Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 5032087

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5032087 splicing factor 3a, subunit 1, 120kDa isoform 1
[Homo sapiens]
         (793 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5032087 splicing factor 3a, subunit 1, 120kDa isoform 1 [Homo...  1613   0.0  
gi|53831995 splicing factor 3a, subunit 1, 120kDa isoform 2 [Hom...  1373   0.0  
gi|110349719 titin isoform N2-A [Homo sapiens]                        101   3e-21
gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Ho...    80   6e-15
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    78   3e-14
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    78   3e-14
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap...    77   8e-14
gi|146134388 YLP motif containing 1 [Homo sapiens]                     76   1e-13
gi|23111062 splicing factor, arginine/serine-rich 8 [Homo sapiens]     75   2e-13
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap...    75   2e-13
gi|160707881 formin 2 [Homo sapiens]                                   75   2e-13
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    74   4e-13
gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3 ...    72   2e-12
gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2 ...    72   2e-12
gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1 [...    72   2e-12
gi|210032580 SET domain containing 1B [Homo sapiens]                   72   2e-12
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap...    72   3e-12
gi|47132519 Ras association and pleckstrin homology domains 1 is...    72   3e-12
gi|116284392 mucin 2 precursor [Homo sapiens]                          71   3e-12
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo...    70   6e-12
gi|153792074 proline rich 12 [Homo sapiens]                            70   8e-12
gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Ho...    69   1e-11
gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Ho...    69   1e-11
gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Ho...    69   1e-11
gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Hom...    69   1e-11
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]                     69   1e-11
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]                     69   1e-11
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    69   1e-11
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]               69   2e-11
gi|7706501 WW domain binding protein 11 [Homo sapiens]                 69   2e-11

>gi|5032087 splicing factor 3a, subunit 1, 120kDa isoform 1 [Homo
           sapiens]
          Length = 793

 Score = 1613 bits (4177), Expect = 0.0
 Identities = 793/793 (100%), Positives = 793/793 (100%)

Query: 1   MPAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPPEVRNIVDKTASFV 60
           MPAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPPEVRNIVDKTASFV
Sbjct: 1   MPAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPPEVRNIVDKTASFV 60

Query: 61  ARNGPEFEARIRQNEINNPKFNFLNPNDPYHAYYRHKVSEFKEGKAQEPSAAIPKVMQQQ 120
           ARNGPEFEARIRQNEINNPKFNFLNPNDPYHAYYRHKVSEFKEGKAQEPSAAIPKVMQQQ
Sbjct: 61  ARNGPEFEARIRQNEINNPKFNFLNPNDPYHAYYRHKVSEFKEGKAQEPSAAIPKVMQQQ 120

Query: 121 QQTTQQQLPQKVQAQVIQETIVPKEPPPEFEFIADPPSISAFDLDVVKLTAQFVARNGRQ 180
           QQTTQQQLPQKVQAQVIQETIVPKEPPPEFEFIADPPSISAFDLDVVKLTAQFVARNGRQ
Sbjct: 121 QQTTQQQLPQKVQAQVIQETIVPKEPPPEFEFIADPPSISAFDLDVVKLTAQFVARNGRQ 180

Query: 181 FLTQLMQKEQRNYQFDFLRPQHSLFNYFTKLVEQYTKILIPPKGLFSKLKKEAENPREVL 240
           FLTQLMQKEQRNYQFDFLRPQHSLFNYFTKLVEQYTKILIPPKGLFSKLKKEAENPREVL
Sbjct: 181 FLTQLMQKEQRNYQFDFLRPQHSLFNYFTKLVEQYTKILIPPKGLFSKLKKEAENPREVL 240

Query: 241 DQVCYRVEWAKFQERERKKEEEEKEKERVAYAQIDWHDFVVVETVDFQPNEQGNFPPPTT 300
           DQVCYRVEWAKFQERERKKEEEEKEKERVAYAQIDWHDFVVVETVDFQPNEQGNFPPPTT
Sbjct: 241 DQVCYRVEWAKFQERERKKEEEEKEKERVAYAQIDWHDFVVVETVDFQPNEQGNFPPPTT 300

Query: 301 PEELGARILIQERYEKFGESEEVEMEVESDEEDDKQEKAEEPPSQLDQDTQVQDMDEGSD 360
           PEELGARILIQERYEKFGESEEVEMEVESDEEDDKQEKAEEPPSQLDQDTQVQDMDEGSD
Sbjct: 301 PEELGARILIQERYEKFGESEEVEMEVESDEEDDKQEKAEEPPSQLDQDTQVQDMDEGSD 360

Query: 361 DEEEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKI 420
           DEEEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKI
Sbjct: 361 DEEEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKI 420

Query: 421 PASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGVE 480
           PASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGVE
Sbjct: 421 PASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGVE 480

Query: 481 ETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKAKGLVPEDD 540
           ETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKAKGLVPEDD
Sbjct: 481 ETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKAKGLVPEDD 540

Query: 541 TKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRP 600
           TKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRP
Sbjct: 541 TKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRP 600

Query: 601 PMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAP 660
           PMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAP
Sbjct: 601 PMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAP 660

Query: 661 VPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMPEEEFLRRNKGPVSIKVQVPNMQDKTEW 720
           VPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMPEEEFLRRNKGPVSIKVQVPNMQDKTEW
Sbjct: 661 VPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMPEEEFLRRNKGPVSIKVQVPNMQDKTEW 720

Query: 721 KLNGQVLVFTLPLTDQVSVIKVKIHEATGMPAGKQKLQYEGIFIKDSNSLAYYNMANGAV 780
           KLNGQVLVFTLPLTDQVSVIKVKIHEATGMPAGKQKLQYEGIFIKDSNSLAYYNMANGAV
Sbjct: 721 KLNGQVLVFTLPLTDQVSVIKVKIHEATGMPAGKQKLQYEGIFIKDSNSLAYYNMANGAV 780

Query: 781 IHLALKERGGRKK 793
           IHLALKERGGRKK
Sbjct: 781 IHLALKERGGRKK 793


>gi|53831995 splicing factor 3a, subunit 1, 120kDa isoform 2 [Homo
           sapiens]
          Length = 728

 Score = 1373 bits (3554), Expect = 0.0
 Identities = 697/793 (87%), Positives = 710/793 (89%), Gaps = 65/793 (8%)

Query: 1   MPAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPPEVRNIVDKTASFV 60
           MPAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPPEVRNIVDKTASFV
Sbjct: 1   MPAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPPEVRNIVDKTASFV 60

Query: 61  ARNGPEFEARIRQNEINNPKFNFLNPNDPYHAYYRHKVSEFKEGKAQEPSAAIPKVMQQQ 120
           ARNGPEFEARIRQNEINNPKFNFLNPNDPYHAYYRHKVSEFKEGKAQ         + + 
Sbjct: 61  ARNGPEFEARIRQNEINNPKFNFLNPNDPYHAYYRHKVSEFKEGKAQ--------FVARN 112

Query: 121 QQTTQQQLPQKVQAQVIQETIVPKEPPPEFEFIADPPSISAFDLDVVKLTAQFVARNGRQ 180
            +    QL QK Q               +F+F+   P  S F+                 
Sbjct: 113 GRQFLTQLMQKEQRNY------------QFDFLR--PQHSLFN----------------- 141

Query: 181 FLTQLMQKEQRNYQFDFLRPQHSLFNYFTKLVEQYTKILIPPKGLFSKLKKEAENPREVL 240
           + T+L+++                   +TK       ILIPPKGLFSKLKKEAENPREVL
Sbjct: 142 YFTKLVEQ-------------------YTK-------ILIPPKGLFSKLKKEAENPREVL 175

Query: 241 DQVCYRVEWAKFQERERKKEEEEKEKERVAYAQIDWHDFVVVETVDFQPNEQGNFPPPTT 300
           DQVCYRVEWAKFQERERKKEEEEKEKERVAYAQIDWHDFVVVETVDFQPNEQGNFPPPTT
Sbjct: 176 DQVCYRVEWAKFQERERKKEEEEKEKERVAYAQIDWHDFVVVETVDFQPNEQGNFPPPTT 235

Query: 301 PEELGARILIQERYEKFGESEEVEMEVESDEEDDKQEKAEEPPSQLDQDTQVQDMDEGSD 360
           PEELGARILIQERYEKFGESEEVEMEVESDEEDDKQEKAEEPPSQLDQDTQVQDMDEGSD
Sbjct: 236 PEELGARILIQERYEKFGESEEVEMEVESDEEDDKQEKAEEPPSQLDQDTQVQDMDEGSD 295

Query: 361 DEEEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKI 420
           DEEEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKI
Sbjct: 296 DEEEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKI 355

Query: 421 PASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGVE 480
           PASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGVE
Sbjct: 356 PASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGVE 415

Query: 481 ETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKAKGLVPEDD 540
           ETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKAKGLVPEDD
Sbjct: 416 ETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKAKGLVPEDD 475

Query: 541 TKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRP 600
           TKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRP
Sbjct: 476 TKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRP 535

Query: 601 PMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAP 660
           PMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAP
Sbjct: 536 PMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAP 595

Query: 661 VPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMPEEEFLRRNKGPVSIKVQVPNMQDKTEW 720
           VPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMPEEEFLRRNKGPVSIKVQVPNMQDKTEW
Sbjct: 596 VPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMPEEEFLRRNKGPVSIKVQVPNMQDKTEW 655

Query: 721 KLNGQVLVFTLPLTDQVSVIKVKIHEATGMPAGKQKLQYEGIFIKDSNSLAYYNMANGAV 780
           KLNGQVLVFTLPLTDQVSVIKVKIHEATGMPAGKQKLQYEGIFIKDSNSLAYYNMANGAV
Sbjct: 656 KLNGQVLVFTLPLTDQVSVIKVKIHEATGMPAGKQKLQYEGIFIKDSNSLAYYNMANGAV 715

Query: 781 IHLALKERGGRKK 793
           IHLALKERGGRKK
Sbjct: 716 IHLALKERGGRKK 728


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score =  101 bits (251), Expect = 3e-21
 Identities = 173/790 (21%), Positives = 309/790 (39%), Gaps = 114/790 (14%)

Query: 7     QAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPPEV---RNIVDKTASFVARN 63
             + VPPPP VP  PK+P  EE  +       K       PPP     +  V +   FVA  
Sbjct: 9419  EEVPPPPKVPALPKKPVPEEKVAVPVPVAKKA------PPPRAEVSKKTVVEEKRFVAEE 9472

Query: 64    GPEF----EARIRQNEIN-NPKFNFLNPNDPYH-AYYRHKVSEFKEGKA-------QEPS 110
                F       + ++E++   ++++    +    + YR +  E +E          +EP 
Sbjct: 9473  KLSFAVPQRVEVTRHEVSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPE 9532

Query: 111   AAIPK----VMQQQQQTTQQQLPQKVQAQVIQETIVP---KEPPPEFEFIADPPSISAFD 163
               + +    ++ ++ +    ++ ++ + +++ +  +P   +EPPP     A  P      
Sbjct: 9533  EYVVEEKLHIISKRVEAEPAEVTERQEKKIVLKPKIPAKIEEPPP-----AKVPEAPKKI 9587

Query: 164   LDVVKLTAQFVARNGRQFLTQLMQKEQRNYQFDFLRPQHSLFN--YFTKLVEQYTKILIP 221
             +   K+ A  V +  +    ++ ++ ++      + P+          K+ E++ +I   
Sbjct: 9588  VPEKKVPAP-VPKKEKVPPPKVPEEPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQE 9646

Query: 222   PKGLFSKLKKEAENPREVLDQVCYRVEWAKFQERERKKEEEEKEKERVAYAQIDWHDFVV 281
              K L +  KKEA     V ++    V   K  + + K+EEE   K      ++   + V 
Sbjct: 9647  EKVLVAVTKKEAPPKARVPEEPKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVKEEKVS 9706

Query: 282   VETVDFQPNEQGNFPPPTTPEELGARILIQERYEKFGESEEVEMEVESDEEDDKQEKAEE 341
             +E    +P         T  EE      ++E        EE E   E +E D K+ +  E
Sbjct: 9707  IEAPKREPQP---IKEVTIMEEKERAYTLEEEAVSVQREEEYE---EYEEYDYKEFEEYE 9760

Query: 342   PPSQLDQDTQVQDMDEGSDDEEEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPL 401
             P  + DQ  + ++ +   +  EE ++    PE P+P  + P P++ +  K   P A K L
Sbjct: 9761  PTEEYDQYEEYEEREY--ERYEEHEEYITEPEKPIP--VKPVPEEPVPTKPKAPPA-KVL 9815

Query: 402   PPAPAPDEYLVSPITGE-KIPASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGL 460
               A  P+E +  PI  + K P  K+ E  +      +  E++ R    K+  ++V  P  
Sbjct: 9816  KKA-VPEEKVPVPIPKKLKPPPPKVPEEPK------KVFEEKIRISITKREKEQVTEPAA 9868

Query: 461   DIESSLKQLAERRTDIFGVEETA-------IGKKIGEEEIQKPEEKVTWDGHSGSMARTQ 513
              +    K++          +E A       + K++  EE+   EE VT            
Sbjct: 9869  KVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELEPEEVAFEEEVVTH----------- 9917

Query: 514   QAAQANITLQEQIEAIHKAKGLVPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPI 573
                     ++E+ E IH+ +  +    T+E++ P  P ++P+ P  P     +P    P+
Sbjct: 9918  ---VEEYLVEEEEEYIHEEEEFI----TEEEVVPVIPVKVPEVPRKP-----VPEEKKPV 9965

Query: 574   TSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPP 633
               VP+    PP       + VP +P+ P   V  L P       PP    P +   P+P 
Sbjct: 9966  P-VPKKKEAPP-------AKVPEVPKKPEEKVPVLIPKK---EKPPPAKVPEVPKKPVPE 10014

Query: 634   SAPPIMAPRP---PPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDS 690
                P+  P+    PP  VP       P   VP PAP     PP  + + P          
Sbjct: 10015 EKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVP--------KK 10066

Query: 691   LMPEEEFLRRNKGPVSIKVQVPNMQDKTEWKLNGQVLVFTLPLTDQVSVIKVKIHEATGM 750
             L+PEE    +   PV  KV+ P    K   K     +   LP  ++V   +  + E   +
Sbjct: 10067 LIPEE----KKPTPVPKKVEAP--PPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVL 10120

Query: 751   PAGKQKLQYE 760
             P  ++ L  E
Sbjct: 10121 PEEEEVLPEE 10130



 Score = 90.9 bits (224), Expect = 4e-18
 Identities = 191/865 (22%), Positives = 311/865 (35%), Gaps = 162/865 (18%)

Query: 5     PVQAVPPPPPVPTEPKQPTEEEA----SSKEDSAPSKPVVGI------------------ 42
             P +  PPPP VP EPK+  EE+     + +E    ++P   +                  
Sbjct: 9829  PKKLKPPPPKVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRK 9888

Query: 43    -IYPP---PEV------------RNIVDKTASFVARNGPEF----EARIRQNEINNPKFN 82
              + PP   PEV              +V     ++     E+    E  I + E+  P   
Sbjct: 9889  EVAPPVRVPEVPKELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVV-PVIP 9947

Query: 83    FLNPNDPYHAYYRHKVSEFKEGKAQEPSAAIPKVMQQQQQTTQQQLPQKVQAQVIQETIV 142
                P  P       K       K + P A +P+V ++ ++     +P+K +    +   V
Sbjct: 9948  VKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEV 10007

Query: 143   PKEPPPEFEF-IADPPSISAFDLDVVKLTAQFVARNGRQFLTQLMQKEQRNYQFDFLRPQ 201
             PK+P PE +  +  P  + A    V ++  + V    ++      +K +         P 
Sbjct: 10008 PKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPE--KKVPVPAPKKVEA--------PP 10057

Query: 202   HSLFNYFTKLVEQYTKILIPPKGLFSKLKKEAENPREVLDQVCYRVEWAKFQERERKKEE 261
               +     KL+ +  K    PK      K EA  P+    +    V  A  QE E   EE
Sbjct: 10058 AKVPEVPKKLIPEEKKPTPVPK------KVEAPPPKVPKKREPVPVPVALPQEEEVLFEE 10111

Query: 262   EEKEKERVAYAQIDWHDFVVVETVDFQPNEQGNFPP----PTTPEELGARILIQERYEKF 317
             E   +E V    +   + V+ E  +  P E+   P     P   EE+          E+F
Sbjct: 10112 EIVPEEEV----LPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEF 10167

Query: 318   GESEEVEMEVE----------------SDEEDDKQEKAEEPPSQ--------------LD 347
                EEV  EV+                ++++    +K E PP++              L 
Sbjct: 10168 VPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILP 10227

Query: 348   QDTQVQDMDEGSDDEEEG---QKVP--PPPETPMPPPLPPTPDQVIVRKDYDPKASKPLP 402
             ++ +V  ++   + EEE    +++P  PP    +    PP   +VI       K + P  
Sbjct: 10228 KEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVI-------KKAVPEA 10280

Query: 403   PAPAPDEYLVSPI-TGEKIPASKMQEHMRIGLLDPRWLEQRDRSIREKQ---SDDEVYAP 458
             P P P +    P    +KIP  K+   ++     P  + +  + + EK+      E   P
Sbjct: 10281 PTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKEAVPP 10340

Query: 459   G---------LDIESSLKQLAERRTDIFGVEETAIGKKIGEEEIQKPEEKVTWDGHSGSM 509
                       + +    + + + R ++  VE     ++I EEE     E+   +G    +
Sbjct: 10341 AKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEV--EEIPEEEEFHEVEEYFEEGEFHEV 10398

Query: 510   ARTQQAAQANITLQEQIEAIHKAKGLVPEDDTKEKIGPSKPNEIPQQPP--PPSSATNIP 567
                 +  Q  +  + ++E +H+   +   ++ +         E P+ PP  P  S   IP
Sbjct: 10399 EEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVF-------EKPKAPPKGPEISEKIIP 10451

Query: 568   SSAPPITSVPR--PPTMPPPVRTTVVSA----VPVMPRPPMASVVR-LPPGSVI------ 614
                PP   VPR  PP   P V   +V      VP  PR P   V   LPP  V+      
Sbjct: 10452 PKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVP 10511

Query: 615   --------APMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAP 666
                     AP P +  AP+  V       PP   P  PP  VP     A P   VP   P
Sbjct: 10512 VPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIP 10571

Query: 667   MPPVHPPPPMEDEP----TSKKLKTEDSLMPEEEFLRRNKGPVSIKVQVPNMQDKTEWKL 722
               P  PPP + + P      KK+       PE   +   K P + K  VP  +       
Sbjct: 10572 PKPESPPPEVPEAPKEVVPEKKVPAAPPKKPE---VTPVKVPEAPKEVVPEKKVPVPPPK 10628

Query: 723   NGQVLVFTLPLTDQVSVIKVKIHEA 747
               +V    +P   +V+V + K+ EA
Sbjct: 10629 KPEVPPTKVPEVPKVAVPEKKVPEA 10653



 Score = 89.7 bits (221), Expect = 9e-18
 Identities = 173/774 (22%), Positives = 282/774 (36%), Gaps = 126/774 (16%)

Query: 12    PPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPPEVRNIVDKTASFVARNGPEFEARI 71
             P  VP  P++P  EE   K    P K       PP +V  +  K         PE +  +
Sbjct: 9947  PVKVPEVPRKPVPEE--KKPVPVPKKKEA----PPAKVPEVPKK---------PEEKVPV 9991

Query: 72    RQNEINNPKFNFLNPNDPYHAYYRHKVSEFKEGKAQEPSAAIPKVMQQQ--QQTTQQQLP 129
                +   P    + P  P       KV      K + P A +P+V ++   ++      P
Sbjct: 9992  LIPKKEKPPPAKV-PEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAP 10050

Query: 130   QKVQAQVIQETIVPKE-------PPPEFEFIADPPSISAFDLDVVKLTAQFVARNGRQFL 182
             +KV+A   +   VPK+       P P  + +  PP       + V +           F 
Sbjct: 10051 KKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFE 10110

Query: 183   TQLMQKEQRNYQFDFLRPQHSLFNYFTKLVEQYTKIL------------IPPKGLFSKLK 230
              +++ +E+   + + + P+        +++ +  ++L            +PP+  +   +
Sbjct: 10111 EEIVPEEEVLPEEEEVLPEEE------EVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEE 10164

Query: 231   KEAENPREVLDQVCYRVEWAKFQERERKKEEEEK----EKERVAYAQIDWHDFVVVETVD 286
             +E     EVL +V  +V         +KK  E+K    +KE    A++      V E   
Sbjct: 10165 EEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRI 10224

Query: 287   FQPNEQGNFPPPTTPEELGARILIQERYEKFGESEEVEMEVESDEEDDKQEKAEEPPSQL 346
               P E+   P   T E     I  +E  E+    EEVE        +  ++   E P+ +
Sbjct: 10225 ILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPV 10284

Query: 347   DQDTQVQDMDEGSDDEEEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPA 406
              +  +           EE   VP   +   P  +P  P +V  +K   PK  + +PPA  
Sbjct: 10285 PKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPK-KEAVPPAKG 10343

Query: 407   PDEYLVSPITGEKIPASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEV---YAPGL--D 461
                     +  EK+  +  QE +    L+   +E     I E++   EV   +  G   +
Sbjct: 10344 ------RTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYFEEGEFHE 10397

Query: 462   IESSLK------------QLAERRTDIFGVEETAI---------GKKIGEEEI--QKPEE 498
             +E  +K            +   R  ++F  EE  +         G +I E+ I  +KP  
Sbjct: 10398 VEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEKIIPPKKPPT 10457

Query: 499   KVTWDGHSGSMARTQQAAQANITLQEQIEAIHKAKG--------LVPEDDTKEKIGPSKP 550
             KV         A+  +  +  I ++E++    + +         L P++   EK  P  P
Sbjct: 10458 KVV--PRKEPPAKVPEVPK-KIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPP 10514

Query: 551   NEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLPP 610
              + P+ PPP       P    P   VP PP   P V  T V  VP    P       +PP
Sbjct: 10515 AKKPEAPPP--KVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPP 10572

Query: 611   GSVIAPMPPIIHAPRINVVP------MPPSAP---PIMAPRPPPMIVPTAFVPAPP---- 657
                 +P P +  AP+  VVP       PP  P   P+  P  P  +VP   VP PP    
Sbjct: 10573 KPE-SPPPEVPEAPK-EVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKP 10630

Query: 658   -VAP---------------VPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMPEE 695
              V P               VP   P  P  PPP + +EP    L+   + + EE
Sbjct: 10631 EVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEE 10684



 Score = 74.3 bits (181), Expect = 4e-13
 Identities = 109/514 (21%), Positives = 196/514 (38%), Gaps = 75/514 (14%)

Query: 238  EVLDQVCYRVEWAKFQERERKKEEEEKEKERVAYAQIDWHDF--VVVETVDFQPNEQGNF 295
            E++D V  + E  K     RKKE + KEKE V   +   H    V +E+ + +P ++   
Sbjct: 9026 EIID-VSSKAEEVKIMTITRKKEVQ-KEKEAVYEKKQAVHKEKRVFIESFE-EPYDELEV 9082

Query: 296  PPPTTPEELGARILIQERYEKFGES-EEVEMEVESDEEDDKQEKAEEPPSQLDQDTQVQD 354
             P T P E       Q  YE+  E  EE+++E + +  ++ +E  EE     +++   + 
Sbjct: 9083 EPYTEPFE-------QPYYEEPDEDYEEIKVEAKKEVHEEWEEDFEEGQEYYERE---EG 9132

Query: 355  MDEGSDDEEEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPP--APAPDEYLV 412
             DEG ++ EE  +     +            + +  + ++ K    +P   AP P + + 
Sbjct: 9133 YDEGEEEWEEAYQEREVIQV----------QKEVYEESHERKVPAKVPEKKAPPPPKVIK 9182

Query: 413  SPITGEKIPASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSL---KQL 469
             P+  +    S+  E  ++ +   +  E   + + +K S   V    ++++      K++
Sbjct: 9183 KPVIEKIEKTSRRMEEEKVQVT--KVPEVSKKIVPQKPSRTPVQEEVIEVKVPAVHTKKM 9240

Query: 470  AERRTDIFGVEETAIGKKIGEEEIQKP---EEKVTWDGHSGSMARTQQAAQANITLQEQI 526
                  +F    T     +   E+QK    EEK+                  ++ + +++
Sbjct: 9241 VISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKI------------------HVAISKRV 9282

Query: 527  EAIHKAKGLVPEDDTKEKIGP---SKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMP 583
            E   K   L PE    E++ P    K  E P    P      +P    P+    + P  P
Sbjct: 9283 EPPPKVPEL-PEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAP 9341

Query: 584  PPVRTTVVSAVPVMPRP-PMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPR 642
            P V       VP    P P+A     PP  V      ++   +I +V     +PP   P 
Sbjct: 9342 PKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPE 9401

Query: 643  PPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDE------PTSKKLK------TEDS 690
             P   VP    P P       P P  P  P  P+ +E      P +KK        ++ +
Sbjct: 9402 IPKKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPEEKVAVPVPVAKKAPPPRAEVSKKT 9461

Query: 691  LMPEEEFLRRNK----GPVSIKVQVPNMQDKTEW 720
            ++ E+ F+   K     P  ++V    +  + EW
Sbjct: 9462 VVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEW 9495



 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 152/787 (19%), Positives = 297/787 (37%), Gaps = 113/787 (14%)

Query: 5     PVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPPEVRNIVDKTASFVARNG 64
             P +   PPP VP EPK+P  E+    +     +P+   +          +K    V +  
Sbjct: 9598  PKKEKVPPPKVPEEPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKE 9657

Query: 65    PEFEARIRQNEINNPKFNFLNPNDPYHAYYRHKVSEFKEGKAQEPSAAIPKVMQQ--QQQ 122
                +AR+              P +P  A    KV + K  + +EP A + +  ++  +++
Sbjct: 9658  APPKARV--------------PEEPKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVKEE 9703

Query: 123   TTQQQLPQKVQAQVIQETIVPKEPPPEFEFIADPPSISAFDLDVVKLTAQFVARNGRQF- 181
                 + P++ + Q I+E  + +E   E  +  +  ++S    +  +   ++  +   ++ 
Sbjct: 9704  KVSIEAPKR-EPQPIKEVTIMEE--KERAYTLEEEAVSVQREEEYEEYEEYDYKEFEEYE 9760

Query: 182   ----LTQLMQKEQRNYQ-----FDFL-------------------RPQHSLFNYFTKLVE 213
                   Q  + E+R Y+      +++                   +P+        K V 
Sbjct: 9761  PTEEYDQYEEYEEREYERYEEHEEYITEPEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVP 9820

Query: 214   QYTKILIP-PKGLFSKLKKEAENPREVLDQVCYRVEWAKFQERERKKEEEEKEKERVAYA 272
             +  K+ +P PK L     K  E P++V ++   R+   K   RE+++  E   K  +   
Sbjct: 9821  E-EKVPVPIPKKLKPPPPKVPEEPKKVFEEK-IRISITK---REKEQVTEPAAKVPMKPK 9875

Query: 273   QIDWHDFVVVETVDFQPNEQ-GNFPPPTTPEELGARILIQERYEKFGESEEVEMEVESDE 331
             ++   + V V   +  P  +    P    PEE+     +    E++   EE E   E +E
Sbjct: 9876  RVVAEEKVPVPRKEVAPPVRVPEVPKELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEE 9935

Query: 332   EDDKQEKAEEPPSQLDQDTQVQDMDEGSDDEEEGQKVPPPPETPMPPPLPPTPDQVIV-R 390
                ++E     P ++ +  +    +E        +K  PP + P  P  P     V++ +
Sbjct: 9936  FITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPK 9995

Query: 391   KDYDPKASKP-LPPAPAPDEYLVSPITGE-KIPASKMQE-------HMRIGLLDPRWLEQ 441
             K+  P A  P +P  P P+E +  P+  + + P +K+ E         ++ +  P+ +E 
Sbjct: 9996  KEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEA 10055

Query: 442   RDRSIRE--KQSDDEVYAP---GLDIESSLKQLAERRTDI------FGVEETAIGKKIGE 490
                 + E  K+   E   P      +E+   ++ ++R  +         EE    ++I  
Sbjct: 10056 PPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVP 10115

Query: 491   EEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKAKGLVPEDD---TKEKIGP 547
             EE   PEE+         +   ++       +  + E +   +  VPE++    +E++ P
Sbjct: 10116 EEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLP 10175

Query: 548   SKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVR 607
                 ++P   P P     +         +P+    PP       + VP +P+      + 
Sbjct: 10176 EVKPKVPVPAPVPEIKKKVTEKK---VVIPKKEEAPP-------AKVPEVPKKVEEKRII 10225

Query: 608   LPPGSVIAPMPPIIHAPRINVVPMP--PSAPP-------IMAPRPPPMI---VPTAFVPA 655
             LP    + P+  +   P    +     P  PP       +  PR P +I   VP A  P 
Sbjct: 10226 LPKEEEVLPV-EVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPV 10284

Query: 656   P-----PVAPVPAPAPMPPVHPP------PPMEDEPTSKKLKTEDSLMPEEEFLRRNKGP 704
             P     P A V    P   V  P      PP +     KK+  +  L+P++E +   KG 
Sbjct: 10285 PKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKEAVPPAKGR 10344

Query: 705   VSIKVQV 711
               ++ +V
Sbjct: 10345 TVLEEKV 10351



 Score = 67.0 bits (162), Expect = 6e-11
 Identities = 133/647 (20%), Positives = 230/647 (35%), Gaps = 131/647 (20%)

Query: 1     MPAGPVQAVPP---PPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPPEVRNIVDKTA 57
             +P  P  AVP    P  +P +P+ P  E   + ++  P K V       PEV  +  K  
Sbjct: 10553 VPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPV--KVP 10610

Query: 58    SFVARNGPEFEARI---RQNEINNPKFNFLNPNDPYHAYYRHKVSEFKEGKAQEPSAAIP 114
                    PE +  +   ++ E+   K     P  P  A    KV E    K + P    P
Sbjct: 10611 EAPKEVVPEKKVPVPPPKKPEVPPTKV----PEVPKVAVPEKKVPEAIPPKPESPP---P 10663

Query: 115   KVMQQQQQTTQQQLPQKV-----QAQVIQETIVPKEPPPEFEFIADPPSISAFDLDVVKL 169
             +V ++ ++   ++ P +V      A   Q T+ PK+P PE       P++ A   ++  +
Sbjct: 10664 EVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPE----KKAPAVVAKKPELPPV 10719

Query: 170   TAQFVARNGRQFLTQLMQKEQRNYQFDFLRPQHSLFNYFTKLVEQYTKILIPPKGLFSKL 229
                 V +                                 ++V +    L+ PK   +  
Sbjct: 10720 KVPEVPK---------------------------------EVVPEKKVPLVVPKKPEAPP 10746

Query: 230   KKEAENPREVLDQVCYRVEWAKFQERERKKEEEEKEKERVAYAQIDWHDFVVVETVDFQP 289
              K  E P+EV+ +   +V   K  E    K  E  +K             V+ E      
Sbjct: 10747 AKVPEVPKEVVPE--KKVAVPKKPEVPPAKVPEVPKKP------------VLEEKPAVPV 10792

Query: 290   NEQGNFPPPTTPEELGARILIQERYEKFGESEEVEMEVESDEEDDKQEKAEEPPSQLDQD 349
              E+   PPP           + E  E+    EE+  E E      ++E+ E PP  + ++
Sbjct: 10793 PERAESPPPE----------VYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEE 10842

Query: 350   TQVQDMDEGSDDEEEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDE 409
              +    +         +KVP   +   PPP  P P++VI +    P+   P PPAP  ++
Sbjct: 10843 PKKIIPE---------KKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPP-PPAPPKED 10892

Query: 410   YLVSPITGEKIPASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQL 469
                     + IP  K+ E  +               + EK     +  PG + +   K L
Sbjct: 10893 VKEKIFQLKAIPKKKVPEKPQ---------------VPEKVELTPLKVPGGE-KKVRKLL 10936

Query: 470   AERRTDIFGVEETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAI 529
              ER+ +    +E  + K +  +  ++ E KV        + + ++ A       + +E +
Sbjct: 10937 PERKPE---PKEEVVLKSVLRKRPEEEEPKV----EPKKLEKVKKPAVPEPPPPKPVEEV 10989

Query: 530   H-----KAKGLVPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPP 584
                   K +  +PE     +I P+ P   P+  P P +          + ++  PP  P 
Sbjct: 10990 EVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEA---------EVKTIKPPPVEPE 11040

Query: 585   PVRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPM 631
             P        VPV+ +   A   + P      P  PI   P+    P+
Sbjct: 11041 PTPIAAPVTVPVVGKKAEA---KAPKEEAAKPKGPIKGVPKKTPSPI 11084



 Score = 64.3 bits (155), Expect = 4e-10
 Identities = 174/839 (20%), Positives = 310/839 (36%), Gaps = 142/839 (16%)

Query: 11    PPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPPEVRNIVDKTASFVARNGPEFEAR 70
             PP  VP  PK+  E     K+   P K  V    PP + R ++++  S   R     + R
Sbjct: 10314 PPAKVPEVPKKVPE-----KKVLVPKKEAV----PPAKGRTVLEEKVSVAFRQEVVVKER 10364

Query: 71    IRQNEINNPKFNFLNPNDPYHAYYRHKVSEFKEGKAQEPSAAIP----KVMQQQQQTTQQ 126
             + + E+   +   +   + +H    +    F+EG+  E    I     +V ++ +     
Sbjct: 10365 L-ELEVVEAEVEEIPEEEEFHEVEEY----FEEGEFHEVEEFIKLEQHRVEEEHRVEKVH 10419

Query: 127   QLPQKVQAQVIQETIVPKEPP--PEFEFIADPPSISAFDLDVVKLTAQFVARNGRQFLTQ 184
             ++ +  +A+ ++    PK PP  PE      PP      +   K     V    ++ +  
Sbjct: 10420 RVIEVFEAEEVEVFEKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIV-- 10477

Query: 185   LMQKEQRNYQFDFLRPQHSLFNYFTKLVEQYTKILIPP-KGLFSKLKKEAENPREVLDQV 243
              ++++ R  +   + P         K V    K+ +PP K   +   K  E P+EV+ + 
Sbjct: 10478 -VEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEK 10536

Query: 244   CYRVEWAKFQERERKKEEEEKEKERVAYAQIDWHDFVVVETVDFQPNEQGNFPPPTTPEE 303
                V   K      K E    +   V  A +   +  V E +  +P      PPP  PE 
Sbjct: 10537 KVPVPPPK------KPEVPPTKVPEVPKAAVP--EKKVPEAIPPKPES----PPPEVPE- 10583

Query: 304   LGARILIQERYEKFGESEEVEMEV----ESDEEDDKQEKAEEPPSQLDQ--DTQVQDMDE 357
                + ++ E+       ++ E+      E+ +E   ++K   PP +  +   T+V ++ +
Sbjct: 10584 -APKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPK 10642

Query: 358   GSDDEEE-GQKVPPPPETPMPPPLPPTPDQVIVRK-------DYDPKA--------SKPL 401
              +  E++  + +PP PE+P PP +   P++V + +       + +P A         KP+
Sbjct: 10643 VAVPEKKVPEAIPPKPESP-PPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPV 10701

Query: 402   PPAPAPDEYL----VSPITGEKIPASKMQEHMRIGLLDPRWLEQRDRSIREKQSD----- 452
             P   AP        + P+   ++P   + E  ++ L+ P+  E     + E   +     
Sbjct: 10702 PEKKAPAVVAKKPELPPVKVPEVPKEVVPEK-KVPLVVPKKPEAPPAKVPEVPKEVVPEK 10760

Query: 453   -------DEVYAPGLDIESSLKQLAERRTDIFGVE--ETAIGKKIGEEEIQKPEEKVTWD 503
                     EV  P    E   K + E +  +   E  E+   +   E E   PEE++  +
Sbjct: 10761 KVAVPKKPEV-PPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPE 10819

Query: 504   GHSGSMARTQQAAQA----------NITLQEQIEAIHKAKGLVPEDDTKEKIGPSKPNEI 553
                      ++  +            I  ++++  I K +   P++   EK+   KP   
Sbjct: 10820 EEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKV-IEKPKLK 10878

Query: 554   PQQPPPPSSATN-------IPSSAPPITSVPRPPTMPPPVRTT----------VVSAVPV 596
             P+ PPPP +              A P   VP  P +P  V  T          V   +P 
Sbjct: 10879 PRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPE 10938

Query: 597   MPRPPMASVV------RLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPT 650
                 P   VV      + P        P  +   +   VP PP   P+     P +    
Sbjct: 10939 RKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRE 10998

Query: 651   AFVPAP-------PVAPVPAPAPMPPVHP------PPPMEDEPTSKKL--------KTED 689
               +P P       P  P+PAP P P          PPP+E EPT            K  +
Sbjct: 10999 RKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKAE 11058

Query: 690   SLMPEEEFLRRNKGPV-SIKVQVPNMQDKTEWKL----NGQVLVFTLPLTDQVSVIKVK 743
             +  P+EE   + KGP+  +  + P+  +    KL     G+      P T Q+  + +K
Sbjct: 11059 AKAPKEE-AAKPKGPIKGVPKKTPSPIEAERRKLRPGSGGEKPPDEAPFTYQLKAVPLK 11116



 Score = 60.5 bits (145), Expect = 6e-09
 Identities = 148/789 (18%), Positives = 270/789 (34%), Gaps = 187/789 (23%)

Query: 5    PVQAVPPPPPVPTEPKQPTEEE-----ASSKEDSAPSKPVVGIIYPPPEVRNIVDKTASF 59
            P +  PP P VP  PK+P  EE        KE +AP K       P PE +  V      
Sbjct: 9306 PKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKK 9365

Query: 60   VARNGPEFEARIRQNEINNPKFNFLNPNDPYHAYYRHKVSEFKEGKAQEPSAAIPKVMQQ 119
             A   P     +++  +   K   +   +                  + P  A+P++ ++
Sbjct: 9366 EA--PPAKVPEVQKGVVTEEKITIVTQRE------------------ESPPPAVPEIPKK 9405

Query: 120  QQQTTQQQLPQKVQAQVIQETI--VPKEPPPEFEFIADPPSISAFDLDVVKLTAQFVARN 177
            +    ++ +P+K +       +  +PK+P PE E +A P  ++              A  
Sbjct: 9406 KVPEERKPVPRKEEEVPPPPKVPALPKKPVPE-EKVAVPVPVAK------------KAPP 9452

Query: 178  GRQFLTQLMQKEQRNYQFDFLRPQHSLFNYFTKLVEQYTKILIPPKGLFSKLKKEAENPR 237
             R  +++    E++ +                 + E+     +P +   ++ +  AE   
Sbjct: 9453 PRAEVSKKTVVEEKRF-----------------VAEEKLSFAVPQRVEVTRHEVSAEE-- 9493

Query: 238  EVLDQVCYRVEWAKFQERERKKEEEEKEKERVAYAQIDWHDFVVVETVDFQPNEQGNFPP 297
                      EW+  +E E       +E+ER    + +  ++ V+E              
Sbjct: 9494 ----------EWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVME-------------- 9529

Query: 298  PTTPEELGARILIQERYEKFGESEEVEMEVESDEEDDKQEKAEEPPSQLDQDTQVQDMDE 357
               PEE     +++E+     +  E E    ++ ++ K     + P+++++    + + E
Sbjct: 9530 --EPEE----YVVEEKLHIISKRVEAEPAEVTERQEKKIVLKPKIPAKIEEPPPAK-VPE 9582

Query: 358  GSDDEEEGQKVP---PPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPA-------- 406
                    +KVP   P  E   PP +P  P + +  K   PK  K   P PA        
Sbjct: 9583 APKKIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQ 9642

Query: 407  ---PDEYLVSPITGEKIPASKMQEHMRIGL-------LDPRWLEQRDRSIRE------KQ 450
                ++ LV+    E  P +++ E  +  +       L P+  E+    + E      K+
Sbjct: 9643 ITQEEKVLVAVTKKEAPPKARVPEEPKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVKE 9702

Query: 451  SDDEVYAPGLDIESSLK-QLAERRTDIFGVEETAIGKKIGEE----------EIQKPEEK 499
                + AP  + +   +  + E +   + +EE A+  +  EE          E ++ E  
Sbjct: 9703 EKVSIEAPKREPQPIKEVTIMEEKERAYTLEEEAVSVQREEEYEEYEEYDYKEFEEYEPT 9762

Query: 500  VTWDGHSGSMARTQQAAQANITLQEQIEAIHKAKGLVPEDDTKEKIGPSKPNEIPQQPPP 559
              +D +     R  +        +E  E I + +  +P     E+  P+K    P+ PP 
Sbjct: 9763 EEYDQYEEYEEREYE------RYEEHEEYITEPEKPIPVKPVPEEPVPTK----PKAPPA 9812

Query: 560  PSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRL----------- 608
                  +P    P+  +P+    PPP        VP  P+      +R+           
Sbjct: 9813 KVLKKAVPEEKVPV-PIPKKLKPPPP-------KVPEEPKKVFEEKIRISITKREKEQVT 9864

Query: 609  PPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVP------------------- 649
             P + +   P  + A     VP    APP+  P  P  + P                   
Sbjct: 9865 EPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELEPEEVAFEEEVVTHVEEYLVE 9924

Query: 650  ---------TAFVPAPPVAPV-PAPAPMPPVHP-PPPMEDEPTSKKLKTEDSLMPEEEFL 698
                       F+    V PV P   P  P  P P   +  P  KK +   + +PE    
Sbjct: 9925 EEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKK 9984

Query: 699  RRNKGPVSI 707
               K PV I
Sbjct: 9985 PEEKVPVLI 9993



 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 137/677 (20%), Positives = 247/677 (36%), Gaps = 142/677 (20%)

Query: 2     PAGPVQAVP-PPPPVPTEPKQPTEE--EASSKEDSAPSKPVVGIIYPPPEVRNIVDKTAS 58
             P  P+   P P  PVPT+PK P  +  + +  E+  P      +  PPP+V         
Sbjct: 9789  PEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKV--------- 9839

Query: 59    FVARNGPEFEARIRQNEINNPKFNFLNPNDPYHAYYRHKVSEFKEGKAQEPSAAIPKVMQ 118
                   PE   ++ + +I                  R  +++ ++ +  EP+A +P   +
Sbjct: 9840  ------PEEPKKVFEEKI------------------RISITKREKEQVTEPAAKVPMKPK 9875

Query: 119   QQQQTTQQQLPQKVQAQVIQETIVPKEPPPEFEFIADPPSISAFDLDVVKLTAQFVARNG 178
             +     +  +P+K  A  ++   VPKE  PE           AF+ +VV    +++    
Sbjct: 9876  RVVAEEKVPVPRKEVAPPVRVPEVPKELEPE---------EVAFEEEVVTHVEEYLVEEE 9926

Query: 179   RQFLTQLMQKEQRNYQFDFLRPQHSLFNYFTKLVEQYTKILIPPKGLFSKLKKEAENPRE 238
              +++ +         + +F+  +  +     K+ E   K +   K      KK+   P  
Sbjct: 9927  EEYIHE---------EEEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPP-- 9975

Query: 239   VLDQVCYRVEWAKFQERERKKEEE------EKEKERVAYAQIDWHDFVVVETVDFQPNEQ 292
                        AK  E  +K EE+      +KEK   A           V  V  +P  +
Sbjct: 9976  -----------AKVPEVPKKPEEKVPVLIPKKEKPPPA----------KVPEVPKKPVPE 10014

Query: 293   GNFPPPTTPEELGARILIQERYEKFGESEEVEMEVESDEEDDKQEKAEEPPSQLDQDTQV 352
                P P   +       + E  +K    ++V +           +K E PP+++ +  + 
Sbjct: 10015 EKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPA--------PKKVEAPPAKVPEVPKK 10066

Query: 353   QDMDEGSDDEEEGQKVPPPPETPM---PPPLP---PTPDQVIVRKDYDPKAS-KPLPPAP 405
                +E        +   PPP+ P    P P+P   P  ++V+  ++  P+    P     
Sbjct: 10067 LIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEV 10126

Query: 406   APDEYLVSPITGEKIPASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESS 465
              P+E  V P   E +P  +         + P   E+      E   ++E + P  ++   
Sbjct: 10127 LPEEEEVLPEEEEVLPEEEE--------IPPE--EEEVPPEEEYVPEEEEFVPEEEVLPE 10176

Query: 466   LKQLAERRTDIFGVEETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQ 525
             +K        +       I KK+ E+++  P++              ++A  A +   E 
Sbjct: 10177 VKPKVPVPAPV-----PEIKKKVTEKKVVIPKK--------------EEAPPAKV--PEV 10215

Query: 526   IEAIHKAKGLVPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPP 585
              + + + + ++P++   E++ P +  E P++   P S   IP   P I  V      PP 
Sbjct: 10216 PKKVEEKRIILPKE---EEVLPVEVTEEPEE--EPISEEEIPEEPPSIEEVEE--VAPPR 10268

Query: 586   VRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPP 645
             V   +  AVP  P  P+   V  PP  V   +P      ++ V      APP   P  P 
Sbjct: 10269 VPEVIKKAVPEAP-TPVPKKVEAPPAKVSKKIP----EEKVPVPVQKKEAPPAKVPEVPK 10323

Query: 646   MIVPTAFVPAPPVAPVP 662
               VP   V  P    VP
Sbjct: 10324 K-VPEKKVLVPKKEAVP 10339



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 143/678 (21%), Positives = 244/678 (35%), Gaps = 129/678 (19%)

Query: 115  KVMQQQQQTTQQQLPQKVQAQVIQETIVPKEPPPEFEFIADPPSI-----SAFDLDVVKL 169
            +V ++  +   +++  K +    +E IV K PPP     A  P I      A ++ ++ +
Sbjct: 8983 EVTKKAVKKDAKKVVAKPKEMTPREEIVKKPPPPTTLIPAKAPEIIDVSSKAEEVKIMTI 9042

Query: 170  TAQFVARNGRQFL---TQLMQKEQRNYQFDFLRPQHSL----------FNYFTKLVEQYT 216
            T +   +  ++ +    Q + KE+R +   F  P   L            Y+ +  E Y 
Sbjct: 9043 TRKKEVQKEKEAVYEKKQAVHKEKRVFIESFEEPYDELEVEPYTEPFEQPYYEEPDEDYE 9102

Query: 217  KILIPPKGLFSKLKKEAENPREVLDQVCYRVEWAKFQERERKKEEEEKEKERVAYAQIDW 276
            +I +  K    ++ +E E   E   +   R E   + E E + EE  +E+E V   Q + 
Sbjct: 9103 EIKVEAK---KEVHEEWEEDFEEGQEYYEREE--GYDEGEEEWEEAYQERE-VIQVQKEV 9156

Query: 277  HDFVVVETVDFQPNEQGNFPPP-------------------------TTPEELGARILIQ 311
            ++      V  +  E+   PPP                         T   E+  +I+ Q
Sbjct: 9157 YEESHERKVPAKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVSKKIVPQ 9216

Query: 312  ERYEKFGESEEVEMEVE---------SDEEDDKQEKAEEPPSQLDQDTQVQDMDEGSDDE 362
            +      + E +E++V          S+E+       EE  S    + Q + + E     
Sbjct: 9217 KPSRTPVQEEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKIHV 9276

Query: 363  EEGQKVPPPPETP-----------MPPPL-----PPTPDQVIVRKDYDPKASKPLP---- 402
               ++V PPP+ P            P P+     PP P    V K   P+  KP+P    
Sbjct: 9277 AISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKK 9336

Query: 403  -PA-----------PAPDEYLVSPITGEK-IPASKMQEHMRIGLLDPRWLEQRDRSIREK 449
             PA           P P+E +  P+  +K  P +K+ E ++ G++     E++   + ++
Sbjct: 9337 EPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPE-VQKGVV----TEEKITIVTQR 9391

Query: 450  QSDDEVYAPGLDIESSLKQLAERRTDIFGVEE--------TAIGKKIGEEEIQKPEEKVT 501
            +       P    E   K++ E R  +   EE         A+ KK        PEEKV 
Sbjct: 9392 EESPPPAVP----EIPKKKVPEERKPVPRKEEEVPPPPKVPALPKK------PVPEEKVA 9441

Query: 502  WDGHSGSMARTQQAAQANITLQEQ--IEAIHKAKGLVPE--DDTKEKIGPSKPNEIPQQP 557
                    A   +A  +  T+ E+    A  K    VP+  + T+ ++   +     ++ 
Sbjct: 9442 VPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEE 9501

Query: 558  PPPSSAT--NIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIA 615
               S +              V     M  P    V   + ++ +      V   P  V  
Sbjct: 9502 EGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKR-----VEAEPAEVTE 9556

Query: 616  PM-PPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPP 674
                 I+  P+I      P  PP   P  P  IVP   VPAP       P P  P  P  
Sbjct: 9557 RQEKKIVLKPKIPAKIEEP--PPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPKK 9614

Query: 675  PM-EDEPTSKKLKTEDSL 691
            P+ E +   K +K E+ L
Sbjct: 9615 PVPEKKVPPKVIKMEEPL 9632



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 85/392 (21%), Positives = 137/392 (34%), Gaps = 82/392 (20%)

Query: 370  PPPETPMPPPLPPTPDQVIVRKDYDPKASKP--------LPPAPAPDEYLVSPITGEKIP 421
            P PE   PPP      +  V+KD     +KP        +   P P   L+     E I 
Sbjct: 8970 PTPEEKKPPPKRIEVTKKAVKKDAKKVVAKPKEMTPREEIVKKPPPPTTLIPAKAPEIID 9029

Query: 422  ASKMQEHMRIGLLDPRWLEQRDR-SIREK------------QSDDEVYAPGLDIESSLKQ 468
             S   E ++I  +  +   Q+++ ++ EK            +S +E Y   L++E   + 
Sbjct: 9030 VSSKAEEVKIMTITRKKEVQKEKEAVYEKKQAVHKEKRVFIESFEEPY-DELEVEPYTEP 9088

Query: 469  LA----ERRTDIFGVEETAIGKKIGEEEIQKPEEKVTW----DGHSGSMARTQQAAQANI 520
                  E   + +   +    K++ EE  +  EE   +    +G+       ++A Q   
Sbjct: 9089 FEQPYYEEPDEDYEEIKVEAKKEVHEEWEEDFEEGQEYYEREEGYDEGEEEWEEAYQERE 9148

Query: 521  TLQEQIEAIHKAKGLVPEDDTKEKIGPSKPNEIPQQ--PPPPS----------------- 561
             +Q Q E        V E+  + K+    P ++P++  PPPP                  
Sbjct: 9149 VIQVQKE--------VYEESHERKV----PAKVPEKKAPPPPKVIKKPVIEKIEKTSRRM 9196

Query: 562  -----SATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMA-SVVRL------- 608
                   T +P  +  I  VP+ P+  P     +   VP +    M  S  ++       
Sbjct: 9197 EEEKVQVTKVPEVSKKI--VPQKPSRTPVQEEVIEVKVPAVHTKKMVISEEKMFFASHTE 9254

Query: 609  PPGSVIAP--MPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAP 666
               SV  P     I+   +I+V       PP   P  P    P    P P    V  PAP
Sbjct: 9255 EEVSVTVPEVQKEIVTEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAP 9314

Query: 667  MPPVHPPPPMEDE----PTSKKLKTEDSLMPE 694
              P  P  P+ +E    P  KK       +PE
Sbjct: 9315 KVPEVPKKPVPEEKKPVPVPKKEPAAPPKVPE 9346



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 37/154 (24%), Positives = 59/154 (38%), Gaps = 14/154 (9%)

Query: 605  VVRLPP-GSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRP--PPMIVPTAFVPAPPVAPV 661
            + RL P G   +     +    I +   PP  P    P P  P   VP   +P     P+
Sbjct: 8906 IARLEPRGEARSTAELYLTTKEIKLELKPPDIPDSRVPIPTMPIRAVPPEEIPPVVAPPI 8965

Query: 662  PAPAPMPPVHPPPPMEDEPTSKKLKTE--------DSLMPEEEFLRRNKGPVS-IKVQVP 712
            P   P P    PPP   E T K +K +          + P EE +++   P + I  + P
Sbjct: 8966 PLLLPTPEEKKPPPKRIEVTKKAVKKDAKKVVAKPKEMTPREEIVKKPPPPTTLIPAKAP 9025

Query: 713  NMQDKTEWKLNGQVLVFTLPLTDQVSVIKVKIHE 746
             + D +      +V + T+    +V   K  ++E
Sbjct: 9026 EIIDVS--SKAEEVKIMTITRKKEVQKEKEAVYE 9057



 Score = 32.3 bits (72), Expect = 1.8
 Identities = 46/191 (24%), Positives = 76/191 (39%), Gaps = 35/191 (18%)

Query: 4     GPVQAVPPPPPVPTEPKQPTEEEASS--------KEDSAPSKPVVGIIYPPPEVRNIVDK 55
             GP+ AV P  P PT P++ T  E +         +  S    P+ G I         ++K
Sbjct: 15284 GPILAVDPLGP-PTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYI---------IEK 15333

Query: 56    TASFVARNGPEFEARIRQNEINNPKFNFLNPNDPYHAYYRHKVSEFKEGKAQEPSAAIPK 115
                    + P+FE   R N+   P  +FL  N   H  Y  +V    E    EPS  +  
Sbjct: 15334 RR----HDKPDFE---RVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNV 15386

Query: 116   VMQQQQQTTQQQLPQKVQAQVI-----QETIVPKE----PPPEFEFIADPPSISAFDLDV 166
             V+Q  +     +L   V+   I     +   +P +    P P+ E+  +   I     D 
Sbjct: 15387 VIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEK-PTDA 15445

Query: 167   VKLTAQFVARN 177
             +++T + V+R+
Sbjct: 15446 LQITKEEVSRS 15456



 Score = 31.6 bits (70), Expect = 3.0
 Identities = 31/118 (26%), Positives = 46/118 (38%), Gaps = 14/118 (11%)

Query: 552  EIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLPPG 611
            EI  +  PP    +IP S  PI ++P     P  +   V   +P++   P     + PP 
Sbjct: 8927 EIKLELKPP----DIPDSRVPIPTMPIRAVPPEEIPPVVAPPIPLLLPTPEE---KKPPP 8979

Query: 612  SVIAPMPPIIHAPRINVVPMPPSAPP--IMAPRPPPMIVPTAFVP--APPVAPVPAPA 665
              I      +      VV  P    P   +  +PPP   PT  +P  AP +  V + A
Sbjct: 8980 KRIEVTKKAVKKDAKKVVAKPKEMTPREEIVKKPPP---PTTLIPAKAPEIIDVSSKA 9034


>gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Homo
           sapiens]
          Length = 406

 Score = 80.5 bits (197), Expect = 6e-15
 Identities = 58/129 (44%), Positives = 68/129 (52%), Gaps = 27/129 (20%)

Query: 553 IPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGS 612
           +PQ P PP     +P   PP+   PRPP +P P R       P+ P PPMA V   PPGS
Sbjct: 238 VPQLPRPPV----LP--VPPMP--PRPPMVPMPPRP------PIAPMPPMAPV---PPGS 280

Query: 613 VIAPMPPIIHAPRI-NVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVH 671
            +AP+PP    PR+  V P PP AP  + P PP   VPT     PP+APVP   PM  V 
Sbjct: 281 RMAPVPP---GPRMAPVPPWPPMAP--VPPWPPMAPVPT----GPPMAPVPPGPPMARVP 331

Query: 672 PPPPMEDEP 680
           P PPM   P
Sbjct: 332 PGPPMARVP 340



 Score = 76.6 bits (187), Expect = 8e-14
 Identities = 50/134 (37%), Positives = 62/134 (46%), Gaps = 11/134 (8%)

Query: 549 KPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRL 608
           +P  +P  P PP          PPI   P PP  P P  + +    PV P P MA V   
Sbjct: 243 RPPVLPVPPMPPRPPMVPMPPRPPIA--PMPPMAPVPPGSRM---APVPPGPRMAPVPPW 297

Query: 609 PPGSVIAPMPPIIHAPR-INVVPMPPSAPPIMAPRPPPMI-VPTAFVPAPPVAPVPAPAP 666
           PP + + P PP+   P    + P+PP  P    P  PPM  VP    P PP+AP+P   P
Sbjct: 298 PPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVP----PGPPMAPLPPGPP 353

Query: 667 MPPVHPPPPMEDEP 680
           M P+ P PPM   P
Sbjct: 354 MAPLPPGPPMAPLP 367



 Score = 73.2 bits (178), Expect = 9e-13
 Identities = 47/134 (35%), Positives = 61/134 (45%), Gaps = 10/134 (7%)

Query: 547 PSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVV 606
           P +P  +P  P PP +   +P  AP        P  P P    V    P+ P PP   + 
Sbjct: 253 PPRPPMVPMPPRPPIAP--MPPMAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWPPMA 310

Query: 607 RLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAP 666
            +P G  +AP+PP    P   V P PP A   + P PP   +P    P PP+AP+P   P
Sbjct: 311 PVPTGPPMAPVPP--GPPMARVPPGPPMAR--VPPGPPMAPLP----PGPPMAPLPPGPP 362

Query: 667 MPPVHPPPPMEDEP 680
           M P+ P PPM   P
Sbjct: 363 MAPLPPGPPMAPLP 376



 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 53/147 (36%), Positives = 64/147 (43%), Gaps = 39/147 (26%)

Query: 547 PSKPNEIPQQP----PPPSSATNIPSSA--------PPITSVPR-PPTMPPPVRTTVVSA 593
           P +P   P  P    PP S    +P           PP+  VP  PP  P P   T    
Sbjct: 262 PPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVP---TGPPM 318

Query: 594 VPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFV 653
            PV P PPMA   R+PPG  +A +PP    P   + P+PP  P  MAP P          
Sbjct: 319 APVPPGPPMA---RVPPGPPMARVPP---GP--PMAPLPPGPP--MAPLP---------- 358

Query: 654 PAPPVAPVPAPAPMPPVHPPPPMEDEP 680
           P PP+AP+P   P PP+ P PP    P
Sbjct: 359 PGPPMAPLP---PGPPMAPLPPRSHVP 382



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 34/86 (39%), Positives = 41/86 (47%), Gaps = 12/86 (13%)

Query: 608 LPPGSVIAPMPPIIHAPRINVVPMPPSAP-------PIMAPRPPPMIVP--TAFVPAPP- 657
           L P   +  +P +   P + V PMPP  P       P +AP PP   VP  +   P PP 
Sbjct: 229 LDPALCVHLVPQLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPG 288

Query: 658 --VAPVPAPAPMPPVHPPPPMEDEPT 681
             +APVP   PM PV P PPM   PT
Sbjct: 289 PRMAPVPPWPPMAPVPPWPPMAPVPT 314



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 28/90 (31%), Positives = 39/90 (43%), Gaps = 5/90 (5%)

Query: 550 PNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLP 609
           P   P  P PP          PP+  VP  P M P     +    P+ P PP   +  LP
Sbjct: 313 PTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAP-----LPPGPPMAPLPPGPPMAPLP 367

Query: 610 PGSVIAPMPPIIHAPRINVVPMPPSAPPIM 639
           PG  +AP+PP  H P   + P+  +  P++
Sbjct: 368 PGPPMAPLPPRSHVPHTGLAPVHITWAPVI 397



 Score = 33.9 bits (76), Expect = 0.61
 Identities = 17/56 (30%), Positives = 24/56 (42%), Gaps = 3/56 (5%)

Query: 633 PSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVH---PPPPMEDEPTSKKL 685
           P+  P +     P +     +P PP+ P P   PMPP     P PPM   P   ++
Sbjct: 227 PALDPALCVHLVPQLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRM 282



 Score = 30.4 bits (67), Expect = 6.7
 Identities = 26/92 (28%), Positives = 34/92 (36%), Gaps = 5/92 (5%)

Query: 536 VPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVP 595
           VP       + P  P       PP +     P  AP     P  P  P P    +    P
Sbjct: 312 VPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPGPPMAPLPPGPPMAPLPPGPP 371

Query: 596 VMPRPPMASVVRLPPGSVIAPMPPIIHAPRIN 627
           + P PP + V    P + +AP+  I  AP IN
Sbjct: 372 MAPLPPRSHV----PHTGLAPV-HITWAPVIN 398



 Score = 30.0 bits (66), Expect = 8.8
 Identities = 29/122 (23%), Positives = 49/122 (40%), Gaps = 12/122 (9%)

Query: 488 IGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKAKGLVPEDD-TKEKIG 546
           +GE+  +  +EK+T           ++  ++      + E     +G VP DD  +E  G
Sbjct: 19  VGEDIEEVNDEKLTVTSLMARGGEDEENTRSKPEYGTEAENNVGTEGSVPSDDQDREGGG 78

Query: 547 PSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVM-------PR 599
             +P +  QQ  PP +        PP+  + +    PP  +TTV    P         P+
Sbjct: 79  GHEPEQ--QQEEPPLTKPEQQQEEPPLLELKQEQEEPP--QTTVEGPQPAEGPQTAEGPQ 134

Query: 600 PP 601
           PP
Sbjct: 135 PP 136


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 78.2 bits (191), Expect = 3e-14
 Identities = 45/136 (33%), Positives = 62/136 (45%), Gaps = 10/136 (7%)

Query: 547 PSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMP-----RPP 601
           P+ P   P   PPP +    P +APP+     PP  PP + T  + A+P  P     + P
Sbjct: 486 PASPPMSPSATPPPQAPP--PLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAP 543

Query: 602 MASVVRLPPGSVIAP---MPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPV 658
            +    LP   +  P    PP++ AP + V P PP++P + APR PP   P   V  P +
Sbjct: 544 FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRL 603

Query: 659 APVPAPAPMPPVHPPP 674
               AP P PP    P
Sbjct: 604 TLALAPGPPPPPSRSP 619



 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 48/141 (34%), Positives = 64/141 (45%), Gaps = 18/141 (12%)

Query: 547 PSKPNEIPQQPP--PPSSATNIPSS-------APPITSVPRPPTMPP--PVRTTVVSAVP 595
           PS P + P  PP  PP S +  P S       APP+   P PP  PP  P  T    A P
Sbjct: 444 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP 503

Query: 596 VMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVP-TAFVP 654
            +  PP+  + + PP +     PP +  P +  +P PP++ P  AP  P   +P +    
Sbjct: 504 PLAAPPL-QLAKPPPQA-----PPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLAT 557

Query: 655 APPVAPVPAPAPMPPVHPPPP 675
            PP AP    AP+  V P PP
Sbjct: 558 PPPQAPPVLAAPLLQVPPSPP 578



 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 47/142 (33%), Positives = 62/142 (43%), Gaps = 19/142 (13%)

Query: 547 PSKPNEI-------PQQPPP--PSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVM 597
           P  PN +       P  PPP  P  A   P ++PP++    PP+  PP        VP  
Sbjct: 425 PQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPS 484

Query: 598 P--RPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPA 655
           P   PPM+     PP +     PP + AP + +   PP APP +A  PP   +P+     
Sbjct: 485 PPASPPMSPSATPPPQA-----PPPLAAPPLQLAKPPPQAPPALA-TPPLQALPSPPASF 538

Query: 656 PPVAPV--PAPAPMPPVHPPPP 675
           P  AP    A  PM P+  PPP
Sbjct: 539 PGQAPFSPSASLPMSPLATPPP 560



 Score = 63.5 bits (153), Expect = 7e-10
 Identities = 40/147 (27%), Positives = 62/147 (42%), Gaps = 35/147 (23%)

Query: 559 PPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPV------MPRPPMASVVRLPPGS 612
           PPS     PS+ P + ++P PP  PP   TT + +  +      +P PP++ +   PP +
Sbjct: 342 PPS-----PSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQA 396

Query: 613 VIAPMPPIIHAPRINVVPMPPSAPP-------------------IMAPRPPPMIVPTAFV 653
                PP +  P +   P PP++PP                   + AP  PP   P    
Sbjct: 397 -----PPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAP 451

Query: 654 PAPPVAPVPAPAPMPPVHPPPPMEDEP 680
            +PP +P  +P+  PP   PP +   P
Sbjct: 452 FSPPASPPVSPSATPPSQAPPSLAAPP 478



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 43/143 (30%), Positives = 60/143 (41%), Gaps = 24/143 (16%)

Query: 547 PSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPP--PVRTTVVSAVPVMPRPPMAS 604
           PS P   P   PPP +   +  + PP+ + P PP  PP  P+ T         P+ P A 
Sbjct: 382 PSPPLS-PLATPPPQAPPAL--ALPPLQAPPSPPASPPLSPLATP-------SPQAPNAL 431

Query: 605 VVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFV-------PAPP 657
            V L       P  P + AP       PP++PP+     PP   P +         P+PP
Sbjct: 432 AVHLLQAPFSPPPSPPVQAPF-----SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP 486

Query: 658 VAPVPAPAPMPPVHPPPPMEDEP 680
            +P  +P+  PP   PPP+   P
Sbjct: 487 ASPPMSPSATPPPQAPPPLAAPP 509



 Score = 60.5 bits (145), Expect = 6e-09
 Identities = 44/143 (30%), Positives = 60/143 (41%), Gaps = 18/143 (12%)

Query: 554 PQQPP----PPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRP--------- 600
           PQ PP    PP  A   P ++PP++ +  P    P      +   P  P P         
Sbjct: 394 PQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFS 453

Query: 601 PMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAP--RPPPMIVPTAFVPAPPV 658
           P AS    P  +  +  PP + AP + V P PP A P M+P   PPP   P   + APP+
Sbjct: 454 PPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP-ASPPMSPSATPPPQAPPP--LAAPPL 510

Query: 659 APVPAPAPMPPVHPPPPMEDEPT 681
                P   PP    PP++  P+
Sbjct: 511 QLAKPPPQAPPALATPPLQALPS 533



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 58/206 (28%), Positives = 84/206 (40%), Gaps = 33/206 (16%)

Query: 506 SGSMARTQQAAQANITLQEQIEAIHKAKGLVPEDDTKEKIGPSKPNEIPQ-----QPP-- 558
           S  +A    +A         + A   +  L  +  T   + P  P+  P       PP  
Sbjct: 301 SSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPAT 360

Query: 559 PPSSATNI---PSSAPPITSVPRPPTMP---PPVRTTVVSAVPVMPRPPMASVVRLPPGS 612
           PPS AT     P+     + +P PP  P   PP +     A+P +  PP  S    PP S
Sbjct: 361 PPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPP--SPPASPPLS 418

Query: 613 VIA-PMPPIIHAPRINVVPMP---PSAPPIMAPRPPPM---IVPTAFVP--------APP 657
            +A P P   +A  ++++  P   P +PP+ AP  PP    + P+A  P        APP
Sbjct: 419 PLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPP 478

Query: 658 VAPVPAPAPMPPVHP---PPPMEDEP 680
           +   P+P   PP+ P   PPP    P
Sbjct: 479 LQVPPSPPASPPMSPSATPPPQAPPP 504



 Score = 38.5 bits (88), Expect = 0.025
 Identities = 86/377 (22%), Positives = 131/377 (34%), Gaps = 65/377 (17%)

Query: 365 GQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLP-----------PAPAPDEYLV- 412
           G   P PP +P PPP P TP  + V         KPL            P  AP      
Sbjct: 23  GLLTPRPPGSPRPPP-PVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTR 81

Query: 413 SPITGEKIPASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLK-QLAE 471
           S  T  + PAS+     R     P           +  S   V +PG    ++    L +
Sbjct: 82  SAGTSSRNPASRPPASGRGERAPPA----------KNTSPGPVSSPGRASGTTRPGPLGQ 131

Query: 472 RRTDIFGVEETAIGKKIGEEE-------IQKPEEKVTWDGHSGSMARTQQAAQANITLQE 524
           +   I   E  A GK     +        ++     T    S +MAR  +AA   + L  
Sbjct: 132 KGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPR 191

Query: 525 QIEAIHKAKGLVPEDDTKEKIGPSKPNEIPQQPPP----PSS--------ATNIPSSAPP 572
              +   A+   P +  ++ +  +  +   +  P     PS+        + ++ SSA P
Sbjct: 192 PAPS---ARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP 248

Query: 573 ITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVR----LPPGSVIAP-MPPIIHAPRIN 627
           ++S  R  + P    T    A P  P+P     +R     PP    AP + P+  +P   
Sbjct: 249 LSSPAR--SGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLAT 306

Query: 628 VVP---MPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPA--------PMPPVHPPPPM 676
             P   +   APP +   P    +        P+AP P+P+        P PP  PP   
Sbjct: 307 PSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAP-PSPSAPPSLQTLPSPPATPPSQA 365

Query: 677 EDEPTSKKLKTEDSLMP 693
                S  L+   S +P
Sbjct: 366 TTSLGSPTLQATHSFLP 382



 Score = 30.8 bits (68), Expect = 5.1
 Identities = 39/170 (22%), Positives = 56/170 (32%), Gaps = 25/170 (14%)

Query: 546 GPSKPNEIPQQPPPPSSATNI--PSSAPPIT-----SVPRPPTMPPPVRTTVVSAVPVMP 598
           G + P   P+  P  S+ T+   P+S PP +     + P   T P PV +   ++    P
Sbjct: 67  GATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP 126

Query: 599 RPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPV 658
            P     +R+     +A                 P    + A        PT   P+P +
Sbjct: 127 GPLGQKGLRISAEETVAR----------GKATEAPKRSALSAGARRDTSGPTPGTPSPAM 176

Query: 659 A--------PVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMPEEEFLRR 700
           A         V  P P P   P PP E    S    +E S        RR
Sbjct: 177 ARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR 226



 Score = 30.4 bits (67), Expect = 6.7
 Identities = 17/48 (35%), Positives = 22/48 (45%), Gaps = 2/48 (4%)

Query: 369 PP--PPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSP 414
           PP  PP +P+  P P  P+ + V     P +  P PP  AP     SP
Sbjct: 411 PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 458


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 78.2 bits (191), Expect = 3e-14
 Identities = 45/136 (33%), Positives = 62/136 (45%), Gaps = 10/136 (7%)

Query: 547 PSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMP-----RPP 601
           P+ P   P   PPP +    P +APP+     PP  PP + T  + A+P  P     + P
Sbjct: 447 PASPPMSPSATPPPQAPP--PLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAP 504

Query: 602 MASVVRLPPGSVIAP---MPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPV 658
            +    LP   +  P    PP++ AP + V P PP++P + APR PP   P   V  P +
Sbjct: 505 FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRL 564

Query: 659 APVPAPAPMPPVHPPP 674
               AP P PP    P
Sbjct: 565 TLALAPGPPPPPSRSP 580



 Score = 73.6 bits (179), Expect = 7e-13
 Identities = 54/204 (26%), Positives = 84/204 (41%), Gaps = 39/204 (19%)

Query: 506 SGSMARTQQAAQANITLQEQ--IEAIHKAKGLVPEDDTKEKIGP--SKPNEIPQQPPPPS 561
           SG  AR    A A+ +  +   ++A+   +   P  D    +GP  S P   P    PPS
Sbjct: 246 SGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPS 305

Query: 562 SATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPV------MPRPPMASVVRLPPGSVIA 615
                PS+ P + ++P PP  PP   TT + +  +      +P PP++ +   PP +   
Sbjct: 306 -----PSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQA--- 357

Query: 616 PMPPIIHAPRINVVPMPPSAPP-------------------IMAPRPPPMIVPTAFVPAP 656
             PP +  P +   P PP++PP                   + AP  PP   P     +P
Sbjct: 358 --PPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP 415

Query: 657 PVAPVPAPAPMPPVHPPPPMEDEP 680
           P +P  +P+  PP   PP +   P
Sbjct: 416 PASPPVSPSATPPSQAPPSLAAPP 439



 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 48/141 (34%), Positives = 64/141 (45%), Gaps = 18/141 (12%)

Query: 547 PSKPNEIPQQPP--PPSSATNIPSS-------APPITSVPRPPTMPP--PVRTTVVSAVP 595
           PS P + P  PP  PP S +  P S       APP+   P PP  PP  P  T    A P
Sbjct: 405 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP 464

Query: 596 VMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVP-TAFVP 654
            +  PP+  + + PP +     PP +  P +  +P PP++ P  AP  P   +P +    
Sbjct: 465 PLAAPPL-QLAKPPPQA-----PPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLAT 518

Query: 655 APPVAPVPAPAPMPPVHPPPP 675
            PP AP    AP+  V P PP
Sbjct: 519 PPPQAPPVLAAPLLQVPPSPP 539



 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 47/142 (33%), Positives = 62/142 (43%), Gaps = 19/142 (13%)

Query: 547 PSKPNEI-------PQQPPP--PSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVM 597
           P  PN +       P  PPP  P  A   P ++PP++    PP+  PP        VP  
Sbjct: 386 PQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPS 445

Query: 598 P--RPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPA 655
           P   PPM+     PP +     PP + AP + +   PP APP +A  PP   +P+     
Sbjct: 446 PPASPPMSPSATPPPQA-----PPPLAAPPLQLAKPPPQAPPALA-TPPLQALPSPPASF 499

Query: 656 PPVAPV--PAPAPMPPVHPPPP 675
           P  AP    A  PM P+  PPP
Sbjct: 500 PGQAPFSPSASLPMSPLATPPP 521



 Score = 60.5 bits (145), Expect = 6e-09
 Identities = 44/143 (30%), Positives = 60/143 (41%), Gaps = 18/143 (12%)

Query: 554 PQQPP----PPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRP--------- 600
           PQ PP    PP  A   P ++PP++ +  P    P      +   P  P P         
Sbjct: 355 PQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFS 414

Query: 601 PMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAP--RPPPMIVPTAFVPAPPV 658
           P AS    P  +  +  PP + AP + V P PP A P M+P   PPP   P   + APP+
Sbjct: 415 PPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP-ASPPMSPSATPPPQAPPP--LAAPPL 471

Query: 659 APVPAPAPMPPVHPPPPMEDEPT 681
                P   PP    PP++  P+
Sbjct: 472 QLAKPPPQAPPALATPPLQALPS 494



 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 46/171 (26%), Positives = 66/171 (38%), Gaps = 25/171 (14%)

Query: 546 GPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASV 605
           GPS     P+ P  PS         P      RPP + PP R     A+  +   P+A+ 
Sbjct: 247 GPSARGT-PRAPAHPSQPK------PKGLQALRPPQVTPP-RKDAAPALGPLSSSPLATP 298

Query: 606 VRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRP---PPMIVPTAFVPAPPVAPVP 662
               P S  AP       P +  +P PP+ PP  A      P +    +F+P+PP++P+ 
Sbjct: 299 SPSAPPSPSAP-------PSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLA 351

Query: 663 APAP-------MPPVHPPPPMEDEPTSKKLKTEDSLMPEEEFLRRNKGPVS 706
            P P       +PP+  PP     P    L T     P    +   + P S
Sbjct: 352 TPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS 402



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 79/351 (22%), Positives = 120/351 (34%), Gaps = 52/351 (14%)

Query: 365 GQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASK 424
           G   P PP +P PPP P TP  + V         KPL             I G  IP S 
Sbjct: 23  GLLTPRPPGSPRPPP-PVTPAALRVLGAAGAVGRKPLAER-------AGGIGGATIPESA 74

Query: 425 MQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLK-QLAERRTDIFGVEETA 483
            +         P           +  S   V +PG    ++    L ++   I   E  A
Sbjct: 75  PRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVA 134

Query: 484 IGKKIGEEE-------IQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKAKGLV 536
            GK     +        ++     T    S +MAR  +AA   + L     +   A+   
Sbjct: 135 RGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPS---ARPRP 191

Query: 537 PEDDTKEKIGPSKPNEIPQQPPP----PSS--------ATNIPSSAPPITSVPRPPTMPP 584
           P +  ++ +  +  +   +  P     PS+        + ++ SSA P++S  R  + P 
Sbjct: 192 PTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPAR--SGPS 249

Query: 585 PVRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPM--PPSAPPIMAPR 642
              T    A P  P+P     +R          PP +  PR +  P   P S+ P+  P 
Sbjct: 250 ARGTPRAPAHPSQPKPKGLQALR----------PPQVTPPRKDAAPALGPLSSSPLATPS 299

Query: 643 PPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
           P       +  P+P   P     P PP  PP        S  L+   S +P
Sbjct: 300 P-------SAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLP 343



 Score = 31.2 bits (69), Expect = 3.9
 Identities = 30/108 (27%), Positives = 39/108 (36%), Gaps = 14/108 (12%)

Query: 562 SATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPII 621
           +A   P++  P    PRPP  P P         PV P    A++  L     +   P   
Sbjct: 12  AAARTPAARAPGLLTPRPPGSPRP-------PPPVTP----AALRVLGAAGAVGRKPLAE 60

Query: 622 HAPRINVVPMPPSAP---PIMAPRPPPMIVPTAFVPAPPVAPVPAPAP 666
            A  I    +P SAP   P    RPP         PA   +P P  +P
Sbjct: 61  RAGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSP 108



 Score = 30.4 bits (67), Expect = 6.7
 Identities = 17/48 (35%), Positives = 22/48 (45%), Gaps = 2/48 (4%)

Query: 369 PP--PPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSP 414
           PP  PP +P+  P P  P+ + V     P +  P PP  AP     SP
Sbjct: 372 PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 419


>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sapiens]
          Length = 2524

 Score = 76.6 bits (187), Expect = 8e-14
 Identities = 154/696 (22%), Positives = 245/696 (35%), Gaps = 98/696 (14%)

Query: 87   NDPYHAYYRHKVSEFKEGKAQEPSAAIPKVMQQQQQTTQQQLPQKVQAQVIQETIVPKEP 146
            N+ Y +  R   S  + GK+Q+         QQQQQ  QQQ  Q+   +  QE    KE 
Sbjct: 476  NENYKSLVRR--SYRRRGKSQQ--------QQQQQQQQQQQQQQQPMPRSSQEEKDEKEK 525

Query: 147  PPEFEFIADPPSISAFDLDVVKLTA-----------QFVARNGRQF----------LTQL 185
              E E   + P +     D++K              + VA  GR+           +T+ 
Sbjct: 526  EKEAEKEEEKPEVENDKEDLLKEKTDDTSGEDNDEKEAVASKGRKTANSQGRRKGRITRS 585

Query: 186  MQKEQRNYQFDFLRPQHSL------FNYFTKLVEQYTKILIPPKGLFSKLKKEAENPREV 239
            M  E  + +   + PQ S        N  ++  E+  ++    KGL    +  +   R V
Sbjct: 586  MANEANSEEA--ITPQQSAELASMELNESSRWTEE--EMETAKKGLLEHGRNWSAIARMV 641

Query: 240  LDQVCYRVEWAKFQERERKKEEE-------EKEKERVAYAQIDWHDFVVVETVDFQPNEQ 292
              +   + +   F  ++R+  +E       + EKER A  +         +      +E+
Sbjct: 642  GSKTVSQCKNFYFNYKKRQNLDEILQQHKLKMEKERNARRK--------KKKAPAAASEE 693

Query: 293  GNFPPPTTPEELGARILIQERYEKFGESEEVEMEVESDEEDDKQEKAEEPPSQLDQDTQV 352
              FPP    EE+ A  +     E   E+E +     S  E  + E +         DT+ 
Sbjct: 694  AAFPPVVEDEEMEASGVSGNEEEMVEEAEALHA---SGNEVPRGECSGPATVNNSSDTES 750

Query: 353  QDMDEGSDDEEEGQKVPPPPET---PMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDE 409
                     ++ GQ  P PP T     PPP PPTP    +    +P  +     AP P  
Sbjct: 751  IPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPP 810

Query: 410  YLVSPITGEKIPASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQL 469
               SP     +   + +E            E++     E+ + D   A    ++S   + 
Sbjct: 811  APPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAVDTGKAEE-PVKSECTEE 869

Query: 470  AE----RRTDIFGVEETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQ 525
            AE    +  D    E TA G  +  E+ +    + T    SG+   +  +A  +    ++
Sbjct: 870  AEEGPAKGKDAEAAEATAEG-ALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDE 928

Query: 526  IEAIHKAKGLVPEDDTKEKIGPSKPNEIPQQP-------------PPPSSATNIPSSAPP 572
             E   K + L P        G  + N  PQ+P             PP  +  + P     
Sbjct: 929  AEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRAAAIPPIVTKVHEPPREDA 988

Query: 573  ITSVPRPPTMPPPVRTTVVSAVPVMP--RPPMASVVRLPPGSVIAPMPPIIHAPRINVVP 630
              + P PP  PPP      S  P  P   P   S    PP    A  P    A       
Sbjct: 989  APTKPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQK 1048

Query: 631  MPPSAP----PIMAPRPPPMIV--------PTAFVPAPPVAPVPAPA--PMPPVHPPPPM 676
            +P   P     +  P PP  ++        P+AF  APP  P+P        PV P PP 
Sbjct: 1049 LPGDPPCWTSGLPFPVPPREVIKASPHAPDPSAFSYAPPGHPLPLGLHDTARPVLPRPPT 1108

Query: 677  EDEPTSKKLKTEDSLMPEEEFLRRNKGPVSIKVQVP 712
               P       +   + E +    ++G +S+++ VP
Sbjct: 1109 ISNPPPLISSAKHPSVLERQIGAISQG-MSVQLHVP 1143



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 103/498 (20%), Positives = 189/498 (37%), Gaps = 104/498 (20%)

Query: 179 RQFLTQLMQKEQRNYQFDFLRPQHSLFNYFTKLVEQYTKILIPPKGLFSKLKKEAENPRE 238
           RQ +    ++E+  ++  F++   + F      +E+ T   +    L+  L K+ EN + 
Sbjct: 426 RQVMNMWSEQEKETFREKFMQHPKN-FGLIASFLERKT---VAECVLYYYLTKKNENYKS 481

Query: 239 VLDQVCYRVEWAKFQERERKKEEEEKEKERVAYAQIDWHDFVVVETVDFQPNEQGNFPPP 298
           ++ +         ++ R + ++++++++++                   Q  +Q    P 
Sbjct: 482 LVRR--------SYRRRGKSQQQQQQQQQQ-------------------QQQQQQQPMPR 514

Query: 299 TTPEELGARILIQERYEKFGESEEVEMEVESDEEDDKQEKAEEPPSQLDQDTQVQDMDEG 358
           ++ EE       ++  EK  E EE + EVE+D+ED  +EK +        DT  +D DE 
Sbjct: 515 SSQEEKD-----EKEKEKEAEKEEEKPEVENDKEDLLKEKTD--------DTSGEDNDEK 561

Query: 359 SDDEEEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGE 418
                +G+K                 ++    +   P+ S  L      +    S  T E
Sbjct: 562 EAVASKGRKTANSQGRRKGRITRSMANEANSEEAITPQQSAELASMELNES---SRWTEE 618

Query: 419 KIPASK--MQEHMRIGLLDPRWLEQRDRS--------IREKQSDDEV---YAPGLDIESS 465
           ++  +K  + EH R      R +  +  S         +++Q+ DE+   +   ++ E +
Sbjct: 619 EMETAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQNLDEILQQHKLKMEKERN 678

Query: 466 LKQLAERRTDIFGVEETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQ 525
            ++  +++      EE A    + +EE++         G SG+             + E+
Sbjct: 679 ARR-KKKKAPAAASEEAAFPPVVEDEEMEA-------SGVSGNEEE----------MVEE 720

Query: 526 IEAIHKAKGLVPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPP 585
            EA+H +   VP  +     GP+  N         S   +IPS   P T   +      P
Sbjct: 721 AEALHASGNEVPRGECS---GPATVNN-------SSDTESIPS---PHTEAAKDTGQNGP 767

Query: 586 VRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPP 645
                + A    P PP       PP  + AP  P   A      P PP APP  +P  PP
Sbjct: 768 KPPATLGADGPPPGPPTP-----PPEDIPAPTEP-TPASEATGAPTPPPAPP--SPSAPP 819

Query: 646 MIVP-----TAFVPAPPV 658
            +VP          APPV
Sbjct: 820 PVVPKEEKEEETAAAPPV 837



 Score = 37.4 bits (85), Expect = 0.055
 Identities = 78/354 (22%), Positives = 122/354 (34%), Gaps = 83/354 (23%)

Query: 372  PETP-MPPPLPPTPDQVIVRKDYDPKASKPL-------PPAPAPDEYLVSPITGEKIPAS 423
            P  P + PP P TP   + R  Y P A +P        P +P    +L  P T     +S
Sbjct: 1745 PHLPVLVPPTPGTPATAMDRLAYLPTAPQPFSSRHSSSPLSPGGPTHLTKPTT----TSS 1800

Query: 424  KMQEHMRIGLLDPRWLEQRDRSIREKQSDDE---VYAPGLDIESSLKQLAERRTDIFGVE 480
              +E  R    D     +R++SI    +  E   ++ PG +  S             G  
Sbjct: 1801 SERERDRDRERDRD--REREKSILTSTTTVEHAPIWRPGTEQSS-------------GSS 1845

Query: 481  ETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKA--KGLVPE 538
             ++ G   G     +P        HS    RTQ A      LQ++   +H    KG++  
Sbjct: 1846 GSSGG---GGGSSSRPASHSHAHQHSPISPRTQDA------LQQRPSVLHNTGMKGIITA 1896

Query: 539  DDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVM- 597
                             +P  P+   +  +S+P   +   PP    P+  T+    P + 
Sbjct: 1897 ----------------VEPSTPTVLRSTSTSSPVRPAATFPPATHCPLGGTLDGVYPTLM 1940

Query: 598  ---------PRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIV 648
                     PR       R   G      PP           + P++ P     P P++ 
Sbjct: 1941 EPVLLPKEAPRVARPERPRADTGHAFLAKPPARSG-------LEPASSPSKGSEPRPLVP 1993

Query: 649  PT------AFVPAPPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMPEEE 696
            P       A  PA  +AP  A +P PP   PP    +P  +K +++   + E E
Sbjct: 1994 PVSGHATIARTPAKNLAPHHA-SPDPPA--PPASASDPHREKTQSKPFSIQELE 2044



 Score = 30.4 bits (67), Expect = 6.7
 Identities = 19/81 (23%), Positives = 35/81 (43%), Gaps = 2/81 (2%)

Query: 319 ESEEVEMEVESDEEDDKQEKAEEPPSQLDQDTQVQDMDEGSDDEEEGQKVPPPPETPMPP 378
           E E V   +  +E     ++ +   + ++Q  Q+  + +     EE    PP PE P+ P
Sbjct: 159 ELELVPPRLSKEELIQNMDRVDREITMVEQ--QISKLKKKQQQLEEEAAKPPEPEKPVSP 216

Query: 379 PLPPTPDQVIVRKDYDPKASK 399
           P   +  + +V+  YD    K
Sbjct: 217 PPIESKHRSLVQIIYDENRKK 237



 Score = 30.0 bits (66), Expect = 8.8
 Identities = 17/48 (35%), Positives = 19/48 (39%), Gaps = 4/48 (8%)

Query: 2   PAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPPEV 49
           P GP    P   P PTEP   +E   +     AP  P      PPP V
Sbjct: 779 PPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSA----PPPVV 822


>gi|146134388 YLP motif containing 1 [Homo sapiens]
          Length = 2146

 Score = 75.9 bits (185), Expect = 1e-13
 Identities = 91/387 (23%), Positives = 147/387 (37%), Gaps = 76/387 (19%)

Query: 339 AEEPPSQLDQDTQVQDMDEGSDDEEEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKAS 398
           A++ P  + ++  V    +  +     +   PPP   +PPPLPP   Q       DP+  
Sbjct: 323 AKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPLPPEEPQ-----SEDPEED 377

Query: 399 KPLPPAPAPDEYLVSPITGEKIPASKMQEHM--RIGLLDPRWLEQRDRSIREKQSDDEVY 456
             L    A               A+  Q+H   R+G      +++  +  +  Q   ++ 
Sbjct: 378 ARLKQLQAA--------------AAHWQQHQQHRVGFQYQGIMQKHTQLQQILQQYQQII 423

Query: 457 APGLDIESSLKQLAERRTDI---------------FGVEETAIGKKIGEEEIQKPEEK-V 500
            P   I++    +  R  ++               F + E  +     ++++Q+ E++  
Sbjct: 424 QPPPHIQTMSVDMQLRHYEMQQQQFQHLYQEWEREFQLWEEQLHSYPHKDQLQEYEKQWK 483

Query: 501 TWDGHSGSMARTQQAAQANITLQEQIEAIHKAKG-----------LVPEDDTKEKIGPSK 549
           TW GH   M  TQ        LQE++ +    K             VP       +    
Sbjct: 484 TWQGH---MKATQSY------LQEKVNSFQNMKNQYMGNMSMPPPFVPYSQMPPPLPTMP 534

Query: 550 PNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASV---- 605
           P  +P   PPP     +P++ PP   +P PP MPP + T+V    P MP P ++S     
Sbjct: 535 PPVLPPSLPPPVMPPALPATVPP-PGMP-PPVMPPSLPTSVPP--PGMP-PSLSSAGPPP 589

Query: 606 VRLPPGSVIAPMPPIIHAPRINVVPMPP--SAPPIMAPRPPPMI----VPTAFVPAPPVA 659
           V  PP    A  PP++  P ++    PP    PP+ +  PPP I    VP    P    A
Sbjct: 590 VLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPGVPQGIPPQLTAA 649

Query: 660 PVP----APAPMPPVHPPPPMEDEPTS 682
           PVP    + +   P  P P +   P S
Sbjct: 650 PVPPASSSQSSQVPEKPRPALLPTPVS 676



 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 105/437 (24%), Positives = 144/437 (32%), Gaps = 139/437 (31%)

Query: 312  ERYEKFGESEEVEMEVESDEEDDKQEKAEEPPSQLDQDTQVQ-DMDEGSD-DEEEGQKVP 369
            ER +   E    EME + D + D+  +   P    D+    + D D G   DE+E Q   
Sbjct: 1269 ERDQDMDEDYNREMERDMDRDVDRISR---PMDMYDRSLDNEWDRDYGRPLDEQESQF-- 1323

Query: 370  PPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKMQEHM 429
               + P  PPLPP                  LPP P  D Y                   
Sbjct: 1324 RERDIPSLPPLPP------------------LPPLPPLDRYR------------------ 1347

Query: 430  RIGLLDPRWLEQRDRS--------------IREKQSDDEVYAPGLD-IESSLKQLAERRT 474
                 D RW E+R+R               IRE     + +    D +   +    ER +
Sbjct: 1348 -----DDRWREERNREHGYDRDFRDRGELRIREYPERGDTWREKRDYVPDRMDWERERLS 1402

Query: 475  DIFGVEETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKA-- 532
            D +   +      + E  +          G   S+   Q      +  Q Q E I KA  
Sbjct: 1403 DRWYPSDVDRHSPMAEH-MPSSHHSSEMMGSDASLDSDQGLGGVMVLSQRQHEIILKAAQ 1461

Query: 533  --KGLVPEDDTKEKIGP--SKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRT 588
              K L  + +  +K+    S+P      PP  S   N  S         RP   PPP   
Sbjct: 1462 ELKMLREQKEQLQKMKDFGSEPQMADHLPPQESRLQNTSS---------RPGMYPPPGS- 1511

Query: 589  TVVSAVPVMPRPPMASVVRLPPGSVIAPM-PPIIHAPRIN--VVPMPPSAPPIMAPRPPP 645
                     P PPM      PPGS++ P  PP   +  +    VP+PP  PP   P PPP
Sbjct: 1512 -------YRPPPPMGK----PPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLPPPPP 1560

Query: 646  MIVP----------------------------------TAFVPAPPVAP-------VPAP 664
            +I P                                  TA +P+ PV P       +P P
Sbjct: 1561 VIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPP 1620

Query: 665  AP----MPPVHPPPPME 677
             P    MPP+  PPP++
Sbjct: 1621 GPVPMGMPPMSKPPPVQ 1637



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 38/143 (26%), Positives = 52/143 (36%), Gaps = 25/143 (17%)

Query: 549 KPNEIPQQPPPPSSATNIPSSAPPITS-------VPRPPTMPPPVRTTVVSAVPVMPRPP 601
           +P+ +P  P PP          PP+          P PP MPPP    +        +  
Sbjct: 77  QPHHLPPPPLPP----------PPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQ 126

Query: 602 MASVVRL-PPGSVIAPMPPIIHAPRINVVPMPPSA--PPIMAPRPPPMIVPTAFVPAPPV 658
           M    R  PPG V   +     +P     P+PP +  PP  +  PPP   P+ + P    
Sbjct: 127 MLHHQRDGPPGLVPMELESPPESP-----PVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQ 181

Query: 659 APVPAPAPMPPVHPPPPMEDEPT 681
             +P   P P   PP      PT
Sbjct: 182 PYLPPAQPSPSQSPPSQSYLAPT 204



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 44/183 (24%), Positives = 60/183 (32%), Gaps = 42/183 (22%)

Query: 522 LQEQIEAIHKAKGLVPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPT 581
           L  Q +  +K + L  + D    + P +    P+ PP P      P S  P +    PP 
Sbjct: 115 LSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVP------PGSYMPPSQSYMPPP 168

Query: 582 MPPPVRTTVVSAVPVMPRPPMASVVRLPPG-SVIAPMPPII------------------- 621
            PPP      S+ P +P P   S  + PP  S +AP P                      
Sbjct: 169 QPPPSYYPPTSSQPYLP-PAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPS 227

Query: 622 -----------HAPRINVVPMPPSAPP----IMAPRPPPMIVPTAFVPAPPVAPVPAPAP 666
                      H+    + P PPSAPP     +   P               AP P P+ 
Sbjct: 228 SQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPST 287

Query: 667 MPP 669
           M P
Sbjct: 288 MTP 290



 Score = 33.9 bits (76), Expect = 0.61
 Identities = 46/179 (25%), Positives = 62/179 (34%), Gaps = 42/179 (23%)

Query: 544 KIGPSKPNEIPQQPPPPSSATNIPSSAP-PITSVPRPPTMPPPV--------RTTVVSAV 594
           + G S     P  PPPP  A  +P ++P P  S    P  P               +  +
Sbjct: 7   RYGGSSHYPPPPVPPPPPVA--LPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQL 64

Query: 595 PVMPRPPMASVVR---LPPGSVIAPMPPIIHAPRI-NVVPMPPSAPPIMAPR-------- 642
             M +  M  V++   LPP  +  P PP++      +  P PP  PP   P         
Sbjct: 65  QQMHQKQMQCVLQPHHLPPPPL--PPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQ 122

Query: 643 -----------PPPMIVPTAFVPAPPVAPVPAPAPMPPVH------PPPPMEDEPTSKK 684
                       PP +VP      P   PVP  + MPP         PPP    PTS +
Sbjct: 123 YKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQ 181



 Score = 32.7 bits (73), Expect = 1.4
 Identities = 45/213 (21%), Positives = 81/213 (38%), Gaps = 26/213 (12%)

Query: 237  REVLDQVCYRVEWAKFQERERKKEEEEKEKERVAYAQIDWHDFVVVETVDFQPNEQ--GN 294
            RE  D V  R++W           E E+  +R   + +D H  +         + +  G+
Sbjct: 1384 REKRDYVPDRMDW-----------ERERLSDRWYPSDVDRHSPMAEHMPSSHHSSEMMGS 1432

Query: 295  FPPPTTPEELGARILIQERYEKF--GESEEVEMEVESDEEDDKQEKAEEPPSQLD----Q 348
                 + + LG  +++ +R  +     ++E++M  E  E+  K +     P   D    Q
Sbjct: 1433 DASLDSDQGLGGVMVLSQRQHEIILKAAQELKMLREQKEQLQKMKDFGSEPQMADHLPPQ 1492

Query: 349  DTQVQDMDE--GSDDEEEGQKVPPP----PETPMPPPLPPTPDQVIVRKDYDPKASKPLP 402
            ++++Q+     G        + PPP    P + + P  PP    V V +   P    P P
Sbjct: 1493 ESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPP 1552

Query: 403  PAPAPDEYLVSPITGEKIPASKMQEHMRIGLLD 435
            P   P   ++ P T   +   +  E    GL D
Sbjct: 1553 PPLPPPPPVIKPQT-SAVEQERWDEDSFYGLWD 1584



 Score = 30.8 bits (68), Expect = 5.1
 Identities = 54/254 (21%), Positives = 75/254 (29%), Gaps = 19/254 (7%)

Query: 342 PPSQLDQDTQVQDMDEGSDDEEEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPL 401
           P   L    Q Q   +    + +G     P E   PP  PP P    +     P  S   
Sbjct: 111 PGPALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYM----PPSQSYMP 166

Query: 402 PPAPAPDEY---LVSPITGEKIPASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAP 458
           PP P P  Y      P      P+       +  L           S +   S  + Y P
Sbjct: 167 PPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLP 226

Query: 459 GLDIESSLKQLAERRTDIFGVEETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAA-- 516
                 S       ++ +      +          Q+P E     G        QQAA  
Sbjct: 227 SSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLE----SGAKNKSTEQQQAAPE 282

Query: 517 --QANITLQEQIEAIHKAKGLVPEDDTKEKIGPSK--PNEIPQQPPPPSSATNIP--SSA 570
              + +T QEQ +  ++   L  +  TK  +   K  P      P P      +P  S  
Sbjct: 283 PDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQV 342

Query: 571 PPITSVPRPPTMPP 584
           P   S   PP  PP
Sbjct: 343 PESPSSEEPPLPPP 356



 Score = 30.8 bits (68), Expect = 5.1
 Identities = 18/45 (40%), Positives = 24/45 (53%), Gaps = 3/45 (6%)

Query: 548  SKPNEIPQQP--PPPSSATNIPSSAPPITSVPRPPTMPPPVRTTV 590
            S+   IP  P  PPP   ++IP   P    +P P + PPPV+ TV
Sbjct: 1597 SETAAIPSAPVLPPPPVHSSIPPPGPVPMGMP-PMSKPPPVQQTV 1640


>gi|23111062 splicing factor, arginine/serine-rich 8 [Homo sapiens]
          Length = 951

 Score = 75.5 bits (184), Expect = 2e-13
 Identities = 46/117 (39%), Positives = 60/117 (51%), Gaps = 9/117 (7%)

Query: 6   VQAVPPPPPVPTEPKQPTEEEASSKEDSAPSK-----PVVGIIYPPPEVRNIVDKTASFV 60
           V    PPPP  T    PT  E SS   S  +      PV  II PPP+V+ ++DK A +V
Sbjct: 408 VTTTAPPPPGTTPLPPPTTAETSSGATSTTTTTSALAPVAAIIPPPPDVQPVIDKLAEYV 467

Query: 61  ARNGPEFEARIRQNEINNPKFNFLNPNDPYHAYYRHKVSEF--KEGKAQEPSAAIPK 115
           ARNG +FE  +R    N+ +F FL P   Y+AYY  K   F  KEG     + + P+
Sbjct: 468 ARNGLKFETSVRAK--NDQRFEFLQPWHQYNAYYEFKKQFFLQKEGGDSMQAVSAPE 522



 Score = 53.5 bits (127), Expect = 7e-07
 Identities = 33/106 (31%), Positives = 53/106 (50%), Gaps = 18/106 (16%)

Query: 18  EPKQPTEEEASSK-----------EDSAPSKPVVGIIYP-----PP--EVRNIVDKTASF 59
           +P +PTEEE  SK           E+  P    +G+  P     PP  ++  I+++TASF
Sbjct: 159 DPSEPTEEEEPSKQREKNEAENLEENEEPFVAPLGLSVPSDVELPPTAKMHAIIERTASF 218

Query: 60  VARNGPEFEARIRQNEINNPKFNFLNPNDPYHAYYRHKVSEFKEGK 105
           V R G +FE  ++  +  N +F+FL  +   + YY+      KEG+
Sbjct: 219 VCRQGAQFEIMLKAKQARNSQFDFLRFDHYLNPYYKFIQKAMKEGR 264



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 108/497 (21%), Positives = 178/497 (35%), Gaps = 56/497 (11%)

Query: 114 PKVMQQQQQTTQQQLPQKVQAQVIQETIVPKEPPPEFEFIAD---PPSISAFDLDVVKLT 170
           P    ++++ ++Q+  +K +A+ ++E   P   P      +D   PP+       +++ T
Sbjct: 160 PSEPTEEEEPSKQR--EKNEAENLEENEEPFVAPLGLSVPSDVELPPTAKMHA--IIERT 215

Query: 171 AQFVARNGRQFLTQLMQKEQRNYQFDFLRPQHSLFNYFTKLVE------QYTKILIPPKG 224
           A FV R G QF   L  K+ RN QFDFLR  H L  Y+ K ++      +YT +      
Sbjct: 216 ASFVCRQGAQFEIMLKAKQARNSQFDFLRFDHYLNPYY-KFIQKAMKEGRYTVLAENKSD 274

Query: 225 LFSKLKKEAENPREVLDQVCYRVEWAKFQERERKKEEEEKEKERVAYAQIDWHDFVVVET 284
              K    ++N  +  ++    +  + F  ++  + EE  +  +V       H    +  
Sbjct: 275 EKKKSGVSSDNEDDDDEEDGNYLHPSLFASKKCNRLEELMKPLKVVDPD---HPLAALVR 331

Query: 285 VDFQPNEQGNFPPPTTPEELGARILIQERYEKFGESEEVEMEVESDEEDDKQEKAEEPPS 344
                  Q +   PT     GA +    + E   +S    M        D       PP 
Sbjct: 332 -----KAQADSSTPTPHNADGAPVQ-PSQVEYTADSTVAAMYYSYYMLPDGTYCLAPPPP 385

Query: 345 QLDQDTQVQDMDEG---SDDEEEGQKVPPPP-ETPMPPPLPPTPDQVIVRKDYDPKASKP 400
            +D  T    +  G   S+        PPPP  TP+PPP                 A  P
Sbjct: 386 GIDVTTYYSTLPAGVTVSNSPGVTTTAPPPPGTTPLPPPTTAETSSGATSTTTTTSALAP 445

Query: 401 ----LPPAPAPD-------EYLVSPITGEKIPAS-KMQEHMRIGLLDP-----RWLEQRD 443
               +PP P          EY+     G K   S + +   R   L P      + E + 
Sbjct: 446 VAAIIPPPPDVQPVIDKLAEYVAR--NGLKFETSVRAKNDQRFEFLQPWHQYNAYYEFKK 503

Query: 444 RSIREKQSDDEVYAPGLDIESSLKQLAERRTDI--FGVEETA--IGKKIGEEEIQKPEEK 499
           +   +K+  D + A     E+      E+ +D    G  E A  +G + G     K E  
Sbjct: 504 QFFLQKEGGDSMQAVSAPEEAPTDSAPEKPSDAGEDGAPEDAAEVGARAGSG--GKKEAS 561

Query: 500 VTWDGHSGSMARTQQAAQANITLQEQIEAIHKAKGLVPEDDTKEKIGPSKPNEIPQQPPP 559
            +     G + +   A  +     ++ + +   K  V  DD  +    SK      Q   
Sbjct: 562 SSKTVPDGKLVKASFAPISFAIKAKENDLLPLEKNRVKLDDDSDDDEESKEG----QESS 617

Query: 560 PSSATNIPSSAPPITSV 576
            S+A   P+ APP   V
Sbjct: 618 SSAANTNPAVAPPCVVV 634



 Score = 39.3 bits (90), Expect = 0.014
 Identities = 43/165 (26%), Positives = 58/165 (35%), Gaps = 34/165 (20%)

Query: 568 SSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSV-IAPMPP------- 619
           SS P   +    P  P  V  T  S V  M      S   LP G+  +AP PP       
Sbjct: 337 SSTPTPHNADGAPVQPSQVEYTADSTVAAM----YYSYYMLPDGTYCLAPPPPGIDVTTY 392

Query: 620 ---------IIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPV 670
                    + ++P +     PP   P   P PPP    T+           A AP+  +
Sbjct: 393 YSTLPAGVTVSNSPGVTTTAPPP---PGTTPLPPPTTAETSSGATSTTTTTSALAPVAAI 449

Query: 671 HPPPPMEDEPTSKKLKTEDSLMPEEEFLRRNKGPVSIKVQVPNMQ 715
            PPPP + +P   KL          E++ RN       V+  N Q
Sbjct: 450 IPPPP-DVQPVIDKL---------AEYVARNGLKFETSVRAKNDQ 484


>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sapiens]
          Length = 2462

 Score = 75.1 bits (183), Expect = 2e-13
 Identities = 155/697 (22%), Positives = 244/697 (35%), Gaps = 116/697 (16%)

Query: 87   NDPYHAYYRHKVSEFKEGKAQEPSAAIPKVMQQQQQTTQQQLPQKVQAQVIQETIVPKEP 146
            N+ Y +  R   S  + GK+Q+         QQQQQ  QQQ  Q+   +  QE    KE 
Sbjct: 476  NENYKSLVRR--SYRRRGKSQQ--------QQQQQQQQQQQQQQQPMPRSSQEEKDEKEK 525

Query: 147  PPEFEFIADPPSISAFDLDVVKLTA-----------QFVARNGRQF----------LTQL 185
              E E   + P +     D++K              + VA  GR+           +T+ 
Sbjct: 526  EKEAEKEEEKPEVENDKEDLLKEKTDDTSGEDNDEKEAVASKGRKTANSQGRRKGRITRS 585

Query: 186  MQKEQRNYQFDFLRPQHSL------FNYFTKLVEQYTKILIPPKGLFSKLKKEAENPREV 239
            M  E  + +   + PQ S        N  ++  E+  ++    KGL    +  +   R V
Sbjct: 586  MANEANSEEA--ITPQQSAELASMELNESSRWTEE--EMETAKKGLLEHGRNWSAIARMV 641

Query: 240  LDQVCYRVEWAKFQERERKKEEE-------EKEKERVAYAQIDWHDFVVVETVDFQPNEQ 292
              +   + +   F  ++R+  +E       + EKER A  +         +      +E+
Sbjct: 642  GSKTVSQCKNFYFNYKKRQNLDEILQQHKLKMEKERNARRK--------KKKAPAAASEE 693

Query: 293  GNFPPPTTPEELGARILIQERYEKFGESEEVEMEVESDEEDDKQEKAEEPPSQLDQDTQV 352
              FPP                     E EE+E    S  E++  E+AE   +    DT+ 
Sbjct: 694  AAFPPVV-------------------EDEEMEASGVSGNEEEMVEEAEATVNN-SSDTES 733

Query: 353  QDMDEGSDDEEEGQKVPPPPET---PMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDE 409
                     ++ GQ  P PP T     PPP PPTP    +    +P  +     AP P  
Sbjct: 734  IPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPP 793

Query: 410  YLVSPITGEKIPASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQL 469
               SP     +   + +E            E++     E+ + D   A    ++S   + 
Sbjct: 794  APPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAVDTGKAEE-PVKSECTEE 852

Query: 470  AE----RRTDIFGVEETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQ 525
            AE    +  D    E TA G  +  E+ +    + T    SG+   +  +A  +    ++
Sbjct: 853  AEEGPAKGKDAEAAEATAEG-ALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDE 911

Query: 526  IEAIHKAKGLVPEDDTKEKIGPSKPNEIPQQP------------PPPSSATNI--PSSAP 571
             E   K + L P        G  + N  PQ+P             PP   T +  P    
Sbjct: 912  AEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRAAAIPPIQVTKVHEPPRED 971

Query: 572  PITSVPRPPTMPPPVRTTVVSAVPVMP--RPPMASVVRLPPGSVIAPMPPIIHAPRINVV 629
               + P PP  PPP      S  P  P   P   S    PP    A  P    A      
Sbjct: 972  AAPTKPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQ 1031

Query: 630  PMPPSAP----PIMAPRPPPMIV--------PTAFVPAPPVAPVPAPA--PMPPVHPPPP 675
             +P   P     +  P PP  ++        P+AF  APP  P+P        PV P PP
Sbjct: 1032 KLPGDPPCWTSGLPFPVPPREVIKASPHAPDPSAFSYAPPGHPLPLGLHDTARPVLPRPP 1091

Query: 676  MEDEPTSKKLKTEDSLMPEEEFLRRNKGPVSIKVQVP 712
                P       +   + E +    ++G +S+++ VP
Sbjct: 1092 TISNPPPLISSAKHPSVLERQIGAISQG-MSVQLHVP 1127



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 94/473 (19%), Positives = 183/473 (38%), Gaps = 91/473 (19%)

Query: 179 RQFLTQLMQKEQRNYQFDFLRPQHSLFNYFTKLVEQYTKILIPPKGLFSKLKKEAENPRE 238
           RQ +    ++E+  ++  F++   + F      +E+ T   +    L+  L K+ EN + 
Sbjct: 426 RQVMNMWSEQEKETFREKFMQHPKN-FGLIASFLERKT---VAECVLYYYLTKKNENYKS 481

Query: 239 VLDQVCYRVEWAKFQERERKKEEEEKEKERVAYAQIDWHDFVVVETVDFQPNEQGNFPPP 298
           ++ +         ++ R + ++++++++++                   Q  +Q    P 
Sbjct: 482 LVRR--------SYRRRGKSQQQQQQQQQQ-------------------QQQQQQQPMPR 514

Query: 299 TTPEELGARILIQERYEKFGESEEVEMEVESDEEDDKQEKAEEPPSQLDQDTQVQDMDEG 358
           ++ EE       ++  EK  E EE + EVE+D+ED  +EK +        DT  +D DE 
Sbjct: 515 SSQEEKD-----EKEKEKEAEKEEEKPEVENDKEDLLKEKTD--------DTSGEDNDEK 561

Query: 359 SDDEEEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGE 418
                +G+K                 ++    +   P+ S  L      +    S  T E
Sbjct: 562 EAVASKGRKTANSQGRRKGRITRSMANEANSEEAITPQQSAELASMELNES---SRWTEE 618

Query: 419 KIPASK--MQEHMRIGLLDPRWLEQRDRS--------IREKQSDDEV---YAPGLDIESS 465
           ++  +K  + EH R      R +  +  S         +++Q+ DE+   +   ++ E +
Sbjct: 619 EMETAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQNLDEILQQHKLKMEKERN 678

Query: 466 LKQLAERRTDIFGVEETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQ 525
            ++  +++      EE A    + +EE++         G SG+     + A+A +     
Sbjct: 679 ARR-KKKKAPAAASEEAAFPPVVEDEEMEA-------SGVSGNEEEMVEEAEATVNNSSD 730

Query: 526 IEAIHKAKGLVPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPP 585
            E+I       P  +  +  G + P       PP +   + P   PP    P P  +P P
Sbjct: 731 TESIPS-----PHTEAAKDTGQNGPK------PPATLGADGPPPGPP---TPPPEDIPAP 776

Query: 586 VRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPI 638
              T  S     P PP A      P S  AP PP++  P+        +APP+
Sbjct: 777 TEPTPASEATGAPTPPPA------PPSPSAP-PPVV--PKEEKEEETAAAPPV 820



 Score = 37.4 bits (85), Expect = 0.055
 Identities = 78/354 (22%), Positives = 122/354 (34%), Gaps = 83/354 (23%)

Query: 372  PETP-MPPPLPPTPDQVIVRKDYDPKASKPL-------PPAPAPDEYLVSPITGEKIPAS 423
            P  P + PP P TP   + R  Y P A +P        P +P    +L  P T     +S
Sbjct: 1729 PHLPVLVPPTPGTPATAMDRLAYLPTAPQPFSSRHSSSPLSPGGPTHLTKPTT----TSS 1784

Query: 424  KMQEHMRIGLLDPRWLEQRDRSIREKQSDDE---VYAPGLDIESSLKQLAERRTDIFGVE 480
              +E  R    D     +R++SI    +  E   ++ PG +  S             G  
Sbjct: 1785 SERERDRDRERDRD--REREKSILTSTTTVEHAPIWRPGTEQSS-------------GSS 1829

Query: 481  ETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKA--KGLVPE 538
             ++ G   G     +P        HS    RTQ A      LQ++   +H    KG++  
Sbjct: 1830 GSSGG---GGGSSSRPASHSHAHQHSPISPRTQDA------LQQRPSVLHNTGMKGIITA 1880

Query: 539  DDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVM- 597
                             +P  P+   +  +S+P   +   PP    P+  T+    P + 
Sbjct: 1881 ----------------VEPSTPTVLRSTSTSSPVRPAATFPPATHCPLGGTLDGVYPTLM 1924

Query: 598  ---------PRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIV 648
                     PR       R   G      PP           + P++ P     P P++ 
Sbjct: 1925 EPVLLPKEAPRVARPERPRADTGHAFLAKPPARSG-------LEPASSPSKGSEPRPLVP 1977

Query: 649  PT------AFVPAPPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMPEEE 696
            P       A  PA  +AP  A +P PP   PP    +P  +K +++   + E E
Sbjct: 1978 PVSGHATIARTPAKNLAPHHA-SPDPPA--PPASASDPHREKTQSKPFSIQELE 2028



 Score = 30.4 bits (67), Expect = 6.7
 Identities = 19/81 (23%), Positives = 35/81 (43%), Gaps = 2/81 (2%)

Query: 319 ESEEVEMEVESDEEDDKQEKAEEPPSQLDQDTQVQDMDEGSDDEEEGQKVPPPPETPMPP 378
           E E V   +  +E     ++ +   + ++Q  Q+  + +     EE    PP PE P+ P
Sbjct: 159 ELELVPPRLSKEELIQNMDRVDREITMVEQ--QISKLKKKQQQLEEEAAKPPEPEKPVSP 216

Query: 379 PLPPTPDQVIVRKDYDPKASK 399
           P   +  + +V+  YD    K
Sbjct: 217 PPIESKHRSLVQIIYDENRKK 237



 Score = 30.0 bits (66), Expect = 8.8
 Identities = 17/48 (35%), Positives = 19/48 (39%), Gaps = 4/48 (8%)

Query: 2   PAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPPEV 49
           P GP    P   P PTEP   +E   +     AP  P      PPP V
Sbjct: 762 PPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSA----PPPVV 805


>gi|160707881 formin 2 [Homo sapiens]
          Length = 1722

 Score = 75.1 bits (183), Expect = 2e-13
 Identities = 49/129 (37%), Positives = 62/129 (48%), Gaps = 16/129 (12%)

Query: 557  PPPPSSATNIPSSAP-PITSVPRPPTMP----PPVRTTVVSAVPVMPRPPMASVVRLP-- 609
            PPPP     IP   P P   +P PP +P    PP      + +P  P  P A +   P  
Sbjct: 1076 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1135

Query: 610  PGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAP---VPAPAP 666
            PG+ I P PP+   PR+  +P PP  P    P PPP+  P A +P PP  P   +P P P
Sbjct: 1136 PGAGIPPPPPL---PRVG-IPPPPPLPGAGIPPPPPL--PGAGIPPPPPLPGVGIPPPPP 1189

Query: 667  MPPVHPPPP 675
            +P V  PPP
Sbjct: 1190 LPGVGIPPP 1198



 Score = 74.3 bits (181), Expect = 4e-13
 Identities = 47/139 (33%), Positives = 65/139 (46%), Gaps = 22/139 (15%)

Query: 547  PSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P+ P+    QPPP      +P   PP+     PP  PPP     +    ++P PP+    
Sbjct: 889  PTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPP--PPP-----LPGAGILPLPPLPGAG 941

Query: 607  RLP----PGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAP-- 660
              P    PG+ I P PP+  A     +P+PP  P    P PPP+  P A +P PP  P  
Sbjct: 942  IPPPPPLPGAAIPPPPPLPGAG----IPLPPPLPGAGIPPPPPL--PGAGIPPPPPLPGA 995

Query: 661  -VPAPAPMP--PVHPPPPM 676
             +P P P+P   + PPPP+
Sbjct: 996  GIPPPPPLPGAGIPPPPPL 1014



 Score = 73.2 bits (178), Expect = 9e-13
 Identities = 48/132 (36%), Positives = 63/132 (47%), Gaps = 18/132 (13%)

Query: 557  PPPPSSATNIPSSAP-PITSVPRPPTMP----PPVRTTVVSAVPVMPRPPMASVVRLP-- 609
            PPPP     IP   P P   +P PP +P    PP      + +P  P  P A +   P  
Sbjct: 1021 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1080

Query: 610  PGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAP---VPAPAP 666
            PG+ I P PP+  A     +P PP  P +  P PPP+  P A +P PP  P   +P P P
Sbjct: 1081 PGAGIPPPPPLPGAG----IPPPPPLPGVGIPPPPPL--PGAGIPPPPPLPGAGIPPPPP 1134

Query: 667  MP--PVHPPPPM 676
            +P   + PPPP+
Sbjct: 1135 LPGAGIPPPPPL 1146



 Score = 72.8 bits (177), Expect = 1e-12
 Identities = 45/130 (34%), Positives = 62/130 (47%), Gaps = 17/130 (13%)

Query: 558 PPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLP------PG 611
           PPP   T   SS P +  VP PP   P +    + +  +   PP+     LP      PG
Sbjct: 858 PPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPG 917

Query: 612 SVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAP---VPAPAPMP 668
           + I P PP+   P   ++P+PP  P    P PPP+  P A +P PP  P   +P P P+P
Sbjct: 918 AGIPPPPPL---PGAGILPLPP-LPGAGIPPPPPL--PGAAIPPPPPLPGAGIPLPPPLP 971

Query: 669 --PVHPPPPM 676
              + PPPP+
Sbjct: 972 GAGIPPPPPL 981



 Score = 72.8 bits (177), Expect = 1e-12
 Identities = 48/129 (37%), Positives = 60/129 (46%), Gaps = 16/129 (12%)

Query: 557  PPPPSSATNIPSSAP-PITSVPRPPTMP----PPVRTTVVSAVPVMPRPPMASVVRLP-- 609
            PPPP     IP   P P   +P PP +P    PP        +P  P  P A +   P  
Sbjct: 1065 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPL 1124

Query: 610  PGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAP---VPAPAP 666
            PG+ I P PP+  A     +P PP  P +  P PPP+  P A +P PP  P   +P P P
Sbjct: 1125 PGAGIPPPPPLPGAG----IPPPPPLPRVGIPPPPPL--PGAGIPPPPPLPGAGIPPPPP 1178

Query: 667  MPPVHPPPP 675
            +P V  PPP
Sbjct: 1179 LPGVGIPPP 1187



 Score = 72.4 bits (176), Expect = 2e-12
 Identities = 48/129 (37%), Positives = 61/129 (47%), Gaps = 16/129 (12%)

Query: 557  PPPPSSATNIPSSAP-PITSVPRPPTMP----PPVRTTVVSAVPVMPRPPMASVVRLP-- 609
            PPPP     IP   P P   +P PP +P    PP      + +P  P  P A +   P  
Sbjct: 1032 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1091

Query: 610  PGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAP---VPAPAP 666
            PG+ I P PP+   P +  +P PP  P    P PPP+  P A +P PP  P   +P P P
Sbjct: 1092 PGAGIPPPPPL---PGVG-IPPPPPLPGAGIPPPPPL--PGAGIPPPPPLPGAGIPPPPP 1145

Query: 667  MPPVHPPPP 675
            +P V  PPP
Sbjct: 1146 LPRVGIPPP 1154



 Score = 70.9 bits (172), Expect = 4e-12
 Identities = 48/153 (31%), Positives = 69/153 (45%), Gaps = 39/153 (25%)

Query: 557  PPPPSSATNIPSSAPPITSVPRPPTM------PPPVRTTVVSAVPVMPRPPMASVVRLPP 610
            PPPP     +P+   P T++P+PP +      PPP      + +P  P  P A ++ LPP
Sbjct: 879  PPPPLPGMTVPTL--PSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPP 936

Query: 611  -------------GSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMI---------V 648
                         G+ I P PP+  A     +P+PP  P    P PPP+          +
Sbjct: 937  LPGAGIPPPPPLPGAAIPPPPPLPGAG----IPLPPPLPGAGIPPPPPLPGAGIPPPPPL 992

Query: 649  PTAFVPAPPVAP---VPAPAPMP--PVHPPPPM 676
            P A +P PP  P   +P P P+P   + PPPP+
Sbjct: 993  PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1025



 Score = 70.9 bits (172), Expect = 4e-12
 Identities = 48/132 (36%), Positives = 62/132 (46%), Gaps = 18/132 (13%)

Query: 557  PPPPSSATNIPSSAP-PITSVPRPPTMP----PPVRTTVVSAVPVMPRPPMASVVRLPP- 610
            PPPP     IP   P P   +P PP +P    PP      + +P  P  P A +   PP 
Sbjct: 944  PPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1003

Query: 611  -GSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAP---VPAPAP 666
             G+ I P PP+  A     +P PP  P    P PPP+  P A +P PP  P   +P P P
Sbjct: 1004 PGAGIPPPPPLPGAG----IPPPPPLPGAGIPPPPPL--PGAGIPPPPPLPGAGIPPPPP 1057

Query: 667  MP--PVHPPPPM 676
            +P   + PPPP+
Sbjct: 1058 LPGAGIPPPPPL 1069



 Score = 70.5 bits (171), Expect = 6e-12
 Identities = 50/153 (32%), Positives = 67/153 (43%), Gaps = 29/153 (18%)

Query: 547  PSKPNEIPQQPPPPSSATNIPSSAP------------PITSVPRPPTMP----PPVRTTV 590
            P +  E+   PPPP     IP   P            P   +P PP +P    PP     
Sbjct: 901  PLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLP 960

Query: 591  VSAVPVMPRPPMASVVRLPP--GSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIV 648
             + +P+ P  P A +   PP  G+ I P PP+  A     +P PP  P    P PPP+  
Sbjct: 961  GAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG----IPPPPPLPGAGIPPPPPL-- 1014

Query: 649  PTAFVPAPPVAP---VPAPAPMP--PVHPPPPM 676
            P A +P PP  P   +P P P+P   + PPPP+
Sbjct: 1015 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1047



 Score = 70.5 bits (171), Expect = 6e-12
 Identities = 48/132 (36%), Positives = 61/132 (46%), Gaps = 18/132 (13%)

Query: 557  PPPPSSATNIPSSAP-PITSVPRPPTMP----PPVRTTVVSAVPVMPRPPMASVVRLP-- 609
            PPPP     IP   P P   +P PP +P    PP      + +P  P  P A +   P  
Sbjct: 1043 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1102

Query: 610  PGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAP---VPAPAP 666
            PG  I P PP+  A     +P PP  P    P PPP+  P A +P PP  P   +P P P
Sbjct: 1103 PGVGIPPPPPLPGAG----IPPPPPLPGAGIPPPPPL--PGAGIPPPPPLPRVGIPPPPP 1156

Query: 667  MP--PVHPPPPM 676
            +P   + PPPP+
Sbjct: 1157 LPGAGIPPPPPL 1168



 Score = 70.1 bits (170), Expect = 8e-12
 Identities = 47/132 (35%), Positives = 61/132 (46%), Gaps = 18/132 (13%)

Query: 557  PPPPSSATNIPSSAP-PITSVPRPPTMP----PPVRTTVVSAVPVMPRPPMASVVRLPP- 610
            PPPP     IP   P P   +P PP +P    PP      + +P  P  P A +   PP 
Sbjct: 1010 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1069

Query: 611  -GSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAP---VPAPAP 666
             G+ I P PP+  A     +P PP  P    P PPP+  P   +P PP  P   +P P P
Sbjct: 1070 PGAGIPPPPPLPGAG----IPPPPPLPGAGIPPPPPL--PGVGIPPPPPLPGAGIPPPPP 1123

Query: 667  MP--PVHPPPPM 676
            +P   + PPPP+
Sbjct: 1124 LPGAGIPPPPPL 1135



 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 48/137 (35%), Positives = 65/137 (47%), Gaps = 17/137 (12%)

Query: 547  PSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P  P  +P    P   +T IP   P   +   PP  PPP+     + +P  P  P A ++
Sbjct: 877  PPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPP-PPPLPG---AGIPPPPPLPGAGIL 932

Query: 607  RLP--PGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAP---V 661
             LP  PG+ I P PP+  A     +P PP  P    P PPP+  P A +P PP  P   +
Sbjct: 933  PLPPLPGAGIPPPPPLPGA----AIPPPPPLPGAGIPLPPPL--PGAGIPPPPPLPGAGI 986

Query: 662  PAPAPMP--PVHPPPPM 676
            P P P+P   + PPPP+
Sbjct: 987  PPPPPLPGAGIPPPPPL 1003



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 53/167 (31%), Positives = 70/167 (41%), Gaps = 21/167 (12%)

Query: 536  VPEDDTKEKIGPSKPNEIPQQ---PPPPSSATNIPSSAP-PITSVPRPPTMP----PPVR 587
            +P       +G   P  +P     PPPP     IP   P P   +P PP +P    PP  
Sbjct: 1096 IPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPP 1155

Query: 588  TTVVSAVPVMPRPPMASVVRLPP--GSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPP 645
                + +P  P  P A +   PP  G  I P PP+   P + + P PP  P    P PPP
Sbjct: 1156 PLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPL---PGVGIPP-PPPLPGAGIPPPPP 1211

Query: 646  MIVPTAFVPAPPVAPVPAPA---PMPPVHP--PPPMEDEPTSKKLKT 687
            +  P   +P  P  P+P P    P PP+ P   PP+  +  S  L T
Sbjct: 1212 L--PGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPT 1256



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 42/161 (26%), Positives = 66/161 (40%), Gaps = 36/161 (22%)

Query: 549 KPNEIPQQPPPP-----SSATNIPSSAPPIT---------------------SVPRPPTM 582
           +P +   QPPPP     S+    P S PP +                     ++P PP +
Sbjct: 802 QPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPL 861

Query: 583 PPPVRTTVVSAVPVMPRPPM---ASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIM 639
           P    ++ +  + ++P PP       V   P + I   PP+       ++P PP   P  
Sbjct: 862 PCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPL---QGTEMLPPPPPPLPGA 918

Query: 640 APRPPPMIVPTAFVPAPPV--APVPAPAPMP--PVHPPPPM 676
              PPP +     +P PP+  A +P P P+P   + PPPP+
Sbjct: 919 GIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPL 959



 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 44/146 (30%), Positives = 60/146 (41%), Gaps = 23/146 (15%)

Query: 536  VPEDDTKEKIGPSKPNEIPQQ---PPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVS 592
            +P      ++G   P  +P     PPPP     IP   PP+  V  PP  PPP+      
Sbjct: 1140 IPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPP-PPLPGVGIPP--PPPL-----P 1191

Query: 593  AVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINV--VPMPPSAPPIMAPRPPPMIVPT 650
             V + P PP+       PG+ I P PP+   P + +   P PP  PP     PPP++  +
Sbjct: 1192 GVGIPPPPPL-------PGAGIPPPPPL---PGMGIPPAPAPPLPPPGTGIPPPPLLPVS 1241

Query: 651  AFVPAPPVAPVPAPAPMPPVHPPPPM 676
                 P V     P P      PPP+
Sbjct: 1242 GPPLLPQVGSSTLPTPQVCGFLPPPL 1267



 Score = 33.9 bits (76), Expect = 0.61
 Identities = 21/62 (33%), Positives = 27/62 (43%), Gaps = 14/62 (22%)

Query: 364 EGQKVPPPPETPMP----PPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEK 419
           +G ++ PPP  P+P    PP PP P   I+          PLPP P        P+ G  
Sbjct: 903 QGTEMLPPPPPPLPGAGIPPPPPLPGAGIL----------PLPPLPGAGIPPPPPLPGAA 952

Query: 420 IP 421
           IP
Sbjct: 953 IP 954



 Score = 32.7 bits (73), Expect = 1.4
 Identities = 23/60 (38%), Positives = 26/60 (43%), Gaps = 3/60 (5%)

Query: 365 GQKVPPPPETPMPP--PLPPTPDQVIVRKDYDPKAS-KPLPPAPAPDEYLVSPITGEKIP 421
           G  +PPPP  P     PLPP P   I      P A+  P PP P     L  P+ G  IP
Sbjct: 917 GAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIP 976



 Score = 32.3 bits (72), Expect = 1.8
 Identities = 17/46 (36%), Positives = 20/46 (43%)

Query: 2    PAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPP 47
            P  P   +PPPPP+P     P      +     P  P VGI  PPP
Sbjct: 1067 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPP 1112



 Score = 32.3 bits (72), Expect = 1.8
 Identities = 17/46 (36%), Positives = 20/46 (43%)

Query: 2    PAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPP 47
            P  P   +PPPPP+P     P      +     P  P VGI  PPP
Sbjct: 1111 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPP 1156



 Score = 32.3 bits (72), Expect = 1.8
 Identities = 25/63 (39%), Positives = 27/63 (42%), Gaps = 11/63 (17%)

Query: 365  GQKVPPPPETP---MPPPLPPTPDQVIVRKDYDPKASKPLPP-------APAPDEYLVSP 414
            G  +PPPP  P   +PPP PP P   I      P A  P PP        PAP   L  P
Sbjct: 1170 GAGIPPPPPLPGVGIPPP-PPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPP 1228

Query: 415  ITG 417
             TG
Sbjct: 1229 GTG 1231



 Score = 32.0 bits (71), Expect = 2.3
 Identities = 24/62 (38%), Positives = 28/62 (45%), Gaps = 7/62 (11%)

Query: 365 GQKVPPPPETP---MPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYL--VSPITGEK 419
           G  +PPPP  P   +PPP PP P   I      P A  P PP P P   +    P+ G  
Sbjct: 939 GAGIPPPPPLPGAAIPPP-PPLPGAGIPLPPPLPGAGIP-PPPPLPGAGIPPPPPLPGAG 996

Query: 420 IP 421
           IP
Sbjct: 997 IP 998



 Score = 32.0 bits (71), Expect = 2.3
 Identities = 24/62 (38%), Positives = 28/62 (45%), Gaps = 7/62 (11%)

Query: 365  GQKVPPPPETP---MPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYL--VSPITGEK 419
            G  +PPPP  P   +PPP PP P   I      P A  P PP P P   +    P+ G  
Sbjct: 983  GAGIPPPPPLPGAGIPPP-PPLPGAGIPPPPPLPGAGIP-PPPPLPGAGIPPPPPLPGAG 1040

Query: 420  IP 421
            IP
Sbjct: 1041 IP 1042



 Score = 32.0 bits (71), Expect = 2.3
 Identities = 24/62 (38%), Positives = 28/62 (45%), Gaps = 7/62 (11%)

Query: 365  GQKVPPPPETP---MPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYL--VSPITGEK 419
            G  +PPPP  P   +PPP PP P   I      P A  P PP P P   +    P+ G  
Sbjct: 1005 GAGIPPPPPLPGAGIPPP-PPLPGAGIPPPPPLPGAGIP-PPPPLPGAGIPPPPPLPGAG 1062

Query: 420  IP 421
            IP
Sbjct: 1063 IP 1064



 Score = 32.0 bits (71), Expect = 2.3
 Identities = 24/62 (38%), Positives = 28/62 (45%), Gaps = 7/62 (11%)

Query: 365  GQKVPPPPETP---MPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYL--VSPITGEK 419
            G  +PPPP  P   +PPP PP P   I      P A  P PP P P   +    P+ G  
Sbjct: 1027 GAGIPPPPPLPGAGIPPP-PPLPGAGIPPPPPLPGAGIP-PPPPLPGAGIPPPPPLPGAG 1084

Query: 420  IP 421
            IP
Sbjct: 1085 IP 1086



 Score = 32.0 bits (71), Expect = 2.3
 Identities = 17/46 (36%), Positives = 20/46 (43%)

Query: 2    PAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPP 47
            P  P   +PPPPP+P     P      +     P  P VGI  PPP
Sbjct: 1144 PPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPP 1189



 Score = 31.6 bits (70), Expect = 3.0
 Identities = 16/47 (34%), Positives = 20/47 (42%)

Query: 1   MPAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPP 47
           +P  P   +PPPPP+P     P      +     P  P  GI  PPP
Sbjct: 934 LPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPP 980



 Score = 31.6 bits (70), Expect = 3.0
 Identities = 24/62 (38%), Positives = 28/62 (45%), Gaps = 7/62 (11%)

Query: 365  GQKVPPPPETP---MPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYL--VSPITGEK 419
            G  +PPPP  P   +PPP PP P   I      P A  P PP P P   +    P+ G  
Sbjct: 1049 GAGIPPPPPLPGAGIPPP-PPLPGAGIPPPPPLPGAGIP-PPPPLPGAGIPPPPPLPGVG 1106

Query: 420  IP 421
            IP
Sbjct: 1107 IP 1108



 Score = 31.6 bits (70), Expect = 3.0
 Identities = 24/62 (38%), Positives = 28/62 (45%), Gaps = 7/62 (11%)

Query: 365  GQKVPPPPETP---MPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYL--VSPITGEK 419
            G  +PPPP  P   +PPP PP P   I      P A  P PP P P   +    P+ G  
Sbjct: 1082 GAGIPPPPPLPGAGIPPP-PPLPGVGIPPPPPLPGAGIP-PPPPLPGAGIPPPPPLPGAG 1139

Query: 420  IP 421
            IP
Sbjct: 1140 IP 1141



 Score = 31.2 bits (69), Expect = 3.9
 Identities = 22/56 (39%), Positives = 26/56 (46%), Gaps = 4/56 (7%)

Query: 368 VPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYL--VSPITGEKIP 421
           +PP P   +PPP PP P   I      P A  PLPP P P   +    P+ G  IP
Sbjct: 934 LPPLPGAGIPPP-PPLPGAAIPPPPPLPGAGIPLPP-PLPGAGIPPPPPLPGAGIP 987



 Score = 31.2 bits (69), Expect = 3.9
 Identities = 24/62 (38%), Positives = 28/62 (45%), Gaps = 7/62 (11%)

Query: 365  GQKVPPPPETP---MPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYL--VSPITGEK 419
            G  +PPPP  P   +PPP PP P   I      P A  P PP P P   +    P+ G  
Sbjct: 1137 GAGIPPPPPLPRVGIPPP-PPLPGAGIPPPPPLPGAGIP-PPPPLPGVGIPPPPPLPGVG 1194

Query: 420  IP 421
            IP
Sbjct: 1195 IP 1196



 Score = 31.2 bits (69), Expect = 3.9
 Identities = 17/46 (36%), Positives = 19/46 (41%)

Query: 2    PAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPP 47
            P  P   +PPPPP+P     P            P  P VGI  PPP
Sbjct: 1155 PPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPP 1200



 Score = 31.2 bits (69), Expect = 3.9
 Identities = 16/54 (29%), Positives = 23/54 (42%), Gaps = 3/54 (5%)

Query: 365  GQKVPPPPETPMPPP---LPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPI 415
            G  +PP P  P+PPP   +PP P   +      P+      P P    +L  P+
Sbjct: 1214 GMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPL 1267



 Score = 30.8 bits (68), Expect = 5.1
 Identities = 25/72 (34%), Positives = 29/72 (40%), Gaps = 16/72 (22%)

Query: 365  GQKVPPPPETP-----MPPPLP--------PTPDQVIVRKDYDPKASKPLPPAPAPDEYL 411
            G  +PPPP  P     +PPPLP        P P   I      P A  P PP P P   +
Sbjct: 950  GAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP-PPPPLPGAGI 1008

Query: 412  --VSPITGEKIP 421
                P+ G  IP
Sbjct: 1009 PPPPPLPGAGIP 1020



 Score = 30.8 bits (68), Expect = 5.1
 Identities = 16/46 (34%), Positives = 19/46 (41%)

Query: 2    PAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPP 47
            P  P   +PPPPP+P     P      +     P  P  GI  PPP
Sbjct: 968  PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1013



 Score = 30.8 bits (68), Expect = 5.1
 Identities = 16/46 (34%), Positives = 19/46 (41%)

Query: 2    PAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPP 47
            P  P   +PPPPP+P     P      +     P  P  GI  PPP
Sbjct: 1001 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1046



 Score = 30.8 bits (68), Expect = 5.1
 Identities = 16/46 (34%), Positives = 19/46 (41%)

Query: 2    PAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPP 47
            P  P   +PPPPP+P     P      +     P  P  GI  PPP
Sbjct: 1034 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1079



 Score = 30.8 bits (68), Expect = 5.1
 Identities = 24/62 (38%), Positives = 28/62 (45%), Gaps = 7/62 (11%)

Query: 365  GQKVPPPPETP---MPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYL--VSPITGEK 419
            G  +PPPP  P   +PPP PP P   I      P A  P PP P P   +    P+ G  
Sbjct: 1104 GVGIPPPPPLPGAGIPPP-PPLPGAGIPPPPPLPGAGIP-PPPPLPRVGIPPPPPLPGAG 1161

Query: 420  IP 421
            IP
Sbjct: 1162 IP 1163



 Score = 30.4 bits (67), Expect = 6.7
 Identities = 15/33 (45%), Positives = 19/33 (57%)

Query: 115 KVMQQQQQTTQQQLPQKVQAQVIQETIVPKEPP 147
           ++ QQQQQ  Q QL Q+ Q Q +Q    P  PP
Sbjct: 204 RLQQQQQQQLQLQLQQQQQQQQLQGAEEPAAPP 236



 Score = 30.4 bits (67), Expect = 6.7
 Identities = 24/101 (23%), Positives = 34/101 (33%), Gaps = 19/101 (18%)

Query: 337 EKAEEPPSQLDQDTQVQDMDEGSDDEEEGQKVPPPPETP-------------MPPPLPPT 383
           +   +PP  +  + Q       S   +    +P PP  P             +PPP PP 
Sbjct: 824 QPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPL 883

Query: 384 PDQVIVRKDYDPKASKPLPPAPAPDEYL---VSPITGEKIP 421
           P   +      P  + P PP     E L     P+ G  IP
Sbjct: 884 PGMTVPTL---PSTAIPQPPPLQGTEMLPPPPPPLPGAGIP 921



 Score = 30.4 bits (67), Expect = 6.7
 Identities = 23/62 (37%), Positives = 27/62 (43%), Gaps = 7/62 (11%)

Query: 365  GQKVPPPPETP---MPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYL--VSPITGEK 419
            G  +PPPP  P   +PPP PP P   I      P    P PP P P   +    P+ G  
Sbjct: 1071 GAGIPPPPPLPGAGIPPP-PPLPGAGIPPPPPLPGVGIP-PPPPLPGAGIPPPPPLPGAG 1128

Query: 420  IP 421
            IP
Sbjct: 1129 IP 1130



 Score = 30.4 bits (67), Expect = 6.7
 Identities = 16/46 (34%), Positives = 19/46 (41%)

Query: 2    PAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPP 47
            P  P   +PPPPP+P     P      +     P  P  GI  PPP
Sbjct: 1100 PPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1145


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 74.3 bits (181), Expect = 4e-13
 Identities = 49/142 (34%), Positives = 65/142 (45%), Gaps = 18/142 (12%)

Query: 547 PSKPNEI-------PQQPPP--PSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVM 597
           P  PN +       P  PPP  P  A   P ++PP++    PP+  PP        VP  
Sbjct: 650 PQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPS 709

Query: 598 P--RPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIM-APRPPPMIVPTAFVP 654
           P   PPM+     PP +     PP + AP + V P PP++PP+  +  PPP + P    P
Sbjct: 710 PPASPPMSPSATPPPQA-----PPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAP 764

Query: 655 APPVAP-VPAPAPMPPVHPPPP 675
              V P  PA  PM P+  PPP
Sbjct: 765 PLQVPPSPPASLPMSPLAKPPP 786



 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 45/147 (30%), Positives = 65/147 (44%), Gaps = 19/147 (12%)

Query: 547 PSKPNEIPQQPPPP-------SSATNIPSSAP---PITSVPRPPTMPPP-VRTTVVSAVP 595
           P+ P   P   PPP       +    +P S P   P++ + +PP   PP + T  + A+P
Sbjct: 742 PASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALP 801

Query: 596 VMP-----RPPMASVVRLPPGSVIAP---MPPIIHAPRINVVPMPPSAPPIMAPRPPPMI 647
             P     + P +    LP   +  P    PP++ AP + V P PP++P + APR PP  
Sbjct: 802 SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTP 861

Query: 648 VPTAFVPAPPVAPVPAPAPMPPVHPPP 674
            P   V  P +    AP P PP    P
Sbjct: 862 GPDTSVSGPRLTLALAPGPPPPPSRSP 888



 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 52/164 (31%), Positives = 72/164 (43%), Gaps = 38/164 (23%)

Query: 547 PSKPNEIPQQPP--PPSSATNIPSS-------APPITSVPRPPTMPP--PVRTTVVSAVP 595
           PS P + P  PP  PP S +  P S       APP+   P PP  PP  P  T    A P
Sbjct: 669 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP 728

Query: 596 VMPRPPMASVVRLPPGSVIAP-------MPPIIHAPRINVVPMPPSAPPIMAP--RPPPM 646
            +  PP+      P    ++P       +PP++ AP + V P PP++ P M+P  +PPP 
Sbjct: 729 PLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLP-MSPLAKPPPQ 787

Query: 647 IVPTAFVPAPPVAPVPAP---------------APMPPVHPPPP 675
             P   +  PP+  +P+P                PM P+  PPP
Sbjct: 788 APPA--LATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPP 829



 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 46/140 (32%), Positives = 65/140 (46%), Gaps = 14/140 (10%)

Query: 547 PSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPP--PVRTTVVSAVPVMPRPPMAS 604
           P+ P   P   PPP +    P +APP+   P PP  PP  P  T      P++  PP+  
Sbjct: 711 PASPPMSPSATPPPQAPP--PLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPL-Q 767

Query: 605 VVRLPPGSV-IAPM-------PPIIHAPRINVVPMPPSAPPIMAPRPPPMIVP-TAFVPA 655
           V   PP S+ ++P+       PP +  P +  +P PP++ P  AP  P   +P +     
Sbjct: 768 VPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP 827

Query: 656 PPVAPVPAPAPMPPVHPPPP 675
           PP AP    AP+  V P PP
Sbjct: 828 PPQAPPVLAAPLLQVPPSPP 847



 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 83/395 (21%), Positives = 133/395 (33%), Gaps = 82/395 (20%)

Query: 364 EGQKVPPPPE--TPMPPPLPPTPDQVIVRKDYDPKASKP-----------LPPAPAPDEY 410
           + + VPPP    TP+P  LPP+P          P  S P            PP+ AP   
Sbjct: 313 KARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSM 372

Query: 411 LVSPITG----EKIPASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSL 466
              P+      + IP  ++   +    L          ++   Q+   + +P L    S 
Sbjct: 373 TTPPMQAPPSLQTIPPIQVPHSLTSPSLQA---PPSPLALSSLQATTSLGSPTLQATHSF 429

Query: 467 KQLAERRTDIFGVEETAIGKKIGEEE-IQKPEEKVTWDGHSGSMARTQQAAQANITLQEQ 525
             ++ R+T       +       +   +Q P           S++       + +T+   
Sbjct: 430 LTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHP- 488

Query: 526 IEAIHKAKGLVPEDDTKEKIGPSKPNEIPQQPP----PPSSAT-----NIPSSAPP---- 572
           ++A+       P+      I P    +    PP    PP+S T     N+PS APP    
Sbjct: 489 LQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQT 548

Query: 573 --------------------ITSVPRPPTMPPP-----VRTTVVSAVPVMPRPPMASVVR 607
                               + + P P T PPP     + T    A P +  PP+  +  
Sbjct: 549 ASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPS 608

Query: 608 LPPGSVIAP---MPPIIHAPRINVVPMPPSAPP-------------------IMAPRPPP 645
            P   +  P    PP +  P +   P PP++PP                   + AP  PP
Sbjct: 609 PPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP 668

Query: 646 MIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEP 680
              P     +PP +P  +P+  PP   PP +   P
Sbjct: 669 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPP 703



 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 51/157 (32%), Positives = 72/157 (45%), Gaps = 31/157 (19%)

Query: 547 PSKPNEIPQQPP--PPSSATNIPSSAPPITSVPRPPTMP---PPVRTTVVSAVPVMPRPP 601
           P  P+ I   PP  PP+ A+      PP+  +P PP  P   PP +     A+P +  PP
Sbjct: 581 PETPSSIATPPPQAPPALAS------PPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPP 634

Query: 602 MASVVRLPPGSVIA-PMPPIIHAPRINVVPMP---PSAPPIMAPRPPPM---IVPTAFVP 654
             S    PP S +A P P   +A  ++++  P   P +PP+ AP  PP    + P+A  P
Sbjct: 635 --SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPP 692

Query: 655 --------APPVAPVPAPAPMPPVHP---PPPMEDEP 680
                   APP+   P+P   PP+ P   PPP    P
Sbjct: 693 SQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP 729



 Score = 60.5 bits (145), Expect = 6e-09
 Identities = 49/174 (28%), Positives = 69/174 (39%), Gaps = 29/174 (16%)

Query: 506 SGSMARTQQAAQANITLQEQ--IEAIHKAKGLVPEDDTKEKIGPSKPNEIPQQPPPPSSA 563
           SG  AR    A A+ +  +   ++A+   +   P  D    +GP   +  P   P PS  
Sbjct: 255 SGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS--PLATPSPSGT 312

Query: 564 TNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHA 623
              P   P   + P P T+P              P PP+A+ + L P S  AP       
Sbjct: 313 KARPVPPPDNAATPLPATLP--------------PSPPLATPLPLAPPSPSAP------- 351

Query: 624 PRINVVPMPPSAPPIMAP---RPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPP 674
           P +  +P PP+ PP  AP     PPM  P +    PP+  VP     P +  PP
Sbjct: 352 PSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPI-QVPHSLTSPSLQAPP 404



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 45/153 (29%), Positives = 60/153 (39%), Gaps = 26/153 (16%)

Query: 554 PQQPP----PPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRP--------- 600
           PQ PP    PP  A   P ++PP++ +  P    P      +   P  P P         
Sbjct: 619 PQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFS 678

Query: 601 PMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAP 660
           P AS    P  +  +  PP + AP + V P PP++PP M+P   P          PP AP
Sbjct: 679 PPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPP-MSPSATP----------PPQAP 727

Query: 661 VPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
            P  AP  P+  PP     P      T    +P
Sbjct: 728 PPLAAP--PLQVPPSPPASPPMSPSATPPPRVP 758



 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 42/140 (30%), Positives = 55/140 (39%), Gaps = 24/140 (17%)

Query: 546 GPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASV 605
           GPS     P+ P  PS         P      RPP + PP R     A+  +   P+A+ 
Sbjct: 256 GPSARGT-PRAPAHPSQPK------PKGLQALRPPQVTPP-RKDAAPALGPLSSSPLATP 307

Query: 606 VRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAP----- 660
              P G+   P+PP    P     P+P + PP      PP+  P    P  P AP     
Sbjct: 308 S--PSGTKARPVPP----PDNAATPLPATLPP-----SPPLATPLPLAPPSPSAPPSLQT 356

Query: 661 VPAPAPMPPVHPPPPMEDEP 680
           +P+P   PP   PP M   P
Sbjct: 357 LPSPPATPPSQAPPSMTTPP 376



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 37/134 (27%), Positives = 52/134 (38%), Gaps = 22/134 (16%)

Query: 554 PQQPPPPSSATNIPSSAPPITSVPRPPTMPP-------PVRTTVVSAVPVMPRPPMASVV 606
           P QP P      + +  PP  + PR    P        P+ T   S     P PP  +  
Sbjct: 269 PSQPKPKG----LQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAA 324

Query: 607 RLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAP 666
             P  + + P PP+  A  + + P  PSAPP +   P P        PA P +  P    
Sbjct: 325 T-PLPATLPPSPPL--ATPLPLAPPSPSAPPSLQTLPSP--------PATPPSQAPPSMT 373

Query: 667 MPPVHPPPPMEDEP 680
            PP+  PP ++  P
Sbjct: 374 TPPMQAPPSLQTIP 387



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 91/397 (22%), Positives = 138/397 (34%), Gaps = 74/397 (18%)

Query: 365 GQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLP-----------PAPAPDEYLV- 412
           G   P PP +P PPP P TP  + V         KPL            P  AP      
Sbjct: 23  GLLTPRPPGSPRPPP-PVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTR 81

Query: 413 SPITGEKIPASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLK-QLAE 471
           S  T  + PAS+     R     P           +  S   V +PG    ++    L +
Sbjct: 82  SAGTSSRNPASRPPASGRGERAPPA----------KNTSPGPVSSPGRASGTTRPGPLGQ 131

Query: 472 RRTDIFGVEETAIGKKIGEEE-------IQKPEEKVTWDGHSGSMARTQQAAQANITLQE 524
           +   I   E  A GK     +        ++     T    S +MAR  +AA   + L  
Sbjct: 132 KGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPR 191

Query: 525 QIEAIHKAKGLVPEDDTKEKIGPSKPNEIPQQPPP----PSS--------ATNIPSSAPP 572
              +   A+   P +  ++ +  +  +   +  P     PS+        + ++ SSA P
Sbjct: 192 PAPS---ARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP 248

Query: 573 ITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPM- 631
           ++S  R  + P    T    A P  P+P     +R          PP +  PR +  P  
Sbjct: 249 LSSPAR--SGPSARGTPRAPAHPSQPKPKGLQALR----------PPQVTPPRKDAAPAL 296

Query: 632 -PPSAPPIMAPRP--------PPMIVPTAFVPA--PPVAPVPAPAPMPPVHPPPPMEDEP 680
            P S+ P+  P P        PP       +PA  PP  P+  P P+ P  P  P   + 
Sbjct: 297 GPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQT 356

Query: 681 TSKKLKTEDSLMPEEEFLRRNKGPVSIK----VQVPN 713
                 T  S  P        + P S++    +QVP+
Sbjct: 357 LPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPH 393



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 41/172 (23%), Positives = 60/172 (34%), Gaps = 34/172 (19%)

Query: 547 PSKPNEIPQQPPP----------PSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPV 596
           PS P   P Q PP          PS  T  P   P   + P     P P+  + + A   
Sbjct: 358 PSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTS 417

Query: 597 MPRPPMASV-------VRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVP 649
           +  P + +         R    S+ +P  P            PP +PP+ AP   P   P
Sbjct: 418 LGSPTLQATHSFLTMSPRQTQASLTSPSRP---------ASTPPDSPPLQAPLSLPASPP 468

Query: 650 TAFVPAPPVAPVPAPAPMPPV--------HPPPPMEDEPTSKKLKTEDSLMP 693
                +P V+P+ +P  + P+        H P           L+T+ SL P
Sbjct: 469 LQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAP 520


>gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3
           [Homo sapiens]
          Length = 1125

 Score = 72.0 bits (175), Expect = 2e-12
 Identities = 45/138 (32%), Positives = 61/138 (44%), Gaps = 14/138 (10%)

Query: 537 PEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPV 596
           PE++  +  G    +  P  P P      +P   PPI  VP P T+PPP         P 
Sbjct: 637 PENEVAQNGGAETSHTEPVSPIPKP----LPVPVPPIP-VPAPITVPPP------QVPPH 685

Query: 597 MPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAP 656
            P PP+   ++ P  +    +PP    P    VP PP  PP + P   PM +P  F+P  
Sbjct: 686 QPGPPVVGALQPPAFTPPLGIPPPGFGPG---VPPPPPPPPFLRPGFNPMHLPPGFLPPG 742

Query: 657 PVAPVPAPAPMPPVHPPP 674
           P  P+  P  +PP H PP
Sbjct: 743 PPPPITPPVSIPPPHTPP 760



 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 35/129 (27%), Positives = 44/129 (34%), Gaps = 30/129 (23%)

Query: 536 VPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVP 595
           VP       I    P   P QP             PP+    +PP   PP+        P
Sbjct: 666 VPPIPVPAPITVPPPQVPPHQP------------GPPVVGALQPPAFTPPLGIPPPGFGP 713

Query: 596 VMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPA 655
            +P PP              P PP +  P  N + +PP   P   P PPP I P   +P 
Sbjct: 714 GVPPPP--------------PPPPFLR-PGFNPMHLPPGFLP---PGPPPPITPPVSIPP 755

Query: 656 PPVAPVPAP 664
           P   P+  P
Sbjct: 756 PHTPPISIP 764



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 38/149 (25%), Positives = 60/149 (40%), Gaps = 19/149 (12%)

Query: 559 PPSSATNIPSS--APPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAP 616
           PP++ TN+P+     P++ +      P PV      +  ++   P    ++ PPG     
Sbjct: 788 PPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPG----- 842

Query: 617 MPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFV---------PAPPVAPVPAPAPM 667
           MPP  H  R  ++P  P  P +M   PPP   P  F          P PP  P   P  M
Sbjct: 843 MPPP-HLQRFPLMPPRPMPPHMMHRGPPPG--PGGFAMPPPHGMKGPFPPHGPFVRPGGM 899

Query: 668 PPVHPPPPMEDEPTSKKLKTEDSLMPEEE 696
           P +  P P    P  +  + +    P+++
Sbjct: 900 PGLGGPGPGPGGPEDRDGRQQPPQQPQQQ 928



 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 41/172 (23%), Positives = 62/172 (36%), Gaps = 32/172 (18%)

Query: 539 DDTKEKIGPSKPNEI-------PQQPPPPSSATNIPSSAPPITSVPRPPTMP-------- 583
           DD  E +  SK  +        P    PP+    +P++A P  + P PP  P        
Sbjct: 268 DDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGM 327

Query: 584 -PPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPR 642
             P  T   +     PR  M  + + P    + P+PP    P   ++P PP         
Sbjct: 328 QQPAYTQHQNMDQFQPR--MMGIQQDPMHHQV-PLPPNGQMPGFGLLPTPPF-------- 376

Query: 643 PPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMPE 694
            PPM  P      PP  PV  P          P+  +P  ++++ E   + E
Sbjct: 377 -PPMAQPV----IPPTPPVQQPFQASFQAQNEPLTQKPHQQEMEVEQPCIQE 423



 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 48/196 (24%), Positives = 64/196 (32%), Gaps = 52/196 (26%)

Query: 532 AKGLVPEDDTKEKIG----PSKPNEIPQQP--------------PPPSSATNIPSSA--- 570
           A+G     D+ +  G    P+ P  +P  P              P P      PS+    
Sbjct: 770 ARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLG 829

Query: 571 --PPITSVPRPPTMPPPVRTTVVSAVPVMPRPPM-------------ASVVRLPPGSVIA 615
             P +  + RPP MPPP     +   P+MP  PM                   PP  +  
Sbjct: 830 ARPGLIPLQRPPGMPPP----HLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKG 885

Query: 616 PMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHP--- 672
           P PP  H P +    MP    P   P  P           PP  P   P P  P  P   
Sbjct: 886 PFPP--HGPFVRPGGMPGLGGPGPGPGGPE---DRDGRQQPPQQPQQQPQPQAPQQPQQQ 940

Query: 673 ----PPPMEDEPTSKK 684
               PPP +  P +++
Sbjct: 941 QQQQPPPSQQPPPTQQ 956



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 37/130 (28%), Positives = 52/130 (40%), Gaps = 41/130 (31%)

Query: 547 PSKP-NEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASV 605
           P KP NE+ Q     +S T       P++ +P+P  +P PV           P  P+ + 
Sbjct: 634 PKKPENEVAQNGGAETSHTE------PVSPIPKP--LPVPV-----------PPIPVPAP 674

Query: 606 VRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPA 665
           + +PP  V    PP  H P           PP++    PP   P   +P P   P     
Sbjct: 675 ITVPPPQV----PP--HQP----------GPPVVGALQPPAFTPPLGIPPPGFGP----- 713

Query: 666 PMPPVHPPPP 675
            +PP  PPPP
Sbjct: 714 GVPPPPPPPP 723



 Score = 32.3 bits (72), Expect = 1.8
 Identities = 17/40 (42%), Positives = 20/40 (50%), Gaps = 8/40 (20%)

Query: 641 PRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEP 680
           P+P P       VP PP+ PVPAP  +PP   PP     P
Sbjct: 659 PKPLP-------VPVPPI-PVPAPITVPPPQVPPHQPGPP 690



 Score = 31.6 bits (70), Expect = 3.0
 Identities = 17/42 (40%), Positives = 21/42 (50%), Gaps = 4/42 (9%)

Query: 368 VPPPPETPMPPPLPPTPDQVIVRKDYDPKASKP--LPPAPAP 407
           +PPP   P  PP PP P    +R  ++P    P  LPP P P
Sbjct: 706 IPPPGFGPGVPPPPPPPP--FLRPGFNPMHLPPGFLPPGPPP 745



 Score = 31.2 bits (69), Expect = 3.9
 Identities = 18/49 (36%), Positives = 25/49 (51%), Gaps = 8/49 (16%)

Query: 100 EFKEGKAQEPSAAIPKVMQQQQQTTQQQLPQKVQAQVIQETIVPKEPPP 148
           E ++G+ Q P        QQ QQ  Q Q PQ+ Q Q  Q+    ++PPP
Sbjct: 913 EDRDGRQQPP--------QQPQQQPQPQAPQQPQQQQQQQPPPSQQPPP 953



 Score = 30.0 bits (66), Expect = 8.8
 Identities = 16/45 (35%), Positives = 18/45 (40%), Gaps = 3/45 (6%)

Query: 5   PVQAVPPPPPVPTEP---KQPTEEEASSKEDSAPSKPVVGIIYPP 46
           PV  +P P PVP  P     P            P  PVVG + PP
Sbjct: 654 PVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPP 698


>gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2
           [Homo sapiens]
          Length = 1132

 Score = 72.0 bits (175), Expect = 2e-12
 Identities = 45/138 (32%), Positives = 61/138 (44%), Gaps = 14/138 (10%)

Query: 537 PEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPV 596
           PE++  +  G    +  P  P P      +P   PPI  VP P T+PPP         P 
Sbjct: 622 PENEVAQNGGAETSHTEPVSPIPKP----LPVPVPPIP-VPAPITVPPP------QVPPH 670

Query: 597 MPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAP 656
            P PP+   ++ P  +    +PP    P    VP PP  PP + P   PM +P  F+P  
Sbjct: 671 QPGPPVVGALQPPAFTPPLGIPPPGFGPG---VPPPPPPPPFLRPGFNPMHLPPGFLPPG 727

Query: 657 PVAPVPAPAPMPPVHPPP 674
           P  P+  P  +PP H PP
Sbjct: 728 PPPPITPPVSIPPPHTPP 745



 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 35/129 (27%), Positives = 44/129 (34%), Gaps = 30/129 (23%)

Query: 536 VPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVP 595
           VP       I    P   P QP             PP+    +PP   PP+        P
Sbjct: 651 VPPIPVPAPITVPPPQVPPHQP------------GPPVVGALQPPAFTPPLGIPPPGFGP 698

Query: 596 VMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPA 655
            +P PP              P PP +  P  N + +PP   P   P PPP I P   +P 
Sbjct: 699 GVPPPP--------------PPPPFLR-PGFNPMHLPPGFLP---PGPPPPITPPVSIPP 740

Query: 656 PPVAPVPAP 664
           P   P+  P
Sbjct: 741 PHTPPISIP 749



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 38/149 (25%), Positives = 60/149 (40%), Gaps = 19/149 (12%)

Query: 559 PPSSATNIPSS--APPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAP 616
           PP++ TN+P+     P++ +      P PV      +  ++   P    ++ PPG     
Sbjct: 795 PPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPG----- 849

Query: 617 MPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFV---------PAPPVAPVPAPAPM 667
           MPP  H  R  ++P  P  P +M   PPP   P  F          P PP  P   P  M
Sbjct: 850 MPPP-HLQRFPLMPPRPMPPHMMHRGPPPG--PGGFAMPPPHGMKGPFPPHGPFVRPGGM 906

Query: 668 PPVHPPPPMEDEPTSKKLKTEDSLMPEEE 696
           P +  P P    P  +  + +    P+++
Sbjct: 907 PGLGGPGPGPGGPEDRDGRQQPPQQPQQQ 935



 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 41/172 (23%), Positives = 62/172 (36%), Gaps = 32/172 (18%)

Query: 539 DDTKEKIGPSKPNEI-------PQQPPPPSSATNIPSSAPPITSVPRPPTMP-------- 583
           DD  E +  SK  +        P    PP+    +P++A P  + P PP  P        
Sbjct: 253 DDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGM 312

Query: 584 -PPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPR 642
             P  T   +     PR  M  + + P    + P+PP    P   ++P PP         
Sbjct: 313 QQPAYTQHQNMDQFQPR--MMGIQQDPMHHQV-PLPPNGQMPGFGLLPTPPF-------- 361

Query: 643 PPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMPE 694
            PPM  P      PP  PV  P          P+  +P  ++++ E   + E
Sbjct: 362 -PPMAQPV----IPPTPPVQQPFQASFQAQNEPLTQKPHQQEMEVEQPCIQE 408



 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 48/196 (24%), Positives = 64/196 (32%), Gaps = 52/196 (26%)

Query: 532 AKGLVPEDDTKEKIG----PSKPNEIPQQP--------------PPPSSATNIPSSA--- 570
           A+G     D+ +  G    P+ P  +P  P              P P      PS+    
Sbjct: 777 ARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLG 836

Query: 571 --PPITSVPRPPTMPPPVRTTVVSAVPVMPRPPM-------------ASVVRLPPGSVIA 615
             P +  + RPP MPPP     +   P+MP  PM                   PP  +  
Sbjct: 837 ARPGLIPLQRPPGMPPPH----LQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKG 892

Query: 616 PMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHP--- 672
           P PP  H P +    MP    P   P  P           PP  P   P P  P  P   
Sbjct: 893 PFPP--HGPFVRPGGMPGLGGPGPGPGGPE---DRDGRQQPPQQPQQQPQPQAPQQPQQQ 947

Query: 673 ----PPPMEDEPTSKK 684
               PPP +  P +++
Sbjct: 948 QQQQPPPSQQPPPTQQ 963



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 37/130 (28%), Positives = 52/130 (40%), Gaps = 41/130 (31%)

Query: 547 PSKP-NEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASV 605
           P KP NE+ Q     +S T       P++ +P+P  +P PV           P  P+ + 
Sbjct: 619 PKKPENEVAQNGGAETSHTE------PVSPIPKP--LPVPV-----------PPIPVPAP 659

Query: 606 VRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPA 665
           + +PP  V    PP  H P           PP++    PP   P   +P P   P     
Sbjct: 660 ITVPPPQV----PP--HQP----------GPPVVGALQPPAFTPPLGIPPPGFGP----- 698

Query: 666 PMPPVHPPPP 675
            +PP  PPPP
Sbjct: 699 GVPPPPPPPP 708



 Score = 32.3 bits (72), Expect = 1.8
 Identities = 17/40 (42%), Positives = 20/40 (50%), Gaps = 8/40 (20%)

Query: 641 PRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEP 680
           P+P P       VP PP+ PVPAP  +PP   PP     P
Sbjct: 644 PKPLP-------VPVPPI-PVPAPITVPPPQVPPHQPGPP 675



 Score = 31.6 bits (70), Expect = 3.0
 Identities = 17/42 (40%), Positives = 21/42 (50%), Gaps = 4/42 (9%)

Query: 368 VPPPPETPMPPPLPPTPDQVIVRKDYDPKASKP--LPPAPAP 407
           +PPP   P  PP PP P    +R  ++P    P  LPP P P
Sbjct: 691 IPPPGFGPGVPPPPPPPP--FLRPGFNPMHLPPGFLPPGPPP 730



 Score = 31.2 bits (69), Expect = 3.9
 Identities = 18/49 (36%), Positives = 25/49 (51%), Gaps = 8/49 (16%)

Query: 100 EFKEGKAQEPSAAIPKVMQQQQQTTQQQLPQKVQAQVIQETIVPKEPPP 148
           E ++G+ Q P        QQ QQ  Q Q PQ+ Q Q  Q+    ++PPP
Sbjct: 920 EDRDGRQQPP--------QQPQQQPQPQAPQQPQQQQQQQPPPSQQPPP 960



 Score = 30.0 bits (66), Expect = 8.8
 Identities = 16/45 (35%), Positives = 18/45 (40%), Gaps = 3/45 (6%)

Query: 5   PVQAVPPPPPVPTEP---KQPTEEEASSKEDSAPSKPVVGIIYPP 46
           PV  +P P PVP  P     P            P  PVVG + PP
Sbjct: 639 PVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPP 683


>gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1
           [Homo sapiens]
          Length = 1147

 Score = 72.0 bits (175), Expect = 2e-12
 Identities = 45/138 (32%), Positives = 61/138 (44%), Gaps = 14/138 (10%)

Query: 537 PEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPV 596
           PE++  +  G    +  P  P P      +P   PPI  VP P T+PPP         P 
Sbjct: 637 PENEVAQNGGAETSHTEPVSPIPKP----LPVPVPPIP-VPAPITVPPP------QVPPH 685

Query: 597 MPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAP 656
            P PP+   ++ P  +    +PP    P    VP PP  PP + P   PM +P  F+P  
Sbjct: 686 QPGPPVVGALQPPAFTPPLGIPPPGFGPG---VPPPPPPPPFLRPGFNPMHLPPGFLPPG 742

Query: 657 PVAPVPAPAPMPPVHPPP 674
           P  P+  P  +PP H PP
Sbjct: 743 PPPPITPPVSIPPPHTPP 760



 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 35/129 (27%), Positives = 44/129 (34%), Gaps = 30/129 (23%)

Query: 536 VPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVP 595
           VP       I    P   P QP             PP+    +PP   PP+        P
Sbjct: 666 VPPIPVPAPITVPPPQVPPHQP------------GPPVVGALQPPAFTPPLGIPPPGFGP 713

Query: 596 VMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPA 655
            +P PP              P PP +  P  N + +PP   P   P PPP I P   +P 
Sbjct: 714 GVPPPP--------------PPPPFLR-PGFNPMHLPPGFLP---PGPPPPITPPVSIPP 755

Query: 656 PPVAPVPAP 664
           P   P+  P
Sbjct: 756 PHTPPISIP 764



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 38/149 (25%), Positives = 60/149 (40%), Gaps = 19/149 (12%)

Query: 559 PPSSATNIPSS--APPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAP 616
           PP++ TN+P+     P++ +      P PV      +  ++   P    ++ PPG     
Sbjct: 810 PPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPG----- 864

Query: 617 MPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFV---------PAPPVAPVPAPAPM 667
           MPP  H  R  ++P  P  P +M   PPP   P  F          P PP  P   P  M
Sbjct: 865 MPPP-HLQRFPLMPPRPMPPHMMHRGPPPG--PGGFAMPPPHGMKGPFPPHGPFVRPGGM 921

Query: 668 PPVHPPPPMEDEPTSKKLKTEDSLMPEEE 696
           P +  P P    P  +  + +    P+++
Sbjct: 922 PGLGGPGPGPGGPEDRDGRQQPPQQPQQQ 950



 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 41/172 (23%), Positives = 62/172 (36%), Gaps = 32/172 (18%)

Query: 539 DDTKEKIGPSKPNEI-------PQQPPPPSSATNIPSSAPPITSVPRPPTMP-------- 583
           DD  E +  SK  +        P    PP+    +P++A P  + P PP  P        
Sbjct: 268 DDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGM 327

Query: 584 -PPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPR 642
             P  T   +     PR  M  + + P    + P+PP    P   ++P PP         
Sbjct: 328 QQPAYTQHQNMDQFQPR--MMGIQQDPMHHQV-PLPPNGQMPGFGLLPTPPF-------- 376

Query: 643 PPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMPE 694
            PPM  P      PP  PV  P          P+  +P  ++++ E   + E
Sbjct: 377 -PPMAQPV----IPPTPPVQQPFQASFQAQNEPLTQKPHQQEMEVEQPCIQE 423



 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 48/196 (24%), Positives = 64/196 (32%), Gaps = 52/196 (26%)

Query: 532 AKGLVPEDDTKEKIG----PSKPNEIPQQP--------------PPPSSATNIPSSA--- 570
           A+G     D+ +  G    P+ P  +P  P              P P      PS+    
Sbjct: 792 ARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLG 851

Query: 571 --PPITSVPRPPTMPPPVRTTVVSAVPVMPRPPM-------------ASVVRLPPGSVIA 615
             P +  + RPP MPPP     +   P+MP  PM                   PP  +  
Sbjct: 852 ARPGLIPLQRPPGMPPPH----LQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKG 907

Query: 616 PMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHP--- 672
           P PP  H P +    MP    P   P  P           PP  P   P P  P  P   
Sbjct: 908 PFPP--HGPFVRPGGMPGLGGPGPGPGGPE---DRDGRQQPPQQPQQQPQPQAPQQPQQQ 962

Query: 673 ----PPPMEDEPTSKK 684
               PPP +  P +++
Sbjct: 963 QQQQPPPSQQPPPTQQ 978



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 37/130 (28%), Positives = 52/130 (40%), Gaps = 41/130 (31%)

Query: 547 PSKP-NEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASV 605
           P KP NE+ Q     +S T       P++ +P+P  +P PV           P  P+ + 
Sbjct: 634 PKKPENEVAQNGGAETSHTE------PVSPIPKP--LPVPV-----------PPIPVPAP 674

Query: 606 VRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPA 665
           + +PP  V    PP  H P           PP++    PP   P   +P P   P     
Sbjct: 675 ITVPPPQV----PP--HQP----------GPPVVGALQPPAFTPPLGIPPPGFGP----- 713

Query: 666 PMPPVHPPPP 675
            +PP  PPPP
Sbjct: 714 GVPPPPPPPP 723



 Score = 32.3 bits (72), Expect = 1.8
 Identities = 17/40 (42%), Positives = 20/40 (50%), Gaps = 8/40 (20%)

Query: 641 PRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEP 680
           P+P P       VP PP+ PVPAP  +PP   PP     P
Sbjct: 659 PKPLP-------VPVPPI-PVPAPITVPPPQVPPHQPGPP 690



 Score = 31.6 bits (70), Expect = 3.0
 Identities = 17/42 (40%), Positives = 21/42 (50%), Gaps = 4/42 (9%)

Query: 368 VPPPPETPMPPPLPPTPDQVIVRKDYDPKASKP--LPPAPAP 407
           +PPP   P  PP PP P    +R  ++P    P  LPP P P
Sbjct: 706 IPPPGFGPGVPPPPPPPP--FLRPGFNPMHLPPGFLPPGPPP 745



 Score = 31.2 bits (69), Expect = 3.9
 Identities = 18/49 (36%), Positives = 25/49 (51%), Gaps = 8/49 (16%)

Query: 100 EFKEGKAQEPSAAIPKVMQQQQQTTQQQLPQKVQAQVIQETIVPKEPPP 148
           E ++G+ Q P        QQ QQ  Q Q PQ+ Q Q  Q+    ++PPP
Sbjct: 935 EDRDGRQQPP--------QQPQQQPQPQAPQQPQQQQQQQPPPSQQPPP 975



 Score = 30.0 bits (66), Expect = 8.8
 Identities = 16/45 (35%), Positives = 18/45 (40%), Gaps = 3/45 (6%)

Query: 5   PVQAVPPPPPVPTEP---KQPTEEEASSKEDSAPSKPVVGIIYPP 46
           PV  +P P PVP  P     P            P  PVVG + PP
Sbjct: 654 PVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPP 698


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score = 72.0 bits (175), Expect = 2e-12
 Identities = 91/370 (24%), Positives = 124/370 (33%), Gaps = 96/370 (25%)

Query: 358 GSDDEEEGQKVPPPP----------ETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAP 407
           G+ D  E ++ P PP          E P  PP PP PD   +     P       P  +P
Sbjct: 421 GARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSP 480

Query: 408 DE-YLVSPITGEKIPASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSL 466
               L S   G + P   +   + + L + R    +   +RE  SD E+   G  I SS 
Sbjct: 481 GTPTLESSPAGPEKPHDSLDSRIEMLLKEQR---TKLLFLREPDSDTELQMEGSPISSSS 537

Query: 467 KQLAERRTDIFGVEETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQI 526
            QL+                         P      +   G    T  +++ + T  E I
Sbjct: 538 SQLS-------------------------PLAPFGTNSQPGFRGPTPPSSRPSSTGLEDI 572

Query: 527 EAIHKAKGLVPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAP--------------- 571
                    +P+ D  E++        P +P PP  A  +  +A                
Sbjct: 573 SPTP-----LPDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEK 627

Query: 572 ----------------------PITSV--PRPPTMPPPVRTTVVSAV--PVMPRPPMASV 605
                                 PITS   P+P  + P        +V  P +P PP    
Sbjct: 628 MDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPP---- 683

Query: 606 VRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPA 665
              PPG    P PP    P+    PMPP  PP   P PPP   P   VP PP+ P P   
Sbjct: 684 ---PPGFPPLPPPPPPPPPQPG-FPMPPPLPP--PPPPPPPAHPAVTVPPPPL-PAPPGV 736

Query: 666 PMPPVHPPPP 675
           P PP+ PP P
Sbjct: 737 PPPPILPPLP 746



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 99/424 (23%), Positives = 144/424 (33%), Gaps = 56/424 (13%)

Query: 259  KEEEEKEKERVAYAQIDWHDFVVVETVDFQPNEQGNFPPPTTPEELGA------RILIQE 312
            +E+EE E+ER      D  D    E     P   G    P  P EL +      +  + E
Sbjct: 989  EEDEESERER----DRDMAD-TPCELAKRDPKGVGVRRRPARPLELDSGGEEDEKESLSE 1043

Query: 313  RYEKFGESEEVEMEVESDEEDDKQEKAEEPPSQLDQDT---QVQDMDEGSDDEEEGQKVP 369
              E   E EE E E E +++DD      +     D+DT   +  + DEG  DEEE   + 
Sbjct: 1044 EQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEEETVSI- 1102

Query: 370  PPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKMQEHM 429
                  +      T             +S+  P +   +E +V+    E+    +M    
Sbjct: 1103 ------VTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEE 1156

Query: 430  RIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGVEETAIGKKIG 489
             +    P   EQ          ++   APG     SL    E   DI             
Sbjct: 1157 SMASAGPEDFEQ--------DGEEAALAPGAPAVDSLGM--EEEVDI------------- 1193

Query: 490  EEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKAKGLVPEDDTKEKIG--P 547
            E E   PEE+ +           ++ A +    +E   +   A  L PE   KE     P
Sbjct: 1194 ETEAVAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPP 1253

Query: 548  SKPNEIPQQ----PPPPSSATNIPSSAP-PITSVPRPPTMPPPVRTTVVSAVPVMPRPPM 602
              P   P+      P P     +P   P P    PRPP+ PP   TT  S   V P P  
Sbjct: 1254 LSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLA 1313

Query: 603  ASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVP 662
                   PG        +  +     VP  P   P ++     + + +  VP  P +  P
Sbjct: 1314 EDHPPHTPGL----CGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFS-YP 1368

Query: 663  APAP 666
            AP+P
Sbjct: 1369 APSP 1372



 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 112/474 (23%), Positives = 168/474 (35%), Gaps = 76/474 (16%)

Query: 257  RKKEEEEKEKERVAYAQIDWHDFVVVETVDFQPNEQGNFPPPTTPEELGARILIQERYEK 316
            R++EEEE+E+E VA   +           DF+ + +     P  P             + 
Sbjct: 1141 REEEEEEEEEEMVAEESM-----ASAGPEDFEQDGEEAALAPGAPA-----------VDS 1184

Query: 317  FGESEEVEMEVESDEEDDKQEKAEEPPSQL--DQDTQVQDMDEGSDDEEEGQKV----PP 370
             G  EEV++E E+   +++    +EPP  +  ++    ++  E     +EG  +    PP
Sbjct: 1185 LGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPP 1244

Query: 371  PPETPMPPPLPP--TPDQVIVRKDYDPKASKPLP-----PAPAPDEYLVSPITGEKIPAS 423
              E    PPL P   P+  +   + +P    PLP     P P P      P   E   AS
Sbjct: 1245 AKEVEARPPLSPERAPEHDL-EVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDAS 1303

Query: 424  KMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGVEETA 483
                      + P  L +          D   + PGL    +  Q  E      G E   
Sbjct: 1304 HPS-------VPPEPLAE----------DHPPHTPGLCGSLAKSQSTETVPATPGGEPPL 1346

Query: 484  IGKKIGEE--EIQKPEEKVTWDG-----HSGSMARTQ-QAAQANITLQEQIEAIHKAKGL 535
             G   G      Q P    ++        SG + RT  +      T  E    +      
Sbjct: 1347 SGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCP 1406

Query: 536  VPEDDTKEKIGPSKPNEIPQQ--PPPPSSATNIPSSAPPITSVP-RPPT-MPPPVRTTVV 591
            +P     E+ GP     + +   P P      +P + P +     R PT +PP +   + 
Sbjct: 1407 LPTGRRDERSGPLASPVLLETGLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLA 1466

Query: 592  SAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVV----------PMPPSAPPIMAP 641
            S  P M R P     R  P S+++   P++  P    +          P  P  P    P
Sbjct: 1467 SCPPPMKRKPGRP--RRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPSTHDP 1524

Query: 642  RPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMPEE 695
            R   +    A +PAPP    P P P P   PPPP+  EPT    K  D+  P E
Sbjct: 1525 RTVTLDFRNAGIPAPPPPLPPQPPPPP---PPPPV--EPTKLPFKELDNQWPSE 1573



 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 86/354 (24%), Positives = 119/354 (33%), Gaps = 63/354 (17%)

Query: 296 PPPTTPEELGARILIQERYEKFGESEEVEMEVESDEEDDKQEKAEEPPSQLD-------- 347
           PP T   ELG R         FG S E      +   +      E+P   LD        
Sbjct: 456 PPDTNSMELGGR-------PTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLK 508

Query: 348 -QDTQVQDMDE-GSDDEEEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAP 405
            Q T++  + E  SD E + +  P    +    PL P         +  P    P PP+ 
Sbjct: 509 EQRTKLLFLREPDSDTELQMEGSPISSSSSQLSPLAP------FGTNSQPGFRGPTPPSS 562

Query: 406 APDEYLVSPITGEKIPASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESS 465
            P    +  I+   +P S   E + +GL  PR                E   P  D    
Sbjct: 563 RPSSTGLEDISPTPLPDSDEDEELDLGL-GPR-------------PPPEPGPP--DPAGL 606

Query: 466 LKQLAERRTDIFGVEETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQ 525
           L Q AE   D+ G + T   +K+ E +    E+    D    S   T       + +   
Sbjct: 607 LSQTAEVALDLVG-DRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPG 665

Query: 526 IEAIHKAKGLVPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPP 585
             A+     L P   T     P     +P  PPPP      P   P    +P PP  PPP
Sbjct: 666 AAAVAAPSVLAP---TLPLPPPPGFPPLPPPPPPPPPQPGFPMPPP----LPPPPPPPPP 718

Query: 586 VRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIM 639
               V    P +P PP      +PP  ++ P+P           P PP   P+M
Sbjct: 719 AHPAVTVPPPPLPAPP-----GVPPPPILPPLP-----------PFPPGLFPVM 756



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 73/374 (19%), Positives = 131/374 (35%), Gaps = 44/374 (11%)

Query: 338  KAEEPPS--------QLDQDTQVQDMDEGSDDEEEGQKVPPPPETPMPPPLPPTPDQVIV 389
            K +EPP         +L   T V + DE S+ E +      P E     P       V V
Sbjct: 965  KRKEPPDTTSSGDQKRLRPSTSVDEEDEESERERDRDMADTPCELAKRDP-----KGVGV 1019

Query: 390  RKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKMQEHMRIGLLDPRWLEQRDRSIREK 449
            R+    + ++PL      +E     ++ E+    + +E            E+ +    + 
Sbjct: 1020 RR----RPARPLELDSGGEEDEKESLSEEQESTEEEEEAEE---------EEEEEDDDDD 1066

Query: 450  QSDDEVYAPGLDIESSLKQLAERRTDIFGVEETAIGKKIGEEEIQKPEEKVTWDGHSGSM 509
             SDD   +   D +++L + +E+       EET          I   + + T    S   
Sbjct: 1067 DSDDRDESENDDEDTALSEASEKDEGDSDEEETV--------SIVTSKAEATSSSESSES 1118

Query: 510  ARTQQAAQANITLQEQIEAIHKAKGLVPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSS 569
            +  + +++++ +  E  E +   +    E++ +     S  +  P+          +   
Sbjct: 1119 SEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEAALAPG 1178

Query: 570  APPITSVPRPPTMPPPVRTTVVSAVPVM-PRPPMASVVRLPPGSVIAPMPP-IIHAPRIN 627
            AP + S+     +            P M   PP+   V  P  S   P  P +     + 
Sbjct: 1179 APAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAML 1238

Query: 628  VVPMPPSA-----PPIMAPRPPPMIVPTAFVPAPPVA-PVPAPAPMPPVHPPPPMEDEPT 681
            + P PP+      PP+   R P   +     P PP+  P+P   P+PP  PP P    P 
Sbjct: 1239 LSPEPPAKEVEARPPLSPERAPEHDLEVE--PEPPMMLPLPLQPPLPPPRPPRPPSPPPE 1296

Query: 682  SKKLKTEDSLMPEE 695
             +        +P E
Sbjct: 1297 PETTDASHPSVPPE 1310



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 39/158 (24%), Positives = 55/158 (34%), Gaps = 29/158 (18%)

Query: 547  PSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P  P  +   PPP       P  +PP       P + PP    +   + ++P  P     
Sbjct: 1459 PLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQ---- 1514

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP----PSAPPIMAPRPPPMIVPTAFVPAPPVAPVP 662
                     P+ P  H PR   +       P+ PP + P+PPP        P PPV P  
Sbjct: 1515 --------TPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPP------PPPPPVEPTK 1560

Query: 663  APA-------PMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
             P        P   + P P   DE T + ++   S  P
Sbjct: 1561 LPFKELDNQWPSEAIPPGPRGRDEVTEEYMELAKSRGP 1598



 Score = 34.7 bits (78), Expect = 0.36
 Identities = 19/50 (38%), Positives = 24/50 (48%), Gaps = 4/50 (8%)

Query: 360  DDEEEGQKVPPPPETPMPPPLPPTPDQVIVR---KDYDPK-ASKPLPPAP 405
            D    G   PPPP  P PPP PP P     +   K+ D +  S+ +PP P
Sbjct: 1530 DFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPPGP 1579



 Score = 34.3 bits (77), Expect = 0.46
 Identities = 31/112 (27%), Positives = 36/112 (32%), Gaps = 21/112 (18%)

Query: 568 SSAPPITSVPRPPTM----PPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHA 623
           SS PP  + P+        PPP + T          P    V   PP     P  P   A
Sbjct: 363 SSGPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPP----PPEEPTATA 418

Query: 624 PRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPP 675
                     S     AP PPP+         PP  P+    P  P  PPPP
Sbjct: 419 ----AFGARDSGEFRRAPAPPPL---------PPAEPLAKEKPGTPPGPPPP 457



 Score = 33.9 bits (76), Expect = 0.61
 Identities = 40/188 (21%), Positives = 57/188 (30%), Gaps = 59/188 (31%)

Query: 288 QPNEQGNFPPPTTPEELGARILIQERYEKFGESEEVEMEVESDEEDDKQEKAEEPPSQLD 347
           QP  +G  PP + P   G   +         E EE+++ +        +    +P   L 
Sbjct: 551 QPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGL--GPRPPPEPGPPDPAGLLS 608

Query: 348 QDTQV------------QDMDEG----------SDDEEEGQKV----------------- 368
           Q  +V            + MDEG          SDDE     +                 
Sbjct: 609 QTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAA 668

Query: 369 --------------PPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSP 414
                         PPP   P+PPP PP P Q      +      P PP P P  +    
Sbjct: 669 VAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQ----PGFPMPPPLPPPPPPPPPAHPAVT 724

Query: 415 ITGEKIPA 422
           +    +PA
Sbjct: 725 VPPPPLPA 732


>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
           sapiens]
          Length = 505

 Score = 71.6 bits (174), Expect = 3e-12
 Identities = 47/135 (34%), Positives = 56/135 (41%), Gaps = 25/135 (18%)

Query: 551 NEIPQQ---PPPPSSATNIPSSAPPITSVPRPPTM-------PPPVRTTVVSAVPVMPRP 600
           NE+ +Q   PPPPS     P   PP  S P PP         PPP R    +  P  P  
Sbjct: 270 NELRRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSR 329

Query: 601 PMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAP 660
           P  +V   PP  +  P PP +           PS+ P   P PPP ++    V  PP   
Sbjct: 330 PSVAVPPPPPNRMYPPPPPAL-----------PSSAPSGPPPPPPSVLGVGPVAPPP--- 375

Query: 661 VPAPAPMPPVHPPPP 675
            P P P PP  PPPP
Sbjct: 376 -PPPPPPPPGPPPPP 389



 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 46/147 (31%), Positives = 58/147 (39%), Gaps = 17/147 (11%)

Query: 529 IHKAKGLVPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRT 588
           I K  G+    +   +  P  P      PPPP    +  S  PP  +  R    PPP R 
Sbjct: 259 IEKTGGVEAVKNELRRQAPPPPPPSRGGPPPPPPPPH-NSGPPPPPARGRGAPPPPPSRA 317

Query: 589 TVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIV 648
              +  P  P  P  +V   PP  +  P PP +           PS+ P   P PPP ++
Sbjct: 318 PTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPAL-----------PSSAPSGPPPPPPSVL 366

Query: 649 PTAFVPAPPVAPVPAPAPMPPVHPPPP 675
                   PVAP P P P PP  PPPP
Sbjct: 367 GVG-----PVAPPPPPPPPPPPGPPPP 388



 Score = 34.3 bits (77), Expect = 0.46
 Identities = 19/49 (38%), Positives = 23/49 (46%), Gaps = 3/49 (6%)

Query: 2   PAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPV---VGIIYPPP 47
           P+ P  AVPPPPP    P  P    +S+     P  P    VG + PPP
Sbjct: 327 PSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPP 375



 Score = 32.3 bits (72), Expect = 1.8
 Identities = 16/49 (32%), Positives = 22/49 (44%), Gaps = 3/49 (6%)

Query: 2   PAGPVQAVPPPPPV---PTEPKQPTEEEASSKEDSAPSKPVVGIIYPPP 47
           P  P  + PPPPP       P  P+    ++     PS+P V +  PPP
Sbjct: 291 PPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPP 339



 Score = 32.0 bits (71), Expect = 2.3
 Identities = 12/20 (60%), Positives = 12/20 (60%)

Query: 365 GQKVPPPPETPMPPPLPPTP 384
           G   PPPP  P PPP PP P
Sbjct: 369 GPVAPPPPPPPPPPPGPPPP 388



 Score = 31.6 bits (70), Expect = 3.0
 Identities = 17/42 (40%), Positives = 20/42 (47%), Gaps = 3/42 (7%)

Query: 547 PSKPNEIPQ-QPPPPSSATNIPSSAPPITSVPRPP--TMPPP 585
           P+ P+  P   PPPP S   +   APP    P PP    PPP
Sbjct: 348 PALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGPPPPP 389



 Score = 31.2 bits (69), Expect = 3.9
 Identities = 19/52 (36%), Positives = 20/52 (38%), Gaps = 12/52 (23%)

Query: 368 VPPPPET---PMPPPL---------PPTPDQVIVRKDYDPKASKPLPPAPAP 407
           VPPPP     P PPP          PP P  V+      P    P PP P P
Sbjct: 334 VPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGP 385



 Score = 30.4 bits (67), Expect = 6.7
 Identities = 17/44 (38%), Positives = 20/44 (45%), Gaps = 4/44 (9%)

Query: 365 GQKVPPPP----ETPMPPPLPPTPDQVIVRKDYDPKASKPLPPA 404
           G+  PPPP     T  PPP PP+   V V      +   P PPA
Sbjct: 306 GRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPA 349



 Score = 30.0 bits (66), Expect = 8.8
 Identities = 18/63 (28%), Positives = 23/63 (36%), Gaps = 8/63 (12%)

Query: 369 PPPPETPMPPPLP--------PTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKI 420
           PPPP    PPP P        P P +        P  S+P    P P    + P     +
Sbjct: 291 PPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPAL 350

Query: 421 PAS 423
           P+S
Sbjct: 351 PSS 353


>gi|47132519 Ras association and pleckstrin homology domains 1
           isoform 1 [Homo sapiens]
          Length = 1250

 Score = 71.6 bits (174), Expect = 3e-12
 Identities = 85/355 (23%), Positives = 126/355 (35%), Gaps = 68/355 (19%)

Query: 368 VPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKMQ- 426
           +PPPP  P PPP PP P               PLP   AP     +P+  +    +++Q 
Sbjct: 628 LPPPPPPPPPPPPPPPPPP------------PPLPSQSAPSAGSAAPMFVKYSTITRLQN 675

Query: 427 --EH------------MRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAER 472
             +H            M+   + P+ L   +  +           PG    S++ QL   
Sbjct: 676 ASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPG----SAMAQL--- 728

Query: 473 RTDIFGVEETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKA 532
                  +       + +     P  K+    H   +A         I      +A  K 
Sbjct: 729 -------KPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKP 781

Query: 533 KGLVPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPV------ 586
              +P   + + + P      P  P PP        + P     P PPT P PV      
Sbjct: 782 LVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLP 841

Query: 587 -RTTVVSAVPVMPRPPMASVVR-----LPPGSVIAPMPPIIHAPRINVVP--MPPSAPPI 638
            + +  +  P  P  P+ SVV+      PP     P PP + +  +  VP  + P +PP 
Sbjct: 842 KQQSFCAKPPPSPLSPVPSVVKQIASQFPP----PPTPPAMESQPLKPVPANVAPQSPPA 897

Query: 639 MAPRP---PPMI-VPTAFVPAPP-----VAPVPAPAPMPPVHPPPPMEDEPTSKK 684
           +  +P   P  I VP+   P PP     V P P P+P+P   PPPP    PT  K
Sbjct: 898 VKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDK 952



 Score = 67.8 bits (164), Expect = 4e-11
 Identities = 48/164 (29%), Positives = 61/164 (37%), Gaps = 23/164 (14%)

Query: 547 PSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAV------------ 594
           P  P   P  PPPP     +PS + P      P  +     T + +A             
Sbjct: 630 PPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTP 689

Query: 595 PVMPRPPMASVVRLPPGSVIAPMPPIIHAP-------RINVVPMPPSAPPIMAPRPPPMI 647
           PVM    +   + +PP  V+ P PP    P       ++   P  PS P   AP PP  I
Sbjct: 690 PVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKI 749

Query: 648 VP----TAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKT 687
                 T   P  P  P P PAP+PP  PP P+   P     KT
Sbjct: 750 HQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKT 793



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 46/146 (31%), Positives = 55/146 (37%), Gaps = 35/146 (23%)

Query: 554 PQQPPPPSSATNIPSSAPPITSVPRP-PTMPPPVRTTVVSAVPVMPRPPMASVVRLP--P 610
           P  PPPP     +P  APP   V  P PT    V   V  A P  P PP+    + P  P
Sbjct: 761 PTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFP 820

Query: 611 GSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPV 670
            S I P PP                PP+  P PP +    +F   PP      P+P+ PV
Sbjct: 821 ASYIPPSPP---------------TPPVPVP-PPTLPKQQSFCAKPP------PSPLSPV 858

Query: 671 ----------HPPPPMEDEPTSKKLK 686
                      PPPP      S+ LK
Sbjct: 859 PSVVKQIASQFPPPPTPPAMESQPLK 884



 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 20/48 (41%), Positives = 27/48 (56%)

Query: 634 SAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPT 681
           S  P ++P+P  +   TA  P+PP+ P P P P PP  PPPP    P+
Sbjct: 604 SLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPS 651



 Score = 39.7 bits (91), Expect = 0.011
 Identities = 19/53 (35%), Positives = 24/53 (45%), Gaps = 6/53 (11%)

Query: 630 PMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPTS 682
           P P    P  A +P P +      P PP  P P P P PP  PP P +  P++
Sbjct: 611 PQPKIVTPYTASQPSPPL------PPPPPPPPPPPPPPPPPPPPLPSQSAPSA 657



 Score = 38.9 bits (89), Expect = 0.019
 Identities = 52/191 (27%), Positives = 69/191 (36%), Gaps = 26/191 (13%)

Query: 537  PEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITS-VPRPPTMPPPVRTTVVSAVP 595
            P       I  S   E P+ P  PS  + +    PP  S  P   T+PPP       A P
Sbjct: 973  PTPQRNSSIKSSSGAEHPE-PKRPSVDSLVSKFTPPAESGSPSKETLPPP-------AAP 1024

Query: 596  VMPRPPMASVVRLP----PGSVIAPMPPIIHAPRINVV--PMPPSAPPIMAPRP------ 643
              P     S V LP     G V A  P +    + +VV  P PPS      P P      
Sbjct: 1025 PKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPL 1084

Query: 644  PPMIVPTAFV--PAPPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMPEEEFLRRN 701
            PP+ +P  F    +P VA V    P P       ++  P   + K  DS    +  +   
Sbjct: 1085 PPIEIPAVFSGNTSPKVAVV---NPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQ 1141

Query: 702  KGPVSIKVQVP 712
                ++  QVP
Sbjct: 1142 PTMATVVPQVP 1152



 Score = 38.5 bits (88), Expect = 0.025
 Identities = 25/73 (34%), Positives = 31/73 (42%), Gaps = 11/73 (15%)

Query: 617 MPPIIHAPRINVVPMPPS--APPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPP 674
           +PP+   P+I V P   S  +PP+  P PPP        P PP  P P P P+P    P 
Sbjct: 606 VPPLSPQPKI-VTPYTASQPSPPLPPPPPPP--------PPPPPPPPPPPPPLPSQSAPS 656

Query: 675 PMEDEPTSKKLKT 687
                P   K  T
Sbjct: 657 AGSAAPMFVKYST 669



 Score = 37.7 bits (86), Expect = 0.042
 Identities = 51/206 (24%), Positives = 66/206 (32%), Gaps = 44/206 (21%)

Query: 547  PSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPP----- 601
            P  P      PPPP S    P   PP T+ P P     P + T  ++ P   +PP     
Sbjct: 918  PPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQR 977

Query: 602  MASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVP------TAFVPA 655
             +S+          P  P + +      P   S  P     PPP   P       + V  
Sbjct: 978  NSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNL 1037

Query: 656  PPV---------APV------------PAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMPE 694
            P V         APV            P+P       PPPP  + P           +P 
Sbjct: 1038 PGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELP-----------LPP 1086

Query: 695  EEFLRRNKGPVSIKVQVPNMQDKTEW 720
             E      G  S KV V N Q + +W
Sbjct: 1087 IEIPAVFSGNTSPKVAVVNPQPQ-QW 1111



 Score = 35.8 bits (81), Expect = 0.16
 Identities = 37/141 (26%), Positives = 49/141 (34%), Gaps = 27/141 (19%)

Query: 295 FPPPTTPEELGARILIQERYEKFGESEEVEMEVESDEEDDKQEKAEEPPSQLDQDTQVQD 354
           FPPP TP  + ++ L           + V   V        + K +  PS +     V  
Sbjct: 869 FPPPPTPPAMESQPL-----------KPVPANVAPQSPPAVKAKPKWQPSSIP----VPS 913

Query: 355 MDEGSDDEEEGQKVPPPPETPMPPPLP-------PTPDQVIVRKDYDPKASKPLPPAPAP 407
            D      E     PPPP +P+P P P       PTPD+         K S P    P P
Sbjct: 914 PDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPP 973

Query: 408 DEYLVSPITGEKIPASKMQEH 428
                +P     I +S   EH
Sbjct: 974 -----TPQRNSSIKSSSGAEH 989



 Score = 35.0 bits (79), Expect = 0.27
 Identities = 44/171 (25%), Positives = 65/171 (38%), Gaps = 18/171 (10%)

Query: 2    PAGPVQAVPPPPPVPTEPKQPTEEEASS--KEDSAPSKPVVGIIYPPPEVRNIVDKTASF 59
            P  P   VP PPP P     PT +++ S  K+ S  S P  G   PP   RN   K++S 
Sbjct: 928  PPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSP-GGKKPPPTPQRNSSIKSSSG 986

Query: 60   VARNGPEFEARIRQNEINNPKFNFLNP---NDPYHAYYRHKVSEFKEGKAQEPSAAIPKV 116
                 P      ++  +++    F  P     P         +  K GK       +P V
Sbjct: 987  AEHPEP------KRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGV 1040

Query: 117  MQQQQQTTQQQ-LPQKVQAQVIQETIVPKE-----PPPEFEFIADPPSISA 161
            +QQ   + +   L  + +  V++    P +     PPPE E    P  I A
Sbjct: 1041 LQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPA 1091



 Score = 33.5 bits (75), Expect = 0.79
 Identities = 17/56 (30%), Positives = 25/56 (44%), Gaps = 10/56 (17%)

Query: 2   PAGPVQAVPPPPPVP----TEPKQPTEEEASSKEDSAPSKPVVGII------YPPP 47
           PA P   +PP PP P      P  P ++   +K   +P  PV  ++      +PPP
Sbjct: 817 PAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPP 872



 Score = 33.1 bits (74), Expect = 1.0
 Identities = 43/158 (27%), Positives = 53/158 (33%), Gaps = 64/158 (40%)

Query: 561 SSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPI 620
           SS   + S   P TS+  P +  P + T   ++ P  P PP              P PP 
Sbjct: 590 SSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPP--------------PPPP- 634

Query: 621 IHAPRINVVPMPPSAPPIMAPRPPPMI----VPTA------FV----------------- 653
                    P PP  PP   P PPP +     P+A      FV                 
Sbjct: 635 ---------PPPPPPPP---PPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGA 682

Query: 654 ----PAPPVAPVPAPAP---MPP---VHPPPPMEDEPT 681
               P PPV    +  P   +PP   V PPPP    PT
Sbjct: 683 LFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPT 720



 Score = 30.8 bits (68), Expect = 5.1
 Identities = 17/42 (40%), Positives = 18/42 (42%), Gaps = 5/42 (11%)

Query: 366 QKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAP 407
           Q  PP P     PP+PP   Q      Y P  S P PP P P
Sbjct: 800 QAAPPTPT----PPVPPAKKQPAFPASYIP-PSPPTPPVPVP 836



 Score = 30.0 bits (66), Expect = 8.8
 Identities = 37/171 (21%), Positives = 54/171 (31%), Gaps = 21/171 (12%)

Query: 1   MPAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAP-------------SKPVVGIIYPPP 47
           +P  P    PPPPP P  P     + A S   +AP             +    G ++ PP
Sbjct: 628 LPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPP 687

Query: 48  EVRNIVDKTASFVARNGPEFEARIRQNEINNPKFNFLNPNDPYHAYYRHKVSEFKEGKAQ 107
                   T   +     + +  +  N +  P      P  P  A  + K +       Q
Sbjct: 688 --------TPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQ 739

Query: 108 EPSAAIPKVMQQQQQTTQQQLPQKVQAQVIQETIVPKEPPPEFEFIADPPS 158
             +   P  + Q Q  TQ   P       I   + P+ PP     I  P S
Sbjct: 740 FSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTS 790



 Score = 30.0 bits (66), Expect = 8.8
 Identities = 36/176 (20%), Positives = 57/176 (32%), Gaps = 43/176 (24%)

Query: 2   PAGPVQAVPPP--------------PPVPTEPKQPTEEE-ASSKEDSAPSKPVVGIIYPP 46
           P  P+  +P P              PP PT P  P +++ A       PS P   +  PP
Sbjct: 778 PPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPP 837

Query: 47  PEVRNIVDKTASFVARNGPEFEARIRQNEINNPKFNFLNPNDPYHAYYRHKVSEF----- 101
           P     + K  SF A+  P                   +P  P  +  +   S+F     
Sbjct: 838 P----TLPKQQSFCAKPPP-------------------SPLSPVPSVVKQIASQFPPPPT 874

Query: 102 KEGKAQEPSAAIPKVMQQQQQTTQQQLPQKVQAQVIQETIVPKEPPPEFEFIADPP 157
                 +P   +P  +  Q     +  P+   + +   +     PPPE   +  PP
Sbjct: 875 PPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPP 930


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 71.2 bits (173), Expect = 3e-12
 Identities = 51/148 (34%), Positives = 59/148 (39%), Gaps = 15/148 (10%)

Query: 547  PSKPNEIPQQPPP---PSSATNIPSSAPPITSVPRPPTM----PPPVRTTVVSAVPVMPR 599
            PS P      PPP   PS  T  PS   P T+ P PPT     PPP  TT  S     P 
Sbjct: 1454 PSPPISTTTTPPPTTTPSPPTTTPS---PPTTTPSPPTTTTTTPPP--TTTPSPPTTTPI 1508

Query: 600  PPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVA 659
             P AS   LPP +  +P       P     P PP+  PI  P     + PT   P+PP  
Sbjct: 1509 TPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTT-TPSPP-- 1565

Query: 660  PVPAPAPMPPVHPPPPMEDEPTSKKLKT 687
            P     P P   P PP    P+   + T
Sbjct: 1566 PTTTTTPPPTTTPSPPTTTTPSPPTITT 1593



 Score = 67.8 bits (164), Expect = 4e-11
 Identities = 46/146 (31%), Positives = 53/146 (36%), Gaps = 19/146 (13%)

Query: 547  PSKPNEIPQQPPP---PSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVP-------- 595
            PS P      PPP   PS  T  P + P  T+   P T P P  TT  +  P        
Sbjct: 1484 PSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPT 1543

Query: 596  VMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPIMAPRPPPMIV-- 648
              P  P  S   LPP +  +P P     P     P P     PS P I    PPP     
Sbjct: 1544 TTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPS 1603

Query: 649  -PTAFVPAPPVAPVPAPAPMPPVHPP 673
             PT     PP    P+P    P+ PP
Sbjct: 1604 PPTTTTTTPPPTTTPSPPTTTPITPP 1629



 Score = 67.0 bits (162), Expect = 6e-11
 Identities = 48/155 (30%), Positives = 61/155 (39%), Gaps = 29/155 (18%)

Query: 547  PSKPNEIPQQPPPPSSATNIPSS---APPITSVPRPP---TMPPPVRTTVVSAVPVMPRP 600
            PS P   P   PPP+S T +P +   +PP T+   PP   T  PP+ TT        P P
Sbjct: 1399 PSPPTTTPS--PPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSP 1456

Query: 601  PMASVVRLPPGSV------------IAPMPPIIHA--PRINVVPMPPSAPPIMAPRPPPM 646
            P+++    PP +               P PP      P     P PP+  PI  P     
Sbjct: 1457 PISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTT 1516

Query: 647  IVPTAFVPAPP----VAPVPAPAPMPPVHPP--PP 675
            + PT   P+PP      P P   P PP   P  PP
Sbjct: 1517 LPPTT-TPSPPTTTTTTPPPTTTPSPPTTTPITPP 1550



 Score = 67.0 bits (162), Expect = 6e-11
 Identities = 40/146 (27%), Positives = 54/146 (36%), Gaps = 9/146 (6%)

Query: 547  PSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPP--PVRTTVVSAVPVMPRPPMAS 604
            PS P   P  P    S     ++ PP T+ P PPT  P  P  +T        P PP  +
Sbjct: 1470 PSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTT 1529

Query: 605  VVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIV---PTAFVPAPPVAPV 661
                PP +  +P       P  +   +PP+      P PPP      P    P+PP    
Sbjct: 1530 TTTPPPTTTPSPPTTTPITPPTSTTTLPPTTT----PSPPPTTTTTPPPTTTPSPPTTTT 1585

Query: 662  PAPAPMPPVHPPPPMEDEPTSKKLKT 687
            P+P  +    PPP     P +    T
Sbjct: 1586 PSPPTITTTTPPPTTTPSPPTTTTTT 1611



 Score = 66.6 bits (161), Expect = 8e-11
 Identities = 48/162 (29%), Positives = 58/162 (35%), Gaps = 19/162 (11%)

Query: 547  PSKPNEIPQQPPP---PSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVP-------- 595
            PS P      PPP   PS  T  P + P  T+   P T P P  TT  +  P        
Sbjct: 1523 PSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPT 1582

Query: 596  -VMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVP 654
               P PP  +    PP +  +P       P     P PP+  PI  P     + PT   P
Sbjct: 1583 TTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTT-TP 1641

Query: 655  APP----VAPVPAPAPMPP--VHPPPPMEDEPTSKKLKTEDS 690
            +PP      P P   P PP    P PP+    T     T  S
Sbjct: 1642 SPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSS 1683



 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 48/169 (28%), Positives = 65/169 (38%), Gaps = 25/169 (14%)

Query: 547  PSKPNEIPQQPP------PPSSATNIP---SSAPPITSVPRPPTMPPPVRTTVVSAVP-- 595
            PS P   P  PP      PP++  + P   ++ PP T+ P PPT   P   T+ +  P  
Sbjct: 1539 PSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPP 1598

Query: 596  -VMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAP----RPPPMIV-- 648
               P PP  +    PP +  +P       P  +   +PP+  P   P     PPP     
Sbjct: 1599 TTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPS 1658

Query: 649  -PTAFVPAPPV----APVPAPAPMPPV--HPPPPMEDEPTSKKLKTEDS 690
             PT   P+PP+     P P   P  P+   P PP     T     T  S
Sbjct: 1659 PPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSS 1707



 Score = 64.3 bits (155), Expect = 4e-10
 Identities = 51/165 (30%), Positives = 64/165 (38%), Gaps = 30/165 (18%)

Query: 547  PSKPNEIPQQPPP------PSSATNIP----SSAPPITSVPRPPTM----PPPVRTTVVS 592
            PS P      PPP      P++ T  P    ++ PP T+ P PPT     PPP  TT  S
Sbjct: 1562 PSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPP--TTTPS 1619

Query: 593  AVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPS----APPIMAPRPPPMIV 648
                 P  P  S   LPP +  +P P     P     P PP+    +PPI     PP   
Sbjct: 1620 PPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPP--- 1676

Query: 649  PTAFVPAPPVAPVPAP------APMPPVHPPPPMEDEPTSKKLKT 687
            PT   P+ P+   P+P       P P   P  P+    T     T
Sbjct: 1677 PTT-TPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTT 1720



 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 45/160 (28%), Positives = 60/160 (37%), Gaps = 27/160 (16%)

Query: 547  PSKPNEIPQQPPPPSSATN--IPSSAPPITSVPRPP----TMPPPVR-----TTVVSAVP 595
            PS P      PPP ++ +     ++ PP T+ P PP    T PPP       TT  S   
Sbjct: 1422 PSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPT 1481

Query: 596  VMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSA------------PPIMAPRP 643
              P PP  +    PP +  +P       P  +   +PP+             PP   P P
Sbjct: 1482 TTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSP 1541

Query: 644  P---PMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEP 680
            P   P+  PT+    PP    P+P P     PPP     P
Sbjct: 1542 PTTTPITPPTSTTTLPPTT-TPSPPPTTTTTPPPTTTPSP 1580



 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 48/161 (29%), Positives = 58/161 (36%), Gaps = 28/161 (17%)

Query: 547  PSKPNEIPQQPPP----------PSSATNIPSSAPPITSVPRPPTMP--PPVRTTVVSAV 594
            PS P   P  PP           PS  T   ++ PP T+   P T P  PP  TT +   
Sbjct: 1500 PSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPT 1559

Query: 595  PVMPRPPMASVVRLP-----PGSVIAPMPPII--HAPRINVVPMPPSA-----PPIMAPR 642
                 PP  +    P     P +   P PP I    P     P PP+      PP   P 
Sbjct: 1560 TTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPS 1619

Query: 643  PP---PMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEP 680
            PP   P+  PT+    PP    P+P P     PPP     P
Sbjct: 1620 PPTTTPITPPTSTTTLPPTT-TPSPPPTTTTTPPPTTTPSP 1659



 Score = 58.2 bits (139), Expect = 3e-08
 Identities = 39/146 (26%), Positives = 54/146 (36%), Gaps = 15/146 (10%)

Query: 547  PSKPNEIPQQPP------PPSSATNIP---SSAPPITSVPRPPTMP---PPVRTTVVSAV 594
            PS P   P  PP      PP++  + P   ++ PP T+ P PPT     PP+ TT     
Sbjct: 1618 PSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPP 1677

Query: 595  PVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVP 654
               P  P+ +    P  ++  P P    +  I     P S      P PPP  + T    
Sbjct: 1678 TTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTT---TPSPPPTTMTTPSPT 1734

Query: 655  APPVAPVPAPAPMPPVHPPPPMEDEP 680
              P  P      +PP     P+   P
Sbjct: 1735 TTPSPPTTTMTTLPPTTTSSPLTTTP 1760



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 40/137 (29%), Positives = 54/137 (39%), Gaps = 16/137 (11%)

Query: 550  PNEIPQQPPPPSSATNIPSS--APPITSVPRPP---TMPPPVRTTVVSAVPVMPRPPMAS 604
            P      PPP ++ T  P++  +PP T+ P PP   T  PP  TT  S +   P PP  +
Sbjct: 1636 PPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTT 1695

Query: 605  VVRLPPGSVIAPMPPIIHA--PRINVVPMPP-----SAPPIMAPRPPPMIVPTAFVPAPP 657
            +    P     P  PI     P     P PP     +  P   P PP   + T  +P   
Sbjct: 1696 MTT--PSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTT--LPPTT 1751

Query: 658  VAPVPAPAPMPPVHPPP 674
             +      P+PP   PP
Sbjct: 1752 TSSPLTTTPLPPSITPP 1768



 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 34/121 (28%), Positives = 45/121 (37%), Gaps = 18/121 (14%)

Query: 566  IPSSAPPITSVPRPPTM----------PPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIA 615
            I + +PP T+   PPT            PP  TT        P PP+ +    PP +  +
Sbjct: 1396 ITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPS 1455

Query: 616  PMPPIIHAPRINVVPMPPS---APPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHP 672
            P       P     P PP+   +PP   P P     PT     PP    P+P    P+ P
Sbjct: 1456 PPISTTTTPPPTTTPSPPTTTPSPPTTTPSP-----PTTTTTTPPPTTTPSPPTTTPITP 1510

Query: 673  P 673
            P
Sbjct: 1511 P 1511



 Score = 53.9 bits (128), Expect = 6e-07
 Identities = 35/129 (27%), Positives = 51/129 (39%), Gaps = 8/129 (6%)

Query: 547  PSKPNEIPQQPPPPSSATNIPSSAP--PITSVPRPPTMP---PPVRTTVVSAVPVMPRPP 601
            PS P      PP  ++ T  P++ P  PIT+ P PPT     P   TT  S +     P 
Sbjct: 1657 PSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPS 1716

Query: 602  MASVVRLPPGSVIAPMPPIIHAP---RINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPV 658
              +    PP ++  P P    +P    +  +P   ++ P+     PP I P  F P    
Sbjct: 1717 STTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTT 1776

Query: 659  APVPAPAPM 667
             P     P+
Sbjct: 1777 TPTTPCVPL 1785



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 45/159 (28%), Positives = 53/159 (33%), Gaps = 20/159 (12%)

Query: 547  PSKPNEIPQQPPP---PSSATNIP-------SSAPPITSVPRPP--TMPPPVRTTVVSAV 594
            PS P      PPP   PS  T  P       ++ PP T+   PP  T  PP  TT     
Sbjct: 1602 PSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPT 1661

Query: 595  PVMPRPPMASVVRLPPGSVIAPMPPIIHAP----RINVVPMPPSAP--PIMAPRPPPMIV 648
               P PP+ +    PP     P  PI   P         P P + P  PI     P    
Sbjct: 1662 TTTPSPPITTTTTPPP--TTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTT 1719

Query: 649  PTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKT 687
              +  P     P P   P PP      +    TS  L T
Sbjct: 1720 TPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTT 1758



 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 36/116 (31%), Positives = 43/116 (37%), Gaps = 16/116 (13%)

Query: 575  SVPRPPTM---PPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPM 631
            + P PPT    PPP  TT +      P PP  +    PP +  +P       P     P 
Sbjct: 1397 TTPSPPTTTPSPPPTSTTTLPPTTT-PSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPS 1455

Query: 632  PP-----SAPPIMAPRPPPMI-VPTAFVPAPP----VAPVPAPAPMPPVHPP--PP 675
            PP     + PP   P PP     P    P+PP      P P   P PP   P  PP
Sbjct: 1456 PPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPP 1511



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 43/145 (29%), Positives = 51/145 (35%), Gaps = 20/145 (13%)

Query: 547  PSKPNEIPQQPPP---PSSATNIPSSAPPITSVPRPP----------TMPPPVRTTVVSA 593
            PS P      PPP   PS  T    S PPIT+   PP          T P P  TT+ + 
Sbjct: 1641 PSPPPTTTTTPPPTTTPSPPTTTTPS-PPITTTTTPPPTTTPSSPITTTPSPPTTTMTTP 1699

Query: 594  VP-VMPRPPMASVVRLPPGSVIAPMPP--IIHAPRINVVPMPPSAPPIMAPRPPPMIVPT 650
             P   P  P+ +     P S   P PP   +  P     P PP+      P P     P 
Sbjct: 1700 SPTTTPSSPITTTT--TPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLP-PTTTSSPL 1756

Query: 651  AFVPAPPVAPVPAPAPMPPVHPPPP 675
               P PP    P  +P     P  P
Sbjct: 1757 TTTPLPPSITPPTFSPFSTTTPTTP 1781



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 35/116 (30%), Positives = 40/116 (34%), Gaps = 17/116 (14%)

Query: 581  TMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPP-----SA 635
            T P P  TT        P PP  S   LPP +  +P       P     P PP     + 
Sbjct: 1397 TTPSPPTTT--------PSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTP 1448

Query: 636  PPIMAPRPPPMIVPTAFVPAPPVAP-VPAPAPMPPVHPPPPMEDEPTSKKLKTEDS 690
            PP   P PP   + T   P P   P  P   P PP   P P     T+    T  S
Sbjct: 1449 PPTTTPSPP---ISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPS 1501



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 34/139 (24%), Positives = 45/139 (32%), Gaps = 18/139 (12%)

Query: 557  PPPPSSATNIPSSAPPITSVPRPPTMPP-----PVRTTVVSAVPVMPRPPMASVVRLPPG 611
            P P  + T  P++ P  T+    PT  P     P  T + +   V P P        P G
Sbjct: 4094 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-------PTG 4146

Query: 612  SVIAPMPPIIHAPRINVVPMP-----PSAPPIMAPRP-PPMIVPTAFVPAPPVAPVPAPA 665
            +      PI     +   P P     P+  PI       P   PT     PP     AP 
Sbjct: 4147 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPI 4206

Query: 666  PMPPVHPPPPMEDEPTSKK 684
                   PPP    P + +
Sbjct: 4207 AELTTSNPPPESSTPQTSR 4225



 Score = 39.7 bits (91), Expect = 0.011
 Identities = 26/95 (27%), Positives = 33/95 (34%), Gaps = 14/95 (14%)

Query: 601  PMASVVRLPPGSVIAPMPPIIHAPRI--NVVPMPPSA-----PPIMAPRPP---PMIVPT 650
            PM   +  P      P PP      +     P PP+      PP   P PP       P 
Sbjct: 1391 PMDKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPP 1450

Query: 651  AFVPAPPVA----PVPAPAPMPPVHPPPPMEDEPT 681
               P+PP++    P P   P PP   P P    P+
Sbjct: 1451 TTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPS 1485



 Score = 38.1 bits (87), Expect = 0.032
 Identities = 31/116 (26%), Positives = 40/116 (34%), Gaps = 23/116 (19%)

Query: 537  PEDDTKEKIGPSKPNEIPQQPPPPS---SATNIPSSAPPITSVPRPPTMPPPVRTTVVSA 593
            P   T     PS P   P  P   +   S+T  PS  P   + P P T P P  TT+ + 
Sbjct: 1689 PSPPTTTMTTPS-PTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTL 1747

Query: 594  VPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVP 649
             P     P+ +           P+PP I          PP+  P     P    VP
Sbjct: 1748 PPTTTSSPLTT----------TPLPPSI---------TPPTFSPFSTTTPTTPCVP 1784



 Score = 38.1 bits (87), Expect = 0.032
 Identities = 78/364 (21%), Positives = 111/364 (30%), Gaps = 86/364 (23%)

Query: 369  PPPPETPMPPP-----LPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPAS 423
            P P  TP PP      LPPT           P  + PLPP+  P  +     T    P  
Sbjct: 1731 PSPTTTPSPPTTTMTTLPPTTTS-------SPLTTTPLPPSITPPTFSPFSTTTPTTPCV 1783

Query: 424  KMQEHMRIGLLDPRWLEQRDRSIREKQSDDE----VYAPGLDIESSLKQLAERRTDIFGV 479
             +            WL+    +  +   D E    V  PG     S +        I  +
Sbjct: 1784 PLCNWTG-------WLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPDVPIGQL 1836

Query: 480  EETAIGKK----IGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKAKGL 535
             +T +       I + E QKP          G +          I +Q   E + +   +
Sbjct: 1837 GQTVVCDVSVGLICKNEDQKP----------GGVIPMAFCLNYEINVQ-CCECVTQPTTM 1885

Query: 536  VPEDDTKEKIGPSKPNEIP------QQPPPPSSATNIPSSAP-----PITSVPRP----- 579
                 T     P+ P   P        P P  + T  P++ P      +T  P P     
Sbjct: 1886 T----TTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 1941

Query: 580  PTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMP-----PS 634
            PT  P   TT V+  P             P G+      PI     +   P P     P+
Sbjct: 1942 PTTTPITTTTTVTPTPT------------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 1989

Query: 635  APPI-----MAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTED 689
              PI     + P P P    T     P   P+     + P  P P     PT+  + T  
Sbjct: 1990 TTPITTTTTVTPTPTPTGTQT-----PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTT 2043

Query: 690  SLMP 693
            ++ P
Sbjct: 2044 TVTP 2047



 Score = 38.1 bits (87), Expect = 0.032
 Identities = 37/155 (23%), Positives = 51/155 (32%), Gaps = 28/155 (18%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P        +  
Sbjct: 4071 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 4130

Query: 607  RLPPGSVIAPMP-----------PIIHAPRINVVPMP-----PSAPPIMAPRP-PPMIVP 649
             +   + + P P           PI     +   P P     P+  PI       P   P
Sbjct: 4131 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 4190

Query: 650  TAFVPAPPVAPVPAP-APMPPVHPPPPMEDEPTSK 683
            T     PP     AP A +   +PPP      TS+
Sbjct: 4191 TGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSR 4225



 Score = 37.0 bits (84), Expect = 0.072
 Identities = 39/179 (21%), Positives = 57/179 (31%), Gaps = 37/179 (20%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P        +  
Sbjct: 4025 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 4084

Query: 607  RLPPGSVIAPMP-----------PIIHAPRINVVPMP-----PSAPPI-----MAPRPPP 645
             +   + + P P           PI     +   P P     P+  PI     + P P P
Sbjct: 4085 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 4144

Query: 646  MIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMPEEEFLRRNKGP 704
                T     P   P+     + P  P P     PT+  + T  ++ P         GP
Sbjct: 4145 TGTQT-----PTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGP 4197



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 1932 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 1981

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 1982 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2034

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 2035 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2070



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 1955 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2004

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 2005 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2057

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 2058 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2093



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 1978 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2027

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 2028 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2080

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 2081 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2116



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 2001 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2050

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 2051 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2103

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 2104 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2139



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 2024 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2073

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 2074 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2126

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 2127 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2162



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 2047 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2096

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 2097 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2149

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 2150 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2185



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 2070 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2119

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 2120 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2172

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 2173 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2208



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 2093 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2142

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 2143 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2195

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 2196 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2231



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 2116 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2165

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 2166 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2218

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 2219 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2254



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 2139 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2188

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 2189 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2241

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 2242 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2277



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 2162 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2211

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 2212 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2264

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 2265 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2300



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 2185 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2234

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 2235 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2287

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 2288 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2323



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 2208 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2257

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 2258 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2310

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 2311 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2346



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 2231 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2280

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 2281 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2333

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 2334 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2369



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 2254 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2303

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 2304 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2356

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 2357 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2392



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 2277 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2326

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 2327 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2379

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 2380 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2415



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 2300 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2349

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 2350 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2402

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 2403 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2438



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 2323 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2372

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 2373 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2425

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 2426 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2461



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 2346 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2395

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 2396 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2448

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 2449 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2484



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 2369 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2418

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 2419 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2471

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 2472 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2507



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 2392 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2441

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 2442 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2494

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 2495 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2530



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 2415 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2464

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 2465 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2517

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 2518 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2553



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 2438 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2487

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 2488 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2540

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 2541 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2576



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 2461 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2510

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 2511 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2563

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 2564 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2599



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 2484 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2533

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 2534 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2586

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 2587 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2622



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 2507 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2556

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 2557 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2609

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 2610 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2645



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 2530 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2579

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 2580 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2632

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 2633 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2668



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 2553 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2602

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 2603 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2655

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 2656 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2691



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 2576 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2625

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 2626 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2678

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 2679 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2714



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 2599 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2648

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 2649 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2701

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 2702 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2737



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 2622 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2671

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 2672 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2724

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 2725 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2760



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 2645 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2694

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 2695 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2747

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 2748 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2783



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 2668 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2717

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 2718 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2770

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 2771 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2806



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 2691 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2740

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 2741 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2793

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 2794 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2829



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 2714 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2763

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 2764 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2816

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 2817 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2852



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 2737 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2786

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 2787 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2839

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 2840 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2875



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 2760 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2809

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 2810 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2862

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 2863 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2898



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 2783 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2832

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 2833 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2885

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 2886 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2921



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 2806 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2855

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 2856 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2908

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 2909 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2944



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 2829 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2878

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 2879 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2931

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 2932 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2967



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 2852 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2901

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 2902 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2954

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 2955 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 2990



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 2875 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2924

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 2925 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 2977

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 2978 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3013



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 2898 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2947

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 2948 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3000

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 3001 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3036



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 2921 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2970

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 2971 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3023

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 3024 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3059



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 2944 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 2993

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 2994 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3046

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 3047 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3082



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 2967 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3016

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 3017 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3069

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 3070 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3105



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 2990 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3039

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 3040 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3092

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 3093 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3128



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 3013 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3062

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 3063 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3115

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 3116 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3151



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 3036 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3085

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 3086 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3138

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 3139 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3174



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 3059 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3108

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 3109 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3161

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 3162 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3197



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 3082 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3131

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 3132 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3184

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 3185 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3220



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 3105 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3154

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 3155 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3207

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 3208 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3243



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 3128 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3177

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 3178 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3230

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 3231 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3266



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 3151 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3200

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 3201 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3253

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 3254 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3289



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 3174 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3223

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 3224 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3276

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 3277 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3312



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 3197 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3246

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 3247 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3299

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 3300 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3335



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 3220 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3269

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 3270 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3322

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 3323 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3358



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 3243 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3292

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 3293 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3345

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 3346 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3381



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 3266 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3315

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 3316 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3368

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 3369 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3404



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 3289 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3338

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 3339 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3391

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 3392 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3427



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 3312 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3361

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 3362 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3414

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 3415 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3450



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 3335 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3384

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 3385 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3437

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 3438 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3473



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 3358 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3407

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 3408 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3460

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 3461 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3496



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 3381 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3430

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 3431 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3483

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 3484 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3519



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 3404 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3453

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 3454 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3506

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 3507 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3542



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 3427 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3476

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 3477 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3529

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 3530 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3565



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 3450 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3499

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 3500 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3552

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 3553 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3588



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 3473 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3522

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 3523 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3575

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 3576 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3611



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 3496 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3545

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 3546 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3598

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 3599 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3634



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 3519 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3568

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 3569 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3621

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 3622 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3657



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 3542 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3591

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 3592 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3644

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 3645 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3680



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 3565 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3614

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 3615 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3667

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 3668 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3703



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 3588 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3637

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 3638 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3690

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 3691 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3726



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 3611 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3660

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 3661 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3713

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 3714 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3749



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 3634 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3683

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 3684 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3736

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 3737 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3772



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 3657 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3706

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 3707 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3759

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 3760 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3795



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 3680 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3729

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 3730 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3782

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 3783 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3818



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 3703 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3752

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 3753 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3805

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 3806 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3841



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 3726 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3775

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 3776 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3828

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 3829 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3864



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 3749 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3798

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 3799 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3851

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 3852 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3887



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 3772 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3821

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 3822 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3874

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 3875 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3910



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 3795 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3844

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 3845 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3897

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 3898 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3933



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 3818 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3867

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 3868 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3920

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 3921 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3956



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 3841 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3890

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 3891 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3943

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 3944 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 3979



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 3864 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3913

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 3914 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3966

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 3967 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 4002



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 3887 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3936

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 3937 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 3989

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 3990 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 4025



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 3910 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3959

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 3960 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 4012

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 4013 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 4048



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 3933 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 3982

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 3983 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 4035

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 4036 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 4071



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 3956 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 4005

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 4006 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 4058

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 4059 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 4094



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 3979 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 4028

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 4029 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 4081

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 4082 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 4117



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 37/157 (23%), Positives = 52/157 (33%), Gaps = 38/157 (24%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P           
Sbjct: 4002 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------- 4051

Query: 607  RLPPGSVIAPMPPIIHAPRINVVPMP-----PSAPPI-----MAPRPPPMIVPTAFVPAP 656
              P G+      PI     +   P P     P+  PI     + P P P    T     P
Sbjct: 4052 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----P 4104

Query: 657  PVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
               P+     + P  P P     PT+  + T  ++ P
Sbjct: 4105 TTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTP 4140



 Score = 33.1 bits (74), Expect = 1.0
 Identities = 33/144 (22%), Positives = 52/144 (36%), Gaps = 31/144 (21%)

Query: 557  PPPPSSATNIPSSAP-----PITSVPRP-----PTMPPPVRTTVVSAVPVMPRPPMASVV 606
            P P  + T  P++ P      +T  P P     PT  P   TT V+  P     P  +  
Sbjct: 4140 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT----PTGTQT 4195

Query: 607  RLPPGSVIAPM--------PPIIHAPRINVVPMPP--SAPPIMAPRPPPMIVPTAFVPAP 656
              P  +  AP+        PP    P+ +     P   +  +++  PP + + +   P+ 
Sbjct: 4196 GPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPST 4255

Query: 657  PVAPVP-------APAPMPPVHPP 673
            P AP         +P P     PP
Sbjct: 4256 PTAPTTTSGGHTLSPPPSTTTSPP 4279



 Score = 31.2 bits (69), Expect = 3.9
 Identities = 16/52 (30%), Positives = 20/52 (38%), Gaps = 6/52 (11%)

Query: 2    PAGPVQAVPPPP------PVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPP 47
            P+ P     PPP      P  T P  PT    +    + PS P+     PPP
Sbjct: 1399 PSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPP 1450



 Score = 31.2 bits (69), Expect = 3.9
 Identities = 17/44 (38%), Positives = 18/44 (40%), Gaps = 5/44 (11%)

Query: 369  PPPPETPMPP---PLPP--TPDQVIVRKDYDPKASKPLPPAPAP 407
            PPP  TP PP   P PP  TP          P  + P PP   P
Sbjct: 1464 PPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTP 1507



 Score = 31.2 bits (69), Expect = 3.9
 Identities = 14/43 (32%), Positives = 16/43 (37%)

Query: 5    PVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPP 47
            P     P PP  T P  PT    +    + PS P      PPP
Sbjct: 1572 PPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPP 1614



 Score = 30.8 bits (68), Expect = 5.1
 Identities = 34/133 (25%), Positives = 48/133 (36%), Gaps = 22/133 (16%)

Query: 557  PPPPSSA--TNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVI 614
            PPP SS   T+  +S+P   S     T+PP +  T  +A P  P  P  +      G  +
Sbjct: 4214 PPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS-TAPPSTPTAPTTT----SGGHTL 4268

Query: 615  APMPPIIHAPRINVVPMPPSAPPI-----MAPRPPPMIVPTAFVPAPPVAPVPAPAPMPP 669
            +P P        +    PP  P        +  P P  V T    A    P P P   P 
Sbjct: 4269 SPPP--------STTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSA--WTPTPTPLSTPS 4318

Query: 670  VHPPPPMEDEPTS 682
            +     +   P+S
Sbjct: 4319 IIRTTGLRPYPSS 4331



 Score = 30.4 bits (67), Expect = 6.7
 Identities = 17/53 (32%), Positives = 19/53 (35%), Gaps = 7/53 (13%)

Query: 369  PPPPETPMPP-------PLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSP 414
            PPP  TP PP       P   TP   I      P  + P PP   P     +P
Sbjct: 1432 PPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTP 1484



 Score = 30.0 bits (66), Expect = 8.8
 Identities = 23/67 (34%), Positives = 26/67 (38%), Gaps = 12/67 (17%)

Query: 369  PPPPETPMPP----PLPP---TPDQVIVRKDYDPKASKPLPP-----APAPDEYLVSPIT 416
            PPP  TP PP    P PP   T           P  + P PP      P+P     SPIT
Sbjct: 1651 PPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPIT 1710

Query: 417  GEKIPAS 423
                P+S
Sbjct: 1711 TTTTPSS 1717


>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
           sapiens]
          Length = 483

 Score = 70.5 bits (171), Expect = 6e-12
 Identities = 84/343 (24%), Positives = 121/343 (35%), Gaps = 54/343 (15%)

Query: 368 VPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPIT-----GEKIPA 422
           VPPPP  P+PPP PP              A  P PP+  P     S +      G     
Sbjct: 3   VPPPPPPPLPPPPPPLG------------APPPPPPSAPPVSTDTSSLRRADPKGRSALL 50

Query: 423 SKMQEHMR---IGLLDPRWLEQRDRSI-REKQSDDEVYAPGLDIESSLKQLAERRTDIF- 477
           + +Q+  R   +  ++ R   Q + S    K+        G     +L  L      +  
Sbjct: 51  ADIQQGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLR 110

Query: 478 --GVEETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKAKGL 535
             G  + A GK       + P  ++     SG +         N +     EA   A+  
Sbjct: 111 PAGQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTS-----EAHGAARTA 165

Query: 536 VPEDDTKEKIGPSKPNEIPQQPPP-PSSAT---------------NIPSSAPPITSVPRP 579
            P  +      P+ P   P  PPP PSS+                N+P  APP+   P P
Sbjct: 166 PPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPP 225

Query: 580 PTMPPPVRTTVVSAVPVMPRP---PMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAP 636
           P  PPP     +    V+      P  + + LPP     P+ P    P +   P  P+  
Sbjct: 226 PPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQD 285

Query: 637 PIMAPRPPPMI------VPTAFVPAPPVAPVPAPAPMPPVHPP 673
               P PPP +       P A +PAPP+  V + +  PP  PP
Sbjct: 286 AQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPP 328



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 44/168 (26%), Positives = 59/168 (35%), Gaps = 36/168 (21%)

Query: 547 PSKPNEIPQQPP-PPSSATNIPSSAPPITSVPRPPTMPP------------------PVR 587
           P  P   P  PP PP+S  +  +  P +  +  PP  PP                  P +
Sbjct: 225 PPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQ 284

Query: 588 TTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMI 647
                  P  P PP AS    P  S+ AP  P +++      P+PP +P   AP   P  
Sbjct: 285 DAQEPPAPPPPLPPYASCS--PRASLPAPPLPGVNSSSETPPPLPPKSPSFQAP---PQK 339

Query: 648 VPTAFVPAPPVAPVPAPAPMPPVH------------PPPPMEDEPTSK 683
                +PAPP  P   P      H            PP P    PT++
Sbjct: 340 AGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSPTTE 387



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 47/201 (23%), Positives = 65/201 (32%), Gaps = 71/201 (35%)

Query: 553 IPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGS 612
           +P  PPPP     +P   PP+ + P PP   PPV T   S     P+   A +  +  G+
Sbjct: 3   VPPPPPPP-----LPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGT 57

Query: 613 VIAPMPPIIH--APRINV----------------VPMPPSAPPIMA-------------- 640
            +  +  I    AP+I                     PP+   + A              
Sbjct: 58  RLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDV 117

Query: 641 ---------------PRPPPMIVPTAFVP------------------APPVAPVPAPAPM 667
                          PR P   +    +P                  APP   VPAP P 
Sbjct: 118 AGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPP 177

Query: 668 PPVHPPPPMEDE-PTSKKLKT 687
            P  PPPP+    P+S  +KT
Sbjct: 178 TPPPPPPPLPPPLPSSSPIKT 198



 Score = 35.0 bits (79), Expect = 0.27
 Identities = 19/45 (42%), Positives = 22/45 (48%), Gaps = 1/45 (2%)

Query: 3   AGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPP 47
           A PV   PPPPP P  P  P    AS   D A  KP +  ++ PP
Sbjct: 216 APPVPCAPPPPPPPPPPTPPPLPPASVLSDKA-VKPQLAPLHLPP 259



 Score = 34.7 bits (78), Expect = 0.36
 Identities = 15/32 (46%), Positives = 19/32 (59%), Gaps = 3/32 (9%)

Query: 629 VPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAP 660
           +P+PP  PP + P PPP+  P    P PP AP
Sbjct: 1   MPVPPPPPPPLPPPPPPLGAPP---PPPPSAP 29



 Score = 34.3 bits (77), Expect = 0.46
 Identities = 15/38 (39%), Positives = 21/38 (55%), Gaps = 2/38 (5%)

Query: 653 VPAPPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDS 690
           +P PP  P P P P PP+  PPP    P++  + T+ S
Sbjct: 1   MPVPPPPPPPLPPPPPPLGAPPP--PPPSAPPVSTDTS 36



 Score = 32.0 bits (71), Expect = 2.3
 Identities = 17/44 (38%), Positives = 21/44 (47%), Gaps = 10/44 (22%)

Query: 641 PRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPP--PPMEDEPTS 682
           P PPP        P PP+ P P P   PP  PP  PP+  + +S
Sbjct: 2   PVPPP--------PPPPLPPPPPPLGAPPPPPPSAPPVSTDTSS 37



 Score = 32.0 bits (71), Expect = 2.3
 Identities = 19/67 (28%), Positives = 25/67 (37%), Gaps = 10/67 (14%)

Query: 358 GSDDEEEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITG 417
           G+  E  G     PP   +P P PPTP          P    PLPP       + +P+  
Sbjct: 153 GNTSEAHGAARTAPPRPNVPAPPPPTP----------PPPPPPLPPPLPSSSPIKTPLVS 202

Query: 418 EKIPASK 424
              P +K
Sbjct: 203 PPGPLTK 209


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 70.1 bits (170), Expect = 8e-12
 Identities = 48/164 (29%), Positives = 67/164 (40%), Gaps = 7/164 (4%)

Query: 536  VPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSA-PPITSVPRPPTMPPPVRTTVVSAV 594
            +P   + E+   +K  ++ +      SA + P  A P  TS P  P + P      V   
Sbjct: 1377 LPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAP---AAAVPGP 1433

Query: 595  PVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPI---MAPRPPPMIVPTA 651
            P +P  P A+    P   ++   PP    P     P PP  PP      P PPP++ PT 
Sbjct: 1434 PPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTP 1493

Query: 652  FVPAPPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMPEE 695
              P PP  P P P  MP   PPPP    P +   +   +  PE+
Sbjct: 1494 SSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPED 1537



 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 56/175 (32%), Positives = 69/175 (39%), Gaps = 28/175 (16%)

Query: 513  QQAAQANITLQEQIEAIHKAKGLVPEDDTKEKIGPSKPN-----EIPQQPPPPS--SATN 565
            + +   N  LQE I +   A    P    K+   P  P       +P  PP P   SA +
Sbjct: 1385 EDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANS 1444

Query: 566  IPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPR 625
              +  PP+     PPT PPP  T      P  P PP       PP     P PP +    
Sbjct: 1445 NGTPEPPLLEEKPPPT-PPPAPTPQ----PQPPPPP-------PPPQPALPSPPPL---- 1488

Query: 626  INVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEP 680
              V P P S PP   P PPP  +P+   P PP  P  AP   PP  P  P  ++P
Sbjct: 1489 --VAPTPSSPPPPPLPPPPPPAMPS---PPPPPPPAAAPLAAPPEEPAAPSPEDP 1538



 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 22/57 (38%), Positives = 30/57 (52%), Gaps = 3/57 (5%)

Query: 365  GQKVPPPPETPMPPPLPPTPDQVIVRK--DYDPKASKPLPPAPAPDEYLVSPITGEK 419
            G    PPP+ P PPP P TP++    K  +  P+ + P PPAP     L+ P+  EK
Sbjct: 1687 GGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKPS-LLRPVEKEK 1742



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 54/253 (21%), Positives = 88/253 (34%), Gaps = 18/253 (7%)

Query: 368  VPPPPETPMPPPLPPTPDQVIVRKDYDPK-ASKPL------PPAPAPDEYLVSPITGEKI 420
            V P P +P PPPLPP P   +      P  A+ PL      P AP+P++  + P T    
Sbjct: 1489 VAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPEL-PDTRPLH 1547

Query: 421  PASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGVE 480
             A K +     G  D    E     I  ++ +  + A  +       Q       I+ V+
Sbjct: 1548 LAKKQETAAVCGETDEEAGESGGEGIFRERDEFVIRAEDIPSLKLALQTGREPPPIWRVQ 1607

Query: 481  ETAIGK-----KIGEEEIQKPEEKVTWDGHSGSM-ARTQQAAQANITLQEQIEAIHKAKG 534
            +  + K     K G+ +       + + G + +   R       N+  ++ +    +   
Sbjct: 1608 KALLQKFTPEIKDGQRQFCATSNYLGYFGDAKNRYQRLYVKFLENVNKKDYVRVCARKPW 1667

Query: 535  LVPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAV 594
              P    +       P        PP  A     + PP    P   T   P   T  +A+
Sbjct: 1668 HRPPVPVRRSGQAKNPVSAGGSSAPPPKAP----APPPKPETPEKTTSEKPPEQTPETAM 1723

Query: 595  PVMPRPPMASVVR 607
            P  P P   S++R
Sbjct: 1724 PEPPAPEKPSLLR 1736



 Score = 38.9 bits (89), Expect = 0.019
 Identities = 25/86 (29%), Positives = 35/86 (40%), Gaps = 29/86 (33%)

Query: 637 PIMAPRPPPMIVPTAFVPAPPVAPVP---------------APAPMPPVHPPPP------ 675
           P++ P PPP ++P+    AP  +P                 AP P PP  PPPP      
Sbjct: 791 PLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQL 850

Query: 676 --------MEDEPTSKKLKTEDSLMP 693
                   +E    S +L+ E+SL P
Sbjct: 851 EAHLRSHGLEPAAPSPRLRPEESLDP 876



 Score = 35.8 bits (81), Expect = 0.16
 Identities = 29/99 (29%), Positives = 34/99 (34%), Gaps = 9/99 (9%)

Query: 315  EKFGESEEVEMEVESDEED------DKQEKAEEPPSQLDQDTQVQDMDEGSDDEEEGQKV 368
            E+   + E      SDEED      D QE      S LD        D  + D   G  +
Sbjct: 1368 EELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPD---GPPL 1424

Query: 369  PPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAP 407
             P    P PPPLP  P          P   +  PP P P
Sbjct: 1425 APAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPP 1463



 Score = 35.4 bits (80), Expect = 0.21
 Identities = 66/303 (21%), Positives = 98/303 (32%), Gaps = 72/303 (23%)

Query: 364  EGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKP-LPPAPAPDEYLVSPITGEKIPA 422
            +G   PPPP  P PPP+P   +  +     +P A  P L P  + D            P 
Sbjct: 830  DGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLD------------PP 877

Query: 423  SKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGVEET 482
              MQE   +G L+P      D  +    S+ +  A      S     A R   +  +   
Sbjct: 878  GAMQE--LLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSI--- 932

Query: 483  AIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQI---EAIHKAKGLVPED 539
                    + + + EE+  +                  T++E      A    K   PED
Sbjct: 933  -----CFPDSLLQDEERSFFP-----------------TMEEMFGGGAADDYGKAGPPED 970

Query: 540  DTKEKIG----PSKPNEIPQQPPPPSSATNIPSSAPPITSVP-RPPTMPPPVRTTVVSAV 594
            +   K G    P  P   P  P  P  A+      P +   P +PP +P     + V+A 
Sbjct: 971  EGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELP-----STVNAE 1025

Query: 595  PVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVP 654
            P+        +++  P     P PP            PP  PP  A  P   +    F  
Sbjct: 1026 PL-------GLIQSGPHQAAPPPPP------------PPPPPPAPASEPKGGLTSPIFCS 1066

Query: 655  APP 657
              P
Sbjct: 1067 TKP 1069



 Score = 35.4 bits (80), Expect = 0.21
 Identities = 21/54 (38%), Positives = 23/54 (42%), Gaps = 8/54 (14%)

Query: 362  EEEGQKVPPPPETPMP-PPLPPTPDQ-------VIVRKDYDPKASKPLPPAPAP 407
            EE+    PPP  TP P PP PP P Q        +V          PLPP P P
Sbjct: 1454 EEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPP 1507



 Score = 34.7 bits (78), Expect = 0.36
 Identities = 25/85 (29%), Positives = 30/85 (35%)

Query: 366  QKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKM 425
            Q  PPPP  P  P LP  P  V       P    P PP PA       P       A+  
Sbjct: 1468 QPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPP 1527

Query: 426  QEHMRIGLLDPRWLEQRDRSIREKQ 450
            +E       DP   + R   + +KQ
Sbjct: 1528 EEPAAPSPEDPELPDTRPLHLAKKQ 1552



 Score = 33.9 bits (76), Expect = 0.61
 Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 12/68 (17%)

Query: 3    AGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPPEVRNIVDKTASF--V 60
            +GP QA PPPPP P  P  P  E         P   +   I+   + + ++ KT+SF  +
Sbjct: 1032 SGPHQAAPPPPPPPPPPPAPASE---------PKGGLTSPIFCSTKPKKLL-KTSSFHLL 1081

Query: 61   ARNGPEFE 68
             R  P F+
Sbjct: 1082 RRRDPPFQ 1089



 Score = 33.5 bits (75), Expect = 0.79
 Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 4/46 (8%)

Query: 2    PAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPP 47
            PA   Q  PPPPP P +P  P+     +   S+P  P +    PPP
Sbjct: 1463 PAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPL----PPP 1504



 Score = 32.0 bits (71), Expect = 2.3
 Identities = 36/134 (26%), Positives = 50/134 (37%), Gaps = 27/134 (20%)

Query: 560 PSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMP-RPPMASVV-------RLPPG 611
           P+S  + P   P   S+  PP  PP     ++S   V+  +P  A  V       RL  G
Sbjct: 154 PASFGSRPFPVPSSLSLQDPPFSPPA--NGLLSPHDVLHLKPSQAPTVPSSLGFERLAGG 211

Query: 612 SVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAF--VPAPPVAPVPAPAPMPP 669
            V+ P         +     PP  P    P PPP  +PT F  + +   A   A    P 
Sbjct: 212 GVLGPAG-------LGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQ 264

Query: 670 VH--------PPPP 675
           ++        PPPP
Sbjct: 265 LYNFSGAAPGPPPP 278



 Score = 30.4 bits (67), Expect = 6.7
 Identities = 25/90 (27%), Positives = 32/90 (35%), Gaps = 17/90 (18%)

Query: 567 PSSAPPITSVPRPPTMPPPVR-----------TTVVSAVPVMPRPPMASVVRLPPGSVIA 615
           P+  PP    P PP  PPP R           ++  +A      P + +     PG    
Sbjct: 221 PAQTPPYR--PGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPG---- 274

Query: 616 PMPPIIHAPRINVVPMPPSAPPIMAPRPPP 645
           P PP    PR + V      P    P PPP
Sbjct: 275 PPPPERALPRQDTVIKHYQRPASAQPPPPP 304


>gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 50/157 (31%), Positives = 67/157 (42%), Gaps = 12/157 (7%)

Query: 529 IHKAKGLVPEDDTKEKIGPSKPNEIPQQPPPPS---SATNIPSSAPPITSVPRPPTMPPP 585
           I  A GL+         G +     P  PPPP    SA +  S    +TS P PP  PPP
Sbjct: 297 ISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPP 356

Query: 586 VRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPP 645
                    P +P PP  + +++ PG V+ P PP I AP     P+   +PP+    P  
Sbjct: 357 PPPATALQAPAVPPPP--APLQIAPG-VLHPAPPPI-AP-----PLVQPSPPVARAAPVC 407

Query: 646 MIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPTS 682
             VP   +P   V  +P P P PP+ PP      P +
Sbjct: 408 ETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVT 444



 Score = 63.9 bits (154), Expect = 5e-10
 Identities = 48/146 (32%), Positives = 57/146 (39%), Gaps = 23/146 (15%)

Query: 554 PQQPPPP------SSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPP------ 601
           P +PPPP        A  IP+     T +       P    T V   P  P PP      
Sbjct: 275 PHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSA 334

Query: 602 ------MASVVRLPPGSVIAPMPPIIHAPRINVVPMPPS----APPIMAPRPPPMIVPTA 651
                  AS+   PP  V  P PP   A +   VP PP+    AP ++ P PPP I P  
Sbjct: 335 LSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPP-IAPPL 393

Query: 652 FVPAPPVAPVPAPAPMPPVHPPPPME 677
             P+PPVA         PVHP P  E
Sbjct: 394 VQPSPPVARAAPVCETVPVHPLPQGE 419



 Score = 56.6 bits (135), Expect = 9e-08
 Identities = 50/161 (31%), Positives = 64/161 (39%), Gaps = 34/161 (21%)

Query: 550 PNEIPQQPPPPSSATNIPSSAPPITSV--------PRPPTMPPPV---------RTTVVS 592
           P  +P  PPPP++A   P+  PP   +        P PP + PP+            V  
Sbjct: 349 PPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCE 408

Query: 593 AVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAF 652
            VPV P P    V  LPP     P+PP    P I      PS+P  +     P   P+  
Sbjct: 409 TVPVHPLP-QGEVQGLPPPPPPPPLPP----PGIR-----PSSPVTVTALAHP---PSGL 455

Query: 653 VPAPPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
            P P  AP P    MP   P PP +  P S+  K   S +P
Sbjct: 456 HPTPSTAPGPHVPLMP---PSPPSQVIPASEP-KRHPSTLP 492



 Score = 37.7 bits (86), Expect = 0.042
 Identities = 22/63 (34%), Positives = 31/63 (49%), Gaps = 3/63 (4%)

Query: 369 PPPPETPMPPP-LPPTPDQVIVRKDYDPKASKPLP-PAPAPDEYLVSPI-TGEKIPASKM 425
           PPPP  P+PPP + P+    +    + P    P P  AP P   L+ P    + IPAS+ 
Sbjct: 425 PPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEP 484

Query: 426 QEH 428
           + H
Sbjct: 485 KRH 487



 Score = 31.6 bits (70), Expect = 3.0
 Identities = 19/54 (35%), Positives = 22/54 (40%), Gaps = 10/54 (18%)

Query: 369 PPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPA 422
           PPPP    PPPLP       +R         P+PP P P      P T  + PA
Sbjct: 324 PPPP----PPPLPSALSTSSLRASMTSTPPPPVPPPPPP------PATALQAPA 367



 Score = 31.2 bits (69), Expect = 3.9
 Identities = 24/95 (25%), Positives = 32/95 (33%), Gaps = 11/95 (11%)

Query: 553 IPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMA-----SVVR 607
           +P  P P      +P   PP      PP  PP +R +    V  +  PP       S   
Sbjct: 410 VPVHPLPQGEVQGLPPPPPP------PPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAP 463

Query: 608 LPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPR 642
            P   ++ P PP    P       P + P I   R
Sbjct: 464 GPHVPLMPPSPPSQVIPASEPKRHPSTLPVISDAR 498



 Score = 30.8 bits (68), Expect = 5.1
 Identities = 18/47 (38%), Positives = 25/47 (53%), Gaps = 2/47 (4%)

Query: 1   MPAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPP 47
           +P G VQ +PPPPP P  P  P    +S    +A + P  G ++P P
Sbjct: 415 LPQGEVQGLPPPPPPPPLP-PPGIRPSSPVTVTALAHPPSG-LHPTP 459



 Score = 30.4 bits (67), Expect = 6.7
 Identities = 18/63 (28%), Positives = 24/63 (38%), Gaps = 1/63 (1%)

Query: 374 TPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKMQEHMRIGL 433
           TP PPP PP P  +          S P PP P P     + +    +P       +  G+
Sbjct: 323 TPPPPP-PPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGV 381

Query: 434 LDP 436
           L P
Sbjct: 382 LHP 384



 Score = 30.4 bits (67), Expect = 6.7
 Identities = 20/62 (32%), Positives = 23/62 (37%), Gaps = 13/62 (20%)

Query: 369 PPPPETPMPPP---------LPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEK 419
           PPPP  P PPP         +PP P  + +     P    P PP  AP     SP     
Sbjct: 348 PPPPVPPPPPPPATALQAPAVPPPPAPLQIA----PGVLHPAPPPIAPPLVQPSPPVARA 403

Query: 420 IP 421
            P
Sbjct: 404 AP 405



 Score = 30.0 bits (66), Expect = 8.8
 Identities = 19/61 (31%), Positives = 29/61 (47%), Gaps = 3/61 (4%)

Query: 11  PPPPVPTEPKQPTE--EEASSKEDSAPSKPVVGIIYP-PPEVRNIVDKTASFVARNGPEF 67
           PPPPVP  P  P    +  +     AP +   G+++P PP +   + + +  VAR  P  
Sbjct: 348 PPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVC 407

Query: 68  E 68
           E
Sbjct: 408 E 408


>gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 50/157 (31%), Positives = 67/157 (42%), Gaps = 12/157 (7%)

Query: 529 IHKAKGLVPEDDTKEKIGPSKPNEIPQQPPPPS---SATNIPSSAPPITSVPRPPTMPPP 585
           I  A GL+         G +     P  PPPP    SA +  S    +TS P PP  PPP
Sbjct: 297 ISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPP 356

Query: 586 VRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPP 645
                    P +P PP  + +++ PG V+ P PP I AP     P+   +PP+    P  
Sbjct: 357 PPPATALQAPAVPPPP--APLQIAPG-VLHPAPPPI-AP-----PLVQPSPPVARAAPVC 407

Query: 646 MIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPTS 682
             VP   +P   V  +P P P PP+ PP      P +
Sbjct: 408 ETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVT 444



 Score = 63.9 bits (154), Expect = 5e-10
 Identities = 48/146 (32%), Positives = 57/146 (39%), Gaps = 23/146 (15%)

Query: 554 PQQPPPP------SSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPP------ 601
           P +PPPP        A  IP+     T +       P    T V   P  P PP      
Sbjct: 275 PHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSA 334

Query: 602 ------MASVVRLPPGSVIAPMPPIIHAPRINVVPMPPS----APPIMAPRPPPMIVPTA 651
                  AS+   PP  V  P PP   A +   VP PP+    AP ++ P PPP I P  
Sbjct: 335 LSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPP-IAPPL 393

Query: 652 FVPAPPVAPVPAPAPMPPVHPPPPME 677
             P+PPVA         PVHP P  E
Sbjct: 394 VQPSPPVARAAPVCETVPVHPLPQGE 419



 Score = 56.6 bits (135), Expect = 9e-08
 Identities = 50/161 (31%), Positives = 64/161 (39%), Gaps = 34/161 (21%)

Query: 550 PNEIPQQPPPPSSATNIPSSAPPITSV--------PRPPTMPPPV---------RTTVVS 592
           P  +P  PPPP++A   P+  PP   +        P PP + PP+            V  
Sbjct: 349 PPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCE 408

Query: 593 AVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAF 652
            VPV P P    V  LPP     P+PP    P I      PS+P  +     P   P+  
Sbjct: 409 TVPVHPLP-QGEVQGLPPPPPPPPLPP----PGIR-----PSSPVTVTALAHP---PSGL 455

Query: 653 VPAPPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
            P P  AP P    MP   P PP +  P S+  K   S +P
Sbjct: 456 HPTPSTAPGPHVPLMP---PSPPSQVIPASEP-KRHPSTLP 492



 Score = 37.7 bits (86), Expect = 0.042
 Identities = 22/63 (34%), Positives = 31/63 (49%), Gaps = 3/63 (4%)

Query: 369 PPPPETPMPPP-LPPTPDQVIVRKDYDPKASKPLP-PAPAPDEYLVSPI-TGEKIPASKM 425
           PPPP  P+PPP + P+    +    + P    P P  AP P   L+ P    + IPAS+ 
Sbjct: 425 PPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEP 484

Query: 426 QEH 428
           + H
Sbjct: 485 KRH 487



 Score = 31.6 bits (70), Expect = 3.0
 Identities = 19/54 (35%), Positives = 22/54 (40%), Gaps = 10/54 (18%)

Query: 369 PPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPA 422
           PPPP    PPPLP       +R         P+PP P P      P T  + PA
Sbjct: 324 PPPP----PPPLPSALSTSSLRASMTSTPPPPVPPPPPP------PATALQAPA 367



 Score = 31.2 bits (69), Expect = 3.9
 Identities = 24/95 (25%), Positives = 32/95 (33%), Gaps = 11/95 (11%)

Query: 553 IPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMA-----SVVR 607
           +P  P P      +P   PP      PP  PP +R +    V  +  PP       S   
Sbjct: 410 VPVHPLPQGEVQGLPPPPPP------PPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAP 463

Query: 608 LPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPR 642
            P   ++ P PP    P       P + P I   R
Sbjct: 464 GPHVPLMPPSPPSQVIPASEPKRHPSTLPVISDAR 498



 Score = 30.8 bits (68), Expect = 5.1
 Identities = 18/47 (38%), Positives = 25/47 (53%), Gaps = 2/47 (4%)

Query: 1   MPAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPP 47
           +P G VQ +PPPPP P  P  P    +S    +A + P  G ++P P
Sbjct: 415 LPQGEVQGLPPPPPPPPLP-PPGIRPSSPVTVTALAHPPSG-LHPTP 459



 Score = 30.4 bits (67), Expect = 6.7
 Identities = 18/63 (28%), Positives = 24/63 (38%), Gaps = 1/63 (1%)

Query: 374 TPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKMQEHMRIGL 433
           TP PPP PP P  +          S P PP P P     + +    +P       +  G+
Sbjct: 323 TPPPPP-PPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGV 381

Query: 434 LDP 436
           L P
Sbjct: 382 LHP 384



 Score = 30.4 bits (67), Expect = 6.7
 Identities = 20/62 (32%), Positives = 23/62 (37%), Gaps = 13/62 (20%)

Query: 369 PPPPETPMPPP---------LPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEK 419
           PPPP  P PPP         +PP P  + +     P    P PP  AP     SP     
Sbjct: 348 PPPPVPPPPPPPATALQAPAVPPPPAPLQIA----PGVLHPAPPPIAPPLVQPSPPVARA 403

Query: 420 IP 421
            P
Sbjct: 404 AP 405



 Score = 30.0 bits (66), Expect = 8.8
 Identities = 19/61 (31%), Positives = 29/61 (47%), Gaps = 3/61 (4%)

Query: 11  PPPPVPTEPKQPTE--EEASSKEDSAPSKPVVGIIYP-PPEVRNIVDKTASFVARNGPEF 67
           PPPPVP  P  P    +  +     AP +   G+++P PP +   + + +  VAR  P  
Sbjct: 348 PPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVC 407

Query: 68  E 68
           E
Sbjct: 408 E 408


>gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 50/157 (31%), Positives = 67/157 (42%), Gaps = 12/157 (7%)

Query: 529 IHKAKGLVPEDDTKEKIGPSKPNEIPQQPPPPS---SATNIPSSAPPITSVPRPPTMPPP 585
           I  A GL+         G +     P  PPPP    SA +  S    +TS P PP  PPP
Sbjct: 297 ISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPP 356

Query: 586 VRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPP 645
                    P +P PP  + +++ PG V+ P PP I AP     P+   +PP+    P  
Sbjct: 357 PPPATALQAPAVPPPP--APLQIAPG-VLHPAPPPI-AP-----PLVQPSPPVARAAPVC 407

Query: 646 MIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPTS 682
             VP   +P   V  +P P P PP+ PP      P +
Sbjct: 408 ETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVT 444



 Score = 63.9 bits (154), Expect = 5e-10
 Identities = 48/146 (32%), Positives = 57/146 (39%), Gaps = 23/146 (15%)

Query: 554 PQQPPPP------SSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPP------ 601
           P +PPPP        A  IP+     T +       P    T V   P  P PP      
Sbjct: 275 PHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSA 334

Query: 602 ------MASVVRLPPGSVIAPMPPIIHAPRINVVPMPPS----APPIMAPRPPPMIVPTA 651
                  AS+   PP  V  P PP   A +   VP PP+    AP ++ P PPP I P  
Sbjct: 335 LSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPP-IAPPL 393

Query: 652 FVPAPPVAPVPAPAPMPPVHPPPPME 677
             P+PPVA         PVHP P  E
Sbjct: 394 VQPSPPVARAAPVCETVPVHPLPQGE 419



 Score = 56.6 bits (135), Expect = 9e-08
 Identities = 50/161 (31%), Positives = 64/161 (39%), Gaps = 34/161 (21%)

Query: 550 PNEIPQQPPPPSSATNIPSSAPPITSV--------PRPPTMPPPV---------RTTVVS 592
           P  +P  PPPP++A   P+  PP   +        P PP + PP+            V  
Sbjct: 349 PPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCE 408

Query: 593 AVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAF 652
            VPV P P    V  LPP     P+PP    P I      PS+P  +     P   P+  
Sbjct: 409 TVPVHPLP-QGEVQGLPPPPPPPPLPP----PGIR-----PSSPVTVTALAHP---PSGL 455

Query: 653 VPAPPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
            P P  AP P    MP   P PP +  P S+  K   S +P
Sbjct: 456 HPTPSTAPGPHVPLMP---PSPPSQVIPASEP-KRHPSTLP 492



 Score = 37.7 bits (86), Expect = 0.042
 Identities = 22/63 (34%), Positives = 31/63 (49%), Gaps = 3/63 (4%)

Query: 369 PPPPETPMPPP-LPPTPDQVIVRKDYDPKASKPLP-PAPAPDEYLVSPI-TGEKIPASKM 425
           PPPP  P+PPP + P+    +    + P    P P  AP P   L+ P    + IPAS+ 
Sbjct: 425 PPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEP 484

Query: 426 QEH 428
           + H
Sbjct: 485 KRH 487



 Score = 31.6 bits (70), Expect = 3.0
 Identities = 19/54 (35%), Positives = 22/54 (40%), Gaps = 10/54 (18%)

Query: 369 PPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPA 422
           PPPP    PPPLP       +R         P+PP P P      P T  + PA
Sbjct: 324 PPPP----PPPLPSALSTSSLRASMTSTPPPPVPPPPPP------PATALQAPA 367



 Score = 31.2 bits (69), Expect = 3.9
 Identities = 24/95 (25%), Positives = 32/95 (33%), Gaps = 11/95 (11%)

Query: 553 IPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMA-----SVVR 607
           +P  P P      +P   PP      PP  PP +R +    V  +  PP       S   
Sbjct: 410 VPVHPLPQGEVQGLPPPPPP------PPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAP 463

Query: 608 LPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPR 642
            P   ++ P PP    P       P + P I   R
Sbjct: 464 GPHVPLMPPSPPSQVIPASEPKRHPSTLPVISDAR 498



 Score = 30.8 bits (68), Expect = 5.1
 Identities = 18/47 (38%), Positives = 25/47 (53%), Gaps = 2/47 (4%)

Query: 1   MPAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPP 47
           +P G VQ +PPPPP P  P  P    +S    +A + P  G ++P P
Sbjct: 415 LPQGEVQGLPPPPPPPPLP-PPGIRPSSPVTVTALAHPPSG-LHPTP 459



 Score = 30.4 bits (67), Expect = 6.7
 Identities = 18/63 (28%), Positives = 24/63 (38%), Gaps = 1/63 (1%)

Query: 374 TPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKMQEHMRIGL 433
           TP PPP PP P  +          S P PP P P     + +    +P       +  G+
Sbjct: 323 TPPPPP-PPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGV 381

Query: 434 LDP 436
           L P
Sbjct: 382 LHP 384



 Score = 30.4 bits (67), Expect = 6.7
 Identities = 20/62 (32%), Positives = 23/62 (37%), Gaps = 13/62 (20%)

Query: 369 PPPPETPMPPP---------LPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEK 419
           PPPP  P PPP         +PP P  + +     P    P PP  AP     SP     
Sbjct: 348 PPPPVPPPPPPPATALQAPAVPPPPAPLQIA----PGVLHPAPPPIAPPLVQPSPPVARA 403

Query: 420 IP 421
            P
Sbjct: 404 AP 405



 Score = 30.0 bits (66), Expect = 8.8
 Identities = 19/61 (31%), Positives = 29/61 (47%), Gaps = 3/61 (4%)

Query: 11  PPPPVPTEPKQPTE--EEASSKEDSAPSKPVVGIIYP-PPEVRNIVDKTASFVARNGPEF 67
           PPPPVP  P  P    +  +     AP +   G+++P PP +   + + +  VAR  P  
Sbjct: 348 PPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVC 407

Query: 68  E 68
           E
Sbjct: 408 E 408


>gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 50/157 (31%), Positives = 67/157 (42%), Gaps = 12/157 (7%)

Query: 529 IHKAKGLVPEDDTKEKIGPSKPNEIPQQPPPPS---SATNIPSSAPPITSVPRPPTMPPP 585
           I  A GL+         G +     P  PPPP    SA +  S    +TS P PP  PPP
Sbjct: 297 ISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPP 356

Query: 586 VRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPP 645
                    P +P PP  + +++ PG V+ P PP I AP     P+   +PP+    P  
Sbjct: 357 PPPATALQAPAVPPPP--APLQIAPG-VLHPAPPPI-AP-----PLVQPSPPVARAAPVC 407

Query: 646 MIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPTS 682
             VP   +P   V  +P P P PP+ PP      P +
Sbjct: 408 ETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVT 444



 Score = 63.9 bits (154), Expect = 5e-10
 Identities = 48/146 (32%), Positives = 57/146 (39%), Gaps = 23/146 (15%)

Query: 554 PQQPPPP------SSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPP------ 601
           P +PPPP        A  IP+     T +       P    T V   P  P PP      
Sbjct: 275 PHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSA 334

Query: 602 ------MASVVRLPPGSVIAPMPPIIHAPRINVVPMPPS----APPIMAPRPPPMIVPTA 651
                  AS+   PP  V  P PP   A +   VP PP+    AP ++ P PPP I P  
Sbjct: 335 LSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPP-IAPPL 393

Query: 652 FVPAPPVAPVPAPAPMPPVHPPPPME 677
             P+PPVA         PVHP P  E
Sbjct: 394 VQPSPPVARAAPVCETVPVHPLPQGE 419



 Score = 56.6 bits (135), Expect = 9e-08
 Identities = 50/161 (31%), Positives = 64/161 (39%), Gaps = 34/161 (21%)

Query: 550 PNEIPQQPPPPSSATNIPSSAPPITSV--------PRPPTMPPPV---------RTTVVS 592
           P  +P  PPPP++A   P+  PP   +        P PP + PP+            V  
Sbjct: 349 PPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCE 408

Query: 593 AVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAF 652
            VPV P P    V  LPP     P+PP    P I      PS+P  +     P   P+  
Sbjct: 409 TVPVHPLP-QGEVQGLPPPPPPPPLPP----PGIR-----PSSPVTVTALAHP---PSGL 455

Query: 653 VPAPPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
            P P  AP P    MP   P PP +  P S+  K   S +P
Sbjct: 456 HPTPSTAPGPHVPLMP---PSPPSQVIPASEP-KRHPSTLP 492



 Score = 37.7 bits (86), Expect = 0.042
 Identities = 22/63 (34%), Positives = 31/63 (49%), Gaps = 3/63 (4%)

Query: 369 PPPPETPMPPP-LPPTPDQVIVRKDYDPKASKPLP-PAPAPDEYLVSPI-TGEKIPASKM 425
           PPPP  P+PPP + P+    +    + P    P P  AP P   L+ P    + IPAS+ 
Sbjct: 425 PPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEP 484

Query: 426 QEH 428
           + H
Sbjct: 485 KRH 487



 Score = 31.6 bits (70), Expect = 3.0
 Identities = 19/54 (35%), Positives = 22/54 (40%), Gaps = 10/54 (18%)

Query: 369 PPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPA 422
           PPPP    PPPLP       +R         P+PP P P      P T  + PA
Sbjct: 324 PPPP----PPPLPSALSTSSLRASMTSTPPPPVPPPPPP------PATALQAPA 367



 Score = 31.2 bits (69), Expect = 3.9
 Identities = 24/95 (25%), Positives = 32/95 (33%), Gaps = 11/95 (11%)

Query: 553 IPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMA-----SVVR 607
           +P  P P      +P   PP      PP  PP +R +    V  +  PP       S   
Sbjct: 410 VPVHPLPQGEVQGLPPPPPP------PPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAP 463

Query: 608 LPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPR 642
            P   ++ P PP    P       P + P I   R
Sbjct: 464 GPHVPLMPPSPPSQVIPASEPKRHPSTLPVISDAR 498



 Score = 30.8 bits (68), Expect = 5.1
 Identities = 18/47 (38%), Positives = 25/47 (53%), Gaps = 2/47 (4%)

Query: 1   MPAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPP 47
           +P G VQ +PPPPP P  P  P    +S    +A + P  G ++P P
Sbjct: 415 LPQGEVQGLPPPPPPPPLP-PPGIRPSSPVTVTALAHPPSG-LHPTP 459



 Score = 30.4 bits (67), Expect = 6.7
 Identities = 18/63 (28%), Positives = 24/63 (38%), Gaps = 1/63 (1%)

Query: 374 TPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKMQEHMRIGL 433
           TP PPP PP P  +          S P PP P P     + +    +P       +  G+
Sbjct: 323 TPPPPP-PPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGV 381

Query: 434 LDP 436
           L P
Sbjct: 382 LHP 384



 Score = 30.4 bits (67), Expect = 6.7
 Identities = 20/62 (32%), Positives = 23/62 (37%), Gaps = 13/62 (20%)

Query: 369 PPPPETPMPPP---------LPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEK 419
           PPPP  P PPP         +PP P  + +     P    P PP  AP     SP     
Sbjct: 348 PPPPVPPPPPPPATALQAPAVPPPPAPLQIA----PGVLHPAPPPIAPPLVQPSPPVARA 403

Query: 420 IP 421
            P
Sbjct: 404 AP 405



 Score = 30.0 bits (66), Expect = 8.8
 Identities = 19/61 (31%), Positives = 29/61 (47%), Gaps = 3/61 (4%)

Query: 11  PPPPVPTEPKQPTE--EEASSKEDSAPSKPVVGIIYP-PPEVRNIVDKTASFVARNGPEF 67
           PPPPVP  P  P    +  +     AP +   G+++P PP +   + + +  VAR  P  
Sbjct: 348 PPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVC 407

Query: 68  E 68
           E
Sbjct: 408 E 408


>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
          Length = 1263

 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 51/156 (32%), Positives = 67/156 (42%), Gaps = 23/156 (14%)

Query: 545 IGPSKPNEIPQQPPPP---SSATNIPSSAPPITSV-----PRPPTMPPPVRTTVVSAVP- 595
           + PS P+  P  P PP    S T IP    P  S      P PP  PPP+   V  + P 
Sbjct: 563 VPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPP 622

Query: 596 -------VMPRPPMASVVRLPPGSVIAP---MPPIIHAPRINVVPMPPSAP-PIMAPRPP 644
                  + P PP++    +PP   +     +P     P    +P PP  P     P PP
Sbjct: 623 SLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPP 682

Query: 645 PMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEP 680
           P +  +A +P PP  P+P  A MPP  PPPP+   P
Sbjct: 683 PPLPGSAGIPPPP-PPLPGEAGMPP--PPPPLPGGP 715



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 59/190 (31%), Positives = 81/190 (42%), Gaps = 30/190 (15%)

Query: 513 QQAAQANITLQEQIEAI--HKAKGLVPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSA 570
           QQ A     L+ ++  +    AK     +D K+++       I   P  PS A   P  A
Sbjct: 519 QQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPP--A 576

Query: 571 PPI-----TSVPRPPTMPPPVRTTVVSAVPVMPRPP-------MASVVRLPPGSVIAPMP 618
           PP+     T +P PP   P   TT     P  P PP       ++S   LP G+ I+P P
Sbjct: 577 PPLPGDSGTIIPPPPA--PGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPP 634

Query: 619 PII---------HAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPP 669
           P+            P    +P P S P   A  PPP +  +A +P PP  P+P  A +PP
Sbjct: 635 PLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPP-PPLPGSAGIPP 693

Query: 670 VHPPPPMEDE 679
             PPPP+  E
Sbjct: 694 --PPPPLPGE 701



 Score = 58.2 bits (139), Expect = 3e-08
 Identities = 48/156 (30%), Positives = 63/156 (40%), Gaps = 32/156 (20%)

Query: 550 PNEIPQQPPPP-------SSATNIP-----SSAPPIT---SVPRPPTMPPPVRTTVVSAV 594
           P   P  PPPP       SS  ++P     S  PP++   ++P PP +P  V     S++
Sbjct: 601 PPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSL 660

Query: 595 P----VMPRPPMASVVRLPP------GSVIAPMPPIIHAPRINVVPMPPSAPPIMA---- 640
           P    + P PP+    R+PP      GS   P PP    P      MPP  PP+      
Sbjct: 661 PGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPP---PPLPGEAGMPPPPPPLPGGPGI 717

Query: 641 PRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPM 676
           P PPP        P PP   +P P P     P  P+
Sbjct: 718 PPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPV 753



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 48/150 (32%), Positives = 58/150 (38%), Gaps = 27/150 (18%)

Query: 557 PPPPSSATNI----PSSAPPITSVPRPPTMP------PPVRTTVVSAVPVMPRPPMASVV 606
           PPPP     +    PSS P  T++P PP +P      PP      SA    P PP+    
Sbjct: 643 PPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEA 702

Query: 607 RLPP-------GSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVA 659
            +PP       G  I P PP    P I     PP  P +  P PPP       VPA PV 
Sbjct: 703 GMPPPPPPLPGGPGIPPPPPFPGGPGI-----PPPPPGMGMPPPPPF---GFGVPAAPV- 753

Query: 660 PVPAPAPMPPVHPPPPMEDEPTSKKLKTED 689
            +P       ++ P      P   KL  ED
Sbjct: 754 -LPFGLTPKKLYKPEVQLRRPNWSKLVAED 782



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 24/71 (33%), Positives = 32/71 (45%), Gaps = 2/71 (2%)

Query: 621 IHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEP 680
           + A  I V P  PS  P+  P  PP+   +  +  PP AP  +  P PP  PPPP    P
Sbjct: 556 LSAAAITVPPSVPSRAPV--PPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLP 613

Query: 681 TSKKLKTEDSL 691
               + +  SL
Sbjct: 614 GGVCISSPPSL 624



 Score = 35.8 bits (81), Expect = 0.16
 Identities = 19/50 (38%), Positives = 23/50 (46%), Gaps = 7/50 (14%)

Query: 365 GQKVPPPPETP----MPPPLPPTPDQVIVRKDYDP---KASKPLPPAPAP 407
           G  +PPPP  P    +PPP PP P    +     P   +A  P PP P P
Sbjct: 663 GTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLP 712



 Score = 35.4 bits (80), Expect = 0.21
 Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 21/92 (22%)

Query: 603 ASVVRLPPGSVI-APMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPV 661
           A+ + +PP     AP+PP   AP     P+P  +  I+ P P P    T   P PP  P 
Sbjct: 558 AAAITVPPSVPSRAPVPP---AP-----PLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPP 609

Query: 662 P---------APAPMP---PVHPPPPMEDEPT 681
           P         +P  +P    + PPPP+  + T
Sbjct: 610 PPLPGGVCISSPPSLPGGTAISPPPPLSGDAT 641



 Score = 34.7 bits (78), Expect = 0.36
 Identities = 17/51 (33%), Positives = 21/51 (41%), Gaps = 1/51 (1%)

Query: 365 GQKVPPPPETPMPPPLPPTPDQVIVRKDYD-PKASKPLPPAPAPDEYLVSP 414
           G    PPP  P PPP PP P  V +      P  +   PP P   +  + P
Sbjct: 594 GDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPP 644



 Score = 30.4 bits (67), Expect = 6.7
 Identities = 17/47 (36%), Positives = 21/47 (44%), Gaps = 14/47 (29%)

Query: 1   MPAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPP 47
           +P GP   +PPPPP P  P  P            P  P +G+  PPP
Sbjct: 711 LPGGP--GIPPPPPFPGGPGIP------------PPPPGMGMPPPPP 743



 Score = 30.0 bits (66), Expect = 8.8
 Identities = 13/27 (48%), Positives = 15/27 (55%), Gaps = 5/27 (18%)

Query: 363 EEGQKVPPPPE-----TPMPPPLPPTP 384
           + G  +PPPP      TP PPP PP P
Sbjct: 582 DSGTIIPPPPAPGDSTTPPPPPPPPPP 608


>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
          Length = 1272

 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 51/156 (32%), Positives = 67/156 (42%), Gaps = 23/156 (14%)

Query: 545 IGPSKPNEIPQQPPPP---SSATNIPSSAPPITSV-----PRPPTMPPPVRTTVVSAVP- 595
           + PS P+  P  P PP    S T IP    P  S      P PP  PPP+   V  + P 
Sbjct: 572 VPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPP 631

Query: 596 -------VMPRPPMASVVRLPPGSVIAP---MPPIIHAPRINVVPMPPSAP-PIMAPRPP 644
                  + P PP++    +PP   +     +P     P    +P PP  P     P PP
Sbjct: 632 SLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPP 691

Query: 645 PMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEP 680
           P +  +A +P PP  P+P  A MPP  PPPP+   P
Sbjct: 692 PPLPGSAGIPPPP-PPLPGEAGMPP--PPPPLPGGP 724



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 59/190 (31%), Positives = 81/190 (42%), Gaps = 30/190 (15%)

Query: 513 QQAAQANITLQEQIEAI--HKAKGLVPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSA 570
           QQ A     L+ ++  +    AK     +D K+++       I   P  PS A   P  A
Sbjct: 528 QQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPP--A 585

Query: 571 PPI-----TSVPRPPTMPPPVRTTVVSAVPVMPRPP-------MASVVRLPPGSVIAPMP 618
           PP+     T +P PP   P   TT     P  P PP       ++S   LP G+ I+P P
Sbjct: 586 PPLPGDSGTIIPPPPA--PGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPP 643

Query: 619 PII---------HAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPP 669
           P+            P    +P P S P   A  PPP +  +A +P PP  P+P  A +PP
Sbjct: 644 PLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPP-PPLPGSAGIPP 702

Query: 670 VHPPPPMEDE 679
             PPPP+  E
Sbjct: 703 --PPPPLPGE 710



 Score = 58.2 bits (139), Expect = 3e-08
 Identities = 48/156 (30%), Positives = 63/156 (40%), Gaps = 32/156 (20%)

Query: 550 PNEIPQQPPPP-------SSATNIP-----SSAPPIT---SVPRPPTMPPPVRTTVVSAV 594
           P   P  PPPP       SS  ++P     S  PP++   ++P PP +P  V     S++
Sbjct: 610 PPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSL 669

Query: 595 P----VMPRPPMASVVRLPP------GSVIAPMPPIIHAPRINVVPMPPSAPPIMA---- 640
           P    + P PP+    R+PP      GS   P PP    P      MPP  PP+      
Sbjct: 670 PGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPP---PPLPGEAGMPPPPPPLPGGPGI 726

Query: 641 PRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPM 676
           P PPP        P PP   +P P P     P  P+
Sbjct: 727 PPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPV 762



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 48/150 (32%), Positives = 58/150 (38%), Gaps = 27/150 (18%)

Query: 557 PPPPSSATNI----PSSAPPITSVPRPPTMP------PPVRTTVVSAVPVMPRPPMASVV 606
           PPPP     +    PSS P  T++P PP +P      PP      SA    P PP+    
Sbjct: 652 PPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEA 711

Query: 607 RLPP-------GSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVA 659
            +PP       G  I P PP    P I     PP  P +  P PPP       VPA PV 
Sbjct: 712 GMPPPPPPLPGGPGIPPPPPFPGGPGI-----PPPPPGMGMPPPPPF---GFGVPAAPV- 762

Query: 660 PVPAPAPMPPVHPPPPMEDEPTSKKLKTED 689
            +P       ++ P      P   KL  ED
Sbjct: 763 -LPFGLTPKKLYKPEVQLRRPNWSKLVAED 791



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 24/71 (33%), Positives = 32/71 (45%), Gaps = 2/71 (2%)

Query: 621 IHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEP 680
           + A  I V P  PS  P+  P  PP+   +  +  PP AP  +  P PP  PPPP    P
Sbjct: 565 LSAAAITVPPSVPSRAPV--PPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLP 622

Query: 681 TSKKLKTEDSL 691
               + +  SL
Sbjct: 623 GGVCISSPPSL 633



 Score = 35.8 bits (81), Expect = 0.16
 Identities = 19/50 (38%), Positives = 23/50 (46%), Gaps = 7/50 (14%)

Query: 365 GQKVPPPPETP----MPPPLPPTPDQVIVRKDYDP---KASKPLPPAPAP 407
           G  +PPPP  P    +PPP PP P    +     P   +A  P PP P P
Sbjct: 672 GTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLP 721



 Score = 35.4 bits (80), Expect = 0.21
 Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 21/92 (22%)

Query: 603 ASVVRLPPGSVI-APMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPV 661
           A+ + +PP     AP+PP   AP     P+P  +  I+ P P P    T   P PP  P 
Sbjct: 567 AAAITVPPSVPSRAPVPP---AP-----PLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPP 618

Query: 662 P---------APAPMP---PVHPPPPMEDEPT 681
           P         +P  +P    + PPPP+  + T
Sbjct: 619 PPLPGGVCISSPPSLPGGTAISPPPPLSGDAT 650



 Score = 34.7 bits (78), Expect = 0.36
 Identities = 17/51 (33%), Positives = 21/51 (41%), Gaps = 1/51 (1%)

Query: 365 GQKVPPPPETPMPPPLPPTPDQVIVRKDYD-PKASKPLPPAPAPDEYLVSP 414
           G    PPP  P PPP PP P  V +      P  +   PP P   +  + P
Sbjct: 603 GDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPP 653



 Score = 30.4 bits (67), Expect = 6.7
 Identities = 17/47 (36%), Positives = 21/47 (44%), Gaps = 14/47 (29%)

Query: 1   MPAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPP 47
           +P GP   +PPPPP P  P  P            P  P +G+  PPP
Sbjct: 720 LPGGP--GIPPPPPFPGGPGIP------------PPPPGMGMPPPPP 752



 Score = 30.0 bits (66), Expect = 8.8
 Identities = 13/27 (48%), Positives = 15/27 (55%), Gaps = 5/27 (18%)

Query: 363 EEGQKVPPPPE-----TPMPPPLPPTP 384
           + G  +PPPP      TP PPP PP P
Sbjct: 591 DSGTIIPPPPAPGDSTTPPPPPPPPPP 617


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
           sapiens]
          Length = 5537

 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 88/387 (22%), Positives = 135/387 (34%), Gaps = 95/387 (24%)

Query: 363 EEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPA 422
           EE   +PPP E+P+ PP               P+ S   P +P P+   +SP   E++PA
Sbjct: 436 EEMPLLPPPEESPLSPP---------------PEES---PTSPPPEASRLSP-PPEELPA 476

Query: 423 SKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGVEET 482
           S + E + +                                               +EE+
Sbjct: 477 SPLPEALHLSR--------------------------------------------PLEES 492

Query: 483 AIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKAKGLVPEDDTK 542
            +     E  +  P E   +     S     + +  +  L+  +    +A  L P  +  
Sbjct: 493 PLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEES 552

Query: 543 EKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRP-PTMPPPVRTTVVSAVPVMP-RP 600
               P  P E+P  PPP +S  + P    P++  P   P  PPP  + +       P  P
Sbjct: 553 PLSPP--PEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSP 610

Query: 601 PMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAP 660
           P       PP       PP   +P        P +PP    R  P+ V +   P P  +P
Sbjct: 611 PPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESP 670

Query: 661 VPAPAPMPPVHPP-------PPMEDEPTSKKLK-------TEDSLM------------PE 694
           +  P    P  PP       PP ED PTS   +        EDSLM            PE
Sbjct: 671 LSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPE 730

Query: 695 E-EFLRRNKGP-VSIKVQVPNMQDKTE 719
           E +   R++GP +S + + P++  + E
Sbjct: 731 EPQLCPRSEGPHLSPRPEEPHLSPRPE 757



 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 90/355 (25%), Positives = 130/355 (36%), Gaps = 54/355 (15%)

Query: 363 EEGQKVPPPPETPMPPP-----LPPTPDQVIVRKDYDPKA---SKPL---PPAPAPDEYL 411
           EE    PPP E+P  PP     L P P+++       P+A   S+PL   P +P P+E  
Sbjct: 445 EESPLSPPPEESPTSPPPEASRLSPPPEELPASPL--PEALHLSRPLEESPLSPPPEESP 502

Query: 412 VSPITGEKIPASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAE 471
           +SP   E  P S ++E                       S  E   P   +E+ L    E
Sbjct: 503 LSP-PPESSPFSPLEE--------------------SPLSPPEESPPSPALETPLSPPPE 541

Query: 472 RRTDIFGVEETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHK 531
                   EE+ +     E     P E       S      +++  +    +  +    +
Sbjct: 542 ASPLSPPFEESPLSPPPEELPTSPPPEA------SRLSPPPEESPMSPPPEESPMSPPPE 595

Query: 532 AKGLVPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVV 591
           A  L P  +      P  P E P  PPP +S  + P    P++  P    M PP   + +
Sbjct: 596 ASRLFPPFEESPLSPP--PEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRL 653

Query: 592 SAVPVMPR---PPMASVVRLPPGSVIAPMPPIIHAPRINVVP--MPPSAPPIMAPRPPP- 645
           S +PV+ R   PP  S +  PP    +P  P   A R++  P   P S PP  +P  PP 
Sbjct: 654 SPLPVVSRLSPPPEESPLSPPPEE--SPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPP 711

Query: 646 ----MIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMPEEE 696
               M +P    P  P+   P   P        P  +EP       E  L P+ E
Sbjct: 712 EDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAE 766



 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 60/227 (26%), Positives = 88/227 (38%), Gaps = 40/227 (17%)

Query: 517 QANITLQEQIEA-IHKAKGLVPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITS 575
           +A + L+ Q+EA +++   L+P  +      P  P E P  PPP +S  + P    P + 
Sbjct: 421 KAGVQLEPQLEAPLNEEMPLLPPPEESPLSPP--PEESPTSPPPEASRLSPPPEELPASP 478

Query: 576 VP------RP----PTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPR 625
           +P      RP    P  PPP  + +       P  P+      PP    +P  P +  P 
Sbjct: 479 LPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEE--SPPSPALETP- 535

Query: 626 INVVPMPPSAPPIMAP------RPPPMIVPTA-------FVPAPPVAPVPAPAPMPPVHP 672
              +  PP A P+  P       PPP  +PT+         P P  +P+  P    P+ P
Sbjct: 536 ---LSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSP 592

Query: 673 P-------PPMEDEPTSKKLKTEDSLMPEEEFLRRNKGPVSIKVQVP 712
           P       PP E+ P S     E  L P  E  R +  P    +  P
Sbjct: 593 PPEASRLFPPFEESPLSPP-PEESPLSPPPEASRLSPPPEDSPMSPP 638



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 96/447 (21%), Positives = 154/447 (34%), Gaps = 92/447 (20%)

Query: 336  QEKAEEPPSQLDQDTQVQDMDEGSDDEEEGQKVPPPPETPMPPP------LPPTPDQVIV 389
            +E    PP ++ + + +  +   S   EE    PPP E+P  PP       PP  D    
Sbjct: 640  EESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTS 699

Query: 390  RKDYDPKASKP------------LPPAPAPDEYLVSPIT-GEKIPASKMQEHMRIGLLDP 436
                D  AS P             P  P P+E  + P + G  +     + H+     +P
Sbjct: 700  PPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEP 759

Query: 437  RWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGVEETAIGKKIGEEEIQKP 496
                Q +      Q ++      +  E  L   AE        EE  +  +  E  +   
Sbjct: 760  HLSPQAEEPHLSPQPEEPCLC-AVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPV 818

Query: 497  EEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKAKGLV-------PEDDTKEKIGPSK 549
             E+            + Q+ +    L  + E  H +  L        PE   +E      
Sbjct: 819  PEEPCLSPQPEESHLSPQSEEP--CLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPA 876

Query: 550  PNEIPQQPPP--PSSATNIPSSA------PPITSVPR------------------PPTMP 583
            P E+P  PPP  PS +  +   A      PP++ +P                   P  +P
Sbjct: 877  PEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLP 936

Query: 584  PPVRTTVVSAVPVM------------------PRPPMASVVRLPPGSVIA--------PM 617
            PP+   + +A P                    P  P+A+ +   P S           P+
Sbjct: 937  PPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPV 996

Query: 618  PPIIHAPRINVVPMPPSAPPIMAPRPPPM-------IVPTAFVPA---PPVAPVPAPAPM 667
            PP+I  P     P+ P++P +M P PP         +VP    P+   PP  P+  P+P+
Sbjct: 997  PPMILPPSPGS-PVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPL 1055

Query: 668  PPVHPPPPMEDEPTSKKLKTEDSLMPE 694
             P+     + DE    +++TE    PE
Sbjct: 1056 SPIGKVVGVSDEAELHEMETEKVSEPE 1082



 Score = 53.5 bits (127), Expect = 7e-07
 Identities = 86/394 (21%), Positives = 134/394 (34%), Gaps = 60/394 (15%)

Query: 363 EEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPA------PAPDEYLVSPIT 416
           EE    PPP E+P+ PP   +P   +      P    P  PA      P P+   +SP  
Sbjct: 490 EESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSP-P 548

Query: 417 GEKIPASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAERRTDI 476
            E+ P S   E +      P         +     +  +  P  +   S    A R    
Sbjct: 549 FEESPLSPPPEEL------PTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPP 602

Query: 477 FGVEETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHK---AK 533
           F  EE+ +     E  +  P E             +    ++ ++   ++  +       
Sbjct: 603 F--EESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVS 660

Query: 534 GLVPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRP-PTMPPP---VRTT 589
            L P  +      P  P E P  PPP +S  + P    P +  P   P  PPP   + + 
Sbjct: 661 RLSPPPEESPLSPP--PEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSL 718

Query: 590 VVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIH-APRINVVPMPPSAP-PIMAPRPP--- 644
            +   P++P P    +     G  ++P P   H +PR     + P A  P ++P+P    
Sbjct: 719 PLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPC 778

Query: 645 -------PMIVPTAFVP----------------APPVAPVP---APAPMPPVHPPPPMED 678
                  P + P A  P                 P ++PVP     +P P      P  +
Sbjct: 779 LCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSE 838

Query: 679 EPTSKKLKTEDSLMPEEEFLRRNKGPVSIKVQVP 712
           EP       E  L PE E     K P+S + + P
Sbjct: 839 EPCLSPRPEESHLSPELE-----KPPLSPRPEKP 867



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 82/389 (21%), Positives = 134/389 (34%), Gaps = 56/389 (14%)

Query: 336 QEKAEEPPSQLDQDTQVQDMDEGSDDEEEGQKVPPPPETPMPPP--------------LP 381
           +E    PP +    +   +    S   E+    PPP E+PM PP              L 
Sbjct: 604 EESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLS 663

Query: 382 PTPDQVIVRKDYD-------PKASKPLPP------APAPDEYLVSPITGEKIPASKMQEH 428
           P P++  +    +       P+AS+  PP      +P P++   SP   + + +  ++E 
Sbjct: 664 PPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEES 723

Query: 429 MRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGVEETAIGKKI 488
             + L +   L  R          +E +      E  L   AE        EE  +    
Sbjct: 724 PLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVP 783

Query: 489 GEEEIQKPEEKVTWDGHSGSMARTQQAAQANIT-------LQEQIEAIHKAKGLVPEDDT 541
            E  +    E          +  + Q  + +++       L  Q E  H    L P+  +
Sbjct: 784 EEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESH----LSPQ--S 837

Query: 542 KEKIGPSKPNEIPQQP----PPPSSATNIPSSAPPITSVPRP-PTMPPPVRTTV--VSAV 594
           +E     +P E    P    PP S     P   P     P   P  PPP   ++  +   
Sbjct: 838 EEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGE 897

Query: 595 PVMPRPPMASVVRLPPGSVIAPM-PPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFV 653
           P +  P    +  LP    ++P   P +    +   P+PP   PI+    PP + P   +
Sbjct: 898 PALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGEL 957

Query: 654 PAP--------PVAPVPAPAPMPPVHPPP 674
             P        P +P+ AP    P+ PPP
Sbjct: 958 EYPFGAKGDSDPESPLAAPILETPISPPP 986



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 88/423 (20%), Positives = 139/423 (32%), Gaps = 61/423 (14%)

Query: 289 PNEQGNFPPPTT------PEELGARILIQERYEKFGESEEVEMEVESDEEDDKQEKAEEP 342
           P E    PPP        PEEL A  L           E + +    +E        E P
Sbjct: 453 PEESPTSPPPEASRLSPPPEELPASPL----------PEALHLSRPLEESPLSPPPEESP 502

Query: 343 PSQLDQDTQVQDMDEGSDDEEEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLP 402
            S   + +    ++E      E     P  ETP+ PP   +P          P    PL 
Sbjct: 503 LSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLS-------PPFEESPLS 555

Query: 403 PAPAPDEYLVSPITGEKIPASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDI 462
           P P            E++P S   E  R+                    ++   +P  + 
Sbjct: 556 PPP------------EELPTSPPPEASRL----------------SPPPEESPMSPPPE- 586

Query: 463 ESSLKQLAERRTDIFGVEETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITL 522
           ES +    E        EE+ +     E  +  P E             +    ++ ++ 
Sbjct: 587 ESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSP 646

Query: 523 QEQIEAIHKAKGLVPEDDTKEKIGPSKP-NEIPQQPPPPSSATNIPSSAPPITSVPR-PP 580
             ++  +     +       E+   S P  E P  PPP +S  + P    P +  P   P
Sbjct: 647 PPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSP 706

Query: 581 TMPPP---VRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIH-APRINVVPMPPSA- 635
             PPP   + +  +   P++P P    +     G  ++P P   H +PR     + P A 
Sbjct: 707 ASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAE 766

Query: 636 PPIMAPRP-PPMIVPTAFVP-APPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMP 693
            P ++P+P  P +      P   P A  P  +P P      P  +EP    +  E  L P
Sbjct: 767 EPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSP 826

Query: 694 EEE 696
           + E
Sbjct: 827 QPE 829



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 76/362 (20%), Positives = 125/362 (34%), Gaps = 52/362 (14%)

Query: 336 QEKAEEPPSQLDQDTQVQDMDEGSDDEEEGQKVPPPPETPMPPP------LPPTPDQVIV 389
           +E    PP +    +   +    S   EE    PPP E+PM PP       PP  +  + 
Sbjct: 550 EESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPL- 608

Query: 390 RKDYDPKASKPLPP-------APAPDEYLVSPITGEKIPASKMQEHMRIGLLDPRWLEQR 442
                P    PL P       +P P++  +SP   E    S M     +  L P  +  R
Sbjct: 609 ---SPPPEESPLSPPPEASRLSPPPEDSPMSPPPEE----SPMSPPPEVSRLSPLPVVSR 661

Query: 443 DRSIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGVEETAIGKKIGEEEIQKPEEKVTW 502
              +     +  +  P  +  +S    A R +       T+            PE+    
Sbjct: 662 ---LSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTS----------PPPEDSPAS 708

Query: 503 DGHSGSMARTQQAAQANITLQEQIEAIHKAKG--LVPE-DDTKEKIGPSKPNEIPQQPPP 559
                S+          + L E+ +   +++G  L P  ++      P +P+  PQ   P
Sbjct: 709 PPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEP 768

Query: 560 PSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVP----VMPRPPMASVVRLPPGSVIA 615
             S        P + +VP  P + P      +S  P    + P+     +  +P    ++
Sbjct: 769 HLSP---QPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLS 825

Query: 616 PMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPP 675
           P P   H         P S  P ++PRP    + +  +  PP++P P   P  P   P P
Sbjct: 826 PQPEESHL-------SPQSEEPCLSPRPEESHL-SPELEKPPLSPRPEKPPEEPGQCPAP 877

Query: 676 ME 677
            E
Sbjct: 878 EE 879



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 39/124 (31%), Positives = 48/124 (38%), Gaps = 20/124 (16%)

Query: 554  PQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRP---PMASVVRLPP 610
            PQ+PPP  +    P S P I    RP +   P      +  P+ PRP   P  S   LPP
Sbjct: 2349 PQEPPPAQALAPSPPSHPDIF---RPGSYTDPY-----AQPPLTPRPQPPPPESCCALPP 2400

Query: 611  GSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAP--PVAPVPAPAPMP 668
             S+  P  P    P       P S     +P  P  +   AF P+P  P    P P   P
Sbjct: 2401 RSL--PSDPFSRVPA-----SPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRP 2453

Query: 669  PVHP 672
            P  P
Sbjct: 2454 PSRP 2457



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 32/103 (31%), Positives = 45/103 (43%), Gaps = 17/103 (16%)

Query: 615  APMPPIIHAPRINVVPMPP---SAPPIMAPRPPPMIV----------PTAFVPAPPVAPV 661
            AP PP  H+   NV  +     SAPP   P PPP  +          P   +P  P+A  
Sbjct: 4885 APEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEP 4944

Query: 662  PAPAPMPPVHPPPPMEDEPTSKKLKT-EDSLMPEEEFLRRNKG 703
            P P+P+P    P     +P ++  +  EDS  P    L++ KG
Sbjct: 4945 PVPSPLPLASSPESARPKPRARPPEEGEDSRPPR---LKKWKG 4984



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 32/100 (32%), Positives = 42/100 (42%), Gaps = 17/100 (17%)

Query: 335  KQEK-AEEPPSQLDQDTQVQDMDEGSDDEEEGQKVPPPPETPMPPPLP------PTPDQV 387
            KQE  A EPP+Q      V ++D         Q   PPPE P PPP P        P + 
Sbjct: 4880 KQESPAPEPPTQHSYTYNVSNLDVR-------QLSAPPPEEPSPPPSPLAPSPASPPTEP 4932

Query: 388  IVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKMQE 427
            +V    +P A    PP P+P     SP +    P ++  E
Sbjct: 4933 LVELPTEPLAE---PPVPSPLPLASSPESARPKPRARPPE 4969



 Score = 40.0 bits (92), Expect = 0.008
 Identities = 149/753 (19%), Positives = 243/753 (32%), Gaps = 108/753 (14%)

Query: 5    PVQAVPPPPPVPTEPKQPTEEE-ASSKEDSAPSKPVVGIIYPPPEVRNIVDKTASFVARN 63
            P +  P  PP  + P  P EE   S  E+S PS  +   + PPPE   +           
Sbjct: 497  PPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSP 556

Query: 64   GPEFEARIRQNEINNPKFNFLNPNDPYHAYYRHKVSEFKEGKAQEPSAAIPKVMQQQQQT 123
             PE            P+ + L+P  P  +       E       E S   P   +     
Sbjct: 557  PPE-----ELPTSPPPEASRLSP-PPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSP 610

Query: 124  TQQQLPQKVQAQVIQETIVPKE----PPPEFEFIADPPSISAFDLDVVKLTAQFVARNGR 179
              ++ P     +  + +  P++    PPPE   ++ PP +S   L  + + ++       
Sbjct: 611  PPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSR--LSPLPVVSRLSPPPEE 668

Query: 180  QFLTQLMQKEQRNYQFDFLRPQHSLFNYFTKLVEQYTKILIPPKGLFSKLKKEAENPREV 239
              L+   ++   +   +  R      +  T    + +    PP+     L  E E+P   
Sbjct: 669  SPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLE-ESPLLP 727

Query: 240  L---DQVCYRVEWAKFQERERKKEEEEKEKERVAYAQIDWHDF----------VVVETVD 286
            L    Q+C R E      R  +     + +E     Q +               V E   
Sbjct: 728  LPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPH 787

Query: 287  FQPNEQGNFPPPTTPEELGARILIQERYEKFGESEEVEMEVESDEEDDKQEKAEEPPSQL 346
              P  +G    P  PEEL              ++EE  +    +E     +  E   S  
Sbjct: 788  LSPQAEGPHLSP-QPEEL----------HLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQ 836

Query: 347  DQDTQVQDMDEGSDDEEEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPA 406
             ++  +    E S    E +K   PP +P P   P  P Q          A + LP  P 
Sbjct: 837  SEEPCLSPRPEESHLSPELEK---PPLSPRPEKPPEEPGQC--------PAPEELPLFPP 885

Query: 407  PDEYLVSPITGE-------KIPASKMQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPG 459
            P E  +SP+ GE       + P S + E + +           + S+  +    +   P 
Sbjct: 886  PGEPSLSPLLGEPALSEPGEPPLSPLPEELPLS-------PSGEPSLSPQLMPPDPLPPP 938

Query: 460  LDIESSLKQLAERRTDIFGVEETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQAN 519
            L     +   A       G  E   G K G+ + + P      +             +AN
Sbjct: 939  L--SPIITAAAPPALSPLGELEYPFGAK-GDSDPESPLAAPILE------TPISPPPEAN 989

Query: 520  ITLQEQIEAIHKAKGLVPEDDTKEKIGPSKP---NEIPQQPPPPSSATNIPSSAPPITSV 576
             T  E +        ++        +GP+ P     +P Q  P    + +P ++PP  S 
Sbjct: 990  CTDPEPVPP------MILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPP--SQ 1041

Query: 577  PRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAP 636
              PP +P  V + +     V+     A +  +    V  P  P +     + +P P    
Sbjct: 1042 CSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDL 1101

Query: 637  PIMAPRPPPMI----------VPTAFVPAPPVAPVPAPAP-------------MPP--VH 671
               AP P P +           P   + AP   P P   P             + P  + 
Sbjct: 1102 SCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLLDPEELA 1161

Query: 672  PPPPMEDEPTSKKLKTEDSLMPEEEFLRRNKGP 704
            P  PME  P  K+   + S   E+E  R    P
Sbjct: 1162 PVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAP 1194



 Score = 38.9 bits (89), Expect = 0.019
 Identities = 39/176 (22%), Positives = 66/176 (37%), Gaps = 29/176 (16%)

Query: 507  GSMARTQQAAQANITLQEQIEAIHKAKGLVPEDDTKEKIGPSKPNEIPQQPPPPSSATNI 566
            G +A+  Q    +   Q+Q++A+   + L       + +  + P + P     P     +
Sbjct: 4203 GVLAKNPQLRHLSPQQQQQLQALLMQRQL----QQSQAVRQTPPYQEPGTQTSPLQG--L 4256

Query: 567  PSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSV-IAPMPPIIHAPR 625
                P +   P P T P       +  +   PRP     +  PPG++   P+   +H   
Sbjct: 4257 LGCQPQLGGFPGPQTGP-------LQELGAGPRPQGPPRLPAPPGALSTGPVLGPVH--- 4306

Query: 626  INVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPT 681
                P PP + P    RP  +  P++         +P  A +PP HP  P    PT
Sbjct: 4307 ----PTPPPSSPQEPKRPSQLPSPSS--------QLPTEAQLPPTHPGTPKPQGPT 4350



 Score = 37.4 bits (85), Expect = 0.055
 Identities = 50/177 (28%), Positives = 70/177 (39%), Gaps = 20/177 (11%)

Query: 510  ARTQQAAQANITLQEQIEAIHKAKGLVPEDDTKEKIGPSKPNEIPQQP-----PPPSSAT 564
            A+  +AA     +Q+Q E+    +  V  D  ++   P+    IP QP     PPP++A 
Sbjct: 2064 AKDNRAAHRINKVQKQAESQINKQTKVG-DIARKTDRPALHLRIPPQPGALGSPPPAAAP 2122

Query: 565  NI---PSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMP--- 618
             I     + P   S      + PP       +VP  P  P    ++LPP  V A +P   
Sbjct: 2123 TIFIGSPTTPAGLSTSADGFLKPPA-----GSVPG-PDSPGELFLKLPP-QVPAQVPSQD 2175

Query: 619  PIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPP 675
            P   AP   + P  P+APP   P P P   P A  P    +  P        H  PP
Sbjct: 2176 PFGLAPAYPLEPRFPTAPPTYPPYPSPTGAP-AQPPMLGASSRPGAGQPGEFHTTPP 2231



 Score = 36.6 bits (83), Expect = 0.094
 Identities = 27/90 (30%), Positives = 33/90 (36%), Gaps = 3/90 (3%)

Query: 556  QPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIA 615
            QPPPP S   +P  + P     R P  P   ++   S  P+ PRP  A      P +   
Sbjct: 2388 QPPPPESCCALPPRSLPSDPFSRVPASP---QSQSSSQSPLTPRPLSAEAFCPSPVTPRF 2444

Query: 616  PMPPIIHAPRINVVPMPPSAPPIMAPRPPP 645
              P     P        P AP    PRP P
Sbjct: 2445 QSPDPYSRPPSRPQSRDPFAPLHKPPRPQP 2474



 Score = 35.4 bits (80), Expect = 0.21
 Identities = 35/134 (26%), Positives = 46/134 (34%), Gaps = 30/134 (22%)

Query: 542  KEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPP 601
            KE++G S P+      PP     + PSS   +  +         ++T  V   P+ PR  
Sbjct: 2289 KEELGASSPS----YGPPNLGFVDSPSSGTHLGGLE--------LKTPDVFKAPLTPRA- 2335

Query: 602  MASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPV 661
             + V    PG  + P  P                PP  A  P P   P  F P     P 
Sbjct: 2336 -SQVEPQSPGLGLRPQEP----------------PPAQALAPSPPSHPDIFRPGSYTDPY 2378

Query: 662  PAPAPMPPVHPPPP 675
              P   P   PPPP
Sbjct: 2379 AQPPLTPRPQPPPP 2392



 Score = 34.7 bits (78), Expect = 0.36
 Identities = 35/113 (30%), Positives = 46/113 (40%), Gaps = 11/113 (9%)

Query: 590 VVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAP-RPPPMIV 648
           V S  P  P P        P G     + P + AP    +P+ P  PP  +P  PPP   
Sbjct: 401 VTSMQPKEPGPLQCEAK--PLGKAGVQLEPQLEAPLNEEMPLLP--PPEESPLSPPPEES 456

Query: 649 PTAFVP-APPVAPVPAPAPMPP----VHPPPPMEDEPTSKKLKTEDSLMPEEE 696
           PT+  P A  ++P P   P  P    +H   P+E+ P S     E  L P  E
Sbjct: 457 PTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPP-PEESPLSPPPE 508



 Score = 33.9 bits (76), Expect = 0.61
 Identities = 33/137 (24%), Positives = 43/137 (31%), Gaps = 1/137 (0%)

Query: 535  LVPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAV 594
            L P   + E   PS      Q P P S   + P S  P   + +PP   PP       ++
Sbjct: 2425 LTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSL 2484

Query: 595  PVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVP 654
                         LP G        +      N V  P +   +  P P     P A   
Sbjct: 2485 AHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGE 2544

Query: 655  APPVAPVPAPAPMPPVH 671
                 PVP P  +PP H
Sbjct: 2545 PSLKPPVPQPG-LPPPH 2560



 Score = 33.9 bits (76), Expect = 0.61
 Identities = 55/245 (22%), Positives = 89/245 (36%), Gaps = 56/245 (22%)

Query: 504  GHSGSMARTQQAAQANITLQEQIEAIHKAKGLVPEDDTKEKIGPSKP-------NEIPQQ 556
            G  GS + ++ ++  ++  Q  +       G  P   T+  +GP +P       N    Q
Sbjct: 4117 GQLGSGSSSEASSVPHLLAQPSVSL-----GDQPGSMTQNLLGPQQPMLERPMQNNTGPQ 4171

Query: 557  PPPPSSATNIPSSAPPITSVP--------------RPPTMP--PPVRTTVVSAVPVMPRP 600
            PP P          P +  +P              + P +    P +   + A+ +  + 
Sbjct: 4172 PPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQL 4231

Query: 601  PMASVVRLPP-----GSVIAPMPPIIHA-PRINVVPMPPSAPPI---MAPRP--PPMIVP 649
              +  VR  P     G+  +P+  ++   P++   P P + P       PRP  PP +  
Sbjct: 4232 QQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRL-- 4289

Query: 650  TAFVPAPPVAPVPAPA--PMPPVHPPPPMEDEP--------TSKKLKTEDSLMPEEEFLR 699
                PAPP A    P   P+ P  PPP    EP         S +L TE  L P      
Sbjct: 4290 ----PAPPGALSTGPVLGPVHPT-PPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTP 4344

Query: 700  RNKGP 704
            + +GP
Sbjct: 4345 KPQGP 4349



 Score = 33.1 bits (74), Expect = 1.0
 Identities = 36/114 (31%), Positives = 42/114 (36%), Gaps = 20/114 (17%)

Query: 577  PRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSAP 636
            P PPT            V  +  PP       PP S +AP P             PP+ P
Sbjct: 4886 PEPPTQHSYTYNVSNLDVRQLSAPPPEEPS--PPPSPLAPSP-----------ASPPTEP 4932

Query: 637  PIMAPRPPPMIVPTAFVPAP-PVAPVPAPA-PMPPVHPPPPMEDE--PTSKKLK 686
             +  P  P    P   VP+P P+A  P  A P P   PP   ED   P  KK K
Sbjct: 4933 LVELPTEPLAEPP---VPSPLPLASSPESARPKPRARPPEEGEDSRPPRLKKWK 4983



 Score = 30.4 bits (67), Expect = 6.7
 Identities = 28/109 (25%), Positives = 45/109 (41%), Gaps = 16/109 (14%)

Query: 333  DDKQEKAEEPPSQLDQDTQVQDMDEGSDDEEEGQKVPPPPE--------TPMPPPLPPTP 384
            D   E+ E P SQ   D    D+ +      EG+   P PE         P  P  P TP
Sbjct: 1809 DGGSERKELPTSQKGDDGP--DIADEESRGLEGKADTPGPEDGGVKASPVPSDPEKPGTP 1866

Query: 385  DQVIVRKDYDPKASKPLPPAPAPD-EYLVSPITGEKIPASKMQEHMRIG 432
             + ++  D D  +++ LP   + D + L   + G     S+ ++H+  G
Sbjct: 1867 GEGMLSSDLDRISTEELPKMESKDLQQLFKDVLG-----SEREQHLGCG 1910



 Score = 30.4 bits (67), Expect = 6.7
 Identities = 21/53 (39%), Positives = 26/53 (49%), Gaps = 6/53 (11%)

Query: 547  PSKPNEI--PQQPPPPSSATNIPSSAPPI---TSVPRPPTM-PPPVRTTVVSA 593
            PS P E   P Q P PSS     +  PP    T  P+ PT+ PPP R +  +A
Sbjct: 4311 PSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAA 4363



 Score = 30.0 bits (66), Expect = 8.8
 Identities = 15/38 (39%), Positives = 16/38 (42%)

Query: 370  PPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAP 407
            PPP   + P  P  PD        DP A  PL P P P
Sbjct: 2352 PPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQP 2389


>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
          Length = 464

 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 53/153 (34%), Positives = 61/153 (39%), Gaps = 27/153 (17%)

Query: 534 GLVPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSA 593
           GL P     E + P  P  +P  P PP        + P  +  P PP +PPP       A
Sbjct: 240 GLPPRPPLPESLPPPPPGGLPLPPMPP--------TGPAPSGPPGPPQLPPP-------A 284

Query: 594 VPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVPMPPSA-PPIMAPRPPPMIVPTAF 652
             V P  P+      PP S + P  P +H P   V P  P   PP     PP    P   
Sbjct: 285 PGVHPPAPVVH----PPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVHPP---APGVH 337

Query: 653 VPAPPVAPVPAPA---PMPPVHPPPPMEDEPTS 682
            PAP V P PAP    P P VHPP P    P S
Sbjct: 338 PPAPGVHP-PAPGVHPPAPGVHPPAPGVHPPPS 369



 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 51/148 (34%), Positives = 63/148 (42%), Gaps = 26/148 (17%)

Query: 549 KPNEIPQQPPPPSSATNIPSSAPPITS--VPRPP---TMPPPVRTTVVSAVPVMPRPPMA 603
           K  + P  P  P+    +    PP+ +   PRPP   ++PPP        +P+ P PP  
Sbjct: 213 KMEKPPAPPSLPAGPPGVKRPPPPLMNGLPPRPPLPESLPPPPP----GGLPLPPMPPTG 268

Query: 604 SVVRLPPGSVIAPMP--------PIIHAPRINVVPMPPSA-PPIMAPRPPPMIV--PTAF 652
                PPG    P P        P++H P   V P  P   PP     PP   V  PT+ 
Sbjct: 269 PAPSGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSG 328

Query: 653 V--PAPPVAPVPAPA---PMPPVHPPPP 675
           V  PAP V P PAP    P P VHPP P
Sbjct: 329 VHPPAPGVHP-PAPGVHPPAPGVHPPAP 355



 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 38/126 (30%), Positives = 45/126 (35%), Gaps = 16/126 (12%)

Query: 557 PPPPSSATNIPSSAPPITSVPRPPT-----MPPPVRTTVVSAVPVMP--RPPMASVVRLP 609
           PP P      P   PP   V  PP+       P V     +  P  P   PP   +    
Sbjct: 345 PPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQA 404

Query: 610 PGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPP 669
           PG  + P PP +H     V P PP   P      PP        P PP+   P P+  P 
Sbjct: 405 PG--VHPQPPGVHPSAPGVHPQPPGVHPSNPGVHPP-------TPMPPMLRPPLPSEGPG 455

Query: 670 VHPPPP 675
             PPPP
Sbjct: 456 NIPPPP 461



 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 34/96 (35%), Positives = 43/96 (44%), Gaps = 20/96 (20%)

Query: 597 MPRPPMASVVRLPPGSVIAPMPPIIHA--PRINVVPMPPSAPPIMAPRPPPMIVPTAFVP 654
           M +PP    +   P  V  P PP+++   PR    P+P S PP     PPP  +P    P
Sbjct: 214 MEKPPAPPSLPAGPPGVKRPPPPLMNGLPPR---PPLPESLPP-----PPPGGLPLP--P 263

Query: 655 APPVAPVPA--------PAPMPPVHPPPPMEDEPTS 682
            PP  P P+        P P P VHPP P+   P S
Sbjct: 264 MPPTGPAPSGPPGPPQLPPPAPGVHPPAPVVHPPAS 299



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 49/153 (32%), Positives = 61/153 (39%), Gaps = 23/153 (15%)

Query: 545 IGPSKPNEIPQQPP--PPSSATNIPSSA--PPITSV-PRPPTMPPPVRTTVVSAVPVMPR 599
           + P  P   P  P   PP+S  + P+    PP   V P  P + PP       A  V P 
Sbjct: 308 VHPPAPGVHPPAPGVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHP- 366

Query: 600 PPMASVVRLPPG-----SVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTA--F 652
           PP A V    PG       + P  P +H P   + P  P   P      PP + P+A   
Sbjct: 367 PPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHP-----QPPGVHPSAPGV 421

Query: 653 VPAPP-VAP----VPAPAPMPPVHPPPPMEDEP 680
            P PP V P    V  P PMPP+  PP   + P
Sbjct: 422 HPQPPGVHPSNPGVHPPTPMPPMLRPPLPSEGP 454



 Score = 37.0 bits (84), Expect = 0.072
 Identities = 54/246 (21%), Positives = 78/246 (31%), Gaps = 21/246 (8%)

Query: 365 GQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASK 424
           G K PPPP     PP PP P+ +       P    PLPP P        P    ++P   
Sbjct: 229 GVKRPPPPLMNGLPPRPPLPESL----PPPPPGGLPLPPMPPTGPAPSGPPGPPQLPPPA 284

Query: 425 MQEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAERRTDIF----GVE 480
              H    ++ P        +         V+ P   +      +      +     GV 
Sbjct: 285 PGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVHPPAPGVHPPAPGVH 344

Query: 481 ETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIH-KAKGLVPED 539
             A G       +  P   V     +G   +      A   +  Q   +H  A G+ P+ 
Sbjct: 345 PPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQ- 403

Query: 540 DTKEKIGPSKPNEIPQ----QPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVP 595
                + P  P   P      P PP    + P   PP    P PP + PP+ +     +P
Sbjct: 404 --APGVHPQPPGVHPSAPGVHPQPPGVHPSNPGVHPP---TPMPPMLRPPLPSEGPGNIP 458

Query: 596 VMPRPP 601
             P PP
Sbjct: 459 --PPPP 462


>gi|7706501 WW domain binding protein 11 [Homo sapiens]
          Length = 641

 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 91/355 (25%), Positives = 125/355 (35%), Gaps = 72/355 (20%)

Query: 367 KVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKMQ 426
           ++PP  + P PPP PP P QV+         +  LPP    ++ L SP   ++     + 
Sbjct: 192 RLPPGRKPPGPPPGPPPP-QVVQMYGRKVGFALDLPPRRRDEDMLYSPELAQRGHDDDVS 250

Query: 427 EHMRIGLLDPRWLEQRDRSIREKQSDD--------------------------EVYAPGL 460
                   D  + E  D+   +  +DD                          E    GL
Sbjct: 251 STSE----DDGYPEDMDQDKHDDSTDDSDTDKSDGESDGDEFVHRDNGERDNNEEKKSGL 306

Query: 461 DIESS--------LKQLAERRTDIFGVEETAIGKKIGEE--EIQKPEEKVTWDGHSGSMA 510
            +  +         K+  +  T +  +     G++I EE  E+++  E    D    S A
Sbjct: 307 SVRFADMPGKSRKKKKNMKELTPLQAMMLRMAGQEIPEEGREVEEFSEDDDEDDSDDSEA 366

Query: 511 RTQQAAQANITLQEQIEAIHKAKGLVPEDDTKEKIGPSKPNEIP----QQPPPPSSATNI 566
             Q   Q            HK +       T      + P  +P    Q PP P      
Sbjct: 367 EKQSQKQ------------HKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLG 414

Query: 567 PSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRI 626
           P  APP+   P PPT  PP         P   RPP    +R P   ++ P PP    P  
Sbjct: 415 PPPAPPLRP-PGPPTGLPPGPPP---GAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGP 470

Query: 627 NVVPMPPSAPPIMAPR-PPPMIVPTAFVPAPPVAPVPAPAPM-----PPVHPPPP 675
              P PP  PP   PR PPP + P    PAPP  P P P  M     PP+ P PP
Sbjct: 471 PPGP-PPGLPPGPPPRGPPPRLPP----PAPPGIPPPRPGMMRPPLVPPLGPAPP 520



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 36/117 (30%), Positives = 45/117 (38%), Gaps = 16/117 (13%)

Query: 547 PSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVV 606
           P +P   P  PPP       P   PP    P PP +PPP         P M RPP+    
Sbjct: 464 PGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPR--------PGMMRPPL---- 511

Query: 607 RLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPA 663
            +PP   + P PP +  P     P   SAPP +  RP       A +     A + A
Sbjct: 512 -VPP---LGPAPPGLFPPAPLPNPGVLSAPPNLIQRPKADDTSAATIEKKATATISA 564



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 39/156 (25%), Positives = 58/156 (37%), Gaps = 15/156 (9%)

Query: 256 ERKKEEEEKEKERVAYAQIDWHDFVVVETVDFQPNEQGNFPPPTTPEELGARILIQERYE 315
           ER   EE+K    V +A +                ++ N    T  + +  R+  QE  E
Sbjct: 295 ERDNNEEKKSGLSVRFADMPGKS----------RKKKKNMKELTPLQAMMLRMAGQEIPE 344

Query: 316 KFGESEEVEMEVESDEEDDKQEKAEEPPSQLDQDTQVQDMDEGSDDEEEGQKVPP----P 371
           +  E EE   + + D+ DD + + +      ++          S  +   Q VPP     
Sbjct: 345 EGREVEEFSEDDDEDDSDDSEAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQA 404

Query: 372 PETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAP 407
           P  P PPPL P P   + R    P    P PP  AP
Sbjct: 405 PPMPGPPPLGPPPAPPL-RPPGPPTGLPPGPPPGAP 439



 Score = 40.0 bits (92), Expect = 0.008
 Identities = 30/103 (29%), Positives = 40/103 (38%), Gaps = 9/103 (8%)

Query: 319 ESEEVEMEVESDEEDDKQEKAEEPPSQLDQDTQVQDMDEGSDDEEEGQKVPP---PPET- 374
           E  EVE   E D+EDD  +   E  SQ  +  + +   +G+      Q+ PP   PP   
Sbjct: 345 EGREVEEFSEDDDEDDSDDSEAEKQSQ--KQHKEESHSDGTSTASSQQQAPPQSVPPSQI 402

Query: 375 ---PMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSP 414
              PMP P P  P      +   P    P  P P    +L  P
Sbjct: 403 QAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPP 445



 Score = 34.7 bits (78), Expect = 0.36
 Identities = 23/80 (28%), Positives = 34/80 (42%), Gaps = 10/80 (12%)

Query: 616 PMPPIIHAPR---INVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPV-------APVPAPA 665
           P+P + HAP    I  +P+P + PP +  +      PT  V   P+        P     
Sbjct: 140 PLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKP 199

Query: 666 PMPPVHPPPPMEDEPTSKKL 685
           P PP  PPPP   +   +K+
Sbjct: 200 PGPPPGPPPPQVVQMYGRKV 219


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.132    0.386 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,755,315
Number of Sequences: 37866
Number of extensions: 2966166
Number of successful extensions: 71758
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 802
Number of HSP's successfully gapped in prelim test: 1685
Number of HSP's that attempted gapping in prelim test: 23434
Number of HSP's gapped (non-prelim): 27872
length of query: 793
length of database: 18,247,518
effective HSP length: 110
effective length of query: 683
effective length of database: 14,082,258
effective search space: 9618182214
effective search space used: 9618182214
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press