 481 KSPGALETPSAAGSQGNTASQGKEGPYSEPSKRGPLSKLWAEDGEFTSARAVLTVVKDDD 540
Query: 541 HGILDQFSRSVNVSLTQEELDSGLDELSVRSQDTTVLETLSNDFSMDNISDSGASNETTN 600
HGILDQFSRSVNVSLTQEELDSGLDELSVRSQDTTVLETLSNDFSMDNISDSGASNETTN
Sbjct: 541 HGILDQFSRSVNVSLTQEELDSGLDELSVRSQDTTVLETLSNDFSMDNISDSGASNETTN 600
Query: 601 ALQENSLADFSLPQTPQTDNPSEGRGEGVSKSFSDHGFYSPSSTLGDSPLVDDPLEYQAG 660
ALQENSLADFSLPQTPQTDNPSEGRGEGVSKSFSDHGFYSPSSTLGDSPLVDDPLEYQAG
Sbjct: 601 ALQENSLADFSLPQTPQTDNPSEGRGEGVSKSFSDHGFYSPSSTLGDSPLVDDPLEYQAG 660
Query: 661 LLVQNAIQQAIAEQVDKAVSKTSRDGAEQQGPEATVEEAEAAAFGSEKPQSMFEPPQVSS 720
LLVQNAIQQAIAEQVDKAVSKTSRDGAEQQGPEATVEEAEAAAFGSEKPQSMFEPPQVSS
Sbjct: 661 LLVQNAIQQAIAEQVDKAVSKTSRDGAEQQGPEATVEEAEAAAFGSEKPQSMFEPPQVSS 720
Query: 721 PVQEKRDVLPKILPAEDRALRERGPPQPLPAVQPSGPINMEETRPEGSYFSKYSEAAELR 780
PVQEKRDVLPKILPAEDRALRERGPPQPLPAVQPSGPINMEETRPEGSYFSKYSEAAELR
Sbjct: 721 PVQEKRDVLPKILPAEDRALRERGPPQPLPAVQPSGPINMEETRPEGSYFSKYSEAAELR 780
Query: 781 STASLLATQESDVMVGPFKLRSRKQRTLSMIEEEIRAAQEREEELKRQRQVLQSTQSPRT 840
STASLLATQESDVMVGPFKLRSRKQRTLSMIEEEIRAAQEREEELKRQRQVLQSTQSPRT
Sbjct: 781 STASLLATQESDVMVGPFKLRSRKQRTLSMIEEEIRAAQEREEELKRQRQVLQSTQSPRT 840
Query: 841 KNAPSLPSRTCYKTAPGKIEKVKPPPSPTTEGPSLQPDLAPEEAAGTQRPKNLMQTLMED 900
KNAPSLPSRTCYKTAPGKIEKVKPPPSPTTEGPSLQPDLAPEEAAGTQRPKNLMQTLMED
Sbjct: 841 KNAPSLPSRTCYKTAPGKIEKVKPPPSPTTEGPSLQPDLAPEEAAGTQRPKNLMQTLMED 900
Query: 901 YETHKSKRRERMDDSSVLEATRVNRRKSALALRWEAGIYANQEEEDNE 948
YETHKSKRRERMDDSSVLEATRVNRRKSALALRWEAGIYANQEEEDNE
Sbjct: 901 YETHKSKRRERMDDSSVLEATRVNRRKSALALRWEAGIYANQEEEDNE 948
>gi|22325356 PALM2-AKAP2 protein isoform 2 [Homo sapiens]
Length = 1090
Score = 1782 bits (4615), Expect = 0.0
Identities = 904/936 (96%), Positives = 906/936 (96%), Gaps = 9/936 (0%)
Query: 22 SPGPPEREAAAARRWTGAEPQDCAPGSGRPE---------KPPQLSEDDIWLKSEGDNYS 72
SPG AA W ++ S E KPPQLSEDDIWLKSEGDNYS
Sbjct: 155 SPGQDGTSRAAGVGWENVLLKEGESASNATETSGPDMTIKKPPQLSEDDIWLKSEGDNYS 214
Query: 73 ATLLEPAASSLSPDHKNMEIEVSVAECKSVPGITSTPHPMDHPSAFYSPPHNGLLTDHHE 132
ATLLEPAASSLSPDHKNMEIEVSVAECKSVPGITSTPHPMDHPSAFYSPPHNGLLTDHHE
Sbjct: 215 ATLLEPAASSLSPDHKNMEIEVSVAECKSVPGITSTPHPMDHPSAFYSPPHNGLLTDHHE 274
Query: 133 SLDNDVAREIRYLDEVLEANCCDSAVDGTYNGTSSPEPGAVVLVGGLSPPVHEATQPEPT 192
SLDNDVAREIRYLDEVLEANCCDSAVDGTYNGTSSPEPGAVVLVGGLSPPVHEATQPEPT
Sbjct: 275 SLDNDVAREIRYLDEVLEANCCDSAVDGTYNGTSSPEPGAVVLVGGLSPPVHEATQPEPT 334
Query: 193 ERTASRQAPPHIELSNSSPDPMAEAERTNGHSPSQPRDALGDSLQVPVSPSSTTSSRCSS 252
ERTASRQAPPHIELSNSSPDPMAEAERTNGHSPSQPRDALGDSLQVPVSPSSTTSSRCSS
Sbjct: 335 ERTASRQAPPHIELSNSSPDPMAEAERTNGHSPSQPRDALGDSLQVPVSPSSTTSSRCSS 394
Query: 253 RDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERR 312
RDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERR
Sbjct: 395 RDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERR 454
Query: 313 ELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQ 372
ELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQ
Sbjct: 455 ELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQ 514
Query: 373 LQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQAVAKG 432
LQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQAVAKG
Sbjct: 515 LQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQAVAKG 574
Query: 433 QSTPRLFSIKPFYRPLGSVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKSPGALETPSAA 492
QSTPRLFSIKPFYRPLGSVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKSPGALETPSAA
Sbjct: 575 QSTPRLFSIKPFYRPLGSVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKSPGALETPSAA 634
Query: 493 GSQGNTASQGKEGPYSEPSKRGPLSKLWAEDGEFTSARAVLTVVKDDDHGILDQFSRSVN 552
GSQGNTASQGKEGPYSEPSKRGPLSKLWAEDGEFTSARAVLTVVKDDDHGILDQFSRSVN
Sbjct: 635 GSQGNTASQGKEGPYSEPSKRGPLSKLWAEDGEFTSARAVLTVVKDDDHGILDQFSRSVN 694
Query: 553 VSLTQEELDSGLDELSVRSQDTTVLETLSNDFSMDNISDSGASNETTNALQENSLADFSL 612
VSLTQEELDSGLDELSVRSQDTTVLETLSNDFSMDNISDSGASNETTNALQENSLADFSL
Sbjct: 695 VSLTQEELDSGLDELSVRSQDTTVLETLSNDFSMDNISDSGASNETTNALQENSLADFSL 754
Query: 613 PQTPQTDNPSEGRGEGVSKSFSDHGFYSPSSTLGDSPLVDDPLEYQAGLLVQNAIQQAIA 672
PQTPQTDNPSEGRGEGVSKSFSDHGFYSPSSTLGDSPLVDDPLEYQAGLLVQNAIQQAIA
Sbjct: 755 PQTPQTDNPSEGRGEGVSKSFSDHGFYSPSSTLGDSPLVDDPLEYQAGLLVQNAIQQAIA 814
Query: 673 EQVDKAVSKTSRDGAEQQGPEATVEEAEAAAFGSEKPQSMFEPPQVSSPVQEKRDVLPKI 732
EQVDKAVSKTSRDGAEQQGPEATVEEAEAAAFGSEKPQSMFEPPQVSSPVQEKRDVLPKI
Sbjct: 815 EQVDKAVSKTSRDGAEQQGPEATVEEAEAAAFGSEKPQSMFEPPQVSSPVQEKRDVLPKI 874
Query: 733 LPAEDRALRERGPPQPLPAVQPSGPINMEETRPEGSYFSKYSEAAELRSTASLLATQESD 792
LPAEDRALRERGPPQPLPAVQPSGPINMEETRPEGSYFSKYSEAAELRSTASLLATQESD
Sbjct: 875 LPAEDRALRERGPPQPLPAVQPSGPINMEETRPEGSYFSKYSEAAELRSTASLLATQESD 934
Query: 793 VMVGPFKLRSRKQRTLSMIEEEIRAAQEREEELKRQRQVLQSTQSPRTKNAPSLPSRTCY 852
VMVGPFKLRSRKQRTLSMIEEEIRAAQEREEELKRQRQVLQSTQSPRTKNAPSLPSRTCY
Sbjct: 935 VMVGPFKLRSRKQRTLSMIEEEIRAAQEREEELKRQRQVLQSTQSPRTKNAPSLPSRTCY 994
Query: 853 KTAPGKIEKVKPPPSPTTEGPSLQPDLAPEEAAGTQRPKNLMQTLMEDYETHKSKRRERM 912
KTAPGKIEKVKPPPSPTTEGPSLQPDLAPEEAAGTQRPKNLMQTLMEDYETHKSKRRERM
Sbjct: 995 KTAPGKIEKVKPPPSPTTEGPSLQPDLAPEEAAGTQRPKNLMQTLMEDYETHKSKRRERM 1054
Query: 913 DDSSVLEATRVNRRKSALALRWEAGIYANQEEEDNE 948
DDSSVLEATRVNRRKSALALRWEAGIYANQEEEDNE
Sbjct: 1055 DDSSVLEATRVNRRKSALALRWEAGIYANQEEEDNE 1090
>gi|6005709 PALM2-AKAP2 protein isoform 1 [Homo sapiens]
Length = 1103
Score = 1773 bits (4591), Expect = 0.0
Identities = 904/949 (95%), Positives = 906/949 (95%), Gaps = 22/949 (2%)
Query: 22 SPGPPEREAAAARRWTGAEPQDCAPGSGRPE---------KPPQLSEDDIWLKSEGDNYS 72
SPG AA W ++ S E KPPQLSEDDIWLKSEGDNYS
Sbjct: 155 SPGQDGTSRAAGVGWENVLLKEGESASNATETSGPDMTIKKPPQLSEDDIWLKSEGDNYS 214
Query: 73 ATLLEPAASSLSPDHKNMEIEVSVAECKSVPGITSTPHPMDHPSAFYSPPHNGLLTDHHE 132
ATLLEPAASSLSPDHKNMEIEVSVAECKSVPGITSTPHPMDHPSAFYSPPHNGLLTDHHE
Sbjct: 215 ATLLEPAASSLSPDHKNMEIEVSVAECKSVPGITSTPHPMDHPSAFYSPPHNGLLTDHHE 274
Query: 133 SLDNDVAREIRYLDEVLEANCCDSAVDGTYNGTSSPEPGAVVLVGGLSPPVHEATQPEPT 192
SLDNDVAREIRYLDEVLEANCCDSAVDGTYNGTSSPEPGAVVLVGGLSPPVHEATQPEPT
Sbjct: 275 SLDNDVAREIRYLDEVLEANCCDSAVDGTYNGTSSPEPGAVVLVGGLSPPVHEATQPEPT 334
Query: 193 ERTASRQAPPHIELSNSSPDPMAEAERTNGHSPSQPRDALGDSLQVPVSPSSTTSSRCSS 252
ERTASRQAPPHIELSNSSPDPMAEAERTNGHSPSQPRDALGDSLQVPVSPSSTTSSRCSS
Sbjct: 335 ERTASRQAPPHIELSNSSPDPMAEAERTNGHSPSQPRDALGDSLQVPVSPSSTTSSRCSS 394
Query: 253 RDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERR 312
RDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERR
Sbjct: 395 RDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERR 454
Query: 313 ELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQ 372
ELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQ
Sbjct: 455 ELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQ 514
Query: 373 LQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQAVAKG 432
LQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQAVAKG
Sbjct: 515 LQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQAVAKG 574
Query: 433 QSTPRLFSIKPFYRPLGSVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKSPGALETPSAA 492
QSTPRLFSIKPFYRPLGSVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKSPGALETPSAA
Sbjct: 575 QSTPRLFSIKPFYRPLGSVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKSPGALETPSAA 634
Query: 493 GSQGNTASQGKEGPYSEPSKRGPLSKLWAEDGEFTSARAVLTVVKDDDHGILDQFSRSVN 552
GSQGNTASQGKEGPYSEPSKRGPLSKLWAEDGEFTSARAVLTVVKDDDHGILDQFSRSVN
Sbjct: 635 GSQGNTASQGKEGPYSEPSKRGPLSKLWAEDGEFTSARAVLTVVKDDDHGILDQFSRSVN 694
Query: 553 VSLTQEELDSGLDELSVRSQDTTVLETLSNDFSMDNISDSGASNETTNALQENSLADFSL 612
VSLTQEELDSGLDELSVRSQDTTVLETLSNDFSMDNISDSGASNETTNALQENSLADFSL
Sbjct: 695 VSLTQEELDSGLDELSVRSQDTTVLETLSNDFSMDNISDSGASNETTNALQENSLADFSL 754
Query: 613 PQTPQTDNPSEGRGEGVSKSFSDHGFYSPSSTLGDSPLVDDPLEYQAGLLVQNAIQQAIA 672
PQTPQTDNPSEGRGEGVSKSFSDHGFYSPSSTLGDSPLVDDPLEYQAGLLVQNAIQQAIA
Sbjct: 755 PQTPQTDNPSEGRGEGVSKSFSDHGFYSPSSTLGDSPLVDDPLEYQAGLLVQNAIQQAIA 814
Query: 673 EQVDKAVSKTSRDGAEQQGPEATVEEAEAAAFGSEKPQSMFEPPQVSSPVQEKRDVLPKI 732
EQVDKAVSKTSRDGAEQQGPEATVEEAEAAAFGSEKPQSMFEPPQVSSPVQEKRDVLPKI
Sbjct: 815 EQVDKAVSKTSRDGAEQQGPEATVEEAEAAAFGSEKPQSMFEPPQVSSPVQEKRDVLPKI 874
Query: 733 LPAEDRALRERGPPQPLPAVQPSGPINMEETRPEGSYFSKYSEAAELRSTASLLATQESD 792
LPAEDRALRERGPPQPLPAVQPSGPINMEETRPEGSYFSKYSEAAELRSTASLLATQESD
Sbjct: 875 LPAEDRALRERGPPQPLPAVQPSGPINMEETRPEGSYFSKYSEAAELRSTASLLATQESD 934
Query: 793 VMVGPFKLRSRKQRTLSMIEEEIRAAQEREEELKRQRQVLQSTQSPRTKNAPSLPSRTCY 852
VMVGPFKLRSRKQRTLSMIEEEIRAAQEREEELKRQRQVLQSTQSPRTKNAPSLPSRTCY
Sbjct: 935 VMVGPFKLRSRKQRTLSMIEEEIRAAQEREEELKRQRQVLQSTQSPRTKNAPSLPSRTCY 994
Query: 853 KTAPGKIEKVKPPPSPTTEGPSLQPDLAPEEAAGTQRPKNLMQTLMEDYETHKSKRRERM 912
KTAPGKIEKVKPPPSPTTEGPSLQPDLAPEEAAGTQRPKNLMQTLMEDYETHKSKRRERM
Sbjct: 995 KTAPGKIEKVKPPPSPTTEGPSLQPDLAPEEAAGTQRPKNLMQTLMEDYETHKSKRRERM 1054
Query: 913 DDSS-------------VLEATRVNRRKSALALRWEAGIYANQEEEDNE 948
DDSS VLEATRVNRRKSALALRWEAGIYANQEEEDNE
Sbjct: 1055 DDSSYTSKLLSCKVTSEVLEATRVNRRKSALALRWEAGIYANQEEEDNE 1103
>gi|211971074 A kinase (PRKA) anchor protein 2 isoform 2 [Homo
sapiens]
Length = 859
Score = 1705 bits (4416), Expect = 0.0
Identities = 859/859 (100%), Positives = 859/859 (100%)
Query: 90 MEIEVSVAECKSVPGITSTPHPMDHPSAFYSPPHNGLLTDHHESLDNDVAREIRYLDEVL 149
MEIEVSVAECKSVPGITSTPHPMDHPSAFYSPPHNGLLTDHHESLDNDVAREIRYLDEVL
Sbjct: 1 MEIEVSVAECKSVPGITSTPHPMDHPSAFYSPPHNGLLTDHHESLDNDVAREIRYLDEVL 60
Query: 150 EANCCDSAVDGTYNGTSSPEPGAVVLVGGLSPPVHEATQPEPTERTASRQAPPHIELSNS 209
EANCCDSAVDGTYNGTSSPEPGAVVLVGGLSPPVHEATQPEPTERTASRQAPPHIELSNS
Sbjct: 61 EANCCDSAVDGTYNGTSSPEPGAVVLVGGLSPPVHEATQPEPTERTASRQAPPHIELSNS 120
Query: 210 SPDPMAEAERTNGHSPSQPRDALGDSLQVPVSPSSTTSSRCSSRDGEFTLTTLKKEAKFE 269
SPDPMAEAERTNGHSPSQPRDALGDSLQVPVSPSSTTSSRCSSRDGEFTLTTLKKEAKFE
Sbjct: 121 SPDPMAEAERTNGHSPSQPRDALGDSLQVPVSPSSTTSSRCSSRDGEFTLTTLKKEAKFE 180
Query: 270 LRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAK 329
LRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAK
Sbjct: 181 LRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAK 240
Query: 330 WWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQLCTAPA 389
WWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQLCTAPA
Sbjct: 241 WWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQLCTAPA 300
Query: 390 SSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQAVAKGQSTPRLFSIKPFYRPLG 449
SSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQAVAKGQSTPRLFSIKPFYRPLG
Sbjct: 301 SSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQAVAKGQSTPRLFSIKPFYRPLG 360
Query: 450 SVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKEGPYSE 509
SVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKEGPYSE
Sbjct: 361 SVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKEGPYSE 420
Query: 510 PSKRGPLSKLWAEDGEFTSARAVLTVVKDDDHGILDQFSRSVNVSLTQEELDSGLDELSV 569
PSKRGPLSKLWAEDGEFTSARAVLTVVKDDDHGILDQFSRSVNVSLTQEELDSGLDELSV
Sbjct: 421 PSKRGPLSKLWAEDGEFTSARAVLTVVKDDDHGILDQFSRSVNVSLTQEELDSGLDELSV 480
Query: 570 RSQDTTVLETLSNDFSMDNISDSGASNETTNALQENSLADFSLPQTPQTDNPSEGRGEGV 629
RSQDTTVLETLSNDFSMDNISDSGASNETTNALQENSLADFSLPQTPQTDNPSEGRGEGV
Sbjct: 481 RSQDTTVLETLSNDFSMDNISDSGASNETTNALQENSLADFSLPQTPQTDNPSEGRGEGV 540
Query: 630 SKSFSDHGFYSPSSTLGDSPLVDDPLEYQAGLLVQNAIQQAIAEQVDKAVSKTSRDGAEQ 689
SKSFSDHGFYSPSSTLGDSPLVDDPLEYQAGLLVQNAIQQAIAEQVDKAVSKTSRDGAEQ
Sbjct: 541 SKSFSDHGFYSPSSTLGDSPLVDDPLEYQAGLLVQNAIQQAIAEQVDKAVSKTSRDGAEQ 600
Query: 690 QGPEATVEEAEAAAFGSEKPQSMFEPPQVSSPVQEKRDVLPKILPAEDRALRERGPPQPL 749
QGPEATVEEAEAAAFGSEKPQSMFEPPQVSSPVQEKRDVLPKILPAEDRALRERGPPQPL
Sbjct: 601 QGPEATVEEAEAAAFGSEKPQSMFEPPQVSSPVQEKRDVLPKILPAEDRALRERGPPQPL 660
Query: 750 PAVQPSGPINMEETRPEGSYFSKYSEAAELRSTASLLATQESDVMVGPFKLRSRKQRTLS 809
PAVQPSGPINMEETRPEGSYFSKYSEAAELRSTASLLATQESDVMVGPFKLRSRKQRTLS
Sbjct: 661 PAVQPSGPINMEETRPEGSYFSKYSEAAELRSTASLLATQESDVMVGPFKLRSRKQRTLS 720
Query: 810 MIEEEIRAAQEREEELKRQRQVLQSTQSPRTKNAPSLPSRTCYKTAPGKIEKVKPPPSPT 869
MIEEEIRAAQEREEELKRQRQVLQSTQSPRTKNAPSLPSRTCYKTAPGKIEKVKPPPSPT
Sbjct: 721 MIEEEIRAAQEREEELKRQRQVLQSTQSPRTKNAPSLPSRTCYKTAPGKIEKVKPPPSPT 780
Query: 870 TEGPSLQPDLAPEEAAGTQRPKNLMQTLMEDYETHKSKRRERMDDSSVLEATRVNRRKSA 929
TEGPSLQPDLAPEEAAGTQRPKNLMQTLMEDYETHKSKRRERMDDSSVLEATRVNRRKSA
Sbjct: 781 TEGPSLQPDLAPEEAAGTQRPKNLMQTLMEDYETHKSKRRERMDDSSVLEATRVNRRKSA 840
Query: 930 LALRWEAGIYANQEEEDNE 948
LALRWEAGIYANQEEEDNE
Sbjct: 841 LALRWEAGIYANQEEEDNE 859
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 52.0 bits (123), Expect = 3e-06
Identities = 57/235 (24%), Positives = 93/235 (39%), Gaps = 41/235 (17%)
Query: 180 SPPVHEATQPEPTERTASRQAPPHI-ELSNSSP----DPMAEAERTNGHSPSQP-RDALG 233
S P + +PEP + S +AP H+ + P P+ N P P +D
Sbjct: 1122 SEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQK 1181
Query: 234 DSLQVPVSPSSTTSSRCSSRDGEFTL---TTLKKEAKFELRAFHEDKKPSKLFEDDEHEK 290
+ PV+P + TT AK +F + ++ ++ E +E EK
Sbjct: 1182 QEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQFRRAAR--EKEEREK 1239
Query: 291 EQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLES 350
++ E E EKER +++ + + DE+ LE
Sbjct: 1240 ------ALKAQAEHAEKEKERL----------------------RQERMRSREDEDALEQ 1271
Query: 351 HKKYKERKERRAQQEQLLLQKQLQQQQQQPP--SQLCTAPASSHERASMIDKAKE 403
++ E RR +Q+Q Q+Q QQQQQQ + T A S + SM+D+ +E
Sbjct: 1272 ARRAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQQRE 1326
>gi|29826321 adducin 1 (alpha) isoform b [Homo sapiens]
Length = 768
Score = 49.7 bits (117), Expect = 1e-05
Identities = 76/337 (22%), Positives = 125/337 (37%), Gaps = 40/337 (11%)
Query: 191 PTERTASRQAPPHIELSNSSPDPMAEAERTNGHSPSQP--------RDALGDSLQVPVS- 241
P + +Q NS A E NG SP D + LQ S
Sbjct: 432 PLRHSFQKQQREKTRWLNSGRGDEASEEGQNGSSPKSKTKVWTNITHDHVKPLLQSLSSG 491
Query: 242 ---PSSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKV 298
PS T+ + DG T T+ L + K + + E+ I+
Sbjct: 492 VCVPSCITNCLWTKEDGHRTSTSAVPNLFVPLNT---NPKEVQEMRNKIREQNLQDIKTA 548
Query: 299 RPSEEMLELEKERRELIRSQAVKKNPGIAAKWWNP--------PQEKTIEEQLDEEHLES 350
P ++L R L++ + V + I K + P P T L + LE
Sbjct: 549 GPQSQVLCGVVMDRSLVQGELVTASKAIIEKEYQPHVIVSTTGPNPFTT---LTDRELEE 605
Query: 351 HKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQI 410
+++ ERK++ +++ L + +Q+++ PP Q PA H S K +ED+V E
Sbjct: 606 YRREVERKQKGSEEN---LDEAREQKEKSPPDQ----PAVPHPPPSTPIKLEEDLVPEPT 658
Query: 411 ---DFSAARKQFQLMENSRQAVAKGQSTPRLFSIKPFYRPLGSVNSDKPLTNPRPPSVGG 467
D AA + L + S ++ P L + +RP + + P
Sbjct: 659 TGDDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAP 718
Query: 468 PPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKE 504
E++ SA + GA P + GS G + S+ K+
Sbjct: 719 VAEEAAPSAVE----EGAAADPGSDGSPGKSPSKKKK 751
Score = 32.0 bits (71), Expect = 2.8
Identities = 24/103 (23%), Positives = 43/103 (41%), Gaps = 3/103 (2%)
Query: 656 EYQAGLLVQNAIQQAIAEQVDKAVSKTSRD-GAEQQGPEATVEEAEAAAFGSEKPQSMFE 714
EYQ ++V D+ + + R+ +Q+G E ++EA S Q
Sbjct: 580 EYQPHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVP 639
Query: 715 PPQVSSPVQEKRDVLPKILPAEDRALRERGPPQPLPAVQPSGP 757
P S+P++ + D++P+ +D P LP + P P
Sbjct: 640 HPPPSTPIKLEEDLVPEPTTGDDSDAATFKP--TLPDLSPDEP 680
>gi|109240550 paraspeckle protein 1 [Homo sapiens]
Length = 523
Score = 48.5 bits (114), Expect = 3e-05
Identities = 68/305 (22%), Positives = 116/305 (38%), Gaps = 44/305 (14%)
Query: 242 PSSTTSSRCSSRDGEFTLTTLKKEAKFE-LRAFH-EDKKPSKLFEDDE--HEKEQYCIRK 297
P+ RC DG F LTT + E + F ED P KL + + H++ + R
Sbjct: 208 PARKALERCG--DGAFLLTTTPRPVIVEPMEQFDDEDGLPEKLMQKTQQYHKEREQPPRF 265
Query: 298 VRPS----------EEMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEH 347
+P + + E+EK++RE + +EK E H
Sbjct: 266 AQPGTFEFEYASRWKALDEMEKQQREQVDRNI------------REAKEKLEAEMEAARH 313
Query: 348 LESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERAS---MIDKAKED 404
H+ R++ +QE+L ++L+ Q+ Q Q+ H R + + +E+
Sbjct: 314 --EHQLMLMRQDLMRRQEELRRLEELRNQELQKRKQIQLRHEEEHRRREEEMIRHREQEE 371
Query: 405 IVTEQIDFSAARKQFQLMENSRQAVAKGQSTPRLFSIKPFYRPLGSVNSDKPLTNPRPPS 464
+ +Q F MEN Q + G PR +I +G S P N PP
Sbjct: 372 LRRQQEGFKP-----NYMENREQEMRMGDMGPR-GAIN-----MGDAFSPAPAGNQGPPP 420
Query: 465 VGGPPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKEGPYSEPSKRGPLSKLWAEDG 524
+ G ++ A+ PG P A + G +++ +GP S++ + G
Sbjct: 421 MMGMNMNNRATIPGPPMGPGPAMGPEGAANMGTPMMPDNGAVHNDRFPQGPPSQMGSPMG 480
Query: 525 EFTSA 529
T +
Sbjct: 481 SRTGS 485
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 47.8 bits (112), Expect = 5e-05
Identities = 61/278 (21%), Positives = 123/278 (44%), Gaps = 38/278 (13%)
Query: 170 PGAVVLVGGLSPPVHEATQPEPTERTASRQAPPHIELSNSSPDPMAE-AERTNG------ 222
PG L GG S + EP ER +S Q P + S+P +E AE T
Sbjct: 37 PGPDTLSGG-SGGSESQEEEEPQERNSSPQRP-----AVSAPVGASEIAEETRPGQRELQ 90
Query: 223 -----HSPSQPRDALGDSLQVPVSPSSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDK 277
P + + LQ P P + +DG+ L+ L++E + H++
Sbjct: 91 LQQLEQQPEPQQQPQHEQLQQP-QPHLELQQQ-PQQDGQQQLSQLQQEKHQSVH--HQEL 146
Query: 278 KPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEK 337
KP H+++Q ++V +E L++++ +L QA ++ Q++
Sbjct: 147 KPELQLM---HQQQQLQPQQV---QEQQRLQQQQEQLQTQQAQEQQV--------LQQQE 192
Query: 338 TIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQ--QPPSQLCTAPASSHERA 395
+++Q+ E+ L ++ + ++++ QQ++ L Q+Q QQQQ+ Q QL +
Sbjct: 193 QLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQ 252
Query: 396 SMIDKAKEDIVTEQIDFSAARKQFQLMENSRQAVAKGQ 433
++ + + + + ++ A+ Q QL+ ++ + + Q
Sbjct: 253 QLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQ 290
Score = 38.9 bits (89), Expect = 0.023
Identities = 46/239 (19%), Positives = 100/239 (41%), Gaps = 28/239 (11%)
Query: 287 EHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQL--- 343
E ++ Q + + +E L+ +++++ L + Q + + P +E+ +E +L
Sbjct: 268 EQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPV 327
Query: 344 ---DEEHLESHKKYKERK-ERRAQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERASMID 399
E+ LE ++ ER+ E QQEQ LQ +LQ++ QQ QL ++ ++
Sbjct: 328 DLGSEQELEQQRQELERQQELERQQEQRQLQLKLQEELQQLEQQL-------EQQQQQLE 380
Query: 400 KAKEDIVTEQIDFSAARKQFQL----------MENSRQAVAKGQSTP----RLFSIKPFY 445
+ + + ++ A +++ QL +E A G + P + P Y
Sbjct: 381 QQEVQLELTPVELGAQQQEVQLELTPVQPELQLELVPAAGGGGAAVPGAPAAVVVAPPGY 440
Query: 446 RPLGSVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKE 504
+ + + P ++ GP + + A+ ++ A + P+ G G S+ +
Sbjct: 441 VVVQELMVLPAVAAPAVVAIPGPAGSAALTPARQRRRRRARDRPTICGECGKGFSRSTD 499
>gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens]
Length = 1312
Score = 47.4 bits (111), Expect = 6e-05
Identities = 83/367 (22%), Positives = 134/367 (36%), Gaps = 57/367 (15%)
Query: 190 EPTERTASRQAPPHIELSNSSPDPMAEAERTNGHSPSQPRDALGDSLQVPVSPSSTTSSR 249
+PTER Q HI+ S E E +S S+ D DS PSS +
Sbjct: 292 QPTERQVRIQLKDHIDRSRKKRGEKEETEYE--YSGSEEED---DSHGEEGEPSSIMNV- 345
Query: 250 CSSRDGEFTLTT----LKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEML 305
GE TL L++E K A K+ +L + + + E + + + +
Sbjct: 346 ----PGESTLRREFLRLQQENKSNSEAL---KQQQQLQQQQQRDPEAHIKHLLHQRQRRI 398
Query: 306 ELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEE------QLDEEHLESHKKYK---- 355
E +KE R + Q ++ K Q++ +E+ + + E ++YK
Sbjct: 399 EEQKEERRRVEEQQRRERE--QRKLQEKEQQRRLEDMQALRREEERRQAEREQEYKRKQL 456
Query: 356 ------ERKERRAQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERASM------IDKAKE 403
ER +R+ QQE L+ QQQQQQ + +R + ++ A +
Sbjct: 457 EEQRQSERLQRQLQQEHAYLKSLQQQQQQQQLQKQQQQQLLPGDRKPLYHYGRGMNPADK 516
Query: 404 DIVTEQIDFSAARKQFQLMENSRQAVAKGQST---PRLFSIKPFYRPLGSVNSDKPLTNP 460
+++ R + +NS A +K ST P + P P G ++ P+ P
Sbjct: 517 PAWAREVE---ERTRMNKQQNSPLAKSKPGSTGPEPPIPQASP--GPPGPLSQTPPMQRP 571
Query: 461 RPPSVG-------GPPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKEGPYSEPSKR 513
P G P + A A P A+ P+A S + P SE
Sbjct: 572 VEPQEGPHKSLQDQPTRNLAAFPASHDPDP-AIPAPTATPSARGAVIRQNSDPTSEGPGP 630
Query: 514 GPLSKLW 520
P W
Sbjct: 631 SPNPPAW 637
Score = 31.6 bits (70), Expect = 3.7
Identities = 35/149 (23%), Positives = 59/149 (39%), Gaps = 3/149 (2%)
Query: 736 EDRALRERGPPQPLPAVQPSGPINMEETRPEGSYFSKYSEAAELRSTASLLATQESDVMV 795
ED + E G P + V + E R + S SEA L+ L Q+ D
Sbjct: 329 EDDSHGEEGEPSSIMNVPGESTLRREFLRLQQENKSN-SEA--LKQQQQLQQQQQRDPEA 385
Query: 796 GPFKLRSRKQRTLSMIEEEIRAAQEREEELKRQRQVLQSTQSPRTKNAPSLPSRTCYKTA 855
L ++QR + +EE R +E++ + QR++ + Q R ++ +L + A
Sbjct: 386 HIKHLLHQRQRRIEEQKEERRRVEEQQRREREQRKLQEKEQQRRLEDMQALRREEERRQA 445
Query: 856 PGKIEKVKPPPSPTTEGPSLQPDLAPEEA 884
+ E + + LQ L E A
Sbjct: 446 EREQEYKRKQLEEQRQSERLQRQLQQEHA 474
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 47.4 bits (111), Expect = 6e-05
Identities = 119/601 (19%), Positives = 226/601 (37%), Gaps = 106/601 (17%)
Query: 15 ESPGPPESPGPPEREAAAARRWTGAE-PQDCAPGSGRPE-----KPPQLSEDDIWLKSEG 68
ES SP P + + + E Q+ + GSG E + ++S D+ SE
Sbjct: 1515 ESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSED 1574
Query: 69 DNYSATLLEPAASSLSPDHKNMEIEVSVAECKSVPGITSTPHPMDHPSAFYSPPHNGLLT 128
D + L+ +SS K E K IT+ H L
Sbjct: 1575 DEFIRNQLKEISSSTESQKKE--------ETKGKGKITAGKH-------------RRLTR 1613
Query: 129 DHHESLDNDVAREIRYLDEVLEANCCDSAVDGTYNGTSSPEPGAVVLVGG---------- 178
S+D D R + DE EA D + + Y T S E +V+ GG
Sbjct: 1614 KSSTSIDEDAGRRHSWHDEDDEA--FDESPELKYRETKSQESEELVVTGGGGLRRFKTIE 1671
Query: 179 LSPPVHEATQPEPTERTASR--QAPPHIELSNSSPDPMAEAERTNGHSPSQPRDALGDSL 236
L+ + + E +++ S P +E+ + + P +R+ G S S
Sbjct: 1672 LNSTIADKYSAESSQKKTSLYFDEEPELEMESLTDSP---EDRSRGEGSSSLH---ASSF 1725
Query: 237 QVPVSPSSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIR 296
SP+S +S D + + + K E+K + +A H P +D E+E+
Sbjct: 1726 TPGTSPTSVSSL---DEDSDSSPSHKKGESKQQRKARHRPHGPLLPTIEDSSEEEE---- 1778
Query: 297 KVRPSEEMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKE 356
+R EE+L+ ++++RE IE+Q + S K K+
Sbjct: 1779 -LREEEELLKEQEKQRE-------------------------IEQQ--QRKSSSKKSKKD 1810
Query: 357 RKERRAQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAAR 416
+ E RAQ+ +++ + PPS L S E AS ++ ++ E++ S+
Sbjct: 1811 KDELRAQRR--------RERPKTPPSNL-----SPIEDASPTEELRQAAEMEELHRSSCS 1857
Query: 417 KQFQLMENSRQAVAKGQSTPRLFSIKPFYRPLGSVNSDKPLTNPRPPSVGGPPEDSGASA 476
+ +E+ + S ++ ++ Y+ +V+ L +P E S +
Sbjct: 1858 EYSPSIESDPEGFE--ISPEKIIEVQKVYKLPTAVS----LYSPTDEQSIMQKEGSQKAL 1911
Query: 477 AKGQKSPGALETPSAAGSQGNTASQGKEGPYSEPSKRGPLSKLW-----AEDGEFTSARA 531
++ + + A++ E EP G L + + ED S
Sbjct: 1912 KSAEEMYEEMMHKTHKYKAFPAANERDEVFEKEPLYGGMLIEDYIYESLVEDTYNGSVDG 1971
Query: 532 VLTVVKDDDHGILDQFSRSVNVSLTQEELDSGLDELSVRSQDTTVLETLSNDFSMDNISD 591
L +++++G + Q R + L+++ + + +++ ++ LE+L + ++I
Sbjct: 1972 SLLTRQEEENGFMQQKGREQKIRLSEQIYEDPMQKITDLQKEFYELESLHSVVPQEDIVS 2031
Query: 592 S 592
S
Sbjct: 2032 S 2032
Score = 43.9 bits (102), Expect = 7e-04
Identities = 207/1034 (20%), Positives = 365/1034 (35%), Gaps = 196/1034 (18%)
Query: 6 PGAAARLPPESPGPPESPGPPEREAAAARRWTGAEPQDCAPGSGRPEKPPQLSEDDIWLK 65
PGA + P PP S GPP+ TG P AP P +K
Sbjct: 960 PGAPMKQAPAPSQPPTSQGPPKS--------TGQAPP--APAKSIP------------VK 997
Query: 66 SEGDNYSATLLEPAASSLSPDHKNMEIEVSVAECKSVPGITSTPHPMDHPSAF------- 118
E +A LEP A +P K E E K +T+ P P+
Sbjct: 998 KETKAPAAEKLEPKAEQ-APTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPE 1056
Query: 119 --------------YSPPHNGLLTDHHESLDNDVA-REIRYLDEVLEANCCDSAVDGTYN 163
PP+ T+ + N +L E+ E C + +
Sbjct: 1057 STCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAIS 1116
Query: 164 GTSSPEPGAVVLVGGLSPPVHEATQPEPTERTASRQA-PPHIEL-SNSSPDPMAEAERTN 221
G + G + + + P PTE ++ + A PP ++L + EAE+
Sbjct: 1117 G----QLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKV- 1171
Query: 222 GHSPSQPRDALGDSLQVPVSPSSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDKKPSK 281
+ + ++L + P T+ + + E L K A E + E+KK
Sbjct: 1172 ------ILEKVKETLSMEKIPPMVTTDQ---KQEESKLEKDKASALQEKKPLPEEKKLIP 1222
Query: 282 LFEDDEHEKEQYCIRKVRPSEEMLEL---------EKERRELIRSQ---AVKKNPGIAA- 328
E E+++ + + +P+ E +L E+++ +L++SQ A +K G A
Sbjct: 1223 EEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAP 1282
Query: 329 ---KWWNPPQEKT------IEEQLDEEHLESHKKYKERKER--RAQQEQLLLQKQLQQ-- 375
+ PQ K + L +E ++ K KE+ + A+ +Q+ K+ +
Sbjct: 1283 KTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKE 1342
Query: 376 ---------QQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSR 426
QQ + P L SS +S + + I T++ D K+ + S
Sbjct: 1343 DDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESS 1402
Query: 427 QA----VAKGQSTPRLFSIKPFYRPLGSVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKS 482
+ +AK +ST L ++ L S+K T P S P + K Q
Sbjct: 1403 PSSPSDLAKLESTV-LSILEAQASTLADEKSEKK-TQPHEVSPEQPKDQE-----KTQSL 1455
Query: 483 PGALETPSAAGSQGNTASQGKEGPYSEPSKRGPLSKLWAEDGEFTSARAVLTVVKDDDHG 542
LE + + + K+ + + P SK E EF + + +
Sbjct: 1456 SETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFVDD----ITTRREPYD 1511
Query: 543 ILDQFSRSVNVSLTQEEL-----DSGLDELSVR-SQDTTVLETLSNDFSMDNISDSGASN 596
+++ S S N + Q + S DE SQ + E ++ +D AS
Sbjct: 1512 SVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASG 1571
Query: 597 ETTNALQENSLADFSLPQTPQTDNPSEGRGEGVSKSFSDHGFYSPSSTLGDSPLVDDPLE 656
+ N L + S + ++ E +G+G + SST ++
Sbjct: 1572 SEDDEFIRNQLKEIS--SSTESQKKEETKGKGKITAGKHRRLTRKSST---------SID 1620
Query: 657 YQAGLLVQNAIQQAIAEQVDKAVSKTSRDGAEQQGPEATVEEA----------------- 699
AG +++ E D++ R+ Q+ E V
Sbjct: 1621 EDAGR--RHSWHDEDDEAFDESPELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIAD 1678
Query: 700 EAAAFGSEKPQSMF--EPPQV------SSPVQEKR----------DVLPKILPAEDRALR 741
+ +A S+K S++ E P++ SP R P P +L
Sbjct: 1679 KYSAESSQKKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLD 1738
Query: 742 ERGPPQPLPAVQPSGPINMEETRPEGSY---FSKYSEAAELRSTASLLATQESDVMVGPF 798
E P S RP G SE ELR LL QE +
Sbjct: 1739 EDSDSSPSHKKGESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQ 1798
Query: 799 KLRSRKQRTLSMIEEEIRAAQERE------------------EELKRQRQVLQSTQSPRT 840
+ +S +++ ++E+RA + RE EEL++ ++ + +S +
Sbjct: 1799 QRKSSSKKS-KKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCS 1857
Query: 841 KNAPSLPS-RTCYKTAPGKIEKV----KPPPSPTTEGPSLQPDLAPEEAAGTQRPKNLMQ 895
+ +PS+ S ++ +P KI +V K P + + P+ + + +E G+Q+ +
Sbjct: 1858 EYSPSIESDPEGFEISPEKIIEVQKVYKLPTAVSLYSPTDEQSIMQKE--GSQKALKSAE 1915
Query: 896 TLMED--YETHKSK 907
+ E+ ++THK K
Sbjct: 1916 EMYEEMMHKTHKYK 1929
Score = 32.0 bits (71), Expect = 2.8
Identities = 55/270 (20%), Positives = 106/270 (39%), Gaps = 47/270 (17%)
Query: 583 DFSMDNISDSG---ASNETTNALQENSLADFSLPQTPQT------DNPSEGRGEGVSKSF 633
+ M++++DS + E +++L +S + P + + +PS +GE +
Sbjct: 1698 ELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRK 1757
Query: 634 SDHGFYSPSSTLGDSPLVDDPLEYQAGLLVQNAIQQAIAEQVDKAVSKTSRDGAEQQGPE 693
+ H + P + ++ L + LL + Q+ I +Q K+ SK S+ ++ +
Sbjct: 1758 ARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQ 1817
Query: 694 ATVEEAEAAAFGSEKPQSMFEPPQVSSPVQEKRDVLPKILPAEDRALRERGPPQPLPAVQ 753
E + P S P + +SP +E R AE L + P++
Sbjct: 1818 RRRERPKT-------PPSNLSPIEDASPTEELRQA------AEMEELHRSSCSEYSPSI- 1863
Query: 754 PSGPINMEETRPEGSYFS-----KYSEAAELRSTASLLA-TQESDVMVGPFKLRSRKQRT 807
E+ PEG S + + +L + SL + T E +M ++ K
Sbjct: 1864 --------ESDPEGFEISPEKIIEVQKVYKLPTAVSLYSPTDEQSIMQKEGSQKALKSAE 1915
Query: 808 LSMIEEEIR---------AAQEREEELKRQ 828
M EE + AA ER+E +++
Sbjct: 1916 -EMYEEMMHKTHKYKAFPAANERDEVFEKE 1944
Score = 30.8 bits (68), Expect = 6.3
Identities = 29/122 (23%), Positives = 60/122 (49%), Gaps = 24/122 (19%)
Query: 275 EDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAKWWNPP 334
EDK+ +L + E+E + K++ ELE ER+E+ R +
Sbjct: 3207 EDKQQQQL----DLERELLELEKIKQQRFAEELEWERQEIQRFRE--------------- 3247
Query: 335 QEKT-IEEQLDE-EHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQLCTAPASSH 392
QEK ++++L+E + ++ H +++ +ER+AQ +++++ QQQ Q+ H
Sbjct: 3248 QEKIMVQKKLEELQSMKQHLLFQQEEERQAQ---FMMRQETLAQQQLQLEQIQQLQQQLH 3304
Query: 393 ER 394
++
Sbjct: 3305 QQ 3306
Score = 30.4 bits (67), Expect = 8.2
Identities = 63/309 (20%), Positives = 111/309 (35%), Gaps = 50/309 (16%)
Query: 614 QTPQTDNPSEGRGEGVSKSFSDHGFYSPSSTLGDSPLVDDPLEYQA-------------- 659
Q+ + +P G+SKS + F S G SP E ++
Sbjct: 95 QSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMP 154
Query: 660 GLLVQNAIQQAIAEQVDKAVSKTSRDGAEQQGPEATVEEAEAAAFGSEKPQSMFEPPQVS 719
G L + A++ V+K + + E T ++ + KP+ + +PP
Sbjct: 155 GFLSEVNALSAVSSVVNK-FNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQ 213
Query: 720 SPVQEKRDVLPKILPAEDRALRERGPPQPLPAVQPSG----------PINMEETRPEGSY 769
P + +PK L++ G P+ + + QP PI P+ +
Sbjct: 214 QPPKP----IPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDH 269
Query: 770 FSKYSEAAELRSTASLLATQESDVMVGPFKLRSRKQRTLSMIEEEIRAAQEREEELKRQR 829
L+ AS T+++D++ G S + I++ ++ +
Sbjct: 270 AK-----LPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKS 324
Query: 830 QVLQSTQSPRTKNAPSLPSRTCYKTA--PGKIEKVKPPPSP--TTEGPS--LQPDLAPEE 883
Q P P+ PS A PG VKPP P TT+ P+ L P P +
Sbjct: 325 Q-------PGPAKPPAQPSGLTKPLAQQPGT---VKPPVQPPGTTKPPAQPLGPAKPPAQ 374
Query: 884 AAGTQRPKN 892
G+++P +
Sbjct: 375 QTGSEKPSS 383
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 47.4 bits (111), Expect = 6e-05
Identities = 119/601 (19%), Positives = 226/601 (37%), Gaps = 106/601 (17%)
Query: 15 ESPGPPESPGPPEREAAAARRWTGAE-PQDCAPGSGRPE-----KPPQLSEDDIWLKSEG 68
ES SP P + + + E Q+ + GSG E + ++S D+ SE
Sbjct: 1515 ESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSED 1574
Query: 69 DNYSATLLEPAASSLSPDHKNMEIEVSVAECKSVPGITSTPHPMDHPSAFYSPPHNGLLT 128
D + L+ +SS K E K IT+ H L
Sbjct: 1575 DEFIRNQLKEISSSTESQKKE--------ETKGKGKITAGKH-------------RRLTR 1613
Query: 129 DHHESLDNDVAREIRYLDEVLEANCCDSAVDGTYNGTSSPEPGAVVLVGG---------- 178
S+D D R + DE EA D + + Y T S E +V+ GG
Sbjct: 1614 KSSTSIDEDAGRRHSWHDEDDEA--FDESPELKYRETKSQESEELVVTGGGGLRRFKTIE 1671
Query: 179 LSPPVHEATQPEPTERTASR--QAPPHIELSNSSPDPMAEAERTNGHSPSQPRDALGDSL 236
L+ + + E +++ S P +E+ + + P +R+ G S S
Sbjct: 1672 LNSTIADKYSAESSQKKTSLYFDEEPELEMESLTDSP---EDRSRGEGSSSLH---ASSF 1725
Query: 237 QVPVSPSSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIR 296
SP+S +S D + + + K E+K + +A H P +D E+E+
Sbjct: 1726 TPGTSPTSVSSL---DEDSDSSPSHKKGESKQQRKARHRPHGPLLPTIEDSSEEEE---- 1778
Query: 297 KVRPSEEMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKE 356
+R EE+L+ ++++RE IE+Q + S K K+
Sbjct: 1779 -LREEEELLKEQEKQRE-------------------------IEQQ--QRKSSSKKSKKD 1810
Query: 357 RKERRAQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAAR 416
+ E RAQ+ +++ + PPS L S E AS ++ ++ E++ S+
Sbjct: 1811 KDELRAQRR--------RERPKTPPSNL-----SPIEDASPTEELRQAAEMEELHRSSCS 1857
Query: 417 KQFQLMENSRQAVAKGQSTPRLFSIKPFYRPLGSVNSDKPLTNPRPPSVGGPPEDSGASA 476
+ +E+ + S ++ ++ Y+ +V+ L +P E S +
Sbjct: 1858 EYSPSIESDPEGFE--ISPEKIIEVQKVYKLPTAVS----LYSPTDEQSIMQKEGSQKAL 1911
Query: 477 AKGQKSPGALETPSAAGSQGNTASQGKEGPYSEPSKRGPLSKLW-----AEDGEFTSARA 531
++ + + A++ E EP G L + + ED S
Sbjct: 1912 KSAEEMYEEMMHKTHKYKAFPAANERDEVFEKEPLYGGMLIEDYIYESLVEDTYNGSVDG 1971
Query: 532 VLTVVKDDDHGILDQFSRSVNVSLTQEELDSGLDELSVRSQDTTVLETLSNDFSMDNISD 591
L +++++G + Q R + L+++ + + +++ ++ LE+L + ++I
Sbjct: 1972 SLLTRQEEENGFMQQKGREQKIRLSEQIYEDPMQKITDLQKEFYELESLHSVVPQEDIVS 2031
Query: 592 S 592
S
Sbjct: 2032 S 2032
Score = 43.9 bits (102), Expect = 7e-04
Identities = 207/1034 (20%), Positives = 365/1034 (35%), Gaps = 196/1034 (18%)
Query: 6 PGAAARLPPESPGPPESPGPPEREAAAARRWTGAEPQDCAPGSGRPEKPPQLSEDDIWLK 65
PGA + P PP S GPP+ TG P AP P +K
Sbjct: 960 PGAPMKQAPAPSQPPTSQGPPKS--------TGQAPP--APAKSIP------------VK 997
Query: 66 SEGDNYSATLLEPAASSLSPDHKNMEIEVSVAECKSVPGITSTPHPMDHPSAF------- 118
E +A LEP A +P K E E K +T+ P P+
Sbjct: 998 KETKAPAAEKLEPKAEQ-APTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPE 1056
Query: 119 --------------YSPPHNGLLTDHHESLDNDVA-REIRYLDEVLEANCCDSAVDGTYN 163
PP+ T+ + N +L E+ E C + +
Sbjct: 1057 STCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAIS 1116
Query: 164 GTSSPEPGAVVLVGGLSPPVHEATQPEPTERTASRQA-PPHIEL-SNSSPDPMAEAERTN 221
G + G + + + P PTE ++ + A PP ++L + EAE+
Sbjct: 1117 G----QLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKV- 1171
Query: 222 GHSPSQPRDALGDSLQVPVSPSSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDKKPSK 281
+ + ++L + P T+ + + E L K A E + E+KK
Sbjct: 1172 ------ILEKVKETLSMEKIPPMVTTDQ---KQEESKLEKDKASALQEKKPLPEEKKLIP 1222
Query: 282 LFEDDEHEKEQYCIRKVRPSEEMLEL---------EKERRELIRSQ---AVKKNPGIAA- 328
E E+++ + + +P+ E +L E+++ +L++SQ A +K G A
Sbjct: 1223 EEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAP 1282
Query: 329 ---KWWNPPQEKT------IEEQLDEEHLESHKKYKERKER--RAQQEQLLLQKQLQQ-- 375
+ PQ K + L +E ++ K KE+ + A+ +Q+ K+ +
Sbjct: 1283 KTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKE 1342
Query: 376 ---------QQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSR 426
QQ + P L SS +S + + I T++ D K+ + S
Sbjct: 1343 DDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESS 1402
Query: 427 QA----VAKGQSTPRLFSIKPFYRPLGSVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKS 482
+ +AK +ST L ++ L S+K T P S P + K Q
Sbjct: 1403 PSSPSDLAKLESTV-LSILEAQASTLADEKSEKK-TQPHEVSPEQPKDQE-----KTQSL 1455
Query: 483 PGALETPSAAGSQGNTASQGKEGPYSEPSKRGPLSKLWAEDGEFTSARAVLTVVKDDDHG 542
LE + + + K+ + + P SK E EF + + +
Sbjct: 1456 SETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFVDD----ITTRREPYD 1511
Query: 543 ILDQFSRSVNVSLTQEEL-----DSGLDELSVR-SQDTTVLETLSNDFSMDNISDSGASN 596
+++ S S N + Q + S DE SQ + E ++ +D AS
Sbjct: 1512 SVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASG 1571
Query: 597 ETTNALQENSLADFSLPQTPQTDNPSEGRGEGVSKSFSDHGFYSPSSTLGDSPLVDDPLE 656
+ N L + S + ++ E +G+G + SST ++
Sbjct: 1572 SEDDEFIRNQLKEIS--SSTESQKKEETKGKGKITAGKHRRLTRKSST---------SID 1620
Query: 657 YQAGLLVQNAIQQAIAEQVDKAVSKTSRDGAEQQGPEATVEEA----------------- 699
AG +++ E D++ R+ Q+ E V
Sbjct: 1621 EDAGR--RHSWHDEDDEAFDESPELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIAD 1678
Query: 700 EAAAFGSEKPQSMF--EPPQV------SSPVQEKR----------DVLPKILPAEDRALR 741
+ +A S+K S++ E P++ SP R P P +L
Sbjct: 1679 KYSAESSQKKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLD 1738
Query: 742 ERGPPQPLPAVQPSGPINMEETRPEGSY---FSKYSEAAELRSTASLLATQESDVMVGPF 798
E P S RP G SE ELR LL QE +
Sbjct: 1739 EDSDSSPSHKKGESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQ 1798
Query: 799 KLRSRKQRTLSMIEEEIRAAQERE------------------EELKRQRQVLQSTQSPRT 840
+ +S +++ ++E+RA + RE EEL++ ++ + +S +
Sbjct: 1799 QRKSSSKKS-KKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCS 1857
Query: 841 KNAPSLPS-RTCYKTAPGKIEKV----KPPPSPTTEGPSLQPDLAPEEAAGTQRPKNLMQ 895
+ +PS+ S ++ +P KI +V K P + + P+ + + +E G+Q+ +
Sbjct: 1858 EYSPSIESDPEGFEISPEKIIEVQKVYKLPTAVSLYSPTDEQSIMQKE--GSQKALKSAE 1915
Query: 896 TLMED--YETHKSK 907
+ E+ ++THK K
Sbjct: 1916 EMYEEMMHKTHKYK 1929
Score = 32.0 bits (71), Expect = 2.8
Identities = 55/270 (20%), Positives = 106/270 (39%), Gaps = 47/270 (17%)
Query: 583 DFSMDNISDSG---ASNETTNALQENSLADFSLPQTPQT------DNPSEGRGEGVSKSF 633
+ M++++DS + E +++L +S + P + + +PS +GE +
Sbjct: 1698 ELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRK 1757
Query: 634 SDHGFYSPSSTLGDSPLVDDPLEYQAGLLVQNAIQQAIAEQVDKAVSKTSRDGAEQQGPE 693
+ H + P + ++ L + LL + Q+ I +Q K+ SK S+ ++ +
Sbjct: 1758 ARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQ 1817
Query: 694 ATVEEAEAAAFGSEKPQSMFEPPQVSSPVQEKRDVLPKILPAEDRALRERGPPQPLPAVQ 753
E + P S P + +SP +E R AE L + P++
Sbjct: 1818 RRRERPKT-------PPSNLSPIEDASPTEELRQA------AEMEELHRSSCSEYSPSI- 1863
Query: 754 PSGPINMEETRPEGSYFS-----KYSEAAELRSTASLLA-TQESDVMVGPFKLRSRKQRT 807
E+ PEG S + + +L + SL + T E +M ++ K
Sbjct: 1864 --------ESDPEGFEISPEKIIEVQKVYKLPTAVSLYSPTDEQSIMQKEGSQKALKSAE 1915
Query: 808 LSMIEEEIR---------AAQEREEELKRQ 828
M EE + AA ER+E +++
Sbjct: 1916 -EMYEEMMHKTHKYKAFPAANERDEVFEKE 1944
Score = 30.8 bits (68), Expect = 6.3
Identities = 29/122 (23%), Positives = 60/122 (49%), Gaps = 24/122 (19%)
Query: 275 EDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAKWWNPP 334
EDK+ +L + E+E + K++ ELE ER+E+ R +
Sbjct: 3207 EDKQQQQL----DLERELLELEKIKQQRFAEELEWERQEIQRFRE--------------- 3247
Query: 335 QEKT-IEEQLDE-EHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQLCTAPASSH 392
QEK ++++L+E + ++ H +++ +ER+AQ +++++ QQQ Q+ H
Sbjct: 3248 QEKIMVQKKLEELQSMKQHLLFQQEEERQAQ---FMMRQETLAQQQLQLEQIQQLQQQLH 3304
Query: 393 ER 394
++
Sbjct: 3305 QQ 3306
Score = 30.4 bits (67), Expect = 8.2
Identities = 63/309 (20%), Positives = 111/309 (35%), Gaps = 50/309 (16%)
Query: 614 QTPQTDNPSEGRGEGVSKSFSDHGFYSPSSTLGDSPLVDDPLEYQA-------------- 659
Q+ + +P G+SKS + F S G SP E ++
Sbjct: 95 QSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMP 154
Query: 660 GLLVQNAIQQAIAEQVDKAVSKTSRDGAEQQGPEATVEEAEAAAFGSEKPQSMFEPPQVS 719
G L + A++ V+K + + E T ++ + KP+ + +PP
Sbjct: 155 GFLSEVNALSAVSSVVNK-FNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQ 213
Query: 720 SPVQEKRDVLPKILPAEDRALRERGPPQPLPAVQPSG----------PINMEETRPEGSY 769
P + +PK L++ G P+ + + QP PI P+ +
Sbjct: 214 QPPKP----IPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDH 269
Query: 770 FSKYSEAAELRSTASLLATQESDVMVGPFKLRSRKQRTLSMIEEEIRAAQEREEELKRQR 829
L+ AS T+++D++ G S + I++ ++ +
Sbjct: 270 AK-----LPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKS 324
Query: 830 QVLQSTQSPRTKNAPSLPSRTCYKTA--PGKIEKVKPPPSP--TTEGPS--LQPDLAPEE 883
Q P P+ PS A PG VKPP P TT+ P+ L P P +
Sbjct: 325 Q-------PGPAKPPAQPSGLTKPLAQQPGT---VKPPVQPPGTTKPPAQPLGPAKPPAQ 374
Query: 884 AAGTQRPKN 892
G+++P +
Sbjct: 375 QTGSEKPSS 383
>gi|29826319 adducin 1 (alpha) isoform a [Homo sapiens]
Length = 737
Score = 46.6 bits (109), Expect = 1e-04
Identities = 63/275 (22%), Positives = 109/275 (39%), Gaps = 30/275 (10%)
Query: 241 SPSSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRP 300
SP S T + + DG T T+ L + K + + E+ I+ P
Sbjct: 465 SPKSKT--KWTKEDGHRTSTSAVPNLFVPLNT---NPKEVQEMRNKIREQNLQDIKTAGP 519
Query: 301 SEEMLELEKERRELIRSQAVKKNPGIAAKWWNP--------PQEKTIEEQLDEEHLESHK 352
++L R L++ + V + I K + P P T L + LE ++
Sbjct: 520 QSQVLCGVVMDRSLVQGELVTASKAIIEKEYQPHVIVSTTGPNPFTT---LTDRELEEYR 576
Query: 353 KYKERKERRAQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQI-- 410
+ ERK++ +++ L + +Q+++ PP Q PA H S K +ED+V E
Sbjct: 577 REVERKQKGSEEN---LDEAREQKEKSPPDQ----PAVPHPPPSTPIKLEEDLVPEPTTG 629
Query: 411 -DFSAARKQFQLMENSRQAVAKGQSTPRLFSIKPFYRPLGSVNSDKPLTNPRPPSVGGPP 469
D AA + L + S ++ P L + +RP + + P
Sbjct: 630 DDSDAATFKPTLPDLSPDEPSEALGFPMLEKEEEAHRPPSPTEAPTEASPEPAPDPAPVA 689
Query: 470 EDSGASAAKGQKSPGALETPSAAGSQGNTASQGKE 504
E++ SA + GA P + GS G + S+ K+
Sbjct: 690 EEAAPSAVE----EGAAADPGSDGSPGKSPSKKKK 720
Score = 32.0 bits (71), Expect = 2.8
Identities = 24/103 (23%), Positives = 43/103 (41%), Gaps = 3/103 (2%)
Query: 656 EYQAGLLVQNAIQQAIAEQVDKAVSKTSRD-GAEQQGPEATVEEAEAAAFGSEKPQSMFE 714
EYQ ++V D+ + + R+ +Q+G E ++EA S Q
Sbjct: 549 EYQPHVIVSTTGPNPFTTLTDRELEEYRREVERKQKGSEENLDEAREQKEKSPPDQPAVP 608
Query: 715 PPQVSSPVQEKRDVLPKILPAEDRALRERGPPQPLPAVQPSGP 757
P S+P++ + D++P+ +D P LP + P P
Sbjct: 609 HPPPSTPIKLEEDLVPEPTTGDDSDAATFKP--TLPDLSPDEP 649
>gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo
sapiens]
Length = 1297
Score = 46.2 bits (108), Expect = 1e-04
Identities = 57/277 (20%), Positives = 113/277 (40%), Gaps = 35/277 (12%)
Query: 184 HEATQPEPTERTASRQAPPHIELSNSSPDPMAEAE-RTNGHSPSQPRDALGDSLQVPVSP 242
H + +P ER Q HI+ + E E +G + + G+ + P
Sbjct: 286 HPFIRDQPNERQVRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLP 345
Query: 243 SSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSE 302
+T R +F L + + E A + + E++EH+++ R+ R
Sbjct: 346 GESTLRR------DFLRLQLANKERSE--ALRRQQLEQQQRENEEHKRQLLAERQKR--- 394
Query: 303 EMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKE--R 360
+E +KE+R + Q + EK + +Q + E +++ R+E R
Sbjct: 395 --IEEQKEQRRRLEEQQRR--------------EKELRKQQEREQRRHYEEQMRREEERR 438
Query: 361 RAQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQ 420
RA+ EQ +++QL+++Q+Q HE+A +++ ++ + EQ ++Q +
Sbjct: 439 RAEHEQEYIRRQLEEEQRQLE---ILQQQLLHEQALLLEYKRKQL-EEQRQAERLQRQLK 494
Query: 421 LMENSRQAVAKGQSTPRLFSIKPFYR-PLGSVNSDKP 456
+ ++ + R KP Y G S+KP
Sbjct: 495 QERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKP 531
>gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo
sapiens]
Length = 1305
Score = 46.2 bits (108), Expect = 1e-04
Identities = 57/277 (20%), Positives = 113/277 (40%), Gaps = 35/277 (12%)
Query: 184 HEATQPEPTERTASRQAPPHIELSNSSPDPMAEAE-RTNGHSPSQPRDALGDSLQVPVSP 242
H + +P ER Q HI+ + E E +G + + G+ + P
Sbjct: 286 HPFIRDQPNERQVRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLP 345
Query: 243 SSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSE 302
+T R +F L + + E A + + E++EH+++ R+ R
Sbjct: 346 GESTLRR------DFLRLQLANKERSE--ALRRQQLEQQQRENEEHKRQLLAERQKR--- 394
Query: 303 EMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKE--R 360
+E +KE+R + Q + EK + +Q + E +++ R+E R
Sbjct: 395 --IEEQKEQRRRLEEQQRR--------------EKELRKQQEREQRRHYEEQMRREEERR 438
Query: 361 RAQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQ 420
RA+ EQ +++QL+++Q+Q HE+A +++ ++ + EQ ++Q +
Sbjct: 439 RAEHEQEYIRRQLEEEQRQLE---ILQQQLLHEQALLLEYKRKQL-EEQRQAERLQRQLK 494
Query: 421 LMENSRQAVAKGQSTPRLFSIKPFYR-PLGSVNSDKP 456
+ ++ + R KP Y G S+KP
Sbjct: 495 QERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKP 531
>gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo
sapiens]
Length = 1352
Score = 46.2 bits (108), Expect = 1e-04
Identities = 57/277 (20%), Positives = 113/277 (40%), Gaps = 35/277 (12%)
Query: 184 HEATQPEPTERTASRQAPPHIELSNSSPDPMAEAE-RTNGHSPSQPRDALGDSLQVPVSP 242
H + +P ER Q HI+ + E E +G + + G+ + P
Sbjct: 286 HPFIRDQPNERQVRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLP 345
Query: 243 SSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSE 302
+T R +F L + + E A + + E++EH+++ R+ R
Sbjct: 346 GESTLRR------DFLRLQLANKERSE--ALRRQQLEQQQRENEEHKRQLLAERQKR--- 394
Query: 303 EMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKE--R 360
+E +KE+R + Q + EK + +Q + E +++ R+E R
Sbjct: 395 --IEEQKEQRRRLEEQQRR--------------EKELRKQQEREQRRHYEEQMRREEERR 438
Query: 361 RAQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQ 420
RA+ EQ +++QL+++Q+Q HE+A +++ ++ + EQ ++Q +
Sbjct: 439 RAEHEQEYIRRQLEEEQRQLE---ILQQQLLHEQALLLEYKRKQL-EEQRQAERLQRQLK 494
Query: 421 LMENSRQAVAKGQSTPRLFSIKPFYR-PLGSVNSDKP 456
+ ++ + R KP Y G S+KP
Sbjct: 495 QERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKP 531
>gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo
sapiens]
Length = 1360
Score = 46.2 bits (108), Expect = 1e-04
Identities = 57/277 (20%), Positives = 113/277 (40%), Gaps = 35/277 (12%)
Query: 184 HEATQPEPTERTASRQAPPHIELSNSSPDPMAEAE-RTNGHSPSQPRDALGDSLQVPVSP 242
H + +P ER Q HI+ + E E +G + + G+ + P
Sbjct: 286 HPFIRDQPNERQVRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLP 345
Query: 243 SSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSE 302
+T R +F L + + E A + + E++EH+++ R+ R
Sbjct: 346 GESTLRR------DFLRLQLANKERSE--ALRRQQLEQQQRENEEHKRQLLAERQKR--- 394
Query: 303 EMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKE--R 360
+E +KE+R + Q + EK + +Q + E +++ R+E R
Sbjct: 395 --IEEQKEQRRRLEEQQRR--------------EKELRKQQEREQRRHYEEQMRREEERR 438
Query: 361 RAQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQ 420
RA+ EQ +++QL+++Q+Q HE+A +++ ++ + EQ ++Q +
Sbjct: 439 RAEHEQEYIRRQLEEEQRQLE---ILQQQLLHEQALLLEYKRKQL-EEQRQAERLQRQLK 494
Query: 421 LMENSRQAVAKGQSTPRLFSIKPFYR-PLGSVNSDKP 456
+ ++ + R KP Y G S+KP
Sbjct: 495 QERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKP 531
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 45.8 bits (107), Expect = 2e-04
Identities = 34/116 (29%), Positives = 60/116 (51%), Gaps = 9/116 (7%)
Query: 264 KEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKN 323
+ AKF L + +++ +E +EQ +K+R EE + ++ER +R Q K
Sbjct: 256 ERAKFLLPQVQTNTLQEEMWRQEEELREQE--KKIRKQEEKMWRQEER---LREQEGKMR 310
Query: 324 PGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQ 379
W QEK + EQ ++E E K+ +E+KE R Q+EQ+ Q++ +Q++
Sbjct: 311 EQEEKMW---RQEKRLREQ-EKELREQEKELREQKELREQEEQMQEQEEKMWEQEE 362
Score = 38.9 bits (89), Expect = 0.023
Identities = 33/140 (23%), Positives = 73/140 (52%), Gaps = 21/140 (15%)
Query: 263 KKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCI----RKVRPSEEMLELEKE--RRELIR 316
++E +++ + E K+ KL+E ++ ++++ I K+R EEM EK+ R+E +R
Sbjct: 483 QEEKEWQQQRLPEQKE--KLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMR 540
Query: 317 SQA------VKKNPGIAAKWWNPPQ--EKTIEEQL-----DEEHLESHKKYKERKERRAQ 363
Q +K K W+ + EK +EQ EE + ++ +ER+++ +
Sbjct: 541 EQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMRE 600
Query: 364 QEQLLLQKQLQQQQQQPPSQ 383
+E+++ +++ + Q+Q+ Q
Sbjct: 601 EEEMMREQEEKMQEQEEKMQ 620
Score = 38.9 bits (89), Expect = 0.023
Identities = 34/124 (27%), Positives = 61/124 (49%), Gaps = 17/124 (13%)
Query: 263 KKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRE---LIRSQA 319
+K + E + + ++K K E EK+ + K+R E M E EK+ RE ++R Q
Sbjct: 677 EKMQEQEEKIWEQEKMEKKT---QEQEKKTWDQEKMREEESMREREKKMREEEEMMREQE 733
Query: 320 VKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQ 379
K QE+ ++EQ +EE E +K E++E+ +Q++L QK+ + ++
Sbjct: 734 EKMQE----------QEEKMQEQ-EEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEK 782
Query: 380 PPSQ 383
Q
Sbjct: 783 MQEQ 786
Score = 37.4 bits (85), Expect = 0.067
Identities = 36/133 (27%), Positives = 65/133 (48%), Gaps = 19/133 (14%)
Query: 275 EDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRE---LIRSQAVKKNPGIAAKWW 331
E++ K E ++ +Q K+R E M E EK+ RE ++R Q K
Sbjct: 564 EERMEKKTQEQEKKTWDQE--EKMREEERMREREKKMREEEEMMREQEEKMQE------- 614
Query: 332 NPPQEKTIEEQLDEEHLESHKKYKERKERR-AQQEQLLLQKQLQQQQQQPPSQLCTAPAS 390
QE+ ++EQ +E+ E +K +E++E+ Q+E++ Q++ +QQ+ P Q
Sbjct: 615 ---QEEKMQEQ-EEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQ--KEKLW 668
Query: 391 SHERASMIDKAKE 403
HE+ +K +E
Sbjct: 669 EHEKMQEQEKMQE 681
Score = 35.4 bits (80), Expect = 0.25
Identities = 26/112 (23%), Positives = 56/112 (50%), Gaps = 14/112 (12%)
Query: 277 KKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEK-ERRELIRSQAVKKNPGIAAKWWNPPQ 335
++ K++E +E EQ R E++ E EK + +E ++ Q K W
Sbjct: 642 EQEEKMWEQEEKMWEQQ--RLPEQKEKLWEHEKMQEQEKMQEQEEKI-------WEQEKM 692
Query: 336 EKTIEEQ----LDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQ 383
EK +EQ D+E + + +ER+++ ++E+++ +++ + Q+Q+ Q
Sbjct: 693 EKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQ 744
Score = 34.3 bits (77), Expect = 0.57
Identities = 33/131 (25%), Positives = 62/131 (47%), Gaps = 9/131 (6%)
Query: 253 RDGEFTLTTLKKEAKF--ELRAFHED--KKPSKLFEDDEHEKEQYCIRKVRPSEEMLELE 308
R+ E L +KE + ELR E ++ K++E +E +EQ + R E + E E
Sbjct: 324 REQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQE-EKMWRQEERLWEQE 382
Query: 309 KERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLL 368
K+ RE Q K W + + EE++ E+ + K R+E++ Q+++
Sbjct: 383 KQMRE----QEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKK 438
Query: 369 LQKQLQQQQQQ 379
+ Q ++ Q++
Sbjct: 439 TRDQEEKMQEE 449
Score = 34.3 bits (77), Expect = 0.57
Identities = 25/96 (26%), Positives = 48/96 (50%), Gaps = 15/96 (15%)
Query: 284 EDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQL 343
ED E+E+ K+R E+ + ++ER E KK K W+ ++ EE++
Sbjct: 543 EDQMWEQEE----KMRDQEQKMWDQEERME-------KKTQEQEKKTWDQEEKMREEERM 591
Query: 344 DEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQ 379
E KK +E +E +QE+ + +++ + Q+Q+
Sbjct: 592 RER----EKKMREEEEMMREQEEKMQEQEEKMQEQE 623
Score = 33.9 bits (76), Expect = 0.74
Identities = 30/123 (24%), Positives = 64/123 (52%), Gaps = 13/123 (10%)
Query: 265 EAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVK--- 321
E K +L + ++ K++E +E ++Q K+R EE + ++E+ +R Q K
Sbjct: 772 EQKEKLWEHEKMQEQEKIWEQEEKMRDQE--EKMRGQEEKMRGQEEK---MRGQEEKMWG 826
Query: 322 ---KNPGIAAKWWNPPQEKTIEEQLDEEHLESHK-KYKERKER-RAQQEQLLLQKQLQQQ 376
K G K W ++ +E+ EE ++ + K +E++E+ R Q+E++ Q++ +
Sbjct: 827 QEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRG 886
Query: 377 QQQ 379
Q++
Sbjct: 887 QEE 889
Score = 32.7 bits (73), Expect = 1.6
Identities = 22/97 (22%), Positives = 50/97 (51%), Gaps = 2/97 (2%)
Query: 287 EHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEE 346
E EK + K+R ++M E EK+ R+ + + +++ I + +E+ + +E+
Sbjct: 415 EQEKMWEQVEKMREEKKMQEQEKKTRD--QEEKMQEEERIREREKKMREEEETMREQEEK 472
Query: 347 HLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQ 383
+ + E++E+ QQ++L QK+ +Q++ Q
Sbjct: 473 MQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQ 509
Score = 31.2 bits (69), Expect = 4.8
Identities = 26/111 (23%), Positives = 59/111 (53%), Gaps = 8/111 (7%)
Query: 269 ELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAA 328
E R ++K ++ + E +K Q +K R EE ++ E+ RE R + +++
Sbjct: 410 EERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIRE--REKKMREEEETMR 467
Query: 329 KWWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQ 379
+ QE+ +++Q +E E +K +++ Q+E+L Q+++Q+Q+++
Sbjct: 468 E-----QEEKMQKQ-EENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEK 512
Score = 30.4 bits (67), Expect = 8.2
Identities = 23/103 (22%), Positives = 50/103 (48%), Gaps = 5/103 (4%)
Query: 286 DEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEE---- 341
D+ E+ ++R EE + +++ E + +K K +EK EE
Sbjct: 394 DQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIR 453
Query: 342 QLDEEHLESHKKYKERKER-RAQQEQLLLQKQLQQQQQQPPSQ 383
+ +++ E + +E++E+ + Q+E + Q++ + QQQ+ P Q
Sbjct: 454 EREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQ 496
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 45.4 bits (106), Expect = 2e-04
Identities = 69/321 (21%), Positives = 122/321 (38%), Gaps = 57/321 (17%)
Query: 189 PEPTERTASRQAPPHIELSNSSPDPMAEAERTNGHSPSQPRDALGDSLQVPVSPSSTTSS 248
P P+ + APP E P AE S P A PV+PS +
Sbjct: 545 PAPSPAPSPTPAPPQKE------QPPAETPTDAAVLTSPPAPA------PPVTPSKPMAG 592
Query: 249 RCSSRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELE 308
+ L +++A+ + E +E E+ R R EE L E
Sbjct: 593 TTDREEATRLLAEKRRQAREQR-------------EREEQERRLQAERDKRMREEQLARE 639
Query: 309 KERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKER-RAQQEQL 367
E R ++A ++ A +EK EQ ++E L+ K+ E + R A++++L
Sbjct: 640 AEARAEREAEARRREEQEA-------REKAQAEQEEQERLQKQKEEAEARSREEAERQRL 692
Query: 368 LLQKQLQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQ 427
+K QQQ+Q+ ER +++ + T + + S +++ ++S++
Sbjct: 693 EREKHFQQQEQE-----------RQERRKRLEEIMKR--TRKSEVSETKQK----QDSKE 735
Query: 428 AVAKGQSTPRLFSIKPFYRPLGSVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKSPGALE 487
A A G S + +++ L K P+ P P ++ AS G +
Sbjct: 736 ANANGSSPEPVKAVEARSPGLQKEAVQKEEPIPQEPQWSLPSKELPASLVNGLQ------ 789
Query: 488 TPSAAGSQGNTASQGKEGPYS 508
P A + ++ G G S
Sbjct: 790 -PLPAHQENGFSTNGPSGDKS 809
Score = 40.0 bits (92), Expect = 0.010
Identities = 48/213 (22%), Positives = 87/213 (40%), Gaps = 23/213 (10%)
Query: 175 LVGGLSPPVHEATQPEPTERTASRQAPPHIELSNSSPD------PMAEAERTNGHSPSQP 228
L G P V T PEP +PP +S PD P + ++ P +P
Sbjct: 9 LGAGAPPAVVARTPPEPRPSPEGDPSPPPPPMSALVPDTPPDTPPAMKNATSSKQLPLEP 68
Query: 229 RDALGDSLQVPVSPSSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEH 288
G P P + S + G ++A+ R+ P+ + D
Sbjct: 69 ESPSGQVGPRPAPPQEESPSSEAKSRGPTPPAMGPRDARPPRRS--SQPSPTAVPASDSP 126
Query: 289 EKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAK--WWNPPQEKTIEEQLDEE 346
+Q +V+ + E +L KERRE ++ +AAK W +EK + L E+
Sbjct: 127 PTKQ----EVKKAGERHKLAKERRE-------ERAKYLAAKKAVWLEKEEKA--KALREK 173
Query: 347 HLESHKKYKERKERRAQQEQLLLQKQLQQQQQQ 379
L+ ++ E + +A+Q + L+++ +Q+ ++
Sbjct: 174 QLQERRRRLEEQRLKAEQRRAALEERQRQKLEK 206
Score = 31.2 bits (69), Expect = 4.8
Identities = 33/147 (22%), Positives = 53/147 (36%), Gaps = 22/147 (14%)
Query: 715 PPQVSSPVQEKRD---VLPKILPAEDRALRERGPPQPLPAVQPSGPINMEETRPEGSYFS 771
PPQ SP E + P + P + R R P P P +E + G
Sbjct: 81 PPQEESPSSEAKSRGPTPPAMGPRDARPPRRSSQPSPTAVPASDSPPTKQEVKKAGERHK 140
Query: 772 KYSEAAELRSTASLLATQESDVMVGPFKLRSRKQRTLSMIEEEIRAAQEREEELKRQRQV 831
E E R A LA +++ +E+E +A RE++L+ +R+
Sbjct: 141 LAKERREER--AKYLAAKKA-----------------VWLEKEEKAKALREKQLQERRRR 181
Query: 832 LQSTQSPRTKNAPSLPSRTCYKTAPGK 858
L+ + + +L R K K
Sbjct: 182 LEEQRLKAEQRRAALEERQRQKLEKNK 208
Score = 30.4 bits (67), Expect = 8.2
Identities = 16/47 (34%), Positives = 19/47 (40%)
Query: 8 AAARLPPESPGPPESPGPPEREAAAARRWTGAEPQDCAPGSGRPEKP 54
AA P SP P +P PP++E A T A P P P
Sbjct: 540 AAPASPAPSPAPSPTPAPPQKEQPPAETPTDAAVLTSPPAPAPPVTP 586
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 45.1 bits (105), Expect = 3e-04
Identities = 41/163 (25%), Positives = 80/163 (49%), Gaps = 24/163 (14%)
Query: 284 EDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAKWWNPPQE--KTIEE 341
E++E ++++ +R++ EE E+ERR+ + + ++K AAKW +E + +EE
Sbjct: 803 EEEERQQQEEALRRL---EERRREEEERRK--QEELLRKQEEEAAKWAREEEEAQRRLEE 857
Query: 342 ---QLDEE-----HLESHKKYKE---------RKERRAQQEQLLLQKQLQQQQQQPPSQL 384
+++EE H E +K KE ++R+ QQE L +Q QQQQQ +L
Sbjct: 858 NRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKL 917
Query: 385 CTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQ 427
++ + + +++ + +I ++ QL E R+
Sbjct: 918 PSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRR 960
Score = 37.7 bits (86), Expect = 0.051
Identities = 25/130 (19%), Positives = 61/130 (46%), Gaps = 4/130 (3%)
Query: 302 EEMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKERR 361
E++ +LEK + + + ++ + AK +E+ +E+L + E ++ +E + +R
Sbjct: 718 EQLQQLEKAKAAKLEQE--RREAEMRAK--REEEERKRQEELRRQQEEILRRQQEEERKR 773
Query: 362 AQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQL 421
++E+L +KQ + ++Q ++ E ++A + + + RKQ +L
Sbjct: 774 REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEEL 833
Query: 422 MENSRQAVAK 431
+ + AK
Sbjct: 834 LRKQEEEAAK 843
Score = 35.4 bits (80), Expect = 0.25
Identities = 28/121 (23%), Positives = 59/121 (48%), Gaps = 11/121 (9%)
Query: 264 KEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKN 323
+E LR E++K +L E ++++ +R+ + +E L +++++ + Q +
Sbjct: 863 EEEAARLRHEEEERKRKEL----EVQRQKELMRQRQQQQEALRRLQQQQQ--QQQLAQMK 916
Query: 324 PGIAAKWWNPPQEKTIEEQL-----DEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQ 378
++ W + Q + + LE ++ + R+E+R QQ +L+ Q QQQQQ
Sbjct: 917 LPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQ 976
Query: 379 Q 379
Q
Sbjct: 977 Q 977
Score = 32.3 bits (72), Expect = 2.2
Identities = 16/38 (42%), Positives = 23/38 (60%)
Query: 346 EHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQ 383
E E K++ ER+ ++ +Q Q+ QQQQQQPP Q
Sbjct: 1177 EAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQ 1214
Score = 31.6 bits (70), Expect = 3.7
Identities = 24/117 (20%), Positives = 55/117 (47%), Gaps = 13/117 (11%)
Query: 275 EDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAV-----KKNPGIAAK 329
E K +KL E + E E R+ + EL +++ E++R Q ++ +A +
Sbjct: 724 EKAKAAKL-EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARR 782
Query: 330 WWNPPQEKTIEEQL-------DEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQ 379
+ E+++ +EE + + + +ERR ++E+ Q++L ++Q++
Sbjct: 783 KQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEE 839
Score = 31.2 bits (69), Expect = 4.8
Identities = 17/43 (39%), Positives = 25/43 (58%), Gaps = 3/43 (6%)
Query: 341 EQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQ 383
++ ++ LE K K ++R+ QQ L Q+Q QQ QQPP Q
Sbjct: 1179 KEFAKQFLERRAKQKANQQRQQQQ---LPQQQQQQPPQQPPQQ 1218
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 45.1 bits (105), Expect = 3e-04
Identities = 41/163 (25%), Positives = 80/163 (49%), Gaps = 24/163 (14%)
Query: 284 EDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAKWWNPPQE--KTIEE 341
E++E ++++ +R++ EE E+ERR+ + + ++K AAKW +E + +EE
Sbjct: 830 EEEERQQQEEALRRL---EERRREEEERRK--QEELLRKQEEEAAKWAREEEEAQRRLEE 884
Query: 342 ---QLDEE-----HLESHKKYKE---------RKERRAQQEQLLLQKQLQQQQQQPPSQL 384
+++EE H E +K KE ++R+ QQE L +Q QQQQQ +L
Sbjct: 885 NRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKL 944
Query: 385 CTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQ 427
++ + + +++ + +I ++ QL E R+
Sbjct: 945 PSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRR 987
Score = 37.7 bits (86), Expect = 0.051
Identities = 25/130 (19%), Positives = 61/130 (46%), Gaps = 4/130 (3%)
Query: 302 EEMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKERR 361
E++ +LEK + + + ++ + AK +E+ +E+L + E ++ +E + +R
Sbjct: 745 EQLQQLEKAKAAKLEQE--RREAEMRAK--REEEERKRQEELRRQQEEILRRQQEEERKR 800
Query: 362 AQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQL 421
++E+L +KQ + ++Q ++ E ++A + + + RKQ +L
Sbjct: 801 REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEEL 860
Query: 422 MENSRQAVAK 431
+ + AK
Sbjct: 861 LRKQEEEAAK 870
Score = 35.4 bits (80), Expect = 0.25
Identities = 28/121 (23%), Positives = 59/121 (48%), Gaps = 11/121 (9%)
Query: 264 KEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKN 323
+E LR E++K +L E ++++ +R+ + +E L +++++ + Q +
Sbjct: 890 EEEAARLRHEEEERKRKEL----EVQRQKELMRQRQQQQEALRRLQQQQQ--QQQLAQMK 943
Query: 324 PGIAAKWWNPPQEKTIEEQL-----DEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQ 378
++ W + Q + + LE ++ + R+E+R QQ +L+ Q QQQQQ
Sbjct: 944 LPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQ 1003
Query: 379 Q 379
Q
Sbjct: 1004 Q 1004
Score = 32.3 bits (72), Expect = 2.2
Identities = 16/38 (42%), Positives = 23/38 (60%)
Query: 346 EHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQ 383
E E K++ ER+ ++ +Q Q+ QQQQQQPP Q
Sbjct: 1204 EAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQ 1241
Score = 31.6 bits (70), Expect = 3.7
Identities = 24/117 (20%), Positives = 55/117 (47%), Gaps = 13/117 (11%)
Query: 275 EDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAV-----KKNPGIAAK 329
E K +KL E + E E R+ + EL +++ E++R Q ++ +A +
Sbjct: 751 EKAKAAKL-EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARR 809
Query: 330 WWNPPQEKTIEEQL-------DEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQ 379
+ E+++ +EE + + + +ERR ++E+ Q++L ++Q++
Sbjct: 810 KQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEE 866
Score = 31.2 bits (69), Expect = 4.8
Identities = 17/43 (39%), Positives = 25/43 (58%), Gaps = 3/43 (6%)
Query: 341 EQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQ 383
++ ++ LE K K ++R+ QQ L Q+Q QQ QQPP Q
Sbjct: 1206 KEFAKQFLERRAKQKANQQRQQQQ---LPQQQQQQPPQQPPQQ 1245
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 45.1 bits (105), Expect = 3e-04
Identities = 41/163 (25%), Positives = 80/163 (49%), Gaps = 24/163 (14%)
Query: 284 EDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAKWWNPPQE--KTIEE 341
E++E ++++ +R++ EE E+ERR+ + + ++K AAKW +E + +EE
Sbjct: 809 EEEERQQQEEALRRL---EERRREEEERRK--QEELLRKQEEEAAKWAREEEEAQRRLEE 863
Query: 342 ---QLDEE-----HLESHKKYKE---------RKERRAQQEQLLLQKQLQQQQQQPPSQL 384
+++EE H E +K KE ++R+ QQE L +Q QQQQQ +L
Sbjct: 864 NRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKL 923
Query: 385 CTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQ 427
++ + + +++ + +I ++ QL E R+
Sbjct: 924 PSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRR 966
Score = 37.7 bits (86), Expect = 0.051
Identities = 25/130 (19%), Positives = 61/130 (46%), Gaps = 4/130 (3%)
Query: 302 EEMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKERR 361
E++ +LEK + + + ++ + AK +E+ +E+L + E ++ +E + +R
Sbjct: 724 EQLQQLEKAKAAKLEQE--RREAEMRAK--REEEERKRQEELRRQQEEILRRQQEEERKR 779
Query: 362 AQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQL 421
++E+L +KQ + ++Q ++ E ++A + + + RKQ +L
Sbjct: 780 REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEEL 839
Query: 422 MENSRQAVAK 431
+ + AK
Sbjct: 840 LRKQEEEAAK 849
Score = 35.4 bits (80), Expect = 0.25
Identities = 28/121 (23%), Positives = 59/121 (48%), Gaps = 11/121 (9%)
Query: 264 KEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKN 323
+E LR E++K +L E ++++ +R+ + +E L +++++ + Q +
Sbjct: 869 EEEAARLRHEEEERKRKEL----EVQRQKELMRQRQQQQEALRRLQQQQQ--QQQLAQMK 922
Query: 324 PGIAAKWWNPPQEKTIEEQL-----DEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQ 378
++ W + Q + + LE ++ + R+E+R QQ +L+ Q QQQQQ
Sbjct: 923 LPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQ 982
Query: 379 Q 379
Q
Sbjct: 983 Q 983
Score = 32.3 bits (72), Expect = 2.2
Identities = 16/38 (42%), Positives = 23/38 (60%)
Query: 346 EHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQ 383
E E K++ ER+ ++ +Q Q+ QQQQQQPP Q
Sbjct: 1183 EAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQ 1220
Score = 31.6 bits (70), Expect = 3.7
Identities = 24/117 (20%), Positives = 55/117 (47%), Gaps = 13/117 (11%)
Query: 275 EDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAV-----KKNPGIAAK 329
E K +KL E + E E R+ + EL +++ E++R Q ++ +A +
Sbjct: 730 EKAKAAKL-EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARR 788
Query: 330 WWNPPQEKTIEEQL-------DEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQ 379
+ E+++ +EE + + + +ERR ++E+ Q++L ++Q++
Sbjct: 789 KQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEE 845
Score = 31.2 bits (69), Expect = 4.8
Identities = 17/43 (39%), Positives = 25/43 (58%), Gaps = 3/43 (6%)
Query: 341 EQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQ 383
++ ++ LE K K ++R+ QQ L Q+Q QQ QQPP Q
Sbjct: 1185 KEFAKQFLERRAKQKANQQRQQQQ---LPQQQQQQPPQQPPQQ 1224
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 45.1 bits (105), Expect = 3e-04
Identities = 41/163 (25%), Positives = 80/163 (49%), Gaps = 24/163 (14%)
Query: 284 EDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAKWWNPPQE--KTIEE 341
E++E ++++ +R++ EE E+ERR+ + + ++K AAKW +E + +EE
Sbjct: 809 EEEERQQQEEALRRL---EERRREEEERRK--QEELLRKQEEEAAKWAREEEEAQRRLEE 863
Query: 342 ---QLDEE-----HLESHKKYKE---------RKERRAQQEQLLLQKQLQQQQQQPPSQL 384
+++EE H E +K KE ++R+ QQE L +Q QQQQQ +L
Sbjct: 864 NRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKL 923
Query: 385 CTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQ 427
++ + + +++ + +I ++ QL E R+
Sbjct: 924 PSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRR 966
Score = 37.7 bits (86), Expect = 0.051
Identities = 25/130 (19%), Positives = 61/130 (46%), Gaps = 4/130 (3%)
Query: 302 EEMLELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKERR 361
E++ +LEK + + + ++ + AK +E+ +E+L + E ++ +E + +R
Sbjct: 724 EQLQQLEKAKAAKLEQE--RREAEMRAK--REEEERKRQEELRRQQEEILRRQQEEERKR 779
Query: 362 AQQEQLLLQKQLQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQL 421
++E+L +KQ + ++Q ++ E ++A + + + RKQ +L
Sbjct: 780 REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEEL 839
Query: 422 MENSRQAVAK 431
+ + AK
Sbjct: 840 LRKQEEEAAK 849
Score = 35.4 bits (80), Expect = 0.25
Identities = 28/121 (23%), Positives = 59/121 (48%), Gaps = 11/121 (9%)
Query: 264 KEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKN 323
+E LR E++K +L E ++++ +R+ + +E L +++++ + Q +
Sbjct: 869 EEEAARLRHEEEERKRKEL----EVQRQKELMRQRQQQQEALRRLQQQQQ--QQQLAQMK 922
Query: 324 PGIAAKWWNPPQEKTIEEQL-----DEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQ 378
++ W + Q + + LE ++ + R+E+R QQ +L+ Q QQQQQ
Sbjct: 923 LPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQ 982
Query: 379 Q 379
Q
Sbjct: 983 Q 983
Score = 32.3 bits (72), Expect = 2.2
Identities = 16/38 (42%), Positives = 23/38 (60%)
Query: 346 EHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQ 383
E E K++ ER+ ++ +Q Q+ QQQQQQPP Q
Sbjct: 1183 EAKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQPPQQ 1220
Score = 31.6 bits (70), Expect = 3.7
Identities = 24/117 (20%), Positives = 55/117 (47%), Gaps = 13/117 (11%)
Query: 275 EDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAV-----KKNPGIAAK 329
E K +KL E + E E R+ + EL +++ E++R Q ++ +A +
Sbjct: 730 EKAKAAKL-EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARR 788
Query: 330 WWNPPQEKTIEEQL-------DEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQ 379
+ E+++ +EE + + + +ERR ++E+ Q++L ++Q++
Sbjct: 789 KQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEE 845
Score = 31.2 bits (69), Expect = 4.8
Identities = 17/43 (39%), Positives = 25/43 (58%), Gaps = 3/43 (6%)
Query: 341 EQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQ 383
++ ++ LE K K ++R+ QQ L Q+Q QQ QQPP Q
Sbjct: 1185 KEFAKQFLERRAKQKANQQRQQQQ---LPQQQQQQPPQQPPQQ 1224
>gi|21493022 A kinase (PRKA) anchor protein 12 isoform 1 [Homo
sapiens]
Length = 1782
Score = 45.1 bits (105), Expect = 3e-04
Identities = 65/315 (20%), Positives = 117/315 (37%), Gaps = 67/315 (21%)
Query: 619 DNPSEGRGEGVSKSFSDHGFYSPSSTLGDSPLVDDPLEYQAGLLVQNAIQQAIAEQVDKA 678
+ P + VSK S+ + ++ + D +E ++ + ++ + + EQV+
Sbjct: 870 EQPEQKAATEVSKELSESQVHMMAAAVADGTRAATIIEERSPSWISASVTEPL-EQVEAE 928
Query: 679 VSKTSRDGAEQQGPEATVEEAEAAAFGSEKPQSMFEPPQVSSPVQEKRDVLPKILPAEDR 738
+ + + E+ E EE EPP V+ P+ E R+ + +E
Sbjct: 929 AALLTEEVLER---EVIAEE---------------EPPTVTEPLPENREARGDTVVSEAE 970
Query: 739 ALRERGPPQPLPAVQPSGPINMEETRPEGSYFSKYSEAAELRSTASLL---------ATQ 789
P+ + A + +GP+ EE G+ S E E+ S S L AT
Sbjct: 971 LT-----PEAVTAAETAGPLGAEE----GTEASAAEETTEMVSAVSQLTDSPDTTEEATP 1021
Query: 790 ESDVMVGPFKLRSRKQRT---LSMIEEEI--------------------RAAQEREEE-- 824
+V G + +++RT L + E++ RA ER EE
Sbjct: 1022 VQEVEGGVPDIEEQERRTQEVLQAVAEKVKEESQLPGTGGPEDVLQPVQRAEAERPEEQA 1081
Query: 825 ----LKRQRQVLQSTQSPRTKNAPSLPSRTCYKTAPGKIEKVKPPPSPTTEGPSLQPDLA 880
LK++ V+ + K P + +T P EK P + + E L
Sbjct: 1082 EASGLKKETDVVLKVDAQEAKTEPFTQGKVVGQTTPESFEKA-PQVTESIESSELVTTCQ 1140
Query: 881 PEEAAGTQRPKNLMQ 895
E AG + + +M+
Sbjct: 1141 AETLAGVKSQEMVME 1155
>gi|21493024 A kinase (PRKA) anchor protein 12 isoform 2 [Homo
sapiens]
Length = 1684
Score = 45.1 bits (105), Expect = 3e-04
Identities = 65/315 (20%), Positives = 117/315 (37%), Gaps = 67/315 (21%)
Query: 619 DNPSEGRGEGVSKSFSDHGFYSPSSTLGDSPLVDDPLEYQAGLLVQNAIQQAIAEQVDKA 678
+ P + VSK S+ + ++ + D +E ++ + ++ + + EQV+
Sbjct: 772 EQPEQKAATEVSKELSESQVHMMAAAVADGTRAATIIEERSPSWISASVTEPL-EQVEAE 830
Query: 679 VSKTSRDGAEQQGPEATVEEAEAAAFGSEKPQSMFEPPQVSSPVQEKRDVLPKILPAEDR 738
+ + + E+ E EE EPP V+ P+ E R+ + +E
Sbjct: 831 AALLTEEVLER---EVIAEE---------------EPPTVTEPLPENREARGDTVVSEAE 872
Query: 739 ALRERGPPQPLPAVQPSGPINMEETRPEGSYFSKYSEAAELRSTASLL---------ATQ 789
P+ + A + +GP+ EE G+ S E E+ S S L AT
Sbjct: 873 LT-----PEAVTAAETAGPLGAEE----GTEASAAEETTEMVSAVSQLTDSPDTTEEATP 923
Query: 790 ESDVMVGPFKLRSRKQRT---LSMIEEEI--------------------RAAQEREEE-- 824
+V G + +++RT L + E++ RA ER EE
Sbjct: 924 VQEVEGGVPDIEEQERRTQEVLQAVAEKVKEESQLPGTGGPEDVLQPVQRAEAERPEEQA 983
Query: 825 ----LKRQRQVLQSTQSPRTKNAPSLPSRTCYKTAPGKIEKVKPPPSPTTEGPSLQPDLA 880
LK++ V+ + K P + +T P EK P + + E L
Sbjct: 984 EASGLKKETDVVLKVDAQEAKTEPFTQGKVVGQTTPESFEKA-PQVTESIESSELVTTCQ 1042
Query: 881 PEEAAGTQRPKNLMQ 895
E AG + + +M+
Sbjct: 1043 AETLAGVKSQEMVME 1057
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 45.1 bits (105), Expect = 3e-04
Identities = 82/433 (18%), Positives = 161/433 (37%), Gaps = 46/433 (10%)
Query: 470 EDSGASAAKGQKSPGALETPSAAGSQGNTASQGKEGPYSEPSKRGPLSKLWAEDGEFTSA 529
E+ A +G++ G E + G + + +E E + P+ + E S
Sbjct: 474 EEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKE------EAKSP 527
Query: 530 RAVLTVVKDDDHGILDQFSRSVNVSLTQEELDSGLDELSVRSQDTTVLETLSNDFSMDNI 589
+ K++ + S S +EE S + S ++ + +
Sbjct: 528 AEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEK---- 583
Query: 590 SDSGASNETTNALQENSLADFSLPQTPQTDNPSEGRGEGVSKSFSDHGFYSPSSTLGDSP 649
+ S A E + + S P + +P+E + ++ S SP SP
Sbjct: 584 AKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKA--KSP 641
Query: 650 LVDDPLEYQAGLLVQNAIQQAIAEQVDKAVSKTSRDGAEQQGPEATVEEAEAAAFGSEKP 709
++ + + ++ A+ +KA S AE + PE +A A EK
Sbjct: 642 TKEEAKSPEKA----KSPEKEEAKSPEKAKSPVK---AEAKSPEKAKSPVKAEAKSPEKA 694
Query: 710 QSMFE-----PPQVSSPVQEKRDVLPKILPAEDRALRERGPPQPLPAVQPSGPINMEETR 764
+S + P + SPV+E+ K A+ E P+ + P+ E
Sbjct: 695 KSPVKEEAKSPEKAKSPVKEEAKSPEK---AKSPVKEEAKTPE-----KAKSPVKEEAKS 746
Query: 765 PEGSYFSKYSEAAELRST-ASLLATQESDVMVGPFKLRSRKQRTLSMIEEEIRAAQEREE 823
PE + + ++ +++S A A +E+ F +++ S ++EE+++ ++ +
Sbjct: 747 PEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAK-----SPVKEEVKSPEKAKS 801
Query: 824 ELKR-----QRQVLQSTQSPRTKNAPSLPSRTCYKTAPGKIEKVKPPPSPTTEGPSLQPD 878
LK ++++ + + P K P K E+ K P +P TE + D
Sbjct: 802 PLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEE---KKD 858
Query: 879 LAPEEAAGTQRPK 891
EEA + PK
Sbjct: 859 SKKEEAPKKEAPK 871
Score = 38.9 bits (89), Expect = 0.023
Identities = 95/526 (18%), Positives = 177/526 (33%), Gaps = 56/526 (10%)
Query: 15 ESPGPP-ESPGPPEREAAAARRWTGAEPQDC-APGSGRPEKPPQLSEDDIWLKSEGDNYS 72
E+ PP E PE+EA + + P + +P + P ++ + K++
Sbjct: 500 ETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPE---KAKSPAKE 556
Query: 73 ATLLEPAASSLSPDHKNMEIEVSVAECKSVPGITSTPHPMD--HPSAFYSPPHNGLLTDH 130
P A S + EV E P P + P SP +
Sbjct: 557 EAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPA 616
Query: 131 HESLDNDVAREIRYLDEVLEANCCDSAVDGTYNGTSSPEPGAVVLVGGLSPPVHEATQPE 190
+ V E + EV + A T SPE +A PE
Sbjct: 617 EAK--SPVKEEAKSPAEVKSP---EKAKSPTKEEAKSPE---------------KAKSPE 656
Query: 191 PTERTASRQAPPHIELSNSSPDPMAEAERTNGHSPSQPRDALGDSLQVPVSPSSTTSSRC 250
E + +A ++ SP+ + SP + + + + + P S
Sbjct: 657 KEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEA 716
Query: 251 SS--------RDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVR--- 299
S ++ T K K E ++ + K P K D E K
Sbjct: 717 KSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARS 776
Query: 300 PSEEMLELEKER-RELIRSQAVKKNP---GIAAKWWNPPQEKTIEEQLDEEHLESHKKYK 355
P+++ E K +E ++S K+P A P+++ ++ + EE K K
Sbjct: 777 PADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVK 836
Query: 356 ERKERRAQQEQL----LLQKQLQQQQQQPPSQLCTAPASSHERASMIDKAKEDIVTEQID 411
E ++A++E+ +++ ++++ P + P ++ ++K KE V + +
Sbjct: 837 E-PPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKE 895
Query: 412 FSAARKQFQLMENSRQA--VAKGQSTPRLFSIKPFYRPLGSVNSDKPLTNPRPPS--VGG 467
+ +K+ E A K + P+ + P D P P+
Sbjct: 896 EAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEP-----DDAKAKEPSKPAEKKEA 950
Query: 468 PPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKEGPYSEPSKR 513
PE K +K +T + A T S+ P +E +++
Sbjct: 951 APEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEK 996
Score = 38.5 bits (88), Expect = 0.030
Identities = 51/262 (19%), Positives = 106/262 (40%), Gaps = 23/262 (8%)
Query: 673 EQVDKAVSKTSRDGAEQQGPEATVEEAEAAAFGSEKPQSMFE-----PPQVSSPVQEKRD 727
++ V + ++ AE + PE ++ A EK +S + PP+ SP +E+
Sbjct: 514 KEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAK 573
Query: 728 VLPKIL-------PAEDRALRERGPPQPLPAVQPSGPINMEETRPEGSYFSKYSEAAELR 780
++ PA++ A + P + + P+ E P + K E +
Sbjct: 574 SPAEVKSPEKAKSPAKEEA---KSPAEAKSPEKAKSPVKEEAKSPAEA---KSPVKEEAK 627
Query: 781 STASLLATQESDVMVGPFKLRSRK-QRTLSMIEEEIRAAQEREEELKRQRQVLQSTQSPR 839
S A + + +++ P K ++ ++ S +EE ++ ++ + +K + + + +SP
Sbjct: 628 SPAEVKSPEKAK---SPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPV 684
Query: 840 TKNAPSLP-SRTCYKTAPGKIEKVKPPPSPTTEGPSLQPDLAPEEAAGTQRPKNLMQTLM 898
A S +++ K EK K P + P EEA ++ K+ ++
Sbjct: 685 KAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEA 744
Query: 899 EDYETHKSKRRERMDDSSVLEA 920
+ E KS + + D EA
Sbjct: 745 KSPEKAKSPEKAKTLDVKSPEA 766
Score = 38.1 bits (87), Expect = 0.039
Identities = 96/489 (19%), Positives = 169/489 (34%), Gaps = 69/489 (14%)
Query: 468 PPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKEGPYSEPSKRGPLSKLWAEDGEFT 527
PP + AS K KSP E S A ++ S KE S + P E
Sbjct: 504 PPAEEAASPEKEAKSPVKEEAKSPAEAK----SPEKEEAKSPAEVKSPEKAKSPAKEEAK 559
Query: 528 SARAVLTVVKDDDHGILDQFSRSVNVSLTQEELDSGLDELSVRSQDTTVLETLSNDFSMD 587
S + K++ + S S +EE S + S + V E
Sbjct: 560 SPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKE--------- 610
Query: 588 NISDSGASNETTNALQENSLADFSLPQTPQTDNPSEGRGEGVSKSFSDHGFYSPSSTLGD 647
++ + E + ++E + + + + +P++ + K+ S + S
Sbjct: 611 ---EAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAK 667
Query: 648 SPLVDDPLEYQAGLLVQNAIQQAIAEQVDKAVSKTSRDGAEQQGPEATVEEAEAAAFGSE 707
SP+ +A A+ +KA S AE + PE + A E
Sbjct: 668 SPV------------------KAEAKSPEKAKSPVK---AEAKSPEKAKSPVKEEAKSPE 706
Query: 708 KPQSMFE-----PPQVSSPVQEKRDVLPKILPAEDRALRERGPPQPLPAVQPSGPINMEE 762
K +S + P + SPV+E+ P + ++ + P A P ++
Sbjct: 707 KAKSPVKEEAKSPEKAKSPVKEEAKT-----PEKAKSPVKEEAKSPEKAKSPEKAKTLDV 761
Query: 763 TRPEGSYFSKYSEAAELRSTASLLATQESDVMVGPFKLRSRKQRTLSMIEEEIRAAQE-- 820
PE +K + + + + P K +S + E+EI +E
Sbjct: 762 KSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVK 821
Query: 821 ---REEELKRQRQVLQSTQSPRTKNAPSLPSRTCYK-----TAPGK---IEKVKPPPSPT 869
+EEE ++ +V + + + AP+ P K AP K KV+ P
Sbjct: 822 SPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPA 881
Query: 870 TEGPSLQPDLAPEEAAGTQR----PKNLMQTLMEDYETHKSKRRERM-----DDSSVLEA 920
E P A +E A ++ P+ +E E K K + + DD+ E
Sbjct: 882 VEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEP 941
Query: 921 TRVNRRKSA 929
++ +K A
Sbjct: 942 SKPAEKKEA 950
>gi|112421108 capicua homolog [Homo sapiens]
Length = 1608
Score = 45.1 bits (105), Expect = 3e-04
Identities = 104/510 (20%), Positives = 182/510 (35%), Gaps = 73/510 (14%)
Query: 164 GTSSPEPGAVVLVGGLSPPVHEATQPEPTERTASRQAPPHI---ELSNSSPDPMAEAERT 220
GT S +P G P P P S + PP E S +P ++E
Sbjct: 88 GTGSADPERPP--GATCPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETE 145
Query: 221 NGHSPSQPRDALGDSLQVPVSPSSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDKKPS 280
+ H + + +Q+P+ P + +L+ L KE + + + + P+
Sbjct: 146 SDHDDAF-LSIMSPEIQLPLPPGKRRTQ---------SLSALPKER--DSSSEKDGRSPN 193
Query: 281 KLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAK----WWNP--P 334
K +E+ IR RP + K R L+ + ++ +K WW P
Sbjct: 194 K--------REKDHIR--RPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGP 243
Query: 335 QEKT----IEEQLDEEHLESHKKYK------ERKERRAQQEQLLLQKQLQQQQQQPPSQL 384
+EK + Q+ E H ++H +K ++ A+ L L ++ +++ S+
Sbjct: 244 KEKQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKSSSEAKPTSLGLAGGHKETRERSMSET 303
Query: 385 CTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQAVAKGQSTPRLFSIKPF 444
TA A + ++ A + +++ D A E G + PR FS
Sbjct: 304 GTAAAPGVS-SELLSVAAQTLLSS--DTKAPGSSSCGAERLHTVGGPGSARPRAFSHSGV 360
Query: 445 YRPLGSVNSDKPLTNPRPPSVGGPPEDSGASAAKGQKSPGALETPSAAGSQGNTASQGKE 504
+ L D V GP SG + +PG P G G A+ G+
Sbjct: 361 HS-LDGGEVDSQALQELTQMVSGPASYSGPKPSTQYGAPGPFAAP---GEGGALAATGR- 415
Query: 505 GPYSEPSKRGPLSKLWAEDGEFTSARAVLTVVKDDDHGILDQFSRSVNVSLTQEELDSGL 564
P P++ + +ED R V+ + DD I D + ++ L +E
Sbjct: 416 -PPLLPTRASRSQRAASEDMTSDEERMVICEEEGDDDVIADDGFGTTDIDLKCKE----- 469
Query: 565 DELSVRSQDTTVLETLSNDFS-MDNISDSGASNETTNALQENSLADFSLPQTPQTDNPSE 623
V ++ S D S D + G + + + +S P P+ P +
Sbjct: 470 ----------RVTDSESGDSSGEDPEGNKGFGRKVFSPVIRSSFTHCRPPLDPEPPGPPD 519
Query: 624 -----GRGEGVSKSFSDHGFYSPSSTLGDS 648
G+G G + S S S S++ S
Sbjct: 520 PPVAFGKGYGSAPSSSASSPASSSASAATS 549
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 44.7 bits (104), Expect = 4e-04
Identities = 36/155 (23%), Positives = 71/155 (45%), Gaps = 30/155 (19%)
Query: 275 EDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAVKKNPGIAAKWWNPP 334
E +K L ++E E+E+ + R EE+ E E+ER+E
Sbjct: 2236 ELEKQESLSSEEEEEREE---EEEREEEEVREEEEERKE--------------------- 2271
Query: 335 QEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQQPPSQLCTAPASSHER 394
+E+ E+Q+++E E KK KE+K+ Q+++ + +++ + ++ L S E
Sbjct: 2272 EEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESL------SDEE 2325
Query: 395 ASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQAV 429
+ E+ V + + KQF+L E R+++
Sbjct: 2326 EEEESCSLEEEVDREKEILKKEKQFKLQEQRRKSL 2360
Score = 33.5 bits (75), Expect = 0.97
Identities = 28/131 (21%), Positives = 63/131 (48%), Gaps = 11/131 (8%)
Query: 252 SRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKER 311
S + E L L+K+ E ++ + E++ E+E+ + E+ +E E+E
Sbjct: 2227 SEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEE 2286
Query: 312 RELIRSQAVKKNPGIAAKWWNPPQEKTIEEQ---LDEEHLESHKKYKERKERRAQQEQLL 368
++ + + KK + K E+ EE+ + EE ES +E +E + +E++
Sbjct: 2287 KK--KKKKEKKKEEVQEK------EEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVD 2338
Query: 369 LQKQLQQQQQQ 379
+K++ ++++Q
Sbjct: 2339 REKEILKKEKQ 2349
Score = 32.3 bits (72), Expect = 2.2
Identities = 36/148 (24%), Positives = 68/148 (45%), Gaps = 32/148 (21%)
Query: 264 KEAKFELRAFH-EDKKPSKLFEDD-------EHEKEQYCIRKVRPSEEMLELEKERRELI 315
K+A E + H E +K K ++++ E EK K+ P EEML+ +K+ +
Sbjct: 1461 KKAWDEWKQVHGETRKSWKAWKEEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEE 1520
Query: 316 RSQAVKKNPGIAAK--WWNPPQEKTIEEQLDEE-------------HLES-------HKK 353
Q + +K + +E T+EE++ E H++ H+K
Sbjct: 1521 WKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRK 1580
Query: 354 YKERKERRAQQEQLLLQKQ--LQQQQQQ 379
+++RAQ+E+ L Q++ L Q+++Q
Sbjct: 1581 RARAEKKRAQEERKLAQEEEKLAQEERQ 1608
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 44.7 bits (104), Expect = 4e-04
Identities = 41/168 (24%), Positives = 81/168 (48%), Gaps = 9/168 (5%)
Query: 264 KEAKFELRAFHEDKKPS---KLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAV 320
++AK E A + KK + K+ E + K++ R++R ++ E E+ +EL++
Sbjct: 611 EKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEE-ERRHQELLQ---- 665
Query: 321 KKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKER-RAQQEQLLLQKQLQQQQQQ 379
KK + + K + EQ ++E E ++ +ER+E+ R +QE+ ++QL +Q+++
Sbjct: 666 KKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERR 725
Query: 380 PPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQ 427
+ A ER + KE + E + +Q +L E Q
Sbjct: 726 REQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQ 773
Score = 35.8 bits (81), Expect = 0.19
Identities = 31/129 (24%), Positives = 62/129 (48%), Gaps = 14/129 (10%)
Query: 263 KKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRE----LIRSQ 318
K+E + LR E K+ ++ E + E+E R+ + E E+ERRE L +
Sbjct: 668 KEEEQERLRKAAEAKRLAEQREQERREQE----RREQERREQERREQERREQERQLAEQE 723
Query: 319 AVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQ 378
++ + A+ +EK + Q ++ E +K K+ +++Q L ++QLQ++Q+
Sbjct: 724 RRREQERLQAERELQEREKALRLQKEQLQRELEEKKKK------EEQQRLAERQLQEEQE 777
Query: 379 QPPSQLCTA 387
+ + A
Sbjct: 778 KKAKEAAGA 786
Score = 33.9 bits (76), Expect = 0.74
Identities = 47/211 (22%), Positives = 76/211 (36%), Gaps = 34/211 (16%)
Query: 28 REAAAARRWTGAEPQDCAPGSGRPEKPPQLSEDDIWLKSEGDNYSATLLEPAASSLSPDH 87
R AAAA T A AP S PE P L+ K DN++ L P +
Sbjct: 126 RAAAAAAAATMAL---AAPSSPTPESPTMLT------KKPEDNHTQCQLVPVVEIGISER 176
Query: 88 KNMEIEVSVAECKSVPGITSTPHPMDHPSAFYSPPHNGLLTDHHESLDNDVAREIRYLDE 147
+N E V+ + S + T P P++ +P G+ T ES + R L+
Sbjct: 177 QNAEQHVT--QLMSTEPLPRTLSPT--PASATAPTSQGIPTSDEESTPKK--SKARILES 230
Query: 148 VLEANCCDSAVDGTYNGTSSPEPGAVVLVGGLSP-------------------PVHEATQ 188
+ ++ + D G + + + + +SP P+
Sbjct: 231 ITVSSLMATPQDPKGQGVGTGRSASKLRIAQVSPGPRDSPAFPDSPWRERVLAPILPDNF 290
Query: 189 PEPTERTASRQAPPHIELSNSSPDPMAEAER 219
PT Q+ H ++ SSP P A++
Sbjct: 291 STPTGSRTDSQSVRHSPIAPSSPSPQVLAQK 321
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 44.7 bits (104), Expect = 4e-04
Identities = 41/168 (24%), Positives = 81/168 (48%), Gaps = 9/168 (5%)
Query: 264 KEAKFELRAFHEDKKPS---KLFEDDEHEKEQYCIRKVRPSEEMLELEKERRELIRSQAV 320
++AK E A + KK + K+ E + K++ R++R ++ E E+ +EL++
Sbjct: 607 EKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEE-ERRHQELLQ---- 661
Query: 321 KKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKER-RAQQEQLLLQKQLQQQQQQ 379
KK + + K + EQ ++E E ++ +ER+E+ R +QE+ ++QL +Q+++
Sbjct: 662 KKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERR 721
Query: 380 PPSQLCTAPASSHERASMIDKAKEDIVTEQIDFSAARKQFQLMENSRQ 427
+ A ER + KE + E + +Q +L E Q
Sbjct: 722 REQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQ 769
Score = 35.8 bits (81), Expect = 0.19
Identities = 31/129 (24%), Positives = 62/129 (48%), Gaps = 14/129 (10%)
Query: 263 KKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPSEEMLELEKERRE----LIRSQ 318
K+E + LR E K+ ++ E + E+E R+ + E E+ERRE L +
Sbjct: 664 KEEEQERLRKAAEAKRLAEQREQERREQE----RREQERREQERREQERREQERQLAEQE 719
Query: 319 AVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKERRAQQEQLLLQKQLQQQQQ 378
++ + A+ +EK + Q ++ E +K K+ +++Q L ++QLQ++Q+
Sbjct: 720 RRREQERLQAERELQEREKALRLQKEQLQRELEEKKKK------EEQQRLAERQLQEEQE 773
Query: 379 QPPSQLCTA 387
+ + A
Sbjct: 774 KKAKEAAGA 782
Score = 33.9 bits (76), Expect = 0.74
Identities = 47/211 (22%), Positives = 76/211 (36%), Gaps = 34/211 (16%)
Query: 28 REAAAARRWTGAEPQDCAPGSGRPEKPPQLSEDDIWLKSEGDNYSATLLEPAASSLSPDH 87
R AAAA T A AP S PE P L+ K DN++ L P +
Sbjct: 126 RAAAAAAAATMAL---AAPSSPTPESPTMLT------KKPEDNHTQCQLVPVVEIGISER 176
Query: 88 KNMEIEVSVAECKSVPGITSTPHPMDHPSAFYSPPHNGLLTDHHESLDNDVAREIRYLDE 147
+N E V+ + S + T P P++ +P G+ T ES + R L+
Sbjct: 177 QNAEQHVT--QLMSTEPLPRTLSPT--PASATAPTSQGIPTSDEESTPKK--SKARILES 230
Query: 148 VLEANCCDSAVDGTYNGTSSPEPGAVVLVGGLSP-------------------PVHEATQ 188
+ ++ + D G + + + + +SP P+
Sbjct: 231 ITVSSLMATPQDPKGQGVGTGRSASKLRIAQVSPGPRDSPAFPDSPWRERVLAPILPDNF 290
Query: 189 PEPTERTASRQAPPHIELSNSSPDPMAEAER 219
PT Q+ H ++ SSP P A++
Sbjct: 291 STPTGSRTDSQSVRHSPIAPSSPSPQVLAQK 321
>gi|41406089 SRY-box 13 [Homo sapiens]
Length = 622
Score = 44.7 bits (104), Expect = 4e-04
Identities = 71/318 (22%), Positives = 119/318 (37%), Gaps = 38/318 (11%)
Query: 182 PVHEATQPEPTERTASRQAPPHIELSNSSPDPMAEAERTNGHSPSQPRDALGDSLQVPVS 241
P HEA Q T P ++ P A+ S P G+ P
Sbjct: 32 PCHEAPQGSATAAEPQPGDPARASQDSADPQAPAQGNFRGSWDCSSPE---GNGSPEPKR 88
Query: 242 PSSTTSSRCSSRDGEFTLTTLKKEAKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVRPS 301
P + ++ S +F LK+ + D K L + K+ V+ +
Sbjct: 89 PGVSEAASGSQEKLDFN-RNLKEVVPAIEKLLSSDWKERFLGRNSMEAKD------VKGT 141
Query: 302 EEML-ELEKERRELIRSQAVKKNPGIAAKWWNPPQEKTIEEQLDEEHLESHKKYKERKER 360
+E L E E + +I + ++ + A ++K + L E+ + + ++++E+
Sbjct: 142 QESLAEKELQLLVMIHQLSTLRDQLLTAH----SEQKNMAAMLFEKQQQQMELARQQQEQ 197
Query: 361 RAQQEQLLLQKQ-----LQQQQQQPPSQLCTAPA--SSHERASMIDKAKEDIVTEQIDFS 413
A+Q+Q L+Q+Q LQQQ QQ PA SH+ + ++ + + I
Sbjct: 198 IAKQQQQLIQQQHKINLLQQQIQQVNMPYVMIPAFPPSHQPLPVTPDSQLALPIQPIPCK 257
Query: 414 AARKQFQLMENSRQAVAKGQ------------STPRLFSIKPFYRPLGSVNSDKPLTN-- 459
QL+ + V K S P + KP L + +S L
Sbjct: 258 PVEYPLQLLHSPPAPVVKRPGAMATHHPLQEPSQPLNLTAKPKAPELPNTSSSPSLKMSS 317
Query: 460 --PRPPSVGGPPEDSGAS 475
PRPPS GGP D +S
Sbjct: 318 CVPRPPSHGGPTRDLQSS 335
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.306 0.125 0.353
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,587,649
Number of Sequences: 37866
Number of extensions: 2578798
Number of successful extensions: 31309
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 231
Number of HSP's successfully gapped in prelim test: 855
Number of HSP's that attempted gapping in prelim test: 18818
Number of HSP's gapped (non-prelim): 10564
length of query: 948
length of database: 18,247,518
effective HSP length: 112
effective length of query: 836
effective length of database: 14,006,526
effective search space: 11709455736
effective search space used: 11709455736
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.