Guide to the Human Genome
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Search of human proteins with 13378137

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|13378137 TNFRSF1A-associated via death domain [Homo sapiens]
         (312 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|13378137 TNFRSF1A-associated via death domain [Homo sapiens]       615   e-176
gi|57242761 receptor (TNFRSF)-interacting serine-threonine kinas...    45   8e-05
gi|6382071 diaphanous 2 isoform 12C [Homo sapiens]                     42   7e-04
gi|5803003 diaphanous 2 isoform 156 [Homo sapiens]                     42   7e-04
gi|223278403 glutamate receptor, ionotropic, delta 2 (Grid2) int...    39   0.008
gi|56549694 enabled homolog isoform a [Homo sapiens]                   39   0.008
gi|39930375 enabled homolog isoform b [Homo sapiens]                   39   0.008
gi|154448890 THO complex 1 [Homo sapiens]                              39   0.008
gi|49472841 A kinase (PRKA) anchor protein 8-like [Homo sapiens]       37   0.017
gi|32880208 diaphanous homolog 3 isoform b [Homo sapiens]              37   0.023
gi|110225351 diaphanous homolog 3 isoform a [Homo sapiens]             37   0.023
gi|55749531 splicing factor 3B subunit 2 [Homo sapiens]                37   0.023
gi|156071470 hyperpolarization activated cyclic nucleotide-gated...    37   0.029
gi|118766337 zinc finger protein of the cerebellum 5 [Homo sapiens]    37   0.029
gi|151301053 RNA binding motif protein 33 [Homo sapiens]               36   0.038
gi|23510413 sorting nexin 26 [Homo sapiens]                            36   0.038
gi|31543452 PX domain containing serine/threonine kinase [Homo s...    36   0.050
gi|116235472 SH3-domain GRB2-like (endophilin) interacting prote...    36   0.050
gi|5729962 submaxillary gland androgen regulated protein 3 homol...    35   0.066
gi|27734799 REST corepressor 2 [Homo sapiens]                          35   0.066
gi|153792074 proline rich 12 [Homo sapiens]                            35   0.066
gi|39812378 RAN binding protein 9 [Homo sapiens]                       35   0.086
gi|112789555 ADAM metallopeptidase with thrombospondin type 1 mo...    35   0.086
gi|157168329 formin 1 [Homo sapiens]                                   35   0.11 
gi|118572599 formin homology 2 domain containing 1 [Homo sapiens]      35   0.11 
gi|58331242 formin homology 2 domain containing 3 [Homo sapiens]       34   0.15 
gi|169167066 PREDICTED: hypothetical protein [Homo sapiens]            34   0.15 
gi|113416187 PREDICTED: hypothetical protein [Homo sapiens]            34   0.15 
gi|239745974 PREDICTED: hypothetical protein XP_002343630 [Homo ...    34   0.15 
gi|113415691 PREDICTED: hypothetical protein [Homo sapiens]            34   0.15 

>gi|13378137 TNFRSF1A-associated via death domain [Homo sapiens]
          Length = 312

 Score =  615 bits (1587), Expect = e-176
 Identities = 312/312 (100%), Positives = 312/312 (100%)

Query: 1   MAAGQNGHEEWVGSAYLFVESSLDKVVLSDAYAHPQQKVAVYRALQAALAESGGSPDVLQ 60
           MAAGQNGHEEWVGSAYLFVESSLDKVVLSDAYAHPQQKVAVYRALQAALAESGGSPDVLQ
Sbjct: 1   MAAGQNGHEEWVGSAYLFVESSLDKVVLSDAYAHPQQKVAVYRALQAALAESGGSPDVLQ 60

Query: 61  MLKIHRSDPQLIVQLRFCGRQPCGRFLRAYREGALRAALQRSLAAALAQHSVPLQLELRA 120
           MLKIHRSDPQLIVQLRFCGRQPCGRFLRAYREGALRAALQRSLAAALAQHSVPLQLELRA
Sbjct: 61  MLKIHRSDPQLIVQLRFCGRQPCGRFLRAYREGALRAALQRSLAAALAQHSVPLQLELRA 120

Query: 121 GAERLDALLADEERCLSCILAQQPDRLRDEELAELEDALRNLKCGSGARGGDGEVASAPL 180
           GAERLDALLADEERCLSCILAQQPDRLRDEELAELEDALRNLKCGSGARGGDGEVASAPL
Sbjct: 121 GAERLDALLADEERCLSCILAQQPDRLRDEELAELEDALRNLKCGSGARGGDGEVASAPL 180

Query: 181 QPPVPSLSEVKPPPPPPPAQTFLFQGQPVVNRPLSLKDQQTFARSVGLKWRKVGRSLQRG 240
           QPPVPSLSEVKPPPPPPPAQTFLFQGQPVVNRPLSLKDQQTFARSVGLKWRKVGRSLQRG
Sbjct: 181 QPPVPSLSEVKPPPPPPPAQTFLFQGQPVVNRPLSLKDQQTFARSVGLKWRKVGRSLQRG 240

Query: 241 CRALRDPALDSLAYEYEREGLYEQAFQLLRRFVQAEGRRATLQRLVEALEENELTSLAED 300
           CRALRDPALDSLAYEYEREGLYEQAFQLLRRFVQAEGRRATLQRLVEALEENELTSLAED
Sbjct: 241 CRALRDPALDSLAYEYEREGLYEQAFQLLRRFVQAEGRRATLQRLVEALEENELTSLAED 300

Query: 301 LLGLTDPNGGLA 312
           LLGLTDPNGGLA
Sbjct: 301 LLGLTDPNGGLA 312


>gi|57242761 receptor (TNFRSF)-interacting serine-threonine kinase 1
           [Homo sapiens]
          Length = 671

 Score = 45.1 bits (105), Expect = 8e-05
 Identities = 27/99 (27%), Positives = 50/99 (50%), Gaps = 8/99 (8%)

Query: 207 QPVVNRPLSLKDQQT--FARSVGLKWRKVGRSLQRGCRALRDPALDSLAYEYEREGLYEQ 264
           Q + +   SL D+       ++G  W+   R L           +D + ++YER+GL E+
Sbjct: 573 QAIFDNTTSLTDKHLDPIRENLGKHWKNCARKL-----GFTQSQIDEIDHDYERDGLKEK 627

Query: 265 AFQLLRRFVQAEG-RRATLQRLVEALEENELTSLAEDLL 302
            +Q+L+++V  EG + AT+ +L +AL +     L   L+
Sbjct: 628 VYQMLQKWVMREGIKGATVGKLAQALHQCSRIDLLSSLI 666


>gi|6382071 diaphanous 2 isoform 12C [Homo sapiens]
          Length = 1096

 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 35/146 (23%), Positives = 52/146 (35%), Gaps = 41/146 (28%)

Query: 141 AQQPDRLRDEELAELEDALRNLKCGSGARGGDGEVASAPLQPPVPSLSEVKPPP------ 194
           AQ   + RDE++ ELE  ++ L+  +        +   P  PP+P +    PPP      
Sbjct: 514 AQAELQKRDEKIKELEAEIQQLRTQAQVLSSSSGIPGPPAAPPLPGVGPPPPPPAPPLPG 573

Query: 195 -----------------PPPPAQTFLFQGQP--------------VVNRPLSLKDQQTFA 223
                            PPPP    LF G P               +N P  +K ++ + 
Sbjct: 574 GAPLPPPPPPLPGMMGIPPPPPPPLLFGGPPPPPPLGGVPPPPGISLNLPYGMKQKKMYK 633

Query: 224 RSVGLK---WRKV-GRSLQRGCRALR 245
             V +K   W K+    L   C  LR
Sbjct: 634 PEVSMKRINWSKIEPTELSENCFWLR 659


>gi|5803003 diaphanous 2 isoform 156 [Homo sapiens]
          Length = 1101

 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 35/146 (23%), Positives = 52/146 (35%), Gaps = 41/146 (28%)

Query: 141 AQQPDRLRDEELAELEDALRNLKCGSGARGGDGEVASAPLQPPVPSLSEVKPPP------ 194
           AQ   + RDE++ ELE  ++ L+  +        +   P  PP+P +    PPP      
Sbjct: 514 AQAELQKRDEKIKELEAEIQQLRTQAQVLSSSSGIPGPPAAPPLPGVGPPPPPPAPPLPG 573

Query: 195 -----------------PPPPAQTFLFQGQP--------------VVNRPLSLKDQQTFA 223
                            PPPP    LF G P               +N P  +K ++ + 
Sbjct: 574 GAPLPPPPPPLPGMMGIPPPPPPPLLFGGPPPPPPLGGVPPPPGISLNLPYGMKQKKMYK 633

Query: 224 RSVGLK---WRKV-GRSLQRGCRALR 245
             V +K   W K+    L   C  LR
Sbjct: 634 PEVSMKRINWSKIEPTELSENCFWLR 659


>gi|223278403 glutamate receptor, ionotropic, delta 2 (Grid2)
           interacting protein [Homo sapiens]
          Length = 1211

 Score = 38.5 bits (88), Expect = 0.008
 Identities = 26/81 (32%), Positives = 39/81 (48%), Gaps = 6/81 (7%)

Query: 157 DALRNLKCGSGARGGDGEVASAPLQPPVPSLSEVKPPPPPPPAQTFLFQGQPVVNRPLSL 216
           DA  + +   G+RG      +  L  P+  LS   PPPPPPP    +    P+++R L  
Sbjct: 766 DAKPSSRSSDGSRG-----PAQALAKPLTQLSHPVPPPPPPPLPPPVPCAPPMLSRGLGH 820

Query: 217 KDQQTFARSV-GLKWRKVGRS 236
           +  +T   SV  L+W +V  S
Sbjct: 821 RRSETSHMSVKRLRWEQVENS 841


>gi|56549694 enabled homolog isoform a [Homo sapiens]
          Length = 591

 Score = 38.5 bits (88), Expect = 0.008
 Identities = 25/62 (40%), Positives = 28/62 (45%), Gaps = 9/62 (14%)

Query: 179 PLQPPVPSLSEVKPPPPPP-----PAQTFLFQGQPVVNRPLSLKDQQTFARSVGLKWRKV 233
           P  PP P  ++V PPPPPP     PA  F        NRPL+       A   G K RKV
Sbjct: 349 PPPPPPPLPNQVPPPPPPPPAPPLPASGFFLASMSEDNRPLT----GLAAAIAGAKLRKV 404

Query: 234 GR 235
            R
Sbjct: 405 SR 406


>gi|39930375 enabled homolog isoform b [Homo sapiens]
          Length = 570

 Score = 38.5 bits (88), Expect = 0.008
 Identities = 25/62 (40%), Positives = 28/62 (45%), Gaps = 9/62 (14%)

Query: 179 PLQPPVPSLSEVKPPPPPP-----PAQTFLFQGQPVVNRPLSLKDQQTFARSVGLKWRKV 233
           P  PP P  ++V PPPPPP     PA  F        NRPL+       A   G K RKV
Sbjct: 349 PPPPPPPLPNQVPPPPPPPPAPPLPASGFFLASMSEDNRPLT----GLAAAIAGAKLRKV 404

Query: 234 GR 235
            R
Sbjct: 405 SR 406


>gi|154448890 THO complex 1 [Homo sapiens]
          Length = 657

 Score = 38.5 bits (88), Expect = 0.008
 Identities = 27/98 (27%), Positives = 48/98 (48%), Gaps = 7/98 (7%)

Query: 211 NRPLSLKDQQTFARSVGLKWRKVGRSLQRGCRALRDPALDSLAYEYEREGLYEQAFQLLR 270
           ++P++ +  + FA  +G +W+ +   L+     +R    DS       E +  +A QLL 
Sbjct: 566 DKPVTGEQIEVFANKLGEQWKILAPYLEMKDSEIRQIECDS-------EDMKMRAKQLLV 618

Query: 271 RFVQAEGRRATLQRLVEALEENELTSLAEDLLGLTDPN 308
            +   EG  AT + L+ AL ++ L+ LAE L    + N
Sbjct: 619 AWQDQEGVHATPENLINALNKSGLSDLAESLTNDNETN 656


>gi|49472841 A kinase (PRKA) anchor protein 8-like [Homo sapiens]
          Length = 646

 Score = 37.4 bits (85), Expect = 0.017
 Identities = 21/60 (35%), Positives = 33/60 (55%), Gaps = 5/60 (8%)

Query: 144 PDRLRDEELAE---LEDALRNLKCGSGARGGDGEVASAPLQPPVPSLSEVKPPPPPPPAQ 200
           P+  +++E AE   L++  +    G  + G +G  A  P+ PP P+   V PPPPPPP +
Sbjct: 553 PEEEKEQEEAEGGALDEGAQGEAAGI-SEGAEGVPAQPPV-PPEPAPGAVSPPPPPPPEE 610


>gi|32880208 diaphanous homolog 3 isoform b [Homo sapiens]
          Length = 849

 Score = 37.0 bits (84), Expect = 0.023
 Identities = 18/38 (47%), Positives = 20/38 (52%), Gaps = 1/38 (2%)

Query: 161 NLKCGSGARGGDGEVASAPLQPPVPSLSEVKPPPPPPP 198
           N+       GG G  A  P  PP+PS   V PPPPPPP
Sbjct: 296 NIPLPPSKEGGTGHSALPP-PPPLPSGGGVPPPPPPPP 332


>gi|110225351 diaphanous homolog 3 isoform a [Homo sapiens]
          Length = 1193

 Score = 37.0 bits (84), Expect = 0.023
 Identities = 18/38 (47%), Positives = 20/38 (52%), Gaps = 1/38 (2%)

Query: 161 NLKCGSGARGGDGEVASAPLQPPVPSLSEVKPPPPPPP 198
           N+       GG G  A  P  PP+PS   V PPPPPPP
Sbjct: 559 NIPLPPSKEGGTGHSALPP-PPPLPSGGGVPPPPPPPP 595


>gi|55749531 splicing factor 3B subunit 2 [Homo sapiens]
          Length = 895

 Score = 37.0 bits (84), Expect = 0.023
 Identities = 20/55 (36%), Positives = 27/55 (49%), Gaps = 10/55 (18%)

Query: 169 RGGDGEVASAP----------LQPPVPSLSEVKPPPPPPPAQTFLFQGQPVVNRP 213
           RG DG+ A+ P          + PP   L  ++PPPPPPP    L  G P+ + P
Sbjct: 71  RGEDGDKAAPPPMSAQLPGIPMPPPPLGLPPLQPPPPPPPPPPGLGLGFPMAHPP 125


>gi|156071470 hyperpolarization activated cyclic nucleotide-gated
           potassium channel 2 [Homo sapiens]
          Length = 889

 Score = 36.6 bits (83), Expect = 0.029
 Identities = 17/38 (44%), Positives = 22/38 (57%), Gaps = 3/38 (7%)

Query: 165 GSGARGGDGEVAS---APLQPPVPSLSEVKPPPPPPPA 199
           G G R G+   A+    P  PP P+  + +PPPPPPPA
Sbjct: 5   GGGGRPGESPGATPAPGPPPPPPPAPPQQQPPPPPPPA 42


>gi|118766337 zinc finger protein of the cerebellum 5 [Homo sapiens]
          Length = 663

 Score = 36.6 bits (83), Expect = 0.029
 Identities = 15/35 (42%), Positives = 17/35 (48%)

Query: 164 CGSGARGGDGEVASAPLQPPVPSLSEVKPPPPPPP 198
           CG G+ G        P  P  P+ S   PPPPPPP
Sbjct: 138 CGGGSSGAQPSAPPPPAPPLPPTPSPPPPPPPPPP 172



 Score = 30.4 bits (67), Expect = 2.1
 Identities = 14/26 (53%), Positives = 15/26 (57%), Gaps = 5/26 (19%)

Query: 174 EVASAPLQPPVPSLSEVKPPPPPPPA 199
           E+A  P  PP P      PPPPPPPA
Sbjct: 405 ELAGLPPPPPPPP-----PPPPPPPA 425


>gi|151301053 RNA binding motif protein 33 [Homo sapiens]
          Length = 1170

 Score = 36.2 bits (82), Expect = 0.038
 Identities = 20/41 (48%), Positives = 23/41 (56%), Gaps = 5/41 (12%)

Query: 172 DGEVASAPLQPPVPSLSEVKPPPPPPPAQ---TFLFQGQPV 209
           D   A  P QPPV  + +  PPPPPPP Q     LFQ QP+
Sbjct: 303 DHRPALLPTQPPV--VPQAPPPPPPPPQQQPIRSLFQPQPL 341



 Score = 28.9 bits (63), Expect = 6.1
 Identities = 14/31 (45%), Positives = 16/31 (51%), Gaps = 2/31 (6%)

Query: 181 QPPVPS--LSEVKPPPPPPPAQTFLFQGQPV 209
           +P  PS    E + PPPPPP  T L    PV
Sbjct: 468 EPRFPSHLFLEQRSPPPPPPPPTLLNSSHPV 498


>gi|23510413 sorting nexin 26 [Homo sapiens]
          Length = 1126

 Score = 36.2 bits (82), Expect = 0.038
 Identities = 27/80 (33%), Positives = 34/80 (42%), Gaps = 3/80 (3%)

Query: 144 PDRLRDEELAELEDALRNLKCGS--GARGGDGEVASAPLQPPVPSLSEVKPPPPPPPAQT 201
           P  LR  E A L DA +   C    GA+G  G    +PL PP  SL      PPPPP   
Sbjct: 677 PLLLRGAE-APLTDACQQEMCSKLRGAQGPLGPDMESPLPPPPLSLLRPGGAPPPPPKNP 735

Query: 202 FLFQGQPVVNRPLSLKDQQT 221
                  +  R   + +QQ+
Sbjct: 736 ARLMALALAERAQQVAEQQS 755


>gi|31543452 PX domain containing serine/threonine kinase [Homo
           sapiens]
          Length = 578

 Score = 35.8 bits (81), Expect = 0.050
 Identities = 22/71 (30%), Positives = 33/71 (46%), Gaps = 2/71 (2%)

Query: 130 ADEERCLSCILAQQPDRLRDEELAELEDALRNLKCGSGARGGDGEVAS--APLQPPVPSL 187
           ++EER    ILA++  +    E +E   A  +    S   G    + S  +P  P    +
Sbjct: 452 SEEERKKRKILARKKSKRSALENSEEHSAKYSNSNNSAGSGASSPLTSPSSPTPPSTSGI 511

Query: 188 SEVKPPPPPPP 198
           S + PPPPPPP
Sbjct: 512 SALPPPPPPPP 522


>gi|116235472 SH3-domain GRB2-like (endophilin) interacting protein
           1 [Homo sapiens]
          Length = 828

 Score = 35.8 bits (81), Expect = 0.050
 Identities = 25/58 (43%), Positives = 31/58 (53%), Gaps = 7/58 (12%)

Query: 165 GSGARGGDGEVASAPLQPP---VPSLSEVKPPPPP-PPAQTFLFQGQP---VVNRPLS 215
           GSG   G    AS+P +P    VP  S   PPPPP PP++  L  G+P    V+RP S
Sbjct: 429 GSGPGPGTTSGASSPARPATPLVPCRSTTPPPPPPRPPSRPKLPPGKPGVGDVSRPFS 486


>gi|5729962 submaxillary gland androgen regulated protein 3 homolog
           B [Homo sapiens]
          Length = 79

 Score = 35.4 bits (80), Expect = 0.066
 Identities = 16/34 (47%), Positives = 16/34 (47%)

Query: 165 GSGARGGDGEVASAPLQPPVPSLSEVKPPPPPPP 198
           G   RG  G     PL PP P      PPPPPPP
Sbjct: 20  GESQRGPRGPYPPGPLAPPQPFGPGFVPPPPPPP 53


>gi|27734799 REST corepressor 2 [Homo sapiens]
          Length = 523

 Score = 35.4 bits (80), Expect = 0.066
 Identities = 22/60 (36%), Positives = 28/60 (46%), Gaps = 2/60 (3%)

Query: 155 LEDALRNLKCGSGARGGDGEVASAPLQPPVPSLSEVKPPPPPPPAQTFLFQGQPVVNRPL 214
           +E+A R     + A   D EV    +   VP      PPPPPPP  T L Q  P++  PL
Sbjct: 400 MEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAPPPPPPP--TSLSQPPPLLRPPL 457


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 35.4 bits (80), Expect = 0.066
 Identities = 37/122 (30%), Positives = 45/122 (36%), Gaps = 13/122 (10%)

Query: 93   GALRAALQRSLAAALAQHSVPLQLELRAGAERLDALLADEE------RCLSCILAQQPDR 146
            GAL AA    L          L  EL+   E L +  +DEE      R L   ++     
Sbjct: 1345 GALEAAESEGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISA 1404

Query: 147  LRDEELAELEDA-------LRNLKCGSGARGGDGEVASAPLQPPVPSLSEVKPPPPPPPA 199
            L D  LA  +D        L       G     G  ++     P P L E KPPP PPPA
Sbjct: 1405 LDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPA 1464

Query: 200  QT 201
             T
Sbjct: 1465 PT 1466



 Score = 33.1 bits (74), Expect = 0.33
 Identities = 15/32 (46%), Positives = 19/32 (59%), Gaps = 1/32 (3%)

Query: 179  PLQPPVPSLSEVKPPPPPPPAQTFLFQGQPVV 210
            P  PP P+  + +PPPPPPP Q  L    P+V
Sbjct: 1459 PTPPPAPT-PQPQPPPPPPPPQPALPSPPPLV 1489



 Score = 30.8 bits (68), Expect = 1.6
 Identities = 19/51 (37%), Positives = 22/51 (43%), Gaps = 5/51 (9%)

Query: 175  VASAPLQPPVPSLSEVKPPPPPPPAQTFLFQGQPVVNRPLSLKDQQTFARS 225
            VA  P  PP P L     PPPPPPA        P    PL+   ++  A S
Sbjct: 1489 VAPTPSSPPPPPL-----PPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPS 1534



 Score = 30.8 bits (68), Expect = 1.6
 Identities = 26/80 (32%), Positives = 30/80 (37%), Gaps = 12/80 (15%)

Query: 179  PLQPPVPSLSEVKPPPPPPPAQTFLF--QGQPVV----------NRPLSLKDQQTFARSV 226
            P  PP P  +   PPPPPPPA   L     +P             RPL L  +Q  A   
Sbjct: 1499 PPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQETAAVC 1558

Query: 227  GLKWRKVGRSLQRGCRALRD 246
            G    + G S   G    RD
Sbjct: 1559 GETDEEAGESGGEGIFRERD 1578


>gi|39812378 RAN binding protein 9 [Homo sapiens]
          Length = 729

 Score = 35.0 bits (79), Expect = 0.086
 Identities = 17/38 (44%), Positives = 21/38 (55%), Gaps = 6/38 (15%)

Query: 167 GARGGDGEVASA------PLQPPVPSLSEVKPPPPPPP 198
           G  GG+G  A+A      P  PP P+ +   PPPPPPP
Sbjct: 53  GGAGGEGLGAAAAALLLHPPPPPPPATAAPPPPPPPPP 90



 Score = 32.0 bits (71), Expect = 0.72
 Identities = 14/34 (41%), Positives = 16/34 (47%)

Query: 165 GSGARGGDGEVASAPLQPPVPSLSEVKPPPPPPP 198
           G+G  G     A+  L PP P       PPPPPP
Sbjct: 54  GAGGEGLGAAAAALLLHPPPPPPPATAAPPPPPP 87


>gi|112789555 ADAM metallopeptidase with thrombospondin type 1
           motif, 19 preproprotein [Homo sapiens]
          Length = 1207

 Score = 35.0 bits (79), Expect = 0.086
 Identities = 33/94 (35%), Positives = 39/94 (41%), Gaps = 12/94 (12%)

Query: 144 PDRLRDEELAELEDALRNLKCGSGARGGDGEVASAPLQPPVPSLSEVKPPPPPPPAQTFL 203
           P     EE  ELE   + L  GS         A A  QPP P     +PPP PPPAQ   
Sbjct: 106 PPPSEGEEDEELES--QELPRGSSGAAALSPGAPASWQPPPPP----QPPPSPPPAQHAE 159

Query: 204 FQGQPVVNRPLSLKDQQTFARSVGLKWRKVGRSL 237
             G  V+ R         F+R + L  R+ GR L
Sbjct: 160 PDGDEVLLR------IPAFSRDLYLLLRRDGRFL 187


>gi|157168329 formin 1 [Homo sapiens]
          Length = 1196

 Score = 34.7 bits (78), Expect = 0.11
 Identities = 14/28 (50%), Positives = 18/28 (64%)

Query: 171 GDGEVASAPLQPPVPSLSEVKPPPPPPP 198
           G G ++ AP  PPV +   + PPPPPPP
Sbjct: 661 GLGSLSPAPPMPPVSAGPPLPPPPPPPP 688



 Score = 32.3 bits (72), Expect = 0.55
 Identities = 12/20 (60%), Positives = 13/20 (65%)

Query: 179 PLQPPVPSLSEVKPPPPPPP 198
           P  PP+P  S   PPPPPPP
Sbjct: 685 PPPPPLPPPSSAGPPPPPPP 704


>gi|118572599 formin homology 2 domain containing 1 [Homo sapiens]
          Length = 1164

 Score = 34.7 bits (78), Expect = 0.11
 Identities = 43/140 (30%), Positives = 64/140 (45%), Gaps = 20/140 (14%)

Query: 173 GEVASAPLQPPVPSLSEVKPPP--PPPPAQTFLFQGQP----VVNRPLSLKDQQ---TFA 223
           G+   AP  PP+P LS V PPP  PPPP     F   P        P S+ D     T  
Sbjct: 566 GKDIPAP-SPPLPLLSGVPPPPPLPPPPPIKGPFPPPPPLPLAAPLPHSVPDSSALPTKR 624

Query: 224 RSVGLKWRKVGRSLQRGCRALRD-------PALDSLAYEYER-EGLYE-QAFQLLRRFVQ 274
           ++V L WR++  +   G  A R         +LD ++ +  R E L+E +A ++L     
Sbjct: 625 KTVKLFWRELKLAGGHGVSASRFGPCATLWASLDPVSVDTARLEHLFESRAKEVLPSKKA 684

Query: 275 AEGRRATLQRLVEALEENEL 294
            EGRR T+  +++    N +
Sbjct: 685 GEGRR-TMTTVLDPKRSNAI 703


>gi|58331242 formin homology 2 domain containing 3 [Homo sapiens]
          Length = 1439

 Score = 34.3 bits (77), Expect = 0.15
 Identities = 28/92 (30%), Positives = 38/92 (41%), Gaps = 10/92 (10%)

Query: 146 RLRDEELAEL--EDALRNLKCGSGARGGDGEVASAPLQPPVPSLSEVKPPPPPPPAQTFL 203
           R++D +  +L  ED +  L    G R   G     P  PP P+   + PPPPPP   +  
Sbjct: 816 RIQDMDFTDLGEEDDIDVLDVDLGHREAPG-----PPPPPPPTFLGLPPPPPPPLLDSI- 869

Query: 204 FQGQPVVNRPLSLKDQQTFARSVGLKWRKVGR 235
               P V   L +     F    GL W +V R
Sbjct: 870 --PPPPVPGNLLVPPPPVFNAPQGLGWSQVPR 899


>gi|169167066 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 262

 Score = 34.3 bits (77), Expect = 0.15
 Identities = 18/39 (46%), Positives = 21/39 (53%), Gaps = 7/39 (17%)

Query: 167 GARGGDGEVASAPL--QPP-----VPSLSEVKPPPPPPP 198
           G  GG+G  A  P+  QPP     VP  +   PPPPPPP
Sbjct: 2   GKAGGEGGEAGPPMSAQPPSSADTVPGTTYPPPPPPPPP 40


>gi|113416187 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 262

 Score = 34.3 bits (77), Expect = 0.15
 Identities = 18/39 (46%), Positives = 21/39 (53%), Gaps = 7/39 (17%)

Query: 167 GARGGDGEVASAPL--QPP-----VPSLSEVKPPPPPPP 198
           G  GG+G  A  P+  QPP     VP  +   PPPPPPP
Sbjct: 2   GKAGGEGGEAGPPMSAQPPSSADTVPGTTYPPPPPPPPP 40


>gi|239745974 PREDICTED: hypothetical protein XP_002343630 [Homo
           sapiens]
          Length = 538

 Score = 34.3 bits (77), Expect = 0.15
 Identities = 28/82 (34%), Positives = 36/82 (43%), Gaps = 7/82 (8%)

Query: 165 GSGARGGDGEVASAPLQPPV----PSLSEVKPPPPPPPAQTFLFQGQPVVNRPLSLKDQQ 220
           G G R G G  ++ P  PP+    P     +PPPPPPP    L    P   R L  K+  
Sbjct: 204 GPGPRRGGGLTSAPPGLPPLASPPPFWELPRPPPPPPPPGPALL---PRRLRELRGKEVG 260

Query: 221 TFARSVGLKWRKVGRSLQRGCR 242
              R+ G     V  +L+RG R
Sbjct: 261 LRPRTRGWTTCVVSPNLRRGSR 282


>gi|113415691 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 262

 Score = 34.3 bits (77), Expect = 0.15
 Identities = 18/39 (46%), Positives = 21/39 (53%), Gaps = 7/39 (17%)

Query: 167 GARGGDGEVASAPL--QPP-----VPSLSEVKPPPPPPP 198
           G  GG+G  A  P+  QPP     VP  +   PPPPPPP
Sbjct: 2   GKAGGEGGEAGPPMSAQPPSSADTVPGTTYPPPPPPPPP 40


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.135    0.391 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,253,330
Number of Sequences: 37866
Number of extensions: 698867
Number of successful extensions: 11324
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 173
Number of HSP's successfully gapped in prelim test: 190
Number of HSP's that attempted gapping in prelim test: 7957
Number of HSP's gapped (non-prelim): 2449
length of query: 312
length of database: 18,247,518
effective HSP length: 102
effective length of query: 210
effective length of database: 14,385,186
effective search space: 3020889060
effective search space used: 3020889060
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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