Guide to the Human Genome
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Search of human proteins with 49574546

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|49574546 runt-related transcription factor 1 isoform AML1b
[Homo sapiens]
         (453 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|49574546 runt-related transcription factor 1 isoform AML1b [H...   920   0.0  
gi|19923198 runt-related transcription factor 1 isoform AML1c [H...   911   0.0  
gi|226442791 runt-related transcription factor 2 isoform b [Homo...   577   e-165
gi|66934969 runt-related transcription factor 2 isoform c [Homo ...   575   e-164
gi|226442783 runt-related transcription factor 2 isoform a [Homo...   565   e-161
gi|169790837 runt-related transcription factor 1 isoform AML1a [...   488   e-138
gi|4757918 runt-related transcription factor 3 isoform 2 [Homo s...   486   e-137
gi|72534652 runt-related transcription factor 3 isoform 1 [Homo ...   476   e-134
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]     50   3e-06
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]     50   3e-06
gi|28558973 mediator complex subunit 14 [Homo sapiens]                 46   6e-05
gi|21536357 TBP-associated factor 6 isoform delta [Homo sapiens]       42   0.001
gi|5032147 TBP-associated factor 6 isoform alpha [Homo sapiens]        42   0.001
gi|21536359 TBP-associated factor 6 isoform alpha [Homo sapiens]       42   0.001
gi|56549666 tyrosine kinase, non-receptor, 2 isoform 1 [Homo sap...    41   0.003
gi|58331191 tyrosine kinase, non-receptor, 2 isoform 2 [Homo sap...    41   0.003
gi|55750053 atrophin-1 [Homo sapiens]                                  41   0.003
gi|55750041 atrophin-1 [Homo sapiens]                                  41   0.003
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]             40   0.003
gi|56549668 AT rich interactive domain 2 (ARID, RFX-like) [Homo ...    39   0.010
gi|22027471 neuronal PAS domain protein 2 [Homo sapiens]               39   0.013
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    39   0.013
gi|116284392 mucin 2 precursor [Homo sapiens]                          38   0.017
gi|5454064 RNA binding motif protein 14 [Homo sapiens]                 38   0.017
gi|21536355 TBP-associated factor 6 isoform gamma [Homo sapiens]       37   0.028
gi|32171215 CREB regulated transcription coactivator 2 [Homo sap...    37   0.028
gi|45827755 transforming, acidic coiled-coil containing protein ...    37   0.028
gi|13376611 zinc finger protein 703 [Homo sapiens]                     37   0.037
gi|193083129 MAP/microtubule affinity-regulating kinase 3 isofor...    37   0.037
gi|46852166 MAP/microtubule affinity-regulating kinase 3 isoform...    37   0.037

>gi|49574546 runt-related transcription factor 1 isoform AML1b [Homo
           sapiens]
          Length = 453

 Score =  920 bits (2379), Expect = 0.0
 Identities = 453/453 (100%), Positives = 453/453 (100%)

Query: 1   MRIPVDASTSRRFTPPSTALSPGKMSEALPLGAPDAGAALAGKLRSGDRSMVEVLADHPG 60
           MRIPVDASTSRRFTPPSTALSPGKMSEALPLGAPDAGAALAGKLRSGDRSMVEVLADHPG
Sbjct: 1   MRIPVDASTSRRFTPPSTALSPGKMSEALPLGAPDAGAALAGKLRSGDRSMVEVLADHPG 60

Query: 61  ELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALGDVPDGTLVTVMAGNDENYSAELRNA 120
           ELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALGDVPDGTLVTVMAGNDENYSAELRNA
Sbjct: 61  ELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALGDVPDGTLVTVMAGNDENYSAELRNA 120

Query: 121 TAAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKITVDGPREPRRHR 180
           TAAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKITVDGPREPRRHR
Sbjct: 121 TAAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKITVDGPREPRRHR 180

Query: 181 QKLDDQTKPGSLSFSERLSELEQLRRTAMRVSPHHPAPTPNPRASLNHSTAFNPQPQSQM 240
           QKLDDQTKPGSLSFSERLSELEQLRRTAMRVSPHHPAPTPNPRASLNHSTAFNPQPQSQM
Sbjct: 181 QKLDDQTKPGSLSFSERLSELEQLRRTAMRVSPHHPAPTPNPRASLNHSTAFNPQPQSQM 240

Query: 241 QDTRQIQPSPPWSYDQSYQYLGSIASPSVHPATPISPGRASGMTTLSAELSSRLSTAPDL 300
           QDTRQIQPSPPWSYDQSYQYLGSIASPSVHPATPISPGRASGMTTLSAELSSRLSTAPDL
Sbjct: 241 QDTRQIQPSPPWSYDQSYQYLGSIASPSVHPATPISPGRASGMTTLSAELSSRLSTAPDL 300

Query: 301 TAFSDPRQFPALPSISDPRMHYPGAFTYSPTPVTSGIGIGMSAMGSATRYHTYLPPPYPG 360
           TAFSDPRQFPALPSISDPRMHYPGAFTYSPTPVTSGIGIGMSAMGSATRYHTYLPPPYPG
Sbjct: 301 TAFSDPRQFPALPSISDPRMHYPGAFTYSPTPVTSGIGIGMSAMGSATRYHTYLPPPYPG 360

Query: 361 SSQAQGGPFQASSPSYHLYYGASAGSYQFSMVGGERSPPRILPPCTNASTGSALLNPSLP 420
           SSQAQGGPFQASSPSYHLYYGASAGSYQFSMVGGERSPPRILPPCTNASTGSALLNPSLP
Sbjct: 361 SSQAQGGPFQASSPSYHLYYGASAGSYQFSMVGGERSPPRILPPCTNASTGSALLNPSLP 420

Query: 421 NQSDVVEAEGSHSNSPTNMAPSARLEEAVWRPY 453
           NQSDVVEAEGSHSNSPTNMAPSARLEEAVWRPY
Sbjct: 421 NQSDVVEAEGSHSNSPTNMAPSARLEEAVWRPY 453


>gi|19923198 runt-related transcription factor 1 isoform AML1c [Homo
           sapiens]
          Length = 480

 Score =  911 bits (2354), Expect = 0.0
 Identities = 448/448 (100%), Positives = 448/448 (100%)

Query: 6   DASTSRRFTPPSTALSPGKMSEALPLGAPDAGAALAGKLRSGDRSMVEVLADHPGELVRT 65
           DASTSRRFTPPSTALSPGKMSEALPLGAPDAGAALAGKLRSGDRSMVEVLADHPGELVRT
Sbjct: 33  DASTSRRFTPPSTALSPGKMSEALPLGAPDAGAALAGKLRSGDRSMVEVLADHPGELVRT 92

Query: 66  DSPNFLCSVLPTHWRCNKTLPIAFKVVALGDVPDGTLVTVMAGNDENYSAELRNATAAMK 125
           DSPNFLCSVLPTHWRCNKTLPIAFKVVALGDVPDGTLVTVMAGNDENYSAELRNATAAMK
Sbjct: 93  DSPNFLCSVLPTHWRCNKTLPIAFKVVALGDVPDGTLVTVMAGNDENYSAELRNATAAMK 152

Query: 126 NQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKITVDGPREPRRHRQKLDD 185
           NQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKITVDGPREPRRHRQKLDD
Sbjct: 153 NQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKITVDGPREPRRHRQKLDD 212

Query: 186 QTKPGSLSFSERLSELEQLRRTAMRVSPHHPAPTPNPRASLNHSTAFNPQPQSQMQDTRQ 245
           QTKPGSLSFSERLSELEQLRRTAMRVSPHHPAPTPNPRASLNHSTAFNPQPQSQMQDTRQ
Sbjct: 213 QTKPGSLSFSERLSELEQLRRTAMRVSPHHPAPTPNPRASLNHSTAFNPQPQSQMQDTRQ 272

Query: 246 IQPSPPWSYDQSYQYLGSIASPSVHPATPISPGRASGMTTLSAELSSRLSTAPDLTAFSD 305
           IQPSPPWSYDQSYQYLGSIASPSVHPATPISPGRASGMTTLSAELSSRLSTAPDLTAFSD
Sbjct: 273 IQPSPPWSYDQSYQYLGSIASPSVHPATPISPGRASGMTTLSAELSSRLSTAPDLTAFSD 332

Query: 306 PRQFPALPSISDPRMHYPGAFTYSPTPVTSGIGIGMSAMGSATRYHTYLPPPYPGSSQAQ 365
           PRQFPALPSISDPRMHYPGAFTYSPTPVTSGIGIGMSAMGSATRYHTYLPPPYPGSSQAQ
Sbjct: 333 PRQFPALPSISDPRMHYPGAFTYSPTPVTSGIGIGMSAMGSATRYHTYLPPPYPGSSQAQ 392

Query: 366 GGPFQASSPSYHLYYGASAGSYQFSMVGGERSPPRILPPCTNASTGSALLNPSLPNQSDV 425
           GGPFQASSPSYHLYYGASAGSYQFSMVGGERSPPRILPPCTNASTGSALLNPSLPNQSDV
Sbjct: 393 GGPFQASSPSYHLYYGASAGSYQFSMVGGERSPPRILPPCTNASTGSALLNPSLPNQSDV 452

Query: 426 VEAEGSHSNSPTNMAPSARLEEAVWRPY 453
           VEAEGSHSNSPTNMAPSARLEEAVWRPY
Sbjct: 453 VEAEGSHSNSPTNMAPSARLEEAVWRPY 480


>gi|226442791 runt-related transcription factor 2 isoform b [Homo
           sapiens]
          Length = 499

 Score =  577 bits (1488), Expect = e-165
 Identities = 307/493 (62%), Positives = 363/493 (73%), Gaps = 58/493 (11%)

Query: 6   DASTSRRFTPPSTALSPGKMSEALPL---------------------------------- 31
           D STSRRF+PPS++L PGKMS+  P+                                  
Sbjct: 20  DPSTSRRFSPPSSSLQPGKMSDVSPVVAAQQQQQQQQQQQQQQQQQQQQQQQEAAAAAAA 79

Query: 32  -GAPDAGAALAGKLRS--GDRSMVEVLADHPGELVRTDSPNFLCSVLPTHWRCNKTLPIA 88
             A  A AA   +LR    +R+MVE++ADHP ELVRTDSPNFLCSVLP+HWRCNKTLP+A
Sbjct: 80  AAAAAAAAAAVPRLRPPHDNRTMVEIIADHPAELVRTDSPNFLCSVLPSHWRCNKTLPVA 139

Query: 89  FKVVALGDVPDGTLVTVMAGNDENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTL 148
           FKVVALG+VPDGT+VTVMAGNDENYSAELRNA+A MKNQVARFNDLRFVGRSGRGKSFTL
Sbjct: 140 FKVVALGEVPDGTVVTVMAGNDENYSAELRNASAVMKNQVARFNDLRFVGRSGRGKSFTL 199

Query: 149 TITVFTNPPQVATYHRAIKITVDGPREPRRHRQKLDDQTKPGSLSFSERLSELEQLRRTA 208
           TITVFTNPPQVATYHRAIK+TVDGPREPRRHRQKLDD +KP    FS+RLS+L ++   +
Sbjct: 200 TITVFTNPPQVATYHRAIKVTVDGPREPRRHRQKLDD-SKPS--LFSDRLSDLGRIPHPS 256

Query: 209 MRVSPHHPAPTPNPRASLNHS-TAFNPQPQSQMQDTRQIQPSPPWSYDQSY-QYLGSIAS 266
           MRV      P  NPR SLN + + FNPQ QSQ+ D RQ Q SPPWSYDQSY  YL  + S
Sbjct: 257 MRVG----VPPQNPRPSLNSAPSPFNPQGQSQITDPRQAQSSPPWSYDQSYPSYLSQMTS 312

Query: 267 PSVHPATPISPGRASGMTTLSAELSSRLSTAPDLTAFSDPRQFPALPSI-----SDPRMH 321
           PS+H  TP+S  R +G+  ++ ++  R+S A +L  FSDPRQFP++ S+     S+PRMH
Sbjct: 313 PSIHSTTPLSSTRGTGLPAIT-DVPRRISGASELGPFSDPRQFPSISSLTESRFSNPRMH 371

Query: 322 YPGAFTYSPTPVTSGIGIGMSAMGSATRYHTYLPPPYPGSSQAQGGPFQASSPSYHLYYG 381
           YP  FTY+P PVTSG+ +GMSA    T YHTYLPPPYPGSSQ+Q GPFQ SS  Y LYYG
Sbjct: 372 YPATFTYTP-PVTSGMSLGMSA---TTHYHTYLPPPYPGSSQSQSGPFQTSSTPY-LYYG 426

Query: 382 ASAGSYQFSMV-GGERSPPRILPPCTNASTGSALLNPSLPNQSDVVEAEGSHSNSPTNMA 440
            S+GSYQF MV GG+RSP R+LPPCT  S GS LLNP+LPNQ+D V+A+GSHS+SPT + 
Sbjct: 427 TSSGSYQFPMVPGGDRSPSRMLPPCTTTSNGSTLLNPNLPNQNDGVDADGSHSSSPTVLN 486

Query: 441 PSARLEEAVWRPY 453
            S R++E+VWRPY
Sbjct: 487 SSGRMDESVWRPY 499


>gi|66934969 runt-related transcription factor 2 isoform c [Homo
           sapiens]
          Length = 507

 Score =  575 bits (1481), Expect = e-164
 Identities = 312/520 (60%), Positives = 368/520 (70%), Gaps = 80/520 (15%)

Query: 1   MRIPVDASTSRRFTPPSTALSPGKMSEALPL----------------------------- 31
           MRIPVD STSRRF+PPS++L PGKMS+  P+                             
Sbjct: 1   MRIPVDPSTSRRFSPPSSSLQPGKMSDVSPVVAAQQQQQQQQQQQQQQQQQQQQQQQEAA 60

Query: 32  ------GAPDAGAALAGKLRS--GDRSMVEVLADHPGELVRTDSPNFLCSVLPTHWRCNK 83
                  A  A AA   +LR    +R+MVE++ADHP ELVRTDSPNFLCSVLP+HWRCNK
Sbjct: 61  AAAAAAAAAAAAAAAVPRLRPPHDNRTMVEIIADHPAELVRTDSPNFLCSVLPSHWRCNK 120

Query: 84  TLPIAFKVVALGDVPDGTLVTVMAGNDENYSAELRNATAAMKNQVARFNDLRFVGRSGRG 143
           TLP+AFKVVALG+VPDGT+VTVMAGNDENYSAELRNA+A MKNQVARFNDLRFVGRSGRG
Sbjct: 121 TLPVAFKVVALGEVPDGTVVTVMAGNDENYSAELRNASAVMKNQVARFNDLRFVGRSGRG 180

Query: 144 KSFTLTITVFTNPPQVATYHRAIKITVDGPREPRRHRQKLDDQTKPGSLSFSERLSELEQ 203
           KSFTLTITVFTNPPQVATYHRAIK+TVDGPREPRRHRQKLDD +KP    FS+RLS+L +
Sbjct: 181 KSFTLTITVFTNPPQVATYHRAIKVTVDGPREPRRHRQKLDD-SKPS--LFSDRLSDLGR 237

Query: 204 LRRTAMRVSPHHPAPTPNPRASLNHS-TAFNPQPQSQMQDTRQIQPSPPWSYDQSY-QYL 261
           +   +MRV      P  NPR SLN + + FNPQ QSQ+ D RQ Q SPPWSYDQSY  YL
Sbjct: 238 IPHPSMRVG----VPPQNPRPSLNSAPSPFNPQGQSQITDPRQAQSSPPWSYDQSYPSYL 293

Query: 262 GSIASPSVHPATPISPGRASGMTTLSAELSSRLST----------------------APD 299
             + SPS+H  TP+S  R +G+  ++ ++  R+S                       A +
Sbjct: 294 SQMTSPSIHSTTPLSSTRGTGLPAIT-DVPRRISDDDTATSDFCLWPSTLSKKSQAGASE 352

Query: 300 LTAFSDPRQFPALPSI-----SDPRMHYPGAFTYSPTPVTSGIGIGMSAMGSATRYHTYL 354
           L  FSDPRQFP++ S+     S+PRMHYP  FTY+P PVTSG+ +GMSA    T YHTYL
Sbjct: 353 LGPFSDPRQFPSISSLTESRFSNPRMHYPATFTYTP-PVTSGMSLGMSA---TTHYHTYL 408

Query: 355 PPPYPGSSQAQGGPFQASSPSYHLYYGASAGSYQFSMV-GGERSPPRILPPCTNASTGSA 413
           PPPYPGSSQ+Q GPFQ SS  Y LYYG S+GSYQF MV GG+RSP R+LPPCT  S GS 
Sbjct: 409 PPPYPGSSQSQSGPFQTSSTPY-LYYGTSSGSYQFPMVPGGDRSPSRMLPPCTTTSNGST 467

Query: 414 LLNPSLPNQSDVVEAEGSHSNSPTNMAPSARLEEAVWRPY 453
           LLNP+LPNQ+D V+A+GSHS+SPT +  S R++E+VWRPY
Sbjct: 468 LLNPNLPNQNDGVDADGSHSSSPTVLNSSGRMDESVWRPY 507


>gi|226442783 runt-related transcription factor 2 isoform a [Homo
           sapiens]
          Length = 521

 Score =  565 bits (1456), Expect = e-161
 Identities = 307/515 (59%), Positives = 363/515 (70%), Gaps = 80/515 (15%)

Query: 6   DASTSRRFTPPSTALSPGKMSEALPL---------------------------------- 31
           D STSRRF+PPS++L PGKMS+  P+                                  
Sbjct: 20  DPSTSRRFSPPSSSLQPGKMSDVSPVVAAQQQQQQQQQQQQQQQQQQQQQQQEAAAAAAA 79

Query: 32  -GAPDAGAALAGKLRS--GDRSMVEVLADHPGELVRTDSPNFLCSVLPTHWRCNKTLPIA 88
             A  A AA   +LR    +R+MVE++ADHP ELVRTDSPNFLCSVLP+HWRCNKTLP+A
Sbjct: 80  AAAAAAAAAAVPRLRPPHDNRTMVEIIADHPAELVRTDSPNFLCSVLPSHWRCNKTLPVA 139

Query: 89  FKVVALGDVPDGTLVTVMAGNDENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTL 148
           FKVVALG+VPDGT+VTVMAGNDENYSAELRNA+A MKNQVARFNDLRFVGRSGRGKSFTL
Sbjct: 140 FKVVALGEVPDGTVVTVMAGNDENYSAELRNASAVMKNQVARFNDLRFVGRSGRGKSFTL 199

Query: 149 TITVFTNPPQVATYHRAIKITVDGPREPRRHRQKLDDQTKPGSLSFSERLSELEQLRRTA 208
           TITVFTNPPQVATYHRAIK+TVDGPREPRRHRQKLDD +KP    FS+RLS+L ++   +
Sbjct: 200 TITVFTNPPQVATYHRAIKVTVDGPREPRRHRQKLDD-SKPS--LFSDRLSDLGRIPHPS 256

Query: 209 MRVSPHHPAPTPNPRASLNHS-TAFNPQPQSQMQDTRQIQPSPPWSYDQSY-QYLGSIAS 266
           MRV      P  NPR SLN + + FNPQ QSQ+ D RQ Q SPPWSYDQSY  YL  + S
Sbjct: 257 MRVG----VPPQNPRPSLNSAPSPFNPQGQSQITDPRQAQSSPPWSYDQSYPSYLSQMTS 312

Query: 267 PSVHPATPISPGRASGMTTLSAELSSRLST----------------------APDLTAFS 304
           PS+H  TP+S  R +G+  ++ ++  R+S                       A +L  FS
Sbjct: 313 PSIHSTTPLSSTRGTGLPAIT-DVPRRISDDDTATSDFCLWPSTLSKKSQAGASELGPFS 371

Query: 305 DPRQFPALPSI-----SDPRMHYPGAFTYSPTPVTSGIGIGMSAMGSATRYHTYLPPPYP 359
           DPRQFP++ S+     S+PRMHYP  FTY+P PVTSG+ +GMSA    T YHTYLPPPYP
Sbjct: 372 DPRQFPSISSLTESRFSNPRMHYPATFTYTP-PVTSGMSLGMSA---TTHYHTYLPPPYP 427

Query: 360 GSSQAQGGPFQASSPSYHLYYGASAGSYQFSMV-GGERSPPRILPPCTNASTGSALLNPS 418
           GSSQ+Q GPFQ SS  Y LYYG S+GSYQF MV GG+RSP R+LPPCT  S GS LLNP+
Sbjct: 428 GSSQSQSGPFQTSSTPY-LYYGTSSGSYQFPMVPGGDRSPSRMLPPCTTTSNGSTLLNPN 486

Query: 419 LPNQSDVVEAEGSHSNSPTNMAPSARLEEAVWRPY 453
           LPNQ+D V+A+GSHS+SPT +  S R++E+VWRPY
Sbjct: 487 LPNQNDGVDADGSHSSSPTVLNSSGRMDESVWRPY 521


>gi|169790837 runt-related transcription factor 1 isoform AML1a
           [Homo sapiens]
          Length = 250

 Score =  488 bits (1257), Expect = e-138
 Identities = 243/252 (96%), Positives = 246/252 (97%), Gaps = 4/252 (1%)

Query: 1   MRIPVDASTSRRFTPPSTALSPGKMSEALPLGAPDAGAALAGKLRSGDRSMVEVLADHPG 60
           MRIPVDASTSRRFTPPSTALSPGKMSEALPLGAPDAGAALAGKLRSGDRSMVEVLADHPG
Sbjct: 1   MRIPVDASTSRRFTPPSTALSPGKMSEALPLGAPDAGAALAGKLRSGDRSMVEVLADHPG 60

Query: 61  ELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALGDVPDGTLVTVMAGNDENYSAELRNA 120
           ELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALGDVPDGTLVTVMAGNDENYSAELRNA
Sbjct: 61  ELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALGDVPDGTLVTVMAGNDENYSAELRNA 120

Query: 121 TAAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKITVDGPREPRRHR 180
           TAAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKITVDGPREPRRHR
Sbjct: 121 TAAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKITVDGPREPRRHR 180

Query: 181 QKLDDQTKPGSLSFSERLSELEQLRRTAMRVSPHHPAPTPNPRASLNHSTAFNPQPQSQM 240
           QKLDDQTKPGSLSFSERLSELEQLRRTAMRVSPHHPAPTPNPRASLNHSTAFNPQPQSQM
Sbjct: 181 QKLDDQTKPGSLSFSERLSELEQLRRTAMRVSPHHPAPTPNPRASLNHSTAFNPQPQSQM 240

Query: 241 QDTRQIQPSPPW 252
           Q+    + + PW
Sbjct: 241 QE----EDTAPW 248


>gi|4757918 runt-related transcription factor 3 isoform 2 [Homo
           sapiens]
          Length = 415

 Score =  486 bits (1251), Expect = e-137
 Identities = 275/472 (58%), Positives = 321/472 (68%), Gaps = 76/472 (16%)

Query: 1   MRIPVDASTSRRFTPPSTAL----SPGKMSEALPLGAPDAGAALAGKLRSGDRSMVEVLA 56
           MRIPVD STSRRFTPPS A       GKM E     +  A     G+ R   RSMV+VLA
Sbjct: 1   MRIPVDPSTSRRFTPPSPAFPCGGGGGKMGENSGALSAQAAVGPGGRARPEVRSMVDVLA 60

Query: 57  DHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALGDVPDGTLVTVMAGNDENYSAE 116
           DH GELVRTDSPNFLCSVLP+HWRCNKTLP+AFKVVALGDVPDGT+VTVMAGNDENYSAE
Sbjct: 61  DHAGELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGDVPDGTVVTVMAGNDENYSAE 120

Query: 117 LRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKITVDGPREP 176
           LRNA+A MKNQVARFNDLRFVGRSGRGKSFTLTITVFTNP QVATYHRAIK+TVDGPREP
Sbjct: 121 LRNASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPTQVATYHRAIKVTVDGPREP 180

Query: 177 RRHRQKLDDQTKPGSLSFSERLSELEQLRRTAMRVSPHHPAPTPNPRASLNHSTAFNPQP 236
           RRHRQKL+DQTKP    F +R  +LE+LR   MRV+P     TP+PR SL+ ++ F+ QP
Sbjct: 181 RRHRQKLEDQTKP----FPDRFGDLERLR---MRVTP----STPSPRGSLSTTSHFSSQP 229

Query: 237 QSQMQDTRQIQP-SPPWSYDQSYQYLGSIASPSVHPATPISPGRASGMTTLSAELSSRLS 295
           Q+ +Q T ++ P S P  +D+S+                                     
Sbjct: 230 QTPIQGTSELNPFSDPRQFDRSF------------------------------------P 253

Query: 296 TAPDLTAFSDPRQFPALPSISDPRMHYPG----AFTYSPTPV-TSGIGIGMSAMGSATRY 350
           T P LT      +FP      DPRMHYPG    AF YS TP  TS   + ++ M + +R+
Sbjct: 254 TLPTLT----ESRFP------DPRMHYPGAMSAAFPYSATPSGTSISSLSVAGMPATSRF 303

Query: 351 -HTYLPPPYPGSSQAQGGPFQASSPSYHLYYGASAGSYQFSMV-----GGERSPPRILPP 404
            HTYLPPPYPG+ Q Q GPFQA+   YHLYYG S+GSYQFSMV     GG+RSP R+L  
Sbjct: 304 HHTYLPPPYPGAPQNQSGPFQANPSPYHLYYGTSSGSYQFSMVAGSSSGGDRSPTRMLAS 363

Query: 405 CTNASTGSA---LLNPSLPNQSDVVEAEGSHSNSPTNMAPSARLEEAVWRPY 453
           CT+++   A   L+NPSL  QSD VEA+GSHSNSPT ++   R++EAVWRPY
Sbjct: 364 CTSSAASVAAGNLMNPSLGGQSDGVEADGSHSNSPTALSTPGRMDEAVWRPY 415


>gi|72534652 runt-related transcription factor 3 isoform 1 [Homo
           sapiens]
          Length = 429

 Score =  476 bits (1226), Expect = e-134
 Identities = 270/467 (57%), Positives = 316/467 (67%), Gaps = 76/467 (16%)

Query: 6   DASTSRRFTPPSTAL----SPGKMSEALPLGAPDAGAALAGKLRSGDRSMVEVLADHPGE 61
           D STSRRFTPPS A       GKM E     +  A     G+ R   RSMV+VLADH GE
Sbjct: 20  DPSTSRRFTPPSPAFPCGGGGGKMGENSGALSAQAAVGPGGRARPEVRSMVDVLADHAGE 79

Query: 62  LVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALGDVPDGTLVTVMAGNDENYSAELRNAT 121
           LVRTDSPNFLCSVLP+HWRCNKTLP+AFKVVALGDVPDGT+VTVMAGNDENYSAELRNA+
Sbjct: 80  LVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGDVPDGTVVTVMAGNDENYSAELRNAS 139

Query: 122 AAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKITVDGPREPRRHRQ 181
           A MKNQVARFNDLRFVGRSGRGKSFTLTITVFTNP QVATYHRAIK+TVDGPREPRRHRQ
Sbjct: 140 AVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPTQVATYHRAIKVTVDGPREPRRHRQ 199

Query: 182 KLDDQTKPGSLSFSERLSELEQLRRTAMRVSPHHPAPTPNPRASLNHSTAFNPQPQSQMQ 241
           KL+DQTKP    F +R  +LE+LR   MRV+P     TP+PR SL+ ++ F+ QPQ+ +Q
Sbjct: 200 KLEDQTKP----FPDRFGDLERLR---MRVTP----STPSPRGSLSTTSHFSSQPQTPIQ 248

Query: 242 DTRQIQP-SPPWSYDQSYQYLGSIASPSVHPATPISPGRASGMTTLSAELSSRLSTAPDL 300
            T ++ P S P  +D+S+                                     T P L
Sbjct: 249 GTSELNPFSDPRQFDRSF------------------------------------PTLPTL 272

Query: 301 TAFSDPRQFPALPSISDPRMHYPG----AFTYSPTPV-TSGIGIGMSAMGSATRY-HTYL 354
           T      +FP      DPRMHYPG    AF YS TP  TS   + ++ M + +R+ HTYL
Sbjct: 273 T----ESRFP------DPRMHYPGAMSAAFPYSATPSGTSISSLSVAGMPATSRFHHTYL 322

Query: 355 PPPYPGSSQAQGGPFQASSPSYHLYYGASAGSYQFSMV-----GGERSPPRILPPCTNAS 409
           PPPYPG+ Q Q GPFQA+   YHLYYG S+GSYQFSMV     GG+RSP R+L  CT+++
Sbjct: 323 PPPYPGAPQNQSGPFQANPSPYHLYYGTSSGSYQFSMVAGSSSGGDRSPTRMLASCTSSA 382

Query: 410 TGSA---LLNPSLPNQSDVVEAEGSHSNSPTNMAPSARLEEAVWRPY 453
              A   L+NPSL  QSD VEA+GSHSNSPT ++   R++EAVWRPY
Sbjct: 383 ASVAAGNLMNPSLGGQSDGVEADGSHSNSPTALSTPGRMDEAVWRPY 429


>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
          Length = 2285

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 64/227 (28%), Positives = 93/227 (40%), Gaps = 37/227 (16%)

Query: 213 PHHPAPTPNPRASLNHSTAFNPQPQSQM-QDTRQIQPSPPWSYDQSYQYLGSIASPSVHP 271
           P  PAP+     +L+   A+ PQPQSQ  Q T   Q   P   + S    GS AS     
Sbjct: 565 PQQPAPS-----TLSQQAAY-PQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQAS----- 613

Query: 272 ATPISPGRASGMTTLSAELSSRLSTAPDLTAFSDPRQFPALPSISDPRMHYPGAFTYSPT 331
           + P       G   ++  L SR S+ PDL+            SI D  M   GA   SP 
Sbjct: 614 SAPSMTSSKGGQEDMNLSLQSRPSSLPDLSG-----------SIDDLPMGTEGAL--SPG 660

Query: 332 PVTSGIGI--GMSAMGSATRYHTYLPPPYPGSSQAQGGPFQASSPSYHLYYGASAGSYQF 389
             TSGI    G  +  + + +  +  P  PG      GP  +   S      + +G    
Sbjct: 661 VSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIR----GPSPSPVGSPASVAQSRSGPLSP 716

Query: 390 SMVGGERSPPRILPPCTNASTGSALLNPSLPNQSDVVEAEGSHSNSP 436
           + V G + PPR  PP   +    ++++PS+ NQS + +  G    +P
Sbjct: 717 AAVPGNQMPPR--PP---SGQSDSIMHPSM-NQSSIAQDRGYMQRNP 757



 Score = 30.4 bits (67), Expect = 3.4
 Identities = 48/202 (23%), Positives = 70/202 (34%), Gaps = 20/202 (9%)

Query: 232 FNPQPQSQMQDTRQIQPSPPWSYDQSYQYLGSIASPSVHPATPISPGRASGMTTLSAELS 291
           F+P     +   R   PSP  S     Q      SP+  P   + P   SG +      S
Sbjct: 681 FSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPS 740

Query: 292 SRLSTAPDLTAFSDPRQFPALPSISDPRMHYPGAFTYSPTPVTSGIGIGMSAMGSATRYH 351
              S+      +   ++ P +P  S P+   PG+      P    I  G   MGS  +  
Sbjct: 741 MNQSSIAQDRGYM--QRNPQMPQYSSPQ---PGSALSPRQPSGGQIHTG---MGSYQQNS 792

Query: 352 TYLPPPYPGSSQAQGG----PFQASSPSYHLYYGASAGSYQFSMVGGER------SPPRI 401
                P  G    QGG    P   + P+ +      AG       GG+        P   
Sbjct: 793 MGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGT 852

Query: 402 LPP--CTNASTGSALLNPSLPN 421
           LPP   ++AS G+    P++ N
Sbjct: 853 LPPGRMSHASMGNRPYGPNMAN 874


>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
          Length = 2068

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 64/227 (28%), Positives = 93/227 (40%), Gaps = 37/227 (16%)

Query: 213 PHHPAPTPNPRASLNHSTAFNPQPQSQM-QDTRQIQPSPPWSYDQSYQYLGSIASPSVHP 271
           P  PAP+     +L+   A+ PQPQSQ  Q T   Q   P   + S    GS AS     
Sbjct: 565 PQQPAPS-----TLSQQAAY-PQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQAS----- 613

Query: 272 ATPISPGRASGMTTLSAELSSRLSTAPDLTAFSDPRQFPALPSISDPRMHYPGAFTYSPT 331
           + P       G   ++  L SR S+ PDL+            SI D  M   GA   SP 
Sbjct: 614 SAPSMTSSKGGQEDMNLSLQSRPSSLPDLSG-----------SIDDLPMGTEGAL--SPG 660

Query: 332 PVTSGIGI--GMSAMGSATRYHTYLPPPYPGSSQAQGGPFQASSPSYHLYYGASAGSYQF 389
             TSGI    G  +  + + +  +  P  PG      GP  +   S      + +G    
Sbjct: 661 VSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIR----GPSPSPVGSPASVAQSRSGPLSP 716

Query: 390 SMVGGERSPPRILPPCTNASTGSALLNPSLPNQSDVVEAEGSHSNSP 436
           + V G + PPR  PP   +    ++++PS+ NQS + +  G    +P
Sbjct: 717 AAVPGNQMPPR--PP---SGQSDSIMHPSM-NQSSIAQDRGYMQRNP 757



 Score = 30.4 bits (67), Expect = 3.4
 Identities = 48/202 (23%), Positives = 70/202 (34%), Gaps = 20/202 (9%)

Query: 232 FNPQPQSQMQDTRQIQPSPPWSYDQSYQYLGSIASPSVHPATPISPGRASGMTTLSAELS 291
           F+P     +   R   PSP  S     Q      SP+  P   + P   SG +      S
Sbjct: 681 FSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPS 740

Query: 292 SRLSTAPDLTAFSDPRQFPALPSISDPRMHYPGAFTYSPTPVTSGIGIGMSAMGSATRYH 351
              S+      +   ++ P +P  S P+   PG+      P    I  G   MGS  +  
Sbjct: 741 MNQSSIAQDRGYM--QRNPQMPQYSSPQ---PGSALSPRQPSGGQIHTG---MGSYQQNS 792

Query: 352 TYLPPPYPGSSQAQGG----PFQASSPSYHLYYGASAGSYQFSMVGGER------SPPRI 401
                P  G    QGG    P   + P+ +      AG       GG+        P   
Sbjct: 793 MGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQPGIPPYGT 852

Query: 402 LPP--CTNASTGSALLNPSLPN 421
           LPP   ++AS G+    P++ N
Sbjct: 853 LPPGRMSHASMGNRPYGPNMAN 874


>gi|28558973 mediator complex subunit 14 [Homo sapiens]
          Length = 1454

 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 57/236 (24%), Positives = 84/236 (35%), Gaps = 24/236 (10%)

Query: 218  PTPNPRASLNHSTAFNPQPQSQMQDTRQIQPSPPWSYDQSYQYLGSIASPSVHPATPISP 277
            P P  +  LN     N   + +  +     PSP    D     +  +  P      P  P
Sbjct: 955  PAPGLKTFLNMFVDSNQDARRRSVNEDDNPPSPIGG-DMMDSLISQLQPPPQQQPFPKQP 1013

Query: 278  GRASG--MTTLSAELSSRLSTAPDLTAFSDPRQFPALPSISDP-RMHYPGAFTYSPTPVT 334
            G +    +T+      S ++ +P +     P    A  S S   R   P +F  +P P +
Sbjct: 1014 GTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPSPASFVPTPPPSS 1073

Query: 335  SGIGIGMSAMGSATRYHTYLPPPYPGSSQAQGGPFQASSPSYHLYYGASAGSYQFSMVGG 394
             GI IG  A  S    H  L P           P+   SPS        AG++  S    
Sbjct: 1074 HGISIGPGA--SFASPHGTLDP---------SSPYTMVSPS------GRAGNWPGSPQVS 1116

Query: 395  ERSPPRILPPCTNASTGSALLNPSLPNQSDVVEAEGSHSNSPTNMAPSARLEEAVW 450
              SP   +P  + A+     L+  +P+ S    A  S    PTNM P  +L +  W
Sbjct: 1117 GPSPAARMPGMSPANPS---LHSPVPDASHSPRAGTSSQTMPTNMPPPRKLPQRSW 1169


>gi|21536357 TBP-associated factor 6 isoform delta [Homo sapiens]
          Length = 667

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 54/203 (26%), Positives = 78/203 (38%), Gaps = 30/203 (14%)

Query: 200 ELEQLRRTAMRVSPHHP------APTPNPRA----SLNHSTAFNPQPQSQMQDTRQIQPS 249
           + +Q+ RT + ++   P      AP P PR      +  S A   Q     +     QPS
Sbjct: 463 QAQQVNRTTLTITQPRPTLTLSQAPQPGPRTPGLLKVPGSIALPVQTLVSARAAAPPQPS 522

Query: 250 PPWSYDQSYQYLGSIASPSVHPATPISPGR-ASGMTTLS------------AELSSRLST 296
           PP +  +      S ++PS      +S     SG TT S             +L S  +T
Sbjct: 523 PPPT--KFIVMSSSSSAPSTQQVLSLSTSAPGSGSTTTSPVTTTVPSVQPIVKLVSTATT 580

Query: 297 APDLTAFSDPRQFPALPSIS-DPRMHYPGAFTYSPTPV----TSGIGIGMSAMGSATRYH 351
           AP  TA S P        +S  P     G  T  P+PV    +S   +  SA+    +  
Sbjct: 581 APPSTAPSGPGSVQKYIVVSLPPTGEGKGGPTSHPSPVPPPASSPSPLSGSALCGGKQEA 640

Query: 352 TYLPPPYPGSSQAQGGPFQASSP 374
              PPP PG+ +A G    + SP
Sbjct: 641 GDSPPPAPGTPKANGSQPNSGSP 663


>gi|5032147 TBP-associated factor 6 isoform alpha [Homo sapiens]
          Length = 677

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 54/203 (26%), Positives = 78/203 (38%), Gaps = 30/203 (14%)

Query: 200 ELEQLRRTAMRVSPHHP------APTPNPRA----SLNHSTAFNPQPQSQMQDTRQIQPS 249
           + +Q+ RT + ++   P      AP P PR      +  S A   Q     +     QPS
Sbjct: 473 QAQQVNRTTLTITQPRPTLTLSQAPQPGPRTPGLLKVPGSIALPVQTLVSARAAAPPQPS 532

Query: 250 PPWSYDQSYQYLGSIASPSVHPATPISPGR-ASGMTTLS------------AELSSRLST 296
           PP +  +      S ++PS      +S     SG TT S             +L S  +T
Sbjct: 533 PPPT--KFIVMSSSSSAPSTQQVLSLSTSAPGSGSTTTSPVTTTVPSVQPIVKLVSTATT 590

Query: 297 APDLTAFSDPRQFPALPSIS-DPRMHYPGAFTYSPTPV----TSGIGIGMSAMGSATRYH 351
           AP  TA S P        +S  P     G  T  P+PV    +S   +  SA+    +  
Sbjct: 591 APPSTAPSGPGSVQKYIVVSLPPTGEGKGGPTSHPSPVPPPASSPSPLSGSALCGGKQEA 650

Query: 352 TYLPPPYPGSSQAQGGPFQASSP 374
              PPP PG+ +A G    + SP
Sbjct: 651 GDSPPPAPGTPKANGSQPNSGSP 673


>gi|21536359 TBP-associated factor 6 isoform alpha [Homo sapiens]
          Length = 677

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 54/203 (26%), Positives = 78/203 (38%), Gaps = 30/203 (14%)

Query: 200 ELEQLRRTAMRVSPHHP------APTPNPRA----SLNHSTAFNPQPQSQMQDTRQIQPS 249
           + +Q+ RT + ++   P      AP P PR      +  S A   Q     +     QPS
Sbjct: 473 QAQQVNRTTLTITQPRPTLTLSQAPQPGPRTPGLLKVPGSIALPVQTLVSARAAAPPQPS 532

Query: 250 PPWSYDQSYQYLGSIASPSVHPATPISPGR-ASGMTTLS------------AELSSRLST 296
           PP +  +      S ++PS      +S     SG TT S             +L S  +T
Sbjct: 533 PPPT--KFIVMSSSSSAPSTQQVLSLSTSAPGSGSTTTSPVTTTVPSVQPIVKLVSTATT 590

Query: 297 APDLTAFSDPRQFPALPSIS-DPRMHYPGAFTYSPTPV----TSGIGIGMSAMGSATRYH 351
           AP  TA S P        +S  P     G  T  P+PV    +S   +  SA+    +  
Sbjct: 591 APPSTAPSGPGSVQKYIVVSLPPTGEGKGGPTSHPSPVPPPASSPSPLSGSALCGGKQEA 650

Query: 352 TYLPPPYPGSSQAQGGPFQASSP 374
              PPP PG+ +A G    + SP
Sbjct: 651 GDSPPPAPGTPKANGSQPNSGSP 673


>gi|56549666 tyrosine kinase, non-receptor, 2 isoform 1 [Homo
           sapiens]
          Length = 1038

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 35/137 (25%), Positives = 60/137 (43%), Gaps = 7/137 (5%)

Query: 189 PGSLSFSERLSELEQLRRTAMRVSPHHPAPTPNPRASLNHSTAFN-PQPQSQMQDTRQIQ 247
           P S   +E    L+Q     ++     PAP+P+P            P P    +   Q+ 
Sbjct: 698 PSSAQTAEIFQALQQECMRQLQAPAGSPAPSPSPGGDDKPQVPPRVPIPPRPTRPHVQLS 757

Query: 248 PSPPWSYDQSYQYLGSIASPSVHPATPISPGRASGMTTL----SAELSSRLSTAPDLTAF 303
           P+PP   +++ Q+ G  + P V P  P+SP  +   + L    S+ L  RLS++P  T  
Sbjct: 758 PAPP-GEEETSQWPGPASPPRVPPREPLSPQGSRTPSPLVPPGSSPLPPRLSSSPGKT-M 815

Query: 304 SDPRQFPALPSISDPRM 320
              + F + P  + P++
Sbjct: 816 PTTQSFASDPKYATPQV 832


>gi|58331191 tyrosine kinase, non-receptor, 2 isoform 2 [Homo
           sapiens]
          Length = 1086

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 35/137 (25%), Positives = 60/137 (43%), Gaps = 7/137 (5%)

Query: 189 PGSLSFSERLSELEQLRRTAMRVSPHHPAPTPNPRASLNHSTAFN-PQPQSQMQDTRQIQ 247
           P S   +E    L+Q     ++     PAP+P+P            P P    +   Q+ 
Sbjct: 776 PSSAQTAEIFQALQQECMRQLQAPAGSPAPSPSPGGDDKPQVPPRVPIPPRPTRPHVQLS 835

Query: 248 PSPPWSYDQSYQYLGSIASPSVHPATPISPGRASGMTTL----SAELSSRLSTAPDLTAF 303
           P+PP   +++ Q+ G  + P V P  P+SP  +   + L    S+ L  RLS++P  T  
Sbjct: 836 PAPP-GEEETSQWPGPASPPRVPPREPLSPQGSRTPSPLVPPGSSPLPPRLSSSPGKT-M 893

Query: 304 SDPRQFPALPSISDPRM 320
              + F + P  + P++
Sbjct: 894 PTTQSFASDPKYATPQV 910


>gi|55750053 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 62/239 (25%), Positives = 84/239 (35%), Gaps = 32/239 (13%)

Query: 208 AMRVSPHHPAPTPNPRASLNHSTAFN---PQPQSQMQDTRQIQPSPPWSYDQSYQYLGSI 264
           ++R  P  PA  P P + +++S A     P   S    +   Q S P S+    Q  G  
Sbjct: 538 SLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQ--GPQ 595

Query: 265 ASPSVHPATPISPGRASGMTTLSAELSSRLSTAPDLTAFSDPRQFPALPSISDPRMHYPG 324
            +P   P  P        +TT SA LS+ ++T     A       P  P     R   PG
Sbjct: 596 GAPYPFPPVPT-------VTTSSATLSTVIATVASSPAGYKTASPPGPPPYGK-RAPSPG 647

Query: 325 AFTYSPTPVTSGIGIGMSAMGSATRYHTYLPPPYPGSSQAQG-GPFQASSPSYHLYYGAS 383
           A+  +  P            GS   + T  PP Y G+S   G G F+  SP        +
Sbjct: 648 AYKTATPPGYKP--------GSPPSFRTGTPPGYRGTSPPAGPGTFKPGSP--------T 691

Query: 384 AGSYQFSMVGGERSPPRILPPCTNASTGSALLNPSLPNQSDVVEAEGSHSNSPTNMAPS 442
            G       G    P   LPP   A      L+ +   Q    E E   S  P   +PS
Sbjct: 692 VGPGPLPPAGPSGLPS--LPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPS 748



 Score = 34.3 bits (77), Expect = 0.24
 Identities = 58/230 (25%), Positives = 83/230 (36%), Gaps = 36/230 (15%)

Query: 208 AMRVSPHHPAPTPNPRA-SLNHSTAFNPQPQSQMQDTRQIQPSPPWSYDQSYQYLGSIAS 266
           A +  P +P   P P + S+++      QP    Q      P PP  Y +       +A+
Sbjct: 401 ASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRL------LAN 454

Query: 267 PSVHPATPISPGRASGMTTLSAELSSRLSTAPDLTAFSDPRQFPALPSISDPRMHY---- 322
            + HP  P  P   +  T         +ST          +Q          + H+    
Sbjct: 455 SNAHPG-PFPPSTGAQSTA-----HPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSG 508

Query: 323 ---PGAFTYSPTPVTSGIG-----IGMS-AMGSATRYH---TYLPPPYPGSSQAQGGP-F 369
              PGAF   P P+  G         MS ++GS   Y     +LPPP+   S +Q GP  
Sbjct: 509 PPPPGAF---PHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNG 565

Query: 370 QASSPSYHLYYGASAGSYQFSMVGGERSP---PRILPPCTNASTGSALLN 416
              S S +     S GSY  S     + P   P   PP    +T SA L+
Sbjct: 566 PPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLS 615


>gi|55750041 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 62/239 (25%), Positives = 84/239 (35%), Gaps = 32/239 (13%)

Query: 208 AMRVSPHHPAPTPNPRASLNHSTAFN---PQPQSQMQDTRQIQPSPPWSYDQSYQYLGSI 264
           ++R  P  PA  P P + +++S A     P   S    +   Q S P S+    Q  G  
Sbjct: 538 SLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQ--GPQ 595

Query: 265 ASPSVHPATPISPGRASGMTTLSAELSSRLSTAPDLTAFSDPRQFPALPSISDPRMHYPG 324
            +P   P  P        +TT SA LS+ ++T     A       P  P     R   PG
Sbjct: 596 GAPYPFPPVPT-------VTTSSATLSTVIATVASSPAGYKTASPPGPPPYGK-RAPSPG 647

Query: 325 AFTYSPTPVTSGIGIGMSAMGSATRYHTYLPPPYPGSSQAQG-GPFQASSPSYHLYYGAS 383
           A+  +  P            GS   + T  PP Y G+S   G G F+  SP        +
Sbjct: 648 AYKTATPPGYKP--------GSPPSFRTGTPPGYRGTSPPAGPGTFKPGSP--------T 691

Query: 384 AGSYQFSMVGGERSPPRILPPCTNASTGSALLNPSLPNQSDVVEAEGSHSNSPTNMAPS 442
            G       G    P   LPP   A      L+ +   Q    E E   S  P   +PS
Sbjct: 692 VGPGPLPPAGPSGLPS--LPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPS 748



 Score = 34.3 bits (77), Expect = 0.24
 Identities = 58/230 (25%), Positives = 83/230 (36%), Gaps = 36/230 (15%)

Query: 208 AMRVSPHHPAPTPNPRA-SLNHSTAFNPQPQSQMQDTRQIQPSPPWSYDQSYQYLGSIAS 266
           A +  P +P   P P + S+++      QP    Q      P PP  Y +       +A+
Sbjct: 401 ASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRL------LAN 454

Query: 267 PSVHPATPISPGRASGMTTLSAELSSRLSTAPDLTAFSDPRQFPALPSISDPRMHY---- 322
            + HP  P  P   +  T         +ST          +Q          + H+    
Sbjct: 455 SNAHPG-PFPPSTGAQSTA-----HPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSG 508

Query: 323 ---PGAFTYSPTPVTSGIG-----IGMS-AMGSATRYH---TYLPPPYPGSSQAQGGP-F 369
              PGAF   P P+  G         MS ++GS   Y     +LPPP+   S +Q GP  
Sbjct: 509 PPPPGAF---PHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNG 565

Query: 370 QASSPSYHLYYGASAGSYQFSMVGGERSP---PRILPPCTNASTGSALLN 416
              S S +     S GSY  S     + P   P   PP    +T SA L+
Sbjct: 566 PPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLS 615


>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
          Length = 1970

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 55/222 (24%), Positives = 82/222 (36%), Gaps = 25/222 (11%)

Query: 207  TAMRVSPHHPAPTPNPRASLNHSTAFNPQPQSQMQDTRQIQPSPPWSYDQSYQYLGSIAS 266
            T+   SP  P+ +P   +    S +++P   S    +    P+ P     S  Y  S  S
Sbjct: 1632 TSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSY--SPTS 1689

Query: 267  PSVHPATP----ISPGRASGMTTLSAELSSRLSTAPDLTAFSDPRQFPALPSISDPRMHY 322
            PS  P +P     SP  +    + S    S   T+P  +  S P   P  PS S    +Y
Sbjct: 1690 PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTS-PSYSPTSPSYSPTSPNY 1748

Query: 323  -PGAFTYSPTPVTSGIGIGMSAMGSATRYHTYLPPPYPGSSQAQGGPFQASSPSYHLYYG 381
             P +  Y+PT          S   ++  Y    P   P S       +  +SPSY     
Sbjct: 1749 SPTSPNYTPT--------SPSYSPTSPSYSPTSPNYTPTSPN-----YSPTSPSY----S 1791

Query: 382  ASAGSYQFSMVGGERSPPRILPPCTNASTGSALLNPSLPNQS 423
             ++ SY  +      S PR  P     +  S   +PS P+ S
Sbjct: 1792 PTSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYS 1833



 Score = 38.5 bits (88), Expect = 0.013
 Identities = 52/193 (26%), Positives = 74/193 (38%), Gaps = 22/193 (11%)

Query: 207  TAMRVSPHHPAPTPNPRASLNHSTAFNPQPQSQMQDTRQIQPSPPWSYDQSYQYLGSI-- 264
            T+   SP  P  TP        S +++P   S    +    PS P    QS  Y  S   
Sbjct: 1765 TSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPS 1824

Query: 265  ---ASPSVHPA----TPISPGRASGMTTLSAELSSRLSTAPDLTAFSDPRQFPALPSISD 317
               +SPS  P     TP SP  +      +        T+P  +  S P+  P  P+ S 
Sbjct: 1825 YSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTS-PKYSPTSPTYSP 1883

Query: 318  PRMHY-PGAFTYSPT-PVTSGIGIGMSAMG-----SATRYH----TYLPPPYPGSSQAQG 366
                Y P + TYSPT PV +      S        ++ +Y     TY P    GS+ +  
Sbjct: 1884 TTPKYSPTSPTYSPTSPVYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPT 1943

Query: 367  GP-FQASSPSYHL 378
             P +  +SP+Y L
Sbjct: 1944 SPGYSPTSPTYSL 1956



 Score = 31.2 bits (69), Expect = 2.0
 Identities = 49/185 (26%), Positives = 66/185 (35%), Gaps = 36/185 (19%)

Query: 266  SPSVHP----ATPI----SPGRASGMTTLSAELSSRLSTAPDLTAFSDPRQFPALPSISD 317
            SP++ P    ATP     SP   SGMT  +A  S   S A D + FS P   PA      
Sbjct: 1514 SPAMTPWNQGATPAYGAWSPSVGSGMTPGAAGFSP--SAASDASGFS-PGYSPA------ 1564

Query: 318  PRMHYPGAFTYSPTPVTSGIGIGMSAMGSATRYHTYLPPPYPGSSQAQGGPFQASSPSYH 377
                      +SPTP          + GS      Y+P P    S +      A  P   
Sbjct: 1565 ----------WSPTP---------GSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSP 1605

Query: 378  LYYGASAGSYQFSMVGGERSPPRILPPCTNASTGSALLNPSLPNQSDVVEAEGSHSNSPT 437
              Y   + SY  +      + P   P   N S  S   +P+ P+ S    +    S S +
Sbjct: 1606 GGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS 1665

Query: 438  NMAPS 442
              +PS
Sbjct: 1666 PTSPS 1670


>gi|56549668 AT rich interactive domain 2 (ARID, RFX-like) [Homo
            sapiens]
          Length = 1835

 Score = 38.9 bits (89), Expect = 0.010
 Identities = 45/164 (27%), Positives = 66/164 (40%), Gaps = 26/164 (15%)

Query: 208  AMRVSPHHPAPTPNPRASLNHSTAFNPQPQSQMQDTRQ--IQPSPPWSYDQSYQYLGSIA 265
            A RV   + AP P P   ++ +    P  Q Q Q T+Q  +  S P    Q+Y       
Sbjct: 888  ASRVGFQNIAPKPLPSQQVSSTVVQQPIQQPQ-QPTQQSVVIVSQPAQQGQTY------- 939

Query: 266  SPSVHPATPISPGRASGMTTLSAELSSRLSTAPDLTAFSDPRQFPALPSISDPRMHYPGA 325
            +P++H     +P        L A  + +L+  P++T  S P   PA  +        P A
Sbjct: 940  APAIHQIVLANPA------ALPAGQTVQLTGQPNITPSSSPSPVPATNN------QVPTA 987

Query: 326  FTYSPTPVTSGIGIGMSAMGSATR----YHTYLPPPYPGSSQAQ 365
             + S TP + G    +S M S  R     H+  PPP     Q Q
Sbjct: 988  MSSSSTPQSQGPPPTVSQMLSVKRQQQQQHSPAPPPQQVQVQVQ 1031


>gi|22027471 neuronal PAS domain protein 2 [Homo sapiens]
          Length = 824

 Score = 38.5 bits (88), Expect = 0.013
 Identities = 38/118 (32%), Positives = 49/118 (41%), Gaps = 15/118 (12%)

Query: 197 RLSELEQL--RRTAMRVSPHHPAPTPNPRASLNHSTAFNPQPQSQMQDTRQIQPSPPWSY 254
           R S+L Q   R  +  VSP   A    P  SLN +T     P S  QD  Q QPSP +S+
Sbjct: 615 RSSQLMQSSGRSGSSLVSPFSSATAALP-PSLNLTT-----PASTSQDASQCQPSPDFSH 668

Query: 255 DQSYQYLGSIASPSVHPATPISPGRASGMTTLSAELSSR-LSTAPDLTAFSDPRQFPA 311
           D+  + L S       P  P+ PG            + R +  A   T F +P   PA
Sbjct: 669 DRQLRLLLS------QPIQPMMPGSCDARQPSEVSRTGRQVKYAQSQTVFQNPDAHPA 720


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 38.5 bits (88), Expect = 0.013
 Identities = 48/191 (25%), Positives = 59/191 (30%), Gaps = 16/191 (8%)

Query: 213 PHHPAPTPNPRASLNHSTAFNPQPQSQMQDTRQIQPSPPWSYDQSYQYLGSIASP--SVH 270
           P  P P P P            QP  Q    +Q  P  P  + Q +Q       P  S  
Sbjct: 56  PKPPIPPPPPHQQ-------QQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSK 108

Query: 271 PATPISPGRASGMTTLSAELSSRLSTAPDLTAFSDPRQFPALPSISDPRMHYPGAFTYSP 330
           P     PG A G+ +     SS     P  T+ + P   P       P +         P
Sbjct: 109 PVVAQGPGPAPGVGSAPPASSSAPPATPP-TSGAPPGSGPGPTPTPPPAVTSAPPGAPPP 167

Query: 331 TPVTSGIGIGMSAMGSATRYHTYLPPPYPGSSQ--AQGGPFQASSPSYHLYYGASAGSYQ 388
           TP +SG+       G        +P P PG  Q    GGP     P          G   
Sbjct: 168 TPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPG----GPKPGGGPG 223

Query: 389 FSMVGGERSPP 399
            S  GG   PP
Sbjct: 224 LSTPGGHPKPP 234


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 38.1 bits (87), Expect = 0.017
 Identities = 31/124 (25%), Positives = 47/124 (37%), Gaps = 6/124 (4%)

Query: 216  PAPTPNPRASLNHSTA----FNPQPQSQMQDTRQIQPSPPWSYDQSYQYLGSIASPSVHP 271
            P PT  P   ++ +T       P P +         PSPP +   +     + + P+  P
Sbjct: 1448 PPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTP 1507

Query: 272  ATPISPGRASGMTTLSAELSSRLSTAPDLTAFSDPRQFPALPSISDPRMHYPGAFTYSPT 331
             TP +       TT  +  ++  +T P  T  S P   P  P  S   +  P   T SP 
Sbjct: 1508 ITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTL--PPTTTPSPP 1565

Query: 332  PVTS 335
            P T+
Sbjct: 1566 PTTT 1569



 Score = 34.3 bits (77), Expect = 0.24
 Identities = 32/123 (26%), Positives = 51/123 (41%), Gaps = 9/123 (7%)

Query: 218  PTPNPRASLNHSTAFNPQPQSQMQDTRQIQPSPPWSYDQSYQYLGSI-----ASPSVHPA 272
            PT    A +   T  NP P+S    T +   SP     +S   L ++      + +  P+
Sbjct: 4198 PTHTSTAPIAELTTSNPPPESSTPQTSRSTSSP---LTESTTLLSTLPPAIEMTSTAPPS 4254

Query: 273  TPISPGRASGMTTLSAELSSRLSTAPDLTAFSDPRQFPALPSISDPRMHYPGAFTYSPTP 332
            TP +P   SG  TLS   S+  S  P            + P+ S  +     A+T +PTP
Sbjct: 4255 TPTAPTTTSGGHTLSPPPSTTTS-PPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTP 4313

Query: 333  VTS 335
            +++
Sbjct: 4314 LST 4316



 Score = 31.2 bits (69), Expect = 2.0
 Identities = 51/229 (22%), Positives = 75/229 (32%), Gaps = 17/229 (7%)

Query: 216  PAPTPNPRASLNHSTAFNPQPQSQMQDTRQIQPSPPWSYDQSYQYLGSIASPSVHPATPI 275
            P   P    +L  +T  +P P +         PSPP +   S   + +   P   P T  
Sbjct: 1546 PITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPP---PTTTP 1602

Query: 276  SPGRASGMTTLSAELSSRLSTAPDLTAFSDPRQFPALPSISDPRMHYPGAFTYSPTPVTS 335
            SP      TT +    +   + P  T  + P     LP  + P    P   T +P P T+
Sbjct: 1603 SP----PTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSP--PPTTTTTPPPTTT 1656

Query: 336  GIGIGMSAMGSATRYHTYLPPPYPGSSQAQGGPFQASSPSYHLYYGASAGSYQFSMVGGE 395
                  +         T  PP    SS     P    SP        S  +   S +   
Sbjct: 1657 PSPPTTTTPSPPITTTTTPPPTTTPSSPITTTP----SPPTTTMTTPSPTTTPSSPITTT 1712

Query: 396  RSPPRIL---PPCTNASTGSALLNPSLPNQSDVVEAEGSHSNSPTNMAP 441
             +P       PP T  +T S    PS P  + +     + ++SP    P
Sbjct: 1713 TTPSSTTTPSPPPTTMTTPSPTTTPS-PPTTTMTTLPPTTTSSPLTTTP 1760



 Score = 30.8 bits (68), Expect = 2.6
 Identities = 30/117 (25%), Positives = 45/117 (38%), Gaps = 15/117 (12%)

Query: 219  TPNPRASLNHSTAFNPQPQSQMQDTRQIQPSPPWSYDQSYQYLGSIASPSVHPATPISPG 278
            TP+P      +T  +P P S         PSPP +   +         P+  P+ PI+  
Sbjct: 1398 TPSPP-----TTTPSPPPTSTTTLPPTTTPSPPTTTTTT-------PPPTTTPSPPITTT 1445

Query: 279  RASGMTTLSAELSSRLSTAPDLTAFSDPRQFPALPSISDPRMHYPGAFTYSPTPVTS 335
                 TT  +   S  +T P  T  S P   P+ P+ +      P   T +P P T+
Sbjct: 1446 TTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSP---PTTTTTTPPPTTT 1499



 Score = 30.8 bits (68), Expect = 2.6
 Identities = 33/133 (24%), Positives = 48/133 (36%), Gaps = 21/133 (15%)

Query: 216  PAPTPNPRASLNHS----TAFNPQPQSQMQDTRQIQPSPPWSYDQSYQYLGSIASPSVHP 271
            P  TP+P  +   S    T   P P +         PSPP +   +     + +SP    
Sbjct: 1653 PTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTT 1712

Query: 272  ATPISPGRAS---------GMTTLSAELSSRLSTAPDLTAFSDPRQFPALPSISDPRMHY 322
             TP S    S           TT  +  ++ ++T P  T  S     P  PSI+ P    
Sbjct: 1713 TTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPP---- 1768

Query: 323  PGAFTYSPTPVTS 335
                T+SP   T+
Sbjct: 1769 ----TFSPFSTTT 1777



 Score = 29.3 bits (64), Expect = 7.7
 Identities = 35/146 (23%), Positives = 52/146 (35%), Gaps = 20/146 (13%)

Query: 216  PAPTPNPRASLNHSTAFNPQPQSQMQDTRQIQPSPPWSYDQSYQYLGSIASPSVHPATPI 275
            P+P P    +L  +T  +P   +         PSPP +         +   P+  P+ PI
Sbjct: 1406 PSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPIT-------TTTTPPPTTTPSPPI 1458

Query: 276  SPGRASGMTTLSAELSSRLSTAPDLTAFSDPRQFPALP---SISDPRMHYPGAFTYSP-T 331
            S       TT         + +P  T  S P   P+ P   + + P    P   T +P T
Sbjct: 1459 STTTTPPPTT---------TPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPIT 1509

Query: 332  PVTSGIGIGMSAMGSATRYHTYLPPP 357
            P  S   +  +   S     T  PPP
Sbjct: 1510 PPASTTTLPPTTTPSPPTTTTTTPPP 1535



 Score = 29.3 bits (64), Expect = 7.7
 Identities = 29/124 (23%), Positives = 42/124 (33%), Gaps = 2/124 (1%)

Query: 213  PHHPAPTPNPRASLNHSTAFNPQPQSQMQDTRQ--IQPSPPWSYDQSYQYLGSIASPSVH 270
            P     TP P  + +  T   P P +    T      PSPP +   +     + + P+  
Sbjct: 1565 PPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTT 1624

Query: 271  PATPISPGRASGMTTLSAELSSRLSTAPDLTAFSDPRQFPALPSISDPRMHYPGAFTYSP 330
            P TP +       TT  +   +  +T P  T  S P      P I+      P     SP
Sbjct: 1625 PITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSP 1684

Query: 331  TPVT 334
               T
Sbjct: 1685 ITTT 1688


>gi|5454064 RNA binding motif protein 14 [Homo sapiens]
          Length = 669

 Score = 38.1 bits (87), Expect = 0.017
 Identities = 48/169 (28%), Positives = 67/169 (39%), Gaps = 22/169 (13%)

Query: 222 PRASLNHSTAFNPQPQSQMQDTRQIQPSPPWSYDQSYQYLGSIASPSVHPATPISPGRAS 281
           P ASL     +  QP +    + + QPS          Y G +ASPS   A   S G   
Sbjct: 253 PSASLG--VGYRTQPMTAQAASYRAQPS----VSLGAPYRGQLASPSSQSAAASSLGPYG 306

Query: 282 GMTTLSAELSS---RLSTAPDLTAFSDPRQFPALPSISDPRMHYPGAFTYSPTPVTSGIG 338
           G    ++ LSS   + + A  L ++    Q  +L S  +    Y GA         S  G
Sbjct: 307 GAQPSASALSSYGGQAAAASSLNSYG--AQGSSLASYGNQPSSY-GA------QAASSYG 357

Query: 339 IGMSAMGSATRYHTYLPPPYPGSSQAQGGPFQASSPSYHLYYGASAGSY 387
           +      +A+ Y+T       GS  AQ   + A S +  L YGA A SY
Sbjct: 358 V----RAAASSYNTQGAASSLGSYGAQAASYGAQSAASSLAYGAQAASY 402


>gi|21536355 TBP-associated factor 6 isoform gamma [Homo sapiens]
          Length = 667

 Score = 37.4 bits (85), Expect = 0.028
 Identities = 50/180 (27%), Positives = 68/180 (37%), Gaps = 24/180 (13%)

Query: 217 APTPNPRA----SLNHSTAFNPQPQSQMQDTRQIQPSPPWSYDQSYQYLGSIASPSVHPA 272
           AP P PR      +  S A   Q     +     QPSPP +  +      S ++PS    
Sbjct: 486 APQPGPRTPGLLKVPGSIALPVQTLVSARAAAPPQPSPPPT--KFIVMSSSSSAPSTQQV 543

Query: 273 TPISPGR-ASGMTTLS------------AELSSRLSTAPDLTAFSDPRQFPALPSIS-DP 318
             +S     SG TT S             +L S  +TAP  TA S P        +S  P
Sbjct: 544 LSLSTSAPGSGSTTTSPVTTTVPSVQPIVKLVSTATTAPPSTAPSGPGSVQKYIVVSLPP 603

Query: 319 RMHYPGAFTYSPTPV----TSGIGIGMSAMGSATRYHTYLPPPYPGSSQAQGGPFQASSP 374
                G  T  P+PV    +S   +  SA+    +     PPP PG+ +A G    + SP
Sbjct: 604 TGEGKGGPTSHPSPVPPPASSPSPLSGSALCGGKQEAGDSPPPAPGTPKANGSQPNSGSP 663


>gi|32171215 CREB regulated transcription coactivator 2 [Homo
           sapiens]
          Length = 693

 Score = 37.4 bits (85), Expect = 0.028
 Identities = 62/260 (23%), Positives = 94/260 (36%), Gaps = 65/260 (25%)

Query: 214 HHPAPTPNPRASLNHST--AFNPQPQSQMQDTRQIQPSPPWSYDQSYQYLGSIASPSVHP 271
           H P   P+ ++SL++    A    PQ Q+Q +      P  S  +      S+  PS+  
Sbjct: 335 HSPLSHPSLQSSLSNPNLQASLSSPQPQLQGSHSHPSLPASSLARHVLPTTSLGHPSL-- 392

Query: 272 ATPISPGRASGMTTLSAELSSRLSTAPDLTAFSDPRQFPALPS--ISDP------RMHYP 323
           + P     +S  +T S  L +    A    A    R+ P  P   ++ P      +   P
Sbjct: 393 SAPALSSSSSSSSTSSPVLGAPSYPASTPGASPHHRRVPLSPLSLLAGPADARRSQQQLP 452

Query: 324 GAF--TYSPT--PVTSGIGIGMSAMGSATRYHTYLPPPYPGSSQAQGGPFQASSPSYHLY 379
             F  T SPT   +T G+ +  S + +  R      PPYP SS                 
Sbjct: 453 KQFSPTMSPTLSSITQGVPLDTSKLSTDQRL-----PPYPYSS----------------- 490

Query: 380 YGASAGSYQFSMVGGERSPPRILPPCTNASTGSALLNPSLPNQSDVVEAEG-------SH 432
                             P  +LP  T   T  +L  P LP+QS  V++ G       SH
Sbjct: 491 ------------------PSLVLP--TQPHTPKSLQQPGLPSQSCSVQSSGGQPPGRQSH 530

Query: 433 SNSPTNMAPSARLEEAVWRP 452
             +P    PS   +++  RP
Sbjct: 531 YGTPYPPGPSGHGQQSYHRP 550


>gi|45827755 transforming, acidic coiled-coil containing protein 2
           isoform b [Homo sapiens]
          Length = 1094

 Score = 37.4 bits (85), Expect = 0.028
 Identities = 44/187 (23%), Positives = 67/187 (35%), Gaps = 29/187 (15%)

Query: 219 TPNPRASLNHSTAFNPQPQSQMQDTRQIQPSPPWSYDQSYQYLGSIASPSVHPATPI--- 275
           T + + +L+  T  + QP    Q+ ++ Q   P S D        +A   + PA P    
Sbjct: 7   TSDNQRTLSAQTPRSAQPPGNSQNIKRKQQDTPGSPDHRDASSSPVADDIIQPAAPADLE 66

Query: 276 SPGRASG----------MTTLSAELSSRLSTAPDLTAFSDPRQFPALPSISDPRMHYPGA 325
           SP  A+            T L A+ SS    A +    + P + P  P    P +     
Sbjct: 67  SPTLAASSYHGDVVGQVSTDLIAQRSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPE 126

Query: 326 FTYSPTPVTSGIGIGMSAMGSATRYHTYLPPPYPGSSQAQGGPFQASSPSYHLYYG---- 381
            +  P P   G G             T   P  P S   +G PF+  S S+   +     
Sbjct: 127 VSTQPPPEEPGCG-----------SETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKP 175

Query: 382 -ASAGSY 387
            AS+G+Y
Sbjct: 176 IASSGTY 182


>gi|13376611 zinc finger protein 703 [Homo sapiens]
          Length = 590

 Score = 37.0 bits (84), Expect = 0.037
 Identities = 36/115 (31%), Positives = 44/115 (38%), Gaps = 19/115 (16%)

Query: 287 SAELSSRLSTAPDLTAFSDPRQFPALPSISDPRMHYPGAFTYSPTPVTSGIGIGMSAMGS 346
           S     R +T+ +L   S  R   ALP        YPGA         SG+G   +A  +
Sbjct: 464 SGPCDKRFATSEEL--LSHLRTHTALPGAEKLLAAYPGA---------SGLGSAAAAAAA 512

Query: 347 ATRYHTYLPPP-YPGS--SQAQGGPFQASSPSYHLYYGASAGSYQFSMVGGERSP 398
           A   H +LPPP  PGS  S +   P       YH Y     G    S  GG   P
Sbjct: 513 AASCHLHLPPPAAPGSPGSLSLRNPHTLGLSRYHPY-----GKSHLSTAGGLAVP 562


>gi|193083129 MAP/microtubule affinity-regulating kinase 3 isoform d
           [Homo sapiens]
          Length = 713

 Score = 37.0 bits (84), Expect = 0.037
 Identities = 30/91 (32%), Positives = 48/91 (52%), Gaps = 22/91 (24%)

Query: 217 APTPN----PRASLNHSTAFNPQPQSQMQDTRQIQPSPPWSYDQSYQYLGSIASPSV-HP 271
           A TP+    PR + + ST F+ QP+ +   T                Y G  ASPS+ H 
Sbjct: 531 AATPDRIRFPRGTASRST-FHGQPRERRTAT----------------YNGPPASPSLSHE 573

Query: 272 ATPISPGRASGMTTLSAELSSRLSTAPDLTA 302
           ATP+S  R+ G T L ++L+S+L+ + +++A
Sbjct: 574 ATPLSQTRSRGSTNLFSKLTSKLTRSRNVSA 604


>gi|46852166 MAP/microtubule affinity-regulating kinase 3 isoform c
           [Homo sapiens]
          Length = 729

 Score = 37.0 bits (84), Expect = 0.037
 Identities = 30/91 (32%), Positives = 48/91 (52%), Gaps = 22/91 (24%)

Query: 217 APTPN----PRASLNHSTAFNPQPQSQMQDTRQIQPSPPWSYDQSYQYLGSIASPSV-HP 271
           A TP+    PR + + ST F+ QP+ +   T                Y G  ASPS+ H 
Sbjct: 547 AATPDRIRFPRGTASRST-FHGQPRERRTAT----------------YNGPPASPSLSHE 589

Query: 272 ATPISPGRASGMTTLSAELSSRLSTAPDLTA 302
           ATP+S  R+ G T L ++L+S+L+ + +++A
Sbjct: 590 ATPLSQTRSRGSTNLFSKLTSKLTRSRNVSA 620


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.129    0.386 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,815,760
Number of Sequences: 37866
Number of extensions: 1132171
Number of successful extensions: 4337
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 230
Number of HSP's that attempted gapping in prelim test: 4016
Number of HSP's gapped (non-prelim): 496
length of query: 453
length of database: 18,247,518
effective HSP length: 106
effective length of query: 347
effective length of database: 14,233,722
effective search space: 4939101534
effective search space used: 4939101534
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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