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Search of human proteins with 51702526
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
sapiens]
(505 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 1066 0.0
gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] 446 e-125
gi|11386183 WAS protein family, member 2 [Homo sapiens] 145 1e-34
gi|160707881 formin 2 [Homo sapiens] 130 4e-30
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 118 1e-26
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 118 1e-26
gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Ho... 116 5e-26
gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Ho... 116 5e-26
gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Ho... 116 5e-26
gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Hom... 116 5e-26
gi|13699803 WAS protein family, member 3 [Homo sapiens] 105 7e-23
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 104 2e-22
gi|56549694 enabled homolog isoform a [Homo sapiens] 104 2e-22
gi|39930375 enabled homolog isoform b [Homo sapiens] 104 2e-22
gi|33356148 formin-like 1 [Homo sapiens] 103 5e-22
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 102 6e-22
gi|7706501 WW domain binding protein 11 [Homo sapiens] 101 1e-21
gi|153792074 proline rich 12 [Homo sapiens] 101 1e-21
gi|149999378 inverted formin 2 isoform 2 [Homo sapiens] 101 2e-21
gi|149999380 inverted formin 2 isoform 1 [Homo sapiens] 101 2e-21
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 100 3e-21
gi|157168329 formin 1 [Homo sapiens] 100 4e-21
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 100 5e-21
gi|150417989 cyclin K isoform 1 [Homo sapiens] 100 5e-21
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 98 2e-20
gi|18959210 WIRE protein [Homo sapiens] 97 3e-20
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 96 8e-20
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 96 1e-19
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 96 1e-19
gi|56118221 amyloid beta (A4) precursor protein-binding, family ... 95 2e-19
>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
sapiens]
Length = 505
Score = 1066 bits (2758), Expect = 0.0
Identities = 505/505 (100%), Positives = 505/505 (100%)
Query: 1 MSSVQQQPPPPRRVTNVGSLLLTPQENESLFTFLGKKCVTMSSAVVQLYAADRNCMWSKK 60
MSSVQQQPPPPRRVTNVGSLLLTPQENESLFTFLGKKCVTMSSAVVQLYAADRNCMWSKK
Sbjct: 1 MSSVQQQPPPPRRVTNVGSLLLTPQENESLFTFLGKKCVTMSSAVVQLYAADRNCMWSKK 60
Query: 61 CSGVACLVKDNPQRSYFLRIFDIKDGKLLWEQELYNNFVYNSPRGYFHTFAGDTCQVALN 120
CSGVACLVKDNPQRSYFLRIFDIKDGKLLWEQELYNNFVYNSPRGYFHTFAGDTCQVALN
Sbjct: 61 CSGVACLVKDNPQRSYFLRIFDIKDGKLLWEQELYNNFVYNSPRGYFHTFAGDTCQVALN 120
Query: 121 FANEEEAKKFRKAVTDLLGRRQRKSEKRRDPPNGPNLPMATVDIKNPEITTNRFYGPQVN 180
FANEEEAKKFRKAVTDLLGRRQRKSEKRRDPPNGPNLPMATVDIKNPEITTNRFYGPQVN
Sbjct: 121 FANEEEAKKFRKAVTDLLGRRQRKSEKRRDPPNGPNLPMATVDIKNPEITTNRFYGPQVN 180
Query: 181 NISHTKEKKKGKAKKKRLTKADIGTPSNFQHIGHVGWDPNTGFDLNNLDPELKNLFDMCG 240
NISHTKEKKKGKAKKKRLTKADIGTPSNFQHIGHVGWDPNTGFDLNNLDPELKNLFDMCG
Sbjct: 181 NISHTKEKKKGKAKKKRLTKADIGTPSNFQHIGHVGWDPNTGFDLNNLDPELKNLFDMCG 240
Query: 241 ISEAQLKDRETSKVIYDFIEKTGGVEAVKNELRRQAPPPPPPSRGGPPPPPPPPHNSGPP 300
ISEAQLKDRETSKVIYDFIEKTGGVEAVKNELRRQAPPPPPPSRGGPPPPPPPPHNSGPP
Sbjct: 241 ISEAQLKDRETSKVIYDFIEKTGGVEAVKNELRRQAPPPPPPSRGGPPPPPPPPHNSGPP 300
Query: 301 PPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPP 360
PPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPP
Sbjct: 301 PPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPP 360
Query: 361 PPPSVLGVGPVAPPPPPPPPPPPGPPPPPGLPSDGDHQVPTTAGNKAALLDQIREGAQLK 420
PPPSVLGVGPVAPPPPPPPPPPPGPPPPPGLPSDGDHQVPTTAGNKAALLDQIREGAQLK
Sbjct: 361 PPPSVLGVGPVAPPPPPPPPPPPGPPPPPGLPSDGDHQVPTTAGNKAALLDQIREGAQLK 420
Query: 421 KVEQNSRPVSCSGRDALLDQIRQGIQLKSVADGQESTPPTPAPTSGIVGALMEVMQKRSK 480
KVEQNSRPVSCSGRDALLDQIRQGIQLKSVADGQESTPPTPAPTSGIVGALMEVMQKRSK
Sbjct: 421 KVEQNSRPVSCSGRDALLDQIRQGIQLKSVADGQESTPPTPAPTSGIVGALMEVMQKRSK 480
Query: 481 AIHSSDEDEDEDDEEDFEDDDEWED 505
AIHSSDEDEDEDDEEDFEDDDEWED
Sbjct: 481 AIHSSDEDEDEDDEEDFEDDDEWED 505
>gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]
Length = 502
Score = 446 bits (1147), Expect = e-125
Identities = 259/531 (48%), Positives = 319/531 (60%), Gaps = 90/531 (16%)
Query: 16 NVGSLLLTPQENESLFTFLGKKCVTMSSAVVQLYAA--DRNCMWSKKCSGVACLVKDNPQ 73
N+ S LL EN+ LF LG+KC+T+++AVVQLY A W+K+ G C VKDNPQ
Sbjct: 21 NIPSTLLQDHENQRLFEMLGRKCLTLATAVVQLYLALPPGAEHWTKEHCGAVCFVKDNPQ 80
Query: 74 RSYFLRIFDIKDGKLLWEQELYNNFVYNSPRGYFHTFAGDTCQVALNFANEEEAKKFRKA 133
+SYF+R++ ++ G+LLWEQELY+ VY++P +FHTFAGD CQ LNFA+E+EA+ FR
Sbjct: 81 KSYFIRLYGLQAGRLLWEQELYSQLVYSTPTPFFHTFAGDDCQAGLNFADEDEAQAFRAL 140
Query: 134 VTDLLGRR-QRKSEKRRD-----------------------------PPNGP-NLPMATV 162
V + + +R QR+S RR PP GP +L +ATV
Sbjct: 141 VQEKIQKRNQRQSGDRRQLPPPPTPANEERRGGLPPLPLHPGGDQGGPPVGPLSLGLATV 200
Query: 163 DIKNPEITTNRFYGPQVNNISHTKEKKKGKAKKKRLTKADIGTPSNFQHIGHVGWDPNTG 222
DI+NP+IT++R+ G S +K+ GK K+++KADIG PS F+H+ HVGWDP G
Sbjct: 201 DIQNPDITSSRYRGLPAPGPSPADKKRSGK---KKISKADIGAPSGFKHVSHVGWDPQNG 257
Query: 223 FDLNNLDPELKNLFDMCGISEAQLKDRETSKVIYDFIEKTGGVEAVKNELRRQAP--PPP 280
FD+NNLDP+L++LF GISEAQL D ETSK+IYDFIE GG+EAV+ E+RRQ P PPP
Sbjct: 258 FDVNNLDPDLRSLFSRAGISEAQLTDAETSKLIYDFIEDQGGLEAVRQEMRRQEPLPPPP 317
Query: 281 PPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPN 340
PPSRGG P PP +GR P PP P PPPP R PPPP
Sbjct: 318 PPSRGGNQLPRPPIVGGN------KGRSGPLPP---VPLGIAPPPPTPRG-----PPPPG 363
Query: 341 RMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPP----GPPPPPGLPSDGD 396
R PPPPP P++ SGP PPPP G GP PPPPPPPPPPP GP PPP P+
Sbjct: 364 RGGPPPPPP-PATGRSGPLPPPPPGAG-GPPMPPPPPPPPPPPSSGNGPAPPPLPPA--- 418
Query: 397 HQVPTTAGNKAALLDQIREGAQLKKVEQNSRPVSCSGRDALLDQIRQGIQLKSVADGQES 456
VP AG A GR ALLDQIRQGIQL ES
Sbjct: 419 -LVP--AGGLAP----------------------GGGRGALLDQIRQGIQLNKTPGAPES 453
Query: 457 TPPTPAPTS--GIVGALMEVMQKRSKAIHSSDEDEDEDDEEDFEDDDEWED 505
+ P P S G+VGALM VMQKRS+AIHSSDE ED+ +ED +DDEW+D
Sbjct: 454 SALQPPPQSSEGLVGALMHVMQKRSRAIHSSDEGEDQAGDED--EDDEWDD 502
>gi|11386183 WAS protein family, member 2 [Homo sapiens]
Length = 498
Score = 145 bits (365), Expect = 1e-34
Identities = 99/296 (33%), Positives = 124/296 (41%), Gaps = 75/296 (25%)
Query: 259 IEKTGGVEAVKNELRRQAPPPPPPSRGGPPPP-------PPPPHNSGPP----------- 300
+ + G + V+N PPPP P P PPPP P
Sbjct: 229 VYQNGSIGCVENVDASSYPPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAG 288
Query: 301 -----------PPPARGRGAPP-PPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMY----P 344
PPPA G+PP P P AP APPPPPP P + +PPPPP +
Sbjct: 289 PKRSSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPPPPPP--PMIGIPPPPPPVGFGSPGT 346
Query: 345 PPPPALPSSAP----SGPPPPPPSVLGVGPVAPPPP-----------PPPPPPPGPPPPP 389
PPPP+ PS P + PPPPPP P PPPP PPPPPPPGPPPPP
Sbjct: 347 PPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPPP 406
Query: 390 GLPSDGDHQVPTTAGNKAALLDQIREGAQLKKVEQNSRPVSCSGRDALLDQIRQGIQLKS 449
+DG +P + ++S P R LL IRQG QL+
Sbjct: 407 FTGADGQPAIPPPLSDTTK--------------PKSSLPAVSDARSDLLSAIRQGFQLRR 452
Query: 450 VADGQESTPPTPAPTSGIVGALMEVMQKRSKAIHSSDEDEDEDDEEDFEDDDEWED 505
V + +E +VG + + R A+ SD EDD +F D+D+W D
Sbjct: 453 VEEQREQ------EKRDVVGNDVATILSRRIAVEYSD---SEDDSSEF-DEDDWSD 498
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 130 bits (326), Expect = 4e-30
Identities = 72/140 (51%), Positives = 77/140 (55%), Gaps = 20/140 (14%)
Query: 277 PPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPP 336
PPPPP G PPPPP P PPPPP G G PPPPP P A PPPPP P +PP
Sbjct: 1086 PPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPP--LPGAGIPPPPPL-PGAGIPP 1142
Query: 337 PPP-NRMYPPPPPALPSSAPSGPPP-------PPPSVLGVGPVAPPPP------PPPPPP 382
PPP R+ PPPP LP + PPP PPP + GVG + PPPP PPPPP
Sbjct: 1143 PPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVG-IPPPPPLPGVGIPPPPPL 1201
Query: 383 PGP--PPPPGLPSDGDHQVP 400
PG PPPP LP G P
Sbjct: 1202 PGAGIPPPPPLPGMGIPPAP 1221
Score = 129 bits (324), Expect = 6e-30
Identities = 70/135 (51%), Positives = 74/135 (54%), Gaps = 20/135 (14%)
Query: 277 PPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPP 336
PPPPP G PPPPP P PPPPP G G PPPPP P A PPPPP P +PP
Sbjct: 1009 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP--LPGAGIPPPPPL-PGAGIPP 1065
Query: 337 PPP--NRMYPPPPPALPSSAPSGPP------PPPPSVLGVGPVAPPPP------PPPPPP 382
PPP PPPPP + P PP PPPP + GVG + PPPP PPPPP
Sbjct: 1066 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVG-IPPPPPLPGAGIPPPPPL 1124
Query: 383 PGP--PPPPGLPSDG 395
PG PPPP LP G
Sbjct: 1125 PGAGIPPPPPLPGAG 1139
Score = 128 bits (321), Expect = 1e-29
Identities = 71/144 (49%), Positives = 75/144 (52%), Gaps = 20/144 (13%)
Query: 277 PPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPP 336
PPPPP G PPPPP P PPPPP G G PPPPP P A PPPPP P +PP
Sbjct: 987 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP--LPGAGIPPPPPL-PGAGIPP 1043
Query: 337 PPP--NRMYPPPPPALPSSAPSGPP------PPPPSVLGVGPVAPPPP------PPPPPP 382
PPP PPPPP + P PP PPPP + G G + PPPP PPPPP
Sbjct: 1044 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG-IPPPPPLPGAGIPPPPPL 1102
Query: 383 PGP--PPPPGLPSDGDHQVPTTAG 404
PG PPPP LP G P G
Sbjct: 1103 PGVGIPPPPPLPGAGIPPPPPLPG 1126
Score = 128 bits (321), Expect = 1e-29
Identities = 72/144 (50%), Positives = 76/144 (52%), Gaps = 20/144 (13%)
Query: 277 PPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPP 336
PPPPP G PPPPP P PPPPP G G PPPPP P A PPPPP P V +PP
Sbjct: 1053 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP--LPGAGIPPPPPL-PGVGIPP 1109
Query: 337 PPP--NRMYPPPPPALPSSAPSGPP------PPPPSVLGVGPVAPPPP------PPPPPP 382
PPP PPPPP + P PP PPPP + VG + PPPP PPPPP
Sbjct: 1110 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVG-IPPPPPLPGAGIPPPPPL 1168
Query: 383 PGP--PPPPGLPSDGDHQVPTTAG 404
PG PPPP LP G P G
Sbjct: 1169 PGAGIPPPPPLPGVGIPPPPPLPG 1192
Score = 127 bits (320), Expect = 2e-29
Identities = 71/144 (49%), Positives = 75/144 (52%), Gaps = 20/144 (13%)
Query: 277 PPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPP 336
PPPPP G PPPPP P PPPPP G G PPPPP P A PPPPP P +PP
Sbjct: 1020 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP--LPGAGIPPPPPL-PGAGIPP 1076
Query: 337 PPP--NRMYPPPPPALPSSAPSGPP------PPPPSVLGVGPVAPPPP------PPPPPP 382
PPP PPPPP + P PP PPPP + G G + PPPP PPPPP
Sbjct: 1077 PPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAG-IPPPPPLPGAGIPPPPPL 1135
Query: 383 PGP--PPPPGLPSDGDHQVPTTAG 404
PG PPPP LP G P G
Sbjct: 1136 PGAGIPPPPPLPRVGIPPPPPLPG 1159
Score = 125 bits (314), Expect = 9e-29
Identities = 65/126 (51%), Positives = 69/126 (54%), Gaps = 10/126 (7%)
Query: 277 PPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPP 336
PPPPP G PPPPP P PPPPP G G PPPPP P A PPPPP P V +PP
Sbjct: 1130 PPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPP--LPGAGIPPPPPL-PGVGIPP 1186
Query: 337 PPP--NRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGPPPPPGLPSD 394
PPP PPPPP P PPPP + G+G P PP PPP G PPPP LP
Sbjct: 1187 PPPLPGVGIPPPPP-----LPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVS 1241
Query: 395 GDHQVP 400
G +P
Sbjct: 1242 GPPLLP 1247
Score = 124 bits (312), Expect = 2e-28
Identities = 69/138 (50%), Positives = 72/138 (52%), Gaps = 19/138 (13%)
Query: 277 PPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPP 336
PPPPP G PPPPP P PPPPP G G PPPPP P A PPPPP P +PP
Sbjct: 976 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP--LPGAGIPPPPPL-PGAGIPP 1032
Query: 337 PPP--NRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPP------PPPPPPPGP--P 386
PPP PPPPP P PPPP + G G + PPPP PPPPP PG P
Sbjct: 1033 PPPLPGAGIPPPPPL-----PGAGIPPPPPLPGAG-IPPPPPLPGAGIPPPPPLPGAGIP 1086
Query: 387 PPPGLPSDGDHQVPTTAG 404
PPP LP G P G
Sbjct: 1087 PPPPLPGAGIPPPPPLPG 1104
Score = 123 bits (308), Expect = 4e-28
Identities = 69/141 (48%), Positives = 74/141 (52%), Gaps = 29/141 (20%)
Query: 277 PPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPP 336
PPPPP G PPPPP P PPPPP G G PPPPP P A PPPPP P V +PP
Sbjct: 1097 PPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPP--LPGAGIPPPPPL-PRVGIPP 1153
Query: 337 PPP--NRMYPPPPPALPSSAPSGPP------PPPPSVLGVGPVAPPPP------PPPPP- 381
PPP PPPPP + P PP PPPP + GVG + PPPP PPPPP
Sbjct: 1154 PPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVG-IPPPPPLPGAGIPPPPPL 1212
Query: 382 ----------PPGPPPPPGLP 392
PP PPP G+P
Sbjct: 1213 PGMGIPPAPAPPLPPPGTGIP 1233
Score = 122 bits (307), Expect = 6e-28
Identities = 70/144 (48%), Positives = 75/144 (52%), Gaps = 21/144 (14%)
Query: 278 PPPPPSRGGPPPPPPPPHNSGPP-PPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPP 336
PPPPP G PPPPP +G P PPP G G PPPPP P A PPPPP P +PP
Sbjct: 943 PPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPP--LPGAGIPPPPPL-PGAGIPP 999
Query: 337 PPP--NRMYPPPPPALPSSAPSGPP------PPPPSVLGVGPVAPPPP------PPPPPP 382
PPP PPPPP + P PP PPPP + G G + PPPP PPPPP
Sbjct: 1000 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG-IPPPPPLPGAGIPPPPPL 1058
Query: 383 PGP--PPPPGLPSDGDHQVPTTAG 404
PG PPPP LP G P G
Sbjct: 1059 PGAGIPPPPPLPGAGIPPPPPLPG 1082
Score = 122 bits (305), Expect = 1e-27
Identities = 70/153 (45%), Positives = 74/153 (48%), Gaps = 26/153 (16%)
Query: 277 PPPPPPSRG-GPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPP--------PP 327
PPPPPP G G PPPPP P P PP G G PPPPP PPPP PP
Sbjct: 909 PPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPP 968
Query: 328 SRPSVAVPPPP--PNRMYPPPPPALPSSAPSGPP------PPPPSVLGVGPVAPPPP--- 376
P +PPPP P PPPPP + P PP PPPP + G G + PPPP
Sbjct: 969 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG-IPPPPPLPG 1027
Query: 377 ---PPPPPPPGP--PPPPGLPSDGDHQVPTTAG 404
PPPPP PG PPPP LP G P G
Sbjct: 1028 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1060
Score = 108 bits (269), Expect = 1e-23
Identities = 68/161 (42%), Positives = 76/161 (47%), Gaps = 26/161 (16%)
Query: 267 AVKNELRRQAPPPPP--------PSRGGPPPPPPP---------PHNSGPPPPPARGRGA 309
A KN +PPP P P G PPPPPP P + P PPP +G
Sbjct: 848 AFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEM 907
Query: 310 PPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVG 369
PPPP P A PPPPP + +P PP PPPP LP +A PPPPP G+
Sbjct: 908 LPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAI--PPPPPLPGAGI- 964
Query: 370 PVAPPPP----PPPPPPPGP--PPPPGLPSDGDHQVPTTAG 404
P+ PP P PPPPP PG PPPP LP G P G
Sbjct: 965 PLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1005
Score = 98.6 bits (244), Expect = 1e-20
Identities = 64/132 (48%), Positives = 66/132 (50%), Gaps = 23/132 (17%)
Query: 272 LRRQAPPPPPPSRG-GPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRP 330
L R PPPPP G G PPPPP P PPPPP G G PPPPP P PPPPP P
Sbjct: 1146 LPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPP--LPGVGIPPPPP-LP 1202
Query: 331 SVAVPPPPP-NRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGPPPPP 389
+PPPPP M PP PA PP PPP G G PPPP P GPP
Sbjct: 1203 GAGIPPPPPLPGMGIPPAPA--------PPLPPP---GTG----IPPPPLLPVSGPPL-- 1245
Query: 390 GLPSDGDHQVPT 401
LP G +PT
Sbjct: 1246 -LPQVGSSTLPT 1256
Score = 92.8 bits (229), Expect = 6e-19
Identities = 52/109 (47%), Positives = 55/109 (50%), Gaps = 8/109 (7%)
Query: 277 PPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPP 336
PPPPP G PPPPP P PPPPP G G PPPPP P A PPPPP P + +PP
Sbjct: 1163 PPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPP--LPGAGIPPPPPL-PGMGIPP 1219
Query: 337 PPPNRMYP-----PPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPP 380
P + P PPPP LP S P P S L V PPP P
Sbjct: 1220 APAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLP 1268
Score = 62.0 bits (149), Expect = 1e-09
Identities = 35/86 (40%), Positives = 38/86 (44%), Gaps = 14/86 (16%)
Query: 277 PPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPP-------------PPPSRAPTAAPP 323
PPPPP G PPPPP P PPPPP G G PP PPP P + PP
Sbjct: 1185 PPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPP 1244
Query: 324 PPPPSRPSVAVPPPPPNRMYPPPPPA 349
P S +P P PPP P+
Sbjct: 1245 LLPQVGSS-TLPTPQVCGFLPPPLPS 1269
Score = 45.4 bits (106), Expect = 1e-04
Identities = 53/182 (29%), Positives = 57/182 (31%), Gaps = 69/182 (37%)
Query: 281 PPSRGGPPPPP-PPPHNSGPPPP----------------------PARGRGAPPPPPS-- 315
PP G P PP PP SGP P + PPPPPS
Sbjct: 758 PPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSLL 817
Query: 316 -RAPTAAPPPPPPSRPSV--------AVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVL 366
A P PP S +V N P PP LP + S P
Sbjct: 818 WSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMP------ 871
Query: 367 GVGPVAPPPPPPPPPP-PG-----------------------PPPPPGLPSDGDHQVPTT 402
G+G V PPPPPP PG PPPPP LP G P
Sbjct: 872 GLGMV-----PPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPL 926
Query: 403 AG 404
G
Sbjct: 927 PG 928
Score = 36.6 bits (83), Expect = 0.055
Identities = 28/84 (33%), Positives = 32/84 (38%), Gaps = 15/84 (17%)
Query: 277 PPPPPPSRGGPPPP-----------PPPPHN--SGPPPPPARGRGAPPPPPSRAPTAAPP 323
PPPP P G PP P PPPP SGPP P G P P + PP
Sbjct: 1208 PPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTP--QVCGFLPP 1265
Query: 324 PPPPSRPSVAVPPPPPNRMYPPPP 347
P P + + +R P P
Sbjct: 1266 PLPSGLFGLGMNQDKGSRKQPIEP 1289
Score = 30.4 bits (67), Expect = 3.9
Identities = 28/103 (27%), Positives = 32/103 (31%), Gaps = 3/103 (2%)
Query: 286 GPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPP 345
G P PP P P G PS AP P + A+ P + P
Sbjct: 228 GAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEP 287
Query: 346 PPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPP---PPPPPGP 385
P P S P PS+ P A P P P GP
Sbjct: 288 REPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGP 330
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 118 bits (295), Expect = 1e-26
Identities = 69/154 (44%), Positives = 75/154 (48%), Gaps = 44/154 (28%)
Query: 277 PPPPPPSRGGPPPPPPPPHNSGPPPPPARG-------------RGAPPPPPSRAPTAAPP 323
PPPP P PPPPPPP PPPPP G PPPP PP
Sbjct: 588 PPPPAPGDSTTPPPPPPPP---PPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPP 644
Query: 324 PPP-------PSRPSV----AVPPPPP---NRMYPPPPPALPSSAPSGPPPPPPSVLGVG 369
PPP PS S+ A+PPPPP + PPPPP LP SA G PPPPP + G
Sbjct: 645 PPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSA--GIPPPPPPLPGEA 702
Query: 370 PVAPPPP--------PPPPPPPG----PPPPPGL 391
+ PPPP PPPPP PG PPPPPG+
Sbjct: 703 GMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGM 736
Score = 114 bits (286), Expect = 2e-25
Identities = 76/190 (40%), Positives = 90/190 (47%), Gaps = 39/190 (20%)
Query: 242 SEAQLKDRETSKVIYDFIEKTGGVEAVKNELRRQAP-----PPPPPSRGGPPPPPPPPHN 296
+E Q + E S++ + + T +E K E+ + PP PSR PP PP P +
Sbjct: 523 TEKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGD 582
Query: 297 SGP--PPPPARGRGAPPPPPSRAPTAAPPPP-------PPSRP-SVAVPPPPP---NRMY 343
SG PPPPA G PPPP P PP P PPS P A+ PPPP +
Sbjct: 583 SGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATI 642
Query: 344 PPPPP-------ALPSSAPSGPP-PPPPSVLGVGPVAPPPPP-------PPPPPP----- 383
PPPPP PSS P G PPPP + G + PPPPP PPPPPP
Sbjct: 643 PPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEA 702
Query: 384 -GPPPPPGLP 392
PPPPP LP
Sbjct: 703 GMPPPPPPLP 712
Score = 109 bits (273), Expect = 5e-24
Identities = 60/129 (46%), Positives = 63/129 (48%), Gaps = 16/129 (12%)
Query: 276 APPPPPPSRGGPPPPPPPPHNSGPPPPPAR--GRGAPPPPPSRAPTAAPPPPPPSRPSVA 333
+PPPP PPPPP P G P P + G PPPPP PPPPPP S
Sbjct: 631 SPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAG 690
Query: 334 VPPPPP----NRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPP---PPPPP--- 383
+PPPPP PPPPP LP PPPP P GP PPPPP PPPPP
Sbjct: 691 IPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPG----GPGIPPPPPGMGMPPPPPFGF 746
Query: 384 GPPPPPGLP 392
G P P LP
Sbjct: 747 GVPAAPVLP 755
Score = 56.6 bits (135), Expect = 5e-08
Identities = 31/68 (45%), Positives = 34/68 (50%), Gaps = 3/68 (4%)
Query: 262 TGGVEAVKNELRRQAP--PPPPPSRGGPPPPPPPPHNSGPP-PPPARGRGAPPPPPSRAP 318
+ G+ L +A PPPPP GGP PPPPP GP PPP G G PPPPP
Sbjct: 688 SAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFG 747
Query: 319 TAAPPPPP 326
A P P
Sbjct: 748 VPAAPVLP 755
Score = 37.4 bits (85), Expect = 0.032
Identities = 20/43 (46%), Positives = 20/43 (46%), Gaps = 9/43 (20%)
Query: 278 PPPPPSRGGP-----PP----PPPPPHNSGPPPPPARGRGAPP 311
PPPPP GGP PP PPPPP G P P G P
Sbjct: 718 PPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLPFGLTP 760
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 118 bits (295), Expect = 1e-26
Identities = 69/154 (44%), Positives = 75/154 (48%), Gaps = 44/154 (28%)
Query: 277 PPPPPPSRGGPPPPPPPPHNSGPPPPPARG-------------RGAPPPPPSRAPTAAPP 323
PPPP P PPPPPPP PPPPP G PPPP PP
Sbjct: 597 PPPPAPGDSTTPPPPPPPP---PPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPP 653
Query: 324 PPP-------PSRPSV----AVPPPPP---NRMYPPPPPALPSSAPSGPPPPPPSVLGVG 369
PPP PS S+ A+PPPPP + PPPPP LP SA G PPPPP + G
Sbjct: 654 PPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSA--GIPPPPPPLPGEA 711
Query: 370 PVAPPPP--------PPPPPPPG----PPPPPGL 391
+ PPPP PPPPP PG PPPPPG+
Sbjct: 712 GMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGM 745
Score = 114 bits (286), Expect = 2e-25
Identities = 76/190 (40%), Positives = 90/190 (47%), Gaps = 39/190 (20%)
Query: 242 SEAQLKDRETSKVIYDFIEKTGGVEAVKNELRRQAP-----PPPPPSRGGPPPPPPPPHN 296
+E Q + E S++ + + T +E K E+ + PP PSR PP PP P +
Sbjct: 532 TEKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGD 591
Query: 297 SGP--PPPPARGRGAPPPPPSRAPTAAPPPP-------PPSRP-SVAVPPPPP---NRMY 343
SG PPPPA G PPPP P PP P PPS P A+ PPPP +
Sbjct: 592 SGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATI 651
Query: 344 PPPPP-------ALPSSAPSGPP-PPPPSVLGVGPVAPPPPP-------PPPPPP----- 383
PPPPP PSS P G PPPP + G + PPPPP PPPPPP
Sbjct: 652 PPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEA 711
Query: 384 -GPPPPPGLP 392
PPPPP LP
Sbjct: 712 GMPPPPPPLP 721
Score = 109 bits (273), Expect = 5e-24
Identities = 60/129 (46%), Positives = 63/129 (48%), Gaps = 16/129 (12%)
Query: 276 APPPPPPSRGGPPPPPPPPHNSGPPPPPAR--GRGAPPPPPSRAPTAAPPPPPPSRPSVA 333
+PPPP PPPPP P G P P + G PPPPP PPPPPP S
Sbjct: 640 SPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAG 699
Query: 334 VPPPPP----NRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPP---PPPPP--- 383
+PPPPP PPPPP LP PPPP P GP PPPPP PPPPP
Sbjct: 700 IPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPG----GPGIPPPPPGMGMPPPPPFGF 755
Query: 384 GPPPPPGLP 392
G P P LP
Sbjct: 756 GVPAAPVLP 764
Score = 56.6 bits (135), Expect = 5e-08
Identities = 31/68 (45%), Positives = 34/68 (50%), Gaps = 3/68 (4%)
Query: 262 TGGVEAVKNELRRQAP--PPPPPSRGGPPPPPPPPHNSGPP-PPPARGRGAPPPPPSRAP 318
+ G+ L +A PPPPP GGP PPPPP GP PPP G G PPPPP
Sbjct: 697 SAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFG 756
Query: 319 TAAPPPPP 326
A P P
Sbjct: 757 VPAAPVLP 764
Score = 37.4 bits (85), Expect = 0.032
Identities = 20/43 (46%), Positives = 20/43 (46%), Gaps = 9/43 (20%)
Query: 278 PPPPPSRGGP-----PP----PPPPPHNSGPPPPPARGRGAPP 311
PPPPP GGP PP PPPPP G P P G P
Sbjct: 727 PPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLPFGLTP 769
>gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 116 bits (290), Expect = 5e-26
Identities = 94/298 (31%), Positives = 121/298 (40%), Gaps = 85/298 (28%)
Query: 272 LRRQAPPPPPPSRGGPPPPPPPPHNSGP-------PPPPARGRG----APPPPPSRAPTA 320
+R PPPPPP G P P S P PA GR +P PPP
Sbjct: 273 VRPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPP------ 326
Query: 321 APPPPPPS-------RPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAP 373
PPPP PS R S+ PPPP PPPPPA AP+ PPPP P + G + P
Sbjct: 327 -PPPPLPSALSTSSLRASMTSTPPPPVPP-PPPPPATALQAPAVPPPPAPLQIAPGVLHP 384
Query: 374 PPPP-----------------------------------PPPPPPGPPPPPGL------- 391
PPP PPPPPP P PPPG+
Sbjct: 385 APPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVT 444
Query: 392 ------PSDGDHQVPTTA-GNKAALL-----DQIREGAQLKKVEQNSRPVSCSGRDALLD 439
P G H P+TA G L+ Q+ ++ K+ ++ PV R LL+
Sbjct: 445 VTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKR-HPSTLPVISDARSVLLE 503
Query: 440 QIRQGIQLKSVADGQESTPPTPAPTSGIVGALMEVMQKRSKAIHSSDEDEDEDDEEDF 497
IR+GIQL+ V + +E A I + ++ +R +S ED+ E DE D+
Sbjct: 504 AIRKGIQLRKVEEQREQ----EAKHERIENDVATILSRRIAVEYSDSEDDSEFDEVDW 557
>gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 116 bits (290), Expect = 5e-26
Identities = 94/298 (31%), Positives = 121/298 (40%), Gaps = 85/298 (28%)
Query: 272 LRRQAPPPPPPSRGGPPPPPPPPHNSGP-------PPPPARGRG----APPPPPSRAPTA 320
+R PPPPPP G P P S P PA GR +P PPP
Sbjct: 273 VRPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPP------ 326
Query: 321 APPPPPPS-------RPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAP 373
PPPP PS R S+ PPPP PPPPPA AP+ PPPP P + G + P
Sbjct: 327 -PPPPLPSALSTSSLRASMTSTPPPPVPP-PPPPPATALQAPAVPPPPAPLQIAPGVLHP 384
Query: 374 PPPP-----------------------------------PPPPPPGPPPPPGL------- 391
PPP PPPPPP P PPPG+
Sbjct: 385 APPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVT 444
Query: 392 ------PSDGDHQVPTTA-GNKAALL-----DQIREGAQLKKVEQNSRPVSCSGRDALLD 439
P G H P+TA G L+ Q+ ++ K+ ++ PV R LL+
Sbjct: 445 VTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKR-HPSTLPVISDARSVLLE 503
Query: 440 QIRQGIQLKSVADGQESTPPTPAPTSGIVGALMEVMQKRSKAIHSSDEDEDEDDEEDF 497
IR+GIQL+ V + +E A I + ++ +R +S ED+ E DE D+
Sbjct: 504 AIRKGIQLRKVEEQREQ----EAKHERIENDVATILSRRIAVEYSDSEDDSEFDEVDW 557
>gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 116 bits (290), Expect = 5e-26
Identities = 94/298 (31%), Positives = 121/298 (40%), Gaps = 85/298 (28%)
Query: 272 LRRQAPPPPPPSRGGPPPPPPPPHNSGP-------PPPPARGRG----APPPPPSRAPTA 320
+R PPPPPP G P P S P PA GR +P PPP
Sbjct: 273 VRPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPP------ 326
Query: 321 APPPPPPS-------RPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAP 373
PPPP PS R S+ PPPP PPPPPA AP+ PPPP P + G + P
Sbjct: 327 -PPPPLPSALSTSSLRASMTSTPPPPVPP-PPPPPATALQAPAVPPPPAPLQIAPGVLHP 384
Query: 374 PPPP-----------------------------------PPPPPPGPPPPPGL------- 391
PPP PPPPPP P PPPG+
Sbjct: 385 APPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVT 444
Query: 392 ------PSDGDHQVPTTA-GNKAALL-----DQIREGAQLKKVEQNSRPVSCSGRDALLD 439
P G H P+TA G L+ Q+ ++ K+ ++ PV R LL+
Sbjct: 445 VTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKR-HPSTLPVISDARSVLLE 503
Query: 440 QIRQGIQLKSVADGQESTPPTPAPTSGIVGALMEVMQKRSKAIHSSDEDEDEDDEEDF 497
IR+GIQL+ V + +E A I + ++ +R +S ED+ E DE D+
Sbjct: 504 AIRKGIQLRKVEEQREQ----EAKHERIENDVATILSRRIAVEYSDSEDDSEFDEVDW 557
>gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 116 bits (290), Expect = 5e-26
Identities = 94/298 (31%), Positives = 121/298 (40%), Gaps = 85/298 (28%)
Query: 272 LRRQAPPPPPPSRGGPPPPPPPPHNSGP-------PPPPARGRG----APPPPPSRAPTA 320
+R PPPPPP G P P S P PA GR +P PPP
Sbjct: 273 VRPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPP------ 326
Query: 321 APPPPPPS-------RPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAP 373
PPPP PS R S+ PPPP PPPPPA AP+ PPPP P + G + P
Sbjct: 327 -PPPPLPSALSTSSLRASMTSTPPPPVPP-PPPPPATALQAPAVPPPPAPLQIAPGVLHP 384
Query: 374 PPPP-----------------------------------PPPPPPGPPPPPGL------- 391
PPP PPPPPP P PPPG+
Sbjct: 385 APPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVT 444
Query: 392 ------PSDGDHQVPTTA-GNKAALL-----DQIREGAQLKKVEQNSRPVSCSGRDALLD 439
P G H P+TA G L+ Q+ ++ K+ ++ PV R LL+
Sbjct: 445 VTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKR-HPSTLPVISDARSVLLE 503
Query: 440 QIRQGIQLKSVADGQESTPPTPAPTSGIVGALMEVMQKRSKAIHSSDEDEDEDDEEDF 497
IR+GIQL+ V + +E A I + ++ +R +S ED+ E DE D+
Sbjct: 504 AIRKGIQLRKVEEQREQ----EAKHERIENDVATILSRRIAVEYSDSEDDSEFDEVDW 557
>gi|13699803 WAS protein family, member 3 [Homo sapiens]
Length = 502
Score = 105 bits (263), Expect = 7e-23
Identities = 80/249 (32%), Positives = 106/249 (42%), Gaps = 41/249 (16%)
Query: 266 EAVKNELRRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPS---------- 315
+A ++E R + + P PPPPP PP P + + P P+
Sbjct: 280 QAAEHEYRPPSASARHMALNRPQQPPPPP----PPQAPEGSQASAPMAPADYGMLPAQII 335
Query: 316 ---RAPTAAPPPPPPSRPSVAVPPPPPNRM-YPPPPPALPSSAPSGPPPPPPSVLGVGPV 371
PPPPPP PS P +M PP PA SS + PP PP + G+
Sbjct: 336 EYYNPSGPPPPPPPPVIPSAQTAFVSPLQMPMQPPFPASASSTHAAPPHPPST--GLLVT 393
Query: 372 APPPPPPPPPPPGPP-PPPGLPSDGDHQVPTTAGNKAALLDQIREGAQLKKVEQNSRPVS 430
APPPP PPPPPPGPP P L S H P A+ K+ E P+S
Sbjct: 394 APPPPGPPPPPPGPPGPGSSLSSSPMHGPPV---------------AEAKRQEPAQPPIS 438
Query: 431 CSGRDALLDQIRQGIQLKSVADGQESTPPTPAPTSGIVGALMEVMQKRSKAIHSSDEDED 490
R LL IR GIQLK V + +E A + + ++ +R +S +D+
Sbjct: 439 -DARSDLLAAIRMGIQLKKVQEQREQ----EAKREPVGNDVATILSRRIAVEYSDSDDDS 493
Query: 491 EDDEEDFED 499
E DE D+ D
Sbjct: 494 EFDENDWSD 502
>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
Length = 538
Score = 104 bits (260), Expect = 2e-22
Identities = 84/283 (29%), Positives = 112/283 (39%), Gaps = 30/283 (10%)
Query: 243 EAQLKDRETSKVIYDFIEKTGGVEAVKNELRRQAPPPPPPSRGGPP------PPPPPPHN 296
E ++ R +V Y V+ R PP PP + G P PPP P
Sbjct: 74 EKLIQQRAVLRVSYKGSISYRNAARVQPPRRGATPPAPPRAPRGAPAAAAAAAPPPTP-- 131
Query: 297 SGPPPPPARGRGAPP---PPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSS 353
PPPPPA A P P + A APP P P++P P PP P A P+
Sbjct: 132 -APPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAV 190
Query: 354 APSGPP--PPPPSVLGVGPVAPPPPPPPPPP---PGPPPPPGLPSDGDHQVPTTAGNKAA 408
AP P PPP+V P PPPP PP PP PPP P P +G A +
Sbjct: 191 APPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEGGAVRAGGAARPVS 250
Query: 409 LLDQIR-------EGAQLKKVEQNSRPVSCSGRDALLDQIRQGIQLKSVADGQESTPPTP 461
L + +R G +L + + L++ R G D PP
Sbjct: 251 LREVVRYLGGSGGAGGRLTRGRVQGLLEEEAAARGRLERTRLGALALPRGDRPGRAPPAA 310
Query: 462 A--PTSGIVGALMEVMQKRSKAIHSSDEDEDEDDEEDFEDDDE 502
+ P+ G V++K + D+DEDED+E+D + E
Sbjct: 311 SARPSRSKRGGEERVLEKEEE----EDDDEDEDEEDDVSEGSE 349
Score = 100 bits (248), Expect = 4e-21
Identities = 80/261 (30%), Positives = 99/261 (37%), Gaps = 40/261 (15%)
Query: 274 RQAPPPPPPSRGGPPPPPP--------------PPHNSGPPPPPARGRGAPPPPPSRAPT 319
R A PP RG PP PP PP PPPPPA A P RA
Sbjct: 94 RNAARVQPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAA 153
Query: 320 AA---PPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPP--PPPPSVLGVGPVAPP 374
AA PP P P++P P PP P A P+ AP P PPP+V P PP
Sbjct: 154 AAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPP 213
Query: 375 PPPPPPPPPG---PPPPPGLPSDGDHQVPTTAGNKAALLDQIR-------EGAQLKKVEQ 424
PP PP PP PPP P P +G A +L + +R G +L +
Sbjct: 214 PPQPPAPPQQQQPPPPQPQPPPEGGAVRAGGAARPVSLREVVRYLGGSGGAGGRLTRGRV 273
Query: 425 NSRPVSCSGRDALLDQIRQGIQLKSVADGQESTPPTPAPTSGIVGALMEVMQKRSKAIHS 484
+ L++ R G D PP + RSK
Sbjct: 274 QGLLEEEAAARGRLERTRLGALALPRGDRPGRAPPAAS-----------ARPSRSKRGGE 322
Query: 485 SDEDEDEDDEEDFEDDDEWED 505
E E++E+D ED+DE +D
Sbjct: 323 ERVLEKEEEEDDDEDEDEEDD 343
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 104 bits (259), Expect = 2e-22
Identities = 72/194 (37%), Positives = 93/194 (47%), Gaps = 28/194 (14%)
Query: 309 APPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGV 368
APPPPP P PP P++ SVA+PPPP PPPPP LPS+ P PPPPPP V
Sbjct: 312 APPPPP-------PLPPGPAQASVALPPPPG----PPPPPPLPSTGPPPPPPPPPLPNQV 360
Query: 369 GPVAPPPPPPPPPPPGPPPPPGLPSDGDHQVPTTAGNKAALLDQIREGAQLKKVEQNSRP 428
PPPPPPPP PP P L S + P T G AA+ GA+L+KV +
Sbjct: 361 ----PPPPPPPPAPPLPASGFFLASMSEDNRPLT-GLAAAI-----AGAKLRKVSRMEDT 410
Query: 429 VSCSGRDALLDQIRQGI-QLKSVADGQESTPPTPAPTSGIVGALMEVMQKRSKAIHSSDE 487
SG +A+ G+ S D P P SG++ + ++ +R +
Sbjct: 411 SFPSGGNAI------GVNSASSKTDTGRGNGPLPLGGSGLMEEMSALLARRRRIAEKGST 464
Query: 488 DEDEDDEEDFEDDD 501
E E E+ ED +
Sbjct: 465 IETEQKEDKGEDSE 478
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 104 bits (259), Expect = 2e-22
Identities = 72/194 (37%), Positives = 93/194 (47%), Gaps = 28/194 (14%)
Query: 309 APPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGV 368
APPPPP P PP P++ SVA+PPPP PPPPP LPS+ P PPPPPP V
Sbjct: 312 APPPPP-------PLPPGPAQASVALPPPPG----PPPPPPLPSTGPPPPPPPPPLPNQV 360
Query: 369 GPVAPPPPPPPPPPPGPPPPPGLPSDGDHQVPTTAGNKAALLDQIREGAQLKKVEQNSRP 428
PPPPPPPP PP P L S + P T G AA+ GA+L+KV +
Sbjct: 361 ----PPPPPPPPAPPLPASGFFLASMSEDNRPLT-GLAAAI-----AGAKLRKVSRMEDT 410
Query: 429 VSCSGRDALLDQIRQGI-QLKSVADGQESTPPTPAPTSGIVGALMEVMQKRSKAIHSSDE 487
SG +A+ G+ S D P P SG++ + ++ +R +
Sbjct: 411 SFPSGGNAI------GVNSASSKTDTGRGNGPLPLGGSGLMEEMSALLARRRRIAEKGST 464
Query: 488 DEDEDDEEDFEDDD 501
E E E+ ED +
Sbjct: 465 IETEQKEDKGEDSE 478
>gi|33356148 formin-like 1 [Homo sapiens]
Length = 1100
Score = 103 bits (256), Expect = 5e-22
Identities = 54/112 (48%), Positives = 56/112 (50%), Gaps = 5/112 (4%)
Query: 282 PSRGGPPPPPPPPHNSGPPPPPARGRG---APPPPPSRAPTAAPPPPPPSRPSVAVPPPP 338
PS G P P P + P PA APPPPP +P PPS P A PP
Sbjct: 511 PSGGDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQA--PPL 568
Query: 339 PNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGPPPPPG 390
P PPP P LP P PPPPPP GPV PPPPPPPPPP GPP G
Sbjct: 569 PGSPEPPPAPPLPGDLPPPPPPPPPPPGTDGPVPPPPPPPPPPPGGPPDALG 620
Score = 77.0 bits (188), Expect = 4e-14
Identities = 42/88 (47%), Positives = 44/88 (50%), Gaps = 16/88 (18%)
Query: 276 APPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVP 335
APPPPPP G P P PP ++ P PP G PPP P P PPPPPP P
Sbjct: 541 APPPPPPLPGLPSPQEAPP-SAPPQAPPLPGSPEPPPAPP-LPGDLPPPPPP-------P 591
Query: 336 PPPPNRMYPPPPPALPSSAPSGPPPPPP 363
PPPP P PPP PPPPPP
Sbjct: 592 PPPPGTDGPVPPPP-------PPPPPPP 612
Score = 68.2 bits (165), Expect = 2e-11
Identities = 36/75 (48%), Positives = 36/75 (48%), Gaps = 16/75 (21%)
Query: 276 APPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVP 335
APP PP G P PPP PP PPPP PPPPP PPPPPP P
Sbjct: 561 APPQAPPLPGSPEPPPAPPLPGDLPPPPP-----PPPPPPGTDGPVPPPPPP-------P 608
Query: 336 PPPPNRMYPPPPPAL 350
PPPP PP AL
Sbjct: 609 PPPPG----GPPDAL 619
Score = 62.8 bits (151), Expect = 7e-10
Identities = 41/99 (41%), Positives = 46/99 (46%), Gaps = 17/99 (17%)
Query: 300 PPPPARGRGAPPPPPSRAPTAAPPPP--PPSRPSVAVPPPPPNRMYPPPPPALPS---SA 354
P A G P P PT +P P P + P+ PPPP PP P LPS +
Sbjct: 505 PVAVATPSGGDAPTPG-VPTGSPSPDLAPAAEPAPGAAPPPP-----PPLPGLPSPQEAP 558
Query: 355 PSGPPPPPPSVLGVGPVAPPPPPPPP-PPPGPPPPPGLP 392
PS PP PP P +P PPP PP P PPPPP P
Sbjct: 559 PSAPPQAPPL-----PGSPEPPPAPPLPGDLPPPPPPPP 592
Score = 46.2 bits (108), Expect = 7e-05
Identities = 38/120 (31%), Positives = 45/120 (37%), Gaps = 18/120 (15%)
Query: 304 ARGRGAPPPPPSRAPTAAPPPPPPSRPSVA-VPPPPPNRMYPPPPPALPS-------SAP 355
A G PP P +AP AAP P V + R+ P A+ + P
Sbjct: 452 AMGASRRPPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEILPVAVATP 511
Query: 356 SGPPPPPPSVL------GVGPVAPPPP----PPPPPPPGPPPPPGLPSDGDHQVPTTAGN 405
SG P P V + P A P P PPPPP PG P P P Q P G+
Sbjct: 512 SGGDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGS 571
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 102 bits (255), Expect = 6e-22
Identities = 64/164 (39%), Positives = 71/164 (43%), Gaps = 33/164 (20%)
Query: 275 QAPPPPPPSRGGPPP--------PPPPPHNSGPPPPPARGRG--APP-----PPPSRAPT 319
Q PPPPP GPPP PPPP GPPP + R +PP PPP
Sbjct: 48 QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQ 107
Query: 320 AAPPPPPPSRPSVAVP--------PPPPNRMYPPPPPALPSSAPSGPP-----PPPPSVL 366
PPPPP +P P PPPP + PPP S +P PP PPP
Sbjct: 108 PQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQG-- 165
Query: 367 GVGPVAPPPP---PPPPPPPGPPPPPGLPSDGDHQVPTTAGNKA 407
G P PPPP P PPP G P G P G Q P G+K+
Sbjct: 166 GNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKS 209
Score = 100 bits (249), Expect = 3e-21
Identities = 62/159 (38%), Positives = 68/159 (42%), Gaps = 29/159 (18%)
Query: 275 QAPPPPPPSRGGPPP--------PPPPPHNSGPPPPPARGRG--APP-----PPPSRAPT 319
Q PPPPP GPPP PPPP GPPP + R +PP PPP
Sbjct: 109 QGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQ 168
Query: 320 AAPPPPPPSRPSVAVP--------PPPPNRMYPPPPP---ALPSSAPSGPPPPPPSVLGV 368
PPPPP +P P PPPP + PPP + S +P G P PP G
Sbjct: 169 PQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGN 228
Query: 369 GPVAPPPP---PPPPPPPGPPPPPGLPSDGDHQVPTTAG 404
P PPPP P PPP G P G P G Q P G
Sbjct: 229 QPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQG 267
Score = 92.4 bits (228), Expect = 8e-19
Identities = 57/155 (36%), Positives = 62/155 (40%), Gaps = 35/155 (22%)
Query: 275 QAPPPPPPSRGGPPP--------PPPPPHNSGPPPPPARGRGA--PP-----PPPSRAPT 319
Q PPPPP GPPP PPPP GPPP + R + PP PPP
Sbjct: 170 QGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQ 229
Query: 320 AAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPS-------------GPPPPPPSVL 366
PPPPP +P PP N+ PPPP P P+ G P PP
Sbjct: 230 PQGPPPPPGKPQ-GPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQE 288
Query: 367 GVGPVAPPPPP------PPPPPPGPPPPPGLPSDG 395
G P PPPP P PP G P P P G
Sbjct: 289 GNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQG 323
Score = 82.0 bits (201), Expect = 1e-15
Identities = 53/145 (36%), Positives = 61/145 (42%), Gaps = 33/145 (22%)
Query: 277 PPPPPPSRGGPPPPPPPPHNSGPPPPPARGR---GAPPPPPSRAP---------TAAPP- 323
P PPP G P PPPP PPP G+ G PPP + P + +PP
Sbjct: 158 PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPG 217
Query: 324 ----PPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPP-----PPSVLG---VGPV 371
PPP PPPPP + PPP + P GPPPP PP+ G
Sbjct: 218 KPQGPPPQGGNQPQGPPPPPGKPQGPPPQG--GNKPQGPPPPGKPQGPPAQGGSKSQSAR 275
Query: 372 APPPPPPPPP------PPGPPPPPG 390
+PP P PP P GPPPP G
Sbjct: 276 SPPGKPQGPPQQEGNNPQGPPPPAG 300
Score = 80.5 bits (197), Expect = 3e-15
Identities = 50/133 (37%), Positives = 55/133 (41%), Gaps = 24/133 (18%)
Query: 281 PPSRGGPPPPPPPPHNSG---PPPPPARGRGAPPPPPSRAPTAAPPP-----PPPSRPSV 332
P G P P P + PPPPP + +G PPP P PPP PPP
Sbjct: 29 PSLIAGNPQGPSPQGGNKPQGPPPPPGKPQG-PPPQGGNKPQGPPPPGKPQGPPPQGDKS 87
Query: 333 AVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVA---PPPPPPPPPPPGPPP-- 387
P PP + PPP + P GPPPPP G P P PPPP P GPPP
Sbjct: 88 RSPRSPPGKPQGPPPQG--GNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQG 145
Query: 388 --------PPGLP 392
PPG P
Sbjct: 146 DKSRSPRSPPGKP 158
Score = 78.2 bits (191), Expect = 2e-14
Identities = 53/146 (36%), Positives = 58/146 (39%), Gaps = 36/146 (24%)
Query: 275 QAPPPPPPSRGGPP--------------PPPPPPHNS----GPPPPPARGRGAPPPPPSR 316
Q PPPP +G PP P PPP GPPPPP + +G PPP
Sbjct: 191 QGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQG-PPPQGGN 249
Query: 317 APTAAPPPPPPSRP-------SVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVG 369
P PPP P P S + PP P PP + P GPPPP G
Sbjct: 250 KPQGPPPPGKPQGPPAQGGSKSQSARSPPGK---PQGPPQQEGNNPQGPPPP-----AGG 301
Query: 370 PVAPPPPPPPPPPPGPPPPP--GLPS 393
P PP P GPP PP G PS
Sbjct: 302 NPQQPQAPPAGQPQGPPRPPQGGRPS 327
Score = 76.3 bits (186), Expect = 6e-14
Identities = 51/131 (38%), Positives = 55/131 (41%), Gaps = 24/131 (18%)
Query: 285 GGPPPPPPPPHNS--GPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRM 342
G P P P N GPPPPP + +G PPP P PPP P P PP
Sbjct: 34 GNPQGPSPQGGNKPQGPPPPPGKPQG-PPPQGGNKPQGPPPPGKPQGP----PPQGDKSR 88
Query: 343 YPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPP-PPPGPPP-----PPGLPSDGD 396
P PP P GPPP G P PPPPP P GPPP P G P G
Sbjct: 89 SPRSPPG----KPQGPPPQ-------GGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGK 137
Query: 397 HQVPTTAGNKA 407
Q P G+K+
Sbjct: 138 PQGPPPQGDKS 148
Score = 40.4 bits (93), Expect = 0.004
Identities = 18/36 (50%), Positives = 20/36 (55%), Gaps = 2/36 (5%)
Query: 279 PPPPSRGGPPPPPPPPHNS--GPPPPPARGRGAPPP 312
PPPP+ G P P PP GPP PP GR + PP
Sbjct: 295 PPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 330
Score = 39.7 bits (91), Expect = 0.006
Identities = 21/59 (35%), Positives = 25/59 (42%), Gaps = 1/59 (1%)
Query: 273 RRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPS 331
+ Q+ PP G PP + GPPPP P PP+ P P PP RPS
Sbjct: 270 KSQSARSPPGKPQG-PPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPS 327
>gi|7706501 WW domain binding protein 11 [Homo sapiens]
Length = 641
Score = 101 bits (252), Expect = 1e-21
Identities = 60/127 (47%), Positives = 63/127 (49%), Gaps = 17/127 (13%)
Query: 273 RRQAPPP--PPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRP 330
++QAPP PP PP P PPP GPPP APP P PT PP PPP P
Sbjct: 389 QQQAPPQSVPPSQIQAPPMPGPPP--LGPPP-------APPLRPPGPPTGLPPGPPPGAP 439
Query: 331 SVAVPPPPPNRMYPPP---PPALPSSAPSGPPPPPPSVLGVGPV--APPPPPPPPPPPG- 384
PP P P P PP P P GPPP PP L GP PPP PPP PPG
Sbjct: 440 PFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGI 499
Query: 385 PPPPPGL 391
PPP PG+
Sbjct: 500 PPPRPGM 506
Score = 92.0 bits (227), Expect = 1e-18
Identities = 62/147 (42%), Positives = 66/147 (44%), Gaps = 42/147 (28%)
Query: 275 QAPPPPPPSRGGPPPPPP-----PPHNSGPPPPPARGRGAPP------------------ 311
QAPP P P GPPP PP PP P PPP GAPP
Sbjct: 403 QAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPP----GAPPFLRPPGMPGLRGPLPRLL 458
Query: 312 ---PPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGV 368
PPP R P PP PPP P P PPP PPP LP AP G PPP P ++
Sbjct: 459 PPGPPPGRPP-GPPPGPPPGLP----PGPPPR----GPPPRLPPPAPPGIPPPRPGMMR- 508
Query: 369 GPVAPPPPPPPPP--PPGPPPPPGLPS 393
P+ PP P PP PP P P PG+ S
Sbjct: 509 PPLVPPLGPAPPGLFPPAPLPNPGVLS 535
Score = 75.1 bits (183), Expect = 1e-13
Identities = 47/113 (41%), Positives = 54/113 (47%), Gaps = 21/113 (18%)
Query: 264 GVEAVKNELRRQAPPPPPPSR-GGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAP 322
G+ ++ L R PP PPP R GPPP PPP PP PP RG PP R P AP
Sbjct: 446 GMPGLRGPLPRLLPPGPPPGRPPGPPPGPPP---GLPPGPPPRG------PPPRLPPPAP 496
Query: 323 PPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPP 375
P PP RP + PP + PP PA P P P P P G ++ PP
Sbjct: 497 PGIPPPRPGMMRPP-----LVPPLGPAPPGLFPPAPLPNP------GVLSAPP 538
Score = 72.0 bits (175), Expect = 1e-12
Identities = 41/87 (47%), Positives = 44/87 (50%), Gaps = 6/87 (6%)
Query: 312 PPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPP---PPALPSSAPSG-PPPPPPSVLG 367
PP S P+ PP P P + PP PP R PP PP P AP PP P + G
Sbjct: 393 PPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRG 452
Query: 368 VGPVAPPPPPPPPPPPGPP--PPPGLP 392
P PP PPP PPGPP PPPGLP
Sbjct: 453 PLPRLLPPGPPPGRPPGPPPGPPPGLP 479
Score = 38.1 bits (87), Expect = 0.019
Identities = 26/73 (35%), Positives = 31/73 (42%), Gaps = 5/73 (6%)
Query: 322 PPPPPPSRPS--VAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPP 379
P P P PS + P P PP L ++ GPP S+L + P PP
Sbjct: 140 PLPDMPHAPSNILIQDIPLPGAQ---PPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPG 196
Query: 380 PPPPGPPPPPGLP 392
PPGPPP P P
Sbjct: 197 RKPPGPPPGPPPP 209
Score = 37.0 bits (84), Expect = 0.042
Identities = 22/53 (41%), Positives = 22/53 (41%), Gaps = 12/53 (22%)
Query: 352 SSAPSGPPPPPPSVLGVGPVAPPPPP------PPPPPPGPP------PPPGLP 392
SS PP P P P PPP PP PPGPP PPPG P
Sbjct: 387 SSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAP 439
Score = 35.4 bits (80), Expect = 0.12
Identities = 21/45 (46%), Positives = 23/45 (51%), Gaps = 3/45 (6%)
Query: 352 SSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGPPP---PPGLPS 393
S+A S PP SV APP P PPP P P P PPG P+
Sbjct: 384 STASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPT 428
Score = 34.7 bits (78), Expect = 0.21
Identities = 19/49 (38%), Positives = 19/49 (38%), Gaps = 7/49 (14%)
Query: 286 GPPPPPPPPHNSGPPPP-------PARGRGAPPPPPSRAPTAAPPPPPP 327
G PP S PP P G G P PP R P PP PPP
Sbjct: 160 GAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPPPGPPP 208
Score = 30.4 bits (67), Expect = 3.9
Identities = 31/108 (28%), Positives = 37/108 (34%), Gaps = 29/108 (26%)
Query: 266 EAVKNELRRQAPPPPPPSRGGPPPPPPPPHN--------SGPPPPPARGRGAPPPPPSRA 317
+AVKN + P P P P N G PP + + PP+RA
Sbjct: 126 DAVKNAQHVEVESIPLPDM------PHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRA 179
Query: 318 PTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSV 365
+ P VP PP R P PPP PPPP V
Sbjct: 180 VSILP------LLGHGVPRLPPGRKPPGPPPG---------PPPPQVV 212
Score = 30.0 bits (66), Expect = 5.1
Identities = 20/52 (38%), Positives = 22/52 (42%), Gaps = 7/52 (13%)
Query: 276 APPPPPPSRGG-------PPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTA 320
APP PP R G PP P PP P P P G + PP + P A
Sbjct: 495 APPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPGVLSAPPNLIQRPKA 546
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 101 bits (252), Expect = 1e-21
Identities = 59/137 (43%), Positives = 66/137 (48%), Gaps = 27/137 (19%)
Query: 278 PPPPPSRGGPPPPP----PPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVA 333
PP P+ P PPP P +++G P PP PP PP APT P PPP
Sbjct: 1422 PPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPP-APTPQPQPPP------- 1473
Query: 334 VPPPPPNRMYPPPPPAL---PSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPP-----PGP 385
PPPPP P PPP + PSS P P PPPP P A P PPPPPPP P
Sbjct: 1474 -PPPPPQPALPSPPPLVAPTPSSPPPPPLPPPP------PPAMPSPPPPPPPAAAPLAAP 1526
Query: 386 PPPPGLPSDGDHQVPTT 402
P P PS D ++P T
Sbjct: 1527 PEEPAAPSPEDPELPDT 1543
Score = 90.5 bits (223), Expect = 3e-18
Identities = 51/114 (44%), Positives = 57/114 (50%), Gaps = 21/114 (18%)
Query: 272 LRRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPS 331
L + PP PPP+ P PPPPP PPP PA P PPP APT + PPPPP
Sbjct: 1453 LEEKPPPTPPPAPTPQPQPPPPP----PPPQPA----LPSPPPLVAPTPSSPPPPP---- 1500
Query: 332 VAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGP 385
PPPPP PPPPP P++AP PP P+ AP P P P P
Sbjct: 1501 -LPPPPPPAMPSPPPPPP-PAAAPLAAPPEEPA-------APSPEDPELPDTRP 1545
Score = 88.6 bits (218), Expect = 1e-17
Identities = 54/137 (39%), Positives = 63/137 (45%), Gaps = 29/137 (21%)
Query: 266 EAVKNELRRQAPPP--PPPSRGGPPPPPPPPHNSGPPPPP------ARGRGAPPPPP-SR 316
E++ + + PP P P PP P + P PPP A G P PP
Sbjct: 1396 ESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEE 1455
Query: 317 APTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPP 376
P PPP P +P PPPPP PPP PALPS PP ++ P +PPPP
Sbjct: 1456 KPPPTPPPAPTPQPQ---PPPPP----PPPQPALPS---------PPPLVAPTPSSPPPP 1499
Query: 377 PPPPPP----PGPPPPP 389
P PPPP P PPPPP
Sbjct: 1500 PLPPPPPPAMPSPPPPP 1516
Score = 70.9 bits (172), Expect = 3e-12
Identities = 60/188 (31%), Positives = 74/188 (39%), Gaps = 31/188 (16%)
Query: 213 GHVGWDPNTGFDLNNLDPELKNLFDMCGISEAQLKDRETSKVIYDFIEKTGGVEAVKNEL 272
G G P T ++L DP+ +L + S A L + G A++ L
Sbjct: 678 GGAGGPPGTPYELAKEDPQRYHLQSVIRTS-ASLDE--------------GATAALELGL 722
Query: 273 RRQAPPPPPPSRGGPPPPPPPP----HNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPS 328
R P RGG P + +G A + +PPPPP PTA P P
Sbjct: 723 GRLKEKKKGPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPP---PTAQSTQPTPH 779
Query: 329 RPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVG---------PVAPPPPPPP 379
+ P + PPPPP L S S P P PS VG AP PPPPP
Sbjct: 780 GLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPP 839
Query: 380 PPPPGPPP 387
PPPP P P
Sbjct: 840 PPPPPPMP 847
Score = 70.9 bits (172), Expect = 3e-12
Identities = 92/355 (25%), Positives = 120/355 (33%), Gaps = 105/355 (29%)
Query: 139 GRRQRKSEKRRDPPNGPNLPMATVDIKNPEITTNRFYGPQVNNISHTKEKK-----KGKA 193
G R+R + + +GP P I+ E+ T GP + KK +G+
Sbjct: 1151 GPRRRGRKPTKAKRDGPPRPRGRPRIRPLEVPTTA--GPASASTPTDGAKKPRGRGRGRG 1208
Query: 194 KKK-----------RLTKADIGTPSNFQHIGHVGWDPNTGFDLNNLDPELKNLFDMCGIS 242
+K + K + P + +G D +G D N+LD L I
Sbjct: 1209 RKAEEAGGTRLEPLKPLKIKLSVPKAGEGLGTSSGDAISGTDHNSLDSSLTREKIEAKIK 1268
Query: 243 EAQLKDRET-SKVIYDFIE--KTGGVEAVKNELRRQAP-------PPPPPSRGGPPPPPP 292
E + K E S + F++ K+G + P PP P+RG P PP
Sbjct: 1269 EVEEKQPEMKSGFMASFLDFLKSGKRHPPLYQAGLTPPLSPPKSVPPSVPARGLQPQPPA 1328
Query: 293 PPHNSGPPPPPA--------------RGRGAPPP-------------------------- 312
P PPP A G G P P
Sbjct: 1329 TPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSV 1388
Query: 313 -------------------PPSRAPT-AAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPS 352
PP P + P PP P+ AVP PPP P LPS
Sbjct: 1389 AKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPL-------PGLPS 1441
Query: 353 SAPSGPPPPPPSVLGVGPVAPPPPP------PPPPPPGPPPPPGLPSDGDHQVPT 401
+ +G P PP +L P PP PP P PPPP PPP P LPS PT
Sbjct: 1442 ANSNGTPEPP--LLEEKP--PPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPT 1492
Score = 67.8 bits (164), Expect = 2e-11
Identities = 41/99 (41%), Positives = 48/99 (48%), Gaps = 12/99 (12%)
Query: 293 PPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPS 352
PP + G P G G PP PP+ P P P R S A P P + P PP LPS
Sbjct: 967 PPEDEGDPKA---GAGPPPGPPAYDPYG---PYCPGRASGAGPETPGLGLDPNKPPELPS 1020
Query: 353 SAPSGPPPPPPSVLGVGP--VAPPPPPPPPPPPGPPPPP 389
+ + P ++ GP APPPPPPPPPPP P P
Sbjct: 1021 TVNA----EPLGLIQSGPHQAAPPPPPPPPPPPAPASEP 1055
Score = 61.2 bits (147), Expect = 2e-09
Identities = 46/142 (32%), Positives = 59/142 (41%), Gaps = 22/142 (15%)
Query: 230 PELKNLFDMCGISEAQLKDRETSKVIYDFIEKTGGVEAVKNELRRQAPPPPP--PSRGGP 287
P L +C ++ L+D E S + +E+ G A ++ + PP P G
Sbjct: 924 PRFVPLTSIC-FPDSLLQDEERS--FFPTMEEMFGGGAA-DDYGKAGPPEDEGDPKAGAG 979
Query: 288 PPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSR------------PSVAVP 335
PPP PP ++ P P R GA P P PP PS P A P
Sbjct: 980 PPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAP 1039
Query: 336 PPPPNRMYPPPPPALPSSAPSG 357
PPPP PPPPP P+S P G
Sbjct: 1040 PPPP----PPPPPPAPASEPKG 1057
Score = 52.4 bits (124), Expect = 1e-06
Identities = 49/158 (31%), Positives = 54/158 (34%), Gaps = 31/158 (19%)
Query: 277 PPPPPPSRGGPPPPPPPPHN--------------------SGPPPPPARGRGAPPPPPSR 316
P PP R GPP PPPPP + S P G PPPP R
Sbjct: 221 PAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPER 280
Query: 317 A-PTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALP---SSAPSGPPPPPPSVLGVGPVA 372
A P RP+ A PPPP PPP AL S S P + L P+
Sbjct: 281 ALPRQDTVIKHYQRPASAQPPPP-----PPPAHALQHYLSCGGSYPSMGHRANLACSPLG 335
Query: 373 PPPPPPPPPPPGPPPPPGLP--SDGDHQVPTTAGNKAA 408
P P P P G + G P AG A
Sbjct: 336 GGEPSPGAGEPSKAGPSGATAGASGRATGPEAAGGGGA 373
Score = 49.7 bits (117), Expect = 6e-06
Identities = 48/160 (30%), Positives = 56/160 (35%), Gaps = 36/160 (22%)
Query: 282 PSRGGPPPPPPPPHNSGPPPPPARGRGAP----PPPPSRAPTAA--------PPPPPPSR 329
P + PPPPPPPP P P G +P P T++ PP P +
Sbjct: 1034 PHQAAPPPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKK 1093
Query: 330 ----------PSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPP 379
P R+ P P L SS S P P LG PP P P
Sbjct: 1094 LYAQEYEFEADEDKADVPADIRLNPRRLPDLVSSCRSRPALSP---LGDIDFCPPNPGPD 1150
Query: 380 PPP-----------PGPPPPPGLPSDGDHQVPTTAGNKAA 408
P GPP P G P +VPTTAG +A
Sbjct: 1151 GPRRRGRKPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASA 1190
Score = 49.7 bits (117), Expect = 6e-06
Identities = 50/187 (26%), Positives = 63/187 (33%), Gaps = 43/187 (22%)
Query: 272 LRRQAPPPPPPSRGG---PPPPPPPPHNSGPPPPPARGRGAPPPPPSRAP-TAAPPPPPP 327
+RR P S GG PPP P P PP P + PP + P TA P PP P
Sbjct: 1674 VRRSGQAKNPVSAGGSSAPPPKAPAP----PPKPETPEKTTSEKPPEQTPETAMPEPPAP 1729
Query: 328 SRPSVAVP---PPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVG-------PVAPPPPP 377
+PS+ P ++ P A SG P L G P A P
Sbjct: 1730 EKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLPKARPTKV 1789
Query: 378 PPPPPP------------------GPP-------PPPGLPSDGDHQVPTTAGNKAALLDQ 412
PPP GPP PG PS+ + VP A+ +
Sbjct: 1790 KAEPPPKKRKKWLKEAGGNATAGGGPPGSSSDSESSPGAPSEDERAVPGRLLKTRAMREM 1849
Query: 413 IREGAQL 419
R ++
Sbjct: 1850 YRSYVEM 1856
Score = 46.6 bits (109), Expect = 5e-05
Identities = 34/101 (33%), Positives = 38/101 (37%), Gaps = 28/101 (27%)
Query: 286 GPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPT---------AAPPPPPPSRPSV---- 332
G P PP+ GPP PPPPP PT AA S P +
Sbjct: 218 GLGPAQTPPYRPGPPD--------PPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFS 269
Query: 333 --AVPPPPPNRMYPPPPPAL-----PSSAPSGPPPPPPSVL 366
A PPPP R P + P+SA PPPPP L
Sbjct: 270 GAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHAL 310
Score = 45.1 bits (105), Expect = 2e-04
Identities = 37/112 (33%), Positives = 47/112 (41%), Gaps = 13/112 (11%)
Query: 303 PARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSS------APS 356
PA P P PS PP PP+ ++ P + P P +PSS A
Sbjct: 154 PASFGSRPFPVPSSLSLQDPPFSPPANGLLS--PHDVLHLKPSQAPTVPSSLGFERLAGG 211
Query: 357 GPPPPPPSVLGVGPVAPPPPPPPPPPPGPPPPPGLPSDGDHQVPTTAGNKAA 408
G P G+GP PP P PP P PPPP LP+ + ++A AA
Sbjct: 212 GVLGPA----GLGPAQTPPYRPGPPDP-PPPPRHLPTQFNLLASSSAAAAAA 258
Score = 44.7 bits (104), Expect = 2e-04
Identities = 38/122 (31%), Positives = 46/122 (37%), Gaps = 19/122 (15%)
Query: 281 PPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAP---TAAPPPPPPSRPSVAVPPP 337
P GGPP PP SGPPPP + P + P P P+ S +P
Sbjct: 473 PSYSGGPPQPP-----SGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTA 527
Query: 338 PPNRMYPP-PPPAL--------PSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGPPPP 388
P+ Y PAL PSS G P + + P+ PP PP G P
Sbjct: 528 SPSLSYSTGHSPALSGHGGGWGPSSLGGGGEASPSHI--IRPLQSPPATGRPPGVGSPGA 585
Query: 389 PG 390
PG
Sbjct: 586 PG 587
Score = 41.2 bits (95), Expect = 0.002
Identities = 47/153 (30%), Positives = 55/153 (35%), Gaps = 19/153 (12%)
Query: 323 PPPPPSRPSVAVPP--PPPNRMYPPPPPA--LPSSAPSGPPPPPPSVLG---------VG 369
P P PS S+ PP PP N + P PS AP+ PS LG +G
Sbjct: 161 PFPVPSSLSLQDPPFSPPANGLLSPHDVLHLKPSQAPT-----VPSSLGFERLAGGGVLG 215
Query: 370 PVAPPPPPPPPPPPGPPPPPGLPSDGDHQVPTTAGNKAALLDQIREGAQLKKVEQNSRPV 429
P P PP PGPP PP P Q A + AA + QL + P
Sbjct: 216 PAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNF-SGAAPG 274
Query: 430 SCSGRDALLDQIRQGIQLKSVADGQESTPPTPA 462
AL Q + A Q PP PA
Sbjct: 275 PPPPERALPRQDTVIKHYQRPASAQPPPPPPPA 307
Score = 35.8 bits (81), Expect = 0.094
Identities = 32/106 (30%), Positives = 37/106 (34%), Gaps = 8/106 (7%)
Query: 293 PPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPS 352
P + +G A GA PPP R+ TA P P+ A + A
Sbjct: 387 PGYKTGKGGYGAAAGGATRPPPPRS-TATPKCQSLGGPAAAYATGKASGAGGAGGQAYSP 445
Query: 353 SAPSGPPPPPPSVLGVG-------PVAPPPPPPPPPPPGPPPPPGL 391
P G P G G AP PP PP PPPPGL
Sbjct: 446 GQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGL 491
>gi|149999378 inverted formin 2 isoform 2 [Homo sapiens]
Length = 1240
Score = 101 bits (251), Expect = 2e-21
Identities = 60/132 (45%), Positives = 67/132 (50%), Gaps = 26/132 (19%)
Query: 272 LRRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPP------SRAPTAAPPPP 325
L +QA PPPP PPPP P +S PPPP PPPPP PTA PPPP
Sbjct: 414 LEQQASTPPPP-----PPPPLLPGSSAEPPPP------PPPPPLPSVGAKALPTAPPPPP 462
Query: 326 PP-----SRPSVAVPPPPPN--RMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPP 378
P + P+ +PPP P PPPPP LP PPPPPP + G+G PPPPPP
Sbjct: 463 LPGLGAMAPPAPPLPPPLPGSCEFLPPPPPPLPGL--GCPPPPPPLLPGMGWGPPPPPPP 520
Query: 379 PPPPPGPPPPPG 390
P PP G
Sbjct: 521 LLPCTCSPPVAG 532
Score = 96.3 bits (238), Expect = 6e-20
Identities = 62/160 (38%), Positives = 75/160 (46%), Gaps = 24/160 (15%)
Query: 267 AVKNELRRQAPPPPPPSRGGPPPPPPPP-----HNSGPPPPPARGRGAPPPPPSRAPTAA 321
A + + + P + PPPPPPP ++ PPPPP PPP PS A
Sbjct: 400 AQSESILKVSQPRALEQQASTPPPPPPPPLLPGSSAEPPPPP-----PPPPLPSVGAKAL 454
Query: 322 P-PPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPP 380
P PPPP P + PP PP PP LP S PPPPPP + G+G PPPPPP
Sbjct: 455 PTAPPPPPLPGLGAMAPPA----PPLPPPLPGSCEFLPPPPPP-LPGLG--CPPPPPPLL 507
Query: 381 P----PPGPPPPPGLPSDGDHQVPTTAGNKAALLDQIREG 416
P P PPPPP LP P G + ++ Q+ G
Sbjct: 508 PGMGWGPPPPPPPLLPC--TCSPPVAGGMEEVIVAQVDHG 545
Score = 73.9 bits (180), Expect = 3e-13
Identities = 47/119 (39%), Positives = 53/119 (44%), Gaps = 17/119 (14%)
Query: 284 RGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMY 343
RG P P S PA P +++ + P + A PPPP
Sbjct: 369 RGSSPQNTTTPKPSVEGQQPAAAAACEPVDHAQSESILKVSQPRALEQQASTPPPP---- 424
Query: 344 PPPPPALP-SSAPSGPPPPPPSVLGVG----PVAPPPPP-------PPPPPPGPPPPPG 390
PPPP LP SSA PPPPPP + VG P APPPPP PP PP PPP PG
Sbjct: 425 -PPPPLLPGSSAEPPPPPPPPPLPSVGAKALPTAPPPPPLPGLGAMAPPAPPLPPPLPG 482
Score = 59.7 bits (143), Expect = 6e-09
Identities = 38/110 (34%), Positives = 44/110 (40%), Gaps = 23/110 (20%)
Query: 294 PHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSS 353
P N+ P P G+ P+ A P S + V P AL
Sbjct: 373 PQNTTTPKPSVEGQ-----QPAAAAACEPVDHAQSESILKVSQPR----------ALEQQ 417
Query: 354 APSGPPPPPPSVLGVGPVAPPPPPPPPPPPG--------PPPPPGLPSDG 395
A + PPPPPP +L PPPPPPPPP P PPPP LP G
Sbjct: 418 ASTPPPPPPPPLLPGSSAEPPPPPPPPPLPSVGAKALPTAPPPPPLPGLG 467
>gi|149999380 inverted formin 2 isoform 1 [Homo sapiens]
Length = 1249
Score = 101 bits (251), Expect = 2e-21
Identities = 60/132 (45%), Positives = 67/132 (50%), Gaps = 26/132 (19%)
Query: 272 LRRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPP------SRAPTAAPPPP 325
L +QA PPPP PPPP P +S PPPP PPPPP PTA PPPP
Sbjct: 414 LEQQASTPPPP-----PPPPLLPGSSAEPPPP------PPPPPLPSVGAKALPTAPPPPP 462
Query: 326 PP-----SRPSVAVPPPPPN--RMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPP 378
P + P+ +PPP P PPPPP LP PPPPPP + G+G PPPPPP
Sbjct: 463 LPGLGAMAPPAPPLPPPLPGSCEFLPPPPPPLPGL--GCPPPPPPLLPGMGWGPPPPPPP 520
Query: 379 PPPPPGPPPPPG 390
P PP G
Sbjct: 521 LLPCTCSPPVAG 532
Score = 96.3 bits (238), Expect = 6e-20
Identities = 62/160 (38%), Positives = 75/160 (46%), Gaps = 24/160 (15%)
Query: 267 AVKNELRRQAPPPPPPSRGGPPPPPPPP-----HNSGPPPPPARGRGAPPPPPSRAPTAA 321
A + + + P + PPPPPPP ++ PPPPP PPP PS A
Sbjct: 400 AQSESILKVSQPRALEQQASTPPPPPPPPLLPGSSAEPPPPP-----PPPPLPSVGAKAL 454
Query: 322 P-PPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPP 380
P PPPP P + PP PP PP LP S PPPPPP + G+G PPPPPP
Sbjct: 455 PTAPPPPPLPGLGAMAPPA----PPLPPPLPGSCEFLPPPPPP-LPGLG--CPPPPPPLL 507
Query: 381 P----PPGPPPPPGLPSDGDHQVPTTAGNKAALLDQIREG 416
P P PPPPP LP P G + ++ Q+ G
Sbjct: 508 PGMGWGPPPPPPPLLPC--TCSPPVAGGMEEVIVAQVDHG 545
Score = 73.9 bits (180), Expect = 3e-13
Identities = 47/119 (39%), Positives = 53/119 (44%), Gaps = 17/119 (14%)
Query: 284 RGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMY 343
RG P P S PA P +++ + P + A PPPP
Sbjct: 369 RGSSPQNTTTPKPSVEGQQPAAAAACEPVDHAQSESILKVSQPRALEQQASTPPPP---- 424
Query: 344 PPPPPALP-SSAPSGPPPPPPSVLGVG----PVAPPPPP-------PPPPPPGPPPPPG 390
PPPP LP SSA PPPPPP + VG P APPPPP PP PP PPP PG
Sbjct: 425 -PPPPLLPGSSAEPPPPPPPPPLPSVGAKALPTAPPPPPLPGLGAMAPPAPPLPPPLPG 482
Score = 59.7 bits (143), Expect = 6e-09
Identities = 38/110 (34%), Positives = 44/110 (40%), Gaps = 23/110 (20%)
Query: 294 PHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSS 353
P N+ P P G+ P+ A P S + V P AL
Sbjct: 373 PQNTTTPKPSVEGQ-----QPAAAAACEPVDHAQSESILKVSQPR----------ALEQQ 417
Query: 354 APSGPPPPPPSVLGVGPVAPPPPPPPPPPPG--------PPPPPGLPSDG 395
A + PPPPPP +L PPPPPPPPP P PPPP LP G
Sbjct: 418 ASTPPPPPPPPLLPGSSAEPPPPPPPPPLPSVGAKALPTAPPPPPLPGLG 467
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 100 bits (249), Expect = 3e-21
Identities = 64/163 (39%), Positives = 72/163 (44%), Gaps = 39/163 (23%)
Query: 275 QAPPPPPPSRGGPPP--------PPPPPHNSGPPPPPARGRG--APP-----PPPSRAPT 319
Q PPPPP GPPP PPPP GPPP + R +PP PPP
Sbjct: 69 QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQ 128
Query: 320 AAPPPPPPSRPSVAVP--------PPPPNRMYPPPPP----ALPSSAPSGPPPPPPSVLG 367
PPPPP +P P PPPP + PPP + S +P G P PP G
Sbjct: 129 PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGG 188
Query: 368 VGPVAPPPPP----PPPP-----PPGPPP---PPGLPSDGDHQ 398
P PPPPP PPP P GPPP P G P GD++
Sbjct: 189 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNK 231
Score = 98.2 bits (243), Expect = 2e-20
Identities = 64/176 (36%), Positives = 69/176 (39%), Gaps = 54/176 (30%)
Query: 275 QAPPPPPPSRGGPPP--------PPPPPHNSGPPP-----------PPARGRGAPP---- 311
Q PPPPP GPPP PPPP GPPP PP + +G PP
Sbjct: 130 QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGN 189
Query: 312 -----PPPSRAPTAAPP--------PPPPSRPSVAVPPP-----------PPNRMYPPPP 347
PPP P PP PPPP +P PPP PP + PPP
Sbjct: 190 QPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG--PPPQGDNKSQSARSPPGKPQGPPP 247
Query: 348 PALPSSAPSGPPPPPPSVLGVGPVA---PPPPPPPPPPPGPPPPPGLPSDGDHQVP 400
+ P GPPPPP G P P PPPP P GPPP G S P
Sbjct: 248 QG--GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPP 301
Score = 97.4 bits (241), Expect = 3e-20
Identities = 61/155 (39%), Positives = 67/155 (43%), Gaps = 38/155 (24%)
Query: 275 QAPPPPPPSRGGPPP--------PPPPPHNSGPPP-----------PPARGRGAPPPPPS 315
Q PPPPP GPPP PPPP GPPP PP + +G PPP
Sbjct: 192 QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQG-PPPQGG 250
Query: 316 RAPTAAPPPP------PPSRPSVAVPPPPPNRMYPPPPP----ALPSSAPSGPPPPPPSV 365
P PPPP PP + PPPP + PPP + S +P G P PP
Sbjct: 251 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQ 310
Query: 366 LGVGPVAPPPPP----PPPP----PPGPPPPPGLP 392
G P PPPPP PPP P PPPPG P
Sbjct: 311 GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP 345
Score = 93.2 bits (230), Expect = 5e-19
Identities = 58/155 (37%), Positives = 63/155 (40%), Gaps = 34/155 (21%)
Query: 275 QAPPPPPPSRGGPPP--------PPPPPHNSGPPPP---PARGRGAPP-----PPPSRAP 318
Q PPPPP GPPP PPPP GPPP +R +PP PPP
Sbjct: 254 QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGN 313
Query: 319 TAAPPPPPPSRPSVAVP--------PPPPNRMYPPPPPALPSS----APSGPPPPPPSVL 366
PPPPP +P P PPPP + PPP S +P G P PP
Sbjct: 314 QPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQE 373
Query: 367 GVGPVAPPPPP------PPPPPPGPPPPPGLPSDG 395
G P PPPP P PP G P P P G
Sbjct: 374 GNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQG 408
Score = 92.4 bits (228), Expect = 8e-19
Identities = 57/145 (39%), Positives = 61/145 (42%), Gaps = 31/145 (21%)
Query: 276 APPPPPPSRGGPPPPP-----PPPHN----SGPPPPPARGRGAPPPPPSRAPTAAPPP-- 324
APP GPP PP PPP GPPPPP + +G PPP P PPP
Sbjct: 39 APPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQG-PPPQGGNKPQGPPPPGK 97
Query: 325 ---PPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVA---PPPPPP 378
PPP P PP + PPP + P GPPPPP G P P PPP
Sbjct: 98 PQGPPPQGDKSRSPRSPPGKPQGPPPQG--GNQPQGPPPPPGKPQGPPPQGGNKPQGPPP 155
Query: 379 PPPPPGPPP-----------PPGLP 392
P P GPPP PPG P
Sbjct: 156 PGKPQGPPPQGDNKSRSSRSPPGKP 180
Score = 90.5 bits (223), Expect = 3e-18
Identities = 56/141 (39%), Positives = 62/141 (43%), Gaps = 26/141 (18%)
Query: 277 PPPPPPSRGGPP--PPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAV 334
P PP G P PP PP GPPP PPPPP + P PPP +
Sbjct: 36 PQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGK-----PQGPPPQGGNKPQ 90
Query: 335 PPPPPNRMYPPPPPALPSSAPSGPP-----PPPPSVLGVGPVAPPPPP-----PPP---- 380
PPPP + PPP S +P PP PPP G P PPPPP PPP
Sbjct: 91 GPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQG--GNQPQGPPPPPGKPQGPPPQGGN 148
Query: 381 PPPGPPP---PPGLPSDGDHQ 398
P GPPP P G P GD++
Sbjct: 149 KPQGPPPPGKPQGPPPQGDNK 169
Score = 90.1 bits (222), Expect = 4e-18
Identities = 62/162 (38%), Positives = 67/162 (41%), Gaps = 38/162 (23%)
Query: 277 PPPPPPSRGGPPPPPPPPHN--SGPPP--------PPARGRGAPPPP-------PSRAPT 319
P PPP G P PPPP GPPP PP G+ PPP SR+P
Sbjct: 118 PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPP 177
Query: 320 AAPPPPPPSRPSVAV-PPPPPNRMYPPPPPALPSSAPSGPPPP-----PP------SVLG 367
P PPP + PPPPP + PPP + P GPPPP PP S
Sbjct: 178 GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG--GNKPQGPPPPGKPQGPPPQGDNKSQSA 235
Query: 368 VGPVAPPPPPPPP---PPPGPPPPPGLPSDGDHQVPTTAGNK 406
P P PPP P GPPPPPG P P GNK
Sbjct: 236 RSPPGKPQGPPPQGGNQPQGPPPPPGKPQG----PPPQGGNK 273
Score = 86.7 bits (213), Expect = 5e-17
Identities = 59/171 (34%), Positives = 64/171 (37%), Gaps = 54/171 (31%)
Query: 277 PPPPPPSRGGPPPPPPPPHN--SGP----------PPPPARGRGAPP------------- 311
P PPP G P PPPP GP PPPP + +G PP
Sbjct: 242 PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPP 301
Query: 312 -----PPPSRAPTAAPPPPPPSRPSVAVP--------PPPPNRMYPPPPPALPSS----A 354
PPP PPPPP +P P PPPP + PPP S +
Sbjct: 302 GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARS 361
Query: 355 PSGPPPPPPSVLGVGPVAPPPP----------PPPPPPPGPPPPP--GLPS 393
P G P PP G P PPPP PP P GPP PP G PS
Sbjct: 362 PPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPS 412
Score = 62.4 bits (150), Expect = 9e-10
Identities = 42/115 (36%), Positives = 46/115 (40%), Gaps = 26/115 (22%)
Query: 313 PPSRAPTAAPPPPPPSRPSVAVPPPPPNRMY-PPPPPALP-------SSAPSGPP----- 359
PP PP PP +P PP N+ PPPPP P + P GPP
Sbjct: 40 PPQGGNKPQGPPSPPGKPQ-GPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP 98
Query: 360 --PPPPSVLGVGPVAPPPPPPPPP------PPGPPPPPGLPSDGDHQVPTTAGNK 406
PPP P +PP P PP P GPPPPPG P P GNK
Sbjct: 99 QGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQG----PPPQGGNK 149
Score = 50.1 bits (118), Expect = 5e-06
Identities = 29/83 (34%), Positives = 33/83 (39%), Gaps = 14/83 (16%)
Query: 325 PPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPG 384
PP PP PP + PPP + P GPPPPP P PPP G
Sbjct: 40 PPQGGNKPQGPPSPPGKPQGPPPQG--GNQPQGPPPPPGK------------PQGPPPQG 85
Query: 385 PPPPPGLPSDGDHQVPTTAGNKA 407
P G P G Q P G+K+
Sbjct: 86 GNKPQGPPPPGKPQGPPPQGDKS 108
Score = 43.1 bits (100), Expect = 6e-04
Identities = 28/68 (41%), Positives = 30/68 (44%), Gaps = 17/68 (25%)
Query: 348 PALPSSAPSGPPPPPPSVLGVGPVAPPPPP-----PPP----PPPGPPPPPGLPSDGDHQ 398
P+L + P G PP G P PP PP PPP P GPPPPPG P
Sbjct: 29 PSLIAGNPQGAPPQG----GNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQG---- 80
Query: 399 VPTTAGNK 406
P GNK
Sbjct: 81 PPPQGGNK 88
>gi|157168329 formin 1 [Homo sapiens]
Length = 1196
Score = 100 bits (248), Expect = 4e-21
Identities = 52/105 (49%), Positives = 57/105 (54%), Gaps = 18/105 (17%)
Query: 291 PPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPAL 350
PPPP + PPPP G G+ P P P +A PP +PPPPP PPPP
Sbjct: 646 PPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPP---------LPPPPP-----PPPPLP 691
Query: 351 PSSAPSGPPPPPPSVLGVGPVAPPP--PPPPPPPPG--PPPPPGL 391
P S+ PPPPPP L P P P PPP PPPPG PPPPPGL
Sbjct: 692 PPSSAGPPPPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPPPGL 736
Score = 87.0 bits (214), Expect = 4e-17
Identities = 50/114 (43%), Positives = 54/114 (47%), Gaps = 20/114 (17%)
Query: 276 APPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVP 335
APP PP S G P PPPPPP PPP P PPPPP PPPP P+ P+
Sbjct: 668 APPMPPVSAGPPLPPPPPP----PPPLPPPSSAGPPPPP-------PPPPLPNSPA---- 712
Query: 336 PPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGPPPPP 389
PPN PPP P P A PPPPP G+G + P P P P P
Sbjct: 713 --PPNPGGPPPAPPPPGLA---PPPPPGLFFGLGSSSSQCPRKPAIEPSCPMKP 761
Score = 79.3 bits (194), Expect = 7e-15
Identities = 48/104 (46%), Positives = 50/104 (48%), Gaps = 30/104 (28%)
Query: 300 PPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPP 359
PPPPA PPPPP + + P PP P A PP PP PPPPP PP
Sbjct: 646 PPPPA---SIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPP----PPPPP---------PP 689
Query: 360 PPPPSVLGVGPVAPPPPPPPPPP----PGPP----PPPGLPSDG 395
PPPS G PPPPPPPPP P PP PPP P G
Sbjct: 690 LPPPSSAG------PPPPPPPPPLPNSPAPPNPGGPPPAPPPPG 727
Score = 73.2 bits (178), Expect = 5e-13
Identities = 38/82 (46%), Positives = 42/82 (51%), Gaps = 8/82 (9%)
Query: 328 SRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPP---- 383
S A+PPPP + PPPP LPS S P PP + GP PPPPPPPPP P
Sbjct: 639 SNQQKALPPPPASI---PPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSS 695
Query: 384 -GPPPPPGLPSDGDHQVPTTAG 404
GPPPPP P + P G
Sbjct: 696 AGPPPPPPPPPLPNSPAPPNPG 717
Score = 65.9 bits (159), Expect = 8e-11
Identities = 37/80 (46%), Positives = 41/80 (51%), Gaps = 21/80 (26%)
Query: 321 APPPPPPSRPSVAVPPPPP-----NRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPP 375
A PPPP S +PPPPP + P PP S+ P PPPPPP PPP
Sbjct: 644 ALPPPPAS-----IPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPP---------PPP 689
Query: 376 PPPPPP--PPGPPPPPGLPS 393
PPP PP PPPPP LP+
Sbjct: 690 LPPPSSAGPPPPPPPPPLPN 709
Score = 35.8 bits (81), Expect = 0.094
Identities = 26/78 (33%), Positives = 31/78 (39%), Gaps = 32/78 (41%)
Query: 346 PPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPP-------PPPPGP------------P 386
P + S+ PPPP S+ PPPPP P P PP P P
Sbjct: 633 PMEGMASNQQKALPPPPASI-------PPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPP 685
Query: 387 PPPGLPSDGDHQVPTTAG 404
PPP LP P++AG
Sbjct: 686 PPPPLPP------PSSAG 697
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 99.8 bits (247), Expect = 5e-21
Identities = 61/146 (41%), Positives = 65/146 (44%), Gaps = 21/146 (14%)
Query: 278 PPPPPSRGGPPPPPP--PPHNSGPPPPPARGRGAPPP---PPSRAPTAAPPPP------- 325
PPPP G PP PP PP GPP PP G+ PPP PP+R PPPP
Sbjct: 226 PPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGD--RPPPPVLFPGQP 283
Query: 326 ---PPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGP----PPPPPSVLGVGPVAPPPPPP 378
PP P PPPP PPP P P P P PP PP LG PPP
Sbjct: 284 FGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHL 343
Query: 379 PPPPPGPPPPPGLPSDGDHQVPTTAG 404
P PPPG PPP + PT +G
Sbjct: 344 PGPPPGAPPPAPHVNPAFFPPPTNSG 369
Score = 99.4 bits (246), Expect = 7e-21
Identities = 59/122 (48%), Positives = 60/122 (49%), Gaps = 28/122 (22%)
Query: 279 PPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPP- 337
P P GGPPPP P PP PP PP PP PP PPP P +PPP
Sbjct: 218 PGPAGPGGPPPPFPAGQT--PPRPPL----GPPGPPG------PPGPPP--PGQVLPPPL 263
Query: 338 --PPNRMYPPPPPALPSSAPSGPPP-------PPPSVLGVGPVAPPPPPPPPPPPGPPPP 388
PPNR PPPP L P G PP PPP V G G PPP PPPP GPPPP
Sbjct: 264 AGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYG----PPPGPPPPQQGPPPP 319
Query: 389 PG 390
PG
Sbjct: 320 PG 321
Score = 91.7 bits (226), Expect = 1e-18
Identities = 59/141 (41%), Positives = 64/141 (45%), Gaps = 35/141 (24%)
Query: 275 QAPPPP---PPSRGGPPPPP---------PPPHNSGPP--PPPARGRGAPPPPPSRAPTA 320
Q PPP PP+RG PPPP PP PP PPP G G PP PP P
Sbjct: 257 QVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPP--PPQQ 314
Query: 321 APPPPPPSRPSVAVPPPPPNRMYPP----PPPALPSSAPSGPPP---------PPPSVLG 367
PPPPP PP PP + PP PPP LP P PPP PPP+ G
Sbjct: 315 GPPPPPG-----PFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSG 369
Query: 368 VGPVAPPPPPPPPPPPGPPPP 388
+ P + PPP P G PPP
Sbjct: 370 M-PTSDSRGPPPTDPYGRPPP 389
Score = 77.4 bits (189), Expect = 3e-14
Identities = 50/128 (39%), Positives = 53/128 (41%), Gaps = 28/128 (21%)
Query: 277 PPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPP----PPPSRP-- 330
P PPPP G PPP PPP GPPPPP PP P T APPP PPP P
Sbjct: 294 PGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPP 353
Query: 331 ----SVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGPP 386
+ A PPP N +P+S GPPP P PPP G
Sbjct: 354 APHVNPAFFPPPTNS-------GMPTSDSRGPPP-----------TDPYGRPPPYDRGDY 395
Query: 387 PPPGLPSD 394
PPG D
Sbjct: 396 GPPGREMD 403
Score = 76.3 bits (186), Expect = 6e-14
Identities = 52/125 (41%), Positives = 56/125 (44%), Gaps = 25/125 (20%)
Query: 291 PPPPHNSGPPPPPARGRGAPP---PPPSRAP-TAAPPPPPPSRPSVAVPPPPPNRMYPPP 346
PP + P RGRG P P R P A P PPP P+ PP PP + PP
Sbjct: 188 PPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPP--LGPPG 245
Query: 347 PPALPSSAPSG---PPP----------PPPSVL------GVGPVAPPPPPPPPPPPGPPP 387
PP P P G PPP PPP VL G P+ P PP PPPP PG P
Sbjct: 246 PPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGP 305
Query: 388 PPGLP 392
PPG P
Sbjct: 306 PPGPP 310
Score = 66.2 bits (160), Expect = 6e-11
Identities = 40/94 (42%), Positives = 42/94 (44%), Gaps = 16/94 (17%)
Query: 274 RQAPPPP----PPSRGGPPPPP----PPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPP 325
+Q PPPP PP GP PP PPPH GPPP GAPPP P P PPP
Sbjct: 313 QQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPP------GAPPPAPHVNPAFFPPPT 366
Query: 326 PPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPP 359
P+ PPP Y PPP GPP
Sbjct: 367 NSGMPTSDSRGPPPTDPYGRPPPY--DRGDYGPP 398
Score = 51.2 bits (121), Expect = 2e-06
Identities = 36/99 (36%), Positives = 39/99 (39%), Gaps = 17/99 (17%)
Query: 306 GRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSV 365
G+ PP SRA P R P P P P + P GPPPP P+
Sbjct: 184 GKAGPPGGSSRAAF-----PQGGRGRGRFPGAVPGGDRFPGP-----AGPGGPPPPFPA- 232
Query: 366 LGVGPVAPPPPPPPPPPPGPPPPPGLPSDGDHQVPTTAG 404
PP PP PPGPP PPG P G P AG
Sbjct: 233 ------GQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAG 265
Score = 40.4 bits (93), Expect = 0.004
Identities = 29/71 (40%), Positives = 29/71 (40%), Gaps = 23/71 (32%)
Query: 276 APPP--PPPSRGGPPPPP-------PPPHNSG--------PPP------PPARGRGAPPP 312
APPP P P G PPP P PPP NSG PPP PP RG P
Sbjct: 338 APPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGP 397
Query: 313 PPSRAPTAAPP 323
P TA P
Sbjct: 398 PGREMDTARTP 408
Score = 32.0 bits (71), Expect = 1.4
Identities = 22/63 (34%), Positives = 25/63 (39%), Gaps = 21/63 (33%)
Query: 276 APPP---------PPPSRGGPP------PPP------PPPHNSGPPPPPARGRGAPPPPP 314
APPP PPP+ G P PPP PPP++ G PP R P
Sbjct: 350 APPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREMDTARTPL 409
Query: 315 SRA 317
S A
Sbjct: 410 SEA 412
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 99.8 bits (247), Expect = 5e-21
Identities = 59/142 (41%), Positives = 73/142 (51%), Gaps = 23/142 (16%)
Query: 264 GVEAVKNELRRQAPP--PPPPSRGGPPPPPPPPH--NSGPPPPPARGRGAPPPPPSRAPT 319
G +++++ ++ + P PP+ G P P PH PPPPP PPPP S P
Sbjct: 443 GYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPV-----PPPPASFPPP 497
Query: 320 AAPPPPPPSRPSVAVPPPPP--NRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPP 377
A PPP P PPPPP N +PPPPP LP + PP PP LG+ P + PPP
Sbjct: 498 AIPPPTP------GYPPPPPTYNPNFPPPPPRLPPT--HAVPPHPPPGLGLPPASYPPPA 549
Query: 378 PPP----PPPGPPPPPGLPSDG 395
PP P P P PPPG+P G
Sbjct: 550 VPPGGQPPVPPPIPPPGMPPVG 571
Score = 95.5 bits (236), Expect = 1e-19
Identities = 55/114 (48%), Positives = 60/114 (52%), Gaps = 19/114 (16%)
Query: 278 PPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPP 337
PP PP PPP PPPP + PP P G PPPPP+ P PPPPP P+ AVPP
Sbjct: 479 PPNPP----PPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPN-FPPPPPRLPPTHAVPP- 532
Query: 338 PPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGPPPPPGL 391
+PPP LP P+ PPP V P PP PPP PPPG PP GL
Sbjct: 533 -----HPPPGLGLP---PASYPPP-----AVPPGGQPPVPPPIPPPGMPPVGGL 573
Score = 85.1 bits (209), Expect = 1e-16
Identities = 57/162 (35%), Positives = 63/162 (38%), Gaps = 45/162 (27%)
Query: 280 PPPSRGGPPPPPPP-PHNSGPPPPPARGRGAP----------------------PPPPSR 316
PPP+ P PPP PH PPPP + G P +
Sbjct: 402 PPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGAL 461
Query: 317 APTAAPPPPPPSRPSVAVPPPPPNRMYPPP----PPALPSSAPSGPPPPPPSVLGVGPVA 372
P PP P P V P PPP + PPP PPA+P P PPPPP P
Sbjct: 462 PPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPT----YNPNF 517
Query: 373 PPPPPPPPP----PPGPPP----------PPGLPSDGDHQVP 400
PPPPP PP PP PPP PP +P G VP
Sbjct: 518 PPPPPRLPPTHAVPPHPPPGLGLPPASYPPPAVPPGGQPPVP 559
Score = 80.5 bits (197), Expect = 3e-15
Identities = 57/167 (34%), Positives = 67/167 (40%), Gaps = 35/167 (20%)
Query: 261 KTGGVEAVKNELRRQAPPPP--PPSRGGPPPPPP--PPHNSGPPPPPARGRGAPPPPPSR 316
K V + K E + PPPP P PP PP PP + PP A G PP P
Sbjct: 334 KRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDA 393
Query: 317 APTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPA------------------------LPS 352
PPP+ P+ PPP PPPPP+ + +
Sbjct: 394 TDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKT 453
Query: 353 SAPS-GPPPP---PPSVLGVGPVAPPPPPPPPPPPGPP---PPPGLP 392
PS G PP PP+ L P PP PPPPP P PP PPP +P
Sbjct: 454 EGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIP 500
Score = 61.2 bits (147), Expect = 2e-09
Identities = 46/152 (30%), Positives = 55/152 (36%), Gaps = 38/152 (25%)
Query: 275 QAPPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAP--PPPPPSRP-- 330
Q PP P+ P P S P P + + P + P P P P PS P
Sbjct: 274 QQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQ-KDPQQPAQQQQPAQQPKKPSPQPSSPRQ 332
Query: 331 ---SVAVPPPPPNRMYPPPPPALPSSAPSGPPPP---------PPSVLGVGPVAPP---- 374
+V V P N+ PPPP +P + PP P PP +G PP
Sbjct: 333 VKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVD 392
Query: 375 ---------PPP--------PPPPPPGPPPPP 389
PPP PPP P PPPPP
Sbjct: 393 ATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPP 424
Score = 58.2 bits (139), Expect = 2e-08
Identities = 35/118 (29%), Positives = 42/118 (35%)
Query: 275 QAPPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAV 334
Q P P++ P P + P P R P A PPPP +
Sbjct: 303 QQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTH 362
Query: 335 PPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGPPPPPGLP 392
PP PP P P L ++ PP P + V PPP P P PPP P P
Sbjct: 363 PPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRP 420
Score = 57.0 bits (136), Expect = 4e-08
Identities = 42/125 (33%), Positives = 48/125 (38%), Gaps = 23/125 (18%)
Query: 274 RQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAP---TAAPPPPPPSRP 330
+Q P P + P P P P A PPP + P T PP PP
Sbjct: 312 QQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAH-- 369
Query: 331 SVAVPPPPPNRMYPPPPPALPSSAPSGPPP---------PPPSVLGVGPVAPPPPPPPPP 381
PPP+R PP AL + P GP PPP+ PV PPP P P
Sbjct: 370 ------PPPDRK-PPLAAALGEAEPPGPVDATDLPKVQIPPPA--HPAPVHQPPPLPHRP 420
Query: 382 PPGPP 386
PP PP
Sbjct: 421 PPPPP 425
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 97.8 bits (242), Expect = 2e-20
Identities = 62/147 (42%), Positives = 71/147 (48%), Gaps = 19/147 (12%)
Query: 273 RRQAPPP--PPPSRGGP--PPPPPPPHNSGPPPPP---------ARGRGAPPPPPSRAPT 319
++Q PPP PPP + P PPP P PH PPPP A+G G P P AP
Sbjct: 68 QQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPG-PAPGVGSAPP 126
Query: 320 AAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPP 379
A+ PP + P+ PP P PPPA+ +SAP G PPP P GV P PP P
Sbjct: 127 ASSSAPPATPPTSGAPPGSGPGPTPTPPPAV-TSAPPGAPPPTPPSSGV-PTTPPQAGGP 184
Query: 380 PPPPGPPPPPGLPSDGDHQVPTTAGNK 406
PPPP P PG G Q P G K
Sbjct: 185 PPPPAAVPGPG---PGPKQGPGPGGPK 208
Score = 94.4 bits (233), Expect = 2e-19
Identities = 65/163 (39%), Positives = 71/163 (43%), Gaps = 33/163 (20%)
Query: 275 QAPPPPPPSRGGPPP---------PPPPPHNSGPP-----PPPARGRGAPPPPPSRAPTA 320
Q PPP P PPP PPPPP +S P P PA G G+ PP S AP A
Sbjct: 75 QQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPA 134
Query: 321 APPP---PPPSRPSVAVPPPPPNRMYPP--PPPALPSSA------PSGPPPPPPSVL--- 366
PP PP S P PPP PP PPP PSS +G PPPPP+ +
Sbjct: 135 TPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGP 194
Query: 367 GVGPVAPPPPPPP-----PPPPGPPPPPGLPSDGDHQVPTTAG 404
G GP P P P P P P PGL + G H P G
Sbjct: 195 GPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPPHRG 237
Score = 73.2 bits (178), Expect = 5e-13
Identities = 56/158 (35%), Positives = 62/158 (39%), Gaps = 33/158 (20%)
Query: 273 RRQAPPPPPPSRG------GPPPPP-----PPPHNSGPPP-------PPARGRGAPPPPP 314
++Q PPPPP GP P P PP +S PP PP G G P PP
Sbjct: 95 QQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPP 154
Query: 315 SRAPTAAPPPPPPSRPSVAVP--------PPPPNRMYPPPPPALPSSAPSGPPPPPPSVL 366
+A P PPP+ PS VP PPPP P P P P P GP P +
Sbjct: 155 PAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPG-PKQGP-GPGGPKGGKM 212
Query: 367 GVGPVAPPPPPPPPPPPGPPPPP----GLPSDGDHQVP 400
GP P P P G P PP G P G P
Sbjct: 213 PGGP-KPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHP 249
Score = 43.1 bits (100), Expect = 6e-04
Identities = 29/89 (32%), Positives = 32/89 (35%), Gaps = 4/89 (4%)
Query: 275 QAPPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAV 334
QA PPPP P P P P GP P G+ P P P + P P P
Sbjct: 180 QAGGPPPPPAAVPGPGPGPKQGPGPGGPKG-GKMPGGPKPGGGPGLSTPGGHPKPPHRGG 238
Query: 335 PPPPPNRMYPPPPPALPSSAPSGPPPPPP 363
P R + PP GPPP P
Sbjct: 239 GEPRGGRQHHPP---YHQQHHQGPPPGGP 264
>gi|18959210 WIRE protein [Homo sapiens]
Length = 440
Score = 97.4 bits (241), Expect = 3e-20
Identities = 71/208 (34%), Positives = 76/208 (36%), Gaps = 85/208 (40%)
Query: 276 APPPPPPSRGGPPPPPPPPHNSG-----------PPPPPAR---GRGAPPPPPSRAPTAA 321
APPPPPP R PP P P +S PP P R GR PP PP P +
Sbjct: 176 APPPPPPGRRANAPPTPLPMHSSKAPAYNREKPLPPTPGQRLHPGREGPPAPPPVKPPPS 235
Query: 322 P-------------PPPPPSRPSVAVP--------------------------------- 335
P PPPPP R VP
Sbjct: 236 PVNIRTGPSGQSLAPPPPPYRQPPGVPNGPSSPTNESAPELPQRHNSLHRKTPGPVRGLA 295
Query: 336 PPPPNRMYP------PPPPAL-PSSAPSGPPPPPPSVLGVGPVAPPPPPP---------- 378
PPPP P PPPPA P S + PPPPPP + APPPPPP
Sbjct: 296 PPPPTSASPSLLSNRPPPPARDPPSRGAAPPPPPPVIRNGARDAPPPPPPYRMHGSEPPS 355
Query: 379 ---PPPPP-----GPPPPPGLPSDGDHQ 398
PPPPP GPPPPP P H+
Sbjct: 356 RGKPPPPPSRTPAGPPPPPPPPLRNGHR 383
Score = 83.2 bits (204), Expect = 5e-16
Identities = 51/110 (46%), Positives = 58/110 (52%), Gaps = 19/110 (17%)
Query: 270 NELRRQAPPPPPPSRGGPPPPP----PPPHNSGPPPP----PARGRGAPPPPP--SRAPT 319
N L R+ P P RG PPPP P ++ PPPP P+RG PPPPP
Sbjct: 281 NSLHRKTPGPV---RGLAPPPPTSASPSLLSNRPPPPARDPPSRGAAPPPPPPVIRNGAR 337
Query: 320 AAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVG 369
APPPPPP R + PP+R PPPP PS P+GPPPPPP L G
Sbjct: 338 DAPPPPPPYRMHGS---EPPSRGKPPPP---PSRTPAGPPPPPPPPLRNG 381
Score = 65.9 bits (159), Expect = 8e-11
Identities = 55/175 (31%), Positives = 64/175 (36%), Gaps = 43/175 (24%)
Query: 257 DFIEKTGGVEAVKNELRRQAPPPPPPSRGGPPPP------------------PPPPHNSG 298
D E G A++ R A P PP S P P P S
Sbjct: 102 DGSENLAGKPALQIPSSRAAAPRPPVSAASGRPQDDTDSSRASLPELPRMQRPSLPDLSR 161
Query: 299 PPPPPARGR----GAPPPPPSRAPTAAPPPPPPSRPSVA--------VPPPPPNRMYP-- 344
P + G APPPPP APP P P S A +PP P R++P
Sbjct: 162 PNTTSSTGMKHSSSAPPPPPPGRRANAPPTPLPMHSSKAPAYNREKPLPPTPGQRLHPGR 221
Query: 345 --PPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPP---PPGPPPPPGLPSD 394
PP P P PPP P + GP PPPPP PPG P P P++
Sbjct: 222 EGPPAP------PPVKPPPSPVNIRTGPSGQSLAPPPPPYRQPPGVPNGPSSPTN 270
Score = 52.0 bits (123), Expect = 1e-06
Identities = 37/100 (37%), Positives = 46/100 (46%), Gaps = 28/100 (28%)
Query: 374 PPPPPPPPPPGPPPPPGLPSDGDHQVPTTAGNKAALLDQIREGAQLKKVEQNSRPVSCSG 433
P PPPPPPPPGPPPPP HQ T E +L + EQ G
Sbjct: 2 PIPPPPPPPPGPPPPPTF-----HQANT-------------EQPKLSRDEQR-------G 36
Query: 434 RDALLDQIRQGIQLKSVADGQESTPP---TPAPTSGIVGA 470
R ALL I +G +LK V + + + P P +SG G+
Sbjct: 37 RGALLQDICKGTKLKKVTNINDRSAPILEKPKGSSGGYGS 76
Score = 50.1 bits (118), Expect = 5e-06
Identities = 36/110 (32%), Positives = 43/110 (39%), Gaps = 18/110 (16%)
Query: 268 VKNELRRQAPPPP--------PPSRGGPPPPP------PPPHNSGPPPPPARGRGAPPPP 313
++N R PPPP PPSRG PPPPP PPP PPPPP R
Sbjct: 332 IRNGARDAPPPPPPYRMHGSEPPSRGKPPPPPSRTPAGPPP----PPPPPLRNGHRDSIT 387
Query: 314 PSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPP 363
R+ P P P + + P+ + A G PP PP
Sbjct: 388 TVRSFLDDFESKYSFHPVEDFPAPEEYKHFQRIYPSKTNRAARGAPPLPP 437
Score = 36.6 bits (83), Expect = 0.055
Identities = 19/38 (50%), Positives = 20/38 (52%), Gaps = 7/38 (18%)
Query: 277 PPPPPPSRGGPPPPPPPPHNSGPPPP-----PARGRGA 309
PPPPPP G PPPPP H + P RGRGA
Sbjct: 4 PPPPPPPPG--PPPPPTFHQANTEQPKLSRDEQRGRGA 39
Score = 33.5 bits (75), Expect = 0.47
Identities = 12/16 (75%), Positives = 12/16 (75%)
Query: 288 PPPPPPPHNSGPPPPP 303
P PPPPP GPPPPP
Sbjct: 2 PIPPPPPPPPGPPPPP 17
Score = 30.8 bits (68), Expect = 3.0
Identities = 15/29 (51%), Positives = 16/29 (55%), Gaps = 12/29 (41%)
Query: 334 VPPPPPNRMYPPPPPALPSSAPSGPPPPP 362
+P PPP PPPPP GPPPPP
Sbjct: 1 MPIPPP----PPPPP--------GPPPPP 17
Score = 30.4 bits (67), Expect = 3.9
Identities = 13/29 (44%), Positives = 14/29 (48%), Gaps = 14/29 (48%)
Query: 287 PPPPPPPPHNSGPPPPPARGRGAPPPPPS 315
PPPPPPPP PPPPP+
Sbjct: 4 PPPPPPPP--------------GPPPPPT 18
Score = 29.6 bits (65), Expect = 6.7
Identities = 11/25 (44%), Positives = 13/25 (52%)
Query: 334 VPPPPPNRMYPPPPPALPSSAPSGP 358
+PPPPP PPPPP + P
Sbjct: 3 IPPPPPPPPGPPPPPTFHQANTEQP 27
Score = 29.3 bits (64), Expect = 8.8
Identities = 12/22 (54%), Positives = 12/22 (54%), Gaps = 6/22 (27%)
Query: 318 PTAAPPPPPPSRPSVAVPPPPP 339
P PPPPPP PPPPP
Sbjct: 2 PIPPPPPPPPG------PPPPP 17
>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
Length = 639
Score = 95.9 bits (237), Expect = 8e-20
Identities = 61/163 (37%), Positives = 68/163 (41%), Gaps = 55/163 (33%)
Query: 277 PPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPP---------------------- 314
PPPPPP G PPPPP SGP PP + + PPPPP
Sbjct: 479 PPPPPPPSGQPPPPP-----SGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTT 533
Query: 315 SRAPTAAPPPPPPSRPSVAVPPPPPN-----RMYPPPP---PALPSSAPSGPPPPPPSVL 366
+ A T + PP + + A P P M P PP P LP AP PPPPPP
Sbjct: 534 TSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSA 593
Query: 367 GVGPVAPPPPPPP-----------------PP---PPGPPPPP 389
G+ PPPPPPP PP PP PPPPP
Sbjct: 594 GMMYAPPPPPPPPMDPSNFVTMMGMGVAGMPPFGMPPAPPPPP 636
Score = 92.0 bits (227), Expect = 1e-18
Identities = 59/147 (40%), Positives = 67/147 (45%), Gaps = 38/147 (25%)
Query: 280 PPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPP 339
PPP G PPPPPPP SG PPPP G P PP + PPPPPP S+A P P
Sbjct: 471 PPPPMGMMPPPPPPP--SGQPPPPPSG----PLPPWQQQQQQPPPPPPPSSSMASSTPLP 524
Query: 340 NRM-------------YPP--PPPALPSSAPSGP---------PPPPPSVLGVGPVAPPP 375
+ PP A +++P P P PP + P APPP
Sbjct: 525 WQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPP 584
Query: 376 PPPPPP--------PPGPPPPPGLPSD 394
PPPPPP PP PPPPP PS+
Sbjct: 585 PPPPPPGSAGMMYAPPPPPPPPMDPSN 611
Score = 79.7 bits (195), Expect = 6e-15
Identities = 59/175 (33%), Positives = 66/175 (37%), Gaps = 49/175 (28%)
Query: 279 PPPPSRGGPPPP----PPPPHNSGPPPPPA---------------RGRGAPPPPPSRAPT 319
PPPP PPPP P PP + GPPP +G+G PPPP
Sbjct: 420 PPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMP 479
Query: 320 AAPPPP---PPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPP--------------- 361
PPPP PP PS +PP + PPPPP SS S P P
Sbjct: 480 PPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTG 539
Query: 362 --PP-----SVLGVGPVAP-----PPPPPPPPPPGPPPPPGLPSDGDHQVPTTAG 404
PP + P AP P P PP PP PPG P P +AG
Sbjct: 540 SIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAG 594
Score = 70.5 bits (171), Expect = 3e-12
Identities = 52/135 (38%), Positives = 56/135 (41%), Gaps = 31/135 (22%)
Query: 285 GGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPP---PPPSRPSVAVPPPPPNR 341
GGP P PH S P P P+ G P P PPP PPP P + P PP
Sbjct: 385 GGPGGPGGGPH-SFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPP--PPMNQGPHPPGH 441
Query: 342 MYPPPPPALPSSAP-----------SGPPPPPPSVLGVGPVAPPPPP--PPPPPPGP--- 385
PPP S P G PPPP +G+ P PPPP PPPPP GP
Sbjct: 442 HGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPP--MGMMPPPPPPPSGQPPPPPSGPLPP 499
Query: 386 -------PPPPGLPS 393
PPPP PS
Sbjct: 500 WQQQQQQPPPPPPPS 514
Score = 69.3 bits (168), Expect = 8e-12
Identities = 71/223 (31%), Positives = 77/223 (34%), Gaps = 47/223 (21%)
Query: 203 IGTPSNFQHIGHVGWDPNTGFDLNNLDPELKNLFDMCGISEAQLKDRETSKVIYDFIEKT 262
I + FQ G DP + D +D E +L G + TS
Sbjct: 288 IASDCKFQRPG----DPQSAQDKARMDKEYLSLMAELGEAPVPASVGSTS---------- 333
Query: 263 GGVEAVKNELRRQAPP---PPPPSRGGPPPPPPPPHNSGPPPP-PARG-RGAPPPPPSRA 317
G R A P PPPPS PP NSGP P G G P P
Sbjct: 334 GPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGG 393
Query: 318 PTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAP--SGP-------PPPPPSVLGV 368
P + P P P P N PPPP P P GP PPP LG
Sbjct: 394 PHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGS 453
Query: 369 GPVA-------------PPPP----PPPPPPPG--PPPPPGLP 392
PV PPPP PPPPPPP PPPPP P
Sbjct: 454 TPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGP 496
Score = 63.2 bits (152), Expect = 5e-10
Identities = 40/121 (33%), Positives = 46/121 (38%), Gaps = 21/121 (17%)
Query: 262 TGGVEAVKNELRRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAA 321
TG + + + A P P G P P P PP PP PPPPP A
Sbjct: 538 TGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMY 597
Query: 322 PPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPP 381
PPP PPPPP PS+ + V G+ P PP PPPPP
Sbjct: 598 APPP------------------PPPPPMDPSNFVT---MMGMGVAGMPPFGMPPAPPPPP 636
Query: 382 P 382
P
Sbjct: 637 P 637
Score = 48.5 bits (114), Expect = 1e-05
Identities = 41/120 (34%), Positives = 48/120 (40%), Gaps = 7/120 (5%)
Query: 279 PPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPP 338
P P S G P P S P P A PPPP + T + PP S PS + P
Sbjct: 324 PVPASVGSTSGPATTPLASAPRP--AAPANNPPPPSLMSTTQSRPPWMNSGPSES---RP 378
Query: 339 PNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPP-PPPPGPPPPPGLPSDGDH 397
+ M+ P P P P P PS+ G P P PPPP PPP + G H
Sbjct: 379 YHGMHGGGPGG-PGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPH 437
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 95.5 bits (236), Expect = 1e-19
Identities = 62/136 (45%), Positives = 68/136 (50%), Gaps = 25/136 (18%)
Query: 277 PPPPPPSRG---GPPPPPPPPHN-------SGPPPPPARGRGAPP--PPPSRAPTAAPPP 324
P PP PSR PPPPPPP N + PPPPP + P P PS + A PPP
Sbjct: 251 PLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPP 310
Query: 325 PPPSRPSVAVPPPPPNRMYPPPPPALPSS--APSGPPPPPPSVLGVGPVAPPP--PPPPP 380
PPPSRP PP PP+ P LP + S PP PS GP+ PPP PPPP
Sbjct: 311 PPPSRPGP--PPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPP 368
Query: 381 --PPPG-----PPPPP 389
PPG PPPPP
Sbjct: 369 VRDPPGRSGPLPPPPP 384
Score = 90.9 bits (224), Expect = 2e-18
Identities = 66/179 (36%), Positives = 71/179 (39%), Gaps = 63/179 (35%)
Query: 271 ELRRQAPPPPPPSRGGPP---PPPPP---------PHNSGPPPPPARGR----GAPPPP- 313
E +R PPP P G P PPP P PHN G PP P R G PPP
Sbjct: 163 EPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPF 222
Query: 314 ---------------------------------PSRAPTAAPPPPPP---SRPSV---AV 334
PSRA PPPPPP +RPS+ AV
Sbjct: 223 PGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAV 282
Query: 335 PPPPPNRMYPP-PPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGPPPPPGLP 392
PPPPP PP P PS++ PPPPPP P P PPP PP G P LP
Sbjct: 283 PPPPPQNNKPPVPSTPRPSASSQAPPPPPP------PSRPGPPPLPPSSSGNDETPRLP 335
Score = 81.3 bits (199), Expect = 2e-15
Identities = 74/223 (33%), Positives = 88/223 (39%), Gaps = 44/223 (19%)
Query: 276 APPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVP 335
A P PPS G P P P H SGPP P R R PP P + + PPP PS P +
Sbjct: 138 AKPFSPPSGPGRFPVPSPGHRSGPPEPQ-RNRMPPPRPDVGSKPDSIPPPVPSTPR-PIQ 195
Query: 336 PPPPNRMYPPPP--PALPSSAPSGPPPP--PPSVLGVG-----------------PVAPP 374
P NR PP P P PS P+ PP P + LG G P+ P
Sbjct: 196 SSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPT 255
Query: 375 P-------PPPPPPPPGPPP-------PPGLPSDGDHQVPTTAGNKAALLDQIREGAQLK 420
P PPPPPPP G P PP P + VP+T +A
Sbjct: 256 PSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTP-RPSASSQAPPPPPPPS 314
Query: 421 KVEQNSRPVSCSGRDALLDQIRQGIQLKSVADGQESTPPTPAP 463
+ P S SG D ++ + L S STPP P+P
Sbjct: 315 RPGPPPLPPSSSGNDETPRLPQRNLSLSS------STPPLPSP 351
Score = 78.6 bits (192), Expect = 1e-14
Identities = 55/163 (33%), Positives = 62/163 (38%), Gaps = 63/163 (38%)
Query: 277 PPPPPPSRGGPPPPPP-----------PPHN----SGPPPPPARGRGAPPPPPSRAPTAA 321
PPPPPPSR GPPP PP P N S PP P+ GR P PPP P+
Sbjct: 308 PPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPP---PSER 364
Query: 322 PPPP---PPSRPSVAVPPPPPNRM--------------------------YPPPPPALPS 352
PPPP PP R PPPP +R PP PP PS
Sbjct: 365 PPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPS 424
Query: 353 SAPSGPPPPPPSVLG----------------VGPVAPPPPPPP 379
+ PPPP S+ P++ PPP P
Sbjct: 425 AGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEP 467
Score = 57.4 bits (137), Expect = 3e-08
Identities = 40/102 (39%), Positives = 41/102 (40%), Gaps = 13/102 (12%)
Query: 297 SGPP--PPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSA 354
S PP PP R A P P P P P P R PP P R PPP S
Sbjct: 124 SRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSG----PPEPQRNRMPPPRPDVGSK 179
Query: 355 PSGPPPPPPSVLGVGPVAP-----PPPP--PPPPPPGPPPPP 389
P PPP PS +P PP P P P PGP PPP
Sbjct: 180 PDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPP 221
Score = 39.7 bits (91), Expect = 0.006
Identities = 21/53 (39%), Positives = 25/53 (47%), Gaps = 3/53 (5%)
Query: 378 PPPPPPGPPPPPGLPSDGDHQV---PTTAGNKAALLDQIREGAQLKKVEQNSR 427
P PPPP PPPPP + T + ALL I +G +LKK N R
Sbjct: 2 PVPPPPAPPPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDR 54
Score = 32.0 bits (71), Expect = 1.4
Identities = 25/100 (25%), Positives = 36/100 (36%), Gaps = 5/100 (5%)
Query: 264 GVEAVKNELRRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPP 323
GV++ ++ R PP P + PPPPP +G P SR
Sbjct: 406 GVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEW-----ESRFYFHPIS 460
Query: 324 PPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPP 363
PP P V P+++ + + G PP PP
Sbjct: 461 DLPPPEPYVQTTKSYPSKLARNESRSGSNRRERGAPPLPP 500
Score = 31.2 bits (69), Expect = 2.3
Identities = 26/88 (29%), Positives = 28/88 (31%), Gaps = 35/88 (39%)
Query: 277 PPPPP--PSRGGPPPPPPP-----------------------PHNSGPPPPP-------- 303
PP PP PS G PPPPPP P + PPP P
Sbjct: 416 PPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSY 475
Query: 304 --ARGRGAPPPPPSRAPTAAPPPPPPSR 329
R +R APP PP R
Sbjct: 476 PSKLARNESRSGSNRRERGAPPLPPIPR 503
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 95.5 bits (236), Expect = 1e-19
Identities = 62/136 (45%), Positives = 68/136 (50%), Gaps = 25/136 (18%)
Query: 277 PPPPPPSRG---GPPPPPPPPHN-------SGPPPPPARGRGAPP--PPPSRAPTAAPPP 324
P PP PSR PPPPPPP N + PPPPP + P P PS + A PPP
Sbjct: 251 PLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPP 310
Query: 325 PPPSRPSVAVPPPPPNRMYPPPPPALPSS--APSGPPPPPPSVLGVGPVAPPP--PPPPP 380
PPPSRP PP PP+ P LP + S PP PS GP+ PPP PPPP
Sbjct: 311 PPPSRPGP--PPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPP 368
Query: 381 --PPPG-----PPPPP 389
PPG PPPPP
Sbjct: 369 VRDPPGRSGPLPPPPP 384
Score = 90.9 bits (224), Expect = 2e-18
Identities = 66/179 (36%), Positives = 71/179 (39%), Gaps = 63/179 (35%)
Query: 271 ELRRQAPPPPPPSRGGPP---PPPPP---------PHNSGPPPPPARGR----GAPPPP- 313
E +R PPP P G P PPP P PHN G PP P R G PPP
Sbjct: 163 EPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPF 222
Query: 314 ---------------------------------PSRAPTAAPPPPPP---SRPSV---AV 334
PSRA PPPPPP +RPS+ AV
Sbjct: 223 PGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAV 282
Query: 335 PPPPPNRMYPP-PPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGPPPPPGLP 392
PPPPP PP P PS++ PPPPPP P P PPP PP G P LP
Sbjct: 283 PPPPPQNNKPPVPSTPRPSASSQAPPPPPP------PSRPGPPPLPPSSSGNDETPRLP 335
Score = 81.3 bits (199), Expect = 2e-15
Identities = 74/223 (33%), Positives = 88/223 (39%), Gaps = 44/223 (19%)
Query: 276 APPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVP 335
A P PPS G P P P H SGPP P R R PP P + + PPP PS P +
Sbjct: 138 AKPFSPPSGPGRFPVPSPGHRSGPPEPQ-RNRMPPPRPDVGSKPDSIPPPVPSTPR-PIQ 195
Query: 336 PPPPNRMYPPPP--PALPSSAPSGPPPP--PPSVLGVG-----------------PVAPP 374
P NR PP P P PS P+ PP P + LG G P+ P
Sbjct: 196 SSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPT 255
Query: 375 P-------PPPPPPPPGPPP-------PPGLPSDGDHQVPTTAGNKAALLDQIREGAQLK 420
P PPPPPPP G P PP P + VP+T +A
Sbjct: 256 PSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTP-RPSASSQAPPPPPPPS 314
Query: 421 KVEQNSRPVSCSGRDALLDQIRQGIQLKSVADGQESTPPTPAP 463
+ P S SG D ++ + L S STPP P+P
Sbjct: 315 RPGPPPLPPSSSGNDETPRLPQRNLSLSS------STPPLPSP 351
Score = 78.6 bits (192), Expect = 1e-14
Identities = 55/163 (33%), Positives = 62/163 (38%), Gaps = 63/163 (38%)
Query: 277 PPPPPPSRGGPPPPPP-----------PPHN----SGPPPPPARGRGAPPPPPSRAPTAA 321
PPPPPPSR GPPP PP P N S PP P+ GR P PPP P+
Sbjct: 308 PPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPP---PSER 364
Query: 322 PPPP---PPSRPSVAVPPPPPNRM--------------------------YPPPPPALPS 352
PPPP PP R PPPP +R PP PP PS
Sbjct: 365 PPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPS 424
Query: 353 SAPSGPPPPPPSVLG----------------VGPVAPPPPPPP 379
+ PPPP S+ P++ PPP P
Sbjct: 425 AGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEP 467
Score = 57.4 bits (137), Expect = 3e-08
Identities = 40/102 (39%), Positives = 41/102 (40%), Gaps = 13/102 (12%)
Query: 297 SGPP--PPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSA 354
S PP PP R A P P P P P P R PP P R PPP S
Sbjct: 124 SRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSG----PPEPQRNRMPPPRPDVGSK 179
Query: 355 PSGPPPPPPSVLGVGPVAP-----PPPP--PPPPPPGPPPPP 389
P PPP PS +P PP P P P PGP PPP
Sbjct: 180 PDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPP 221
Score = 39.7 bits (91), Expect = 0.006
Identities = 21/53 (39%), Positives = 25/53 (47%), Gaps = 3/53 (5%)
Query: 378 PPPPPPGPPPPPGLPSDGDHQV---PTTAGNKAALLDQIREGAQLKKVEQNSR 427
P PPPP PPPPP + T + ALL I +G +LKK N R
Sbjct: 2 PVPPPPAPPPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDR 54
Score = 32.0 bits (71), Expect = 1.4
Identities = 25/100 (25%), Positives = 36/100 (36%), Gaps = 5/100 (5%)
Query: 264 GVEAVKNELRRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPP 323
GV++ ++ R PP P + PPPPP +G P SR
Sbjct: 406 GVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEW-----ESRFYFHPIS 460
Query: 324 PPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPP 363
PP P V P+++ + + G PP PP
Sbjct: 461 DLPPPEPYVQTTKSYPSKLARNESRSGSNRRERGAPPLPP 500
Score = 31.2 bits (69), Expect = 2.3
Identities = 26/88 (29%), Positives = 28/88 (31%), Gaps = 35/88 (39%)
Query: 277 PPPPP--PSRGGPPPPPPP-----------------------PHNSGPPPPP-------- 303
PP PP PS G PPPPPP P + PPP P
Sbjct: 416 PPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSY 475
Query: 304 --ARGRGAPPPPPSRAPTAAPPPPPPSR 329
R +R APP PP R
Sbjct: 476 PSKLARNESRSGSNRRERGAPPLPPIPR 503
>gi|56118221 amyloid beta (A4) precursor protein-binding, family B,
member 1 interacting protein [Homo sapiens]
Length = 666
Score = 94.7 bits (234), Expect = 2e-19
Identities = 53/131 (40%), Positives = 60/131 (45%), Gaps = 20/131 (15%)
Query: 267 AVKNELRRQAPPPPPPSRGGPPPPPPPPHNS---GPPPPPAR-----GRGAPPPPPSRAP 318
A+ N P P + PPPPP +S G P P + G G P PP P
Sbjct: 496 ALGNHHDPAVPRAPHAPKSSLPPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPDDFLP 555
Query: 319 TAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPP 378
PPPPPP +PPPPP+ M PPP PPPPPS G+ PPPPP
Sbjct: 556 ---PPPPPPPLDDPELPPPPPDFMEPPPDFV---------PPPPPSYAGIAGSELPPPPP 603
Query: 379 PPPPPGPPPPP 389
PPP P P P P
Sbjct: 604 PPPAPAPAPVP 614
Score = 71.2 bits (173), Expect = 2e-12
Identities = 50/128 (39%), Positives = 55/128 (42%), Gaps = 29/128 (22%)
Query: 263 GGVEAVKNELRRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAP 322
GG+ A ++ PPPPP P PPPPP PPP PPPPPS A A
Sbjct: 544 GGLPAPPDDFLPPPPPPPP--LDDPELPPPPPDFMEPPPD-----FVPPPPPSYAGIAGS 596
Query: 323 PPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPP 382
PPP PPPPP P P +P SA PPP+ VA PP PP
Sbjct: 597 ELPPP-------PPPPP----APAPAPVPDSA-----RPPPA------VAKRPPVPPKRQ 634
Query: 383 PGPPPPPG 390
P P G
Sbjct: 635 ENPGHPGG 642
Score = 42.4 bits (98), Expect = 0.001
Identities = 28/78 (35%), Positives = 30/78 (38%), Gaps = 25/78 (32%)
Query: 337 PPPNRMYPPPPPALPSSAPSGPPPPPP------------------SVLGVGPVAPP---- 374
P + P P P + S PPPPP G G APP
Sbjct: 495 PALGNHHDPAVPRAPHAPKSSLPPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPDDFL 554
Query: 375 PPPPPPPP---PGPPPPP 389
PPPPPPPP P PPPP
Sbjct: 555 PPPPPPPPLDDPELPPPP 572
Score = 32.0 bits (71), Expect = 1.4
Identities = 19/60 (31%), Positives = 29/60 (48%), Gaps = 5/60 (8%)
Query: 367 GVGPVAPPPPPPPPPP----PGPPPPPGLPSDGDHQVPTTAGNKAALLDQIREGAQLKKV 422
G+ PPPP P P PPPPP S + + A L++++E A++KK+
Sbjct: 120 GISQYEDDLPPPPADPVLDLPLPPPPPEPLSQEEEEAQAKADKIKLALEKLKE-AKVKKL 178
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.135 0.421
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,089,118
Number of Sequences: 37866
Number of extensions: 3551799
Number of successful extensions: 203130
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 2512
Number of HSP's successfully gapped in prelim test: 1619
Number of HSP's that attempted gapping in prelim test: 26772
Number of HSP's gapped (non-prelim): 52938
length of query: 505
length of database: 18,247,518
effective HSP length: 107
effective length of query: 398
effective length of database: 14,195,856
effective search space: 5649950688
effective search space used: 5649950688
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.