Guide to the Human Genome
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Search of human proteins with 5032201

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5032201 transmembrane 4 superfamily member 8 isoform 1 [Homo
sapiens]
         (253 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5032201 transmembrane 4 superfamily member 8 isoform 1 [Homo ...   519   e-147
gi|38787991 transmembrane 4 superfamily member 8 isoform 2 [Homo...   460   e-130
gi|21265104 tetraspanin 7 [Homo sapiens]                              130   8e-31
gi|87159824 CD151 antigen [Homo sapiens]                              129   2e-30
gi|87159822 CD151 antigen [Homo sapiens]                              129   2e-30
gi|21237751 CD151 antigen [Homo sapiens]                              129   2e-30
gi|21237748 CD151 antigen [Homo sapiens]                              129   2e-30
gi|4507541 transmembrane 4 superfamily member 6 [Homo sapiens]        128   4e-30
gi|68800005 tetraspanin 4 isoform a [Homo sapiens]                    117   1e-26
gi|4507543 tetraspanin 4 isoform a [Homo sapiens]                     117   1e-26
gi|68800018 tetraspanin 4 isoform a [Homo sapiens]                    117   1e-26
gi|68800024 tetraspanin 4 isoform a [Homo sapiens]                    117   1e-26
gi|68800011 tetraspanin 4 isoform a [Homo sapiens]                    117   1e-26
gi|68799997 tetraspanin 4 isoform a [Homo sapiens]                    117   1e-26
gi|4502679 CD63 antigen isoform A [Homo sapiens]                      114   6e-26
gi|5729941 tetraspanin 9 [Homo sapiens]                               110   2e-24
gi|91199546 CD63 antigen isoform B [Homo sapiens]                     108   4e-24
gi|4504813 CD82 antigen isoform 1 [Homo sapiens]                      105   4e-23
gi|122937466 tetraspanin 11 [Homo sapiens]                            103   2e-22
gi|10834972 CD53 antigen [Homo sapiens]                               103   2e-22
gi|91106727 CD53 antigen [Homo sapiens]                               103   2e-22
gi|21264578 tetraspan 1 [Homo sapiens]                                100   9e-22
gi|68800032 tetraspanin 4 isoform b [Homo sapiens]                     98   8e-21
gi|4759238 transmembrane 4 superfamily member 3 [Homo sapiens]         95   7e-20
gi|30425534 tetraspanin 33 [Homo sapiens]                              94   9e-20
gi|42476204 tetraspanin 18 isoform 2 [Homo sapiens]                    92   3e-19
gi|72534746 tetraspanin 18 isoform 1 [Homo sapiens]                    88   8e-18
gi|4502663 CD37 antigen isoform A [Homo sapiens]                       87   1e-17
gi|91807110 CD37 antigen isoform B [Homo sapiens]                      82   4e-16
gi|67782354 CD82 antigen isoform 2 [Homo sapiens]                      80   2e-15

>gi|5032201 transmembrane 4 superfamily member 8 isoform 1 [Homo
           sapiens]
          Length = 253

 Score =  519 bits (1336), Expect = e-147
 Identities = 253/253 (100%), Positives = 253/253 (100%)

Query: 1   MGQCGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAV 60
           MGQCGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAV
Sbjct: 1   MGQCGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAV 60

Query: 61  GALLFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQ 120
           GALLFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQ
Sbjct: 61  GALLFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQ 120

Query: 121 KVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETAS 180
           KVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETAS
Sbjct: 121 KVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETAS 180

Query: 181 NCNGSLAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSRD 240
           NCNGSLAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSRD
Sbjct: 181 NCNGSLAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSRD 240

Query: 241 PAYELLITGGTYA 253
           PAYELLITGGTYA
Sbjct: 241 PAYELLITGGTYA 253


>gi|38787991 transmembrane 4 superfamily member 8 isoform 2 [Homo
           sapiens]
          Length = 228

 Score =  460 bits (1184), Expect = e-130
 Identities = 228/253 (90%), Positives = 228/253 (90%), Gaps = 25/253 (9%)

Query: 1   MGQCGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAV 60
           MGQCGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAV
Sbjct: 1   MGQCGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAV 60

Query: 61  GALLFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQ 120
           GALLFIIGLIGCCATIRESRCGLAT                         VENEVDRSIQ
Sbjct: 61  GALLFIIGLIGCCATIRESRCGLAT-------------------------VENEVDRSIQ 95

Query: 121 KVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETAS 180
           KVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETAS
Sbjct: 96  KVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETAS 155

Query: 181 NCNGSLAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSRD 240
           NCNGSLAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSRD
Sbjct: 156 NCNGSLAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSRD 215

Query: 241 PAYELLITGGTYA 253
           PAYELLITGGTYA
Sbjct: 216 PAYELLITGGTYA 228


>gi|21265104 tetraspanin 7 [Homo sapiens]
          Length = 249

 Score =  130 bits (328), Expect = 8e-31
 Identities = 80/231 (34%), Positives = 119/231 (51%), Gaps = 12/231 (5%)

Query: 6   ITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAVGALLF 65
           IT  KT+L+  + +FW    IL  VG +  +T   Y     +  T  P  V+I  G  + 
Sbjct: 12  ITCLKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAENSTNAP-YVLIGTGTTIV 70

Query: 66  IIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQKVYKT 125
           + GL GC AT R S   L  + + L LVF+ E+V  + G+V+R ++++   R+     +T
Sbjct: 71  VFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAMQT 130

Query: 126 YNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETASNCNGS 185
           YNG   D  SRA+D+VQR L CCG+ NY++W  + +F E     +P SCC    ++CN  
Sbjct: 131 YNGN--DERSRAVDHVQRSLSCCGVQNYTNWSTSPYFLE---HGIPPSCCM-NETDCNPQ 184

Query: 186 LAHPSDLYA-----EGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCAC 231
             H   + A     +GC  LV   ++  M  +   A   A  QL+GML AC
Sbjct: 185 DLHNLTVAATKVNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIGMLLAC 235


>gi|87159824 CD151 antigen [Homo sapiens]
          Length = 253

 Score =  129 bits (325), Expect = 2e-30
 Identities = 67/233 (28%), Positives = 119/233 (51%), Gaps = 6/233 (2%)

Query: 4   CGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAVGAL 63
           CG    K +L   N  FW A   +  VG +      DY         L  A +++  G +
Sbjct: 11  CGTVCLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTYLATAYILVVAGTV 70

Query: 64  LFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQ-KV 122
           + + G++GCCAT +E R  L  + I+LL++F+ E++  +L Y Y  ++  E+  +++  +
Sbjct: 71  VMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENLKDTM 130

Query: 123 YKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFK--ETKNQSVPLSCCRETAS 180
            K Y+    +A + A+D +Q++ HCCG +N  DW +++W +  E   + VP SCC+   +
Sbjct: 131 TKRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVVPDSCCKTVVA 190

Query: 181 NCNGSLAHPSDLY--AEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCAC 231
            C G   H S++Y    GC   +   +QE +  +    +  A +Q+ GM+  C
Sbjct: 191 LC-GQRDHASNIYKVEGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFTC 242


>gi|87159822 CD151 antigen [Homo sapiens]
          Length = 253

 Score =  129 bits (325), Expect = 2e-30
 Identities = 67/233 (28%), Positives = 119/233 (51%), Gaps = 6/233 (2%)

Query: 4   CGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAVGAL 63
           CG    K +L   N  FW A   +  VG +      DY         L  A +++  G +
Sbjct: 11  CGTVCLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTYLATAYILVVAGTV 70

Query: 64  LFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQ-KV 122
           + + G++GCCAT +E R  L  + I+LL++F+ E++  +L Y Y  ++  E+  +++  +
Sbjct: 71  VMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENLKDTM 130

Query: 123 YKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFK--ETKNQSVPLSCCRETAS 180
            K Y+    +A + A+D +Q++ HCCG +N  DW +++W +  E   + VP SCC+   +
Sbjct: 131 TKRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVVPDSCCKTVVA 190

Query: 181 NCNGSLAHPSDLY--AEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCAC 231
            C G   H S++Y    GC   +   +QE +  +    +  A +Q+ GM+  C
Sbjct: 191 LC-GQRDHASNIYKVEGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFTC 242


>gi|21237751 CD151 antigen [Homo sapiens]
          Length = 253

 Score =  129 bits (325), Expect = 2e-30
 Identities = 67/233 (28%), Positives = 119/233 (51%), Gaps = 6/233 (2%)

Query: 4   CGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAVGAL 63
           CG    K +L   N  FW A   +  VG +      DY         L  A +++  G +
Sbjct: 11  CGTVCLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTYLATAYILVVAGTV 70

Query: 64  LFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQ-KV 122
           + + G++GCCAT +E R  L  + I+LL++F+ E++  +L Y Y  ++  E+  +++  +
Sbjct: 71  VMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENLKDTM 130

Query: 123 YKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFK--ETKNQSVPLSCCRETAS 180
            K Y+    +A + A+D +Q++ HCCG +N  DW +++W +  E   + VP SCC+   +
Sbjct: 131 TKRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVVPDSCCKTVVA 190

Query: 181 NCNGSLAHPSDLY--AEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCAC 231
            C G   H S++Y    GC   +   +QE +  +    +  A +Q+ GM+  C
Sbjct: 191 LC-GQRDHASNIYKVEGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFTC 242


>gi|21237748 CD151 antigen [Homo sapiens]
          Length = 253

 Score =  129 bits (325), Expect = 2e-30
 Identities = 67/233 (28%), Positives = 119/233 (51%), Gaps = 6/233 (2%)

Query: 4   CGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAVGAL 63
           CG    K +L   N  FW A   +  VG +      DY         L  A +++  G +
Sbjct: 11  CGTVCLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASGTYLATAYILVVAGTV 70

Query: 64  LFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQ-KV 122
           + + G++GCCAT +E R  L  + I+LL++F+ E++  +L Y Y  ++  E+  +++  +
Sbjct: 71  VMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELKENLKDTM 130

Query: 123 YKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFK--ETKNQSVPLSCCRETAS 180
            K Y+    +A + A+D +Q++ HCCG +N  DW +++W +  E   + VP SCC+   +
Sbjct: 131 TKRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVVPDSCCKTVVA 190

Query: 181 NCNGSLAHPSDLY--AEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCAC 231
            C G   H S++Y    GC   +   +QE +  +    +  A +Q+ GM+  C
Sbjct: 191 LC-GQRDHASNIYKVEGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFTC 242


>gi|4507541 transmembrane 4 superfamily member 6 [Homo sapiens]
          Length = 245

 Score =  128 bits (322), Expect = 4e-30
 Identities = 77/241 (31%), Positives = 125/241 (51%), Gaps = 9/241 (3%)

Query: 6   ITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAVGALLF 65
           IT  K+VL+    IFW    IL  VG +  ++ ++Y     +  T +P  V+IA G ++ 
Sbjct: 14  ITCFKSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLLNEKATNVP-FVLIATGTVII 72

Query: 66  IIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQKVYKT 125
           ++G  GC AT R S   L  + + L LVF+ E+V  ++G+V+R +++N    + +K  K 
Sbjct: 73  LLGTFGCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIKNSFKNNYEKALKQ 132

Query: 126 YNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETASNCNGS 185
           YN T  D  S A+D +Q  LHCCG+ +Y DW +T+++ E   +  P SCC+    +C   
Sbjct: 133 YNSTG-DYRSHAVDKIQNTLHCCGVTDYRDWTDTNYYSE---KGFPKSCCK--LEDCTPQ 186

Query: 186 LAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSRDPAYEL 245
                 +  EGC   V+  ++  M  V   +   A  QL+G+  A   L R   +  YE+
Sbjct: 187 -RDADKVNNEGCFIKVMTIIESEMGVVAGISFGVACFQLIGIFLA-YCLSRAITNNQYEI 244

Query: 246 L 246
           +
Sbjct: 245 V 245


>gi|68800005 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score =  117 bits (293), Expect = 1e-26
 Identities = 72/244 (29%), Positives = 116/244 (47%), Gaps = 9/244 (3%)

Query: 1   MGQCGITSSKTVLVFLNLIFW-GAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIA 59
           M +  + + K ++   NL+FW G  G+L  VG ++  T   +        +L  A ++I 
Sbjct: 1   MARACLQAVKYLMFAFNLLFWLGGCGVLG-VGIWLAATQGSFATLSSSFPSLSAANLLII 59

Query: 60  VGALLFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSI 119
            GA +  IG +GC   I+E++C L TF ++LLLVF+ E  + +L + Y  K++    + +
Sbjct: 60  TGAFVMAIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDL 119

Query: 120 QKVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETA 179
           +K    Y        + A   +Q    CCG+ NY     TDWF+      VP SCC E +
Sbjct: 120 KKGLHLYGTQGNVGLTNAWSIIQTDFRCCGVSNY-----TDWFEVYNATRVPDSCCLEFS 174

Query: 180 SNCNGSLAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSR 239
            +C   L  P   +   C   V   LQE ++ V    L  A +Q+LG+  A  + C+  +
Sbjct: 175 ESC--GLHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFAMTMYCQVVK 232

Query: 240 DPAY 243
              Y
Sbjct: 233 ADTY 236


>gi|4507543 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score =  117 bits (293), Expect = 1e-26
 Identities = 72/244 (29%), Positives = 116/244 (47%), Gaps = 9/244 (3%)

Query: 1   MGQCGITSSKTVLVFLNLIFW-GAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIA 59
           M +  + + K ++   NL+FW G  G+L  VG ++  T   +        +L  A ++I 
Sbjct: 1   MARACLQAVKYLMFAFNLLFWLGGCGVLG-VGIWLAATQGSFATLSSSFPSLSAANLLII 59

Query: 60  VGALLFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSI 119
            GA +  IG +GC   I+E++C L TF ++LLLVF+ E  + +L + Y  K++    + +
Sbjct: 60  TGAFVMAIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDL 119

Query: 120 QKVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETA 179
           +K    Y        + A   +Q    CCG+ NY     TDWF+      VP SCC E +
Sbjct: 120 KKGLHLYGTQGNVGLTNAWSIIQTDFRCCGVSNY-----TDWFEVYNATRVPDSCCLEFS 174

Query: 180 SNCNGSLAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSR 239
            +C   L  P   +   C   V   LQE ++ V    L  A +Q+LG+  A  + C+  +
Sbjct: 175 ESC--GLHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFAMTMYCQVVK 232

Query: 240 DPAY 243
              Y
Sbjct: 233 ADTY 236


>gi|68800018 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score =  117 bits (293), Expect = 1e-26
 Identities = 72/244 (29%), Positives = 116/244 (47%), Gaps = 9/244 (3%)

Query: 1   MGQCGITSSKTVLVFLNLIFW-GAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIA 59
           M +  + + K ++   NL+FW G  G+L  VG ++  T   +        +L  A ++I 
Sbjct: 1   MARACLQAVKYLMFAFNLLFWLGGCGVLG-VGIWLAATQGSFATLSSSFPSLSAANLLII 59

Query: 60  VGALLFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSI 119
            GA +  IG +GC   I+E++C L TF ++LLLVF+ E  + +L + Y  K++    + +
Sbjct: 60  TGAFVMAIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDL 119

Query: 120 QKVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETA 179
           +K    Y        + A   +Q    CCG+ NY     TDWF+      VP SCC E +
Sbjct: 120 KKGLHLYGTQGNVGLTNAWSIIQTDFRCCGVSNY-----TDWFEVYNATRVPDSCCLEFS 174

Query: 180 SNCNGSLAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSR 239
            +C   L  P   +   C   V   LQE ++ V    L  A +Q+LG+  A  + C+  +
Sbjct: 175 ESC--GLHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFAMTMYCQVVK 232

Query: 240 DPAY 243
              Y
Sbjct: 233 ADTY 236


>gi|68800024 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score =  117 bits (293), Expect = 1e-26
 Identities = 72/244 (29%), Positives = 116/244 (47%), Gaps = 9/244 (3%)

Query: 1   MGQCGITSSKTVLVFLNLIFW-GAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIA 59
           M +  + + K ++   NL+FW G  G+L  VG ++  T   +        +L  A ++I 
Sbjct: 1   MARACLQAVKYLMFAFNLLFWLGGCGVLG-VGIWLAATQGSFATLSSSFPSLSAANLLII 59

Query: 60  VGALLFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSI 119
            GA +  IG +GC   I+E++C L TF ++LLLVF+ E  + +L + Y  K++    + +
Sbjct: 60  TGAFVMAIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDL 119

Query: 120 QKVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETA 179
           +K    Y        + A   +Q    CCG+ NY     TDWF+      VP SCC E +
Sbjct: 120 KKGLHLYGTQGNVGLTNAWSIIQTDFRCCGVSNY-----TDWFEVYNATRVPDSCCLEFS 174

Query: 180 SNCNGSLAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSR 239
            +C   L  P   +   C   V   LQE ++ V    L  A +Q+LG+  A  + C+  +
Sbjct: 175 ESC--GLHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFAMTMYCQVVK 232

Query: 240 DPAY 243
              Y
Sbjct: 233 ADTY 236


>gi|68800011 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score =  117 bits (293), Expect = 1e-26
 Identities = 72/244 (29%), Positives = 116/244 (47%), Gaps = 9/244 (3%)

Query: 1   MGQCGITSSKTVLVFLNLIFW-GAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIA 59
           M +  + + K ++   NL+FW G  G+L  VG ++  T   +        +L  A ++I 
Sbjct: 1   MARACLQAVKYLMFAFNLLFWLGGCGVLG-VGIWLAATQGSFATLSSSFPSLSAANLLII 59

Query: 60  VGALLFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSI 119
            GA +  IG +GC   I+E++C L TF ++LLLVF+ E  + +L + Y  K++    + +
Sbjct: 60  TGAFVMAIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDL 119

Query: 120 QKVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETA 179
           +K    Y        + A   +Q    CCG+ NY     TDWF+      VP SCC E +
Sbjct: 120 KKGLHLYGTQGNVGLTNAWSIIQTDFRCCGVSNY-----TDWFEVYNATRVPDSCCLEFS 174

Query: 180 SNCNGSLAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSR 239
            +C   L  P   +   C   V   LQE ++ V    L  A +Q+LG+  A  + C+  +
Sbjct: 175 ESC--GLHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFAMTMYCQVVK 232

Query: 240 DPAY 243
              Y
Sbjct: 233 ADTY 236


>gi|68799997 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score =  117 bits (293), Expect = 1e-26
 Identities = 72/244 (29%), Positives = 116/244 (47%), Gaps = 9/244 (3%)

Query: 1   MGQCGITSSKTVLVFLNLIFW-GAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIA 59
           M +  + + K ++   NL+FW G  G+L  VG ++  T   +        +L  A ++I 
Sbjct: 1   MARACLQAVKYLMFAFNLLFWLGGCGVLG-VGIWLAATQGSFATLSSSFPSLSAANLLII 59

Query: 60  VGALLFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSI 119
            GA +  IG +GC   I+E++C L TF ++LLLVF+ E  + +L + Y  K++    + +
Sbjct: 60  TGAFVMAIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDL 119

Query: 120 QKVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETA 179
           +K    Y        + A   +Q    CCG+ NY     TDWF+      VP SCC E +
Sbjct: 120 KKGLHLYGTQGNVGLTNAWSIIQTDFRCCGVSNY-----TDWFEVYNATRVPDSCCLEFS 174

Query: 180 SNCNGSLAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSR 239
            +C   L  P   +   C   V   LQE ++ V    L  A +Q+LG+  A  + C+  +
Sbjct: 175 ESC--GLHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFAMTMYCQVVK 232

Query: 240 DPAY 243
              Y
Sbjct: 233 ADTY 236


>gi|4502679 CD63 antigen isoform A [Homo sapiens]
          Length = 238

 Score =  114 bits (286), Expect = 6e-26
 Identities = 66/197 (33%), Positives = 108/197 (54%), Gaps = 9/197 (4%)

Query: 50  TLIPAVVIIAVGALLFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRA 109
           +L+P VVIIAVG  LF++  +GCC   +E+ C + TF I L L+ + EV   + GYV+R 
Sbjct: 51  SLLP-VVIIAVGVFLFLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRD 109

Query: 110 KVENEVDRSIQKVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQS 169
           KV +E + + ++  + Y   N  A+   +D +Q    CCG  NY+DWE      + +   
Sbjct: 110 KVMSEFNNNFRQQMENYPKNNHTAS--ILDRMQADFKCCGAANYTDWEKIPSMSKNR--- 164

Query: 170 VPLSCCRETASNCNGSLAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLC 229
           VP SCC      C G   +   ++ EGC   +   L++ ++ V  AAL  A +++LG++ 
Sbjct: 165 VPDSCCINVTVGC-GINFNEKAIHKEGCVEKIGGWLRKNVLVVAAAALGIAFVEVLGIVF 223

Query: 230 ACIVLCRRSRDPAYELL 246
           AC ++  +S    YE++
Sbjct: 224 ACCLV--KSIRSGYEVM 238


>gi|5729941 tetraspanin 9 [Homo sapiens]
          Length = 239

 Score =  110 bits (274), Expect = 2e-24
 Identities = 61/219 (27%), Positives = 112/219 (51%), Gaps = 9/219 (4%)

Query: 10  KTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAVGALLFIIGL 69
           K ++   NLIFW     L  VG ++ ++  ++  F     +L  A ++IA+G ++ + G 
Sbjct: 10  KYMMFLFNLIFWLCGCGLLGVGIWLSVSQGNFATFSPSFPSLSAANLVIAIGTIVMVTGF 69

Query: 70  IGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQKVYKTYNGT 129
           +GC   I+E++C L +F I+LL++ + E+++++L +VY  KV     + +++    Y+  
Sbjct: 70  LGCLGAIKENKCLLLSFFIVLLVILLAELILLILFFVYMDKVNENAKKDLKEGLLLYHTE 129

Query: 130 NPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETASNCNGSLAHP 189
           N      A + +Q ++ CCG+ +Y     TDW+      +VP  CC E +  C  +   P
Sbjct: 130 NNVGLKNAWNIIQAEMRCCGVTDY-----TDWYPVLGENTVPDRCCMENSQGCGRNATTP 184

Query: 190 SDLYAEGCEALVVKKLQEIMMHVI-WAALAFAAIQLLGM 227
             L+  GC    VK   +   HV+    +    +Q+LGM
Sbjct: 185 --LWRTGCYE-KVKMWFDDNKHVLGTVGMCILIMQILGM 220


>gi|91199546 CD63 antigen isoform B [Homo sapiens]
          Length = 236

 Score =  108 bits (270), Expect = 4e-24
 Identities = 66/197 (33%), Positives = 106/197 (53%), Gaps = 11/197 (5%)

Query: 50  TLIPAVVIIAVGALLFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRA 109
           +L+P VVIIAVG  LF++  +GCC   +E+ C + TF I L L+ + EV   + GYV+R 
Sbjct: 51  SLLP-VVIIAVGVFLFLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRD 109

Query: 110 KVENEVDRSIQKVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQS 169
           KV +E + + ++  + Y   N  A+   +D +Q    CCG  NY+DWE      + +   
Sbjct: 110 KVMSEFNNNFRQQMENYPKNNHTAS--ILDRMQADFKCCGAANYTDWEKIPSMSKNR--- 164

Query: 170 VPLSCCRETASNCNGSLAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLC 229
           VP SCC      C G   +   ++ EGC   +   L++ ++ V  AAL  A +  LG++ 
Sbjct: 165 VPDSCCINVTVGC-GINFNEKAIHKEGCVEKIGGWLRKNVLVVAAAALGIAFV--LGIVF 221

Query: 230 ACIVLCRRSRDPAYELL 246
           AC ++  +S    YE++
Sbjct: 222 ACCLV--KSIRSGYEVM 236


>gi|4504813 CD82 antigen isoform 1 [Homo sapiens]
          Length = 267

 Score =  105 bits (262), Expect = 4e-23
 Identities = 73/263 (27%), Positives = 115/263 (43%), Gaps = 22/263 (8%)

Query: 1   MGQCGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIP--AVVII 58
           MG   I  +K  L   NLIF+    ++   G ++      +    +   + +   A V I
Sbjct: 1   MGSACIKVTKYFLFLFNLIFFILGAVILGFGVWILADKSSFISVLQTSSSSLRMGAYVFI 60

Query: 59  AVGALLFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRS 118
            VGA+  ++G +GC   + E RC L  +   LLL+ + +V    L Y    K++ E+   
Sbjct: 61  GVGAVTMLMGFLGCIGAVNEVRCLLGLYFAFLLLILIAQVTAGALFYFNMGKLKQEMGGI 120

Query: 119 IQKVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSC---- 174
           + ++ + YN +  D+   A DYVQ Q+ CCG  ++ +W +          + P SC    
Sbjct: 121 VTELIRDYNSSREDSLQDAWDYVQAQVKCCGWVSFYNWTDNAELMNRPEVTYPCSCEVKG 180

Query: 175 ------------CRETASNCNGSLAHPSD--LYAEGCEALVVKKLQEIMMHVIWAALAFA 220
                       C E   N   S  HP D  +Y EGC   V   LQE +  ++   +  A
Sbjct: 181 EEDNSLSVRKGFC-EAPGNRTQSGNHPEDWPVYQEGCMEKVQAWLQENLGIILGVGVGVA 239

Query: 221 AIQLLGMLCACIVLCRRSRDPAY 243
            I+LLGM+ + I LCR      Y
Sbjct: 240 IIELLGMVLS-ICLCRHVHSEDY 261


>gi|122937466 tetraspanin 11 [Homo sapiens]
          Length = 253

 Score =  103 bits (256), Expect = 2e-22
 Identities = 59/235 (25%), Positives = 115/235 (48%), Gaps = 6/235 (2%)

Query: 10  KTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAVGALLFIIGL 69
           K +L   N  FW     +  VG +  +    Y            A ++I  G L+ + G 
Sbjct: 17  KYLLFVFNFFFWVGGAAVLAVGIWTLVEKSGYLSVLASSTFAASAYILIFAGVLVMVTGF 76

Query: 70  IGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQKVY-KTYNG 128
           +G  A + E +  L+T+  +LL++F+ E+V  VL +VY  ++ +E+ + + +   + Y  
Sbjct: 77  LGFGAILWERKGCLSTYFCLLLVIFLVELVAGVLAHVYYQRLSDELKQHLNRTLAENYGQ 136

Query: 129 TNPDAASRAIDYVQRQLHCCGIHNYSDWENTDW--FKETKNQSVPLSCCRETASNCNGSL 186
                 + ++D +Q+   CCG ++ +DW+++ +   +E + + VP SCC+     C G  
Sbjct: 137 PGATQITASVDRLQQDFKCCGSNSSADWQHSTYILLREAEGRQVPDSCCKTVVVRC-GQR 195

Query: 187 AHPSDLY--AEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSR 239
           AHPS++Y    GC   + + L + ++ +    +  A +Q+ GM+  C +  R  R
Sbjct: 196 AHPSNIYKVEGGCLTKLEQFLADHLLLMGAVGIGVACLQICGMVLTCCLHQRLQR 250


>gi|10834972 CD53 antigen [Homo sapiens]
          Length = 219

 Score =  103 bits (256), Expect = 2e-22
 Identities = 65/236 (27%), Positives = 109/236 (46%), Gaps = 27/236 (11%)

Query: 1   MGQCGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAV 60
           MG   +   K VL F NL+FW     +   G Y+ I ++++   F ++ +L    V + V
Sbjct: 1   MGMSSLKLLKYVLFFFNLLFWICGCCILGFGIYLLI-HNNFGVLFHNLPSLTLGNVFVIV 59

Query: 61  GALLFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQ 120
           G+++ ++  +GC  +I+E++C L +F I+LL++ + EV + +L +VY  K+   V + + 
Sbjct: 60  GSIIMVVAFLGCMGSIKENKCLLMSFFILLLIILLAEVTLAILLFVYEQKLNEYVAKGLT 119

Query: 121 KVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETAS 180
                Y+  N   A  A D +Q  L CCGI+  SDW              P SC      
Sbjct: 120 DSIHRYHSDNSTKA--AWDSIQSFLQCCGINGTSDW----------TSGPPASC------ 161

Query: 181 NCNGSLAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCR 236
                   PSD   EGC A          +++    +    I++LGM  A  + C+
Sbjct: 162 --------PSDRKVEGCYAKARLWFHSNFLYIGIITICVCVIEVLGMSFALTLNCQ 209


>gi|91106727 CD53 antigen [Homo sapiens]
          Length = 219

 Score =  103 bits (256), Expect = 2e-22
 Identities = 65/236 (27%), Positives = 109/236 (46%), Gaps = 27/236 (11%)

Query: 1   MGQCGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAV 60
           MG   +   K VL F NL+FW     +   G Y+ I ++++   F ++ +L    V + V
Sbjct: 1   MGMSSLKLLKYVLFFFNLLFWICGCCILGFGIYLLI-HNNFGVLFHNLPSLTLGNVFVIV 59

Query: 61  GALLFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQ 120
           G+++ ++  +GC  +I+E++C L +F I+LL++ + EV + +L +VY  K+   V + + 
Sbjct: 60  GSIIMVVAFLGCMGSIKENKCLLMSFFILLLIILLAEVTLAILLFVYEQKLNEYVAKGLT 119

Query: 121 KVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETAS 180
                Y+  N   A  A D +Q  L CCGI+  SDW              P SC      
Sbjct: 120 DSIHRYHSDNSTKA--AWDSIQSFLQCCGINGTSDW----------TSGPPASC------ 161

Query: 181 NCNGSLAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCR 236
                   PSD   EGC A          +++    +    I++LGM  A  + C+
Sbjct: 162 --------PSDRKVEGCYAKARLWFHSNFLYIGIITICVCVIEVLGMSFALTLNCQ 209


>gi|21264578 tetraspan 1 [Homo sapiens]
          Length = 241

 Score =  100 bits (250), Expect = 9e-22
 Identities = 66/236 (27%), Positives = 110/236 (46%), Gaps = 15/236 (6%)

Query: 10  KTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVV-----IIAVGALL 64
           KT+++  NL+ +     L  VG +V I    +   F  + +     V     +IA G ++
Sbjct: 8   KTMMILFNLLIFLCGAALLAVGIWVSIDGASFLKIFGPLSSSAMQFVNVGYFLIAAGVVV 67

Query: 65  FIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQKVYK 124
           F +G +GC     ES+C L TF  ILLL+F+ EV   V+  VY    E+ +   +    K
Sbjct: 68  FALGFLGCYGAKTESKCALVTFFFILLLIFIAEVAAAVVALVYTTMAEHFLTLLVVPAIK 127

Query: 125 TYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETASN--- 181
              G+  D  ++  +   + L CCG  NY+D+E++ +FKE  N + P  CC +  +N   
Sbjct: 128 KDYGSQED-FTQVWNTTMKGLKCCGFTNYTDFEDSPYFKE--NSAFPPFCCNDNVTNTAN 184

Query: 182 --CNGSLAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLC 235
             C    AH  D   EGC   ++  ++   + V   A     ++L  M+ +  + C
Sbjct: 185 ETCTKQKAH--DQKVEGCFNQLLYDIRTNAVTVGGVAAGIGGLELAAMIVSMYLYC 238


>gi|68800032 tetraspanin 4 isoform b [Homo sapiens]
          Length = 174

 Score = 97.8 bits (242), Expect = 8e-21
 Identities = 55/177 (31%), Positives = 85/177 (48%), Gaps = 7/177 (3%)

Query: 67  IGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQKVYKTY 126
           IG +GC   I+E++C L TF ++LLLVF+ E  + +L + Y  K++    + ++K    Y
Sbjct: 3   IGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHLY 62

Query: 127 NGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETASNCNGSL 186
                   + A   +Q    CCG+ NY     TDWF+      VP SCC E + +C   L
Sbjct: 63  GTQGNVGLTNAWSIIQTDFRCCGVSNY-----TDWFEVYNATRVPDSCCLEFSESC--GL 115

Query: 187 AHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSRDPAY 243
             P   +   C   V   LQE ++ V    L  A +Q+LG+  A  + C+  +   Y
Sbjct: 116 HAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFAMTMYCQVVKADTY 172


>gi|4759238 transmembrane 4 superfamily member 3 [Homo sapiens]
          Length = 237

 Score = 94.7 bits (234), Expect = 7e-20
 Identities = 64/227 (28%), Positives = 113/227 (49%), Gaps = 16/227 (7%)

Query: 17  NLIFWGAAGILCYVGAYVFITYDDYDHF-FEDV--YTLIPAVVIIAVGALLFIIGLIGCC 73
           N +FW    ++  +  +V ++ D    F  EDV   + +   ++IAVGA++ I+G +GCC
Sbjct: 16  NFLFWLCGILILALAIWVRVSNDSQAIFGSEDVGSSSYVAVDILIAVGAIIMILGFLGCC 75

Query: 74  ATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQKVYKTYNGTNPDA 133
             I+ESRC L  F I LLL+ + +V   +LG V+++K +  V+ ++ +  K  + T    
Sbjct: 76  GAIKESRCMLLLFFIGLLLILLLQVATGILGAVFKSKSDRIVNETLYENTKLLSATGESE 135

Query: 134 A--SRAIDYVQRQLHCCGIHN-YSDWENTDWFKETKNQSVPLSC-CRETASNCNGSLAHP 189
                AI   Q +  CCG+ N  +DW N         Q  P  C C +    C     + 
Sbjct: 136 KQFQEAIIVFQEEFKCCGLVNGAADWGN-------NFQHYPELCACLDKQRPCQS--YNG 186

Query: 190 SDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCR 236
             +Y E C + +   L + ++ VI  +   A I++LG++ + ++ C+
Sbjct: 187 KQVYKETCISFIKDFLAKNLIIVIGISFGLAVIEILGLVFSMVLYCQ 233


>gi|30425534 tetraspanin 33 [Homo sapiens]
          Length = 283

 Score = 94.4 bits (233), Expect = 9e-20
 Identities = 65/243 (26%), Positives = 110/243 (45%), Gaps = 22/243 (9%)

Query: 10  KTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAVGALLFIIGL 69
           K +L F N++FW  + ++  VG Y  +    +         + PA+++I VG L+F++  
Sbjct: 23  KYLLFFFNMLFWVISMVMVAVGVYARLM--KHAEAALACLAVDPAILLIVVGVLMFLLTF 80

Query: 70  IGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQKVYKTYNGT 129
            GC  ++RE+ C L TF + L  VF+ ++   +LG+V+  K   +V   I      Y   
Sbjct: 81  CGCIGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSDKARGKVSEIINNAIVHYR-- 138

Query: 130 NPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQ------SVPLSCCRETASN-- 181
           +       ID+ Q++  CCG  +Y DW    +F  +++       SVP SCC  T     
Sbjct: 139 DDLDLQNLIDFGQKKFSCCGGISYKDWSQNMYFNCSEDNPSRERCSVPYSCCLPTPDQAV 198

Query: 182 ----CNGS------LAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCAC 231
               C         L     +Y  GC   +V  +   +  +   AL  A  QL+G+L + 
Sbjct: 199 INTMCGQGMQAFDYLEASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVGILLSQ 258

Query: 232 IVL 234
           I++
Sbjct: 259 ILV 261


>gi|42476204 tetraspanin 18 isoform 2 [Homo sapiens]
          Length = 248

 Score = 92.4 bits (228), Expect = 3e-19
 Identities = 61/241 (25%), Positives = 113/241 (46%), Gaps = 15/241 (6%)

Query: 2   GQCGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFE-DVYTLIPAVVIIAV 60
           G C       + VF   IF G A +L  +G +V +    +      +   L  A +++A+
Sbjct: 3   GDCLSCMKYLMFVFNFFIFLGGACLLA-IGIWVMVDPTGFREIVAANPLLLTGAYILLAM 61

Query: 61  GALLFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQ 120
           G LLF++G +GCC  +RE++C L  F + +L++F+ E+   +L +++R  +  E     +
Sbjct: 62  GGLLFLLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLTREF--FTK 119

Query: 121 KVYKTYNGTN-PDAASRAIDYVQRQLHCCGIHNYSDWENTDWFK--ETKNQSVPLSCCRE 177
           ++ K Y G N  D  S   + V     CCG++   D++    F+     ++ VP +CCR 
Sbjct: 120 ELTKHYQGNNDTDIFSATWNSVMITFGCCGVNGPEDFKFASVFRLLTLDSEEVPEACCRR 179

Query: 178 TASNCNGSLAHPSD--------LYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLC 229
              + +G L    +        L  +GC  +++   +  +      A+   AI+L  M+ 
Sbjct: 180 EPQSRDGVLLSREECLLGRSLFLNKQGCYTVILNTFETYVYLAGALAIGVLAIELFAMIF 239

Query: 230 A 230
           A
Sbjct: 240 A 240


>gi|72534746 tetraspanin 18 isoform 1 [Homo sapiens]
          Length = 267

 Score = 87.8 bits (216), Expect = 8e-18
 Identities = 58/234 (24%), Positives = 109/234 (46%), Gaps = 15/234 (6%)

Query: 2   GQCGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFE-DVYTLIPAVVIIAV 60
           G C       + VF   IF G A +L  +G +V +    +      +   L  A +++A+
Sbjct: 3   GDCLSCMKYLMFVFNFFIFLGGACLLA-IGIWVMVDPTGFREIVAANPLLLTGAYILLAM 61

Query: 61  GALLFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQ 120
           G LLF++G +GCC  +RE++C L  F + +L++F+ E+   +L +++R  +  E     +
Sbjct: 62  GGLLFLLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLTREF--FTK 119

Query: 121 KVYKTYNGTN-PDAASRAIDYVQRQLHCCGIHNYSDWENTDWFK--ETKNQSVPLSCCRE 177
           ++ K Y G N  D  S   + V     CCG++   D++    F+     ++ VP +CCR 
Sbjct: 120 ELTKHYQGNNDTDVFSATWNSVMITFGCCGVNGPEDFKFASVFRLLTLDSEEVPEACCRR 179

Query: 178 TASNCNGSLAHPSD--------LYAEGCEALVVKKLQEIMMHVIWAALAFAAIQ 223
              + +G L    +        L  +GC  +++   +  +      A+   AI+
Sbjct: 180 EPQSRDGVLLSREECLLGRSLFLNKQGCYTVILNTFETYVYLAGALAIGVLAIE 233


>gi|4502663 CD37 antigen isoform A [Homo sapiens]
          Length = 281

 Score = 87.0 bits (214), Expect = 1e-17
 Identities = 71/259 (27%), Positives = 116/259 (44%), Gaps = 34/259 (13%)

Query: 10  KTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIP--AVVIIAVGALLFII 67
           K  L   NL F+    ++   G ++ I    +  F    +  +   + V+   G     I
Sbjct: 12  KYFLFVFNLFFFVLGSLIFCFGIWILIDKTSFVSFVGLAFVPLQIWSKVLAISGIFTMGI 71

Query: 68  GLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQKVYKTYN 127
            L+GC   ++E RC L  +  +LLL+F T++ + +L    RA++E  +   ++K  + Y 
Sbjct: 72  ALLGCVGALKELRCLLGLYFGMLLLLFATQITLGILISTQRAQLERSLRDVVEKTIQKY- 130

Query: 128 GTNPD--AASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQS--VPLSCCRETASNCN 183
           GTNP+  AA  + DYVQ QL CCG H   DW      +   +++  VP SC   +A+N +
Sbjct: 131 GTNPEETAAEESWDYVQFQLRCCGWHYPQDWFQVLILRGNGSEAHRVPCSCYNLSATNDS 190

Query: 184 --------------GSLA---HPSD---------LYAEGCEALVVKKLQEIMMHVIWAAL 217
                         G LA   H +D         +Y EGC   + K L   ++ ++   L
Sbjct: 191 TILDKVILPQLSRLGHLARSRHSADICAVPAESHIYREGCAQGLQKWLHNNLISIVGICL 250

Query: 218 AFAAIQLLGMLCACIVLCR 236
               ++ LG +   I LCR
Sbjct: 251 GVGLLE-LGFMTLSIFLCR 268


>gi|91807110 CD37 antigen isoform B [Homo sapiens]
          Length = 213

 Score = 82.0 bits (201), Expect = 4e-16
 Identities = 61/200 (30%), Positives = 96/200 (48%), Gaps = 32/200 (16%)

Query: 67  IGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQKVYKTY 126
           I L+GC   ++E RC L  +  +LLL+F T++ + +L    RA++E  +   ++K  + Y
Sbjct: 3   IALLGCVGALKELRCLLGLYFGMLLLLFATQITLGILISTQRAQLERSLRDVVEKTIQKY 62

Query: 127 NGTNPD--AASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQS--VPLSCCRETASNC 182
            GTNP+  AA  + DYVQ QL CCG H   DW      +   +++  VP SC   +A+N 
Sbjct: 63  -GTNPEETAAEESWDYVQFQLRCCGWHYPQDWFQVLILRGNGSEAHRVPCSCYNLSATND 121

Query: 183 N--------------GSLA---HPSD---------LYAEGCEALVVKKLQEIMMHVIWAA 216
           +              G LA   H +D         +Y EGC   + K L   ++ ++   
Sbjct: 122 STILDKVILPQLSRLGHLARSRHSADICAVPAESHIYREGCAQGLQKWLHNNLISIVGIC 181

Query: 217 LAFAAIQLLGMLCACIVLCR 236
           L    ++ LG +   I LCR
Sbjct: 182 LGVGLLE-LGFMTLSIFLCR 200


>gi|67782354 CD82 antigen isoform 2 [Homo sapiens]
          Length = 242

 Score = 79.7 bits (195), Expect = 2e-15
 Identities = 66/263 (25%), Positives = 104/263 (39%), Gaps = 47/263 (17%)

Query: 1   MGQCGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIP--AVVII 58
           MG   I  +K  L   NLIF+    ++   G ++      +    +   + +   A V I
Sbjct: 1   MGSACIKVTKYFLFLFNLIFFILGAVILGFGVWILADKSSFISVLQTSSSSLRMGAYVFI 60

Query: 59  AVGALLFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRS 118
            VGA+  ++G +GC   + E RC L                           ++ E+   
Sbjct: 61  GVGAVTMLMGFLGCIGAVNEVRCLLGL-------------------------LKQEMGGI 95

Query: 119 IQKVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSC---- 174
           + ++ + YN +  D+   A DYVQ Q+ CCG  ++ +W +          + P SC    
Sbjct: 96  VTELIRDYNSSREDSLQDAWDYVQAQVKCCGWVSFYNWTDNAELMNRPEVTYPCSCEVKG 155

Query: 175 ------------CRETASNCNGSLAHPSD--LYAEGCEALVVKKLQEIMMHVIWAALAFA 220
                       C E   N   S  HP D  +Y EGC   V   LQE +  ++   +  A
Sbjct: 156 EEDNSLSVRKGFC-EAPGNRTQSGNHPEDWPVYQEGCMEKVQAWLQENLGIILGVGVGVA 214

Query: 221 AIQLLGMLCACIVLCRRSRDPAY 243
            I+LLGM+ + I LCR      Y
Sbjct: 215 IIELLGMVLS-ICLCRHVHSEDY 236


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.328    0.141    0.448 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,927,305
Number of Sequences: 37866
Number of extensions: 351808
Number of successful extensions: 1368
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 47
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1237
Number of HSP's gapped (non-prelim): 58
length of query: 253
length of database: 18,247,518
effective HSP length: 100
effective length of query: 153
effective length of database: 14,460,918
effective search space: 2212520454
effective search space used: 2212520454
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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