Guide to the Human Genome
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Search of human proteins with 5032189

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5032189 tumor protein p53 binding protein 1 isoform 3 [Homo
sapiens]
         (1972 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|213972636 tumor protein p53 binding protein 1 isoform 1 [Homo...  3925   0.0  
gi|5032189 tumor protein p53 binding protein 1 isoform 3 [Homo s...  3925   0.0  
gi|213972634 tumor protein p53 binding protein 1 isoform 2 [Homo...  3917   0.0  
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    74   2e-12
gi|91982772 mucin 17 [Homo sapiens]                                    71   9e-12
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     68   1e-10
gi|150170670 piccolo isoform 2 [Homo sapiens]                          67   2e-10
gi|150378539 piccolo isoform 1 [Homo sapiens]                          67   2e-10
gi|209862789 microtubule associated monoxygenase, calponin and L...    60   2e-08
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)...    60   2e-08
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)...    60   2e-08
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)...    60   2e-08
gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]                         59   6e-08
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]              57   2e-07
gi|87299628 biorientation of chromosomes in cell division 1-like...    53   3e-06
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        53   3e-06
gi|62241003 cardiomyopathy associated 5 [Homo sapiens]                 53   3e-06
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ...    51   1e-05
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ...    51   1e-05
gi|148806908 fibronectin type III domain containing 1 [Homo sapi...    51   1e-05
gi|226437579 NAC alpha domain containing [Homo sapiens]                50   3e-05
gi|239743134 PREDICTED: NAC alpha domain containing [Homo sapiens]     50   3e-05
gi|41281453 serine/threonine kinase 2 [Homo sapiens]                   49   6e-05
gi|210032580 SET domain containing 1B [Homo sapiens]                   48   1e-04
gi|239749105 PREDICTED: NAC alpha domain containing [Homo sapiens]     47   2e-04
gi|239508792 PREDICTED: NAC alpha domain containing [Homo sapiens]     47   2e-04
gi|38201621 eukaryotic translation initiation factor 4 gamma, 1 ...    47   2e-04
gi|38201627 eukaryotic translation initiation factor 4 gamma, 1 ...    47   2e-04
gi|38201623 eukaryotic translation initiation factor 4 gamma, 1 ...    47   2e-04
gi|11968023 zinc finger protein 106 homolog [Homo sapiens]             47   2e-04

>gi|213972636 tumor protein p53 binding protein 1 isoform 1 [Homo
            sapiens]
          Length = 1977

 Score = 3925 bits (10180), Expect = 0.0
 Identities = 1972/1972 (100%), Positives = 1972/1972 (100%)

Query: 1    MDPTGSQLDSDFSQQDTPCLIIEDSQPESQVLEDDSGSHFSMLSRHLPNLQTHKENPVLD 60
            MDPTGSQLDSDFSQQDTPCLIIEDSQPESQVLEDDSGSHFSMLSRHLPNLQTHKENPVLD
Sbjct: 6    MDPTGSQLDSDFSQQDTPCLIIEDSQPESQVLEDDSGSHFSMLSRHLPNLQTHKENPVLD 65

Query: 61   VVSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPNRTSSV 120
            VVSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPNRTSSV
Sbjct: 66   VVSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPNRTSSV 125

Query: 121  LGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQSQD 180
            LGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQSQD
Sbjct: 126  LGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQSQD 185

Query: 181  VEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTA 240
            VEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTA
Sbjct: 186  VEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTA 245

Query: 241  QPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSPEPEVL 300
            QPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSPEPEVL
Sbjct: 246  QPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSPEPEVL 305

Query: 301  STQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSLSTNSS 360
            STQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSLSTNSS
Sbjct: 306  STQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSLSTNSS 365

Query: 361  DLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELENP 420
            DLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELENP
Sbjct: 366  DLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELENP 425

Query: 421  PLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGKKDGDM 480
            PLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGKKDGDM
Sbjct: 426  PLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGKKDGDM 485

Query: 481  HSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHRIDEDG 540
            HSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHRIDEDG
Sbjct: 486  HSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHRIDEDG 545

Query: 541  ENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDISIL 600
            ENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDISIL
Sbjct: 546  ENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDISIL 605

Query: 601  ATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEGSS 660
            ATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEGSS
Sbjct: 606  ATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEGSS 665

Query: 661  GSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSEAMEVET 720
            GSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSEAMEVET
Sbjct: 666  GSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSEAMEVET 725

Query: 721  SVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPLEGVEK 780
            SVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPLEGVEK
Sbjct: 726  SVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPLEGVEK 785

Query: 781  CSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSLPLVRA 840
            CSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSLPLVRA
Sbjct: 786  CSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSLPLVRA 845

Query: 841  DDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSFCESSS 900
            DDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSFCESSS
Sbjct: 846  DDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSFCESSS 905

Query: 901  ETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDVMSESM 960
            ETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDVMSESM
Sbjct: 906  ETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDVMSESM 965

Query: 961  VETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGERKNGST 1020
            VETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGERKNGST
Sbjct: 966  VETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGERKNGST 1025

Query: 1021 AVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKEKLEGD 1080
            AVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKEKLEGD
Sbjct: 1026 AVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKEKLEGD 1085

Query: 1081 HTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVTDVLEDQKEGRSTNKENPS 1140
            HTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVTDVLEDQKEGRSTNKENPS
Sbjct: 1086 HTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVTDVLEDQKEGRSTNKENPS 1145

Query: 1141 KALIERPSQNNIGIQTMECSLRVPETVSAATQTIKNVCEQGTSTVDQNFGKQDATVQTER 1200
            KALIERPSQNNIGIQTMECSLRVPETVSAATQTIKNVCEQGTSTVDQNFGKQDATVQTER
Sbjct: 1146 KALIERPSQNNIGIQTMECSLRVPETVSAATQTIKNVCEQGTSTVDQNFGKQDATVQTER 1205

Query: 1201 GSGEKPVSAPGDDTESLHSQGEEEFDMPQPPHGHVLHRHMRTIREVRTLVTRVITDVYYV 1260
            GSGEKPVSAPGDDTESLHSQGEEEFDMPQPPHGHVLHRHMRTIREVRTLVTRVITDVYYV
Sbjct: 1206 GSGEKPVSAPGDDTESLHSQGEEEFDMPQPPHGHVLHRHMRTIREVRTLVTRVITDVYYV 1265

Query: 1261 DGTEVERKVTEETEEPIVECQECETEVSPSQTGGSSGDLGDISSFSSKASSLHRTSSGTS 1320
            DGTEVERKVTEETEEPIVECQECETEVSPSQTGGSSGDLGDISSFSSKASSLHRTSSGTS
Sbjct: 1266 DGTEVERKVTEETEEPIVECQECETEVSPSQTGGSSGDLGDISSFSSKASSLHRTSSGTS 1325

Query: 1321 LSAMHSSGSSGKGAGPLRGKTSGTEPADFALPSSRGGPGKLSPRKGVSQTGTPVCEEDGD 1380
            LSAMHSSGSSGKGAGPLRGKTSGTEPADFALPSSRGGPGKLSPRKGVSQTGTPVCEEDGD
Sbjct: 1326 LSAMHSSGSSGKGAGPLRGKTSGTEPADFALPSSRGGPGKLSPRKGVSQTGTPVCEEDGD 1385

Query: 1381 AGLGIRQGGKAPVTPRGRGRRGRPPSRTTGTRETAVPGPLGIEDISPNLSPDDKSFSRVV 1440
            AGLGIRQGGKAPVTPRGRGRRGRPPSRTTGTRETAVPGPLGIEDISPNLSPDDKSFSRVV
Sbjct: 1386 AGLGIRQGGKAPVTPRGRGRRGRPPSRTTGTRETAVPGPLGIEDISPNLSPDDKSFSRVV 1445

Query: 1441 PRVPDSTRRTDVGAGALRRSDSPEIPFQAAAGPSDGLDASSPGNSFVGLRVVAKWSSNGY 1500
            PRVPDSTRRTDVGAGALRRSDSPEIPFQAAAGPSDGLDASSPGNSFVGLRVVAKWSSNGY
Sbjct: 1446 PRVPDSTRRTDVGAGALRRSDSPEIPFQAAAGPSDGLDASSPGNSFVGLRVVAKWSSNGY 1505

Query: 1501 FYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSAGVVKG 1560
            FYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSAGVVKG
Sbjct: 1506 FYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSAGVVKG 1565

Query: 1561 HRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLGPYEAVTPLTKAADISLD 1620
            HRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLGPYEAVTPLTKAADISLD
Sbjct: 1566 HRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLGPYEAVTPLTKAADISLD 1625

Query: 1621 NLVEGKRKRRSNVSSPATPTASSSSSTTPTRKITESPRASMGVLSGKRKLITSEEERSPA 1680
            NLVEGKRKRRSNVSSPATPTASSSSSTTPTRKITESPRASMGVLSGKRKLITSEEERSPA
Sbjct: 1626 NLVEGKRKRRSNVSSPATPTASSSSSTTPTRKITESPRASMGVLSGKRKLITSEEERSPA 1685

Query: 1681 KRGRKSATVKPGAVGAGEFVSPCESGDNTGEPSALEEQRGPLPLNKTLFLGYAFLLTMAT 1740
            KRGRKSATVKPGAVGAGEFVSPCESGDNTGEPSALEEQRGPLPLNKTLFLGYAFLLTMAT
Sbjct: 1686 KRGRKSATVKPGAVGAGEFVSPCESGDNTGEPSALEEQRGPLPLNKTLFLGYAFLLTMAT 1745

Query: 1741 TSDKLASRSKLPDGPTGSSEEEEEFLEIPPFNKQYTESQLRAGAGYILEDFNEAQCNTAY 1800
            TSDKLASRSKLPDGPTGSSEEEEEFLEIPPFNKQYTESQLRAGAGYILEDFNEAQCNTAY
Sbjct: 1746 TSDKLASRSKLPDGPTGSSEEEEEFLEIPPFNKQYTESQLRAGAGYILEDFNEAQCNTAY 1805

Query: 1801 QCLLIADQHCRTRKYFLCLASGIPCVSHVWVHDSCHANQLQNYRNYLLPAGYSLEEQRIL 1860
            QCLLIADQHCRTRKYFLCLASGIPCVSHVWVHDSCHANQLQNYRNYLLPAGYSLEEQRIL
Sbjct: 1806 QCLLIADQHCRTRKYFLCLASGIPCVSHVWVHDSCHANQLQNYRNYLLPAGYSLEEQRIL 1865

Query: 1861 DWQPRENPFQNLKVLLVSDQQQNFLELWSEILMTGGAASVKQHHSSAHNKDIALGVFDVV 1920
            DWQPRENPFQNLKVLLVSDQQQNFLELWSEILMTGGAASVKQHHSSAHNKDIALGVFDVV
Sbjct: 1866 DWQPRENPFQNLKVLLVSDQQQNFLELWSEILMTGGAASVKQHHSSAHNKDIALGVFDVV 1925

Query: 1921 VTDPSCPASVLKCAEALQLPVVSQEWVIQCLIVGERIGFKQHPKYKHDYVSH 1972
            VTDPSCPASVLKCAEALQLPVVSQEWVIQCLIVGERIGFKQHPKYKHDYVSH
Sbjct: 1926 VTDPSCPASVLKCAEALQLPVVSQEWVIQCLIVGERIGFKQHPKYKHDYVSH 1977


>gi|5032189 tumor protein p53 binding protein 1 isoform 3 [Homo
            sapiens]
          Length = 1972

 Score = 3925 bits (10180), Expect = 0.0
 Identities = 1972/1972 (100%), Positives = 1972/1972 (100%)

Query: 1    MDPTGSQLDSDFSQQDTPCLIIEDSQPESQVLEDDSGSHFSMLSRHLPNLQTHKENPVLD 60
            MDPTGSQLDSDFSQQDTPCLIIEDSQPESQVLEDDSGSHFSMLSRHLPNLQTHKENPVLD
Sbjct: 1    MDPTGSQLDSDFSQQDTPCLIIEDSQPESQVLEDDSGSHFSMLSRHLPNLQTHKENPVLD 60

Query: 61   VVSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPNRTSSV 120
            VVSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPNRTSSV
Sbjct: 61   VVSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPNRTSSV 120

Query: 121  LGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQSQD 180
            LGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQSQD
Sbjct: 121  LGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQSQD 180

Query: 181  VEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTA 240
            VEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTA
Sbjct: 181  VEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTA 240

Query: 241  QPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSPEPEVL 300
            QPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSPEPEVL
Sbjct: 241  QPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSPEPEVL 300

Query: 301  STQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSLSTNSS 360
            STQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSLSTNSS
Sbjct: 301  STQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSLSTNSS 360

Query: 361  DLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELENP 420
            DLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELENP
Sbjct: 361  DLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELENP 420

Query: 421  PLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGKKDGDM 480
            PLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGKKDGDM
Sbjct: 421  PLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGKKDGDM 480

Query: 481  HSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHRIDEDG 540
            HSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHRIDEDG
Sbjct: 481  HSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHRIDEDG 540

Query: 541  ENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDISIL 600
            ENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDISIL
Sbjct: 541  ENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDISIL 600

Query: 601  ATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEGSS 660
            ATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEGSS
Sbjct: 601  ATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEGSS 660

Query: 661  GSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSEAMEVET 720
            GSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSEAMEVET
Sbjct: 661  GSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSEAMEVET 720

Query: 721  SVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPLEGVEK 780
            SVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPLEGVEK
Sbjct: 721  SVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPLEGVEK 780

Query: 781  CSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSLPLVRA 840
            CSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSLPLVRA
Sbjct: 781  CSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSLPLVRA 840

Query: 841  DDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSFCESSS 900
            DDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSFCESSS
Sbjct: 841  DDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSFCESSS 900

Query: 901  ETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDVMSESM 960
            ETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDVMSESM
Sbjct: 901  ETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDVMSESM 960

Query: 961  VETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGERKNGST 1020
            VETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGERKNGST
Sbjct: 961  VETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGERKNGST 1020

Query: 1021 AVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKEKLEGD 1080
            AVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKEKLEGD
Sbjct: 1021 AVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKEKLEGD 1080

Query: 1081 HTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVTDVLEDQKEGRSTNKENPS 1140
            HTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVTDVLEDQKEGRSTNKENPS
Sbjct: 1081 HTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVTDVLEDQKEGRSTNKENPS 1140

Query: 1141 KALIERPSQNNIGIQTMECSLRVPETVSAATQTIKNVCEQGTSTVDQNFGKQDATVQTER 1200
            KALIERPSQNNIGIQTMECSLRVPETVSAATQTIKNVCEQGTSTVDQNFGKQDATVQTER
Sbjct: 1141 KALIERPSQNNIGIQTMECSLRVPETVSAATQTIKNVCEQGTSTVDQNFGKQDATVQTER 1200

Query: 1201 GSGEKPVSAPGDDTESLHSQGEEEFDMPQPPHGHVLHRHMRTIREVRTLVTRVITDVYYV 1260
            GSGEKPVSAPGDDTESLHSQGEEEFDMPQPPHGHVLHRHMRTIREVRTLVTRVITDVYYV
Sbjct: 1201 GSGEKPVSAPGDDTESLHSQGEEEFDMPQPPHGHVLHRHMRTIREVRTLVTRVITDVYYV 1260

Query: 1261 DGTEVERKVTEETEEPIVECQECETEVSPSQTGGSSGDLGDISSFSSKASSLHRTSSGTS 1320
            DGTEVERKVTEETEEPIVECQECETEVSPSQTGGSSGDLGDISSFSSKASSLHRTSSGTS
Sbjct: 1261 DGTEVERKVTEETEEPIVECQECETEVSPSQTGGSSGDLGDISSFSSKASSLHRTSSGTS 1320

Query: 1321 LSAMHSSGSSGKGAGPLRGKTSGTEPADFALPSSRGGPGKLSPRKGVSQTGTPVCEEDGD 1380
            LSAMHSSGSSGKGAGPLRGKTSGTEPADFALPSSRGGPGKLSPRKGVSQTGTPVCEEDGD
Sbjct: 1321 LSAMHSSGSSGKGAGPLRGKTSGTEPADFALPSSRGGPGKLSPRKGVSQTGTPVCEEDGD 1380

Query: 1381 AGLGIRQGGKAPVTPRGRGRRGRPPSRTTGTRETAVPGPLGIEDISPNLSPDDKSFSRVV 1440
            AGLGIRQGGKAPVTPRGRGRRGRPPSRTTGTRETAVPGPLGIEDISPNLSPDDKSFSRVV
Sbjct: 1381 AGLGIRQGGKAPVTPRGRGRRGRPPSRTTGTRETAVPGPLGIEDISPNLSPDDKSFSRVV 1440

Query: 1441 PRVPDSTRRTDVGAGALRRSDSPEIPFQAAAGPSDGLDASSPGNSFVGLRVVAKWSSNGY 1500
            PRVPDSTRRTDVGAGALRRSDSPEIPFQAAAGPSDGLDASSPGNSFVGLRVVAKWSSNGY
Sbjct: 1441 PRVPDSTRRTDVGAGALRRSDSPEIPFQAAAGPSDGLDASSPGNSFVGLRVVAKWSSNGY 1500

Query: 1501 FYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSAGVVKG 1560
            FYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSAGVVKG
Sbjct: 1501 FYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSAGVVKG 1560

Query: 1561 HRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLGPYEAVTPLTKAADISLD 1620
            HRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLGPYEAVTPLTKAADISLD
Sbjct: 1561 HRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLGPYEAVTPLTKAADISLD 1620

Query: 1621 NLVEGKRKRRSNVSSPATPTASSSSSTTPTRKITESPRASMGVLSGKRKLITSEEERSPA 1680
            NLVEGKRKRRSNVSSPATPTASSSSSTTPTRKITESPRASMGVLSGKRKLITSEEERSPA
Sbjct: 1621 NLVEGKRKRRSNVSSPATPTASSSSSTTPTRKITESPRASMGVLSGKRKLITSEEERSPA 1680

Query: 1681 KRGRKSATVKPGAVGAGEFVSPCESGDNTGEPSALEEQRGPLPLNKTLFLGYAFLLTMAT 1740
            KRGRKSATVKPGAVGAGEFVSPCESGDNTGEPSALEEQRGPLPLNKTLFLGYAFLLTMAT
Sbjct: 1681 KRGRKSATVKPGAVGAGEFVSPCESGDNTGEPSALEEQRGPLPLNKTLFLGYAFLLTMAT 1740

Query: 1741 TSDKLASRSKLPDGPTGSSEEEEEFLEIPPFNKQYTESQLRAGAGYILEDFNEAQCNTAY 1800
            TSDKLASRSKLPDGPTGSSEEEEEFLEIPPFNKQYTESQLRAGAGYILEDFNEAQCNTAY
Sbjct: 1741 TSDKLASRSKLPDGPTGSSEEEEEFLEIPPFNKQYTESQLRAGAGYILEDFNEAQCNTAY 1800

Query: 1801 QCLLIADQHCRTRKYFLCLASGIPCVSHVWVHDSCHANQLQNYRNYLLPAGYSLEEQRIL 1860
            QCLLIADQHCRTRKYFLCLASGIPCVSHVWVHDSCHANQLQNYRNYLLPAGYSLEEQRIL
Sbjct: 1801 QCLLIADQHCRTRKYFLCLASGIPCVSHVWVHDSCHANQLQNYRNYLLPAGYSLEEQRIL 1860

Query: 1861 DWQPRENPFQNLKVLLVSDQQQNFLELWSEILMTGGAASVKQHHSSAHNKDIALGVFDVV 1920
            DWQPRENPFQNLKVLLVSDQQQNFLELWSEILMTGGAASVKQHHSSAHNKDIALGVFDVV
Sbjct: 1861 DWQPRENPFQNLKVLLVSDQQQNFLELWSEILMTGGAASVKQHHSSAHNKDIALGVFDVV 1920

Query: 1921 VTDPSCPASVLKCAEALQLPVVSQEWVIQCLIVGERIGFKQHPKYKHDYVSH 1972
            VTDPSCPASVLKCAEALQLPVVSQEWVIQCLIVGERIGFKQHPKYKHDYVSH
Sbjct: 1921 VTDPSCPASVLKCAEALQLPVVSQEWVIQCLIVGERIGFKQHPKYKHDYVSH 1972


>gi|213972634 tumor protein p53 binding protein 1 isoform 2 [Homo
            sapiens]
          Length = 1975

 Score = 3917 bits (10157), Expect = 0.0
 Identities = 1970/1972 (99%), Positives = 1970/1972 (99%), Gaps = 2/1972 (0%)

Query: 1    MDPTGSQLDSDFSQQDTPCLIIEDSQPESQVLEDDSGSHFSMLSRHLPNLQTHKENPVLD 60
            MDPTGSQLDSDFSQQDTPCLIIEDSQPESQVLEDDSGSHFSMLSRHLPNLQTHKENPVLD
Sbjct: 6    MDPTGSQLDSDFSQQDTPCLIIEDSQPESQVLEDDSGSHFSMLSRHLPNLQTHKENPVLD 65

Query: 61   VVSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPNRTSSV 120
            VVSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPNRTSSV
Sbjct: 66   VVSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPNRTSSV 125

Query: 121  LGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQSQD 180
            LGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQSQD
Sbjct: 126  LGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQSQD 185

Query: 181  VEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTA 240
            VEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTA
Sbjct: 186  VEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTA 245

Query: 241  QPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSPEPEVL 300
            QPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSPEPEVL
Sbjct: 246  QPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSPEPEVL 305

Query: 301  STQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSLSTNSS 360
            STQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSLSTNSS
Sbjct: 306  STQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSLSTNSS 365

Query: 361  DLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELENP 420
            DLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELENP
Sbjct: 366  DLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELENP 425

Query: 421  PLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGKKDGDM 480
            PLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGKKDGDM
Sbjct: 426  PLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGKKDGDM 485

Query: 481  HSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHRIDEDG 540
            HSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHRIDEDG
Sbjct: 486  HSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHRIDEDG 545

Query: 541  ENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDISIL 600
            ENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDISIL
Sbjct: 546  ENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDISIL 605

Query: 601  ATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEGSS 660
            ATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEGSS
Sbjct: 606  ATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEGSS 665

Query: 661  GSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSEAMEVET 720
            GSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSEAMEVET
Sbjct: 666  GSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSEAMEVET 725

Query: 721  SVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPLEGVEK 780
            SVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPLEGVEK
Sbjct: 726  SVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPLEGVEK 785

Query: 781  CSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSLPLVRA 840
            CSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSLPLVRA
Sbjct: 786  CSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSLPLVRA 845

Query: 841  DDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSFCESSS 900
            DDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSFCESSS
Sbjct: 846  DDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSFCESSS 905

Query: 901  ETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDVMSESM 960
            ETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDVMSESM
Sbjct: 906  ETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDVMSESM 965

Query: 961  VETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGERKNGST 1020
            VETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGERKNGST
Sbjct: 966  VETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGERKNGST 1025

Query: 1021 AVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKEKLEGD 1080
            AVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKEKLEGD
Sbjct: 1026 AVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKEKLEGD 1085

Query: 1081 HTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVTDVLEDQKEGRSTNKENPS 1140
            HTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVTDVLEDQKEGRSTNKENPS
Sbjct: 1086 HTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVTDVLEDQKEGRSTNKENPS 1145

Query: 1141 KALIERPSQNNIGIQTMECSLRVPETVSAATQTIKNVCEQGTSTVDQNFGKQDATVQTER 1200
            KALIERPSQNNIGIQTMECSLRVPETVSAATQTIKNVCEQGTSTVDQNFGKQDATVQTER
Sbjct: 1146 KALIERPSQNNIGIQTMECSLRVPETVSAATQTIKNVCEQGTSTVDQNFGKQDATVQTER 1205

Query: 1201 GSGEKPVSAPGDDTESLHSQGEEEFDMPQPPHGHVLHRHMRTIREVRTLVTRVITDVYYV 1260
            GSGEKPVSAPGDDTESLHSQGEEEFDMPQPPHGHVLHRHMRTIREVRTLVTRVITDVYYV
Sbjct: 1206 GSGEKPVSAPGDDTESLHSQGEEEFDMPQPPHGHVLHRHMRTIREVRTLVTRVITDVYYV 1265

Query: 1261 DGTEVERKVTEETEEPIVECQECETEVSPSQTGGSSGDLGDISSFSSKASSLHRTSSGTS 1320
            DGTEVERKVTEETEEPIVECQECETEVSPSQTGGSSGDLGDISSFSSKASSLHRTSSGTS
Sbjct: 1266 DGTEVERKVTEETEEPIVECQECETEVSPSQTGGSSGDLGDISSFSSKASSLHRTSSGTS 1325

Query: 1321 LSAMHSSGSSGKGAGPLRGKTSGTEPADFALPSSRGGPGKLSPRKGVSQTGTPVCEEDGD 1380
            LSAMHSSGSSGKGAGPLRGKTSGTEPADFALPSSRGGPGKLSPRKGVSQTGTPVCEEDGD
Sbjct: 1326 LSAMHSSGSSGKGAGPLRGKTSGTEPADFALPSSRGGPGKLSPRKGVSQTGTPVCEEDGD 1385

Query: 1381 AGLGIRQGGKAPVTPRGRGRRGRPPSRTTGTRETAVPGPLGIEDISPNLSPDDKSFSRVV 1440
            AGLGIRQGGKAPVTPRGRGRRGRPPSRTTGTRETAVPGPLGIEDISPNLSPDDKSFSRVV
Sbjct: 1386 AGLGIRQGGKAPVTPRGRGRRGRPPSRTTGTRETAVPGPLGIEDISPNLSPDDKSFSRVV 1445

Query: 1441 PRVPDSTRRTDVGAGALRRSDSPEIPFQAAAGPSDGLDASSPGNSFVGLRVVAKWSSNGY 1500
            PRVPDSTRRTDVGAGALRRSDSPEIPFQAAAGPSDGLDASSPGNSFVGLRVVAKWSSNGY
Sbjct: 1446 PRVPDSTRRTDVGAGALRRSDSPEIPFQAAAGPSDGLDASSPGNSFVGLRVVAKWSSNGY 1505

Query: 1501 FYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSAGVVKG 1560
            FYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSAGVVKG
Sbjct: 1506 FYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSAGVVKG 1565

Query: 1561 HRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLGPYEAVTPLTKAADISLD 1620
            HRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLGPYEAVTPLTKAADISLD
Sbjct: 1566 HRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLGPYEAVTPLTKAADISLD 1625

Query: 1621 NLVEGKRKRRSNVSSPATPTASSSSSTTPTRKITESPRASMGVLSGKRKLITSEEERSPA 1680
            NLVEGKRKRRSNVSSPATPTASSSSSTTPTRKITESPRASMGVLSGKRKLITSEEERSPA
Sbjct: 1626 NLVEGKRKRRSNVSSPATPTASSSSSTTPTRKITESPRASMGVLSGKRKLITSEEERSPA 1685

Query: 1681 KRGRKSATVKPGAVGAGEFVSPCESGDNTGEPSALEEQRGPLPLNKTLFLGYAFLLTMAT 1740
            KRGRKSATVKP  VGAGEFVSPCESGDNTGEPSALEEQRGPLPLNKTLFLGYAFLLTMAT
Sbjct: 1686 KRGRKSATVKP--VGAGEFVSPCESGDNTGEPSALEEQRGPLPLNKTLFLGYAFLLTMAT 1743

Query: 1741 TSDKLASRSKLPDGPTGSSEEEEEFLEIPPFNKQYTESQLRAGAGYILEDFNEAQCNTAY 1800
            TSDKLASRSKLPDGPTGSSEEEEEFLEIPPFNKQYTESQLRAGAGYILEDFNEAQCNTAY
Sbjct: 1744 TSDKLASRSKLPDGPTGSSEEEEEFLEIPPFNKQYTESQLRAGAGYILEDFNEAQCNTAY 1803

Query: 1801 QCLLIADQHCRTRKYFLCLASGIPCVSHVWVHDSCHANQLQNYRNYLLPAGYSLEEQRIL 1860
            QCLLIADQHCRTRKYFLCLASGIPCVSHVWVHDSCHANQLQNYRNYLLPAGYSLEEQRIL
Sbjct: 1804 QCLLIADQHCRTRKYFLCLASGIPCVSHVWVHDSCHANQLQNYRNYLLPAGYSLEEQRIL 1863

Query: 1861 DWQPRENPFQNLKVLLVSDQQQNFLELWSEILMTGGAASVKQHHSSAHNKDIALGVFDVV 1920
            DWQPRENPFQNLKVLLVSDQQQNFLELWSEILMTGGAASVKQHHSSAHNKDIALGVFDVV
Sbjct: 1864 DWQPRENPFQNLKVLLVSDQQQNFLELWSEILMTGGAASVKQHHSSAHNKDIALGVFDVV 1923

Query: 1921 VTDPSCPASVLKCAEALQLPVVSQEWVIQCLIVGERIGFKQHPKYKHDYVSH 1972
            VTDPSCPASVLKCAEALQLPVVSQEWVIQCLIVGERIGFKQHPKYKHDYVSH
Sbjct: 1924 VTDPSCPASVLKCAEALQLPVVSQEWVIQCLIVGERIGFKQHPKYKHDYVSH 1975


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 151/837 (18%), Positives = 288/837 (34%), Gaps = 56/837 (6%)

Query: 60   DVVSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPNRTSS 119
            D  S  +    +  G+GN+G +++ K +      DSS+ D+  S +         + + S
Sbjct: 514  DSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSN-------SSDSSDS 566

Query: 120  VLGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQSQ 179
                S +S  + + +  +       + +   S N++ S  + D++ S       + S S 
Sbjct: 567  SDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSS------DSSDSS 620

Query: 180  DVEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPVT 239
            D + ++   E D     S  ++S  +  SD   N+       S+     ++ S      +
Sbjct: 621  DSKSDSSKSESDSSDSDS-KSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSS 679

Query: 240  AQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSPEPEV 299
            +  S +     + +     SE    S  +   + ++ +  ++            S +   
Sbjct: 680  SSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSN 739

Query: 300  LSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSL-STN 358
             S   D  D SN + SSD   + +  +   S  S+ ++       S   S   DS  S+N
Sbjct: 740  SSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSN 799

Query: 359  SSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELE 418
            SSD    S  +  S      SS +          D+S  S+            G   +  
Sbjct: 800  SSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSD---SSDSSDGSDSDSS 856

Query: 419  NPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGKKDG 478
            N      S+ S  +S   + S       S    ++   S D    S S +  S+D     
Sbjct: 857  NRSDSSNSSDSSDSSDSSNSSDSSDSSDS----NESSNSSDSSDSSNSSDSDSSDSSNSS 912

Query: 479  DMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHRIDE 538
            D   SS + + S++S     ++  D   S + DS      +S+ S S    + S      
Sbjct: 913  DSSDSSNSSDSSESSNSSDNSNSSD--SSNSSDSS----DSSDSSNSSDSSNSSDSSNSS 966

Query: 539  DGENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDIS 598
            D  ++   D+   S   NS      +DS   + + D     S + D +   D+    D S
Sbjct: 967  DSSDSNSSDSSDSS---NSSDSSDSSDSSDSSDSSDSS-NSSDSSDSSDSSDSSNSSDSS 1022

Query: 599  ILATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEG 658
              +      + + + D     + DS   +  S ++ S   S   D  ++ +  +    + 
Sbjct: 1023 NSSDSSNSSDSSDSSD-----SSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD--SSDS 1075

Query: 659  SSGSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSEAMEV 718
            S  S+  E  ++   S   +  + +  S     S +   S            + S++ + 
Sbjct: 1076 SDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1135

Query: 719  ETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPLEGV 778
              S  S DS       D        ++ + + S DSS    D  + S   D S       
Sbjct: 1136 SDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSS----DSSDSSNSSDSS------- 1184

Query: 779  EKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSLPLV 838
               SDS    D +   +  + +  D+ +        D    +  ++  + + S  S    
Sbjct: 1185 -DSSDSSDSSDSSDSSD--SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSS 1241

Query: 839  RADDPLRLDQELQQPQTQEKTSNSLTE---DSKMANAKQLSSDAEAQKLGKPSAHAS 892
             + D            + + TS+S  E    SK  N     SD+++   G  S H++
Sbjct: 1242 DSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHST 1298



 Score = 64.7 bits (156), Expect = 9e-10
 Identities = 148/854 (17%), Positives = 284/854 (33%), Gaps = 41/854 (4%)

Query: 63   SNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPNRTSSVLG 122
            S+  +   +E G GN G  +  +   +   +   N+ T G +   IE   Q +   + +G
Sbjct: 382  SSGNRNITKEVGKGNEGKEDKGQHGMI---LGKGNVKTQGEVVN-IEGPGQKSEPGNKVG 437

Query: 123  MSVESAPAVEE-----EKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQ 177
             S   + +  +     +  ++  Q +     D S     +    D  SS  G       +
Sbjct: 438  HSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDE 497

Query: 178  SQDVEE--NTVPYEVDKEQLQSVTTNS-----GYTRLSDVDANTAIKHEEQSNEDIPIAE 230
            S+D     ++   E D     S T NS     G     D D + + K +  S++      
Sbjct: 498  SKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDS 557

Query: 231  QSSKDIPVTAQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQ 290
             +S D    +  S D       +   + S D   S  +   + ++     + +  +S   
Sbjct: 558  SNSSD----SSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDS 613

Query: 291  IQKSPEPEVLS----TQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSG 346
               S   +  S    ++ D  D  +K+ SSD  S+ S +    S +S  + +      S 
Sbjct: 614  SDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSD 673

Query: 347  QRSLVQDSLSTNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQ 406
                   S S+NSSD    S D+  S+     S  ++           S  S        
Sbjct: 674  SSDSSSSSDSSNSSD----SSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSS 729

Query: 407  KKLQSGEPVELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPS 466
                S +     +     +S+ S  +S     S       S         S+       S
Sbjct: 730  NSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSS 789

Query: 467  LEEQSNDGKKDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSP 526
                S+D     D  +SS + + S +S+ +  NS +    S + DS     S+     S 
Sbjct: 790  NSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSD 849

Query: 527  KMESLSSHRIDEDGENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKT 586
              +S SS+R D    +    D+   S   NS      +DS   + + D     S + D  
Sbjct: 850  GSDSDSSNRSDSSNSS----DSSDSSDSSNSSDSSDSSDSNESSNSSDSS-DSSNSSDSD 904

Query: 587  KGDDTDTRDDISILATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEE 646
              D +++ D      +         +++     + +S   +  S ++ S   S+  D   
Sbjct: 905  SSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSN 964

Query: 647  AMEIKEHHPEEGSSGSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKE 706
            + +  + +  + S  S   +  ++   S   +  + +  S     S +   S        
Sbjct: 965  SSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNS 1024

Query: 707  MPKKECSEAMEVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSP 766
                  S++ +   S  S DS       D        ++ + + S DSS    D  + S 
Sbjct: 1025 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS----DSSDSSD 1080

Query: 767  RVDVSCEPLEGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPV 826
                S E  +  +  + S S +         + +  D+ +        D    +  ++  
Sbjct: 1081 ----SSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1136

Query: 827  EQDSSQPSLPLVRADDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGK 886
            +  +S  S     + D            + + + +S + DS  ++    SSD+       
Sbjct: 1137 DSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 1196

Query: 887  PSAHASQSFCESSS 900
             S+ +S S   S S
Sbjct: 1197 DSSDSSDSSDSSDS 1210



 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 114/671 (16%), Positives = 218/671 (32%), Gaps = 6/671 (0%)

Query: 9    DSDFSQQDTPCLIIEDSQPESQVLEDDSGSHFSMLSRHLPNLQTHKENPVLDVVSNPEQT 68
            DS  S   +      DS+ +S   E DS    S       N     +N      SN   +
Sbjct: 606  DSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNS 665

Query: 69   AGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPNRTSSVLGMSVES- 127
            +       +S  +     +  +D  DSS+       S   +     +  SS    S  S 
Sbjct: 666  SDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSD 725

Query: 128  APAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQSQDVEENTVP 187
            + +       +        +   S N++ S  + D+++S       + S S D   ++  
Sbjct: 726  SDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDS 785

Query: 188  YEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTAQPSKDVH 247
             +       S ++NS  +  S   ++++   +  S+     +  S       +  S D  
Sbjct: 786  NDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSS 845

Query: 248  VVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSPEPEVL-STQEDL 306
               + +   + +     +   S  + ++     + +  +S      S   +   S+  D 
Sbjct: 846  DSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDS 905

Query: 307  FDQSNKTVSSDGC-STPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSLSTNSSDLVAP 365
             D SN + SSD   S+ S E    S  S  + + +    S        S S+NSSD    
Sbjct: 906  SDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNS 965

Query: 366  SPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELENPPLLPE 425
            S  +  ++     SS +          D+S  S+           S +  +  N      
Sbjct: 966  SDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNS--SDSSDSSDSSDSSNSSDSSN 1023

Query: 426  STVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGKKDGDMHSSSL 485
            S+ S  +S     S       S         S+       S    S+D     D   SS 
Sbjct: 1024 SSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSE 1083

Query: 486  TVECSKTS-EIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHRIDEDGENTQ 544
            + + S +S   +  +S +    S + DS     S+   + S   +S  S    +   ++ 
Sbjct: 1084 SSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSD 1143

Query: 545  IEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDISILATGC 604
              D+   S   +S      +DS   + + D     + +D     D +D+ D      +  
Sbjct: 1144 SSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1203

Query: 605  KGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEV 664
                   ++      + DS   +  S +  S   S   D  ++    +      SS S  
Sbjct: 1204 SSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTS 1263

Query: 665  EEIPETPCESQ 675
            +   E+  +S+
Sbjct: 1264 DSNDESDSQSK 1274



 Score = 50.4 bits (119), Expect = 2e-05
 Identities = 105/597 (17%), Positives = 198/597 (33%), Gaps = 38/597 (6%)

Query: 2    DPTGSQLDSDFSQQDTPCLIIEDSQPESQVLEDDSGSHFSMLSRHLPNLQTHKENPVLDV 61
            D + S   S+ +  D+      DS   S   +    S  S  S    +  +   +   D 
Sbjct: 711  DSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDS 770

Query: 62   VSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPNRTSSVL 121
              + + +      D N   N        +D  DSSN     + S   +     +  SS  
Sbjct: 771  SDSSDSSDSSNSSDSNDSSNS-------SDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNS 823

Query: 122  GMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQSQDV 181
              S  S+ + +     +      +  + + G+ + S    D+++S       + S S D 
Sbjct: 824  SDSSNSSDSSDSSNSSD----SSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDS 879

Query: 182  EENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTAQ 241
             +++   E       S ++NS  +  SD  +N++   +  ++ D   +  SS        
Sbjct: 880  SDSSDSNESSNSSDSSDSSNSSDSDSSD-SSNSSDSSDSSNSSDSSESSNSS-------- 930

Query: 242  PSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSPEPEVLS 301
                       N   + S +   S  +S ++  +    S+     S      S +    S
Sbjct: 931  ----------DNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSS 980

Query: 302  TQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSLSTNSSD 361
               D  D S+ + SSD   + +  +   S  S+ ++       S   S   DS  ++ S 
Sbjct: 981  NSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSS 1040

Query: 362  LVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELENPP 421
              + S D+  S+     S  ++     D   D+S  S+          +S +  +  N  
Sbjct: 1041 DSSDSSDSSDSSDSSNSSDSSDSSDSSDSS-DSSDSSDSSDSS-----ESSDSSDSSNSS 1094

Query: 422  LLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGKKDGDMH 481
               +S+ S  +S     S       S         S        S    S+D  +  D  
Sbjct: 1095 DSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSS 1154

Query: 482  SSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHRIDEDGE 541
             SS + + S +S+    +   D   S + DS     S+     S   +S  S    +  +
Sbjct: 1155 DSSDSSDSSDSSDSSDSSDSSDS--SNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1212

Query: 542  NTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDIS 598
            ++   D+   S   +S      +DS   + + D       +D     D T   +D S
Sbjct: 1213 SSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDES 1269



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 68/432 (15%), Positives = 145/432 (33%), Gaps = 10/432 (2%)

Query: 472 NDGKKDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESL 531
           ND    G   S S   + S +S     +   D   S +  S     S S+ S S   +S 
Sbjct: 537 NDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSS 596

Query: 532 SSHRIDEDGENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDT 591
            S    +  +++   D+   S   +SK   ++++S     + D + + S + D    D +
Sbjct: 597 DSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSES----DSSDSDSK-SDSSDSNSSDSS 651

Query: 592 DTRDDISILATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIK 651
           D  D      +         ++      + DS + +  S ++ S   S   D  ++ +  
Sbjct: 652 DNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSD 711

Query: 652 EHHPEEGSSGSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMP-KK 710
                + S+ +  +       +S       ++ +S     S   + S       +     
Sbjct: 712 SSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSS 771

Query: 711 ECSEAMEVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDV 770
           + S++ +   S  S DS       D         + + + S DSS    D    +     
Sbjct: 772 DSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSS----DSDSSNSSDSS 827

Query: 771 SCEPLEGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDS 830
           +          SDS    D +   +  + NR D+          D  + +  ++  + + 
Sbjct: 828 NSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNE 887

Query: 831 SQPSLPLVRADDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAH 890
           S  S     + +    D       +    S++ ++ S+ +N+   S+ +++      S  
Sbjct: 888 SSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDS 947

Query: 891 ASQSFCESSSET 902
           +  S    SS +
Sbjct: 948 SDSSNSSDSSNS 959


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 71.2 bits (173), Expect = 9e-12
 Identities = 285/1408 (20%), Positives = 465/1408 (33%), Gaps = 221/1408 (15%)

Query: 142  KEKEKEEDTSGNTT-HSLGAEDTASSQLGFGVLELSQSQDVEENTVPYEVDKEQLQSVTT 200
            + +   E TS +TT      EDT+S     G        DV  +T   E     +  V+T
Sbjct: 114  ESRTTSESTSDSTTLFPSSTEDTSSPTTPEGT-------DVPMSTPSEESISSTMAFVST 166

Query: 201  N-----SGYTRLS-DVDANTAIKHEEQSNED--------IPIAEQSSKDIPVTAQPSKDV 246
                    YT L+  VD +T +    Q++          IP +  S    P+T+ P+  +
Sbjct: 167  APLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGSTPLTSMPASTM 226

Query: 247  HVVKEQ-----NPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESG----------LQI 291
             V   +       P   S  +  S +AS +   A+    +      G          + +
Sbjct: 227  KVASSEAITLLTTPVEISTPVTISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVML 286

Query: 292  QKSPEPEVLSTQEDLF--------DQSNKTVSSDGCSTPSRE--EGGCSLASTPATTLHL 341
              S E   LST             + S+   +++G S P+    EG   L STPA+T+ +
Sbjct: 287  VVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPV 346

Query: 342  LQLS-GQRSLVQDSLSTNSSDLVAPS--PDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLS 398
                    S+     ST  +    PS  P    +T  +  +         + P+ T +++
Sbjct: 347  ATSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVA 406

Query: 399  EEGGE-----PFQKKLQSGEPVELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQ 453
                      P   K       E  + P   E T S   STP   STP+    S+P+ + 
Sbjct: 407  SSEASTTSTIPVDSKTFVTTASEASSSPTTAEDT-SIATSTPSEGSTPL---TSMPVSTT 462

Query: 454  PQFSHDIFIPSPSLEEQSNDGKKDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSC 513
            P  S +    S +  +         +  SS  T E +      P ++P +    LT  S 
Sbjct: 463  PVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSM----PTSTPSEGSTPLTSMSV 518

Query: 514  KLM-LSTSEYS---------QSPKMESLSSHRIDEDGENTQIEDTEPMS--------PVL 555
              M +++SE S          +P   S  +       E T I  + P          PV 
Sbjct: 519  STMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVS 578

Query: 556  NSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDISILATGCKGREETVAEDV 615
                V +E  +    PA       + ++       + T  + + + T       T    +
Sbjct: 579  TRLVVSSEASTTSTTPADSNTFVTTSSE----ASSSSTTAEGTSMPTSTYSERGTTITSM 634

Query: 616  CIDLTCDSGSQAVP---------SPATRSEALSSVLDQEEAMEIKEHHPEEGS------- 659
             +  T  + S+A           +P T S   +S     E   +      EGS       
Sbjct: 635  SVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMP 694

Query: 660  ------SGSEVEEIPETPCESQGEELKEENMESVPLHLS----LTETQSQGLCLQKEMPK 709
                  + SE   +  TP ++           S P         T T S+G      MP 
Sbjct: 695  VNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPV 754

Query: 710  KE----CSEAMEVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPS 765
             +     SEA  + T+ +   +          +    + +    T+E +S+ I    E S
Sbjct: 755  SKTLLTSSEASTLSTTPLDTST---------HITTSTEASCSPTTTEGTSMPISTPSEGS 805

Query: 766  P---RVDVSCEPLEGVEKCS------DSQSWEDIAPEIEPCAENRLDTKEEKSVEYEG-- 814
            P    + VS  P+   E  +      DS S    + E+         T    S   EG  
Sbjct: 806  PLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRT 865

Query: 815  DLKSGTAETEPVEQD--SSQPSLPLVRADDPLRLDQELQQPQTQEKTS-------NSLTE 865
             L S    T  V     S+  + P+  +       +    P T E TS          T 
Sbjct: 866  PLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTP 925

Query: 866  DSKMANAKQLSSDAEAQKLGKPSAHASQSFCESSSETPFHFTLPKEGDIIP---PLTGAT 922
             + M ++      +EA+ L       S     S+  T    T   EG  IP   P  G T
Sbjct: 926  LTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTT--AEGTSIPTSTPSEGTT 983

Query: 923  PPLIGHLKLEPKRHSTPIGISNYPESTIATSDVMSESMVET-----HDPILGSGKGDSGA 977
            P     L   P  H+    ++N   ST++T+ V S + + T       P    G     +
Sbjct: 984  P-----LTSTPVSHTL---VANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTS 1035

Query: 978  APDVDDKLCLRMKLVSPETEASEES----LQFNLEKPATG-ERKNGSTAVAESVASPQKT 1032
             P        RM + +    +SE S       +   P T   + + S+  A+  + P  T
Sbjct: 1036 TPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTST 1095

Query: 1033 MS-----VLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKEKLEGDHTIRQSQ 1087
             S     + S     R    + +    TTP+  ++    S++        EG  T   + 
Sbjct: 1096 YSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEG--TSIPTS 1153

Query: 1088 QPMKPISPVKD-------------------PVSPASQKMVIQGPSSPQGEAMVTDVLEDQ 1128
             P +  +P+                     PV   +Q       SSP   A VT +    
Sbjct: 1154 PPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTST 1213

Query: 1129 KEGRSTNKENPSKALIERPSQNNIGIQTMECSLRVPETVSAATQTIKNVCEQGTSTVDQN 1188
               RST   +         S     + T       P T SA T +     E GTS +  +
Sbjct: 1214 PGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAE-GTS-LPTS 1271

Query: 1189 FGKQDATVQTERGSGEKPVSAPGD--------DTESLHSQGEEEFDMPQPPHGHVLHRHM 1240
               + +T+ T        V++P          DT+       E    P P  G  +    
Sbjct: 1272 TTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSM--PT 1329

Query: 1241 RTIREVRTLVTRVITDVYYVDGTEVERKVTEETEEPIVECQECETEVSPSQTGGSSGDLG 1300
             T  E RT +T +  +   V  + +    T   +         E   SP+ + G+S    
Sbjct: 1330 STYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTS---- 1385

Query: 1301 DISSFSSKASSLHRTSSGTSLSAMHSSGSSGKGAGPLRGKTSGTEPAD----------FA 1350
             + + +    +   TS   S + + SS +S   A P+   T GT  A+           +
Sbjct: 1386 -MPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGIS 1444

Query: 1351 LPSSRGGPGKLSPRKGVSQTGTPVCEED 1378
            +P+S    GK +P K +  + TPV   +
Sbjct: 1445 IPTSTPSEGK-TPLKSIPVSNTPVANSE 1471



 Score = 65.5 bits (158), Expect = 5e-10
 Identities = 260/1256 (20%), Positives = 418/1256 (33%), Gaps = 205/1256 (16%)

Query: 182  EENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTAQ 241
            E ++ P   +   + +   + G T L+ +  +T +    ++N        S   +  + +
Sbjct: 1137 EASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTE 1196

Query: 242  PSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSPEPEVLS 301
             S          PP A    MP S        E    L++  +  + +    S E   LS
Sbjct: 1197 ASSP--------PPTAEVTSMPTSTPG-----ERSTPLTSMPVRHTPVA---SSEASTLS 1240

Query: 302  TQEDLFDQSNK-TVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSLSTNSS 360
            T     D S   T S++  S+P+  EG     S P +T      + + S +  S+  +++
Sbjct: 1241 TSP--VDTSTPVTTSAETSSSPTTAEG----TSLPTST------TSEGSTLLTSIPVSTT 1288

Query: 361  DLVAPSPDAFRSTPFI----------VPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQ 410
             + +P      +TP            V SSPT  EG     M TS  SE G  P      
Sbjct: 1289 LVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTS---MPTSTYSE-GRTPL----- 1339

Query: 411  SGEPVELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQ 470
            +  PV   N  L+  S +S  ++TP+  STPV    S    S P  S    +P       
Sbjct: 1340 TSIPV---NTTLVASSAISILSTTPVDNSTPV--TTSTEACSSPTTSEGTSMP------- 1387

Query: 471  SNDGKKDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTG-DSCKLMLSTSEYSQSPKME 529
             N    +G    +S+ V  +      P  S E   LS T  D+     +++E + SP   
Sbjct: 1388 -NSNPSEGTTPLTSIPVSTT------PVVSSEASTLSATPVDTSTPGTTSAEATSSP--- 1437

Query: 530  SLSSHRIDEDGENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGD 589
                       E   I  + P       K +P  N  +              N + +   
Sbjct: 1438 --------TTAEGISIPTSTPSEGKTPLKSIPVSNTPV-------------ANSEASTLS 1476

Query: 590  DTDTRDDISILATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAME 649
             T    +  ++ +       T AE   I         A+ +P+  S AL+S+      + 
Sbjct: 1477 TTPVDSNSPVVTSTAVSSSPTPAEGTSI---------AISTPSEGSTALTSIPVSTTTV- 1526

Query: 650  IKEHHPEEGSSGSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPK 709
                      + SE+  +  TP  +           S P       T + G  +Q     
Sbjct: 1527 ----------ASSEINSLSTTPAVTSTPVTTYSQASSSP-------TTADGTSMQTSTYS 1569

Query: 710  KECSEAMEVETSVISIDSPQKLAILDQELEHKEQ-----EAWEEATSEDSSVVIVDVKEP 764
            +  +    +  S + + S +   +    ++ K Q     EA    T+E SS+ I    E 
Sbjct: 1570 EGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEG 1629

Query: 765  SP---RVDVSCEPLEGVEKCS------DSQSWEDIAPEIEPCAENRLDTKEEKSVEYEG- 814
            SP    + VS  P+   E  +      DS S    + E+         T    S   EG 
Sbjct: 1630 SPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGR 1689

Query: 815  -DLKSGTAETEPVEQDSSQPSLPLVRADDPLRLDQELQQPQTQEKTSNSLTEDSKMANAK 873
              L S T  T PV   S+  +L     D+   +        T+ ++S + +E + M N+ 
Sbjct: 1690 TPLTSITVRTTPV-ASSAISTLSTTPVDNSTPV-----TTSTEARSSPTTSEGTSMPNST 1743

Query: 874  QLSSDAEAQKLGKPSAHASQSFCESSSETPFHFTLP-------------KEGDIIPPLT- 919
                      +   +     S   + S TP   + P              EG  IP  T 
Sbjct: 1744 PSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTL 1803

Query: 920  --GATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDVMSESMVETHDPILGS---GKGD 974
              G TP     L   P  H+    ++N   ST++T+ V S S V T   +  S    +G 
Sbjct: 1804 SEGMTP-----LTSTPVSHTL---VANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGT 1855

Query: 975  S-GAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGERKNGSTAVAESVASPQKTM 1033
            S   +   +    L    VS  T AS E+   +     T         V+ S  +   + 
Sbjct: 1856 SIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSS 1915

Query: 1034 SVLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKEKLEGDHT--IRQSQQPMK 1091
               S   E R         PP T I  +     SS+       L    T     SQ    
Sbjct: 1916 MPTSTPREGR---------PPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQASSS 1966

Query: 1092 PISPVKDPV-SPASQKMVIQGPSSPQGEAMVTDVLEDQKEGRSTNKENPSKALIERPSQ- 1149
            P +     + +PA  +      S P    +V             +   P+    E  S  
Sbjct: 1967 PTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSP 2026

Query: 1150 ---NNIGIQTMECSLRVPETVSAATQTIKNVCEQG----TSTVDQNFGKQDATVQTERGS 1202
                   IQT   S R          T   V  +G    T+ VD      ++T  +   +
Sbjct: 2027 TTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSAT 2086

Query: 1203 GE---KPVSAPGDDTESLHSQGEEEFDMPQPPHGHVLHRHMRTIREVRTLVTRVITDVYY 1259
             E     +SAP + +  L S       +  P    +    + +   V T  T V +    
Sbjct: 2087 AEGSSMTISAPSEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVIT-STEVSSSPIP 2145

Query: 1260 VDGTEVERKVTEETEEPIVECQECETEVSPSQTGGSSGDLGDIS---SFSSKASSLHRTS 1316
             +GT ++     +   P+       T V+ S     S    D S   + S++A S   TS
Sbjct: 2146 TEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTS 2205

Query: 1317 SGTSL-SAMHSSGSSGKGAGPL--------RGKTSGTEPADFALPSSRGGPGKLSP 1363
             GTS+ ++  S GS+   + P+           T    P D + P +       SP
Sbjct: 2206 EGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSP 2261



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 322/1730 (18%), Positives = 547/1730 (31%), Gaps = 185/1730 (10%)

Query: 48   PNLQTHKENPV---LDVVSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSI 104
            P   T    PV     V+++ E ++     +G S       E +   P+ S  + T    
Sbjct: 1646 PEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRT--PLTSITVRTTPVA 1703

Query: 105  SQVIEQL---PQPNRTSSVLGMSVESAPAVEEEKGEELEQKEKEKEEDTS--GNTTHSLG 159
            S  I  L   P  N T         S+P   E          +     TS   +TT  L 
Sbjct: 1704 SSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLS 1763

Query: 160  AEDTASSQLGFGVLELSQ--SQDVEENTVPYEVDKEQLQSVTTNSGYTRLSDVD-ANTAI 216
            +E   +S L    ++ S   +   E  + P   +   + + T + G T L+    ++T +
Sbjct: 1764 SE---ASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLV 1820

Query: 217  KHEEQSNEDIPIAEQSSKDIPVTAQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAK 276
             + E S       + +S  +  TA  S         +P PA    +  S  +  +     
Sbjct: 1821 ANSEASTLSTTPVDSNSPVVTSTAVSS---------SPTPAEGTSIATSTPSEGSTALTS 1871

Query: 277  EQLSAQELMESGLQIQKSPEPEVLSTQEDLFDQ-SNKTVSSDGCSTPSR--EEGGCSLAS 333
              +S   +  S      S  P V ST    + Q S+   ++DG S P+    EG   L S
Sbjct: 1872 IPVSTTTVASSETNTL-STTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTS 1930

Query: 334  TPATTLHLLQLSGQRSLVQDSLSTNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMD 393
             P +T  +   S + + +  +L+   + +   S  +   T     S PT        P+ 
Sbjct: 1931 IPVSTTTVA--SSEINTLSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTPLT 1988

Query: 394  TSVLSEEGGEPFQKKLQSGEPVELENPPLLP-ESTVSP--------QASTPISQSTPV-- 442
            +  LS       +    S  PV+   P     E + SP        Q STP  ++TP+  
Sbjct: 1989 SMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAG 2048

Query: 443  FPPGS-LPIPSQPQFSHDIFIPSPSLEEQSNDGKKDGDMHSSSLTVECSKTSE------- 494
             P  + L + S+        + S +    S +         SS+T+              
Sbjct: 2049 MPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIP 2108

Query: 495  --IEPKNSPEDLGLSLTG-DSCKLMLSTSEYSQSP-KMESLSSHRIDEDGENTQIEDTEP 550
                P  SPE   LS T  DS   +++++E S SP   E  S          T +     
Sbjct: 2109 LSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPV 2168

Query: 551  MSPVLNSKFV------------PAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDIS 598
             + V+ S  +            P  N +   +     E         ++G    T   +S
Sbjct: 2169 STTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVS 2228

Query: 599  ILATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEG 658
             +           A  V       + ++A  SP T            E        P   
Sbjct: 2229 TMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSH 2288

Query: 659  S--SGSEVEEIPETPCESQGEELKEENMESVPLHLS----LTETQSQGLCLQKEMPKKEC 712
            +  + SEV  +  TP +S           S P         T T S+G      MP    
Sbjct: 2289 TLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTT 2348

Query: 713  SEAMEVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSC 772
              A   ETS +S       A     +    Q      T++D+S+      E S    ++ 
Sbjct: 2349 MVA-SFETSTLSTTP----ADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGS--TPLTS 2401

Query: 773  EPLEGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAE------TEPV 826
             P+  +   S   S     P         +DT    +   E      TAE      + P 
Sbjct: 2402 VPVSTMPVVSSEASTHSTTP---------VDTSTPVTTSTEASSSPTTAEGTSIPTSPPS 2452

Query: 827  EQDSSQPSLPLVRADDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGK 886
            E  +   S+P+  +  P+   +      T   TS  +T  ++ +     SS   A+ +  
Sbjct: 2453 EGTTPLASMPV--STTPVVSSEAGTLSTTPVDTSTPMTTSTEAS-----SSPTTAEDIVV 2505

Query: 887  PSAHASQ--SFCESSSETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISN 944
            P + AS+  +   S   +      P+   +      +  P++   ++     +T    ++
Sbjct: 2506 PISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSS--ATSAEGTS 2563

Query: 945  YPESTIATSDVMSESMVETHDPILGSGKGDSGAAP-DVDDKLCLRMKLVSPETEASEESL 1003
             P ST +       SM  +  P+  S        P D    +    +  S  T A + S+
Sbjct: 2564 MPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSM 2623

Query: 1004 QFNLEKPATGERKNGSTAVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNL- 1062
              +     +    +   +     +S   T+S               +   PTT    ++ 
Sbjct: 2624 PISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMP 2683

Query: 1063 LHFPSSQGEEEKEKLEGDHTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVT 1122
               P  +       L     +  S+      +PV       +       P++ +G +M  
Sbjct: 2684 TSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRI 2743

Query: 1123 DVLEDQKEGRSTNKENPSKALIERPSQNNIGIQTMECSLRVPETVS---AATQTIKNVCE 1179
                D     ST   +   + +   S     + T      +P T S   +++ T   V  
Sbjct: 2744 STPSDG----STPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTS 2799

Query: 1180 QGTSTVDQNFGKQDATVQTERGSGEKPV--------SAPGDDTESLHSQGEEEFDMPQPP 1231
              TST  +      +T  T       PV        S    DT +  +   +    P   
Sbjct: 2800 MPTSTPSET-----STPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTA 2854

Query: 1232 HGHVLHRHMRTIREVRTLVTRVITDVYYVDGTEVERKVTEETEEPIVECQECETEVSPSQ 1291
             G V+   + T  E  TL+T +      V  +E     T   +  I      E   SP+ 
Sbjct: 2855 EGIVVP--ISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTT 2912

Query: 1292 TGGSSGDLGDISSFSSKASSLHRTS---SGTSLSAMHSSGSSGKG--AGPLRGKTSGTEP 1346
              G+S  +   S  S+  +S+  ++   +G+  S + ++    +          +S T  
Sbjct: 2913 AEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTA 2972

Query: 1347 ADFALPSSRGGPGKLSPRKGVSQTGTPVCEEDGDAGLGIRQGGKAPVTPRGRGRRGRPPS 1406
               ++P S  G  + +P   +S +  PV   +             PVT           S
Sbjct: 2973 EGTSMPISTPGE-RRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEA-----SS 3026

Query: 1407 RTTGTRETAVPGPLGIEDISPNLSPDDKSFSRVVPRVPD-STRRTDVGAGALRRSDSPEI 1465
              T    T +P     E  +P  S    +    +P     ST   D        S+SP +
Sbjct: 3027 SPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVD--------SNSPVV 3078

Query: 1466 -PFQAAAGPSDGLDASSPGNSFVGLRVVAKWSSNGYFYSGKITRDVGAGKYKLLFDDGYE 1524
               + ++ P+     S P +++                          G   L       
Sbjct: 3079 TSTEVSSSPTPAEGTSMPISTY------------------------SEGSTPLTGVPVST 3114

Query: 1525 CDVLGKDILLCDPIPLDTEVTALSEDEYFSAGVVKGHRKESGELYYSIEKEGQRK-WYKR 1583
              V    I      P+DT     +  E  S+        E   +  S   EG     Y  
Sbjct: 3115 TPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTT----SEGTSMPTSTPSEGSTPLTYMP 3170

Query: 1584 MAVILSLEQGNRLREQYGLGPYEAVTPLTKAADISLDNLVEGKRKRRSNVSSPATPTASS 1643
            ++ +L +   +         P +  TP+T + + +     EG     S  S   TP  S 
Sbjct: 3171 VSTMLVVSSED---STLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSV 3227

Query: 1644 SSSTTPTRKITESPRASMGVLSGKRKLITSEEERS--PAKRGRKSATVKP 1691
              S TP    +E+   S   +     L TS E  S  P   G    T  P
Sbjct: 3228 PVSNTPVAS-SEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTP 3276



 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 226/1130 (20%), Positives = 371/1130 (32%), Gaps = 130/1130 (11%)

Query: 92   PVDSSNLDTCGSISQVIEQLPQPNRTSSVLG--MSVESAPAVEEEKGEELEQKEKEKEED 149
            PVD+S L T    S     LP     +S+L   +S  S P         L    +     
Sbjct: 358  PVDTSTLVTT---STEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTS 414

Query: 150  TS--GNTTHSLGAEDTASSQLGFGVLELSQSQDVEENTVPYEVDKEQLQSVTTNSGYTRL 207
            T    + T    A + +SS        ++ S   E +T    +        ++ +     
Sbjct: 415  TIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLST 474

Query: 208  SDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTAQPSKDVHVVKEQNPPPARSEDMPFS-- 265
            + VD+ T +    +++   P AE +S      ++ S  +  +     P A SE    S  
Sbjct: 475  TPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTT 534

Query: 266  PKASVAAMEAKEQLSAQELMESGLQIQKSPEPEVLSTQEDLFDQSNKTVSSDGCSTPSRE 325
            P  +   +    + S+      G  I  S   E  +   ++   +   VSS+  +T +  
Sbjct: 535  PVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTP 594

Query: 326  EGG------CSLASTPATTLHLLQLS----GQRSLVQDSLSTNSSDLVAPSPDAFRSTPF 375
                      S AS+ +TT     +      +R     S+S  S+ LVA S  +  ST  
Sbjct: 595  ADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSV-STTLVASSEASTLSTTP 653

Query: 376  IVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELE--NPPLLPESTVSPQAS 433
            +  ++P        +   +S  +E    P     +   P+     N  L+  S  S  ++
Sbjct: 654  VDSNTPVTTS---TEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLST 710

Query: 434  TPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGKKDGDMHSSSLTVECSKTS 493
            TP+  STPV    S    S P  +    +P+ +  E S        M  S   +  S+ S
Sbjct: 711  TPVDTSTPV--TTSTEASSSPTTADGASMPTSTPSEGSTPLT---SMPVSKTLLTSSEAS 765

Query: 494  EIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHRIDEDGENTQIEDTEPMS- 552
             +    +P D    +T        +++E S SP     +S  I    E + +  + P+S 
Sbjct: 766  TL--STTPLDTSTHIT--------TSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSI 815

Query: 553  -PVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDISILATGCKGREETV 611
             PV + +        +  N       ++S +    +G    T       +T  +GR    
Sbjct: 816  TPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPT-------STYSEGRTPLT 868

Query: 612  AEDVCIDLTCDSGSQAV-------PSPATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEV 664
            +  V   L   S    +        +P T S    S     E   +    P EGS+    
Sbjct: 869  SMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTS 928

Query: 665  EEIPETP-CESQGEELKEENME-SVPLHLSLTETQSQGLCLQKEMPKKECSEAMEVETSV 722
                 TP   S+   L    ++ S P+  S   T S        +P    SE        
Sbjct: 929  MPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEG------- 981

Query: 723  ISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPLEGVEKCS 782
                +P     +   L    + +    T  DS+  +    E S     +    EG    +
Sbjct: 982  ---TTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTA----EGTSMPT 1034

Query: 783  DSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSLPLVRADD 842
             + S E   P         +    E S      L +  A+T       SQ S     AD 
Sbjct: 1035 STPS-EGSTPLTRMPVSTTMVASSETST-----LSTTPADTSTPVTTYSQASSSSTTADG 1088

Query: 843  ---PLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSFCESS 899
               P     E   P T    S  L   S+ +       D          A +S +  E +
Sbjct: 1089 TSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGT 1148

Query: 900  SETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDVMSES 959
            S       +P      PP  G TP       L     ST + +S+   +T++T+ V S++
Sbjct: 1149 S-------IPTS----PPSEGTTP-------LASMPVSTTLVVSS-EANTLSTTPVDSKT 1189

Query: 960  MVETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGERKNGS 1019
             V T          ++ + P   +   +      P +   E S       P T       
Sbjct: 1190 QVAT--------STEASSPPPTAEVTSM------PTSTPGERS------TPLTSMPVR-H 1228

Query: 1020 TAVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKEKLEG 1079
            T VA S AS   T+S             A +   PTT    +L    +S+G      +  
Sbjct: 1229 TPVASSEAS---TLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPV 1285

Query: 1080 DHTIRQSQQPMKPISPVKDPVSP-ASQKMVIQGPSSPQGEAMVTDVLEDQKEGRSTNKEN 1138
              T+  S +    ++   D   P  +   V   P+  +G +M T       EGR+     
Sbjct: 1286 STTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTST---YSEGRTPLTSI 1342

Query: 1139 PSKALIERPSQNNIGIQTMECSLRVPETVSAATQTIKNVCEQGTSTVDQN 1188
            P    +   S  +I + T       P T S    +     E GTS  + N
Sbjct: 1343 PVNTTLVASSAISI-LSTTPVDNSTPVTTSTEACSSPTTSE-GTSMPNSN 1390



 Score = 41.6 bits (96), Expect = 0.008
 Identities = 96/479 (20%), Positives = 173/479 (36%), Gaps = 51/479 (10%)

Query: 149  DTSGNTTHSLGAEDTASSQLGFGVLELSQSQDVEENTVPYEVDKEQLQSVTTNSGYT-RL 207
            DTS   T S  A  + ++  G  +   S S    E T P          V ++   T   
Sbjct: 3366 DTSTPVTTSTEASLSPTTAEGTSIPTSSPS----EGTTPLASMPVSTTPVVSSEVNTLST 3421

Query: 208  SDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTAQPSKDVHVVKEQNPPPARSEDMPFSPK 267
            + VD+NT +    +++    IAE +S     T++ S  + ++     P A SE    +  
Sbjct: 3422 TPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSE----AST 3477

Query: 268  ASVAAMEAKEQLSAQELMESGLQIQKSPEPEVLSTQEDLFDQSNKTVSSDGCSTPSREEG 327
             S   ++    ++      S     +       +  E     +N  VS    +TP     
Sbjct: 3478 LSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVS----TTPVASSE 3533

Query: 328  GCSLASTPATTLHLLQLSGQRSLVQDSLSTNSSDLVAPSPDAFRSTPFIV---------P 378
              +L++TP  +   +  S Q S    +L   +  +  PS  +   T  ++          
Sbjct: 3534 ASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEA 3593

Query: 379  SSPTEQEGRQDKPMDTSVLSEEGGEPFQK-KLQSGEPVELENP-PLLPESTVS------- 429
            S+P+     +  P+ TS  S     P +   L    P E+  P  ++P ST S       
Sbjct: 3594 STPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAG 3653

Query: 430  PQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGKKDGDMHSSSLTVEC 489
              ++ P+  STPV    S  + S P       +P  +  E S        M  S+  V  
Sbjct: 3654 TASTLPVDTSTPVIT--STQVSSSPVTPEGTTMPIWTPSEGSTPLT---TMPVSTTRVTS 3708

Query: 490  SKTSEIEP----KNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHRIDEDGENTQI 545
            S+ S +       ++P          S  L  +T   S   ++ +L +         T +
Sbjct: 3709 SEGSTLSTPSVVTSTPVTTSTEAISSSATLDSTTMSVSMPMEISTLGT---------TIL 3759

Query: 546  EDTEPMS--PVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDISILAT 602
              T P++  P  ++  +P+   S+ M  A +G    +  +  T    + T +  ++L T
Sbjct: 3760 VSTTPVTRFPESSTPSIPSVYTSMSMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTT 3818



 Score = 34.7 bits (78), Expect = 0.95
 Identities = 99/481 (20%), Positives = 167/481 (34%), Gaps = 82/481 (17%)

Query: 52   THKENPVLDVVSNPEQTAGEERGDGNSGF-NEHLKENKVAD---------PVDSSNLDTC 101
            T+      +V S P  TAGE    G++   N  +    VA          PVDS+   T 
Sbjct: 3495 TNSSPTTAEVTSMPTSTAGE----GSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTS 3550

Query: 102  GS--------ISQVIEQLPQPNRTSSVLGMSVESAPAVEEEKGEELEQKEKEKEEDTSGN 153
             S        +     ++  P+  SS L   + S+  V   +             D S  
Sbjct: 3551 SSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEAST----PSTPSVDRSTP 3606

Query: 154  TTHSLGAEDTASSQLGFGVLELSQSQDVEENTVPYEVDKEQLQSVT-TNSGYTRLSDVDA 212
             T S  +  T +      V+ L  S   E +T P  +      SVT + +G      VD 
Sbjct: 3607 VTTSTQSNSTPTPP---EVITLPMSTPSEVST-PLTIMPVSTTSVTISEAGTASTLPVDT 3662

Query: 213  NTAIKHEEQSNED--------IPIAEQSSKDIPVTAQPSKDVHVVKEQN----------- 253
            +T +    Q +          +PI   S    P+T  P     V   +            
Sbjct: 3663 STPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTS 3722

Query: 254  -PPPARSEDMPFSPKASVAAMEAKEQLSAQEL----MESGLQIQKSPEPEVLSTQEDLFD 308
             P    +E +  S       M     +    L    + S   + + PE    S    ++ 
Sbjct: 3723 TPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPS-VYT 3781

Query: 309  QSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSLSTNSSDLVAPSPD 368
              + T +S+G S+P+  EG         TT   +  + +RS +  ++  +   +++PS  
Sbjct: 3782 SMSMTTASEGSSSPTTLEG---------TTTMPMSTTSERSTLLTTVLISPISVMSPSEA 3832

Query: 369  AFRSTPFIVPSSP---TEQEGRQDKPMDTSV----LSEEGGEPFQKKLQS--------GE 413
            +  STP    S+P   + + G    P + +     ++ E   P    L S        G 
Sbjct: 3833 STLSTPPGDTSTPLLTSTKAGSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGA 3892

Query: 414  PVELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQF-SHDIFIPSPSLEEQSN 472
             +    PPL   +T +P   T  + + PV    S+ + ++       IFIPS  +   + 
Sbjct: 3893 SI-ASTPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTA 3951

Query: 473  D 473
            D
Sbjct: 3952 D 3952


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 67.8 bits (164), Expect = 1e-10
 Identities = 140/658 (21%), Positives = 253/658 (38%), Gaps = 85/658 (12%)

Query: 228  IAEQSSKDIPVTAQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSA-QELME 286
            I  +S + I V  +  K+  +V+EQ      +E++    +      E KE+    +E  E
Sbjct: 436  IKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAE 495

Query: 287  SGLQIQKSPEPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSG 346
             G +  KSP  E  ++ E                +P +EE     A +PA        S 
Sbjct: 496  GGEEETKSPPAEEAASPE------------KEAKSPVKEE-----AKSPAEA-----KSP 533

Query: 347  QRSLVQDSLSTNSSDLV-APSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPF 405
            ++   +      S +   +P+ +  +S P     SP ++E +    + +    E+   P 
Sbjct: 534  EKEEAKSPAEVKSPEKAKSPAKEEAKSPP--EAKSPEKEEAKSPAEVKS---PEKAKSPA 588

Query: 406  QKKLQSGEPVELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIP-SQPQFSHDIFIPS 464
            +++ +S  P E ++P    +S V  +A +P    +PV      P     P+ +      S
Sbjct: 589  KEEAKS--PAEAKSPE-KAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKA-----KS 640

Query: 465  PSLEEQSNDGKKDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQ 524
            P+ EE  +  K        + + E +K+       SPE     +  ++     + S   +
Sbjct: 641  PTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKE 700

Query: 525  SPKMESLSSHRIDEDGENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDD 584
              K    +   + E+ ++ +    +  SPV      P +  S +   A+  E   S    
Sbjct: 701  EAKSPEKAKSPVKEEAKSPE----KAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKA 756

Query: 585  KTKGDDTDTRDDISILATGCKGREETVA-EDVCIDLTCDSGSQAVPSPATRSEALSSVLD 643
            KT         D+         +EE  +  D   +       + V SP    +A S + +
Sbjct: 757  KTL--------DVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSP---EKAKSPLKE 805

Query: 644  QEEAMEIKEHHPEEGSSGSEVEEIP-ETPCESQGEELKEENMESVPLHLSLTETQSQGLC 702
              +A E +    EE  S  + EE P E   +   ++ +EE   + P      +T+ +   
Sbjct: 806  DAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATP------KTEEKKDS 859

Query: 703  LQKEMPKKECSEAMEVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVK 762
             ++E PKKE  +    E    +++ P+     + ++E K++EA      ED   V    K
Sbjct: 860  KKEEAPKKEAPKPKVEEKKEPAVEKPK-----ESKVEAKKEEA------EDKKKVPTPEK 908

Query: 763  EPSPRVDV--SCEPLEGVE----KCSDSQSWEDIAP-EIEPCAENRLDTKEEKSVEYEGD 815
            E   +V+V    +P E  E    +  D+++ E   P E +  A  + DTKEEK+ + E  
Sbjct: 909  EAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEK 968

Query: 816  LKSGTAETEPVEQDSSQPSLPLVRADDPLRLDQELQQPQTQEKTSNSLTEDSKMANAK 873
             K+     E  +  S +PS P        + ++     Q   K     TED K A  K
Sbjct: 969  PKTEAKAKEDDKTLSKEPSKPKAE-----KAEKSSSTDQKDSKPPEKATED-KAAKGK 1020



 Score = 65.9 bits (159), Expect = 4e-10
 Identities = 136/665 (20%), Positives = 252/665 (37%), Gaps = 84/665 (12%)

Query: 508  LTGDSCKLMLSTSEYSQS---PKMESLSSHRIDEDGENTQIEDTEPMSPVLNSKFVPAEN 564
            L G+ C++      +S     PK+ S+S+H         +++  E +  V  S     E 
Sbjct: 406  LEGEECRIGFGPIPFSLPEGLPKIPSVSTH--------IKVKSEEKIKVVEKS-----EK 452

Query: 565  DSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDISILATGCKGREETVAEDVCIDLTCDSG 624
            +++++   Q  E Q+++  + T+ ++ + +++        +G+EE   E+       + G
Sbjct: 453  ETVIVEE-QTEETQVTE--EVTEEEEKEAKEE--------EGKEEEGGEEE----EAEGG 497

Query: 625  SQAVPSP------ATRSEALSSVLDQEEA-MEIKEHHPEEGSSGSEVEEIPETPCESQGE 677
             +   SP      +   EA S V ++ ++  E K    EE  S +EV+  PE       E
Sbjct: 498  EEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKS-PEKAKSPAKE 556

Query: 678  ELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSEAMEVETSVISIDSPQKLAILDQE 737
            E K       P      E +      + + P+K  S A E   S     SP+K     +E
Sbjct: 557  EAKS------PPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKE 610

Query: 738  LEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPLEGVEKCSDSQSWEDIAPEIEPC 797
                  EA      E  S    +VK P      + E  +  EK    +  E  +PE    
Sbjct: 611  EAKSPAEAKSPVKEEAKSPA--EVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKS 668

Query: 798  ---AENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSLPLVRADDPLRLDQELQQP- 853
               AE +   K +  V+ E   KS      PV++++  P        +  +  ++ + P 
Sbjct: 669  PVKAEAKSPEKAKSPVKAEA--KSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPV 726

Query: 854  ----QTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAH--ASQSFCESSSETPFHFT 907
                +T EK  + + E++K     +    A+   +  P A   A +     + + P    
Sbjct: 727  KEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAK 786

Query: 908  LPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDVMSESMVETHDPI 967
             P + ++  P    +P     LK + K     I      +S +   +   E  V+  +P 
Sbjct: 787  SPVKEEVKSPEKAKSP-----LKEDAKAPEKEIPKKEEVKSPVKEEEKPQE--VKVKEPP 839

Query: 968  LGSGKGDSGAAPDVDDKLCLRMKLVSPETEAS----EESLQFNLEKPATG--ERKNGSTA 1021
              + +  + A P  ++K   + K  +P+ EA     EE  +  +EKP     E K     
Sbjct: 840  KKAEEEKAPATPKTEEKKDSK-KEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAE 898

Query: 1022 VAESVASPQKTMSVLSCICE---ARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKEKLE 1078
              + V +P+K       + E    +++ E   ++P     +      PS   E+++   E
Sbjct: 899  DKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKE-----PSKPAEKKEAAPE 953

Query: 1079 GDHTIRQSQQPMKPIS-PVKDPVSPASQKMVIQGPSSPQGEAMVTDVLEDQKEGRSTNKE 1137
               T  + ++  KP   P  +  +    K + + PS P+ E        DQK+ +   K 
Sbjct: 954  KKDT--KEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKA 1011

Query: 1138 NPSKA 1142
               KA
Sbjct: 1012 TEDKA 1016



 Score = 48.9 bits (115), Expect = 5e-05
 Identities = 128/672 (19%), Positives = 245/672 (36%), Gaps = 114/672 (16%)

Query: 633  TRSEALSSVLD--QEEAMEIKEHHPEEGSSGSEV-----EEIPETPCESQGEELKEENME 685
            T  EAL S  D  + +  E+++ H  + +S  E       E+  T  E   +  + +++ 
Sbjct: 330  TELEALKSTKDSLERQRSELEDRHQADIASYQEAIQQLDAELRNTKWEMAAQLREYQDLL 389

Query: 686  SVPLHLSLTETQSQGLCLQKEMPKKECSEAMEVETSVISIDSPQ---KLAILDQELEHKE 742
            +V + L +     +    +K +  +EC     +    I    P+   K+  +   ++ K 
Sbjct: 390  NVKMALDI-----EIAAYRKLLEGEEC----RIGFGPIPFSLPEGLPKIPSVSTHIKVKS 440

Query: 743  QEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPLEGVEKCSDSQSWEDIAPEIEPCAENRL 802
            +E  +     +   VIV+                  E+  ++Q  E++  E E  A+   
Sbjct: 441  EEKIKVVEKSEKETVIVE------------------EQTEETQVTEEVTEEEEKEAKEEE 482

Query: 803  DTKEEKSVEYEG-----DLKSGTAE---------TEPVEQDSSQPSLPLVRADDPLRLDQ 848
              +EE   E E      + KS  AE           PV++++  P+       +  +   
Sbjct: 483  GKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPA 542

Query: 849  ELQQPQ---TQEKTSNSLTEDSKMANAKQLSSDAEA---QKLGKPSAHASQSFCESSS-- 900
            E++ P+   +  K       ++K    ++  S AE    +K   P+   ++S  E+ S  
Sbjct: 543  EVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPE 602

Query: 901  ----------ETPFHFTLPKEGDIIPPLTGATP-----PLIGHLKLEPKRHSTPIGISNY 945
                      ++P     P + +   P    +P     P     K   K  S     +  
Sbjct: 603  KAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKS 662

Query: 946  PESTIATSDVMSESMVETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSP---ETEASEES 1002
            PE   +     ++S  +   P+    K    A   V ++     K  SP   E ++ E++
Sbjct: 663  PEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKA 722

Query: 1003 LQFNLEKPATGERKNGSTAVAESVASPQ--------KTMSVLSCICEARQENEARS---- 1050
                 E+  T E+    + V E   SP+        KT+ V S   +   + EARS    
Sbjct: 723  KSPVKEEAKTPEK--AKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADK 780

Query: 1051 -EDPPTTPIRGNLLHFPSSQGEEEKEKLEGDHTIRQSQQPMKP--ISPVKDPVSPASQKM 1107
              +   +P++  +        E+ K  L+ D    + + P K    SPVK+   P   K+
Sbjct: 781  FPEKAKSPVKEEV-----KSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKV 835

Query: 1108 VIQGPSSPQGEAMVTDVLEDQKEGR---STNKENP-------SKALIERPSQNNIGIQTM 1157
                  + + +A  T   E++K+ +   +  KE P        +  +E+P ++ +  +  
Sbjct: 836  KEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKE 895

Query: 1158 EC----SLRVPETVSAATQTIKNVCEQGTSTVDQNFGKQDATVQTERGSGEKPVSAP-GD 1212
            E      +  PE  + A   +K   +    T        DA  +      EK  +AP   
Sbjct: 896  EAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKK 955

Query: 1213 DTESLHSQGEEE 1224
            DT+   ++  EE
Sbjct: 956  DTKEEKAKKPEE 967



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 142/695 (20%), Positives = 262/695 (37%), Gaps = 138/695 (19%)

Query: 108  IEQLPQPNRTSSVLGMSVESAPAVEE-EKGEELEQKEKEKEEDTSGNTTHSLGAEDTASS 166
            I+ + +  + + ++    E     EE  + EE E KE+E +E+  G    + G E     
Sbjct: 444  IKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGE----- 498

Query: 167  QLGFGVLELSQSQDVEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDI 226
                   E ++S   EE   P   +KE    V   +     S  +A +  K E +S  ++
Sbjct: 499  -------EETKSPPAEEAASP---EKEAKSPVKEEA----KSPAEAKSPEKEEAKSPAEV 544

Query: 227  PIAEQSSKDIPVTAQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELME 286
               E++         P+K+    + ++PP A+S              E +E  S  E+  
Sbjct: 545  KSPEKAK-------SPAKE----EAKSPPEAKSP-------------EKEEAKSPAEV-- 578

Query: 287  SGLQIQKSPEPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSG 346
                  KSPE      +E+    + +  S +   +P +EE     A +PA          
Sbjct: 579  ------KSPEKAKSPAKEEAKSPA-EAKSPEKAKSPVKEE-----AKSPAEA-------- 618

Query: 347  QRSLVQDSLSTNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQ 406
             +S V++      S     SP+  +S        PT++E +  +    S   EE   P +
Sbjct: 619  -KSPVKEEA---KSPAEVKSPEKAKS--------PTKEEAKSPEKA-KSPEKEEAKSPEK 665

Query: 407  KKLQSGEPVELE-NPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSP 465
             K     PV+ E   P   +S V  +A +P    +PV      P  ++          SP
Sbjct: 666  AK----SPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAK----------SP 711

Query: 466  SLEEQSNDGKKDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQS 525
              EE  +  K    +   + T E +K+   E   SPE    + + +  K +   S  +++
Sbjct: 712  VKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEK---AKSPEKAKTLDVKSPEAKT 768

Query: 526  PKMESLSSHRIDEDGENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDD- 584
            P  E   S   D+  E  +       SPV      P +  S L   A+  E ++ + ++ 
Sbjct: 769  PAKEEARS-PADKFPEKAK-------SPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEV 820

Query: 585  KTKGDDTDTRDDISILATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQ 644
            K+   + +   ++ +     K  EE               + A P    + ++      +
Sbjct: 821  KSPVKEEEKPQEVKVKEPPKKAEEEK--------------APATPKTEEKKDSKKEEAPK 866

Query: 645  EEAMEIKEHHPEEGSSGSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQ 704
            +EA + K    +E +    VE+  E+  E++ EE +++     P   +  + + +     
Sbjct: 867  KEAPKPKVEEKKEPA----VEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKP 922

Query: 705  K---EMPKKECSEAMEVETSVISID---SPQKLAILDQELEHKEQEAWEEATSEDSSVVI 758
            K   E+ KKE  +A   E S  +     +P+K    +++ +  E++   EA +++    +
Sbjct: 923  KEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTL 982

Query: 759  VDVKEPSPRVDVSCEPLEGVEKCSDSQSWEDIAPE 793
               KEPS          E  EK S +   +   PE
Sbjct: 983  --SKEPSK------PKAEKAEKSSSTDQKDSKPPE 1009


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 232/1220 (19%), Positives = 442/1220 (36%), Gaps = 229/1220 (18%)

Query: 198  VTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTAQPSKDVH---VVKEQNP 254
            VTT S  ++ S     T+ K +    +D+  A +  K  P+  QP+  +H     K + P
Sbjct: 666  VTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPT--LHGSPSAKAKQP 723

Query: 255  PPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSPEPEVLSTQEDLFDQSNKTV 314
            P A S   P  PK      E  +   A +         K  +P+++    DL   S+ T 
Sbjct: 724  PEADSLSKPAPPKEPSVPSEQDKAPVADD---------KPKQPKMVKPTTDLVSSSSATT 774

Query: 315  SSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSLSTNSSDLVAPSPDAFRSTP 374
              D  S  S+ +      +TP              L  DS   + S      P   + +P
Sbjct: 775  KPDIPS--SKVQSQAEEKTTPP-------------LKTDSAKPSQSF----PPTGEKVSP 815

Query: 375  FIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELENPPLLPESTVSPQAST 434
            F   + P           D+ ++S  G     K  +  +PV+ +  P   ++ +SP+   
Sbjct: 816  FDSKAIPRPAS-------DSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDA 868

Query: 435  -PISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGKKDGDMHSSSLTVECSKTS 493
             P+ + +P  PPG  P   Q        +P+P    +  +  +   ++  S+T +  K+ 
Sbjct: 869  KPMPKGSPT-PPGPRPTAGQT-------VPTPQQSPKPQEQSRRFSLNLGSIT-DAPKSQ 919

Query: 494  EIEPKNSPE----DLGLSLTGDSCKLMLSTSE---YSQS-PKMESLSSHRIDEDGENTQI 545
               P+ +        G S+   +  L+ +  +   +SQS P      +    +   +   
Sbjct: 920  PTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGP 979

Query: 546  EDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTD-----TRDDISIL 600
              +   +P   +K +P + ++    PA +     ++     K  +T+      +D  S+ 
Sbjct: 980  PKSTGQAPPAPAKSIPVKKET--KAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLT 1037

Query: 601  ATGCKG------REETVAEDVC--IDLTCDSGSQAVPSPATRSEALSSVLD------QEE 646
            A   K        +    E  C       + GS+  P+  T +E  + V +         
Sbjct: 1038 AEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPH 1097

Query: 647  AMEIKEH-----HPEEGSSG--SEVEEIPETPCESQGEEL-----KEENMESVPLHLSLT 694
              EI+E        +   SG   ++ ++P  P   +   +           +VP  + L 
Sbjct: 1098 LTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLV 1157

Query: 695  ETQSQGLCLQKE---MPKKECSEAMEVETSVISIDSPQKLAILDQEL-----------EH 740
            + Q Q +  + E   + K + + +ME    +++ D  Q+ + L+++            E 
Sbjct: 1158 KKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEE 1217

Query: 741  KEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPLEGVEKCSDSQSWEDIAPEIEPCAEN 800
            K+    EE    +    +++ K+P+P  D    P E      + Q  + +  +++  AE 
Sbjct: 1218 KKLIPEEEKIRSEEKKPLLEEKKPTPE-DKKLLP-EAKTSAPEEQKHDLLKSQVQ-IAEE 1274

Query: 801  RLDTKEEKSVEYEG--------DLKSGTAETEPVEQDSS------QPSLPLVRADDPLRL 846
            +L+ +       EG         L SGT ++ P E D +      QP  P     D +  
Sbjct: 1275 KLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEP 1334

Query: 847  DQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSFCESSSETPFHF 906
             +E    +T+++   S T  S+   + Q  SD         + ++S     S  E P   
Sbjct: 1335 GKE----KTEKEDDKSDTSSSQQPKSPQGLSD---------TGYSSDGISSSLGEIP--- 1378

Query: 907  TLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYP--ESTIATSDVMSESMVETH 964
                   +IP  T     L G  K    + S+P   S+    EST+        S++E  
Sbjct: 1379 ------SLIP--TDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVL-------SILEAQ 1423

Query: 965  DPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGERKNGSTAVAE 1024
               L   K +    P            VSPE    +E  Q                    
Sbjct: 1424 ASTLADEKSEKKTQPHE----------VSPEQPKDQEKTQ-------------------- 1453

Query: 1025 SVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKEKLEGDHTIR 1084
               S  +T+ +     E ++  E R +    T  + +    PSS+  +EK +   D T R
Sbjct: 1454 ---SLSETLEITISEEEIKESQEERKD----TFKKDSQQDIPSSKDHKEKSEFVDDITTR 1506

Query: 1085 QSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVTDVLEDQKEGRSTNKENPSKALI 1144
            +     +P   V++     +  +  +   +  G +   +  ++  +G    ++   K +I
Sbjct: 1507 R-----EPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQII 1561

Query: 1145 ERPSQNNI-GIQTMECSLRVPETVSAATQTIKNVCEQGTSTVDQNFGKQDATVQTERGSG 1203
            E  +  +  G +  E      + +S++T++ K          ++  GK   T    R   
Sbjct: 1562 EMSADEDASGSEDDEFIRNQLKEISSSTESQKK---------EETKGKGKITAGKHRRLT 1612

Query: 1204 EKPVSAPGDDT---ESLHSQGEEEFD-MPQPPHGHVLHRHMRT--------IREVRTL-V 1250
             K  ++  +D     S H + +E FD  P+  +     +            +R  +T+ +
Sbjct: 1613 RKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRETKSQESEELVVTGGGGLRRFKTIEL 1672

Query: 1251 TRVITDVYYVDGTEVERKVTEETEEPIVECQECETEVSPSQTGGSSGDLGDISSFSSKAS 1310
               I D Y  + ++ +  +  + EEP +E +     ++ S    S G+     S S  AS
Sbjct: 1673 NSTIADKYSAESSQKKTSLYFD-EEPELEME----SLTDSPEDRSRGE----GSSSLHAS 1723

Query: 1311 SLHRTSSGTSLSAMHSSGSS 1330
            S    +S TS+S++     S
Sbjct: 1724 SFTPGTSPTSVSSLDEDSDS 1743



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 149/724 (20%), Positives = 265/724 (36%), Gaps = 111/724 (15%)

Query: 18   PCLIIEDSQPESQVLEDDSGSHFSMLSRHLPNLQTHKENPVLDVVSNPEQT-AGEERGDG 76
            P  + E  QP++++    SG+  S+        +T KE P     + P+Q   G+E    
Sbjct: 1282 PKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKE---- 1337

Query: 77   NSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPNRTSSVLGMSVESAPAVEEEKG 136
                    K  K  D  D+S+     S   + +     +  SS LG      P  E++  
Sbjct: 1338 --------KTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDIL 1389

Query: 137  EELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQSQDVEENTVPYEV------ 190
            + L +K+   +E +  + +     E T  S L      L+  +  E+ T P+EV      
Sbjct: 1390 KGL-KKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKS-EKKTQPHEVSPEQPK 1447

Query: 191  DKEQLQSVTTNSGYT----RLSDVDANTAIKHEEQSNEDIPIAEQSSK------DIPVTA 240
            D+E+ QS++     T     + +         ++ S +DIP ++   +      DI    
Sbjct: 1448 DQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRR 1507

Query: 241  QP--SKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQ---IQKSP 295
            +P  S +     E +P P R         +S    +   Q S +E  E  ++   I+ S 
Sbjct: 1508 EPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEE--EDFIRKQIIEMSA 1565

Query: 296  EPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSL 355
            + +   +++D F ++     S    +  +EE   +      T     +L+ + S   D  
Sbjct: 1566 DEDASGSEDDEFIRNQLKEISSSTESQKKEE---TKGKGKITAGKHRRLTRKSSTSIDED 1622

Query: 356  STNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPV 415
            +           +AF  +P        E + R+ K  ++  L   GG      L+  + +
Sbjct: 1623 AGRRHSWHDEDDEAFDESP--------ELKYRETKSQESEELVVTGG----GGLRRFKTI 1670

Query: 416  ELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGK 475
            EL        ST++ + S   SQ        SL    +P+   +    SP   E  + G+
Sbjct: 1671 EL-------NSTIADKYSAESSQKKT-----SLYFDEEPELEMESLTDSP---EDRSRGE 1715

Query: 476  KDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHR 535
                +H+SS T          P  SP  +  SL  DS     S S      K +  + HR
Sbjct: 1716 GSSSLHASSFT----------PGTSPTSVS-SLDEDSDS---SPSHKKGESKQQRKARHR 1761

Query: 536  IDEDGENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRD 595
                   T IED+     +        E + +L    +  E++  Q    +K    D +D
Sbjct: 1762 PHGPLLPT-IEDSSEEEEL-------REEEELLKEQEKQREIEQQQRKSSSKKSKKD-KD 1812

Query: 596  DISILATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHP 655
            ++       + R E                +  PS  +  E  S   +  +A E++E H 
Sbjct: 1813 ELR-----AQRRRER--------------PKTPPSNLSPIEDASPTEELRQAAEMEELHR 1853

Query: 656  EEGSSGS-EVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSE 714
               S  S  +E  PE    S  + ++ + +  +P  +SL     +   +QKE  +K    
Sbjct: 1854 SSCSEYSPSIESDPEGFEISPEKIIEVQKVYKLPTAVSLYSPTDEQSIMQKEGSQKALKS 1913

Query: 715  AMEV 718
            A E+
Sbjct: 1914 AEEM 1917



 Score = 37.7 bits (86), Expect = 0.11
 Identities = 152/794 (19%), Positives = 254/794 (31%), Gaps = 127/794 (15%)

Query: 158 LGAEDTASSQLGF--GVLELSQSQDVEENTVPYEV--DKEQLQSVTTNSGYTRLSDVDAN 213
           L  E  +S   GF   V  LS    V     P+++  D E  Q  TT             
Sbjct: 144 LKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKK----------Q 193

Query: 214 TAIKHEEQSNEDI---PIAEQSSKDIPVTAQPSKDV---------------HVVKEQNPP 255
             ++ E+   E I   P+ +Q  K IP    P +D                  +K Q P 
Sbjct: 194 KVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPG 253

Query: 256 PARSEDMPF-SPKASVAAMEAKEQLSAQELMESGLQIQKSPEPEVLSTQEDLFDQSNK-- 312
             +    P  +P+   A +  +   S  +  ++ +   +S +P + S  +    Q     
Sbjct: 254 TGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGK 313

Query: 313 --------TVSSDGCSTPSREEGGCS--LASTPATTLHLLQLSGQRSLVQDSLS------ 356
                     S  G + P  +  G +  LA  P T    +Q  G        L       
Sbjct: 314 PPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPA 373

Query: 357 ----TNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDT----SVLSEEGG--EPFQ 406
               +       P P A    P  V  +P +Q G    P         L+++ G   P +
Sbjct: 374 QQTGSEKPSSEQPGPKALAQPPG-VGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAK 432

Query: 407 KKLQSGEPVELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPS 466
               +  PV+   P  +P     P   T   Q+ P  PP  LP P++P        P P+
Sbjct: 433 APGPTKTPVQQPGPGKIPAQQAGP-GKTSAQQTGPTKPPSQLPGPAKPPPQQ----PGPA 487

Query: 467 LEEQSNDGKKDGDMHSSSLTVECSKTSEIEP---KNSPEDLGLSLTGDSCKLMLSTSEYS 523
                  G           T    K    +P   K SP+  G            ST   S
Sbjct: 488 KPPPQQPGSAKPPSQQPGST----KPPPQQPGPAKPSPQQPG------------STKPPS 531

Query: 524 QSPKMESLSSHRIDEDGENTQIEDTEPMSPVLNSKFV--PAENDSILMNPAQ-------- 573
           Q P     S+ +      + Q + T+P+S   + K +  P  + S    P+Q        
Sbjct: 532 QQPGSAKPSAQQPSPAKPSAQ-QSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICP 590

Query: 574 ---DGEVQLSQNDDKTKGDDTDTRDDI-SILATGCKGREETVAEDVCIDLTCDS--GSQA 627
                E+ L   +       T+ +  + S+           V E +C++       G   
Sbjct: 591 LCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDL 650

Query: 628 VPSPATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEVEEIPETPCESQGEELKEENMESV 687
            P P++    L +         + +  P+   +  + +  P+       E  K   +   
Sbjct: 651 APVPSSPQPKLKTA-PVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQ 709

Query: 688 P-LHLSLTETQSQ---GLCLQKEMPKKECSEAMEVETSVISIDSPQKLAILDQELE---- 739
           P LH S +    Q      L K  P KE S   E + + ++ D P++  ++    +    
Sbjct: 710 PTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSS 769

Query: 740 -----------HKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPLEG---VEKCSDSQ 785
                       K Q   EE T+           +  P       P +        SDS+
Sbjct: 770 SSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSK 829

Query: 786 SWEDIAPEIEPCAENRLDTKEEKSVEYEGDLK-SGTAETEPVEQDSSQPSLPLVRADDPL 844
                 P  E   + ++D  ++K    +   K S   + +P+ + S  P  P   A   +
Sbjct: 830 IISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTV 889

Query: 845 RLDQELQQPQTQEK 858
              Q+  +PQ Q +
Sbjct: 890 PTPQQSPKPQEQSR 903



 Score = 33.1 bits (74), Expect = 2.8
 Identities = 24/120 (20%), Positives = 48/120 (40%), Gaps = 4/120 (3%)

Query: 1007 LEKPATGERKNGSTAVAESVASPQKTM--SVLSCICEARQENEARSEDPPTTPIRGNLLH 1064
            +  P+   R +    + + +++P+KT     L C  EA  + ++      T+P +     
Sbjct: 3534 IRTPSIRARVDAKVEIIKHISAPEKTYKGGSLGCQTEADSDTQSPQYLSATSPPKDKKRP 3593

Query: 1065 FPSSQGEEEKEKLEGDHTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVTDV 1124
             P   G      L  D T++ +  P K    +  P+SP S    ++    P  + +  D+
Sbjct: 3594 TPLEIG--YSSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKALESAFVPYEKPLPDDI 3651


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 232/1220 (19%), Positives = 442/1220 (36%), Gaps = 229/1220 (18%)

Query: 198  VTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTAQPSKDVH---VVKEQNP 254
            VTT S  ++ S     T+ K +    +D+  A +  K  P+  QP+  +H     K + P
Sbjct: 666  VTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPT--LHGSPSAKAKQP 723

Query: 255  PPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSPEPEVLSTQEDLFDQSNKTV 314
            P A S   P  PK      E  +   A +         K  +P+++    DL   S+ T 
Sbjct: 724  PEADSLSKPAPPKEPSVPSEQDKAPVADD---------KPKQPKMVKPTTDLVSSSSATT 774

Query: 315  SSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSLSTNSSDLVAPSPDAFRSTP 374
              D  S  S+ +      +TP              L  DS   + S      P   + +P
Sbjct: 775  KPDIPS--SKVQSQAEEKTTPP-------------LKTDSAKPSQSF----PPTGEKVSP 815

Query: 375  FIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELENPPLLPESTVSPQAST 434
            F   + P           D+ ++S  G     K  +  +PV+ +  P   ++ +SP+   
Sbjct: 816  FDSKAIPRPAS-------DSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDA 868

Query: 435  -PISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGKKDGDMHSSSLTVECSKTS 493
             P+ + +P  PPG  P   Q        +P+P    +  +  +   ++  S+T +  K+ 
Sbjct: 869  KPMPKGSPT-PPGPRPTAGQT-------VPTPQQSPKPQEQSRRFSLNLGSIT-DAPKSQ 919

Query: 494  EIEPKNSPE----DLGLSLTGDSCKLMLSTSE---YSQS-PKMESLSSHRIDEDGENTQI 545
               P+ +        G S+   +  L+ +  +   +SQS P      +    +   +   
Sbjct: 920  PTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGP 979

Query: 546  EDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTD-----TRDDISIL 600
              +   +P   +K +P + ++    PA +     ++     K  +T+      +D  S+ 
Sbjct: 980  PKSTGQAPPAPAKSIPVKKET--KAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLT 1037

Query: 601  ATGCKG------REETVAEDVC--IDLTCDSGSQAVPSPATRSEALSSVLD------QEE 646
            A   K        +    E  C       + GS+  P+  T +E  + V +         
Sbjct: 1038 AEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPH 1097

Query: 647  AMEIKEH-----HPEEGSSG--SEVEEIPETPCESQGEEL-----KEENMESVPLHLSLT 694
              EI+E        +   SG   ++ ++P  P   +   +           +VP  + L 
Sbjct: 1098 LTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLV 1157

Query: 695  ETQSQGLCLQKE---MPKKECSEAMEVETSVISIDSPQKLAILDQEL-----------EH 740
            + Q Q +  + E   + K + + +ME    +++ D  Q+ + L+++            E 
Sbjct: 1158 KKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEE 1217

Query: 741  KEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPLEGVEKCSDSQSWEDIAPEIEPCAEN 800
            K+    EE    +    +++ K+P+P  D    P E      + Q  + +  +++  AE 
Sbjct: 1218 KKLIPEEEKIRSEEKKPLLEEKKPTPE-DKKLLP-EAKTSAPEEQKHDLLKSQVQ-IAEE 1274

Query: 801  RLDTKEEKSVEYEG--------DLKSGTAETEPVEQDSS------QPSLPLVRADDPLRL 846
            +L+ +       EG         L SGT ++ P E D +      QP  P     D +  
Sbjct: 1275 KLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEP 1334

Query: 847  DQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSFCESSSETPFHF 906
             +E    +T+++   S T  S+   + Q  SD         + ++S     S  E P   
Sbjct: 1335 GKE----KTEKEDDKSDTSSSQQPKSPQGLSD---------TGYSSDGISSSLGEIP--- 1378

Query: 907  TLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYP--ESTIATSDVMSESMVETH 964
                   +IP  T     L G  K    + S+P   S+    EST+        S++E  
Sbjct: 1379 ------SLIP--TDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVL-------SILEAQ 1423

Query: 965  DPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGERKNGSTAVAE 1024
               L   K +    P            VSPE    +E  Q                    
Sbjct: 1424 ASTLADEKSEKKTQPHE----------VSPEQPKDQEKTQ-------------------- 1453

Query: 1025 SVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKEKLEGDHTIR 1084
               S  +T+ +     E ++  E R +    T  + +    PSS+  +EK +   D T R
Sbjct: 1454 ---SLSETLEITISEEEIKESQEERKD----TFKKDSQQDIPSSKDHKEKSEFVDDITTR 1506

Query: 1085 QSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVTDVLEDQKEGRSTNKENPSKALI 1144
            +     +P   V++     +  +  +   +  G +   +  ++  +G    ++   K +I
Sbjct: 1507 R-----EPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQII 1561

Query: 1145 ERPSQNNI-GIQTMECSLRVPETVSAATQTIKNVCEQGTSTVDQNFGKQDATVQTERGSG 1203
            E  +  +  G +  E      + +S++T++ K          ++  GK   T    R   
Sbjct: 1562 EMSADEDASGSEDDEFIRNQLKEISSSTESQKK---------EETKGKGKITAGKHRRLT 1612

Query: 1204 EKPVSAPGDDT---ESLHSQGEEEFD-MPQPPHGHVLHRHMRT--------IREVRTL-V 1250
             K  ++  +D     S H + +E FD  P+  +     +            +R  +T+ +
Sbjct: 1613 RKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRETKSQESEELVVTGGGGLRRFKTIEL 1672

Query: 1251 TRVITDVYYVDGTEVERKVTEETEEPIVECQECETEVSPSQTGGSSGDLGDISSFSSKAS 1310
               I D Y  + ++ +  +  + EEP +E +     ++ S    S G+     S S  AS
Sbjct: 1673 NSTIADKYSAESSQKKTSLYFD-EEPELEME----SLTDSPEDRSRGE----GSSSLHAS 1723

Query: 1311 SLHRTSSGTSLSAMHSSGSS 1330
            S    +S TS+S++     S
Sbjct: 1724 SFTPGTSPTSVSSLDEDSDS 1743



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 149/724 (20%), Positives = 265/724 (36%), Gaps = 111/724 (15%)

Query: 18   PCLIIEDSQPESQVLEDDSGSHFSMLSRHLPNLQTHKENPVLDVVSNPEQT-AGEERGDG 76
            P  + E  QP++++    SG+  S+        +T KE P     + P+Q   G+E    
Sbjct: 1282 PKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKE---- 1337

Query: 77   NSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPNRTSSVLGMSVESAPAVEEEKG 136
                    K  K  D  D+S+     S   + +     +  SS LG      P  E++  
Sbjct: 1338 --------KTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDIL 1389

Query: 137  EELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQSQDVEENTVPYEV------ 190
            + L +K+   +E +  + +     E T  S L      L+  +  E+ T P+EV      
Sbjct: 1390 KGL-KKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKS-EKKTQPHEVSPEQPK 1447

Query: 191  DKEQLQSVTTNSGYT----RLSDVDANTAIKHEEQSNEDIPIAEQSSK------DIPVTA 240
            D+E+ QS++     T     + +         ++ S +DIP ++   +      DI    
Sbjct: 1448 DQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRR 1507

Query: 241  QP--SKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQ---IQKSP 295
            +P  S +     E +P P R         +S    +   Q S +E  E  ++   I+ S 
Sbjct: 1508 EPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEE--EDFIRKQIIEMSA 1565

Query: 296  EPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSL 355
            + +   +++D F ++     S    +  +EE   +      T     +L+ + S   D  
Sbjct: 1566 DEDASGSEDDEFIRNQLKEISSSTESQKKEE---TKGKGKITAGKHRRLTRKSSTSIDED 1622

Query: 356  STNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPV 415
            +           +AF  +P        E + R+ K  ++  L   GG      L+  + +
Sbjct: 1623 AGRRHSWHDEDDEAFDESP--------ELKYRETKSQESEELVVTGG----GGLRRFKTI 1670

Query: 416  ELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGK 475
            EL        ST++ + S   SQ        SL    +P+   +    SP   E  + G+
Sbjct: 1671 EL-------NSTIADKYSAESSQKKT-----SLYFDEEPELEMESLTDSP---EDRSRGE 1715

Query: 476  KDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHR 535
                +H+SS T          P  SP  +  SL  DS     S S      K +  + HR
Sbjct: 1716 GSSSLHASSFT----------PGTSPTSVS-SLDEDSDS---SPSHKKGESKQQRKARHR 1761

Query: 536  IDEDGENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRD 595
                   T IED+     +        E + +L    +  E++  Q    +K    D +D
Sbjct: 1762 PHGPLLPT-IEDSSEEEEL-------REEEELLKEQEKQREIEQQQRKSSSKKSKKD-KD 1812

Query: 596  DISILATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHP 655
            ++       + R E                +  PS  +  E  S   +  +A E++E H 
Sbjct: 1813 ELR-----AQRRRER--------------PKTPPSNLSPIEDASPTEELRQAAEMEELHR 1853

Query: 656  EEGSSGS-EVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSE 714
               S  S  +E  PE    S  + ++ + +  +P  +SL     +   +QKE  +K    
Sbjct: 1854 SSCSEYSPSIESDPEGFEISPEKIIEVQKVYKLPTAVSLYSPTDEQSIMQKEGSQKALKS 1913

Query: 715  AMEV 718
            A E+
Sbjct: 1914 AEEM 1917



 Score = 37.7 bits (86), Expect = 0.11
 Identities = 152/794 (19%), Positives = 254/794 (31%), Gaps = 127/794 (15%)

Query: 158 LGAEDTASSQLGF--GVLELSQSQDVEENTVPYEV--DKEQLQSVTTNSGYTRLSDVDAN 213
           L  E  +S   GF   V  LS    V     P+++  D E  Q  TT             
Sbjct: 144 LKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKK----------Q 193

Query: 214 TAIKHEEQSNEDI---PIAEQSSKDIPVTAQPSKDV---------------HVVKEQNPP 255
             ++ E+   E I   P+ +Q  K IP    P +D                  +K Q P 
Sbjct: 194 KVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPG 253

Query: 256 PARSEDMPF-SPKASVAAMEAKEQLSAQELMESGLQIQKSPEPEVLSTQEDLFDQSNK-- 312
             +    P  +P+   A +  +   S  +  ++ +   +S +P + S  +    Q     
Sbjct: 254 TGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGK 313

Query: 313 --------TVSSDGCSTPSREEGGCS--LASTPATTLHLLQLSGQRSLVQDSLS------ 356
                     S  G + P  +  G +  LA  P T    +Q  G        L       
Sbjct: 314 PPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPA 373

Query: 357 ----TNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDT----SVLSEEGG--EPFQ 406
               +       P P A    P  V  +P +Q G    P         L+++ G   P +
Sbjct: 374 QQTGSEKPSSEQPGPKALAQPPG-VGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAK 432

Query: 407 KKLQSGEPVELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPS 466
               +  PV+   P  +P     P   T   Q+ P  PP  LP P++P        P P+
Sbjct: 433 APGPTKTPVQQPGPGKIPAQQAGP-GKTSAQQTGPTKPPSQLPGPAKPPPQQ----PGPA 487

Query: 467 LEEQSNDGKKDGDMHSSSLTVECSKTSEIEP---KNSPEDLGLSLTGDSCKLMLSTSEYS 523
                  G           T    K    +P   K SP+  G            ST   S
Sbjct: 488 KPPPQQPGSAKPPSQQPGST----KPPPQQPGPAKPSPQQPG------------STKPPS 531

Query: 524 QSPKMESLSSHRIDEDGENTQIEDTEPMSPVLNSKFV--PAENDSILMNPAQ-------- 573
           Q P     S+ +      + Q + T+P+S   + K +  P  + S    P+Q        
Sbjct: 532 QQPGSAKPSAQQPSPAKPSAQ-QSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICP 590

Query: 574 ---DGEVQLSQNDDKTKGDDTDTRDDI-SILATGCKGREETVAEDVCIDLTCDS--GSQA 627
                E+ L   +       T+ +  + S+           V E +C++       G   
Sbjct: 591 LCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDL 650

Query: 628 VPSPATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEVEEIPETPCESQGEELKEENMESV 687
            P P++    L +         + +  P+   +  + +  P+       E  K   +   
Sbjct: 651 APVPSSPQPKLKTA-PVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQ 709

Query: 688 P-LHLSLTETQSQ---GLCLQKEMPKKECSEAMEVETSVISIDSPQKLAILDQELE---- 739
           P LH S +    Q      L K  P KE S   E + + ++ D P++  ++    +    
Sbjct: 710 PTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSS 769

Query: 740 -----------HKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPLEG---VEKCSDSQ 785
                       K Q   EE T+           +  P       P +        SDS+
Sbjct: 770 SSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSK 829

Query: 786 SWEDIAPEIEPCAENRLDTKEEKSVEYEGDLK-SGTAETEPVEQDSSQPSLPLVRADDPL 844
                 P  E   + ++D  ++K    +   K S   + +P+ + S  P  P   A   +
Sbjct: 830 IISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTV 889

Query: 845 RLDQELQQPQTQEK 858
              Q+  +PQ Q +
Sbjct: 890 PTPQQSPKPQEQSR 903



 Score = 33.1 bits (74), Expect = 2.8
 Identities = 24/120 (20%), Positives = 48/120 (40%), Gaps = 4/120 (3%)

Query: 1007 LEKPATGERKNGSTAVAESVASPQKTM--SVLSCICEARQENEARSEDPPTTPIRGNLLH 1064
            +  P+   R +    + + +++P+KT     L C  EA  + ++      T+P +     
Sbjct: 3534 IRTPSIRARVDAKVEIIKHISAPEKTYKGGSLGCQTEADSDTQSPQYLSATSPPKDKKRP 3593

Query: 1065 FPSSQGEEEKEKLEGDHTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVTDV 1124
             P   G      L  D T++ +  P K    +  P+SP S    ++    P  + +  D+
Sbjct: 3594 TPLEIG--YSSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKALESAFVPYEKPLPDDI 3651


>gi|209862789 microtubule associated monoxygenase, calponin and LIM
            domain containing 3 isoform 1 [Homo sapiens]
          Length = 2002

 Score = 60.5 bits (145), Expect = 2e-08
 Identities = 100/409 (24%), Positives = 160/409 (39%), Gaps = 82/409 (20%)

Query: 103  SISQVIEQLPQPNRTSSVLGMSVE------SAPAVEEEKGEELEQKEKEKEEDTSGNT-- 154
            ++ +V E+    +  SSVL    E      S+ +  EE+GEE E++ +    D  G    
Sbjct: 905  ALQEVPEETQAEHNLSSVLDTGAEEDVASSSSESEMEEEGEEEEEEPRLPPSDLGGVPWK 964

Query: 155  ----THSL---GAEDTASSQLGFGVLELSQSQDVEENTVPYEVDKEQLQSVTTNSGYTRL 207
                 H+L    +E+   +   FG     + ++ EE     E D ++ +  ++ +G  RL
Sbjct: 965  EAVRIHALLKGKSEEELEASKSFGPGNEEEEEEEEEYEEEEEEDYDEEEEESSEAGNQRL 1024

Query: 208  SDV-----------DAN-TAIKHEEQSNEDIPIAEQSSKDIP---------VTAQPSKDV 246
              V           D + T I+  E+     P +E S+   P         V ++P++  
Sbjct: 1025 QQVMHAADPLEIQADVHWTHIREREEEERMAPASESSASGAPLDENDLEEDVDSEPAEIE 1084

Query: 247  HVVKEQNPP----PARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSPEPEVLST 302
                E   P        +D  +S   S A  E +    A+   E+ L+++ S + E L  
Sbjct: 1085 GEAAEDGDPGDTGAELDDDQHWSDSPSDADRELRLPCPAEG--EAELELRVSEDEEKLP- 1141

Query: 303  QEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSLSTNSSDL 362
                             ++P  +E G S A++P   +   Q S    +   S ST    L
Sbjct: 1142 -----------------ASPKHQERGPSQATSP---IRSPQESALLFIPVHSPSTEGPQL 1181

Query: 363  VAPSPDAFRSTP-----FIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVEL 417
              P P A +        F  P  P E+  + D P D   +      P +      +PV L
Sbjct: 1182 -PPVPAATQEKSPEERLFPEPLLPKEKP-KADAPSDLKAVHS----PIRS-----QPVTL 1230

Query: 418  ENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPS 466
                  P S  SPQ   P++ STP  PP  LPI SQPQ S +  +PSP+
Sbjct: 1231 PEART-PVSPGSPQPQPPVAASTP--PPSPLPICSQPQPSTEATVPSPT 1276



 Score = 35.0 bits (79), Expect = 0.73
 Identities = 84/388 (21%), Positives = 134/388 (34%), Gaps = 79/388 (20%)

Query: 571  PAQDGEVQ--------LSQNDDKTKGDDTDTRDDISILATGCKGREETVA-EDVCIDLTC 621
            P QDG           ++ + ++T G   +  ++ SI A   +G  E +  E+  + L  
Sbjct: 844  PLQDGATTDANGRANAVASSTERTPGSGVNGLEEPSI-AKRLRGTPERIELENYRLSLRQ 902

Query: 622  DSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEVEEIPETPCESQGEELKE 681
                Q VP        LSSVLD     ++        SS SE+EE        +GEE +E
Sbjct: 903  AEALQEVPEETQAEHNLSSVLDTGAEEDVAS-----SSSESEMEE--------EGEEEEE 949

Query: 682  EN------------MESVPLHLSLTETQSQGLCLQKEMPKKECSEAMEVETSVISIDSPQ 729
            E              E+V +H  L     + L   K        E  E            
Sbjct: 950  EPRLPPSDLGGVPWKEAVRIHALLKGKSEEELEASKSFGPGNEEEEEE------------ 997

Query: 730  KLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPLEGVEKCSDSQSWED 789
                 ++E E +E+E ++E   E S        +   +V  + +PLE          W  
Sbjct: 998  -----EEEYEEEEEEDYDEEEEESSEA----GNQRLQQVMHAADPLE----IQADVHWTH 1044

Query: 790  IAPEIE-----PCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSLPLVRADD-- 842
            I    E     P +E+          + E D+ S  AE E    +   P       DD  
Sbjct: 1045 IREREEEERMAPASESSASGAPLDENDLEEDVDSEPAEIEGEAAEDGDPGDTGAELDDDQ 1104

Query: 843  -----PLRLDQELQQP---QTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQS 894
                 P   D+EL+ P   + + +    ++ED +   A     +    +   P     +S
Sbjct: 1105 HWSDSPSDADRELRLPCPAEGEAELELRVSEDEEKLPASPKHQERGPSQATSPIRSPQES 1164

Query: 895  FCESSSETPFHFTLPKEGDIIPPLTGAT 922
               +    P H +   EG  +PP+  AT
Sbjct: 1165 ---ALLFIPVH-SPSTEGPQLPPVPAAT 1188


>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 208/1008 (20%), Positives = 325/1008 (32%), Gaps = 169/1008 (16%)

Query: 184  NTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTAQPS 243
            N  P +VD E L+        + +S+ +   A   EE  NE+ P  ++   +I V    S
Sbjct: 763  NLRPVDVDPECLRWTPVIVSNSVVSEEEEEEA---EEGENEE-PQCQERELEISVGKSVS 818

Query: 244  KDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSPEP------ 297
               H  KEQ+     SE  P      V A  +  +LS Q L    L     P        
Sbjct: 819  ---HENKEQDSYSVESEKKP-----EVMAPVSSTRLSKQVLPHDSLPANSQPSRRGRWGR 870

Query: 298  EVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRS-LVQDSLS 356
            +   TQE   D+ +K +  +  S P  + G C                G++S   Q+  +
Sbjct: 871  KNRKTQERFGDKDSKLLLEETSSAPQEQYGEC----------------GEKSEATQEQYT 914

Query: 357  TNSSDLVA----PSPDAFRSTPFIVPSSPTEQEGRQDK--PMDTSVLSEEGGEPFQKKLQ 410
             +   LVA    PS D     P    S   E    Q K  P        EG E   ++  
Sbjct: 915  ESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKCRLTEGSERLPRRYS 974

Query: 411  SG---------EPVELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIF 461
             G         E  E E  P  P S+  P  + P  +    F      +  +   +  + 
Sbjct: 975  EGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRRRRVRKRKHHNSSVV 1034

Query: 462  IPSPS-----LEEQSNDGKKDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLM 516
              + S     L+E   D   +  M     T E  +  E E +N        L        
Sbjct: 1035 TETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENE-------LFPREYFRR 1087

Query: 517  LSTSEYSQSPKMESLSSHRIDEDGENTQIEDTEPMSPVL-----NSKFVPAENDSIL--- 568
            LS+ +  +        S   +ED E+   +DT  + PV      + K  P E D+     
Sbjct: 1088 LSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPLEPDTSTPLK 1147

Query: 569  -----------------MNPAQDGEVQLSQNDDKTKGDDTDTRDDISILATGCKGREETV 611
                               P +    +LS+               +SI   G K + +  
Sbjct: 1148 KKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKPKIQES 1207

Query: 612  AEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEVEEI-PET 670
             E V          + +P P  R E      + EEA    E   EE ++ SEV    P  
Sbjct: 1208 EETV-------EPKEDMPLPEERKEEEEMQAEAEEA----EEGEEEDAASSEVPAASPAD 1256

Query: 671  PCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSEAMEVETSVISIDSPQK 730
               S   E KE  +E       ++E Q Q    Q+E+ + E  E  +        D    
Sbjct: 1257 SSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDA 1316

Query: 731  LAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVS---CEPLEGVEKCSDSQSW 787
                D  LE  +++  EE  + +      DVKE  P V  S       +  EK  D +  
Sbjct: 1317 DDEDDGHLESTKKKELEEQPTRE------DVKE-EPGVQESFLDANMQKSREKIKDKEET 1369

Query: 788  EDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAET-----EPVEQDSSQPSLPLVRADD 842
            E  + E +P  +  + +++    E + +  S T E      E  E   S+  L  V+A  
Sbjct: 1370 ELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQ 1429

Query: 843  PLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSFCESSSET 902
             L  ++  +     +    +L     + +  Q   D +   +    A    S   S    
Sbjct: 1430 SLTQEESSEHEGAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHNSPISSVQSH 1489

Query: 903  PFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDVMSESMVE 962
            P           +P L        G+ ++ P++ S    +S      + TS +M    V 
Sbjct: 1490 PSQSVRSVSSPNVPALES------GYTQISPEQGS----LSAPSMQNMETSPMMDVPSVS 1539

Query: 963  THDP-ILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGERKNGSTA 1021
             H   ++ SG  D G                      S ES   N E P++ +   G + 
Sbjct: 1540 DHSQQVVDSGFSDLG----------------------SIESTTENYENPSSYDSTMGGSI 1577

Query: 1022 VAESVA---------SPQKTMSVLSCICEARQENEARS----EDPPTTPIRGNLLHFPSS 1068
               S +         S   +++  SC+   +  +   S    +     P     +  P S
Sbjct: 1578 CGNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQQSSVQPAANCSIKSPQS 1637

Query: 1069 QGEEEKEKLEGDHTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQ 1116
               E            Q QQP  P  P + P  P  Q      P  PQ
Sbjct: 1638 CVVERPPS-------NQQQQPPPP--PPQQPQPPPPQPQPAPQPPPPQ 1676



 Score = 58.2 bits (139), Expect = 8e-08
 Identities = 75/336 (22%), Positives = 129/336 (38%), Gaps = 40/336 (11%)

Query: 54   KENPVLDVVSNPEQTAGEERGDGNSGFNEHLKENKV--ADPVDSSNLDTCGSISQVIEQL 111
            KE+  L      E+    E  +   G  E    ++V  A P DSSN     +    +E+ 
Sbjct: 1214 KEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEE 1273

Query: 112  PQPNRTSSVLGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFG 171
             +  R S     S        EE+ +ELE+ E E+EED +  T  +   +D  +     G
Sbjct: 1274 EEKPRVSEEQRQS--------EEEQQELEEPEPEEEEDAAAETAQN---DDHDADDEDDG 1322

Query: 172  VLELSQSQDVEENTVPYEVD-----KEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDI 226
             LE ++ +++EE     +V      +E            ++ D +       EEQ + D 
Sbjct: 1323 HLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDT 1382

Query: 227  PIAEQ----SSKDIPVTAQPSKDVHVVKEQNPPPARSEDMPF-----------SPKASVA 271
             +  +    S  D    +   +++  +KE+   P    D+             S +   A
Sbjct: 1383 SVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGA 1442

Query: 272  AMEAKEQLSAQELMESGLQIQKSPEPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSL 331
              + +E L+A + ++S  Q  + P+   +S  ED     + +  S   S PS+     S 
Sbjct: 1443 YQDCEETLAACQTLQSYTQADEDPQ---MSMVEDCHASEHNSPISSVQSHPSQSVRSVSS 1499

Query: 332  ASTPATTLHLLQLSGQRSLVQDSLSTNSSDLVAPSP 367
             + PA      Q+S +    Q SLS  S   +  SP
Sbjct: 1500 PNVPALESGYTQISPE----QGSLSAPSMQNMETSP 1531



 Score = 55.1 bits (131), Expect = 7e-07
 Identities = 109/513 (21%), Positives = 190/513 (37%), Gaps = 79/513 (15%)

Query: 3    PTGSQLDSDFSQQ-DTPCLIIEDSQPESQVLEDDSGSHFSMLSRHLPNLQTHKENPVLDV 61
            P  S  DS  S + +T    +E+ + + +V E+   S         P  +  +E+   + 
Sbjct: 1250 PAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPE-EEEDAAAET 1308

Query: 62   VSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPNRTSSVL 121
              N +  A +E  DG      HL+  K         L+   +   V E+   P    S L
Sbjct: 1309 AQNDDHDADDE-DDG------HLESTK------KKELEEQPTREDVKEE---PGVQESFL 1352

Query: 122  GMSVE-SAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTAS--------------- 165
              +++ S   +++++  EL+ +E++   DTS  +    G+ED                  
Sbjct: 1353 DANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEE 1412

Query: 166  -----SQLGFGVLELSQSQDVEENTV---PYEVDKEQLQSVTTNSGYTRLSDVDANTAIK 217
                 S+L    ++  QS   EE++     Y+  +E L +  T   YT+ +D D   ++ 
Sbjct: 1413 EEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCEETLAACQTLQSYTQ-ADEDPQMSMV 1471

Query: 218  HEEQSNEDIPIAEQSSKDIPVTAQPSKDVHVVKEQNPPPARSEDMPFSPK------ASVA 271
                  ED   +E +S    V + PS+ V  V   N P   S     SP+       S+ 
Sbjct: 1472 ------EDCHASEHNSPISSVQSHPSQSVRSVSSPNVPALESGYTQISPEQGSLSAPSMQ 1525

Query: 272  AMEAKEQLSAQELMESGLQIQKSPEPE---VLSTQEDLFDQS--NKTVSSDGCSTPSREE 326
             ME    +    + +   Q+  S   +   + ST E+  + S  + T+    C   S  +
Sbjct: 1526 NMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENYENPSSYDSTMGGSICGN-SSSQ 1584

Query: 327  GGCS---LASTPATTLHLLQLSGQRSLVQDSLSTNSSDLVAPSPDAFRSTP--FIVPSSP 381
              CS   L+S+ + T     ++ Q + +  S S      V P+ +    +P   +V   P
Sbjct: 1585 SSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQQSSVQPAANCSIKSPQSCVVERPP 1644

Query: 382  TEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELENPPLLPESTVSPQASTPISQSTP 441
            + Q+ +   P            P Q +    +P     PP  P      Q   P  Q  P
Sbjct: 1645 SNQQQQPPPP-----------PPQQPQPPPPQPQPAPQPP--PPQQQPQQQPQPQPQQPP 1691

Query: 442  VFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDG 474
              PP     P      ++ F P+P + E    G
Sbjct: 1692 PPPPPQQQPPLSQCSMNNSFTPAPMIMEIPESG 1724



 Score = 36.6 bits (83), Expect = 0.25
 Identities = 67/348 (19%), Positives = 134/348 (38%), Gaps = 57/348 (16%)

Query: 994  PETEASEESLQFNLEKPATGERKNGSTAVAESVASPQKTMSVLSCICEARQENEARSEDP 1053
            P+ + SEE+++   + P   ERK      AE+  +            E  +E+ A SE P
Sbjct: 1202 PKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAE-----------EGEEEDAASSEVP 1250

Query: 1054 PTTPIRGNLLHFPSSQG-----EEEKEKLEGDHTIRQSQQPMKPISPVKDPVSPASQKMV 1108
              +P   +  + P ++      EEE+EK       RQS++  + +   ++P     +   
Sbjct: 1251 AASPADSS--NSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQEL---EEPEPEEEEDAA 1305

Query: 1109 IQGPSSPQGEAMVTDVLEDQKEG--RSTNKENPSKALIERPSQNNIGIQTMECSLRVPET 1166
             +   +   +A      +D+ +G   ST K    K L E+P++ ++  +       +   
Sbjct: 1306 AETAQNDDHDA------DDEDDGHLESTKK----KELEEQPTREDVKEEPGVQESFLDAN 1355

Query: 1167 VSAATQTIKNVCEQGTSTVDQNFGKQDATVQTERGSGEKPVSAPGDDTESLHSQGEEEFD 1226
            +  + + IK+  E    + ++      + V  +    E          E L    EEE  
Sbjct: 1356 MQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEE-- 1413

Query: 1227 MPQPPHGHVLHRHMRTIREVRTLVTRVITDVYYVDGTEVERKVTEETEEPIVECQECET- 1285
              + PH  +    + T++ V++L           + +       ++ EE +  CQ  ++ 
Sbjct: 1414 --EIPHSEL---DLETVQAVQSLTQ---------EESSEHEGAYQDCEETLAACQTLQSY 1459

Query: 1286 -------EVSPSQTGGSSGDLGDISSFSSKASSLHRTSSGTSLSAMHS 1326
                   ++S  +   +S     ISS  S  S   R+ S  ++ A+ S
Sbjct: 1460 TQADEDPQMSMVEDCHASEHNSPISSVQSHPSQSVRSVSSPNVPALES 1507


>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 208/1008 (20%), Positives = 325/1008 (32%), Gaps = 169/1008 (16%)

Query: 184  NTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTAQPS 243
            N  P +VD E L+        + +S+ +   A   EE  NE+ P  ++   +I V    S
Sbjct: 763  NLRPVDVDPECLRWTPVIVSNSVVSEEEEEEA---EEGENEE-PQCQERELEISVGKSVS 818

Query: 244  KDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSPEP------ 297
               H  KEQ+     SE  P      V A  +  +LS Q L    L     P        
Sbjct: 819  ---HENKEQDSYSVESEKKP-----EVMAPVSSTRLSKQVLPHDSLPANSQPSRRGRWGR 870

Query: 298  EVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRS-LVQDSLS 356
            +   TQE   D+ +K +  +  S P  + G C                G++S   Q+  +
Sbjct: 871  KNRKTQERFGDKDSKLLLEETSSAPQEQYGEC----------------GEKSEATQEQYT 914

Query: 357  TNSSDLVA----PSPDAFRSTPFIVPSSPTEQEGRQDK--PMDTSVLSEEGGEPFQKKLQ 410
             +   LVA    PS D     P    S   E    Q K  P        EG E   ++  
Sbjct: 915  ESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKCRLTEGSERLPRRYS 974

Query: 411  SG---------EPVELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIF 461
             G         E  E E  P  P S+  P  + P  +    F      +  +   +  + 
Sbjct: 975  EGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRRRRVRKRKHHNSSVV 1034

Query: 462  IPSPS-----LEEQSNDGKKDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLM 516
              + S     L+E   D   +  M     T E  +  E E +N        L        
Sbjct: 1035 TETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENE-------LFPREYFRR 1087

Query: 517  LSTSEYSQSPKMESLSSHRIDEDGENTQIEDTEPMSPVL-----NSKFVPAENDSIL--- 568
            LS+ +  +        S   +ED E+   +DT  + PV      + K  P E D+     
Sbjct: 1088 LSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPLEPDTSTPLK 1147

Query: 569  -----------------MNPAQDGEVQLSQNDDKTKGDDTDTRDDISILATGCKGREETV 611
                               P +    +LS+               +SI   G K + +  
Sbjct: 1148 KKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKPKIQES 1207

Query: 612  AEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEVEEI-PET 670
             E V          + +P P  R E      + EEA    E   EE ++ SEV    P  
Sbjct: 1208 EETV-------EPKEDMPLPEERKEEEEMQAEAEEA----EEGEEEDAASSEVPAASPAD 1256

Query: 671  PCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSEAMEVETSVISIDSPQK 730
               S   E KE  +E       ++E Q Q    Q+E+ + E  E  +        D    
Sbjct: 1257 SSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDA 1316

Query: 731  LAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVS---CEPLEGVEKCSDSQSW 787
                D  LE  +++  EE  + +      DVKE  P V  S       +  EK  D +  
Sbjct: 1317 DDEDDGHLESTKKKELEEQPTRE------DVKE-EPGVQESFLDANMQKSREKIKDKEET 1369

Query: 788  EDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAET-----EPVEQDSSQPSLPLVRADD 842
            E  + E +P  +  + +++    E + +  S T E      E  E   S+  L  V+A  
Sbjct: 1370 ELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQ 1429

Query: 843  PLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSFCESSSET 902
             L  ++  +     +    +L     + +  Q   D +   +    A    S   S    
Sbjct: 1430 SLTQEESSEHEGAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHNSPISSVQSH 1489

Query: 903  PFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDVMSESMVE 962
            P           +P L        G+ ++ P++ S    +S      + TS +M    V 
Sbjct: 1490 PSQSVRSVSSPNVPALES------GYTQISPEQGS----LSAPSMQNMETSPMMDVPSVS 1539

Query: 963  THDP-ILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGERKNGSTA 1021
             H   ++ SG  D G                      S ES   N E P++ +   G + 
Sbjct: 1540 DHSQQVVDSGFSDLG----------------------SIESTTENYENPSSYDSTMGGSI 1577

Query: 1022 VAESVA---------SPQKTMSVLSCICEARQENEARS----EDPPTTPIRGNLLHFPSS 1068
               S +         S   +++  SC+   +  +   S    +     P     +  P S
Sbjct: 1578 CGNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQQSSVQPAANCSIKSPQS 1637

Query: 1069 QGEEEKEKLEGDHTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQ 1116
               E            Q QQP  P  P + P  P  Q      P  PQ
Sbjct: 1638 CVVERPPS-------NQQQQPPPP--PPQQPQPPPPQPQPAPQPPPPQ 1676



 Score = 58.2 bits (139), Expect = 8e-08
 Identities = 75/336 (22%), Positives = 129/336 (38%), Gaps = 40/336 (11%)

Query: 54   KENPVLDVVSNPEQTAGEERGDGNSGFNEHLKENKV--ADPVDSSNLDTCGSISQVIEQL 111
            KE+  L      E+    E  +   G  E    ++V  A P DSSN     +    +E+ 
Sbjct: 1214 KEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEE 1273

Query: 112  PQPNRTSSVLGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFG 171
             +  R S     S        EE+ +ELE+ E E+EED +  T  +   +D  +     G
Sbjct: 1274 EEKPRVSEEQRQS--------EEEQQELEEPEPEEEEDAAAETAQN---DDHDADDEDDG 1322

Query: 172  VLELSQSQDVEENTVPYEVD-----KEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDI 226
             LE ++ +++EE     +V      +E            ++ D +       EEQ + D 
Sbjct: 1323 HLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDT 1382

Query: 227  PIAEQ----SSKDIPVTAQPSKDVHVVKEQNPPPARSEDMPF-----------SPKASVA 271
             +  +    S  D    +   +++  +KE+   P    D+             S +   A
Sbjct: 1383 SVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGA 1442

Query: 272  AMEAKEQLSAQELMESGLQIQKSPEPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSL 331
              + +E L+A + ++S  Q  + P+   +S  ED     + +  S   S PS+     S 
Sbjct: 1443 YQDCEETLAACQTLQSYTQADEDPQ---MSMVEDCHASEHNSPISSVQSHPSQSVRSVSS 1499

Query: 332  ASTPATTLHLLQLSGQRSLVQDSLSTNSSDLVAPSP 367
             + PA      Q+S +    Q SLS  S   +  SP
Sbjct: 1500 PNVPALESGYTQISPE----QGSLSAPSMQNMETSP 1531



 Score = 55.1 bits (131), Expect = 7e-07
 Identities = 109/513 (21%), Positives = 190/513 (37%), Gaps = 79/513 (15%)

Query: 3    PTGSQLDSDFSQQ-DTPCLIIEDSQPESQVLEDDSGSHFSMLSRHLPNLQTHKENPVLDV 61
            P  S  DS  S + +T    +E+ + + +V E+   S         P  +  +E+   + 
Sbjct: 1250 PAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPE-EEEDAAAET 1308

Query: 62   VSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPNRTSSVL 121
              N +  A +E  DG      HL+  K         L+   +   V E+   P    S L
Sbjct: 1309 AQNDDHDADDE-DDG------HLESTK------KKELEEQPTREDVKEE---PGVQESFL 1352

Query: 122  GMSVE-SAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTAS--------------- 165
              +++ S   +++++  EL+ +E++   DTS  +    G+ED                  
Sbjct: 1353 DANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEE 1412

Query: 166  -----SQLGFGVLELSQSQDVEENTV---PYEVDKEQLQSVTTNSGYTRLSDVDANTAIK 217
                 S+L    ++  QS   EE++     Y+  +E L +  T   YT+ +D D   ++ 
Sbjct: 1413 EEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCEETLAACQTLQSYTQ-ADEDPQMSMV 1471

Query: 218  HEEQSNEDIPIAEQSSKDIPVTAQPSKDVHVVKEQNPPPARSEDMPFSPK------ASVA 271
                  ED   +E +S    V + PS+ V  V   N P   S     SP+       S+ 
Sbjct: 1472 ------EDCHASEHNSPISSVQSHPSQSVRSVSSPNVPALESGYTQISPEQGSLSAPSMQ 1525

Query: 272  AMEAKEQLSAQELMESGLQIQKSPEPE---VLSTQEDLFDQS--NKTVSSDGCSTPSREE 326
             ME    +    + +   Q+  S   +   + ST E+  + S  + T+    C   S  +
Sbjct: 1526 NMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENYENPSSYDSTMGGSICGN-SSSQ 1584

Query: 327  GGCS---LASTPATTLHLLQLSGQRSLVQDSLSTNSSDLVAPSPDAFRSTP--FIVPSSP 381
              CS   L+S+ + T     ++ Q + +  S S      V P+ +    +P   +V   P
Sbjct: 1585 SSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQQSSVQPAANCSIKSPQSCVVERPP 1644

Query: 382  TEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELENPPLLPESTVSPQASTPISQSTP 441
            + Q+ +   P            P Q +    +P     PP  P      Q   P  Q  P
Sbjct: 1645 SNQQQQPPPP-----------PPQQPQPPPPQPQPAPQPP--PPQQQPQQQPQPQPQQPP 1691

Query: 442  VFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDG 474
              PP     P      ++ F P+P + E    G
Sbjct: 1692 PPPPPQQQPPLSQCSMNNSFTPAPMIMEIPESG 1724



 Score = 36.6 bits (83), Expect = 0.25
 Identities = 67/348 (19%), Positives = 134/348 (38%), Gaps = 57/348 (16%)

Query: 994  PETEASEESLQFNLEKPATGERKNGSTAVAESVASPQKTMSVLSCICEARQENEARSEDP 1053
            P+ + SEE+++   + P   ERK      AE+  +            E  +E+ A SE P
Sbjct: 1202 PKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAE-----------EGEEEDAASSEVP 1250

Query: 1054 PTTPIRGNLLHFPSSQG-----EEEKEKLEGDHTIRQSQQPMKPISPVKDPVSPASQKMV 1108
              +P   +  + P ++      EEE+EK       RQS++  + +   ++P     +   
Sbjct: 1251 AASPADSS--NSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQEL---EEPEPEEEEDAA 1305

Query: 1109 IQGPSSPQGEAMVTDVLEDQKEG--RSTNKENPSKALIERPSQNNIGIQTMECSLRVPET 1166
             +   +   +A      +D+ +G   ST K    K L E+P++ ++  +       +   
Sbjct: 1306 AETAQNDDHDA------DDEDDGHLESTKK----KELEEQPTREDVKEEPGVQESFLDAN 1355

Query: 1167 VSAATQTIKNVCEQGTSTVDQNFGKQDATVQTERGSGEKPVSAPGDDTESLHSQGEEEFD 1226
            +  + + IK+  E    + ++      + V  +    E          E L    EEE  
Sbjct: 1356 MQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEE-- 1413

Query: 1227 MPQPPHGHVLHRHMRTIREVRTLVTRVITDVYYVDGTEVERKVTEETEEPIVECQECET- 1285
              + PH  +    + T++ V++L           + +       ++ EE +  CQ  ++ 
Sbjct: 1414 --EIPHSEL---DLETVQAVQSLTQ---------EESSEHEGAYQDCEETLAACQTLQSY 1459

Query: 1286 -------EVSPSQTGGSSGDLGDISSFSSKASSLHRTSSGTSLSAMHS 1326
                   ++S  +   +S     ISS  S  S   R+ S  ++ A+ S
Sbjct: 1460 TQADEDPQMSMVEDCHASEHNSPISSVQSHPSQSVRSVSSPNVPALES 1507


>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 208/1008 (20%), Positives = 325/1008 (32%), Gaps = 169/1008 (16%)

Query: 184  NTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTAQPS 243
            N  P +VD E L+        + +S+ +   A   EE  NE+ P  ++   +I V    S
Sbjct: 763  NLRPVDVDPECLRWTPVIVSNSVVSEEEEEEA---EEGENEE-PQCQERELEISVGKSVS 818

Query: 244  KDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSPEP------ 297
               H  KEQ+     SE  P      V A  +  +LS Q L    L     P        
Sbjct: 819  ---HENKEQDSYSVESEKKP-----EVMAPVSSTRLSKQVLPHDSLPANSQPSRRGRWGR 870

Query: 298  EVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRS-LVQDSLS 356
            +   TQE   D+ +K +  +  S P  + G C                G++S   Q+  +
Sbjct: 871  KNRKTQERFGDKDSKLLLEETSSAPQEQYGEC----------------GEKSEATQEQYT 914

Query: 357  TNSSDLVA----PSPDAFRSTPFIVPSSPTEQEGRQDK--PMDTSVLSEEGGEPFQKKLQ 410
             +   LVA    PS D     P    S   E    Q K  P        EG E   ++  
Sbjct: 915  ESEEQLVASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKCRLTEGSERLPRRYS 974

Query: 411  SG---------EPVELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIF 461
             G         E  E E  P  P S+  P  + P  +    F      +  +   +  + 
Sbjct: 975  EGDRAVLRGFSESSEEEEEPESPRSSSPPILTKPTLKRKKPFLHRRRRVRKRKHHNSSVV 1034

Query: 462  IPSPS-----LEEQSNDGKKDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLM 516
              + S     L+E   D   +  M     T E  +  E E +N        L        
Sbjct: 1035 TETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENE-------LFPREYFRR 1087

Query: 517  LSTSEYSQSPKMESLSSHRIDEDGENTQIEDTEPMSPVL-----NSKFVPAENDSIL--- 568
            LS+ +  +        S   +ED E+   +DT  + PV      + K  P E D+     
Sbjct: 1088 LSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPLEPDTSTPLK 1147

Query: 569  -----------------MNPAQDGEVQLSQNDDKTKGDDTDTRDDISILATGCKGREETV 611
                               P +    +LS+               +SI   G K + +  
Sbjct: 1148 KKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVSTQACVIEPIVSIPKAGRKPKIQES 1207

Query: 612  AEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEVEEI-PET 670
             E V          + +P P  R E      + EEA    E   EE ++ SEV    P  
Sbjct: 1208 EETV-------EPKEDMPLPEERKEEEEMQAEAEEA----EEGEEEDAASSEVPAASPAD 1256

Query: 671  PCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSEAMEVETSVISIDSPQK 730
               S   E KE  +E       ++E Q Q    Q+E+ + E  E  +        D    
Sbjct: 1257 SSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDA 1316

Query: 731  LAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVS---CEPLEGVEKCSDSQSW 787
                D  LE  +++  EE  + +      DVKE  P V  S       +  EK  D +  
Sbjct: 1317 DDEDDGHLESTKKKELEEQPTRE------DVKE-EPGVQESFLDANMQKSREKIKDKEET 1369

Query: 788  EDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAET-----EPVEQDSSQPSLPLVRADD 842
            E  + E +P  +  + +++    E + +  S T E      E  E   S+  L  V+A  
Sbjct: 1370 ELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQ 1429

Query: 843  PLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSFCESSSET 902
             L  ++  +     +    +L     + +  Q   D +   +    A    S   S    
Sbjct: 1430 SLTQEESSEHEGAYQDCEETLAACQTLQSYTQADEDPQMSMVEDCHASEHNSPISSVQSH 1489

Query: 903  PFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDVMSESMVE 962
            P           +P L        G+ ++ P++ S    +S      + TS +M    V 
Sbjct: 1490 PSQSVRSVSSPNVPALES------GYTQISPEQGS----LSAPSMQNMETSPMMDVPSVS 1539

Query: 963  THDP-ILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGERKNGSTA 1021
             H   ++ SG  D G                      S ES   N E P++ +   G + 
Sbjct: 1540 DHSQQVVDSGFSDLG----------------------SIESTTENYENPSSYDSTMGGSI 1577

Query: 1022 VAESVA---------SPQKTMSVLSCICEARQENEARS----EDPPTTPIRGNLLHFPSS 1068
               S +         S   +++  SC+   +  +   S    +     P     +  P S
Sbjct: 1578 CGNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQQSSVQPAANCSIKSPQS 1637

Query: 1069 QGEEEKEKLEGDHTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQ 1116
               E            Q QQP  P  P + P  P  Q      P  PQ
Sbjct: 1638 CVVERPPS-------NQQQQPPPP--PPQQPQPPPPQPQPAPQPPPPQ 1676



 Score = 58.2 bits (139), Expect = 8e-08
 Identities = 75/336 (22%), Positives = 129/336 (38%), Gaps = 40/336 (11%)

Query: 54   KENPVLDVVSNPEQTAGEERGDGNSGFNEHLKENKV--ADPVDSSNLDTCGSISQVIEQL 111
            KE+  L      E+    E  +   G  E    ++V  A P DSSN     +    +E+ 
Sbjct: 1214 KEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEE 1273

Query: 112  PQPNRTSSVLGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFG 171
             +  R S     S        EE+ +ELE+ E E+EED +  T  +   +D  +     G
Sbjct: 1274 EEKPRVSEEQRQS--------EEEQQELEEPEPEEEEDAAAETAQN---DDHDADDEDDG 1322

Query: 172  VLELSQSQDVEENTVPYEVD-----KEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDI 226
             LE ++ +++EE     +V      +E            ++ D +       EEQ + D 
Sbjct: 1323 HLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDT 1382

Query: 227  PIAEQ----SSKDIPVTAQPSKDVHVVKEQNPPPARSEDMPF-----------SPKASVA 271
             +  +    S  D    +   +++  +KE+   P    D+             S +   A
Sbjct: 1383 SVVSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGA 1442

Query: 272  AMEAKEQLSAQELMESGLQIQKSPEPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSL 331
              + +E L+A + ++S  Q  + P+   +S  ED     + +  S   S PS+     S 
Sbjct: 1443 YQDCEETLAACQTLQSYTQADEDPQ---MSMVEDCHASEHNSPISSVQSHPSQSVRSVSS 1499

Query: 332  ASTPATTLHLLQLSGQRSLVQDSLSTNSSDLVAPSP 367
             + PA      Q+S +    Q SLS  S   +  SP
Sbjct: 1500 PNVPALESGYTQISPE----QGSLSAPSMQNMETSP 1531



 Score = 55.1 bits (131), Expect = 7e-07
 Identities = 109/513 (21%), Positives = 190/513 (37%), Gaps = 79/513 (15%)

Query: 3    PTGSQLDSDFSQQ-DTPCLIIEDSQPESQVLEDDSGSHFSMLSRHLPNLQTHKENPVLDV 61
            P  S  DS  S + +T    +E+ + + +V E+   S         P  +  +E+   + 
Sbjct: 1250 PAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPE-EEEDAAAET 1308

Query: 62   VSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPNRTSSVL 121
              N +  A +E  DG      HL+  K         L+   +   V E+   P    S L
Sbjct: 1309 AQNDDHDADDE-DDG------HLESTK------KKELEEQPTREDVKEE---PGVQESFL 1352

Query: 122  GMSVE-SAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTAS--------------- 165
              +++ S   +++++  EL+ +E++   DTS  +    G+ED                  
Sbjct: 1353 DANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEE 1412

Query: 166  -----SQLGFGVLELSQSQDVEENTV---PYEVDKEQLQSVTTNSGYTRLSDVDANTAIK 217
                 S+L    ++  QS   EE++     Y+  +E L +  T   YT+ +D D   ++ 
Sbjct: 1413 EEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCEETLAACQTLQSYTQ-ADEDPQMSMV 1471

Query: 218  HEEQSNEDIPIAEQSSKDIPVTAQPSKDVHVVKEQNPPPARSEDMPFSPK------ASVA 271
                  ED   +E +S    V + PS+ V  V   N P   S     SP+       S+ 
Sbjct: 1472 ------EDCHASEHNSPISSVQSHPSQSVRSVSSPNVPALESGYTQISPEQGSLSAPSMQ 1525

Query: 272  AMEAKEQLSAQELMESGLQIQKSPEPE---VLSTQEDLFDQS--NKTVSSDGCSTPSREE 326
             ME    +    + +   Q+  S   +   + ST E+  + S  + T+    C   S  +
Sbjct: 1526 NMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENYENPSSYDSTMGGSICGN-SSSQ 1584

Query: 327  GGCS---LASTPATTLHLLQLSGQRSLVQDSLSTNSSDLVAPSPDAFRSTP--FIVPSSP 381
              CS   L+S+ + T     ++ Q + +  S S      V P+ +    +P   +V   P
Sbjct: 1585 SSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQQSSVQPAANCSIKSPQSCVVERPP 1644

Query: 382  TEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELENPPLLPESTVSPQASTPISQSTP 441
            + Q+ +   P            P Q +    +P     PP  P      Q   P  Q  P
Sbjct: 1645 SNQQQQPPPP-----------PPQQPQPPPPQPQPAPQPP--PPQQQPQQQPQPQPQQPP 1691

Query: 442  VFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDG 474
              PP     P      ++ F P+P + E    G
Sbjct: 1692 PPPPPQQQPPLSQCSMNNSFTPAPMIMEIPESG 1724



 Score = 36.6 bits (83), Expect = 0.25
 Identities = 67/348 (19%), Positives = 134/348 (38%), Gaps = 57/348 (16%)

Query: 994  PETEASEESLQFNLEKPATGERKNGSTAVAESVASPQKTMSVLSCICEARQENEARSEDP 1053
            P+ + SEE+++   + P   ERK      AE+  +            E  +E+ A SE P
Sbjct: 1202 PKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAE-----------EGEEEDAASSEVP 1250

Query: 1054 PTTPIRGNLLHFPSSQG-----EEEKEKLEGDHTIRQSQQPMKPISPVKDPVSPASQKMV 1108
              +P   +  + P ++      EEE+EK       RQS++  + +   ++P     +   
Sbjct: 1251 AASPADSS--NSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQEL---EEPEPEEEEDAA 1305

Query: 1109 IQGPSSPQGEAMVTDVLEDQKEG--RSTNKENPSKALIERPSQNNIGIQTMECSLRVPET 1166
             +   +   +A      +D+ +G   ST K    K L E+P++ ++  +       +   
Sbjct: 1306 AETAQNDDHDA------DDEDDGHLESTKK----KELEEQPTREDVKEEPGVQESFLDAN 1355

Query: 1167 VSAATQTIKNVCEQGTSTVDQNFGKQDATVQTERGSGEKPVSAPGDDTESLHSQGEEEFD 1226
            +  + + IK+  E    + ++      + V  +    E          E L    EEE  
Sbjct: 1356 MQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIELKEEE-- 1413

Query: 1227 MPQPPHGHVLHRHMRTIREVRTLVTRVITDVYYVDGTEVERKVTEETEEPIVECQECET- 1285
              + PH  +    + T++ V++L           + +       ++ EE +  CQ  ++ 
Sbjct: 1414 --EIPHSEL---DLETVQAVQSLTQ---------EESSEHEGAYQDCEETLAACQTLQSY 1459

Query: 1286 -------EVSPSQTGGSSGDLGDISSFSSKASSLHRTSSGTSLSAMHS 1326
                   ++S  +   +S     ISS  S  S   R+ S  ++ A+ S
Sbjct: 1460 TQADEDPQMSMVEDCHASEHNSPISSVQSHPSQSVRSVSSPNVPALES 1507


>gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]
          Length = 3957

 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 223/1145 (19%), Positives = 417/1145 (36%), Gaps = 161/1145 (14%)

Query: 131  VEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQSQD----VEENTV 186
            VE+EKG  L Q+E +K E+ +      L    TA S+ G  V  +   ++     +E  +
Sbjct: 2029 VEKEKGPILTQREAQKTENQTIKRGQRLPVTGTAESKRGVRVSSIGVKKEDAAGGKEKVL 2088

Query: 187  PYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTAQPSKDV 246
             +++  E +QSV     + R S+V        +EQ + D+ I+       P     +   
Sbjct: 2089 SHKI-PEPVQSVPEEESH-RESEVPKEKMA--DEQGDMDLQIS-------PDRKTSTDFS 2137

Query: 247  HVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSPEPEVLSTQEDL 306
             V+K++     + +    S +   A +   + L++       L   K      LS Q   
Sbjct: 2138 EVIKQELEDNDKYQQFRLSEETEKAQLHLDQVLTSPFNTTFPLDYMKDEFLPALSLQSGA 2197

Query: 307  FDQSNKTVSSDGCS----------TP--SREEG--GCSLASTPATTLHLLQLSGQRSLVQ 352
             D S++++ ++G +          TP  S EE      LA TP T+   L  S ++S  Q
Sbjct: 2198 LDGSSESLKNEGVAGSPCGSLMEGTPQISSEESYKHEGLAETPETSPESLSFSPKKSEEQ 2257

Query: 353  DSLSTNSSDLVAPSPDAFRSTPFIVPSSPTEQE---GRQDKPMDTSVLSEEGGEPFQKKL 409
               +  S+     +    RS        PT ++   G +++    +  SE   E FQK+ 
Sbjct: 2258 TGETKESTK--TETTTEIRSE----KEHPTTKDITGGSEERGATVTEDSETSTESFQKEA 2311

Query: 410  QSGEPVELENPPLLPESTVSPQASTPISQSTPV-FPPGSLPIPSQPQFSHDIFIPSPSLE 468
              G P +  +P    + T S   S  +++ TP      +     Q  F           E
Sbjct: 2312 TLGSPKD-TSPKRQDDCTGS--CSVALAKETPTGLTEEAACDEGQRTFGSSAHKTQTDSE 2368

Query: 469  EQSNDGKKDGD--MHSSSLTVECSKTSEIEPK---NSPEDLGLSLTGDSCKLMLSTSEYS 523
             Q +    D    +     +V+    +E +P+    SP+ L L+L     +++ + ++ S
Sbjct: 2369 VQESTATSDETKALPLPEASVKTDTGTESKPQGVIRSPQGLELALPSRDSEVLSAVADDS 2428

Query: 524  ----------QSPKMESLSSHRIDEDGENTQIE--------DTEPMSPVLNSKFVP---- 561
                       SP +E  SSH+  +  E + ++        ++ P+ P + +   P    
Sbjct: 2429 LAVSHKDSLEASPVLEDNSSHKTPDSLEPSPLKESPCRDSLESSPVEPKMKAGIFPSHFP 2488

Query: 562  ---AENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDISILATGCK---GREETVAEDV 615
               A   + L+        +L ++ D +  D  D+ +  S++ +  K     +   +E+V
Sbjct: 2489 LPAAVAKTELLTEVASVRSRLLRDPDGSAED--DSLEQTSLMESSGKSPLSPDTPSSEEV 2546

Query: 616  CIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEVEEIPETPCESQ 675
              ++T  +   + P PA   E      D  E  E K   PEE       +       E +
Sbjct: 2547 SYEVTPKTTDVSTPKPAVIHECAEE--DDSENGEKKRFTPEEEMFKMVTKIKMFDELEQE 2604

Query: 676  GEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSEAMEVETSVISIDSPQKLAILD 735
             ++ ++   E      S +        +  + PK   S   E    V+     +K++   
Sbjct: 2605 AKQKRDYKKEPKQEESSSSSDPDADCSVDVDEPKHTGSGEDESGVPVLVTSESRKVS--- 2661

Query: 736  QELEHKEQEAWEEATSEDSSVV---IVDVKEPSP----------RVDVSCEPLEGVE--- 779
                  E E  +     DS ++   ++ V+ PSP            +V  +P+   +   
Sbjct: 2662 -SSSESEPELAQLKKGADSGLLPEPVIRVQPPSPLPSSMDSNSSPEEVQFQPVVSKQYTF 2720

Query: 780  KCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSL---- 835
            K ++    E    E E  +E+ L  ++  +V  E + +S     + + +D+ QP +    
Sbjct: 2721 KMNEDTQEEPGKSEEEKDSESHL-AEDRHAVSTEAEDRS----YDKLNRDTDQPKICDGH 2775

Query: 836  ---PLVRADDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHAS 892
                +  +     +   LQ P   +     +     +A       D E ++L    A + 
Sbjct: 2776 GCEAMSPSSSAAPVSSGLQSPTGDDVDEQPVIYKESLALQGTHEKDTEGEELDVSRAESP 2835

Query: 893  QSFCES---SSETPFHFTLPKEGDIIPPLTGATPPL--IGHLKLEPKRHSTPIGISNYPE 947
            Q+ C S   SS +     L  EG  +     AT  +      K +    + P    +   
Sbjct: 2836 QADCPSESFSSSSSLPHCLVSEGKELDEDISATSSIQKTEVTKTDETFENLPKDCPSQDS 2895

Query: 948  STIATSDVMSESMVETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNL 1007
            S    +D  S  +     P+    + D    P          ++ SP      +S  F+ 
Sbjct: 2896 SITTQTDRFSMDV-----PVSDLAENDEIYDP----------QITSPYENVPSQSF-FSS 2939

Query: 1008 EKPATGERKNGSTAVAES-VASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLLHFP 1066
            E+  T    N +T+   S V S   T  V   +  +       S++   +   G  +   
Sbjct: 2940 EESKTQTDANHTTSFHSSEVYSVTITSPVEDVVVASSSSGTVLSKE---SNFEGQDIKME 2996

Query: 1067 SSQGEEEKEKLEGDHTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVTDVLE 1126
            S Q E    +++ D ++  S +P   +S     V     K++I    +       +++ E
Sbjct: 2997 SQQ-ESTLWEMQSD-SVSSSFEP--TMSATTTVVGEQISKVII--TKTDVDSDSWSEIRE 3050

Query: 1127 DQKEGRSTNKENPSK---ALIERPSQNNIGIQTMECSLRVPETVSAATQTIKNVCEQGTS 1183
            D +   +  KE   K    +++R SQ              P+T  A T T     E+GT 
Sbjct: 3051 DDEAFEARVKEEEQKIFGLMVDRQSQGT-----------TPDTTPARTPT-----EEGTP 3094

Query: 1184 TVDQN 1188
            T +QN
Sbjct: 3095 TSEQN 3099


>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
          Length = 2400

 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 98/468 (20%), Positives = 170/468 (36%), Gaps = 52/468 (11%)

Query: 478  GDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHRID 537
            G  H  +L  E +   + +P  S    G+             +E    P+ E + +   +
Sbjct: 1807 GSGHEDNLQGEAAAGGDQDPGQSDGAEGIEAP---------EAEGEAQPESEGVEAPEAE 1857

Query: 538  EDGENT----QIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQL-SQNDDKTKGDDTD 592
             D +      Q E  +  +P    +  P   D  +  P  + EVQ  S+  +  + +   
Sbjct: 1858 GDAQEAEGEAQPESEDVEAPEAEGEAQPESED--VETPEAEWEVQPESEGAEAPEAEKEA 1915

Query: 593  TRDDISILATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEA----- 647
              +  S+ A   +G +E  +E        ++  +A       SE + S   +EEA     
Sbjct: 1916 QPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESE 1975

Query: 648  ----MEIK-EHHPEEGSSGSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLC 702
                +E++ E    EG +  E E++     E + +E +EE            + +S G+ 
Sbjct: 1976 DVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEE-----------AQPESDGV- 2023

Query: 703  LQKEMPKKECSEAMEVETSVISID---SPQKLAILDQELEHKEQEAWEEATSEDSSV--- 756
              +  PK E  EA EVE      +    P+   +   E E + QEA  E    +      
Sbjct: 2024 --EAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPE 2081

Query: 757  -VIVDVKEPSPRVDVSCEPLEGVEKCSDSQSWEDI-APEIEPCAENRLDTKEEKSVEYEG 814
               VD +E         E +E  E   ++Q  E I APE E  A+   +  E    E E 
Sbjct: 2082 SEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEA 2141

Query: 815  DLKSGTAETEPVEQDSSQPSLPLVRADDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQ 874
              +S   E +  E ++   S  +   +       EL+  +  E    +  E S+   A +
Sbjct: 2142 QPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPE-SEGIEAPE 2200

Query: 875  LSSDAEAQKLGKPSAHASQSFCESSSETPFHFTLPKEGDIIPPLTGAT 922
               +A+ +  G  +  A +   E+  E     T   EG+  P   G T
Sbjct: 2201 AEGEAQPELEGVEAPEAEE---EAQPEPEGVETPEAEGEAQPESEGET 2245



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 97/445 (21%), Positives = 153/445 (34%), Gaps = 64/445 (14%)

Query: 25   SQPESQVLEDDSGSHFSML-SRHLPNLQTHKENPVLDVVSNPE-------------QTAG 70
            +QPES+V+E       +   S  +  L+   E    +  + PE             Q A 
Sbjct: 1954 TQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAE 2013

Query: 71   EERGDGNSGFNEHLK-ENKVADPVDSSNLDTCGSISQVIE--QLPQPNRTSSVLGMSVES 127
            EE    + G     K E + A  V+     T G      +  + P+    +      V+ 
Sbjct: 2014 EEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQE 2073

Query: 128  APAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQSQDVEENTVP 187
            A      + E+++ +E E E         +  AE  A    G    E       E   + 
Sbjct: 2074 AEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGI- 2132

Query: 188  YEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTAQPSKDVH 247
             E  + + ++   + G      V+A  A    +  +E I   E   +     AQP     
Sbjct: 2133 -EAPEAEGEAQPESEG------VEAQDAEGEAQPESEGIEAQEAEEE-----AQPE---- 2176

Query: 248  VVKEQNPPPARSEDMPFSP--KASVAAMEAKEQLSAQELMESGLQIQKSPEPEVLSTQED 305
             ++    P A  E  P S   +A  A  EA+ +L   E  E+  + Q  PEPE + T E 
Sbjct: 2177 -LEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQ--PEPEGVETPEA 2233

Query: 306  LFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSLSTNSSDLVAP 365
               +      S+G  T   ++G      +P  +L      GQ     +S S    D   P
Sbjct: 2234 ---EGEAQPESEG-ETQGEKKG------SPQVSLG----DGQSEEASESSSPVPEDRPTP 2279

Query: 366  SPDAFRSTPFIVPSSPTEQEGRQ--------DKPMDTSVLSEEGGEPFQKKLQSGEP-VE 416
             P     TP   P S T     +         K  +   +  +   P  K   +G P  E
Sbjct: 2280 PPSPGGDTPHQRPGSQTGPSSSRASSWGNCWQKDSENDHVLGDTRSPDAKS--TGTPHAE 2337

Query: 417  LENPPLLPESTVSPQASTPISQSTP 441
             +   + PES+ S Q   P+   TP
Sbjct: 2338 RKATRMYPESSTSEQEEAPLGSRTP 2362



 Score = 40.8 bits (94), Expect = 0.013
 Identities = 156/754 (20%), Positives = 272/754 (36%), Gaps = 124/754 (16%)

Query: 582  NDDKTKGDDTDTRDDISILATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSV 641
            N+D+ + D  + R   ++        E TV E+V ++ T +          T  E L   
Sbjct: 1272 NEDEAERDSEEQRASSNLEQLA----ENTVQEEVQLEETKEG---------TEGEGL--- 1315

Query: 642  LDQEEAMEIKEHHPEEG--SSGSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQ 699
              QEEA++++E   EEG    G ++EE  ET  E +G++ +E  +E +       ET  +
Sbjct: 1316 --QEEAVQLEETKTEEGLQEEGVQLEETKET--EGEGQQEEEAQLEEI------EETGGE 1365

Query: 700  GLCLQKEMPKKECSEAMEVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIV 759
            GL  ++ +  +E  E  E      +++   K   L +E     QE   EA+S D      
Sbjct: 1366 GL-QEEGVQLEEVKEGPEGGLQGEALEEGLKEEGLPEEGSVHGQEL-SEASSPDGKGSQE 1423

Query: 760  D---VKEPSPRVDVSCE--PLEGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEG 814
            D    +E + R   S E  P EG E+ ++  S      E +P A  R    +  S    G
Sbjct: 1424 DDPVQEEEAGRASASAEPCPAEGTEEPTEPPSH---LSETDPSASER----QSGSQLEPG 1476

Query: 815  DLKSGTAETEPVEQDSSQPSLPLVRADDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQ 874
              K   A     E   +QP+         +     L             TE + +A+   
Sbjct: 1477 LEKPPGATMMGQEHTQAQPTQGAAERSSSVACSAALDCDPIWVSVLLKKTEKAFLAHLAS 1536

Query: 875  LSSDAEAQ-------KLGKPSAHASQSFC---ESSSETPFHFTLPKEGDII--PPLTGAT 922
              ++  A+        L + +A   Q      + S++        + G ++  PP    T
Sbjct: 1537 AVAELRARWGLQDNDLLDQMAAELQQDVAQRLQDSTKRELQKLQGRAGRMVLEPPREALT 1596

Query: 923  PPLIGHLKLEPKRHSTPIGISNYPESTIATSDVMSESMVETHDPILGSGKGDS-GAAPDV 981
              L+  L+ + +RH    G+ N    +  T  +   S     +P L +  G   G   + 
Sbjct: 1597 GELL--LQTQQRRHRLR-GLRNLSAFSERTLGLGPLSFTLEDEPALSTALGSQLGEEAEG 1653

Query: 982  DD----KLCLRMKL--VSPETE--ASEESLQFNLEKPATGERKNGSTAVAESV-ASPQKT 1032
            ++    + C+R K+  +SP+    A+   ++   +     +RK G     E+   +P KT
Sbjct: 1654 EEFCPCEACVRKKVSPMSPKATMGATRGPIKEAFDLQQILQRKRGEHTDGEAAEVAPGKT 1713

Query: 1033 MSVLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKEKLEGDHTIRQSQQPMKP 1092
             +              R+       +   L   P   G +E E  EG   + + + P   
Sbjct: 1714 HT---------DPTSTRTVQGAEGGLGPGLSQGP---GVDEGEDGEGSQRLNRDKDP--- 1758

Query: 1093 ISPVKDPVSPASQKMVIQGPSSPQGEAMVTDVLEDQKEGRSTNKENPSKALIERPSQNNI 1152
                                    GEA   D +  ++EG++ N E  + + +    Q   
Sbjct: 1759 ----------------------KLGEA-EGDAMAQEREGKTHNSETSAGSELGEAEQEGE 1795

Query: 1153 GIQTMECSLRVPETVSAATQTIKNVCEQGTSTVDQNFGKQDAT--VQTERGSGE-----K 1205
            GI          ET    +    N+  +  +  DQ+ G+ D    ++     GE     +
Sbjct: 1796 GISER------GETGGQGSGHEDNLQGEAAAGGDQDPGQSDGAEGIEAPEAEGEAQPESE 1849

Query: 1206 PVSAPGDDTESLHSQGE---EEFDMPQPPHGHVLHRHMRTIREVRTLVTRVITDVYYVDG 1262
             V AP  + ++  ++GE   E  D+  P            + E       V  +    + 
Sbjct: 1850 GVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDV-ETPEAEWEVQPESEGAEA 1908

Query: 1263 TEVERKVTEETEEPIVECQECETEVSPSQTGGSS 1296
             E E++   ETE   VE  E E E  P   G  +
Sbjct: 1909 PEAEKEAQPETES--VEALETEGEDEPESEGAEA 1940



 Score = 38.9 bits (89), Expect = 0.050
 Identities = 79/329 (24%), Positives = 107/329 (32%), Gaps = 87/329 (26%)

Query: 1231 PHGHVLHRHMRTIREVRTLVTRVITDVYYVDGTEVERKVTEETEEPIVECQECETEVSPS 1290
            P GH  H H R              D +    + ++  VT++   P    + C+    P 
Sbjct: 661  PRGHPRHSHYRK-------------DTH----SPLDSSVTKQVPRPPERRRACQDGSVPR 703

Query: 1291 QTGGSS-------GDLGDISSFSSKASSLHRTSSGTSLSAMHS----------------- 1326
             +G SS       G+L   SS S  +  L  TSS T   A+HS                 
Sbjct: 704  YSGSSSSTRTQASGNLRPPSSGSLPSQDLLGTSSATVTPAVHSDFVSGVSPHNAPSAGWA 763

Query: 1327 --SGSSGKGAGPLRGKTS-----------GTEPADFALPSS-------RGGPGKLSPRKG 1366
              +GS      P+   TS           G E  D   PSS       R   G + P + 
Sbjct: 764  GDAGSRTCSPAPIPPHTSDSCSKSGAASLGEEARDTPQPSSPLVLQVGRPEQGAVGPHRS 823

Query: 1367 --VSQTGTPVCEE---DGDAGLGIRQGGKAPVTPRGR---GRRGRPPSRTTGTRETAVPG 1418
               SQ GT   +E             G   P  PRGR    RR      T  + ++   G
Sbjct: 824  HCCSQPGTQPAQEAQRGPSPEASWLCGRYCPTPPRGRPCPQRRSSSCGSTGSSHQSTARG 883

Query: 1419 P-----LGIEDISPNLSPDDKSFSRVVPRVPDSTRRTDVGAGALRRSDSPEIPFQAAAGP 1473
            P      G     P  SP   S          ++RR+    GA  R  S E   ++  GP
Sbjct: 884  PGGSPQEGTRQPGPTPSPGPNS---------GASRRSSASQGAGSRGLSEEKTLRSGGGP 934

Query: 1474 SDGLDASSPGNSFVGL----RVVAKWSSN 1498
                +AS    S +       VV +W  N
Sbjct: 935  QGQEEASGVSPSSLPRSSPEAVVREWLDN 963



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 52/233 (22%), Positives = 88/233 (37%), Gaps = 39/233 (16%)

Query: 66   EQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPNRTSSVLGMSV 125
            E+ + E+R   N    E L EN V + V             + E+  Q   T +  G+  
Sbjct: 1277 ERDSEEQRASSNL---EQLAENTVQEEVQLEETKEGTEGEGLQEEAVQLEETKTEEGLQE 1333

Query: 126  ESAPAVE----EEKGEELEQKEKEKEEDTSGNTTHSLGA--EDTASSQLGFGVLELSQSQ 179
            E     E    E +G++ E+ + E+ E+T G      G   E+      G G+   +  +
Sbjct: 1334 EGVQLEETKETEGEGQQEEEAQLEEIEETGGEGLQEEGVQLEEVKEGPEG-GLQGEALEE 1392

Query: 180  DVEENTVPYE--VDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIP 237
             ++E  +P E  V  ++L   ++  G                + S ED P+ E+ +    
Sbjct: 1393 GLKEEGLPEEGSVHGQELSEASSPDG----------------KGSQEDDPVQEEEAGRAS 1436

Query: 238  VTAQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQ 290
             +A+P       +   PP   SE  P           A E+ S  +L E GL+
Sbjct: 1437 ASAEPCPAEGTEEPTEPPSHLSETDP----------SASERQSGSQL-EPGLE 1478



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 47/214 (21%), Positives = 74/214 (34%), Gaps = 29/214 (13%)

Query: 133  EEKGEELEQKEKEKEEDTSG---------NTTHSLGAEDTASSQLGFGV-------LELS 176
            E +G E  + EKE + +T           +   S GAE   + +             E+ 
Sbjct: 1902 ESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVI 1961

Query: 177  QSQDVEENTVPYEVDKEQLQ-----SVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQ 231
            +SQ+ EE   P   D E L+                 DV+A  A    +++ E     E 
Sbjct: 1962 ESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEE-----EA 2016

Query: 232  SSKDIPVTAQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQI 291
              +   V AQP  +    +E      ++E         V A EA+E+    E      + 
Sbjct: 2017 QPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEG 2076

Query: 292  QKSPEPEVLSTQEDLFDQSNKTVSSDGCSTPSRE 325
            +  PE E +  QE    +      S+G   P  E
Sbjct: 2077 EAHPESEDVDAQE---AEGEAQPESEGVEAPEAE 2107


>gi|87299628 biorientation of chromosomes in cell division 1-like
            [Homo sapiens]
          Length = 3051

 Score = 53.1 bits (126), Expect = 3e-06
 Identities = 280/1585 (17%), Positives = 538/1585 (33%), Gaps = 290/1585 (18%)

Query: 22   IEDSQPESQVLEDDSG--SHFSMLSRHLPNLQTHKENPVLDVVSNPEQTAGEERGDGNSG 79
            +E ++ +  +++ D    +  ++ S H  +L + +E+   +VV++     GE   D    
Sbjct: 386  VEGTKEDFSLIDSDVDGLTDITVSSVHTSDLSSFEEDTEEEVVTSDSMEEGEITSDDE-- 443

Query: 80   FNEHLKENKVADPVDSSNLDTCGSISQVIEQLP-------QPNRTSSVLGMSVESAPAVE 132
              E  K+NK       S+     S+       P         +     +    +S    +
Sbjct: 444  --EKNKQNKTKTQTSDSSEGKTKSVRHAYVHKPYLYSKYYSDSDDELTVEQRRQSIAKEK 501

Query: 133  EEK-------GEELEQKEKEKEEDTSGNTTHSLGA-----EDTASSQLGFGVLELSQ--- 177
            EE+        E+LE+K K+K E T  + T   G      E++++  L      + +   
Sbjct: 502  EERLLRRQINREKLEEKRKQKAEKTKSSKTKGQGRSSVDLEESSTKSLEPKAARIKEVLK 561

Query: 178  ------------------SQDVEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHE 219
                              S++VEEN+   +  +E  +     S +     + ++  +KH 
Sbjct: 562  ERKVLEKKVALSKKRKKDSRNVEENSKKKQQYEEDSKETLKTSEHCEKEKISSSKELKHV 621

Query: 220  EQSNEDIPIAEQSSKDIPVTAQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQL 279
               +E    A + S+ + V  +   +  + +E     +    M    +      + K Q+
Sbjct: 622  HAKSEPSKPARRLSESLHVVDENKNESKLEREHKRRTSTPVIME-GVQEETDTRDVKRQV 680

Query: 280  SAQELMESGLQIQKSP---------------------EPEVLSTQEDLFDQSNKTVSSDG 318
               E+     Q QKS                      + EV S++E    +  KT S D 
Sbjct: 681  ERSEICTEEPQKQKSTLKNEKHLKKDDSETPHLKSLLKKEVKSSKEK--PEREKTPSEDK 738

Query: 319  CSTPSREEGGCSLASTPATTLHLLQLSGQRSL-VQDSLSTNSSDLVAPSPDAFRSTPFIV 377
             S   + +G C   +   T LH    S ++ L V++++   S      S D         
Sbjct: 739  LSVKHKYKGDCMHKTGDETELH----SSEKGLKVEENIQKQSQQTKLSSDD--------- 785

Query: 378  PSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELENPP----LLPESTVSPQAS 433
                TE++ +       SVL ++G    +  +++ E V  EN      L  E T +   S
Sbjct: 786  ---KTERKSKHRNERKLSVLGKDGKPVSEYIIKTDENVRKENNKKERRLSAEKTKAEHKS 842

Query: 434  TPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGKKDGD-------------M 480
               S S        +   S     H I +   S  E  ++ K D D             +
Sbjct: 843  RRSSDS-------KIQKDSLGSKQHGITLQRRS--ESYSEDKCDMDSTNMDSNLKPEEVV 893

Query: 481  HSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPK--MESLSSHRIDE 538
            H      +     ++  K+  +  G  +     +L    ++ + +PK   E  +     E
Sbjct: 894  HKEKRRTKSLLEEKLVLKSKSKTQGKQVKVVETELQEGATKQATTPKPDKEKNTEENDSE 953

Query: 539  DGENTQIED-------TEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDT 591
                +++ED        EP+    +S     + DS     +   ++ L++   K+  D T
Sbjct: 954  KQRKSKVEDKPFEETGVEPVLETASSSAHSTQKDS-----SHRAKLPLAKEKYKSDKDST 1008

Query: 592  DTRDDISILATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEI- 650
             TR +   L+ G K R               S   +      + E  S   D ++  E+ 
Sbjct: 1009 STRLERK-LSDGHKSR---------------SLKHSSKDIKKKDENKS---DDKDGKEVD 1049

Query: 651  KEHHPEEGSSGSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKK 710
              H    G+S    +++    CE++   L +E  +      + T +   G  LQ+  PKK
Sbjct: 1050 SSHEKARGNSSLMEKKLSRRLCENRRGSLSQEMAKGEEKLAANTLSTPSGSSLQR--PKK 1107

Query: 711  ECSEAMEVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDV 770
                 +  E   + IDS       +  +E+  + +  +    ++S   +D +    +   
Sbjct: 1108 SGDMTLIPEQEPMEIDS-------EPGVENVFEVSKTQDNRNNNSQQDIDSENMKQKTSA 1160

Query: 771  SCEPLEGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDS 830
            + +  E     +DS++    AP  +P     +++  EK  ++   L         V + +
Sbjct: 1161 TVQKDELRTCTADSKA---TAPAYKPGRGTGVNSNSEKHADHRSTLTKKMHIQSAVSKMN 1217

Query: 831  SQPSLPLVRADDPLRLDQE------LQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKL 884
                 P+ R    + +D E      L  P   ++   +L    K   A++  +  +A   
Sbjct: 1218 PGEKEPIHRGTTEVNIDSETVHRMLLSAPSENDRVQKNL----KNTAAEEHVAQGDATLE 1273

Query: 885  GKPSAHASQSFCESSSETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHST-PIGIS 943
               +  +S S    SS T        + D+IP     T        LE    ST P   S
Sbjct: 1274 HSTNLDSSPSL---SSVTVVPLRESYDPDVIPLFDKRT-------VLEGSTASTSPADHS 1323

Query: 944  NYPESTIATSDVMSESMVETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASE--E 1001
              P  ++    V    +++T D    S +G  G   D   K  +  K   PE   +   +
Sbjct: 1324 ALPNQSLT---VRESEVLKTSD----SKEGGEGFTVDTPAKASITSKRHIPEAHQATLLD 1376

Query: 1002 SLQFNLEKPATGERKNGSTAVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGN 1061
              Q  +  P  G +  G     E++      + +      A++EN+  +E      I+  
Sbjct: 1377 GKQGKVIMP-LGSKLTGVIVENENITKEGGLVDM------AKKENDLNAEPNLKQTIKAT 1429

Query: 1062 LLHFPSSQGEEEKEKLEGDHTIRQSQQPMKPISPVKDPVSPASQKMVI------------ 1109
            +          +K+ +  DH +  + +       +K   SP   K +             
Sbjct: 1430 V-------ENGKKDGIAVDHVVGLNTEKYAETVKLKHKRSPGKVKDISIDVERRNENSEV 1482

Query: 1110 -------QGPS-----SPQGEAMVTDVLEDQKEGRSTNKENPSKALIERPSQ----NNIG 1153
                     PS     + Q E + T     +K   +T+ E   K +   P +        
Sbjct: 1483 DTSAGSGSAPSVLHQRNGQTEDVATGPRRAEKTSVATSTEGKDKDVTLSPVKAGPATTTS 1542

Query: 1154 IQTMECSLRVPET----------------------VSAATQTIKNVCEQGTSTVDQNFGK 1191
             +T +  + +P T                        A+  T+    E+G + V + F +
Sbjct: 1543 SETRQSEVALPCTSIEADEGLIIGTHSRNNPLHVGAEASECTVFAAAEEGGAVVTEGFAE 1602

Query: 1192 QDA--TVQTERGSGEKPVSAPGDDTESLHSQGEEEFDMPQPPHGHVLHRHMRTIREVRTL 1249
             +   T   E  SGE  V+   D    L                 +    ++    V ++
Sbjct: 1603 SETFLTSTKEGESGECAVAESEDRAADL-----------------LAVHAVKIEANVNSV 1645

Query: 1250 VTRVITDVYYVDGTEVE-----RKVTEETEEPIVECQECETE--VSPSQTGGSSGDLGDI 1302
            VT    D     G+E +      + +E  E  I    E E++  V+ + T   +G +   
Sbjct: 1646 VTEEKDDAVTSAGSEEKCDGSLSRDSEIVEGTITFISEVESDGAVTSAGTEIRAGSISSE 1705

Query: 1303 SSFSSKASSLHRTSSGTSLSAMHSSGSSGKGAGPLRGKTSGTEPADFALPSSRG---GPG 1359
                S+ + +       +   +  +G+ G+    +    +G  P +  + +  G   G  
Sbjct: 1706 EVDGSQGNMMRMGPKKETEGTVTCTGAEGRSDNFVICSVTGAGPREERMVTGAGVVLGDN 1765

Query: 1360 KLSPRKGVSQTGTPVCEEDGDAGLGIRQGGKAPVTPRGRGRRGRPPSRTTGTRETAVPGP 1419
               P    SQ        +GD  +     G++ VT  G    G  P+  TG+ +++    
Sbjct: 1766 DAPPGTSASQ--------EGDGSVNDGTEGESAVTSTGITEDGEGPASCTGSEDSSEGFA 1817

Query: 1420 LGIEDISPNLSPDDKSFSRVVPRVP 1444
            +  E      S  D + ++    VP
Sbjct: 1818 ISSESEENGESAMDSTVAKEGTNVP 1842



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 225/1210 (18%), Positives = 428/1210 (35%), Gaps = 184/1210 (15%)

Query: 134  EKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQSQDVEENTVPYEVDKE 193
            EKGE    ++KEK+E T     HS  +EDT   +      + ++ ++VE   +P E +  
Sbjct: 330  EKGE----RKKEKKEKTEKKFDHSKKSEDTQKVK----DEKQAKEKEVESLKLPSEKNSN 381

Query: 194  QLQSVT-TNSGYTRL-SDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTAQPSKDVHVVKE 251
            + ++V  T   ++ + SDVD  T I        D+   E+ +++  VT+   ++  +  +
Sbjct: 382  KAKTVEGTKEDFSLIDSDVDGLTDITVSSVHTSDLSSFEEDTEEEVVTSDSMEEGEITSD 441

Query: 252  ------QNPPPARSEDMP---------------------FSPKASVAAMEAKEQLSAQEL 284
                  QN    ++ D                       +S       +E + Q  A+E 
Sbjct: 442  DEEKNKQNKTKTQTSDSSEGKTKSVRHAYVHKPYLYSKYYSDSDDELTVEQRRQSIAKEK 501

Query: 285  MESGLQIQKSPEP-EVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQ 343
             E  L+ Q + E  E    Q+    +S+KT      S    E    SL    A    +L+
Sbjct: 502  EERLLRRQINREKLEEKRKQKAEKTKSSKTKGQGRSSVDLEESSTKSLEPKAARIKEVLK 561

Query: 344  ----------LSGQRSLVQDSLSTNSSDLVAPSPDAFRSTPFIVPSSPTEQEG-RQDKPM 392
                      LS +R     ++  NS        D   S   +  S   E+E     K +
Sbjct: 562  ERKVLEKKVALSKKRKKDSRNVEENSKKKQQYEED---SKETLKTSEHCEKEKISSSKEL 618

Query: 393  DTSVLSEEGGEPFQKKLQSGEPVELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPS 452
                   E  +P ++  +S   V+        E     + STP+          +  +  
Sbjct: 619  KHVHAKSEPSKPARRLSESLHVVDENKNESKLEREHKRRTSTPVIMEGVQEETDTRDVKR 678

Query: 453  QPQFSHDIFIPSP-----SLEEQSNDGKKDGDM-HSSSLTVECSKTSEIEP--KNSPEDL 504
            Q + S +I    P     +L+ + +  K D +  H  SL  +  K+S+ +P  + +P + 
Sbjct: 679  QVERS-EICTEEPQKQKSTLKNEKHLKKDDSETPHLKSLLKKEVKSSKEKPEREKTPSED 737

Query: 505  GLSL-----------TGDSCKLMLS---------------TSEYSQSPKMESLSSHRIDE 538
             LS+           TGD  +L  S                ++ S   K E  S HR +E
Sbjct: 738  KLSVKHKYKGDCMHKTGDETELHSSEKGLKVEENIQKQSQQTKLSSDDKTERKSKHR-NE 796

Query: 539  DGENTQIEDTEPMSPVLNSKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDIS 598
               +   +D +P+S  +         ++         E   +++  +   D    +D + 
Sbjct: 797  RKLSVLGKDGKPVSEYIIKTDENVRKENNKKERRLSAEKTKAEHKSRRSSDSKIQKDSLG 856

Query: 599  ILATG--CKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPE 656
                G   + R E+ +ED C   + +  S   P      E   +    EE + +K     
Sbjct: 857  SKQHGITLQRRSESYSEDKCDMDSTNMDSNLKPEEVVHKEKRRTKSLLEEKLVLKSKSKT 916

Query: 657  EGSSGSEVE-EIPE--TPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECS 713
            +G     VE E+ E  T   +  +  KE+N E         +++ Q     ++ P +E  
Sbjct: 917  QGKQVKVVETELQEGATKQATTPKPDKEKNTEE-------NDSEKQRKSKVEDKPFEETG 969

Query: 714  EAMEVETSVISIDSPQ-------KLAILDQE-----------LEHKEQEAWEEATSEDSS 755
                +ET+  S  S Q       KL +  ++           LE K  +  +  + + SS
Sbjct: 970  VEPVLETASSSAHSTQKDSSHRAKLPLAKEKYKSDKDSTSTRLERKLSDGHKSRSLKHSS 1029

Query: 756  VVIVDVKEPSPRVDVSCEPLEGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGD 815
              I    E         E     EK   + S  +       C ENR  +  ++  + E  
Sbjct: 1030 KDIKKKDENKSDDKDGKEVDSSHEKARGNSSLMEKKLSRRLC-ENRRGSLSQEMAKGEEK 1088

Query: 816  LKSGTAET---EPVEQDSSQPSLPLVRADDPLRLDQE------LQQPQTQEKTSNSLTED 866
            L + T  T     +++      + L+   +P+ +D E       +  +TQ+  +N+  +D
Sbjct: 1089 LAANTLSTPSGSSLQRPKKSGDMTLIPEQEPMEIDSEPGVENVFEVSKTQDNRNNNSQQD 1148

Query: 867  SKMANAKQLSS-------------DAEAQKLGKPSAHASQSFCESSSETPFHFTLPKEGD 913
                N KQ +S             D++A          +     S        TL K+  
Sbjct: 1149 IDSENMKQKTSATVQKDELRTCTADSKATAPAYKPGRGTGVNSNSEKHADHRSTLTKKMH 1208

Query: 914  IIPPLTGATPPLIGHLKLEP-KRHSTPIGISNYPESTIATSDVMSESMVETH------DP 966
            I   ++   P      + EP  R +T + I +     +  S       V+ +      + 
Sbjct: 1209 IQSAVSKMNPG-----EKEPIHRGTTEVNIDSETVHRMLLSAPSENDRVQKNLKNTAAEE 1263

Query: 967  ILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGERKNGSTAVAESV 1026
             +  G      + ++D    L    V P  E+ +  +    +K    E    ST+ A+  
Sbjct: 1264 HVAQGDATLEHSTNLDSSPSLSSVTVVPLRESYDPDVIPLFDKRTVLEGSTASTSPADHS 1323

Query: 1027 ASPQKTMSVLSC----ICEARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKEKLEGDHT 1082
            A P ++++V         ++++  E  + D P      +  H P +    +   L+G   
Sbjct: 1324 ALPNQSLTVRESEVLKTSDSKEGGEGFTVDTPAKASITSKRHIPEA---HQATLLDG--- 1377

Query: 1083 IRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVTDVLEDQKEGRSTNKENPSKA 1142
             +Q +  M        P+      ++++  +  +   +V    ++       N +   KA
Sbjct: 1378 -KQGKVIM--------PLGSKLTGVIVENENITKEGGLVDMAKKENDLNAEPNLKQTIKA 1428

Query: 1143 LIERPSQNNI------GIQTMECSLRVPETVSAATQTIKNVCEQGTSTVDQNFGKQDATV 1196
             +E   ++ I      G+ T + +  V      +   +K++      ++D     +++ V
Sbjct: 1429 TVENGKKDGIAVDHVVGLNTEKYAETVKLKHKRSPGKVKDI------SIDVERRNENSEV 1482

Query: 1197 QTERGSGEKP 1206
             T  GSG  P
Sbjct: 1483 DTSAGSGSAP 1492



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 254/1269 (20%), Positives = 451/1269 (35%), Gaps = 278/1269 (21%)

Query: 122  GMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQSQ-D 180
            G+   +    E+E+GE++        E    +T   LG E         GVL    ++ D
Sbjct: 1853 GIVTSTGAKEEDEEGEDVVTSTGRGNEIGHASTCTGLGEESE-------GVLICESAEGD 1905

Query: 181  VEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTA 240
             +  TV   V+ E   ++   +     ++VD+ +     E+ ++D  I   S+K I V +
Sbjct: 1906 SQIGTVVEHVEAEAGAAIMNANE----NNVDSMSGT---EKGSKDTDICS-SAKGI-VES 1956

Query: 241  QPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQE--LMESGL--------- 289
              +  V    E  P P   E     P  S A+ ++  QL   E   + +GL         
Sbjct: 1957 SVTSAVSGKDEVTPVPGGCE----GPMTSAASDQSDSQLEKVEDTTISTGLVGGSYDVLV 2012

Query: 290  -------------QIQKSPEPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCS-----L 331
                           +K  E  + S + +  D    T +S   +  +   GG +     +
Sbjct: 2013 SGEVPECEVAHTSPSEKEDEDIITSVENEECDGLMATTASGDITNQNSLAGGKNQGKVLI 2072

Query: 332  ASTPATTLHLLQLSGQRSL---VQDSLSTNSS---------DLVAPSPDAFRSTPFIVPS 379
             ST  T  +  Q+S    +   + D+L T  +         +  AP P A       + +
Sbjct: 2073 ISTSTTNDYTPQVSAITDVEGGLSDALRTEENMEGTRVTTEEFEAPMPSAVSGDDSQLTA 2132

Query: 380  SPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELENPPLLPESTVSPQASTPISQS 439
            S +E++       + +++S   GE F+  + S   ++         + V  +A+ P+  S
Sbjct: 2133 SRSEEKD------ECAMISTSIGEEFELPISSATTIKCAESLQPVAAAVEERATGPVLIS 2186

Query: 440  TPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGKKDGDMHSSSLTVEC-SKTSEIEPK 498
            T  F     P+PS P  +      SP L   S + K +  + S+S+  EC +  S +  +
Sbjct: 2187 TADFEG---PMPSAPPEAE-----SP-LASTSKEEKDECALISTSIAEECEASVSGVVVE 2237

Query: 499  NSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHRIDEDGENTQIEDTEPMSPVLNSK 558
            +  E  G  +       ++STS                        +ED E   PV  S 
Sbjct: 2238 SENERAGTVMEEKDGSGIISTSS-----------------------VEDCE--GPV--SS 2270

Query: 559  FVPAENDSILMNPAQD-GEVQLSQNDDKTKGDDTDTRDDISILATGCKGREETVAEDVCI 617
             VP E     + PA++ G+  +           T T +    +  G   ++E   + + I
Sbjct: 2271 AVPQEEGDPSVTPAEEMGDTAMIS---------TSTSEGCEAVMIGAVLQDE---DRLTI 2318

Query: 618  DLTCDSGSQAVPSPATRS-EALSSVLDQEEAMEIKEHHPEEGS--SGSEVEE-------- 666
                D    A+ S +T     +S+ +D+ E  ++   +PE     S +EV +        
Sbjct: 2319 TRVEDLSDAAIISTSTAECMPISASIDRHEENQLTADNPEGNGDLSATEVSKHKVPMPSL 2378

Query: 667  IPETPCESQGEEL------------KEENMESVPLHL-SLTETQSQGLCLQKEMPK-KEC 712
            I E  C   G                EE      +H  S  +     +C +KE    KEC
Sbjct: 2379 IAENNCRCPGPVRGGKEPGPVLAVSTEEGHNGPSVHKPSAGQGHPSAVCAEKEEKHGKEC 2438

Query: 713  SEAM------EVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSP 766
             E        + E+++  I++ +K  +L+     KE ++ E  T+  SS           
Sbjct: 2439 PEIGPFAGRGQKESTLHLINAEEKNVLLNSL--QKEDKSPETGTAGGSSTASYSAGRGLE 2496

Query: 767  RVDVSCEPLEGVEKCSDSQSWE-------------------DIAPEIEPCAENRLDTKEE 807
                S   L G E+ S   + +                   D+ P     AE+     E+
Sbjct: 2497 GNANSPAHLRGPEQTSGQTAKDPSVSIRYLAAVNTGAIKADDMPPVQGTVAEHSFLPAEQ 2556

Query: 808  KSVEYEGDLKSGTAETEPVEQDSSQPSLPLVRADDPLRLDQELQQPQTQEKTSNSLTEDS 867
            +  E   +LK+ T +    ++    PS  ++    P      L  P+ ++  +       
Sbjct: 2557 QGSE--DNLKTSTTKCITGQESKIAPSHTMI---PPATYSVALLAPKCEQDLTIKNDYSG 2611

Query: 868  K---MANAKQLSSDAEAQKLGKP------SAHASQSFCE-SSSETPFHFT---------- 907
            K    A+A++   D   +K          +  + ++ C+  + E+P +            
Sbjct: 2612 KWTDQASAEKTGDDNSTRKSFPEEGDIMVTVSSEENVCDIGNEESPLNVLGGLKLKANLK 2671

Query: 908  ----LPKE----GDIIPP---LTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSDVM 956
                +P E    G+I+ P   L G  P  I  L+ EP   +  + + N    T    ++ 
Sbjct: 2672 MEAYVPSEEEKNGEILAPPESLCGGKPSGIAELQREPLLVNESLNVENSGFRT--NEEIH 2729

Query: 957  SESMVETHDPILGSGKGD-----SGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPA 1011
            SES  +     + SG+ D     SG + + D K     +   P+ +  +  L       +
Sbjct: 2730 SESYNKGE---ISSGRKDNAEAISGHSVEADPKEVEEEERHMPKRKRKQHYL-------S 2779

Query: 1012 TGERKNGSTAVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLL-------- 1063
            + +  + +  V +S     +     +   + ++EN    E+ P T    N          
Sbjct: 2780 SEDEPDDNPDVLDSRIETAQRQCPETEPHDTKEENSRDLEELPKTSSETNSTTSRVMEEK 2839

Query: 1064 -HFPSSQGEEEKEKLEGDHTIRQSQQPMKPI-------SPVKDPVSPASQKM-------- 1107
              + SS+   EK +   D TI+ SQ+  +PI        P K PV    +          
Sbjct: 2840 DEYSSSETTGEKPEQNDDDTIK-SQEEDQPIIIKRKRGRPRKYPVETTLKMKDDSKTDTG 2898

Query: 1108 ---VIQGPSSPQGEAMVTDVLEDQKEGRSTNKENPSKALIERPSQNNIGIQTMECSLRVP 1164
               V Q PSS + + M TD          +NKE  +  L ER   N+ G + +  S+R  
Sbjct: 2899 IVTVEQSPSSSKLKVMQTD---------ESNKETAN--LQERSISNDDGEEKIVTSVRRR 2947

Query: 1165 ETVSAATQTIKNVCEQGTSTVDQNFGKQDATVQTERGSGEKPVSAPGDDTESLHSQGEEE 1224
                  + T+ +                DA         +K VS P +D +   S  EEE
Sbjct: 2948 GRKPKRSLTVSD----------------DAESSEPERKRQKSVSDPVEDKKEQESDEEEE 2991

Query: 1225 FDMPQPPHG 1233
             +    P G
Sbjct: 2992 EEEEDEPSG 3000


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 53.1 bits (126), Expect = 3e-06
 Identities = 189/940 (20%), Positives = 318/940 (33%), Gaps = 169/940 (17%)

Query: 227  PIAEQSSKDIPVTAQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELME 286
            P  +Q SK     +  S   H   +   PP +          S+ + +A EQ    +   
Sbjct: 821  PPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQG---------SITSPQANEQSVTPQRRS 871

Query: 287  SGLQIQKSPEPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLA-------------- 332
                 + SP+PE+ S        S  +      STP R+    S +              
Sbjct: 872  C---FESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQR 928

Query: 333  -----STPATTLHLLQLSGQRSLVQDSLSTNSSDLVAPSPDAFRSTPF--IVPSSPTEQE 385
                 S+P+ +    + + +RS      S   S L+     +  S+P   + P +P  Q 
Sbjct: 929  SHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQS 988

Query: 386  GRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELENPPLLPESTVSPQASTPISQSTP---- 441
                      V ++    P     +S  P E     L+     S      +  STP    
Sbjct: 989  HSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGES 1048

Query: 442  VFPPGSLPIPSQPQFSHD------------IFIPSPSLEEQSNDGKKDGDMHSSSLTVEC 489
             F   SL +  Q Q S D                SPSL+ +S    K G   SSS   E 
Sbjct: 1049 YFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTEL 1108

Query: 490  SKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMES-LSSHRIDEDGENTQIEDT 548
            +  S I      +D G               E+S SP ++S +S  +     +++     
Sbjct: 1109 ASRSPIR-----QDRG---------------EFSASPMLKSGMSPEQSRFQSDSSSYPTV 1148

Query: 549  EPMSPVLNSKFVPAEN-DSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDISILATGCKGR 607
            +  S +  S+   AE+ + + + P +D      +  DK        R + S++    K  
Sbjct: 1149 DSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLV---FKDT 1205

Query: 608  EETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEGSS-----GS 662
              T   +        SG+ + P    ++ AL +    EE ME+ E   E          S
Sbjct: 1206 LRTPPRE-------RSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSS 1258

Query: 663  EVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECS--------E 714
            E++E+  +  ES       E  E   + L+L ++QSQ      E+P    S        E
Sbjct: 1259 ELKEMSTSNFES-----SPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPE 1313

Query: 715  AMEVETSVI---SIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVS 771
              E+  S +   S  SP +       L  +    +     ED +   ++  E  P +D+ 
Sbjct: 1314 HKELSNSPLRENSFGSPLEFR-NSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDM- 1371

Query: 772  CEPLEGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSS 831
                    K   ++S    + E+ P A  +      +S+     +      T   E+ SS
Sbjct: 1372 --------KEQSTRSSGHSSSELSPDAVEKAGMSSNQSI--SSPVLDAVPRTPSRERSSS 1421

Query: 832  QPSLPLVRADDPLRLDQELQQPQTQEKTSNS--LTEDSKMANAKQLSSDAEAQKLGKPSA 889
                    A  P   D   + P  + ++ +S  L + S   +   LS  +   K    + 
Sbjct: 1422 --------ASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTP 1473

Query: 890  HASQSFCESSSETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRH------------- 936
               +S C+SS E       P+     P     + P + +  L P+R              
Sbjct: 1474 SRGRSECDSSPEPKALPQTPR-----PRSRSPSSPELNNKCLTPQRERSGSESSVDQKTV 1528

Query: 937  -STPIGISNYPEST-------------IATSDVMSESMVETHDPILGSGKGDSGAAPDVD 982
              TP+G  +   S+              + SD   +S  +T  P+    +  SG++P+VD
Sbjct: 1529 ARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPL--RQRSRSGSSPEVD 1586

Query: 983  DKLCLRMKLVSPETEASEESLQFNLEKPATGERKNGSTAVAESVAS-----PQKTMSVLS 1037
             K       +SP    S  S +   +  A    ++GS +  E  A      P+++ S  S
Sbjct: 1587 SK-----SRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSS 1641

Query: 1038 CICEA-RQENEARSEDPPTTPIRGNLLHFPSSQGEEEKEK 1076
                    E  + +E  P  P +       S    E K K
Sbjct: 1642 SKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTK 1681



 Score = 40.0 bits (92), Expect = 0.023
 Identities = 34/125 (27%), Positives = 54/125 (43%), Gaps = 7/125 (5%)

Query: 365 PSPDAFRSTPFIVPSSPT----EQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELENP 420
           PSP   RS+    P +PT    E+ G   +P+ T+ LS+E   P  +   + +    ++P
Sbjct: 350 PSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSP 409

Query: 421 PLLPESTVS---PQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGKKD 477
             LP+S+ S   P +  P   S         P P+    SH     SP+ + +S+   K 
Sbjct: 410 EKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKR 469

Query: 478 GDMHS 482
              HS
Sbjct: 470 DKSHS 474



 Score = 36.2 bits (82), Expect = 0.33
 Identities = 34/106 (32%), Positives = 51/106 (48%), Gaps = 12/106 (11%)

Query: 1626 KRKRRSNVSSPATPTASSSSSTTPTRKITESPRASMGVLSGKRKLITSEEERSPAKRG-- 1683
            KRKRRS+ SS ++ ++SSSSS++ +   + S  +S    S      +S    SPAK G  
Sbjct: 2602 KRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS----SSSSSSSSSSSSPSPAKPGPQ 2657

Query: 1684 --RKSATVKPGAVGAGEFVSPCESGDNTGEPSALE----EQRGPLP 1723
               K A+ K    G     SP +  D+  +  +L     E+R P P
Sbjct: 2658 ALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSP 2703



 Score = 35.8 bits (81), Expect = 0.43
 Identities = 69/346 (19%), Positives = 131/346 (37%), Gaps = 32/346 (9%)

Query: 818  SGTAETEPVEQDSSQPSLPLVRADDPLRLDQELQQPQTQEKTSNS------LTEDSKMAN 871
            S  +++    + +  PS  + +A     L     QP++   ++ S      + + + +A 
Sbjct: 2412 SAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAG 2471

Query: 872  AKQLSSDAEAQKLGKPSAHASQSFCESSSETPFHFTLPKEGDIIPPLTGATPP-LIGHLK 930
            ++ LSS A A        H       +          P      P  TGA  P  +  L+
Sbjct: 2472 SQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEP------PASTGAQQPSALAALQ 2525

Query: 931  LEPKRHSTPIGISNYPESTIATSDVMSESMVETHDPILGSGKGDS-GAAPDVDDKLCLRM 989
               +R S+    S+   S+ ++S   S S         GS   DS G++  V  ++ L+ 
Sbjct: 2526 PAKERRSSSSSSSSSSSSSSSSSSSSSSSSS-------GSSSSDSEGSSLPVQPEVALK- 2577

Query: 990  KLVSPETEASEESLQFNLEKPATGERKNGSTAVAESVASPQKTMSVLSCICEARQENEAR 1049
            ++ SP     E   +    +P   +RK  S++ + S +S   + S  S    +   + + 
Sbjct: 2578 RVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2637

Query: 1050 SEDPPTTPIRGNLLHFPSSQG----EEEKEKLEGDHTIRQSQQPMKPISPVKDPVSPASQ 1105
            S    ++         P  Q        K+   G+   R+S+ P KPI  ++D  S +  
Sbjct: 2638 SSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGE---RRSRSPRKPIDSLRDSRSLSYS 2694

Query: 1106 KMVIQGPS---SPQGEAMVTDVLEDQKEGRSTNKENPSKALIERPS 1148
             +  + PS   SP+ +   +     ++  R  ++    K   E PS
Sbjct: 2695 PVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPS 2740



 Score = 33.9 bits (76), Expect = 1.6
 Identities = 92/437 (21%), Positives = 148/437 (33%), Gaps = 66/437 (15%)

Query: 73  RGDGNSGF---NEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPNRTSSVLGMSVESAP 129
           RG G +G+   N  L   +  +  D    +    +   + + P P+         VE   
Sbjct: 11  RGSGTNGYVQRNLSLVRGRRGERPDYKGEEELRRLEAALVKRPNPDILDHERKRRVELRC 70

Query: 130 AVEEEKGEELEQKEKEKEEDTSGNTTHSL-------GAEDTASSQLGFGVLELSQSQDVE 182
              EE  EE   +E++ +E  +      L       G E+T   +    V E  Q  ++ 
Sbjct: 71  LELEEMMEEQGYEEQQIQEKVATFRLMLLEKDVNPGGKEETPGQRPA--VTETHQLAELN 128

Query: 183 ENTVPYEVDKEQLQSVT-TNSGYTRLSDVDANTAIKHEEQSNEDIP-----IAEQSSKDI 236
           E         E+L++    +  Y   S  D     +  +Q   + P     + E SS   
Sbjct: 129 EKK------NERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRS 182

Query: 237 PVTAQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSPE 296
           P   Q  K     K++     RSE    SP+        K++  ++   ES  +  +SP 
Sbjct: 183 PTPKQKKK-----KKKKDRGRRSESS--SPRRERKKSSKKKKHRSES--ESKKRKHRSPT 233

Query: 297 PEVLSTQEDLFDQSNKTVS----------SDGCSTPSREEGGCSLASTPATTLHLLQLSG 346
           P+     +D   + +++ +          S    + S  +   S + + A   H   L+G
Sbjct: 234 PKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAG 293

Query: 347 QRSLVQDSLSTNSSDLVAPSPDAFRS-------TPFIVPSSPTEQEGRQDK------PMD 393
            RS    S      D     P    +       T    PSSP E + +  K      P  
Sbjct: 294 -RSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSP 352

Query: 394 TSVLSEEGGEP-----FQKKLQSGEPVELENPPLLPESTVSPQASTPISQSTPVFPPGSL 448
           +   S  G EP        +   G P  L   PL  E    P  ++P    +P   P  L
Sbjct: 353 SPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKL 412

Query: 449 PIPSQPQFSHDIFIPSP 465
           P  S  + S     PSP
Sbjct: 413 PQSSSSESSP----PSP 425



 Score = 31.6 bits (70), Expect = 8.0
 Identities = 49/202 (24%), Positives = 76/202 (37%), Gaps = 23/202 (11%)

Query: 1303 SSFSSKASSLHRTSSGTSLSAMHSSGSSGKGAGPLRGKTSGTEP--ADFALPS------- 1353
            SS SS +SS   +SS +S S+  SS SSG  +    G +   +P  A   +PS       
Sbjct: 2532 SSSSSSSSS---SSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKE 2588

Query: 1354 --SRGGPGKLSPRKGVSQTGTPVCEEDGDAGLGIRQGGKAPVTPRGRGRRGRPPSRTTGT 1411
                G P + +P K   ++ +        +         +  +           S ++ +
Sbjct: 2589 AVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2648

Query: 1412 RETAVPGPLGI-EDISPNLSPDDKSFSRVVPRVPDSTR--RTDVGAGALRRSDSPEIPFQ 1468
               A PGP  + +  SP   P  +  SR   +  DS R  R+   +   RR  SP+    
Sbjct: 2649 PSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQ---- 2704

Query: 1469 AAAGPSDGLDASSPGNSFVGLR 1490
                P D   +SS   S  G R
Sbjct: 2705 --PSPRDQQSSSSERGSRRGQR 2724


>gi|62241003 cardiomyopathy associated 5 [Homo sapiens]
          Length = 4069

 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 201/967 (20%), Positives = 341/967 (35%), Gaps = 166/967 (17%)

Query: 354  SLSTNSSDLVAPSPDAF---RSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQ 410
            SL   S  L A + D     +  P +      E    +  P   SV  E+     +  + 
Sbjct: 435  SLEAASPGLAASTQDGLDPDQEQPDLTSIERAEPVSAKLTPTHPSVKGEKEENMLEPSIS 494

Query: 411  SGEPVELENPPLLPESTVSPQASTPISQSTPVFPPG--SLPIPSQPQFSHDIFIPSPSLE 468
              EP+ LE P      T  P A TP  + + +       L  P  P  S   F P  S E
Sbjct: 495  LSEPLMLEEPEKEEIETSLPIAITPEPEDSNLVEEEIVELDYPESPLVSEKPFPPHMSPE 554

Query: 469  EQSNDGKKDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGD-------SCKLMLSTSE 521
             +  + +    + ++S     + + E   + +    G +   +       + +L     E
Sbjct: 555  VEHKEEELILPLLAASSPEHVALSEEEREEIASVSTGSAFVSEYSVPQDLNHELQEQEGE 614

Query: 522  YSQSPKMESLSSHRIDEDGENTQIEDTEP-MSPVLNSKFVP------AENDSILMNPAQD 574
                  +E+++ H +  + EN + E   P  +P   S   P      +EN S L +    
Sbjct: 615  PVPPSNVEAIAEHAVLSEEENEEFEAYSPAAAPTSESSLSPSTTEKTSENQSPLFSTVTP 674

Query: 575  GEVQLSQNDDKTKGDDTDTRDDISILATGCKGREETVAEDVCIDLTCDSGSQAVPSPATR 634
              + LS       GD+           +GC   + T A +            +VPS AT+
Sbjct: 675  EYMVLS-------GDEAS--------ESGCYTPDSTSASE-----------YSVPSLATK 708

Query: 635  SEALSSVLDQEEAMEIKEHHPEEGSSGSEVEEIPETPCESQGEELKEENMESVPLHLSLT 694
             E+L   +D++  + +K         G     IP    E  G         S P  LS +
Sbjct: 709  -ESLKKTIDRKSPLILK---------GVSEYMIPSEEKEDTGSFTPAVAPASEP-SLSPS 757

Query: 695  ETQSQGLCLQKEMPKKECSEAM------EVETSVISIDSP--QKLAILDQELEHKEQEAW 746
             T+    C Q  +P    SE +      ++ +   + DS    K A      +  +++  
Sbjct: 758  TTEKTSEC-QSPLPSTATSEHVVPSEGEDLGSERFTPDSKLISKYAAPLNATQESQKKII 816

Query: 747  EEATS------EDSSVVIVDVKE----PSPRVDVSCE---PLEGVEKCSDSQSWEDIAPE 793
             EA+        + +V+ VD KE     SP + V+ E   P    E  S+ Q     AP 
Sbjct: 817  NEASQFKPKGISEHTVLSVDGKEVIGPSSPDLVVASEHSFPPHTTEMTSECQ-----APP 871

Query: 794  IEPCAENRLDTKEEKSVEYEGDLKSGT----------AETEPVEQDSSQPSLPLVRADDP 843
            +       +   +E++VE E    S T          A  E  E++    SL L  A  P
Sbjct: 872  LSATPSEYVVLSDEEAVELERYTPSSTSASEFSVPPYATPEAQEEEIVHRSLNLKGASSP 931

Query: 844  LRLDQELQQPQTQEKTSNSLTED-------SKMANAKQLSSDAEAQKLGKPSAHASQSFC 896
            + L +E Q+        ++   +       ++ A  ++   D+    L  PS H   S  
Sbjct: 932  MNLSEEDQEDIGPFSPDSAFVSEFSFPPYATQEAEKREFECDSPI-CLTSPSEHTILS-- 988

Query: 897  ESSSETPFHFTLPKEGDI-IPPLTGATPPLIGHLKLEPKRHSTPIGISNYP-ESTIATSD 954
            +  +E    F+      + IPP   +        +LEP    T +  S Y   S     D
Sbjct: 989  DEDTEEAELFSPDSASQVSIPPFRISETE---KNELEPDSLLTAVSASGYSCFSEADEED 1045

Query: 955  VMSESMVETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGE 1014
            + S +     +    S K  +   P +     L    + P T+ SE++ +   E P T  
Sbjct: 1046 IGSTAATPVSEQFSSSQKQKAETFPLMSP---LEDLSLPPSTDKSEKA-EIKPEIPTT-- 1099

Query: 1015 RKNGSTAVAE--SVASPQKTMSVLSCICE-----------ARQENEARSE---DPPTTPI 1058
                ST+V+E   +A  QKT + L    E            + E EA S     P   P 
Sbjct: 1100 ----STSVSEYLILAQKQKTQAYLEPESEDLIPSHLTSEVEKGEREASSSVAAIPAALPA 1155

Query: 1059 RGNLLHFPSSQGEEEKEKLEGDHTIRQSQQP-----------MKPISPV-KDPVSPAS-- 1104
            + +++   +          +    I++ Q+P              +S V K+ + P S  
Sbjct: 1156 QSSIVKEETKPASPHSVLPDSVPAIKKEQEPTAALTLKAADEQMALSKVRKEEIVPDSQE 1215

Query: 1105 --------QKMVIQGPSSPQGE---AMVTDVLEDQKEG-------RSTNKENPSKALIER 1146
                    QKM  Q P+ P+ E   +++ D++++ K+G         T++    K     
Sbjct: 1216 ATAHVSQDQKMEPQPPNVPESEMKYSVLPDMVDEPKKGVKPKLVLNVTSELEQRKLSKNE 1275

Query: 1147 PSQNNIGIQTMECSLRVPETVSAATQTIKNVCEQGTSTVDQNFGKQDATVQTERGSGEKP 1206
            P          E SL  PE +SA    +K+  +  T+ +  +        Q E G     
Sbjct: 1276 PEVIKPYSPLKETSLSGPEALSAVKMEMKHDSKITTTPIVLHSASSGVEKQVEHGPPALA 1335

Query: 1207 VSAPGDD 1213
             SA  ++
Sbjct: 1336 FSALSEE 1342



 Score = 40.0 bits (92), Expect = 0.023
 Identities = 158/796 (19%), Positives = 278/796 (34%), Gaps = 128/796 (16%)

Query: 133  EEKGEELEQKEKEKE------EDTSGNTTHSLGAEDTASS-QLGFGVLELSQSQDVEENT 185
            E   + L   E EKE         S    HS+ +E  A   + G  V++ S SQ  +++ 
Sbjct: 1428 ETSSKHLAWSEAEKEIKFDSLPSVSSIAEHSVLSEVEAKEVKAGLPVIKTSSSQHSDKSE 1487

Query: 186  VPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTAQ---P 242
                 DK+ L   T           D+   +  +++S        +   ++P++      
Sbjct: 1488 EARVEDKQDLLFSTV---------CDSERLVSSQKKSLMSTSEVLEPEHELPLSLWGEIK 1538

Query: 243  SKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQI---QKSPEPEV 299
             K+  +   QN  PA    +P       A+   + +  A  L  + L +   +  P  EV
Sbjct: 1539 KKETELPSSQNVSPASKHIIPKGKDEETASSSPELENLASGLAPTLLLLSDDKNKPAVEV 1598

Query: 300  LSTQEDLFDQSNKTVS------------------------SDGCSTPSREEG--GCSLAS 333
             ST +  F    + V+                        S+  S   R+ G  G   A 
Sbjct: 1599 SSTAQGDFPSEKQDVALAELSLEPEKKDKPHQPLELPNAGSEFSSDLGRQSGSIGTKQAK 1658

Query: 334  TPAT-TLHLLQLSGQRSLVQDSLSTNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQD--- 389
            +P T T   +   G   L        + +L A S     + P I   S   +E  Q+   
Sbjct: 1659 SPITETEDSVLEKGPAELRSREGKEENRELCASS-----TMPAISELSSLLREESQNEEI 1713

Query: 390  KPMDTSVLSEEGGEPFQKKLQSGEPVELENPPLLPESTVSPQASTPI-------SQSTPV 442
            KP    ++S E  EP     + G P E + P       +S + S P         +  P+
Sbjct: 1714 KPFSPKIISLESKEPPASVAEGGNPEEFQ-PFTFSLKGLSEEVSHPADFKKGGNQEIGPL 1772

Query: 443  FPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGKKDGDMHSSSLTVECSKTSEIEPKN--- 499
             P G+L    + Q   DI      L E++      G  +SS +    ++ S+I P +   
Sbjct: 1773 PPTGNL----KAQVMGDIL---DKLSEET------GHPNSSQVLQSITEPSKIAPSDLLV 1819

Query: 500  SPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHRIDEDGENTQIEDTEPMSPVLNSKF 559
              +    +L  D    +   S  + S   + L   +     EN  +E ++       +  
Sbjct: 1820 EQKKTEKALHSDQTVKLPDVS--TSSEDKQDLGIKQFSLMRENLPLEQSKSFMTTKPADV 1877

Query: 560  VPAENDSILMNPAQDG------EVQLSQNDDKTKGDDTDTRDDISILATGCKGREETVAE 613
               + +   ++P  +       E   SQ++ +  G         + L  G     +  A 
Sbjct: 1878 KETKMEEFFISPKDENWMLGKPENVASQHEQRIAGSVQLDSSSSNELRPG-----QLKAA 1932

Query: 614  DVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEVEEIPETPCE 673
                D TC+   Q +P  A  S      L  +EA+   +      +S    E +      
Sbjct: 1933 VSSKDHTCEVRKQVLPHSAEESH-----LSSQEAVSALD------TSSGNTETLSSKSYS 1981

Query: 674  SQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSEAMEVETSVISIDSPQKLAI 733
            S+  +L EE     P  L L     + +   KE+     SE++ +E +   +  P K   
Sbjct: 1982 SEEVKLAEE-----PKSLVLAGNVERNIAEGKEIHSLMESESLLLEKANTELSWPSKED- 2035

Query: 734  LDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPLEGVEKCSDSQSWEDIA-- 791
              QE      E + +      SV  V  +  S  V  +  P EGVE    ++     +  
Sbjct: 2036 -SQEKIKLPPERFFQKPVSGLSVEQVKSETISSSVKTAHFPAEGVEPALGNEKEAHRSTP 2094

Query: 792  --PEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSLPLVRADDPLRLDQE 849
              PE +P  E+++   + K ++   D   G   +  V+  + +  +  + A +P      
Sbjct: 2095 PFPEEKPLEESKM--VQSKVID---DADEGKKPSPEVKIPTQRKPISSIHAREP------ 2143

Query: 850  LQQPQTQEKTSNSLTE 865
             Q P++ E T N  T+
Sbjct: 2144 -QSPESPEVTQNPPTQ 2158



 Score = 37.4 bits (85), Expect = 0.15
 Identities = 223/1167 (19%), Positives = 414/1167 (35%), Gaps = 227/1167 (19%)

Query: 131  VEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQL------------GFGVLELSQS 178
            VEE KG  ++  E   +++    T+  +  E+T    +             + + E    
Sbjct: 2414 VEESKGSLIDFSEDRLKKEMQNPTSLKISEEETKLRSVSPTEKKDNLENRSYTLAEKKVL 2473

Query: 179  QDVEENTVPYEV-DKEQL--QSVTTNSGYTRLSDVDANTAIKH---EEQSNEDIPI---- 228
             + + +  P E+ D  ++    +T  S  T L +  A+   +H    E  NE   I    
Sbjct: 2474 AEKQNSVAPLELRDSNEIGKTQITLGSRSTELKESKADAMPQHFYQNEDYNERPKIIVGS 2533

Query: 229  ----AEQSSKDIPVTAQPSK-DVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQE 283
                 E+    + V ++  K   H     N   + S +   S   S+   ++   + A  
Sbjct: 2534 EKEKGEEKENQVYVLSEGKKQQEHQPYSVNVAESMSRESDISLGHSLGETQSFSLVKATS 2593

Query: 284  LMESGLQIQKSPEPEV-----LSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATT 338
            + E    +     PE+     + TQ    ++S   V       P        +A +    
Sbjct: 2594 VTEKSEAMLAEAHPEIREAKAVGTQPHPLEESKVLVEKTKTFLP--------VALSCRDE 2645

Query: 339  LHLLQLSGQRSLVQDSLSTNSSDLVAPSPDAFRSTPF-----IVPSSPTEQEGRQDKPMD 393
            +    LS + +LV +  S +  D  +   + FR +       +  +  T ++G Q+K + 
Sbjct: 2646 IENHSLSQEGNLVLEKSSRDMPD-HSEEKEQFRESELSKGGSVDITKETVKQGFQEKAVG 2704

Query: 394  TSVLSEEGGEPFQKKLQSGEPVELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQ 453
            T     E  +   +K ++  PV L     +   ++S + +  + +S+   P  S     +
Sbjct: 2705 TQPRPLEESKVLVEKTKTFLPVVLSCHDEIENHSLSQEGNLVLEKSSRDMPDHS---EEK 2761

Query: 454  PQFSHDIFIPSPSLEEQSNDGKKDGDMHSSSLTV----ECSKTSEIEP----KNSPEDL- 504
             QF         S++      K+      S  T+    + +K+SE  P       P+ L 
Sbjct: 2762 EQFKESELWKGGSVDITKESMKEGFPSKESERTLARPFDETKSSETPPYLLSPVKPQTLA 2821

Query: 505  -GLSLTGDSCK------------------LMLSTSEYSQSPKMESLSSHRIDEDGENTQI 545
             G S   ++ K                  +  S  + S  PK   L S    E  E+T++
Sbjct: 2822 SGASPEINAVKKKEMPRSELTPERHTVHTIQTSKDDTSDVPKQSVLVSKHHLEAAEDTRV 2881

Query: 546  EDTEPMSPVLN--SKFVPAENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDISILATG 603
            +  EP+S   +  ++F+   + S       + E+     D   KG+D       + L+  
Sbjct: 2882 K--EPLSSAKSNYAQFISNTSASNADKMVSNKEMPKEPEDTYAKGEDFTVTSKPAGLSED 2939

Query: 604  CKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEA--MEIKEHHPEEGSSG 661
             K     ++E       C+  +   P       A  S +DQEE+  M+ K  + EE +S 
Sbjct: 2940 QKTAFSIISEG------CEILNIHAP-------AFISSIDQEESEQMQDKLEYLEEKAS- 2985

Query: 662  SEVEEIPETPCESQGEELKEENMESVPLHLSL-TETQSQGLCLQKEMPKKECSEAMEVET 720
               + IP             ++ E+V  H +L +  + + +   KE  +KE  +  E   
Sbjct: 2986 --FKTIP-----------LPDDSETVACHKTLKSRLEDEKVTPLKENKQKETHKTKE--- 3029

Query: 721  SVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPLEGVEK 780
              IS DS   L+ +   +   E++ +E+ T  D ++       P P    + + L   EK
Sbjct: 3030 -EISTDSETDLSFIQPTIP-SEEDYFEKYTLIDYNI------SPDPEKQKAPQKLNVEEK 3081

Query: 781  CSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSLPLVRA 840
             S   + E I+  +         +  E ++E+E DL         V+ D S         
Sbjct: 3082 LSKEVTEETISFPV---------SSVESALEHEYDL---------VKLDES--------F 3115

Query: 841  DDPLRLDQELQQPQTQEKTS--NSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSFCES 898
              P +    L  P+TQ + S   ++++D+K         D +++  G P   A +     
Sbjct: 3116 YGPEKGHNILSHPETQSQNSADRNVSKDTK--------RDVDSKSPGMPLFEAEEGVLSR 3167

Query: 899  SSETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIATSD-VMS 957
            +         P    +I P     PP +  L  +   +   +G     E T +  D V S
Sbjct: 3168 TQ------IFPTTIKVIDPEFLEEPPALAFLYKD--LYEEAVGEKKKEEETASEGDSVNS 3219

Query: 958  ESMVETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGERKN 1017
            E+   + +     G G         +K  L+  ++  +T  +++     LE     E++ 
Sbjct: 3220 EASFPSRNSDTDDGTG------IYFEKYILKDDILH-DTSLTQKDQGQGLE-----EKRV 3267

Query: 1018 GSTAVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGEEEKEKL 1077
            G     + +A+  +       IC  +   E +                    GE E    
Sbjct: 3268 GKDDSYQPIAAEGEIWGKFGTICREKSLEEQK-----------------GVYGEGESV-- 3308

Query: 1078 EGDHTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVTDVLEDQKEGRSTNKE 1137
              DH        M+  +P+ + V  A+QK+    P           VLE   E  S    
Sbjct: 3309 --DHVETVGNVAMQKKAPITEDVRVATQKISYAVPFED-----THHVLERADEAGSHG-- 3359

Query: 1138 NPSKALIERPSQNNIGIQTMECSLRVPETVSAATQTIKNVCEQGTSTVDQNFGKQDATVQ 1197
                        N +G  + E +L VP  VS   +   +    G + V +   ++   + 
Sbjct: 3360 ------------NEVGNASPEVNLNVPVQVSFPEEEFAS----GATHVQETSLEEPKILV 3403

Query: 1198 TERGSGEKPVSAPGDD----TESLHSQ 1220
                S E+  ++P  D    TESLH++
Sbjct: 3404 PPEPSEERLRNSPVQDEYEFTESLHNE 3430



 Score = 33.5 bits (75), Expect = 2.1
 Identities = 45/225 (20%), Positives = 84/225 (37%), Gaps = 22/225 (9%)

Query: 133  EEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQSQDVEENTVPYEVDK 192
            +EK +  E+ +K+K E       H L + DTA   L   V E  +  +    T   E+++
Sbjct: 3604 DEKAQSFEEVKKKKMEFLHEQMVHFLQSMDTAKDTLETIVREAEELDEAVFLTSFEEINE 3663

Query: 193  EQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTAQPSKDVHVVKEQ 252
              L ++ + +   ++    A +  +H + S+     ++Q  K + V              
Sbjct: 3664 RLLSAMESTASLEKMP--AAFSLFEHYDDSSAR---SDQMLKQVAV-------------- 3704

Query: 253  NPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQIQKSPEPEVLSTQEDLFDQSNK 312
             P P R E  P  P ++ +   A      +E +    Q+    EP+      +L ++   
Sbjct: 3705 -PQPPRLE--PQEPNSATSTTIAVYWSMNKEDVIDSFQVYCMEEPQDDQEVNELVEEYRL 3761

Query: 313  TVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSLST 357
            TV    C     E   C      A       L  +R++ + + ST
Sbjct: 3762 TVKESYCIFEDLEPDRCYQVWVMAVNFTGCSLPSERAIFRTAPST 3806


>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
           [Homo sapiens]
          Length = 916

 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 70/330 (21%), Positives = 133/330 (40%), Gaps = 42/330 (12%)

Query: 185 TVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTAQPSK 244
           T+  ++ K ++++      +  + ++   T ++ E+   E+   A   ++++ V+ +  K
Sbjct: 431 TISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTA--ITEELAVSMKEEK 488

Query: 245 DVHVVKEQNPPPARSEDMPFSPK-ASVAAMEAKEQLSAQELMESGLQIQKSPEPEVLSTQ 303
                +++  P A  E++          A E KE+   +E  E   Q ++  E E   + 
Sbjct: 489 KEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEG--QEEEEEEDEGAKSD 546

Query: 304 EDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSLS--TNSSD 361
           +     S K  SS+      +EEG      T A        + +   V++         +
Sbjct: 547 QAEEGGSEKEGSSE------KEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEE 600

Query: 362 LVAPS----PDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVEL 417
           LVA +    P+  +S    VP SP E++G+   P+  S + E+G  P  K      PVE 
Sbjct: 601 LVADAKVEKPEKAKSP---VPKSPVEEKGKS--PVPKSPVEEKGKSPVPKS-----PVEE 650

Query: 418 ENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGKKD 477
           +    +P+S V  +  +P+S+S PV      P+P           P    + ++  GK +
Sbjct: 651 KGKSPVPKSPVEEKGKSPVSKS-PVEEKAKSPVPKS---------PVEEAKSKAEVGKGE 700

Query: 478 GDMHSSSLTVECSKTSEIE-----PKNSPE 502
                     E  K  ++E     PK+ PE
Sbjct: 701 QKEEEEKEVKEAPKEEKVEKKEEKPKDVPE 730



 Score = 42.4 bits (98), Expect = 0.005
 Identities = 96/469 (20%), Positives = 165/469 (35%), Gaps = 72/469 (15%)

Query: 706  EMPKKECSEAMEVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPS 765
            E  K E  EA+   T  +++   ++     +  E KE+E   EA  E+ +     VK  +
Sbjct: 463  EDEKSEMEEALTAITEELAVSMKEEKK---EAAEEKEEEP--EAEEEEVAAKKSPVKATA 517

Query: 766  PRVDVSCEPLEGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEP 825
            P V       EG ++  + Q  E          E   +  +    E  G  K G++E E 
Sbjct: 518  PEVKEE----EGEKEEEEGQEEE----------EEEDEGAKSDQAEEGGSEKEGSSEKEE 563

Query: 826  VEQDSSQPSLPLVRADDPLRLDQELQQPQTQEKTSNSLTEDS-KMANAKQLSSDAEAQKL 884
             EQ+  +              + E +  + + K    + E S ++A  ++L +DA+ +K 
Sbjct: 564  GEQEEGE-------------TEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKP 610

Query: 885  GKPSAHASQSFCESSSETPF-HFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGIS 943
             K  +   +S  E   ++P     + ++G    P +         +   P        +S
Sbjct: 611  EKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVS 670

Query: 944  NYPESTIATSDVMSESMVETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESL 1003
              P    A S V  +S VE        GKG+     + + K               EE +
Sbjct: 671  KSPVEEKAKSPV-PKSPVEEAKSKAEVGKGEQKEEEEKEVK-----------EAPKEEKV 718

Query: 1004 QFNLEKPA-TGERKNGSTAVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNL 1062
            +   EKP    E+K   + V E   +   T   ++   +   E E + E  P        
Sbjct: 719  EKKEEKPKDVPEKKKAESPVKEEAVAEVVT---ITKSVKVHLEKETKEEGKPL------- 768

Query: 1063 LHFPSSQGEEEKEKLEGDHTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVT 1122
                  Q E+EKEK  G+    +            D  +  S+K  I      +G+  V 
Sbjct: 769  ------QQEKEKEKAGGEGGSEEEG---------SDKGAKGSRKEDIAVNGEVEGKEEVE 813

Query: 1123 DVLEDQKEGRSTNKENPSKALIERPSQNNIGIQTMECSLRVPETVSAAT 1171
               +++  GR   K   +  L   P+    G    E  + V +TV   T
Sbjct: 814  QETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEKIT 862



 Score = 39.7 bits (91), Expect = 0.029
 Identities = 93/426 (21%), Positives = 150/426 (35%), Gaps = 70/426 (16%)

Query: 608  EETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEVEEI 667
            EET  ED        S  +   +  T   A+S   +++EA E KE  PE     +E EE+
Sbjct: 458  EETKVEDE------KSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPE-----AEEEEV 506

Query: 668  P--ETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSE--AMEVETSVI 723
               ++P ++   E+KEE  E         E +      + E  K + +E    E E S  
Sbjct: 507  AAKKSPVKATAPEVKEEEGEKEEEEGQEEEEE------EDEGAKSDQAEEGGSEKEGSSE 560

Query: 724  SIDSPQKLAILDQELEHKEQEAWEEATSEDSS-------VVIVDVKEPSPRVDVSCEPLE 776
              +  Q+    + E E +E EA EE   E+ S        ++ D K   P    S  P  
Sbjct: 561  KEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKS 620

Query: 777  GVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSLP 836
             VE+   S       P+  P  E       +  VE +G          PVE+    P   
Sbjct: 621  PVEEKGKSP-----VPK-SPVEEKGKSPVPKSPVEEKG---KSPVPKSPVEEKGKSPV-- 669

Query: 837  LVRADDPLRLDQELQQPQTQEKTSNSLTE----DSKMANAKQLSSDAEAQKLGKPSAHAS 892
               +  P+    +   P++  + + S  E    + K    K++    + +K+ K      
Sbjct: 670  ---SKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPK 726

Query: 893  QSFCESSSETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIAT 952
                +  +E+P       + + +  +   T  +  HL+ E K    P+      E     
Sbjct: 727  DVPEKKKAESPV------KEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGE 780

Query: 953  SDVMSESMVETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPAT 1012
                 E          GS KG  G+  +           V+ E E  EE  Q   EK + 
Sbjct: 781  GGSEEE----------GSDKGAKGSRKE--------DIAVNGEVEGKEEVEQETKEKGSG 822

Query: 1013 GERKNG 1018
             E + G
Sbjct: 823  REEEKG 828



 Score = 35.0 bits (79), Expect = 0.73
 Identities = 39/186 (20%), Positives = 75/186 (40%), Gaps = 14/186 (7%)

Query: 127 SAPAVEEEKG----EELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQSQDVE 182
           +AP V+EE+G    EE +++E+E++E    +     G+E   SS+   G  E  +++   
Sbjct: 516 TAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEA 575

Query: 183 ENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDI---PIAEQSSKDIPVT 239
           E        KE+ +    +       ++ A+  ++  E++   +   P+ E+    +P +
Sbjct: 576 EGEEAEA--KEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKS 633

Query: 240 AQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQ-IQKSPEPE 298
               K    V +          +P SP       + K  +S   + E     + KSP  E
Sbjct: 634 PVEEKGKSPVPKSPVEEKGKSPVPKSP----VEEKGKSPVSKSPVEEKAKSPVPKSPVEE 689

Query: 299 VLSTQE 304
             S  E
Sbjct: 690 AKSKAE 695



 Score = 32.7 bits (73), Expect = 3.6
 Identities = 47/240 (19%), Positives = 98/240 (40%), Gaps = 27/240 (11%)

Query: 104 ISQVIEQLPQPNRTS----SVLGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLG 159
           + ++IE+    +  S    ++  ++ E A +++EEK E  E+KE+E E +          
Sbjct: 453 VEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSP 512

Query: 160 AEDTASSQLGFGVLELSQSQDVEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHE 219
            + TA         E+ + +  +E     E ++E+ +   ++      S+ + ++  K E
Sbjct: 513 VKATAP--------EVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSE-KEE 563

Query: 220 EQSNEDIPIAEQSSKDIPVTAQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQL 279
            +  E    AE   ++       +K+   V+E++   A  E++    K      +AK  +
Sbjct: 564 GEQEEGETEAEAEGEE-----AEAKEEKKVEEKSEEVATKEELVADAKVE-KPEKAKSPV 617

Query: 280 SAQELMESGLQIQKSPEPEVLSTQEDLFDQSNKTVSSDGCS----TPSREEGGCSLASTP 335
               + E G    KSP P+    ++         V   G S    +P  E+G   ++ +P
Sbjct: 618 PKSPVEEKG----KSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSP 673


>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
           [Homo sapiens]
          Length = 540

 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 70/330 (21%), Positives = 133/330 (40%), Gaps = 42/330 (12%)

Query: 185 TVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPVTAQPSK 244
           T+  ++ K ++++      +  + ++   T ++ E+   E+   A   ++++ V+ +  K
Sbjct: 55  TISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTA--ITEELAVSMKEEK 112

Query: 245 DVHVVKEQNPPPARSEDMPFSPK-ASVAAMEAKEQLSAQELMESGLQIQKSPEPEVLSTQ 303
                +++  P A  E++          A E KE+   +E  E   Q ++  E E   + 
Sbjct: 113 KEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEG--QEEEEEEDEGAKSD 170

Query: 304 EDLFDQSNKTVSSDGCSTPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSLS--TNSSD 361
           +     S K  SS+      +EEG      T A        + +   V++         +
Sbjct: 171 QAEEGGSEKEGSSE------KEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEE 224

Query: 362 LVAPS----PDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVEL 417
           LVA +    P+  +S    VP SP E++G+   P+  S + E+G  P  K      PVE 
Sbjct: 225 LVADAKVEKPEKAKSP---VPKSPVEEKGKS--PVPKSPVEEKGKSPVPKS-----PVEE 274

Query: 418 ENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGKKD 477
           +    +P+S V  +  +P+S+S PV      P+P           P    + ++  GK +
Sbjct: 275 KGKSPVPKSPVEEKGKSPVSKS-PVEEKAKSPVPKS---------PVEEAKSKAEVGKGE 324

Query: 478 GDMHSSSLTVECSKTSEIE-----PKNSPE 502
                     E  K  ++E     PK+ PE
Sbjct: 325 QKEEEEKEVKEAPKEEKVEKKEEKPKDVPE 354



 Score = 42.4 bits (98), Expect = 0.005
 Identities = 96/469 (20%), Positives = 165/469 (35%), Gaps = 72/469 (15%)

Query: 706  EMPKKECSEAMEVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPS 765
            E  K E  EA+   T  +++   ++     +  E KE+E   EA  E+ +     VK  +
Sbjct: 87   EDEKSEMEEALTAITEELAVSMKEEKK---EAAEEKEEEP--EAEEEEVAAKKSPVKATA 141

Query: 766  PRVDVSCEPLEGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEP 825
            P V       EG ++  + Q  E          E   +  +    E  G  K G++E E 
Sbjct: 142  PEVKEE----EGEKEEEEGQEEE----------EEEDEGAKSDQAEEGGSEKEGSSEKEE 187

Query: 826  VEQDSSQPSLPLVRADDPLRLDQELQQPQTQEKTSNSLTEDS-KMANAKQLSSDAEAQKL 884
             EQ+  +              + E +  + + K    + E S ++A  ++L +DA+ +K 
Sbjct: 188  GEQEEGE-------------TEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKP 234

Query: 885  GKPSAHASQSFCESSSETPF-HFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGIS 943
             K  +   +S  E   ++P     + ++G    P +         +   P        +S
Sbjct: 235  EKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVS 294

Query: 944  NYPESTIATSDVMSESMVETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESL 1003
              P    A S V  +S VE        GKG+     + + K               EE +
Sbjct: 295  KSPVEEKAKSPV-PKSPVEEAKSKAEVGKGEQKEEEEKEVK-----------EAPKEEKV 342

Query: 1004 QFNLEKPA-TGERKNGSTAVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNL 1062
            +   EKP    E+K   + V E   +   T   ++   +   E E + E  P        
Sbjct: 343  EKKEEKPKDVPEKKKAESPVKEEAVAEVVT---ITKSVKVHLEKETKEEGKPL------- 392

Query: 1063 LHFPSSQGEEEKEKLEGDHTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVT 1122
                  Q E+EKEK  G+    +            D  +  S+K  I      +G+  V 
Sbjct: 393  ------QQEKEKEKAGGEGGSEEEG---------SDKGAKGSRKEDIAVNGEVEGKEEVE 437

Query: 1123 DVLEDQKEGRSTNKENPSKALIERPSQNNIGIQTMECSLRVPETVSAAT 1171
               +++  GR   K   +  L   P+    G    E  + V +TV   T
Sbjct: 438  QETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEKIT 486



 Score = 39.7 bits (91), Expect = 0.029
 Identities = 93/426 (21%), Positives = 150/426 (35%), Gaps = 70/426 (16%)

Query: 608  EETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEVEEI 667
            EET  ED        S  +   +  T   A+S   +++EA E KE  PE     +E EE+
Sbjct: 82   EETKVEDE------KSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPE-----AEEEEV 130

Query: 668  P--ETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKEMPKKECSE--AMEVETSVI 723
               ++P ++   E+KEE  E         E +      + E  K + +E    E E S  
Sbjct: 131  AAKKSPVKATAPEVKEEEGEKEEEEGQEEEEE------EDEGAKSDQAEEGGSEKEGSSE 184

Query: 724  SIDSPQKLAILDQELEHKEQEAWEEATSEDSS-------VVIVDVKEPSPRVDVSCEPLE 776
              +  Q+    + E E +E EA EE   E+ S        ++ D K   P    S  P  
Sbjct: 185  KEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKS 244

Query: 777  GVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSLP 836
             VE+   S       P+  P  E       +  VE +G          PVE+    P   
Sbjct: 245  PVEEKGKSP-----VPK-SPVEEKGKSPVPKSPVEEKG---KSPVPKSPVEEKGKSPV-- 293

Query: 837  LVRADDPLRLDQELQQPQTQEKTSNSLTE----DSKMANAKQLSSDAEAQKLGKPSAHAS 892
               +  P+    +   P++  + + S  E    + K    K++    + +K+ K      
Sbjct: 294  ---SKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPK 350

Query: 893  QSFCESSSETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIAT 952
                +  +E+P       + + +  +   T  +  HL+ E K    P+      E     
Sbjct: 351  DVPEKKKAESPV------KEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGE 404

Query: 953  SDVMSESMVETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPAT 1012
                 E          GS KG  G+  +           V+ E E  EE  Q   EK + 
Sbjct: 405  GGSEEE----------GSDKGAKGSRKE--------DIAVNGEVEGKEEVEQETKEKGSG 446

Query: 1013 GERKNG 1018
             E + G
Sbjct: 447  REEEKG 452



 Score = 35.0 bits (79), Expect = 0.73
 Identities = 39/186 (20%), Positives = 75/186 (40%), Gaps = 14/186 (7%)

Query: 127 SAPAVEEEKG----EELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQSQDVE 182
           +AP V+EE+G    EE +++E+E++E    +     G+E   SS+   G  E  +++   
Sbjct: 140 TAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEA 199

Query: 183 ENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDI---PIAEQSSKDIPVT 239
           E        KE+ +    +       ++ A+  ++  E++   +   P+ E+    +P +
Sbjct: 200 EGEEAEA--KEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKS 257

Query: 240 AQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQ-IQKSPEPE 298
               K    V +          +P SP       + K  +S   + E     + KSP  E
Sbjct: 258 PVEEKGKSPVPKSPVEEKGKSPVPKSP----VEEKGKSPVSKSPVEEKAKSPVPKSPVEE 313

Query: 299 VLSTQE 304
             S  E
Sbjct: 314 AKSKAE 319



 Score = 32.7 bits (73), Expect = 3.6
 Identities = 47/240 (19%), Positives = 98/240 (40%), Gaps = 27/240 (11%)

Query: 104 ISQVIEQLPQPNRTS----SVLGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLG 159
           + ++IE+    +  S    ++  ++ E A +++EEK E  E+KE+E E +          
Sbjct: 77  VEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSP 136

Query: 160 AEDTASSQLGFGVLELSQSQDVEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHE 219
            + TA         E+ + +  +E     E ++E+ +   ++      S+ + ++  K E
Sbjct: 137 VKATAP--------EVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSE-KEE 187

Query: 220 EQSNEDIPIAEQSSKDIPVTAQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQL 279
            +  E    AE   ++       +K+   V+E++   A  E++    K      +AK  +
Sbjct: 188 GEQEEGETEAEAEGEE-----AEAKEEKKVEEKSEEVATKEELVADAKVE-KPEKAKSPV 241

Query: 280 SAQELMESGLQIQKSPEPEVLSTQEDLFDQSNKTVSSDGCS----TPSREEGGCSLASTP 335
               + E G    KSP P+    ++         V   G S    +P  E+G   ++ +P
Sbjct: 242 PKSPVEEKG----KSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSP 297


>gi|148806908 fibronectin type III domain containing 1 [Homo sapiens]
          Length = 1894

 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 154/667 (23%), Positives = 242/667 (36%), Gaps = 91/667 (13%)

Query: 833  PSLPLVRADDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQK--LGKPSAH 890
            P  P +RA     LD +  +   +E+  +   EDS M+      SD + QK  L  PS H
Sbjct: 520  PRKPQLRAKKAEELDLQSTEITGEEELGSR--EDSPMS-----PSDTQDQKRTLRPPSRH 572

Query: 891  ASQSFCESSSETPFHF-TLPK-EGDIIPPLTGATPPLIG---HLKLEPKRHSTPIGISNY 945
                     +        LP+ EG   P  + AT P  G        P  H++  G S+ 
Sbjct: 573  GHSVVAPGRTAVRARMPALPRREGVDKPGFSLATQPRPGAPPSASASPAHHASTQGTSHR 632

Query: 946  PESTIATSDVMSESMVETHDPILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQF 1005
            P    + +D     +V++ +     G      A     +  L     SP +   + S   
Sbjct: 633  PSLPASLND---NDLVDSDEDERAVGSLHPKGA-FAQPRPALSPSRQSPSSVLRDRSSVH 688

Query: 1006 NLEKPATGERKNGSTAVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLLHF 1065
               KPA+  R+   +  AE  +S     S LS        +   S   PT P     L  
Sbjct: 689  PGAKPASPARRTPHSGAAEEDSSASAPPSRLS------PPHGGSSRLLPTQPH----LSS 738

Query: 1066 PSSQGEEEKEKLEGDHTIRQSQQPMKPISPVKDPVSPASQKMVIQGPSSPQGEAMVTDVL 1125
            P S+G ++ E     ++   S+  M   S V   +S  +Q  V +G  +  GE+      
Sbjct: 739  PLSKGGKDGEDAPATNSNAPSRSTMS--SSVSSHLSSRTQ--VSEGAEASDGESHG---- 790

Query: 1126 EDQKEGRSTNKENPSKALIERPSQNNIGI---QTMECSLRVPETVSAATQTIKNVCEQGT 1182
            +  +E      E  ++ L  RP+  +  +   +    + R P   S              
Sbjct: 791  DGDREDGGRQAEATAQTLRARPASGHFHLLRHKPFAANGRSPSRFSIGRGPRLQPSSSPQ 850

Query: 1183 STVDQNFGKQDATVQTERGSGEKPVSAPGDDTESLHSQGEEEFDMPQPPHGHVLHRHMRT 1242
            STV        A  +    S   P  + G     +H  G+EE + P P    V++ H+ +
Sbjct: 851  STVPSR-----AHPRVPSHSDSHPKLSSG-----IH--GDEEDEKPLP--ATVVNDHVPS 896

Query: 1243 IREVRTLVTRVITDVYYVDGTEVERKVTEETEEPIVECQECETEVSPSQTGGSSGDLGDI 1302
                R  ++R   D+        +R  +   +EPI E        +P  TG  +   G  
Sbjct: 897  --SSRQPISRGWEDLR----RSPQRGASLHRKEPIPE--------NPKSTGADTHPQGKY 942

Query: 1303 SSFSSKASSLHRTSSGTS--LSAMHSSGSSGKGAGPLRGKTSGTEPADFALPSSRGGPGK 1360
            SS +SKA  + +++   +   S     GS+ + A P R   + ++      PS    P +
Sbjct: 943  SSLASKAQDVQQSTDADTEGHSPKAQPGSTDRHASPARPPAARSQQH----PSV---PRR 995

Query: 1361 LSP-RKGVSQTGTPVCEEDGDAGLGIRQGGKAPVTPR------GRGR---RGRPPSRT-- 1408
            ++P R    Q   PV       G   R  G++P  PR      GR R   +GR  S +  
Sbjct: 996  MTPGRAPQQQPPPPVATSQHHPGPQSRDAGRSPSQPRLSLTQAGRPRPTSQGRSHSSSDP 1055

Query: 1409 -TGTRETAVPGPLGIEDISPNLSPDDKSFSRVVP--RVPDSTRRTDVGAGALRRSDSPEI 1465
             T +    +P  L  +D     S DD S        R P    R    A +L +    E 
Sbjct: 1056 YTASSRGMLPTALQNQDEDAQGSYDDDSTEVEAQDVRAPAHAARAKEAAASLPKHQQVES 1115

Query: 1466 PFQAAAG 1472
            P  A AG
Sbjct: 1116 PTGAGAG 1122


>gi|226437579 NAC alpha domain containing [Homo sapiens]
          Length = 1562

 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 126/654 (19%), Positives = 223/654 (34%), Gaps = 83/654 (12%)

Query: 59   LDVVSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPNRTS 118
            ++V +     AGEE  D  +G  +      +  P      +  G  S   E+LP P   +
Sbjct: 496  VEVATRVTPQAGEEETDSTAG--QESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEET 553

Query: 119  SVLGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQS 178
            S L +  +S   ++EE G +L    K      +  T     A++  +      +      
Sbjct: 554  S-LTLCPDSPQNLKEEGGLDLPSGRKP----VAAATIVPRQAKEDLTLPQDSAMTPPLPL 608

Query: 179  QDVEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPV 238
            QD + ++ P  V    + S     G T   D      +  ++      P    ++  +  
Sbjct: 609  QDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQ 668

Query: 239  TAQPSKDVHVVKEQNPP-PARSEDMPFSPK----ASVAAMEAKEQLSAQE-------LME 286
             A+    +       PP P +  D+  +PK    A++ + +A+E L+  +       L  
Sbjct: 669  QAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPL 728

Query: 287  SGLQIQKSPEPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTP----ATTLHLL 342
                +  +P+P   +T      +   T+  D   TP        L+S P    A T+   
Sbjct: 729  QDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQ 788

Query: 343  QLSGQRSLVQDSLSTNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGG 402
            Q     +L QDS  T                   +P   T+           +++S++  
Sbjct: 789  QAEEGLTLPQDSAMTPP-----------------LPLQDTDLSSAPKPVAAATIVSQQAE 831

Query: 403  EPFQKKLQSGEPVELENPPLLPESTVSPQASTPISQSTPV---------FPPGSLPIPSQ 453
            E       S        PPL  + T    A  P++ +TPV          P  S   P  
Sbjct: 832  EGLTLPQDSAM-----TPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTPPL 886

Query: 454  PQFSHDIFI---PSPSLEEQSNDGKKDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTG 510
            P    D+     P  +    S   ++   +   S         +  P + PE L ++   
Sbjct: 887  PLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATP- 945

Query: 511  DSCKLMLSTSEYSQSPKMESLSSHRIDEDGENTQIEDT-EPMSPVLNSKFVPAENDSILM 569
                     +E   +P  E +++    E GE        E  +  L +   PA  D +  
Sbjct: 946  -----QTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQ 1000

Query: 570  N---PAQDGEVQLSQNDDKTKGDDTDTRDDISILATGCKGREETVAE-------DVCIDL 619
            +   PA +     +  +D    D T   + +S L     G  E +AE       + C++ 
Sbjct: 1001 DDPQPAAEAGTPWAAQED---ADSTLGMEALS-LPEPASGAGEEIAEALSRPGREACLEA 1056

Query: 620  TCDSGSQAVPSPATRSEALSSVLDQEEAME--IKEHHPEEGSSGSEVEEIPETP 671
               +G  A P  + + E L     QE  ++   +EH P     G+   E+P+ P
Sbjct: 1057 RAHTGDGAKPD-SPQKETLEVENQQEGGLKPLAQEHGPRSALGGA--REVPDAP 1107



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 136/625 (21%), Positives = 228/625 (36%), Gaps = 89/625 (14%)

Query: 350 LVQDSLSTNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGG----EPF 405
           L+ + LS+ +    AP P      P IV    T Q     +   T++  +EGG    +P 
Sbjct: 95  LLPEGLSSQALSTEAPLPATLE--PRIVMGEETCQALLSPRAARTALRDQEGGHASPDPP 152

Query: 406 QKKLQSGEPVELENPPLLPESTVSPQASTPISQSTPVFP---PGSLPIPSQPQFSHDIFI 462
            +    G+ + + +PP  P+S  +P  STP   +  + P   P      S+ +   D  +
Sbjct: 153 PELCSQGD-LSVPSPPPDPDSFFTPP-STPTKTTYALLPACGPHGDARDSEAEL-RDELL 209

Query: 463 PSPSLEEQSNDGKKDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSC-KLMLSTSE 521
            SP      +    DGD  +SS +   S  +  E  + P   GLS  G    +  L  + 
Sbjct: 210 DSPPASPSGSYITADGDSWASSPSCSLSLLAPAEGLDFPSGWGLSPQGSMVDERELHPAG 269

Query: 522 YSQSPKME-SLSSHRIDEDGENTQIEDTEPMS--PVLNSKFVP----------------- 561
             + P  E SLS+      G+     D + ++  P++ +  +P                 
Sbjct: 270 TPEPPSSESSLSADSSSSWGQEGHFFDLDFLANDPMIPAALLPFQGSLIFQVEAVEVTPL 329

Query: 562 ---AENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDISILATGCKGREETVA-EDVCI 617
               E +  + +P   G++     +D T      +  D+SI     +G +E  A  D   
Sbjct: 330 SPEEEEEEAVADPDPGGDLAGEGEEDSTSASFLQSLSDLSI----TEGMDEAFAFRDDTS 385

Query: 618 DLTCDSGSQAVP-------------SPATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEV 664
             + DS S +               + AT  +      ++E     K    ++G+    V
Sbjct: 386 AASSDSDSASYAEADDERLYSGEPHAQATLLQDSVQKTEEESGGGAKGLQAQDGTVSWAV 445

Query: 665 EEIPETPCE----SQGEEL-KEENMESVPLHLSLTETQSQGLC-----LQKEMPKKECSE 714
           E  P+T       SQ +EL  E   E + L    T T +         LQ E+  +   +
Sbjct: 446 EAAPQTSDRGAYLSQRQELISEVTEEGLALGQESTATVTPHTLQVAPGLQVEVATRVTPQ 505

Query: 715 AMEVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEP 774
           A E ET     DS          +    QE   E   ++S   +   K P+P+ + S   
Sbjct: 506 AGEEET-----DSTAGQESAAMAMPQPSQEGISEILGQES---VTAEKLPTPQEETSLTL 557

Query: 775 LEGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVE-QDSSQP 833
                +    +   D+    +P A   +  ++ K    +  L   +A T P+  QD+   
Sbjct: 558 CPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKE---DLTLPQDSAMTPPLPLQDTDLS 614

Query: 834 SLPLVRADDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQ 893
           S P      P+     + Q   Q +   +L +DS M     L  D E     KP A A+ 
Sbjct: 615 SAP-----KPVAAATIVSQ---QAEEGLTLPQDSVMTPPLPL-QDTELSSAPKPVAAATL 665

Query: 894 SFCESSSETPFHFTLPKEGDIIPPL 918
                S +     TLP++  + PPL
Sbjct: 666 ----VSQQAEEGLTLPQDSAMTPPL 686



 Score = 40.8 bits (94), Expect = 0.013
 Identities = 216/1053 (20%), Positives = 358/1053 (33%), Gaps = 207/1053 (19%)

Query: 220  EQSNEDIPIAEQSSKDI-PVTAQ--PSKDVHVVKEQNPPPARSE-DMPFSPKASVAAMEA 275
            E + E + + ++S+  + P T Q  P   V V     P     E D     +++  AM  
Sbjct: 467  EVTEEGLALGQESTATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQ 526

Query: 276  KEQLSAQELM-ESGLQIQKSPEPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLAS- 333
              Q    E++ +  +  +K P P+         ++++ T+  D      +EEGG  L S 
Sbjct: 527  PSQEGISEILGQESVTAEKLPTPQ---------EETSLTLCPDSPQN-LKEEGGLDLPSG 576

Query: 334  ---TPATTLHLLQLSGQRSLVQDSLST-----NSSDLV-APSPDAFRSTPFIVPSSPTEQ 384
                 A T+   Q     +L QDS  T       +DL  AP P A  +       S   +
Sbjct: 577  RKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIV-----SQQAE 631

Query: 385  EGR---QDKPMDTSVLSEEGGEPFQKKLQSGEPVELENPPLLPESTVSPQASTPI----- 436
            EG    QD  M   +       P Q    S  P      P+   + VS QA   +     
Sbjct: 632  EGLTLPQDSVMTPPL-------PLQDTELSSAP-----KPVAAATLVSQQAEEGLTLPQD 679

Query: 437  SQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEE-----QSNDGKKDGDMHSSSLTVECSK 491
            S  TP  P     + S P+      + S   EE     Q +       +  + L+     
Sbjct: 680  SAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKP 739

Query: 492  TSEIEPKNSPEDLGLSLTGDSCK---LMLSTSEYSQSPKMESLSSHRIDEDGENTQIEDT 548
             +     +   + GL+L  DS     L L  ++ S +PK  + ++    +  E   +   
Sbjct: 740  VAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQD 799

Query: 549  EPMSPVL-------NSKFVPAENDSILMNPAQDGEVQLSQNDDKTKG---DDTDTRDDIS 598
              M+P L       +S   P    +I+   A++G + L Q+   T      DTD      
Sbjct: 800  SAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEG-LTLPQDSAMTPPLPLQDTDLSSAPK 858

Query: 599  ILATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEG 658
             +A      ++  AE+    LT    S   P    +   LSS      A        EEG
Sbjct: 859  PVAAATPVSQQ--AEE---GLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEG 913

Query: 659  SSGSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKE------------ 706
             +      +P+    +    L++    S P  L++   Q+    LQ E            
Sbjct: 914  LT------LPQDSAMTAPLPLQDTGPTSGPEPLAVATPQT----LQAEAGCAPGTEPVAT 963

Query: 707  MPKKECSEAM-------EVETSVISIDSPQKLAILDQELEHKEQEA---WEEATSEDSSV 756
            M ++E  EA+       E   ++ ++  P  L  + Q+      EA   W      DS++
Sbjct: 964  MAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTL 1023

Query: 757  VIVDVKEPSPRVDVSCEPLEGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDL 816
             +  +  P P      E  E + +           P  E C E R  T +    +     
Sbjct: 1024 GMEALSLPEPASGAGEEIAEALSR-----------PGREACLEARAHTGDGAKPD----- 1067

Query: 817  KSGTAETEPVEQDSSQPSLPLVRADDPLR-LDQELQQPQTQEKTSNSLTEDSKMANAKQL 875
             S   ET  VE        PL +   P   L    + P         +++   ++ A++ 
Sbjct: 1068 -SPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREE 1126

Query: 876  S--SDAEAQKLGKPSAHASQSFCESSSETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEP 933
               S     +   PSA A+++  +S  E+                 GA   L       P
Sbjct: 1127 RGLSGKSTPEPTLPSAVATEASLDSCPESS---------------VGAVSSLDRGCPDAP 1171

Query: 934  KRHSTPIGISNYPESTIATSDVMSESMVETHDPILGSGKGDSG-AAPDVDDKLCLRMKLV 992
               S P   S  PE                  P+LG G  +     P V     L   L+
Sbjct: 1172 APTSAPT--SQQPE------------------PVLGLGSVEQPHEVPSV-----LGTPLL 1206

Query: 993  SPETEASEESLQFNLEKPATGERKNGSTAVAESVASPQKTMSVLSCICEARQENEARSED 1052
             P    ++      +++P  G   +    +A +   P +  +   C+C+  QE+    E+
Sbjct: 1207 QPPENLAKGQPSTPVDRPL-GPDPSAPGTLAGAALPPLEPPA--PCLCQDPQEDSVEDEE 1263

Query: 1053 PPTTPIRGNLLHFPSSQGEEEKEKLEGDHTIRQSQQP---MKPISPVKDP---------- 1099
            PP     G+L   P   G +         T      P   + P SP+  P          
Sbjct: 1264 PP-----GSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDL 1318

Query: 1100 ---VSPASQKMVIQGPSSPQGEAMVT--------DVLEDQKE---GRSTNKENPSKALIE 1145
               + P  Q     GP SP G   ++        D LE+      G   + ++  ++  E
Sbjct: 1319 ALQILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAE 1378

Query: 1146 RPSQNNIGIQTMECSLRVP-----ETVSAATQT 1173
               Q+ +  QT++C  + P     ET++ A Q+
Sbjct: 1379 LDEQDILAPQTVQCPAQAPAGGSEETIAKAKQS 1411



 Score = 32.3 bits (72), Expect = 4.7
 Identities = 124/651 (19%), Positives = 237/651 (36%), Gaps = 91/651 (13%)

Query: 631  PATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEVEEIPETPCESQGEE--LKEENMESVP 688
            PA       S++ Q EA+E+    PEE    +  +  P      +GEE       ++S+ 
Sbjct: 307  PAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDPGGDLAGEGEEDSTSASFLQSLS 366

Query: 689  LHLSLTETQSQGLCLQKE-----MPKKECSEAMEVETSVISIDSPQKLAILDQELEHKEQ 743
              LS+TE   +    + +           S A   +  + S +   +  +L   ++  E+
Sbjct: 367  -DLSITEGMDEAFAFRDDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSVQKTEE 425

Query: 744  EAWEEA---TSEDSSV--VIVDVKEPSPRVDVSCEPLEGVEKCSD------SQSWEDIAP 792
            E+   A    ++D +V   +    + S R     +  E + + ++       +S   + P
Sbjct: 426  ESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQESTATVTP 485

Query: 793  ---EIEPCAENRLDTK-EEKSVEYEGDLKSGTAETEPVEQDSSQPSLPLVRADDPLRLDQ 848
               ++ P  +  + T+   ++ E E D  +G           SQ  +  +   + +  + 
Sbjct: 486  HTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQESVTAE- 544

Query: 849  ELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSFCESSSETPFHFTL 908
              + P  QE+TS +L  DS     ++   D  + +  KP A A+    ++  +     TL
Sbjct: 545  --KLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGR--KPVAAATIVPRQAKED----LTL 596

Query: 909  PKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPES--TIATSDVMSESMVETHDP 966
            P++  + PPL    P     L   PK  +    +S   E   T+    VM+  +      
Sbjct: 597  PQDSAMTPPL----PLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPL------ 646

Query: 967  ILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGERKNGSTAVAESV 1026
                        P  D +L    K V+  T  S+++ +  L  P               +
Sbjct: 647  ------------PLQDTELSSAPKPVAAATLVSQQA-EEGLTLPQDSAMTPPLPLQDTDL 693

Query: 1027 ASPQKTMSVLSCICEARQENEARSED---PPTTPIRGNLLHF---PSSQGEEEKEKLEGD 1080
            +S  K ++  + + +  +E     +D    P  P++   L     P +      ++ E  
Sbjct: 694  SSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEG 753

Query: 1081 HTIRQSQQPMKPISPVKD--------PVSPAS--QKMVIQGPSSPQGEAMVTDVLEDQKE 1130
             T+ Q    M P  P++D        PV+ A+   +   +G + PQ  AM   +     +
Sbjct: 754  LTLPQ-DSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTD 812

Query: 1131 GRSTNKENPSKALIERPSQNN------------IGIQTMECSLRVPETVSAATQTIKNVC 1178
              S  K   +  ++ + ++              + +Q  + S   P+ V+AAT   +   
Sbjct: 813  LSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLS-SAPKPVAAATPVSQQAE 871

Query: 1179 EQGTSTVDQNFGKQDATVQTERGSGEKPVSAPGDDTESLHSQGEEEFDMPQ 1229
            E  T   D           T+  S  KPV+A       +  Q EE   +PQ
Sbjct: 872  EGLTLPQDSAMTPPLPLQDTDLSSAPKPVAA----ATPVSQQAEEGLTLPQ 918


>gi|239743134 PREDICTED: NAC alpha domain containing [Homo sapiens]
          Length = 1562

 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 126/654 (19%), Positives = 223/654 (34%), Gaps = 83/654 (12%)

Query: 59   LDVVSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPNRTS 118
            ++V +     AGEE  D  +G  +      +  P      +  G  S   E+LP P   +
Sbjct: 496  VEVATRVTPQAGEEETDSTAG--QESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEET 553

Query: 119  SVLGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQS 178
            S L +  +S   ++EE G +L    K      +  T     A++  +      +      
Sbjct: 554  S-LTLCPDSPQNLKEEGGLDLPSGRKP----VAAATIVPRQAKEDLTLPQDSAMTPPLPL 608

Query: 179  QDVEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPV 238
            QD + ++ P  V    + S     G T   D      +  ++      P    ++  +  
Sbjct: 609  QDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQ 668

Query: 239  TAQPSKDVHVVKEQNPP-PARSEDMPFSPK----ASVAAMEAKEQLSAQE-------LME 286
             A+    +       PP P +  D+  +PK    A++ + +A+E L+  +       L  
Sbjct: 669  QAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPL 728

Query: 287  SGLQIQKSPEPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTP----ATTLHLL 342
                +  +P+P   +T      +   T+  D   TP        L+S P    A T+   
Sbjct: 729  QDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQ 788

Query: 343  QLSGQRSLVQDSLSTNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGG 402
            Q     +L QDS  T                   +P   T+           +++S++  
Sbjct: 789  QAEEGLTLPQDSAMTPP-----------------LPLQDTDLSSAPKPVAAATIVSQQAE 831

Query: 403  EPFQKKLQSGEPVELENPPLLPESTVSPQASTPISQSTPV---------FPPGSLPIPSQ 453
            E       S        PPL  + T    A  P++ +TPV          P  S   P  
Sbjct: 832  EGLTLPQDSAM-----TPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTPPL 886

Query: 454  PQFSHDIFI---PSPSLEEQSNDGKKDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTG 510
            P    D+     P  +    S   ++   +   S         +  P + PE L ++   
Sbjct: 887  PLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATP- 945

Query: 511  DSCKLMLSTSEYSQSPKMESLSSHRIDEDGENTQIEDT-EPMSPVLNSKFVPAENDSILM 569
                     +E   +P  E +++    E GE        E  +  L +   PA  D +  
Sbjct: 946  -----QTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQ 1000

Query: 570  N---PAQDGEVQLSQNDDKTKGDDTDTRDDISILATGCKGREETVAE-------DVCIDL 619
            +   PA +     +  +D    D T   + +S L     G  E +AE       + C++ 
Sbjct: 1001 DDPQPAAEAGTPWAAQED---ADSTLGMEALS-LPEPASGAGEEIAEALSRPGREACLEA 1056

Query: 620  TCDSGSQAVPSPATRSEALSSVLDQEEAME--IKEHHPEEGSSGSEVEEIPETP 671
               +G  A P  + + E L     QE  ++   +EH P     G+   E+P+ P
Sbjct: 1057 RAHTGDGAKPD-SPQKETLEVENQQEGGLKPLAQEHGPRSALGGA--REVPDAP 1107



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 136/625 (21%), Positives = 228/625 (36%), Gaps = 89/625 (14%)

Query: 350 LVQDSLSTNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGG----EPF 405
           L+ + LS+ +    AP P      P IV    T Q     +   T++  +EGG    +P 
Sbjct: 95  LLPEGLSSQALSTEAPLPATLE--PRIVMGEETCQALLSPRAARTALRDQEGGHASPDPP 152

Query: 406 QKKLQSGEPVELENPPLLPESTVSPQASTPISQSTPVFP---PGSLPIPSQPQFSHDIFI 462
            +    G+ + + +PP  P+S  +P  STP   +  + P   P      S+ +   D  +
Sbjct: 153 PELCSQGD-LSVPSPPPDPDSFFTPP-STPTKTTYALLPACGPHGDARDSEAEL-RDELL 209

Query: 463 PSPSLEEQSNDGKKDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSC-KLMLSTSE 521
            SP      +    DGD  +SS +   S  +  E  + P   GLS  G    +  L  + 
Sbjct: 210 DSPPASPSGSYITADGDSWASSPSCSLSLLAPAEGLDFPSGWGLSPQGSMVDERELHPAG 269

Query: 522 YSQSPKME-SLSSHRIDEDGENTQIEDTEPMS--PVLNSKFVP----------------- 561
             + P  E SLS+      G+     D + ++  P++ +  +P                 
Sbjct: 270 TPEPPSSESSLSADSSSSWGQEGHFFDLDFLANDPMIPAALLPFQGSLIFQVEAVEVTPL 329

Query: 562 ---AENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDISILATGCKGREETVA-EDVCI 617
               E +  + +P   G++     +D T      +  D+SI     +G +E  A  D   
Sbjct: 330 SPEEEEEEAVADPDPGGDLAGEGEEDSTSASFLQSLSDLSI----TEGMDEAFAFRDDTS 385

Query: 618 DLTCDSGSQAVP-------------SPATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEV 664
             + DS S +               + AT  +      ++E     K    ++G+    V
Sbjct: 386 AASSDSDSASYAEADDERLYSGEPHAQATLLQDSVQKTEEESGGGAKGLQAQDGTVSWAV 445

Query: 665 EEIPETPCE----SQGEEL-KEENMESVPLHLSLTETQSQGLC-----LQKEMPKKECSE 714
           E  P+T       SQ +EL  E   E + L    T T +         LQ E+  +   +
Sbjct: 446 EAAPQTSDRGAYLSQRQELISEVTEEGLALGQESTATVTPHTLQVAPGLQVEVATRVTPQ 505

Query: 715 AMEVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEP 774
           A E ET     DS          +    QE   E   ++S   +   K P+P+ + S   
Sbjct: 506 AGEEET-----DSTAGQESAAMAMPQPSQEGISEILGQES---VTAEKLPTPQEETSLTL 557

Query: 775 LEGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVE-QDSSQP 833
                +    +   D+    +P A   +  ++ K    +  L   +A T P+  QD+   
Sbjct: 558 CPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKE---DLTLPQDSAMTPPLPLQDTDLS 614

Query: 834 SLPLVRADDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQ 893
           S P      P+     + Q   Q +   +L +DS M     L  D E     KP A A+ 
Sbjct: 615 SAP-----KPVAAATIVSQ---QAEEGLTLPQDSVMTPPLPL-QDTELSSAPKPVAAATL 665

Query: 894 SFCESSSETPFHFTLPKEGDIIPPL 918
                S +     TLP++  + PPL
Sbjct: 666 ----VSQQAEEGLTLPQDSAMTPPL 686



 Score = 40.8 bits (94), Expect = 0.013
 Identities = 216/1053 (20%), Positives = 358/1053 (33%), Gaps = 207/1053 (19%)

Query: 220  EQSNEDIPIAEQSSKDI-PVTAQ--PSKDVHVVKEQNPPPARSE-DMPFSPKASVAAMEA 275
            E + E + + ++S+  + P T Q  P   V V     P     E D     +++  AM  
Sbjct: 467  EVTEEGLALGQESTATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQ 526

Query: 276  KEQLSAQELM-ESGLQIQKSPEPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLAS- 333
              Q    E++ +  +  +K P P+         ++++ T+  D      +EEGG  L S 
Sbjct: 527  PSQEGISEILGQESVTAEKLPTPQ---------EETSLTLCPDSPQN-LKEEGGLDLPSG 576

Query: 334  ---TPATTLHLLQLSGQRSLVQDSLST-----NSSDLV-APSPDAFRSTPFIVPSSPTEQ 384
                 A T+   Q     +L QDS  T       +DL  AP P A  +       S   +
Sbjct: 577  RKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIV-----SQQAE 631

Query: 385  EGR---QDKPMDTSVLSEEGGEPFQKKLQSGEPVELENPPLLPESTVSPQASTPI----- 436
            EG    QD  M   +       P Q    S  P      P+   + VS QA   +     
Sbjct: 632  EGLTLPQDSVMTPPL-------PLQDTELSSAP-----KPVAAATLVSQQAEEGLTLPQD 679

Query: 437  SQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEE-----QSNDGKKDGDMHSSSLTVECSK 491
            S  TP  P     + S P+      + S   EE     Q +       +  + L+     
Sbjct: 680  SAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKP 739

Query: 492  TSEIEPKNSPEDLGLSLTGDSCK---LMLSTSEYSQSPKMESLSSHRIDEDGENTQIEDT 548
             +     +   + GL+L  DS     L L  ++ S +PK  + ++    +  E   +   
Sbjct: 740  VAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQD 799

Query: 549  EPMSPVL-------NSKFVPAENDSILMNPAQDGEVQLSQNDDKTKG---DDTDTRDDIS 598
              M+P L       +S   P    +I+   A++G + L Q+   T      DTD      
Sbjct: 800  SAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEG-LTLPQDSAMTPPLPLQDTDLSSAPK 858

Query: 599  ILATGCKGREETVAEDVCIDLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEG 658
             +A      ++  AE+    LT    S   P    +   LSS      A        EEG
Sbjct: 859  PVAAATPVSQQ--AEE---GLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEG 913

Query: 659  SSGSEVEEIPETPCESQGEELKEENMESVPLHLSLTETQSQGLCLQKE------------ 706
             +      +P+    +    L++    S P  L++   Q+    LQ E            
Sbjct: 914  LT------LPQDSAMTAPLPLQDTGPTSGPEPLAVATPQT----LQAEAGCAPGTEPVAT 963

Query: 707  MPKKECSEAM-------EVETSVISIDSPQKLAILDQELEHKEQEA---WEEATSEDSSV 756
            M ++E  EA+       E   ++ ++  P  L  + Q+      EA   W      DS++
Sbjct: 964  MAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTL 1023

Query: 757  VIVDVKEPSPRVDVSCEPLEGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDL 816
             +  +  P P      E  E + +           P  E C E R  T +    +     
Sbjct: 1024 GMEALSLPEPASGAGEEIAEALSR-----------PGREACLEARAHTGDGAKPD----- 1067

Query: 817  KSGTAETEPVEQDSSQPSLPLVRADDPLR-LDQELQQPQTQEKTSNSLTEDSKMANAKQL 875
             S   ET  VE        PL +   P   L    + P         +++   ++ A++ 
Sbjct: 1068 -SPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREE 1126

Query: 876  S--SDAEAQKLGKPSAHASQSFCESSSETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEP 933
               S     +   PSA A+++  +S  E+                 GA   L       P
Sbjct: 1127 RGLSGKSTPEPTLPSAVATEASLDSCPESS---------------VGAVSSLDRGCPDAP 1171

Query: 934  KRHSTPIGISNYPESTIATSDVMSESMVETHDPILGSGKGDSG-AAPDVDDKLCLRMKLV 992
               S P   S  PE                  P+LG G  +     P V     L   L+
Sbjct: 1172 APTSAPT--SQQPE------------------PVLGLGSVEQPHEVPSV-----LGTPLL 1206

Query: 993  SPETEASEESLQFNLEKPATGERKNGSTAVAESVASPQKTMSVLSCICEARQENEARSED 1052
             P    ++      +++P  G   +    +A +   P +  +   C+C+  QE+    E+
Sbjct: 1207 QPPENLAKGQPSTPVDRPL-GPDPSAPGTLAGAALPPLEPPA--PCLCQDPQEDSVEDEE 1263

Query: 1053 PPTTPIRGNLLHFPSSQGEEEKEKLEGDHTIRQSQQP---MKPISPVKDP---------- 1099
            PP     G+L   P   G +         T      P   + P SP+  P          
Sbjct: 1264 PP-----GSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDL 1318

Query: 1100 ---VSPASQKMVIQGPSSPQGEAMVT--------DVLEDQKE---GRSTNKENPSKALIE 1145
               + P  Q     GP SP G   ++        D LE+      G   + ++  ++  E
Sbjct: 1319 ALQILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAE 1378

Query: 1146 RPSQNNIGIQTMECSLRVP-----ETVSAATQT 1173
               Q+ +  QT++C  + P     ET++ A Q+
Sbjct: 1379 LDEQDILAPQTVQCPAQAPAGGSEETIAKAKQS 1411



 Score = 32.3 bits (72), Expect = 4.7
 Identities = 124/651 (19%), Positives = 237/651 (36%), Gaps = 91/651 (13%)

Query: 631  PATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEVEEIPETPCESQGEE--LKEENMESVP 688
            PA       S++ Q EA+E+    PEE    +  +  P      +GEE       ++S+ 
Sbjct: 307  PAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDPGGDLAGEGEEDSTSASFLQSLS 366

Query: 689  LHLSLTETQSQGLCLQKE-----MPKKECSEAMEVETSVISIDSPQKLAILDQELEHKEQ 743
              LS+TE   +    + +           S A   +  + S +   +  +L   ++  E+
Sbjct: 367  -DLSITEGMDEAFAFRDDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSVQKTEE 425

Query: 744  EAWEEA---TSEDSSV--VIVDVKEPSPRVDVSCEPLEGVEKCSD------SQSWEDIAP 792
            E+   A    ++D +V   +    + S R     +  E + + ++       +S   + P
Sbjct: 426  ESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQESTATVTP 485

Query: 793  ---EIEPCAENRLDTK-EEKSVEYEGDLKSGTAETEPVEQDSSQPSLPLVRADDPLRLDQ 848
               ++ P  +  + T+   ++ E E D  +G           SQ  +  +   + +  + 
Sbjct: 486  HTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQESVTAE- 544

Query: 849  ELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQSFCESSSETPFHFTL 908
              + P  QE+TS +L  DS     ++   D  + +  KP A A+    ++  +     TL
Sbjct: 545  --KLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGR--KPVAAATIVPRQAKED----LTL 596

Query: 909  PKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPES--TIATSDVMSESMVETHDP 966
            P++  + PPL    P     L   PK  +    +S   E   T+    VM+  +      
Sbjct: 597  PQDSAMTPPL----PLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPL------ 646

Query: 967  ILGSGKGDSGAAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPATGERKNGSTAVAESV 1026
                        P  D +L    K V+  T  S+++ +  L  P               +
Sbjct: 647  ------------PLQDTELSSAPKPVAAATLVSQQA-EEGLTLPQDSAMTPPLPLQDTDL 693

Query: 1027 ASPQKTMSVLSCICEARQENEARSED---PPTTPIRGNLLHF---PSSQGEEEKEKLEGD 1080
            +S  K ++  + + +  +E     +D    P  P++   L     P +      ++ E  
Sbjct: 694  SSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEG 753

Query: 1081 HTIRQSQQPMKPISPVKD--------PVSPAS--QKMVIQGPSSPQGEAMVTDVLEDQKE 1130
             T+ Q    M P  P++D        PV+ A+   +   +G + PQ  AM   +     +
Sbjct: 754  LTLPQ-DSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTD 812

Query: 1131 GRSTNKENPSKALIERPSQNN------------IGIQTMECSLRVPETVSAATQTIKNVC 1178
              S  K   +  ++ + ++              + +Q  + S   P+ V+AAT   +   
Sbjct: 813  LSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLS-SAPKPVAAATPVSQQAE 871

Query: 1179 EQGTSTVDQNFGKQDATVQTERGSGEKPVSAPGDDTESLHSQGEEEFDMPQ 1229
            E  T   D           T+  S  KPV+A       +  Q EE   +PQ
Sbjct: 872  EGLTLPQDSAMTPPLPLQDTDLSSAPKPVAA----ATPVSQQAEEGLTLPQ 918


>gi|41281453 serine/threonine kinase 2 [Homo sapiens]
          Length = 1235

 Score = 48.5 bits (114), Expect = 6e-05
 Identities = 99/527 (18%), Positives = 198/527 (37%), Gaps = 128/527 (24%)

Query: 447 SLPIPSQPQFSHDIFIPS-------------PSLEEQSNDGKKDGDMHSSSLTVECSKTS 493
           SLPIP+  + S D+ I S              S+ E++     +  ++S  L     K +
Sbjct: 330 SLPIPASKRASSDLSIASSEEDKLSQNACILESVSEKTERSNSEDKLNSKILN---EKPT 386

Query: 494 EIEPKNSPEDLGLSLTGDSCKLM---------LSTSEYSQSPKMESLSS---------HR 535
             EP+ + ED+   +T    + M         +  +E  + PK+E+L           + 
Sbjct: 387 TDEPEKAVEDINEHITDAQLEAMTELHDRTAVIKENEREKRPKLENLPDTEDQETVDINS 446

Query: 536 IDEDGEN---------------TQIEDTEPMSPVLNSKFVPAE--NDSILMN-------- 570
           + E  EN               ++ E  +    +  +K + +E   D+IL          
Sbjct: 447 VSEGKENNIMITLETNIEHNLKSEEEKDQEKQQMFENKLIKSEEIKDTILQTVDLVSQET 506

Query: 571 -------PAQDGEVQLSQNDDKTK-GDDTDTRDDI----SILATGCKGRE--ETVAEDVC 616
                   A D EV L++ D + K G+D  T+ D+    S +   C+  +  + V ED  
Sbjct: 507 GEKEANIQAVDSEVGLTKEDTQEKLGEDDKTQKDVISNTSDVIGTCEAADVAQKVDEDSA 566

Query: 617 IDLTCDSGSQAV--------------PSPATRSEALSSVLDQEEAMEIKEHHPEEGSSGS 662
            D   + G + V               +  T+   +  +++  E  E K       SS  
Sbjct: 567 EDTQSNDGKEVVEVGQKLINKPMVGPEAGGTKEVPIKEIVEMNEIEEGKNKEQAINSS-E 625

Query: 663 EVEEIPETPCESQGEELKE-ENMESVPLHLSLTETQSQGLCLQKEMPKKECSEAMEVETS 721
            + +I E P  ++GEE+ E  + E + +   + +T  + L         E  +A +V T 
Sbjct: 626 NIMDINEEPGTTEGEEITESSSTEEMEVRSVVADTDQKAL-------GSEVQDASKVTT- 677

Query: 722 VISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPS----PRVDVSCEPLEG 777
                          +++ +++E       E    V+    EP     P ++++ +  E 
Sbjct: 678 ---------------QIDKEKKEIPVSIKKEPEVTVVSQPTEPQPVLIPSININSDSGEN 722

Query: 778 VEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPS-LP 836
            E+       E I P   P +EN  +   +            TA+T  ++ + S  S L 
Sbjct: 723 KEEIGSLSKTETILP---PESENPKENDNDSGT-------GSTADTSSIDLNLSISSFLS 772

Query: 837 LVRADDPLRLDQELQQPQTQEKTSNSLTEDSKMA-NAKQLSSDAEAQ 882
             +    + L +  +Q +T +KT   + +  +++    ++ +D++++
Sbjct: 773 KTKDSGSISLQETRRQKKTLKKTRKFIVDGVEVSVTTSKIVTDSDSK 819



 Score = 39.7 bits (91), Expect = 0.029
 Identities = 94/530 (17%), Positives = 197/530 (37%), Gaps = 61/530 (11%)

Query: 41  SMLSRHLPNLQTHKENPVLDVVSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDT 100
           S L +H P +      P+ ++++  +    EE  DG     E   EN +  P        
Sbjct: 284 SQLLQH-PFVTVDSNKPIRELIAEAKAEVTEEVEDGKEEDEEEETENSLPIPASKRASSD 342

Query: 101 CGSISQVIEQLPQPNRTSSVLGMSVESAPAVEEEKGEELEQK--EKEKEEDTSGNTTHSL 158
               S   ++L Q       +    E + + ++   + L +K    E E+       H  
Sbjct: 343 LSIASSEEDKLSQNACILESVSEKTERSNSEDKLNSKILNEKPTTDEPEKAVEDINEHIT 402

Query: 159 GAEDTASSQLGFGVLELSQSQDVEENTVPYEVDKEQLQSVTTNS---GYTRLSDVDANTA 215
            A+  A ++L      + +++  +   +    D E  ++V  NS   G      +   T 
Sbjct: 403 DAQLEAMTELHDRTAVIKENEREKRPKLENLPDTEDQETVDINSVSEGKENNIMITLETN 462

Query: 216 IKHEEQSNEDIPIAEQSS-KDIPVTAQPSKD-----VHVVKEQNPPPARSEDMPFSPKAS 269
           I+H  +S E+    +Q   ++  + ++  KD     V +V ++              +A+
Sbjct: 463 IEHNLKSEEEKDQEKQQMFENKLIKSEEIKDTILQTVDLVSQETG----------EKEAN 512

Query: 270 VAAMEAKEQLSAQELMESGLQIQKSPEPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGC 329
           + A++++  L+ ++  E      K  E +   TQ+D+   ++  + +   +  +++    
Sbjct: 513 IQAVDSEVGLTKEDTQE------KLGEDD--KTQKDVISNTSDVIGTCEAADVAQKVDED 564

Query: 330 SLASTPATTLHLLQLSGQRSLVQDSLSTNSSDLVAPSPDAFRSTPF--IVPSSPTEQEGR 387
           S   T        Q +  + +V+      +  +V P     +  P   IV  +  E+   
Sbjct: 565 SAEDT--------QSNDGKEVVEVGQKLINKPMVGPEAGGTKEVPIKEIVEMNEIEEGKN 616

Query: 388 QDKPMDTS-----VLSEEGGEPFQKKLQSGEPVELE---------NPPLLPESTVSPQAS 433
           +++ +++S     +  E G    ++  +S    E+E            L  E   + + +
Sbjct: 617 KEQAINSSENIMDINEEPGTTEGEEITESSSTEEMEVRSVVADTDQKALGSEVQDASKVT 676

Query: 434 TPISQSTPVFPPG-----SLPIPSQPQFSHDIFIPSPSLEEQSNDGKKDGDMHSSSLTVE 488
           T I +     P        + + SQP     + IPS ++   S + K+  ++ S S T  
Sbjct: 677 TQIDKEKKEIPVSIKKEPEVTVVSQPTEPQPVLIPSININSDSGENKE--EIGSLSKTET 734

Query: 489 CSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEYSQSPKMESLSSHRIDE 538
                   PK +  D G   T D+  + L+ S  S   K +   S  + E
Sbjct: 735 ILPPESENPKENDNDSGTGSTADTSSIDLNLSISSFLSKTKDSGSISLQE 784


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 97/450 (21%), Positives = 164/450 (36%), Gaps = 80/450 (17%)

Query: 108  IEQLPQPNRTSSVLGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQ 167
            +++   P+ TSS     +  + +V+EE     E+ E+E++ D + +T   L   D     
Sbjct: 964  VKRKEPPDTTSSGDQKRLRPSTSVDEED----EESERERDRDMA-DTPCELAKRDPK--- 1015

Query: 168  LGFGV-------LEL-SQSQDVEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHE 219
             G GV       LEL S  ++ E+ ++  E +  + +            D D +      
Sbjct: 1016 -GVGVRRRPARPLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDES 1074

Query: 220  EQSNEDIPIAEQSSKDIPVTAQPSKDVHVVKEQNPPPARSE-----DMPFSPKASVAAME 274
            E  +ED  ++E S KD    +   + V +V  +    + SE     +   S ++S ++ E
Sbjct: 1075 ENDDEDTALSEASEKD-EGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSE 1133

Query: 275  AKEQLSAQELMESGLQIQKSPEPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLAST 334
             +E++ A+E  E         E E +  +E +     +    DG       E        
Sbjct: 1134 DEEEVVAREEEEE-------EEEEEMVAEESMASAGPEDFEQDG-------EEAALAPGA 1179

Query: 335  PATTLHLLQLSGQRSLVQDSLSTNSSDLVAPS--PDAFRSTPFIVPSSPTEQEGRQDKPM 392
            PA            SL  +      ++ VAP   P      P  V     E+     +P 
Sbjct: 1180 PAVD----------SLGMEEEVDIETEAVAPEERPSMLDEPPLPVG---VEEPADSREPP 1226

Query: 393  DTSVLSEEGG-----EPFQKKLQSGEPVELEN-----------PPLLPESTVSPQASTPI 436
            +   LS+EG      EP  K++++  P+  E            PP++    + P    P+
Sbjct: 1227 EEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQP----PL 1282

Query: 437  SQSTPVFPPGSLPIPSQPQFSHDIFIPSPSLEEQSNDGKKDGDMHSSSLTVECSKTSEIE 496
                P  PP   P P     SH    P P  E        D   H+  L    +K+   E
Sbjct: 1283 PPPRPPRPPSPPPEPETTDASHPSVPPEPLAE--------DHPPHTPGLCGSLAKSQSTE 1334

Query: 497  PKNSPEDLGLSLTGDSCKLMLSTSEYSQSP 526
               +       L+G S  L LS+ +   SP
Sbjct: 1335 TVPATPGGEPPLSGGSSGLSLSSPQVPGSP 1364



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 42/181 (23%), Positives = 72/181 (39%), Gaps = 12/181 (6%)

Query: 651  KEHHPEEGSSGSEVEEIPETPCESQGEELKEE---NMESVPLHLSLTETQSQGLCLQKEM 707
            ++  P+  SSG +    P T  + + EE + E   +M   P  L+  + +  G+  +   
Sbjct: 966  RKEPPDTTSSGDQKRLRPSTSVDEEDEESERERDRDMADTPCELAKRDPKGVGVRRRPAR 1025

Query: 708  PKKECSEAMEVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPR 767
            P +  S   E E   +S +         QE   +E+EA EE   ED      D ++ S  
Sbjct: 1026 PLELDSGGEEDEKESLSEE---------QESTEEEEEAEEEEEEEDDDDDDSDDRDESEN 1076

Query: 768  VDVSCEPLEGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVE 827
             D      E  EK       E+    +   AE    ++  +S E+E   +S  + +E  E
Sbjct: 1077 DDEDTALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEE 1136

Query: 828  Q 828
            +
Sbjct: 1137 E 1137



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 106/516 (20%), Positives = 177/516 (34%), Gaps = 107/516 (20%)

Query: 6    SQLDSDFSQQDTPCLIIEDS-------QPESQVLEDDSGSHFSMLSRHLPNLQTHKENPV 58
            S+ + D    DTPC + +         +  ++ LE DSG             ++ +E   
Sbjct: 994  SERERDRDMADTPCELAKRDPKGVGVRRRPARPLELDSGGEEDEKESLSEEQESTEEEEE 1053

Query: 59   LDVVSNPEQTAGEERGDGNSGFNEH----LKENKVADPVDSSNLDTCGSISQVIEQLPQP 114
             +     E    ++  D +   N+     L E    D  DS   +T   ++   E     
Sbjct: 1054 AEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEEETVSIVTSKAEATSSS 1113

Query: 115  NRT-SSVLGMSVESAPAVEEEKGEELEQKEKEKEED---TSGNTTHSLGAEDTASSQLGF 170
              + SS    S ES+P+  E++ E + ++E+E+EE+    +  +  S G ED        
Sbjct: 1114 ESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAGPEDF------- 1166

Query: 171  GVLELSQSQDVEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAE 230
                    QD EE  +              + G     D++       E  S  D P   
Sbjct: 1167 -------EQDGEEAALAPGA------PAVDSLGMEEEVDIETEAVAPEERPSMLDEP--- 1210

Query: 231  QSSKDIPVTAQPSKDVHVVKEQNPPPARSEDMPFSPKASVAAMEAKEQLSAQELMESGLQ 290
                 +PV  +   D     E+ P  ++   M  SP+     +EA+  LS +   E  L+
Sbjct: 1211 ----PLPVGVEEPADSREPPEE-PGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLE 1265

Query: 291  IQ------------------KSPEPEVLSTQEDLFDQSNKTVSSDG------------CS 320
            ++                  + P P     + +  D S+ +V  +             C 
Sbjct: 1266 VEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCG 1325

Query: 321  TPSREEGGCSLASTPATTLHLLQLSGQRSLVQDSLSTNSSDLVAPSPDA----------- 369
            + ++ +   ++ +TP     L   S   SL    +  +     APSP             
Sbjct: 1326 SLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGR 1385

Query: 370  -FRSTP-FIVPSS---------PTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELE 418
             F  TP F  PS          PT +   +  P+ + VL E G       L    P+ L 
Sbjct: 1386 DFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLASPVLLETG-------LPLPLPLPLP 1438

Query: 419  NPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQP 454
             P  LP + +  QA  P    TP+ P    P+ S P
Sbjct: 1439 LPLALP-AVLRAQARAP----TPLPPLLPAPLASCP 1469


>gi|239749105 PREDICTED: NAC alpha domain containing [Homo sapiens]
          Length = 1522

 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 136/625 (21%), Positives = 228/625 (36%), Gaps = 89/625 (14%)

Query: 350 LVQDSLSTNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGG----EPF 405
           L+ + LS+ +    AP P      P IV    T Q     +   T++  +EGG    +P 
Sbjct: 95  LLPEGLSSQALSTEAPLPATLE--PRIVMGEETCQALLSPRAARTALRDQEGGHASPDPP 152

Query: 406 QKKLQSGEPVELENPPLLPESTVSPQASTPISQSTPVFP---PGSLPIPSQPQFSHDIFI 462
            +    G+ + + +PP  P+S  +P  STP   +  + P   P      S+ +   D  +
Sbjct: 153 PELCSQGD-LSVPSPPPDPDSFFTPP-STPTKTTYALLPACGPHGDARDSEAEL-RDELL 209

Query: 463 PSPSLEEQSNDGKKDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSC-KLMLSTSE 521
            SP      +    DGD  +SS +   S  +  E  + P   GLS  G    +  L  + 
Sbjct: 210 DSPPASPSGSYITADGDSWASSPSCSLSLLAPAEGLDFPSGWGLSPQGSMVDERELHPAG 269

Query: 522 YSQSPKME-SLSSHRIDEDGENTQIEDTEPMS--PVLNSKFVP----------------- 561
             + P  E SLS+      G+     D + ++  P++ +  +P                 
Sbjct: 270 TPEPPSSESSLSADSSSSWGQEGHFFDLDFLANDPMIPAALLPFQGSLIFQVEAVEVTPL 329

Query: 562 ---AENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDISILATGCKGREETVA-EDVCI 617
               E +  + +P   G++     +D T      +  D+SI     +G +E  A  D   
Sbjct: 330 SPEEEEEEAVADPDPGGDLAGEGEEDSTSASFLQSLSDLSI----TEGMDEAFAFRDDTS 385

Query: 618 DLTCDSGSQAVP-------------SPATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEV 664
             + DS S +               + AT  +      ++E     K    ++G+    V
Sbjct: 386 AASSDSDSASYAEADDERLYSGEPHAQATLLQDSVQKTEEESGGGAKGLQAQDGTVSWAV 445

Query: 665 EEIPETPCE----SQGEEL-KEENMESVPLHLSLTETQSQGLC-----LQKEMPKKECSE 714
           E  P+T       SQ +EL  E   E + L    T T +         LQ E+  +   +
Sbjct: 446 EAAPQTSDRGAYLSQRQELISEVTEEGLALGQESTATVTPHTLQVAPGLQVEVATRVTPQ 505

Query: 715 AMEVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEP 774
           A E ET     DS          +    QE   E   ++S   +   K P+P+ + S   
Sbjct: 506 AGEEET-----DSTAGQESAAMAMPQPSQEGISEILGQES---VTAEKLPTPQEETSLTL 557

Query: 775 LEGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVE-QDSSQP 833
                +    +   D+    +P A   +  ++ K    +  L   +A T P+  QD+   
Sbjct: 558 CPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKE---DLTLPQDSAMTPPLPLQDTDLS 614

Query: 834 SLPLVRADDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQ 893
           S P      P+     + Q   Q +   +L +DS M     L  D E     KP A A+ 
Sbjct: 615 SAP-----KPVAAATIVSQ---QAEEGLTLPQDSVMTPPLPL-QDTELSSAPKPVAAATL 665

Query: 894 SFCESSSETPFHFTLPKEGDIIPPL 918
                S +     TLP++  + PPL
Sbjct: 666 ----VSQQAEEGLTLPQDSAMTPPL 686



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 121/642 (18%), Positives = 217/642 (33%), Gaps = 99/642 (15%)

Query: 59   LDVVSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPNRTS 118
            ++V +     AGEE  D  +G  +      +  P      +  G  S   E+LP P   +
Sbjct: 496  VEVATRVTPQAGEEETDSTAG--QESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEET 553

Query: 119  SVLGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQS 178
            S L +  +S   ++EE G +L    K      +  T     A++  +      +      
Sbjct: 554  S-LTLCPDSPQNLKEEGGLDLPSGRKP----VAAATIVPRQAKEDLTLPQDSAMTPPLPL 608

Query: 179  QDVEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPV 238
            QD + ++ P  V    + S     G T   D      +  ++      P    ++  +  
Sbjct: 609  QDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQ 668

Query: 239  TAQPSKDVHVVKEQNPP-PARSEDMPFSPK----ASVAAMEAKEQLSAQE-------LME 286
             A+    +       PP P +  D+  +PK    A++ + +A+E L+  +       L  
Sbjct: 669  QAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPL 728

Query: 287  SGLQIQKSPEPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTP----ATTLHLL 342
                +  +P+P   +T      +   T+  D   TP        L+S P    A T+   
Sbjct: 729  QDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQ 788

Query: 343  QLSGQRSLVQDSLSTNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGG 402
            Q     +L QDS  T                   +P   T+           +++S++  
Sbjct: 789  QAEEGLTLPQDSAMTPP-----------------LPLQDTDLSSAPKPVAAATIVSQQAE 831

Query: 403  EPFQKKLQSGEPVELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFI 462
            E       S        PPL  + T    A  P++ +TPV                    
Sbjct: 832  EGLTLPQDSAM-----TPPLPLQDTDLSSAPKPVAAATPV-------------------- 866

Query: 463  PSPSLEEQSNDGKKDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEY 522
                  +Q+ +G     +   S         +  P + PE L ++            +E 
Sbjct: 867  -----SQQAEEGL---TLPQDSAMTAPLPLQDTGPTSGPEPLAVATP------QTLQAEA 912

Query: 523  SQSPKMESLSSHRIDEDGENTQIEDT-EPMSPVLNSKFVPAENDSILMN---PAQDGEVQ 578
              +P  E +++    E GE        E  +  L +   PA  D +  +   PA +    
Sbjct: 913  GCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTP 972

Query: 579  LSQNDDKTKGDDTDTRDDISILATGCKGREETVAE-------DVCIDLTCDSGSQAVPSP 631
             +  +D    D T   + +S L     G  E +AE       + C++    +G  A P  
Sbjct: 973  WAAQED---ADSTLGMEALS-LPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPD- 1027

Query: 632  ATRSEALSSVLDQEEAME--IKEHHPEEGSSGSEVEEIPETP 671
            + + E L     QE  ++   +EH P     G+   E+P+ P
Sbjct: 1028 SPQKETLEVENQQEGGLKPLAQEHGPRSALGGA--REVPDAP 1067



 Score = 40.0 bits (92), Expect = 0.023
 Identities = 206/1034 (19%), Positives = 350/1034 (33%), Gaps = 209/1034 (20%)

Query: 220  EQSNEDIPIAEQSSKDI-PVTAQ--PSKDVHVVKEQNPPPARSE-DMPFSPKASVAAMEA 275
            E + E + + ++S+  + P T Q  P   V V     P     E D     +++  AM  
Sbjct: 467  EVTEEGLALGQESTATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQ 526

Query: 276  KEQLSAQELM-ESGLQIQKSPEPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLAS- 333
              Q    E++ +  +  +K P P+         ++++ T+  D      +EEGG  L S 
Sbjct: 527  PSQEGISEILGQESVTAEKLPTPQ---------EETSLTLCPDSPQN-LKEEGGLDLPSG 576

Query: 334  ---TPATTLHLLQLSGQRSLVQDSLSTNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDK 390
                 A T+   Q     +L QDS  T                   +P   T+       
Sbjct: 577  RKPVAAATIVPRQAKEDLTLPQDSAMTPP-----------------LPLQDTDLSSAPKP 619

Query: 391  PMDTSVLSEEGGEPFQKKLQSGEPVELENPPLLPESTVSPQASTPISQSTPVFPPGSLPI 450
                +++S++  E       S     +  PPL  + T    A  P++ +T V       +
Sbjct: 620  VAAATIVSQQAEEGLTLPQDS-----VMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGL 674

Query: 451  PSQPQFSHDIFIPSPSLEEQSNDGKKDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTG 510
             + PQ S      +P L  Q      D D+ S+   V  +     + +      GL+L  
Sbjct: 675  -TLPQDS----AMTPPLPLQ------DTDLSSAPKPVAAATLVSQQAEE-----GLTLPQ 718

Query: 511  DSCK---LMLSTSEYSQSPKMESLSSHRIDEDGENTQIEDTEPMSPVL-------NSKFV 560
            DS     L L  ++ S +PK  + ++    +  E   +     M+P L       +S   
Sbjct: 719  DSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPK 778

Query: 561  PAENDSILMNPAQDGEVQLSQNDDKTKG---DDTDTRDDISILATGCKGREETVAEDVCI 617
            P    +I+   A++G + L Q+   T      DTD       +A         V++    
Sbjct: 779  PVAAATIVSQQAEEG-LTLPQDSAMTPPLPLQDTDLSSAPKPVAAAT-----IVSQQAEE 832

Query: 618  DLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEVEEIPETPCESQGE 677
             LT    S   P    +   LSS      A        EEG +      +P+    +   
Sbjct: 833  GLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLT------LPQDSAMTAPL 886

Query: 678  ELKEENMESVPLHLSLTETQSQGLCLQKE------------MPKKECSEAM-------EV 718
             L++    S P  L++   Q+    LQ E            M ++E  EA+       E 
Sbjct: 887  PLQDTGPTSGPEPLAVATPQT----LQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEK 942

Query: 719  ETSVISIDSPQKLAILDQELEHKEQEA---WEEATSEDSSVVIVDVKEPSPRVDVSCEPL 775
              ++ ++  P  L  + Q+      EA   W      DS++ +  +  P P      E  
Sbjct: 943  NAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGAGEEIA 1002

Query: 776  EGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSL 835
            E + +           P  E C E R  T +    +      S   ET  VE        
Sbjct: 1003 EALSR-----------PGREACLEARAHTGDGAKPD------SPQKETLEVENQQEGGLK 1045

Query: 836  PLVRADDPLR-LDQELQQPQTQEKTSNSLTEDSKMANAKQLS--SDAEAQKLGKPSAHAS 892
            PL +   P   L    + P         +++   ++ A++    S     +   PSA A+
Sbjct: 1046 PLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVAT 1105

Query: 893  QSFCESSSETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIAT 952
            ++  +S  E+                 GA   L       P   S P   S  PE     
Sbjct: 1106 EASLDSCPESS---------------VGAVSSLDRGCPDAPAPTSAPT--SQQPE----- 1143

Query: 953  SDVMSESMVETHDPILGSGKGDSG-AAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPA 1011
                         P+LG G  +     P V     L   L+ P    ++      +++P 
Sbjct: 1144 -------------PVLGLGSVEQPHEVPSV-----LGTPLLQPPENLAKGQPSTPVDRPL 1185

Query: 1012 TGERKNGSTAVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGE 1071
             G   +    +A +   P +  +   C+C+  QE+    E+PP     G+L   P   G 
Sbjct: 1186 -GPDPSAPGTLAGAALPPLEPPA--PCLCQDPQEDSVEDEEPP-----GSLGLPPPQAGV 1237

Query: 1072 EEKEKLEGDHTIRQSQQP---MKPISPVKDP-------------VSPASQKMVIQGPSSP 1115
            +         T      P   + P SP+  P             + P  Q     GP SP
Sbjct: 1238 QPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSP 1297

Query: 1116 QGEAMVT--------DVLEDQKE---GRSTNKENPSKALIERPSQNNIGIQTMECSLRVP 1164
             G   ++        D LE+      G   + ++  ++  E   Q+ +  QT++C  + P
Sbjct: 1298 AGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELDEQDILAPQTVQCPAQAP 1357

Query: 1165 -----ETVSAATQT 1173
                 ET++ A Q+
Sbjct: 1358 AGGSEETIAKAKQS 1371


>gi|239508792 PREDICTED: NAC alpha domain containing [Homo sapiens]
          Length = 1522

 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 136/625 (21%), Positives = 228/625 (36%), Gaps = 89/625 (14%)

Query: 350 LVQDSLSTNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGG----EPF 405
           L+ + LS+ +    AP P      P IV    T Q     +   T++  +EGG    +P 
Sbjct: 95  LLPEGLSSQALSTEAPLPATLE--PRIVMGEETCQALLSPRAARTALRDQEGGHASPDPP 152

Query: 406 QKKLQSGEPVELENPPLLPESTVSPQASTPISQSTPVFP---PGSLPIPSQPQFSHDIFI 462
            +    G+ + + +PP  P+S  +P  STP   +  + P   P      S+ +   D  +
Sbjct: 153 PELCSQGD-LSVPSPPPDPDSFFTPP-STPTKTTYALLPACGPHGDARDSEAEL-RDELL 209

Query: 463 PSPSLEEQSNDGKKDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSC-KLMLSTSE 521
            SP      +    DGD  +SS +   S  +  E  + P   GLS  G    +  L  + 
Sbjct: 210 DSPPASPSGSYITADGDSWASSPSCSLSLLAPAEGLDFPSGWGLSPQGSMVDERELHPAG 269

Query: 522 YSQSPKME-SLSSHRIDEDGENTQIEDTEPMS--PVLNSKFVP----------------- 561
             + P  E SLS+      G+     D + ++  P++ +  +P                 
Sbjct: 270 TPEPPSSESSLSADSSSSWGQEGHFFDLDFLANDPMIPAALLPFQGSLIFQVEAVEVTPL 329

Query: 562 ---AENDSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDISILATGCKGREETVA-EDVCI 617
               E +  + +P   G++     +D T      +  D+SI     +G +E  A  D   
Sbjct: 330 SPEEEEEEAVADPDPGGDLAGEGEEDSTSASFLQSLSDLSI----TEGMDEAFAFRDDTS 385

Query: 618 DLTCDSGSQAVP-------------SPATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEV 664
             + DS S +               + AT  +      ++E     K    ++G+    V
Sbjct: 386 AASSDSDSASYAEADDERLYSGEPHAQATLLQDSVQKTEEESGGGAKGLQAQDGTVSWAV 445

Query: 665 EEIPETPCE----SQGEEL-KEENMESVPLHLSLTETQSQGLC-----LQKEMPKKECSE 714
           E  P+T       SQ +EL  E   E + L    T T +         LQ E+  +   +
Sbjct: 446 EAAPQTSDRGAYLSQRQELISEVTEEGLALGQESTATVTPHTLQVAPGLQVEVATRVTPQ 505

Query: 715 AMEVETSVISIDSPQKLAILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEP 774
           A E ET     DS          +    QE   E   ++S   +   K P+P+ + S   
Sbjct: 506 AGEEET-----DSTAGQESAAMAMPQPSQEGISEILGQES---VTAEKLPTPQEETSLTL 557

Query: 775 LEGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVE-QDSSQP 833
                +    +   D+    +P A   +  ++ K    +  L   +A T P+  QD+   
Sbjct: 558 CPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKE---DLTLPQDSAMTPPLPLQDTDLS 614

Query: 834 SLPLVRADDPLRLDQELQQPQTQEKTSNSLTEDSKMANAKQLSSDAEAQKLGKPSAHASQ 893
           S P      P+     + Q   Q +   +L +DS M     L  D E     KP A A+ 
Sbjct: 615 SAP-----KPVAAATIVSQ---QAEEGLTLPQDSVMTPPLPL-QDTELSSAPKPVAAATL 665

Query: 894 SFCESSSETPFHFTLPKEGDIIPPL 918
                S +     TLP++  + PPL
Sbjct: 666 ----VSQQAEEGLTLPQDSAMTPPL 686



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 121/642 (18%), Positives = 217/642 (33%), Gaps = 99/642 (15%)

Query: 59   LDVVSNPEQTAGEERGDGNSGFNEHLKENKVADPVDSSNLDTCGSISQVIEQLPQPNRTS 118
            ++V +     AGEE  D  +G  +      +  P      +  G  S   E+LP P   +
Sbjct: 496  VEVATRVTPQAGEEETDSTAG--QESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEET 553

Query: 119  SVLGMSVESAPAVEEEKGEELEQKEKEKEEDTSGNTTHSLGAEDTASSQLGFGVLELSQS 178
            S L +  +S   ++EE G +L    K      +  T     A++  +      +      
Sbjct: 554  S-LTLCPDSPQNLKEEGGLDLPSGRKP----VAAATIVPRQAKEDLTLPQDSAMTPPLPL 608

Query: 179  QDVEENTVPYEVDKEQLQSVTTNSGYTRLSDVDANTAIKHEEQSNEDIPIAEQSSKDIPV 238
            QD + ++ P  V    + S     G T   D      +  ++      P    ++  +  
Sbjct: 609  QDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQ 668

Query: 239  TAQPSKDVHVVKEQNPP-PARSEDMPFSPK----ASVAAMEAKEQLSAQE-------LME 286
             A+    +       PP P +  D+  +PK    A++ + +A+E L+  +       L  
Sbjct: 669  QAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPL 728

Query: 287  SGLQIQKSPEPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLASTP----ATTLHLL 342
                +  +P+P   +T      +   T+  D   TP        L+S P    A T+   
Sbjct: 729  QDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQ 788

Query: 343  QLSGQRSLVQDSLSTNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGG 402
            Q     +L QDS  T                   +P   T+           +++S++  
Sbjct: 789  QAEEGLTLPQDSAMTPP-----------------LPLQDTDLSSAPKPVAAATIVSQQAE 831

Query: 403  EPFQKKLQSGEPVELENPPLLPESTVSPQASTPISQSTPVFPPGSLPIPSQPQFSHDIFI 462
            E       S        PPL  + T    A  P++ +TPV                    
Sbjct: 832  EGLTLPQDSAM-----TPPLPLQDTDLSSAPKPVAAATPV-------------------- 866

Query: 463  PSPSLEEQSNDGKKDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTGDSCKLMLSTSEY 522
                  +Q+ +G     +   S         +  P + PE L ++            +E 
Sbjct: 867  -----SQQAEEGL---TLPQDSAMTAPLPLQDTGPTSGPEPLAVATP------QTLQAEA 912

Query: 523  SQSPKMESLSSHRIDEDGENTQIEDT-EPMSPVLNSKFVPAENDSILMN---PAQDGEVQ 578
              +P  E +++    E GE        E  +  L +   PA  D +  +   PA +    
Sbjct: 913  GCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTP 972

Query: 579  LSQNDDKTKGDDTDTRDDISILATGCKGREETVAE-------DVCIDLTCDSGSQAVPSP 631
             +  +D    D T   + +S L     G  E +AE       + C++    +G  A P  
Sbjct: 973  WAAQED---ADSTLGMEALS-LPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPD- 1027

Query: 632  ATRSEALSSVLDQEEAME--IKEHHPEEGSSGSEVEEIPETP 671
            + + E L     QE  ++   +EH P     G+   E+P+ P
Sbjct: 1028 SPQKETLEVENQQEGGLKPLAQEHGPRSALGGA--REVPDAP 1067



 Score = 40.0 bits (92), Expect = 0.023
 Identities = 206/1034 (19%), Positives = 350/1034 (33%), Gaps = 209/1034 (20%)

Query: 220  EQSNEDIPIAEQSSKDI-PVTAQ--PSKDVHVVKEQNPPPARSE-DMPFSPKASVAAMEA 275
            E + E + + ++S+  + P T Q  P   V V     P     E D     +++  AM  
Sbjct: 467  EVTEEGLALGQESTATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQ 526

Query: 276  KEQLSAQELM-ESGLQIQKSPEPEVLSTQEDLFDQSNKTVSSDGCSTPSREEGGCSLAS- 333
              Q    E++ +  +  +K P P+         ++++ T+  D      +EEGG  L S 
Sbjct: 527  PSQEGISEILGQESVTAEKLPTPQ---------EETSLTLCPDSPQN-LKEEGGLDLPSG 576

Query: 334  ---TPATTLHLLQLSGQRSLVQDSLSTNSSDLVAPSPDAFRSTPFIVPSSPTEQEGRQDK 390
                 A T+   Q     +L QDS  T                   +P   T+       
Sbjct: 577  RKPVAAATIVPRQAKEDLTLPQDSAMTPP-----------------LPLQDTDLSSAPKP 619

Query: 391  PMDTSVLSEEGGEPFQKKLQSGEPVELENPPLLPESTVSPQASTPISQSTPVFPPGSLPI 450
                +++S++  E       S     +  PPL  + T    A  P++ +T V       +
Sbjct: 620  VAAATIVSQQAEEGLTLPQDS-----VMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGL 674

Query: 451  PSQPQFSHDIFIPSPSLEEQSNDGKKDGDMHSSSLTVECSKTSEIEPKNSPEDLGLSLTG 510
             + PQ S      +P L  Q      D D+ S+   V  +     + +      GL+L  
Sbjct: 675  -TLPQDS----AMTPPLPLQ------DTDLSSAPKPVAAATLVSQQAEE-----GLTLPQ 718

Query: 511  DSCK---LMLSTSEYSQSPKMESLSSHRIDEDGENTQIEDTEPMSPVL-------NSKFV 560
            DS     L L  ++ S +PK  + ++    +  E   +     M+P L       +S   
Sbjct: 719  DSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPK 778

Query: 561  PAENDSILMNPAQDGEVQLSQNDDKTKG---DDTDTRDDISILATGCKGREETVAEDVCI 617
            P    +I+   A++G + L Q+   T      DTD       +A         V++    
Sbjct: 779  PVAAATIVSQQAEEG-LTLPQDSAMTPPLPLQDTDLSSAPKPVAAAT-----IVSQQAEE 832

Query: 618  DLTCDSGSQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEVEEIPETPCESQGE 677
             LT    S   P    +   LSS      A        EEG +      +P+    +   
Sbjct: 833  GLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLT------LPQDSAMTAPL 886

Query: 678  ELKEENMESVPLHLSLTETQSQGLCLQKE------------MPKKECSEAM-------EV 718
             L++    S P  L++   Q+    LQ E            M ++E  EA+       E 
Sbjct: 887  PLQDTGPTSGPEPLAVATPQT----LQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEK 942

Query: 719  ETSVISIDSPQKLAILDQELEHKEQEA---WEEATSEDSSVVIVDVKEPSPRVDVSCEPL 775
              ++ ++  P  L  + Q+      EA   W      DS++ +  +  P P      E  
Sbjct: 943  NAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGAGEEIA 1002

Query: 776  EGVEKCSDSQSWEDIAPEIEPCAENRLDTKEEKSVEYEGDLKSGTAETEPVEQDSSQPSL 835
            E + +           P  E C E R  T +    +      S   ET  VE        
Sbjct: 1003 EALSR-----------PGREACLEARAHTGDGAKPD------SPQKETLEVENQQEGGLK 1045

Query: 836  PLVRADDPLR-LDQELQQPQTQEKTSNSLTEDSKMANAKQLS--SDAEAQKLGKPSAHAS 892
            PL +   P   L    + P         +++   ++ A++    S     +   PSA A+
Sbjct: 1046 PLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVAT 1105

Query: 893  QSFCESSSETPFHFTLPKEGDIIPPLTGATPPLIGHLKLEPKRHSTPIGISNYPESTIAT 952
            ++  +S  E+                 GA   L       P   S P   S  PE     
Sbjct: 1106 EASLDSCPESS---------------VGAVSSLDRGCPDAPAPTSAPT--SQQPE----- 1143

Query: 953  SDVMSESMVETHDPILGSGKGDSG-AAPDVDDKLCLRMKLVSPETEASEESLQFNLEKPA 1011
                         P+LG G  +     P V     L   L+ P    ++      +++P 
Sbjct: 1144 -------------PVLGLGSVEQPHEVPSV-----LGTPLLQPPENLAKGQPSTPVDRPL 1185

Query: 1012 TGERKNGSTAVAESVASPQKTMSVLSCICEARQENEARSEDPPTTPIRGNLLHFPSSQGE 1071
             G   +    +A +   P +  +   C+C+  QE+    E+PP     G+L   P   G 
Sbjct: 1186 -GPDPSAPGTLAGAALPPLEPPA--PCLCQDPQEDSVEDEEPP-----GSLGLPPPQAGV 1237

Query: 1072 EEKEKLEGDHTIRQSQQP---MKPISPVKDP-------------VSPASQKMVIQGPSSP 1115
            +         T      P   + P SP+  P             + P  Q     GP SP
Sbjct: 1238 QPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSP 1297

Query: 1116 QGEAMVT--------DVLEDQKE---GRSTNKENPSKALIERPSQNNIGIQTMECSLRVP 1164
             G   ++        D LE+      G   + ++  ++  E   Q+ +  QT++C  + P
Sbjct: 1298 AGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELDEQDILAPQTVQCPAQAP 1357

Query: 1165 -----ETVSAATQT 1173
                 ET++ A Q+
Sbjct: 1358 AGGSEETIAKAKQS 1371


>gi|38201621 eukaryotic translation initiation factor 4 gamma, 1
           isoform 1 [Homo sapiens]
          Length = 1599

 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 94/388 (24%), Positives = 140/388 (36%), Gaps = 71/388 (18%)

Query: 363 VAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELENPPL 422
           VAP+P      P I P    ++E +  +  D +    +GG+   +++ SG        P 
Sbjct: 158 VAPAPVLMNQPPQIAP----KRERKTIRIRDPN----QGGKDITEEIMSGARTASTPTPP 209

Query: 423 LPESTVSPQAS--TP---------------ISQSTPVFP-PGSLPIPSQPQFSHDIFIPS 464
                + PQA+  TP               I    P  P P   P  SQP        PS
Sbjct: 210 QTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPS 269

Query: 465 PSLEEQSNDGKKDGDMHSSSLTVECSKTSEIEP---------KNSPEDLGLSLTGDSCKL 515
           P LE  S        +   ++T       E  P         + SPE   L+      ++
Sbjct: 270 PVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEV 329

Query: 516 MLST----SEYSQSPKMES--LSSHRIDEDGENTQI--EDTEP---MSPVLNSKFVPAEN 564
            LS     SE+S SP      L+SH ++    N  +  ED EP    SP L         
Sbjct: 330 TLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSE 389

Query: 565 DSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDISILATGCKGREETVAEDVCIDLTCDSG 624
             + + P        +Q ++   G  +    D+S ++           E+   ++T    
Sbjct: 390 SPVPIAPT-------AQPEELLNGAPSPPAVDLSPVSE---------PEEQAKEVTASMA 433

Query: 625 SQAVPS--PATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEVEEIPETPCESQGEELKEE 682
              +PS  PAT   A S    QEE ME +E   EEG +G    E  E   E  GEEL   
Sbjct: 434 PPTIPSATPATAPSATSPA--QEEEME-EEEEEEEGEAG----EAGEAESEKGGEELLPP 486

Query: 683 NMESVPLHLSLTETQSQGLCLQKEMPKK 710
               +P +LS     +    +   +PK+
Sbjct: 487 ESTPIPANLSQNLEAAAATQVAVSVPKR 514


>gi|38201627 eukaryotic translation initiation factor 4 gamma, 1
           isoform 2 [Homo sapiens]
          Length = 1512

 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 94/388 (24%), Positives = 140/388 (36%), Gaps = 71/388 (18%)

Query: 363 VAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELENPPL 422
           VAP+P      P I P    ++E +  +  D +    +GG+   +++ SG        P 
Sbjct: 71  VAPAPVLMNQPPQIAP----KRERKTIRIRDPN----QGGKDITEEIMSGARTASTPTPP 122

Query: 423 LPESTVSPQAS--TP---------------ISQSTPVFP-PGSLPIPSQPQFSHDIFIPS 464
                + PQA+  TP               I    P  P P   P  SQP        PS
Sbjct: 123 QTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPS 182

Query: 465 PSLEEQSNDGKKDGDMHSSSLTVECSKTSEIEP---------KNSPEDLGLSLTGDSCKL 515
           P LE  S        +   ++T       E  P         + SPE   L+      ++
Sbjct: 183 PVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEV 242

Query: 516 MLST----SEYSQSPKMES--LSSHRIDEDGENTQI--EDTEP---MSPVLNSKFVPAEN 564
            LS     SE+S SP      L+SH ++    N  +  ED EP    SP L         
Sbjct: 243 TLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSE 302

Query: 565 DSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDISILATGCKGREETVAEDVCIDLTCDSG 624
             + + P        +Q ++   G  +    D+S ++           E+   ++T    
Sbjct: 303 SPVPIAPT-------AQPEELLNGAPSPPAVDLSPVSE---------PEEQAKEVTASMA 346

Query: 625 SQAVPS--PATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEVEEIPETPCESQGEELKEE 682
              +PS  PAT   A S    QEE ME +E   EEG +G    E  E   E  GEEL   
Sbjct: 347 PPTIPSATPATAPSATSPA--QEEEME-EEEEEEEGEAG----EAGEAESEKGGEELLPP 399

Query: 683 NMESVPLHLSLTETQSQGLCLQKEMPKK 710
               +P +LS     +    +   +PK+
Sbjct: 400 ESTPIPANLSQNLEAAAATQVAVSVPKR 427


>gi|38201623 eukaryotic translation initiation factor 4 gamma, 1
           isoform 1 [Homo sapiens]
          Length = 1599

 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 94/388 (24%), Positives = 140/388 (36%), Gaps = 71/388 (18%)

Query: 363 VAPSPDAFRSTPFIVPSSPTEQEGRQDKPMDTSVLSEEGGEPFQKKLQSGEPVELENPPL 422
           VAP+P      P I P    ++E +  +  D +    +GG+   +++ SG        P 
Sbjct: 158 VAPAPVLMNQPPQIAP----KRERKTIRIRDPN----QGGKDITEEIMSGARTASTPTPP 209

Query: 423 LPESTVSPQAS--TP---------------ISQSTPVFP-PGSLPIPSQPQFSHDIFIPS 464
                + PQA+  TP               I    P  P P   P  SQP        PS
Sbjct: 210 QTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPS 269

Query: 465 PSLEEQSNDGKKDGDMHSSSLTVECSKTSEIEP---------KNSPEDLGLSLTGDSCKL 515
           P LE  S        +   ++T       E  P         + SPE   L+      ++
Sbjct: 270 PVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEV 329

Query: 516 MLST----SEYSQSPKMES--LSSHRIDEDGENTQI--EDTEP---MSPVLNSKFVPAEN 564
            LS     SE+S SP      L+SH ++    N  +  ED EP    SP L         
Sbjct: 330 TLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSE 389

Query: 565 DSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDISILATGCKGREETVAEDVCIDLTCDSG 624
             + + P        +Q ++   G  +    D+S ++           E+   ++T    
Sbjct: 390 SPVPIAPT-------AQPEELLNGAPSPPAVDLSPVSE---------PEEQAKEVTASMA 433

Query: 625 SQAVPS--PATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEVEEIPETPCESQGEELKEE 682
              +PS  PAT   A S    QEE ME +E   EEG +G    E  E   E  GEEL   
Sbjct: 434 PPTIPSATPATAPSATSPA--QEEEME-EEEEEEEGEAG----EAGEAESEKGGEELLPP 486

Query: 683 NMESVPLHLSLTETQSQGLCLQKEMPKK 710
               +P +LS     +    +   +PK+
Sbjct: 487 ESTPIPANLSQNLEAAAATQVAVSVPKR 514


>gi|11968023 zinc finger protein 106 homolog [Homo sapiens]
          Length = 1883

 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 94/468 (20%), Positives = 177/468 (37%), Gaps = 91/468 (19%)

Query: 387  RQDKPMDTSVLSEEGGEPFQKKLQSGEPVELENPPLLPESTVSPQASTPISQS--TPVFP 444
            +Q   M+ S L     +  Q   ++ EP E  +P  +P S    + ++    S    + P
Sbjct: 1095 KQQITMEMSALRTHRIQILQGLQETYEPSE--HPDQVPCSLTRERRNSRSQTSIDAALLP 1152

Query: 445  PGSLPIPSQPQFSHDIFIPSPSLEEQSNDGKKDGDMHSSSLTVECSKTSEIEPKNSPEDL 504
                P+  +P  SH    PSP+              H S    + S   + EP +  +D 
Sbjct: 1153 TPFFPLFLEPPSSH--VSPSPTGASLQITTSPTFQTHGSVPAPDSSVQIKQEPMSPEQDE 1210

Query: 505  GLSLTGDSCKLMLSTSEYSQSPKMESLSSHRIDEDGENTQIEDTEPMSPVLNSKFVPAEN 564
             ++    S    +S          E L ++R        +I D+ P+ PV+ ++    E+
Sbjct: 1211 NVNAVPPSSACNVSK---------ELLEANR--------EISDSCPVYPVITARLSLPES 1253

Query: 565  DSILMNPAQDGEVQLSQNDDKTKGDDTDTRDDISILATGCKGREETVAEDVCIDLTCDSG 624
                  P+Q+ +  + Q + + + +++ +     + +   +G E T           +SG
Sbjct: 1254 TESFHEPSQELKFSVEQRNTRNR-ENSPSSQSAGLSSINKEGEEPTKG---------NSG 1303

Query: 625  SQAVPSPATRSEALSSVLDQEEAMEIKEHHPEEGSSGSEVEEIPETPCESQGEELKEENM 684
            S+A  S   R    S     E  +E + H P +          PE   ES          
Sbjct: 1304 SEACTSSFLRLSFAS-----ETPLEKEPHSPADQ---------PEQQAES---------- 1339

Query: 685  ESVPLHLSLTETQSQGLCLQKEMPKKECSEAMEV------ETSVISIDSPQKL------- 731
                   +LT  +++G   +K++ KK+   A  V      E  V+++   +K+       
Sbjct: 1340 -------TLTSAETRGSKKKKKLRKKKSLRAAHVPENSDTEQDVLTVKPVRKVKAGKLIK 1392

Query: 732  ------AILDQELEHKEQEAWEEATSEDSSVVIVDVKEPSPRVDVSCEPLEGVEKCSDSQ 785
                  +  +     +EQE+  +    DSS+ ++++  P   V V+ +  E  E+  DS 
Sbjct: 1393 GGKVTTSTWEDSRTGREQESVRDEPDSDSSLEVLEIPNPQLEV-VAIDSSESGEEKPDSP 1451

Query: 786  SWEDI--APEIEPCAENR-----LDTKEEKSVEYEGDLKSGTAETEPV 826
            S +DI  + E  P   +R     + +  E    Y+  +    AET+ V
Sbjct: 1452 SKKDIWNSTEQNPLETSRSGCDEVSSTSEIGTRYKDGIPVSVAETQTV 1499


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.307    0.126    0.354 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 86,745,933
Number of Sequences: 37866
Number of extensions: 4688803
Number of successful extensions: 23458
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 46
Number of HSP's successfully gapped in prelim test: 681
Number of HSP's that attempted gapping in prelim test: 19481
Number of HSP's gapped (non-prelim): 4287
length of query: 1972
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1855
effective length of database: 13,817,196
effective search space: 25630898580
effective search space used: 25630898580
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 70 (31.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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