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Search of human proteins with 5174595
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5174595 melatonin receptor 1B [Homo sapiens]
(362 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5174595 melatonin receptor 1B [Homo sapiens] 739 0.0
gi|5174593 melatonin receptor 1A [Homo sapiens] 421 e-118
gi|150170722 G protein-coupled receptor 50 [Homo sapiens] 331 5e-91
gi|4505445 neuropeptide Y receptor Y1 [Homo sapiens] 127 2e-29
gi|4557857 somatostatin receptor 1 [Homo sapiens] 119 6e-27
gi|11545887 neuropeptide FF receptor 1 [Homo sapiens] 118 7e-27
gi|157738685 G protein-coupled receptor 103 [Homo sapiens] 118 9e-27
gi|4557865 somatostatin receptor 5 [Homo sapiens] 117 1e-26
gi|4758474 G protein-coupled receptor 10 [Homo sapiens] 117 2e-26
gi|167000885 galanin receptor 1 [Homo sapiens] 116 4e-26
gi|4507343 tachykinin receptor 1 isoform long [Homo sapiens] 115 5e-26
gi|149944554 somatostatin receptor 4 [Homo sapiens] 115 8e-26
gi|157364957 pancreatic polypeptide receptor 1 [Homo sapiens] 113 2e-25
gi|4557859 somatostatin receptor 2 [Homo sapiens] 112 4e-25
gi|7669546 tachykinin receptor 1 isoform short [Homo sapiens] 110 3e-24
gi|223633971 G protein-coupled receptor 83 [Homo sapiens] 108 1e-23
gi|223718055 opioid receptor, mu 1 isoform MOR-1H [Homo sapiens] 107 2e-23
gi|117940060 opioid receptor, mu 1 isoform MOR-1 [Homo sapiens] 107 2e-23
gi|223718712 opioid receptor, mu 1 isoform MOR-1B5 [Homo sapiens] 107 2e-23
gi|223718719 opioid receptor, mu 1 isoform MOR-1B2 [Homo sapiens] 107 2e-23
gi|223718077 opioid receptor, mu 1 isoform MOR-1B3 [Homo sapiens] 107 2e-23
gi|223718716 opioid receptor, mu 1 isoform MOR-1B1 [Homo sapiens] 107 2e-23
gi|15150803 opsin 4 isoform 1 [Homo sapiens] 107 2e-23
gi|117940058 opioid receptor, mu 1 isoform MOR-1A [Homo sapiens] 107 2e-23
gi|223717969 opioid receptor, mu 1 isoform MOR-1B4 [Homo sapiens] 107 2e-23
gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens] 107 2e-23
gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens] 107 2e-23
gi|117940055 opioid receptor, mu 1 isoform MOR-1O [Homo sapiens] 107 2e-23
gi|117940054 opioid receptor, mu 1 isoform MOR-1X [Homo sapiens] 107 2e-23
gi|4557861 somatostatin receptor 3 [Homo sapiens] 106 3e-23
>gi|5174595 melatonin receptor 1B [Homo sapiens]
Length = 362
Score = 739 bits (1908), Expect = 0.0
Identities = 362/362 (100%), Positives = 362/362 (100%)
Query: 1 MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLL 60
MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLL
Sbjct: 1 MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLL 60
Query: 61 VILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVM 120
VILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVM
Sbjct: 61 VILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVM 120
Query: 121 GLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGS 180
GLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGS
Sbjct: 121 GLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGS 180
Query: 181 LEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRL 240
LEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRL
Sbjct: 181 LEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRL 240
Query: 241 CLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFN 300
CLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFN
Sbjct: 241 CLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFN 300
Query: 301 SCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQAD 360
SCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQAD
Sbjct: 301 SCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQAD 360
Query: 361 AL 362
AL
Sbjct: 361 AL 362
>gi|5174593 melatonin receptor 1A [Homo sapiens]
Length = 350
Score = 421 bits (1083), Expect = e-118
Identities = 205/335 (61%), Positives = 257/335 (76%), Gaps = 8/335 (2%)
Query: 24 GAGSARPSRTP--------RPPWVAPALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAG 75
G GSA P+ + RP W+A AL+ VLI T VD++GNLLVILSV RN+KLRNAG
Sbjct: 3 GNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRNAG 62
Query: 76 NLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIA 135
N+F+VSLA+ADLVVA YPYPL+L++IF +GW LG HC+ S F+MGLSVIGS+FNIT IA
Sbjct: 63 NIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIA 122
Query: 136 INRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGSLEYDPRIYSCTFIQT 195
INRYCYICHS+ Y ++Y ++ ++ LIWLLT+ A+LPN G+L+YDPRIYSCTF Q+
Sbjct: 123 INRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQS 182
Query: 196 ASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRLCLKPSDLRSFLTMFV 255
S+ YT AVVV HFL+P+ +V FCYLRIW+LVLQ R++ KP+ + LKP D R+F+TMFV
Sbjct: 183 VSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTMFV 242
Query: 256 VFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFNSCLNAIVYGLLNQNF 315
VFV+FAICWAPLN IGLAVA +P M P+IPE LFV SY +AYFNSCLNAI+YGLLNQNF
Sbjct: 243 VFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNF 302
Query: 316 RREYKRILLALWNPRHCIQDASKGSHAEGLQSPAP 350
R+EY+RI+++L R D+S P+P
Sbjct: 303 RKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSP 337
>gi|150170722 G protein-coupled receptor 50 [Homo sapiens]
Length = 617
Score = 331 bits (849), Expect = 5e-91
Identities = 148/296 (50%), Positives = 223/296 (75%), Gaps = 6/296 (2%)
Query: 36 PPWVAPALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYP 95
PP + + +++T VD++GN +VIL+V +N+KLRN+GN+F+VSL++AD++VA YPYP
Sbjct: 24 PPALIIFMFCAMVITIVVDLIGNSMVILAVTKNKKLRNSGNIFVVSLSVADMLVAIYPYP 83
Query: 96 LILVAIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRW 155
L+L A+ GW L + C+ F+ GLSV+GS+FNI AIAINRYCYICHS+ Y RI+
Sbjct: 84 LMLHAMSIGGWDLSQLQCQMVGFITGLSVVGSIFNIVAIAINRYCYICHSLQYERIFSVR 143
Query: 156 HTPLHICLIWLLTVVALLPNFFVGSLEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAV 215
+T +++ + W++TV+A+LPN ++G++EYDPR Y+C F + +T +V IHF+LP+ +
Sbjct: 144 NTCIYLVITWIMTVLAVLPNMYIGTIEYDPRTYTCIFNYLNNPVFTVTIVCIHFVLPLLI 203
Query: 216 VSFCYLRIWVLVLQARRKA--KPESRLCLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLA 273
V FCY+RIW VL AR A P+++L +++R+FLTMFV+F++FA+CW P+N + +
Sbjct: 204 VGFCYVRIWTKVLAARDPAGQNPDNQL----AEVRNFLTMFVIFLLFAVCWCPINVLTVL 259
Query: 274 VAINPQEMAPQIPEGLFVTSYLLAYFNSCLNAIVYGLLNQNFRREYKRILLALWNP 329
VA++P+EMA +IP L++ +Y +AYFNSCLNA++YGLLN+NFRREY I A+ +P
Sbjct: 260 VAVSPKEMAGKIPNWLYLAAYFIAYFNSCLNAVIYGLLNENFRREYWTIFHAMRHP 315
>gi|4505445 neuropeptide Y receptor Y1 [Homo sapiens]
Length = 384
Score = 127 bits (319), Expect = 2e-29
Identities = 85/295 (28%), Positives = 144/295 (48%), Gaps = 22/295 (7%)
Query: 39 VAPALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLIL 98
+A A AV+I+ V GNL +I+ +L+ +++RN N+ +V+L+ +DL+VA P
Sbjct: 43 LALAYGAVIIL----GVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTF 98
Query: 99 VAIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTP 158
V D W GE CK + FV +S+ S+F++ IA+ R+ I + + R H
Sbjct: 99 VYTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNR--HAY 156
Query: 159 LHICLIWLLTVVALLPNFFVGSLEYDPRIYSCT----------FIQTAS----TQYTAAV 204
+ I +IW+L V + LP F + + D + T F Q S YT +
Sbjct: 157 VGIAVIWVLAVASSLP-FLIYQVMTDEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLL 215
Query: 205 VVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRLCLKPSDLRSFLTMFV-VFVIFAIC 263
+V+ + P+ + CY +I++ + + + S+ + M + + V FA+C
Sbjct: 216 LVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVC 275
Query: 264 WAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFNSCLNAIVYGLLNQNFRRE 318
W PL N Q +A LF+ +L A ++C+N I YG LN+NF+R+
Sbjct: 276 WLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRD 330
>gi|4557857 somatostatin receptor 1 [Homo sapiens]
Length = 391
Score = 119 bits (297), Expect = 6e-27
Identities = 89/332 (26%), Positives = 153/332 (46%), Gaps = 25/332 (7%)
Query: 11 CEAGGWAVRPGWSGA-GSARPSRTPRPPWV-------APALSAVLIVTTAVDVVGNLLVI 62
C GG + PG A G P R A +S + V V + GN +VI
Sbjct: 21 CGEGGGSRGPGAGAADGMEEPGRNASQNGTLSEGQGSAILISFIYSVVCLVGLCGNSMVI 80
Query: 63 LSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVMGL 122
+LR K++ A N+++++LA+AD ++ P ++ + W G C+ V +
Sbjct: 81 YVILRYAKMKTATNIYILNLAIADELLML-SVPFLVTSTLLRHWPFGALLCRLVLSVDAV 139
Query: 123 SVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICL-IWLLTVVALLPNF-FVGS 180
++ S++ +T ++++RY + H + R YRR + L +W+L+++ +LP F +
Sbjct: 140 NMFTSIYCLTVLSVDRYVAVVHPIKAAR-YRRPTVAKVVNLGVWVLSLLVILPIVVFSRT 198
Query: 181 LEYDPRIYSCTFIQTASTQYTAAVVVIH-----FLLPIAVVSFCYLRIWVLVLQARRKAK 235
+C + Q V++ FLLP+ + CY+ I + KA
Sbjct: 199 AANSDGTVACNMLMPEPAQRWLVGFVLYTFLMGFLLPVGAICLCYVLIIAKMRMVALKAG 258
Query: 236 PESRLCLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYL 295
+ R K S+ + L + +V ++F ICW P + L Q+ A + S +
Sbjct: 259 WQQR---KRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFAEQDDAT-----VSQLSVI 310
Query: 296 LAYFNSCLNAIVYGLLNQNFRREYKRILLALW 327
L Y NSC N I+YG L+ NF+R ++RIL W
Sbjct: 311 LGYANSCANPILYGFLSDNFKRSFQRILCLSW 342
>gi|11545887 neuropeptide FF receptor 1 [Homo sapiens]
Length = 430
Score = 118 bits (296), Expect = 7e-27
Identities = 94/312 (30%), Positives = 143/312 (45%), Gaps = 34/312 (10%)
Query: 55 VVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCK 114
+VGN LV VL+NR + N+F+++LA++DL+V + P LV GW CK
Sbjct: 58 MVGNTLVCFIVLKNRHMHTVTNMFILNLAVSDLLVGIFCMPTTLVDNLITGWPFDNATCK 117
Query: 115 ASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLP 174
S V G+SV SVF + AIA+ R+ I H R+ + I +IW L ++ + P
Sbjct: 118 MSGLVQGMSVSASVFTLVAIAVERFRCIVHPFREKLTLRK--ALVTIAVIWALALLIMCP 175
Query: 175 ------------NFFVGSLEYDPRIYSC--TFIQTASTQYTAAVVVIH-FLLPIAVVSFC 219
+F V + +YSC + + + V+ H +L P+A++
Sbjct: 176 SAVTLTVTREEHHFMVDARNRSYPLYSCWEAWPEKGMRRVYTTVLFSHIYLAPLALIVVM 235
Query: 220 YLRIWVLVLQARRKA-----KPESRLCLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAV 274
Y RI + QA A + R + + + L M +F F + W PL + L +
Sbjct: 236 YARIARKLCQAPGPAPGGEEAADPRASRRRARVVHMLVMVALF--FTLSWLPLWALLLLI 293
Query: 275 AINPQEMAPQ---IPEGLFVTSYLLAYFNSCLNAIVYGLLNQNFRREYKRILLALWNPRH 331
Q APQ + F ++ LA+FNS N I+YG N+NFRR ++ A PR
Sbjct: 294 DYG-QLSAPQLHLVTVYAFPFAHWLAFFNSSANPIIYGYFNENFRRGFQAAFRARLCPR- 351
Query: 332 CIQDASKGSHAE 343
GSH E
Sbjct: 352 -----PSGSHKE 358
>gi|157738685 G protein-coupled receptor 103 [Homo sapiens]
Length = 431
Score = 118 bits (295), Expect = 9e-27
Identities = 86/302 (28%), Positives = 144/302 (47%), Gaps = 29/302 (9%)
Query: 39 VAPALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLIL 98
+A L+ VLI A+ GN LV V R++ +R N+F+ SLAL+DL++ F+ P+ +
Sbjct: 46 LALVLTGVLIFALAL--FGNALVFYVVTRSKAMRTVTNIFICSLALSDLLITFFCIPVTM 103
Query: 99 VAIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICH--SMAYHRIYRRWH 156
+ D W G CK FV +V+ + +T IA+ R+ + H M + RR
Sbjct: 104 LQNISDNWLGGAFICKMVPFVQSTAVVTEILTMTCIAVERHQGLVHPFKMKWQYTNRRAF 163
Query: 157 TPLHICLIWLLTVVALLPNFFVGSLE------YDPRIYSCTFIQTASTQ---YTAAVVVI 207
T L + +WL+ V+ P + V LE Y+ C T+ YT ++VI
Sbjct: 164 TMLGV--VWLVAVIVGSPMWHVQQLEIKYDFLYEKEHICCLEEWTSPVHQKIYTTFILVI 221
Query: 208 HFLLPIAVVSFCYLRIWVLVLQARR----------KAKPESRLCLKPSDLRSFLTMFVVF 257
FLLP+ V+ Y +I + +R K S++ K R+ + M V
Sbjct: 222 LFLLPLMVMLILYSKIGYELWIKKRVGDGSVLRTIHGKEMSKIARKKK--RAVIMMVTVV 279
Query: 258 VIFAICWAPLNCIGLAVAIN--PQEMAPQIPEGLFVTSYLLAYFNSCLNAIVYGLLNQNF 315
+FA+CWAP + + + + + +E + +F ++ + NS N IVY +N+NF
Sbjct: 280 ALFAVCWAPFHVVHMMIEYSNFEKEYDDVTIKMIFAIVQIIGFSNSICNPIVYAFMNENF 339
Query: 316 RR 317
++
Sbjct: 340 KK 341
>gi|4557865 somatostatin receptor 5 [Homo sapiens]
Length = 364
Score = 117 bits (294), Expect = 1e-26
Identities = 99/348 (28%), Positives = 160/348 (45%), Gaps = 33/348 (9%)
Query: 23 SGAGSARPSRTPRPPWVAPAL--SAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLV 80
SG G R P P A A+ + ++ A + GN LVI VLR K++ N++++
Sbjct: 21 SGGGDNRTLVGPAPSAGARAVLVPVLYLLVCAAGLGGNTLVIYVVLRFAKMKTVTNIYIL 80
Query: 81 SLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYC 140
+LA+AD V+ P + W G C+ + G++ SVF +T ++++RY
Sbjct: 81 NLAVAD-VLYMLGLPFLATQNAASFWPFGPVLCRLVMTLDGVNQFTSVFCLTVMSVDRYL 139
Query: 141 YICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGSLEYDPRIYSCTFIQTASTQY 200
+ H ++ R R L W+L++ LP ++ +C
Sbjct: 140 AVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLPLLVFADVQEGG---TCNASWPEPVGL 196
Query: 201 TAAVVVIH-----FLLPIAVVSFCYLRIWVLVLQARRKAKPESRLCLKPSDLRSFLTM-F 254
AV +I+ F P+ V+ CYL I V V A + C++ R M
Sbjct: 197 WGAVFIIYTAVLGFFAPLLVICLCYLLIVVKVRAAGVRVG-----CVRRRSERKVTRMVL 251
Query: 255 VVFVIFAICWAP---LNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFNSCLNAIVYGLL 311
VV ++FA CW P +N + LAVA+ PQE A GL+ +L+Y NSC N ++YG L
Sbjct: 252 VVVLVFAGCWLPFFTVNIVNLAVAL-PQEPASA---GLYFFVVILSYANSCANPVLYGFL 307
Query: 312 NQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQA 359
+ NFR+ ++++L C++ S A+ + P P I Q +A
Sbjct: 308 SDNFRQSFQKVL--------CLRKGSGAKDADATE-PRPDRIRQQQEA 346
>gi|4758474 G protein-coupled receptor 10 [Homo sapiens]
Length = 370
Score = 117 bits (293), Expect = 2e-26
Identities = 93/324 (28%), Positives = 158/324 (48%), Gaps = 30/324 (9%)
Query: 23 SGAGSARPSRTP-RPPWVAPALSAVLI----VTTAVDVVGNLLVILSVLRNRKLRNAGNL 77
S AG+ P+ TP + + L +++ V V +VGN L++L + R R+L N N
Sbjct: 38 SVAGADAPAVTPFQSLQLVHQLKGLIVLLYSVVVVVGLVGNCLLVLVIARVRRLHNVTNF 97
Query: 78 FLVSLALADLVVAFYPYPLILVAIFYD-GWALGEEHCKASAFVMGLSVIGSVFNITAIAI 136
+ +LAL+D+++ PL L F GW G C F+ ++V SVF +T IA+
Sbjct: 98 LIGNLALSDVLMCTACVPLTLAYAFEPRGWVFGGGLCHLVFFLQPVTVYVSVFTLTTIAV 157
Query: 137 NRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLP----NFFVGSLEYDPRIYSCTF 192
+RY + H + RI R + + IW L+ V LP + V +D R+ F
Sbjct: 158 DRYVVLVHPLR-RRISLRL-SAYAVLAIWALSAVLALPAAVHTYHVELKPHDVRLCE-EF 214
Query: 193 IQTASTQ---YTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRLCLKPSDL-- 247
+ Q Y ++++ +LLP+ V+ Y+R+ V + R + P C+ S
Sbjct: 215 WGSQERQRQLYAWGLLLVTYLLPLLVILLSYVRVSV---KLRNRVVPG---CVTQSQADW 268
Query: 248 ------RSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFNS 301
R+F + VV V+FA+CW PL+ L ++P + P + + + LA ++
Sbjct: 269 DRARRRRTFCLLVVVVVVFAVCWLPLHVFNLLRDLDPHAIDPYAFGLVQLLCHWLAMSSA 328
Query: 302 CLNAIVYGLLNQNFRREYKRILLA 325
C N +Y L+ +FR E +++L+A
Sbjct: 329 CYNPFIYAWLHDSFREELRKLLVA 352
>gi|167000885 galanin receptor 1 [Homo sapiens]
Length = 349
Score = 116 bits (290), Expect = 4e-26
Identities = 82/280 (29%), Positives = 138/280 (49%), Gaps = 16/280 (5%)
Query: 52 AVDVVGNLLVILSVLRNR--KLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALG 109
A+ V+GN LVI + R++ K R+ NLF+++L++ADL + P W LG
Sbjct: 45 ALGVLGNSLVITVLARSKPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVYALPTWVLG 104
Query: 110 EEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTV 169
CK + +S++ S+F + A++++RY I HS + + L + IW L++
Sbjct: 105 AFICKFIHYFFTVSMLVSIFTLAAMSVDRYVAIVHSRRSSSLRVSRNALLGVGCIWALSI 164
Query: 170 VALLPNFFVGSLEYDPRIYSCTFI------QTASTQYTAAVVVIHFLLPIAVVSFCYLRI 223
P + L + PR + TF Y V +LLP+ ++ FCY ++
Sbjct: 165 AMASPVAYHQGL-FHPRASNQTFCWEQWPDPRHKKAYVVCTFVFGYLLPLLLICFCYAKV 223
Query: 224 WVLVLQARRKAKPESRLCLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAP 283
+ +K K S+ + S ++ T+ VV V+F I W P + I L + P
Sbjct: 224 ---LNHLHKKLKNMSKKS-EASKKKTAQTVLVVVVVFGISWLPHHIIHLWAEFGVFPLTP 279
Query: 284 QIPEGLF-VTSYLLAYFNSCLNAIVYGLLNQNFRREYKRI 322
LF +T++ LAY NS +N I+Y L++NFR+ YK++
Sbjct: 280 --ASFLFRITAHCLAYSNSSVNPIIYAFLSENFRKAYKQV 317
>gi|4507343 tachykinin receptor 1 isoform long [Homo sapiens]
Length = 407
Score = 115 bits (289), Expect = 5e-26
Identities = 77/301 (25%), Positives = 137/301 (45%), Gaps = 9/301 (2%)
Query: 27 SARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALAD 86
++ P++ +P W +A V VVGN++V+ +L ++++R N FLV+LA A+
Sbjct: 19 TSEPNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAE 78
Query: 87 LVVAFYPYPLILVAIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSM 146
+A + + ++ W G +CK F +V S++++TA+A +RY I H +
Sbjct: 79 ASMAAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPL 138
Query: 147 AYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGSLEYDPRIYSCTF------IQTASTQY 200
T + IC+IW+L ++ P + + E P C + Y
Sbjct: 139 QPR--LSATATKVVICVIWVLALLLAFPQGYYSTTETMPSRVVCMIEWPEHPNKIYEKVY 196
Query: 201 TAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRLCLKPSDLRSFLTMFVVFV-I 259
V V+ + LP+ V+ + Y + + + + R + S R + M +V V
Sbjct: 197 HICVTVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCT 256
Query: 260 FAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFNSCLNAIVYGLLNQNFRREY 319
FAICW P + L INP + + +++ LA ++ N I+Y LN FR +
Sbjct: 257 FAICWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMSSTMYNPIIYCCLNDRFRLGF 316
Query: 320 K 320
K
Sbjct: 317 K 317
>gi|149944554 somatostatin receptor 4 [Homo sapiens]
Length = 388
Score = 115 bits (287), Expect = 8e-26
Identities = 93/321 (28%), Positives = 153/321 (47%), Gaps = 42/321 (13%)
Query: 42 ALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALAD-LVVAFYPYPLILVA 100
A+ + + V +VGN LVI +LR K++ A N++L++LA+AD L + P+ A
Sbjct: 49 AIQCIYALVCLVGLVGNALVIFVILRYAKMKTATNIYLLNLAVADELFMLSVPFVASSAA 108
Query: 101 IFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLH 160
+ + W G C+A V GL++ SVF +T ++++RY + H + YRR
Sbjct: 109 LRH--WPFGSVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRA-ATYRRPSVAKL 165
Query: 161 ICL-IWLLTVVALLPNFFVGSLE--YDPRIYSCTFIQTASTQYTAAVVV----IHFLLPI 213
I L +WL +++ LP + +C +Q ++A VV + FLLP+
Sbjct: 166 INLGVWLASLLVTLPIAIFADTRPARGGQAVACN-LQWPHPAWSAVFVVYTFLLGFLLPV 224
Query: 214 AVVSFCYLRIWVLVLQARRKAKPESRLCLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLA 273
+ CYL I + +A + R + S+ + + +V V+F +CW P + L
Sbjct: 225 LAIGLCYLLIVGKMRAVALRAGWQQR---RRSEKKITRLVLMVVVVFVLCWMPFYVVQLL 281
Query: 274 VAINPQEMAPQIPEGLFVTSY---------LLAYFNSCLNAIVYGLLNQNFRREYKRILL 324
LFVTS +L+Y NSC N I+YG L+ NFRR ++R+L
Sbjct: 282 --------------NLFVTSLDATVNHVSLILSYANSCANPILYGFLSDNFRRFFQRVLC 327
Query: 325 ALWNPRHCIQDASKGSHAEGL 345
R C+ + + G+ E L
Sbjct: 328 L----RCCLLEGAGGAEEEPL 344
>gi|157364957 pancreatic polypeptide receptor 1 [Homo sapiens]
Length = 375
Score = 113 bits (283), Expect = 2e-25
Identities = 80/292 (27%), Positives = 140/292 (47%), Gaps = 19/292 (6%)
Query: 49 VTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWAL 108
+ T V V+GNL ++ +R ++ N NL + +LA +D ++ PL V D W
Sbjct: 50 IETVVGVLGNLCLMCVTVRQKEKANVTNLLIANLAFSDFLMCLLCQPLTAVYTIMDYWIF 109
Query: 109 GEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLT 168
GE CK SAF+ +SV S+ ++ +A+ R+ I + + + + L I LIW++
Sbjct: 110 GETLCKMSAFIQCMSVTVSILSLVLVALERHQLIINPTGWKPSISQAY--LGIVLIWVIA 167
Query: 169 VVALLP--------NFF----VGSLEYDPRIYSCTF---IQTASTQYTAAVVVIHFLLPI 213
V LP N F +LE+ CT + T YT +++ + LP+
Sbjct: 168 CVLSLPFLANSILENVFHKNHSKALEFLADKVVCTESWPLAHHRTIYTTFLLLFQYCLPL 227
Query: 214 AVVSFCYLRIWVLVLQARRKAKPESRLCLKPSDLRSFLTMFVVFVI-FAICWAPLNCIGL 272
+ CY RI+ LQ + + + L+ ++ + VV V+ FA+ W PL+
Sbjct: 228 GFILVCYARIY-RRLQRQGRVFHKGTYSLRAGHMKQVNVVLVVMVVAFAVLWLPLHVFNS 286
Query: 273 AVAINPQEMAPQIPEGLFVTSYLLAYFNSCLNAIVYGLLNQNFRREYKRILL 324
+ + + +F+ +LLA ++C+N +YG LN NF++E K ++L
Sbjct: 287 LEDWHHEAIPICHGNLIFLVCHLLAMASTCVNPFIYGFLNTNFKKEIKALVL 338
>gi|4557859 somatostatin receptor 2 [Homo sapiens]
Length = 369
Score = 112 bits (281), Expect = 4e-25
Identities = 79/292 (27%), Positives = 151/292 (51%), Gaps = 21/292 (7%)
Query: 43 LSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALAD-LVVAFYPYPLILVAI 101
L+ + V + + GN LVI +LR K++ N+++++LA+AD L + P+ + VA+
Sbjct: 46 LTFIYFVVCIIGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVAL 105
Query: 102 FYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHI 161
+ W G+ C+ V G++ S+F +T ++I+RY + H + + +RR T I
Sbjct: 106 VH--WPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAK-WRRPRTAKMI 162
Query: 162 CL-IWLLTVVALLPNFFVGSLEYDP-RIYSCT--FIQTASTQYTAAVV---VIHFLLPIA 214
+ +W ++++ +LP L + SCT + + YT ++ ++ FL+P+
Sbjct: 163 TMAVWGVSLLVILPIMIYAGLRSNQWGRSSCTINWPGESGAWYTGFIIYTFILGFLVPLT 222
Query: 215 VVSFCYLRIWVLVLQARRKAKPESRLCLKPSDLRSFLTMFVVFVIFAICWAPL---NCIG 271
++ CYL I + V + + R K S+ + + +V +F CW P N
Sbjct: 223 IICLCYLFIIIKVKSSGIRVGSSKR---KKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSS 279
Query: 272 LAVAINPQEMAPQIPEGLFVTSYLLAYFNSCLNAIVYGLLNQNFRREYKRIL 323
+++AI+P P + +G+F +L Y NSC N I+Y L+ NF++ ++ +L
Sbjct: 280 VSMAISP---TPAL-KGMFDFVVVLTYANSCANPILYAFLSDNFKKSFQNVL 327
>gi|7669546 tachykinin receptor 1 isoform short [Homo sapiens]
Length = 311
Score = 110 bits (274), Expect = 3e-24
Identities = 74/293 (25%), Positives = 133/293 (45%), Gaps = 9/293 (3%)
Query: 27 SARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALAD 86
++ P++ +P W +A V VVGN++V+ +L ++++R N FLV+LA A+
Sbjct: 19 TSEPNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAE 78
Query: 87 LVVAFYPYPLILVAIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSM 146
+A + + ++ W G +CK F +V S++++TA+A +RY I H +
Sbjct: 79 ASMAAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPL 138
Query: 147 AYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGSLEYDPRIYSCTF------IQTASTQY 200
T + IC+IW+L ++ P + + E P C + Y
Sbjct: 139 QPR--LSATATKVVICVIWVLALLLAFPQGYYSTTETMPSRVVCMIEWPEHPNKIYEKVY 196
Query: 201 TAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRLCLKPSDLRSFLTMFVVFV-I 259
V V+ + LP+ V+ + Y + + + + R + S R + M +V V
Sbjct: 197 HICVTVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCT 256
Query: 260 FAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFNSCLNAIVYGLLN 312
FAICW P + L INP + + +++ LA ++ N I+Y LN
Sbjct: 257 FAICWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMSSTMYNPIIYCCLN 309
>gi|223633971 G protein-coupled receptor 83 [Homo sapiens]
Length = 423
Score = 108 bits (269), Expect = 1e-23
Identities = 80/307 (26%), Positives = 141/307 (45%), Gaps = 26/307 (8%)
Query: 41 PALSAVLIVTTAVDVV----GNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPL 96
P + A+LIV + +V GN+LV + +N+++ +A +LF+V+LA+AD+++ P
Sbjct: 68 PTVKALLIVAYSFIIVFSLFGNVLVCHVIFKNQRMHSATSLFIVNLAVADIMITLLNTPF 127
Query: 97 ILVAIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWH 156
LV W G+ C S F S+ S +TAIA++R+ I H + +
Sbjct: 128 TLVRFVNSTWIFGKGMCHVSRFAQYCSLHVSALTLTAIAVDRHQVIMHPLKPRISITK-- 185
Query: 157 TPLHICLIWLLTVVALLPNFFVGSL---EYDPRIYSC----TFIQTASTQY---TAAVVV 206
++I +IW + LP+ L +Y I F + A + A +
Sbjct: 186 GVIYIAVIWTMATFFSLPHAICQKLFTFKYSEDIVRSLCLPDFPEPADLFWKYLDLATFI 245
Query: 207 IHFLLPIAVVSFCYLRI----WVLVLQARRKAKPESRLCLKPSDLRSFLTMFVVFVIFAI 262
+ ++LP+ ++S Y R+ W+ + E L+ ++ + +V V+FA+
Sbjct: 246 LLYILPLLIISVAYARVAKKLWLCNMIG--DVTTEQYFALRRKKKKTIKMLMLVVVLFAL 303
Query: 263 CWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFNSCLNAIVYGLLNQNFRREYKRI 322
CW PLNC L ++ + L+ + A ++C N +Y LN+NFR E K +
Sbjct: 304 CWFPLNCYVLLLS----SKVIRTNNALYFAFHWFAMSSTCYNPFIYCWLNENFRIELKAL 359
Query: 323 LLALWNP 329
L P
Sbjct: 360 LSMCQRP 366
>gi|223718055 opioid receptor, mu 1 isoform MOR-1H [Homo sapiens]
Length = 493
Score = 107 bits (266), Expect = 2e-23
Identities = 78/300 (26%), Positives = 138/300 (46%), Gaps = 30/300 (10%)
Query: 40 APALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILV 99
A + A+ + V + GN LV+ ++R K++ A N+++ +LALAD +A P V
Sbjct: 163 AITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALAD-ALATSTLPFQSV 221
Query: 100 AIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPL 159
W G CK + ++ S+F + ++++RY +CH + + TP
Sbjct: 222 NYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVK----ALDFRTPR 277
Query: 160 HICLI----WLLTVVALLPNFFVGSLEYDPRIYSCTFIQTASTQY-----TAAVVVIHFL 210
+ +I W+L+ LP F+ + +Y CT + T Y V + F+
Sbjct: 278 NAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFI 337
Query: 211 LPIAVVSFCYLRIWVLVLQARRKAKPESRLCLKPSDLRSFLTM-FVVFVIFAICWAPLNC 269
+P+ +++ CY + +L L++ R K +LR M VV +F +CW P++
Sbjct: 338 MPVLIITVCY-GLMILRLKSVRMLSGSKE---KDRNLRRITRMVLVVVAVFIVCWTPIHI 393
Query: 270 IGLAVAINPQEMAPQIPEGLFVT-----SYLLAYFNSCLNAIVYGLLNQNFRREYKRILL 324
+ A+ IPE F T L Y NSCLN ++Y L++NF+R ++ +
Sbjct: 394 YVIIKAL------VTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCI 447
>gi|117940060 opioid receptor, mu 1 isoform MOR-1 [Homo sapiens]
Length = 400
Score = 107 bits (266), Expect = 2e-23
Identities = 78/300 (26%), Positives = 138/300 (46%), Gaps = 30/300 (10%)
Query: 40 APALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILV 99
A + A+ + V + GN LV+ ++R K++ A N+++ +LALAD +A P V
Sbjct: 70 AITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALAD-ALATSTLPFQSV 128
Query: 100 AIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPL 159
W G CK + ++ S+F + ++++RY +CH + + TP
Sbjct: 129 NYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVK----ALDFRTPR 184
Query: 160 HICLI----WLLTVVALLPNFFVGSLEYDPRIYSCTFIQTASTQY-----TAAVVVIHFL 210
+ +I W+L+ LP F+ + +Y CT + T Y V + F+
Sbjct: 185 NAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFI 244
Query: 211 LPIAVVSFCYLRIWVLVLQARRKAKPESRLCLKPSDLRSFLTM-FVVFVIFAICWAPLNC 269
+P+ +++ CY + +L L++ R K +LR M VV +F +CW P++
Sbjct: 245 MPVLIITVCY-GLMILRLKSVRMLSGSKE---KDRNLRRITRMVLVVVAVFIVCWTPIHI 300
Query: 270 IGLAVAINPQEMAPQIPEGLFVT-----SYLLAYFNSCLNAIVYGLLNQNFRREYKRILL 324
+ A+ IPE F T L Y NSCLN ++Y L++NF+R ++ +
Sbjct: 301 YVIIKAL------VTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCI 354
>gi|223718712 opioid receptor, mu 1 isoform MOR-1B5 [Homo sapiens]
Length = 420
Score = 107 bits (266), Expect = 2e-23
Identities = 78/300 (26%), Positives = 138/300 (46%), Gaps = 30/300 (10%)
Query: 40 APALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILV 99
A + A+ + V + GN LV+ ++R K++ A N+++ +LALAD +A P V
Sbjct: 70 AITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALAD-ALATSTLPFQSV 128
Query: 100 AIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPL 159
W G CK + ++ S+F + ++++RY +CH + + TP
Sbjct: 129 NYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVK----ALDFRTPR 184
Query: 160 HICLI----WLLTVVALLPNFFVGSLEYDPRIYSCTFIQTASTQY-----TAAVVVIHFL 210
+ +I W+L+ LP F+ + +Y CT + T Y V + F+
Sbjct: 185 NAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFI 244
Query: 211 LPIAVVSFCYLRIWVLVLQARRKAKPESRLCLKPSDLRSFLTM-FVVFVIFAICWAPLNC 269
+P+ +++ CY + +L L++ R K +LR M VV +F +CW P++
Sbjct: 245 MPVLIITVCY-GLMILRLKSVRMLSGSKE---KDRNLRRITRMVLVVVAVFIVCWTPIHI 300
Query: 270 IGLAVAINPQEMAPQIPEGLFVT-----SYLLAYFNSCLNAIVYGLLNQNFRREYKRILL 324
+ A+ IPE F T L Y NSCLN ++Y L++NF+R ++ +
Sbjct: 301 YVIIKAL------VTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCI 354
>gi|223718719 opioid receptor, mu 1 isoform MOR-1B2 [Homo sapiens]
Length = 397
Score = 107 bits (266), Expect = 2e-23
Identities = 78/300 (26%), Positives = 138/300 (46%), Gaps = 30/300 (10%)
Query: 40 APALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILV 99
A + A+ + V + GN LV+ ++R K++ A N+++ +LALAD +A P V
Sbjct: 70 AITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALAD-ALATSTLPFQSV 128
Query: 100 AIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPL 159
W G CK + ++ S+F + ++++RY +CH + + TP
Sbjct: 129 NYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVK----ALDFRTPR 184
Query: 160 HICLI----WLLTVVALLPNFFVGSLEYDPRIYSCTFIQTASTQY-----TAAVVVIHFL 210
+ +I W+L+ LP F+ + +Y CT + T Y V + F+
Sbjct: 185 NAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFI 244
Query: 211 LPIAVVSFCYLRIWVLVLQARRKAKPESRLCLKPSDLRSFLTM-FVVFVIFAICWAPLNC 269
+P+ +++ CY + +L L++ R K +LR M VV +F +CW P++
Sbjct: 245 MPVLIITVCY-GLMILRLKSVRMLSGSKE---KDRNLRRITRMVLVVVAVFIVCWTPIHI 300
Query: 270 IGLAVAINPQEMAPQIPEGLFVT-----SYLLAYFNSCLNAIVYGLLNQNFRREYKRILL 324
+ A+ IPE F T L Y NSCLN ++Y L++NF+R ++ +
Sbjct: 301 YVIIKAL------VTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCI 354
>gi|223718077 opioid receptor, mu 1 isoform MOR-1B3 [Homo sapiens]
Length = 403
Score = 107 bits (266), Expect = 2e-23
Identities = 78/300 (26%), Positives = 138/300 (46%), Gaps = 30/300 (10%)
Query: 40 APALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILV 99
A + A+ + V + GN LV+ ++R K++ A N+++ +LALAD +A P V
Sbjct: 70 AITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALAD-ALATSTLPFQSV 128
Query: 100 AIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPL 159
W G CK + ++ S+F + ++++RY +CH + + TP
Sbjct: 129 NYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVK----ALDFRTPR 184
Query: 160 HICLI----WLLTVVALLPNFFVGSLEYDPRIYSCTFIQTASTQY-----TAAVVVIHFL 210
+ +I W+L+ LP F+ + +Y CT + T Y V + F+
Sbjct: 185 NAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFI 244
Query: 211 LPIAVVSFCYLRIWVLVLQARRKAKPESRLCLKPSDLRSFLTM-FVVFVIFAICWAPLNC 269
+P+ +++ CY + +L L++ R K +LR M VV +F +CW P++
Sbjct: 245 MPVLIITVCY-GLMILRLKSVRMLSGSKE---KDRNLRRITRMVLVVVAVFIVCWTPIHI 300
Query: 270 IGLAVAINPQEMAPQIPEGLFVT-----SYLLAYFNSCLNAIVYGLLNQNFRREYKRILL 324
+ A+ IPE F T L Y NSCLN ++Y L++NF+R ++ +
Sbjct: 301 YVIIKAL------VTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCI 354
>gi|223718716 opioid receptor, mu 1 isoform MOR-1B1 [Homo sapiens]
Length = 406
Score = 107 bits (266), Expect = 2e-23
Identities = 78/300 (26%), Positives = 138/300 (46%), Gaps = 30/300 (10%)
Query: 40 APALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILV 99
A + A+ + V + GN LV+ ++R K++ A N+++ +LALAD +A P V
Sbjct: 70 AITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALAD-ALATSTLPFQSV 128
Query: 100 AIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPL 159
W G CK + ++ S+F + ++++RY +CH + + TP
Sbjct: 129 NYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVK----ALDFRTPR 184
Query: 160 HICLI----WLLTVVALLPNFFVGSLEYDPRIYSCTFIQTASTQY-----TAAVVVIHFL 210
+ +I W+L+ LP F+ + +Y CT + T Y V + F+
Sbjct: 185 NAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFI 244
Query: 211 LPIAVVSFCYLRIWVLVLQARRKAKPESRLCLKPSDLRSFLTM-FVVFVIFAICWAPLNC 269
+P+ +++ CY + +L L++ R K +LR M VV +F +CW P++
Sbjct: 245 MPVLIITVCY-GLMILRLKSVRMLSGSKE---KDRNLRRITRMVLVVVAVFIVCWTPIHI 300
Query: 270 IGLAVAINPQEMAPQIPEGLFVT-----SYLLAYFNSCLNAIVYGLLNQNFRREYKRILL 324
+ A+ IPE F T L Y NSCLN ++Y L++NF+R ++ +
Sbjct: 301 YVIIKAL------VTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCI 354
>gi|15150803 opsin 4 isoform 1 [Homo sapiens]
Length = 478
Score = 107 bits (266), Expect = 2e-23
Identities = 84/316 (26%), Positives = 146/316 (46%), Gaps = 26/316 (8%)
Query: 20 PG-WSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLF 78
PG W+ A P+ P L V+++ ++GNL VI + R+R LR N+F
Sbjct: 50 PGTWAAAWVPLPT-VDVPDHAHYTLGTVILLVGLTGMLGNLTVIYTFCRSRSLRTPANMF 108
Query: 79 LVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINR 138
+++LA++D +++F P+ + Y W GE C+ AF L I S+ +TAIA++R
Sbjct: 109 IINLAVSDFLMSFTQAPVFFTSSLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDR 168
Query: 139 YCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGSLEYDPR--IYSCTF---- 192
Y I +A + + + +WL + LP FF G Y P + SC++
Sbjct: 169 YLVITRPLATFGVASKRRAAFVLLGVWLYALAWSLPPFF-GWSAYVPEGLLTSCSWDYMS 227
Query: 193 IQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARR--------KAKPES---RLC 241
A YT + F LP+ ++ +CY+ I+ + + R K ES R
Sbjct: 228 FTPAVRAYTMLLCCFVFFLPLLIIIYCYIFIFRAIRETGRALQTFGACKGNGESLWQRQR 287
Query: 242 LKPSDLRSFLTMFVVFVIFAICWAPLNCIGL-AVAINPQEMAPQIPEGLFVTSYLLAYFN 300
L+ S+ + M +V ++F + WAP + + L A A + P + ++A +
Sbjct: 288 LQ-SECKMAKIMLLVILLFVLSWAPYSAVALVAFAGYAHVLTPYMSS----VPAVIAKAS 342
Query: 301 SCLNAIVYGLLNQNFR 316
+ N I+Y + + +R
Sbjct: 343 AIHNPIIYAITHPKYR 358
>gi|117940058 opioid receptor, mu 1 isoform MOR-1A [Homo sapiens]
Length = 392
Score = 107 bits (266), Expect = 2e-23
Identities = 78/300 (26%), Positives = 138/300 (46%), Gaps = 30/300 (10%)
Query: 40 APALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILV 99
A + A+ + V + GN LV+ ++R K++ A N+++ +LALAD +A P V
Sbjct: 70 AITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALAD-ALATSTLPFQSV 128
Query: 100 AIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPL 159
W G CK + ++ S+F + ++++RY +CH + + TP
Sbjct: 129 NYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVK----ALDFRTPR 184
Query: 160 HICLI----WLLTVVALLPNFFVGSLEYDPRIYSCTFIQTASTQY-----TAAVVVIHFL 210
+ +I W+L+ LP F+ + +Y CT + T Y V + F+
Sbjct: 185 NAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFI 244
Query: 211 LPIAVVSFCYLRIWVLVLQARRKAKPESRLCLKPSDLRSFLTM-FVVFVIFAICWAPLNC 269
+P+ +++ CY + +L L++ R K +LR M VV +F +CW P++
Sbjct: 245 MPVLIITVCY-GLMILRLKSVRMLSGSKE---KDRNLRRITRMVLVVVAVFIVCWTPIHI 300
Query: 270 IGLAVAINPQEMAPQIPEGLFVT-----SYLLAYFNSCLNAIVYGLLNQNFRREYKRILL 324
+ A+ IPE F T L Y NSCLN ++Y L++NF+R ++ +
Sbjct: 301 YVIIKAL------VTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCI 354
>gi|223717969 opioid receptor, mu 1 isoform MOR-1B4 [Homo sapiens]
Length = 389
Score = 107 bits (266), Expect = 2e-23
Identities = 78/300 (26%), Positives = 138/300 (46%), Gaps = 30/300 (10%)
Query: 40 APALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILV 99
A + A+ + V + GN LV+ ++R K++ A N+++ +LALAD +A P V
Sbjct: 70 AITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALAD-ALATSTLPFQSV 128
Query: 100 AIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPL 159
W G CK + ++ S+F + ++++RY +CH + + TP
Sbjct: 129 NYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVK----ALDFRTPR 184
Query: 160 HICLI----WLLTVVALLPNFFVGSLEYDPRIYSCTFIQTASTQY-----TAAVVVIHFL 210
+ +I W+L+ LP F+ + +Y CT + T Y V + F+
Sbjct: 185 NAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFI 244
Query: 211 LPIAVVSFCYLRIWVLVLQARRKAKPESRLCLKPSDLRSFLTM-FVVFVIFAICWAPLNC 269
+P+ +++ CY + +L L++ R K +LR M VV +F +CW P++
Sbjct: 245 MPVLIITVCY-GLMILRLKSVRMLSGSKE---KDRNLRRITRMVLVVVAVFIVCWTPIHI 300
Query: 270 IGLAVAINPQEMAPQIPEGLFVT-----SYLLAYFNSCLNAIVYGLLNQNFRREYKRILL 324
+ A+ IPE F T L Y NSCLN ++Y L++NF+R ++ +
Sbjct: 301 YVIIKAL------VTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCI 354
>gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens]
Length = 397
Score = 107 bits (266), Expect = 2e-23
Identities = 82/322 (25%), Positives = 146/322 (45%), Gaps = 22/322 (6%)
Query: 43 LSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIF 102
++ VL V + V GN++V L+V NR+LRN N F+VSLA+ DL++ P +
Sbjct: 21 ITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGLLVLPFSAIYQL 80
Query: 103 YDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHIC 162
W+ G+ C + + S+ N+ I+++RYC + + Y + + +
Sbjct: 81 SCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRVAISLV 140
Query: 163 LIWLLTVVALLPNFFVGSLEYDPRIYSCTFIQTAS-------TQYTAAVVVIHFLLPIAV 215
LIW V+++ +F L ++ R + T S Y ++ F LP+ +
Sbjct: 141 LIW---VISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNEVYGLVDGLVTFYLPLLI 197
Query: 216 VSFCYLRIWVLVL-QARRKAKPESRLCLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAV 274
+ Y RI+ + QA+R S + ++ +T+ V F ICW P +
Sbjct: 198 MCITYYRIFKVARDQAKRINHISSWKAATIREHKATVTLAAVMGAFIICWFPYFTAFVYR 257
Query: 275 AINPQEMAPQIPEGLFVTSYLLAYFNSCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQ 334
+ + ++ E + + L Y NS LN I+Y LN++FR Y+++ C +
Sbjct: 258 GLRGDDAINEVLEAIVL---WLGYANSALNPILYAALNRDFRTGYQQLF--------CCR 306
Query: 335 DASKGSHAEGLQSPAPPIIGVQ 356
A++ SH L+S A + Q
Sbjct: 307 LANRNSHKTSLRSNASQLSRTQ 328
>gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens]
Length = 359
Score = 107 bits (266), Expect = 2e-23
Identities = 82/322 (25%), Positives = 146/322 (45%), Gaps = 22/322 (6%)
Query: 43 LSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIF 102
++ VL V + V GN++V L+V NR+LRN N F+VSLA+ DL++ P +
Sbjct: 21 ITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGLLVLPFSAIYQL 80
Query: 103 YDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHIC 162
W+ G+ C + + S+ N+ I+++RYC + + Y + + +
Sbjct: 81 SCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRVAISLV 140
Query: 163 LIWLLTVVALLPNFFVGSLEYDPRIYSCTFIQTAS-------TQYTAAVVVIHFLLPIAV 215
LIW V+++ +F L ++ R + T S Y ++ F LP+ +
Sbjct: 141 LIW---VISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNEVYGLVDGLVTFYLPLLI 197
Query: 216 VSFCYLRIWVLVL-QARRKAKPESRLCLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAV 274
+ Y RI+ + QA+R S + ++ +T+ V F ICW P +
Sbjct: 198 MCITYYRIFKVARDQAKRINHISSWKAATIREHKATVTLAAVMGAFIICWFPYFTAFVYR 257
Query: 275 AINPQEMAPQIPEGLFVTSYLLAYFNSCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQ 334
+ + ++ E + + L Y NS LN I+Y LN++FR Y+++ C +
Sbjct: 258 GLRGDDAINEVLEAIVL---WLGYANSALNPILYAALNRDFRTGYQQLF--------CCR 306
Query: 335 DASKGSHAEGLQSPAPPIIGVQ 356
A++ SH L+S A + Q
Sbjct: 307 LANRNSHKTSLRSNASQLSRTQ 328
>gi|117940055 opioid receptor, mu 1 isoform MOR-1O [Homo sapiens]
Length = 418
Score = 107 bits (266), Expect = 2e-23
Identities = 78/300 (26%), Positives = 138/300 (46%), Gaps = 30/300 (10%)
Query: 40 APALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILV 99
A + A+ + V + GN LV+ ++R K++ A N+++ +LALAD +A P V
Sbjct: 70 AITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALAD-ALATSTLPFQSV 128
Query: 100 AIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPL 159
W G CK + ++ S+F + ++++RY +CH + + TP
Sbjct: 129 NYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVK----ALDFRTPR 184
Query: 160 HICLI----WLLTVVALLPNFFVGSLEYDPRIYSCTFIQTASTQY-----TAAVVVIHFL 210
+ +I W+L+ LP F+ + +Y CT + T Y V + F+
Sbjct: 185 NAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFI 244
Query: 211 LPIAVVSFCYLRIWVLVLQARRKAKPESRLCLKPSDLRSFLTM-FVVFVIFAICWAPLNC 269
+P+ +++ CY + +L L++ R K +LR M VV +F +CW P++
Sbjct: 245 MPVLIITVCY-GLMILRLKSVRMLSGSKE---KDRNLRRITRMVLVVVAVFIVCWTPIHI 300
Query: 270 IGLAVAINPQEMAPQIPEGLFVT-----SYLLAYFNSCLNAIVYGLLNQNFRREYKRILL 324
+ A+ IPE F T L Y NSCLN ++Y L++NF+R ++ +
Sbjct: 301 YVIIKAL------VTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCI 354
>gi|117940054 opioid receptor, mu 1 isoform MOR-1X [Homo sapiens]
Length = 446
Score = 107 bits (266), Expect = 2e-23
Identities = 78/300 (26%), Positives = 138/300 (46%), Gaps = 30/300 (10%)
Query: 40 APALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILV 99
A + A+ + V + GN LV+ ++R K++ A N+++ +LALAD +A P V
Sbjct: 70 AITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALAD-ALATSTLPFQSV 128
Query: 100 AIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPL 159
W G CK + ++ S+F + ++++RY +CH + + TP
Sbjct: 129 NYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVK----ALDFRTPR 184
Query: 160 HICLI----WLLTVVALLPNFFVGSLEYDPRIYSCTFIQTASTQY-----TAAVVVIHFL 210
+ +I W+L+ LP F+ + +Y CT + T Y V + F+
Sbjct: 185 NAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFI 244
Query: 211 LPIAVVSFCYLRIWVLVLQARRKAKPESRLCLKPSDLRSFLTM-FVVFVIFAICWAPLNC 269
+P+ +++ CY + +L L++ R K +LR M VV +F +CW P++
Sbjct: 245 MPVLIITVCY-GLMILRLKSVRMLSGSKE---KDRNLRRITRMVLVVVAVFIVCWTPIHI 300
Query: 270 IGLAVAINPQEMAPQIPEGLFVT-----SYLLAYFNSCLNAIVYGLLNQNFRREYKRILL 324
+ A+ IPE F T L Y NSCLN ++Y L++NF+R ++ +
Sbjct: 301 YVIIKAL------VTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCI 354
>gi|4557861 somatostatin receptor 3 [Homo sapiens]
Length = 418
Score = 106 bits (265), Expect = 3e-23
Identities = 88/311 (28%), Positives = 140/311 (45%), Gaps = 30/311 (9%)
Query: 31 SRTPRPPWVAPA---LSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALAD- 86
S P P +A + + V +V V ++GN LVI VLR+ + N+++++LALAD
Sbjct: 32 SAGPSPAGLAVSGVLIPLVYLVVCVVGLLGNSLVIYVVLRHTASPSVTNVYILNLALADE 91
Query: 87 LVVAFYPYPLILVAIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSM 146
L + P+ A+ Y W G C+ V G++ S+F +T ++++RY + H
Sbjct: 92 LFMLGLPFLAAQNALSY--WPFGSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPT 149
Query: 147 AYHRIYRRWHTP----LHICLIWLLTVVALLPNFFVGSLEYDPRIYSCTFIQTASTQ--- 199
RW T +W+ + V +LP + PR S +Q
Sbjct: 150 RS----ARWRTAPVARTVSAAVWVASAVVVLPVVVFSGV---PRGMSTCHMQWPEPAAAW 202
Query: 200 ------YTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRLCLKPSDLRSFLTM 253
YTAA + F P+ V+ CYL I V V A R+ S + S+ R +
Sbjct: 203 RAGFIIYTAA---LGFFGPLLVICLCYLLIVVKVRSAGRRVWAPSCQRRRRSERRVTRMV 259
Query: 254 FVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFNSCLNAIVYGLLNQ 313
V +F +CW P + + + P P GL+ L Y NSC N I+YG L+
Sbjct: 260 VAVVALFVLCWMPFYVLNIVNVVCPLPEEPAF-FGLYFLVVALPYANSCANPILYGFLSY 318
Query: 314 NFRREYKRILL 324
F++ ++R+LL
Sbjct: 319 RFKQGFRRVLL 329
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.329 0.140 0.457
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,822,372
Number of Sequences: 37866
Number of extensions: 592930
Number of successful extensions: 3729
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 480
Number of HSP's successfully gapped in prelim test: 221
Number of HSP's that attempted gapping in prelim test: 2298
Number of HSP's gapped (non-prelim): 824
length of query: 362
length of database: 18,247,518
effective HSP length: 104
effective length of query: 258
effective length of database: 14,309,454
effective search space: 3691839132
effective search space used: 3691839132
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.