Guide to the Human Genome
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Search of human proteins with 49258196

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|49258196 syntaxin 19 [Homo sapiens]
         (294 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|49258196 syntaxin 19 [Homo sapiens]                                580   e-166
gi|33667038 syntaxin 11 [Homo sapiens]                                217   1e-56
gi|4759182 syntaxin 1A (brain) [Homo sapiens]                         149   3e-36
gi|16418379 syntaxin 1B [Homo sapiens]                                149   4e-36
gi|4759184 syntaxin 3 [Homo sapiens]                                  141   6e-34
gi|37577287 syntaxin 2 isoform 1 [Homo sapiens]                       140   1e-33
gi|37577162 syntaxin 2 isoform 2 [Homo sapiens]                       140   1e-33
gi|20149560 syntaxin 4 [Homo sapiens]                                 117   9e-27
gi|28933465 syntaxin 12 [Homo sapiens]                                 58   1e-08
gi|170932494 syntaxin 7 [Homo sapiens]                                 55   1e-07
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]                   51   1e-06
gi|63252902 tropomyosin 1 alpha chain isoform 2 [Homo sapiens]         50   2e-06
gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens]         48   9e-06
gi|100814339 coiled-coil domain containing 146 [Homo sapiens]          46   4e-05
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]         45   1e-04
gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens]         44   2e-04
gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]         44   2e-04
gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]         44   2e-04
gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]         44   2e-04
gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]         44   2e-04
gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens]         44   2e-04
gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens]         44   2e-04
gi|55749708 outer dense fiber of sperm tails 2-like isoform b [H...    44   2e-04
gi|55749696 outer dense fiber of sperm tails 2-like isoform a [H...    44   2e-04
gi|118498356 kinectin 1 isoform a [Homo sapiens]                       43   3e-04
gi|118498368 kinectin 1 isoform c [Homo sapiens]                       43   3e-04
gi|33620775 kinectin 1 isoform a [Homo sapiens]                        43   3e-04
gi|114155144 tropomyosin 3 isoform 4 [Homo sapiens]                    43   3e-04
gi|34878777 ring finger protein 20 [Homo sapiens]                      43   3e-04
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ...    43   4e-04

>gi|49258196 syntaxin 19 [Homo sapiens]
          Length = 294

 Score =  580 bits (1496), Expect = e-166
 Identities = 294/294 (100%), Positives = 294/294 (100%)

Query: 1   MKDRLQELKQRTKEIELSRDSHVSTTETEEQGVFLQQAVIYEREPVAERHLHEIQKLQES 60
           MKDRLQELKQRTKEIELSRDSHVSTTETEEQGVFLQQAVIYEREPVAERHLHEIQKLQES
Sbjct: 1   MKDRLQELKQRTKEIELSRDSHVSTTETEEQGVFLQQAVIYEREPVAERHLHEIQKLQES 60

Query: 61  INNLADNVQKFGQQQKSLVASMRRFSLLKRESTITKEIKIQAEYINRSLNDLVKEVKKSE 120
           INNLADNVQKFGQQQKSLVASMRRFSLLKRESTITKEIKIQAEYINRSLNDLVKEVKKSE
Sbjct: 61  INNLADNVQKFGQQQKSLVASMRRFSLLKRESTITKEIKIQAEYINRSLNDLVKEVKKSE 120

Query: 121 VENGPSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFILRQLEVAGKEMSEE 180
           VENGPSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFILRQLEVAGKEMSEE
Sbjct: 121 VENGPSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFILRQLEVAGKEMSEE 180

Query: 181 DVNDMLHQGKWEVFNESLLTEINITKAQLSEIEQRHKELVNLENQIKDLRDLFIQISLLV 240
           DVNDMLHQGKWEVFNESLLTEINITKAQLSEIEQRHKELVNLENQIKDLRDLFIQISLLV
Sbjct: 181 DVNDMLHQGKWEVFNESLLTEINITKAQLSEIEQRHKELVNLENQIKDLRDLFIQISLLV 240

Query: 241 EEQGESINNIEMTVNSTKEYVNNTKEKFGLAVKYKKRNPCRVLCCWCCPCCSSK 294
           EEQGESINNIEMTVNSTKEYVNNTKEKFGLAVKYKKRNPCRVLCCWCCPCCSSK
Sbjct: 241 EEQGESINNIEMTVNSTKEYVNNTKEKFGLAVKYKKRNPCRVLCCWCCPCCSSK 294


>gi|33667038 syntaxin 11 [Homo sapiens]
          Length = 287

 Score =  217 bits (552), Expect = 1e-56
 Identities = 108/291 (37%), Positives = 184/291 (63%), Gaps = 7/291 (2%)

Query: 1   MKDRLQELKQRTKEIELSRDSHVSTTETEEQGVFLQQAVIYEREPVAERHLHEIQKLQES 60
           MKDRL EL      ++LS+       + +++     + +++E + + E    +I+ +Q+ 
Sbjct: 1   MKDRLAEL------LDLSKQYDQQFPDGDDEFDSPHEDIVFETDHILESLYRDIRDIQDE 54

Query: 61  INNLADNVQKFGQQQKSLVASMRRFSLLKRES-TITKEIKIQAEYINRSLNDLVKEVKKS 119
              L  +V++ G+Q    + SMRR S +KR++ +I K IK + E I+  L  + +  + +
Sbjct: 55  NQLLVADVKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAA 114

Query: 120 EVENGPSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFILRQLEVAGKEMSE 179
           E ++GP S V RI ++Q+ A+   FQ+ M  YN     +++ CK  I RQLE+ GKE+S 
Sbjct: 115 EAQHGPHSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIMGKEVSG 174

Query: 180 EDVNDMLHQGKWEVFNESLLTEINITKAQLSEIEQRHKELVNLENQIKDLRDLFIQISLL 239
           + + DM  QGKW+VF+E+LL ++   +A L+EIE RH+EL+ LE++I+D+ +LF+Q+++L
Sbjct: 175 DQIEDMFEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELFLQMAVL 234

Query: 240 VEEQGESINNIEMTVNSTKEYVNNTKEKFGLAVKYKKRNPCRVLCCWCCPC 290
           VE+Q +++N IE+ V  T +Y    K +   AV+Y+++NPCR LCC+CCPC
Sbjct: 235 VEKQADTLNVIELNVQKTVDYTGQAKAQVRKAVQYEEKNPCRTLCCFCCPC 285


>gi|4759182 syntaxin 1A (brain) [Homo sapiens]
          Length = 288

 Score =  149 bits (376), Expect = 3e-36
 Identities = 88/283 (31%), Positives = 156/283 (55%), Gaps = 13/283 (4%)

Query: 8   LKQRTKEIELSRDSHVSTTETEEQGVFLQQAVIYEREPVAERHLHEIQKLQESINNLADN 67
           +K RT+E+  ++DS       ++  V    AV  +R+   +    ++++++  I+ +A+N
Sbjct: 1   MKDRTQELRTAKDSD------DDDDV----AVTVDRDRFMDEFFEQVEEIRGFIDKIAEN 50

Query: 68  VQKFGQQQKSLVASMRRFSLLKRE-STITKEIKIQAEYINRSLNDLVKEVKKSEVENGPS 126
           V++  ++  +++AS       K E   +  +IK  A  +   L  + + +++ E  N  S
Sbjct: 51  VEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNR-S 109

Query: 127 SVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFILRQLEVAGKEMSEEDVNDML 186
           S   RI K+QH+ + R F ++M  YN T +  +E+CK  I RQLE+ G+  + E++ DML
Sbjct: 110 SADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDML 169

Query: 187 HQGKWEVFNESLLTEINITKAQLSEIEQRHKELVNLENQIKDLRDLFIQISLLVEEQGES 246
             G   +F   ++ + +I+K  LSEIE RH E++ LEN I++L D+F+ +++LVE QGE 
Sbjct: 170 ESGNPAIFASGIIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEM 229

Query: 247 INNIEMTVNSTKEYVNNTKEKFGLAVKYK-KRNPCRVLCCWCC 288
           I+ IE  V    +YV         AVKY+ K    +++   CC
Sbjct: 230 IDRIEYNVEHAVDYVERAVSDTKKAVKYQSKARRKKIMIIICC 272


>gi|16418379 syntaxin 1B [Homo sapiens]
          Length = 288

 Score =  149 bits (375), Expect = 4e-36
 Identities = 86/283 (30%), Positives = 158/283 (55%), Gaps = 14/283 (4%)

Query: 8   LKQRTKEIELSRDSHVSTTETEEQGVFLQQAVIYEREPVAERHLHEIQKLQESINNLADN 67
           +K RT+E+  ++DS     + EE+ V +      +R+   +    ++++++  I  L+++
Sbjct: 1   MKDRTQELRSAKDS-----DDEEEVVHV------DRDHFMDEFFEQVEEIRGCIEKLSED 49

Query: 68  VQKFGQQQKSLVASMRRFSLLKRE-STITKEIKIQAEYINRSLNDLVKEVKKSEVENGPS 126
           V++  +Q  +++A+       K+E   +T +IK  A  +   L  + + +++ E  N  S
Sbjct: 50  VEQVKKQHSAILAAPNPDEKTKQELEDLTADIKKTANKVRSKLKAIEQSIEQEEGLNR-S 108

Query: 127 SVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFILRQLEVAGKEMSEEDVNDML 186
           S   RI K+QH+ + R F ++M  YN T +  +++CK  I RQLE+ G+  + E++ DML
Sbjct: 109 SADLRIRKTQHSTLSRKFVEVMTEYNATQSKYRDRCKDRIQRQLEITGRTTTNEELEDML 168

Query: 187 HQGKWEVFNESLLTEINITKAQLSEIEQRHKELVNLENQIKDLRDLFIQISLLVEEQGES 246
             GK  +F + +  +  +TK  L+EIE RH E++ LE  I++L D+F+ +++LVE QGE 
Sbjct: 169 ESGKLAIFTDDIKMDSQMTKQALNEIETRHNEIIKLETSIRELHDMFVDMAMLVESQGEM 228

Query: 247 INNIEMTVNSTKEYVNNTKEKFGLAVKYK-KRNPCRVLCCWCC 288
           I+ IE  V  + +YV         AVKY+ K    +++   CC
Sbjct: 229 IDRIEYNVEHSVDYVERAVSDTKKAVKYQSKARRKKIMIIICC 271


>gi|4759184 syntaxin 3 [Homo sapiens]
          Length = 289

 Score =  141 bits (356), Expect = 6e-34
 Identities = 86/278 (30%), Positives = 156/278 (56%), Gaps = 20/278 (7%)

Query: 1   MKDRLQELKQRTKEIELSRDSHVSTTETEEQGVFLQQAVIYEREPVAERHLHEIQKLQES 60
           MKDRL++LK +    +L++D      E           +  +     +    EI++ + +
Sbjct: 1   MKDRLEQLKAK----QLTQDDDTDAVE-----------IAIDNTAFMDEFFSEIEETRLN 45

Query: 61  INNLADNVQKFGQQQKSLVASMRRFSLLKRE-STITKEIKIQAEYINRSLNDLVKEVKKS 119
           I+ ++++V++  +    ++++       K +   +T EIK +A  +   L  + K +++ 
Sbjct: 46  IDKISEHVEEAKKLYSIILSAPIPEPKTKDDLEQLTTEIKKRANNVRNKLKSMEKHIEED 105

Query: 120 EVENGPSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFILRQLEVAGKEMSE 179
           EV    SS   RI KSQH+ + R F ++M  YN+     +E+ K  I RQLE+ GK+ ++
Sbjct: 106 EVR---SSADLRIRKSQHSVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEITGKKTTD 162

Query: 180 EDVNDMLHQGKWEVFNESLLTEINITKAQLSEIEQRHKELVNLENQIKDLRDLFIQISLL 239
           E++ +ML  G   +F   ++ +  I+K  LSEIE RHK++V LE+ IK+L D+F+ I++L
Sbjct: 163 EELEEMLESGNPAIFTSGII-DSQISKQALSEIEGRHKDIVRLESSIKELHDMFMDIAML 221

Query: 240 VEEQGESINNIEMTVNSTKEYVNNTKEKFGLAVKYKKR 277
           VE QGE ++NIE+ V  T ++V   +++   AVKY+ +
Sbjct: 222 VENQGEMLDNIELNVMHTVDHVEKARDETKKAVKYQSQ 259


>gi|37577287 syntaxin 2 isoform 1 [Homo sapiens]
          Length = 287

 Score =  140 bits (353), Expect = 1e-33
 Identities = 73/240 (30%), Positives = 139/240 (57%), Gaps = 2/240 (0%)

Query: 39  VIYEREPVAERHLHEIQKLQESINNLADNVQKFGQQQKSLVASMRRFSLLKRE-STITKE 97
           V+ E++   +   H++++++ SI+ +   V++  +    ++++      +K E   + KE
Sbjct: 21  VVVEKDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKE 80

Query: 98  IKIQAEYINRSLNDLVKEVKKSEVENGPSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAA 157
           IK  A  I   L  + +   + E  N  +SV  RI ++QH+ + R F + M  YN+    
Sbjct: 81  IKKTANKIRAKLKAIEQSFDQDESGNR-TSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTL 139

Query: 158 KQEKCKTFILRQLEVAGKEMSEEDVNDMLHQGKWEVFNESLLTEINITKAQLSEIEQRHK 217
            +E+ K  I RQLE+ G+  +++++ +ML  GK  +F   ++++  IT+  L+EIE RHK
Sbjct: 140 FRERSKGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSDIISDSQITRQALNEIESRHK 199

Query: 218 ELVNLENQIKDLRDLFIQISLLVEEQGESINNIEMTVNSTKEYVNNTKEKFGLAVKYKKR 277
           +++ LE  I++L ++F+ +++ VE QGE INNIE  V +  +YV + KE+   A+KY+ +
Sbjct: 200 DIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQSK 259


>gi|37577162 syntaxin 2 isoform 2 [Homo sapiens]
          Length = 288

 Score =  140 bits (353), Expect = 1e-33
 Identities = 73/240 (30%), Positives = 139/240 (57%), Gaps = 2/240 (0%)

Query: 39  VIYEREPVAERHLHEIQKLQESINNLADNVQKFGQQQKSLVASMRRFSLLKRE-STITKE 97
           V+ E++   +   H++++++ SI+ +   V++  +    ++++      +K E   + KE
Sbjct: 21  VVVEKDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKE 80

Query: 98  IKIQAEYINRSLNDLVKEVKKSEVENGPSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAA 157
           IK  A  I   L  + +   + E  N  +SV  RI ++QH+ + R F + M  YN+    
Sbjct: 81  IKKTANKIRAKLKAIEQSFDQDESGNR-TSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTL 139

Query: 158 KQEKCKTFILRQLEVAGKEMSEEDVNDMLHQGKWEVFNESLLTEINITKAQLSEIEQRHK 217
            +E+ K  I RQLE+ G+  +++++ +ML  GK  +F   ++++  IT+  L+EIE RHK
Sbjct: 140 FRERSKGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSDIISDSQITRQALNEIESRHK 199

Query: 218 ELVNLENQIKDLRDLFIQISLLVEEQGESINNIEMTVNSTKEYVNNTKEKFGLAVKYKKR 277
           +++ LE  I++L ++F+ +++ VE QGE INNIE  V +  +YV + KE+   A+KY+ +
Sbjct: 200 DIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQSK 259


>gi|20149560 syntaxin 4 [Homo sapiens]
          Length = 297

 Score =  117 bits (294), Expect = 9e-27
 Identities = 84/283 (29%), Positives = 145/283 (51%), Gaps = 7/283 (2%)

Query: 8   LKQRTKEIELSRDSHVSTTETEEQGVFLQQAVIYEREPVAERHLHEIQKLQESINNLADN 67
           ++ RT E+    DS  S  E +E+   +            E   H+++ ++++I  L + 
Sbjct: 1   MRDRTHELRQGDDS--SDEEDKERVALVVHPGTARLGSPDEEFFHKVRTIRQTIVKLGNK 58

Query: 68  VQKFGQQQKSLVASMRRFSLLKRE-STITKEIKIQAEYINRSLNDLVKEVKKSEVENGPS 126
           VQ+  +QQ +++A+      +K+E   +  EIK     I   L  +  E +K E +   +
Sbjct: 59  VQELEKQQVTILATPLPEESMKQELQNLRDEIKQLGREIRLQLKAI--EPQKEEADENYN 116

Query: 127 SVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFILRQLEVAGKEM-SEEDVNDM 185
           SV TR+ K+QH  + + F +++   N   +  +EK    I RQL++    M S+E++  M
Sbjct: 117 SVNTRMRKTQHGVLSQQFVELINKCNSMQSEYREKNVERIRRQLKITNAGMVSDEELEQM 176

Query: 186 LHQGKWEVFNESLLTEINITKAQLSEIEQRHKELVNLENQIKDLRDLFIQISLLVEEQGE 245
           L  G+ EVF  ++L +  +T+  L+EI  RH E+  LE  I++L D+F  ++  VE QGE
Sbjct: 177 LDSGQSEVFVSNILKDTQVTRQALNEISARHSEIQQLERSIRELHDIFTFLATEVEMQGE 236

Query: 246 SINNIEMTVNSTKEYVNNTKEKFGLAVK-YKKRNPCRVLCCWC 287
            IN IE  + S+ +YV   +E    A++  KK    +VL   C
Sbjct: 237 MINRIEKNILSSADYVERGQEHVKTALENQKKARKKKVLIAIC 279


>gi|28933465 syntaxin 12 [Homo sapiens]
          Length = 276

 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 53/236 (22%), Positives = 104/236 (44%), Gaps = 16/236 (6%)

Query: 53  EIQKLQESINNLADNVQKFGQQQKSLVASMRRFSLLKRESTITKEIKIQAEYINRSLNDL 112
           +++     I   + N+Q+  Q    +   M +    +  S + + +    + +  S N L
Sbjct: 18  QLRDFSSIIQTCSGNIQRISQATAQIKNLMSQLGTKQDSSKLQENL----QQLQHSTNQL 73

Query: 113 VKEVKKSEVENG--PSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQ---EKCKTFIL 167
            KE  +   E G  P  + T   + Q     R         N+  A ++   EK K  I 
Sbjct: 74  AKETNELLKELGSLPLPLSTSEQRQQRLQKERLMNDFSAALNNFQAVQRRVSEKEKESIA 133

Query: 168 R-----QLEVAGKEMSEEDVNDMLHQGKWEVFNESLLTEINITKAQLSEIEQRHKELVNL 222
           R     +L    ++  E+ V+   H+ +W    +S   E+ IT+  L  I++R   +  L
Sbjct: 134 RARAGSRLSAEERQREEQLVSFDSHE-EWNQM-QSQEDEVAITEQDLELIKERETAIRQL 191

Query: 223 ENQIKDLRDLFIQISLLVEEQGESINNIEMTVNSTKEYVNNTKEKFGLAVKYKKRN 278
           E  I D+  +F  +++++ +QG+ I++IE  V S++ +V    E+   A  Y+K++
Sbjct: 192 EADILDVNQIFKDLAMMIHDQGDLIDSIEANVESSEVHVERATEQLQRAAYYQKKS 247


>gi|170932494 syntaxin 7 [Homo sapiens]
          Length = 261

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 43/225 (19%), Positives = 98/225 (43%), Gaps = 7/225 (3%)

Query: 64  LADNVQKFGQQQKSLVASMRRFSLLKRESTITKEIKIQAEYINRSLNDLVKEVKK-SEVE 122
           ++ N+QK  Q    +  ++ +    +    + ++++ + +Y N+   +  K +K+   + 
Sbjct: 18  ISSNIQKITQCSVEIQRTLNQLGTPQDSPELRQQLQQKQQYTNQLAKETDKYIKEFGSLP 77

Query: 123 NGPSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFILR---QLEVAGKEMSE 179
             PS    R  K Q   +   F   +  +        E+ K F+ R      V+G    +
Sbjct: 78  TTPSE--QRQRKIQKDRLVAEFTTSLTNFQKVQRQAAEREKEFVARVRASSRVSGSFPED 135

Query: 180 EDVNDMLHQGKWEVFNESLLTEINITKAQLSEIEQRHKELVNLENQIKDLRDLFIQISLL 239
                 L   + +   +  + +  IT+  L  I +R   +  LE  I D+ ++F  + ++
Sbjct: 136 SSKERNLVSWESQTQPQVQVQDEEITEDDLRLIHERESSIRQLEADIMDINEIFKDLGMM 195

Query: 240 VEEQGESINNIEMTVNSTKEYVNNTKEKFGLAVKYKKRNPCRVLC 284
           + EQG+ I++IE  V + + +V    ++   A  Y++++  + LC
Sbjct: 196 IHEQGDVIDSIEANVENAEVHVQQANQQLSRAADYQRKSR-KTLC 239


>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
          Length = 1417

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 64/288 (22%), Positives = 126/288 (43%), Gaps = 63/288 (21%)

Query: 6    QELKQRTKEI-----ELSRDSHVSTTETEEQGVFLQ-----QAVIYEREPVAERHLHEIQ 55
            ++LK++++E+     EL   +H S  ET EQ V LQ     Q  + ++E +    L + Q
Sbjct: 874  KQLKKKSEEVYCLQKELKIKNH-SLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQ 932

Query: 56   -KLQESINNLADNVQKFGQQQKSLVASMRRFSL----------LKRESTI-----TKEIK 99
             KL++ ++ L   +QK   Q++S    +R+             LKR+  I      +++K
Sbjct: 933  TKLEKQVSKLEQELQK---QRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVK 989

Query: 100  IQAEYINRSLNDLVKEVKKSEVENGPSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQ 159
            I+ +     L+ + KE+                LK        H  Q+  I + T    +
Sbjct: 990  IEMDQYKEELSKMEKEIMH--------------LKRDGENKAMHLSQLDMILDQTKTELE 1035

Query: 160  EKCKTFILRQLEVAGKEMSEEDVNDMLHQGKWEVFNESLLTEINITKAQLSEIEQRHKEL 219
            +K  T  +++LE   +  +E ++ + L   K EV                +E++  H EL
Sbjct: 1036 KK--TNAVKELEKL-QHSTETELTEALQ--KREVLE--------------TELQNAHGEL 1076

Query: 220  VNLENQIKDLRDLFIQISLLVEEQGESINNIEMTVNSTKEYVNNTKEK 267
             +   Q+++LRD+  +  L +EE+  +I ++   +   K  + + K++
Sbjct: 1077 KSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQE 1124



 Score = 38.9 bits (89), Expect = 0.005
 Identities = 56/294 (19%), Positives = 116/294 (39%), Gaps = 55/294 (18%)

Query: 1    MKDRLQELKQRTKEIELSRDSHVSTTETEEQGVFLQQAVIYEREPVAERHLHEIQKLQES 60
            +K+R  ELKQR  ++     +H+  T  E +G   Q+  I + E   E+   E+++  + 
Sbjct: 1132 LKERNWELKQRAAQV-----THLDMTIREHRGEMEQK--IIKLEGTLEKSELELKECNKQ 1184

Query: 61   INNLADNVQKFGQQQKS----LVASMRRFSLLKRESTITKEIKIQAEYINRSLNDLVKEV 116
            I +L D +Q   +Q +     ++ + +  S LK+E   T++   + E + +     +   
Sbjct: 1185 IESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQ 1244

Query: 117  KKSEVENGPSSVVTRI-LKSQHA--AMFRHFQQIM------------------------- 148
             K  ++ G    +TR  +++ H   A  RH QQ+                          
Sbjct: 1245 YKEAIDLGQELRLTREQVQNSHTELAEARH-QQVQAQREIERLSSELEDMKQLSKEKDAH 1303

Query: 149  --FIYNDTIAAKQEKCKTFILRQLEVAGKEMSEEDVNDMLHQ---------GKWEVFNES 197
               +  +  A+K  +       Q E+       E + +  H           KW++  +S
Sbjct: 1304 GNHLAEELGASKVREAHLEARMQAEIKKLSAEVESLKEAYHMEMISHQENHAKWKISADS 1363

Query: 198  LLTEINITKAQLS----EIEQRHKELVNLENQIKDLRDLFIQISLLVEEQGESI 247
              + +     QL     E+E+    + NL  Q++D  ++    +  +  +GE++
Sbjct: 1364 QKSSVQQLNEQLEKAKLELEEAQDTVSNLHQQVQDRNEVIEAANEALLTKGENV 1417


>gi|63252902 tropomyosin 1 alpha chain isoform 2 [Homo sapiens]
          Length = 284

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 54/275 (19%), Positives = 114/275 (41%), Gaps = 20/275 (7%)

Query: 1   MKDRLQELK-------QRTKEIELSRDSHVSTTETEEQGVFLQQAVIYEREPVAERHLHE 53
           +K ++Q LK        R ++ E  + +    ++  E+ +  ++ ++   E   +R L E
Sbjct: 4   IKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRVLEE 63

Query: 54  IQKLQESINNLADNVQKFGQQQKSLVASMRRFSLLKRESTITKEIKIQAEYINRSLNDLV 113
           + K ++S+            ++ +  A     SL +R   + +E+    E +  +L  L 
Sbjct: 64  LHKAEDSL---------LAAEEAAAKAEADVASLNRRIQLVEEELDRAQERLATALQKLE 114

Query: 114 KEVKKS-EVENGPSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFILRQLEV 172
           +  K + E E G   + +R  K +        Q+I       IA   ++    + R+L +
Sbjct: 115 EAEKAADESERGMKVIESRAQKDEEKM---EIQEIQLKEAKHIAEDADRKYEEVARKLVI 171

Query: 173 AGKEMSEEDVNDMLHQGKWEVFNESLLTEINITKAQLSEIEQRHKELVNLENQIKDLRDL 232
              ++   +    L +GK     E L T  N  K+  ++ E+  ++    E +IK L D 
Sbjct: 172 IESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDK 231

Query: 233 FIQISLLVEEQGESINNIEMTVNSTKEYVNNTKEK 267
             +     E    S+  +E +++  +E V + KE+
Sbjct: 232 LKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEE 266


>gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens]
          Length = 284

 Score = 48.1 bits (113), Expect = 9e-06
 Identities = 51/276 (18%), Positives = 113/276 (40%), Gaps = 23/276 (8%)

Query: 5   LQELKQRTKEIELSRDSHVSTTETEEQGVFLQQAVIYEREPVAERHLHEIQKLQESINNL 64
           +  +K++ + ++L +++ +   E  E      +    +R    E    E+  LQ+ +   
Sbjct: 1   MDAIKKKMQMLKLDKENALDRAEQAEA----DKKAAEDRSKQLE---DELVSLQKKLKGT 53

Query: 65  ADNVQKFGQ-----QQKSLVASMRRFSLLKRESTITKEIKIQAEYINRSLNDLVKEVKK- 118
            D + K+ +     Q+K  +A  +        +++ + I++  E ++R+   L   ++K 
Sbjct: 54  EDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKL 113

Query: 119 -------SEVENGPSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFILRQLE 171
                   E E G   + +R  K +        Q+I       IA   ++    + R+L 
Sbjct: 114 EEAEKAADESERGMKVIESRAQKDEEKM---EIQEIQLKEAKHIAEDADRKYEEVARKLV 170

Query: 172 VAGKEMSEEDVNDMLHQGKWEVFNESLLTEINITKAQLSEIEQRHKELVNLENQIKDLRD 231
           +   ++   +    L +GK     E L T  N  K+  ++ E+  ++    E +IK L D
Sbjct: 171 IIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSD 230

Query: 232 LFIQISLLVEEQGESINNIEMTVNSTKEYVNNTKEK 267
              +     E    S+  +E +++  +E V + KE+
Sbjct: 231 KLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEE 266


>gi|100814339 coiled-coil domain containing 146 [Homo sapiens]
          Length = 955

 Score = 45.8 bits (107), Expect = 4e-05
 Identities = 54/256 (21%), Positives = 117/256 (45%), Gaps = 40/256 (15%)

Query: 36  QQAVIYEREP-VAERHLHEIQKLQESINNLADNVQKFGQQQKSLVASMRRFSLLKRESTI 94
           QQ +I E E  + E+ L E  KL +   N+           K LV ++ R + +K +   
Sbjct: 422 QQKIISEMESKLVEQQLAEENKLLKEQENM-----------KELVVNLLRMTQIKIDEKE 470

Query: 95  TKE---IKIQAEYINRSLNDLVKEVKKSEVENGPSSVVTRILKSQHAAMFRHFQQIMFIY 151
            K    +K Q +Y N     +VKE+K  ++E        RI K +   ++R  ++   +Y
Sbjct: 471 QKSKDFLKAQQKYTN-----IVKEMKAKDLE-------IRIHKKKKCEIYRRLREFAKLY 518

Query: 152 NDTIAAKQEKCKTFILRQLEVAGKEMSEEDVNDMLHQGKWEVFNESLLTEINITKAQLSE 211
            DTI  ++ K     +  L  A ++++E      +   + E+   S +++    + +L  
Sbjct: 519 -DTIRNERNK----FVNLLHKAHQKVNEIKERHKMSLNELEILRNSAVSQ----ERKLQN 569

Query: 212 IEQRHKELVNL-ENQIKDLRDLFIQISLLVEEQGESINNIEM---TVNSTKEYVNNTKEK 267
              +H   V + E+   D+R +  ++  + E++   +NNI+    T+   +E +   +++
Sbjct: 570 SMLKHANNVTIRESMQNDVRKIVSKLQEMKEKKEAQLNNIDRLANTITMIEEEMVQLRKR 629

Query: 268 FGLAVKYKKRNPCRVL 283
           +  AV+++  +  +++
Sbjct: 630 YEKAVQHRNESGVQLI 645


>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
          Length = 3907

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 56/278 (20%), Positives = 108/278 (38%), Gaps = 63/278 (22%)

Query: 7    ELKQRTKEIELSRDSHVSTTETEEQGVFLQQAVIYEREPVAERHLHEIQKLQESINNLAD 66
            E ++ T+ ++L + +     + E+   FL +  I +RE   +    EIQKL++ +  +  
Sbjct: 2041 EQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAI-DREHERDVFQQEIQKLEQQLK-VVP 2098

Query: 67   NVQKFGQQQKSLVASMRRFSLLKRESTITKEIKIQAEYINRSLNDLVKEVKKSEVENGPS 126
              Q   + Q   V  +     LK ++    E+ +  E + R + +  +E++K E      
Sbjct: 2099 RFQPISEHQTREVEQLANH--LKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFR---- 2152

Query: 127  SVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFILRQLEVAGKEMSEEDVNDML 186
                           R  +Q + +  DT                         + V D  
Sbjct: 2153 --------------VRELEQALLVSADTF------------------------QKVEDRK 2174

Query: 187  HQGKWEVFNESLLTEINITKAQLSEIEQRHKELVNLENQIKDLRD-----------LFIQ 235
            H G  E   E L  E+ + +A+   I+++ KE+ NLE Q++  R+           L +Q
Sbjct: 2175 HFGAVEAKPE-LSLEVQL-QAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQ 2232

Query: 236  ISLLVEEQGESINNIEMTVNSTKEYVNNTKEKFGLAVK 273
            + +  +E    +  +E       +   +  EK GLA+K
Sbjct: 2233 LEIQKKESTTRLQELE----QENKLFKDDMEKLGLAIK 2266



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 61/245 (24%), Positives = 111/245 (45%), Gaps = 24/245 (9%)

Query: 8    LKQRTKEIELSRDSHVSTTETEEQGVFLQQAVIYEREPVAERHLHEIQKLQESINNLADN 67
            LK   K +E     H   ++ EE+ +FL       ++ V E+   EI+ L E   +L   
Sbjct: 780  LKDEKKTLEDMLKIHTPVSQ-EERLIFLDSIKSKSKDSVWEK---EIEILIEENEDLK-- 833

Query: 68   VQKFGQQQKSLVASMRRFSLLKRESTITKEIKIQAEY--INRSLNDLVKEVKKSEVENGP 125
             Q+  Q  + +      FS  ++   +  + ++Q EY  + +  +DL     K E+E   
Sbjct: 834  -QQCIQLNEEIEKQRNTFSFAEKNFEVNYQ-ELQEEYACLLKVKDDLEDSKNKQELEYKS 891

Query: 126  SSVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFILRQLEVAGKEMSEEDVNDM 185
                   LK+ +  +  H Q+I        ++  ++ KTF+   LE+   E+ E+D  ++
Sbjct: 892  K------LKALNEEL--HLQRINPTTVKMKSSVFDEDKTFVAETLEMG--EVVEKDTTEL 941

Query: 186  LHQGKWEVFNESLLTEINITKAQLSE-IEQRHKELVNLENQIKDLRDLFIQISLLVEEQG 244
            +   K EV     L E++   + LSE ++Q+H E+  L  ++K L+    Q+SL   E  
Sbjct: 942  ME--KLEVTKREKL-ELSQRLSDLSEQLKQKHGEISFLNEEVKSLKQEKEQVSLRCRELE 998

Query: 245  ESINN 249
              IN+
Sbjct: 999  IIINH 1003



 Score = 34.3 bits (77), Expect = 0.13
 Identities = 59/272 (21%), Positives = 109/272 (40%), Gaps = 25/272 (9%)

Query: 6    QELKQRTKEIELSRDSHVS----TTETEEQGVFLQQ----AVIYEREPVAERHLHEI-QK 56
            QEL+ ++K   L+ + H+     TT   +  VF +     A   E   V E+   E+ +K
Sbjct: 885  QELEYKSKLKALNEELHLQRINPTTVKMKSSVFDEDKTFVAETLEMGEVVEKDTTELMEK 944

Query: 57   LQESINNLADNVQKFGQQQKSLVASMRRFSLLKRESTITKEIKIQAEYINRSLNDLVKEV 116
            L+ +     +  Q+     + L       S L  E    K+ K Q     R L  ++   
Sbjct: 945  LEVTKREKLELSQRLSDLSEQLKQKHGEISFLNEEVKSLKQEKEQVSLRCRELEIIINHN 1004

Query: 117  KKSEVENGPSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFILRQLEVAGKE 176
            +   V++  + V + +L        R  +  +   N +     E+ K  +  ++      
Sbjct: 1005 RAENVQSCDTQV-SSLLDGVVTMTSRGAEGSVSKVNKSFG---EESKIMVEDKVSFENMT 1060

Query: 177  MSEEDVNDMLHQGKWEVFNESLLTEINITKAQLSEIEQRHKELVNLENQIKDLRDLFIQI 236
            + EE   + L          S+  E ++   Q SE ++  KEL  L+++  DLR      
Sbjct: 1061 VGEESKQEQLILDHLP----SVTKESSLRATQPSENDKLQKELNVLKSEQNDLR------ 1110

Query: 237  SLLVEEQGESINNIEMT-VNSTKEYVNNTKEK 267
             L +E Q   ++ +  T V+  +EY+ N K+K
Sbjct: 1111 -LQMEAQRICLSLVYSTHVDQVREYMENEKDK 1141



 Score = 28.1 bits (61), Expect = 9.6
 Identities = 44/268 (16%), Positives = 110/268 (41%), Gaps = 40/268 (14%)

Query: 37   QAVIYEREPVAERHLHEIQKLQESINNLADNVQKFGQQQKSLVASMRRFSLLKRESTITK 96
            + ++ ++E V      EI++L E I  L   +   GQ+      SM   SL +   ++  
Sbjct: 2332 ECLMSDQECVKRNREEEIEQLNEVIEKLQQELANIGQK-----TSMNAHSLSEEADSLKH 2386

Query: 97   EIKIQAEYINRSLNDLVKEVKKSEVENGPSSVVTRILKSQHAAMFRHFQQIMFIYNDTIA 156
            ++ +        + + +   ++ E  N   + +  +LK  +  M +  Q++  +  +  +
Sbjct: 2387 QLDV-------VIAEKLALEQQVETANEEMTFMKNVLKETNFKMNQLTQELFSLKRERES 2439

Query: 157  AKQEKCKTFILRQLEVAGKEMS-----------EEDVNDMLHQGKWEVFNESLLTEINIT 205
               EK ++     + VA   +S           E+ +  + +Q  ++ F E+    I   
Sbjct: 2440 V--EKIQSIPENSVNVAIDHLSKDKPELEVVLTEDALKSLENQTYFKSFEENGKGSIINL 2497

Query: 206  KAQLSEIEQ----RHKELVNLENQIKDLRD-----------LFIQISLLVEEQGESINNI 250
            + +L ++E     +  EL     QIKD+++             + +  +VEE+  +    
Sbjct: 2498 ETRLLQLESTVSAKDLELTQCYKQIKDMQEQGQFETEMLQKKIVNLQKIVEEKVAAALVS 2557

Query: 251  EMTVNSTKEYVNNTKEKFGLAVKYKKRN 278
            ++ + + +EY    ++   ++ + ++ N
Sbjct: 2558 QIQLEAVQEYAKFCQDNQTISSEPERTN 2585


>gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens]
          Length = 284

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 49/277 (17%), Positives = 112/277 (40%), Gaps = 23/277 (8%)

Query: 5   LQELKQRTKEIELSRDSHVSTTETEEQGVFLQQAVIYEREPVAERHLHEIQKLQESINNL 64
           +  +K++ + ++L +++ +   E  E      +    +R    E    E+  LQ+ +   
Sbjct: 1   MDAIKKKMQMLKLDKENALDRAEQAEA----DKKAAEDRSKQLE---DELVSLQKKLKGT 53

Query: 65  ADNVQKFGQ-----QQKSLVASMRRFSLLKRESTITKEIKIQAEYINRSLNDLVKEVKK- 118
            D + K+ +     Q+K  +A  +        +++ + I++  E ++R+   L   ++K 
Sbjct: 54  EDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKL 113

Query: 119 -------SEVENGPSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFILRQLE 171
                   E E G   + +R  K +        Q+I       IA   ++    + R+L 
Sbjct: 114 EEAEKAADESERGMKVIESRAQKDEEKM---EIQEIQLKEAKHIAEDADRKYEEVARKLV 170

Query: 172 VAGKEMSEEDVNDMLHQGKWEVFNESLLTEINITKAQLSEIEQRHKELVNLENQIKDLRD 231
           +   ++   +    L +GK     E L T  N  K+  ++ E+  ++    E +IK L D
Sbjct: 171 IIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSD 230

Query: 232 LFIQISLLVEEQGESINNIEMTVNSTKEYVNNTKEKF 268
              +     E    S+  +E +++  ++ +   K K+
Sbjct: 231 KLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKY 267


>gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]
          Length = 983

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 57/273 (20%), Positives = 118/273 (43%), Gaps = 53/273 (19%)

Query: 7   ELKQRTKEIELSRDSHVSTTETEEQGV-----FLQQAVIYEREPVAERHLHEIQKLQESI 61
           EL+   +EI + +    +  E  E+         ++ V  E+  V +  + E ++++ S 
Sbjct: 527 ELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSY 586

Query: 62  NNLADNVQK-----FGQQQKSLVASMRRFSLLKRESTITKEIKIQAEYINRSLNDLVKEV 116
            ++ +N+ K     F + Q++    M+    LK  S +T+E   +AE +  ++N ++ E+
Sbjct: 587 CSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLK--SQMTQEASDEAEDMKEAMNRMIDEL 644

Query: 117 KKSEVENGPSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFILRQLEVAGKE 176
            K   E      ++++ K   A                              +LE   K 
Sbjct: 645 NKQVSE------LSQLYKEAQA------------------------------ELEDYRKR 668

Query: 177 MSEEDVN-DMLHQGKWEVFNESLLTEINITKAQ--LSEIEQRHKELVNLENQIKDLRDLF 233
            S EDV  + +H+ + E   +  LT ++  KA+  LSE++ ++ +++N   Q+K L D  
Sbjct: 669 KSLEDVTAEYIHKAEHEKLMQ--LTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQ 726

Query: 234 IQISLLVEEQGESINNIEMTVNSTKEYVNNTKE 266
            + S+ + E  + I  +       +E ++N KE
Sbjct: 727 KENSVSITEHLQVITTLRTAAKEMEEKISNLKE 759



 Score = 36.6 bits (83), Expect = 0.027
 Identities = 59/314 (18%), Positives = 120/314 (38%), Gaps = 79/314 (25%)

Query: 8   LKQRTKEIELSRDSHVSTTETEEQGVFLQQAVIYEREPVAERHL---------------- 51
           +K   +E E  + S+ S  E   +    ++A ++E+   A+  +                
Sbjct: 572 IKPPVEEYEEMKSSYCSVIENMNK----EKAFLFEKYQEAQEEIMKLKDTLKSQMTQEAS 627

Query: 52  HEIQKLQESINNLADNVQK----FGQQQKSLVASMRRFSLLKRESTITKEIKIQAEYINR 107
            E + ++E++N + D + K      Q  K   A +  +   K    +T      AEYI++
Sbjct: 628 DEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVT------AEYIHK 681

Query: 108 SLNDLVKEVKKSEVENGPSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTF-- 165
           + ++  K ++ + V    +      +KSQ++ +     Q+       + A++E   +   
Sbjct: 682 AEHE--KLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQL----KQLVDAQKENSVSITE 735

Query: 166 ---ILRQLEVAGKEMSEEDVN----------------------------DMLHQGKWEVF 194
              ++  L  A KEM E+  N                             M+ +  +E  
Sbjct: 736 HLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKL 795

Query: 195 NESLLTEINITKAQLSEIEQRHKELVNLENQIKDLRDLFIQISLLVEEQGESINNIEMTV 254
             SL +E+++  ++L E   + KE V+ E          +QI   V +      NI+  +
Sbjct: 796 QSSLESEVSVLASKLKE-SVKEKEKVHSE---------VVQIRSEVSQVKREKENIQTLL 845

Query: 255 NSTKEYVNNTKEKF 268
            S ++ VN   +KF
Sbjct: 846 KSKEQEVNELLQKF 859


>gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]
          Length = 972

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 57/273 (20%), Positives = 118/273 (43%), Gaps = 53/273 (19%)

Query: 7   ELKQRTKEIELSRDSHVSTTETEEQGV-----FLQQAVIYEREPVAERHLHEIQKLQESI 61
           EL+   +EI + +    +  E  E+         ++ V  E+  V +  + E ++++ S 
Sbjct: 516 ELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSY 575

Query: 62  NNLADNVQK-----FGQQQKSLVASMRRFSLLKRESTITKEIKIQAEYINRSLNDLVKEV 116
            ++ +N+ K     F + Q++    M+    LK  S +T+E   +AE +  ++N ++ E+
Sbjct: 576 CSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLK--SQMTQEASDEAEDMKEAMNRMIDEL 633

Query: 117 KKSEVENGPSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFILRQLEVAGKE 176
            K   E      ++++ K   A                              +LE   K 
Sbjct: 634 NKQVSE------LSQLYKEAQA------------------------------ELEDYRKR 657

Query: 177 MSEEDVN-DMLHQGKWEVFNESLLTEINITKAQ--LSEIEQRHKELVNLENQIKDLRDLF 233
            S EDV  + +H+ + E   +  LT ++  KA+  LSE++ ++ +++N   Q+K L D  
Sbjct: 658 KSLEDVTAEYIHKAEHEKLMQ--LTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQ 715

Query: 234 IQISLLVEEQGESINNIEMTVNSTKEYVNNTKE 266
            + S+ + E  + I  +       +E ++N KE
Sbjct: 716 KENSVSITEHLQVITTLRTAAKEMEEKISNLKE 748



 Score = 36.6 bits (83), Expect = 0.027
 Identities = 59/314 (18%), Positives = 120/314 (38%), Gaps = 79/314 (25%)

Query: 8   LKQRTKEIELSRDSHVSTTETEEQGVFLQQAVIYEREPVAERHL---------------- 51
           +K   +E E  + S+ S  E   +    ++A ++E+   A+  +                
Sbjct: 561 IKPPVEEYEEMKSSYCSVIENMNK----EKAFLFEKYQEAQEEIMKLKDTLKSQMTQEAS 616

Query: 52  HEIQKLQESINNLADNVQK----FGQQQKSLVASMRRFSLLKRESTITKEIKIQAEYINR 107
            E + ++E++N + D + K      Q  K   A +  +   K    +T      AEYI++
Sbjct: 617 DEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVT------AEYIHK 670

Query: 108 SLNDLVKEVKKSEVENGPSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTF-- 165
           + ++  K ++ + V    +      +KSQ++ +     Q+       + A++E   +   
Sbjct: 671 AEHE--KLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQL----KQLVDAQKENSVSITE 724

Query: 166 ---ILRQLEVAGKEMSEEDVN----------------------------DMLHQGKWEVF 194
              ++  L  A KEM E+  N                             M+ +  +E  
Sbjct: 725 HLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKL 784

Query: 195 NESLLTEINITKAQLSEIEQRHKELVNLENQIKDLRDLFIQISLLVEEQGESINNIEMTV 254
             SL +E+++  ++L E   + KE V+ E          +QI   V +      NI+  +
Sbjct: 785 QSSLESEVSVLASKLKE-SVKEKEKVHSE---------VVQIRSEVSQVKREKENIQTLL 834

Query: 255 NSTKEYVNNTKEKF 268
            S ++ VN   +KF
Sbjct: 835 KSKEQEVNELLQKF 848


>gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]
          Length = 951

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 57/273 (20%), Positives = 118/273 (43%), Gaps = 53/273 (19%)

Query: 7   ELKQRTKEIELSRDSHVSTTETEEQGV-----FLQQAVIYEREPVAERHLHEIQKLQESI 61
           EL+   +EI + +    +  E  E+         ++ V  E+  V +  + E ++++ S 
Sbjct: 495 ELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSY 554

Query: 62  NNLADNVQK-----FGQQQKSLVASMRRFSLLKRESTITKEIKIQAEYINRSLNDLVKEV 116
            ++ +N+ K     F + Q++    M+    LK  S +T+E   +AE +  ++N ++ E+
Sbjct: 555 CSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLK--SQMTQEASDEAEDMKEAMNRMIDEL 612

Query: 117 KKSEVENGPSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFILRQLEVAGKE 176
            K   E      ++++ K   A                              +LE   K 
Sbjct: 613 NKQVSE------LSQLYKEAQA------------------------------ELEDYRKR 636

Query: 177 MSEEDVN-DMLHQGKWEVFNESLLTEINITKAQ--LSEIEQRHKELVNLENQIKDLRDLF 233
            S EDV  + +H+ + E   +  LT ++  KA+  LSE++ ++ +++N   Q+K L D  
Sbjct: 637 KSLEDVTAEYIHKAEHEKLMQ--LTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQ 694

Query: 234 IQISLLVEEQGESINNIEMTVNSTKEYVNNTKE 266
            + S+ + E  + I  +       +E ++N KE
Sbjct: 695 KENSVSITEHLQVITTLRTAAKEMEEKISNLKE 727



 Score = 36.6 bits (83), Expect = 0.027
 Identities = 59/314 (18%), Positives = 120/314 (38%), Gaps = 79/314 (25%)

Query: 8   LKQRTKEIELSRDSHVSTTETEEQGVFLQQAVIYEREPVAERHL---------------- 51
           +K   +E E  + S+ S  E   +    ++A ++E+   A+  +                
Sbjct: 540 IKPPVEEYEEMKSSYCSVIENMNK----EKAFLFEKYQEAQEEIMKLKDTLKSQMTQEAS 595

Query: 52  HEIQKLQESINNLADNVQK----FGQQQKSLVASMRRFSLLKRESTITKEIKIQAEYINR 107
            E + ++E++N + D + K      Q  K   A +  +   K    +T      AEYI++
Sbjct: 596 DEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVT------AEYIHK 649

Query: 108 SLNDLVKEVKKSEVENGPSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTF-- 165
           + ++  K ++ + V    +      +KSQ++ +     Q+       + A++E   +   
Sbjct: 650 AEHE--KLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQL----KQLVDAQKENSVSITE 703

Query: 166 ---ILRQLEVAGKEMSEEDVN----------------------------DMLHQGKWEVF 194
              ++  L  A KEM E+  N                             M+ +  +E  
Sbjct: 704 HLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKL 763

Query: 195 NESLLTEINITKAQLSEIEQRHKELVNLENQIKDLRDLFIQISLLVEEQGESINNIEMTV 254
             SL +E+++  ++L E   + KE V+ E          +QI   V +      NI+  +
Sbjct: 764 QSSLESEVSVLASKLKE-SVKEKEKVHSE---------VVQIRSEVSQVKREKENIQTLL 813

Query: 255 NSTKEYVNNTKEKF 268
            S ++ VN   +KF
Sbjct: 814 KSKEQEVNELLQKF 827


>gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]
          Length = 980

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 57/273 (20%), Positives = 118/273 (43%), Gaps = 53/273 (19%)

Query: 7   ELKQRTKEIELSRDSHVSTTETEEQGV-----FLQQAVIYEREPVAERHLHEIQKLQESI 61
           EL+   +EI + +    +  E  E+         ++ V  E+  V +  + E ++++ S 
Sbjct: 524 ELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSY 583

Query: 62  NNLADNVQK-----FGQQQKSLVASMRRFSLLKRESTITKEIKIQAEYINRSLNDLVKEV 116
            ++ +N+ K     F + Q++    M+    LK  S +T+E   +AE +  ++N ++ E+
Sbjct: 584 CSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLK--SQMTQEASDEAEDMKEAMNRMIDEL 641

Query: 117 KKSEVENGPSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFILRQLEVAGKE 176
            K   E      ++++ K   A                              +LE   K 
Sbjct: 642 NKQVSE------LSQLYKEAQA------------------------------ELEDYRKR 665

Query: 177 MSEEDVN-DMLHQGKWEVFNESLLTEINITKAQ--LSEIEQRHKELVNLENQIKDLRDLF 233
            S EDV  + +H+ + E   +  LT ++  KA+  LSE++ ++ +++N   Q+K L D  
Sbjct: 666 KSLEDVTAEYIHKAEHEKLMQ--LTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQ 723

Query: 234 IQISLLVEEQGESINNIEMTVNSTKEYVNNTKE 266
            + S+ + E  + I  +       +E ++N KE
Sbjct: 724 KENSVSITEHLQVITTLRTAAKEMEEKISNLKE 756



 Score = 36.6 bits (83), Expect = 0.027
 Identities = 59/314 (18%), Positives = 120/314 (38%), Gaps = 79/314 (25%)

Query: 8   LKQRTKEIELSRDSHVSTTETEEQGVFLQQAVIYEREPVAERHL---------------- 51
           +K   +E E  + S+ S  E   +    ++A ++E+   A+  +                
Sbjct: 569 IKPPVEEYEEMKSSYCSVIENMNK----EKAFLFEKYQEAQEEIMKLKDTLKSQMTQEAS 624

Query: 52  HEIQKLQESINNLADNVQK----FGQQQKSLVASMRRFSLLKRESTITKEIKIQAEYINR 107
            E + ++E++N + D + K      Q  K   A +  +   K    +T      AEYI++
Sbjct: 625 DEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVT------AEYIHK 678

Query: 108 SLNDLVKEVKKSEVENGPSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTF-- 165
           + ++  K ++ + V    +      +KSQ++ +     Q+       + A++E   +   
Sbjct: 679 AEHE--KLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQL----KQLVDAQKENSVSITE 732

Query: 166 ---ILRQLEVAGKEMSEEDVN----------------------------DMLHQGKWEVF 194
              ++  L  A KEM E+  N                             M+ +  +E  
Sbjct: 733 HLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKL 792

Query: 195 NESLLTEINITKAQLSEIEQRHKELVNLENQIKDLRDLFIQISLLVEEQGESINNIEMTV 254
             SL +E+++  ++L E   + KE V+ E          +QI   V +      NI+  +
Sbjct: 793 QSSLESEVSVLASKLKE-SVKEKEKVHSE---------VVQIRSEVSQVKREKENIQTLL 842

Query: 255 NSTKEYVNNTKEKF 268
            S ++ VN   +KF
Sbjct: 843 KSKEQEVNELLQKF 856


>gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens]
          Length = 980

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 57/273 (20%), Positives = 118/273 (43%), Gaps = 53/273 (19%)

Query: 7   ELKQRTKEIELSRDSHVSTTETEEQGV-----FLQQAVIYEREPVAERHLHEIQKLQESI 61
           EL+   +EI + +    +  E  E+         ++ V  E+  V +  + E ++++ S 
Sbjct: 524 ELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSY 583

Query: 62  NNLADNVQK-----FGQQQKSLVASMRRFSLLKRESTITKEIKIQAEYINRSLNDLVKEV 116
            ++ +N+ K     F + Q++    M+    LK  S +T+E   +AE +  ++N ++ E+
Sbjct: 584 CSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLK--SQMTQEASDEAEDMKEAMNRMIDEL 641

Query: 117 KKSEVENGPSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFILRQLEVAGKE 176
            K   E      ++++ K   A                              +LE   K 
Sbjct: 642 NKQVSE------LSQLYKEAQA------------------------------ELEDYRKR 665

Query: 177 MSEEDVN-DMLHQGKWEVFNESLLTEINITKAQ--LSEIEQRHKELVNLENQIKDLRDLF 233
            S EDV  + +H+ + E   +  LT ++  KA+  LSE++ ++ +++N   Q+K L D  
Sbjct: 666 KSLEDVTAEYIHKAEHEKLMQ--LTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQ 723

Query: 234 IQISLLVEEQGESINNIEMTVNSTKEYVNNTKE 266
            + S+ + E  + I  +       +E ++N KE
Sbjct: 724 KENSVSITEHLQVITTLRTAAKEMEEKISNLKE 756



 Score = 36.6 bits (83), Expect = 0.027
 Identities = 59/314 (18%), Positives = 120/314 (38%), Gaps = 79/314 (25%)

Query: 8   LKQRTKEIELSRDSHVSTTETEEQGVFLQQAVIYEREPVAERHL---------------- 51
           +K   +E E  + S+ S  E   +    ++A ++E+   A+  +                
Sbjct: 569 IKPPVEEYEEMKSSYCSVIENMNK----EKAFLFEKYQEAQEEIMKLKDTLKSQMTQEAS 624

Query: 52  HEIQKLQESINNLADNVQK----FGQQQKSLVASMRRFSLLKRESTITKEIKIQAEYINR 107
            E + ++E++N + D + K      Q  K   A +  +   K    +T      AEYI++
Sbjct: 625 DEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVT------AEYIHK 678

Query: 108 SLNDLVKEVKKSEVENGPSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTF-- 165
           + ++  K ++ + V    +      +KSQ++ +     Q+       + A++E   +   
Sbjct: 679 AEHE--KLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQL----KQLVDAQKENSVSITE 732

Query: 166 ---ILRQLEVAGKEMSEEDVN----------------------------DMLHQGKWEVF 194
              ++  L  A KEM E+  N                             M+ +  +E  
Sbjct: 733 HLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKL 792

Query: 195 NESLLTEINITKAQLSEIEQRHKELVNLENQIKDLRDLFIQISLLVEEQGESINNIEMTV 254
             SL +E+++  ++L E   + KE V+ E          +QI   V +      NI+  +
Sbjct: 793 QSSLESEVSVLASKLKE-SVKEKEKVHSE---------VVQIRSEVSQVKREKENIQTLL 842

Query: 255 NSTKEYVNNTKEKF 268
            S ++ VN   +KF
Sbjct: 843 KSKEQEVNELLQKF 856


>gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens]
          Length = 980

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 57/273 (20%), Positives = 118/273 (43%), Gaps = 53/273 (19%)

Query: 7   ELKQRTKEIELSRDSHVSTTETEEQGV-----FLQQAVIYEREPVAERHLHEIQKLQESI 61
           EL+   +EI + +    +  E  E+         ++ V  E+  V +  + E ++++ S 
Sbjct: 524 ELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSY 583

Query: 62  NNLADNVQK-----FGQQQKSLVASMRRFSLLKRESTITKEIKIQAEYINRSLNDLVKEV 116
            ++ +N+ K     F + Q++    M+    LK  S +T+E   +AE +  ++N ++ E+
Sbjct: 584 CSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLK--SQMTQEASDEAEDMKEAMNRMIDEL 641

Query: 117 KKSEVENGPSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFILRQLEVAGKE 176
            K   E      ++++ K   A                              +LE   K 
Sbjct: 642 NKQVSE------LSQLYKEAQA------------------------------ELEDYRKR 665

Query: 177 MSEEDVN-DMLHQGKWEVFNESLLTEINITKAQ--LSEIEQRHKELVNLENQIKDLRDLF 233
            S EDV  + +H+ + E   +  LT ++  KA+  LSE++ ++ +++N   Q+K L D  
Sbjct: 666 KSLEDVTAEYIHKAEHEKLMQ--LTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQ 723

Query: 234 IQISLLVEEQGESINNIEMTVNSTKEYVNNTKE 266
            + S+ + E  + I  +       +E ++N KE
Sbjct: 724 KENSVSITEHLQVITTLRTAAKEMEEKISNLKE 756



 Score = 36.6 bits (83), Expect = 0.027
 Identities = 59/314 (18%), Positives = 120/314 (38%), Gaps = 79/314 (25%)

Query: 8   LKQRTKEIELSRDSHVSTTETEEQGVFLQQAVIYEREPVAERHL---------------- 51
           +K   +E E  + S+ S  E   +    ++A ++E+   A+  +                
Sbjct: 569 IKPPVEEYEEMKSSYCSVIENMNK----EKAFLFEKYQEAQEEIMKLKDTLKSQMTQEAS 624

Query: 52  HEIQKLQESINNLADNVQK----FGQQQKSLVASMRRFSLLKRESTITKEIKIQAEYINR 107
            E + ++E++N + D + K      Q  K   A +  +   K    +T      AEYI++
Sbjct: 625 DEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVT------AEYIHK 678

Query: 108 SLNDLVKEVKKSEVENGPSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTF-- 165
           + ++  K ++ + V    +      +KSQ++ +     Q+       + A++E   +   
Sbjct: 679 AEHE--KLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQL----KQLVDAQKENSVSITE 732

Query: 166 ---ILRQLEVAGKEMSEEDVN----------------------------DMLHQGKWEVF 194
              ++  L  A KEM E+  N                             M+ +  +E  
Sbjct: 733 HLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKL 792

Query: 195 NESLLTEINITKAQLSEIEQRHKELVNLENQIKDLRDLFIQISLLVEEQGESINNIEMTV 254
             SL +E+++  ++L E   + KE V+ E          +QI   V +      NI+  +
Sbjct: 793 QSSLESEVSVLASKLKE-SVKEKEKVHSE---------VVQIRSEVSQVKREKENIQTLL 842

Query: 255 NSTKEYVNNTKEKF 268
            S ++ VN   +KF
Sbjct: 843 KSKEQEVNELLQKF 856


>gi|55749708 outer dense fiber of sperm tails 2-like isoform b [Homo
           sapiens]
          Length = 513

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 52/254 (20%), Positives = 112/254 (44%), Gaps = 30/254 (11%)

Query: 39  VIYEREPVA-ERHLHEIQKLQESINNLADNVQKFGQQQK-----SLV---ASMRRFSLLK 89
           V++ER  +   +   E  KL+E + +L   + K+  Q +     ++V   AS ++   LK
Sbjct: 53  VVHERLQIQIHKREAENDKLKEYVKSLETKIAKWNLQSRMNKNEAIVMKEASRQKTVALK 112

Query: 90  RESTITKEIKIQAEYINRSLNDLVKEVKKSEVENGPSSVVTRILKSQHAAMFRHFQQIMF 149
           + S + K+   + ++   ++  L  +++  E +   +   +   KS       H+++I+ 
Sbjct: 113 KASKVYKQ---RLDHFTGAIEKLTSQIRDQEAKLSETISASNAWKS-------HYEKIVI 162

Query: 150 IYNDTIAAKQEKCKTFI-----LRQLEVAGKEMSEEDVNDMLHQGKWEVFNESLLTEINI 204
              +     +   K  I     L+++E  GK   EE +  + H  ++E  NE+L  E   
Sbjct: 163 EKTELEVQIETMKKQIINLLEDLKKMEDHGKNSCEEILRKV-HSIEYE--NETLNLENTK 219

Query: 205 TKAQLSEIEQRHKELVNLENQIKDLRDLFIQISLLVEEQGESINNIEMTVNSTKEYVNNT 264
            K  L+ ++    E+V++EN++ +L+++  +   L+E     +  ++      K    N 
Sbjct: 220 LKTTLAALKD---EVVSVENELSELQEVEKKQKTLIEMYKTQVQKLQEAAEIVKSRCENL 276

Query: 265 KEKFGLAVKYKKRN 278
             K     K K +N
Sbjct: 277 LHKNNQITKTKNKN 290


>gi|55749696 outer dense fiber of sperm tails 2-like isoform a [Homo
           sapiens]
          Length = 644

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 52/254 (20%), Positives = 112/254 (44%), Gaps = 30/254 (11%)

Query: 39  VIYEREPVA-ERHLHEIQKLQESINNLADNVQKFGQQQK-----SLV---ASMRRFSLLK 89
           V++ER  +   +   E  KL+E + +L   + K+  Q +     ++V   AS ++   LK
Sbjct: 184 VVHERLQIQIHKREAENDKLKEYVKSLETKIAKWNLQSRMNKNEAIVMKEASRQKTVALK 243

Query: 90  RESTITKEIKIQAEYINRSLNDLVKEVKKSEVENGPSSVVTRILKSQHAAMFRHFQQIMF 149
           + S + K+   + ++   ++  L  +++  E +   +   +   KS       H+++I+ 
Sbjct: 244 KASKVYKQ---RLDHFTGAIEKLTSQIRDQEAKLSETISASNAWKS-------HYEKIVI 293

Query: 150 IYNDTIAAKQEKCKTFI-----LRQLEVAGKEMSEEDVNDMLHQGKWEVFNESLLTEINI 204
              +     +   K  I     L+++E  GK   EE +  + H  ++E  NE+L  E   
Sbjct: 294 EKTELEVQIETMKKQIINLLEDLKKMEDHGKNSCEEILRKV-HSIEYE--NETLNLENTK 350

Query: 205 TKAQLSEIEQRHKELVNLENQIKDLRDLFIQISLLVEEQGESINNIEMTVNSTKEYVNNT 264
            K  L+ ++    E+V++EN++ +L+++  +   L+E     +  ++      K    N 
Sbjct: 351 LKTTLAALKD---EVVSVENELSELQEVEKKQKTLIEMYKTQVQKLQEAAEIVKSRCENL 407

Query: 265 KEKFGLAVKYKKRN 278
             K     K K +N
Sbjct: 408 LHKNNQITKTKNKN 421


>gi|118498356 kinectin 1 isoform a [Homo sapiens]
          Length = 1357

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 61/310 (19%), Positives = 133/310 (42%), Gaps = 56/310 (18%)

Query: 6   QELKQRTKEIELSRDSHVSTTETEEQGV----FLQQAVIYEREPVAERHL---HEIQKLQ 58
           +++KQ    +   RD  +++ E E + +    FL +A + + + +A       HE++K+Q
Sbjct: 614 KQIKQTEDSLASERD-RLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQ 672

Query: 59  ESINNLADNVQKFGQQ-QKSLVASMRRFSLLKRESTITKE--IKIQAEYINRSLNDLVKE 115
           +S+    D ++   +Q Q  +   M  F +L  ++   K    K+Q     +   D+V++
Sbjct: 673 QSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQ 732

Query: 116 VKK-------------SEVENGPSSVVTR-----ILKSQHAAMFRHFQQIMFIYNDTI-- 155
           ++K               +E G   V T+      ++++++++ +  Q +    ND +  
Sbjct: 733 MEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSF 792

Query: 156 AAKQEKCKTFILRQ---------------LEVAGKEMSEEDVNDMLHQGKWEVFNESLLT 200
           A+  E+ K  I  +               L+VA KE + +D+   +   K E+ N     
Sbjct: 793 ASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGN----- 847

Query: 201 EINITKAQLSEIEQRHKELVNL----ENQIKDLRDLFIQISLLVEEQGESINNIEMTVNS 256
            + + KAQ   I  + +EL NL    E Q+  ++ +  +    +   G+ + +++    S
Sbjct: 848 -VQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENES 906

Query: 257 TKEYVNNTKE 266
            K +V    +
Sbjct: 907 LKAHVQEVAQ 916



 Score = 31.6 bits (70), Expect = 0.87
 Identities = 58/279 (20%), Positives = 114/279 (40%), Gaps = 32/279 (11%)

Query: 8    LKQRTKEIELSRDSHVSTTETEEQGVFLQQAVIYEREPVAERHLHEIQKLQESINNLADN 67
            L +  K++   +D  + + E   +   L+ A    +E   +    EI+ L+E I N    
Sbjct: 795  LVEELKKVIHEKDGKIKSVEELLEAELLKVA---NKEKTVQDLKQEIKALKEEIGN---- 847

Query: 68   VQKFGQQQKSLVASMRRF-SLLKRESTITKEIKIQAEYINRSLNDLVKEVKKSEVENGP- 125
            VQ    QQ S+ + ++   +LLK +      +K   E   + L +  K ++  + EN   
Sbjct: 848  VQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESL 907

Query: 126  ----SSVVTRILK-SQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFILRQLEVAGKEMSEE 180
                  V    LK +  A+ F   + ++    + +   +   K    R+ +++ K    +
Sbjct: 908  KAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKE---RESDLSSKTQLLQ 964

Query: 181  DVNDMLHQGKWEVFNESLLTEINITKAQ--------LSEIEQRHKELVNLENQIKDLRDL 232
            DV D     K ++     L + N  +A         L  I +R KE+  L N++  L+D 
Sbjct: 965  DVQDENKLFKSQI---EQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDA 1021

Query: 233  F----IQISLLVEEQGESINNIEMTVNSTKEYVNNTKEK 267
                  + + L E+  E++  +  T    ++ VN T ++
Sbjct: 1022 VEHQRKKNNDLREKNWEAMEALASTEKMLQDKVNKTSKE 1060


>gi|118498368 kinectin 1 isoform c [Homo sapiens]
          Length = 1300

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 61/310 (19%), Positives = 133/310 (42%), Gaps = 56/310 (18%)

Query: 6   QELKQRTKEIELSRDSHVSTTETEEQGV----FLQQAVIYEREPVAERHL---HEIQKLQ 58
           +++KQ    +   RD  +++ E E + +    FL +A + + + +A       HE++K+Q
Sbjct: 614 KQIKQTEDSLASERD-RLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQ 672

Query: 59  ESINNLADNVQKFGQQ-QKSLVASMRRFSLLKRESTITKE--IKIQAEYINRSLNDLVKE 115
           +S+    D ++   +Q Q  +   M  F +L  ++   K    K+Q     +   D+V++
Sbjct: 673 QSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQ 732

Query: 116 VKK-------------SEVENGPSSVVTR-----ILKSQHAAMFRHFQQIMFIYNDTI-- 155
           ++K               +E G   V T+      ++++++++ +  Q +    ND +  
Sbjct: 733 MEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSF 792

Query: 156 AAKQEKCKTFILRQ---------------LEVAGKEMSEEDVNDMLHQGKWEVFNESLLT 200
           A+  E+ K  I  +               L+VA KE + +D+   +   K E+ N     
Sbjct: 793 ASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGN----- 847

Query: 201 EINITKAQLSEIEQRHKELVNL----ENQIKDLRDLFIQISLLVEEQGESINNIEMTVNS 256
            + + KAQ   I  + +EL NL    E Q+  ++ +  +    +   G+ + +++    S
Sbjct: 848 -VQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENES 906

Query: 257 TKEYVNNTKE 266
            K +V    +
Sbjct: 907 LKAHVQEVAQ 916



 Score = 30.4 bits (67), Expect = 1.9
 Identities = 53/260 (20%), Positives = 104/260 (40%), Gaps = 28/260 (10%)

Query: 8    LKQRTKEIELSRDSHVSTTETEEQGVFLQQAVIYEREPVAERHLHEIQKLQESINNLADN 67
            L +  K++   +D  + + E   +   L+ A    +E   +    EI+ L+E I N    
Sbjct: 795  LVEELKKVIHEKDGKIKSVEELLEAELLKVA---NKEKTVQDLKQEIKALKEEIGN---- 847

Query: 68   VQKFGQQQKSLVASMRRF-SLLKRESTITKEIKIQAEYINRSLNDLVKEVKKSEVENGP- 125
            VQ    QQ S+ + ++   +LLK +      +K   E   + L +  K ++  + EN   
Sbjct: 848  VQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESL 907

Query: 126  ----SSVVTRILK-SQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFILRQLEVAGKEMSEE 180
                  V    LK +  A+ F   + ++    + +   +   K    R+ +++ K    +
Sbjct: 908  KAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKE---RESDLSSKTQLLQ 964

Query: 181  DVNDMLHQGKWEVFNESLLTEINITKAQ--------LSEIEQRHKELVNLENQIKDLRDL 232
            DV D     K ++     L + N  +A         L  I +R KE+  L N++  L+D 
Sbjct: 965  DVQDENKLFKSQI---EQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDA 1021

Query: 233  FIQISLLVEEQGESINNIEM 252
                     E+ + +  +E+
Sbjct: 1022 VEHQRKKNNERQQQVEAVEL 1041


>gi|33620775 kinectin 1 isoform a [Homo sapiens]
          Length = 1357

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 61/310 (19%), Positives = 133/310 (42%), Gaps = 56/310 (18%)

Query: 6   QELKQRTKEIELSRDSHVSTTETEEQGV----FLQQAVIYEREPVAERHL---HEIQKLQ 58
           +++KQ    +   RD  +++ E E + +    FL +A + + + +A       HE++K+Q
Sbjct: 614 KQIKQTEDSLASERD-RLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQ 672

Query: 59  ESINNLADNVQKFGQQ-QKSLVASMRRFSLLKRESTITKE--IKIQAEYINRSLNDLVKE 115
           +S+    D ++   +Q Q  +   M  F +L  ++   K    K+Q     +   D+V++
Sbjct: 673 QSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQ 732

Query: 116 VKK-------------SEVENGPSSVVTR-----ILKSQHAAMFRHFQQIMFIYNDTI-- 155
           ++K               +E G   V T+      ++++++++ +  Q +    ND +  
Sbjct: 733 MEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSF 792

Query: 156 AAKQEKCKTFILRQ---------------LEVAGKEMSEEDVNDMLHQGKWEVFNESLLT 200
           A+  E+ K  I  +               L+VA KE + +D+   +   K E+ N     
Sbjct: 793 ASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGN----- 847

Query: 201 EINITKAQLSEIEQRHKELVNL----ENQIKDLRDLFIQISLLVEEQGESINNIEMTVNS 256
            + + KAQ   I  + +EL NL    E Q+  ++ +  +    +   G+ + +++    S
Sbjct: 848 -VQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENES 906

Query: 257 TKEYVNNTKE 266
            K +V    +
Sbjct: 907 LKAHVQEVAQ 916



 Score = 31.6 bits (70), Expect = 0.87
 Identities = 58/279 (20%), Positives = 114/279 (40%), Gaps = 32/279 (11%)

Query: 8    LKQRTKEIELSRDSHVSTTETEEQGVFLQQAVIYEREPVAERHLHEIQKLQESINNLADN 67
            L +  K++   +D  + + E   +   L+ A    +E   +    EI+ L+E I N    
Sbjct: 795  LVEELKKVIHEKDGKIKSVEELLEAELLKVA---NKEKTVQDLKQEIKALKEEIGN---- 847

Query: 68   VQKFGQQQKSLVASMRRF-SLLKRESTITKEIKIQAEYINRSLNDLVKEVKKSEVENGP- 125
            VQ    QQ S+ + ++   +LLK +      +K   E   + L +  K ++  + EN   
Sbjct: 848  VQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESL 907

Query: 126  ----SSVVTRILK-SQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFILRQLEVAGKEMSEE 180
                  V    LK +  A+ F   + ++    + +   +   K    R+ +++ K    +
Sbjct: 908  KAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKE---RESDLSSKTQLLQ 964

Query: 181  DVNDMLHQGKWEVFNESLLTEINITKAQ--------LSEIEQRHKELVNLENQIKDLRDL 232
            DV D     K ++     L + N  +A         L  I +R KE+  L N++  L+D 
Sbjct: 965  DVQDENKLFKSQI---EQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDA 1021

Query: 233  F----IQISLLVEEQGESINNIEMTVNSTKEYVNNTKEK 267
                  + + L E+  E++  +  T    ++ VN T ++
Sbjct: 1022 VEHQRKKNNDLREKNWEAMEALASTEKMLQDKVNKTSKE 1060


>gi|114155144 tropomyosin 3 isoform 4 [Homo sapiens]
          Length = 248

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 45/221 (20%), Positives = 92/221 (41%), Gaps = 9/221 (4%)

Query: 53  EIQKLQESINNLADNVQKF-----GQQQKSLVASMRRFSLLKRESTITKEIKIQAEYINR 107
           +IQ LQ+  ++  +  ++      G+++    A     SL +R   + +E+    E +  
Sbjct: 13  KIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVEEELDRAQERLAT 72

Query: 108 SLNDLVKEVKKS-EVENGPSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFI 166
           +L  L +  K + E E G   +  R LK +        Q+I       IA + ++    +
Sbjct: 73  ALQKLEEAEKAADESERGMKVIENRALKDEEKM---ELQEIQLKEAKHIAEEADRKYEEV 129

Query: 167 LRQLEVAGKEMSEEDVNDMLHQGKWEVFNESLLTEINITKAQLSEIEQRHKELVNLENQI 226
            R+L +   ++   +    L + K     E L    N  K+  ++ E+  ++    E +I
Sbjct: 130 ARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEI 189

Query: 227 KDLRDLFIQISLLVEEQGESINNIEMTVNSTKEYVNNTKEK 267
           K L D   +     E    S+  +E T++  ++ +  TKE+
Sbjct: 190 KILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEE 230


>gi|34878777 ring finger protein 20 [Homo sapiens]
          Length = 975

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 57/280 (20%), Positives = 120/280 (42%), Gaps = 37/280 (13%)

Query: 2   KDRLQELKQRTKEIELSRDSHVSTTETEEQGVFLQQAVIYEREPVAERHLHEIQKLQESI 61
           K+R +E KQ+ KE E  RDS     + +      ++A I ++  +    L + Q+ Q+ +
Sbjct: 588 KERERE-KQKLKESEKERDSAKDKEKGKHDDGRKKEAEIIKQLKI---ELKKAQESQKEM 643

Query: 62  NNLADNVQKFGQQQKSLVASMRRFSLLKRESTITKEIKIQAEYINRSLNDLVKEVKKSEV 121
             L D  +   ++Q+  V  M             K+ K + E + + L DL  + KK   
Sbjct: 644 KLLLDMYRSAPKEQRDKVQLM----------AAEKKSKAELEDLRQRLKDLEDKEKKENK 693

Query: 122 ENGPSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFILRQLEVAG---KEMS 178
           +      + +I   +        +QI ++      AKQE  +  +L +++V G   ++M 
Sbjct: 694 KMADEDALRKIRAVE--------EQIEYLQKKLAMAKQE--EEALLSEMDVTGQAFEDMQ 743

Query: 179 EEDVNDMLHQGKWEVFNESLLTEINITKAQLSEIEQRHKELVNLENQIKDLRDLFIQISL 238
           E+++  M    + +  N  L++E  I   Q+ ++ +  KE         +L D  + +  
Sbjct: 744 EQNIRLMQQLREKDDANFKLMSE-RIKSNQIHKLLKEEKE---------ELADQVLTLKT 793

Query: 239 LVEEQGESINNIEMTVNSTKEYVNNTKEKFGLAVKYKKRN 278
            V+ Q + +  +E   +  +  +   +++ GL  +  + N
Sbjct: 794 QVDAQLQVVRKLEEKEHLLQSNIGTGEKELGLRTQALEMN 833


>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
            transmembrane signal), 1 [Homo sapiens]
          Length = 3259

 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 60/298 (20%), Positives = 130/298 (43%), Gaps = 30/298 (10%)

Query: 1    MKDRLQELKQRTKEIELSRDSHV---STTETEEQGVFLQQAVIYEREPVAERHLHEIQKL 57
            ++  ++ LK+   E+E  +   V   +  E+E +  +L++    ++EP  + H  E+Q+L
Sbjct: 1954 LESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQEL 2013

Query: 58   QESINNLADNVQKFGQQQKSLVASMRRFSLLKRE----STITKEIKIQAEYINRSLNDLV 113
                  L +  Q+  Q QK  +    + S L+R       +  E +   E    +L   V
Sbjct: 2014 ------LKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAV 2067

Query: 114  KEVKKSEVENGPSSVVTRILKSQHAAMFR---HFQQIMFIYNDTIAAKQEKCKTFILRQL 170
            +  KK++ E     V+    +S+ A +       ++ +    +++ ++ ++    + R+L
Sbjct: 2068 EHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRL 2127

Query: 171  EVAGKEMSEEDVN-----DMLHQGKWEVFNESLLTEINITKAQLSEIEQRHKELVNLENQ 225
            E A ++  +E  N     D L + K  V  E  + EI +T  +  +  Q+ +E  NL++ 
Sbjct: 2128 EQAEEKHLKEKKNMQEKLDALRREK--VHLEETIGEIQVTLNKKDKEVQQLQE--NLDST 2183

Query: 226  IKDLRDLFIQISLLVEEQGESINNIEMTVNSTKEYVNNTKEKFGLAVKYKKRNPCRVL 283
            +  L      +S L +++   I+  +       + + + +E+  L     K + C VL
Sbjct: 2184 VTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRL-----KEDNCSVL 2236



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 57/276 (20%), Positives = 120/276 (43%), Gaps = 48/276 (17%)

Query: 13   KEIELSRDSHVSTTETEEQGVFLQQAVIYER--EPVAERHLHEIQKLQESINNLADNVQK 70
            KE++ +++S  S  + +++ +        ER  E   E+HL E + +QE +    D +++
Sbjct: 2103 KELQSNKESVKSQMKQKDEDL--------ERRLEQAEEKHLKEKKNMQEKL----DALRR 2150

Query: 71   FGQQQKSLVASMRRFSLLKRESTITKEIKIQAEYINRSLNDLVKEVKK-SEVENGPSSVV 129
                 +  +  ++  +L K++    KE++   E ++ ++  L    K  S +++    V+
Sbjct: 2151 EKVHLEETIGEIQ-VTLNKKD----KEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVI 2205

Query: 130  TRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFI--LRQLEVAGKEMSEEDVNDMLH 187
                K +     R F   +    + I  K++ C      LRQ+ +    M E  +N    
Sbjct: 2206 DEAKKWE-----RKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSI---HMEELKINISRL 2257

Query: 188  QGKWEVFNESLLTEINI-----------TKAQLSEIEQ-RH------KELVNLENQIKDL 229
            +   +++     TE+ +            K  LS++E+ RH       EL  LE+++K L
Sbjct: 2258 EHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSL 2317

Query: 230  RDLFIQISLLVEEQGESINNIEMTVNSTKEYVNNTK 265
            +D    +S  +E+  E   N+E  +   +  + N+K
Sbjct: 2318 KDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSK 2353



 Score = 31.2 bits (69), Expect = 1.1
 Identities = 48/257 (18%), Positives = 102/257 (39%), Gaps = 42/257 (16%)

Query: 1    MKDRLQELKQRTKEIELSRDSHVSTTETEEQGVFLQQAVIYEREPVAERHLHEIQKLQES 60
            +K +LQE + +TK  ++ ++      E  ++ +  Q  +   R   +   +HE +  ++ 
Sbjct: 2917 LKAQLQEYQDKTKAFQIMQE------ELRQENLSWQHELHQLRMEKSSWEIHERRMKEQY 2970

Query: 61   INNLADNVQKFGQQQKSLVASMRRFSLLKRESTI----------------TKEIKIQAEY 104
            +  ++D  Q+    Q +L+  +R  S   +   +                ++ +  + E 
Sbjct: 2971 LMAISDKDQQLSHLQ-NLIRELRSSSSQTQPLKVQYQRQASPETSASPDGSQNLVYETEL 3029

Query: 105  INRSLNDLVKEVKKSEVENGPSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKT 164
            +   LND +KE+ + E+         + L S  + +      +     DT  + +E  + 
Sbjct: 3030 LRTQLNDSLKEIHQKELR-------IQQLNSNFSQLLEEKNTLSIQLCDTSQSLRENQQH 3082

Query: 165  F--ILRQLEVAGKEMSE-------EDVNDMLHQGKWEVFNESLLTEINITKAQLSEIEQR 215
            +  +L    V  K++ E        DV     Q K  V  +S   E+   +   SE +Q 
Sbjct: 3083 YGDLLNHCAVLEKQVQELQAGPLNIDVAPGAPQEKNGVHRKSDPEELREPQQSFSEAQQ- 3141

Query: 216  HKELVNLENQIKDLRDL 232
              +L N   ++ +LR L
Sbjct: 3142 --QLCNTRQEVNELRKL 3156


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.129    0.356 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,157,989
Number of Sequences: 37866
Number of extensions: 353079
Number of successful extensions: 2623
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 65
Number of HSP's successfully gapped in prelim test: 280
Number of HSP's that attempted gapping in prelim test: 2217
Number of HSP's gapped (non-prelim): 671
length of query: 294
length of database: 18,247,518
effective HSP length: 101
effective length of query: 193
effective length of database: 14,423,052
effective search space: 2783649036
effective search space used: 2783649036
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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