BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|50658077 phosphodiesterase 4D interacting protein isoform 4 [Homo sapiens] (173 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|50658069 phosphodiesterase 4D interacting protein isoform 2 [... 343 6e-95 gi|157311604 phosphodiesterase 4D interacting protein isoform 1 ... 343 6e-95 gi|50658077 phosphodiesterase 4D interacting protein isoform 4 [... 343 6e-95 gi|50658075 phosphodiesterase 4D interacting protein isoform 3 [... 325 1e-89 gi|88943074 PREDICTED: similar to Phosphodiesterase 4D interacti... 248 1e-66 gi|58535453 CDK5 regulatory subunit associated protein 2 isoform... 120 8e-28 gi|58535451 CDK5 regulatory subunit associated protein 2 isoform... 120 8e-28 gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 50 1e-06 gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens] 47 6e-06 gi|55770834 centromere protein F [Homo sapiens] 47 8e-06 gi|148746195 trichohyalin [Homo sapiens] 46 1e-05 gi|190341068 forkhead-associated (FHA) phosphopeptide binding do... 45 4e-05 gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 44 5e-05 gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 44 5e-05 gi|4885583 Rho-associated, coiled-coil containing protein kinase... 44 7e-05 gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 44 7e-05 gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens] 44 9e-05 gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 44 9e-05 gi|156104908 myosin heavy chain 6 [Homo sapiens] 44 9e-05 gi|119120861 formin-like 3 isoform 2 [Homo sapiens] 43 1e-04 gi|119120874 formin-like 3 isoform 1 [Homo sapiens] 43 1e-04 gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo ... 43 1e-04 gi|50658071 phosphodiesterase 4D interacting protein isoform 5 [... 43 2e-04 gi|16262452 cingulin [Homo sapiens] 43 2e-04 gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens] 43 2e-04 gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 42 2e-04 gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 42 2e-04 gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo sapi... 42 2e-04 gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 42 2e-04 gi|29171755 PTPRF interacting protein alpha 2 [Homo sapiens] 42 2e-04 >gi|50658069 phosphodiesterase 4D interacting protein isoform 2 [Homo sapiens] Length = 969 Score = 343 bits (879), Expect = 6e-95 Identities = 173/173 (100%), Positives = 173/173 (100%) Query: 1 MSNGYRTLSQHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKR 60 MSNGYRTLSQHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKR Sbjct: 1 MSNGYRTLSQHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKR 60 Query: 61 ELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAK 120 ELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAK Sbjct: 61 ELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAK 120 Query: 121 NEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTEALAQRDK 173 NEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTEALAQRDK Sbjct: 121 NEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTEALAQRDK 173 Score = 42.7 bits (99), Expect = 2e-04 Identities = 35/115 (30%), Positives = 52/115 (45%), Gaps = 16/115 (13%) Query: 31 ERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQ 90 E + E +E +K N EL+ ++ L+ ELQ+K Q L + W EAE + Sbjct: 380 EAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQL-RAW----------EAEKYNE 428 Query: 91 FEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLK 145 ++Q +H+ L +K QLLQE L + L E N L EKL+ Sbjct: 429 IRTQEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTL-----EANEMLLEKLR 478 >gi|157311604 phosphodiesterase 4D interacting protein isoform 1 [Homo sapiens] Length = 2346 Score = 343 bits (879), Expect = 6e-95 Identities = 173/173 (100%), Positives = 173/173 (100%) Query: 1 MSNGYRTLSQHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKR 60 MSNGYRTLSQHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKR Sbjct: 1 MSNGYRTLSQHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKR 60 Query: 61 ELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAK 120 ELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAK Sbjct: 61 ELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAK 120 Query: 121 NEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTEALAQRDK 173 NEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTEALAQRDK Sbjct: 121 NEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTEALAQRDK 173 Score = 42.7 bits (99), Expect = 2e-04 Identities = 35/115 (30%), Positives = 52/115 (45%), Gaps = 16/115 (13%) Query: 31 ERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQ 90 E + E +E +K N EL+ ++ L+ ELQ+K Q L + W EAE + Sbjct: 380 EAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQL-RAW----------EAEKYNE 428 Query: 91 FEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLK 145 ++Q +H+ L +K QLLQE L + L E N L EKL+ Sbjct: 429 IRTQEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTL-----EANEMLLEKLR 478 Score = 36.2 bits (82), Expect = 0.015 Identities = 29/109 (26%), Positives = 48/109 (44%), Gaps = 13/109 (11%) Query: 54 EVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQ 113 E ESL+ L + HL + E EL Q ERQQ E + E + + + Sbjct: 1928 ETESLREALLSSRSHLQEL-----------EKELEHQKVERQQLLEDLREKQQEVLHFRE 1976 Query: 114 EESRLAKNEAARMAALVEAEKEC--NLELSEKLKGVTKNWEDVPGDQVK 160 E L +N++ LV +++C +L E L+ + +E + G+ K Sbjct: 1977 ERLSLQENDSRLQHKLVLLQQQCEEKQQLFESLQSELQIYEALYGNSKK 2025 >gi|50658077 phosphodiesterase 4D interacting protein isoform 4 [Homo sapiens] Length = 173 Score = 343 bits (879), Expect = 6e-95 Identities = 173/173 (100%), Positives = 173/173 (100%) Query: 1 MSNGYRTLSQHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKR 60 MSNGYRTLSQHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKR Sbjct: 1 MSNGYRTLSQHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKR 60 Query: 61 ELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAK 120 ELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAK Sbjct: 61 ELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAK 120 Query: 121 NEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTEALAQRDK 173 NEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTEALAQRDK Sbjct: 121 NEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTEALAQRDK 173 >gi|50658075 phosphodiesterase 4D interacting protein isoform 3 [Homo sapiens] Length = 310 Score = 325 bits (833), Expect = 1e-89 Identities = 164/168 (97%), Positives = 165/168 (98%) Query: 6 RTLSQHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDK 65 R +HLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDK Sbjct: 143 RDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDK 202 Query: 66 KQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAAR 125 KQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAAR Sbjct: 203 KQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAAR 262 Query: 126 MAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTEALAQRDK 173 MAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTEALAQRDK Sbjct: 263 MAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTEALAQRDK 310 >gi|88943074 PREDICTED: similar to Phosphodiesterase 4D interacting protein [Homo sapiens] Length = 134 Score = 248 bits (634), Expect = 1e-66 Identities = 125/127 (98%), Positives = 126/127 (99%) Query: 47 RNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLE 106 +N ELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLE Sbjct: 8 QNTELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLE 67 Query: 107 NKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTE 166 NKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTE Sbjct: 68 NKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTE 127 Query: 167 ALAQRDK 173 ALAQRDK Sbjct: 128 ALAQRDK 134 >gi|58535453 CDK5 regulatory subunit associated protein 2 isoform b [Homo sapiens] Length = 1814 Score = 120 bits (300), Expect = 8e-28 Identities = 67/147 (45%), Positives = 93/147 (63%) Query: 6 RTLSQHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDK 65 + + +LKKENF+LKLRIYFLEERMQQ++ E IYK NIELKVEVESLKRELQ++ Sbjct: 61 KDFENQITELKKENFNLKLRIYFLEERMQQEFHGPTEHIYKTNIELKVEVESLKRELQER 120 Query: 66 KQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAAR 125 +Q L K VE+L +E++R E+ +++ + V +LL +I LL+++ A+ E + Sbjct: 121 EQLLIKASKAVESLAEAGGSEIQRVKEDARKKVQQVEDLLTKRILLLEKDVTAAQAELEK 180 Query: 126 MAALVEAEKECNLELSEKLKGVTKNWE 152 A E EK L L KL + K E Sbjct: 181 AFAGTETEKALRLRLESKLSEMKKMHE 207 Score = 32.7 bits (73), Expect = 0.16 Identities = 30/109 (27%), Positives = 60/109 (55%), Gaps = 15/109 (13%) Query: 6 RTLSQHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDK 65 + ++Q L+DL++E L+ LEE ++K S+ D R +L+ EVE L+ E+ ++ Sbjct: 402 KKITQELSDLQQERERLEKD---LEEAHREK---SKGDCTIR--DLRNEVEKLRNEVNER 453 Query: 66 KQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQE 114 ++ ++ + ++L S++ +L Q +Q +H+ E K LLQ+ Sbjct: 454 EKAMENRY---KSLLSESNKKLHNQ----EQVIKHLTESTNQKDVLLQK 495 Score = 31.6 bits (70), Expect = 0.36 Identities = 27/107 (25%), Positives = 49/107 (45%), Gaps = 15/107 (14%) Query: 50 ELKVEVESLKRELQDKKQHLDKTWADVENLNSQN--------EAELRRQFEERQQETEHV 101 ELK+ ++S + +Q K+ + EN++S E R+ E Q E + Sbjct: 225 ELKLSLKSKEALIQCLKEEKSQMACPDENVSSGELRGLCAAPREEKERETEAAQMEHQKE 284 Query: 102 YELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVT 148 E +IQ L+E+ R + E A EK+ +L+ + ++G+T Sbjct: 285 RNSFEERIQALEEDLREKEREIA-------TEKKNSLKRDKAIQGLT 324 >gi|58535451 CDK5 regulatory subunit associated protein 2 isoform a [Homo sapiens] Length = 1893 Score = 120 bits (300), Expect = 8e-28 Identities = 67/147 (45%), Positives = 93/147 (63%) Query: 6 RTLSQHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDK 65 + + +LKKENF+LKLRIYFLEERMQQ++ E IYK NIELKVEVESLKRELQ++ Sbjct: 61 KDFENQITELKKENFNLKLRIYFLEERMQQEFHGPTEHIYKTNIELKVEVESLKRELQER 120 Query: 66 KQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAAR 125 +Q L K VE+L +E++R E+ +++ + V +LL +I LL+++ A+ E + Sbjct: 121 EQLLIKASKAVESLAEAGGSEIQRVKEDARKKVQQVEDLLTKRILLLEKDVTAAQAELEK 180 Query: 126 MAALVEAEKECNLELSEKLKGVTKNWE 152 A E EK L L KL + K E Sbjct: 181 AFAGTETEKALRLRLESKLSEMKKMHE 207 Score = 32.7 bits (73), Expect = 0.16 Identities = 30/109 (27%), Positives = 60/109 (55%), Gaps = 15/109 (13%) Query: 6 RTLSQHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDK 65 + ++Q L+DL++E L+ LEE ++K S+ D R +L+ EVE L+ E+ ++ Sbjct: 402 KKITQELSDLQQERERLEKD---LEEAHREK---SKGDCTIR--DLRNEVEKLRNEVNER 453 Query: 66 KQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQE 114 ++ ++ + ++L S++ +L Q +Q +H+ E K LLQ+ Sbjct: 454 EKAMENRY---KSLLSESNKKLHNQ----EQVIKHLTESTNQKDVLLQK 495 Score = 31.6 bits (70), Expect = 0.36 Identities = 27/107 (25%), Positives = 49/107 (45%), Gaps = 15/107 (14%) Query: 50 ELKVEVESLKRELQDKKQHLDKTWADVENLNSQN--------EAELRRQFEERQQETEHV 101 ELK+ ++S + +Q K+ + EN++S E R+ E Q E + Sbjct: 225 ELKLSLKSKEALIQCLKEEKSQMACPDENVSSGELRGLCAAPREEKERETEAAQMEHQKE 284 Query: 102 YELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVT 148 E +IQ L+E+ R + E A EK+ +L+ + ++G+T Sbjct: 285 RNSFEERIQALEEDLREKEREIA-------TEKKNSLKRDKAIQGLT 324 >gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo sapiens] Length = 1870 Score = 49.7 bits (117), Expect = 1e-06 Identities = 38/147 (25%), Positives = 79/147 (53%), Gaps = 7/147 (4%) Query: 12 LNDLKKENFSLKLRIYFLEE---RMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQH 68 + +L+KEN +L I +E R+++ + ++E + + I++K V +L+ +L +K Sbjct: 859 IGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLV-TLREDLVSEKLK 917 Query: 69 LDKTWADVENLNSQNE--AELRRQFEERQQETEHVYELLENKIQ-LLQEESRLAKNEAAR 125 + D+E L + E + + +Q T+ Y+LLE+K++ L++ + + + A Sbjct: 918 TQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAA 977 Query: 126 MAALVEAEKECNLELSEKLKGVTKNWE 152 + A +E N +L ++LK V KN+E Sbjct: 978 LEARLEESTNYNQQLRQELKTVKKNYE 1004 Score = 39.3 bits (90), Expect = 0.002 Identities = 39/140 (27%), Positives = 66/140 (47%), Gaps = 10/140 (7%) Query: 15 LKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWA 74 L++EN L + L +R Q EA +DI K N K+ ES+K + L K Sbjct: 556 LEQENEHLNQTVSSLRQRSQISAEARVKDIEKEN---KILHESIK----ETSSKLSK--I 606 Query: 75 DVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEK 134 + E + E E ++ ER +E E+ LE + +LLQ++ K ++ AL + Sbjct: 607 EFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENS 666 Query: 135 ECNLELSEKLKGVTKNWEDV 154 E E + KLK +++++ Sbjct: 667 ELERE-NRKLKKTLDSFKNL 685 Score = 35.4 bits (80), Expect = 0.025 Identities = 36/142 (25%), Positives = 66/142 (46%), Gaps = 21/142 (14%) Query: 13 NDLKKENFSL------KLRIYFLEERMQQKY---EASREDIYKRNIELKVE-VESLKREL 62 NDL+K L K R+ E+ +Y E+ E K+++E+K E + +L+ L Sbjct: 923 NDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARL 982 Query: 63 QDKKQHLDKTWADVENLNSQNEAELRRQFEERQ---------QETEHVYELLENKIQLLQ 113 ++ + + +++ + EA +RQ EER ++ + E E +LL+ Sbjct: 983 EESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLK 1042 Query: 114 EESRLAKNEAARMAALVEAEKE 135 + RL E R A ++AEK+ Sbjct: 1043 VKDRLI--EVERNNATLQAEKQ 1062 Score = 34.7 bits (78), Expect = 0.042 Identities = 43/182 (23%), Positives = 81/182 (44%), Gaps = 27/182 (14%) Query: 8 LSQHLNDLKKENFSLKLRIYFLEERMQQKYEASRED--IYKRNIELKVEVESLK------ 59 L Q ++L++EN LK + + Q +E+ + + N+EL+ VESLK Sbjct: 661 LEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKM 720 Query: 60 -------RELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLL 112 +EL+ +K+ L K ++ + + L ++ E + + + LEN + + Sbjct: 721 AQLQLENKELESEKEQL-KKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKI 779 Query: 113 QE-ESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTEALAQR 171 Q+ ES L +E E + + E+LK +K E + + +Q T L ++ Sbjct: 780 QQLESELQD---------LEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQL-EK 829 Query: 172 DK 173 DK Sbjct: 830 DK 831 Score = 32.7 bits (73), Expect = 0.16 Identities = 38/145 (26%), Positives = 68/145 (46%), Gaps = 14/145 (9%) Query: 9 SQHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYK---RNIELKVEVESLKRELQDK 65 S L L+ EN SL + L + E + I K N L +VE L+ E+ + Sbjct: 459 SSRLLKLEMENQSLTKTVEELRTTVDS-VEGNASKILKMEKENQRLSKKVEILENEIVQE 517 Query: 66 KQHLDKTWADVENLNS---QNEAELRRQFEERQQETEHVYELLENKIQLLQE--ESRLAK 120 KQ L + +NL+ + +A+L + E ++ +E ++LE + + L + S + Sbjct: 518 KQSLQ----NCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQR 573 Query: 121 NEAARMAALVEAEKECNLELSEKLK 145 ++ + A + + EKE N L E +K Sbjct: 574 SQISAEARVKDIEKE-NKILHESIK 597 Score = 32.7 bits (73), Expect = 0.16 Identities = 44/168 (26%), Positives = 75/168 (44%), Gaps = 24/168 (14%) Query: 2 SNGYRTLSQHLNDLKKENFSLKLRIYFLEERMQQ----------KYEASREDIYKRNIEL 51 +N + L Q L +KK +LK R EERM Q K+E ++ + +++ Sbjct: 986 TNYNQQLRQELKTVKKNYEALKQRQD--EERMVQSSPPISGEDNKWERESQETTRELLKV 1043 Query: 52 K---VEVESLKRELQDKKQHLDKTWADVENLNSQNEAE---LRRQFEERQQ-----ETEH 100 K +EVE LQ +KQ L +E N+ +A+ L+RQ Q+ +T++ Sbjct: 1044 KDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQN 1103 Query: 101 VYELLENKIQLLQEESRLAKN-EAARMAALVEAEKECNLELSEKLKGV 147 +EN Q S + +N + + +E E E ++ E LK + Sbjct: 1104 AKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSL 1151 Score = 28.9 bits (63), Expect = 2.3 Identities = 34/152 (22%), Positives = 64/152 (42%), Gaps = 44/152 (28%) Query: 36 KYEASREDIYKRNIELKVEVESLKRELQDK-------KQHLDKTWADV-----ENLNSQN 83 K SR+ + + K ++ L++EL++K KQ L++ ++ EN+N + Sbjct: 241 KRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLS 300 Query: 84 EAELRRQFEE--------------------RQQETEHVYELLENKIQLLQEESRL----- 118 +A R + + R +E H E + +++ L+E++++ Sbjct: 301 DARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETK 360 Query: 119 ------AKNEAARMAALVEAEKECNLELSEKL 144 + AR L E EKE NL+L KL Sbjct: 361 TMLEDQLEGTRARSDKLHELEKE-NLQLKAKL 391 Score = 26.9 bits (58), Expect = 8.8 Identities = 20/83 (24%), Positives = 37/83 (44%), Gaps = 9/83 (10%) Query: 35 QKYEASREDIYKRNIELKVEVESLKRELQDKKQHL---------DKTWADVENLNSQNEA 85 QK E E I + + K V + +E+ ++++ D + D+E L Sbjct: 136 QKKEEFIERIQGLDFDTKAAVAAHIQEVTHNQENVFDLQWMEVTDMSQEDIEPLLKNMAL 195 Query: 86 ELRRQFEERQQETEHVYELLENK 108 L+R +ER + +E + EL E + Sbjct: 196 HLKRLIDERDEHSETIIELSEER 218 >gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens] Length = 1317 Score = 47.4 bits (111), Expect = 6e-06 Identities = 42/128 (32%), Positives = 68/128 (53%), Gaps = 17/128 (13%) Query: 31 ERMQQKYEASREDIYKRNIELKVEVESLKR---ELQDKKQHL--DKTWADVENLNSQNEA 85 ERMQQ+ E R++ ++++ + ESLKR +++K + L +K + E L Q E Sbjct: 631 ERMQQEVETQRKETEIVQLQIRKQEESLKRRSFHIENKLKDLLAEKEKFEEERLREQQEI 690 Query: 86 ELRRQFEER------QQETEHVYELLEN----KIQLLQEESRLAKNEAARMAALVEAEKE 135 EL+++ +E Q+E + + EL N K Q+ QE +L K + + A L E EK+ Sbjct: 691 ELQKKRQEEETFLRVQEELQRLKELNNNEKAEKFQIFQELDQLQKEKDEQYAKL-ELEKK 749 Query: 136 CNLELSEK 143 LE EK Sbjct: 750 -RLEEQEK 756 Score = 29.3 bits (64), Expect = 1.8 Identities = 25/104 (24%), Positives = 50/104 (48%), Gaps = 3/104 (2%) Query: 53 VEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRR---QFEERQQETEHVYELLENKI 109 +E E +RE +K + K ++E ++AEL R + E +++ETE V + + Sbjct: 596 LEFERQQREELEKLESKRKLIEEMEEKQKSDKAELERMQQEVETQRKETEIVQLQIRKQE 655 Query: 110 QLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWED 153 + L+ S +N+ + A E +E L ++++ K E+ Sbjct: 656 ESLKRRSFHIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEE 699 >gi|55770834 centromere protein F [Homo sapiens] Length = 3114 Score = 47.0 bits (110), Expect = 8e-06 Identities = 37/145 (25%), Positives = 72/145 (49%), Gaps = 2/145 (1%) Query: 8 LSQHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQ 67 +++ L + ++EN SLK ++ LE +Q E ++E + K EVE+LK ++++ + Sbjct: 2138 IAEKLKERERENDSLKDKVENLERELQMS-EENQELVILDAENSKAEVETLKTQIEEMAR 2196 Query: 68 HLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMA 127 L D+ L S+ E L +Q +E+Q + + +LL + LL+E+ + Sbjct: 2197 SLKVFELDLVTLRSEKE-NLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESK 2255 Query: 128 ALVEAEKECNLELSEKLKGVTKNWE 152 VE + EL+E + + + E Sbjct: 2256 TAVEMLQNQLKELNEAVAALCGDQE 2280 Score = 40.8 bits (94), Expect = 6e-04 Identities = 34/125 (27%), Positives = 64/125 (51%), Gaps = 5/125 (4%) Query: 10 QHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHL 69 + ++ L++ L++RI +E+ Q ++ + N LK +VE+L+RELQ +++ Sbjct: 2112 EEVHQLRRGIEKLRVRIE-ADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQ 2170 Query: 70 DKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAAL 129 + D EN ++ E L+ Q EE + + V+EL + + L E+ L K + L Sbjct: 2171 ELVILDAENSKAEVET-LKTQIEEMARSLK-VFEL--DLVTLRSEKENLTKQIQEKQGQL 2226 Query: 130 VEAEK 134 E +K Sbjct: 2227 SELDK 2231 Score = 37.0 bits (84), Expect = 0.009 Identities = 40/142 (28%), Positives = 69/142 (48%), Gaps = 25/142 (17%) Query: 16 KKENFSLKLRIYFLEERMQ--QKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDK-T 72 K++N L+ LE+++Q Q AS +D + L+ ++L+ EL+ K +DK + Sbjct: 2552 KEQNLELRNLTVELEQKIQVLQSKNASLQDTLE---VLQSSYKNLENELELTK--MDKMS 2606 Query: 73 WADVENLNSQNEAELRRQFEERQQETEHVYELLENK-------IQLLQEESRLAKNEAAR 125 + + N + E EL+R+ E Q+T + E L + +QLL EE + +K++ Sbjct: 2607 FVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQL-- 2664 Query: 126 MAALVEAEKECNLELSEKLKGV 147 KE LE SE K + Sbjct: 2665 --------KELTLENSELKKSL 2678 Score = 35.0 bits (79), Expect = 0.032 Identities = 36/146 (24%), Positives = 70/146 (47%), Gaps = 19/146 (13%) Query: 15 LKKENFSLKLRIYFLEERM------QQKYEASREDIYKRNIELKVEVESLKRELQDKKQH 68 L+K+N + + I LEE + + + + + K+ L + L ++++K Q Sbjct: 1935 LEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTAL----DQLSEKMKEKTQE 1990 Query: 69 LDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLEN------KIQLLQEESR---LA 119 L+ ++ + EAE++ + E Q + V ELL++ K+Q L+++S+ L Sbjct: 1991 LESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLT 2050 Query: 120 KNEAARMAALVEAEKECNLELSEKLK 145 K E A + EKE ++ SE L+ Sbjct: 2051 KCELENQIAQLNKEKELLVKESESLQ 2076 Score = 33.9 bits (76), Expect = 0.072 Identities = 31/120 (25%), Positives = 62/120 (51%), Gaps = 13/120 (10%) Query: 32 RMQQKYEAS--REDIYKRNIE-LKVEVESLKRELQDKKQHLDKTWADVENLN-----SQN 83 R +Q ++AS +E+ +R++E +K E LK + K + + A+++N+ SQN Sbjct: 462 RAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQN 521 Query: 84 EAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEK 143 AE + + + E + L+ KI Q+E+ L + A +E +++C+ +L +K Sbjct: 522 FAE---EMKAKNTSQETMLRDLQEKIN--QQENSLTLEKLKLAVADLEKQRDCSQDLLKK 576 Score = 33.1 bits (74), Expect = 0.12 Identities = 30/140 (21%), Positives = 65/140 (46%), Gaps = 13/140 (9%) Query: 6 RTLSQHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDK 65 +TLS +++L K+ L+ ++ LE+ Q ++ ++ + +L E E L +E + Sbjct: 2017 QTLSSDVSELLKDKTHLQEKLQSLEKD-SQALSLTKCELENQIAQLNKEKELLVKESESL 2075 Query: 66 KQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAAR 125 + L ++ + N++ EA L + E ++ QEE + + Sbjct: 2076 QARLSESDYEKLNVSKALEAALVEKGE------------FALRLSSTQEEVHQLRRGIEK 2123 Query: 126 MAALVEAEKECNLELSEKLK 145 + +EA+++ L ++EKLK Sbjct: 2124 LRVRIEADEKKQLHIAEKLK 2143 Score = 33.1 bits (74), Expect = 0.12 Identities = 36/148 (24%), Positives = 69/148 (46%), Gaps = 18/148 (12%) Query: 16 KKENFSLKLRIYFLEE-RMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWA 74 K++N S ++ LE+ ++ Q + ++ + I L+ V L +E++D KQ L+K Sbjct: 2467 KEQNLSSQVECLELEKAQLLQGLDEAKNNY----IVLQSSVNGLIQEVEDGKQKLEKKDE 2522 Query: 75 DVENLNSQ-----------NEAELRRQ-FEERQQETEHVYELLENKIQLLQ-EESRLAKN 121 ++ L +Q ++ E Q ++E+ E ++ LE KIQ+LQ + + L Sbjct: 2523 EISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDT 2582 Query: 122 EAARMAALVEAEKECNLELSEKLKGVTK 149 ++ E E L +K+ V K Sbjct: 2583 LEVLQSSYKNLENELELTKMDKMSFVEK 2610 Score = 32.3 bits (72), Expect = 0.21 Identities = 43/195 (22%), Positives = 69/195 (35%), Gaps = 40/195 (20%) Query: 3 NGYRTLSQHLNDLKKENFSLKLRIYFLEERMQQKY-------EASREDIYKRNIELKVEV 55 N L Q KE+ ++ F EER Q +A R ++ K E Sbjct: 1066 NRKNELEQLKEAFAKEHQEFLTKLAFAEERNQNLMLELETVQQALRSEMTDNQNNSKSEA 1125 Query: 56 ESLKRELQDKKQHLDKTWADVENLNSQNE-----------------AELRRQFEERQQET 98 LK+E+ K+ +K +V +L +NE +R +ER+ E Sbjct: 1126 GGLKQEIMTLKEEQNKMQKEVNDLLQENEQLMKVMKTKHECQNLESEPIRNSVKERESER 1185 Query: 99 EHV------------YELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKG 146 L QL+Q E+ L E + E EKEC + ++G Sbjct: 1186 NQCNFKPQMDLEVKEISLDSYNAQLVQLEAMLRNKELKLQES--EKEKECLQHELQTIRG 1243 Query: 147 --VTKNWEDVPGDQV 159 T N +D+ ++ Sbjct: 1244 DLETSNLQDMQSQEI 1258 Score = 31.6 bits (70), Expect = 0.36 Identities = 32/143 (22%), Positives = 68/143 (47%), Gaps = 12/143 (8%) Query: 2 SNGYRTLSQHLN----DLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVES 57 S Y L Q L DL + + + LE+++++K + +E++ ++ ++ Sbjct: 354 STKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSF----QT 409 Query: 58 LKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQ--EE 115 L +E K L + +N+++ +AEL + +QQ ++ E + + Q + Sbjct: 410 LDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQA 469 Query: 116 SRLAKNEAARMAALVEAEKECNL 138 S++ +NE R ++ E +KE NL Sbjct: 470 SQIKENELRR--SMEEMKKENNL 490 Score = 28.1 bits (61), Expect = 4.0 Identities = 27/109 (24%), Positives = 51/109 (46%), Gaps = 5/109 (4%) Query: 8 LSQHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQ 67 LS+ L+ KKE S I L +R ++ + + N L E +L ++ + Sbjct: 947 LSETLSLEKKEMSS----IISLNKREIEELTQENGTLKEINASLNQEKMNLIQKSESFAN 1002 Query: 68 HLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEES 116 ++D+ + L+ Q + E + +R +ET + YE L K + QE++ Sbjct: 1003 YIDEREKSISELSDQYKQE-KLILLQRCEETGNAYEDLSQKYKAAQEKN 1050 >gi|148746195 trichohyalin [Homo sapiens] Length = 1943 Score = 46.2 bits (108), Expect = 1e-05 Identities = 41/143 (28%), Positives = 67/143 (46%), Gaps = 19/143 (13%) Query: 30 EERMQQKYEASR-EDIYKRNIE-----LKVEVESLKRELQDKKQHLDKT--------WAD 75 EER +QK+E R E KR E LK E E+ + E + +KQ L + W Sbjct: 431 EERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLK 490 Query: 76 VEN-----LNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALV 130 +E + E +LRR+ EER+++ E E Q L+ E +L + + R L+ Sbjct: 491 LEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLL 550 Query: 131 EAEKECNLELSEKLKGVTKNWED 153 + E+E LE + + + + E+ Sbjct: 551 KREEEKRLEQERREQRLKREQEE 573 Score = 44.7 bits (104), Expect = 4e-05 Identities = 33/104 (31%), Positives = 54/104 (51%), Gaps = 7/104 (6%) Query: 29 LEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKK--QHLDKTWADVENLNSQNEAE 86 L E +++ RE + EL+ E E L RE ++K+ Q L++ + + E + + E Sbjct: 1094 LREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQL 1153 Query: 87 LRRQFEERQ-QETEHVY----ELLENKIQLLQEESRLAKNEAAR 125 LR + E+R+ QE E Y EL + + QLL+EE + E R Sbjct: 1154 LREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERER 1197 Score = 42.4 bits (98), Expect = 2e-04 Identities = 37/146 (25%), Positives = 69/146 (47%), Gaps = 5/146 (3%) Query: 29 LEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKK--QHLDKTWADVENLNSQNEAE 86 L E +++ E Y+ E++ E E L RE +K+ Q L++ + + E L + E Sbjct: 1124 LREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQL 1183 Query: 87 LRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKG 146 LR + E+R+QE E Y E + +++ +++ + + E EKE N K+ Sbjct: 1184 LREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKE-NAVRDNKV-- 1240 Query: 147 VTKNWEDVPGDQVKPDQYTEALAQRD 172 K E+ Q++ Q + +Q+D Sbjct: 1241 YCKGRENEQFRQLEDSQLRDRQSQQD 1266 Score = 40.4 bits (93), Expect = 8e-04 Identities = 30/94 (31%), Positives = 51/94 (54%), Gaps = 7/94 (7%) Query: 29 LEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKK--QHLDKTWADVENLNSQNEAE 86 L E +++ RE Y+++ +L+ + E L E +K+ Q +K + + E L + E Sbjct: 944 LREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQL 1003 Query: 87 LRRQFEERQ-QETEHVY----ELLENKIQLLQEE 115 LR + E+R+ QE E Y EL + + QLL+EE Sbjct: 1004 LREEREKRRRQEWERQYRKKDELQQEEEQLLREE 1037 Score = 40.4 bits (93), Expect = 8e-04 Identities = 28/101 (27%), Positives = 50/101 (49%), Gaps = 7/101 (6%) Query: 29 LEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKK--QHLDKTWADVENLNSQNEAE 86 L E +++ RE Y+ EL+ E E L RE ++K+ Q ++ + + L + E Sbjct: 974 LGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQL 1033 Query: 87 LR-----RQFEERQQETEHVYELLENKIQLLQEESRLAKNE 122 LR R+ +ER+++ EL + + QLL EE + + Sbjct: 1034 LREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQ 1074 Score = 40.4 bits (93), Expect = 8e-04 Identities = 36/137 (26%), Positives = 64/137 (46%), Gaps = 10/137 (7%) Query: 16 KKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQD--KKQHLDKTW 73 KK+ + EER +++ + RE Y+ EL+ E E L E ++ ++Q L++ + Sbjct: 1022 KKDELQQEEEQLLREEREKRRLQ-ERERQYREEEELQQEEEQLLGEERETRRRQELERQY 1080 Query: 74 ADVENLNSQNEAELR-----RQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAA 128 E L + E LR R+ +ER+++ EL + + QLL+EE K + Sbjct: 1081 RKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREERE--KRRRQELER 1138 Query: 129 LVEAEKECNLELSEKLK 145 E+E E + L+ Sbjct: 1139 QYREEEEVQQEEEQLLR 1155 Score = 39.3 bits (90), Expect = 0.002 Identities = 41/149 (27%), Positives = 68/149 (45%), Gaps = 21/149 (14%) Query: 16 KKENFSLKLRIYFLEERMQQKYEA---------SREDI---YKRNIELKVEVESLKRELQ 63 +K + R Y EE +QQ+ E R+++ Y++ EL+ E E L RE Sbjct: 1039 EKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEP 1098 Query: 64 DKK--QHLDKTWADVENLNSQNEAELRRQFEERQ-QETEHVY----ELLENKIQLLQEES 116 +K+ Q ++ + E L + E LR + E+R+ QE E Y E+ + + QLL+EE Sbjct: 1099 EKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEP 1158 Query: 117 RLAKNEAARMAALVEAEKECNLELSEKLK 145 K + E+E E + L+ Sbjct: 1159 E--KRRRQELERQYREEEELQQEEEQLLR 1185 Score = 38.9 bits (89), Expect = 0.002 Identities = 36/154 (23%), Positives = 73/154 (47%), Gaps = 25/154 (16%) Query: 30 EERMQQKYEASREDIYKRNIELKVEVES----LKRELQDKKQHLDKTWADVENLNSQNEA 85 E++++++ E RE + KR E ++E E LKRE ++++ L K E Sbjct: 535 EQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLK-----------REE 583 Query: 86 ELRRQFEERQQETEHVYELLENKIQLLQEESRLAKN------EAARMAALVEAEKECNLE 139 E R+Q +R+QE L +++ L++E R + E R L+++E+ + Sbjct: 584 ERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEE----Q 639 Query: 140 LSEKLKGVTKNWEDVPGDQVKPDQYTEALAQRDK 173 + + + + ++ ++K ++ E L QR K Sbjct: 640 EERRQQQLRREQQERREQRLKREEEEERLEQRLK 673 Score = 38.5 bits (88), Expect = 0.003 Identities = 34/113 (30%), Positives = 56/113 (49%), Gaps = 4/113 (3%) Query: 6 RTLSQHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQ-D 64 R Q + ++E +LR EER +Q+ RE +R +L+ E + L+RE Q Sbjct: 346 RREQQLRREQEEERREQQLRREQEEERREQQLR--REQQLRREQQLRRE-QQLRREQQLR 402 Query: 65 KKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESR 117 ++Q L + + E +LRR+ EE + E +H E E +++ QEE R Sbjct: 403 REQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERR 455 Score = 38.1 bits (87), Expect = 0.004 Identities = 34/146 (23%), Positives = 71/146 (48%), Gaps = 5/146 (3%) Query: 29 LEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELR 88 L+ER +Q+ D ++ +E + ++ +RE Q + K + + L E +LR Sbjct: 1628 LQEREEQQLHRQERD--RKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLR 1685 Query: 89 RQFEERQ-QETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGV 147 RQ +R+ +E E E + + LQEE +L + E R E E+ E+L+ Sbjct: 1686 RQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELER--KFREEEQLRQETEQEQLRRQ 1743 Query: 148 TKNWEDVPGDQVKPDQYTEALAQRDK 173 + + + +Q++P++ + L ++++ Sbjct: 1744 ERYRKILEEEQLRPEREEQQLRRQER 1769 Score = 37.4 bits (85), Expect = 0.007 Identities = 38/145 (26%), Positives = 67/145 (46%), Gaps = 15/145 (10%) Query: 23 KLRIYFLEERMQQKYE-----ASREDIYKRNIELKVEVESLKRELQDKK--QHLDKTWAD 75 K R EER ++++ A +E + K L+ E E L+RE ++K+ Q ++ + + Sbjct: 873 KWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYRE 932 Query: 76 VENLNSQNEAELR-----RQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALV 130 E L + E LR R+ +ER+++ +L + + QLL EE + + Sbjct: 933 EEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYRE 992 Query: 131 EAE---KECNLELSEKLKGVTKNWE 152 E E +E L E+ K + WE Sbjct: 993 EEELQQEEEQLLREEREKRRRQEWE 1017 Score = 37.0 bits (84), Expect = 0.009 Identities = 32/120 (26%), Positives = 55/120 (45%), Gaps = 14/120 (11%) Query: 30 EERMQQKYEASR-EDIYKRNIELKVEVESLKRE--LQDKKQHLDKTWADVENLNSQNEAE 86 +ER++Q+ R E+++++ E + E E LQ K H + + D E L + E Sbjct: 158 QERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLE 217 Query: 87 LRRQFEERQQET-----------EHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKE 135 LRR+ E +Q+ E E + + L +EE +L + E R L E E++ Sbjct: 218 LRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQ 277 Score = 34.7 bits (78), Expect = 0.042 Identities = 25/94 (26%), Positives = 51/94 (54%), Gaps = 9/94 (9%) Query: 30 EERMQQKYEASREDIYKRNIEL-KVEVESLKRELQDKKQHLDKTWADVENLNSQNEA--- 85 EE++Q++ + ++ + +L K+E + L+RE Q+++Q + + + Q E Sbjct: 257 EEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERRE 316 Query: 86 --ELRRQFEERQQETEHVYELLENKIQLLQEESR 117 E RR+ +ER+++ E E E +++ QEE R Sbjct: 317 QQEERREQQERREQQE---ERREQQLRREQEERR 347 Score = 34.7 bits (78), Expect = 0.042 Identities = 26/117 (22%), Positives = 54/117 (46%), Gaps = 3/117 (2%) Query: 29 LEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELR 88 L+E +Q + R+++ + E + + + L+RE Q +++ ++ E Q E R Sbjct: 271 LQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQE---R 327 Query: 89 RQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLK 145 R+ +E ++E + E E + Q L+ E + E E +E L ++L+ Sbjct: 328 REQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLR 384 Score = 34.3 bits (77), Expect = 0.055 Identities = 33/119 (27%), Positives = 54/119 (45%), Gaps = 27/119 (22%) Query: 22 LKLRIYFLEERMQQK--------YEASREDIYKRNIELKVEVESLK-------RELQDKK 66 L+LR EE+ QQ+ E ++ KR L+ E E L+ RELQ+++ Sbjct: 216 LELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEE 275 Query: 67 QHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAAR 125 + L K ELRR+ +E +Q+ + + E +++ QEE R + E R Sbjct: 276 EQLRKL----------ERQELRRERQEEEQQQQRLRR--EQQLRRKQEEERREQQEERR 322 Score = 34.3 bits (77), Expect = 0.055 Identities = 39/149 (26%), Positives = 73/149 (48%), Gaps = 22/149 (14%) Query: 30 EERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRR 89 E++++++ + RE +R +L+ E + L+RE Q++++H K + + E L+R Sbjct: 398 EQQLRREQQLRREQQLRREQQLRRE-QQLRRE-QEEERHEQK------HEQERREQRLKR 449 Query: 90 QFEE------RQQETE-HVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSE 142 + EE R++ETE H E + +++ QEE R R L E E+ E E Sbjct: 450 EQEERRDWLKREEETERHEQERRKQQLKRDQEEER-----RERWLKLEEEERREQQERRE 504 Query: 143 KLKGVTKNWEDVPGDQVKPDQYTEALAQR 171 + + + E+ ++K + E L QR Sbjct: 505 --QQLRREQEERREQRLKRQEEEERLQQR 531 Score = 33.9 bits (76), Expect = 0.072 Identities = 32/125 (25%), Positives = 60/125 (48%), Gaps = 12/125 (9%) Query: 30 EERMQQKYEASREDIYKRNIE-------LKVEVESLKRELQDKKQHLDKTWADVENLNSQ 82 E++++++ E RE KR E L+ E + L+RE +++++ L K + + Sbjct: 504 EQQLRREQEERREQRLKRQEEEERLQQRLRSE-QQLRREQEERREQLLKREEEKRLEQER 562 Query: 83 NEAELRRQFEERQ-QETEHVYELLENKIQLLQE---ESRLAKNEAARMAALVEAEKECNL 138 E L+R+ EER+ Q + E + +++ QE E RL + E R+ E+ Sbjct: 563 REQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKR 622 Query: 139 ELSEK 143 E E+ Sbjct: 623 EEPEE 627 Score = 32.0 bits (71), Expect = 0.27 Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 2/97 (2%) Query: 28 FLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKK-QHLDKTWADVENLNSQNEAE 86 FLEE Q + E R+ + + + E + L R+ +D+K ++ E E E Sbjct: 1448 FLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQE 1507 Query: 87 LRRQFEERQ-QETEHVYELLENKIQLLQEESRLAKNE 122 LR Q ER+ E E + + + LQEE +L + E Sbjct: 1508 LRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQE 1544 Score = 29.3 bits (64), Expect = 1.8 Identities = 27/101 (26%), Positives = 48/101 (47%), Gaps = 3/101 (2%) Query: 27 YFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLD-KTWADVENLNSQNEA 85 + L E+ ++ E R +R+ E E L+RE Q + + D K+ + + L + E Sbjct: 1269 HLLGEQQERDREQERRRWQQRDRHFPEE-EQLEREEQKEAKRRDRKSQEEKQLLREEREE 1327 Query: 86 ELRRQFEERQ-QETEHVYELLENKIQLLQEESRLAKNEAAR 125 + RRQ +R+ +E E + + E + QE R + E R Sbjct: 1328 KRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELR 1368 Score = 28.9 bits (63), Expect = 2.3 Identities = 25/91 (27%), Positives = 44/91 (48%), Gaps = 6/91 (6%) Query: 15 LKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKREL--QDKKQHLDKT 72 LK+E+ + EE +Q E + I K +L+ E ++ + ++ + +KQ + Sbjct: 672 LKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRR 731 Query: 73 WADVENLNSQNEAELRRQFEER----QQETE 99 + E + E+EL+ Q EER QQE E Sbjct: 732 RQEQEEKRRRRESELQWQEEERAHRQQQEEE 762 Score = 28.5 bits (62), Expect = 3.0 Identities = 28/145 (19%), Positives = 62/145 (42%), Gaps = 15/145 (10%) Query: 31 ERMQQKYEASREDIYKRNIELKVEVESLKRELQDK--KQHLDKTWADVENLNSQNEAELR 88 E + + R ++ + + + E + +RE QD+ ++ +K W E + + E +L+ Sbjct: 202 EEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQ 261 Query: 89 RQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVT 148 + +RQ+E L +EE +L K E + + E++ L + + Sbjct: 262 EEEPQRQRE-------------LQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRR 308 Query: 149 KNWEDVPGDQVKPDQYTEALAQRDK 173 K E+ Q + + E Q+++ Sbjct: 309 KQEEERREQQEERREQQERREQQEE 333 Score = 27.7 bits (60), Expect = 5.2 Identities = 26/122 (21%), Positives = 53/122 (43%), Gaps = 7/122 (5%) Query: 29 LEERMQQKYEASREDIYKRNIELKVEVES---LKRELQDKKQHLDKTWADVENLN--SQN 83 L+ER +Q D R EL+ + + L+ E + ++Q ++ + E + Sbjct: 1345 LQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQER 1404 Query: 84 EAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEK 143 E +LR+ + + +E E E + +EE ++ + E R +E E++ E K Sbjct: 1405 EQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERER--KFLEEEQQLRQERHRK 1462 Query: 144 LK 145 + Sbjct: 1463 FR 1464 Score = 27.3 bits (59), Expect = 6.7 Identities = 32/150 (21%), Positives = 66/150 (44%), Gaps = 14/150 (9%) Query: 25 RIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNE 84 R + EE+ ++ E R+ + + + E E L+R+ + K + + + E Sbjct: 1707 RKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQ-----ERYRKILEEEQLRPEREE 1761 Query: 85 AELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKL 144 +LRRQ +R+ E + QL +ES E ++ E E++ +L + Sbjct: 1762 QQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQ--EREEQ---QLRPQQ 1816 Query: 145 KGVTKNWEDVPGDQVKPDQYTEALAQ-RDK 173 + WE+ +Q++ ++ + L Q RD+ Sbjct: 1817 RDGKYRWEE---EQLQLEEQEQRLRQERDR 1843 Score = 26.9 bits (58), Expect = 8.8 Identities = 20/105 (19%), Positives = 51/105 (48%), Gaps = 4/105 (3%) Query: 22 LKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLN- 80 +K RI + +++ + +A + +Y R + + + ++E + +++ + W + E + Sbjct: 697 IKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHR 756 Query: 81 SQNEAELRRQFE---ERQQETEHVYELLENKIQLLQEESRLAKNE 122 Q E E RR F + ++++E + L + L ++ R + E Sbjct: 757 QQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAE 801 Score = 26.9 bits (58), Expect = 8.8 Identities = 24/123 (19%), Positives = 49/123 (39%), Gaps = 1/123 (0%) Query: 30 EERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRR 89 EE+ + E+ R+ + + + E + L+ + +D K ++ +E + E R Sbjct: 1784 EEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDR 1843 Query: 90 QFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTK 149 Q+ +Q E + +L QEE + + E R ++ E + G K Sbjct: 1844 QYRAEEQFATQEKSRREEQ-ELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIK 1902 Query: 150 NWE 152 + E Sbjct: 1903 SQE 1905 >gi|190341068 forkhead-associated (FHA) phosphopeptide binding domain 1 [Homo sapiens] Length = 1412 Score = 44.7 bits (104), Expect = 4e-05 Identities = 29/117 (24%), Positives = 61/117 (52%), Gaps = 4/117 (3%) Query: 6 RTLSQHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDK 65 ++++Q N +K+ + R+ LEER+ ++ E I + K +ES KR++QD Sbjct: 728 KSITQEKNRVKEALEEEQTRVQELEERLARQKEVLESSIAHEKRKAKEALESEKRKVQDL 787 Query: 66 KQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNE 122 + HL + + ++ N A +R+ +E ++ + + LEN++ +EE L + + Sbjct: 788 ENHLTQQ----KEISESNIAYEKRKAKEAMEKEKKKVQDLENRLTKQKEELELKEQK 840 >gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo sapiens] Length = 1935 Score = 44.3 bits (103), Expect = 5e-05 Identities = 33/148 (22%), Positives = 72/148 (48%), Gaps = 8/148 (5%) Query: 1 MSNGYRTLSQHLNDLKKENFSLKLRIYFLEERMQ------QKYEASREDIYKRNIELKVE 54 + N Y +HL K+EN +L+ I L E++ + E R+ + +EL+ Sbjct: 1484 LKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSA 1543 Query: 55 VESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQE 114 +E + L+ ++ + + + + ++ E +L + EE +Q + ++++ L Sbjct: 1544 LEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDA 1603 Query: 115 ESRLAKNEAARMAALVEAE-KECNLELS 141 E+R ++NEA R+ +E + E ++LS Sbjct: 1604 ETR-SRNEALRVKKKMEGDLNEMEIQLS 1630 Score = 36.6 bits (83), Expect = 0.011 Identities = 37/149 (24%), Positives = 68/149 (45%), Gaps = 18/149 (12%) Query: 12 LNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDK 71 L+D + N LK I +E R +A E EL+ VE +R + +Q L + Sbjct: 1657 LDDAVRANDDLKENIAIVERR-NNLLQAELE-------ELRAVVEQTERSRKLAEQELIE 1708 Query: 72 TWADVENLNSQNEAELRRQ------FEERQQETEHVYELLENKIQLLQEESRLAKNEAAR 125 T V+ L+SQN + + ++ + Q E E + N +E+++ A +AA Sbjct: 1709 TSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRN----AEEKAKKAITDAAM 1764 Query: 126 MAALVEAEKECNLELSEKLKGVTKNWEDV 154 MA ++ E++ + L K + + +D+ Sbjct: 1765 MAEELKKEQDTSAHLERMKKNMEQTIKDL 1793 Score = 31.6 bits (70), Expect = 0.36 Identities = 29/113 (25%), Positives = 49/113 (43%), Gaps = 31/113 (27%) Query: 47 RNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLE 106 ++ E + E+ S+K E K+ L+K+ E RR+ EL E Sbjct: 841 KSAEREKEMASMKEEFTRLKEALEKS-------------EARRK------------ELEE 875 Query: 107 NKIQLLQEESRLAKNEAARMAALVEAEKECN------LELSEKLKGVTKNWED 153 + LLQE++ L A L +AE+ C+ ++L K+K + + ED Sbjct: 876 KMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLED 928 Score = 31.6 bits (70), Expect = 0.36 Identities = 35/154 (22%), Positives = 62/154 (40%), Gaps = 10/154 (6%) Query: 3 NGYRTLSQHLNDLKKENFSLKLRIYFLEERMQQKYE--ASREDIYKRNIELKVEVESLKR 60 N + L++ + L + L L+E QQ + + ED + KV++E Sbjct: 973 NKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVD 1032 Query: 61 ELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAK 120 +L+ + K D+E + E +L+ E LEN Q L E + Sbjct: 1033 DLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMD--------LENDKQQLDERLKKKD 1084 Query: 121 NEAARMAALVEAEKECNLELSEKLKGVTKNWEDV 154 E + A +E E+ +L +KLK + E++ Sbjct: 1085 FELNALNARIEDEQALGSQLQKKLKELQARIEEL 1118 Score = 31.6 bits (70), Expect = 0.36 Identities = 30/130 (23%), Positives = 61/130 (46%), Gaps = 10/130 (7%) Query: 30 EERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEA--EL 87 ++++ Q+ + + E + N + +E K LQ++ + L DVE N+ A + Sbjct: 1390 KKKLAQRLQEAEEAVEAVNAKCS-SLEKTKHRLQNEIEDL---MVDVERSNAAAAALDKK 1445 Query: 88 RRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGV 147 +R F++ E + YE +++++ Q+E+R E ++ E +LE E K Sbjct: 1446 QRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEE----SLEHLETFKRE 1501 Query: 148 TKNWEDVPGD 157 KN ++ D Sbjct: 1502 NKNLQEEISD 1511 Score = 30.4 bits (67), Expect = 0.80 Identities = 35/148 (23%), Positives = 66/148 (44%), Gaps = 9/148 (6%) Query: 7 TLSQHLNDLKKENFSLKLRIYFLEERMQQ------KYEASREDIYKR---NIELKVEVES 57 +L Q NDL+ + + + + EER Q + EA +++ +R E+ E+ + Sbjct: 879 SLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTA 938 Query: 58 LKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESR 117 KR+L+D+ L + D+E ++ E E + + TE + L E +L +E+ Sbjct: 939 KKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKA 998 Query: 118 LAKNEAARMAALVEAEKECNLELSEKLK 145 L + + L E + N K+K Sbjct: 999 LQEAHQQALDDLQAEEDKVNTLTKAKVK 1026 Score = 28.5 bits (62), Expect = 3.0 Identities = 25/122 (20%), Positives = 55/122 (45%), Gaps = 4/122 (3%) Query: 15 LKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWA 74 ++K L + + ER+++ A+ I + N + + E + ++R+L++ + T A Sbjct: 1132 VEKLRSDLSRELEEISERLEEAGGATSVQI-EMNKKREAEFQKMRRDLEEATLQHEATAA 1190 Query: 75 DVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEK 134 + ++ + AEL Q + Q+ + +L + K + E + N + A EK Sbjct: 1191 ALRKKHADSVAELGEQIDNLQRVKQ---KLEKEKSEFKLELDDVTSNMEQIIKAKANLEK 1247 Query: 135 EC 136 C Sbjct: 1248 MC 1249 >gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with transmembrane signal), 1 [Homo sapiens] Length = 3259 Score = 44.3 bits (103), Expect = 5e-05 Identities = 40/155 (25%), Positives = 73/155 (47%), Gaps = 9/155 (5%) Query: 17 KENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADV 76 KE ++ R+ L+E + K + N L ESLK L+ + +K ++ Sbjct: 1532 KEKDTVLGRLALLQEE-RDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEI 1590 Query: 77 ENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKEC 136 E+L S AE +++E+ +E + YE+L LQ ++ NEA R+ +VEA ++ Sbjct: 1591 ESLKSSKIAE-STEWQEKHKELQKEYEIL------LQSYENVS-NEAERIQHVVEAVRQE 1642 Query: 137 NLELSEKLKGVTKNWEDVPGDQVKPDQYTEALAQR 171 EL KL+ N ++ + +Q E + ++ Sbjct: 1643 KQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEK 1677 Score = 41.6 bits (96), Expect = 3e-04 Identities = 40/163 (24%), Positives = 74/163 (45%), Gaps = 27/163 (16%) Query: 6 RTLSQHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDK 65 R L H++DL EN L + E + Q ++ K+ +E++++ +EL++K Sbjct: 2513 RGLRSHMDDLNSENAKLDAELIQYREDLNQVI-TIKDSQQKQLLEVQLQ---QNKELENK 2568 Query: 66 KQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLEN----------KIQLLQEE 115 L++ + E N +LRR F Q+E + + + +E+ ++ LQEE Sbjct: 2569 YAKLEEKLKESEEANE----DLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEE 2624 Query: 116 SRLA---------KNEAARMAALVEAEKECNLELSEKLKGVTK 149 L + E R++AL + ++ EL E+L V K Sbjct: 2625 GTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQK 2667 Score = 39.3 bits (90), Expect = 0.002 Identities = 31/138 (22%), Positives = 69/138 (50%), Gaps = 11/138 (7%) Query: 7 TLSQHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKK 66 +L++++ ++K + ++ L Q + + S+ D K + E ++E+E +K +LQ+K+ Sbjct: 106 SLNKYIEEMKAQGGTV------LPTEPQSEEQLSKHD--KSSTEEEMEIEKIKHKLQEKE 157 Query: 67 QHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARM 126 + + A + ++ A+ + EE + + E E I LQ ++L++ +A + Sbjct: 158 ELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQE-KEEFISTLQ--AQLSQTQAEQA 214 Query: 127 AALVEAEKECNLELSEKL 144 A V EK+ E +L Sbjct: 215 AQQVVREKDARFETQVRL 232 Score = 37.7 bits (86), Expect = 0.005 Identities = 32/147 (21%), Positives = 70/147 (47%), Gaps = 5/147 (3%) Query: 17 KENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADV 76 ++N L+ + LEE++++ EA+ ED+ + L+ E + L +E++ K + + V Sbjct: 2560 QQNKELENKYAKLEEKLKESEEAN-EDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQV 2618 Query: 77 ENLNSQNEAEL-RRQFEERQQETEHVYELL---ENKIQLLQEESRLAKNEAARMAALVEA 132 L + L Q + +++E + L + +I L+EE + EAA+ +E Sbjct: 2619 TALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIED 2678 Query: 133 EKECNLELSEKLKGVTKNWEDVPGDQV 159 + + L+ G+ +N + ++V Sbjct: 2679 KLKKELKHLHHDAGIMRNETETAEERV 2705 Score = 35.4 bits (80), Expect = 0.025 Identities = 41/191 (21%), Positives = 83/191 (43%), Gaps = 43/191 (22%) Query: 8 LSQHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKK- 66 L++ ++ L E S ++I L+ + +D+ + E + SL+ +LQ+K+ Sbjct: 794 LTEQIHSLSIEAKSKDVKIEVLQNEL--------DDVQLQFSEQSTLIRSLQSQLQNKES 845 Query: 67 ---------QHLDKTWADVENLNSQNEAE-----------------LRRQFEER-QQETE 99 +H+ ++ SQ E E L++ EE+ QQ TE Sbjct: 846 EVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTE 905 Query: 100 HVYELLENKIQLLQE------ESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWED 153 + + E +QL +E E + K + ++ EA+KE E +E G+ +N+++ Sbjct: 906 ISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDE 965 Query: 154 V-PGDQVKPDQ 163 + P Q+ ++ Sbjct: 966 MSPAGQISKEE 976 Score = 35.4 bits (80), Expect = 0.025 Identities = 26/131 (19%), Positives = 64/131 (48%), Gaps = 11/131 (8%) Query: 28 FLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAEL 87 F E+++ +ASRE + + E+ ++ + + L K++ + A EL Sbjct: 2354 FSYEQLETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQVAIA-----------EL 2402 Query: 88 RRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGV 147 R+Q ++ +E E++ E + +L+EE++ A ++ ++ ++ K+ N++ +L Sbjct: 2403 RQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSF 2462 Query: 148 TKNWEDVPGDQ 158 K+ + D+ Sbjct: 2463 VKSMSSLQNDR 2473 Score = 35.0 bits (79), Expect = 0.032 Identities = 39/153 (25%), Positives = 69/153 (45%), Gaps = 28/153 (18%) Query: 7 TLSQHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKK 66 ++++ + L +E FSL + I L+E++ A E+ K +E EV S Sbjct: 909 SMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRA--EEAKKEQVEEDNEVSS--------- 957 Query: 67 QHLDKTWADVENLNSQNEAELRRQFE----ERQQETEHVYELLENKIQLLQEESRL---- 118 L + + ++ ++ EL+ +F+ E +Q + L N+ +LLQ SRL Sbjct: 958 -GLKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEEL 1016 Query: 119 --AKNEAARMAALVEAEK------ECNLELSEK 143 K+E+ + L E E+ + N E SEK Sbjct: 1017 ANLKDESKKEIPLSETERGEVEEDKENKEYSEK 1049 Score = 34.7 bits (78), Expect = 0.042 Identities = 33/149 (22%), Positives = 65/149 (43%), Gaps = 10/149 (6%) Query: 1 MSNGYRTLSQHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKR 60 + + L + DL KE SLK+ I L ++ E +Y + +LKV+ E + R Sbjct: 2586 LRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLY--HAQLKVKEEEVHR 2643 Query: 61 ELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAK 120 L ++ + ++ E EL +E ++ + + L+ +++ L ++ + + Sbjct: 2644 --------LSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMR 2695 Query: 121 NEAARMAALVEAEKECNLELSEKLKGVTK 149 NE V +E+ +KL VTK Sbjct: 2696 NETETAEERVAELARDLVEMEQKLLMVTK 2724 Score = 32.7 bits (73), Expect = 0.16 Identities = 32/173 (18%), Positives = 70/173 (40%), Gaps = 18/173 (10%) Query: 8 LSQHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQ 67 LSQ L ++ E+ +L+ + E + E ++ +R K+ +L+ E+ + Sbjct: 292 LSQQLQQMEAEHNTLRNTVETEREESKILLEKMELEVAER----KLSFHNLQEEMHHLLE 347 Query: 68 HLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELL--------------ENKIQLLQ 113 ++ L S+ A ++ E +++T H+ L + +LLQ Sbjct: 348 QFEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQ 407 Query: 114 EESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTE 166 +++ A A + L + ++ + E+S+ L + + PD Y E Sbjct: 408 DKNEQAVQSAQTIQQLEDQLQQKSKEISQFLNRLPLQQHETASQTSFPDVYNE 460 Score = 30.8 bits (68), Expect = 0.61 Identities = 24/90 (26%), Positives = 48/90 (53%), Gaps = 10/90 (11%) Query: 29 LEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNE--AE 86 LEE++ E +E + K+ E +++ ++ Q+K++HL E L Q + Sbjct: 1162 LEEKILA-LEKEKEQLQKKLQEALTSRKAILKKAQEKERHLR------EELKQQKDDYNR 1214 Query: 87 LRRQFEERQQETEHVYELLENKIQLLQEES 116 L+ QF+E+ +E E++ + L ++Q+ ES Sbjct: 1215 LQEQFDEQSKENENIGDQL-RQLQIQVRES 1243 Score = 28.9 bits (63), Expect = 2.3 Identities = 28/121 (23%), Positives = 54/121 (44%), Gaps = 25/121 (20%) Query: 43 DIYKRNIELKVEVESLKR---ELQDKKQHLDKTWADVENL-----------------NSQ 82 D +N L+ E+++LK+ EL+++KQ L K VE+ N Sbjct: 1946 DAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKS 2005 Query: 83 NEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSE 142 + EL+ +E+QQE + + K + +E A + V+ E + +LE+++ Sbjct: 2006 HAKELQELLKEKQQEVKQL-----QKDCIRYQEKISALERTVKALEFVQTESQKDLEITK 2060 Query: 143 K 143 + Sbjct: 2061 E 2061 Score = 28.9 bits (63), Expect = 2.3 Identities = 33/132 (25%), Positives = 60/132 (45%), Gaps = 21/132 (15%) Query: 50 ELKVEVESLKRELQDKKQHLDKTWADVE-------NLNSQNEAELRRQFEERQQETEHVY 102 ELK+ + L+ DK+ K +V+ L +N+ EL Q EE T H+Y Sbjct: 2249 ELKINISRLEH---DKQIWESKAQTEVQLQQKVCDTLQGENK-ELLSQLEE----TRHLY 2300 Query: 103 ELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWE-DVPGDQVKP 161 +N++ L+ E + K++ ++ +E K E L+G+ + E D+ + Sbjct: 2301 HSSQNELAKLESELKSLKDQLTDLSNSLEKCK----EQKGNLEGIIRQQEADIQNSKFSY 2356 Query: 162 DQY-TEALAQRD 172 +Q T+ A R+ Sbjct: 2357 EQLETDLQASRE 2368 Score = 28.5 bits (62), Expect = 3.0 Identities = 29/155 (18%), Positives = 71/155 (45%), Gaps = 19/155 (12%) Query: 18 ENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDK-------KQHLD 70 +N LK + +E ++ + + ED+ +R + + + K+ +Q+K K HL+ Sbjct: 2097 DNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLE 2156 Query: 71 KTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMA--- 127 +T +++ ++ + E+ +Q +E T + LQ++ +EA + Sbjct: 2157 ETIGEIQVTLNKKDKEV-QQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKF 2215 Query: 128 --ALVEAEKECNLE------LSEKLKGVTKNWEDV 154 A+ E+E L+ L ++L+ ++ + E++ Sbjct: 2216 SDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEEL 2250 >gi|4885583 Rho-associated, coiled-coil containing protein kinase 1 [Homo sapiens] Length = 1354 Score = 43.9 bits (102), Expect = 7e-05 Identities = 49/177 (27%), Positives = 84/177 (47%), Gaps = 28/177 (15%) Query: 1 MSNGYRTLSQHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKV------- 53 + N TL L DLKK + + +L L + +Q EA+ D+ + + V Sbjct: 512 VENEVSTLKDQLEDLKKVSQNSQLANEKLSQLQKQLEEAN--DLLRTESDTAVRLRKSHT 569 Query: 54 -------EVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLE 106 ++ESL RELQ++ + L+ + + + Q +A L + +R ++E + + L+ Sbjct: 570 EMSKSISQLESLNRELQERNRILENSKSQTDKDYYQLQAILEAERRDRGHDSEMIGD-LQ 628 Query: 107 NKIQLLQEESR-----LAKNEAARMAA---LVEAEKECN---LELSEKLKGVTKNWE 152 +I LQEE + L K E R A L +EKE N ++L+ KLK + + E Sbjct: 629 ARITSLQEEVKHLKHNLEKVEGERKEAQDMLNHSEKEKNNLEIDLNYKLKSLQQRLE 685 Score = 28.5 bits (62), Expect = 3.0 Identities = 36/151 (23%), Positives = 66/151 (43%), Gaps = 16/151 (10%) Query: 13 NDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEV--------ESLKRELQD 64 N+LK + F + LE++M+Q+ E KR +E ++ E RELQD Sbjct: 788 NELKTQAFEAD-NLKGLEKQMKQEINTLLEA--KRLLEFELAQLTKQYRGNEGQMRELQD 844 Query: 65 KKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAA 124 + + L EL+ + EE+ +E + L+N+ + L + LA+ +A Sbjct: 845 QLEAEQY----FSTLYKTQVKELKEEIEEKNRENLKKIQELQNEKETLATQLDLAETKAE 900 Query: 125 RMAALVEAEKECNLELS-EKLKGVTKNWEDV 154 +E EL+ E K ++N +++ Sbjct: 901 SEQLARGLLEEQYFELTQESKKAASRNRQEI 931 >gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] Length = 1411 Score = 43.9 bits (102), Expect = 7e-05 Identities = 41/171 (23%), Positives = 81/171 (47%), Gaps = 26/171 (15%) Query: 8 LSQHLNDLKKENFSLKLRIYFLEERMQQ------KYEASRE----DIYKR---NIELKVE 54 L HL + K++ SL+ + LE ++++ + +AS+E D+ ++ N +L++ Sbjct: 707 LESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELR 766 Query: 55 VESLKRELQDKKQHLDKTWADVEN-----------LNSQNEAE--LRRQFEERQQETEHV 101 L ++L+ +K+ + T D++ L Q E + L++ FE QET+ Sbjct: 767 ATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQ 826 Query: 102 YELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWE 152 +E L N+IQ E + K E + + K+ ++S+ LK +E Sbjct: 827 HEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFE 877 Score = 37.0 bits (84), Expect = 0.009 Identities = 33/155 (21%), Positives = 72/155 (46%), Gaps = 15/155 (9%) Query: 8 LSQHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQ 67 L+ LN+ K++ L ++I E + A + +L+ +++ + LQDK+Q Sbjct: 626 LNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTA----QRADLQNHLDTAQNALQDKQQ 681 Query: 68 HLDKTWADVENLN----------SQNEAELRRQFEERQQETEHVYELLENKIQLLQEESR 117 L+K ++ + SQ E+ L ++++E+ E E LE +I+ L+ +S Sbjct: 682 ELNKITTQLDQVTAKLQDKQEHCSQLESHL-KEYKEKYLSLEQKTEELEGQIKKLEADSL 740 Query: 118 LAKNEAARMAALVEAEKECNLELSEKLKGVTKNWE 152 K + ++ +++ N +L + ++K E Sbjct: 741 EVKASKEQALQDLQQQRQLNTDLELRATELSKQLE 775 Score = 34.7 bits (78), Expect = 0.042 Identities = 19/81 (23%), Positives = 47/81 (58%), Gaps = 1/81 (1%) Query: 5 YRTLSQHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQD 64 +++ + +++L+K+ L+ I LE +Q + R + +R ++ + E+E L+ ++ + Sbjct: 1257 WQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQD-ERRALLERCLKGEGEIEKLQTKVLE 1315 Query: 65 KKQHLDKTWADVENLNSQNEA 85 ++ LD T A V+ L +N++ Sbjct: 1316 LQRKLDNTTAAVQELGRENQS 1336 Score = 29.6 bits (65), Expect = 1.4 Identities = 42/189 (22%), Positives = 74/189 (39%), Gaps = 28/189 (14%) Query: 11 HLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLD 70 +L D K+ KL + + ++ E + + ++K E E LK+E +K+ L Sbjct: 1160 NLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEELKKEFIEKEAKLH 1219 Query: 71 KTWADVE---NLNSQNEAELRRQF-----------EERQQETEHVYEL------------ 104 + E + +NEA+L Q +E Q V EL Sbjct: 1220 SEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKKEWQSSQRRVSELEKQTDDLRGEIA 1279 Query: 105 -LENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGD-QVKPD 162 LE +Q Q+E R + +E + LEL KL T +++ + Q Sbjct: 1280 VLEATVQNNQDERRALLERCLKGEGEIEKLQTKVLELQRKLDNTTAAVQELGRENQSLQI 1339 Query: 163 QYTEALAQR 171 ++T+AL ++ Sbjct: 1340 KHTQALNRK 1348 >gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens] Length = 1233 Score = 43.5 bits (101), Expect = 9e-05 Identities = 34/139 (24%), Positives = 60/139 (43%), Gaps = 7/139 (5%) Query: 10 QHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHL 69 Q + +E + R LEE +KY +E+ KR L E+E R+ + + L Sbjct: 348 QEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRL 407 Query: 70 DKTWADVENLNSQNEAELR---RQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARM 126 D E + EA+++ R+ EE Q+ E + E + Q L+E+ +L + Sbjct: 408 DLE----ERKKVETEAKIKQKLREIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTEEV 463 Query: 127 AALVEAEKECNLELSEKLK 145 E N EL++ ++ Sbjct: 464 EMAKRRIDEINKELNQVME 482 Score = 36.2 bits (82), Expect = 0.015 Identities = 30/153 (19%), Positives = 71/153 (46%), Gaps = 19/153 (12%) Query: 16 KKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELK--------VEVESLKRELQDKKQ 67 +K+N + + + E+ +Y+ ++++ + ++L+ VE+E L +EL K + Sbjct: 188 RKKNIAAERKEAKQEKEEADRYQRLKDEVVRAQVQLQLFKLYHNEVEIEKLNKELASKNK 247 Query: 68 HLD---KTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAA 124 ++ K VE+ + + EL + E+QQ + + E ++++ + + AK + Sbjct: 248 EIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKE-KDSELNQKRPQYIKAKENTS 306 Query: 125 RMAALVEAEKECNLELSEKLKGVTKNWEDVPGD 157 +EA K + L+ K+++ GD Sbjct: 307 HKIKKLEAAK-------KSLQNAQKHYKKRKGD 332 Score = 35.0 bits (79), Expect = 0.032 Identities = 23/92 (25%), Positives = 52/92 (56%), Gaps = 2/92 (2%) Query: 15 LKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIEL-KVEVESLKRELQDKKQHLDKTW 73 L+ EN +L I E+ Q K + + ++++ ++ + E+E LK+E Q + +D+T Sbjct: 808 LEFENQKTRLGIQLDFEKNQLKEDQDKVHMWEQTVKKDENEIEKLKKEEQRHMKIIDETM 867 Query: 74 ADVENLNSQNEAELRRQFEERQQETEHVYELL 105 A +++L +Q+ A+ + + ++ E E + + L Sbjct: 868 AQLQDLKNQHLAK-KSEVNDKNHEMEEIRKKL 898 Score = 27.3 bits (59), Expect = 6.7 Identities = 23/82 (28%), Positives = 37/82 (45%), Gaps = 7/82 (8%) Query: 25 RIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNE 84 RI LEE + + S E+ K EL EVE KR + + + L++ + + Sbjct: 434 RIEKLEEYITTSKQ-SLEEQKKLEGELTEEVEMAKRRIDEINKELNQV------MEQLGD 486 Query: 85 AELRRQFEERQQETEHVYELLE 106 A + RQ RQQ + E ++ Sbjct: 487 ARIDRQESSRQQRKAEIMESIK 508 >gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] Length = 2230 Score = 43.5 bits (101), Expect = 9e-05 Identities = 35/154 (22%), Positives = 71/154 (46%), Gaps = 24/154 (15%) Query: 12 LNDLKKENFSLKLRIYFLEERMQQKYEASRE-----------DIYKRNIELKVEVESLKR 60 L DL++E + + RI LE +++ + ++ + K N E+ V VE K Sbjct: 555 LRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKT 614 Query: 61 ELQDKKQHLDKTWAD-VENLNSQNEAELRRQFEERQQETE------------HVYELLEN 107 EL+ K D W + ++ L Q + E+ + E+ +QE E H+ E+ E Sbjct: 615 ELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEK 674 Query: 108 KIQLLQEESRLAKNEAARMAALVEAEKECNLELS 141 ++ L + ++ ++ ++ +++A + ELS Sbjct: 675 TLEKLDVKQTELESLSSELSEVLKARHKLEEELS 708 Score = 39.3 bits (90), Expect = 0.002 Identities = 28/139 (20%), Positives = 72/139 (51%), Gaps = 3/139 (2%) Query: 7 TLSQHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDK- 65 +L Q L+ +K+E + + EE++ + + +++ ++ EL ++++ +RE Q++ Sbjct: 454 SLQQELSRVKQEVVDVMKKSS--EEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQM 511 Query: 66 KQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAAR 125 K L+K+ ++ ++ + E + EE + + + + ENK++ LQ+E+ + Sbjct: 512 KVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILE 571 Query: 126 MAALVEAEKECNLELSEKL 144 + + +E + N S+ L Sbjct: 572 LESSLEKSLQENKNQSKDL 590 Score = 38.5 bits (88), Expect = 0.003 Identities = 36/146 (24%), Positives = 66/146 (45%), Gaps = 24/146 (16%) Query: 10 QHLNDLKKENFSLKLRIYFLEERMQQKYEASREDI-YKRNIELKVEVESLKRELQDKKQH 68 Q L LKKE ++ ++K + +ED+ K N LK + +L K+Q Sbjct: 1962 QELEILKKE----------YDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQE 2011 Query: 69 LDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAA 128 L+ T + N + EAEL E Q+ET + ++ + E+ K A R Sbjct: 2012 LEMTIKETINKAQEVEAEL---LESHQEETNQL-------LKKIAEKDDDLKRTAKRYEE 2061 Query: 129 LVEAEKECNLELSEKLKGVTKNWEDV 154 +++A +E E++ K++ + E++ Sbjct: 2062 ILDAREE---EMTAKVRDLQTQLEEL 2084 Score = 36.6 bits (83), Expect = 0.011 Identities = 47/218 (21%), Positives = 93/218 (42%), Gaps = 56/218 (25%) Query: 7 TLSQHLNDLKKENFSLKLRIYFLEE---RMQQKYEASRED-------------------I 44 +LS L+++ K L+ + L++ +M+Q+ EA ++ I Sbjct: 688 SLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSI 747 Query: 45 YKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNS---QNEAELRRQ------FEERQ 95 + LK ++ L+ L+++ +HL + A VENL + ++E EL++ F+ Q Sbjct: 748 QRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQ 807 Query: 96 QETEHVYELLENKIQLLQEESRLAKNE---AARMAALVEAEKE--C-------------- 136 T + E ++ LQ++ + E + A VEA+K+ C Sbjct: 808 SATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLM 867 Query: 137 ------NLELSEKLKGVTKNWEDVPGDQVKPDQYTEAL 168 N E+ +K+K +T+ +E D K + T+ + Sbjct: 868 QQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQI 905 Score = 34.3 bits (77), Expect = 0.055 Identities = 38/165 (23%), Positives = 78/165 (47%), Gaps = 18/165 (10%) Query: 18 ENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVE 77 E+ L ++ +E ++K +E ++ + L+ +V S+K EL+ KK+ L+ V+ Sbjct: 1558 EHKELVQKLQHFQELGEEKDNRVKE-AEEKILTLENQVYSMKAELETKKKELEHVNLSVK 1616 Query: 78 N-------LNSQNEAELRRQFEERQQETEHVYELLENKI--QLLQEESRLAKNEAARMA- 127 + L + E+E + E +++ E ++ ++ Q+ ++E + K + ++ Sbjct: 1617 SKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSE 1676 Query: 128 ---ALVEAEKECNLELSEKLKGVTKNWED---VPGDQVKPDQYTE 166 L E E+E ++ L EKLK V + + VP YTE Sbjct: 1677 LNTKLQEREREVHI-LEEKLKSVESSQSETLIVPRSAKNVAAYTE 1720 Score = 32.7 bits (73), Expect = 0.16 Identities = 31/145 (21%), Positives = 63/145 (43%), Gaps = 15/145 (10%) Query: 8 LSQHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQ 67 L Q L DL+ E L ++ + EA ++D+ E+++ K ++QD Q Sbjct: 824 LQQKLLDLETERILLTKQV--------AEVEAQKKDVC-------TELDAHKIQVQDLMQ 868 Query: 68 HLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMA 127 L+K +++E + E+ +E E ++L K ++ + K E + Sbjct: 869 QLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILT 928 Query: 128 ALVEAEKECNLELSEKLKGVTKNWE 152 + A+++ L+E+ + KN E Sbjct: 929 QKLSAKEDSIHILNEEYETKFKNQE 953 Score = 31.6 bits (70), Expect = 0.36 Identities = 23/103 (22%), Positives = 52/103 (50%), Gaps = 2/103 (1%) Query: 9 SQHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQH 68 S H+N L ++ LK + LE + + + + + ++ +ELK+ E KR++ + Sbjct: 1119 SAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTF-LQEQLVELKMLAEEDKRKVSELTSK 1177 Query: 69 LDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQL 111 L T + ++L S +E + + E++ E + + E L ++ + Sbjct: 1178 LKTTDEEFQSLKSSHE-KSNKSLEDKSLEFKKLSEELAIQLDI 1219 Score = 30.0 bits (66), Expect = 1.0 Identities = 38/170 (22%), Positives = 70/170 (41%), Gaps = 25/170 (14%) Query: 7 TLSQHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKV-EVESLKRELQDK 65 TL Q + ++EN + + + Q S ++ + ++ ++ E+E +K + Sbjct: 283 TLQQRVK--RQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAE 340 Query: 66 KQHLDKTWADVENLNSQNE-------AELRRQFEERQQETEHVYELLENKIQLLQ---EE 115 K L D +NL Q E AE +RQ E + E L ++I+ + EE Sbjct: 341 KTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEE 400 Query: 116 SRLAKNEAARMA------------ALVEAEKECNLELSEKLKGVTKNWED 153 R K ++ R A EA ++ E+ E++K + K E+ Sbjct: 401 LREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEE 450 >gi|156104908 myosin heavy chain 6 [Homo sapiens] Length = 1939 Score = 43.5 bits (101), Expect = 9e-05 Identities = 32/148 (21%), Positives = 72/148 (48%), Gaps = 8/148 (5%) Query: 1 MSNGYRTLSQHLNDLKKENFSLKLRIYFLEERMQQ------KYEASREDIYKRNIELKVE 54 + N Y +HL K+EN +L+ I L E++ + + E R+ + +EL+ Sbjct: 1486 LKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSA 1545 Query: 55 VESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQE 114 +E + L+ ++ + + + + ++ E +L + EE +Q + ++++ L Sbjct: 1546 LEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDA 1605 Query: 115 ESRLAKNEAARMAALVEAE-KECNLELS 141 E+R ++NE R+ +E + E ++LS Sbjct: 1606 ETR-SRNEVLRVKKKMEGDLNEMEIQLS 1632 Score = 37.0 bits (84), Expect = 0.009 Identities = 35/145 (24%), Positives = 69/145 (47%), Gaps = 10/145 (6%) Query: 12 LNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDK 71 L+D + N LK I +E R +A E EL+ VE +R + +Q L + Sbjct: 1659 LDDAVRANDDLKENIAIVERR-NNLLQAELE-------ELRAVVEQTERSRKLAEQELIE 1710 Query: 72 TWADVENLNSQNEAEL--RRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAAL 129 T V+ L+SQN + + +++ E + + E + + +E+++ A +AA MA Sbjct: 1711 TSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEE 1770 Query: 130 VEAEKECNLELSEKLKGVTKNWEDV 154 ++ E++ + L K + + +D+ Sbjct: 1771 LKKEQDTSAHLERMKKNMEQTIKDL 1795 Score = 36.2 bits (82), Expect = 0.015 Identities = 37/173 (21%), Positives = 87/173 (50%), Gaps = 29/173 (16%) Query: 12 LNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDK 71 +N L K L+ ++ LE ++Q+ + +++++E KR+L+ + + Sbjct: 1019 VNSLSKSKVKLEQQVDDLEGSLEQEKK------------VRMDLERAKRKLEGDLKLTQE 1066 Query: 72 TWADVENLNSQNEAEL-RRQFEERQQETEHVYELLENKIQLLQEESRLAKNEA--ARMAA 128 + D+EN Q E +L +++F+ QQ + ++ + ++ LQ + +L +N+A + Sbjct: 1067 SIMDLENDKLQLEEKLKKKEFDINQQNS----KIEDEQVLALQLQKKLKENQARIEELEE 1122 Query: 129 LVEAEK-------ECNLELSEKLKGVTKNWEDVPGD---QVKPDQYTEALAQR 171 +EAE+ + +LS +L+ +++ E+ G Q++ ++ EA Q+ Sbjct: 1123 ELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQK 1175 Score = 33.1 bits (74), Expect = 0.12 Identities = 37/149 (24%), Positives = 67/149 (44%), Gaps = 25/149 (16%) Query: 14 DLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTW 73 + +KE ++K ++E ++ K EA R+++ ++ + L E L+ ++Q Sbjct: 846 ETEKEMATMKEEFGRIKETLE-KSEARRKELEEKMVSLLQEKNDLQLQVQ---------- 894 Query: 74 ADVENLNS-------------QNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAK 120 A+ +NLN Q EA+++ E + E E EL K +L E S L K Sbjct: 895 AEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKK 954 Query: 121 NEAARMAALVEAEKECNLELSEKLKGVTK 149 + L + EKE + K+K +T+ Sbjct: 955 DIDDLELTLAKVEKEKH-ATENKVKNLTE 982 Score = 31.6 bits (70), Expect = 0.36 Identities = 35/122 (28%), Positives = 55/122 (45%), Gaps = 16/122 (13%) Query: 31 ERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQ 90 ERM++ E + +D+ R E + + L+ K+ L K A V L + EAE +R Sbjct: 1782 ERMKKNMEQTIKDLQHRLDEAE------QIALKGGKKQLQKLEARVRELEGELEAEQKRN 1835 Query: 91 FEE----RQQET---EHVYELLENKIQLLQEE---SRLAKNEAARMAALVEAEKECNLEL 140 E R+ E E Y+ E+K LL+ + +L A EAE++ N L Sbjct: 1836 AESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNL 1895 Query: 141 SE 142 S+ Sbjct: 1896 SK 1897 Score = 31.2 bits (69), Expect = 0.47 Identities = 30/130 (23%), Positives = 61/130 (46%), Gaps = 10/130 (7%) Query: 30 EERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEA--EL 87 ++++ Q+ + + E + N + +E K LQ++ + L DVE N+ A + Sbjct: 1392 KKKLAQRLQDAEEAVEAVNAKCS-SLEKTKHRLQNEIEDL---MVDVERSNAAAAALDKK 1447 Query: 88 RRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGV 147 +R F++ E + YE +++++ Q+E+R E ++ E +LE E K Sbjct: 1448 QRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEE----SLEHLETFKRE 1503 Query: 148 TKNWEDVPGD 157 KN ++ D Sbjct: 1504 NKNLQEEISD 1513 Score = 30.8 bits (68), Expect = 0.61 Identities = 36/148 (24%), Positives = 66/148 (44%), Gaps = 9/148 (6%) Query: 7 TLSQHLNDLKKENFSLKLRIYFLEERMQQ------KYEASREDIYKR---NIELKVEVES 57 +L Q NDL+ + + + + EER Q + EA +++ +R E+ E+ + Sbjct: 881 SLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTA 940 Query: 58 LKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESR 117 KR+L+D+ L K D+E ++ E E + + TE + L E +L +E+ Sbjct: 941 KKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKA 1000 Query: 118 LAKNEAARMAALVEAEKECNLELSEKLK 145 L + + L E + N K+K Sbjct: 1001 LQEAHQQALDDLQVEEDKVNSLSKSKVK 1028 Score = 30.0 bits (66), Expect = 1.0 Identities = 23/86 (26%), Positives = 39/86 (45%), Gaps = 6/86 (6%) Query: 74 ADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAE 133 A+ E + + E R E ++ EL E + LLQE++ L A L +AE Sbjct: 845 AETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAE 904 Query: 134 KECN------LELSEKLKGVTKNWED 153 + C+ ++L K+K + + ED Sbjct: 905 ERCDQLIKNKIQLEAKVKEMNERLED 930 Score = 29.3 bits (64), Expect = 1.8 Identities = 20/124 (16%), Positives = 55/124 (44%) Query: 29 LEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELR 88 + ++ + +++ R D+ + ++ + +L+++ D L + +++ + + E E Sbjct: 1165 MNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKS 1224 Query: 89 RQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVT 148 E T ++ ++++ K L + L L EA++ N +++ K T Sbjct: 1225 EFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQT 1284 Query: 149 KNWE 152 +N E Sbjct: 1285 ENGE 1288 >gi|119120861 formin-like 3 isoform 2 [Homo sapiens] Length = 976 Score = 43.1 bits (100), Expect = 1e-04 Identities = 31/99 (31%), Positives = 47/99 (47%), Gaps = 13/99 (13%) Query: 42 EDIYKRNIEL-KVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEH 100 ED +N+ L KVE EL++ HL + D+EN N AEL +Q +R++E E Sbjct: 335 EDAETKNVALEKVE------ELEEHVSHLTEKLLDLENENMMRVAELEKQLLQREKELES 388 Query: 101 VYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLE 139 + E EN + RL K + ++ C+LE Sbjct: 389 IKETYENTSHQVHTLRRLIKEKEEAF------QRRCHLE 421 >gi|119120874 formin-like 3 isoform 1 [Homo sapiens] Length = 1027 Score = 43.1 bits (100), Expect = 1e-04 Identities = 31/99 (31%), Positives = 47/99 (47%), Gaps = 13/99 (13%) Query: 42 EDIYKRNIEL-KVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEH 100 ED +N+ L KVE EL++ HL + D+EN N AEL +Q +R++E E Sbjct: 386 EDAETKNVALEKVE------ELEEHVSHLTEKLLDLENENMMRVAELEKQLLQREKELES 439 Query: 101 VYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLE 139 + E EN + RL K + ++ C+LE Sbjct: 440 IKETYENTSHQVHTLRRLIKEKEEAF------QRRCHLE 472 >gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo sapiens] Length = 956 Score = 43.1 bits (100), Expect = 1e-04 Identities = 30/102 (29%), Positives = 53/102 (51%), Gaps = 2/102 (1%) Query: 23 KLRIYFLEERM--QQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLN 80 KLR+ +ER+ Q K A RE+ K E K E K++ +++K+ +K + + Sbjct: 334 KLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKD 393 Query: 81 SQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNE 122 + +AE +R EER++E + E + + +EE RL + E Sbjct: 394 EKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEE 435 >gi|50658071 phosphodiesterase 4D interacting protein isoform 5 [Homo sapiens] Length = 1132 Score = 42.7 bits (99), Expect = 2e-04 Identities = 35/115 (30%), Positives = 52/115 (45%), Gaps = 16/115 (13%) Query: 31 ERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQ 90 E + E +E +K N EL+ ++ L+ ELQ+K Q L + W EAE + Sbjct: 543 EAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQL-RAW----------EAEKYNE 591 Query: 91 FEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLK 145 ++Q +H+ L +K QLLQE L + L E N L EKL+ Sbjct: 592 IRTQEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTL-----EANEMLLEKLR 641 >gi|16262452 cingulin [Homo sapiens] Length = 1203 Score = 42.7 bits (99), Expect = 2e-04 Identities = 34/138 (24%), Positives = 69/138 (50%), Gaps = 18/138 (13%) Query: 2 SNGYRTLSQHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRE 61 S G++ S L+ L+ +N L+ R+ EER + +++ + ++ EL +++E ++ Sbjct: 1037 SEGFQKPSASLSQLESQNQLLQERLQ-AEEREKTVLQSTNRKLERKVKELSIQIEDERQH 1095 Query: 62 LQDKKQHL-----------DKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQ 110 + D+K L D+ ++E L+ LR++ + +E V E L+ +I+ Sbjct: 1096 VNDQKDQLSLRVKALKRQVDEAEEEIERLDG-----LRKKAQREVEEQHEVNEQLQARIK 1150 Query: 111 LLQEES-RLAKNEAARMA 127 L+++S R A AA A Sbjct: 1151 SLEKDSWRKASRSAAESA 1168 Score = 34.3 bits (77), Expect = 0.055 Identities = 36/150 (24%), Positives = 66/150 (44%), Gaps = 12/150 (8%) Query: 6 RTLSQHLNDLKKENFSLKLRIYFLEERMQQKYEASR---EDIYKRNIELKVE-------V 55 R L+ LK+E S + + ++ Q+ E R +D + + L+ E V Sbjct: 495 RELTALKGALKEEVASRDQEVEHVRQQYQRDTEQLRRSMQDATQDHAVLEAERQKMSALV 554 Query: 56 ESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEE 115 L+REL++ + W + N ++ +++ + + E E + E L KI++LQ E Sbjct: 555 RGLQRELEETSEETGH-WQSMFQKNKEDLRATKQELLQLRMEKEEMEEELGEKIEVLQRE 613 Query: 116 SRLAKNEAARMAALVEAEKECNLELSEKLK 145 A+ A + +KE L E+LK Sbjct: 614 LEQARASAGDTRQVEVLKKEL-LRTQEELK 642 Score = 33.9 bits (76), Expect = 0.072 Identities = 28/105 (26%), Positives = 49/105 (46%), Gaps = 19/105 (18%) Query: 50 ELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKI 109 EL +VE L+R+L ++ + K ++ L RQ EE+ +E + ELLE + Sbjct: 363 ELTRKVEELQRKLDEEVKKRQKL--------EPSQVGLERQLEEKTEECSRLQELLERR- 413 Query: 110 QLLQEESRLAKNEAARMAALVEAEKECN-------LELSEKLKGV 147 + E++ + E M L++ ++ +EL KLK V Sbjct: 414 ---KGEAQQSNKELQNMKRLLDQGEDLRHGLETQVMELQNKLKHV 455 >gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens] Length = 1219 Score = 42.7 bits (99), Expect = 2e-04 Identities = 42/147 (28%), Positives = 75/147 (51%), Gaps = 21/147 (14%) Query: 31 ERMQQKYEASREDIYKRNIELKVEVESLKRELQD---KKQHLDKTWADVENLNSQNEAEL 87 E+ Q K+++ +++ ++ +ELKV SL+ EL D +K+ L+K ++ + A+ Sbjct: 702 EQAQSKFKSEKQN--RKQLELKVT--SLEEELTDLRVEKESLEKNLSE----RKKKSAQE 753 Query: 88 RRQFEERQQETEHVYELLENKIQLLQEESRLAKNE-AARMAALVEAEKECNLELS-EKLK 145 R Q EE E Y+ +K++ L +++R++ ++ AA +LV+AE + E E L Sbjct: 754 RSQAEEEIDEIRKSYQEELDKLRQLLKKTRVSTDQAAAEQLSLVQAELQTQWEAKCEHLL 813 Query: 146 GVTKNWEDVPGDQVKPDQYTEALAQRD 172 K+ QY E AQRD Sbjct: 814 ASAKD--------EHLQQYQEVCAQRD 832 Score = 39.7 bits (91), Expect = 0.001 Identities = 39/146 (26%), Positives = 72/146 (49%), Gaps = 9/146 (6%) Query: 7 TLSQHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKK 66 +L + L DL+ E SL+ + +++ Q+ + E+I + + E++ L++ L KK Sbjct: 724 SLEEELTDLRVEKESLEKNLSERKKKSAQERSQAEEEIDEIRKSYQEELDKLRQLL--KK 781 Query: 67 QHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARM 126 + A E L S +AEL+ Q+E + EH+ L K + LQ+ + A Sbjct: 782 TRVSTDQAAAEQL-SLVQAELQTQWEAK---CEHL--LASAKDEHLQQYQEVCAQRDAYQ 835 Query: 127 AALVEAEKECNLELSEKLKGVTKNWE 152 LV+ +++C L L ++ +TK E Sbjct: 836 QKLVQLQEKC-LALQAQITALTKQNE 860 >gi|239745153 PREDICTED: similar to Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 655 Score = 42.4 bits (98), Expect = 2e-04 Identities = 29/128 (22%), Positives = 61/128 (47%), Gaps = 5/128 (3%) Query: 30 EERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNS-----QNE 84 EE M ++ E RE KR ++ + + ++ + + ++ ++ W E + Q++ Sbjct: 387 EEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQ 446 Query: 85 AELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKL 144 E R+ EE+ QE E + E KIQ +E+ + + + R L++ E++ + + Sbjct: 447 EEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMW 506 Query: 145 KGVTKNWE 152 + K WE Sbjct: 507 RQEEKMWE 514 Score = 36.6 bits (83), Expect = 0.011 Identities = 33/163 (20%), Positives = 77/163 (47%), Gaps = 15/163 (9%) Query: 23 KLRIYFLEERM---QQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENL 79 +L+I EE+M ++K E I ++ ++ + E ++ + + ++ +K W E + Sbjct: 317 ELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKI 376 Query: 80 NSQN------EAELRRQFEERQQETEHVYELL---ENKIQLLQEESRLAKNEAARMAALV 130 Q+ E E+ RQ E+ +++ E E + E K++ E+ R + E R + Sbjct: 377 REQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKI 436 Query: 131 EAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTEALAQRDK 173 +E + EKL+ V + ++ ++ K + E + ++++ Sbjct: 437 RELEEMMQDQEEKLREVEEKMQE---EEEKMQEQEEKIQRQEE 476 Score = 35.8 bits (81), Expect = 0.019 Identities = 23/93 (24%), Positives = 48/93 (51%), Gaps = 4/93 (4%) Query: 31 ERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQ 90 +R ++K + E +++ LK E + ++E + +Q +K W E + Q E R++ Sbjct: 472 QRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQE-EKMWEQEEKMQEQEEKMQRQE 530 Query: 91 FEERQQET---EHVYELLENKIQLLQEESRLAK 120 + R+QE + ++ E +++L + E RL K Sbjct: 531 EKMREQEVRLWQQEEKMQEQEVRLQELEERLGK 563 Score = 33.9 bits (76), Expect = 0.072 Identities = 32/157 (20%), Positives = 65/157 (41%), Gaps = 28/157 (17%) Query: 14 DLKKENFSLKLRIYFLEERMQQ--------KYEASREDIYKRNIELKVEVESLKRELQD- 64 +LK++N L+ ++ +E + K + R + +L+VE + L +ELQ Sbjct: 215 ELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSV 274 Query: 65 -----------------KKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLEN 107 +Q +K W E + Q E ++ + R+QE + + E Sbjct: 275 SAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQ--EE 332 Query: 108 KIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKL 144 K+ +E+ R +++ R + ++E E EK+ Sbjct: 333 KMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKM 369 >gi|239745127 PREDICTED: similar to Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 655 Score = 42.4 bits (98), Expect = 2e-04 Identities = 29/128 (22%), Positives = 61/128 (47%), Gaps = 5/128 (3%) Query: 30 EERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNS-----QNE 84 EE M ++ E RE KR ++ + + ++ + + ++ ++ W E + Q++ Sbjct: 387 EEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQ 446 Query: 85 AELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKL 144 E R+ EE+ QE E + E KIQ +E+ + + + R L++ E++ + + Sbjct: 447 EEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMW 506 Query: 145 KGVTKNWE 152 + K WE Sbjct: 507 RQEEKMWE 514 Score = 36.6 bits (83), Expect = 0.011 Identities = 33/163 (20%), Positives = 77/163 (47%), Gaps = 15/163 (9%) Query: 23 KLRIYFLEERM---QQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENL 79 +L+I EE+M ++K E I ++ ++ + E ++ + + ++ +K W E + Sbjct: 317 ELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKI 376 Query: 80 NSQN------EAELRRQFEERQQETEHVYELL---ENKIQLLQEESRLAKNEAARMAALV 130 Q+ E E+ RQ E+ +++ E E + E K++ E+ R + E R + Sbjct: 377 REQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKI 436 Query: 131 EAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTEALAQRDK 173 +E + EKL+ V + ++ ++ K + E + ++++ Sbjct: 437 RELEEMMQDQEEKLREVEEKMQE---EEEKMQEQEEKIQRQEE 476 Score = 35.8 bits (81), Expect = 0.019 Identities = 23/93 (24%), Positives = 48/93 (51%), Gaps = 4/93 (4%) Query: 31 ERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQ 90 +R ++K + E +++ LK E + ++E + +Q +K W E + Q E R++ Sbjct: 472 QRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQE-EKMWEQEEKMQEQEEKMQRQE 530 Query: 91 FEERQQET---EHVYELLENKIQLLQEESRLAK 120 + R+QE + ++ E +++L + E RL K Sbjct: 531 EKMREQEVRLWQQEEKMQEQEVRLQELEERLGK 563 Score = 33.9 bits (76), Expect = 0.072 Identities = 32/157 (20%), Positives = 65/157 (41%), Gaps = 28/157 (17%) Query: 14 DLKKENFSLKLRIYFLEERMQQ--------KYEASREDIYKRNIELKVEVESLKRELQD- 64 +LK++N L+ ++ +E + K + R + +L+VE + L +ELQ Sbjct: 215 ELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSV 274 Query: 65 -----------------KKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLEN 107 +Q +K W E + Q E ++ + R+QE + + E Sbjct: 275 SAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQ--EE 332 Query: 108 KIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKL 144 K+ +E+ R +++ R + ++E E EK+ Sbjct: 333 KMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKM 369 >gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo sapiens] Length = 1002 Score = 42.4 bits (98), Expect = 2e-04 Identities = 43/170 (25%), Positives = 82/170 (48%), Gaps = 33/170 (19%) Query: 1 MSNGYRTLSQHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKR 60 +S + ++ +L KE +L+L +Y K S ED+ + EL+ ++ L Sbjct: 275 VSTQQKKADRYNKELTKERDALRLELY--------KNTQSNEDLKQEKSELEEKLRVLVT 326 Query: 61 E-------LQDKKQHLDKTWADVENLNSQNEA-----ELRRQFEERQQETEHVYELLENK 108 E L++ ++ L+ T ++ +S+ EA +L++ EER Q H+ +++E+ Sbjct: 327 EKAGMQLNLEELQKKLEMTELLLQQFSSRCEAPDANQQLQQAMEERAQLEAHLGQVMESV 386 Query: 109 IQLLQEESRLAKN---EAA----RMAALVE------AEKECNLELSEKLK 145 QL E + A+N E+A RM + E EKEC++ ++L+ Sbjct: 387 RQLQMERDKYAENLKGESAMWRQRMQQMSEQVHTLREEKECSMSRVQELE 436 >gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] Length = 1976 Score = 42.4 bits (98), Expect = 2e-04 Identities = 40/135 (29%), Positives = 63/135 (46%), Gaps = 7/135 (5%) Query: 11 HLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLD 70 H N+ K L+ +I L+E + + +ASR K+ +L E+E+LK EL+D LD Sbjct: 1105 HKNNALKVVRELQAQIAELQEDFESE-KASRNKAEKQKRDLSEELEALKTELEDT---LD 1160 Query: 71 KTWA--DVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAA 128 T A ++ Q AEL++ EE + E + + + EE +A R A Sbjct: 1161 TTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKA 1220 Query: 129 LVEAEKECNLELSEK 143 +E K+ LE K Sbjct: 1221 NLEKNKQ-GLETDNK 1234 Score = 39.3 bits (90), Expect = 0.002 Identities = 27/110 (24%), Positives = 59/110 (53%), Gaps = 7/110 (6%) Query: 32 RMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHL-DKTWADVENLNSQNEA----- 85 R +++ +A E++ K E + +VE E++ K Q L ++ E L ++ E Sbjct: 849 RQEEELQAKDEELLKVK-EKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAE 907 Query: 86 ELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKE 135 E+R + ++QE E + LE++++ +E +++ +NE +M A ++ +E Sbjct: 908 EMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEE 957 Score = 39.3 bits (90), Expect = 0.002 Identities = 30/138 (21%), Positives = 65/138 (47%), Gaps = 7/138 (5%) Query: 23 KLRIYFLEERMQQKYEASR-----EDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVE 77 +LR+ E+ + + E E+ K+ I+ + SL+ +LQD ++ L + Sbjct: 1273 RLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKL 1332 Query: 78 NLNS--QNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKE 135 NL+S + E + +E+Q+E E + LE ++ LQ + K + +E+ +E Sbjct: 1333 NLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEE 1392 Query: 136 CNLELSEKLKGVTKNWED 153 +L + + +++ E+ Sbjct: 1393 AKKKLLKDAEALSQRLEE 1410 Score = 35.8 bits (81), Expect = 0.019 Identities = 26/132 (19%), Positives = 67/132 (50%), Gaps = 2/132 (1%) Query: 15 LKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWA 74 L+++N LK ++ LE ++ K++A+ + + +L+ ++E +E + + +T Sbjct: 1790 LERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEK 1849 Query: 75 DVENLNSQNEAELRR--QFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEA 132 ++ + Q E E R Q++E+ ++ + L+ +++ +EE+ A ++ ++ Sbjct: 1850 KLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDD 1909 Query: 133 EKECNLELSEKL 144 E N LS ++ Sbjct: 1910 ATEANEGLSREV 1921 Score = 35.0 bits (79), Expect = 0.032 Identities = 29/127 (22%), Positives = 59/127 (46%), Gaps = 5/127 (3%) Query: 10 QHLNDLKKENFSLKLRIYFLEERMQQKYEASR--EDIYKRNIELKVEVESLKRELQDKKQ 67 + L +K++ ++ + +E + QQ E + + EL E E ++ L KKQ Sbjct: 859 EELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQ 918 Query: 68 HLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMA 127 L++ D+E+ + E + E+++ H+ +L E QL +EE K + ++ Sbjct: 919 ELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEE---QLDEEEGARQKLQLEKVT 975 Query: 128 ALVEAEK 134 A + +K Sbjct: 976 AEAKIKK 982 Score = 33.9 bits (76), Expect = 0.072 Identities = 34/148 (22%), Positives = 66/148 (44%), Gaps = 11/148 (7%) Query: 8 LSQHLNDLKKENFSLKLRIYFLEERMQQKY-EASREDIYKRNI-----ELKVEVESLKRE 61 L + +L+ + LKL++ EE +Q E ++K N EL+ ++ L+ + Sbjct: 1067 LQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQED 1126 Query: 62 LQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRL--- 118 + +K +K +L+ + EA L+ + E+ T EL + Q + E + Sbjct: 1127 FESEKASRNKAEKQKRDLSEELEA-LKTELEDTLDTTAAQQELRTKREQEVAELKKALEE 1185 Query: 119 -AKNEAARMAALVEAEKECNLELSEKLK 145 KN A++ + + ELSE+L+ Sbjct: 1186 ETKNHEAQIQDMRQRHATALEELSEQLE 1213 Score = 32.7 bits (73), Expect = 0.16 Identities = 30/119 (25%), Positives = 56/119 (47%), Gaps = 8/119 (6%) Query: 42 EDIYKRNIELKVEVESLKRELQ----DKKQHLDKTWADVENLNSQ---NEAELRRQFEER 94 E+ K+ + + E+E KR+L D + + + A ++ L Q E EL+ Sbjct: 1040 EERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARG 1099 Query: 95 QQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWED 153 ET H L+ +L + + L ++ + A+ +AEK+ +LSE+L+ + ED Sbjct: 1100 DDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQ-KRDLSEELEALKTELED 1157 Score = 28.9 bits (63), Expect = 2.3 Identities = 31/149 (20%), Positives = 64/149 (42%), Gaps = 3/149 (2%) Query: 8 LSQHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQ 67 L L D KK+ I LEE ++K E + +R E + + L++ +Q Sbjct: 1369 LQSQLADTKKKVDDDLGTIESLEEA-KKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQ 1427 Query: 68 HLDKTWADVENLN--SQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAAR 125 LD D+++ + N + +++F++ E + + + + E+R + +A Sbjct: 1428 ELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALS 1487 Query: 126 MAALVEAEKECNLELSEKLKGVTKNWEDV 154 +A +E E E + K + + ED+ Sbjct: 1488 LARALEEALEAKEEFERQNKQLRADMEDL 1516 Score = 28.1 bits (61), Expect = 4.0 Identities = 21/104 (20%), Positives = 52/104 (50%), Gaps = 3/104 (2%) Query: 31 ERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQ 90 E + +EA +D+ +R+ E+ + + K +L+K +E N + E+ + Sbjct: 1184 EEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEV-KV 1242 Query: 91 FEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEK 134 ++ + E+EH + L+ ++Q L +++++ + R+ +A K Sbjct: 1243 LQQVKAESEHKRKKLDAQVQEL--HAKVSEGDRLRVELAEKASK 1284 >gi|29171755 PTPRF interacting protein alpha 2 [Homo sapiens] Length = 1257 Score = 42.4 bits (98), Expect = 2e-04 Identities = 35/147 (23%), Positives = 72/147 (48%), Gaps = 13/147 (8%) Query: 15 LKKENFSL---KLRIYFLEERM---QQKYEASREDIYKRNIELKVEVESLKRELQDKKQH 68 L+K+N+ + K R+ L R+ +Q+ E +R+D+ K E+ + + RE +K+ Sbjct: 277 LEKQNYEMAQMKERLAALSSRVGEVEQEAETARKDLIKTE-EMNTKYQRDIREAMAQKED 335 Query: 69 LDKTWADVEN--LNSQNEA----ELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNE 122 +++ +E L++Q E+ ++ + E E + +E K + LQE LA+ + Sbjct: 336 MEERITTLEKRYLSAQRESTSIHDMNDKLENELANKEAILRQMEEKNRQLQERLELAEQK 395 Query: 123 AARMAALVEAEKECNLELSEKLKGVTK 149 + E E EL++++ +TK Sbjct: 396 LQQTMRKAETLPEVEAELAQRIAALTK 422 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.309 0.126 0.337 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 5,804,176 Number of Sequences: 37866 Number of extensions: 235952 Number of successful extensions: 4083 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 288 Number of HSP's successfully gapped in prelim test: 666 Number of HSP's that attempted gapping in prelim test: 2139 Number of HSP's gapped (non-prelim): 2241 length of query: 173 length of database: 18,247,518 effective HSP length: 95 effective length of query: 78 effective length of database: 14,650,248 effective search space: 1142719344 effective search space used: 1142719344 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.