Guide to the Human Genome
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Search of human proteins with 4885643

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4885643 tumor protein p53 binding protein, 2 isoform 2 [Homo
sapiens]
         (1005 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|112799849 tumor protein p53 binding protein, 2 isoform 1 [Hom...  2015   0.0  
gi|4885643 tumor protein p53 binding protein, 2 isoform 2 [Homo ...  2015   0.0  
gi|121114287 apoptosis-stimulating protein of p53, 1 [Homo sapiens]   805   0.0  
gi|215820635 protein phosphatase 1, regulatory subunit 13 like [...   281   3e-75
gi|63003907 protein phosphatase 1, regulatory subunit 13 like [H...   281   3e-75
gi|28626517 protein phosphatase 1 regulatory inhibitor subunit 1...    89   2e-17
gi|219842212 protein phosphatase 1, regulatory (inhibitor) subun...    87   8e-17
gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit...    87   8e-17
gi|14249672 protein phosphatase 1, regulatory (inhibitor) subuni...    82   3e-15
gi|14195601 protein phosphatase 1, regulatory (inhibitor) subuni...    82   3e-15
gi|4505319 protein phosphatase 1, regulatory (inhibitor) subunit...    82   3e-15
gi|20270347 ankyrin repeat domain 54 [Homo sapiens]                    75   3e-13
gi|14149716 protein phosphatase 1, regulatory subunit 12C [Homo ...    75   4e-13
gi|32967601 ankyrin 3 isoform 1 [Homo sapiens]                         69   2e-11
gi|188595682 ankyrin 2 isoform 3 [Homo sapiens]                        69   3e-11
gi|52426737 ankyrin 2 isoform 2 [Homo sapiens]                         69   3e-11
gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]                         69   3e-11
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    68   4e-11
gi|4506217 proteasome 26S non-ATPase subunit 10 isoform 1 [Homo ...    67   6e-11
gi|28605137 proteasome 26S non-ATPase subunit 10 isform 2 [Homo ...    67   6e-11
gi|215598574 ankyrin 1 isoform 9 [Homo sapiens]                        67   8e-11
gi|70780359 ankyrin 1 isoform 1 [Homo sapiens]                         67   8e-11
gi|70780357 ankyrin 1 isoform 3 [Homo sapiens]                         67   8e-11
gi|70780355 ankyrin 1 isoform 2 [Homo sapiens]                         67   8e-11
gi|70780353 ankyrin 1 isoform 4 [Homo sapiens]                         67   8e-11
gi|219842214 protein phosphatase 1, regulatory (inhibitor) subun...    66   1e-10
gi|41350198 fetal globin inducing factor [Homo sapiens]                65   4e-10
gi|221139761 zinc finger protein 853 [Homo sapiens]                    64   9e-10
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik...    64   9e-10
gi|56090539 dysferlin-interacting protein 1 [Homo sapiens]             63   2e-09

>gi|112799849 tumor protein p53 binding protein, 2 isoform 1 [Homo
            sapiens]
          Length = 1134

 Score = 2015 bits (5220), Expect = 0.0
 Identities = 1005/1005 (100%), Positives = 1005/1005 (100%)

Query: 1    MDLTLAELQEMASRQQQQIEAQQQLLATKEQRLKFLKQQDQRQQQQVAEQEKLKRLKEIA 60
            MDLTLAELQEMASRQQQQIEAQQQLLATKEQRLKFLKQQDQRQQQQVAEQEKLKRLKEIA
Sbjct: 130  MDLTLAELQEMASRQQQQIEAQQQLLATKEQRLKFLKQQDQRQQQQVAEQEKLKRLKEIA 189

Query: 61   ENQEAKLKKVRALKGHVEQKRLSNGKLVEEIEQMNNLFQQKQRELVLAVSKVEELTRQLE 120
            ENQEAKLKKVRALKGHVEQKRLSNGKLVEEIEQMNNLFQQKQRELVLAVSKVEELTRQLE
Sbjct: 190  ENQEAKLKKVRALKGHVEQKRLSNGKLVEEIEQMNNLFQQKQRELVLAVSKVEELTRQLE 249

Query: 121  MLKNGRIDSHHDNQSAVAELDRLYKELQLRNKLNQEQNAKLQQQRECLNKRNSEVAVMDK 180
            MLKNGRIDSHHDNQSAVAELDRLYKELQLRNKLNQEQNAKLQQQRECLNKRNSEVAVMDK
Sbjct: 250  MLKNGRIDSHHDNQSAVAELDRLYKELQLRNKLNQEQNAKLQQQRECLNKRNSEVAVMDK 309

Query: 181  RVNELRDRLWKKKAALQQKENLPVSSDGNLPQQAASAPSRVAAVGPYIQSSTMPRMPSRP 240
            RVNELRDRLWKKKAALQQKENLPVSSDGNLPQQAASAPSRVAAVGPYIQSSTMPRMPSRP
Sbjct: 310  RVNELRDRLWKKKAALQQKENLPVSSDGNLPQQAASAPSRVAAVGPYIQSSTMPRMPSRP 369

Query: 241  ELLVKPALPDGSLVIQASEGPMKIQTLPNMRSGAASQTKGSKIHPVGPDWSPSNADLFPS 300
            ELLVKPALPDGSLVIQASEGPMKIQTLPNMRSGAASQTKGSKIHPVGPDWSPSNADLFPS
Sbjct: 370  ELLVKPALPDGSLVIQASEGPMKIQTLPNMRSGAASQTKGSKIHPVGPDWSPSNADLFPS 429

Query: 301  QGSASVPQSTGNALDQVDDGEVPLREKEKKVRPFSMFDAVDQSNAPPSFGTLRKNQSSED 360
            QGSASVPQSTGNALDQVDDGEVPLREKEKKVRPFSMFDAVDQSNAPPSFGTLRKNQSSED
Sbjct: 430  QGSASVPQSTGNALDQVDDGEVPLREKEKKVRPFSMFDAVDQSNAPPSFGTLRKNQSSED 489

Query: 361  ILRDAQVANKNVAKVPPPVPTKPKQINLPYFGQTNQPPSDIKPDGSSQQLSTVVPSMGTK 420
            ILRDAQVANKNVAKVPPPVPTKPKQINLPYFGQTNQPPSDIKPDGSSQQLSTVVPSMGTK
Sbjct: 490  ILRDAQVANKNVAKVPPPVPTKPKQINLPYFGQTNQPPSDIKPDGSSQQLSTVVPSMGTK 549

Query: 421  PKPAGQQPRVLLSPSIPSVGQDQTLSPGSKQESPPAAAVRPFTPQPSKDTLLPPFRKPQT 480
            PKPAGQQPRVLLSPSIPSVGQDQTLSPGSKQESPPAAAVRPFTPQPSKDTLLPPFRKPQT
Sbjct: 550  PKPAGQQPRVLLSPSIPSVGQDQTLSPGSKQESPPAAAVRPFTPQPSKDTLLPPFRKPQT 609

Query: 481  VAASSIYSMYTQQQAPGKNFQQAVQSALTKTHTRGPHFSSVYGKPVIAAAQNQQQHPENI 540
            VAASSIYSMYTQQQAPGKNFQQAVQSALTKTHTRGPHFSSVYGKPVIAAAQNQQQHPENI
Sbjct: 610  VAASSIYSMYTQQQAPGKNFQQAVQSALTKTHTRGPHFSSVYGKPVIAAAQNQQQHPENI 669

Query: 541  YSNSQGKPGSPEPETEPVSSVQENHENERIPRPLSPTKLLPFLSNPYRNQSDADLEALRK 600
            YSNSQGKPGSPEPETEPVSSVQENHENERIPRPLSPTKLLPFLSNPYRNQSDADLEALRK
Sbjct: 670  YSNSQGKPGSPEPETEPVSSVQENHENERIPRPLSPTKLLPFLSNPYRNQSDADLEALRK 729

Query: 601  KLSNAPRPLKKRSSITEPEGPNGPNIQKLLYQRTTIAAMETISVPSYPSKSASVTASSES 660
            KLSNAPRPLKKRSSITEPEGPNGPNIQKLLYQRTTIAAMETISVPSYPSKSASVTASSES
Sbjct: 730  KLSNAPRPLKKRSSITEPEGPNGPNIQKLLYQRTTIAAMETISVPSYPSKSASVTASSES 789

Query: 661  PVEIQNPYLHVEPEKEVVSLVPESLSPEDVGNASTENSDMPAPSPGLDYEPEGVPDNSPN 720
            PVEIQNPYLHVEPEKEVVSLVPESLSPEDVGNASTENSDMPAPSPGLDYEPEGVPDNSPN
Sbjct: 790  PVEIQNPYLHVEPEKEVVSLVPESLSPEDVGNASTENSDMPAPSPGLDYEPEGVPDNSPN 849

Query: 721  LQNNPEEPNPEAPHVLDVYLEEYPPYPPPPYPSGEPEGPGEDSVSMRPPEITGQVSLPPG 780
            LQNNPEEPNPEAPHVLDVYLEEYPPYPPPPYPSGEPEGPGEDSVSMRPPEITGQVSLPPG
Sbjct: 850  LQNNPEEPNPEAPHVLDVYLEEYPPYPPPPYPSGEPEGPGEDSVSMRPPEITGQVSLPPG 909

Query: 781  KRTNLRKTGSERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITAL 840
            KRTNLRKTGSERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITAL
Sbjct: 910  KRTNLRKTGSERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITAL 969

Query: 841  HNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMTY 900
            HNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMTY
Sbjct: 970  HNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMTY 1029

Query: 901  SDMQTAADKCEEMEEGYTQCSQFLYGVQEKMGIMNKGVIYALWDYEPQNDDELPMKEGDC 960
            SDMQTAADKCEEMEEGYTQCSQFLYGVQEKMGIMNKGVIYALWDYEPQNDDELPMKEGDC
Sbjct: 1030 SDMQTAADKCEEMEEGYTQCSQFLYGVQEKMGIMNKGVIYALWDYEPQNDDELPMKEGDC 1089

Query: 961  MTIIHREDEDEIEWWWARLNDKEGYVPRNLLGLYPRIKPRQRSLA 1005
            MTIIHREDEDEIEWWWARLNDKEGYVPRNLLGLYPRIKPRQRSLA
Sbjct: 1090 MTIIHREDEDEIEWWWARLNDKEGYVPRNLLGLYPRIKPRQRSLA 1134


>gi|4885643 tumor protein p53 binding protein, 2 isoform 2 [Homo
            sapiens]
          Length = 1005

 Score = 2015 bits (5220), Expect = 0.0
 Identities = 1005/1005 (100%), Positives = 1005/1005 (100%)

Query: 1    MDLTLAELQEMASRQQQQIEAQQQLLATKEQRLKFLKQQDQRQQQQVAEQEKLKRLKEIA 60
            MDLTLAELQEMASRQQQQIEAQQQLLATKEQRLKFLKQQDQRQQQQVAEQEKLKRLKEIA
Sbjct: 1    MDLTLAELQEMASRQQQQIEAQQQLLATKEQRLKFLKQQDQRQQQQVAEQEKLKRLKEIA 60

Query: 61   ENQEAKLKKVRALKGHVEQKRLSNGKLVEEIEQMNNLFQQKQRELVLAVSKVEELTRQLE 120
            ENQEAKLKKVRALKGHVEQKRLSNGKLVEEIEQMNNLFQQKQRELVLAVSKVEELTRQLE
Sbjct: 61   ENQEAKLKKVRALKGHVEQKRLSNGKLVEEIEQMNNLFQQKQRELVLAVSKVEELTRQLE 120

Query: 121  MLKNGRIDSHHDNQSAVAELDRLYKELQLRNKLNQEQNAKLQQQRECLNKRNSEVAVMDK 180
            MLKNGRIDSHHDNQSAVAELDRLYKELQLRNKLNQEQNAKLQQQRECLNKRNSEVAVMDK
Sbjct: 121  MLKNGRIDSHHDNQSAVAELDRLYKELQLRNKLNQEQNAKLQQQRECLNKRNSEVAVMDK 180

Query: 181  RVNELRDRLWKKKAALQQKENLPVSSDGNLPQQAASAPSRVAAVGPYIQSSTMPRMPSRP 240
            RVNELRDRLWKKKAALQQKENLPVSSDGNLPQQAASAPSRVAAVGPYIQSSTMPRMPSRP
Sbjct: 181  RVNELRDRLWKKKAALQQKENLPVSSDGNLPQQAASAPSRVAAVGPYIQSSTMPRMPSRP 240

Query: 241  ELLVKPALPDGSLVIQASEGPMKIQTLPNMRSGAASQTKGSKIHPVGPDWSPSNADLFPS 300
            ELLVKPALPDGSLVIQASEGPMKIQTLPNMRSGAASQTKGSKIHPVGPDWSPSNADLFPS
Sbjct: 241  ELLVKPALPDGSLVIQASEGPMKIQTLPNMRSGAASQTKGSKIHPVGPDWSPSNADLFPS 300

Query: 301  QGSASVPQSTGNALDQVDDGEVPLREKEKKVRPFSMFDAVDQSNAPPSFGTLRKNQSSED 360
            QGSASVPQSTGNALDQVDDGEVPLREKEKKVRPFSMFDAVDQSNAPPSFGTLRKNQSSED
Sbjct: 301  QGSASVPQSTGNALDQVDDGEVPLREKEKKVRPFSMFDAVDQSNAPPSFGTLRKNQSSED 360

Query: 361  ILRDAQVANKNVAKVPPPVPTKPKQINLPYFGQTNQPPSDIKPDGSSQQLSTVVPSMGTK 420
            ILRDAQVANKNVAKVPPPVPTKPKQINLPYFGQTNQPPSDIKPDGSSQQLSTVVPSMGTK
Sbjct: 361  ILRDAQVANKNVAKVPPPVPTKPKQINLPYFGQTNQPPSDIKPDGSSQQLSTVVPSMGTK 420

Query: 421  PKPAGQQPRVLLSPSIPSVGQDQTLSPGSKQESPPAAAVRPFTPQPSKDTLLPPFRKPQT 480
            PKPAGQQPRVLLSPSIPSVGQDQTLSPGSKQESPPAAAVRPFTPQPSKDTLLPPFRKPQT
Sbjct: 421  PKPAGQQPRVLLSPSIPSVGQDQTLSPGSKQESPPAAAVRPFTPQPSKDTLLPPFRKPQT 480

Query: 481  VAASSIYSMYTQQQAPGKNFQQAVQSALTKTHTRGPHFSSVYGKPVIAAAQNQQQHPENI 540
            VAASSIYSMYTQQQAPGKNFQQAVQSALTKTHTRGPHFSSVYGKPVIAAAQNQQQHPENI
Sbjct: 481  VAASSIYSMYTQQQAPGKNFQQAVQSALTKTHTRGPHFSSVYGKPVIAAAQNQQQHPENI 540

Query: 541  YSNSQGKPGSPEPETEPVSSVQENHENERIPRPLSPTKLLPFLSNPYRNQSDADLEALRK 600
            YSNSQGKPGSPEPETEPVSSVQENHENERIPRPLSPTKLLPFLSNPYRNQSDADLEALRK
Sbjct: 541  YSNSQGKPGSPEPETEPVSSVQENHENERIPRPLSPTKLLPFLSNPYRNQSDADLEALRK 600

Query: 601  KLSNAPRPLKKRSSITEPEGPNGPNIQKLLYQRTTIAAMETISVPSYPSKSASVTASSES 660
            KLSNAPRPLKKRSSITEPEGPNGPNIQKLLYQRTTIAAMETISVPSYPSKSASVTASSES
Sbjct: 601  KLSNAPRPLKKRSSITEPEGPNGPNIQKLLYQRTTIAAMETISVPSYPSKSASVTASSES 660

Query: 661  PVEIQNPYLHVEPEKEVVSLVPESLSPEDVGNASTENSDMPAPSPGLDYEPEGVPDNSPN 720
            PVEIQNPYLHVEPEKEVVSLVPESLSPEDVGNASTENSDMPAPSPGLDYEPEGVPDNSPN
Sbjct: 661  PVEIQNPYLHVEPEKEVVSLVPESLSPEDVGNASTENSDMPAPSPGLDYEPEGVPDNSPN 720

Query: 721  LQNNPEEPNPEAPHVLDVYLEEYPPYPPPPYPSGEPEGPGEDSVSMRPPEITGQVSLPPG 780
            LQNNPEEPNPEAPHVLDVYLEEYPPYPPPPYPSGEPEGPGEDSVSMRPPEITGQVSLPPG
Sbjct: 721  LQNNPEEPNPEAPHVLDVYLEEYPPYPPPPYPSGEPEGPGEDSVSMRPPEITGQVSLPPG 780

Query: 781  KRTNLRKTGSERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITAL 840
            KRTNLRKTGSERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITAL
Sbjct: 781  KRTNLRKTGSERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITAL 840

Query: 841  HNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMTY 900
            HNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMTY
Sbjct: 841  HNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMTY 900

Query: 901  SDMQTAADKCEEMEEGYTQCSQFLYGVQEKMGIMNKGVIYALWDYEPQNDDELPMKEGDC 960
            SDMQTAADKCEEMEEGYTQCSQFLYGVQEKMGIMNKGVIYALWDYEPQNDDELPMKEGDC
Sbjct: 901  SDMQTAADKCEEMEEGYTQCSQFLYGVQEKMGIMNKGVIYALWDYEPQNDDELPMKEGDC 960

Query: 961  MTIIHREDEDEIEWWWARLNDKEGYVPRNLLGLYPRIKPRQRSLA 1005
            MTIIHREDEDEIEWWWARLNDKEGYVPRNLLGLYPRIKPRQRSLA
Sbjct: 961  MTIIHREDEDEIEWWWARLNDKEGYVPRNLLGLYPRIKPRQRSLA 1005


>gi|121114287 apoptosis-stimulating protein of p53, 1 [Homo sapiens]
          Length = 1090

 Score =  805 bits (2078), Expect = 0.0
 Identities = 478/1030 (46%), Positives = 611/1030 (59%), Gaps = 88/1030 (8%)

Query: 1    MDLTLAELQEMASRQQQQIEAQQQLLATKEQRLKFLKQQDQRQQQQVAEQEKLKRLKEIA 60
            ++LTL+ELQ+MA+RQQQQIE QQQ+L  KEQRL FLKQQ++RQQQ ++E EKL++LKE  
Sbjct: 124  VELTLSELQDMAARQQQQIENQQQMLVAKEQRLHFLKQQERRQQQSISENEKLQKLKERV 183

Query: 61   ENQEAKLKKVRALKGHVEQKRLSNGKLVEEIEQMNNLFQQKQRELVLAVSKVEELTRQLE 120
            E QE KLKK+RA++G V+  ++ NG L  EIE+ + +FQ+K++E+  A+ +V++L++QLE
Sbjct: 184  EAQENKLKKIRAMRGQVDYSKIMNGNLSAEIERFSAMFQEKKQEVQTAILRVDQLSQQLE 243

Query: 121  MLKNGRIDSHHDNQS-----AVAELDRLYKELQLRNKLNQEQNAKLQQQRECLNKRNSEV 175
             LK G+++            A  EL RLY+ELQ+RN+LNQEQN+KLQQQ+E LNKRN EV
Sbjct: 244  DLKKGKLNGFQSYNGKLTGPAAVELKRLYQELQIRNQLNQEQNSKLQQQKELLNKRNMEV 303

Query: 176  AVMDKRVNELRDRLWKKKAALQQKENLPVSSDGNLPQQAASAPSRVAAVGPYIQSSTMPR 235
            A+MDKR++ELR+RL+ KK  L +          + PQ   S   RVAAVGPYIQ  +   
Sbjct: 304  AMMDKRISELRERLYGKKIQLNRVNGT------SSPQSPLSTSGRVAAVGPYIQVPSAGS 357

Query: 236  MPSRPELLVKPALPDG-SLVIQASEGPMKIQ---TLPNMRSGAASQTKGSKIHPVGPDWS 291
             P    +L  P  P   S+   A+ G  K       P ++  ++S  K   +   G DW 
Sbjct: 358  FP----VLGDPIKPQSLSIASNAAHGRSKSANDGNWPTLKQNSSSSVK--PVQVAGADWK 411

Query: 292  PSNADLFPSQGSASVPQSTGNALDQVDDGEVPLREKEKKVRPFSMFDAVDQSNAPPSFGT 351
              + +    QG+ S      +AL   +   + + +    +              PPS+GT
Sbjct: 412  DPSVEGSVKQGTVSSQPVPFSALGPTEKPGIEIGKVPPPIPGVG-------KQLPPSYGT 464

Query: 352  LRKNQSSEDILRDAQVANKNVAKVPPP---VPTKPKQINLPYFGQTNQPPSDIKPDGSSQ 408
               + +       + +  +    +P P   +P++ +   LP  G T QP       GSSQ
Sbjct: 465  Y-PSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATGSTPQP-------GSSQ 516

Query: 409  QLSTVVPSMGTKPKPAGQQPRVLLSPSIPSVGQDQTLSPGSKQESPPAAAVRPFTPQPSK 468
            Q+               Q+  V  SP+ P  G     +  SK E P   A+RPF      
Sbjct: 517  QIQ--------------QRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGS 562

Query: 469  DTLLPPFRKPQTVAASSIYSMYTQQQAPGKNFQQAVQSALTKTHTRGPHFSSVYGKPVIA 528
                 P + PQTV +SSIYSMY QQ  P KN+Q A  SAL K+        +VYGKPV+ 
Sbjct: 563  RP-QSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKS------VKAVYGKPVLP 615

Query: 529  AAQNQQQ-----HPENIYSNSQGKPGS----PEPETEPVSSVQENHENERIPRPLSPTKL 579
            +           H        Q +P S     EPE +  ++  +    E +PRPLSPTKL
Sbjct: 616  SGSTSPSPLPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRPLSPTKL 675

Query: 580  LPFLSNPYRNQSDADLEALRKKLSNAPRPLKKRSSITEPEGPNGPNIQKLLYQRTTIAAM 639
             P + +P R QSDADLEALR+KL+NAPRPLKKRSSITEPEGP GPNIQKLLYQR    A 
Sbjct: 676  TPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNTLAG 735

Query: 640  ETISVPSYPSKSASVTASSESPVEIQNPYLHVEPEKEVVSLVPESLSPEDVGNASTENSD 699
                 P Y    +     + + V+  N   +   E+   +     L  E   ++   +++
Sbjct: 736  GMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPSSDANDNE 795

Query: 700  MPAPSPGLDYEPEGVPDNSPNLQNNPEEPNPEAPHVLDVYLEEYPPYPPPPYPSGEPEGP 759
            +P+P P    E    P  +       E+ N     V        P     P P  E   P
Sbjct: 796  LPSPEP----EELICPQTTHQTAEPAEDNNNNVATV--------PTTEQIPSPVAEAPSP 843

Query: 760  GEDSVSMRPPEITGQVSLPP----GKRTNLRKTGSERIAHGMRVKFNPLALLLDSSLEGE 815
            GE+ V   PP      S PP     KRTNL+K  SER  HG+RV+FNPLALLLD+SLEGE
Sbjct: 844  GEEQV---PPAPLPPASHPPATSTNKRTNLKKPNSERTGHGLRVRFNPLALLLDASLEGE 900

Query: 816  FDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHC 875
            FDLVQRIIYEV+DPS PNDEGIT LHNAVCAGH  IVKFL+ FGVNVNAADSDGWTPLHC
Sbjct: 901  FDLVQRIIYEVEDPSKPNDEGITPLHNAVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHC 960

Query: 876  AASCNNVQVCKFLVESGAAVFAMTYSDMQTAADKCEEMEEGYTQCSQFLYGVQEKMGIMN 935
            AASCN+V +CK LVESGAA+FA T SD++TAADKCEEMEEGY QCSQFLYGVQEK+G+MN
Sbjct: 961  AASCNSVHLCKQLVESGAAIFASTISDIETAADKCEEMEEGYIQCSQFLYGVQEKLGVMN 1020

Query: 936  KGVIYALWDYEPQNDDELPMKEGDCMTIIHREDEDEIEWWWARLNDKEGYVPRNLLGLYP 995
            KGV YALWDYE QN DEL   EGD +TI+ R+DE E EWWWARL D+EGYVP+NLLGLYP
Sbjct: 1021 KGVAYALWDYEAQNSDELSFHEGDALTILRRKDESETEWWWARLGDREGYVPKNLLGLYP 1080

Query: 996  RIKPRQRSLA 1005
            RIKPRQR+LA
Sbjct: 1081 RIKPRQRTLA 1090


>gi|215820635 protein phosphatase 1, regulatory subunit 13 like [Homo
            sapiens]
          Length = 828

 Score =  281 bits (718), Expect = 3e-75
 Identities = 237/810 (29%), Positives = 346/810 (42%), Gaps = 133/810 (16%)

Query: 285  PVGPDWSPSNADLFPSQGSASVPQ---STGNALDQVDDG-EVPLREKEKK--VRPFSMFD 338
            P GP   P +    P   S+S+P+   S G+      DG + P    E    + P+S   
Sbjct: 56   PPGPQAGPPSRP--PRYSSSSIPEPFGSRGSPRKAATDGADTPFGRSESAPTLHPYSPLS 113

Query: 339  AVDQSNAP--------PSFGTLRKNQSSEDILRDAQVANKNVAKVPPPVPTKPKQINLP- 389
               + ++P         ++G+L +  S      D   ++   A  P P P   +Q   P 
Sbjct: 114  PKGRPSSPRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRAPSPRPGPGPLRQQGPPT 173

Query: 390  ---YFGQTNQPPSDIKPDGSSQQLSTVVPSMGTKPKPAGQQPRVLLSPSIPSVGQDQTLS 446
               + G+   P      +G         P  G  P+P    P         + G    L 
Sbjct: 174  PFDFLGRAGSPRGSPLAEGPQ----AFFPERGPSPRP----PATAYDAPASAFGSS-LLG 224

Query: 447  PGSKQESPPAAAV-------RPFTPQPSKDTLLPPFRKPQTVAASSIYSMYTQQQAPGKN 499
             G    +PP  A        RP       D  +   +KP   A+     ++ +  +P   
Sbjct: 225  SGGSAFAPPLRAQDDLTLRRRPPKAWNESDLDVAYEKKPSQTASYERLDVFARPASPSLQ 284

Query: 500  FQQAVQSALTKTHTRGPHFSSVYGKP---VIAAAQNQQQHPENIYSNSQGKPG------- 549
                 +S+L      G    +    P    ++   + ++     Y  S G  G       
Sbjct: 285  LLPWRESSLDGLGGTGKDNLTSATLPRNYKVSPLASDRRSDAGSYRRSLGSAGPSGTLPR 344

Query: 550  SPEPETE---PVSSVQENHENERIPRPLSPTKLLPFLSNPYRNQ---------SDADLEA 597
            S +P +    P SS Q      + P PLS   ++  L N +            S     A
Sbjct: 345  SWQPVSRIPMPPSSPQPRGAPRQRPIPLS---MIFKLQNAFWEHGASRAMLPGSPLFTRA 401

Query: 598  LRKKLSNAPRPLKKRSSITEPEGPNGPNIQKLLYQRTTIAAMETISVPSYPSKSASVTAS 657
               KL   P+P  +  S  +P+ P  P  Q    Q  T A       P +P ++      
Sbjct: 402  PPPKLQPQPQPQPQPQSQPQPQLPPQPQTQP---QTPTPA-------PQHPQQTWPPV-- 449

Query: 658  SESPVEIQNPYLHVEPEKEVVSLVPESLSPEDVGNASTENSDMPAP-SPGLDYEPEGVPD 716
            +E P +   P   +EPE E+  L+   L   DV          P    P L  E + VP+
Sbjct: 450  NEGPPK---PPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPTRLQPALPPEAQSVPE 506

Query: 717  NSPNLQNNPEEPNP--------EAPHVL--DVYLEEY----------------------- 743
                 +   E P P        +AP V     + ++Y                       
Sbjct: 507  LEEVARVLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGGPEPEL 566

Query: 744  ------------PPYPPPPYPSGEPEGPGEDSVSMRPPEITGQVSLPPGKRTNLRKTGSE 791
                        PP P PP P   P  P + S    PPE    + +    R+ LRK GS 
Sbjct: 567  SPITEGSEARAGPPAPAPPAPI-PPPAPSQSS----PPEQPQSMEM----RSVLRKAGSP 617

Query: 792  RIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEI 851
            R A   R + NPL LLLD++L GE ++VQ+ + E++DPS PN+EGITALHNA+C  +  I
Sbjct: 618  RKAR--RARLNPLVLLLDAALTGELEVVQQAVKEMNDPSQPNEEGITALHNAICGANYSI 675

Query: 852  VKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMTYSDMQTAADKCE 911
            V FL+  G NVN+ DS GWTPLHCAASCN+  +C  LV+ GAA+FA T SD  TA +KC+
Sbjct: 676  VDFLITAGANVNSPDSHGWTPLHCAASCNDTVICMALVQHGAAIFATTLSDGATAFEKCD 735

Query: 912  EMEEGYTQCSQFLYGVQEKMGIMNKGVIYALWDYEPQNDDELPMKEGDCMTIIHREDEDE 971
               EGY  C+ +L  V++ MG+MN G +YALWDY  +  DEL  +EG+ +T++ R+  +E
Sbjct: 736  PYREGYADCATYLADVEQSMGLMNSGAVYALWDYSAEFGDELSFREGESVTVLRRDGPEE 795

Query: 972  IEWWWARLNDKEGYVPRNLLGLYPRIKPRQ 1001
             +WWWA L+ +EGYVPRN  GL+PR+KP++
Sbjct: 796  TDWWWAALHGQEGYVPRNYFGLFPRVKPQR 825


>gi|63003907 protein phosphatase 1, regulatory subunit 13 like [Homo
            sapiens]
          Length = 828

 Score =  281 bits (718), Expect = 3e-75
 Identities = 237/810 (29%), Positives = 346/810 (42%), Gaps = 133/810 (16%)

Query: 285  PVGPDWSPSNADLFPSQGSASVPQ---STGNALDQVDDG-EVPLREKEKK--VRPFSMFD 338
            P GP   P +    P   S+S+P+   S G+      DG + P    E    + P+S   
Sbjct: 56   PPGPQAGPPSRP--PRYSSSSIPEPFGSRGSPRKAATDGADTPFGRSESAPTLHPYSPLS 113

Query: 339  AVDQSNAP--------PSFGTLRKNQSSEDILRDAQVANKNVAKVPPPVPTKPKQINLP- 389
               + ++P         ++G+L +  S      D   ++   A  P P P   +Q   P 
Sbjct: 114  PKGRPSSPRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRAPSPRPGPGPLRQQGPPT 173

Query: 390  ---YFGQTNQPPSDIKPDGSSQQLSTVVPSMGTKPKPAGQQPRVLLSPSIPSVGQDQTLS 446
               + G+   P      +G         P  G  P+P    P         + G    L 
Sbjct: 174  PFDFLGRAGSPRGSPLAEGPQ----AFFPERGPSPRP----PATAYDAPASAFGSS-LLG 224

Query: 447  PGSKQESPPAAAV-------RPFTPQPSKDTLLPPFRKPQTVAASSIYSMYTQQQAPGKN 499
             G    +PP  A        RP       D  +   +KP   A+     ++ +  +P   
Sbjct: 225  SGGSAFAPPLRAQDDLTLRRRPPKAWNESDLDVAYEKKPSQTASYERLDVFARPASPSLQ 284

Query: 500  FQQAVQSALTKTHTRGPHFSSVYGKP---VIAAAQNQQQHPENIYSNSQGKPG------- 549
                 +S+L      G    +    P    ++   + ++     Y  S G  G       
Sbjct: 285  LLPWRESSLDGLGGTGKDNLTSATLPRNYKVSPLASDRRSDAGSYRRSLGSAGPSGTLPR 344

Query: 550  SPEPETE---PVSSVQENHENERIPRPLSPTKLLPFLSNPYRNQ---------SDADLEA 597
            S +P +    P SS Q      + P PLS   ++  L N +            S     A
Sbjct: 345  SWQPVSRIPMPPSSPQPRGAPRQRPIPLS---MIFKLQNAFWEHGASRAMLPGSPLFTRA 401

Query: 598  LRKKLSNAPRPLKKRSSITEPEGPNGPNIQKLLYQRTTIAAMETISVPSYPSKSASVTAS 657
               KL   P+P  +  S  +P+ P  P  Q    Q  T A       P +P ++      
Sbjct: 402  PPPKLQPQPQPQPQPQSQPQPQLPPQPQTQP---QTPTPA-------PQHPQQTWPPV-- 449

Query: 658  SESPVEIQNPYLHVEPEKEVVSLVPESLSPEDVGNASTENSDMPAP-SPGLDYEPEGVPD 716
            +E P +   P   +EPE E+  L+   L   DV          P    P L  E + VP+
Sbjct: 450  NEGPPK---PPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPTRLQPALPPEAQSVPE 506

Query: 717  NSPNLQNNPEEPNP--------EAPHVL--DVYLEEY----------------------- 743
                 +   E P P        +AP V     + ++Y                       
Sbjct: 507  LEEVARVLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGGPEPEL 566

Query: 744  ------------PPYPPPPYPSGEPEGPGEDSVSMRPPEITGQVSLPPGKRTNLRKTGSE 791
                        PP P PP P   P  P + S    PPE    + +    R+ LRK GS 
Sbjct: 567  SPITEGSEARAGPPAPAPPAPI-PPPAPSQSS----PPEQPQSMEM----RSVLRKAGSP 617

Query: 792  RIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEI 851
            R A   R + NPL LLLD++L GE ++VQ+ + E++DPS PN+EGITALHNA+C  +  I
Sbjct: 618  RKAR--RARLNPLVLLLDAALTGELEVVQQAVKEMNDPSQPNEEGITALHNAICGANYSI 675

Query: 852  VKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMTYSDMQTAADKCE 911
            V FL+  G NVN+ DS GWTPLHCAASCN+  +C  LV+ GAA+FA T SD  TA +KC+
Sbjct: 676  VDFLITAGANVNSPDSHGWTPLHCAASCNDTVICMALVQHGAAIFATTLSDGATAFEKCD 735

Query: 912  EMEEGYTQCSQFLYGVQEKMGIMNKGVIYALWDYEPQNDDELPMKEGDCMTIIHREDEDE 971
               EGY  C+ +L  V++ MG+MN G +YALWDY  +  DEL  +EG+ +T++ R+  +E
Sbjct: 736  PYREGYADCATYLADVEQSMGLMNSGAVYALWDYSAEFGDELSFREGESVTVLRRDGPEE 795

Query: 972  IEWWWARLNDKEGYVPRNLLGLYPRIKPRQ 1001
             +WWWA L+ +EGYVPRN  GL+PR+KP++
Sbjct: 796  TDWWWAALHGQEGYVPRNYFGLFPRVKPQR 825


>gi|28626517 protein phosphatase 1 regulatory inhibitor subunit 16B
           [Homo sapiens]
          Length = 567

 Score = 89.0 bits (219), Expect = 2e-17
 Identities = 50/132 (37%), Positives = 71/132 (53%), Gaps = 5/132 (3%)

Query: 781 KRTNLRKTGSERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITAL 840
           K    R TG  R     +V F     LL++SL  + + V+  +     P L N++G+TAL
Sbjct: 50  KHERKRSTGGRR----KKVSFEASVALLEASLRNDAEEVRYFLKNKVSPDLCNEDGLTAL 105

Query: 841 HNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMTY 900
           H        EIVK L+  G NVNA D++ WTPLH AA+C ++ + K LV+ GA + A+  
Sbjct: 106 HQCCIDNFEEIVKLLLSHGANVNAKDNELWTPLHAAATCGHINLVKILVQYGADLLAVN- 164

Query: 901 SDMQTAADKCEE 912
           SD     D CE+
Sbjct: 165 SDGNMPYDLCED 176



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 32/80 (40%), Positives = 43/80 (53%), Gaps = 1/80 (1%)

Query: 835 EGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAA 894
           +G T LH A   G+    + L+  GV V+  D DGW PLH AA    +Q+ + LV  GA+
Sbjct: 228 QGATLLHIAGANGYLRAAELLLDHGVRVDVKDWDGWEPLHAAAFWGQMQMAELLVSHGAS 287

Query: 895 VFAMTYSDMQTAADKCEEME 914
           + A T  D +   D CEE E
Sbjct: 288 LSARTSMD-EMPIDLCEEEE 306


>gi|219842212 protein phosphatase 1, regulatory (inhibitor) subunit
           12A isoform a [Homo sapiens]
          Length = 1030

 Score = 87.0 bits (214), Expect = 8e-17
 Identities = 48/120 (40%), Positives = 73/120 (60%), Gaps = 3/120 (2%)

Query: 798 RVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQ 857
           +VKF+  A+ L +   G+ D V ++++   D +  N +G+TALH A    + ++VKFLV+
Sbjct: 35  KVKFDDGAVFLAACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVE 94

Query: 858 FGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMTYSDMQTAADKCEE--MEE 915
            G N+N  D++GW PLH AASC  + + +FL+  GA V A+  S+  T  D  EE  MEE
Sbjct: 95  NGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVN-SEGDTPLDIAEEEAMEE 153



 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 36/84 (42%), Positives = 47/84 (55%), Gaps = 1/84 (1%)

Query: 836 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAV 895
           G TALH A   G+TE++K L+Q G +VN  D DGWTPLH AA     + C+ LV++    
Sbjct: 199 GGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDN-LCD 257

Query: 896 FAMTYSDMQTAADKCEEMEEGYTQ 919
             M     QTA D  +E   GY +
Sbjct: 258 MEMVNKVGQTAFDVADEDILGYLE 281


>gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit
           12A isoform a [Homo sapiens]
          Length = 1030

 Score = 87.0 bits (214), Expect = 8e-17
 Identities = 48/120 (40%), Positives = 73/120 (60%), Gaps = 3/120 (2%)

Query: 798 RVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQ 857
           +VKF+  A+ L +   G+ D V ++++   D +  N +G+TALH A    + ++VKFLV+
Sbjct: 35  KVKFDDGAVFLAACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVE 94

Query: 858 FGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMTYSDMQTAADKCEE--MEE 915
            G N+N  D++GW PLH AASC  + + +FL+  GA V A+  S+  T  D  EE  MEE
Sbjct: 95  NGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVN-SEGDTPLDIAEEEAMEE 153



 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 36/84 (42%), Positives = 47/84 (55%), Gaps = 1/84 (1%)

Query: 836 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAV 895
           G TALH A   G+TE++K L+Q G +VN  D DGWTPLH AA     + C+ LV++    
Sbjct: 199 GGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDN-LCD 257

Query: 896 FAMTYSDMQTAADKCEEMEEGYTQ 919
             M     QTA D  +E   GY +
Sbjct: 258 MEMVNKVGQTAFDVADEDILGYLE 281


>gi|14249672 protein phosphatase 1, regulatory (inhibitor) subunit
           16A [Homo sapiens]
          Length = 528

 Score = 82.0 bits (201), Expect = 3e-15
 Identities = 43/135 (31%), Positives = 77/135 (57%), Gaps = 3/135 (2%)

Query: 780 GKRTNLRKTGSERIAHGM--RVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGI 837
           GK+    +   E  + G+  +V F P  +LL+++   + + V++ +     P L N++G+
Sbjct: 46  GKKGPGERPRKEAASQGLLKQVLFPPSVVLLEAAARNDLEEVRQFLGSGVSPDLANEDGL 105

Query: 838 TALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFA 897
           TALH        E+V+ L++ G N+NA DS+ WTPLH AA+C ++ + + L+ SGA + A
Sbjct: 106 TALHQCCIDDFREMVQQLLEAGANINACDSECWTPLHAAATCGHLHLVELLIASGANLLA 165

Query: 898 MTYSDMQTAADKCEE 912
           +  +D     D C++
Sbjct: 166 VN-TDGNMPYDLCDD 179



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 1/87 (1%)

Query: 828 DPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKF 887
           D   P D G T LH A   G +E    L++   +++A D DGW PLH AA    V + + 
Sbjct: 224 DLHAPLDHGATLLHVAAANGFSEAAALLLEHRASLSAKDQDGWEPLHAAAYWGQVPLVEL 283

Query: 888 LVESGAAVFAMTYSDMQTAADKCEEME 914
           LV  GA + A +  D +T  D C + E
Sbjct: 284 LVAHGADLNAKSLMD-ETPLDVCGDEE 309


>gi|14195601 protein phosphatase 1, regulatory (inhibitor) subunit
           12B isoform b [Homo sapiens]
          Length = 998

 Score = 81.6 bits (200), Expect = 3e-15
 Identities = 42/115 (36%), Positives = 69/115 (60%), Gaps = 1/115 (0%)

Query: 798 RVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQ 857
           RV+F   A+ L +   G+ D V++++    D +  N +G+TALH A    + ++VKFLV+
Sbjct: 53  RVRFEDGAVFLAACSSGDTDEVRKLLARGADINTVNVDGLTALHQACIDENLDMVKFLVE 112

Query: 858 FGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMTYSDMQTAADKCEE 912
              NVN  D++GWTPLH AASC  + + ++ +  GA+V  +  S+ +  +D  EE
Sbjct: 113 NRANVNQQDNEGWTPLHAAASCGYLNIAEYFINHGASV-GIVNSEGEVPSDLAEE 166



 Score = 58.2 bits (139), Expect = 4e-08
 Identities = 25/56 (44%), Positives = 34/56 (60%)

Query: 836 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVES 891
           G TALH A   G++E+++ L+Q G  +N  D DGWTPLH AA     + C  L E+
Sbjct: 217 GATALHVAAAKGYSEVLRLLIQAGYELNVQDYDGWTPLHAAAHWGVKEACSILAEA 272



 Score = 31.6 bits (70), Expect = 3.9
 Identities = 28/109 (25%), Positives = 47/109 (43%), Gaps = 7/109 (6%)

Query: 625 NIQKLLYQRTTIAAMETISVPSYPSKSASVTASSESPVEIQNPYLHVEPEKEVVSLVPES 684
           N +K+LY+  T  + E        +K +S ++S E   E ++     E EKE        
Sbjct: 334 NKEKMLYEEETPKSQEM----EEENKESSSSSSEEE--EGEDEASESETEKEADKKPEAF 387

Query: 685 LSPEDVGNASTENSDMPAPSPGLDYEPEGVPDNSPNLQNNPEEPNPEAP 733
           ++  +  + S+    +PAP+    +        S  L N PEEP  E+P
Sbjct: 388 VNHSNSESKSSITEQIPAPAQNT-FSASSARRFSSGLFNKPEEPKDESP 435


>gi|4505319 protein phosphatase 1, regulatory (inhibitor) subunit
           12B isoform a [Homo sapiens]
          Length = 982

 Score = 81.6 bits (200), Expect = 3e-15
 Identities = 42/115 (36%), Positives = 69/115 (60%), Gaps = 1/115 (0%)

Query: 798 RVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQ 857
           RV+F   A+ L +   G+ D V++++    D +  N +G+TALH A    + ++VKFLV+
Sbjct: 53  RVRFEDGAVFLAACSSGDTDEVRKLLARGADINTVNVDGLTALHQACIDENLDMVKFLVE 112

Query: 858 FGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMTYSDMQTAADKCEE 912
              NVN  D++GWTPLH AASC  + + ++ +  GA+V  +  S+ +  +D  EE
Sbjct: 113 NRANVNQQDNEGWTPLHAAASCGYLNIAEYFINHGASV-GIVNSEGEVPSDLAEE 166



 Score = 58.2 bits (139), Expect = 4e-08
 Identities = 25/56 (44%), Positives = 34/56 (60%)

Query: 836 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVES 891
           G TALH A   G++E+++ L+Q G  +N  D DGWTPLH AA     + C  L E+
Sbjct: 217 GATALHVAAAKGYSEVLRLLIQAGYELNVQDYDGWTPLHAAAHWGVKEACSILAEA 272



 Score = 31.6 bits (70), Expect = 3.9
 Identities = 28/109 (25%), Positives = 47/109 (43%), Gaps = 7/109 (6%)

Query: 625 NIQKLLYQRTTIAAMETISVPSYPSKSASVTASSESPVEIQNPYLHVEPEKEVVSLVPES 684
           N +K+LY+  T  + E        +K +S ++S E   E ++     E EKE        
Sbjct: 334 NKEKMLYEEETPKSQEM----EEENKESSSSSSEEE--EGEDEASESETEKEADKKPEAF 387

Query: 685 LSPEDVGNASTENSDMPAPSPGLDYEPEGVPDNSPNLQNNPEEPNPEAP 733
           ++  +  + S+    +PAP+    +        S  L N PEEP  E+P
Sbjct: 388 VNHSNSESKSSITEQIPAPAQNT-FSASSARRFSSGLFNKPEEPKDESP 435


>gi|20270347 ankyrin repeat domain 54 [Homo sapiens]
          Length = 300

 Score = 75.1 bits (183), Expect = 3e-13
 Identities = 49/145 (33%), Positives = 76/145 (52%), Gaps = 10/145 (6%)

Query: 804 LALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVN 863
           L  L DS+   + + VQ+++ +  DP   +D+G TALH A C G+ +IV+ L+  G + N
Sbjct: 111 LKRLRDSANANDVETVQQLLEDGADPCAADDKGRTALHFASCNGNDQIVQLLLDHGADPN 170

Query: 864 AADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMT---YSDMQTAADKCEEMEEGYTQC 920
             D  G TPLH AA  N+V V   L+  GA V A+     + +  A  K   ++EG+ QC
Sbjct: 171 QRDGLGNTPLHLAACTNHVPVITTLLRGGARVDALDRAGRTPLHLAKSKLNILQEGHAQC 230

Query: 921 SQFLYGVQEKMGIMNKGVIYALWDY 945
                   E + +  K +I+ L +Y
Sbjct: 231 -------LEAVRLEVKQIIHMLREY 248


>gi|14149716 protein phosphatase 1, regulatory subunit 12C [Homo
           sapiens]
          Length = 782

 Score = 74.7 bits (182), Expect = 4e-13
 Identities = 56/175 (32%), Positives = 81/175 (46%), Gaps = 22/175 (12%)

Query: 754 GEPEGPGEDSVSMRPPEITGQVSLPPGKRTNLRKTGSERIAHGMRVKFNPLALLLDSSLE 813
           G   GPG  + + R  E   +     G R        ER A    V+F   A  L +   
Sbjct: 6   GPAAGPGAAAAAAR--ERRREQLRQWGARAGAEPGPGERRAR--TVRFERAAEFLAACAG 61

Query: 814 GEFDLVQRIIYEVD-------DPSLP----------NDEGITALHNAVCAGHTEIVKFLV 856
           G+ D  + ++   D       DP+ P          N +GI+ALH A    + E+V+FLV
Sbjct: 62  GDLDEARLMLRAADPGPGAELDPAAPPPARAVLDSTNADGISALHQACIDENLEVVRFLV 121

Query: 857 QFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMTYSDMQTAADKCE 911
           + G  VN AD++GWTPLH AASC  + + ++L+  GA + A+  SD     D  E
Sbjct: 122 EQGATVNQADNEGWTPLHVAASCGYLDIARYLLSHGANIAAVN-SDGDLPLDLAE 175



 Score = 57.8 bits (138), Expect = 5e-08
 Identities = 28/77 (36%), Positives = 42/77 (54%), Gaps = 1/77 (1%)

Query: 836 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAV 895
           G +ALH A   G+ E+++ L+Q G +    D DGWTPLH AA       C+ L E G  +
Sbjct: 227 GASALHVAAAKGYIEVMRLLLQAGYDPELRDGDGWTPLHAAAHWGVEDACRLLAEHGGGM 286

Query: 896 FAMTYSDMQTAADKCEE 912
            ++T++  Q   D  +E
Sbjct: 287 DSLTHAG-QRPCDLADE 302



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 27/101 (26%), Positives = 49/101 (48%), Gaps = 11/101 (10%)

Query: 778 PPGKRTNLRKTGSERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGI 837
           PP  R  L  T ++ I+            L  + ++   ++V+ ++ +    +  ++EG 
Sbjct: 87  PPPARAVLDSTNADGIS-----------ALHQACIDENLEVVRFLVEQGATVNQADNEGW 135

Query: 838 TALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAAS 878
           T LH A   G+ +I ++L+  G N+ A +SDG  PL  A S
Sbjct: 136 TPLHVAASCGYLDIARYLLSHGANIAAVNSDGDLPLDLAES 176


>gi|32967601 ankyrin 3 isoform 1 [Homo sapiens]
          Length = 4377

 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 38/93 (40%), Positives = 56/93 (60%)

Query: 802 NPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVN 861
           N L  L  +S EG  ++V  ++    +      +G TALH A  AG  E+VK LV  G N
Sbjct: 73  NGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGAN 132

Query: 862 VNAADSDGWTPLHCAASCNNVQVCKFLVESGAA 894
           VNA   +G+TPL+ AA  N+++V KFL+++GA+
Sbjct: 133 VNAQSQNGFTPLYMAAQENHLEVVKFLLDNGAS 165



 Score = 60.5 bits (145), Expect = 8e-09
 Identities = 38/126 (30%), Positives = 61/126 (48%), Gaps = 9/126 (7%)

Query: 814 GEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPL 873
           G  ++V ++++    P+  N  G TALH A  +G  E+V++LVQ G  V A   D  TPL
Sbjct: 444 GHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPL 503

Query: 874 HCAASCNNVQVCKFLVESGAAVFAMT---YSDMQTAADKCEEMEEGYTQCSQFLYGVQEK 930
           H +A      + + L++ GA+  A T   Y+ +  +A       EG+   + FL      
Sbjct: 504 HISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSA------REGHEDVAAFLLDHGAS 557

Query: 931 MGIMNK 936
           + I  K
Sbjct: 558 LSITTK 563



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 24/81 (29%), Positives = 44/81 (54%)

Query: 814 GEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPL 873
           G+ D+VQ+++ +   P+     G T LH +   GH ++  FL+  G +++     G+TPL
Sbjct: 510 GKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPL 569

Query: 874 HCAASCNNVQVCKFLVESGAA 894
           H AA    ++V   L++  A+
Sbjct: 570 HVAAKYGKLEVANLLLQKSAS 590



 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 40/121 (33%), Positives = 57/121 (47%), Gaps = 5/121 (4%)

Query: 779 PGKRTNLRKTGSERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGIT 838
           P K+   RK   +R     + K +  A  L ++  G  +     I    D ++ N  G+ 
Sbjct: 22  PEKKRKHRKRSRDR-----KKKSDANASYLRAARAGHLEKALDYIKNGVDINICNQNGLN 76

Query: 839 ALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAM 898
           ALH A   GH E+V  L+Q   NV+AA   G T LH A+     +V K LV +GA V A 
Sbjct: 77  ALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQ 136

Query: 899 T 899
           +
Sbjct: 137 S 137



 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 31/100 (31%), Positives = 50/100 (50%), Gaps = 3/100 (3%)

Query: 813 EGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTP 872
           EG  D+V  ++    + +L N  G+T LH A       + + LV  G +V+A    G+TP
Sbjct: 674 EGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTP 733

Query: 873 LHCAASCNNVQVCKFLVESGAAVFAMT---YSDMQTAADK 909
           LH      N+++  FL++  A V A T   Y+ +  AA +
Sbjct: 734 LHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQ 773



 Score = 53.9 bits (128), Expect = 7e-07
 Identities = 29/87 (33%), Positives = 45/87 (51%)

Query: 813 EGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTP 872
           + + D+   ++    D +    +GI ++H A   GH ++V  L+    NVN ++  G TP
Sbjct: 641 KNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTP 700

Query: 873 LHCAASCNNVQVCKFLVESGAAVFAMT 899
           LH AA  + V V + LV  GA V A T
Sbjct: 701 LHLAAQEDRVNVAEVLVNQGAHVDAQT 727



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 29/78 (37%), Positives = 47/78 (60%), Gaps = 3/78 (3%)

Query: 826 VDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVC 885
           VDD +   ++ +TALH A   GH ++ K L+    N NA   +G+TPLH A   N ++V 
Sbjct: 360 VDDVT---NDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVM 416

Query: 886 KFLVESGAAVFAMTYSDM 903
           + L++ GA++ A+T S +
Sbjct: 417 ELLLKHGASIQAVTESGL 434



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 33/123 (26%), Positives = 56/123 (45%), Gaps = 3/123 (2%)

Query: 814 GEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPL 873
           G+ ++   ++ +   P      G+T LH A    + ++   L+  G + +AA  +G+TPL
Sbjct: 576 GKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPL 635

Query: 874 HCAASCNNVQVCKFLVESGAAVFAMTYSDMQTAADKCEEMEEGYTQCSQFLYGVQEKMGI 933
           H AA  N + +   L+E GA   A+T    Q  A      +EG+      L G    + +
Sbjct: 636 HIAAKKNQMDIATTLLEYGADANAVT---RQGIASVHLAAQEGHVDMVSLLLGRNANVNL 692

Query: 934 MNK 936
            NK
Sbjct: 693 SNK 695



 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 36/112 (32%), Positives = 54/112 (48%), Gaps = 6/112 (5%)

Query: 801 FNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGV 860
           + PL L   S+ EG  D+   ++      S+   +G T LH A   G  E+   L+Q   
Sbjct: 533 YTPLHL---SAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSA 589

Query: 861 NVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMT---YSDMQTAADK 909
           + +AA   G TPLH AA  +N +V   L++ GA+  A     Y+ +  AA K
Sbjct: 590 SPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKK 641



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 24/63 (38%), Positives = 35/63 (55%)

Query: 837 ITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVF 896
           IT LH A   G+  +VK L+  G  ++A   DG TPLHC A   + QV + L++  A + 
Sbjct: 269 ITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPIL 328

Query: 897 AMT 899
           + T
Sbjct: 329 SKT 331



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 25/69 (36%), Positives = 35/69 (50%)

Query: 834 DEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 893
           + G+T +H A   GH  IV  L+  G + N  +  G T LH AA     +V ++LV+ GA
Sbjct: 431 ESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGA 490

Query: 894 AVFAMTYSD 902
            V A    D
Sbjct: 491 QVEAKAKDD 499



 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 26/82 (31%), Positives = 45/82 (54%)

Query: 810 SSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDG 869
           +SL G+ ++V+ ++    + +  +  G T L+ A    H E+VKFL+  G + + A  DG
Sbjct: 114 ASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDG 173

Query: 870 WTPLHCAASCNNVQVCKFLVES 891
           +TPL  A    + QV   L+E+
Sbjct: 174 FTPLAVALQQGHDQVVSLLLEN 195



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 23/64 (35%), Positives = 35/64 (54%)

Query: 836 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAV 895
           G T LH     G+ +IV FL+Q    VNA   +G+TPLH AA   +  +   L+++ A+ 
Sbjct: 730 GYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASP 789

Query: 896 FAMT 899
             +T
Sbjct: 790 NELT 793



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 20/81 (24%), Positives = 41/81 (50%)

Query: 814 GEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPL 873
           G + + + ++ +  +P+     G T LH A      ++++ L++ G ++ A    G TP+
Sbjct: 378 GHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPI 437

Query: 874 HCAASCNNVQVCKFLVESGAA 894
           H AA   +V +   L+  GA+
Sbjct: 438 HVAAFMGHVNIVSQLMHHGAS 458



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 30/95 (31%), Positives = 40/95 (42%), Gaps = 7/95 (7%)

Query: 801 FNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGV 860
           F PLA+ L        D V  ++ E D         + ALH A     T+    L+Q   
Sbjct: 174 FTPLAVALQQG----HDQVVSLLLENDTKGKVR---LPALHIAARKDDTKAAALLLQNDN 226

Query: 861 NVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAV 895
           N +     G+TPLH AA   N+ V   L+   AAV
Sbjct: 227 NADVESKSGFTPLHIAAHYGNINVATLLLNRAAAV 261



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 21/58 (36%), Positives = 31/58 (53%)

Query: 836 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 893
           G++ LH A    H   V+ L+Q  V V+   +D  T LH AA C + +V K L++  A
Sbjct: 334 GLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKA 391



 Score = 37.0 bits (84), Expect = 0.093
 Identities = 24/105 (22%), Positives = 50/105 (47%), Gaps = 1/105 (0%)

Query: 802 NPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVN 861
           N +  L  +S  G  ++V+ ++           +G+T LH    +GH ++V+ L+     
Sbjct: 267 NDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAP 326

Query: 862 VNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMTYSDMQTA 906
           + +   +G +PLH A   +++   + L++    V  +T +D  TA
Sbjct: 327 ILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVT-NDYLTA 370



 Score = 36.6 bits (83), Expect = 0.12
 Identities = 20/73 (27%), Positives = 34/73 (46%)

Query: 827 DDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCK 886
           ++  + +  G T LH A   G+  +   L+     V+    +  TPLH A+   N  + K
Sbjct: 226 NNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVK 285

Query: 887 FLVESGAAVFAMT 899
            L++ GA + A T
Sbjct: 286 LLLDRGAKIDAKT 298



 Score = 31.2 bits (69), Expect = 5.1
 Identities = 19/71 (26%), Positives = 28/71 (39%)

Query: 814 GEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPL 873
           G   +V  ++      +     G T LH A   GHT I+  L+Q   + N    +G T L
Sbjct: 741 GNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTAL 800

Query: 874 HCAASCNNVQV 884
             A     + V
Sbjct: 801 GIARRLGYISV 811


>gi|188595682 ankyrin 2 isoform 3 [Homo sapiens]
          Length = 1863

 Score = 68.6 bits (166), Expect = 3e-11
 Identities = 38/92 (41%), Positives = 54/92 (58%)

Query: 802 NPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVN 861
           N L  L  ++ EG   LVQ ++           +G TALH A  AG  E+VK LV+ G N
Sbjct: 42  NGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGAN 101

Query: 862 VNAADSDGWTPLHCAASCNNVQVCKFLVESGA 893
           +NA   +G+TPL+ AA  N++ V K+L+E+GA
Sbjct: 102 INAQSQNGFTPLYMAAQENHIDVVKYLLENGA 133



 Score = 57.0 bits (136), Expect = 9e-08
 Identities = 30/64 (46%), Positives = 39/64 (60%)

Query: 836 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAV 895
           GIT LH A   G+T +VK L+  G  ++A   DG TPLHCAA   + QV + L+E GA +
Sbjct: 245 GITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPL 304

Query: 896 FAMT 899
            A T
Sbjct: 305 LART 308



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 31/78 (39%), Positives = 46/78 (58%), Gaps = 3/78 (3%)

Query: 826 VDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVC 885
           VDD +L   + +TALH A   GH  + K L+    N NA   +G+TPLH A   N ++V 
Sbjct: 337 VDDVTL---DYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVM 393

Query: 886 KFLVESGAAVFAMTYSDM 903
           + LV+ GA++ A+T S +
Sbjct: 394 ELLVKYGASIQAITESGL 411



 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 38/122 (31%), Positives = 58/122 (47%), Gaps = 3/122 (2%)

Query: 791 ERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTE 850
           + +AH      N    L  S+ EG+ D+   ++      SL   +G T LH A   G  +
Sbjct: 497 QHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLD 556

Query: 851 IVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMT---YSDMQTAA 907
           + K L+Q     ++A  +G TPLH AA  +N +V   L+E GA+  A     Y+ +  AA
Sbjct: 557 VAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAA 616

Query: 908 DK 909
            K
Sbjct: 617 KK 618



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 25/82 (30%), Positives = 46/82 (56%)

Query: 810 SSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDG 869
           +SL G+ ++V+ ++ E  + +  +  G T L+ A    H ++VK+L++ G N + A  DG
Sbjct: 83  ASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDG 142

Query: 870 WTPLHCAASCNNVQVCKFLVES 891
           +TPL  A    + Q    L+E+
Sbjct: 143 FTPLAVALQQGHNQAVAILLEN 164



 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 26/57 (45%), Positives = 36/57 (63%)

Query: 838 TALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAA 894
           T LH A   G TEIV+ L+Q   + +AA ++G+TPLH +A    V V   L+E+GAA
Sbjct: 478 TPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAA 534



 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 24/81 (29%), Positives = 41/81 (50%)

Query: 814 GEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPL 873
           G+ ++VQ ++  +  P      G T LH +   G  ++   L++ G   + A   G+TPL
Sbjct: 487 GKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPL 546

Query: 874 HCAASCNNVQVCKFLVESGAA 894
           H AA   ++ V K L++  AA
Sbjct: 547 HVAAKYGSLDVAKLLLQRRAA 567



 Score = 47.4 bits (111), Expect = 7e-05
 Identities = 28/98 (28%), Positives = 52/98 (53%)

Query: 802 NPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVN 861
           N +  L  +S  G  ++V+ ++           +G+T LH A  +GH ++V+ L++ G  
Sbjct: 244 NGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAP 303

Query: 862 VNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMT 899
           + A   +G +PLH AA  ++V+  K L++  A V  +T
Sbjct: 304 LLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVT 341



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 27/86 (31%), Positives = 44/86 (51%)

Query: 814 GEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPL 873
           G  ++V  ++     P + N  G TALH A  AG  E+V+ L++ G  V+A   +  TPL
Sbjct: 421 GHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPL 480

Query: 874 HCAASCNNVQVCKFLVESGAAVFAMT 899
           H A+     ++ + L++  A   A T
Sbjct: 481 HIASRLGKTEIVQLLLQHMAHPDAAT 506



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 23/66 (34%), Positives = 36/66 (54%)

Query: 828 DPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKF 887
           + ++   +G+T LH A   GHT++V  L+  G N++ +   G T LH AA  + V V   
Sbjct: 633 ETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADI 692

Query: 888 LVESGA 893
           L + GA
Sbjct: 693 LTKHGA 698



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 30/103 (29%), Positives = 51/103 (49%), Gaps = 3/103 (2%)

Query: 810 SSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDG 869
           +S EG  D+V  ++ +  +  +    G+T+LH A       +   L + G + +A    G
Sbjct: 648 ASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLG 707

Query: 870 WTPLHCAASCNNVQVCKFLVESGAAVFAMT---YSDMQTAADK 909
           +TPL  A    NV++  FL++ GA V A T   Y+ +  AA +
Sbjct: 708 YTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQ 750



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 25/64 (39%), Positives = 36/64 (56%)

Query: 836 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAV 895
           G T L  A   G+ ++V FL++ G NVNA   +G+TPLH AA   +  +   L++ GA  
Sbjct: 707 GYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKP 766

Query: 896 FAMT 899
            A T
Sbjct: 767 NATT 770



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 24/64 (37%), Positives = 35/64 (54%)

Query: 834 DEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 893
           + G+T +H A   GH  IV  L+Q G + +  +  G T LH AA    V+V + L+ +GA
Sbjct: 408 ESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGA 467

Query: 894 AVFA 897
            V A
Sbjct: 468 LVDA 471



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 29/108 (26%), Positives = 51/108 (47%), Gaps = 5/108 (4%)

Query: 794 AHGMRVK--FNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEI 851
           AH +  K  F PL +   ++  G  D+ + ++            G+T LH A    + ++
Sbjct: 534 AHSLATKKGFTPLHV---AAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKV 590

Query: 852 VKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMT 899
              L++ G + +A   +G+TPLH AA  N +Q+   L+  GA    +T
Sbjct: 591 ALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVT 638



 Score = 43.9 bits (102), Expect = 8e-04
 Identities = 20/81 (24%), Positives = 44/81 (54%)

Query: 814 GEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPL 873
           G + + + ++ +  +P+     G T LH A      ++++ LV++G ++ A    G TP+
Sbjct: 355 GHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPI 414

Query: 874 HCAASCNNVQVCKFLVESGAA 894
           H AA   ++ +   L+++GA+
Sbjct: 415 HVAAFMGHLNIVLLLLQNGAS 435



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 27/78 (34%), Positives = 38/78 (48%), Gaps = 1/78 (1%)

Query: 817 DLVQRIIYEVDDPSLPNDE-GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHC 875
           D V  ++ E   P L   + G++ LH A    H E VK L+Q    V+    D  T LH 
Sbjct: 291 DQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHV 350

Query: 876 AASCNNVQVCKFLVESGA 893
           AA C + +V K L++  A
Sbjct: 351 AAHCGHYRVTKLLLDKRA 368



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 21/66 (31%), Positives = 32/66 (48%)

Query: 834 DEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 893
           + G T LH A   G+  +   L+  G  V+    +G TPLH A+   N  + K L++ G 
Sbjct: 210 ESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGG 269

Query: 894 AVFAMT 899
            + A T
Sbjct: 270 QIDAKT 275



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 28/100 (28%), Positives = 46/100 (46%), Gaps = 4/100 (4%)

Query: 785 LRKTGSERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAV 844
           L K G+++ AH  ++ + PL +       G   +V  ++ +  + +     G T LH A 
Sbjct: 693 LTKHGADQDAH-TKLGYTPLIVACHY---GNVKMVNFLLKQGANVNAKTKNGYTPLHQAA 748

Query: 845 CAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQV 884
             GHT I+  L+Q G   NA  ++G T L  A     + V
Sbjct: 749 QQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISV 788



 Score = 39.3 bits (90), Expect = 0.019
 Identities = 21/75 (28%), Positives = 31/75 (41%)

Query: 829 PSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFL 888
           P      G T LH A      +I   L+ +G   N     G TPLH A+   +  +   L
Sbjct: 601 PHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLL 660

Query: 889 VESGAAVFAMTYSDM 903
           ++ GA +   T S +
Sbjct: 661 LDKGANIHMSTKSGL 675



 Score = 38.1 bits (87), Expect = 0.042
 Identities = 34/132 (25%), Positives = 49/132 (37%), Gaps = 40/132 (30%)

Query: 801 FNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFL----- 855
           F PL +   ++ E   D+V+ ++    + S   ++G T L  A+  GH + V  L     
Sbjct: 110 FTPLYM---AAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDT 166

Query: 856 --------------------------------VQFGVNVNAADSDGWTPLHCAASCNNVQ 883
                                           VQ  + VN     G+TPLH AA   NV 
Sbjct: 167 KGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVN 226

Query: 884 VCKFLVESGAAV 895
           V   L+  GAAV
Sbjct: 227 VATLLLNRGAAV 238


>gi|52426737 ankyrin 2 isoform 2 [Homo sapiens]
          Length = 1872

 Score = 68.6 bits (166), Expect = 3e-11
 Identities = 38/92 (41%), Positives = 54/92 (58%)

Query: 802 NPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVN 861
           N L  L  ++ EG   LVQ ++           +G TALH A  AG  E+VK LV+ G N
Sbjct: 63  NGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGAN 122

Query: 862 VNAADSDGWTPLHCAASCNNVQVCKFLVESGA 893
           +NA   +G+TPL+ AA  N++ V K+L+E+GA
Sbjct: 123 INAQSQNGFTPLYMAAQENHIDVVKYLLENGA 154



 Score = 57.0 bits (136), Expect = 9e-08
 Identities = 30/64 (46%), Positives = 39/64 (60%)

Query: 836 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAV 895
           GIT LH A   G+T +VK L+  G  ++A   DG TPLHCAA   + QV + L+E GA +
Sbjct: 266 GITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPL 325

Query: 896 FAMT 899
            A T
Sbjct: 326 LART 329



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 31/78 (39%), Positives = 46/78 (58%), Gaps = 3/78 (3%)

Query: 826 VDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVC 885
           VDD +L   + +TALH A   GH  + K L+    N NA   +G+TPLH A   N ++V 
Sbjct: 358 VDDVTL---DYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVM 414

Query: 886 KFLVESGAAVFAMTYSDM 903
           + LV+ GA++ A+T S +
Sbjct: 415 ELLVKYGASIQAITESGL 432



 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 38/122 (31%), Positives = 58/122 (47%), Gaps = 3/122 (2%)

Query: 791 ERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTE 850
           + +AH      N    L  S+ EG+ D+   ++      SL   +G T LH A   G  +
Sbjct: 518 QHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLD 577

Query: 851 IVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMT---YSDMQTAA 907
           + K L+Q     ++A  +G TPLH AA  +N +V   L+E GA+  A     Y+ +  AA
Sbjct: 578 VAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAA 637

Query: 908 DK 909
            K
Sbjct: 638 KK 639



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 25/82 (30%), Positives = 46/82 (56%)

Query: 810 SSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDG 869
           +SL G+ ++V+ ++ E  + +  +  G T L+ A    H ++VK+L++ G N + A  DG
Sbjct: 104 ASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDG 163

Query: 870 WTPLHCAASCNNVQVCKFLVES 891
           +TPL  A    + Q    L+E+
Sbjct: 164 FTPLAVALQQGHNQAVAILLEN 185



 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 26/57 (45%), Positives = 36/57 (63%)

Query: 838 TALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAA 894
           T LH A   G TEIV+ L+Q   + +AA ++G+TPLH +A    V V   L+E+GAA
Sbjct: 499 TPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAA 555



 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 24/81 (29%), Positives = 41/81 (50%)

Query: 814 GEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPL 873
           G+ ++VQ ++  +  P      G T LH +   G  ++   L++ G   + A   G+TPL
Sbjct: 508 GKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPL 567

Query: 874 HCAASCNNVQVCKFLVESGAA 894
           H AA   ++ V K L++  AA
Sbjct: 568 HVAAKYGSLDVAKLLLQRRAA 588



 Score = 47.4 bits (111), Expect = 7e-05
 Identities = 28/98 (28%), Positives = 52/98 (53%)

Query: 802 NPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVN 861
           N +  L  +S  G  ++V+ ++           +G+T LH A  +GH ++V+ L++ G  
Sbjct: 265 NGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAP 324

Query: 862 VNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMT 899
           + A   +G +PLH AA  ++V+  K L++  A V  +T
Sbjct: 325 LLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVT 362



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 27/86 (31%), Positives = 44/86 (51%)

Query: 814 GEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPL 873
           G  ++V  ++     P + N  G TALH A  AG  E+V+ L++ G  V+A   +  TPL
Sbjct: 442 GHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPL 501

Query: 874 HCAASCNNVQVCKFLVESGAAVFAMT 899
           H A+     ++ + L++  A   A T
Sbjct: 502 HIASRLGKTEIVQLLLQHMAHPDAAT 527



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 23/66 (34%), Positives = 36/66 (54%)

Query: 828 DPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKF 887
           + ++   +G+T LH A   GHT++V  L+  G N++ +   G T LH AA  + V V   
Sbjct: 654 ETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADI 713

Query: 888 LVESGA 893
           L + GA
Sbjct: 714 LTKHGA 719



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 30/103 (29%), Positives = 51/103 (49%), Gaps = 3/103 (2%)

Query: 810 SSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDG 869
           +S EG  D+V  ++ +  +  +    G+T+LH A       +   L + G + +A    G
Sbjct: 669 ASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLG 728

Query: 870 WTPLHCAASCNNVQVCKFLVESGAAVFAMT---YSDMQTAADK 909
           +TPL  A    NV++  FL++ GA V A T   Y+ +  AA +
Sbjct: 729 YTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQ 771



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 25/64 (39%), Positives = 36/64 (56%)

Query: 836 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAV 895
           G T L  A   G+ ++V FL++ G NVNA   +G+TPLH AA   +  +   L++ GA  
Sbjct: 728 GYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKP 787

Query: 896 FAMT 899
            A T
Sbjct: 788 NATT 791



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 24/64 (37%), Positives = 35/64 (54%)

Query: 834 DEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 893
           + G+T +H A   GH  IV  L+Q G + +  +  G T LH AA    V+V + L+ +GA
Sbjct: 429 ESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGA 488

Query: 894 AVFA 897
            V A
Sbjct: 489 LVDA 492



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 29/108 (26%), Positives = 51/108 (47%), Gaps = 5/108 (4%)

Query: 794 AHGMRVK--FNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEI 851
           AH +  K  F PL +   ++  G  D+ + ++            G+T LH A    + ++
Sbjct: 555 AHSLATKKGFTPLHV---AAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKV 611

Query: 852 VKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMT 899
              L++ G + +A   +G+TPLH AA  N +Q+   L+  GA    +T
Sbjct: 612 ALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVT 659



 Score = 43.9 bits (102), Expect = 8e-04
 Identities = 20/81 (24%), Positives = 44/81 (54%)

Query: 814 GEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPL 873
           G + + + ++ +  +P+     G T LH A      ++++ LV++G ++ A    G TP+
Sbjct: 376 GHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPI 435

Query: 874 HCAASCNNVQVCKFLVESGAA 894
           H AA   ++ +   L+++GA+
Sbjct: 436 HVAAFMGHLNIVLLLLQNGAS 456



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 27/78 (34%), Positives = 38/78 (48%), Gaps = 1/78 (1%)

Query: 817 DLVQRIIYEVDDPSLPNDE-GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHC 875
           D V  ++ E   P L   + G++ LH A    H E VK L+Q    V+    D  T LH 
Sbjct: 312 DQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHV 371

Query: 876 AASCNNVQVCKFLVESGA 893
           AA C + +V K L++  A
Sbjct: 372 AAHCGHYRVTKLLLDKRA 389



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 21/66 (31%), Positives = 32/66 (48%)

Query: 834 DEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 893
           + G T LH A   G+  +   L+  G  V+    +G TPLH A+   N  + K L++ G 
Sbjct: 231 ESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGG 290

Query: 894 AVFAMT 899
            + A T
Sbjct: 291 QIDAKT 296



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 28/100 (28%), Positives = 46/100 (46%), Gaps = 4/100 (4%)

Query: 785 LRKTGSERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAV 844
           L K G+++ AH  ++ + PL +       G   +V  ++ +  + +     G T LH A 
Sbjct: 714 LTKHGADQDAH-TKLGYTPLIVACHY---GNVKMVNFLLKQGANVNAKTKNGYTPLHQAA 769

Query: 845 CAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQV 884
             GHT I+  L+Q G   NA  ++G T L  A     + V
Sbjct: 770 QQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISV 809



 Score = 39.3 bits (90), Expect = 0.019
 Identities = 21/75 (28%), Positives = 31/75 (41%)

Query: 829 PSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFL 888
           P      G T LH A      +I   L+ +G   N     G TPLH A+   +  +   L
Sbjct: 622 PHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLL 681

Query: 889 VESGAAVFAMTYSDM 903
           ++ GA +   T S +
Sbjct: 682 LDKGANIHMSTKSGL 696



 Score = 38.1 bits (87), Expect = 0.042
 Identities = 34/132 (25%), Positives = 49/132 (37%), Gaps = 40/132 (30%)

Query: 801 FNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFL----- 855
           F PL +   ++ E   D+V+ ++    + S   ++G T L  A+  GH + V  L     
Sbjct: 131 FTPLYM---AAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDT 187

Query: 856 --------------------------------VQFGVNVNAADSDGWTPLHCAASCNNVQ 883
                                           VQ  + VN     G+TPLH AA   NV 
Sbjct: 188 KGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVN 247

Query: 884 VCKFLVESGAAV 895
           V   L+  GAAV
Sbjct: 248 VATLLLNRGAAV 259


>gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]
          Length = 3957

 Score = 68.6 bits (166), Expect = 3e-11
 Identities = 38/92 (41%), Positives = 54/92 (58%)

Query: 802 NPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVN 861
           N L  L  ++ EG   LVQ ++           +G TALH A  AG  E+VK LV+ G N
Sbjct: 63  NGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGAN 122

Query: 862 VNAADSDGWTPLHCAASCNNVQVCKFLVESGA 893
           +NA   +G+TPL+ AA  N++ V K+L+E+GA
Sbjct: 123 INAQSQNGFTPLYMAAQENHIDVVKYLLENGA 154



 Score = 57.0 bits (136), Expect = 9e-08
 Identities = 30/64 (46%), Positives = 39/64 (60%)

Query: 836 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAV 895
           GIT LH A   G+T +VK L+  G  ++A   DG TPLHCAA   + QV + L+E GA +
Sbjct: 266 GITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPL 325

Query: 896 FAMT 899
            A T
Sbjct: 326 LART 329



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 31/78 (39%), Positives = 46/78 (58%), Gaps = 3/78 (3%)

Query: 826 VDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVC 885
           VDD +L   + +TALH A   GH  + K L+    N NA   +G+TPLH A   N ++V 
Sbjct: 358 VDDVTL---DYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVM 414

Query: 886 KFLVESGAAVFAMTYSDM 903
           + LV+ GA++ A+T S +
Sbjct: 415 ELLVKYGASIQAITESGL 432



 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 38/122 (31%), Positives = 58/122 (47%), Gaps = 3/122 (2%)

Query: 791 ERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTE 850
           + +AH      N    L  S+ EG+ D+   ++      SL   +G T LH A   G  +
Sbjct: 518 QHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLD 577

Query: 851 IVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMT---YSDMQTAA 907
           + K L+Q     ++A  +G TPLH AA  +N +V   L+E GA+  A     Y+ +  AA
Sbjct: 578 VAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAA 637

Query: 908 DK 909
            K
Sbjct: 638 KK 639



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 25/82 (30%), Positives = 46/82 (56%)

Query: 810 SSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDG 869
           +SL G+ ++V+ ++ E  + +  +  G T L+ A    H ++VK+L++ G N + A  DG
Sbjct: 104 ASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDG 163

Query: 870 WTPLHCAASCNNVQVCKFLVES 891
           +TPL  A    + Q    L+E+
Sbjct: 164 FTPLAVALQQGHNQAVAILLEN 185



 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 26/57 (45%), Positives = 36/57 (63%)

Query: 838 TALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAA 894
           T LH A   G TEIV+ L+Q   + +AA ++G+TPLH +A    V V   L+E+GAA
Sbjct: 499 TPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAA 555



 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 24/81 (29%), Positives = 41/81 (50%)

Query: 814 GEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPL 873
           G+ ++VQ ++  +  P      G T LH +   G  ++   L++ G   + A   G+TPL
Sbjct: 508 GKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPL 567

Query: 874 HCAASCNNVQVCKFLVESGAA 894
           H AA   ++ V K L++  AA
Sbjct: 568 HVAAKYGSLDVAKLLLQRRAA 588



 Score = 47.4 bits (111), Expect = 7e-05
 Identities = 28/98 (28%), Positives = 52/98 (53%)

Query: 802 NPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVN 861
           N +  L  +S  G  ++V+ ++           +G+T LH A  +GH ++V+ L++ G  
Sbjct: 265 NGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAP 324

Query: 862 VNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMT 899
           + A   +G +PLH AA  ++V+  K L++  A V  +T
Sbjct: 325 LLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVT 362



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 27/86 (31%), Positives = 44/86 (51%)

Query: 814 GEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPL 873
           G  ++V  ++     P + N  G TALH A  AG  E+V+ L++ G  V+A   +  TPL
Sbjct: 442 GHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPL 501

Query: 874 HCAASCNNVQVCKFLVESGAAVFAMT 899
           H A+     ++ + L++  A   A T
Sbjct: 502 HIASRLGKTEIVQLLLQHMAHPDAAT 527



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 23/66 (34%), Positives = 36/66 (54%)

Query: 828 DPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKF 887
           + ++   +G+T LH A   GHT++V  L+  G N++ +   G T LH AA  + V V   
Sbjct: 654 ETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADI 713

Query: 888 LVESGA 893
           L + GA
Sbjct: 714 LTKHGA 719



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 30/103 (29%), Positives = 51/103 (49%), Gaps = 3/103 (2%)

Query: 810 SSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDG 869
           +S EG  D+V  ++ +  +  +    G+T+LH A       +   L + G + +A    G
Sbjct: 669 ASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLG 728

Query: 870 WTPLHCAASCNNVQVCKFLVESGAAVFAMT---YSDMQTAADK 909
           +TPL  A    NV++  FL++ GA V A T   Y+ +  AA +
Sbjct: 729 YTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQ 771



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 25/64 (39%), Positives = 36/64 (56%)

Query: 836 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAV 895
           G T L  A   G+ ++V FL++ G NVNA   +G+TPLH AA   +  +   L++ GA  
Sbjct: 728 GYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKP 787

Query: 896 FAMT 899
            A T
Sbjct: 788 NATT 791



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 24/64 (37%), Positives = 35/64 (54%)

Query: 834 DEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 893
           + G+T +H A   GH  IV  L+Q G + +  +  G T LH AA    V+V + L+ +GA
Sbjct: 429 ESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGA 488

Query: 894 AVFA 897
            V A
Sbjct: 489 LVDA 492



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 29/108 (26%), Positives = 51/108 (47%), Gaps = 5/108 (4%)

Query: 794 AHGMRVK--FNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEI 851
           AH +  K  F PL +   ++  G  D+ + ++            G+T LH A    + ++
Sbjct: 555 AHSLATKKGFTPLHV---AAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKV 611

Query: 852 VKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMT 899
              L++ G + +A   +G+TPLH AA  N +Q+   L+  GA    +T
Sbjct: 612 ALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVT 659



 Score = 43.9 bits (102), Expect = 8e-04
 Identities = 20/81 (24%), Positives = 44/81 (54%)

Query: 814 GEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPL 873
           G + + + ++ +  +P+     G T LH A      ++++ LV++G ++ A    G TP+
Sbjct: 376 GHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPI 435

Query: 874 HCAASCNNVQVCKFLVESGAA 894
           H AA   ++ +   L+++GA+
Sbjct: 436 HVAAFMGHLNIVLLLLQNGAS 456



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 27/78 (34%), Positives = 38/78 (48%), Gaps = 1/78 (1%)

Query: 817 DLVQRIIYEVDDPSLPNDE-GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHC 875
           D V  ++ E   P L   + G++ LH A    H E VK L+Q    V+    D  T LH 
Sbjct: 312 DQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHV 371

Query: 876 AASCNNVQVCKFLVESGA 893
           AA C + +V K L++  A
Sbjct: 372 AAHCGHYRVTKLLLDKRA 389



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 21/66 (31%), Positives = 32/66 (48%)

Query: 834 DEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 893
           + G T LH A   G+  +   L+  G  V+    +G TPLH A+   N  + K L++ G 
Sbjct: 231 ESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGG 290

Query: 894 AVFAMT 899
            + A T
Sbjct: 291 QIDAKT 296



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 28/100 (28%), Positives = 46/100 (46%), Gaps = 4/100 (4%)

Query: 785 LRKTGSERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAV 844
           L K G+++ AH  ++ + PL +       G   +V  ++ +  + +     G T LH A 
Sbjct: 714 LTKHGADQDAH-TKLGYTPLIVACHY---GNVKMVNFLLKQGANVNAKTKNGYTPLHQAA 769

Query: 845 CAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQV 884
             GHT I+  L+Q G   NA  ++G T L  A     + V
Sbjct: 770 QQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISV 809



 Score = 39.3 bits (90), Expect = 0.019
 Identities = 21/75 (28%), Positives = 31/75 (41%)

Query: 829 PSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFL 888
           P      G T LH A      +I   L+ +G   N     G TPLH A+   +  +   L
Sbjct: 622 PHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLL 681

Query: 889 VESGAAVFAMTYSDM 903
           ++ GA +   T S +
Sbjct: 682 LDKGANIHMSTKSGL 696



 Score = 38.1 bits (87), Expect = 0.042
 Identities = 34/132 (25%), Positives = 49/132 (37%), Gaps = 40/132 (30%)

Query: 801 FNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFL----- 855
           F PL +   ++ E   D+V+ ++    + S   ++G T L  A+  GH + V  L     
Sbjct: 131 FTPLYM---AAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDT 187

Query: 856 --------------------------------VQFGVNVNAADSDGWTPLHCAASCNNVQ 883
                                           VQ  + VN     G+TPLH AA   NV 
Sbjct: 188 KGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVN 247

Query: 884 VCKFLVESGAAV 895
           V   L+  GAAV
Sbjct: 248 VATLLLNRGAAV 259



 Score = 33.9 bits (76), Expect = 0.79
 Identities = 75/392 (19%), Positives = 148/392 (37%), Gaps = 52/392 (13%)

Query: 299  PSQGSASVPQSTGNALDQVDDGEVPLREKEKKVRPFSMFDAVD---QSNAPPSFGTLRKN 355
            P    A  P   G    + +    P   +E K+   +   A+D   +S A  SF   +  
Sbjct: 3080 PDTTPARTPTEEGTPTSEQN----PFLFQEGKLFEMTRSGAIDMTKRSYADESFHFFQIG 3135

Query: 356  QSSEDILRDAQVANKNVAKVPPPVPTKPKQINLPYFGQTNQPPSDIKPDGSSQQLSTVVP 415
            Q S +      V        P P+ T  + + L    +T    +D+ PD  S+++  +  
Sbjct: 3136 QESREETLSEDVKEGATGADPLPLETSAESLALSESKETVDDEADLLPDDVSEEVEEIPA 3195

Query: 416  SMGTKPKPAGQQPRVLLSPSIPSVGQDQTLSPGSKQ-------ESPPAAAVRPFTPQPSK 468
            S          Q  +  S   P+    + +S G+K        + PP + V+  +   S 
Sbjct: 3196 S----DAQLNSQMGISASTETPT---KEAVSVGTKDLPTVQTGDIPPLSGVKQISCPDSS 3248

Query: 469  DTLLPPFRKPQTVAASSIYSMYTQQQAPGKNFQQAVQSAL-------------TKTHTRG 515
            +    P  + Q   ++   S+Y+ +     +     Q ++             T++ ++ 
Sbjct: 3249 E----PAVQVQLDFSTLTRSVYSDRGDDSPDSSPEEQKSVIEIPTAPMENVPFTESKSKI 3304

Query: 516  PHFSSVYGKPVIAAAQNQQQHPENIYSN-------SQGKPGSPEPETEPVSSVQE--NHE 566
            P  +     P   +A+ +    E+  S+        + KP S  P   P+  V++  +  
Sbjct: 3305 PVRTMPTSTPAPPSAEYESSVSEDFLSSVDEENKADEAKPKSKLPVKVPLQRVEQQLSDL 3364

Query: 567  NERIPRPLSPT-KLLPFLSNPYRNQSDADLEALRKKLSNAPRPLKKRSSITEPEGPNGPN 625
            +  + + ++P  + +  ++   R++S++D  +L  K      P+K R S TE E  +   
Sbjct: 3365 DTSVQKTVAPQGQDMASIAPDNRSKSESDASSLDSK---TKCPVKTR-SYTETETESRER 3420

Query: 626  IQKLLYQRTTIAAMETISVPSYPSKSASVTAS 657
             ++L  +    A    I     P KS S T+S
Sbjct: 3421 AEELELESEEGATRPKILTSRLPVKSRSTTSS 3452



 Score = 33.5 bits (75), Expect = 1.0
 Identities = 46/186 (24%), Positives = 74/186 (39%), Gaps = 26/186 (13%)

Query: 400  DIKPDGSSQQLSTVVPSMGTKPKPAGQ---QPRVLLSPSIPSVGQDQTLSPGSKQES--- 453
            DI PD +        PS+G K KP  +   + +      + +  +   L  GS +ES   
Sbjct: 1681 DIPPDETQSTQKQHKPSLGIK-KPVRRKLKEKQKQKEEGLQASAEKAELKKGSSEESLGE 1739

Query: 454  PPAAAVRPFTPQPSKDTLLPPFRKPQTVAASSIYSMYTQQQAPGKNFQQAVQSALTKTHT 513
             P  A  P     +   L         +  + I S+  + +A  K  +   Q   +K   
Sbjct: 1740 DPGLAPEPLPTVKATSPL---------IEETPIGSIKDKVKALQKRVEDE-QKGRSKLPI 1789

Query: 514  RGPHFSSVYGKPVIAAAQNQQQHPENIYS--NSQGKPGSPEPETEPVSSVQENHENERIP 571
            R      V GK  +      + HP    S  + +  PGSP P+TE  S++  + + ER P
Sbjct: 1790 R------VKGKEDVPKKTTHRPHPAASPSLKSERHAPGSPSPKTERHSTLSSSAKTERHP 1843

Query: 572  RPLSPT 577
             P+SP+
Sbjct: 1844 -PVSPS 1848


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 68.2 bits (165), Expect = 4e-11
 Identities = 108/490 (22%), Positives = 175/490 (35%), Gaps = 78/490 (15%)

Query: 343 SNAPPSFGTLRKNQSSEDILR----DAQVANKNVAKVPPPVPTKPKQINLPYFGQTNQPP 398
           S+A P     R   S+    R     +Q   K +  + PP  T P++   P  G  +  P
Sbjct: 244 SSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP 303

Query: 399 SDIKPDGSSQQLSTVVPSMGTKPKPAGQQPRVLL---------SPSIPSVGQDQTLSPGS 449
                   ++      P     P PA   P   L         SPS P   Q     P +
Sbjct: 304 LATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPAT 363

Query: 450 K-QESPPAAAVRPFTPQPSKDTLLPPFRKPQTVAASSIYSMYTQQQAPGKNFQQAVQSAL 508
              ++PP+    P    PS  T+ PP + P ++ + S+       QAP      A+ S  
Sbjct: 364 PPSQAPPSMTTPPMQAPPSLQTI-PPIQVPHSLTSPSL-------QAPPSPL--ALSSLQ 413

Query: 509 TKTHTRGPHFSSVYGKPVIAAAQNQQQHPENIYSNSQGKPGSPEPETEPVSSVQENHENE 568
             T    P   + +    ++  Q Q          S  +P S  P++ P+ +      + 
Sbjct: 414 ATTSLGSPTLQATHSFLTMSPRQTQAS------LTSPSRPASTPPDSPPLQAPLSLPASP 467

Query: 569 RIPRPLSPTKLLPFLSNPYRNQSDADLEALRKKLSNAPR---------PLKKRSSITEPE 619
            +   LSP   +  LS+P        L+AL    S++P+         PL+ +SS+  P 
Sbjct: 468 PLQTSLSPA--VSPLSSPLTIHP---LQALSSLASHSPQAPLSSLIMPPLETQSSLAPPS 522

Query: 620 GPNGPNIQKLLYQRTTIAAMETISVPSYPSKSASVTASS------ESPVEIQ---NPYLH 670
               P           +  + +++ P   + SA +T          +P  +Q   +P   
Sbjct: 523 LQTPP----ASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTT 578

Query: 671 VEPEKEVVSLVPESLSPEDVGNASTENSDMPAPSPGLDYEPEGVPDNS-PNLQNNPEEP- 728
             PE       P   +P  + +   +    P  SP     P+  P  + P LQ  P  P 
Sbjct: 579 PPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPA 638

Query: 729 ----------NPEAPHVLDVYLEEYPPYPPP------PY--PSGEPEGPGEDSVSMRPPE 770
                     +P+AP+ L V+L + P  PPP      P+  P+  P  P     S  PP 
Sbjct: 639 SPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPS 698

Query: 771 ITG-QVSLPP 779
           +    + +PP
Sbjct: 699 LAAPPLQVPP 708



 Score = 34.7 bits (78), Expect = 0.46
 Identities = 121/589 (20%), Positives = 179/589 (30%), Gaps = 82/589 (13%)

Query: 203  PVSSDGNLPQQAASAPSRVAAVGPYIQSSTMPRMPSRPELLVKPALPDGSLVIQASEGPM 262
            P+ +  +L   +   P       P      +P +   P       L    L       P 
Sbjct: 511  PLETQSSLAPPSLQTPPASLTTPPL---ENLPSLAPPPLQTASAPLTTPHLETPPCPAPC 567

Query: 263  KIQTLPNMRSGAASQTKGSKIHPVGPDWSPSNADLFPSQGSASVPQSTGNALDQVDDGEV 322
             +Q  P+  +    +T  S   P  P  +P      P QG  S P S             
Sbjct: 568  PLQAPPSPLTTPPPETPSSIATP--PPQAPPALASPPLQGLPSPPLS------------- 612

Query: 323  PLREKEKKVRPFSMFDAVDQSNAPPSFGTLRKNQSSEDILRDAQVANKNVAKVPPPVPTK 382
            PL     +  P      +    +PP+   L    +      +A   +   A   PP P+ 
Sbjct: 613  PLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP-PSP 671

Query: 383  PKQINLPYFGQTNQPPSDIKPDGSSQQLSTVVPSMGTKPKPAGQQPRVLLSPSIPSVGQD 442
            P Q   P+    + P S      S    S   P +   P P          P+ P +   
Sbjct: 672  PVQA--PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP----------PASPPMSPS 719

Query: 443  QTLSPGSKQESPPAAAVRPFTPQPSKDTLLPPFRKPQTVAASSIYSMYTQQQAPGKNFQQ 502
             T  P    ++PP  A  P    PS     PP   P + +A+    +     AP      
Sbjct: 720  ATPPP----QAPPPLAAPPLQVPPS-----PPASPPMSPSATPPPRVPPLLAAPPLQVPP 770

Query: 503  AVQSALTKTHTRGPHFSSVYGKPVIAAAQNQQQHPENIYSNSQGKPGSPEPETEPVSSVQ 562
            +  ++L  +    P   +    P   A    Q  P    S     P SP     P+S + 
Sbjct: 771  SPPASLPMSPLAKPPPQA----PPALATPPLQALPSPPASFPGQAPFSPSASL-PMSPL- 824

Query: 563  ENHENERIPRPLSPTKL-LPFLSNPYRNQSDADLEALRKKLSNAPRPLKKRSSITEPEGP 621
                    P P +P  L  P L  P    +   L+A R+  +  P        +T    P
Sbjct: 825  ------ATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP 878

Query: 622  NGPNIQKLLYQRTTIAAMETISVPSYPSKSASVTASSESPVEIQNPYLHVEPEKEVVSLV 681
              P          + +   T+S P     S+S T+   +P E++       PE    +  
Sbjct: 879  GPP-------PPPSRSPSSTLSGPDLAGHSSSATS---TPEELRG--YDSGPEGGAAASP 926

Query: 682  PESLSPEDVGNASTENSDMP------APSPGLDYEPEGVPDNSPNLQNNPEEPNPE---- 731
            P          A+      P      AP   L + P   P ++  L    E   PE    
Sbjct: 927  PPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATP 986

Query: 732  APHVLDVYLEEYPPYPPPPYPSGEPEGPGEDSVSMRPPEITGQVSLPPG 780
            AP  LD       P P P    G+         S R P+      LP G
Sbjct: 987  APGALD-------PGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLG 1028


>gi|4506217 proteasome 26S non-ATPase subunit 10 isoform 1 [Homo
           sapiens]
          Length = 226

 Score = 67.4 bits (163), Expect = 6e-11
 Identities = 36/82 (43%), Positives = 50/82 (60%)

Query: 817 DLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCA 876
           +L + I+ +    +  + +  TALH A  AGHTEIV+FL+Q GV VN  D  GW+PLH A
Sbjct: 21  ELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIA 80

Query: 877 ASCNNVQVCKFLVESGAAVFAM 898
           AS    ++ K L+  GA V A+
Sbjct: 81  ASAGRDEIVKALLGKGAQVNAV 102



 Score = 54.3 bits (129), Expect = 6e-07
 Identities = 29/61 (47%), Positives = 37/61 (60%)

Query: 833 NDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESG 892
           +D G + LH A  AG  EIVK L+  G  VNA + +G TPLH AAS N  ++   L+E G
Sbjct: 70  DDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGG 129

Query: 893 A 893
           A
Sbjct: 130 A 130



 Score = 47.4 bits (111), Expect = 7e-05
 Identities = 21/69 (30%), Positives = 37/69 (53%)

Query: 828 DPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKF 887
           +P   +    TA+H A   G+ +++  L+ +  + N  D++G TPLH A     V+  K 
Sbjct: 131 NPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKL 190

Query: 888 LVESGAAVF 896
           LV  GA+++
Sbjct: 191 LVSQGASIY 199



 Score = 30.8 bits (68), Expect = 6.7
 Identities = 17/67 (25%), Positives = 31/67 (46%)

Query: 810 SSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDG 869
           ++ +G   ++  ++Y     ++ + EG T LH A      E  K LV  G ++   + + 
Sbjct: 146 AAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEE 205

Query: 870 WTPLHCA 876
            TPL  A
Sbjct: 206 KTPLQVA 212


>gi|28605137 proteasome 26S non-ATPase subunit 10 isform 2 [Homo
           sapiens]
          Length = 151

 Score = 67.4 bits (163), Expect = 6e-11
 Identities = 36/82 (43%), Positives = 50/82 (60%)

Query: 817 DLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCA 876
           +L + I+ +    +  + +  TALH A  AGHTEIV+FL+Q GV VN  D  GW+PLH A
Sbjct: 21  ELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIA 80

Query: 877 ASCNNVQVCKFLVESGAAVFAM 898
           AS    ++ K L+  GA V A+
Sbjct: 81  ASAGRDEIVKALLGKGAQVNAV 102



 Score = 54.3 bits (129), Expect = 6e-07
 Identities = 29/61 (47%), Positives = 37/61 (60%)

Query: 833 NDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESG 892
           +D G + LH A  AG  EIVK L+  G  VNA + +G TPLH AAS N  ++   L+E G
Sbjct: 70  DDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGG 129

Query: 893 A 893
           A
Sbjct: 130 A 130



 Score = 32.0 bits (71), Expect = 3.0
 Identities = 19/65 (29%), Positives = 31/65 (47%)

Query: 814 GEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPL 873
           G  ++V+ ++ +    +  N  G T LH A      EI   L++ G N +A D    T +
Sbjct: 84  GRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAM 143

Query: 874 HCAAS 878
           H AA+
Sbjct: 144 HRAAA 148


>gi|215598574 ankyrin 1 isoform 9 [Homo sapiens]
          Length = 1897

 Score = 67.0 bits (162), Expect = 8e-11
 Identities = 35/84 (41%), Positives = 52/84 (61%)

Query: 810 SSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDG 869
           +S EG   +V  ++++         +G TALH A  AG  E+V+ LV +G NVNA    G
Sbjct: 85  ASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKG 144

Query: 870 WTPLHCAASCNNVQVCKFLVESGA 893
           +TPL+ AA  N+++V KFL+E+GA
Sbjct: 145 FTPLYMAAQENHLEVVKFLLENGA 168



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 32/84 (38%), Positives = 47/84 (55%)

Query: 810 SSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDG 869
           +S  G   +V+ ++     P++ N +  T LH A  AGHTE+ K+L+Q    VNA   D 
Sbjct: 444 ASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDD 503

Query: 870 WTPLHCAASCNNVQVCKFLVESGA 893
            TPLHCAA   +  + K L+E+ A
Sbjct: 504 QTPLHCAARIGHTNMVKLLLENNA 527



 Score = 60.5 bits (145), Expect = 8e-09
 Identities = 34/100 (34%), Positives = 55/100 (55%), Gaps = 3/100 (3%)

Query: 813 EGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTP 872
           EG  ++V  ++ +  + +L N  G+T LH     GH  +   L++ GV V+A    G+TP
Sbjct: 678 EGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTP 737

Query: 873 LHCAASCNNVQVCKFLVESGAAVFAMT---YSDMQTAADK 909
           LH A+   N+++ KFL++  A V A T   YS +  AA +
Sbjct: 738 LHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQ 777



 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 29/79 (36%), Positives = 48/79 (60%), Gaps = 3/79 (3%)

Query: 825 EVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQV 884
           E+DD +L +   +T LH A   GH  + K L+  G   N+   +G+TPLH A   N+V+V
Sbjct: 363 EIDDITLDH---LTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRV 419

Query: 885 CKFLVESGAAVFAMTYSDM 903
            + L+++GA++ A+T S +
Sbjct: 420 MELLLKTGASIDAVTESGL 438



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 26/83 (31%), Positives = 45/83 (54%)

Query: 810 SSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDG 869
           ++L G+ ++V+ ++    + +  + +G T L+ A    H E+VKFL++ G N N A  DG
Sbjct: 118 AALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDG 177

Query: 870 WTPLHCAASCNNVQVCKFLVESG 892
           +TPL  A    +  V   L+  G
Sbjct: 178 FTPLAVALQQGHENVVAHLINYG 200



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 27/69 (39%), Positives = 39/69 (56%)

Query: 834 DEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 893
           + G+T LH A   GH  IVK L+Q G + N ++    TPLH AA   + +V K+L+++ A
Sbjct: 435 ESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKA 494

Query: 894 AVFAMTYSD 902
            V A    D
Sbjct: 495 KVNAKAKDD 503



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 35/119 (29%), Positives = 57/119 (47%), Gaps = 4/119 (3%)

Query: 819 VQRIIYEVD-DPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAA 877
           V  ++ E D  P+     G+T LH AV   + +IVK L+  G + ++   +G+TPLH AA
Sbjct: 584 VAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAA 643

Query: 878 SCNNVQVCKFLVESGAAVFAMTYSDMQTAADKCEEMEEGYTQCSQFLYGVQEKMGIMNK 936
             N V+V + L++ G +  A     +Q         +EG+ +    L   Q    + NK
Sbjct: 644 KQNQVEVARSLLQYGGSANA---ESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNK 699



 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 24/64 (37%), Positives = 36/64 (56%)

Query: 836 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAV 895
           GIT LH A   G+  +V+ L+  G  +     D  TPLHCAA   +V++ + L++ GA +
Sbjct: 272 GITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPI 331

Query: 896 FAMT 899
            A T
Sbjct: 332 QAKT 335



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 31/103 (30%), Positives = 45/103 (43%)

Query: 791 ERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTE 850
           ER AH      N L  L  +      D+V+ ++     P  P   G T LH A      E
Sbjct: 590 ERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVE 649

Query: 851 IVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 893
           + + L+Q+G + NA    G TPLH AA   + ++   L+   A
Sbjct: 650 VARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQA 692



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 25/65 (38%), Positives = 33/65 (50%)

Query: 835 EGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAA 894
           +G+T LH A   GH E+V  L+    N N  +  G TPLH  A   +V V   L++ G  
Sbjct: 667 QGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVM 726

Query: 895 VFAMT 899
           V A T
Sbjct: 727 VDATT 731



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 26/62 (41%), Positives = 34/62 (54%)

Query: 838 TALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFA 897
           T LH A   GHT +VK L++   N N A + G TPLH AA   +V+    L+E  A+   
Sbjct: 505 TPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQAC 564

Query: 898 MT 899
           MT
Sbjct: 565 MT 566



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 24/82 (29%), Positives = 40/82 (48%)

Query: 813 EGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTP 872
           EG  + V  ++ +    +    +G T LH A   G   + + L++   + NAA  +G TP
Sbjct: 546 EGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTP 605

Query: 873 LHCAASCNNVQVCKFLVESGAA 894
           LH A   NN+ + K L+  G +
Sbjct: 606 LHVAVHHNNLDIVKLLLPRGGS 627



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 20/58 (34%), Positives = 33/58 (56%)

Query: 836 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 893
           G++ +H A    H + V+ L+Q+   ++    D  TPLH AA C + +V K L++ GA
Sbjct: 338 GLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGA 395



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 26/80 (32%), Positives = 40/80 (50%)

Query: 814 GEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPL 873
           G  ++V+ ++    +P+L    G T LH A   GH E V  L++   +       G+TPL
Sbjct: 514 GHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPL 573

Query: 874 HCAASCNNVQVCKFLVESGA 893
           H AA    V+V + L+E  A
Sbjct: 574 HVAAKYGKVRVAELLLERDA 593



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 32/102 (31%), Positives = 47/102 (46%), Gaps = 9/102 (8%)

Query: 793 IAHGM------RVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCA 846
           I HG+      R+ + PL +   +S  G   LV+ ++    D +     G + LH A   
Sbjct: 721 IKHGVMVDATTRMGYTPLHV---ASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQ 777

Query: 847 GHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFL 888
           GHT+IV  L++ G + N   SDG TPL  A     + V   L
Sbjct: 778 GHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVL 819



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 23/59 (38%), Positives = 36/59 (61%)

Query: 836 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAA 894
           G T LH A   G+ ++VKFL+Q   +VNA    G++PLH AA   +  +   L+++GA+
Sbjct: 734 GYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGAS 792



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 28/114 (24%), Positives = 55/114 (48%), Gaps = 6/114 (5%)

Query: 826 VDDPSLPNDE---GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNV 882
           +D  + PN     G T LH A    H  +++ L++ G +++A    G TPLH A+   ++
Sbjct: 391 LDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHL 450

Query: 883 QVCKFLVESGAAVFAMTYSDMQTAADKCEEMEEGYTQCSQFLYGVQEKMGIMNK 936
            + K L++ GA   +   S+++           G+T+ +++L   + K+    K
Sbjct: 451 PIVKNLLQRGA---SPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAK 501



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 22/76 (28%), Positives = 39/76 (51%)

Query: 828 DPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKF 887
           +P + +  G T LH A    +  + + L+  G +VN    +G TPLH A+   NV + + 
Sbjct: 231 NPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRL 290

Query: 888 LVESGAAVFAMTYSDM 903
           L++ GA +   T  ++
Sbjct: 291 LLDRGAQIETKTKDEL 306



 Score = 38.9 bits (89), Expect = 0.025
 Identities = 29/95 (30%), Positives = 43/95 (45%), Gaps = 7/95 (7%)

Query: 801 FNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGV 860
           F PLA+ L    +G  ++V  +I    +        + ALH A     T     L+Q   
Sbjct: 178 FTPLAVALQ---QGHENVVAHLI----NYGTKGKVRLPALHIAARNDDTRTAAVLLQNDP 230

Query: 861 NVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAV 895
           N +     G+TPLH AA   N+ V + L+  GA+V
Sbjct: 231 NPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASV 265



 Score = 38.9 bits (89), Expect = 0.025
 Identities = 26/107 (24%), Positives = 48/107 (44%), Gaps = 3/107 (2%)

Query: 796 GMRVKFNP---LALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIV 852
           G  V F P   +  L  +S  G   +V+ ++           + +T LH A   GH  I 
Sbjct: 262 GASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRIS 321

Query: 853 KFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMT 899
           + L+  G  + A   +G +P+H AA  +++   + L++  A +  +T
Sbjct: 322 EILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDIT 368


>gi|70780359 ankyrin 1 isoform 1 [Homo sapiens]
          Length = 1881

 Score = 67.0 bits (162), Expect = 8e-11
 Identities = 35/84 (41%), Positives = 52/84 (61%)

Query: 810 SSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDG 869
           +S EG   +V  ++++         +G TALH A  AG  E+V+ LV +G NVNA    G
Sbjct: 52  ASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKG 111

Query: 870 WTPLHCAASCNNVQVCKFLVESGA 893
           +TPL+ AA  N+++V KFL+E+GA
Sbjct: 112 FTPLYMAAQENHLEVVKFLLENGA 135



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 32/84 (38%), Positives = 47/84 (55%)

Query: 810 SSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDG 869
           +S  G   +V+ ++     P++ N +  T LH A  AGHTE+ K+L+Q    VNA   D 
Sbjct: 411 ASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDD 470

Query: 870 WTPLHCAASCNNVQVCKFLVESGA 893
            TPLHCAA   +  + K L+E+ A
Sbjct: 471 QTPLHCAARIGHTNMVKLLLENNA 494



 Score = 60.5 bits (145), Expect = 8e-09
 Identities = 34/100 (34%), Positives = 55/100 (55%), Gaps = 3/100 (3%)

Query: 813 EGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTP 872
           EG  ++V  ++ +  + +L N  G+T LH     GH  +   L++ GV V+A    G+TP
Sbjct: 645 EGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTP 704

Query: 873 LHCAASCNNVQVCKFLVESGAAVFAMT---YSDMQTAADK 909
           LH A+   N+++ KFL++  A V A T   YS +  AA +
Sbjct: 705 LHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQ 744



 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 29/79 (36%), Positives = 48/79 (60%), Gaps = 3/79 (3%)

Query: 825 EVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQV 884
           E+DD +L +   +T LH A   GH  + K L+  G   N+   +G+TPLH A   N+V+V
Sbjct: 330 EIDDITLDH---LTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRV 386

Query: 885 CKFLVESGAAVFAMTYSDM 903
            + L+++GA++ A+T S +
Sbjct: 387 MELLLKTGASIDAVTESGL 405



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 26/83 (31%), Positives = 45/83 (54%)

Query: 810 SSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDG 869
           ++L G+ ++V+ ++    + +  + +G T L+ A    H E+VKFL++ G N N A  DG
Sbjct: 85  AALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDG 144

Query: 870 WTPLHCAASCNNVQVCKFLVESG 892
           +TPL  A    +  V   L+  G
Sbjct: 145 FTPLAVALQQGHENVVAHLINYG 167



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 27/69 (39%), Positives = 39/69 (56%)

Query: 834 DEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 893
           + G+T LH A   GH  IVK L+Q G + N ++    TPLH AA   + +V K+L+++ A
Sbjct: 402 ESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKA 461

Query: 894 AVFAMTYSD 902
            V A    D
Sbjct: 462 KVNAKAKDD 470



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 35/119 (29%), Positives = 57/119 (47%), Gaps = 4/119 (3%)

Query: 819 VQRIIYEVD-DPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAA 877
           V  ++ E D  P+     G+T LH AV   + +IVK L+  G + ++   +G+TPLH AA
Sbjct: 551 VAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAA 610

Query: 878 SCNNVQVCKFLVESGAAVFAMTYSDMQTAADKCEEMEEGYTQCSQFLYGVQEKMGIMNK 936
             N V+V + L++ G +  A     +Q         +EG+ +    L   Q    + NK
Sbjct: 611 KQNQVEVARSLLQYGGSANA---ESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNK 666



 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 24/64 (37%), Positives = 36/64 (56%)

Query: 836 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAV 895
           GIT LH A   G+  +V+ L+  G  +     D  TPLHCAA   +V++ + L++ GA +
Sbjct: 239 GITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPI 298

Query: 896 FAMT 899
            A T
Sbjct: 299 QAKT 302



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 31/103 (30%), Positives = 45/103 (43%)

Query: 791 ERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTE 850
           ER AH      N L  L  +      D+V+ ++     P  P   G T LH A      E
Sbjct: 557 ERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVE 616

Query: 851 IVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 893
           + + L+Q+G + NA    G TPLH AA   + ++   L+   A
Sbjct: 617 VARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQA 659



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 25/65 (38%), Positives = 33/65 (50%)

Query: 835 EGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAA 894
           +G+T LH A   GH E+V  L+    N N  +  G TPLH  A   +V V   L++ G  
Sbjct: 634 QGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVM 693

Query: 895 VFAMT 899
           V A T
Sbjct: 694 VDATT 698



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 26/62 (41%), Positives = 34/62 (54%)

Query: 838 TALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFA 897
           T LH A   GHT +VK L++   N N A + G TPLH AA   +V+    L+E  A+   
Sbjct: 472 TPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQAC 531

Query: 898 MT 899
           MT
Sbjct: 532 MT 533



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 24/82 (29%), Positives = 40/82 (48%)

Query: 813 EGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTP 872
           EG  + V  ++ +    +    +G T LH A   G   + + L++   + NAA  +G TP
Sbjct: 513 EGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTP 572

Query: 873 LHCAASCNNVQVCKFLVESGAA 894
           LH A   NN+ + K L+  G +
Sbjct: 573 LHVAVHHNNLDIVKLLLPRGGS 594



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 20/58 (34%), Positives = 33/58 (56%)

Query: 836 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 893
           G++ +H A    H + V+ L+Q+   ++    D  TPLH AA C + +V K L++ GA
Sbjct: 305 GLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGA 362



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 26/80 (32%), Positives = 40/80 (50%)

Query: 814 GEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPL 873
           G  ++V+ ++    +P+L    G T LH A   GH E V  L++   +       G+TPL
Sbjct: 481 GHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPL 540

Query: 874 HCAASCNNVQVCKFLVESGA 893
           H AA    V+V + L+E  A
Sbjct: 541 HVAAKYGKVRVAELLLERDA 560



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 32/102 (31%), Positives = 47/102 (46%), Gaps = 9/102 (8%)

Query: 793 IAHGM------RVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCA 846
           I HG+      R+ + PL +   +S  G   LV+ ++    D +     G + LH A   
Sbjct: 688 IKHGVMVDATTRMGYTPLHV---ASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQ 744

Query: 847 GHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFL 888
           GHT+IV  L++ G + N   SDG TPL  A     + V   L
Sbjct: 745 GHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVL 786



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 23/59 (38%), Positives = 36/59 (61%)

Query: 836 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAA 894
           G T LH A   G+ ++VKFL+Q   +VNA    G++PLH AA   +  +   L+++GA+
Sbjct: 701 GYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGAS 759



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 28/114 (24%), Positives = 55/114 (48%), Gaps = 6/114 (5%)

Query: 826 VDDPSLPNDE---GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNV 882
           +D  + PN     G T LH A    H  +++ L++ G +++A    G TPLH A+   ++
Sbjct: 358 LDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHL 417

Query: 883 QVCKFLVESGAAVFAMTYSDMQTAADKCEEMEEGYTQCSQFLYGVQEKMGIMNK 936
            + K L++ GA   +   S+++           G+T+ +++L   + K+    K
Sbjct: 418 PIVKNLLQRGA---SPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAK 468



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 22/76 (28%), Positives = 39/76 (51%)

Query: 828 DPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKF 887
           +P + +  G T LH A    +  + + L+  G +VN    +G TPLH A+   NV + + 
Sbjct: 198 NPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRL 257

Query: 888 LVESGAAVFAMTYSDM 903
           L++ GA +   T  ++
Sbjct: 258 LLDRGAQIETKTKDEL 273



 Score = 38.9 bits (89), Expect = 0.025
 Identities = 29/95 (30%), Positives = 43/95 (45%), Gaps = 7/95 (7%)

Query: 801 FNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGV 860
           F PLA+ L    +G  ++V  +I    +        + ALH A     T     L+Q   
Sbjct: 145 FTPLAVALQ---QGHENVVAHLI----NYGTKGKVRLPALHIAARNDDTRTAAVLLQNDP 197

Query: 861 NVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAV 895
           N +     G+TPLH AA   N+ V + L+  GA+V
Sbjct: 198 NPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASV 232



 Score = 38.9 bits (89), Expect = 0.025
 Identities = 26/107 (24%), Positives = 48/107 (44%), Gaps = 3/107 (2%)

Query: 796 GMRVKFNP---LALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIV 852
           G  V F P   +  L  +S  G   +V+ ++           + +T LH A   GH  I 
Sbjct: 229 GASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRIS 288

Query: 853 KFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMT 899
           + L+  G  + A   +G +P+H AA  +++   + L++  A +  +T
Sbjct: 289 EILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDIT 335


>gi|70780357 ankyrin 1 isoform 3 [Homo sapiens]
          Length = 1880

 Score = 67.0 bits (162), Expect = 8e-11
 Identities = 35/84 (41%), Positives = 52/84 (61%)

Query: 810 SSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDG 869
           +S EG   +V  ++++         +G TALH A  AG  E+V+ LV +G NVNA    G
Sbjct: 52  ASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKG 111

Query: 870 WTPLHCAASCNNVQVCKFLVESGA 893
           +TPL+ AA  N+++V KFL+E+GA
Sbjct: 112 FTPLYMAAQENHLEVVKFLLENGA 135



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 32/84 (38%), Positives = 47/84 (55%)

Query: 810 SSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDG 869
           +S  G   +V+ ++     P++ N +  T LH A  AGHTE+ K+L+Q    VNA   D 
Sbjct: 411 ASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDD 470

Query: 870 WTPLHCAASCNNVQVCKFLVESGA 893
            TPLHCAA   +  + K L+E+ A
Sbjct: 471 QTPLHCAARIGHTNMVKLLLENNA 494



 Score = 60.5 bits (145), Expect = 8e-09
 Identities = 34/100 (34%), Positives = 55/100 (55%), Gaps = 3/100 (3%)

Query: 813 EGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTP 872
           EG  ++V  ++ +  + +L N  G+T LH     GH  +   L++ GV V+A    G+TP
Sbjct: 645 EGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTP 704

Query: 873 LHCAASCNNVQVCKFLVESGAAVFAMT---YSDMQTAADK 909
           LH A+   N+++ KFL++  A V A T   YS +  AA +
Sbjct: 705 LHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQ 744



 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 29/79 (36%), Positives = 48/79 (60%), Gaps = 3/79 (3%)

Query: 825 EVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQV 884
           E+DD +L +   +T LH A   GH  + K L+  G   N+   +G+TPLH A   N+V+V
Sbjct: 330 EIDDITLDH---LTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRV 386

Query: 885 CKFLVESGAAVFAMTYSDM 903
            + L+++GA++ A+T S +
Sbjct: 387 MELLLKTGASIDAVTESGL 405



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 26/83 (31%), Positives = 45/83 (54%)

Query: 810 SSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDG 869
           ++L G+ ++V+ ++    + +  + +G T L+ A    H E+VKFL++ G N N A  DG
Sbjct: 85  AALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDG 144

Query: 870 WTPLHCAASCNNVQVCKFLVESG 892
           +TPL  A    +  V   L+  G
Sbjct: 145 FTPLAVALQQGHENVVAHLINYG 167



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 27/69 (39%), Positives = 39/69 (56%)

Query: 834 DEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 893
           + G+T LH A   GH  IVK L+Q G + N ++    TPLH AA   + +V K+L+++ A
Sbjct: 402 ESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKA 461

Query: 894 AVFAMTYSD 902
            V A    D
Sbjct: 462 KVNAKAKDD 470



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 35/119 (29%), Positives = 57/119 (47%), Gaps = 4/119 (3%)

Query: 819 VQRIIYEVD-DPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAA 877
           V  ++ E D  P+     G+T LH AV   + +IVK L+  G + ++   +G+TPLH AA
Sbjct: 551 VAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAA 610

Query: 878 SCNNVQVCKFLVESGAAVFAMTYSDMQTAADKCEEMEEGYTQCSQFLYGVQEKMGIMNK 936
             N V+V + L++ G +  A     +Q         +EG+ +    L   Q    + NK
Sbjct: 611 KQNQVEVARSLLQYGGSANA---ESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNK 666



 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 24/64 (37%), Positives = 36/64 (56%)

Query: 836 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAV 895
           GIT LH A   G+  +V+ L+  G  +     D  TPLHCAA   +V++ + L++ GA +
Sbjct: 239 GITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPI 298

Query: 896 FAMT 899
            A T
Sbjct: 299 QAKT 302



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 31/103 (30%), Positives = 45/103 (43%)

Query: 791 ERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTE 850
           ER AH      N L  L  +      D+V+ ++     P  P   G T LH A      E
Sbjct: 557 ERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVE 616

Query: 851 IVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 893
           + + L+Q+G + NA    G TPLH AA   + ++   L+   A
Sbjct: 617 VARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQA 659



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 25/65 (38%), Positives = 33/65 (50%)

Query: 835 EGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAA 894
           +G+T LH A   GH E+V  L+    N N  +  G TPLH  A   +V V   L++ G  
Sbjct: 634 QGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVM 693

Query: 895 VFAMT 899
           V A T
Sbjct: 694 VDATT 698



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 26/62 (41%), Positives = 34/62 (54%)

Query: 838 TALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFA 897
           T LH A   GHT +VK L++   N N A + G TPLH AA   +V+    L+E  A+   
Sbjct: 472 TPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQAC 531

Query: 898 MT 899
           MT
Sbjct: 532 MT 533



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 24/82 (29%), Positives = 40/82 (48%)

Query: 813 EGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTP 872
           EG  + V  ++ +    +    +G T LH A   G   + + L++   + NAA  +G TP
Sbjct: 513 EGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTP 572

Query: 873 LHCAASCNNVQVCKFLVESGAA 894
           LH A   NN+ + K L+  G +
Sbjct: 573 LHVAVHHNNLDIVKLLLPRGGS 594



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 20/58 (34%), Positives = 33/58 (56%)

Query: 836 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 893
           G++ +H A    H + V+ L+Q+   ++    D  TPLH AA C + +V K L++ GA
Sbjct: 305 GLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGA 362



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 26/80 (32%), Positives = 40/80 (50%)

Query: 814 GEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPL 873
           G  ++V+ ++    +P+L    G T LH A   GH E V  L++   +       G+TPL
Sbjct: 481 GHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPL 540

Query: 874 HCAASCNNVQVCKFLVESGA 893
           H AA    V+V + L+E  A
Sbjct: 541 HVAAKYGKVRVAELLLERDA 560



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 32/102 (31%), Positives = 47/102 (46%), Gaps = 9/102 (8%)

Query: 793 IAHGM------RVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCA 846
           I HG+      R+ + PL +   +S  G   LV+ ++    D +     G + LH A   
Sbjct: 688 IKHGVMVDATTRMGYTPLHV---ASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQ 744

Query: 847 GHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFL 888
           GHT+IV  L++ G + N   SDG TPL  A     + V   L
Sbjct: 745 GHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVL 786



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 23/59 (38%), Positives = 36/59 (61%)

Query: 836 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAA 894
           G T LH A   G+ ++VKFL+Q   +VNA    G++PLH AA   +  +   L+++GA+
Sbjct: 701 GYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGAS 759



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 28/114 (24%), Positives = 55/114 (48%), Gaps = 6/114 (5%)

Query: 826 VDDPSLPNDE---GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNV 882
           +D  + PN     G T LH A    H  +++ L++ G +++A    G TPLH A+   ++
Sbjct: 358 LDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHL 417

Query: 883 QVCKFLVESGAAVFAMTYSDMQTAADKCEEMEEGYTQCSQFLYGVQEKMGIMNK 936
            + K L++ GA   +   S+++           G+T+ +++L   + K+    K
Sbjct: 418 PIVKNLLQRGA---SPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAK 468



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 22/76 (28%), Positives = 39/76 (51%)

Query: 828 DPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKF 887
           +P + +  G T LH A    +  + + L+  G +VN    +G TPLH A+   NV + + 
Sbjct: 198 NPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRL 257

Query: 888 LVESGAAVFAMTYSDM 903
           L++ GA +   T  ++
Sbjct: 258 LLDRGAQIETKTKDEL 273



 Score = 38.9 bits (89), Expect = 0.025
 Identities = 29/95 (30%), Positives = 43/95 (45%), Gaps = 7/95 (7%)

Query: 801 FNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGV 860
           F PLA+ L    +G  ++V  +I    +        + ALH A     T     L+Q   
Sbjct: 145 FTPLAVALQ---QGHENVVAHLI----NYGTKGKVRLPALHIAARNDDTRTAAVLLQNDP 197

Query: 861 NVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAV 895
           N +     G+TPLH AA   N+ V + L+  GA+V
Sbjct: 198 NPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASV 232



 Score = 38.9 bits (89), Expect = 0.025
 Identities = 26/107 (24%), Positives = 48/107 (44%), Gaps = 3/107 (2%)

Query: 796 GMRVKFNP---LALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIV 852
           G  V F P   +  L  +S  G   +V+ ++           + +T LH A   GH  I 
Sbjct: 229 GASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRIS 288

Query: 853 KFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMT 899
           + L+  G  + A   +G +P+H AA  +++   + L++  A +  +T
Sbjct: 289 EILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDIT 335


>gi|70780355 ankyrin 1 isoform 2 [Homo sapiens]
          Length = 1719

 Score = 67.0 bits (162), Expect = 8e-11
 Identities = 35/84 (41%), Positives = 52/84 (61%)

Query: 810 SSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDG 869
           +S EG   +V  ++++         +G TALH A  AG  E+V+ LV +G NVNA    G
Sbjct: 52  ASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKG 111

Query: 870 WTPLHCAASCNNVQVCKFLVESGA 893
           +TPL+ AA  N+++V KFL+E+GA
Sbjct: 112 FTPLYMAAQENHLEVVKFLLENGA 135



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 32/84 (38%), Positives = 47/84 (55%)

Query: 810 SSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDG 869
           +S  G   +V+ ++     P++ N +  T LH A  AGHTE+ K+L+Q    VNA   D 
Sbjct: 411 ASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDD 470

Query: 870 WTPLHCAASCNNVQVCKFLVESGA 893
            TPLHCAA   +  + K L+E+ A
Sbjct: 471 QTPLHCAARIGHTNMVKLLLENNA 494



 Score = 60.5 bits (145), Expect = 8e-09
 Identities = 34/100 (34%), Positives = 55/100 (55%), Gaps = 3/100 (3%)

Query: 813 EGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTP 872
           EG  ++V  ++ +  + +L N  G+T LH     GH  +   L++ GV V+A    G+TP
Sbjct: 645 EGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTP 704

Query: 873 LHCAASCNNVQVCKFLVESGAAVFAMT---YSDMQTAADK 909
           LH A+   N+++ KFL++  A V A T   YS +  AA +
Sbjct: 705 LHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQ 744



 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 29/79 (36%), Positives = 48/79 (60%), Gaps = 3/79 (3%)

Query: 825 EVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQV 884
           E+DD +L +   +T LH A   GH  + K L+  G   N+   +G+TPLH A   N+V+V
Sbjct: 330 EIDDITLDH---LTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRV 386

Query: 885 CKFLVESGAAVFAMTYSDM 903
            + L+++GA++ A+T S +
Sbjct: 387 MELLLKTGASIDAVTESGL 405



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 26/83 (31%), Positives = 45/83 (54%)

Query: 810 SSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDG 869
           ++L G+ ++V+ ++    + +  + +G T L+ A    H E+VKFL++ G N N A  DG
Sbjct: 85  AALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDG 144

Query: 870 WTPLHCAASCNNVQVCKFLVESG 892
           +TPL  A    +  V   L+  G
Sbjct: 145 FTPLAVALQQGHENVVAHLINYG 167



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 27/69 (39%), Positives = 39/69 (56%)

Query: 834 DEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 893
           + G+T LH A   GH  IVK L+Q G + N ++    TPLH AA   + +V K+L+++ A
Sbjct: 402 ESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKA 461

Query: 894 AVFAMTYSD 902
            V A    D
Sbjct: 462 KVNAKAKDD 470



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 35/119 (29%), Positives = 57/119 (47%), Gaps = 4/119 (3%)

Query: 819 VQRIIYEVD-DPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAA 877
           V  ++ E D  P+     G+T LH AV   + +IVK L+  G + ++   +G+TPLH AA
Sbjct: 551 VAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAA 610

Query: 878 SCNNVQVCKFLVESGAAVFAMTYSDMQTAADKCEEMEEGYTQCSQFLYGVQEKMGIMNK 936
             N V+V + L++ G +  A     +Q         +EG+ +    L   Q    + NK
Sbjct: 611 KQNQVEVARSLLQYGGSANA---ESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNK 666



 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 24/64 (37%), Positives = 36/64 (56%)

Query: 836 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAV 895
           GIT LH A   G+  +V+ L+  G  +     D  TPLHCAA   +V++ + L++ GA +
Sbjct: 239 GITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPI 298

Query: 896 FAMT 899
            A T
Sbjct: 299 QAKT 302



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 31/103 (30%), Positives = 45/103 (43%)

Query: 791 ERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTE 850
           ER AH      N L  L  +      D+V+ ++     P  P   G T LH A      E
Sbjct: 557 ERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVE 616

Query: 851 IVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 893
           + + L+Q+G + NA    G TPLH AA   + ++   L+   A
Sbjct: 617 VARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQA 659



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 25/65 (38%), Positives = 33/65 (50%)

Query: 835 EGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAA 894
           +G+T LH A   GH E+V  L+    N N  +  G TPLH  A   +V V   L++ G  
Sbjct: 634 QGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVM 693

Query: 895 VFAMT 899
           V A T
Sbjct: 694 VDATT 698



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 26/62 (41%), Positives = 34/62 (54%)

Query: 838 TALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFA 897
           T LH A   GHT +VK L++   N N A + G TPLH AA   +V+    L+E  A+   
Sbjct: 472 TPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQAC 531

Query: 898 MT 899
           MT
Sbjct: 532 MT 533



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 24/82 (29%), Positives = 40/82 (48%)

Query: 813 EGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTP 872
           EG  + V  ++ +    +    +G T LH A   G   + + L++   + NAA  +G TP
Sbjct: 513 EGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTP 572

Query: 873 LHCAASCNNVQVCKFLVESGAA 894
           LH A   NN+ + K L+  G +
Sbjct: 573 LHVAVHHNNLDIVKLLLPRGGS 594



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 20/58 (34%), Positives = 33/58 (56%)

Query: 836 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 893
           G++ +H A    H + V+ L+Q+   ++    D  TPLH AA C + +V K L++ GA
Sbjct: 305 GLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGA 362



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 26/80 (32%), Positives = 40/80 (50%)

Query: 814 GEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPL 873
           G  ++V+ ++    +P+L    G T LH A   GH E V  L++   +       G+TPL
Sbjct: 481 GHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPL 540

Query: 874 HCAASCNNVQVCKFLVESGA 893
           H AA    V+V + L+E  A
Sbjct: 541 HVAAKYGKVRVAELLLERDA 560



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 32/102 (31%), Positives = 47/102 (46%), Gaps = 9/102 (8%)

Query: 793 IAHGM------RVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCA 846
           I HG+      R+ + PL +   +S  G   LV+ ++    D +     G + LH A   
Sbjct: 688 IKHGVMVDATTRMGYTPLHV---ASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQ 744

Query: 847 GHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFL 888
           GHT+IV  L++ G + N   SDG TPL  A     + V   L
Sbjct: 745 GHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVL 786



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 23/59 (38%), Positives = 36/59 (61%)

Query: 836 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAA 894
           G T LH A   G+ ++VKFL+Q   +VNA    G++PLH AA   +  +   L+++GA+
Sbjct: 701 GYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGAS 759



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 28/114 (24%), Positives = 55/114 (48%), Gaps = 6/114 (5%)

Query: 826 VDDPSLPNDE---GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNV 882
           +D  + PN     G T LH A    H  +++ L++ G +++A    G TPLH A+   ++
Sbjct: 358 LDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHL 417

Query: 883 QVCKFLVESGAAVFAMTYSDMQTAADKCEEMEEGYTQCSQFLYGVQEKMGIMNK 936
            + K L++ GA   +   S+++           G+T+ +++L   + K+    K
Sbjct: 418 PIVKNLLQRGA---SPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAK 468



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 22/76 (28%), Positives = 39/76 (51%)

Query: 828 DPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKF 887
           +P + +  G T LH A    +  + + L+  G +VN    +G TPLH A+   NV + + 
Sbjct: 198 NPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRL 257

Query: 888 LVESGAAVFAMTYSDM 903
           L++ GA +   T  ++
Sbjct: 258 LLDRGAQIETKTKDEL 273



 Score = 38.9 bits (89), Expect = 0.025
 Identities = 29/95 (30%), Positives = 43/95 (45%), Gaps = 7/95 (7%)

Query: 801 FNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGV 860
           F PLA+ L    +G  ++V  +I    +        + ALH A     T     L+Q   
Sbjct: 145 FTPLAVALQ---QGHENVVAHLI----NYGTKGKVRLPALHIAARNDDTRTAAVLLQNDP 197

Query: 861 NVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAV 895
           N +     G+TPLH AA   N+ V + L+  GA+V
Sbjct: 198 NPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASV 232



 Score = 38.9 bits (89), Expect = 0.025
 Identities = 26/107 (24%), Positives = 48/107 (44%), Gaps = 3/107 (2%)

Query: 796 GMRVKFNP---LALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIV 852
           G  V F P   +  L  +S  G   +V+ ++           + +T LH A   GH  I 
Sbjct: 229 GASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRIS 288

Query: 853 KFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMT 899
           + L+  G  + A   +G +P+H AA  +++   + L++  A +  +T
Sbjct: 289 EILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDIT 335


>gi|70780353 ankyrin 1 isoform 4 [Homo sapiens]
          Length = 1856

 Score = 67.0 bits (162), Expect = 8e-11
 Identities = 35/84 (41%), Positives = 52/84 (61%)

Query: 810 SSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDG 869
           +S EG   +V  ++++         +G TALH A  AG  E+V+ LV +G NVNA    G
Sbjct: 52  ASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKG 111

Query: 870 WTPLHCAASCNNVQVCKFLVESGA 893
           +TPL+ AA  N+++V KFL+E+GA
Sbjct: 112 FTPLYMAAQENHLEVVKFLLENGA 135



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 32/84 (38%), Positives = 47/84 (55%)

Query: 810 SSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDG 869
           +S  G   +V+ ++     P++ N +  T LH A  AGHTE+ K+L+Q    VNA   D 
Sbjct: 411 ASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDD 470

Query: 870 WTPLHCAASCNNVQVCKFLVESGA 893
            TPLHCAA   +  + K L+E+ A
Sbjct: 471 QTPLHCAARIGHTNMVKLLLENNA 494



 Score = 60.5 bits (145), Expect = 8e-09
 Identities = 34/100 (34%), Positives = 55/100 (55%), Gaps = 3/100 (3%)

Query: 813 EGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTP 872
           EG  ++V  ++ +  + +L N  G+T LH     GH  +   L++ GV V+A    G+TP
Sbjct: 645 EGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTP 704

Query: 873 LHCAASCNNVQVCKFLVESGAAVFAMT---YSDMQTAADK 909
           LH A+   N+++ KFL++  A V A T   YS +  AA +
Sbjct: 705 LHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQ 744



 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 29/79 (36%), Positives = 48/79 (60%), Gaps = 3/79 (3%)

Query: 825 EVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQV 884
           E+DD +L +   +T LH A   GH  + K L+  G   N+   +G+TPLH A   N+V+V
Sbjct: 330 EIDDITLDH---LTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRV 386

Query: 885 CKFLVESGAAVFAMTYSDM 903
            + L+++GA++ A+T S +
Sbjct: 387 MELLLKTGASIDAVTESGL 405



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 26/83 (31%), Positives = 45/83 (54%)

Query: 810 SSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDG 869
           ++L G+ ++V+ ++    + +  + +G T L+ A    H E+VKFL++ G N N A  DG
Sbjct: 85  AALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDG 144

Query: 870 WTPLHCAASCNNVQVCKFLVESG 892
           +TPL  A    +  V   L+  G
Sbjct: 145 FTPLAVALQQGHENVVAHLINYG 167



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 27/69 (39%), Positives = 39/69 (56%)

Query: 834 DEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 893
           + G+T LH A   GH  IVK L+Q G + N ++    TPLH AA   + +V K+L+++ A
Sbjct: 402 ESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKA 461

Query: 894 AVFAMTYSD 902
            V A    D
Sbjct: 462 KVNAKAKDD 470



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 35/119 (29%), Positives = 57/119 (47%), Gaps = 4/119 (3%)

Query: 819 VQRIIYEVD-DPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAA 877
           V  ++ E D  P+     G+T LH AV   + +IVK L+  G + ++   +G+TPLH AA
Sbjct: 551 VAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAA 610

Query: 878 SCNNVQVCKFLVESGAAVFAMTYSDMQTAADKCEEMEEGYTQCSQFLYGVQEKMGIMNK 936
             N V+V + L++ G +  A     +Q         +EG+ +    L   Q    + NK
Sbjct: 611 KQNQVEVARSLLQYGGSANA---ESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNK 666



 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 24/64 (37%), Positives = 36/64 (56%)

Query: 836 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAV 895
           GIT LH A   G+  +V+ L+  G  +     D  TPLHCAA   +V++ + L++ GA +
Sbjct: 239 GITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPI 298

Query: 896 FAMT 899
            A T
Sbjct: 299 QAKT 302



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 31/103 (30%), Positives = 45/103 (43%)

Query: 791 ERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTE 850
           ER AH      N L  L  +      D+V+ ++     P  P   G T LH A      E
Sbjct: 557 ERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVE 616

Query: 851 IVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 893
           + + L+Q+G + NA    G TPLH AA   + ++   L+   A
Sbjct: 617 VARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSKQA 659



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 25/65 (38%), Positives = 33/65 (50%)

Query: 835 EGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAA 894
           +G+T LH A   GH E+V  L+    N N  +  G TPLH  A   +V V   L++ G  
Sbjct: 634 QGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVM 693

Query: 895 VFAMT 899
           V A T
Sbjct: 694 VDATT 698



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 26/62 (41%), Positives = 34/62 (54%)

Query: 838 TALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFA 897
           T LH A   GHT +VK L++   N N A + G TPLH AA   +V+    L+E  A+   
Sbjct: 472 TPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQAC 531

Query: 898 MT 899
           MT
Sbjct: 532 MT 533



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 24/82 (29%), Positives = 40/82 (48%)

Query: 813 EGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTP 872
           EG  + V  ++ +    +    +G T LH A   G   + + L++   + NAA  +G TP
Sbjct: 513 EGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTP 572

Query: 873 LHCAASCNNVQVCKFLVESGAA 894
           LH A   NN+ + K L+  G +
Sbjct: 573 LHVAVHHNNLDIVKLLLPRGGS 594



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 20/58 (34%), Positives = 33/58 (56%)

Query: 836 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 893
           G++ +H A    H + V+ L+Q+   ++    D  TPLH AA C + +V K L++ GA
Sbjct: 305 GLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGA 362



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 26/80 (32%), Positives = 40/80 (50%)

Query: 814 GEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPL 873
           G  ++V+ ++    +P+L    G T LH A   GH E V  L++   +       G+TPL
Sbjct: 481 GHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPL 540

Query: 874 HCAASCNNVQVCKFLVESGA 893
           H AA    V+V + L+E  A
Sbjct: 541 HVAAKYGKVRVAELLLERDA 560



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 32/102 (31%), Positives = 47/102 (46%), Gaps = 9/102 (8%)

Query: 793 IAHGM------RVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCA 846
           I HG+      R+ + PL +   +S  G   LV+ ++    D +     G + LH A   
Sbjct: 688 IKHGVMVDATTRMGYTPLHV---ASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQ 744

Query: 847 GHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFL 888
           GHT+IV  L++ G + N   SDG TPL  A     + V   L
Sbjct: 745 GHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVL 786



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 23/59 (38%), Positives = 36/59 (61%)

Query: 836 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAA 894
           G T LH A   G+ ++VKFL+Q   +VNA    G++PLH AA   +  +   L+++GA+
Sbjct: 701 GYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGAS 759



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 28/114 (24%), Positives = 55/114 (48%), Gaps = 6/114 (5%)

Query: 826 VDDPSLPNDE---GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNV 882
           +D  + PN     G T LH A    H  +++ L++ G +++A    G TPLH A+   ++
Sbjct: 358 LDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHL 417

Query: 883 QVCKFLVESGAAVFAMTYSDMQTAADKCEEMEEGYTQCSQFLYGVQEKMGIMNK 936
            + K L++ GA   +   S+++           G+T+ +++L   + K+    K
Sbjct: 418 PIVKNLLQRGA---SPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAK 468



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 22/76 (28%), Positives = 39/76 (51%)

Query: 828 DPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKF 887
           +P + +  G T LH A    +  + + L+  G +VN    +G TPLH A+   NV + + 
Sbjct: 198 NPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRL 257

Query: 888 LVESGAAVFAMTYSDM 903
           L++ GA +   T  ++
Sbjct: 258 LLDRGAQIETKTKDEL 273



 Score = 38.9 bits (89), Expect = 0.025
 Identities = 29/95 (30%), Positives = 43/95 (45%), Gaps = 7/95 (7%)

Query: 801 FNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGV 860
           F PLA+ L    +G  ++V  +I    +        + ALH A     T     L+Q   
Sbjct: 145 FTPLAVALQ---QGHENVVAHLI----NYGTKGKVRLPALHIAARNDDTRTAAVLLQNDP 197

Query: 861 NVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAV 895
           N +     G+TPLH AA   N+ V + L+  GA+V
Sbjct: 198 NPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASV 232



 Score = 38.9 bits (89), Expect = 0.025
 Identities = 26/107 (24%), Positives = 48/107 (44%), Gaps = 3/107 (2%)

Query: 796 GMRVKFNP---LALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIV 852
           G  V F P   +  L  +S  G   +V+ ++           + +T LH A   GH  I 
Sbjct: 229 GASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRIS 288

Query: 853 KFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMT 899
           + L+  G  + A   +G +P+H AA  +++   + L++  A +  +T
Sbjct: 289 EILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDIT 335


>gi|219842214 protein phosphatase 1, regulatory (inhibitor) subunit
           12A isoform b [Homo sapiens]
          Length = 943

 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 36/84 (42%), Positives = 47/84 (55%), Gaps = 1/84 (1%)

Query: 836 GITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAV 895
           G TALH A   G+TE++K L+Q G +VN  D DGWTPLH AA     + C+ LV++    
Sbjct: 112 GGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDN-LCD 170

Query: 896 FAMTYSDMQTAADKCEEMEEGYTQ 919
             M     QTA D  +E   GY +
Sbjct: 171 MEMVNKVGQTAFDVADEDILGYLE 194



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 32/67 (47%), Positives = 43/67 (64%), Gaps = 3/67 (4%)

Query: 851 IVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMTYSDMQTAADKC 910
           +VKFLV+ G N+N  D++GW PLH AASC  + + +FL+  GA V A+  S+  T  D  
Sbjct: 1   MVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVN-SEGDTPLDIA 59

Query: 911 EE--MEE 915
           EE  MEE
Sbjct: 60  EEEAMEE 66



 Score = 40.0 bits (92), Expect = 0.011
 Identities = 19/45 (42%), Positives = 28/45 (62%)

Query: 832 PNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCA 876
           P++EG   LH A   G+ +I +FL+  G +V A +S+G TPL  A
Sbjct: 15  PDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIA 59


>gi|41350198 fetal globin inducing factor [Homo sapiens]
          Length = 239

 Score = 64.7 bits (156), Expect = 4e-10
 Identities = 37/103 (35%), Positives = 57/103 (55%), Gaps = 1/103 (0%)

Query: 798 RVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEG-ITALHNAVCAGHTEIVKFLV 856
           +++ +P  LLL ++ +     V+R++ E        DE   T LH A  +GH +IV+ L+
Sbjct: 69  KMEKDPSRLLLWAAEKNRLTTVRRLLSEKATHVNTRDEDEYTPLHRAAYSGHLDIVQELI 128

Query: 857 QFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMT 899
             G +V+A   DGWTPLH A   NN +V  FL++  A + A T
Sbjct: 129 AQGADVHAVTVDGWTPLHSACKWNNTRVASFLLQHDADINAQT 171



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 29/95 (30%), Positives = 45/95 (47%)

Query: 783 TNLRKTGSERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHN 842
           T +R+  SE+  H      +    L  ++  G  D+VQ +I +  D      +G T LH+
Sbjct: 88  TTVRRLLSEKATHVNTRDEDEYTPLHRAAYSGHLDIVQELIAQGADVHAVTVDGWTPLHS 147

Query: 843 AVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAA 877
           A    +T +  FL+Q   ++NA      TPLH AA
Sbjct: 148 ACKWNNTRVASFLLQHDADINAQTKGLLTPLHLAA 182



 Score = 39.7 bits (91), Expect = 0.014
 Identities = 29/119 (24%), Positives = 49/119 (41%), Gaps = 3/119 (2%)

Query: 824 YEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQ 883
           Y + +  +  D     L  A     T + + L +   +VN  D D +TPLH AA   ++ 
Sbjct: 63  YRLQEKKMEKDPSRLLLWAAEKNRLTTVRRLLSEKATHVNTRDEDEYTPLHRAAYSGHLD 122

Query: 884 VCKFLVESGAAVFAMTYSDMQTAADKCEEMEEGYTQCSQFLYGVQEKMGIMNKGVIYAL 942
           + + L+  GA V A+T          C   +   T+ + FL      +    KG++  L
Sbjct: 123 IVQELIAQGADVHAVTVDGWTPLHSAC---KWNNTRVASFLLQHDADINAQTKGLLTPL 178


>gi|221139761 zinc finger protein 853 [Homo sapiens]
          Length = 659

 Score = 63.5 bits (153), Expect = 9e-10
 Identities = 56/212 (26%), Positives = 102/212 (48%), Gaps = 45/212 (21%)

Query: 14  RQQQQIEAQQQLLATKEQR------------LKFLKQQDQRQQQQVAEQEKLKRLKEIAE 61
           +QQ Q + QQQL   ++++            L+ + QQ Q Q QQV EQ++L++ +E  +
Sbjct: 119 QQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQ 178

Query: 62  NQEAKLKKVRALKGHVEQKRLSNGKLVEEIEQMNNLFQQKQRELVLAVSKVEELTRQLEM 121
            Q+A+           EQ+ L   + +++  Q   L QQ+Q +L     + ++L +Q E 
Sbjct: 179 TQQAQ-----------EQQVLQQQEQLQQQVQEQQLLQQQQEQL-----QQQQLLQQQEQ 222

Query: 122 LKNGRIDSHHDNQSAVAELDRLYKELQLRNKLNQEQNAKLQQQRECLNKRNSEVAVMDKR 181
           L+  +     +      +L  L ++ QL+ +L Q+Q A+LQQQ            +++++
Sbjct: 223 LQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQ------------LLEQQ 270

Query: 182 VNELRDRLWKKKAALQQKENLPVSSDGNLPQQ 213
             +L+ +L      LQQ+E L       L QQ
Sbjct: 271 QAQLQQQL-----LLQQQEQLQQQQQQQLLQQ 297



 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 62/274 (22%), Positives = 123/274 (44%), Gaps = 30/274 (10%)

Query: 7   ELQEMASRQQQQIEAQQQLLATKEQRLKFLKQQDQRQQQQVAEQEKLKRLKEIAENQE-- 64
           +LQ    ++QQ+++ QQ+ L T++ + + + QQ ++ QQQV EQ+ L++ +E  + Q+  
Sbjct: 158 QLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLL 217

Query: 65  AKLKKVRALKGHVEQKRLSNGK----LVEEIEQMNNLFQQKQREL--VLAVSKVEELTRQ 118
            + ++++  +   +Q++L   +    L ++ +    L QQ+Q +L   L   +  +L +Q
Sbjct: 218 QQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQ 277

Query: 119 LEMLKNGRIDSHHDNQSAVAELDRLYKELQLRNKLNQEQ---------------NAKLQQ 163
           L + +  ++      Q    + ++L ++      L  E+                 +L+Q
Sbjct: 278 LLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQ 337

Query: 164 QRECLNKRNSEVAVMDKRVNELRDRLWKKKAALQQKENLPVSSDGNLPQQAASAPSRVAA 223
           QR+ L +R  E+    +R  E R    K +  LQQ E         L QQ          
Sbjct: 338 QRQEL-ERQQEL----ERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLELTPVE 392

Query: 224 VGPYIQSSTMPRMPSRPELLVK--PALPDGSLVI 255
           +G   Q   +   P +PEL ++  PA   G   +
Sbjct: 393 LGAQQQEVQLELTPVQPELQLELVPAAGGGGAAV 426



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 55/265 (20%), Positives = 125/265 (47%), Gaps = 21/265 (7%)

Query: 9   QEMASRQQQQIEAQ---QQLLATKEQRLKFLKQQDQRQQQQVAEQEKLKRLKEIAENQEA 65
           ++   +QQ+Q++ Q   QQLL  ++++L+  +QQ  +QQ+Q+ +Q+  ++ +++ + Q+ 
Sbjct: 184 EQQVLQQQEQLQQQVQEQQLLQQQQEQLQ--QQQLLQQQEQLQQQQFQQQQEQLQQQQQL 241

Query: 66  KLKKVRA-LKGHV---EQKRLSNGKLVEEIEQMNNLFQQKQRELVLAVSKVEELTRQLEM 121
            L + +  L+  +   +Q +L    L ++  Q+      +Q+E +    + + L +Q E 
Sbjct: 242 LLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQ 301

Query: 122 LKNGRIDSH--HDNQSAVAELDRLYKELQLRNKLNQE-QNAKLQQQRECLNKRNSEVAVM 178
           L+  ++        +    EL+ +  +L    +L Q+ Q  + QQ+ E   ++      +
Sbjct: 302 LQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQELERQQEQRQLQLKL 361

Query: 179 DKRVNELRDRLWKKKAALQQKENLPVSSDGNLPQQAASAPSRVAAVGPYIQSSTMP---- 234
            + + +L  +L +++  L+Q+E     +   L  Q       +  V P +Q   +P    
Sbjct: 362 QEELQQLEQQLEQQQQQLEQQEVQLELTPVELGAQQQEVQLELTPVQPELQLELVPAAGG 421

Query: 235 ---RMPSRPELLVKPALPDGSLVIQ 256
               +P  P  +V    P G +V+Q
Sbjct: 422 GGAAVPGAPAAVV--VAPPGYVVVQ 444



 Score = 47.4 bits (111), Expect = 7e-05
 Identities = 46/160 (28%), Positives = 80/160 (50%), Gaps = 27/160 (16%)

Query: 5   LAELQEMASRQQQQIEAQQQLLATKEQRLKFLKQQDQRQQQQV------AEQEKLKRL-- 56
           L E Q+   +QQ  ++ Q+QL   ++Q+L   +QQ+Q QQQQ+       E+E+   L  
Sbjct: 266 LLEQQQAQLQQQLLLQQQEQLQQQQQQQL-LQQQQEQLQQQQLQPPPLEPEEEEEVELEL 324

Query: 57  -------KEIAENQEAKLKKVRALKGHVEQKRLSNGKLVEEIEQMNNLFQQKQRELVLAV 109
                  ++  E Q  +L++ + L+   EQ++L   KL EE++Q+    +Q+Q++L    
Sbjct: 325 MPVDLGSEQELEQQRQELERQQELERQQEQRQLQL-KLQEELQQLEQQLEQQQQQL---- 379

Query: 110 SKVEELTRQLEMLKNGRIDSHHDNQSAVAELDRLYKELQL 149
              E+   QLE+     ++     Q    EL  +  ELQL
Sbjct: 380 ---EQQEVQLELTP---VELGAQQQEVQLELTPVQPELQL 413



 Score = 39.7 bits (91), Expect = 0.014
 Identities = 59/254 (23%), Positives = 115/254 (45%), Gaps = 53/254 (20%)

Query: 15  QQQQIEAQQQLLATKEQRLKFLKQQDQRQQQQVAEQEKLKRLKEIAENQEAKLKKVRALK 74
           QQQQ + QQQLL  ++Q+ +  +Q   +QQ+Q+ +Q++ + L++  E             
Sbjct: 256 QQQQAQLQQQLL--EQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQE------------- 300

Query: 75  GHVEQKRLSNGKLVEEIEQMNNLFQQKQRELV-LAVSKVEELTRQLEMLKNGRIDSHHDN 133
             ++Q++L    L  E E      ++ + EL+ + +   +EL +Q + L+  +       
Sbjct: 301 -QLQQQQLQPPPLEPEEE------EEVELELMPVDLGSEQELEQQRQELERQQ------- 346

Query: 134 QSAVAELDRLYKELQLRNKLN---QEQNAKLQQQRECLNKRNSEVAVMDKRVNELRDRLW 190
                EL+R  ++ QL+ KL    Q+   +L+QQ++ L ++  ++ +    +   +  + 
Sbjct: 347 -----ELERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLELTPVELGAQQQEVQ 401

Query: 191 KKKAALQ---QKENLPVSSDGNLPQQAASAPSRVAAVGPYIQSSTMPRMPSRPELLVKPA 247
            +   +Q   Q E +P +  G      A A   VA  G  +            EL+V PA
Sbjct: 402 LELTPVQPELQLELVPAAGGGGAAVPGAPAAVVVAPPGYVVVQ----------ELMVLPA 451

Query: 248 LPDGSLVIQASEGP 261
           +   ++V  A  GP
Sbjct: 452 VAAPAVV--AIPGP 463


>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
           protein 6 [Homo sapiens]
          Length = 724

 Score = 63.5 bits (153), Expect = 9e-10
 Identities = 38/196 (19%), Positives = 103/196 (52%), Gaps = 6/196 (3%)

Query: 5   LAELQEMASRQQQQIEAQQQLLATKEQRLKFLKQQDQRQQQQVAEQEKLKRLKEIAENQE 64
           + E +E   RQ+++I  Q+++   +E+  +  +++  RQ++++ EQE++ R KE    QE
Sbjct: 493 IREQEEKMWRQEEKIHEQEKI---REEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQE 549

Query: 65  AKLKKVRALKGHVEQKRLSNGKLVEEIEQMNNLFQQKQRELVLAVSKVEELTRQLEMLKN 124
            K++K        E+K     + + E E+     ++K RE    + + EE  R+ E +  
Sbjct: 550 EKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQ 609

Query: 125 GRIDSHHDNQSAVAELDRLYKELQLRNKLNQEQNAKLQQQRECLNKRNSEVAVMDKRVNE 184
            + +   + +  + E +   +++Q + +  + Q  K+++Q + + ++  ++   ++ + E
Sbjct: 610 EQEEKMGEQEEKMCEQE---EKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQE 666

Query: 185 LRDRLWKKKAALQQKE 200
             +++W+++  + ++E
Sbjct: 667 QEEKMWEQEEKMCEQE 682



 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 36/195 (18%), Positives = 93/195 (47%), Gaps = 32/195 (16%)

Query: 7   ELQEMASRQQQQIEAQQQLLATKEQRLKFLKQQDQRQQQQVAEQE-KLKRLKEIAENQEA 65
           E +E   +Q++++  Q++ +  +E++++  +++  RQ++++ EQE K++  +E    QE 
Sbjct: 547 EQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEE 606

Query: 66  KLKKVRALKGHVEQKRLSNGKLVEEIEQMNNLFQQKQRELVLAVSKVEELTRQLEMLKNG 125
             ++     G  E+K     + ++E E+     ++K RE    + + EE  R+ E     
Sbjct: 607 MTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQE----- 661

Query: 126 RIDSHHDNQSAVAELDRLYKELQLRNKLNQEQNAKLQQQRECLNKRNSEVAVMDKRVNEL 185
                                     ++ QEQ  K+ +Q E + ++  ++   ++++   
Sbjct: 662 --------------------------EMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQ 695

Query: 186 RDRLWKKKAALQQKE 200
            +++W+++  L+Q+E
Sbjct: 696 EEKMWEQEVRLRQQE 710



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 43/208 (20%), Positives = 107/208 (51%), Gaps = 18/208 (8%)

Query: 17  QQIEAQ-QQLLATKEQRLKFLKQQDQRQQQQVAEQEKLKR-LKEIAENQEAKLKKVRALK 74
           +Q+E + + L++      KF  + +Q       +++K  R ++E+ + ++A   ++    
Sbjct: 215 KQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNT 274

Query: 75  GHVEQKRLSNGKLVEEIEQMNNLFQQKQRELVLAVSKVEELTRQLE----MLKNGRIDSH 130
              E+ +  N KL E+++    L + ++ E+ L    V+EL R+LE    +L   ++ + 
Sbjct: 275 ITDEELKEKNAKLQEKLQ----LVESEKSEIQL---NVKELKRKLERAKLLLPQQQLQAE 327

Query: 131 HDN-----QSAVAELDRLYKELQLRNKLNQEQNAKLQQQRECLNKRNSEVAVMDKRVNEL 185
            D+     QS  A+L    +E +L N+LNQ+Q  K+ +Q E + +   ++   ++++ E 
Sbjct: 328 ADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQ 387

Query: 186 RDRLWKKKAALQQKENLPVSSDGNLPQQ 213
            +++ +++  ++++E +    +  + +Q
Sbjct: 388 EEKIREQEEKMRRQEEMMWEKEEKMRRQ 415



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 35/198 (17%), Positives = 107/198 (54%), Gaps = 6/198 (3%)

Query: 5   LAELQEMASRQQQQIEAQQQLLATKEQRLKFLKQQDQRQQQQVAE-QEKLKRLKEIAENQ 63
           + E +E    Q+++I  Q++ +  +E+ +   +++ +RQ++ + E +EK++R +E+   +
Sbjct: 377 IQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEK 436

Query: 64  EAKLKKVRALKGHVEQKRLSNGKLVEEIEQMNNLFQQKQRELVLAVSKVEELTRQLEMLK 123
           E K++++   K H ++K     +  +E E++    Q+K++E    + + EE  R+ E   
Sbjct: 437 EEKIRELEE-KMHEQEKIREQEEKRQEEEKIRE--QEKRQEQEAKMWRQEEKIREQEEKI 493

Query: 124 NGRIDSHHDNQSAVAELDRLYKELQLRNKLNQ-EQNAKLQQQRECLNKRNSEVAVMDKRV 182
             + +     +  + E +++ +E + + +     Q  K+++Q E + ++  ++   ++++
Sbjct: 494 REQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEE-IWRQKEKIHEQEEKI 552

Query: 183 NELRDRLWKKKAALQQKE 200
            +  +++W+++  +  +E
Sbjct: 553 RKQEEKMWRQEEKMHDQE 570



 Score = 51.2 bits (121), Expect = 5e-06
 Identities = 40/203 (19%), Positives = 101/203 (49%), Gaps = 30/203 (14%)

Query: 7   ELQEMASRQQQQIEAQQQLLATKEQRLKFLKQQDQRQQQQVAEQEKLKRLKEIAENQEAK 66
           ELQ ++++ Q Q+E  +           + +   Q++++   ++EK++  +E  + QE K
Sbjct: 334 ELQSVSAKLQAQVEENEL----------WNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEK 383

Query: 67  LKKVRALKGHVEQKRLSNGKLVEEIEQMNNLFQQKQRELVLAVSKVEELTRQLEML--KN 124
           +++        E+ R    K+  + E M    ++ +R+  +   K E++ RQ EM+  K 
Sbjct: 384 IRE------QEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKE 437

Query: 125 GRI----DSHHDNQSAVAELDRLYKELQLR-NKLNQEQNAKLQQQRECLNKRNSEVAVMD 179
            +I    +  H+ +    + ++  +E ++R  +  QEQ AK+ +Q E       ++   +
Sbjct: 438 EKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEE-------KIREQE 490

Query: 180 KRVNELRDRLWKKKAALQQKENL 202
           +++ E  +++W+++  + ++E +
Sbjct: 491 EKIREQEEKMWRQEEKIHEQEKI 513



 Score = 40.0 bits (92), Expect = 0.011
 Identities = 25/124 (20%), Positives = 63/124 (50%), Gaps = 19/124 (15%)

Query: 5   LAELQEMASRQQQQIEAQQQLLATKEQRLKFLKQQDQRQQQQVAEQEK--------LKRL 56
           + E +EM   Q++++  Q++ +  +E++++  +++ +RQ++++ EQEK        ++  
Sbjct: 601 IREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQ 660

Query: 57  KEIAENQEAKL--------KKVRALKGHVEQKRLSNGKLVEE---IEQMNNLFQQKQREL 105
           +E+ + QE K+        ++   ++   E+ R    K+ E+   + Q     Q+ Q  L
Sbjct: 661 EEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHL 720

Query: 106 VLAV 109
             A+
Sbjct: 721 EAAI 724



 Score = 30.8 bits (68), Expect = 6.7
 Identities = 39/153 (25%), Positives = 64/153 (41%), Gaps = 33/153 (21%)

Query: 76  HVEQKRLSNGKLVEEIEQMNNLFQQKQRELVLAVSKVEELTRQLEMLKNGRIDSHHDNQS 135
           H  Q+ L   +L  ++  +  L  QK  EL +A+   +   +QLE      I   HD+  
Sbjct: 176 HQHQEALRR-ELEAQVHTIRILTCQKT-ELQMALYYSQHAVKQLEGEARDLISRLHDSWK 233

Query: 136 AVAEL--------------DRLYKELQ----------LRNKLN----QEQNAKLQQQREC 167
              EL              DR  +EL            RN +     +E+NAKLQ++ + 
Sbjct: 234 FAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQL 293

Query: 168 LNKRNSEVAVMDKRVNELRDRLWKKKAALQQKE 200
           +    SE+ +    V EL+ +L + K  L Q++
Sbjct: 294 VESEKSEIQL---NVKELKRKLERAKLLLPQQQ 323


>gi|56090539 dysferlin-interacting protein 1 [Homo sapiens]
          Length = 154

 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 36/97 (37%), Positives = 53/97 (54%), Gaps = 3/97 (3%)

Query: 799 VKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLP--NDEGITALHNAVCAGHTEIVKFLV 856
           V+F    L LD   +G+ + V R I      SL   +  G+ ALH AV +G+ E VK LV
Sbjct: 26  VRFPNDVLFLDHIRQGDLEQVGRFI-RTRKVSLATIHPSGLAALHEAVLSGNLECVKLLV 84

Query: 857 QFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGA 893
           ++G +++  D  GWTPLH A S     + ++L+  GA
Sbjct: 85  KYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGA 121



 Score = 37.0 bits (84), Expect = 0.093
 Identities = 20/69 (28%), Positives = 36/69 (52%)

Query: 804 LALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVN 863
           LA L ++ L G  + V+ ++    D    ++ G T LH A   G+ +I ++L+  G + +
Sbjct: 65  LAALHEAVLSGNLECVKLLVKYGADIHQRDEAGWTPLHIACSDGYPDIARYLISLGADRD 124

Query: 864 AADSDGWTP 872
           A + DG  P
Sbjct: 125 ATNDDGDLP 133


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.128    0.366 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,658,713
Number of Sequences: 37866
Number of extensions: 2634070
Number of successful extensions: 27284
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 642
Number of HSP's successfully gapped in prelim test: 1597
Number of HSP's that attempted gapping in prelim test: 13772
Number of HSP's gapped (non-prelim): 10290
length of query: 1005
length of database: 18,247,518
effective HSP length: 112
effective length of query: 893
effective length of database: 14,006,526
effective search space: 12507827718
effective search space used: 12507827718
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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