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Search of human proteins with 51873049
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|51873049 hypothetical protein LOC8603 [Homo sapiens]
(1224 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|51873049 hypothetical protein LOC8603 [Homo sapiens] 2498 0.0
gi|154426272 hypothetical protein LOC54540 [Homo sapiens] 278 3e-74
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 77 8e-14
gi|148746195 trichohyalin [Homo sapiens] 62 4e-09
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 57 1e-07
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 57 1e-07
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 57 1e-07
gi|12751473 DNA cytosine methyltransferase 3 alpha isoform a [Ho... 56 2e-07
gi|28559069 DNA cytosine methyltransferase 3 alpha isoform a [Ho... 56 2e-07
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 56 2e-07
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 56 2e-07
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 56 2e-07
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 56 2e-07
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 56 2e-07
gi|148806928 hypothetical protein LOC57482 [Homo sapiens] 55 3e-07
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 55 3e-07
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 55 3e-07
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 55 4e-07
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 54 7e-07
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 54 9e-07
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom... 54 9e-07
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom... 54 9e-07
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap... 54 9e-07
gi|104526627 triadin [Homo sapiens] 54 9e-07
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 54 9e-07
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 54 1e-06
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 53 2e-06
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 53 2e-06
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 53 2e-06
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 52 3e-06
>gi|51873049 hypothetical protein LOC8603 [Homo sapiens]
Length = 1224
Score = 2498 bits (6473), Expect = 0.0
Identities = 1224/1224 (100%), Positives = 1224/1224 (100%)
Query: 1 MKVRLLRQLSAAAKVKAPSGLQGPPQAHQFISLLLEEYGALCQAARSISTFLGTLENEHL 60
MKVRLLRQLSAAAKVKAPSGLQGPPQAHQFISLLLEEYGALCQAARSISTFLGTLENEHL
Sbjct: 1 MKVRLLRQLSAAAKVKAPSGLQGPPQAHQFISLLLEEYGALCQAARSISTFLGTLENEHL 60
Query: 61 KKFQVTWELHNKHLFENLVFSEPLLQSNLPALVSQIRLGTTTHDTCSEDTYSTLLQRYQR 120
KKFQVTWELHNKHLFENLVFSEPLLQSNLPALVSQIRLGTTTHDTCSEDTYSTLLQRYQR
Sbjct: 61 KKFQVTWELHNKHLFENLVFSEPLLQSNLPALVSQIRLGTTTHDTCSEDTYSTLLQRYQR 120
Query: 121 SEEELRRVAEEWLECQKRIDAYVDEQMTMKTKQRMLTEDWELFKQRRFIEEQLTNKKAVT 180
SEEELRRVAEEWLECQKRIDAYVDEQMTMKTKQRMLTEDWELFKQRRFIEEQLTNKKAVT
Sbjct: 121 SEEELRRVAEEWLECQKRIDAYVDEQMTMKTKQRMLTEDWELFKQRRFIEEQLTNKKAVT 180
Query: 181 GENNFTDTMRHMLSSRLSMPDCPNCNYRRRCACDDCSLSHILTCGIMDPPVTDDIHIHQL 240
GENNFTDTMRHMLSSRLSMPDCPNCNYRRRCACDDCSLSHILTCGIMDPPVTDDIHIHQL
Sbjct: 181 GENNFTDTMRHMLSSRLSMPDCPNCNYRRRCACDDCSLSHILTCGIMDPPVTDDIHIHQL 240
Query: 241 PLQVDPAPDYLAERSPPSVSSASSGSGSSSPITIQQHPRLILTDSGSAPTFCSDDEDVAP 300
PLQVDPAPDYLAERSPPSVSSASSGSGSSSPITIQQHPRLILTDSGSAPTFCSDDEDVAP
Sbjct: 241 PLQVDPAPDYLAERSPPSVSSASSGSGSSSPITIQQHPRLILTDSGSAPTFCSDDEDVAP 300
Query: 301 LSAKFADIYPLSNYDDTEVVANMNGIHSELNGGGENMALKDESPQISSTSSSSSEADDEE 360
LSAKFADIYPLSNYDDTEVVANMNGIHSELNGGGENMALKDESPQISSTSSSSSEADDEE
Sbjct: 301 LSAKFADIYPLSNYDDTEVVANMNGIHSELNGGGENMALKDESPQISSTSSSSSEADDEE 360
Query: 361 ADGESSGEPPGAPKEDGVLGSRSPRTEESKADSPPPSYPTQQAEQAPNTCECHVCKQEAS 420
ADGESSGEPPGAPKEDGVLGSRSPRTEESKADSPPPSYPTQQAEQAPNTCECHVCKQEAS
Sbjct: 361 ADGESSGEPPGAPKEDGVLGSRSPRTEESKADSPPPSYPTQQAEQAPNTCECHVCKQEAS 420
Query: 421 GLTPSAMTAGALPPGHQFLSPEKPTHPALHLYPHIHGHVPLHTVPHLPRPLIHPTLYATP 480
GLTPSAMTAGALPPGHQFLSPEKPTHPALHLYPHIHGHVPLHTVPHLPRPLIHPTLYATP
Sbjct: 421 GLTPSAMTAGALPPGHQFLSPEKPTHPALHLYPHIHGHVPLHTVPHLPRPLIHPTLYATP 480
Query: 481 PFTHSKALPPAPVQNHTNKHQVFNASLQDHIYPSCFGNTPEWNSSKFISLWGSEVMNDKN 540
PFTHSKALPPAPVQNHTNKHQVFNASLQDHIYPSCFGNTPEWNSSKFISLWGSEVMNDKN
Sbjct: 481 PFTHSKALPPAPVQNHTNKHQVFNASLQDHIYPSCFGNTPEWNSSKFISLWGSEVMNDKN 540
Query: 541 WNPGTFLPDTISGSEILGPTLSETRPEALPPPSSNETPAVSDSKEKKNAAKKKCLYNFQD 600
WNPGTFLPDTISGSEILGPTLSETRPEALPPPSSNETPAVSDSKEKKNAAKKKCLYNFQD
Sbjct: 541 WNPGTFLPDTISGSEILGPTLSETRPEALPPPSSNETPAVSDSKEKKNAAKKKCLYNFQD 600
Query: 601 AFMEANKVVMATSSATSSVSCTATTVQSSNSQFRVSSKRPPSVGDVFHGISKEDHRHSAP 660
AFMEANKVVMATSSATSSVSCTATTVQSSNSQFRVSSKRPPSVGDVFHGISKEDHRHSAP
Sbjct: 601 AFMEANKVVMATSSATSSVSCTATTVQSSNSQFRVSSKRPPSVGDVFHGISKEDHRHSAP 660
Query: 661 AAPRNSPTGLAPLPALSPAALSPAALSPASTPHLANLAAPSFPKTATTTPGFVDTRKSFC 720
AAPRNSPTGLAPLPALSPAALSPAALSPASTPHLANLAAPSFPKTATTTPGFVDTRKSFC
Sbjct: 661 AAPRNSPTGLAPLPALSPAALSPAALSPASTPHLANLAAPSFPKTATTTPGFVDTRKSFC 720
Query: 721 PAPLPPATDGSISAPPSVCSDPDCEGHRCENGVYDPQQDDGDESADEDSCSEHSSSTSTS 780
PAPLPPATDGSISAPPSVCSDPDCEGHRCENGVYDPQQDDGDESADEDSCSEHSSSTSTS
Sbjct: 721 PAPLPPATDGSISAPPSVCSDPDCEGHRCENGVYDPQQDDGDESADEDSCSEHSSSTSTS 780
Query: 781 TNQKEGKYCDCCYCEFFGHGGPPAAPTSRNYAEMREKLRLRLTKRKEEQPKKMDQISERE 840
TNQKEGKYCDCCYCEFFGHGGPPAAPTSRNYAEMREKLRLRLTKRKEEQPKKMDQISERE
Sbjct: 781 TNQKEGKYCDCCYCEFFGHGGPPAAPTSRNYAEMREKLRLRLTKRKEEQPKKMDQISERE 840
Query: 841 SVVDHRRVEDLLQFINSSETKPVSSTRAAKRARHKQRKLEEKARLEAEARAREHLHLQEE 900
SVVDHRRVEDLLQFINSSETKPVSSTRAAKRARHKQRKLEEKARLEAEARAREHLHLQEE
Sbjct: 841 SVVDHRRVEDLLQFINSSETKPVSSTRAAKRARHKQRKLEEKARLEAEARAREHLHLQEE 900
Query: 901 QRRREEEEDEEEEEDRFKEEFQRLQELQKLRAVKKKKKERPSKDCPKLDMLTRNFQAATE 960
QRRREEEEDEEEEEDRFKEEFQRLQELQKLRAVKKKKKERPSKDCPKLDMLTRNFQAATE
Sbjct: 901 QRRREEEEDEEEEEDRFKEEFQRLQELQKLRAVKKKKKERPSKDCPKLDMLTRNFQAATE 960
Query: 961 SVPNSGNIHNGSLEQTEEPETSSHSPSRHMNHSEPRPGLGADGDAADPVDTRDSKFLLPK 1020
SVPNSGNIHNGSLEQTEEPETSSHSPSRHMNHSEPRPGLGADGDAADPVDTRDSKFLLPK
Sbjct: 961 SVPNSGNIHNGSLEQTEEPETSSHSPSRHMNHSEPRPGLGADGDAADPVDTRDSKFLLPK 1020
Query: 1021 EVNGKQHEPLSFFFDIMQHHKEGNGKQKLRQTSKASSEPARRPTEPPKATEGQSKPRAQT 1080
EVNGKQHEPLSFFFDIMQHHKEGNGKQKLRQTSKASSEPARRPTEPPKATEGQSKPRAQT
Sbjct: 1021 EVNGKQHEPLSFFFDIMQHHKEGNGKQKLRQTSKASSEPARRPTEPPKATEGQSKPRAQT 1080
Query: 1081 ESKAKVVDLMSITEQKREERKVNSNNNNKKQLNHIKDEKSNPTPMEPTSPGEHQQNSKLV 1140
ESKAKVVDLMSITEQKREERKVNSNNNNKKQLNHIKDEKSNPTPMEPTSPGEHQQNSKLV
Sbjct: 1081 ESKAKVVDLMSITEQKREERKVNSNNNNKKQLNHIKDEKSNPTPMEPTSPGEHQQNSKLV 1140
Query: 1141 LAESPQPKGKNKKNKKKKGDRVNNSIDDVFLPKDIDLDSVDMDETEREVEYFKRFCLDSA 1200
LAESPQPKGKNKKNKKKKGDRVNNSIDDVFLPKDIDLDSVDMDETEREVEYFKRFCLDSA
Sbjct: 1141 LAESPQPKGKNKKNKKKKGDRVNNSIDDVFLPKDIDLDSVDMDETEREVEYFKRFCLDSA 1200
Query: 1201 RQTRQRLSINWSNFSLKKATFAAH 1224
RQTRQRLSINWSNFSLKKATFAAH
Sbjct: 1201 RQTRQRLSINWSNFSLKKATFAAH 1224
>gi|154426272 hypothetical protein LOC54540 [Homo sapiens]
Length = 789
Score = 278 bits (710), Expect = 3e-74
Identities = 245/744 (32%), Positives = 337/744 (45%), Gaps = 123/744 (16%)
Query: 581 SDSKEKKNAAKKKCLYNFQD----AFMEANKVVMATSSATSSVSCTATTVQSSNSQFRVS 636
S S +++ C N D +F+ A+K+ +S SS + +++ S
Sbjct: 60 SSSSSSSSSSSSSCPGNSGDWDPSSFLSAHKLSGLWNSPHSSGAMPGSSLGS-------- 111
Query: 637 SKRPPSVGDVFHGISKEDHRHSAPAAPRNSPTGLAPLPALSPAALSPAALSPASTPHLA- 695
PP++ +S E H+HS AP NSPTG P PA S P++ PHL
Sbjct: 112 ---PPTIPGEAFPVS-EHHQHSDLTAPPNSPTGHHPQPA-SLIPSHPSSFGSPPHPHLLP 166
Query: 696 NLAAPSFPK----------TATTTPGFVDTRK---------------SFCPAPLPPATDG 730
A FP TA TPG + S C P G
Sbjct: 167 TTPAAPFPAQASECPVAAATAPHTPGPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGG 226
Query: 731 SISAP----------PSVCSDPDCEGHRCENGVYD---PQQDDGDESA--DEDSCSEHSS 775
S P PS DP C+GH+ + PQ + DE +EDS SE SS
Sbjct: 227 HCSGPLLPPPSSQPLPSTHRDPGCKGHKFAHSGLACQLPQPCEADEGLGEEEDSSSERSS 286
Query: 776 STSTSTNQKEGKYCDCCYCEFFGHGGPPAAPTSRNYAEMREKLRLRLTKRKEEQPKKMDQ 835
TS+ST+Q++GK+CDCCYCEFFGH PPAAPTSRNY E+REKLR RLT+RKEE P K
Sbjct: 287 CTSSSTHQRDGKFCDCCYCEFFGHNAPPAAPTSRNYTEIREKLRSRLTRRKEELPMKGGT 346
Query: 836 IS--ERESVVDHRRVEDLLQFINSSETKPVSSTRAAKRARHKQRKLE-EKARLEAEARAR 892
+ E VDHR V++LL+FINS+E K +S RAAKRARHK +K E EKA+L AEA +
Sbjct: 347 LGGIPGEPAVDHRDVDELLEFINSTEPKVPNSARAAKRARHKLKKKEKEKAQLAAEALKQ 406
Query: 893 EHLHLQEEQRRREEE---EDEEEEEDRFKEEF-QRLQELQKLRAVKKKKKERPSKDCPKL 948
+ + R E E + E DR RLQE++ K R S +L
Sbjct: 407 ANRVSGSREPRPARERLLEWPDRELDRVNSFLSSRLQEIKN----TVKDSIRASFSVCEL 462
Query: 949 DMLTRNF--QAATESVPNSGNIHNGSLEQTEEPETSSH-------SPSRHMNHSE----- 994
M + F + A E P S N S ++P+ + SP H +
Sbjct: 463 SMDSNGFSKEGAAEPEPQSLPPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQAPGEPAP 522
Query: 995 -----------------PRPGLGADGDAADPVDT----------RDSKFLLPKEVNGKQH 1027
P PG+ + ++T + K P
Sbjct: 523 PWAEMRGPHPPWTEVRGPPPGIVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSSK 582
Query: 1028 EPLSFFFDIMQHHKEGNGKQK-LRQTSKASSEPARRPTEPPKATEGQSKPR--AQTESKA 1084
E S ++ + G QK RQ S+A A PP + E S A +
Sbjct: 583 EVPSCKQELPEPVSSGGKPQKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPKQPG 642
Query: 1085 KVVDLMSITEQKREERKVNSNNNNKKQLNHIKDEKSNPT-----PMEPTSPGEHQQNSKL 1139
+V++L + + K EK + P E + + Q++ +
Sbjct: 643 RVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWPGEAKARPQEQESVQP 702
Query: 1140 VLAESPQ--PKGKNK-KNKKKKGDRVNNSIDDVFLPKDIDLDSVDMDETEREVEYFKRFC 1196
PQ P+GK + + + K ++ +S+DDVFLPK D+D V+MDET+REVEYFKRFC
Sbjct: 703 PGPARPQSLPQGKGRSRRSRNKQEKPASSLDDVFLPK--DMDGVEMDETDREVEYFKRFC 760
Query: 1197 LDSARQTRQRLSINWSNFSLKKAT 1220
LDSA+QTRQ++++NW+NFSLKK T
Sbjct: 761 LDSAKQTRQKVAVNWTNFSLKKTT 784
Score = 36.2 bits (82), Expect = 0.20
Identities = 48/169 (28%), Positives = 63/169 (37%), Gaps = 33/169 (19%)
Query: 341 DESPQISSTSSSSSEADDEEADGESSGEPP----GAPKEDGVLGS--RSPRTEESKADSP 394
D+S SS+SSSSS + G S P A K G+ S S S SP
Sbjct: 53 DDSHSSSSSSSSSSSSSSSSCPGNSGDWDPSSFLSAHKLSGLWNSPHSSGAMPGSSLGSP 112
Query: 395 P----PSYPTQQAEQ------APNTCECHVCKQEASGLTPSAMTAGALPPGHQFLSPEKP 444
P ++P + Q PN+ H + + L PS ++ PP H L P P
Sbjct: 113 PTIPGEAFPVSEHHQHSDLTAPPNSPTGH--HPQPASLIPSHPSSFGSPP-HPHLLPTTP 169
Query: 445 THPALHLYPHIHGHVPL--HTVPHLPRP--------LIHPTLYATPPFT 483
P +P P+ T PH P P P L PPF+
Sbjct: 170 AAP----FPAQASECPVAAATAPHTPGPCQSSHLPSTSMPLLKMPPPFS 214
Score = 32.3 bits (72), Expect = 2.8
Identities = 32/118 (27%), Positives = 47/118 (39%), Gaps = 14/118 (11%)
Query: 383 SPRTEESKADSPPPSYPTQQAEQAPNTCECHVCKQEASGLTPSAMTAGALPPGHQFLSPE 442
S + S + S S P + P++ + + SGL S ++GA+P G SP
Sbjct: 58 SSSSSSSSSSSSSSSCPGNSGDWDPSS---FLSAHKLSGLWNSPHSSGAMP-GSSLGSPP 113
Query: 443 KPTHPALHLYPHIHGHVPLHTVP-----HLPRPLI----HPTLYATPPFTHSKALPPA 491
A + H H H L P H P+P HP+ + +PP H PA
Sbjct: 114 TIPGEAFPVSEH-HQHSDLTAPPNSPTGHHPQPASLIPSHPSSFGSPPHPHLLPTTPA 170
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 77.4 bits (189), Expect = 8e-14
Identities = 84/362 (23%), Positives = 150/362 (41%), Gaps = 37/362 (10%)
Query: 812 AEMREKLRLRLTKRKEEQPKKMDQISERESVVDHRRVEDLLQFINSSETKPVSSTRA--A 869
A R++ R R +R+ E+ ++ D+ E+E ++ R + + + R
Sbjct: 676 ARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDR 735
Query: 870 KRARHKQRKLEEKARLEAEARAREHLHLQEEQRRREEEEDEEEEEDRFKEEFQRLQELQK 929
+R R ++R E++ E E R RE +E +R RE E + E D+ +E + ++ K
Sbjct: 736 ERERERERDREKEREREREERERERERERERERERERERERARERDKERERQRDWEDKDK 795
Query: 930 LRAVKKKKKERPSKDCPKLDMLTRNFQAATESVPNSGNIHNGSLE--QTEEPETSSHSPS 987
R +++K+E +D RN P G+ S + + E + SP
Sbjct: 796 GRDDRREKREEIRED--------RN--------PRDGHDERKSKKRYRNEGSPSPRQSPK 839
Query: 988 RHMNHSEPRPGLGADGDAADPVDTRDSKFLLPKEVNGKQHEPLSFFFDIMQHHKEGNGKQ 1047
R HS D DA + D ++ K L +V Q E S + ++G K+
Sbjct: 840 RRREHS-------PDSDAYNSGDDKNEKHRLLSQVVRPQ-ESRSLSPSHLTEDRQGRWKE 891
Query: 1048 KLRQTSKASSEPARRPTEPPKATEGQSKPRAQTE----SKAKVVDLMSITEQKREERKVN 1103
+ R+ + S E + K R QTE S+ + D++ + + E
Sbjct: 892 EDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDR 951
Query: 1104 SNNNNKK----QLNHIKDEKSNPTPMEPTSPGEHQQNSKLVLAESPQPKGK-NKKNKKKK 1158
+++ NKK Q IK +K + +E + ++ ++ + Q K KK KK K
Sbjct: 952 AHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKRKKSK 1011
Query: 1159 GD 1160
GD
Sbjct: 1012 GD 1013
Score = 37.4 bits (85), Expect = 0.088
Identities = 29/123 (23%), Positives = 59/123 (47%), Gaps = 12/123 (9%)
Query: 826 KEEQPKKMDQISERESVVDHRRVEDLLQFINSSETKPVSSTRAAKR-------ARHKQRK 878
++ P++ ++ R+S + R E + + +P S R R R ++R+
Sbjct: 605 RDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERR 664
Query: 879 LEE-KARLEAEARAREHLHLQEEQRRREEEEDEEEEEDRFKEEFQRLQELQKLRAVKKKK 937
++ R + AR R+ +E +R RE E + E E DR +E+ + L+ + ++++
Sbjct: 665 VDRVDDRRDERARERD----RERERDRERERERERERDREREKERELERERARERERERE 720
Query: 938 KER 940
KER
Sbjct: 721 KER 723
Score = 35.0 bits (79), Expect = 0.44
Identities = 65/343 (18%), Positives = 121/343 (35%), Gaps = 43/343 (12%)
Query: 864 SSTRAAKRARHKQRKLEEKARLEAEARAREHLHLQEEQRRREEEEDEEEEEDRFKEEFQR 923
S R RH+ + EK R + E ++ H RR E ED + DR K+ +
Sbjct: 381 SPQRKQSPPRHRS-PMREKGRHDHERTSQSH------DRRHERREDTRGKRDREKDSREE 433
Query: 924 LQELQKLRAVKKKKKERPSKD----CPKLDMLTRNFQAATESVPNSGNIHNGSLEQTEEP 979
+ Q + + + +R +D D R + + +S + + S + E
Sbjct: 434 REYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESR 493
Query: 980 ETSSHSPSRHMNHSEPRPGLGADGDAADPVDTRDSKFLLPKEVN--GKQHEPLSFFFDIM 1037
+ +R + R G DT + P+E G+ H +
Sbjct: 494 DPRDSRSTRDAHDYRDREGR----------DTHRKEDTYPEESRSYGRNHLREESSRTEI 543
Query: 1038 QHHKEGNGKQKLRQTSKASSEPARRPTEPPKATEGQSKPRAQTESKAKVVDLMSITEQKR 1097
++ + ++R S R P P K + G + + S T
Sbjct: 544 RNESRNESRSEIRNDRMGRSR-GRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSY 602
Query: 1098 EERKVNSNNNNKKQLNHIKDEK---------SNPTPMEPTSPGEHQ-QNSKLVLAESPQP 1147
ER +N+ Q E+ + P+SP HQ +N +L
Sbjct: 603 PERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDEL-------- 654
Query: 1148 KGKNKKNKKKKGDRVNNSIDDVFLPKDIDLDSVDMDETEREVE 1190
++++ ++++ DRV++ D+ +D + + E ERE E
Sbjct: 655 -ERDERREERRVDRVDDRRDERARERDRERERDRERERERERE 696
Score = 34.3 bits (77), Expect = 0.75
Identities = 33/120 (27%), Positives = 55/120 (45%), Gaps = 11/120 (9%)
Query: 809 RNYAEMREKLRLRLTKRKEEQPKKMDQISERESV----VDHRRVEDLLQFINSSETKPVS 864
+++ R++ RLR +R+ E+ K+ D ERE + V+ R D + SS+ + V
Sbjct: 1329 KDWPRNRDRDRLRERERERERDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIESVK 1388
Query: 865 STRAAKRARHKQRKLEEKAR----LEAEARAREHLHLQ--EEQRRREEEEDEEEEEDRFK 918
A H +R LE +R L+ E ++ +Q EE + E E E +D K
Sbjct: 1389 RCEAKLEGEH-ERDLESTSRDSLALDKERMDKDLGSVQGFEETNKSERTESLEAGDDESK 1447
Score = 33.5 bits (75), Expect = 1.3
Identities = 62/373 (16%), Positives = 139/373 (37%), Gaps = 65/373 (17%)
Query: 873 RHKQRKLEEKARLEAEARAREHLHLQEEQRR-REEEEDEEEEEDRFKEEFQRLQELQKLR 931
R +R+ + + + + E +RE +++Q R+ +D E + R + + + ++ ++LR
Sbjct: 412 RRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELR 471
Query: 932 AVKKKKKERPSKDCPK--------------------LDMLTRNFQAATESVPNSGNIHNG 971
+ + R +D + D R+ ++ P +
Sbjct: 472 DSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGR 531
Query: 972 SLEQTEEPETSSHSPSRHMNHSEPR--------------PGLGADGDAADPVDTRDSKFL 1017
+ + E T + SR+ + SE R P G+ G +D+ S
Sbjct: 532 NHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSS--- 588
Query: 1018 LPKEVNGKQHE--PLSFFFDIMQHHKEGNGKQKLRQTS--KASSEPARRPTEPPKATEGQ 1073
N H+ + + E + + + R +S + E RR E
Sbjct: 589 -----NSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNR-----ERD 638
Query: 1074 SKPRAQTESKAKVVDLMSITEQKREERKVNSNNNNKKQLNHIKDEKSNPTPMEPTSPGEH 1133
+P + + + +L +++REER+V+ +++ +DE++ E E
Sbjct: 639 QRPSSPIRHQGRNDELE--RDERREERRVD-------RVDDRRDERARERDRERERDRER 689
Query: 1134 QQNSKLVLAESPQPKGKNKKNKKKKGDRVNNSIDDVFLPKDIDLDSVDMDETEREVEYFK 1193
++ + + + + ++ + ++ +R D +D D D E ERE E +
Sbjct: 690 ERERERERDREREKERELERERAREREREREKERDRERDRDRDHDR----ERERERERDR 745
Query: 1194 RFCLDSARQTRQR 1206
+ R+ R+R
Sbjct: 746 EKEREREREERER 758
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 61.6 bits (148), Expect = 4e-09
Identities = 63/310 (20%), Positives = 130/310 (41%), Gaps = 16/310 (5%)
Query: 816 EKLRLRLTKRKEEQPKKMD------QISERESVVDHRRVEDLLQFINSSETKPVSSTRAA 869
E R R + +EEQ +K++ + E E R E L+ E + R
Sbjct: 264 EPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERRE 323
Query: 870 KRARHKQR--KLEEKARLEAEARAREHLHLQEEQRRREEEEDEEEEEDRFKEEFQRLQEL 927
++ R +Q+ + E++ R E E R + L ++E+ RRE++ E+EE+R +++ +R Q+L
Sbjct: 324 QQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQL 383
Query: 928 QKLRAVKKKKKERPSKDCPKLDMLTRNFQAATESVPNSGNIHNGSLEQTEEPETSSHSPS 987
++ + ++++++ R + + L R Q E EQ EE H
Sbjct: 384 RREQQLRREQQLRREQQLRREQQLRREQQLRREQ--QLRREQQLRREQEEERHEQKHEQE 441
Query: 988 RH-----MNHSEPRPGLGADGDAADPVDTRDSKFLLPKEVNGKQHEPLSFFFDIMQHHKE 1042
R E R L + + R + L + ++ L + + +E
Sbjct: 442 RREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQE 501
Query: 1043 GNGKQKLRQTSKASSEPARRPTEPPKATEG-QSKPRAQTESKAKVVDLMSITEQKREERK 1101
+Q R+ + + +R E + + +S+ + + E + + L+ E+KR E++
Sbjct: 502 RREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQE 561
Query: 1102 VNSNNNNKKQ 1111
++Q
Sbjct: 562 RREQRLKREQ 571
Score = 55.5 bits (132), Expect = 3e-07
Identities = 69/316 (21%), Positives = 136/316 (43%), Gaps = 30/316 (9%)
Query: 815 REKLRLRLTKRKEEQPKKMDQISERESVVDHRRVEDLLQFINSSETKPVSSTRAAKRARH 874
+E+ R +L KR+EE K+++Q RE + + E Q + E + + + R
Sbjct: 542 QEERREQLLKREEE--KRLEQ-ERREQRLKREQEERRDQLLKREEERRQQRLKREQEERL 598
Query: 875 KQR-KLEEKARLEAEARAREHLHLQ--EEQRRREEEEDEEEEEDRFKEEFQRLQELQKLR 931
+QR K EE RLE E R + L + EE+RR++ + EE+EE R ++ + QE ++ R
Sbjct: 599 EQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQR 658
Query: 932 AVKKKKKERPSKDCPKLDMLTRNFQAATESVPNSGNIHNGSLEQTEEPETSSHSPSRHMN 991
+++++ER + + R Q E S + + S + +R
Sbjct: 659 LKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSK 718
Query: 992 -HSEPR--PGLGADGDAADPVDTRDSKFLLPKEVNG-----KQHEPLSFFFDIMQHHKEG 1043
+S PR G + + R+S+ +E ++ + F + K
Sbjct: 719 VYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSE 778
Query: 1044 NGKQKLRQTSKASSEPARRPTEPPKATEGQSKPRAQTESKAKVVDLMSITEQKREERKVN 1103
G+Q+L AR P + + +++ R Q E + + E++ +E++
Sbjct: 779 RGRQRL---------SARPPLREQRERQLRAEERQQREQR-------FLPEEEEKEQRRR 822
Query: 1104 SNNNNKKQLNHIKDEK 1119
+K+L +++E+
Sbjct: 823 QRREREKELQFLEEEE 838
Score = 52.4 bits (124), Expect = 3e-06
Identities = 75/409 (18%), Positives = 157/409 (38%), Gaps = 44/409 (10%)
Query: 813 EMREKLRLRLTKRKEEQPKKMDQISERESVVDHRRVEDLLQFINSSETKPVSSTRAAKRA 872
E + + R + K EQ ++ D + E H + Q E +
Sbjct: 435 EQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQE----------EER 484
Query: 873 RHKQRKLEEKARLEAEARAREHLHLQEEQRR-----REEEEDEEEEEDRFKEEFQRLQEL 927
R + KLEE+ R E + R + L ++E+RR R+EEE+ ++ R +++ +R QE
Sbjct: 485 RERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEE 544
Query: 928 QKLRAVKKKKKERPSKDCPKLDMLTRNFQAATESVPNSGNIHNGSLEQTEEPETSSHSPS 987
++ + +K+++++R ++ + + + + + L++ +E
Sbjct: 545 RREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKR 604
Query: 988 RHMNHSEPRPGLGADGDAADPVDTRDSKFLLPKEVNGKQHEPLSFFFDIM--QHHKEGNG 1045
+ E +P + R + L +E ++ + L Q K
Sbjct: 605 EEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEE 664
Query: 1046 KQKLRQTSKASSEPARRPTEPPKATEGQSKPRA---------QTESKA-----KVVDLMS 1091
+++L Q K E RR E + + Q++ R Q ES+A KV
Sbjct: 665 EERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPR 724
Query: 1092 ITE-QKREERKVNSNNNNKKQLNHIKDEKSNPTPMEPT---------SPGEHQQNSKLVL 1141
E Q+R + + + +L ++E+++ E E + + L
Sbjct: 725 KQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRL 784
Query: 1142 AESPQPKGKNKKNKKKKGDRVNNSIDDVFLPKDIDLDSVDMDETEREVE 1190
+ P P + ++ + + +R + FLP++ + + ERE E
Sbjct: 785 SARP-PLREQRERQLRAEERQQR--EQRFLPEEEEKEQRRRQRREREKE 830
Score = 48.9 bits (115), Expect = 3e-05
Identities = 65/348 (18%), Positives = 138/348 (39%), Gaps = 44/348 (12%)
Query: 809 RNYAEMREKLRLRLTKR-KEEQPKKMDQISERESVVDHRRVEDLLQFINSSETKPVSSTR 867
R ++R + +LR ++ + EQ + +Q RE + + E+ + + E + R
Sbjct: 390 RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKR 449
Query: 868 AAKRARHKQRKLEEKARLEAEARAREHLHLQEEQRRR-----EEEEDEEEEEDRFKEEFQ 922
+ R ++ EE R E E R ++ QEE+RR EEEE E++E R ++ +
Sbjct: 450 EQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRR 509
Query: 923 RLQELQKLRAVKKKKKERPSKDCPKLDMLTRNFQAATESVPNSGNIHNGSLEQTEEPETS 982
+E ++ R +++++ER + L R + E + L++ EE
Sbjct: 510 EQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQL----------LKREEEKRLE 559
Query: 983 SHSPSRHMNHSEPRPGLGADGDAADPVDTRDSKFLLPKEVNGKQHEPLSFFFDIMQHHKE 1042
+ + + + RD LL +E +Q ++ +E
Sbjct: 560 QERREQRLKREQE--------------ERRDQ--LLKREEERRQQR--------LKREQE 595
Query: 1043 GNGKQKLRQTSKASSEPARRPTEPPKATEGQSKPRAQ----TESKAKVVDLMSITEQKRE 1098
+Q+L++ E R + K E + + R Q E + + + +Q+R
Sbjct: 596 ERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERR 655
Query: 1099 ERKVNSNNNNKKQLNHIKDEKSNPTPMEPTSPGEHQQNSKLVLAESPQ 1146
E+++ ++ +K E + + E +Q + + + P+
Sbjct: 656 EQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPK 703
Score = 48.1 bits (113), Expect = 5e-05
Identities = 75/409 (18%), Positives = 156/409 (38%), Gaps = 44/409 (10%)
Query: 809 RNYAEMREKLRLRLTKRKEEQPKKMDQISERESVVDHRRVEDLLQF-----INSSETKPV 863
R E R + R+EEQ ++ ++ RE RR E Q+ + E + +
Sbjct: 915 REEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLL 974
Query: 864 SSTRAAKRARHKQRKLEEKARLEAEA--------------------RAREHLHLQEEQRR 903
+R + +++K E+ L+ E R ++ L +EEQ
Sbjct: 975 GEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLL 1034
Query: 904 REEEEDE--EEEEDRFKEEFQRLQELQKLRAVKKKKKERP--SKDCPKLDMLTRNFQAAT 959
REE E +E E +++EE + QE ++L +++ + R + K + L + +
Sbjct: 1035 REEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLL 1094
Query: 960 ESVPNSGNIHNGSLEQTEEPETSSHSPSRHMNHSEPRPGLGADGDAADPVDT-RDSKFLL 1018
P + EE E E R + + + ++ + LL
Sbjct: 1095 REEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLL 1154
Query: 1019 PKEVNGKQHEPLSFFFDIMQHHKEGNGKQKLRQTSKASSEPARRPTEPPKATEGQSKPRA 1078
+E ++ + L Q+ +E +Q+ Q + E R+ E + E + R
Sbjct: 1155 REEPEKRRRQELE-----RQYREEEELQQEEEQLLREEQEKRRQERE-RQYREEEELQRQ 1208
Query: 1079 QTESKAKVVDLMSITEQKREERKVNSNNNNKKQLNHIKDEKSNPTPMEPTSPGEHQQNSK 1138
+ + + + D S + + E K N+ +NK ++E+ + QQ+ +
Sbjct: 1209 KRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQ 1268
Query: 1139 LVLAESPQPKGKNKKNKKKKGDRVNNSIDDVFLPKDIDLDSVDMDETER 1187
+L E + + ++ + ++ DR P++ L+ + E +R
Sbjct: 1269 HLLGEQQERDREQERRRWQQRDR--------HFPEEEQLEREEQKEAKR 1309
Score = 47.8 bits (112), Expect = 7e-05
Identities = 72/393 (18%), Positives = 159/393 (40%), Gaps = 31/393 (7%)
Query: 826 KEEQPKKMDQISERESVVDHRRVEDLLQFINSSETKPVSSTRAAKRARHKQRKLEEKARL 885
+E+Q ++ Q R+ + E+ + ++ KP + K + Q + EE R
Sbjct: 857 QEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQRE 916
Query: 886 EAEARAREHLHLQEEQRRREEEEDEEEEEDRFKEEFQRLQELQKLRAVKKKKKERPSKDC 945
E E R R+ ++E++ REEE+ ++EEE +EE ++ + ++ R +K KK + ++
Sbjct: 917 EREKRRRQ----EQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEE- 971
Query: 946 PKLDMLTRNFQAATESVPNSGNIHNGSLEQTEEPETSSHSPSRHMNHSEPRPGLGADGDA 1005
+L + L+Q EE R E + +
Sbjct: 972 ---QLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQ 1028
Query: 1006 ADPV---DTRDSKFLLPKEVNGKQHEPLSFFFD-IMQHHKEGNGKQKLRQTSKASSEPAR 1061
+ + R+ + L +E ++ E L + ++ +E +Q+L + + E +
Sbjct: 1029 EEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYR-KEEELQ 1087
Query: 1062 RPTEPPKATEGQSKPRAQTESKAKVVDLMSITEQK--REERKVNSNNNNKKQLNHIKDEK 1119
+ E E + + R + E + + + + E++ REER+ ++Q ++E+
Sbjct: 1088 QEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQ---YREEE 1144
Query: 1120 SNPTPMEPTSPGEHQQNSKLVLAESPQPKGKNKKNKKKKGDRVNNSIDDVFLPKDIDLDS 1179
E QQ + +L E P+ + + + ++ + + ++ L ++ +
Sbjct: 1145 ------------EVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRR 1192
Query: 1180 VDMDETEREVEYFKRFCLDSA-RQTRQRLSINW 1211
+ + RE E +R R QR + W
Sbjct: 1193 QERERQYREEEELQRQKRKQRYRDEDQRSDLKW 1225
Score = 47.4 bits (111), Expect = 9e-05
Identities = 66/415 (15%), Positives = 178/415 (42%), Gaps = 32/415 (7%)
Query: 813 EMREKLRLRLTKRKEEQPKKMDQISERESVVDHRRVEDLLQFINSSETKPVSSTRAAKRA 872
+ +++LR R++++ ++ +Q ER + R ++ + + + +R
Sbjct: 295 QQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRRE 354
Query: 873 RHKQRKLEEKARLEAEARAREHLHLQEEQRRREEEEDEEEEEDRFKEEFQRLQELQKLRA 932
+ ++R+ E++ R E E RE L+ EQ+ R E++ E++ R +++ +R Q+L++ +
Sbjct: 355 QEEERR-EQQLRREQEEERREQ-QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 412
Query: 933 VKKKKKERPSKDCPKLDMLTRNFQAATESVPNSGNIHNGSLEQTE----EPETSSHSPSR 988
++++++ R + + R+ Q E + E+ + E ET H R
Sbjct: 413 LRREQQLRREQQLRREQEEERHEQ-KHEQERREQRLKREQEERRDWLKREEETERHEQER 471
Query: 989 H-----MNHSEPRPGLG---ADGDAADPVDTRDSKFLLPKEVNGKQHEPLSFFFDIMQHH 1040
+ E R + + + + R+ + L +E ++ + L + +
Sbjct: 472 RKQQLKRDQEEERRERWLKLEEEERREQQERREQQ--LRREQEERREQRLKRQEEEERLQ 529
Query: 1041 KEGNGKQKLRQTSKASSEPARRPTEPPKATEGQSKPRAQTESKAKVVDLMSITEQKREER 1100
+ +Q+LR+ + E + E + + + + R + E + + L+ E++R++R
Sbjct: 530 QRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQR 589
Query: 1101 KVNSNNN------NKKQLNHIKDEKSNPTPMEPTSPGEHQQNSKLVLAESPQPKGK--NK 1152
++++ ++ E+ ++ P E ++ L E + + + +
Sbjct: 590 LKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRR 649
Query: 1153 KNKKKKGDRVNNSIDDVFLPKDIDLDSVDMDETEREVEYFKRFCLDSARQTRQRL 1207
+ ++++ R+ ++ L + + + +E RE E + + Q R+R+
Sbjct: 650 EQQERREQRLKREEEEERLEQRLKREH---EEERREQELAE----EEQEQARERI 697
Score = 47.0 bits (110), Expect = 1e-04
Identities = 37/138 (26%), Positives = 66/138 (47%), Gaps = 6/138 (4%)
Query: 809 RNYAEMREKLRLRLTKRKEE--QPKKMDQISERESVVDHRRVEDLLQFINSSETKPVSST 866
R ++R + R R + +E+ Q ++ Q+ +ES R E L Q + +P
Sbjct: 1759 REEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRD 1818
Query: 867 RAAKRARHKQRKLEEKARLEAEA----RAREHLHLQEEQRRREEEEDEEEEEDRFKEEFQ 922
+ + + E++ RL E RA E QE+ RR E+E +EEE+ R +E +
Sbjct: 1819 GKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERER 1878
Query: 923 RLQELQKLRAVKKKKKER 940
+L+E R K++++ R
Sbjct: 1879 KLREEHIRRQQKEEQRHR 1896
Score = 46.6 bits (109), Expect = 1e-04
Identities = 75/393 (19%), Positives = 155/393 (39%), Gaps = 40/393 (10%)
Query: 809 RNYAEMREKLRLRLTKRKEEQPKKMDQISERESVVDHRRVEDLLQFINSSETKPVSSTRA 868
R + E ++LR + +RK + ++ + ERE + R + E + +S
Sbjct: 1374 RKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFRE-----EEQQLSRQER 1428
Query: 869 AKRARHKQRKLEEKAR----LEAEARAREHLH---LQEEQRRREEEEDEEEEEDRFKEEF 921
++ R +++++ + R LE E + R+ H +EEQ +E EE + ++R ++
Sbjct: 1429 DRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFL 1488
Query: 922 QRLQELQKLRAVKKKKKERPSKDCPKLDMLTRNFQAATESVPNSGNIHNGSLEQTEEPET 981
+ Q+L++ +K +++ P+ L Q + L + E +
Sbjct: 1489 EEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQ 1548
Query: 982 SSHSPSRHMNHSEPRPGLGADGDAADPVDTRDSKFLLPKEVNGKQHEPLSFFFDIMQHHK 1041
R E + + RD KF L ++ +Q + F D Q +
Sbjct: 1549 RRQDRDRKFREEEQLRQEREEQQLSR--QERDRKFRLEEQKVRRQEQERKFMEDEQQLRR 1606
Query: 1042 EGNGKQKLRQTSKASSEPARRPTEPPKATEGQSKPRAQTESKAKVVDLMSITEQKREERK 1101
+ G+Q+LRQ R + + E Q R + + K L + +R+ER
Sbjct: 1607 Q-EGQQQLRQ---ERDRKFREDEQLLQEREEQQLHRQERDRKF----LEEEPQLRRQER- 1657
Query: 1102 VNSNNNNKKQLNHIKDEKSNPTPMEPTSPGEHQQNSKLVLAESPQPKGKNKKNKKKKGDR 1161
++QL H +D K + GE QQ + + +++K ++++
Sbjct: 1658 -------EQQLRHDRDRKFREEE-QLLQEGEEQQLRR---------QERDRKFREEEQQL 1700
Query: 1162 VNNSIDDVFLPKDIDLDSVDMDETEREVEYFKR 1194
+ FL ++ L +++ RE E ++
Sbjct: 1701 RRQERERKFLQEEQQLRRQELERKFREEEQLRQ 1733
Score = 44.3 bits (103), Expect = 7e-04
Identities = 65/363 (17%), Positives = 142/363 (39%), Gaps = 54/363 (14%)
Query: 815 REKLRLRLTKRKEEQPKK---MDQISERESVVDHRRVEDLLQFINSSETKPVSSTRAAKR 871
RE L LR R+E+Q ++ D++ + E + R+ E +L
Sbjct: 213 RELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVL------------------- 253
Query: 872 ARHKQRKLEEKARLEAEARAREHLHLQEEQRRREEEEDEEEEEDRFKEEFQRLQELQKLR 931
RK EEK + E R RE L +EEQ R+ E ++ E +++ QRL+ Q+LR
Sbjct: 254 -----RKEEEKLQEEEPQRQRE-LQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLR 307
Query: 932 AVKKKKKERPSKDCPKLDMLTRNFQAATESVPNSGNIHNGSLEQTEEPETSSHSPSRHMN 991
+K+++ER + + + R Q EQ E + +
Sbjct: 308 --RKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLR 365
Query: 992 HSEPRPGLGADGDAADPVDTRDSKFLLPKEVNGKQHEPLSFFFDIMQHHKEGNGKQKLRQ 1051
+ + + + R+ + +++ +Q ++ ++ +Q+LR+
Sbjct: 366 REQ-------EEERREQQLRREQQLRREQQLRREQQ---------LRREQQLRREQQLRR 409
Query: 1052 TSKASSEPARRPTEPPKATEGQSKPRAQTESKAKVVDLMSITEQKR------EERKVNSN 1105
+ E R + + + + + + E + + L E++R EE + +
Sbjct: 410 EQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQ 469
Query: 1106 NNNKKQLNHIKDEKSNP--TPMEPTSPGEHQQNSKLVLAESPQPKGKNKKNKKKKGDRVN 1163
K+QL ++E+ +E E Q+ + L + + + + ++++ +R+
Sbjct: 470 ERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQ 529
Query: 1164 NSI 1166
+
Sbjct: 530 QRL 532
Score = 42.4 bits (98), Expect = 0.003
Identities = 32/116 (27%), Positives = 58/116 (50%), Gaps = 10/116 (8%)
Query: 825 RKEEQPKKMDQISERESVVDHRRVEDLLQFINSSETKPVSSTRAAKRARHKQRKLEEKAR 884
++EE+ K+ Q ER+ + + ++ Q + K R +R K +KL++K
Sbjct: 914 QREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQER--ERQYRKDKKLQQKEE 971
Query: 885 L----EAEARAREHLHLQEEQRRREEEEDEEEEEDRFKEEFQRLQELQKLRAVKKK 936
E E R R+ + E++ REEEE ++EEE +EE ++ + + R +KK
Sbjct: 972 QLLGEEPEKRRRQ----EREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKK 1023
Score = 42.4 bits (98), Expect = 0.003
Identities = 32/135 (23%), Positives = 70/135 (51%), Gaps = 5/135 (3%)
Query: 813 EMREKLRLRLTKRKEEQPKKMDQISERESVVDHRRVEDLLQFINSSETKPVSSTRAAKRA 872
++R + R R + +E+Q ++ ++ + R ++L + E + + R
Sbjct: 1683 QLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRR 1742
Query: 873 RHKQRKLEEKARLEAEARAREHLHLQEEQRR-REEEEDEEEEED---RFKEEFQRLQELQ 928
+ + RK+ E+ +L E R + L QE R+ REEE+ +E E+ R +E ++ +E +
Sbjct: 1743 QERYRKILEEEQLRPE-REEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEE 1801
Query: 929 KLRAVKKKKKERPSK 943
+LR +++++ RP +
Sbjct: 1802 QLRQEREEQQLRPQQ 1816
Score = 42.0 bits (97), Expect = 0.004
Identities = 82/431 (19%), Positives = 168/431 (38%), Gaps = 57/431 (13%)
Query: 813 EMREKLRLRLTKRKEEQPKKMDQISERESVVDHRRVEDLLQFINSSETKPVSSTRAAKRA 872
E E+ + KR++ + ++ Q+ E RR E +F + + +R
Sbjct: 1297 EQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQ 1356
Query: 873 RHKQRKLEEKARLEAEAR------------AREHLHLQEEQRRREEEEDEEEEEDR---F 917
++ EE+ R + + R RE L+EEQ+ R +E +++ +DR F
Sbjct: 1357 ERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKF 1416
Query: 918 KEEFQRLQELQKLRAVKK-----KKKERPSKDCPKLDMLT----RNFQAATESVP--NSG 966
+EE Q+L ++ R ++ +++ER K + L R F+ + +
Sbjct: 1417 REEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQ 1476
Query: 967 NIHNGSLEQ---TEEPETSSHSPSRHMNHSEPRPGLGADGDAADPVDTRDSKFLLPKEVN 1023
+H ++ EE + R E R + +P + KFL ++
Sbjct: 1477 QLHRQERDRKFLEEEQQLRRQERDRKFREQELR--------SQEP----ERKFLEEEQQL 1524
Query: 1024 GKQHEPLSFFFDIMQHHKEGNGKQKLRQTSKASSEPARRPTEPPKATEGQSKPRAQTESK 1083
+Q F + Q ++ G+Q+ + + E + E E Q R + + K
Sbjct: 1525 HRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQE----REEQQLSRQERDRK 1580
Query: 1084 AKVVD-LMSITEQKR---EERKVNSNNNNKKQLNHIKDEKSNPTPMEPTSPGE----HQQ 1135
++ + + EQ+R E+ + ++QL +D K E Q+
Sbjct: 1581 FRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQE 1640
Query: 1136 NSKLVLAESPQPKGKNKKNKKKKGDRVNNSIDDVFLPKDIDLDSVDMDETEREVEYFKRF 1195
+ L E PQ + + ++ ++ + DR ++ L ++ + + E +R+ F+
Sbjct: 1641 RDRKFLEEEPQLR-RQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRK---FREE 1696
Query: 1196 CLDSARQTRQR 1206
RQ R+R
Sbjct: 1697 EQQLRRQERER 1707
Score = 41.6 bits (96), Expect = 0.005
Identities = 77/365 (21%), Positives = 138/365 (37%), Gaps = 42/365 (11%)
Query: 815 REKLRLRLTKRKEEQPKKMDQISERESVVDHRRVEDLLQFINSSETKPVSSTRAAKRARH 874
RE+ R R +R P++ +Q+ E RR + E + + R KR R
Sbjct: 1279 REQERRRWQQRDRHFPEE-EQLEREEQKEAKRRDRK-----SQEEKQLLREEREEKRRRQ 1332
Query: 875 K-QRKLEEKARLEAEARAREHLHLQEEQRR-REEEEDEEEEEDRFKEEFQR--------- 923
+ RK E+ +L E R + L QE R+ REEE +E+ +F EE QR
Sbjct: 1333 ETDRKFREEEQLLQE-REEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERK 1391
Query: 924 -LQELQKLRAVKKKKKERPSKDCPKLDMLTRNFQAATESVPNSGNIHNGSLEQTEEPETS 982
L+E Q+LR +++++ R +D R F+ + + + E E
Sbjct: 1392 FLKEEQQLRCQEREQQLRQDRD--------RKFREEEQQLSRQERD-----RKFREEEQQ 1438
Query: 983 SHSPSRHMNHSEPRPGLGADGDAADPVDTRDSKFLLPKEVNGKQH--EPLSFFFDIMQHH 1040
R E L + R+ + LL + + H E F + Q
Sbjct: 1439 VRRQERERKFLEEEQQLRQERHR----KFREEEQLLQEREEQQLHRQERDRKFLEEEQQL 1494
Query: 1041 KEGNGKQKLRQTSKASSEPARRPTEPPKATEGQSKPR--AQTESKAKVVDLMSITEQKRE 1098
+ +K R+ S EP R+ E + Q + R Q E + + + Q R+
Sbjct: 1495 RRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRD 1554
Query: 1099 E--RKVNSNNNNKKQLNHIKDEKSNPTPMEPTSPGEHQQNSKLVLAESPQPKGKNKKNKK 1156
R+ +++ + E+ +E +Q K + E + + ++ +
Sbjct: 1555 RKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLR 1614
Query: 1157 KKGDR 1161
++ DR
Sbjct: 1615 QERDR 1619
Score = 41.2 bits (95), Expect = 0.006
Identities = 35/138 (25%), Positives = 67/138 (48%), Gaps = 25/138 (18%)
Query: 809 RNYAEMREKLRLRLTKRKEEQPKKMDQISERESVVDHRRVEDLLQFINSSETKPVSSTRA 868
R + + ++LR + +RK + +++ Q +E+E + RR E + + + +P +
Sbjct: 1707 RKFLQEEQQLRRQELERKFREEEQLRQETEQEQL---RRQERYRKILEEEQLRPEREEQQ 1763
Query: 869 AKRARHKQRKLEEKARLEAEARAREHLHLQE--------EQRRREEEEDE---------- 910
+R + + RK E+ +L E R + L QE EQ R+E EE +
Sbjct: 1764 LRR-QERDRKFREEEQLRQE-REEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKY 1821
Query: 911 --EEEEDRFKEEFQRLQE 926
EEE+ + +E+ QRL++
Sbjct: 1822 RWEEEQLQLEEQEQRLRQ 1839
Score = 39.7 bits (91), Expect = 0.018
Identities = 65/354 (18%), Positives = 145/354 (40%), Gaps = 50/354 (14%)
Query: 813 EMREKLRLRLTKRKEEQPKKMDQISERESVVDHRRVEDLLQFINSSETKPVSSTRAAKRA 872
++R++ +L + +E Q ++ ++ +E +R E L Q E + + R +R
Sbjct: 898 QLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQ----EEEQLLREEREKRRR 953
Query: 873 RHKQRKLEEKARLEAEARAREHLHLQEEQRRREEEEDE--EEEEDRFKEEFQRLQELQKL 930
+ ++R+ + +L+ + + L + E+RRR+E E + EEEE + +EE Q L+E ++
Sbjct: 954 QERERQYRKDKKLQQ--KEEQLLGEEPEKRRRQEREKKYREEEELQ-QEEEQLLREEREK 1010
Query: 931 RAVKKKKKERPSKDCPKLDMLTRNFQAATESVPNSGNIHNGSLEQTEEPETSSHSPSRHM 990
R ++ +++ KD L+Q EE R +
Sbjct: 1011 RRRQEWERQYRKKD---------------------------ELQQEEEQLLREEREKRRL 1043
Query: 991 NHSEPRPGLGADGDAADPVDTRDSKFLLPKEVNGKQHEPLSFFFDIMQHHKEGNGKQKLR 1050
E + + ++ + LL +E ++ + L Q+ KE +Q+
Sbjct: 1044 QERERQ-------YREEEELQQEEEQLLGEERETRRRQELE-----RQYRKEEELQQEEE 1091
Query: 1051 QTSKASSEPARRPTEPPKATEGQSKPRAQTESKAKVVDLMSITEQKREERKVNSNNNNKK 1110
Q + E RR + E + + + + + + E +R+ R+ ++
Sbjct: 1092 QLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEE 1151
Query: 1111 QLNHIKDEKSNPTPMEP--TSPGEHQQNSKLVLAESPQPKGKNKKNKKKKGDRV 1162
QL + EK +E E QQ + +L E + + + ++ + ++ + +
Sbjct: 1152 QLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEEL 1205
Score = 38.9 bits (89), Expect = 0.030
Identities = 50/248 (20%), Positives = 95/248 (38%), Gaps = 36/248 (14%)
Query: 875 KQRKLEEKARLEAEARA-REHLHLQEEQRRREEEEDEEEEEDRFKEEFQRLQELQKLRAV 933
KQ +LE++ R + R+ QE + RR EEE + + EEF ++L++ +
Sbjct: 157 KQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELL 216
Query: 934 KKKKKERPSKDCPKLDMLTRNFQAATESVPNSGNIHNGSLEQTEEPETSSHSPSRHMNHS 993
+ ++K R K + + R FQ E ++ + EE + P R
Sbjct: 217 ELRRKGREEKQQQRRERQDRVFQEEEEKEWRK----RETVLRKEEEKLQEEEPQRQRELQ 272
Query: 994 EPRPGLGADGDAADPVDTRDSKFLLPKEVNGKQHEPLSFFFDIMQHHKEGNGKQKLRQTS 1053
E L + L +E+ ++ E E +Q+LR+
Sbjct: 273 EEEEQL---------------RKLERQELRRERQE-------------EEQQQQRLRREQ 304
Query: 1054 KASSEPARRPTEPPKATEGQSKPRAQTESKAKVVDLMSITEQKREE--RKVNSNNNNKKQ 1111
+ + E + Q + R Q E + + L E++RE+ R+ ++Q
Sbjct: 305 QLRRKQEEERREQQEERREQQERREQQEER-REQQLRREQEERREQQLRREQEEERREQQ 363
Query: 1112 LNHIKDEK 1119
L ++E+
Sbjct: 364 LRREQEEE 371
Score = 38.9 bits (89), Expect = 0.030
Identities = 69/354 (19%), Positives = 133/354 (37%), Gaps = 40/354 (11%)
Query: 813 EMREKLRLRLTKRKEEQPKKMDQISE------RESVVDHRRVEDLLQFINSSETKPVSST 866
E + LR KR++E+ ++ + E ++ D + DL + V
Sbjct: 1179 EEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDN 1238
Query: 867 RAAKRARHKQ--RKLEEKARLEAEARAR-EHLHLQEEQRRREEEEDEEEEEDR-FKEEFQ 922
+ + R + R+LE+ + +++ +HL ++++R RE+E ++ DR F EE Q
Sbjct: 1239 KVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQ 1298
Query: 923 RLQELQKLRAVKKKKKERPSKDCPKLDMLTRNFQAATESVPNSGNIHNGSLEQTEEPETS 982
+E QK + K+++R S++ +L R + + L++ EE
Sbjct: 1299 LEREEQK----EAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLR 1354
Query: 983 SHSPSRHMNHSEPRPGLGADGDAADPVDTRDSKFLLPKEVNGKQHEPLSFFFDIMQHHKE 1042
R E R + KFL ++ +Q F + Q +
Sbjct: 1355 RQERDRKFREEELRH------------QEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQ 1402
Query: 1043 GNGKQKLRQTSKASSEPARRPTEPPKATEGQSKPRAQTESKAKVVDLMSITEQKREERKV 1102
+Q+LRQ + R+ E + Q + R E + +V ++ ERK
Sbjct: 1403 -EREQQLRQ------DRDRKFREEEQQLSRQERDRKFREEEQQV-------RRQERERKF 1448
Query: 1103 NSNNNNKKQLNHIKDEKSNPTPMEPTSPGEHQQNSKLVLAESPQPKGKNKKNKK 1156
+Q H K + E H+Q E Q + ++++K
Sbjct: 1449 LEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRK 1502
Score = 38.9 bits (89), Expect = 0.030
Identities = 36/132 (27%), Positives = 67/132 (50%), Gaps = 5/132 (3%)
Query: 813 EMREKLRLRLTKRKEEQPKKMDQISE-RESVVDHRRVEDLLQFINSSETKPVSSTRAAKR 871
+ RE+ +L L + +E+Q ++ ++ + RE RR E +F+ + R
Sbjct: 1668 KFREEEQL-LQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFR 1726
Query: 872 ARHKQRKLEEKARLEAEARAREHLHLQEEQRRREEEEDEEEEEDR-FKEEFQRLQEL--Q 928
+ R+ E+ +L + R R+ L ++ + REE++ +E DR F+EE Q QE Q
Sbjct: 1727 EEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQ 1786
Query: 929 KLRAVKKKKKER 940
+LR+ + +K R
Sbjct: 1787 QLRSQESDRKFR 1798
Score = 38.5 bits (88), Expect = 0.040
Identities = 74/344 (21%), Positives = 142/344 (41%), Gaps = 37/344 (10%)
Query: 809 RNYAEMREKLRLRLTKR--KEEQPKKMDQ----ISERESVVDHRRVEDLLQFINSSETKP 862
R + E ++LR + ++ ++E+ +K + + ERE HR+ D +F+ E
Sbjct: 1595 RKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDR-KFLE--EEPQ 1651
Query: 863 VSSTRAAKRARH-KQRKLEEKARLEAEARAREHLHLQEEQRRREEEEDE---EEEEDRFK 918
+ ++ RH + RK E+ +L E ++ L QE R+ EEE + +E E +F
Sbjct: 1652 LRRQEREQQLRHDRDRKFREEEQLLQEGEEQQ-LRRQERDRKFREEEQQLRRQERERKFL 1710
Query: 919 EEFQRLQELQKLRAVKKKKKERPSKDCPKLDMLTRNFQAATESVPNSGNIHNGSLEQTEE 978
+E Q+L+ + R +++++ R + +L R + E Q +
Sbjct: 1711 QEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERD 1770
Query: 979 PETSSHSPSRHMNHSEPRPGLGADGDAADPV---DTRDSKFLLPKEVNGK---QHEPLSF 1032
+ R + +D + R+ + L P++ +GK + E L
Sbjct: 1771 RKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQ- 1829
Query: 1033 FFDIMQHHKEGNGKQKLRQTSKASSEPARRPTEPPKATEGQSKPRAQTESKAKVVDLMSI 1092
+ Q ++ +Q + A+ E +RR E E + K R + E K + +
Sbjct: 1830 LEEQEQRLRQERDRQYRAEEQFATQEKSRR-EEQELWQEEEQKRRQERERKLREEHIR-- 1886
Query: 1093 TEQKREERKVNSNNNNKKQLNHIKDE--KSNPTPMEPTSPGEHQ 1134
+QK E+R +Q+ IK + K + +E PG HQ
Sbjct: 1887 RQQKEEQR--------HRQVGEIKSQEGKGHGRLLE---PGTHQ 1919
Score = 38.1 bits (87), Expect = 0.052
Identities = 63/378 (16%), Positives = 143/378 (37%), Gaps = 39/378 (10%)
Query: 809 RNYAEMREKLRLRLTKRKEEQPKKMDQISERESVVDHRRVEDLLQFINSSETKPVSSTRA 868
R +E++ + R ++++E+ ++ D + ++ R L + RA
Sbjct: 741 RRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRA 800
Query: 869 AKRARHKQRKLEEKARLEAEARAR-------EHLHLQEEQRRREEEEDEEEEEDRFKEEF 921
+R + +QR L E+ E R R + L +E+ +RRE + +EEED +E+
Sbjct: 801 EERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQ 860
Query: 922 QRLQELQKLRAVK--------KKKKERPSKDCPKLDMLTRNFQAATESVPNSGNIHNGSL 973
+R + ++ R K +K++ P L R Q +
Sbjct: 861 ERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREK 920
Query: 974 EQTEEPETSSHSPSRHMNHSEPRPGLGADGDAADPVDTRDSKFLLPKEVNGKQHEPLSFF 1033
+ +E E + E L + R+ ++ K++ K+ + L
Sbjct: 921 RRRQEQERQYREEEQLQQEEEQ---LLREEREKRRRQERERQYRKDKKLQQKEEQLLG-- 975
Query: 1034 FDIMQHHKEGNGKQKLRQTSKASSEP---ARRPTEPPKATEGQSKPRAQTESKAKVVDLM 1090
+ + + ++K R+ + E R E + E + + R + E + + L+
Sbjct: 976 -EEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLL 1034
Query: 1091 SITEQKREERKVNSNNNNKKQLNHIKDEKSNPTPMEPTS------------PGEHQQNSK 1138
++RE+R++ ++ ++ E+ E + E QQ +
Sbjct: 1035 ---REEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEE 1091
Query: 1139 LVLAESPQPKGKNKKNKK 1156
+L E P+ + + ++ ++
Sbjct: 1092 QLLREEPEKRRRQERERQ 1109
Score = 37.7 bits (86), Expect = 0.068
Identities = 28/129 (21%), Positives = 66/129 (51%), Gaps = 5/129 (3%)
Query: 809 RNYAEMREKLRLRLTKRKEEQPKKMDQISERESVVDHRRVEDLLQFINSSETKPVSSTRA 868
R E EK R +R+ E + ++ + R+ + +R + Q+ +++ +
Sbjct: 730 RRRQEQEEKRR----RRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLS 785
Query: 869 AKRARHKQRKLEEKARLEAEARAREHLHLQEEQRRREEEEDEEEEEDRFKEEFQRLQELQ 928
A+ +QR+ + +A E + R + L +EE+ +R + E E+E +F EE ++LQ +
Sbjct: 786 ARPPLREQRERQLRAE-ERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRE 844
Query: 929 KLRAVKKKK 937
+ + +++++
Sbjct: 845 RAQQLQEEE 853
Score = 33.5 bits (75), Expect = 1.3
Identities = 40/161 (24%), Positives = 72/161 (44%), Gaps = 22/161 (13%)
Query: 812 AEMREKLRLRLTKRKEEQPKKMDQISERESVVDHRRVEDLLQFINSSETKPVSSTRAAKR 871
A+ R+ +++E Q ++ +Q +R RR E LQ+ +R
Sbjct: 712 ADARQSKVYSRPRKQEGQRRRQEQEEKR------RRRESELQWQEEERAHRQQQEEEQRR 765
Query: 872 ARHKQRKLEEKA-----RLEAEARAREHLHLQ---EEQRRREEE--EDEEEEEDRFKE-- 919
Q + EEK+ RL A RE Q EE+++RE+ +EEE+E R ++
Sbjct: 766 DFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRR 825
Query: 920 ----EFQRLQELQKLRAVKKKKKERPSKDCPKLDMLTRNFQ 956
E Q L+E ++L+ ++ ++ + +D + D R Q
Sbjct: 826 EREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQ 866
Score = 32.3 bits (72), Expect = 2.8
Identities = 61/341 (17%), Positives = 133/341 (39%), Gaps = 27/341 (7%)
Query: 795 EFFGHGGPPAAPTSRNYAEMREKLRLRLTKRKEEQPKKMDQISERESVVDHRRVE--DLL 852
++ H AA T ++ + E+ R+ PK +D I E + + RV+ + L
Sbjct: 17 QYVSHDCDGAALTKKDLKNLLER-EFGAVLRRPHDPKTVDLILELLDLDSNGRVDFNEFL 75
Query: 853 QFINSSETKPVSSTRAAKRARHKQRKLEE--KARLEAEARAREHLHLQEEQRR---REEE 907
FI +A A + L+E +AR + + + +E+QRR R+ +
Sbjct: 76 LFI-------FKVAQACYYALGQATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQ 128
Query: 908 EDEEEEEDRFKEEFQRLQELQKLRAVKKKKKERPSKDCPKLD----MLTRNFQAATESVP 963
+EE + R ++ ++ +EL + +K++ +D + D + +Q E
Sbjct: 129 LEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRA 188
Query: 964 NSGNIHNGSLEQTEEPETSSHSPSRHMNHSEPRPGLGADGDAADPVDTRDSKFLLPKEVN 1023
+ + +TEE R + + G + + +D F +E
Sbjct: 189 EEEQLQSCKGHETEEFPDEEQLRRRELLELRRK---GREEKQQQRRERQDRVFQEEEEKE 245
Query: 1024 GKQHEPLSFFFDIMQHHKEGNGKQKLRQTSKASSEPARRPTEPPKATEGQSKPRAQTESK 1083
++ E + + +E +++L++ + + R+ + E Q + R + E +
Sbjct: 246 WRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQ 305
Query: 1084 AKVVDLMSITEQKRE-----ERKVNSNNNNKKQLNHIKDEK 1119
+ EQ+ E ER+ ++QL ++E+
Sbjct: 306 LRRKQEEERREQQEERREQQERREQQEERREQQLRREQEER 346
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 57.0 bits (136), Expect = 1e-07
Identities = 87/382 (22%), Positives = 158/382 (41%), Gaps = 50/382 (13%)
Query: 826 KEEQPKKMDQISERESVVDHRRVEDLLQFINSSETKPVSSTRAAKRARHKQRKLEEKARL 885
KEEQ + + R+S +V+ ++++S E++PV+ R K+ EE+
Sbjct: 1020 KEEQEILSTRANSRQSPA---KVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEE 1076
Query: 886 EAEARAREHLHLQEEQRRREEEEDEEEEEDRFKEEFQRLQELQKLRAVKKK-----KKER 940
+ E E ++E+ EEEE EEEE+ + RL + Q + A+K+K KK+R
Sbjct: 1077 DEEEEEEEEEEEEDEEEEEEEEE--EEEEENIQSSPPRLTKPQSV-AIKRKRPFVLKKKR 1133
Query: 941 PSKDCPKLDMLTRNFQAATESVPNSGNIHNGSLEQTEEPETSSHSPSRHMNHSEPRPGLG 1000
K N TE++ + + N + ++E R M EP +
Sbjct: 1134 GRK------RRRINSSVTTETISETTEVLNEPFDNSDE--------ERPMPQLEPTCEIE 1179
Query: 1001 ADGDAADPV-----DTRDSKFLLPKEVNGKQHEPLSFFFDIMQHHKEGNGKQKLRQTSKA 1055
+ D PV + K +E GK + F + + L++ SK
Sbjct: 1180 VEEDGRKPVLRKAFQHQPGKKRQTEEEEGKDNH--CFKNADPCRNNMNDDSSNLKEGSKD 1237
Query: 1056 SSEPARRPTEPPKATE-GQSKPRAQTESKAKV-VDLMSITEQKREERKVNSNNNNKKQLN 1113
+ EP + PK T+ G SK R E K ++L + E E + + K+
Sbjct: 1238 NPEPLKCKQVWPKGTKRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKE--- 1294
Query: 1114 HIKDEKSNPTPMEPTSPGEHQQNSKLVLAESPQPKGKNKKNKKKKGDRVNNS-----IDD 1168
+ K++P+P+ E ++ + +L P+ +N++ + N S DD
Sbjct: 1295 -TSEGKTSPSPIRIEE--EVKETGEALL-----PQEENRREETCAPVSPNTSPGEKPEDD 1346
Query: 1169 VFLPKDIDLDSVDMDETEREVE 1190
+ P++ + + + +E E E E
Sbjct: 1347 LIKPEEEEEEEEEEEEEEEEEE 1368
Score = 40.4 bits (93), Expect = 0.010
Identities = 48/201 (23%), Positives = 73/201 (36%), Gaps = 37/201 (18%)
Query: 898 QEEQRRREEEEDEEEEEDRFKEEFQRLQELQKLRAVKKKKKERPSKDCPKLDMLTRNFQA 957
+EE+ EEEE+EEEEE+ +EE E + K ++KE P K D
Sbjct: 1351 EEEEEEEEEEEEEEEEEEGEEEEGGGNVE-KDPDGAKSQEKEEPEISTEKED-------- 1401
Query: 958 ATESVPNSGNIHNGSLEQTEEPETSSHSPSRHMNHSEPRPGLGADGDAADPVDTRDSKFL 1017
+ L+ EE E PS + +H D D + K
Sbjct: 1402 ------------SARLDDHEEEEEEDEEPSHNEDHD------ADDEDDSHMESAEVEKEE 1443
Query: 1018 LPKEVNGKQHEPLSFFFDIMQHHKEGNGKQKL----RQTSKASSEPARRPTEPPKATEGQ 1073
LP+E + E F D+ N + + T+ +SEP +P E
Sbjct: 1444 LPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDPEAVPESD 1503
Query: 1074 SKP------RAQTESKAKVVD 1088
+P + Q + +K VD
Sbjct: 1504 EEPPPGEQAQKQDQKNSKEVD 1524
Score = 31.2 bits (69), Expect = 6.3
Identities = 43/229 (18%), Positives = 83/229 (36%), Gaps = 29/229 (12%)
Query: 905 EEEEDEEEEEDRFKEEFQRLQELQKLRAVKKKKKERPSKDCPKLDMLTRNFQAATESVPN 964
EE E E+E E ++ +E Q++ + + ++ P+K K + + ES P
Sbjct: 1000 EEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSK-----NKYLHSPESRPV 1054
Query: 965 SGN-------IHNGSLEQTEEPETSSHSPSRHMNHSEPRPGLGADGDAADPVDTRDSKFL 1017
+G S E+ EE + E + + + + + +
Sbjct: 1055 TGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLT 1114
Query: 1018 LPKEVNGKQHEPLSFFFDIMQHHKEGNGKQKLRQTSKASSEPARRPTE---PPKATEGQS 1074
P+ V K+ P K+ G+++ R S ++E TE P +
Sbjct: 1115 KPQSVAIKRKRPFVL--------KKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEE 1166
Query: 1075 KPRAQTESKAKVVDLMSITEQKREE--RKVNSNNNNKKQLNHIKDEKSN 1121
+P Q E ++ + E R+ RK + KK+ ++ K N
Sbjct: 1167 RPMPQLEPTCEI----EVEEDGRKPVLRKAFQHQPGKKRQTEEEEGKDN 1211
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform 9
[Homo sapiens]
Length = 771
Score = 56.6 bits (135), Expect = 1e-07
Identities = 76/381 (19%), Positives = 152/381 (39%), Gaps = 69/381 (18%)
Query: 813 EMREKLRLRLTKRKEEQPKKMDQISERESVVDH----------RRVEDLLQFINSSETKP 862
E EK ++ K +++ K D + E E + DH R ED ++ +
Sbjct: 25 EQEEKAEIKRLKNSDDRDSKRDSLEEGE-LRDHCMEITIRNSPYRREDSMEDRGEED--- 80
Query: 863 VSSTRAAKRARHKQRKLEEKARLEAEARAREHLHLQEEQRRREEEEDEEEEEDRFKEEFQ 922
+ A K + RK + R + + + ++H ++E++R E + EE+D+ + E++
Sbjct: 81 --DSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWE 138
Query: 923 -----------------RLQELQKLRAVKKKKKERPSKDCPKLDMLTRNFQAATESVPNS 965
RL++L++ R ++K +E+ + + + R +A
Sbjct: 139 RQKRREMAREHSRRERDRLEQLERKRERERKMREQQKE---QREQKERERRAEERRKERE 195
Query: 966 GNIHNGSLEQTEEPETSSHSPSRHMNHSEPRPGLGAD--GDAADPVDTRDSKFLLPKEVN 1023
+ +T + S + H + S PRP GD PV KE
Sbjct: 196 ARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPV----------KEEK 245
Query: 1024 GKQHEPLSFFFDIMQHHKEGNGKQKLRQTSKASSEPARRPTEPPKATEGQSKPRAQTESK 1083
++ + LS DI R+TS A S A E +E + + + E +
Sbjct: 246 MEERDLLSDLQDISDSE---------RKTSSAESSSA----ESGSGSEEEEEEEEEEEEE 292
Query: 1084 AKVVDLMSITEQKREERKVNSNNNNKKQLNHIKDEKSNPTPMEPTSPGEHQQNSK--LVL 1141
+ E++ EE + + +N+++ +E S E S E ++N LV+
Sbjct: 293 GSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSE----EEMSEDEERENENHLLVV 348
Query: 1142 AES--PQPKGKNKKNKKKKGD 1160
ES + G++++ +++ G+
Sbjct: 349 PESRFDRDSGESEEAEEEVGE 369
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 56.6 bits (135), Expect = 1e-07
Identities = 100/423 (23%), Positives = 163/423 (38%), Gaps = 80/423 (18%)
Query: 652 KEDHRHSAPAAPRNSPTGLAPLPALSPAALSPAALSPASTPHLANLAAPSFPKTATTTPG 711
+E+ + + A S LPA A LS + S S + A PS P T+ P
Sbjct: 422 RENEKEKSALARERSLKKRQSLPASPRARLSASTASELSPK---SKARPSSPSTSWHRPA 478
Query: 712 FVDTRKSFCPAP--------LPPATDGSISAPPS-VCSDPDCEGHRCENGVYDPQQDDGD 762
S CP+P PP+ G+ ++P V + + G D Q
Sbjct: 479 ------SPCPSPGPGHTLPPKPPSPRGTTASPKGRVRRKEEAKESPSAAGPEDKSQSKRR 532
Query: 763 ESADEDSCSEHSSSTSTSTN------QKEGKYC----DCCYCEFFGHGGPPAAPTS--RN 810
S +++S + S + S + + QKE D PP P+
Sbjct: 533 ASNEKESAAPASPAPSPAPSPTPAPPQKEQPPAETPTDAAVLTSPPAPAPPVTPSKPMAG 592
Query: 811 YAEMREKLRLRLTKRKE--EQPKKMDQISERESVVDHRRVEDLLQFINSSETKPVSSTRA 868
+ E RL KR++ EQ ++ +Q ++ D R E+ Q +E +
Sbjct: 593 TTDREEATRLLAEKRRQAREQREREEQERRLQAERDKRMREE--QLAREAEAR------- 643
Query: 869 AKRARHKQRKLEEKARLEAEARAREHLHLQEEQRRREEEEDEEEEEDRFKEEFQRL---- 924
A+R +R+ E++AR +A+A QEEQ R +++++E E R + E QRL
Sbjct: 644 AEREAEARRREEQEAREKAQAE-------QEEQERLQKQKEEAEARSREEAERQRLEREK 696
Query: 925 ------QELQKLR-----AVKKKKKERPSKDCPKLDMLTRNFQAATESVPNSGNIHNGSL 973
QE Q+ R +K+ +K S+ K D N ++ + + L
Sbjct: 697 HFQQQEQERQERRKRLEEIMKRTRKSEVSETKQKQDSKEANANGSSPEPVKAVEARSPGL 756
Query: 974 E----QTEEP--------ETSSHSPSRHMNHSEPRP-----GLGADGDAADPVDTRDSKF 1016
+ Q EEP S P+ +N +P P G +G + D +R +
Sbjct: 757 QKEAVQKEEPIPQEPQWSLPSKELPASLVNGLQPLPAHQENGFSTNGPSGDKSLSRTPET 816
Query: 1017 LLP 1019
LLP
Sbjct: 817 LLP 819
Score = 33.5 bits (75), Expect = 1.3
Identities = 23/73 (31%), Positives = 37/73 (50%), Gaps = 1/73 (1%)
Query: 857 SSETKPVSSTRAAKRARHKQRKLEEKARLEAEARAREHLHLQEEQRRREEEEDEEEEEDR 916
+ E ++ R +RA++ K E +A+A LQE +RR EE+ + E+
Sbjct: 135 AGERHKLAKERREERAKYLAAKKAVWLEKEEKAKALREKQLQERRRRLEEQRLKAEQRRA 194
Query: 917 FKEEFQRLQELQK 929
EE QR Q+L+K
Sbjct: 195 ALEERQR-QKLEK 206
Score = 32.0 bits (71), Expect = 3.7
Identities = 24/92 (26%), Positives = 51/92 (55%), Gaps = 6/92 (6%)
Query: 855 INSSETKPVSSTRAAKRARHKQRK--LEEKARLEAEARAREHLHLQEEQRRREEEEDEEE 912
+ +S++ P RHK K EE+A+ A A++ + L++E++ + E + +
Sbjct: 120 VPASDSPPTKQEVKKAGERHKLAKERREERAKYLA---AKKAVWLEKEEKAKALREKQLQ 176
Query: 913 EEDRFKEEFQRLQELQKLRAVKKKKKERPSKD 944
E R EE QRL+ Q+ A++++++++ K+
Sbjct: 177 ERRRRLEE-QRLKAEQRRAALEERQRQKLEKN 207
>gi|12751473 DNA cytosine methyltransferase 3 alpha isoform a [Homo
sapiens]
Length = 912
Score = 56.2 bits (134), Expect = 2e-07
Identities = 68/282 (24%), Positives = 108/282 (38%), Gaps = 42/282 (14%)
Query: 901 QRRREEEEDEEEEEDRFKEEFQRLQEL-QKLRAVKKKKKERP--SKDCPKLDMLTRNFQA 957
+R + ++ EE+EE R KEE Q +K+ +K+K P S D PK + +
Sbjct: 18 EREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPVESGDTPKDPAVISKSPS 77
Query: 958 ATESVPNSGNIHNGSLEQTEEPETSSHSPSRHMNHSEPRPGLGADGDAADPVDTRDSKFL 1017
+ S + NG LE+ EP+ SP+ P G GA + ++
Sbjct: 78 MAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEGEGAAETLPEASRAVENGCC 137
Query: 1018 LPKEVNGK-----QHEPLSFFFDIMQHHKEGNGKQKLRQTSKASSEPARRPT-------- 1064
PKE G + + + + G + L S P R T
Sbjct: 138 TPKEGRGAPAEAGKEQKETNIESMKMEGSRGRLRGGLGWESSLRQRPMPRLTFQAGDPYY 197
Query: 1065 -EPPKATEGQSKPRAQTESKAKVVDLMSITEQKR---EERKVNSNNNNKKQLNHIKDEKS 1120
K E ++ + + E KAKV+ M+ E+ + E +KV +E S
Sbjct: 198 ISKRKRDEWLARWKREAEKKAKVIAGMNAVEENQGPGESQKV--------------EEAS 243
Query: 1121 NPTPMEPTSPGEHQQNSKLVLAESPQPKGKN--KKNKKKKGD 1160
P +PT P + +A +P+P G + KN K GD
Sbjct: 244 PPAVQQPTDP------ASPTVATTPEPVGSDAGDKNATKAGD 279
>gi|28559069 DNA cytosine methyltransferase 3 alpha isoform a [Homo
sapiens]
Length = 912
Score = 56.2 bits (134), Expect = 2e-07
Identities = 68/282 (24%), Positives = 108/282 (38%), Gaps = 42/282 (14%)
Query: 901 QRRREEEEDEEEEEDRFKEEFQRLQEL-QKLRAVKKKKKERP--SKDCPKLDMLTRNFQA 957
+R + ++ EE+EE R KEE Q +K+ +K+K P S D PK + +
Sbjct: 18 EREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPVESGDTPKDPAVISKSPS 77
Query: 958 ATESVPNSGNIHNGSLEQTEEPETSSHSPSRHMNHSEPRPGLGADGDAADPVDTRDSKFL 1017
+ S + NG LE+ EP+ SP+ P G GA + ++
Sbjct: 78 MAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEGEGAAETLPEASRAVENGCC 137
Query: 1018 LPKEVNGK-----QHEPLSFFFDIMQHHKEGNGKQKLRQTSKASSEPARRPT-------- 1064
PKE G + + + + G + L S P R T
Sbjct: 138 TPKEGRGAPAEAGKEQKETNIESMKMEGSRGRLRGGLGWESSLRQRPMPRLTFQAGDPYY 197
Query: 1065 -EPPKATEGQSKPRAQTESKAKVVDLMSITEQKR---EERKVNSNNNNKKQLNHIKDEKS 1120
K E ++ + + E KAKV+ M+ E+ + E +KV +E S
Sbjct: 198 ISKRKRDEWLARWKREAEKKAKVIAGMNAVEENQGPGESQKV--------------EEAS 243
Query: 1121 NPTPMEPTSPGEHQQNSKLVLAESPQPKGKN--KKNKKKKGD 1160
P +PT P + +A +P+P G + KN K GD
Sbjct: 244 PPAVQQPTDP------ASPTVATTPEPVGSDAGDKNATKAGD 279
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 55.8 bits (133), Expect = 2e-07
Identities = 40/141 (28%), Positives = 72/141 (51%), Gaps = 6/141 (4%)
Query: 809 RNYAEMREKLRLRLTKRKEEQPKKMDQISERESVVDHRRVEDLLQFINSSETKPVSSTRA 868
R AEMR K KR+EE ++ ++I R+ + +R E+ + + + + R
Sbjct: 735 RREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE-ELARRKQEEALRRQRE 793
Query: 869 AKRARHKQRKLEEKARLEAEARAREHLHLQEEQRRREEEEDEEEEED-----RFKEEFQR 923
+ A +QR+ EE+ + E R E +EE+RR++EE ++EE+ R +EE QR
Sbjct: 794 QEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQR 853
Query: 924 LQELQKLRAVKKKKKERPSKD 944
E +LR ++ + R ++
Sbjct: 854 RLEENRLRMEEEAARLRHEEE 874
Score = 45.4 bits (106), Expect = 3e-04
Identities = 37/160 (23%), Positives = 75/160 (46%), Gaps = 11/160 (6%)
Query: 819 RLRLTKRKEEQPKKMDQISERESVVDHRRVEDLLQFINSSETKPVSSTRAAKRARHKQRK 878
R R + +++Q + + ++ ER + RR ++ L E + + A+ QR+
Sbjct: 800 RQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEE-----AAKWAREEEEAQRR 854
Query: 879 LEEKARLEAEARAREHLHLQEEQRRREEEEDEEEEEDRFKEEFQRLQELQKLRAVKKKKK 938
LEE RL E A H +EE++R+E E ++E R QR Q+ + LR ++++++
Sbjct: 855 LEEN-RLRMEEEAARLRHEEEERKRKELEVQRQKELMR-----QRQQQQEALRRLQQQQQ 908
Query: 939 ERPSKDCPKLDMLTRNFQAATESVPNSGNIHNGSLEQTEE 978
++ T Q+ T + + + +++ EE
Sbjct: 909 QQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEE 948
Score = 37.7 bits (86), Expect = 0.068
Identities = 57/311 (18%), Positives = 119/311 (38%), Gaps = 32/311 (10%)
Query: 852 LQFINSSETKPVSSTRAAKRARHKQRKLEEKARLEAEARAREHLHLQEEQRRREEEEDE- 910
LQ + ++ + R R K+ + E K + E + E L Q+E+ R+ EE+E
Sbjct: 720 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEEL 779
Query: 911 ---EEEE------------DRFKEEFQRLQELQKLRAVKKKKKERPSKDCPKLDMLTRNF 955
++EE R +EE +R Q+ + LR ++++++E + K + L R
Sbjct: 780 ARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEER--RKQEELLRKQ 837
Query: 956 QAATESVPNSGNIHNGSLEQTEEPETSSHSPSRHMNHSEPRPGLGADGDAADPVDTRDSK 1015
+ LE+ + RH R L + +
Sbjct: 838 EEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQ 897
Query: 1016 FLLPKEVNGKQHEPLSFFFDIMQHHKEGNGKQKLRQTSKASSEPARRPTEPPKATEGQSK 1075
L + +Q + L+ + G+Q T+ S+ E K E + +
Sbjct: 898 EALRRLQQQQQQQQLA---QMKLPSSSTWGQQS--NTTACQSQATLSLAEIQKLEEERER 952
Query: 1076 PRAQTESKAKVVDLMSITEQKREERK--------VNSNNNNKKQLNHIKDEKSNPTPMEP 1127
+ + E + + +LM +Q++++++ V+ + K L I+ E++ +
Sbjct: 953 -QLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQ 1011
Query: 1128 TSPGEHQQNSK 1138
+HQQ ++
Sbjct: 1012 QQQQQHQQPNR 1022
Score = 36.2 bits (82), Expect = 0.20
Identities = 30/115 (26%), Positives = 54/115 (46%), Gaps = 13/115 (11%)
Query: 838 ERESVVDHRRVEDLLQFINSSETKPVSSTRAAKRARHKQRKLEE--KARLEAEARAREHL 895
E+ ++ + L Q +E + KR +R+ EE + + E E + RE
Sbjct: 718 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 777
Query: 896 HL----QEEQRRREEEED-------EEEEEDRFKEEFQRLQELQKLRAVKKKKKE 939
L QEE RR+ E++ EEEE + +E +RL+E ++ ++K++E
Sbjct: 778 ELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE 832
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 55.8 bits (133), Expect = 2e-07
Identities = 40/141 (28%), Positives = 72/141 (51%), Gaps = 6/141 (4%)
Query: 809 RNYAEMREKLRLRLTKRKEEQPKKMDQISERESVVDHRRVEDLLQFINSSETKPVSSTRA 868
R AEMR K KR+EE ++ ++I R+ + +R E+ + + + + R
Sbjct: 762 RREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE-ELARRKQEEALRRQRE 820
Query: 869 AKRARHKQRKLEEKARLEAEARAREHLHLQEEQRRREEEEDEEEEED-----RFKEEFQR 923
+ A +QR+ EE+ + E R E +EE+RR++EE ++EE+ R +EE QR
Sbjct: 821 QEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQR 880
Query: 924 LQELQKLRAVKKKKKERPSKD 944
E +LR ++ + R ++
Sbjct: 881 RLEENRLRMEEEAARLRHEEE 901
Score = 45.4 bits (106), Expect = 3e-04
Identities = 37/160 (23%), Positives = 75/160 (46%), Gaps = 11/160 (6%)
Query: 819 RLRLTKRKEEQPKKMDQISERESVVDHRRVEDLLQFINSSETKPVSSTRAAKRARHKQRK 878
R R + +++Q + + ++ ER + RR ++ L E + + A+ QR+
Sbjct: 827 RQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEE-----AAKWAREEEEAQRR 881
Query: 879 LEEKARLEAEARAREHLHLQEEQRRREEEEDEEEEEDRFKEEFQRLQELQKLRAVKKKKK 938
LEE RL E A H +EE++R+E E ++E R QR Q+ + LR ++++++
Sbjct: 882 LEEN-RLRMEEEAARLRHEEEERKRKELEVQRQKELMR-----QRQQQQEALRRLQQQQQ 935
Query: 939 ERPSKDCPKLDMLTRNFQAATESVPNSGNIHNGSLEQTEE 978
++ T Q+ T + + + +++ EE
Sbjct: 936 QQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEE 975
Score = 37.7 bits (86), Expect = 0.068
Identities = 57/311 (18%), Positives = 119/311 (38%), Gaps = 32/311 (10%)
Query: 852 LQFINSSETKPVSSTRAAKRARHKQRKLEEKARLEAEARAREHLHLQEEQRRREEEEDE- 910
LQ + ++ + R R K+ + E K + E + E L Q+E+ R+ EE+E
Sbjct: 747 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEEL 806
Query: 911 ---EEEE------------DRFKEEFQRLQELQKLRAVKKKKKERPSKDCPKLDMLTRNF 955
++EE R +EE +R Q+ + LR ++++++E + K + L R
Sbjct: 807 ARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEER--RKQEELLRKQ 864
Query: 956 QAATESVPNSGNIHNGSLEQTEEPETSSHSPSRHMNHSEPRPGLGADGDAADPVDTRDSK 1015
+ LE+ + RH R L + +
Sbjct: 865 EEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQ 924
Query: 1016 FLLPKEVNGKQHEPLSFFFDIMQHHKEGNGKQKLRQTSKASSEPARRPTEPPKATEGQSK 1075
L + +Q + L+ + G+Q T+ S+ E K E + +
Sbjct: 925 EALRRLQQQQQQQQLA---QMKLPSSSTWGQQS--NTTACQSQATLSLAEIQKLEEERER 979
Query: 1076 PRAQTESKAKVVDLMSITEQKREERK--------VNSNNNNKKQLNHIKDEKSNPTPMEP 1127
+ + E + + +LM +Q++++++ V+ + K L I+ E++ +
Sbjct: 980 -QLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQ 1038
Query: 1128 TSPGEHQQNSK 1138
+HQQ ++
Sbjct: 1039 QQQQQHQQPNR 1049
Score = 36.2 bits (82), Expect = 0.20
Identities = 30/115 (26%), Positives = 54/115 (46%), Gaps = 13/115 (11%)
Query: 838 ERESVVDHRRVEDLLQFINSSETKPVSSTRAAKRARHKQRKLEE--KARLEAEARAREHL 895
E+ ++ + L Q +E + KR +R+ EE + + E E + RE
Sbjct: 745 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 804
Query: 896 HL----QEEQRRREEEED-------EEEEEDRFKEEFQRLQELQKLRAVKKKKKE 939
L QEE RR+ E++ EEEE + +E +RL+E ++ ++K++E
Sbjct: 805 ELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE 859
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 55.8 bits (133), Expect = 2e-07
Identities = 40/141 (28%), Positives = 72/141 (51%), Gaps = 6/141 (4%)
Query: 809 RNYAEMREKLRLRLTKRKEEQPKKMDQISERESVVDHRRVEDLLQFINSSETKPVSSTRA 868
R AEMR K KR+EE ++ ++I R+ + +R E+ + + + + R
Sbjct: 741 RREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE-ELARRKQEEALRRQRE 799
Query: 869 AKRARHKQRKLEEKARLEAEARAREHLHLQEEQRRREEEEDEEEEED-----RFKEEFQR 923
+ A +QR+ EE+ + E R E +EE+RR++EE ++EE+ R +EE QR
Sbjct: 800 QEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQR 859
Query: 924 LQELQKLRAVKKKKKERPSKD 944
E +LR ++ + R ++
Sbjct: 860 RLEENRLRMEEEAARLRHEEE 880
Score = 45.4 bits (106), Expect = 3e-04
Identities = 37/160 (23%), Positives = 75/160 (46%), Gaps = 11/160 (6%)
Query: 819 RLRLTKRKEEQPKKMDQISERESVVDHRRVEDLLQFINSSETKPVSSTRAAKRARHKQRK 878
R R + +++Q + + ++ ER + RR ++ L E + + A+ QR+
Sbjct: 806 RQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEE-----AAKWAREEEEAQRR 860
Query: 879 LEEKARLEAEARAREHLHLQEEQRRREEEEDEEEEEDRFKEEFQRLQELQKLRAVKKKKK 938
LEE RL E A H +EE++R+E E ++E R QR Q+ + LR ++++++
Sbjct: 861 LEEN-RLRMEEEAARLRHEEEERKRKELEVQRQKELMR-----QRQQQQEALRRLQQQQQ 914
Query: 939 ERPSKDCPKLDMLTRNFQAATESVPNSGNIHNGSLEQTEE 978
++ T Q+ T + + + +++ EE
Sbjct: 915 QQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEE 954
Score = 37.7 bits (86), Expect = 0.068
Identities = 57/311 (18%), Positives = 119/311 (38%), Gaps = 32/311 (10%)
Query: 852 LQFINSSETKPVSSTRAAKRARHKQRKLEEKARLEAEARAREHLHLQEEQRRREEEEDE- 910
LQ + ++ + R R K+ + E K + E + E L Q+E+ R+ EE+E
Sbjct: 726 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEEL 785
Query: 911 ---EEEE------------DRFKEEFQRLQELQKLRAVKKKKKERPSKDCPKLDMLTRNF 955
++EE R +EE +R Q+ + LR ++++++E + K + L R
Sbjct: 786 ARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEER--RKQEELLRKQ 843
Query: 956 QAATESVPNSGNIHNGSLEQTEEPETSSHSPSRHMNHSEPRPGLGADGDAADPVDTRDSK 1015
+ LE+ + RH R L + +
Sbjct: 844 EEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQ 903
Query: 1016 FLLPKEVNGKQHEPLSFFFDIMQHHKEGNGKQKLRQTSKASSEPARRPTEPPKATEGQSK 1075
L + +Q + L+ + G+Q T+ S+ E K E + +
Sbjct: 904 EALRRLQQQQQQQQLA---QMKLPSSSTWGQQS--NTTACQSQATLSLAEIQKLEEERER 958
Query: 1076 PRAQTESKAKVVDLMSITEQKREERK--------VNSNNNNKKQLNHIKDEKSNPTPMEP 1127
+ + E + + +LM +Q++++++ V+ + K L I+ E++ +
Sbjct: 959 -QLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQ 1017
Query: 1128 TSPGEHQQNSK 1138
+HQQ ++
Sbjct: 1018 QQQQQHQQPNR 1028
Score = 36.2 bits (82), Expect = 0.20
Identities = 30/115 (26%), Positives = 54/115 (46%), Gaps = 13/115 (11%)
Query: 838 ERESVVDHRRVEDLLQFINSSETKPVSSTRAAKRARHKQRKLEE--KARLEAEARAREHL 895
E+ ++ + L Q +E + KR +R+ EE + + E E + RE
Sbjct: 724 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 783
Query: 896 HL----QEEQRRREEEED-------EEEEEDRFKEEFQRLQELQKLRAVKKKKKE 939
L QEE RR+ E++ EEEE + +E +RL+E ++ ++K++E
Sbjct: 784 ELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE 838
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 55.8 bits (133), Expect = 2e-07
Identities = 40/141 (28%), Positives = 72/141 (51%), Gaps = 6/141 (4%)
Query: 809 RNYAEMREKLRLRLTKRKEEQPKKMDQISERESVVDHRRVEDLLQFINSSETKPVSSTRA 868
R AEMR K KR+EE ++ ++I R+ + +R E+ + + + + R
Sbjct: 741 RREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE-ELARRKQEEALRRQRE 799
Query: 869 AKRARHKQRKLEEKARLEAEARAREHLHLQEEQRRREEEEDEEEEED-----RFKEEFQR 923
+ A +QR+ EE+ + E R E +EE+RR++EE ++EE+ R +EE QR
Sbjct: 800 QEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQR 859
Query: 924 LQELQKLRAVKKKKKERPSKD 944
E +LR ++ + R ++
Sbjct: 860 RLEENRLRMEEEAARLRHEEE 880
Score = 45.4 bits (106), Expect = 3e-04
Identities = 37/160 (23%), Positives = 75/160 (46%), Gaps = 11/160 (6%)
Query: 819 RLRLTKRKEEQPKKMDQISERESVVDHRRVEDLLQFINSSETKPVSSTRAAKRARHKQRK 878
R R + +++Q + + ++ ER + RR ++ L E + + A+ QR+
Sbjct: 806 RQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEE-----AAKWAREEEEAQRR 860
Query: 879 LEEKARLEAEARAREHLHLQEEQRRREEEEDEEEEEDRFKEEFQRLQELQKLRAVKKKKK 938
LEE RL E A H +EE++R+E E ++E R QR Q+ + LR ++++++
Sbjct: 861 LEEN-RLRMEEEAARLRHEEEERKRKELEVQRQKELMR-----QRQQQQEALRRLQQQQQ 914
Query: 939 ERPSKDCPKLDMLTRNFQAATESVPNSGNIHNGSLEQTEE 978
++ T Q+ T + + + +++ EE
Sbjct: 915 QQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEE 954
Score = 37.7 bits (86), Expect = 0.068
Identities = 57/311 (18%), Positives = 119/311 (38%), Gaps = 32/311 (10%)
Query: 852 LQFINSSETKPVSSTRAAKRARHKQRKLEEKARLEAEARAREHLHLQEEQRRREEEEDE- 910
LQ + ++ + R R K+ + E K + E + E L Q+E+ R+ EE+E
Sbjct: 726 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEEL 785
Query: 911 ---EEEE------------DRFKEEFQRLQELQKLRAVKKKKKERPSKDCPKLDMLTRNF 955
++EE R +EE +R Q+ + LR ++++++E + K + L R
Sbjct: 786 ARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEER--RKQEELLRKQ 843
Query: 956 QAATESVPNSGNIHNGSLEQTEEPETSSHSPSRHMNHSEPRPGLGADGDAADPVDTRDSK 1015
+ LE+ + RH R L + +
Sbjct: 844 EEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQ 903
Query: 1016 FLLPKEVNGKQHEPLSFFFDIMQHHKEGNGKQKLRQTSKASSEPARRPTEPPKATEGQSK 1075
L + +Q + L+ + G+Q T+ S+ E K E + +
Sbjct: 904 EALRRLQQQQQQQQLA---QMKLPSSSTWGQQS--NTTACQSQATLSLAEIQKLEEERER 958
Query: 1076 PRAQTESKAKVVDLMSITEQKREERK--------VNSNNNNKKQLNHIKDEKSNPTPMEP 1127
+ + E + + +LM +Q++++++ V+ + K L I+ E++ +
Sbjct: 959 -QLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQ 1017
Query: 1128 TSPGEHQQNSK 1138
+HQQ ++
Sbjct: 1018 QQQQQHQQPNR 1028
Score = 36.2 bits (82), Expect = 0.20
Identities = 30/115 (26%), Positives = 54/115 (46%), Gaps = 13/115 (11%)
Query: 838 ERESVVDHRRVEDLLQFINSSETKPVSSTRAAKRARHKQRKLEE--KARLEAEARAREHL 895
E+ ++ + L Q +E + KR +R+ EE + + E E + RE
Sbjct: 724 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 783
Query: 896 HL----QEEQRRREEEED-------EEEEEDRFKEEFQRLQELQKLRAVKKKKKE 939
L QEE RR+ E++ EEEE + +E +RL+E ++ ++K++E
Sbjct: 784 ELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE 838
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 55.8 bits (133), Expect = 2e-07
Identities = 34/125 (27%), Positives = 65/125 (52%), Gaps = 9/125 (7%)
Query: 824 KRKEEQPKKMDQISERESVVDHRRVEDLLQFINSSETKPVSSTRAAKRARHKQRKLEEKA 883
K+K+++ K+ ++ E E + E + + K + K ++ K EE+
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 884 RLEAEARAREHLHLQEEQRRREEEEDEEEEEDRFKEEFQRLQELQKLR-----AVKKKKK 938
+ + + + ++ +EE+R EEEE+EEE+E+ KEE +R ++ +K R KKKK+
Sbjct: 61 KRKRKRKKKK----EEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKR 116
Query: 939 ERPSK 943
R +K
Sbjct: 117 RRKTK 121
Score = 45.8 bits (107), Expect = 2e-04
Identities = 24/117 (20%), Positives = 57/117 (48%)
Query: 824 KRKEEQPKKMDQISERESVVDHRRVEDLLQFINSSETKPVSSTRAAKRARHKQRKLEEKA 883
K++ E+ ++ ++ E E R+ + + + K T K +++K + K
Sbjct: 7 KKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKR 66
Query: 884 RLEAEARAREHLHLQEEQRRREEEEDEEEEEDRFKEEFQRLQELQKLRAVKKKKKER 940
+ + E RE +EE+ + EEE++E + K+ ++ +E +K + ++K K++
Sbjct: 67 KKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123
Score = 33.9 bits (76), Expect = 0.98
Identities = 25/122 (20%), Positives = 49/122 (40%), Gaps = 4/122 (3%)
Query: 1041 KEGNGKQKLRQTSKASSEPARRPTEPPKATEGQSKPRAQTESKAKVVDLMSITEQKREER 1100
K+ K+K + ++ + E + K E + + R + E K K + E++ EE+
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 1101 KVNSNNNNKKQLNHIKDEKSNPTPMEPTSPGEH----QQNSKLVLAESPQPKGKNKKNKK 1156
K KK+ ++E+ + E ++ K E + K K ++ K
Sbjct: 61 KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120
Query: 1157 KK 1158
KK
Sbjct: 121 KK 122
Score = 32.3 bits (72), Expect = 2.8
Identities = 23/88 (26%), Positives = 37/88 (42%), Gaps = 6/88 (6%)
Query: 1038 QHHKEGNGKQKLRQTSKASSEPAR-RPTEPPKATEGQSKPRAQTESKAKVVDLM-----S 1091
+ KEG K+K ++ K + + + TE K E + K R + K K +
Sbjct: 22 EEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEE 81
Query: 1092 ITEQKREERKVNSNNNNKKQLNHIKDEK 1119
E+K EE K KK+ K+E+
Sbjct: 82 EEEEKEEEEKEEGRRRKKKKKRRRKEEE 109
Score = 31.6 bits (70), Expect = 4.8
Identities = 14/50 (28%), Positives = 33/50 (66%)
Query: 898 QEEQRRREEEEDEEEEEDRFKEEFQRLQELQKLRAVKKKKKERPSKDCPK 947
+++++++E EE EE EE +EE + ++ ++ K+K+K++ +K+ K
Sbjct: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEK 51
>gi|148806928 hypothetical protein LOC57482 [Homo sapiens]
Length = 1233
Score = 55.5 bits (132), Expect = 3e-07
Identities = 103/448 (22%), Positives = 172/448 (38%), Gaps = 94/448 (20%)
Query: 677 SPAALSPAALSPASTPHLANLAA--PSFPKTATTTPGFVDTRKSFCPAPLPPATDGSISA 734
+P++LSP L A + +A PS PK ++ G +++ + PL A + +A
Sbjct: 99 TPSSLSPLNLPGAGSEMEEKVAPVKPSRPKRHFSSAGTIES-VNLDAIPLAIARLDNSAA 157
Query: 735 PPSVCSDPDCE--GHRCENGVYDPQQDDG--------DESAD--EDSCSEHSSSTSTSTN 782
+ P + + DPQ + G D++ ED + H + +
Sbjct: 158 KHKLAVKPKKQRVSKKHRRLAQDPQHEQGGLESRPCLDQNGHPGEDKPTWHEEEPNPLDS 217
Query: 783 QKEGKYCDCCYCEFFGHGGPPAAPTSRNYAEMREKLRLRLTKRKEEQPKKMDQISERESV 842
++E + + + E A R AE EK RL EEQ Q ER
Sbjct: 218 EEERRRQEDYWREL-------EAKCKRQKAEAAEKRRL------EEQRL---QALERRLW 261
Query: 843 VDHRRVEDLLQFINSSETKPVSSTRAAK-----------------RARHKQRKLE---EK 882
++RR ++LL+ + P+ + RA + R R ++ +LE E+
Sbjct: 262 EENRR-QELLEEEGEGQEPPLEAERAPREEQQRSLEAPGWEDAERREREERERLEAEEER 320
Query: 883 ARLEAEARAREHLHLQEEQRRREEEEDEEEEEDRFKEEFQRLQELQKLRAVKKKKKERPS 942
RL+A+A+A E L EE R EE +EEEE R EE K+++E +
Sbjct: 321 RRLQAQAQAEERRRL-EEDARLEERRRQEEEEGRCAEEL-------------KRQEEEEA 366
Query: 943 KDCPKLDMLTRNFQAATESVPNSGNIHNGSLEQ---TEEPETSSH------SPSRHMNHS 993
+ +L+ Q E++ +G G+ E+ EE E +H S +N
Sbjct: 367 EGWEELEQQEAEVQGPPEALEETGEGRRGAEEEDLGEEEEEGQAHLEDWRGQLSELLNDF 426
Query: 994 EPRPGLGADGDAADPVDTRDSKFLLPKEVNGKQHEPLSFFFDIMQHHKEGNGKQKLRQTS 1053
E R D + L P+ EP I + +++ +Q
Sbjct: 427 EER--------------LEDQERLKPEGQREHSEEP-----GICEEQNPEAERRREQQGR 467
Query: 1054 KASSEPARRPTEPPKATEGQSKPRAQTE 1081
+ A RP K EG ++P + E
Sbjct: 468 SGDFQGADRPGPEEKREEGDTEPLLKQE 495
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 55.5 bits (132), Expect = 3e-07
Identities = 87/392 (22%), Positives = 149/392 (38%), Gaps = 66/392 (16%)
Query: 824 KRKEEQPKKMDQISERESVV--DHRRVE--------DLLQFINSSETKPVSSTRAAKRAR 873
K++EE+ + D+IS E + D R E + + I + + K ++ RA A
Sbjct: 239 KQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAE 298
Query: 874 HK-------QRKLEEKARLEAEAR--AREHLHLQEEQRRREEEEDE-EEEEDRFKEEFQR 923
K +R+ EE+ R+ E + A E ++EE++R EE +EEE R EE QR
Sbjct: 299 EKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQR 358
Query: 924 LQELQKLRAVKKKKKERPSKDCPKLDMLTRNFQAAT------------ESVPN--SGNIH 969
++E +K A ++++ ++ K++ RN Q E V G
Sbjct: 359 IKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWV 418
Query: 970 NGSLEQTEEPETS---SHSPSRHMNHSEPRPGLGADGDAADPVDTRDSKFLLPKEVNGKQ 1026
N Q ++ +T+ + R L D + +D K KE
Sbjct: 419 NEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKE----P 474
Query: 1027 HEPLSFFFDIMQ---HHKEGNGK---QKLRQTSKASSEPARRPTEPPKATEGQ------- 1073
E + F D + K NG+ KL+ T S P R + K EG
Sbjct: 475 KEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGK 534
Query: 1074 -----SKPRAQTESKAKVVDLMSITEQKREERKVNSNNNNKK--QLNHIKDEKSNPTPME 1126
+ R +TES+ +QK++E + KK + + +E+ E
Sbjct: 535 RLEELRRRRGETESEE-----FEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQE 589
Query: 1127 PTSPGEHQQNSKLVLAESPQPKGKNKKNKKKK 1158
++ K L E + + K++K
Sbjct: 590 EADRKLREEEEKRRLKEEIERRRAEAAEKRQK 621
Score = 48.5 bits (114), Expect = 4e-05
Identities = 88/370 (23%), Positives = 141/370 (38%), Gaps = 50/370 (13%)
Query: 821 RLTKRKEEQPKKMDQISERESVVDHRRVEDLLQFINSSETKPVSSTRAAKRARHKQRKLE 880
RL +R+E + K++ + ER+ D + L S ++ + + A K+ K E
Sbjct: 99 RLARREERRQKRLQEALERQKEFDPTITDASL----SLPSRRMQNDTAENETTEKEEKSE 154
Query: 881 EKA-RLEAEARAREHLHLQEEQRRREEE---EDEE-EEEDRFKEEFQRLQELQKLRAVKK 935
+ R E E Q+ R EE ED+E EEE+ K + + E Q V++
Sbjct: 155 SRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEE 214
Query: 936 KKKERPSKDCPKLDMLTRNFQAATESVPNSGNIHNGS-----LEQTEEPETSSHSPSRHM 990
K E + + M +N Q ++E GS E+ EE + R
Sbjct: 215 KTTESQEE---TVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERAR 271
Query: 991 NHSEPRPGLGADGD----------AADPVDTRDSKFLLPKEVNGKQHEPLSFFFDIMQHH 1040
+E R + A+ D A+ + E + E + Q
Sbjct: 272 LEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRI 331
Query: 1041 KE-----GNGKQKLRQTSKASSEPARRPTEPPK-ATEGQSKPRAQTESKAKVVDLMSITE 1094
KE +Q++++ K ++E +R E K A E + + RA+ E KAKV
Sbjct: 332 KEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKV-------- 383
Query: 1095 QKREERKVNSNNNNKK---QLNHIKDEKSNPTPMEPTSPGEHQQNSKL---VLAESPQPK 1148
EE+K N KK Q IK EK + Q KL VL + + K
Sbjct: 384 ---EEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEK 440
Query: 1149 GKNKKNKKKK 1158
G + K++K
Sbjct: 441 GTKVQAKREK 450
Score = 34.7 bits (78), Expect = 0.57
Identities = 72/371 (19%), Positives = 130/371 (35%), Gaps = 87/371 (23%)
Query: 870 KRARHKQRKLEEKARLEAE--------------ARAREHLHLQEEQRRREEEE------- 908
+R R +R+ E+ RLEAE AR R QE R+++EEE
Sbjct: 5 ERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTD 64
Query: 909 -----------DEE------------EEEDRFKEEFQRLQELQKLR---AVKKKKKERPS 942
DEE ++E F E R +E ++ R A++++K+ P+
Sbjct: 65 QVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPT 124
Query: 943 KDCPKLDMLTRNFQAAT-------ESVPNSGNIHNGSLEQTE------------EPETSS 983
L + +R Q T + + +E+TE + E +
Sbjct: 125 ITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENK 184
Query: 984 HSPSRHMNHSEPRPGLGADGDAADPVDTRDSKFLLPKEV------NG-------KQHEPL 1030
E +P G+ G+ V + +E NG KQ E
Sbjct: 185 KEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEER 244
Query: 1031 SFFFDIMQHHKEGNGKQKLRQTSKASSEPARRPTEPPKATEGQSKPRAQTESKAKVVDLM 1090
D + HH+ K + +A +E AR E + + + + E +A++
Sbjct: 245 EQGSDEISHHE----KMEEEDKERAEAERARLEAEERERIKAEQDKKIADE-RARIEAEE 299
Query: 1091 SITEQKREERKVNSNNNNKKQLNHIKDEKSNPTPMEPTSPGEHQ---QNSKLVLAESPQP 1147
Q+RE R+ +++ +E+ E + E Q + K E +
Sbjct: 300 KAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRI 359
Query: 1148 KGKNKKNKKKK 1158
K + K+ +++
Sbjct: 360 KEEEKRAAEER 370
Score = 32.3 bits (72), Expect = 2.8
Identities = 30/108 (27%), Positives = 55/108 (50%), Gaps = 19/108 (17%)
Query: 855 INSSETKPVSSTRAAKRARHKQR-----------KLEEKARLEAEARAREHLHLQEEQRR 903
+++ E + A KR +R KL++K + EA E +EE+R+
Sbjct: 519 VDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQ-EAALELEELKKKREERRK 577
Query: 904 REEEEDE---EEEED---RFKEEFQRL-QELQKLRAVKKKKKERPSKD 944
EEE++ +EE D R +EE +RL +E+++ RA +K+++ +D
Sbjct: 578 VLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPED 625
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform 2
[Homo sapiens]
Length = 782
Score = 55.5 bits (132), Expect = 3e-07
Identities = 82/394 (20%), Positives = 153/394 (38%), Gaps = 84/394 (21%)
Query: 813 EMREKLRLRLTKRKEEQPKKMDQISERESVVDHRR--------------VEDLLQFINSS 858
E EK ++ K +++ K D + E E + DHR +ED + +S
Sbjct: 25 EQEEKAEIKRLKNSDDRDSKRDSLEEGE-LRDHRMEITIRNSPYRREDSMEDRGEEDDSL 83
Query: 859 ETKPVSSTRAAKRARH-KQRKLEEKARLEAE-ARAREHLHLQEEQRRREEEEDEEEEEDR 916
KP ++ H K K +EK R + A +H ++E++R E + EE+D+
Sbjct: 84 AIKPPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEKEREHERRKRHREEQDK 143
Query: 917 FKEEFQR-----------------LQELQ-------KLRAVKKKKKERPSKDCPKLDMLT 952
+ E++R L++L+ K+R +K+++E+
Sbjct: 144 ARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKE---------- 193
Query: 953 RNFQAATESVPNSGNIHNGSLEQTEEPETSSHSPSRHMNHSEPRPGLGAD--GDAADPVD 1010
R +A + +T + S + H + S PRP GD PV
Sbjct: 194 RERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPV- 252
Query: 1011 TRDSKFLLPKEVNGKQHEPLSFFFDIMQHHKEGNGKQKLRQTSKASSEPARRPTEPPKAT 1070
KE ++ + LS DI R+TS A S A E +
Sbjct: 253 ---------KEEKMEERDLLSDLQDISDSE---------RKTSSAESSSA----ESGSGS 290
Query: 1071 EGQSKPRAQTESKAKVVDLMSITEQKREERKVNSNNNNKKQLNHIKDEKSNPTPMEPTSP 1130
E + + + E + + E++ EE + + +N+++ +E S E S
Sbjct: 291 EEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSE----EEMSE 346
Query: 1131 GEHQQNSK--LVLAES--PQPKGKNKKNKKKKGD 1160
E ++N LV+ ES + G++++ +++ G+
Sbjct: 347 DEERENENHLLVVPESRFDRDSGESEEAEEEVGE 380
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 55.1 bits (131), Expect = 4e-07
Identities = 81/386 (20%), Positives = 153/386 (39%), Gaps = 70/386 (18%)
Query: 813 EMREKLRLRLTKRKEEQPKKMDQISERESVVDH-----------RR---VEDLLQFINSS 858
E EK ++ K +++ K D + E E + DH RR +ED + +S
Sbjct: 25 EQEEKAEIKRLKNSDDRDSKRDSLEEGE-LRDHCMEITIRNSPYRREDSMEDRGEEDDSL 83
Query: 859 ETKPVSSTRAAKRARH-KQRKLEEKARLEAEARAREHLHLQEEQRRREEEEDEEEEEDRF 917
KP ++ H K K +EK R + + A H + ++R E + EE+D+
Sbjct: 84 AIKPPQQMSRKEKVHHRKDEKRKEKCRHHSHS-AEGGKHARVKEREHERRKRHREEQDKA 142
Query: 918 KEEFQ-----------------RLQELQKLRAVKKKKKERPSKDCPKLDMLTRNFQAATE 960
+ E++ RL++L++ R ++K +E+ + + + R +A
Sbjct: 143 RREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKE---QREQKERERRAEER 199
Query: 961 SVPNSGNIHNGSLEQTEEPETSSHSPSRHMNHSEPRPGLGAD--GDAADPVDTRDSKFLL 1018
+ +T + S + H + S PRP GD PV
Sbjct: 200 RKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPV--------- 250
Query: 1019 PKEVNGKQHEPLSFFFDIMQHHKEGNGKQKLRQTSKASSEPARRPTEPPKATEGQSKPRA 1078
KE ++ + LS DI R+TS A S A E +E + +
Sbjct: 251 -KEEKMEERDLLSDLQDISDSE---------RKTSSAESSSA----ESGSGSEEEEEEEE 296
Query: 1079 QTESKAKVVDLMSITEQKREERKVNSNNNNKKQLNHIKDEKSNPTPMEPTSPGEHQQNSK 1138
+ E + + E++ EE + + +N+++ +E S E S E ++N
Sbjct: 297 EEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSE----EEMSEDEERENEN 352
Query: 1139 --LVLAES--PQPKGKNKKNKKKKGD 1160
LV+ ES + G++++ +++ G+
Sbjct: 353 HLLVVPESRFDRDSGESEEAEEEVGE 378
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 54.3 bits (129), Expect = 7e-07
Identities = 69/320 (21%), Positives = 128/320 (40%), Gaps = 28/320 (8%)
Query: 813 EMREKLRLRLTKRKEEQPKKMDQISERESVVDHRRVEDLLQFINSSETKPVSSTRAAKRA 872
E RE+ R R +R+ E+ K+ ++ ER+ D + D + R R
Sbjct: 321 ERREREREREREREREKEKERERERERDRDRDRTKERD--------RDRDRERDRDRDRE 372
Query: 873 RHKQRKLEEKARLEAEARAREHLHLQEEQRRREEEEDEEEEEDRFKEEFQRLQELQKLRA 932
R R ++++R ++R RE +E +R RE E + E E +R +E +R +E +K +
Sbjct: 373 RSSDRN-KDRSRSREKSRDRERERERERERERERERERERERERERER-EREREREKDKK 430
Query: 933 VKKKKKERPSKDCPKLDMLTRNFQAATESVPNSGNIHNGSLEQTEEPETSSHSPSRHMNH 992
+++ E + + KL+ R +AA + + I + E E R
Sbjct: 431 RDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMA 490
Query: 993 SEPRPGL----GADGDAADPVDTRDSKFLLPKEVNGKQHEPLSFFFDIMQHHKEGNGKQK 1048
E + D D DP R S L K + ++ E + D +E ++
Sbjct: 491 KEAKRLKEFLEDYDDDRDDPKYYRGS--ALQKRLRDREKEMEA---DERDRKREKEELEE 545
Query: 1049 LRQTSKASSEPARRPTEPPKATEGQSKPRAQTESKAKVVDLMSITEQKREERKVNSNNNN 1108
+RQ A P P + E +++ R Q + K + E + EE +
Sbjct: 546 IRQRLLAEGHP--DPDAELQRMEQEAERRRQPQIKQE-------PESEEEEEEKQEKEEK 596
Query: 1109 KKQLNHIKDEKSNPTPMEPT 1128
+++ ++E ++PT
Sbjct: 597 REEPMEEEEEPEQKPCLKPT 616
Score = 45.1 bits (105), Expect = 4e-04
Identities = 70/353 (19%), Positives = 131/353 (37%), Gaps = 64/353 (18%)
Query: 811 YAEMREKLRLRLTKRKEEQPKKMDQISER--ESVVDHRRVEDLLQFINSSETKPVSSTRA 868
Y E + +R K+ E K+ ++ ER E + +R+++ L+ + P +
Sbjct: 457 YQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGS 516
Query: 869 A--KRARHKQRKLE------------------------------EKARLEAEARAREHLH 896
A KR R +++++E E R+E EA R
Sbjct: 517 ALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQ 576
Query: 897 LQEEQRRREEEEDEEEEEDRFKEEFQRLQELQKLRAVKKKKKERPSKDCPKLDMLTRNFQ 956
+++E EEEE+++E+E++ +E + +E ++ +K RP P + + N
Sbjct: 577 IKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKPCLKPTL--RPISSAPSVSSASGN-- 632
Query: 957 AATESVPNSGNIHNGSLEQTEEPETSSHSPSRHMNHSEPRPGLGADGDAADPVDTRDSKF 1016
AT + P + + P+ P H LGA P + K
Sbjct: 633 -ATPNTPGDESPCGIIIPHENSPD--QQQPEEHRPKIGLSLKLGASNSPGQPNSVKRKKL 689
Query: 1017 LLPKEVNGKQHEPLSFFFDIMQHHKEGNGKQKLRQTSKASSEPARRPTEPPKATEGQSK- 1075
P+ F+ + + +K + E + T+ TE + K
Sbjct: 690 ------------PVDSVFNKFEDEDSDDVPRKRKLVPLDYGEDDKNATKGTVNTEEKRKH 737
Query: 1076 --------PRAQTESKAKVVDLMSITEQKREERKVNSNNNNKKQLNHIKDEKS 1120
P A+ E A +D SI + ER++ NKK + +I +E++
Sbjct: 738 IKSLIEKIPTAKPELFAYPLD-WSIVDSILMERRIRP-WINKKIIEYIGEEEA 788
Score = 43.9 bits (102), Expect = 0.001
Identities = 36/125 (28%), Positives = 65/125 (52%), Gaps = 10/125 (8%)
Query: 808 SRNYAEMREKLRLRLTKRKEEQPKKMDQISERESVVDHRRVEDLLQFINSSETKPVSSTR 867
+++ + REK R R +R+ E+ ++ ++ ERE + R + + E
Sbjct: 378 NKDRSRSREKSRDRERERERERERERERERERERERERERERERER---EREKDKKRDRE 434
Query: 868 AAKRARHKQRKLEEKARLEAEARAREHL---HLQEEQRRREEEEDEEEEEDRFKE---EF 921
+ +++RKLE K R E EA +E L ++E ++ RE E++ E EE+R +E E
Sbjct: 435 EDEEDAYERRKLERKLR-EKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEA 493
Query: 922 QRLQE 926
+RL+E
Sbjct: 494 KRLKE 498
Score = 38.1 bits (87), Expect = 0.052
Identities = 30/129 (23%), Positives = 58/129 (44%), Gaps = 9/129 (6%)
Query: 815 REKLRLRLTKRKEEQPKKMDQISERESVVDHRRVEDLLQFINSSETKPVSSTRAAKRARH 874
RE + R T +K E+ K + ER+ + RR + E + R +R R
Sbjct: 279 REISKFRDTHKKLEEEKGKKE-KERQEIEKERRERE-----RERERERERRERERERERE 332
Query: 875 KQRKLEEKARLEAEA---RAREHLHLQEEQRRREEEEDEEEEEDRFKEEFQRLQELQKLR 931
++R+ E++ E E R R ++ R R+ + D E DR K+ + ++ +
Sbjct: 333 REREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRE 392
Query: 932 AVKKKKKER 940
+++++ER
Sbjct: 393 RERERERER 401
Score = 38.1 bits (87), Expect = 0.052
Identities = 24/75 (32%), Positives = 40/75 (53%), Gaps = 2/75 (2%)
Query: 870 KRARHKQRKLEEKARLEAEARAREHLHLQEEQRRREEEEDEEEEEDRFKEEFQRLQELQK 929
K K +K +E+ +E E R RE + E+ RRE E + E E +R KE+ +R +E ++
Sbjct: 290 KLEEEKGKKEKERQEIEKERRERER-ERERERERREREREREREREREKEK-ERERERER 347
Query: 930 LRAVKKKKKERPSKD 944
R + K+ +D
Sbjct: 348 DRDRDRTKERDRDRD 362
Score = 35.0 bits (79), Expect = 0.44
Identities = 22/90 (24%), Positives = 41/90 (45%)
Query: 855 INSSETKPVSSTRAAKRARHKQRKLEEKARLEAEARAREHLHLQEEQRRREEEEDEEEEE 914
I E K +R + R +KLEE+ + + R +E +R RE E + E E
Sbjct: 267 IEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERE 326
Query: 915 DRFKEEFQRLQELQKLRAVKKKKKERPSKD 944
+ E +R +E ++ R ++ + +K+
Sbjct: 327 REREREREREKEKERERERERDRDRDRTKE 356
Score = 35.0 bits (79), Expect = 0.44
Identities = 18/68 (26%), Positives = 34/68 (50%)
Query: 875 KQRKLEEKARLEAEARAREHLHLQEEQRRREEEEDEEEEEDRFKEEFQRLQELQKLRAVK 934
++R+ E + E E R RE +E +R +E+E + E E DR ++ + + +
Sbjct: 308 ERRERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDR 367
Query: 935 KKKKERPS 942
+ +ER S
Sbjct: 368 DRDRERSS 375
Score = 30.8 bits (68), Expect = 8.3
Identities = 27/129 (20%), Positives = 59/129 (45%), Gaps = 17/129 (13%)
Query: 828 EQPKKMDQISERESVVDHRRVEDLLQFINSSETKPVSSTRAAKRARHKQRKLEEKARLEA 887
+ + +D+ ++R + +E L++ +S P + + R + K++K + R
Sbjct: 191 DDEEALDEETKRRDQMIKGAIEVLIREYSSELNAPSQESDSHPRKKKKEKKEDIFRRFPV 250
Query: 888 EARAREHLHLQEEQRRREEEEDEEE----------------EEDRFKEEFQRLQELQKLR 931
L +E+ E EED+ + EE++ K+E +R QE++K R
Sbjct: 251 APLIPYPLITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKER-QEIEKER 309
Query: 932 AVKKKKKER 940
+++++ER
Sbjct: 310 RERERERER 318
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 53.9 bits (128), Expect = 9e-07
Identities = 83/382 (21%), Positives = 151/382 (39%), Gaps = 72/382 (18%)
Query: 813 EMREKLRLRLTKRKEEQPKKMDQISERESVVDH-----------RR---VEDLLQFINSS 858
E EK ++ K +++ K D + E E + DH RR +ED + +S
Sbjct: 25 EQEEKAEIKRLKNSDDRDSKRDSLEEGE-LRDHCMEITIRNSPYRREDSMEDRGEEDDSL 83
Query: 859 ETKPVSSTRAAKRARH-KQRKLEEK---ARLEAEARAREHLHLQEEQRRREEEEDEEEEE 914
KP ++ H K K +EK AR++ R H +E+ + R E E ++ E
Sbjct: 84 AIKPPQQMSRKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKARREWERQKRRE 143
Query: 915 ---DRFKEEFQRLQELQ-------KLRAVKKKKKERPSKDCPKLDMLTRNFQAATESVPN 964
+ + E RL++L+ K+R +K+++E+ R +A
Sbjct: 144 MAREHSRRERDRLEQLERKRERERKMREQQKEQREQKE----------RERRAEERRKER 193
Query: 965 SGNIHNGSLEQTEEPETSSHSPSRHMNHSEPRPGLGAD--GDAADPVDTRDSKFLLPKEV 1022
+ +T + S + H + S PRP GD PV KE
Sbjct: 194 EARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPV----------KEE 243
Query: 1023 NGKQHEPLSFFFDIMQHHKEGNGKQKLRQTSKASSEPARRPTEPPKATEGQSKPRAQTES 1082
++ + LS DI R+TS A S A E +E + + + E
Sbjct: 244 KMEERDLLSDLQDISDSE---------RKTSSAESSSA----ESGSGSEEEEEEEEEEEE 290
Query: 1083 KAKVVDLMSITEQKREERKVNSNNNNKKQLNHIKDEKSNPTPMEPTSPGEHQQNSK--LV 1140
+ + E++ EE + + +N+++ +E S E S E ++N LV
Sbjct: 291 EGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSE----EEMSEDEERENENHLLV 346
Query: 1141 LAES--PQPKGKNKKNKKKKGD 1160
+ ES + G++++ +++ G+
Sbjct: 347 VPESRFDRDSGESEEAEEEVGE 368
>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 53.9 bits (128), Expect = 9e-07
Identities = 107/446 (23%), Positives = 146/446 (32%), Gaps = 111/446 (24%)
Query: 367 GEPPGAPKEDGVLGSRSPRTEESKADSPPPSY---PTQQAEQAPNTCECHVCKQEASGLT 423
G PG P++ SP PPP P AP
Sbjct: 145 GPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAP---------------- 188
Query: 424 PSAMTAGALPPGHQFLSPEKPTHPALHLYPHIHGHVPLHTVPHLPRPLIHPTLYATPPFT 483
P AL P H SP PT P +P P PL A PP
Sbjct: 189 PPPPVLEALSPPHTLSSPSIPTPPDF--------------IPPAP-PL---AFLAPPPPP 230
Query: 484 HSKALPPAPVQNHTNKHQVFNASLQDHIYPSCFGNTPEWNSSKFISLWGSEVMNDKNWNP 543
PPAP HT ++F G +W S ++L G + + P
Sbjct: 231 VPAPAPPAPASPHTVGTRLFPP-----------GGVTKWKSD--VALNGRQAEATRASPP 277
Query: 544 GTFLPDTISGSEILGPT----LSETRPEALPPPSSNETPAVSDSKEKKNAAKKKCLYNFQ 599
+ P GS LGP L+ R +PPP+ T ++ Q
Sbjct: 278 RS--PAEPKGSA-LGPNPEPHLTFPRSFKVPPPTPVRTSSIP----------------VQ 318
Query: 600 DAFMEANKVVMATSSATSSVSCTATT-VQSSNSQFRVSSKRPPSVGDVFHGISKEDHRHS 658
+A K AT A S + + ++ ++ + + P G++ + +
Sbjct: 319 EAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGEL---------KAT 369
Query: 659 APAAPR------------NSPTGLAPLPALSPAALSPAALSPASTPHLANLAAPSFPKTA 706
APA+PR +P PLP +P PA P + P L P K A
Sbjct: 370 APASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPL-----PCAQKAA 424
Query: 707 TTTPGFVDTRKSFCPA----PLPPATDGSISAPPSVCSDP-DCEGHRCENGVYDPQQDDG 761
GF T KS PA P PP+ + + S+ P DP E R E Y
Sbjct: 425 HPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAY------L 478
Query: 762 DESADEDSCSEHSSSTSTSTNQKEGK 787
S ED H + + KEGK
Sbjct: 479 CGSRREDRFLSHRPGPTVAPQSKEGK 504
Score = 35.0 bits (79), Expect = 0.44
Identities = 117/536 (21%), Positives = 170/536 (31%), Gaps = 64/536 (11%)
Query: 241 PLQVDPAPDYLAERSPPSVSSASSGSGSSSPITIQQHPRLILTDSGSAPTFCSDDEDVAP 300
P P P L SPP + SS S + P I P L P A
Sbjct: 184 PSMAPPPPPVLEALSPPH--TLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPAS 241
Query: 301 LSAKFADIYPLSNYDDTEVVANMNGIHSELNGGGENMALKDESPQISSTSSSSSEADDEE 360
++P + +NG +E A SP S+ +
Sbjct: 242 PHTVGTRLFPPGGVTKWKSDVALNGRQAEAT-----RASPPRSPAEPKGSALGPNPEPHL 296
Query: 361 ADGESSGEPPGAPKEDGVL----GSRSPRTEES---KADSP---PPSYPTQQAEQA-PNT 409
S PP P + +PR EE KA S PPS+ + A Q P+
Sbjct: 297 TFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDR 356
Query: 410 CECHVCKQEASGLTPSAMT-----------AGALPPGHQFLSPEKPTHPALHLYPHIHGH 458
C E P++ AG PP P P P P
Sbjct: 357 APEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPP 416
Query: 459 VPLHTVPHLPRPLIHPTLYATPPFTHSKALPPAPVQNHTNKHQVFNASLQDHIYPSCFGN 518
+P P P + P + S AL P P N + +++ D PS
Sbjct: 417 LPCAQKAAHP-----PAGFTKTPKSSSPALKPKP--NPPSPENTASSAPVDWRDPS---Q 466
Query: 519 TPEWNSSKFISLWGSEVMNDK--NWNPG-TFLPDTISGSEILGPTLSETR-----PEALP 570
+ + L GS D+ + PG T P + G + GP L E P
Sbjct: 467 MEKLRNELAAYLCGSR-REDRFLSHRPGPTVAPQSKEGKK--GPRLPEKETLLSLPAKDT 523
Query: 571 PPSSNETPAVSDSKEKKNAAKKKCLYNFQDAFMEANKVVMATSSATSSVSCTATTVQSSN 630
PP E S + AA L + ++ + + + + ++
Sbjct: 524 PPGVPEKSLGGSSLTETEAAPSLTLPSVD--YIPQDSPTPSVRQIRNELEARLSSAAEKE 581
Query: 631 SQFRVSS--KRPPSVGDVFHGISKEDHRHSAPAAPRNSP--TGLAPLPALSPAALSPAAL 686
++ + S +P G +D + S P A P T L P +L P A+ A+
Sbjct: 582 AKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAI 641
Query: 687 SPASTPHLANLAAPSFPKTATTTPGFVDTRKSFCPAPLPPATDGSISAPPSVCSDP 742
P +TP P+ P AT P + + PA AT G + P S P
Sbjct: 642 PPKATPE------PAIPPKATLWPA-TPPKATLGPATPLKATSGP-TTPLKATSGP 689
>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 53.9 bits (128), Expect = 9e-07
Identities = 107/446 (23%), Positives = 146/446 (32%), Gaps = 111/446 (24%)
Query: 367 GEPPGAPKEDGVLGSRSPRTEESKADSPPPSY---PTQQAEQAPNTCECHVCKQEASGLT 423
G PG P++ SP PPP P AP
Sbjct: 145 GPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAP---------------- 188
Query: 424 PSAMTAGALPPGHQFLSPEKPTHPALHLYPHIHGHVPLHTVPHLPRPLIHPTLYATPPFT 483
P AL P H SP PT P +P P PL A PP
Sbjct: 189 PPPPVLEALSPPHTLSSPSIPTPPDF--------------IPPAP-PL---AFLAPPPPP 230
Query: 484 HSKALPPAPVQNHTNKHQVFNASLQDHIYPSCFGNTPEWNSSKFISLWGSEVMNDKNWNP 543
PPAP HT ++F G +W S ++L G + + P
Sbjct: 231 VPAPAPPAPASPHTVGTRLFPP-----------GGVTKWKSD--VALNGRQAEATRASPP 277
Query: 544 GTFLPDTISGSEILGPT----LSETRPEALPPPSSNETPAVSDSKEKKNAAKKKCLYNFQ 599
+ P GS LGP L+ R +PPP+ T ++ Q
Sbjct: 278 RS--PAEPKGSA-LGPNPEPHLTFPRSFKVPPPTPVRTSSIP----------------VQ 318
Query: 600 DAFMEANKVVMATSSATSSVSCTATT-VQSSNSQFRVSSKRPPSVGDVFHGISKEDHRHS 658
+A K AT A S + + ++ ++ + + P G++ + +
Sbjct: 319 EAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGEL---------KAT 369
Query: 659 APAAPR------------NSPTGLAPLPALSPAALSPAALSPASTPHLANLAAPSFPKTA 706
APA+PR +P PLP +P PA P + P L P K A
Sbjct: 370 APASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPL-----PCAQKAA 424
Query: 707 TTTPGFVDTRKSFCPA----PLPPATDGSISAPPSVCSDP-DCEGHRCENGVYDPQQDDG 761
GF T KS PA P PP+ + + S+ P DP E R E Y
Sbjct: 425 HPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAY------L 478
Query: 762 DESADEDSCSEHSSSTSTSTNQKEGK 787
S ED H + + KEGK
Sbjct: 479 CGSRREDRFLSHRPGPTVAPQSKEGK 504
Score = 35.0 bits (79), Expect = 0.44
Identities = 117/536 (21%), Positives = 170/536 (31%), Gaps = 64/536 (11%)
Query: 241 PLQVDPAPDYLAERSPPSVSSASSGSGSSSPITIQQHPRLILTDSGSAPTFCSDDEDVAP 300
P P P L SPP + SS S + P I P L P A
Sbjct: 184 PSMAPPPPPVLEALSPPH--TLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPAS 241
Query: 301 LSAKFADIYPLSNYDDTEVVANMNGIHSELNGGGENMALKDESPQISSTSSSSSEADDEE 360
++P + +NG +E A SP S+ +
Sbjct: 242 PHTVGTRLFPPGGVTKWKSDVALNGRQAEAT-----RASPPRSPAEPKGSALGPNPEPHL 296
Query: 361 ADGESSGEPPGAPKEDGVL----GSRSPRTEES---KADSP---PPSYPTQQAEQA-PNT 409
S PP P + +PR EE KA S PPS+ + A Q P+
Sbjct: 297 TFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDR 356
Query: 410 CECHVCKQEASGLTPSAMT-----------AGALPPGHQFLSPEKPTHPALHLYPHIHGH 458
C E P++ AG PP P P P P
Sbjct: 357 APEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPP 416
Query: 459 VPLHTVPHLPRPLIHPTLYATPPFTHSKALPPAPVQNHTNKHQVFNASLQDHIYPSCFGN 518
+P P P + P + S AL P P N + +++ D PS
Sbjct: 417 LPCAQKAAHP-----PAGFTKTPKSSSPALKPKP--NPPSPENTASSAPVDWRDPS---Q 466
Query: 519 TPEWNSSKFISLWGSEVMNDK--NWNPG-TFLPDTISGSEILGPTLSETR-----PEALP 570
+ + L GS D+ + PG T P + G + GP L E P
Sbjct: 467 MEKLRNELAAYLCGSR-REDRFLSHRPGPTVAPQSKEGKK--GPRLPEKETLLSLPAKDT 523
Query: 571 PPSSNETPAVSDSKEKKNAAKKKCLYNFQDAFMEANKVVMATSSATSSVSCTATTVQSSN 630
PP E S + AA L + ++ + + + + ++
Sbjct: 524 PPGVPEKSLGGSSLTETEAAPSLTLPSVD--YIPQDSPTPSVRQIRNELEARLSSAAEKE 581
Query: 631 SQFRVSS--KRPPSVGDVFHGISKEDHRHSAPAAPRNSP--TGLAPLPALSPAALSPAAL 686
++ + S +P G +D + S P A P T L P +L P A+ A+
Sbjct: 582 AKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAI 641
Query: 687 SPASTPHLANLAAPSFPKTATTTPGFVDTRKSFCPAPLPPATDGSISAPPSVCSDP 742
P +TP P+ P AT P + + PA AT G + P S P
Sbjct: 642 PPKATPE------PAIPPKATLWPA-TPPKATLGPATPLKATSGP-TTPLKATSGP 689
>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo
sapiens]
Length = 1188
Score = 53.9 bits (128), Expect = 9e-07
Identities = 107/446 (23%), Positives = 146/446 (32%), Gaps = 111/446 (24%)
Query: 367 GEPPGAPKEDGVLGSRSPRTEESKADSPPPSY---PTQQAEQAPNTCECHVCKQEASGLT 423
G PG P++ SP PPP P AP
Sbjct: 145 GPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAP---------------- 188
Query: 424 PSAMTAGALPPGHQFLSPEKPTHPALHLYPHIHGHVPLHTVPHLPRPLIHPTLYATPPFT 483
P AL P H SP PT P +P P PL A PP
Sbjct: 189 PPPPVLEALSPPHTLSSPSIPTPPDF--------------IPPAP-PL---AFLAPPPPP 230
Query: 484 HSKALPPAPVQNHTNKHQVFNASLQDHIYPSCFGNTPEWNSSKFISLWGSEVMNDKNWNP 543
PPAP HT ++F G +W S ++L G + + P
Sbjct: 231 VPAPAPPAPASPHTVGTRLFPP-----------GGVTKWKSD--VALNGRQAEATRASPP 277
Query: 544 GTFLPDTISGSEILGPT----LSETRPEALPPPSSNETPAVSDSKEKKNAAKKKCLYNFQ 599
+ P GS LGP L+ R +PPP+ T ++ Q
Sbjct: 278 RS--PAEPKGSA-LGPNPEPHLTFPRSFKVPPPTPVRTSSIP----------------VQ 318
Query: 600 DAFMEANKVVMATSSATSSVSCTATT-VQSSNSQFRVSSKRPPSVGDVFHGISKEDHRHS 658
+A K AT A S + + ++ ++ + + P G++ + +
Sbjct: 319 EAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGEL---------KAT 369
Query: 659 APAAPR------------NSPTGLAPLPALSPAALSPAALSPASTPHLANLAAPSFPKTA 706
APA+PR +P PLP +P PA P + P L P K A
Sbjct: 370 APASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPL-----PCAQKAA 424
Query: 707 TTTPGFVDTRKSFCPA----PLPPATDGSISAPPSVCSDP-DCEGHRCENGVYDPQQDDG 761
GF T KS PA P PP+ + + S+ P DP E R E Y
Sbjct: 425 HPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAY------L 478
Query: 762 DESADEDSCSEHSSSTSTSTNQKEGK 787
S ED H + + KEGK
Sbjct: 479 CGSRREDRFLSHRPGPTVAPQSKEGK 504
Score = 35.0 bits (79), Expect = 0.44
Identities = 117/536 (21%), Positives = 170/536 (31%), Gaps = 64/536 (11%)
Query: 241 PLQVDPAPDYLAERSPPSVSSASSGSGSSSPITIQQHPRLILTDSGSAPTFCSDDEDVAP 300
P P P L SPP + SS S + P I P L P A
Sbjct: 184 PSMAPPPPPVLEALSPPH--TLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPAS 241
Query: 301 LSAKFADIYPLSNYDDTEVVANMNGIHSELNGGGENMALKDESPQISSTSSSSSEADDEE 360
++P + +NG +E A SP S+ +
Sbjct: 242 PHTVGTRLFPPGGVTKWKSDVALNGRQAEAT-----RASPPRSPAEPKGSALGPNPEPHL 296
Query: 361 ADGESSGEPPGAPKEDGVL----GSRSPRTEES---KADSP---PPSYPTQQAEQA-PNT 409
S PP P + +PR EE KA S PPS+ + A Q P+
Sbjct: 297 TFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDR 356
Query: 410 CECHVCKQEASGLTPSAMT-----------AGALPPGHQFLSPEKPTHPALHLYPHIHGH 458
C E P++ AG PP P P P P
Sbjct: 357 APEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPP 416
Query: 459 VPLHTVPHLPRPLIHPTLYATPPFTHSKALPPAPVQNHTNKHQVFNASLQDHIYPSCFGN 518
+P P P + P + S AL P P N + +++ D PS
Sbjct: 417 LPCAQKAAHP-----PAGFTKTPKSSSPALKPKP--NPPSPENTASSAPVDWRDPS---Q 466
Query: 519 TPEWNSSKFISLWGSEVMNDK--NWNPG-TFLPDTISGSEILGPTLSETR-----PEALP 570
+ + L GS D+ + PG T P + G + GP L E P
Sbjct: 467 MEKLRNELAAYLCGSR-REDRFLSHRPGPTVAPQSKEGKK--GPRLPEKETLLSLPAKDT 523
Query: 571 PPSSNETPAVSDSKEKKNAAKKKCLYNFQDAFMEANKVVMATSSATSSVSCTATTVQSSN 630
PP E S + AA L + ++ + + + + ++
Sbjct: 524 PPGVPEKSLGGSSLTETEAAPSLTLPSVD--YIPQDSPTPSVRQIRNELEARLSSAAEKE 581
Query: 631 SQFRVSS--KRPPSVGDVFHGISKEDHRHSAPAAPRNSP--TGLAPLPALSPAALSPAAL 686
++ + S +P G +D + S P A P T L P +L P A+ A+
Sbjct: 582 AKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAI 641
Query: 687 SPASTPHLANLAAPSFPKTATTTPGFVDTRKSFCPAPLPPATDGSISAPPSVCSDP 742
P +TP P+ P AT P + + PA AT G + P S P
Sbjct: 642 PPKATPE------PAIPPKATLWPA-TPPKATLGPATPLKATSGP-TTPLKATSGP 689
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 53.9 bits (128), Expect = 9e-07
Identities = 97/481 (20%), Positives = 190/481 (39%), Gaps = 90/481 (18%)
Query: 772 EHSSSTSTSTNQKEGKYCDCCYC-EFFGHGG---------PPAAPTSR------------ 809
E + S ++++ +Y C Y + F HG PP PT +
Sbjct: 251 EDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPAIPPPLPTEQASRPTPASPALE 310
Query: 810 ---NYAEMREKLRLRLTKRKEEQPKKMDQISERESVVDHRRVEDLLQFINSSETKPVSST 866
+ EK TK+KE++ K SE+E+ +D + E +SETK +
Sbjct: 311 EKEGEKKKAEKKVTSETKKKEKEDIKKK--SEKETAIDVEKKEP----GKASETKQGTVK 364
Query: 867 RAAKRARHKQRKLEEKARLEAEARAREHLHLQEEQRRREEE-------EDEEEEEDRFKE 919
AA+ A K K E+ + + A + ++E++ + E E + + K
Sbjct: 365 IAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKA 424
Query: 920 EFQRLQE----LQKLRAVKKKKKERPSKDCPKLDMLTRNFQAATESVPNSGNIHNGSLEQ 975
+ +R +E + +AV KK+E+ +K + + + T S+ G E+
Sbjct: 425 KTERAKEEIGAVSIKKAVPGKKEEKTTKTVEQ--EIRKEKSGKTSSILKDKEPIKGKEEK 482
Query: 976 T------EEPET-SSHSPSRHMNHSEPRPG--LGADGDAADPVDTRDSKFLLPKEVNGKQ 1026
+EPET S+ +P+P G + +P +++K + ++V +
Sbjct: 483 VPASLKEKEPETKKDEKMSKAGKEVKPKPPQLQGKKEEKPEPQIKKEAKPAISEKVQIHK 542
Query: 1027 HEPLSFFFDIMQHHK---EGNGKQK-LRQTSKASSEPARRPTEPPKATEGQSKPRAQTES 1082
DI++ K G ++K L+Q + E +P KA + +P +
Sbjct: 543 Q-------DIVKPEKTVSHGKPEEKVLKQVKAVTIEKTAKPKPTKKAEHREREPPSIKTD 595
Query: 1083 KAKVV--DLMSITEQKREERKVNSNNNNKK-QLNHIKDEKSNPTPMEPTSPGEHQQNSKL 1139
K K +TE +++ +++ + +K + H+++EK ++ E Q +
Sbjct: 596 KPKPTPKGTSEVTESGKKKTEISEKESKEKADMKHLREEK-------VSTRKESLQLHNV 648
Query: 1140 VLAESPQPKGKNKKNKKKKGDRVNNSIDDVFLPKDIDLDSVDMDETERE--VEYFKRFCL 1197
AE P RV+ ++DV K + D+ T+++ + +F+ L
Sbjct: 649 TKAEKPA--------------RVSKDVEDVPASKKAKEGTEDVSPTKQKSPISFFQCVYL 694
Query: 1198 D 1198
D
Sbjct: 695 D 695
Score = 48.9 bits (115), Expect = 3e-05
Identities = 74/329 (22%), Positives = 124/329 (37%), Gaps = 57/329 (17%)
Query: 905 EEEEDEEEEEDRFKEEFQ----RLQELQKLRAVKKKKKERPSKDCPKLDMLTRNFQAATE 960
E+EED++ +ED K E R +E+ K + K++K ER + + + E
Sbjct: 117 EDEEDDDGDEDTDKGEIDEPPLRKKEIHKDKTEKQEKPERKIQTKVTHKEKEKGKEKVRE 176
Query: 961 -SVPNSGNIHNGSLEQTEEPETSS----HSPSRHMNHSEPRPGLGADGDAADPVDTRDSK 1015
P H +E+ E+PET + ++ SE + G + V +K
Sbjct: 177 KEKPEKKATHKEKIEKKEKPETKTLAKEQKKAKTAEKSEEKTKKEVKGGKQEKVKQTAAK 236
Query: 1016 F-------LLPKEVNGKQHEPLS------------FFFDIMQHHKEGNGKQKLRQTSKAS 1056
PKE K+ +S + DI H G Q
Sbjct: 237 VKEVQKTPSKPKEKEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPG-QSPAIPPPLP 295
Query: 1057 SEPARRPTEPPKATEGQSKPRAQTESKAKVVDLMSITEQKREERKVNSNNNNKKQLNHIK 1116
+E A RPT A E + + + E K +T + +++ K + ++K+ I
Sbjct: 296 TEQASRPTPASPALEEKEGEKKKAEKK--------VTSETKKKEKEDIKKKSEKE-TAID 346
Query: 1117 DEKSNPTPMEPTSPG-------------EHQQNSKLVL--AESPQPKGKNKKNKKKKGDR 1161
EK P T G E +++SK AE QPKGK ++ K+K +
Sbjct: 347 VEKKEPGKASETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKHVEP 406
Query: 1162 VNNSIDDVFLPKDIDLDSVDMDETEREVE 1190
+ + +P D + + +TER E
Sbjct: 407 AKSPKKEHSVPSDKQVKA----KTERAKE 431
Score = 45.8 bits (107), Expect = 2e-04
Identities = 74/358 (20%), Positives = 138/358 (38%), Gaps = 73/358 (20%)
Query: 826 KEEQPKKMDQISERESVVDHRRVEDLLQFINSSETKPVSSTRAAKRARHKQRKLEEKARL 885
K+E+P++ Q V H+ E + + E + K+A HK+ K+E+K +
Sbjct: 150 KQEKPERKIQTK-----VTHKEKEKGKEKVREKE-------KPEKKATHKE-KIEKKEKP 196
Query: 886 EAEARAREHLHLQEEQRRREEEEDEEE--EEDRFKEEFQRLQELQKLRAVKKKKKERPSK 943
E + A+E + ++ E+ + E + ++++ K+ +++E+QK K KE+ K
Sbjct: 197 ETKTLAKEQKKAKTAEKSEEKTKKEVKGGKQEKVKQTAAKVKEVQK---TPSKPKEKEDK 253
Query: 944 DCPKLDMLTRNFQAATESVPNSGNIHNGSLEQTEEPETSSHSPSRHMNHSEPRPGLGADG 1003
+ + + Q A +H G L+ + P P+ S P P
Sbjct: 254 EKAAVSKHEQKDQYAFCRYMIDIFVH-GDLKPGQSPAIPPPLPTEQA--SRPTPA----- 305
Query: 1004 DAADPVDTRDSKFLLPKEVNGKQHEPLSFFFDIMQHHKEGNGKQKLRQTSKASSEPARRP 1063
S L KE K+ E K+ +T K E ++
Sbjct: 306 ----------SPALEEKEGEKKKAE-----------------KKVTSETKKKEKEDIKKK 338
Query: 1064 TEPPKATEGQSK-PRAQTESKAKVVDLMSITEQKREERKVNSNNNNKKQLNHIKDEKSNP 1122
+E A + + K P +E+K V + + K++E+K +D K
Sbjct: 339 SEKETAIDVEKKEPGKASETKQGTVKIAAQAAAKKDEKK--------------EDSKKTK 384
Query: 1123 TPMEPTSP-GEHQQNSKLVLAESPQPKGKNK----KNKKKKGDRVNNSIDDVFLPKDI 1175
P E P G+ Q+ + + + PK ++ K K K +R I V + K +
Sbjct: 385 KPAEVEQPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKKAV 442
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 53.9 bits (128), Expect = 9e-07
Identities = 80/359 (22%), Positives = 134/359 (37%), Gaps = 39/359 (10%)
Query: 800 GGPPAAPTSRNYAEMREKLRLRLTKRKEEQPKKMDQISERESVVDHRRVEDLLQFINSSE 859
G PA + AE+ EK RL D + S RR + Q
Sbjct: 113 GQRPAVTETHQLAELNEKKNERLRAAFGIS----DSYVDGSSFDPQRRAREAKQPA-PEP 167
Query: 860 TKPVSSTRAAKRARHKQRKLEEKARLEAEARAREHLHLQEEQRRREEEEDEEEEEDRFKE 919
KP S R + +R K ++K + + R E + E+++ +++ E + K
Sbjct: 168 PKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKR 227
Query: 920 EFQRLQELQKLRAV-KKKKKERPSKDCPKLDMLTRNFQAATESVPNSGNIHNGSLE-QTE 977
+ + K ++ KK+K+ R + PK R+ A + S ++ + S +T
Sbjct: 228 KHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTH 287
Query: 978 EPETSSHSPSRHMNHSEPRPGLGADGDA--ADPVDTRDSKFLLPKEVNGKQHEPLSFFFD 1035
+ SPS P G +GDA ++P T + P +P S + D
Sbjct: 288 TTALAGRSPS-------PASGRRGEGDAPFSEPGTTSTQR---PSSPETATKQPSSPYED 337
Query: 1036 IMQHHKEGNGKQKLRQTSKASSEPARRPTEPPKATE-------GQSKPRAQTESKAKVVD 1088
K+ + K+K S E + EPP T G +P A T + V+
Sbjct: 338 -----KDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVN 392
Query: 1089 LMSITEQKREERKVNSNNNNKKQLNHIKDEKSNPTPMEPTSPGEHQQNSKLVLAESPQP 1147
S R+ S + ++L +S+P +PT H +S ESP+P
Sbjct: 393 PPSEASPTRD----RSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSS----PESPKP 443
Score = 41.2 bits (95), Expect = 0.006
Identities = 144/697 (20%), Positives = 244/697 (35%), Gaps = 87/697 (12%)
Query: 257 PSVSSASSGSGSSSPITIQQHPRLILTDSGSAPTFCSDDEDVA--PLSA-------KFAD 307
P+VS S S + + + P + S P F + ++++ PL +F +
Sbjct: 1278 PAVSLTLDQSQSQASLEAVEVPSM--ASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRN 1335
Query: 308 IYPLSNYDDT----EVVANMNGIHSELNGGGENMALKDESPQISSTSSSSSEADDEEADG 363
PL +T EV ++NG ++ +K++S + S SSS D E G
Sbjct: 1336 SGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAG 1395
Query: 364 ESSGEPPGAPKEDGVLGSRSPRTEESKADSPPPSYPTQQAEQAPNTCECHVCKQEASGLT 423
SS + +P D V R+P E S + S P + + P T ++ SG +
Sbjct: 1396 MSSNQSISSPVLDAV--PRTPSRERSSSASSP-----EMKDGLPRTPS----RRSRSGSS 1444
Query: 424 PSAMTAGALPPGHQFLSPEKPTHPALHLYP-----HIHGHVPLHTVPHLPRPLIHPTLYA 478
P P H LS P + P +P PRP
Sbjct: 1445 PGLRDGSGTPSRHS-LSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSP--- 1500
Query: 479 TPPFTHSKALPPAPVQNHTNKHQVFNASLQDHIYPSCFGNTPEWNSSKFISLWGSEVMND 538
+ P ++K L P ++ + ++ Q + + G SS+ + + S +
Sbjct: 1501 SSPELNNKCLTPQRERSGSE-----SSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQE 1555
Query: 539 KNWNPGTFLPDTISGSEILGPTLSETRPEALPP--------PSSNETPAVSDSKEKKNAA 590
++ + + PD S ++ P +R + P P + + + + K+K AA
Sbjct: 1556 RSESDSS--PD--SKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAA 1611
Query: 591 KKKCLYNFQDAFME----ANKVVMATSSATSSVSCTATTVQSSNSQFRVSSKRPPSVGDV 646
+ + D+ E A + + S + SS + + S+S S + PP
Sbjct: 1612 PRA--QSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSST-ESSPEHPPKSRTA 1668
Query: 647 FHGI-SKEDHRHSAPAAPRNSPTGLAPLPALSPAALSPAALSPASTPHLANLAAP----- 700
G S + + + PR + +P A LS + S +S+P + P
Sbjct: 1669 RRGSRSSPEPKTKSRTPPRRRSSRSSP-ELTRKARLSRRSRSASSSPETRSRTPPRHRRS 1727
Query: 701 ---SFPKTATTTPGFVDTRKSFCPAPLPPATDGSISAPPSVCSDPDCEGHRCENGVYDPQ 757
S P+ A + R + P + G +P R E +
Sbjct: 1728 PSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRR 1787
Query: 758 QDDGDESADEDSCSEHSSSTSTSTNQKEGKYCDCCYCEFFGHGGPPAAPTSRNYAEMREK 817
+D S + S S S T ++ G Y H PA S + R +
Sbjct: 1788 RDRSGSSQSTSRRRQRSRSRSRVTRRRRG---GSGY-----HSRSPARQESSRTSSRRRR 1839
Query: 818 LRLRL--TKRKEEQ----PKKMDQISERESVVDHRRVEDLLQFI----NSSETKPVSSTR 867
R R T RK + P + R S HRR I + S T PVS R
Sbjct: 1840 GRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRR 1899
Query: 868 AAKRARHKQRKLEEKARLEAEARAREHLHLQEEQRRR 904
+ R +R+ +A + R+R +R R
Sbjct: 1900 SRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSR 1936
Score = 39.7 bits (91), Expect = 0.018
Identities = 34/142 (23%), Positives = 62/142 (43%), Gaps = 19/142 (13%)
Query: 1021 EVNGKQHEPLSFFFDIMQHHKEGNGKQKLRQTSKASSEPARRPTEPPKATEGQSKPRAQT 1080
E+N K++E L F I + +G+ R+ +A +PA P +P S R+ T
Sbjct: 126 ELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAK-QPAPEPPKPYSLVRESSSSRSPT 184
Query: 1081 ESKAKVVDLMSITEQKREERKVNSNNNNKKQLNHIKDEKSNPTPMEPTSPGEHQQNSKLV 1140
+ K ++K+++R S +++ ++ +K + +H+
Sbjct: 185 PKQKK--------KKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHR------ 230
Query: 1141 LAESPQPKGKNK-KNKKKKGDR 1161
SP PK K K K+KK+K R
Sbjct: 231 ---SPTPKSKRKSKDKKRKRSR 249
Score = 38.1 bits (87), Expect = 0.052
Identities = 116/632 (18%), Positives = 202/632 (31%), Gaps = 51/632 (8%)
Query: 562 SETRPEALPPPSSNETPAVSDSKEKKNA----AKKKCLYNFQDAFMEANKVVMATSSATS 617
S+ R P P S D K K++ A K + + A+ + S + S
Sbjct: 224 SKKRKHRSPTPKSKRKS--KDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRS 281
Query: 618 SVSCTATTVQSSNSQFRVSSKRPPSVGDVFHGISKEDHRHSAPAAPRNSPTG-------- 669
+ + T TT + S S +R + R S+P P+
Sbjct: 282 AAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKD 341
Query: 670 ----LAPLPALSPAALSPAALSPASTPHLANLAAPSFPKTATT--------TPGFVDTRK 717
A P+ SP S PA TP LA S ATT P +
Sbjct: 342 KKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTR 401
Query: 718 SFCPAPLP---PATDGSISAPPSVCSDPDCEGHRCENGVYDPQQDDGDESADEDSCSEHS 774
P P P + S S+PPS P + P+ S E S S S
Sbjct: 402 DRSPPKSPEKLPQSSSSESSPPS--PQPTKVSRHASSSPESPKPAPAPGSHREISSSPTS 459
Query: 775 SSTSTSTNQKEGKYCDCCYCEFFGHGGPPAAPTSRNYAEMREKLRLRLTKRKEEQPKKMD 834
+ S +++ + P A R+ + K ++ + + +
Sbjct: 460 KNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSA 519
Query: 835 QISERESVVDHR---RVEDLLQFINSSETKPVSSTRAAKRARHKQRKLEEKARLEAEARA 891
Q R R R + S T+ +R+A+R R R + R + A
Sbjct: 520 QRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPA 579
Query: 892 RE-HLHLQEEQRRREEEEDEEEEEDRFKEEFQRLQELQKLRAVKKKKKERPSKDCPKLDM 950
R + RRR R + +R + + A ++ + P + +
Sbjct: 580 RRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRS 639
Query: 951 LTRNFQAATESVPNSGNIHNGSLEQTEEPETSSHSPSRHMNHSEPR-PGLGADGDAADPV 1009
R + P + + S + S +P+R S R P + P
Sbjct: 640 PARRSGRSRSRTP-ARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPR 698
Query: 1010 DTRDSKFLLPKEVNGKQHEPLSFFFDIMQHHKEGNGKQKLRQTSKASSEPARRPTEPPKA 1069
R L + P ++ + R++ SS ++ +
Sbjct: 699 RGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRR 758
Query: 1070 TEGQSKPRAQTESKAKVVDLMS----ITEQKRE--ERKVNSNNNNKKQLNHIKDEK---- 1119
+ S PR++ +S+ + +S +QK + R+ S ++ K + +
Sbjct: 759 SRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSS 818
Query: 1120 SNPTPMEPTSPGEHQQNSKLVLAESPQPKGKN 1151
S+P P + + Q +S + SP PK K+
Sbjct: 819 SSPPPKQKSKTPSRQSHS----SSSPHPKVKS 846
Score = 35.0 bits (79), Expect = 0.44
Identities = 49/200 (24%), Positives = 73/200 (36%), Gaps = 24/200 (12%)
Query: 228 DPPVTDDIHIHQLPLQVDPAPDYLAERSPPSVSSASSGSGSSSPITIQQHPRLILTDSGS 287
+PP + + PA + + S S SS+SS S SSS + ++ S
Sbjct: 2508 EPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSS 2567
Query: 288 APTFCSDDEDVA------PLSAKFADIYPLSNYDDTEVVANMNGIHSELNGGGENMALKD 341
P +VA P A + + T S + + +
Sbjct: 2568 LPV----QPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSS 2623
Query: 342 ESPQISSTSSSSSEADDEEADGESSGEP----------PGAPKE--DGVLGSRSPRTE-E 388
S SS+SSSSS + + SS P P +PK+ G SRSPR +
Sbjct: 2624 SSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPID 2683
Query: 389 SKADSPPPSY-PTQQAEQAP 407
S DS SY P ++ +P
Sbjct: 2684 SLRDSRSLSYSPVERRRPSP 2703
Score = 34.7 bits (78), Expect = 0.57
Identities = 59/288 (20%), Positives = 113/288 (39%), Gaps = 20/288 (6%)
Query: 856 NSSETKPVSSTRAAKRARHKQRKLEEKARLEAEARAREHLHLQEEQRRREEE----EDEE 911
N + +S R + R + EE RLEA R + + + +R+R E E EE
Sbjct: 16 NGYVQRNLSLVRGRRGERPDYKGEEELRRLEAALVKRPNPDILDHERKRRVELRCLELEE 75
Query: 912 EEEDRFKEEFQRLQELQKLRAVKKKKKERP--SKDCP-KLDMLTRNFQAATESVPNSGNI 968
E++ EE Q +++ R + +K P ++ P + +T Q A + + +
Sbjct: 76 MMEEQGYEEQQIQEKVATFRLMLLEKDVNPGGKEETPGQRPAVTETHQLAELNEKKNERL 135
Query: 969 HNGSLEQTEEPETSSHSPSRHMNHSE------PRPGLGADGDAADPVDTRDSKFLLPKEV 1022
+ SS P R ++ P+P ++ T K K+
Sbjct: 136 RAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKD 195
Query: 1023 NGKQHEPLSFFFDIMQHHKEGNGKQKLRQTSKASSEPARRPTEPPKATEGQSKPRAQTES 1082
G++ E S + K+ + K+K R S++ R PT PK ++ +SK + + S
Sbjct: 196 RGRRSESSS----PRRERKKSSKKKKHRSESESKKRKHRSPT--PK-SKRKSKDKKRKRS 248
Query: 1083 KAKVVDLMSITEQKREERKVNSNNNNKKQLNHIKDEKSNPTPMEPTSP 1130
++ S + S+++ + + K++ T + SP
Sbjct: 249 RSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSP 296
Score = 33.1 bits (74), Expect = 1.7
Identities = 31/147 (21%), Positives = 58/147 (39%), Gaps = 9/147 (6%)
Query: 937 KKERPSKDCPKLDMLTRNFQAATESVPNSGNIHNGSLEQTEEPETSSHSPS--------R 988
K++R S + + +++ S +S + + S + +SS SP+ +
Sbjct: 2602 KRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPK 2661
Query: 989 HMNHSEPRPGLGADGDAADPVDT-RDSKFLLPKEVNGKQHEPLSFFFDIMQHHKEGNGKQ 1047
+ +P PG P+D+ RDS+ L V ++ P D E ++
Sbjct: 2662 PASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRR 2721
Query: 1048 KLRQTSKASSEPARRPTEPPKATEGQS 1074
R S++ S RR T P+ +S
Sbjct: 2722 GQRGDSRSPSHKRRRETPSPRPMRHRS 2748
Score = 32.7 bits (73), Expect = 2.2
Identities = 105/611 (17%), Positives = 184/611 (30%), Gaps = 89/611 (14%)
Query: 624 TTVQSSNSQFRVSSKRPPSVGDVFHGISKEDHRHSAPAAPRNSPTGL---APLPALS--- 677
TT S ++K+P S + KE +P S TG AP P L+
Sbjct: 315 TTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERH 374
Query: 678 -----PAALSPAALSPASTPHLANLAAPSFPKTATTTPGFVDTRKSFCPAPLPPATDGSI 732
P A +P + P + P A+ P + + +S P+P P
Sbjct: 375 GGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHA 434
Query: 733 SAPPSVCSDPDCEGHRCENGVYDPQQDDGDESADEDSCSEHSSS---------------- 776
S+ P G E ++ A D H+ S
Sbjct: 435 SSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGR 494
Query: 777 TSTSTNQKEG----------------KYCDCCYCEFFGHGGPPAAPTSRNYAEMREKLRL 820
+ + T K G ++ + G P P + + R
Sbjct: 495 SRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRS 554
Query: 821 RLTKRKEEQPKKMDQISERESVVDHRRVEDLLQFINSSETKPVSSTRAAKRARHKQRKLE 880
R +R + S RR + ++ + TR R+R R+
Sbjct: 555 RSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGR 614
Query: 881 EKARLEAEARAREHLHLQEEQRRREEEEDEEEEEDRFKEEFQRLQELQKLRAVK------ 934
++R A R+R ++ R R R R + R +
Sbjct: 615 SRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTP 674
Query: 935 -----KKKKERPSKDCPKLDMLTRNFQAATESVPNSGNIHNGSLEQ-------TEEPETS 982
+ + P++ R ++ + S+ G H+ + ++ +E S
Sbjct: 675 ARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKS 734
Query: 983 SHSPSRHMNHSEP-----RPGLGADGDAADPVDTRDSKFLLPKEVNGKQHEPLSFFFDIM 1037
S R ++S P R + P S+ L + ++G P
Sbjct: 735 RTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPP 794
Query: 1038 QHHKEGNGKQKL-------RQTSKASSEPARRPTEPPKATEGQSKPRAQTES-------- 1082
+ + G+ + K R S +S P ++ P + + S P + +S
Sbjct: 795 RRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGS 854
Query: 1083 -KAKVVDLMSITEQKRE--ERKVNSNNNNKKQLNHIKDEKSNPTPMEPTSPGEHQQNSKL 1139
+ + S+T Q+R E + ++ H S P T P + S
Sbjct: 855 ITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRS-- 912
Query: 1140 VLAESPQPKGK 1150
SPQPK K
Sbjct: 913 ---SSPQPKVK 920
Score = 31.2 bits (69), Expect = 6.3
Identities = 34/141 (24%), Positives = 50/141 (35%), Gaps = 26/141 (18%)
Query: 329 ELNGGGENMALKDESPQISSTSSSSSEADDEEADGESSG-------------EPPGAPKE 375
E + + S SS+SSSSS + +D E S P APKE
Sbjct: 2529 ERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKE 2588
Query: 376 DGVLGSRSP--------RTEESKADSPPPSYPTQQAEQAPNTCECHVCKQEASGLTPSAM 427
V R P R S + S S + + + ++ +S + S+
Sbjct: 2589 -AVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2647
Query: 428 TAGALPPGHQFL----SPEKP 444
+ PG Q L SP+KP
Sbjct: 2648 SPSPAKPGPQALPKPASPKKP 2668
Score = 30.8 bits (68), Expect = 8.3
Identities = 88/431 (20%), Positives = 159/431 (36%), Gaps = 69/431 (16%)
Query: 338 ALKDESPQISSTSSSSSEADDEE----ADGESSGEPPGAPKEDGVLGSRSPRTEESKADS 393
A+ SP+ + S+ + AD A + P A + GS +P T A +
Sbjct: 2267 AMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPT----AAN 2322
Query: 394 PPPSYPTQQAEQAPN---------TCECHVC-KQEASGLTPSAMTAGALPP---GHQFLS 440
P S T QA + N T ++ + A+ L P+++T+ + P G S
Sbjct: 2323 YPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTS 2382
Query: 441 PEKPTHPALHLYPHIHGHVPLHTVPHLPRPLIHPTLYATPP-------FTHSKALPPAPV 493
P P L Y + G T P PL+ TPP T +A P+
Sbjct: 2383 PRVP----LSAYERVSGR----TSP----PLLDRARSRTPPSAPSQSRMTSERAPSPSSR 2430
Query: 494 QNHTNKHQVFNASLQDHI---YPSCFGNTPEWNSSKFISLWGSEVMNDKNWNPGTFLPDT 550
+ + QD PS F + S+ + + V ++ + G T
Sbjct: 2431 MGQAPSQSLLPPA-QDQPRSPVPSAFSD-----QSRCLIAQTTPVAGSQSLSSGAVATTT 2484
Query: 551 ISGSEILG----PTLSETRPEALPPPSS------NETPAVSDSKEKKNAAKKKCLYNFQD 600
S + G P + PP+S + A+ +KE+++++ +
Sbjct: 2485 SSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSS 2544
Query: 601 AFMEANKVVMATSSATSSVSCTATTVQSSNSQFRVSSKRPPSVGDVFHGISKED-----H 655
+ ++ ++ S++S ++ VQ + RV S P V G E
Sbjct: 2545 SSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRK 2604
Query: 656 RHSAPAAPRNSPTGLAPLPALSPAALSPAALSPASTPHLANLAAPSFPKTATTTPGFVDT 715
R S+ ++ +S + + + S ++ S ++ S +S+ ++ ++PS K PG
Sbjct: 2605 RRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAK-----PGPQAL 2659
Query: 716 RKSFCPAPLPP 726
K P PP
Sbjct: 2660 PKPASPKKPPP 2670
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 53.5 bits (127), Expect = 1e-06
Identities = 35/139 (25%), Positives = 74/139 (53%), Gaps = 4/139 (2%)
Query: 809 RNYAEMREKLRLRLTKRKEEQP---KKMDQISERESVVDHRRVEDLLQFINSSETKPVSS 865
R ++ E+ ++R ++++EQ ++ ++I E+E + + + I E K
Sbjct: 441 RQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQ 500
Query: 866 TRAAKRARHKQRKLEEKA-RLEAEARAREHLHLQEEQRRREEEEDEEEEEDRFKEEFQRL 924
K R+ EEK R E + R +E ++E++ RE+EE +E+E++ E+ +++
Sbjct: 501 EEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKM 560
Query: 925 QELQKLRAVKKKKKERPSK 943
QE +K+R ++K +E+ K
Sbjct: 561 QEQEKMRRQEEKIREQEEK 579
Score = 48.9 bits (115), Expect = 3e-05
Identities = 55/298 (18%), Positives = 134/298 (44%), Gaps = 26/298 (8%)
Query: 813 EMREKLRLR---LTKRKEEQPKKMDQISERESVVDHRRVEDLL----QFINSSETKPVSS 865
E EK+R + + +++E+ ++ + + E+E + RR+E+++ + I E K
Sbjct: 332 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM--RRLEEMMWEKEEKIRELEEKMHEQ 389
Query: 866 TRAAKRARHKQRKLEEKARLEAEARAREHLHLQEEQRRREEEEDEEEEEDRFKEEFQRLQ 925
+ R + ++R+ EEK R + + + +E ++E++ RE+EE E+E + + +++
Sbjct: 390 EKI--REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIH 447
Query: 926 ELQKLRAVKKKKKERPSKDCPKLDMLTRNFQAATESVPNSGNIHNGSLEQTEEPETSSHS 985
E +K+R +K++++ ++ + E +H + +E +
Sbjct: 448 EQEKIREEEKRQEQE------EMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQE 501
Query: 986 PSRHMNHSEPRPGLGADGDAADPVDTRDSKFLLPKEVNGKQHEPLSFFFDIMQHHKEGNG 1045
H + R + + + ++ K +E +Q E + ++MQ +E G
Sbjct: 502 EKMHDQEEKIR-------EQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMG 554
Query: 1046 KQ--KLRQTSKASSEPARRPTEPPKATEGQSKPRAQTESKAKVVDLMSITEQKREERK 1101
+Q K+++ K + + + K E + K R Q E + + + E+ +E++
Sbjct: 555 EQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQE 612
Score = 43.9 bits (102), Expect = 0.001
Identities = 35/139 (25%), Positives = 73/139 (52%), Gaps = 10/139 (7%)
Query: 813 EMREKLRLRLTK--RKEEQPKKMDQ-ISERESVVDHRRVEDLLQFINSS---ETKPVSST 866
+ EK+R + K R+EE+ ++ ++ I E+E + R E+++Q + + +
Sbjct: 506 DQEEKIREQEEKMWRQEEKIREQEEKIREQEEKI--REQEEMMQEQEEKMGEQEEKMQEQ 563
Query: 867 RAAKRARHKQRKLEEKARLEAE--ARAREHLHLQEEQRRREEEEDEEEEEDRFKEEFQRL 924
+R K R+ EEK R + E E + QEE+ R +EE +E+EE +++E +
Sbjct: 564 EKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMC 623
Query: 925 QELQKLRAVKKKKKERPSK 943
++ +K++ ++K + + K
Sbjct: 624 EQEEKMQEQEEKMRRQEEK 642
Score = 43.1 bits (100), Expect = 0.002
Identities = 31/137 (22%), Positives = 69/137 (50%), Gaps = 6/137 (4%)
Query: 815 REKLRLRLTKRKEEQPKKMDQ---ISERESVV--DHRRVEDLLQFINSSETKPVSSTRAA 869
+EK+R + K ++ K DQ I E+E + ++ + + I E K
Sbjct: 487 QEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMM 546
Query: 870 KRARHKQRKLEEKARLEAEARAREHLHLQEEQRRREEEEDEEEEEDRFKEEFQRLQELQK 929
+ K + EEK + + + R +E ++E++ RE++E E+E++ E+ ++++E ++
Sbjct: 547 QEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEE 606
Query: 930 LRAVKKKKK-ERPSKDC 945
+ +++K E+ K C
Sbjct: 607 MMQEQEEKMWEQEEKMC 623
Score = 40.8 bits (94), Expect = 0.008
Identities = 59/311 (18%), Positives = 126/311 (40%), Gaps = 38/311 (12%)
Query: 821 RLTKRKEEQP-KKMDQISERESVVDHRRVEDLLQFINSSETKPVSSTRAAKRARHKQRKL 879
RL +++EE+ ++ ++I E E ++++ + I E K +R +
Sbjct: 293 RLNQQQEEKMWRQEEKIQEWEE-----KIQEQEEKIREQEEKIREQEEKMRRQEEMMWEK 347
Query: 880 EEKARLEAE--------ARAREHLHLQEEQRRREEEEDEEEEEDRFKEEFQRLQELQKLR 931
EEK R + E R E + ++E++ RE EE E+E + +E+ ++ QE +K+R
Sbjct: 348 EEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQE-KIREQEEKRQEEEKIR 406
Query: 932 AVKKKKKERPSKDCPKLDMLTRNFQAATESVPNSGNIHNGSLEQTEEPETSSHSPSRHMN 991
++K++E+ +K + + + + E EQ + E M
Sbjct: 407 E-QEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMW 465
Query: 992 HSEPRPGLGADGDAADPVDTRDSKFLLPKEVNGKQHEPLSFFFDIMQHHKEGNGKQKLR- 1050
E + R+ + + ++ + E + Q K ++K+
Sbjct: 466 RQEEK--------------IREQEEIWRQKEKMHEQEKIR-----KQEEKVWRQEEKMHD 506
Query: 1051 QTSKASSEPARRPTEPPKATEGQSKPRAQTESKAKVVDLMSITEQK--REERKVNSNNNN 1108
Q K + + + K E + K R Q E + ++M E+K +E K+
Sbjct: 507 QEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKM 566
Query: 1109 KKQLNHIKDEK 1119
++Q I++++
Sbjct: 567 RRQEEKIREQE 577
Score = 40.0 bits (92), Expect = 0.014
Identities = 33/129 (25%), Positives = 60/129 (46%), Gaps = 5/129 (3%)
Query: 813 EMREKLRLRLTKRKEEQPKKMDQISERESVVDHRRVEDLLQFINSSETKPVSSTRAAKRA 872
E EK+R + +E++ K +Q + + RR E+ I E K +
Sbjct: 534 EQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEK---IREQEEKIREQKEKIREQ 590
Query: 873 RHKQRKLEEKARLEAEA--RAREHLHLQEEQRRREEEEDEEEEEDRFKEEFQRLQELQKL 930
K + EEK R + E E + QEE+ +EE+ +E+EE ++E + ++ +L
Sbjct: 591 EEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRL 650
Query: 931 RAVKKKKKE 939
R ++K +E
Sbjct: 651 RQQEEKMQE 659
Score = 38.5 bits (88), Expect = 0.040
Identities = 21/48 (43%), Positives = 23/48 (47%), Gaps = 3/48 (6%)
Query: 433 PPGHQFLSPEKPTHPALHLYPHIHGHVPLHTVPHLPRPLIHPTLYATP 480
P H P PTHP L +PH+ H L T PHLP HP L P
Sbjct: 5 PQPHLPTHPHLPTHPHLPTHPHLPTHPHLPTHPHLP---THPHLPTHP 49
Score = 37.7 bits (86), Expect = 0.068
Identities = 56/325 (17%), Positives = 124/325 (38%), Gaps = 74/325 (22%)
Query: 822 LTKRKEEQPKKM--DQISERESVVDHRRVEDLLQFINSSETKPVSSTRAAKRARHKQRKL 879
LTK ++ ++ + I++ E + ++++ LQ + S +++ + + KR + + L
Sbjct: 198 LTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLL 257
Query: 880 EEKARLEAEARAREHL-------------------------HLQEEQRRREEEEDEEEEE 914
+ +L+AEA +HL QEE+ R+EE+ +E EE
Sbjct: 258 LPQQQLQAEA---DHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEE 314
Query: 915 DRFKEEFQRLQELQKLRAVKKKKKERPSKDCPKLDMLTRNFQAATESVPNSGNIHNGSLE 974
++E + ++ +K+R ++K + + K + + R + E + E
Sbjct: 315 KIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWE 374
Query: 975 QTEEPETSSHSPSRHMNHSEPRPGLGADGDAADPVDTRDSKFLLPKEVNGKQHEPLSFFF 1034
+ E+ +E+ K HE
Sbjct: 375 KEEK----------------------------------------IRELEEKMHEQEK--- 391
Query: 1035 DIMQHHKEGNGKQKLRQTSKASSEPARRPTEPPKATEGQSKPRAQTESKAKVVDLMSITE 1094
I + ++ ++K+R+ K + A+ + K E + K R Q + + + + E
Sbjct: 392 -IREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQE 450
Query: 1095 QKREERKVNSNNNNKKQLNHIKDEK 1119
+ REE K +Q I++++
Sbjct: 451 KIREEEKRQEQEEMWRQEEKIREQE 475
Score = 37.4 bits (85), Expect = 0.088
Identities = 36/140 (25%), Positives = 65/140 (46%), Gaps = 15/140 (10%)
Query: 817 KLRLRLTKRKEEQPKKMDQISERESVVDHRRVEDLLQFINSSETKPVSSTRAAKRARHKQ 876
+L ++ KRK E+ K + + ++ DH E LQ +++ V R +Q
Sbjct: 241 QLNVKELKRKLERAKLLLPQQQLQAEADHLGKE--LQSVSAKLQAQVEENELWNRLNQQQ 298
Query: 877 R----KLEEKAR------LEAEARAREH---LHLQEEQRRREEEEDEEEEEDRFKEEFQR 923
+ EEK + E E + RE + QEE+ RR+EE E+EE ++E
Sbjct: 299 EEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMM 358
Query: 924 LQELQKLRAVKKKKKERPSK 943
++ +K+R +++ E+ K
Sbjct: 359 WEKEEKMRRLEEMMWEKEEK 378
Score = 37.4 bits (85), Expect = 0.088
Identities = 26/118 (22%), Positives = 54/118 (45%), Gaps = 4/118 (3%)
Query: 813 EMREKLRLRLTKRKEEQPKKMDQISERESVVDHRRVEDLLQFINSSETKPVSSTRAAKRA 872
E EK+ + K +E++ + + RE ++ + + I E K +
Sbjct: 548 EQEEKMGEQEEKMQEQEKMRRQEEKIREQ---EEKIREQKEKIREQEEKIWEQEEKIREQ 604
Query: 873 RHKQRKLEEKARLEAEARAREHLHLQE-EQRRREEEEDEEEEEDRFKEEFQRLQELQK 929
++ EEK + E + +QE E++ R +EE E+E R +++ +++QE Q+
Sbjct: 605 EEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 662
Score = 33.1 bits (74), Expect = 1.7
Identities = 23/70 (32%), Positives = 26/70 (37%), Gaps = 6/70 (8%)
Query: 441 PEKPTHPALHLYPHIHGHVPLHTVPHLPRPLIHPTLYATPPFTHSKALPPAPVQNHTNKH 500
P PTHP L +PH L T PHLP PT P H P + +K
Sbjct: 7 PHLPTHPHLPTHPH------LPTHPHLPTHPHLPTHPHLPTHPHLPTHPMMSKETRQSKL 60
Query: 501 QVFNASLQDH 510
L DH
Sbjct: 61 AEAKEQLTDH 70
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform 8
[Homo sapiens]
Length = 780
Score = 53.1 bits (126), Expect = 2e-06
Identities = 76/390 (19%), Positives = 152/390 (38%), Gaps = 78/390 (20%)
Query: 813 EMREKLRLRLTKRKEEQPKKMDQISERESVVDH----------RRVEDLLQFINSSETKP 862
E EK ++ K +++ K D + E E + DH R ED ++ +
Sbjct: 25 EQEEKAEIKRLKNSDDRDSKRDSLEEGE-LRDHCMEITIRNSPYRREDSMEDRGEED--- 80
Query: 863 VSSTRAAKRARHKQRKLEEKARLEAEARAREHLHLQEEQRRREEEEDEEEEEDRFKEEFQ 922
+ A K + RK + R + + + ++H ++E++R E + EE+D+ + E++
Sbjct: 81 --DSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWE 138
Query: 923 --------------------------RLQELQKLRAVKKKKKERPSKDCPKLDMLTRNFQ 956
RL++L++ R ++K +E+ + + + R +
Sbjct: 139 RQKRREMAREHSRRERGNDGVCLFRDRLEQLERKRERERKMREQQKE---QREQKERERR 195
Query: 957 AATESVPNSGNIHNGSLEQTEEPETSSHSPSRHMNHSEPRPGLGAD--GDAADPVDTRDS 1014
A + +T + S + H + S PRP GD PV
Sbjct: 196 AEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPV----- 250
Query: 1015 KFLLPKEVNGKQHEPLSFFFDIMQHHKEGNGKQKLRQTSKASSEPARRPTEPPKATEGQS 1074
KE ++ + LS DI R+TS A S A E +E +
Sbjct: 251 -----KEEKMEERDLLSDLQDISDSE---------RKTSSAESSSA----ESGSGSEEEE 292
Query: 1075 KPRAQTESKAKVVDLMSITEQKREERKVNSNNNNKKQLNHIKDEKSNPTPMEPTSPGEHQ 1134
+ + E + + E++ EE + + +N+++ +E S E S E +
Sbjct: 293 EEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSE----EEMSEDEER 348
Query: 1135 QNSK--LVLAES--PQPKGKNKKNKKKKGD 1160
+N LV+ ES + G++++ +++ G+
Sbjct: 349 ENENHLLVVPESRFDRDSGESEEAEEEVGE 378
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 53.1 bits (126), Expect = 2e-06
Identities = 37/121 (30%), Positives = 61/121 (50%), Gaps = 5/121 (4%)
Query: 822 LTKRKEEQPKKMDQISERESVVDHRRVEDLLQFINSSETKPVSSTRAAKRARHKQRKLEE 881
L K+KEE+ +++ + +E + + + R E Q E + R + R ++R+L E
Sbjct: 664 LQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERR--EQERREQERREQERQLAE 721
Query: 882 KARLEAEARAREHLHLQEEQ---RRREEEEDEEEEEDRFKEEFQRLQELQKLRAVKKKKK 938
+ R + R + LQE + R ++E+ E EE + KEE QRL E Q +KK K
Sbjct: 722 QERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAK 781
Query: 939 E 939
E
Sbjct: 782 E 782
Score = 52.8 bits (125), Expect = 2e-06
Identities = 35/142 (24%), Positives = 74/142 (52%), Gaps = 7/142 (4%)
Query: 804 AAPTSRNYAEMREKLRLRLTKRKEEQPKKMDQISERESVVDHRRVEDLLQFINSSETKPV 863
A ++ A ++ + +++EE+ +++ + + E + RR ++LLQ E + +
Sbjct: 619 AEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEE---EERRHQELLQKKKEEEQERL 675
Query: 864 SSTRAAKR-ARHKQRKLEEKARLEAEARAREHLHLQEEQRRREEEEDEEEEEDRFKEEFQ 922
AKR A ++++ E+ R E E R +E +E++RR +E + E+E R +E Q
Sbjct: 676 RKAAEAKRLAEQREQERREQERREQERREQER---REQERREQERQLAEQERRREQERLQ 732
Query: 923 RLQELQKLRAVKKKKKERPSKD 944
+ELQ+ + +KE+ ++
Sbjct: 733 AERELQEREKALRLQKEQLQRE 754
Score = 47.4 bits (111), Expect = 9e-05
Identities = 36/140 (25%), Positives = 68/140 (48%), Gaps = 18/140 (12%)
Query: 809 RNYAEMREKLRLRLTKR-KEEQPKKMDQISERESVVDHRRVED---LLQFINSSETKPVS 864
+ +A++ EK +R EE+ KK + E V R+ E+ L+++ E
Sbjct: 601 QKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEE----- 655
Query: 865 STRAAKRARHKQ----RKLEEKARLEAEARAREHLHLQEEQRRREEEEDEEEEEDRFKEE 920
+ RH++ +K EE+ RL A A+ +E++RR +E ++E E +E+
Sbjct: 656 -----EERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQ 710
Query: 921 FQRLQELQKLRAVKKKKKER 940
+R QE Q +++++ER
Sbjct: 711 ERREQERQLAEQERRREQER 730
Score = 46.6 bits (109), Expect = 1e-04
Identities = 40/149 (26%), Positives = 79/149 (53%), Gaps = 13/149 (8%)
Query: 809 RNYAEMREKLRLRLTK-RKEEQPKKMDQISER-ESVVDHRRVEDLLQFINSSE-TKPVSS 865
R E ++ RL K ++EE+ +K+ Q ER E + + ++ + +F E T+
Sbjct: 556 RQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKE 615
Query: 866 TRAA------KRARHKQRKLEEKARLEAEARAREHLHLQEEQRRREE--EEDEEEEEDRF 917
R A K A K ++E + + E EAR L +EE+RR +E ++ +EEE++R
Sbjct: 616 ERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERL 675
Query: 918 KE--EFQRLQELQKLRAVKKKKKERPSKD 944
++ E +RL E ++ +++++E+ ++
Sbjct: 676 RKAAEAKRLAEQREQERREQERREQERRE 704
Score = 38.9 bits (89), Expect = 0.030
Identities = 70/342 (20%), Positives = 131/342 (38%), Gaps = 36/342 (10%)
Query: 802 PPAAPTSRNYAEMREKLRLRLTKRKEEQPKKMDQISERESVVDHRRVEDLLQFINSSETK 861
P +AP S + ++ LR+ PK ER+ + + RR E+ Q
Sbjct: 508 PTSAPRSVMKSFIKRNTPLRM------DPKCSFVEKERQRLENLRRKEEAEQL------- 554
Query: 862 PVSSTRAAKRARHKQRKLEEKARLEAEARAREHLHLQEEQRRREEEEDEEEEEDRFKEEF 921
R K K+R+LEE +L+ E R R+ L Q R E+ +EE++ + +++F
Sbjct: 555 -----RRQKVEEDKRRRLEE-VKLKREERLRKVL-----QARERVEQMKEEKKKQIEQKF 603
Query: 922 QRLQELQKLRAVKKKKKERPSKDCPKLDMLTRNFQAATESVPNSGNIHNGSLEQTEEPET 981
++ E +K K+ER +++ K + + Q EE E
Sbjct: 604 AQIDE-----KTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEE-EE 657
Query: 982 SSHSPSRHMNHSEPRPGLGADGDAADPVDTRDSKFLLPKEVNGKQHEPLSFFFDIMQHHK 1041
H E + L +A + R+ + + ++ E + + +
Sbjct: 658 RRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQER 717
Query: 1042 EGNGKQKLRQTSKASSEPARRPTEPPKATEGQSKP-RAQTESKAKVVDLMSITE---QKR 1097
+ +++ R+ + +E R E KA Q + + + E K K + + E Q+
Sbjct: 718 QLAEQERRREQERLQAE--RELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEE 775
Query: 1098 EERKVNSNNNNKKQLNHIKDEKSNPTPMEPTSPGEHQQNSKL 1139
+E+K K LN D +S +P H+ K+
Sbjct: 776 QEKKAKEAAGASKALNVTVDVQSPACTSYQMTPQGHRAPPKI 817
Score = 34.3 bits (77), Expect = 0.75
Identities = 76/433 (17%), Positives = 156/433 (36%), Gaps = 60/433 (13%)
Query: 734 APPSVCSDPDCEGHRCENGVYDPQQDDGDESADEDSCSEHSSSTSTSTNQKEGKYCDCCY 793
A P ++P+ + N P D ++ + SS + S Q+E K
Sbjct: 382 AEPVAAAEPEVPENNGNNSW--PHNDTEIANSTPNPKPAASSPETPSAGQQEAKTDQA-- 437
Query: 794 CEFFGHGGPPAAPTSRNYAEMREKLRLRLTKRKEEQPKKMDQISERESVVDH------RR 847
GP P S A + + +++ EEQ + +++ S +
Sbjct: 438 ------DGPREPPQS---ARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKV 488
Query: 848 VEDLLQFINSSETKPV--SSTRAAKRARHKQRKLEEKARLEAEARAREHLHLQEEQRRRE 905
V L F+++ + + + T A + K R++ + E + E RR+
Sbjct: 489 VRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKCSFVEKERQRLENLRRK 548
Query: 906 EEEDEEEEEDRFKEEFQRLQELQKLRAVKKKKKERPSKDCPKLDMLTRNFQAATESVPNS 965
EE ++ + +++ +RL+E VK K++ER R A E V
Sbjct: 549 EEAEQLRRQKVEEDKRRRLEE------VKLKREER-----------LRKVLQARERVEQM 591
Query: 966 GNIHNGSLEQTEEPETSSHSPSRHMNHSEPRPGLGADGDAADPVDTRDSKFLLPKEVNGK 1025
+EQ ++ +E + A + V+ R K
Sbjct: 592 KEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEAR-----------RK 640
Query: 1026 QHEPLSFFFDIMQHHKEGNGKQKLRQTSKASSEPARRPTEPPKATEGQSKPRAQTESKAK 1085
Q E + Q +E ++ L++ + E R+ E + E + + R + E + +
Sbjct: 641 QEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQ 700
Query: 1086 VVDLMSITEQKREERKVNSNNNNKKQLNHIKDEKSNPTPMEPTSPGEHQQNSKLVLAESP 1145
E++ +ER+ ++QL +++ + E Q+ K + +
Sbjct: 701 --------ERREQERREQERREQERQL---AEQERRREQERLQAERELQEREKALRLQKE 749
Query: 1146 QPKGKNKKNKKKK 1158
Q + + ++ KKK+
Sbjct: 750 QLQRELEEKKKKE 762
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 53.1 bits (126), Expect = 2e-06
Identities = 37/121 (30%), Positives = 61/121 (50%), Gaps = 5/121 (4%)
Query: 822 LTKRKEEQPKKMDQISERESVVDHRRVEDLLQFINSSETKPVSSTRAAKRARHKQRKLEE 881
L K+KEE+ +++ + +E + + + R E Q E + R + R ++R+L E
Sbjct: 660 LQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERR--EQERREQERREQERQLAE 717
Query: 882 KARLEAEARAREHLHLQEEQ---RRREEEEDEEEEEDRFKEEFQRLQELQKLRAVKKKKK 938
+ R + R + LQE + R ++E+ E EE + KEE QRL E Q +KK K
Sbjct: 718 QERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAK 777
Query: 939 E 939
E
Sbjct: 778 E 778
Score = 52.8 bits (125), Expect = 2e-06
Identities = 35/142 (24%), Positives = 74/142 (52%), Gaps = 7/142 (4%)
Query: 804 AAPTSRNYAEMREKLRLRLTKRKEEQPKKMDQISERESVVDHRRVEDLLQFINSSETKPV 863
A ++ A ++ + +++EE+ +++ + + E + RR ++LLQ E + +
Sbjct: 615 AEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEE---EERRHQELLQKKKEEEQERL 671
Query: 864 SSTRAAKR-ARHKQRKLEEKARLEAEARAREHLHLQEEQRRREEEEDEEEEEDRFKEEFQ 922
AKR A ++++ E+ R E E R +E +E++RR +E + E+E R +E Q
Sbjct: 672 RKAAEAKRLAEQREQERREQERREQERREQER---REQERREQERQLAEQERRREQERLQ 728
Query: 923 RLQELQKLRAVKKKKKERPSKD 944
+ELQ+ + +KE+ ++
Sbjct: 729 AERELQEREKALRLQKEQLQRE 750
Score = 47.4 bits (111), Expect = 9e-05
Identities = 36/140 (25%), Positives = 68/140 (48%), Gaps = 18/140 (12%)
Query: 809 RNYAEMREKLRLRLTKR-KEEQPKKMDQISERESVVDHRRVED---LLQFINSSETKPVS 864
+ +A++ EK +R EE+ KK + E V R+ E+ L+++ E
Sbjct: 597 QKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEE----- 651
Query: 865 STRAAKRARHKQ----RKLEEKARLEAEARAREHLHLQEEQRRREEEEDEEEEEDRFKEE 920
+ RH++ +K EE+ RL A A+ +E++RR +E ++E E +E+
Sbjct: 652 -----EERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQ 706
Query: 921 FQRLQELQKLRAVKKKKKER 940
+R QE Q +++++ER
Sbjct: 707 ERREQERQLAEQERRREQER 726
Score = 46.6 bits (109), Expect = 1e-04
Identities = 40/149 (26%), Positives = 79/149 (53%), Gaps = 13/149 (8%)
Query: 809 RNYAEMREKLRLRLTK-RKEEQPKKMDQISER-ESVVDHRRVEDLLQFINSSE-TKPVSS 865
R E ++ RL K ++EE+ +K+ Q ER E + + ++ + +F E T+
Sbjct: 552 RQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKE 611
Query: 866 TRAA------KRARHKQRKLEEKARLEAEARAREHLHLQEEQRRREE--EEDEEEEEDRF 917
R A K A K ++E + + E EAR L +EE+RR +E ++ +EEE++R
Sbjct: 612 ERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERL 671
Query: 918 KE--EFQRLQELQKLRAVKKKKKERPSKD 944
++ E +RL E ++ +++++E+ ++
Sbjct: 672 RKAAEAKRLAEQREQERREQERREQERRE 700
Score = 41.6 bits (96), Expect = 0.005
Identities = 81/447 (18%), Positives = 165/447 (36%), Gaps = 92/447 (20%)
Query: 734 APPSVCSDPDCEGHRCENGVYDPQQDDGDESADEDSCSEHSSSTSTSTNQKEGKYCDCCY 793
A P ++P+ + N P D ++ + SS + S Q+E K
Sbjct: 382 AEPVAAAEPEVPENNGNNSW--PHNDTEIANSTPNPKPAASSPETPSAGQQEAKTDQA-- 437
Query: 794 CEFFGHGGPPAAPTSRNYAEMREKLRLRLTKRKEEQPKKMDQISERESVVDH------RR 847
GP P S A + + +++ EEQ + +++ S +
Sbjct: 438 ------DGPREPPQS---ARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKV 488
Query: 848 VEDLLQFINSSETK-----PVSSTRAAKRARHKQR-------KLEEKARLEAEARAREHL 895
V L F+++ + P S+ R+ ++ K+ K +E+ RLE R E
Sbjct: 489 VRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAE 548
Query: 896 HLQ----EEQRRREEEEDEEEEEDRFKEEFQRLQELQKLRAVKKKKKERPSKDCPKLDML 951
L+ EE +RR EE + + E+R ++ Q + +++++ KKK+ E+ K +
Sbjct: 549 QLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQ------KFAQI 602
Query: 952 TRNFQAATESVPNSGNIHNGSLEQTEEPETSSHSPSRHMNHSEPRPGLGADGDAADPVDT 1011
+ A E E+ E + + ++ M E R
Sbjct: 603 DEKTEKAKE-------------ERLAEEKAKKKAAAKKMEEVEAR--------------- 634
Query: 1012 RDSKFLLPKEVNGKQHEPLSFFFDIMQHHKEGNGKQKLRQTSKASSEPARRPTEPPKATE 1071
KQ E + Q +E ++ L++ + E R+ E + E
Sbjct: 635 ------------RKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAE 682
Query: 1072 GQSKPRAQTESKAKVVDLMSITEQKREERKVNSNNNNKKQLNHIKDEKSNPTPMEPTSPG 1131
+ + R + E + + E++ +ER+ ++QL +++ +
Sbjct: 683 QREQERREQERREQ--------ERREQERREQERREQERQL---AEQERRREQERLQAER 731
Query: 1132 EHQQNSKLVLAESPQPKGKNKKNKKKK 1158
E Q+ K + + Q + + ++ KKK+
Sbjct: 732 ELQEREKALRLQKEQLQRELEEKKKKE 758
Score = 39.7 bits (91), Expect = 0.018
Identities = 66/319 (20%), Positives = 124/319 (38%), Gaps = 31/319 (9%)
Query: 826 KEEQPKKMD-QISERESVVDHRRVEDLLQFINSSETKPVSSTRAAKRARHKQRKLEEKAR 884
K P +MD + ER+ + + RR E+ Q R K K+R+LEE +
Sbjct: 521 KRNTPLRMDPKEKERQRLENLRRKEEAEQL------------RRQKVEEDKRRRLEE-VK 567
Query: 885 LEAEARAREHLHLQEEQRRREEEEDEEEEEDRFKEEFQRLQELQKLRAVKKKKKERPSKD 944
L+ E R R+ L Q R E+ +EE++ + +++F ++ E +K K+ER +++
Sbjct: 568 LKREERLRKVL-----QARERVEQMKEEKKKQIEQKFAQIDE-----KTEKAKEERLAEE 617
Query: 945 CPKLDMLTRNFQAATESVPNSGNIHNGSLEQTEEPETSSHSPSRHMNHSEPRPGLGADGD 1004
K + + Q EE E H E + L +
Sbjct: 618 KAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEE-EERRHQELLQKKKEEEQERLRKAAE 676
Query: 1005 AADPVDTRDSKFLLPKEVNGKQHEPLSFFFDIMQHHKEGNGKQKLRQTSKASSEPARRPT 1064
A + R+ + + ++ E + + ++ +++ R+ + +E R
Sbjct: 677 AKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAE--RELQ 734
Query: 1065 EPPKATEGQSKP-RAQTESKAKVVDLMSITE---QKREERKVNSNNNNKKQLNHIKDEKS 1120
E KA Q + + + E K K + + E Q+ +E+K K LN D +S
Sbjct: 735 EREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKALNVTVDVQS 794
Query: 1121 NPTPMEPTSPGEHQQNSKL 1139
+P H+ K+
Sbjct: 795 PACTSYQMTPQGHRAPPKI 813
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 52.4 bits (124), Expect = 3e-06
Identities = 59/271 (21%), Positives = 107/271 (39%), Gaps = 44/271 (16%)
Query: 821 RLTKRKEEQPKKMDQISERESVVDHRRVEDLLQFINSSETKPVSSTRAAKRARHKQRKLE 880
R KR+EE+ ++M++ + +R+++ L + K S +R R K+R+ E
Sbjct: 461 RARKRREEEERRMEEQRKAACAEKLKRLDEKLGILE----KQPSPEEIREREREKERERE 516
Query: 881 EKARLEAEARAREHLHLQEEQRRREEEEDEEEEEDRFKEEFQRLQELQKLRAVKKKKKER 940
++ E QE++R +E E+D E ++++ KE +E +K R ++K++K+
Sbjct: 517 KELEKE-----------QEQEREKEREKDRERQQEKEKE---LEKEQEKQREMEKERKQE 562
Query: 941 PSKDCPKLDMLTRNFQAATESVPNSG-NIHNGSLEQTEEPETSSHSPSRHMNHSEPRPGL 999
K+ + + Q E LE+ EP + P SE
Sbjct: 563 KEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESE----- 617
Query: 1000 GADGDAADPVDTRDSKFLLPKEVNGKQHEP------------LSFFF--------DIMQH 1039
+ +PV TR KE HE LS +F Q
Sbjct: 618 NSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQR 677
Query: 1040 HKEGNGKQKLRQTSKASSEPARRPTEPPKAT 1070
+E +Q+ +Q + P P++P +T
Sbjct: 678 QQEQMKQQQWQQQQQQGVLPQTVPSQPSSST 708
Score = 43.5 bits (101), Expect = 0.001
Identities = 28/110 (25%), Positives = 57/110 (51%), Gaps = 11/110 (10%)
Query: 813 EMREKLRLRLTKRKEEQPKKMDQISERESVVDHRRVEDLLQFINSSETKPVSSTRAAKRA 872
E+RE+ R + +R++E K+ +Q E+E D R ++ + K + + +R
Sbjct: 503 EIREREREKEREREKELEKEQEQEREKEREKDRERQQE--------KEKELEKEQEKQRE 554
Query: 873 RHKQRKLEEKARLEAEARAREHLHLQEEQRRREEEEDEEEEEDRFKEEFQ 922
K+RK E++ LE + + L +EQ E+E + E+E ++ +E+ +
Sbjct: 555 MEKERKQEKEKELERQKEKEKELQKMKEQ---EKECELEKEREKLEEKIE 601
Score = 43.1 bits (100), Expect = 0.002
Identities = 52/225 (23%), Positives = 88/225 (39%), Gaps = 17/225 (7%)
Query: 528 ISLWGSEVMNDKNWNPGTFLPDTISGSEILGPTLSETRPEALPPPSSNETPAVSDSKEKK 587
I +W + N+K + + LP + + G +++ P S+ P+ S S
Sbjct: 1706 IQVWNKKNANEKGRSQTSKLPPRFAKKQATGIQQAQSSASVPPLASAPLPPSTSASVPAS 1765
Query: 588 NAAKKKCLYNFQDAFMEAN--KVVMATSSATSSVSCTATTVQSSNSQFRVSSKRPPSVGD 645
+A A A +A A++S A+ + ++ VS+ P S
Sbjct: 1766 TSAPLPATLTPVPASTSAPVPASTLAPVLASTSAPVPASPLAPVSASASVSASVPASTSA 1825
Query: 646 VFHGISKEDHRHSAPA-----APRNSPTGL-----APLPALSPAALSPAALSPA---STP 692
I+ SAPA A ++P + A +P L+ A S +A +PA S+P
Sbjct: 1826 A--AITSSSAPASAPAPTPILASVSTPASVTILASASIPILASALASTSAPTPAPAASSP 1883
Query: 693 HLANLAAPSFPKTATTTPGFVDTRKSFCPAPLPPATDGSISAPPS 737
+ AP+ P +A T + + PAP P APP+
Sbjct: 1884 AAPVITAPTIPASAPTASVPLAPASASAPAPAPTPVSAPNPAPPA 1928
Score = 32.0 bits (71), Expect = 3.7
Identities = 41/169 (24%), Positives = 62/169 (36%), Gaps = 17/169 (10%)
Query: 343 SPQISSTSSS--SSEADDEEADGESSGEPPGAPKEDGVLGSRSPRTEESKADSPPPSYPT 400
+P ++STS+ +S A S P + + S +P A +P P+ P
Sbjct: 1791 APVLASTSAPVPASPLAPVSASASVSASVPASTSAAAITSSSAP------ASAPAPT-PI 1843
Query: 401 QQAEQAPNTCECHVCKQEASGLTPSAMTAGALP-PGHQFLSPEKPTHPALHLYPHIHGHV 459
+ P + + + + SA+ + + P P SP P A P I
Sbjct: 1844 LASVSTPASVT--ILASASIPILASALASTSAPTPAPAASSPAAPVITA----PTIPASA 1897
Query: 460 PLHTVPHLPRPLIHPTLYATPPFTHSKALPPAPVQNHTNKHQVFNASLQ 508
P +VP P P TP + A PPAP Q H+ LQ
Sbjct: 1898 PTASVPLAPASASAPAPAPTPVSAPNPA-PPAPAQTQAQTHKPVQNPLQ 1945
Score = 31.2 bits (69), Expect = 6.3
Identities = 27/168 (16%), Positives = 71/168 (42%), Gaps = 6/168 (3%)
Query: 1025 KQHEPLSFFFDIMQHHKEGNGKQKLRQTSKASSEPARRPTEPPKATEGQSKP-----RAQ 1079
+Q +S + + +E ++ Q A +E +R E E Q P R +
Sbjct: 450 RQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIRERER 509
Query: 1080 TESKAKVVDLMSITEQKREERKVNSNNNNKKQLNHIKDEKSNPTPMEPTSPGEHQQNSKL 1139
+ + + +L EQ+RE+ + +++ ++ E+ ME E ++ +
Sbjct: 510 EKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELER 569
Query: 1140 VLAESPQPKGKNKKNKKKKGDRVNNSIDDVFLPKDIDLD-SVDMDETE 1186
+ + + ++ K+ + ++ +++ P++ +L+ V+ E+E
Sbjct: 570 QKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESE 617
Score = 30.8 bits (68), Expect = 8.3
Identities = 27/82 (32%), Positives = 36/82 (43%), Gaps = 13/82 (15%)
Query: 658 SAPAAPRNSPTGLAPLPALSPAALSPAALSPASTPHLA-NLAAPSFPKTATTTPGFVDTR 716
+AP P ++PT PL A S +A +PA TP A N A P+ +T T V
Sbjct: 1889 TAPTIPASAPTASVPL-----APASASAPAPAPTPVSAPNPAPPAPAQTQAQTHKPVQN- 1942
Query: 717 KSFCPAPLPPATDGSISAPPSV 738
PL + S PPS+
Sbjct: 1943 ------PLQTTSQSSKQPPPSI 1958
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.127 0.370
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 56,518,962
Number of Sequences: 37866
Number of extensions: 3190095
Number of successful extensions: 42207
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 516
Number of HSP's successfully gapped in prelim test: 1277
Number of HSP's that attempted gapping in prelim test: 21572
Number of HSP's gapped (non-prelim): 11863
length of query: 1224
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1110
effective length of database: 13,930,794
effective search space: 15463181340
effective search space used: 15463181340
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.