Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 5174715

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5174715 transcription factor-like 1 [Homo sapiens]
         (364 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5174715 transcription factor-like 1 [Homo sapiens]                 742   0.0  
gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]      49   7e-06
gi|194272142 myosin IXB isoform 2 [Homo sapiens]                       46   5e-05
gi|33356170 myosin IXB isoform 1 [Homo sapiens]                        46   5e-05
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo...    45   1e-04
gi|187173290 troponin T1, skeletal, slow isoform b [Homo sapiens]      42   7e-04
gi|187173288 troponin T1, skeletal, slow isoform a [Homo sapiens]      42   7e-04
gi|87299628 biorientation of chromosomes in cell division 1-like...    42   9e-04
gi|217330570 EH domain binding protein 1 isoform 2 [Homo sapiens]      40   0.003
gi|217330568 EH domain binding protein 1 isoform 1 [Homo sapiens]      40   0.003
gi|145580615 KRI1 homolog [Homo sapiens]                               39   0.007
gi|161702986 ezrin [Homo sapiens]                                      39   0.010
gi|21614499 ezrin [Homo sapiens]                                       39   0.010
gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo sa...    39   0.010
gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo sa...    39   0.010
gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo sa...    39   0.010
gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo sap...    39   0.010
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom...    39   0.010
gi|15812186 F-box only protein 3 isoform 1 [Homo sapiens]              39   0.010
gi|51093859 calcium channel, voltage-dependent, T type, alpha 1I...    39   0.010
gi|21361077 calcium channel, voltage-dependent, T type, alpha 1I...    39   0.010
gi|102467235 inner centromere protein antigens 135/155kDa isofor...    39   0.010
gi|102467242 inner centromere protein antigens 135/155kDa isofor...    39   0.010
gi|29244924 chromodomain helicase DNA binding protein 6 [Homo sa...    38   0.012
gi|7019419 guanine nucleotide binding protein-like 2 (nucleolar)...    38   0.016
gi|9994179 transcriptional regulator protein [Homo sapiens]            38   0.016
gi|93587342 voltage-gated sodium channel type 4 alpha [Homo sapi...    38   0.016
gi|17975763 myelin transcription factor 1 [Homo sapiens]               38   0.016
gi|21237805 SWI/SNF-related matrix-associated actin-dependent re...    38   0.016
gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo sa...    37   0.021

>gi|5174715 transcription factor-like 1 [Homo sapiens]
          Length = 364

 Score =  742 bits (1916), Expect = 0.0
 Identities = 364/364 (100%), Positives = 364/364 (100%)

Query: 1   MSLAGGRAPRKTAGNRLSGLLEAEEEDEFYQTTYGGFTEESGDDEYQGDQSDTEDEVDSD 60
           MSLAGGRAPRKTAGNRLSGLLEAEEEDEFYQTTYGGFTEESGDDEYQGDQSDTEDEVDSD
Sbjct: 1   MSLAGGRAPRKTAGNRLSGLLEAEEEDEFYQTTYGGFTEESGDDEYQGDQSDTEDEVDSD 60

Query: 61  FDIDEGDEPSSDGEAEEPRRKRRVVTKAYKEPLKSLRPRKVNTPAGSSQKAREEKALLPL 120
           FDIDEGDEPSSDGEAEEPRRKRRVVTKAYKEPLKSLRPRKVNTPAGSSQKAREEKALLPL
Sbjct: 61  FDIDEGDEPSSDGEAEEPRRKRRVVTKAYKEPLKSLRPRKVNTPAGSSQKAREEKALLPL 120

Query: 121 ELQDDGSDSRKSMRQSTAEHTRQTFLRVQERQGQSRRRKGPHCERPLTQEELLREAKITE 180
           ELQDDGSDSRKSMRQSTAEHTRQTFLRVQERQGQSRRRKGPHCERPLTQEELLREAKITE
Sbjct: 121 ELQDDGSDSRKSMRQSTAEHTRQTFLRVQERQGQSRRRKGPHCERPLTQEELLREAKITE 180

Query: 181 ELNLRSLETYERLEADKKKQVHKKRKCPGPIITYHSVTVPLVGEPGPKEENVDIEGLDPA 240
           ELNLRSLETYERLEADKKKQVHKKRKCPGPIITYHSVTVPLVGEPGPKEENVDIEGLDPA
Sbjct: 181 ELNLRSLETYERLEADKKKQVHKKRKCPGPIITYHSVTVPLVGEPGPKEENVDIEGLDPA 240

Query: 241 PSVSALTPHAGTGPVNPPARCSRTFITFSDDATFEEWFPQGRPPKVPVREVCPVTHRPAL 300
           PSVSALTPHAGTGPVNPPARCSRTFITFSDDATFEEWFPQGRPPKVPVREVCPVTHRPAL
Sbjct: 241 PSVSALTPHAGTGPVNPPARCSRTFITFSDDATFEEWFPQGRPPKVPVREVCPVTHRPAL 300

Query: 301 YRDPVTDIPYATARAFKIIREAYKKYITAHGLPPTASALGPGPPPPEPLPGSGPRALRQK 360
           YRDPVTDIPYATARAFKIIREAYKKYITAHGLPPTASALGPGPPPPEPLPGSGPRALRQK
Sbjct: 301 YRDPVTDIPYATARAFKIIREAYKKYITAHGLPPTASALGPGPPPPEPLPGSGPRALRQK 360

Query: 361 IVIK 364
           IVIK
Sbjct: 361 IVIK 364


>gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]
          Length = 1390

 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 35/101 (34%), Positives = 51/101 (50%), Gaps = 14/101 (13%)

Query: 7   RAPRKTAGNRLSGLLEAEEEDEFYQTTYGGFTEESGDDEYQGDQSDTEDEVDSDFDIDEG 66
           R   +T  N+  G +E+ EE E  +       E+ G+DE   D+ D +D+ D D D DE 
Sbjct: 229 RTDEETTDNQ-EGSVESSEEGEDQEH------EDDGEDE--DDEDDDDDDDDDDDDDDED 279

Query: 67  DEPSSDGEAEEPRR---KRRVVTKAYKEPLKSLRPRKVNTP 104
           DE   DGE E  +R   ++R  T  Y+ PL+  +PR    P
Sbjct: 280 DEDEEDGEEENQKRYYLRQRKATVYYQAPLE--KPRHQRKP 318


>gi|194272142 myosin IXB isoform 2 [Homo sapiens]
          Length = 2022

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 65/269 (24%), Positives = 101/269 (37%), Gaps = 31/269 (11%)

Query: 2    SLAGGRAPRKTAGNRLSGLLEAEEEDEFYQTTYGGFTEESGDDEYQGDQSDTEDEVDSDF 61
            SL  G   RK+    +S   +AEE++           EE G  +  G Q   E       
Sbjct: 1033 SLCRGHLQRKSFSQMISEKQKAEEKEREALEAARAGAEEGGQGQAAGGQQVAE------- 1085

Query: 62   DIDEGDEPSSDGE--AEEPRRKRRVVTKAYKEPLKSLRPRKVNTPAGSSQKAREEKALLP 119
               +G EP+ DG   A EP      V  + + PL+   P K       +   ++  A   
Sbjct: 1086 ---QGPEPAEDGGHLASEPE-----VQPSDRSPLEHSSPEKEAPSPEKTLPPQKTVAAES 1137

Query: 120  LELQDDGSDSRKSMRQSTAEHTRQTFLRVQERQGQSRRRKGPHCERPLTQEE---LLREA 176
             E      + R+S RQ   EH +     +Q  + +S  R+     R +TQE+   LL + 
Sbjct: 1138 HEKVPSSREKRESRRQRGLEHVKFQNKHIQSCKEESALREP---SRRVTQEQGVSLLEDK 1194

Query: 177  KIT-EELNLRSLETYERLEADKKKQVHKKRKCPGPIITYHSVTVPLVGEPGPKEEN---- 231
            K + E+  L  +ET     + K+     +    G +      T+P  G P P +      
Sbjct: 1195 KESREDETLLVVETEAENTSQKQPTEQPQAMAVGKVSEETEKTLP-SGSPRPGQLERPTS 1253

Query: 232  --VDIEGLDPAPSVSALTPHAGTGPVNPP 258
              +D     PAP  +  TP   + P   P
Sbjct: 1254 LALDSRVSPPAPGSAPETPEDKSKPCGSP 1282


>gi|33356170 myosin IXB isoform 1 [Homo sapiens]
          Length = 2157

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 65/269 (24%), Positives = 101/269 (37%), Gaps = 31/269 (11%)

Query: 2    SLAGGRAPRKTAGNRLSGLLEAEEEDEFYQTTYGGFTEESGDDEYQGDQSDTEDEVDSDF 61
            SL  G   RK+    +S   +AEE++           EE G  +  G Q   E       
Sbjct: 1033 SLCRGHLQRKSFSQMISEKQKAEEKEREALEAARAGAEEGGQGQAAGGQQVAE------- 1085

Query: 62   DIDEGDEPSSDGE--AEEPRRKRRVVTKAYKEPLKSLRPRKVNTPAGSSQKAREEKALLP 119
               +G EP+ DG   A EP      V  + + PL+   P K       +   ++  A   
Sbjct: 1086 ---QGPEPAEDGGHLASEPE-----VQPSDRSPLEHSSPEKEAPSPEKTLPPQKTVAAES 1137

Query: 120  LELQDDGSDSRKSMRQSTAEHTRQTFLRVQERQGQSRRRKGPHCERPLTQEE---LLREA 176
             E      + R+S RQ   EH +     +Q  + +S  R+     R +TQE+   LL + 
Sbjct: 1138 HEKVPSSREKRESRRQRGLEHVKFQNKHIQSCKEESALREP---SRRVTQEQGVSLLEDK 1194

Query: 177  KIT-EELNLRSLETYERLEADKKKQVHKKRKCPGPIITYHSVTVPLVGEPGPKEEN---- 231
            K + E+  L  +ET     + K+     +    G +      T+P  G P P +      
Sbjct: 1195 KESREDETLLVVETEAENTSQKQPTEQPQAMAVGKVSEETEKTLP-SGSPRPGQLERPTS 1253

Query: 232  --VDIEGLDPAPSVSALTPHAGTGPVNPP 258
              +D     PAP  +  TP   + P   P
Sbjct: 1254 LALDSRVSPPAPGSAPETPEDKSKPCGSP 1282


>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
           sapiens]
          Length = 2168

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 39/132 (29%), Positives = 56/132 (42%), Gaps = 9/132 (6%)

Query: 22  EAEEEDEFYQTTYGGFTEESGDDEYQGD---QSDTEDEVDSDFDIDEGDEPSSDGEAEEP 78
           E EEED+  +       +ES D + + D   +SDTE   + D D  + DE  SD E E+ 
Sbjct: 609 EDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDDDKDQDESDSDTEGEKT 668

Query: 79  RRKRRVVTKAYKEPLKSL----RPRKVN--TPAGSSQKAREEKALLPLELQDDGSDSRKS 132
             K    T + K P  SL     PR ++     GS+  A   ++  P  L    S    S
Sbjct: 669 SMKLNKTTSSVKSPSMSLTGHSTPRNLHIAKAPGSAPAALCSESQSPAFLGTSSSTLTSS 728

Query: 133 MRQSTAEHTRQT 144
               T++  R T
Sbjct: 729 PHSGTSKRRRVT 740



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 22/74 (29%), Positives = 34/74 (45%), Gaps = 6/74 (8%)

Query: 10   RKTAGNRLSGLLEAEEEDEFYQTTYGGFTEESGDDEYQGDQSDTEDEVDSDFDIDEGDEP 69
            +KT     SG ++  EE     T   G          +G  SD +D+ D D D D+GDE 
Sbjct: 1261 KKTGKRDTSGGIDLGEEQHPLGTPTPGRKRRR-----KGGDSDYDDDDDDDSD-DQGDED 1314

Query: 70   SSDGEAEEPRRKRR 83
              D E +E ++ ++
Sbjct: 1315 DEDEEDKEDKKGKK 1328



 Score = 30.0 bits (66), Expect = 3.4
 Identities = 34/174 (19%), Positives = 65/174 (37%), Gaps = 11/174 (6%)

Query: 22  EAEEEDEFYQTTYGGFTEESGDDEYQGDQSDTE-DEVDSDFDIDEGDEPSSDGEAE-EPR 79
           +A E      +  G  ++ S +     D  D E DE + D  I+E ++  SD E+E + +
Sbjct: 237 KAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEEEEDQSIEESEDDDSDSESEAQHK 296

Query: 80  RKRRVVTKAYKEPLKSLRPRKVNTPAGSSQKAREEKALLPLELQDDGSDSRKSMRQSTAE 139
              +V+     +P    +         +++KA+E++   PL L  +        +Q   +
Sbjct: 297 SNNQVLLHGISDPKADGQK--------ATEKAQEKRIHQPLPLASESQTHSFQSQQKQPQ 348

Query: 140 HTRQTFLRVQERQGQSRRRKGPHCERPLTQEELLREAKITEELNLRSLETYERL 193
              Q    + +           H    +    L+   K    +N    ETY +L
Sbjct: 349 VLSQQLPFIFQSSQAKEESVNKHTS-VIQSTGLVSNVKPLSLVNQAKKETYMKL 401


>gi|187173290 troponin T1, skeletal, slow isoform b [Homo sapiens]
          Length = 262

 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 43/163 (26%), Positives = 69/163 (42%), Gaps = 16/163 (9%)

Query: 40  ESGDDEYQGDQSDTEDEVDSDFDIDEGDEPSSDGEAEEPRRKRRVVTKAYKEPLKSLRPR 99
           ++ + EY+ +Q + E+  + + +  E  EP ++ E E P+  R VV       +    P 
Sbjct: 3   DTEEQEYEEEQPE-EEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKI----PE 57

Query: 100 KVNTPAGSSQKAREEKALLPLE-LQDDGSDSRKSMRQSTAEHTRQTFLRVQERQGQSRRR 158
                     + R EK LL L+ L D   + RK   +       +   R  ER  Q R R
Sbjct: 58  GERVDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFR 117

Query: 159 KGPHCERPLTQEELLREAKITEE-LNLRSLETYERLEADKKKQ 200
                    T++E  R+AK+ EE +     E  +R E D KK+
Sbjct: 118 ---------TEKERERQAKLAEEKMRKEEEEAKKRAEDDAKKK 151


>gi|187173288 troponin T1, skeletal, slow isoform a [Homo sapiens]
          Length = 278

 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 43/163 (26%), Positives = 69/163 (42%), Gaps = 16/163 (9%)

Query: 40  ESGDDEYQGDQSDTEDEVDSDFDIDEGDEPSSDGEAEEPRRKRRVVTKAYKEPLKSLRPR 99
           ++ + EY+ +Q + E+  + + +  E  EP ++ E E P+  R VV       +    P 
Sbjct: 3   DTEEQEYEEEQPE-EEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKI----PE 57

Query: 100 KVNTPAGSSQKAREEKALLPLE-LQDDGSDSRKSMRQSTAEHTRQTFLRVQERQGQSRRR 158
                     + R EK LL L+ L D   + RK   +       +   R  ER  Q R R
Sbjct: 58  GERVDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFR 117

Query: 159 KGPHCERPLTQEELLREAKITEE-LNLRSLETYERLEADKKKQ 200
                    T++E  R+AK+ EE +     E  +R E D KK+
Sbjct: 118 ---------TEKERERQAKLAEEKMRKEEEEAKKRAEDDAKKK 151


>gi|87299628 biorientation of chromosomes in cell division 1-like
           [Homo sapiens]
          Length = 3051

 Score = 42.0 bits (97), Expect = 9e-04
 Identities = 50/216 (23%), Positives = 90/216 (41%), Gaps = 27/216 (12%)

Query: 7   RAPRKTAGNRLSGLLEAEEEDEFYQTTYGGFTEESGDDEYQGDQS----DTEDEVDSDFD 62
           + P +   N+   +   +E+     +   G T+ +    +  D S    DTE+EV +   
Sbjct: 373 KLPSEKNSNKAKTVEGTKEDFSLIDSDVDGLTDITVSSVHTSDLSSFEEDTEEEVVTSDS 432

Query: 63  IDEGDEPSSDGEAEEPRRKRRVVTKAYKEPLKSLRPRKVNTPAGSSQKAREEKALLPLEL 122
           ++EG+  S D E  +  + +   + + +   KS+R   V+ P   S+   +    L +E 
Sbjct: 433 MEEGEITSDDEEKNKQNKTKTQTSDSSEGKTKSVRHAYVHKPYLYSKYYSDSDDELTVE- 491

Query: 123 QDDGSDSRKSMRQSTAEHTRQTFLRVQ---ERQGQSRRRKGPHCERPLTQEELLREAKIT 179
                      RQS A+   +  LR Q   E+  + R++K    +   T+ +  R +   
Sbjct: 492 ---------QRRQSIAKEKEERLLRRQINREKLEEKRKQKAEKTKSSKTKGQ-GRSSVDL 541

Query: 180 EELNLRSLE---------TYERLEADKKKQVHKKRK 206
           EE + +SLE           ER   +KK  + KKRK
Sbjct: 542 EESSTKSLEPKAARIKEVLKERKVLEKKVALSKKRK 577



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 13/24 (54%), Positives = 14/24 (58%)

Query: 333 PPTASALGPGPPPPEPLPGSGPRA 356
           PP      P PPPP P PG+GP A
Sbjct: 15  PPPPPQPQPQPPPPPPGPGAGPGA 38


>gi|217330570 EH domain binding protein 1 isoform 2 [Homo sapiens]
          Length = 1196

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 26/104 (25%), Positives = 52/104 (50%), Gaps = 4/104 (3%)

Query: 40  ESGDDEYQGDQSDTEDEVDSDFDIDEGDEPSS-DGEAEEPRRKRRVVTKAYKEPLKSLRP 98
           ++  DE    + DT +E+   F +  GDE ++ + + + P +  ++V    K+ L  ++P
Sbjct: 866 KASGDENDNIEIDTNEEIPEGFVVGGGDELTNLENDLDTPEQNSKLVDLKLKK-LLEVQP 924

Query: 99  RKVNTPAGSSQKAREEKALLPLELQDDGSDSRKSMRQSTAEHTR 142
           +  N+P+ ++QKA  E +    +++    D R    Q T E  R
Sbjct: 925 QVANSPSSAAQKAVTESS--EQDMKSGTEDLRTERLQKTTERFR 966


>gi|217330568 EH domain binding protein 1 isoform 1 [Homo sapiens]
          Length = 1231

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 26/104 (25%), Positives = 52/104 (50%), Gaps = 4/104 (3%)

Query: 40   ESGDDEYQGDQSDTEDEVDSDFDIDEGDEPSS-DGEAEEPRRKRRVVTKAYKEPLKSLRP 98
            ++  DE    + DT +E+   F +  GDE ++ + + + P +  ++V    K+ L  ++P
Sbjct: 901  KASGDENDNIEIDTNEEIPEGFVVGGGDELTNLENDLDTPEQNSKLVDLKLKK-LLEVQP 959

Query: 99   RKVNTPAGSSQKAREEKALLPLELQDDGSDSRKSMRQSTAEHTR 142
            +  N+P+ ++QKA  E +    +++    D R    Q T E  R
Sbjct: 960  QVANSPSSAAQKAVTESS--EQDMKSGTEDLRTERLQKTTERFR 1001


>gi|145580615 KRI1 homolog [Homo sapiens]
          Length = 709

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 21/71 (29%), Positives = 35/71 (49%), Gaps = 6/71 (8%)

Query: 10  RKTAGNRLSGLLEAEEEDEFYQTTYGGFTEESGDDEYQG------DQSDTEDEVDSDFDI 63
           RK  GN + GL E + ED+F    +    ++   DEY G       Q + E+ ++ D++ 
Sbjct: 375 RKVTGNEMLGLEEGDLEDDFDPAQHDQLMQKCFGDEYYGAVEEEKPQFEEEEGLEDDWNW 434

Query: 64  DEGDEPSSDGE 74
           D  D P  +G+
Sbjct: 435 DTWDGPEQEGD 445


>gi|161702986 ezrin [Homo sapiens]
          Length = 586

 Score = 38.5 bits (88), Expect = 0.010
 Identities = 43/156 (27%), Positives = 69/156 (44%), Gaps = 12/156 (7%)

Query: 58  DSDFDIDEGDEPSSDGEAEEPRRK--RRVVTKAYKEPLKSLRPRKVNTPAGSSQKA--RE 113
           D  F I   D+ + D     PR +  +R++          +R RK +T      KA  RE
Sbjct: 252 DKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRKPDTIEVQQMKAQARE 311

Query: 114 EKALLPLELQDDGSDSRKSMRQSTAEHTRQTFLRVQER---QGQSRRRKGPHCERPLTQE 170
           EK    LE Q   ++ +   R+ T E  ++  +R +E    + Q    K    ER L+++
Sbjct: 312 EKHQKQLERQQLETEKK---RRETVEREKEQMMREKEELMLRLQDYEEKTKKAERELSEQ 368

Query: 171 ELLREAKITEELNLRSLETYERLEADKKKQVHKKRK 206
             ++ A   EE   R+ E  ERLEAD+   +  K +
Sbjct: 369 --IQRALQLEEERKRAQEEAERLEADRMAALRAKEE 402


>gi|21614499 ezrin [Homo sapiens]
          Length = 586

 Score = 38.5 bits (88), Expect = 0.010
 Identities = 43/156 (27%), Positives = 69/156 (44%), Gaps = 12/156 (7%)

Query: 58  DSDFDIDEGDEPSSDGEAEEPRRK--RRVVTKAYKEPLKSLRPRKVNTPAGSSQKA--RE 113
           D  F I   D+ + D     PR +  +R++          +R RK +T      KA  RE
Sbjct: 252 DKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRKPDTIEVQQMKAQARE 311

Query: 114 EKALLPLELQDDGSDSRKSMRQSTAEHTRQTFLRVQER---QGQSRRRKGPHCERPLTQE 170
           EK    LE Q   ++ +   R+ T E  ++  +R +E    + Q    K    ER L+++
Sbjct: 312 EKHQKQLERQQLETEKK---RRETVEREKEQMMREKEELMLRLQDYEEKTKKAERELSEQ 368

Query: 171 ELLREAKITEELNLRSLETYERLEADKKKQVHKKRK 206
             ++ A   EE   R+ E  ERLEAD+   +  K +
Sbjct: 369 --IQRALQLEEERKRAQEEAERLEADRMAALRAKEE 402


>gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo
           sapiens]
          Length = 1297

 Score = 38.5 bits (88), Expect = 0.010
 Identities = 45/170 (26%), Positives = 79/170 (46%), Gaps = 20/170 (11%)

Query: 40  ESGDDEYQGDQSDTEDEVDSDFDIDEGDEPSS----DGEAEEPRRKRRVVTKAYKEPLKS 95
           E  + EY+   S+ E+E +      +  EPSS     GE+   R   R+   A KE  ++
Sbjct: 315 EKDETEYEYSGSEEEEEEN------DSGEPSSILNLPGESTLRRDFLRLQL-ANKERSEA 367

Query: 96  LRPRKVNTPAGSSQKAREEKALLPLELQDDGSDSRKSMRQSTAEHTRQTFLRVQERQGQS 155
           LR +++       ++  E K  L  E Q    + ++  R+   +  R+  LR Q+ + Q 
Sbjct: 368 LRRQQLEQ---QQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQR 424

Query: 156 RRRKGPHCERPLTQEELLREAKITEELNLRSLETYER-LEADKKKQVHKK 204
           R     H E  + +EE  R A+  +E   R LE  +R LE  +++ +H++
Sbjct: 425 R-----HYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQ 469


>gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo
           sapiens]
          Length = 1305

 Score = 38.5 bits (88), Expect = 0.010
 Identities = 45/170 (26%), Positives = 79/170 (46%), Gaps = 20/170 (11%)

Query: 40  ESGDDEYQGDQSDTEDEVDSDFDIDEGDEPSS----DGEAEEPRRKRRVVTKAYKEPLKS 95
           E  + EY+   S+ E+E +      +  EPSS     GE+   R   R+   A KE  ++
Sbjct: 315 EKDETEYEYSGSEEEEEEN------DSGEPSSILNLPGESTLRRDFLRLQL-ANKERSEA 367

Query: 96  LRPRKVNTPAGSSQKAREEKALLPLELQDDGSDSRKSMRQSTAEHTRQTFLRVQERQGQS 155
           LR +++       ++  E K  L  E Q    + ++  R+   +  R+  LR Q+ + Q 
Sbjct: 368 LRRQQLEQ---QQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQR 424

Query: 156 RRRKGPHCERPLTQEELLREAKITEELNLRSLETYER-LEADKKKQVHKK 204
           R     H E  + +EE  R A+  +E   R LE  +R LE  +++ +H++
Sbjct: 425 R-----HYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQ 469


>gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo
           sapiens]
          Length = 1352

 Score = 38.5 bits (88), Expect = 0.010
 Identities = 45/170 (26%), Positives = 79/170 (46%), Gaps = 20/170 (11%)

Query: 40  ESGDDEYQGDQSDTEDEVDSDFDIDEGDEPSS----DGEAEEPRRKRRVVTKAYKEPLKS 95
           E  + EY+   S+ E+E +      +  EPSS     GE+   R   R+   A KE  ++
Sbjct: 315 EKDETEYEYSGSEEEEEEN------DSGEPSSILNLPGESTLRRDFLRLQL-ANKERSEA 367

Query: 96  LRPRKVNTPAGSSQKAREEKALLPLELQDDGSDSRKSMRQSTAEHTRQTFLRVQERQGQS 155
           LR +++       ++  E K  L  E Q    + ++  R+   +  R+  LR Q+ + Q 
Sbjct: 368 LRRQQLEQ---QQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQR 424

Query: 156 RRRKGPHCERPLTQEELLREAKITEELNLRSLETYER-LEADKKKQVHKK 204
           R     H E  + +EE  R A+  +E   R LE  +R LE  +++ +H++
Sbjct: 425 R-----HYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQ 469


>gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo
           sapiens]
          Length = 1360

 Score = 38.5 bits (88), Expect = 0.010
 Identities = 45/170 (26%), Positives = 79/170 (46%), Gaps = 20/170 (11%)

Query: 40  ESGDDEYQGDQSDTEDEVDSDFDIDEGDEPSS----DGEAEEPRRKRRVVTKAYKEPLKS 95
           E  + EY+   S+ E+E +      +  EPSS     GE+   R   R+   A KE  ++
Sbjct: 315 EKDETEYEYSGSEEEEEEN------DSGEPSSILNLPGESTLRRDFLRLQL-ANKERSEA 367

Query: 96  LRPRKVNTPAGSSQKAREEKALLPLELQDDGSDSRKSMRQSTAEHTRQTFLRVQERQGQS 155
           LR +++       ++  E K  L  E Q    + ++  R+   +  R+  LR Q+ + Q 
Sbjct: 368 LRRQQLEQ---QQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQR 424

Query: 156 RRRKGPHCERPLTQEELLREAKITEELNLRSLETYER-LEADKKKQVHKK 204
           R     H E  + +EE  R A+  +E   R LE  +R LE  +++ +H++
Sbjct: 425 R-----HYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQ 469


>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
            sapiens]
          Length = 1152

 Score = 38.5 bits (88), Expect = 0.010
 Identities = 25/70 (35%), Positives = 35/70 (50%), Gaps = 1/70 (1%)

Query: 14   GNRLSGLLEAEEEDEFYQTTYG-GFTEESGDDEYQGDQSDTEDEVDSDFDIDEGDEPSSD 72
            G    G  E EEE E  +   G G  EE G+ E + +  + E E + +   +EG+E   +
Sbjct: 990  GEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKE 1049

Query: 73   GEAEEPRRKR 82
            GE EE RR R
Sbjct: 1050 GEGEENRRNR 1059



 Score = 33.5 bits (75), Expect = 0.31
 Identities = 18/60 (30%), Positives = 30/60 (50%)

Query: 22  EAEEEDEFYQTTYGGFTEESGDDEYQGDQSDTEDEVDSDFDIDEGDEPSSDGEAEEPRRK 81
           E E E    +   GG  E    +E +G++ + E+E + + +  EG+E   +GE EE   K
Sbjct: 798 EEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGK 857



 Score = 33.1 bits (74), Expect = 0.40
 Identities = 37/166 (22%), Positives = 63/166 (37%), Gaps = 21/166 (12%)

Query: 22  EAEEEDEFYQTTYGGFTEESGDDEY------QGDQSDTEDEVDSDFDIDEGDEPSSDGEA 75
           E +E ++ +Q       EE G++E+      +GD+ + E++     +  EG+E   + E 
Sbjct: 711 EQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREK 770

Query: 76  EEPRRKRRVVTKAYKEPLKSLRPRKVNTPAGSSQKAREEKALLPLELQDDGSDSRKSMRQ 135
           EE  RK+    +A KE        K        +   EE      E ++ G      + +
Sbjct: 771 EEGERKKE--ERAGKE-------EKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEE 821

Query: 136 STAEHTRQTFLRVQERQGQSRRRKGPHCERPLTQEELLREAKITEE 181
              E         +E +G+    +G   E     EE   E K  EE
Sbjct: 822 GKGEREE------EEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEE 861



 Score = 33.1 bits (74), Expect = 0.40
 Identities = 23/80 (28%), Positives = 34/80 (42%), Gaps = 8/80 (10%)

Query: 6   GRAPRKTAGNRLSG--------LLEAEEEDEFYQTTYGGFTEESGDDEYQGDQSDTEDEV 57
           GR   K  G  + G          E EEE+   +   G   EE G+ E +  +   E+E 
Sbjct: 803 GRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEG 862

Query: 58  DSDFDIDEGDEPSSDGEAEE 77
           +     +EG+E   +GE EE
Sbjct: 863 EEGEGEEEGEEGEGEGEEEE 882



 Score = 31.6 bits (70), Expect = 1.2
 Identities = 17/56 (30%), Positives = 28/56 (50%)

Query: 22  EAEEEDEFYQTTYGGFTEESGDDEYQGDQSDTEDEVDSDFDIDEGDEPSSDGEAEE 77
           E EEE+   +   G   EE G+ + + +  + E E + +    EG+E   +GE EE
Sbjct: 834 EGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEE 889



 Score = 30.0 bits (66), Expect = 3.4
 Identities = 16/56 (28%), Positives = 28/56 (50%)

Query: 22  EAEEEDEFYQTTYGGFTEESGDDEYQGDQSDTEDEVDSDFDIDEGDEPSSDGEAEE 77
           E E E E  +    G  EE G+ E + ++ + + E + +    EG+E   +GE E+
Sbjct: 888 EEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGED 943



 Score = 29.6 bits (65), Expect = 4.4
 Identities = 40/212 (18%), Positives = 80/212 (37%), Gaps = 10/212 (4%)

Query: 6    GRAPRKTAGNRLSGLLEAEEEDEFYQTTYGGFTEESGDDEYQGDQSDTEDEVDSDFDIDE 65
            G    +  G    G  E EE +   +   G   EE G+ E + ++ + E E + + + +E
Sbjct: 917  GEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEE 976

Query: 66   G------DEPSSDGEAEEPRRKRRVVTKAYKEPLKSLRPRKVNTPAGSSQKAREEKALLP 119
            G      +E   +GE EE   +     +  +E        +     G  +    E     
Sbjct: 977  GEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEE 1036

Query: 120  LELQDDGSDSRKSMRQSTAEHTRQTFLRVQERQGQSRRRKGPHCERPLTQEELLREAKIT 179
             E +++G +  K   +   E  R+     +E +G+ +       ER    EE  + +KI 
Sbjct: 1037 EEGEEEGEEREK---EGEGEENRRNREEEEEEEGKYQETGEEENERQ-DGEEYKKVSKIK 1092

Query: 180  EELNLRSLETYERLEADKKKQVHKKRKCPGPI 211
              +     +TY++      +   K+++   P+
Sbjct: 1093 GSVKYGKHKTYQKKSVTNTQGNGKEQRSKMPV 1124



 Score = 28.9 bits (63), Expect = 7.6
 Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 5/64 (7%)

Query: 14  GNRLSGLLEAEEEDEFYQTTYGGFTEESGDDEYQGDQSDTEDEVDSDFDIDEGDEPSSDG 73
           G    G  E EEE E       G  E  G++E +G+  + E E   +   +EG+E   +G
Sbjct: 878 GEEEEGEGEGEEEGEGEGEEEEG--EGEGEEEGEGEGEEEEGEGKGE---EEGEEGEGEG 932

Query: 74  EAEE 77
           E EE
Sbjct: 933 EEEE 936



 Score = 28.5 bits (62), Expect = 9.9
 Identities = 19/55 (34%), Positives = 27/55 (49%), Gaps = 1/55 (1%)

Query: 24  EEEDEFYQTTYGGFTEESGDDEY-QGDQSDTEDEVDSDFDIDEGDEPSSDGEAEE 77
           EEE E      G   E  G++E  +G+  D E E + +    EG+E   +GE EE
Sbjct: 914 EEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEE 968



 Score = 28.5 bits (62), Expect = 9.9
 Identities = 25/135 (18%), Positives = 51/135 (37%), Gaps = 6/135 (4%)

Query: 6    GRAPRKTAGNRLSGLLEAEEEDEFYQTTYGGFTEESGDDEYQGDQSDTEDEVDSDFDIDE 65
            G    +  G    G  E EE +E      G   E+ G+ E      + E+E +  +  + 
Sbjct: 1019 GEVEGEVEGEEGEGEGEEEEGEE-----EGEEREKEGEGEENRRNREEEEEEEGKYQ-ET 1072

Query: 66   GDEPSSDGEAEEPRRKRRVVTKAYKEPLKSLRPRKVNTPAGSSQKAREEKALLPLELQDD 125
            G+E +   + EE ++  ++         K+ + + V    G+ ++ R +  +    L  +
Sbjct: 1073 GEEENERQDGEEYKKVSKIKGSVKYGKHKTYQKKSVTNTQGNGKEQRSKMPVQSKRLLKN 1132

Query: 126  GSDSRKSMRQSTAEH 140
            G    K    +   H
Sbjct: 1133 GPSGSKKFWNNVLPH 1147


>gi|15812186 F-box only protein 3 isoform 1 [Homo sapiens]
          Length = 471

 Score = 38.5 bits (88), Expect = 0.010
 Identities = 18/43 (41%), Positives = 25/43 (58%)

Query: 40  ESGDDEYQGDQSDTEDEVDSDFDIDEGDEPSSDGEAEEPRRKR 82
           E G DEY+  + + E+E + D D D  D   SD + EE RR+R
Sbjct: 414 EMGPDEYEEMEEEEEEEEEEDEDDDSADMDESDEDDEEERRRR 456


>gi|51093859 calcium channel, voltage-dependent, T type, alpha 1I
            subunit isoform b [Homo sapiens]
          Length = 2188

 Score = 38.5 bits (88), Expect = 0.010
 Identities = 61/250 (24%), Positives = 84/250 (33%), Gaps = 35/250 (14%)

Query: 106  GSSQKAREEKALLPLELQDDGSDSRKSMRQSTAEHTRQTFLRVQERQGQSRRRK-GPHCE 164
            GS    R  +    L  Q  GSD+      S++  + QT L        S RR  GP   
Sbjct: 1957 GSWASLRSPRVNCTLLRQATGSDTSLDASPSSSAGSLQTTLEDSLTLSDSPRRALGPPAP 2016

Query: 165  RPLTQEELLREAKITEELNLRSLETYERLEADKKKQVHKKRKCPGPIITYHSVTVPLVGE 224
             P  +  L   A+    L  R L +   L A ++   H       P  T+H         
Sbjct: 2017 APGPRAGLSPAARRRLSLRGRGLFSLRGLRAHQRS--HSSGGSTSPGCTHH--------- 2065

Query: 225  PGPKEENVDIEGLDPAPSVSALTPHAGTGPVNPPARCSRTFITFSDDATFEEWFPQGRPP 284
                      + +DP+          G G     +  S T  + S  + F    P   P 
Sbjct: 2066 ----------DSMDPSDEEG----RGGAGGGGAGSEHSETLSSLSLTSLFCPPPPPPAPG 2111

Query: 285  KVPVREVCPVTHRPALYRDPVTDIPYATARAFKIIRE---AYKKYITAHGLPPTASALGP 341
              P R+    +   A  R      P+A A A  + R    A  +     G  P    LGP
Sbjct: 2112 LTPARKFSSTSSLAAPGR------PHAAALAHGLARSPSWAADRSKDPPGRAPLPMGLGP 2165

Query: 342  GPPPPEPLPG 351
              PPP+PLPG
Sbjct: 2166 LAPPPQPLPG 2175


>gi|21361077 calcium channel, voltage-dependent, T type, alpha 1I
            subunit isoform a [Homo sapiens]
          Length = 2223

 Score = 38.5 bits (88), Expect = 0.010
 Identities = 61/250 (24%), Positives = 84/250 (33%), Gaps = 35/250 (14%)

Query: 106  GSSQKAREEKALLPLELQDDGSDSRKSMRQSTAEHTRQTFLRVQERQGQSRRRK-GPHCE 164
            GS    R  +    L  Q  GSD+      S++  + QT L        S RR  GP   
Sbjct: 1992 GSWASLRSPRVNCTLLRQATGSDTSLDASPSSSAGSLQTTLEDSLTLSDSPRRALGPPAP 2051

Query: 165  RPLTQEELLREAKITEELNLRSLETYERLEADKKKQVHKKRKCPGPIITYHSVTVPLVGE 224
             P  +  L   A+    L  R L +   L A ++   H       P  T+H         
Sbjct: 2052 APGPRAGLSPAARRRLSLRGRGLFSLRGLRAHQRS--HSSGGSTSPGCTHH--------- 2100

Query: 225  PGPKEENVDIEGLDPAPSVSALTPHAGTGPVNPPARCSRTFITFSDDATFEEWFPQGRPP 284
                      + +DP+          G G     +  S T  + S  + F    P   P 
Sbjct: 2101 ----------DSMDPSDEEG----RGGAGGGGAGSEHSETLSSLSLTSLFCPPPPPPAPG 2146

Query: 285  KVPVREVCPVTHRPALYRDPVTDIPYATARAFKIIRE---AYKKYITAHGLPPTASALGP 341
              P R+    +   A  R      P+A A A  + R    A  +     G  P    LGP
Sbjct: 2147 LTPARKFSSTSSLAAPGR------PHAAALAHGLARSPSWAADRSKDPPGRAPLPMGLGP 2200

Query: 342  GPPPPEPLPG 351
              PPP+PLPG
Sbjct: 2201 LAPPPQPLPG 2210


>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
           [Homo sapiens]
          Length = 918

 Score = 38.5 bits (88), Expect = 0.010
 Identities = 37/156 (23%), Positives = 71/156 (45%), Gaps = 6/156 (3%)

Query: 50  QSDTEDEVDSDF-DIDEGDEPSSDGEAEEPRRKRRVVTKAYKEPLKSLRPRKVNTPAGSS 108
           + + + +++  F  IDE  E + +    E + K++   K  +E     +  +        
Sbjct: 592 KEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWL 651

Query: 109 QKAREEKALLPLELQDDGSDSRKSMRQSTAEHTRQTFLRVQERQGQSRRRKGPHCERPLT 168
           Q+  EE+    L LQ    + ++ +R++ AE  R    R QER+ Q RR +    +    
Sbjct: 652 QQEEEERRHQEL-LQKKKEEEQERLRKA-AEAKRLAEQREQERREQERREQERREQERRE 709

Query: 169 QEELLREAKITEELNLRSLETYERLEADKKKQVHKK 204
           QE   +E ++ E+   R     ERL+A+++ Q  +K
Sbjct: 710 QERREQERQLAEQERRRE---QERLQAERELQEREK 742



 Score = 32.7 bits (73), Expect = 0.52
 Identities = 47/189 (24%), Positives = 77/189 (40%), Gaps = 32/189 (16%)

Query: 38  TEESGDDEYQGDQSDTEDEVDSDF-----------DIDEGDEPSSDGEAEEPRRKRR--- 83
           T  +G  E + DQ+D   E                ++DE ++   D E + PR K     
Sbjct: 424 TPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELDE-EQHLEDEELQPPRSKTPSSP 482

Query: 84  VVTKAYKEPLKSL-----RPRKVNTPAGSSQKAREE--KALLPLELQDDGSDSRKSMRQS 136
                   PL++      R + + TP  + +   +   K   PL +    S   K     
Sbjct: 483 CPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKCSFVEK----- 537

Query: 137 TAEHTRQTFLRVQERQGQSRRRKGPHCERPLTQE-ELLREAKITEELNLRSLETYERLEA 195
             E  R   LR +E   Q RR+K    +R   +E +L RE ++ + L  R  E  E+++ 
Sbjct: 538 --ERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQAR--ERVEQMKE 593

Query: 196 DKKKQVHKK 204
           +KKKQ+ +K
Sbjct: 594 EKKKQIEQK 602


>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
           [Homo sapiens]
          Length = 914

 Score = 38.5 bits (88), Expect = 0.010
 Identities = 37/156 (23%), Positives = 71/156 (45%), Gaps = 6/156 (3%)

Query: 50  QSDTEDEVDSDF-DIDEGDEPSSDGEAEEPRRKRRVVTKAYKEPLKSLRPRKVNTPAGSS 108
           + + + +++  F  IDE  E + +    E + K++   K  +E     +  +        
Sbjct: 588 KEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWL 647

Query: 109 QKAREEKALLPLELQDDGSDSRKSMRQSTAEHTRQTFLRVQERQGQSRRRKGPHCERPLT 168
           Q+  EE+    L LQ    + ++ +R++ AE  R    R QER+ Q RR +    +    
Sbjct: 648 QQEEEERRHQEL-LQKKKEEEQERLRKA-AEAKRLAEQREQERREQERREQERREQERRE 705

Query: 169 QEELLREAKITEELNLRSLETYERLEADKKKQVHKK 204
           QE   +E ++ E+   R     ERL+A+++ Q  +K
Sbjct: 706 QERREQERQLAEQERRRE---QERLQAERELQEREK 738



 Score = 34.7 bits (78), Expect = 0.14
 Identities = 41/172 (23%), Positives = 69/172 (40%), Gaps = 36/172 (20%)

Query: 65  EGDEPSSDGEAEEPRRKRRVVTKAYKEPLKSL--------------RPRKVNTPAGSSQK 110
           E     +DG  E P+  RR   ++YK+ +  L              R +  ++P  +S+ 
Sbjct: 431 EAKTDQADGPREPPQSARR--KRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKV 488

Query: 111 AREEKALL---------------PLELQDDGSDSRKSMRQSTAEHTRQTF--LRVQERQG 153
            R  +  L               P  +          +R    E  RQ    LR +E   
Sbjct: 489 VRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAE 548

Query: 154 QSRRRKGPHCERPLTQE-ELLREAKITEELNLRSLETYERLEADKKKQVHKK 204
           Q RR+K    +R   +E +L RE ++ + L  R  E  E+++ +KKKQ+ +K
Sbjct: 549 QLRRQKVEEDKRRRLEEVKLKREERLRKVLQAR--ERVEQMKEEKKKQIEQK 598


>gi|29244924 chromodomain helicase DNA binding protein 6 [Homo
           sapiens]
          Length = 2715

 Score = 38.1 bits (87), Expect = 0.012
 Identities = 36/135 (26%), Positives = 57/135 (42%), Gaps = 8/135 (5%)

Query: 77  EPRRKRRVVTKAYKEPLKSLRPRKVNTPAGSSQKAREEKALLPLELQDDGSDSRKSMRQS 136
           EP+ KR+   K  KEP K+  P+K        QK   +KA  P E    G+   K  R  
Sbjct: 115 EPKPKRKREPKEPKEPRKAKEPKKAKEHKEPKQKDGAKKARKPREA--SGTKEAKEKRSC 172

Query: 137 TAEHTRQTFLRVQERQGQS---RRRKGPHCERPLTQEELLREAKITEELNLRSLETYERL 193
           T    R    +  + QG +   +++KG   +   T E L  +  +T        E+ E  
Sbjct: 173 TDSAARTKSRKASKEQGPTPVEKKKKGKR-KSETTVESLELDQGLTNPSLRSPEESTEST 231

Query: 194 EADKKKQVH--KKRK 206
           ++ K++     K+RK
Sbjct: 232 DSQKRRSGRQVKRRK 246



 Score = 32.3 bits (72), Expect = 0.68
 Identities = 29/121 (23%), Positives = 49/121 (40%), Gaps = 9/121 (7%)

Query: 68  EPSSDGEAEEPRRKRRVVTKAYKEPLKSLRPRKVNTPAGSSQKAREEKALLPLELQDDGS 127
           EP     A +  + R    K  +EP +   PRK   P    +KA+E K       Q DG+
Sbjct: 100 EPGDQEGAAKGSKDREPKPKRKREPKEPKEPRKAKEP----KKAKEHKE----PKQKDGA 151

Query: 128 DSRKSMRQSTAEHTRQTFLRVQERQGQSRRRKGPHCERPLTQEELLREAKITEELNLRSL 187
              +  R+++     +      +   +++ RK    + P T  E  ++ K   E  + SL
Sbjct: 152 KKARKPREASGTKEAKEKRSCTDSAARTKSRKASKEQGP-TPVEKKKKGKRKSETTVESL 210

Query: 188 E 188
           E
Sbjct: 211 E 211


>gi|7019419 guanine nucleotide binding protein-like 2 (nucleolar)
           [Homo sapiens]
          Length = 731

 Score = 37.7 bits (86), Expect = 0.016
 Identities = 41/189 (21%), Positives = 74/189 (39%), Gaps = 28/189 (14%)

Query: 41  SGDDEYQGDQSDTEDEVDSDFD---------IDEGDEPSSDGEAEEPRRKRRVVTKAYKE 91
           SGDD    + SD E+E++S  D          D+ +E SS+ E E      + V KA  E
Sbjct: 543 SGDDLVPVEVSDLEEELESFSDEEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKALDE 602

Query: 92  PL----------KSLRPRKVNTPAGSSQ----KAREEKALLPLELQDDGSDSRKSMRQST 137
            +          K+ +   V    G S+    K  E++  L  ++ D     +   R++ 
Sbjct: 603 KIAKYQKFLDKAKAKKFSAVRISKGLSEKIFAKPEEQRKTLEEDVDDRAPSKKGKKRKAQ 662

Query: 138 AEHTRQTFLRVQERQGQSRRRKGPHCERPLTQEELLREAKITEELNLRSLETYERLEADK 197
            E  ++   +         RR+    +RP          +  E  N+++    ++   D 
Sbjct: 663 REEEQEHSNKAPRALTSKERRRAVRQQRPKKV-----GVRYYETHNVKNRNRNKKKTNDS 717

Query: 198 KKQVHKKRK 206
           + Q HK++K
Sbjct: 718 EGQKHKRKK 726


>gi|9994179 transcriptional regulator protein [Homo sapiens]
          Length = 308

 Score = 37.7 bits (86), Expect = 0.016
 Identities = 25/94 (26%), Positives = 51/94 (54%), Gaps = 7/94 (7%)

Query: 12  TAGNRLSGLL-EAEEEDEFYQTTYGGFTEESGDDEYQGDQSDTEDEVDSDFDIDEGDEPS 70
           +A     GL+ +A  ED+F  +  GG  +E G +E + + S   ++ DS+ +  E D+P 
Sbjct: 33  SAAEEKGGLVSDAYGEDDF--SRLGG--DEDGYEEEEDENSRQSEDDDSETEKPEADDPK 88

Query: 71  SDGEAEEPRRKRRVVTKAYKEPLKSLRPRKVNTP 104
            + EAE  +R  + +  ++ E ++++ P ++  P
Sbjct: 89  DNTEAE--KRDPQELVASFSERVRNMSPDEIKIP 120


>gi|93587342 voltage-gated sodium channel type 4 alpha [Homo
           sapiens]
          Length = 1836

 Score = 37.7 bits (86), Expect = 0.016
 Identities = 21/80 (26%), Positives = 38/80 (47%), Gaps = 7/80 (8%)

Query: 160 GPHCERPLTQEELLREAKITEELNLRSLETYERLEADKKKQVHKKRKCPGPIITYHSVTV 219
           GP C RP T+E L         +  R++E   RL+ +K+ ++ +  + P   +       
Sbjct: 13  GPECLRPFTRESL-------AAIEQRAVEEEARLQRNKQMEIEEPERKPRSDLEAGKNLP 65

Query: 220 PLVGEPGPKEENVDIEGLDP 239
            + G+P P+   + +E LDP
Sbjct: 66  MIYGDPPPEVIGIPLEDLDP 85


>gi|17975763 myelin transcription factor 1 [Homo sapiens]
          Length = 1121

 Score = 37.7 bits (86), Expect = 0.016
 Identities = 28/124 (22%), Positives = 52/124 (41%), Gaps = 11/124 (8%)

Query: 15  NRLSGLLEAEEEDEFYQTTYGGFTEESGDDEYQGDQSDTEDEVDSDFDIDEGDEPSSDGE 74
           ++  G+L  EEEDE          EE  ++E + +  + E+E + + + +E +E   + E
Sbjct: 249 SKQKGILSHEEEDE----------EEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEE 298

Query: 75  AEEPRRKRRVVTKAYKEPLKSLRPRKVNTPAG-SSQKAREEKALLPLELQDDGSDSRKSM 133
            EE   +       ++E       +K     G  S   + E +++     DD  D     
Sbjct: 299 EEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDEDTHS 358

Query: 134 RQST 137
           R+ST
Sbjct: 359 RKST 362


>gi|21237805 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin c2 isoform a [Homo sapiens]
          Length = 1214

 Score = 37.7 bits (86), Expect = 0.016
 Identities = 72/330 (21%), Positives = 120/330 (36%), Gaps = 35/330 (10%)

Query: 38   TEESGDDEYQGDQSDTEDEVDSDFDIDEGDEPSSDGEAEEPRRKRRVVTKAYKEPLKSLR 97
            +E    DE +G + D+E E +      +GD      + +EP+  +  V K   E     +
Sbjct: 791  SEAPKKDEEKGKEGDSEKESEKS----DGDPIVDPEKEKEPKEGQEEVLKEVVESEGERK 846

Query: 98   PR--------KVNTPAGSSQKAREEKALLPLELQDDGSDSRKSMRQSTAEHTRQTFLRVQ 149
             +         ++T A ++  A   KA     +++    S  ++   T     +  LR  
Sbjct: 847  TKVERDIGEGNLSTAAAAALAAAAVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHF 906

Query: 150  ERQGQSRRRKGPHCERPLTQEELLREAKITEELNLRSLETYERLEADKKKQVHKKRKCPG 209
            E       R+    E    Q    R+A   E+L    +    R      +Q+H++++ P 
Sbjct: 907  EELETIMDREREALEYQRQQLLADRQAFHMEQLKYAEM----RARQQHFQQMHQQQQQPP 962

Query: 210  PIITYHSVTVPLVGEPGPKEENVDIEGLDPAPSVSALTPHAGTGPVNPPARCSRTFITFS 269
            P +   S  +P  G  GP      + GL  AP+ S +   AG+G        S       
Sbjct: 963  PALPPGSQPIPPTGAAGPPA----VHGLAVAPA-SVVPAPAGSGAPPGSLGPSEQIGQAG 1017

Query: 270  DDATFEEWFPQG--RPPKVPVREVCPVTHRPALY---RDPVTDIPYATARAFKIIREAYK 324
              A  ++  P G  +P  VP     P  H P+ +   + P + +P A   +         
Sbjct: 1018 STAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGS--------- 1068

Query: 325  KYITAHGLPPTASALGPGPPPPEPLPGSGP 354
             +    G  P     G  PPPP P P   P
Sbjct: 1069 GHPGVAGNAPLGLPFGMPPPPPPPAPSIIP 1098


>gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo
           sapiens]
          Length = 1268

 Score = 37.4 bits (85), Expect = 0.021
 Identities = 44/168 (26%), Positives = 75/168 (44%), Gaps = 22/168 (13%)

Query: 40  ESGDDEYQGDQSDTEDEVDSDFDIDEGDEPSS----DGEAEEPRRKRRVVTKAYKEPLKS 95
           E  + EY+   S+ E+E +      +  EPSS     GE+   R   R+   A KE  ++
Sbjct: 315 EKDETEYEYSGSEEEEEEN------DSGEPSSILNLPGESTLRRDFLRLQL-ANKERSEA 367

Query: 96  LRPRKVNTPAGSSQKAREEKALLPLELQDDGSDSRKSMRQSTAEHTRQTFLRVQERQGQS 155
           LR +++       ++  E K  L  E Q    + ++  R+   +  R+  LR Q+ + Q 
Sbjct: 368 LRRQQLEQ---QQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQR 424

Query: 156 RRRKGPHCERPLTQEELLREAKITEELNLRSLETY---ERLEADKKKQ 200
           R     H E  + +EE  R A+  +E   + LE     ERL+   K++
Sbjct: 425 R-----HYEEQMRREEERRRAEHEQEYKRKQLEEQRQAERLQRQLKQE 467


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.132    0.386 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,214,375
Number of Sequences: 37866
Number of extensions: 1057371
Number of successful extensions: 9919
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 174
Number of HSP's successfully gapped in prelim test: 441
Number of HSP's that attempted gapping in prelim test: 7617
Number of HSP's gapped (non-prelim): 2222
length of query: 364
length of database: 18,247,518
effective HSP length: 104
effective length of query: 260
effective length of database: 14,309,454
effective search space: 3720458040
effective search space used: 3720458040
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press