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Search of human proteins with 4885615
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4885615 signal transducer and activator of transcription 2
[Homo sapiens]
(851 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4885615 signal transducer and activator of transcription 2 [H... 1719 0.0
gi|6274552 signal transducer and activator of transcription 1 is... 539 e-153
gi|21536301 signal transducer and activator of transcription 1 i... 536 e-152
gi|4507255 signal transducer and activator of transcription 4 [H... 510 e-144
gi|47458820 signal transducer and activator of transcription 3 i... 493 e-139
gi|21618338 signal transducer and activator of transcription 3 i... 493 e-139
gi|21618340 signal transducer and activator of transcription 3 i... 493 e-139
gi|21618344 signal transducer and activator of transcription 5B ... 220 5e-57
gi|21618342 signal transducer and activator of transcription 5A ... 214 4e-55
gi|23397678 signal transducer and activator of transcription 6 [... 175 2e-43
gi|20336290 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 2 ... 39 0.020
gi|20336294 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 1 ... 39 0.020
gi|16418457 solute carrier family 26, member 8 isoform a [Homo s... 39 0.020
gi|20336285 solute carrier family 26, member 8 isoform b [Homo s... 39 0.020
gi|21264558 stromal membrane-associated GTPase-activating protei... 39 0.020
gi|64085252 hypothetical protein LOC145508 [Homo sapiens] 39 0.027
gi|226443002 jumonji, AT rich interactive domain 1D isoform 3 [H... 38 0.045
gi|33356560 jumonji, AT rich interactive domain 1D isoform 2 [Ho... 38 0.045
gi|226442991 jumonji, AT rich interactive domain 1D isoform 1 [H... 38 0.045
gi|32699028 V-set and immunoglobulin domain containing 1 [Homo s... 37 0.059
gi|56550043 sarcolemma associated protein [Homo sapiens] 37 0.077
gi|154354979 myosin X [Homo sapiens] 37 0.10
gi|31542634 filamin A interacting protein 1 [Homo sapiens] 37 0.10
gi|109715852 chromosome 6 open reading frame 204 isoform a [Homo... 37 0.10
gi|215820635 protein phosphatase 1, regulatory subunit 13 like [... 36 0.13
gi|63003907 protein phosphatase 1, regulatory subunit 13 like [H... 36 0.13
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens] 36 0.13
gi|156151379 suppressor of IKK epsilon isoform 1 [Homo sapiens] 36 0.13
gi|156151377 suppressor of IKK epsilon isoform 2 [Homo sapiens] 36 0.13
gi|153945736 keratin 27 [Homo sapiens] 36 0.17
>gi|4885615 signal transducer and activator of transcription 2 [Homo
sapiens]
Length = 851
Score = 1719 bits (4453), Expect = 0.0
Identities = 851/851 (100%), Positives = 851/851 (100%)
Query: 1 MAQWEMLQNLDSPFQDQLHQLYSHSLLPVDIRQYLAVWIEDQNWQEAALGSDDSKATMLF 60
MAQWEMLQNLDSPFQDQLHQLYSHSLLPVDIRQYLAVWIEDQNWQEAALGSDDSKATMLF
Sbjct: 1 MAQWEMLQNLDSPFQDQLHQLYSHSLLPVDIRQYLAVWIEDQNWQEAALGSDDSKATMLF 60
Query: 61 FHFLDQLNYECGRCSQDPESLLLQHNLRKFCRDIQPFSQDPTQLAEMIFNLLLEEKRILI 120
FHFLDQLNYECGRCSQDPESLLLQHNLRKFCRDIQPFSQDPTQLAEMIFNLLLEEKRILI
Sbjct: 61 FHFLDQLNYECGRCSQDPESLLLQHNLRKFCRDIQPFSQDPTQLAEMIFNLLLEEKRILI 120
Query: 121 QAQRAQLEQGEPVLETPVESQQHEIESRILDLRAMMEKLVKSISQLKDQQDVFCFRYKIQ 180
QAQRAQLEQGEPVLETPVESQQHEIESRILDLRAMMEKLVKSISQLKDQQDVFCFRYKIQ
Sbjct: 121 QAQRAQLEQGEPVLETPVESQQHEIESRILDLRAMMEKLVKSISQLKDQQDVFCFRYKIQ 180
Query: 181 AKGKTPSLDPHQTKEQKILQETLNELDKRRKEVLDASKALLGRLTTLIELLLPKLEEWKA 240
AKGKTPSLDPHQTKEQKILQETLNELDKRRKEVLDASKALLGRLTTLIELLLPKLEEWKA
Sbjct: 181 AKGKTPSLDPHQTKEQKILQETLNELDKRRKEVLDASKALLGRLTTLIELLLPKLEEWKA 240
Query: 241 QQQKACIRAPIDHGLEQLETWFTAGAKLLFHLRQLLKELKGLSCLVSYQDDPLTKGVDLR 300
QQQKACIRAPIDHGLEQLETWFTAGAKLLFHLRQLLKELKGLSCLVSYQDDPLTKGVDLR
Sbjct: 241 QQQKACIRAPIDHGLEQLETWFTAGAKLLFHLRQLLKELKGLSCLVSYQDDPLTKGVDLR 300
Query: 301 NAQVTELLQRLLHRAFVVETQPCMPQTPHRPLILKTGSKFTVRTRLLVRLQEGNESLTVE 360
NAQVTELLQRLLHRAFVVETQPCMPQTPHRPLILKTGSKFTVRTRLLVRLQEGNESLTVE
Sbjct: 301 NAQVTELLQRLLHRAFVVETQPCMPQTPHRPLILKTGSKFTVRTRLLVRLQEGNESLTVE 360
Query: 361 VSIDRNPPQLQGFRKFNILTSNQKTLTPEKGQSQGLIWDFGYLTLVEQRSGGSGKGSNKG 420
VSIDRNPPQLQGFRKFNILTSNQKTLTPEKGQSQGLIWDFGYLTLVEQRSGGSGKGSNKG
Sbjct: 361 VSIDRNPPQLQGFRKFNILTSNQKTLTPEKGQSQGLIWDFGYLTLVEQRSGGSGKGSNKG 420
Query: 421 PLGVTEELHIISFTVKYTYQGLKQELKTDTLPVVIISNMNQLSIAWASVLWFNLLSPNLQ 480
PLGVTEELHIISFTVKYTYQGLKQELKTDTLPVVIISNMNQLSIAWASVLWFNLLSPNLQ
Sbjct: 421 PLGVTEELHIISFTVKYTYQGLKQELKTDTLPVVIISNMNQLSIAWASVLWFNLLSPNLQ 480
Query: 481 NQQFFSNPPKAPWSLLGPALSWQFSSYVGRGLNSDQLSMLRNKLFGQNCRTEDPLLSWAD 540
NQQFFSNPPKAPWSLLGPALSWQFSSYVGRGLNSDQLSMLRNKLFGQNCRTEDPLLSWAD
Sbjct: 481 NQQFFSNPPKAPWSLLGPALSWQFSSYVGRGLNSDQLSMLRNKLFGQNCRTEDPLLSWAD 540
Query: 541 FTKRESPPGKLPFWTWLDKILELVHDHLKDLWNDGRIMGFVSRSQERRLLKKTMSGTFLL 600
FTKRESPPGKLPFWTWLDKILELVHDHLKDLWNDGRIMGFVSRSQERRLLKKTMSGTFLL
Sbjct: 541 FTKRESPPGKLPFWTWLDKILELVHDHLKDLWNDGRIMGFVSRSQERRLLKKTMSGTFLL 600
Query: 601 RFSESSEGGITCSWVEHQDDDKVLIYSVQPYTKEVLQSLPLTEIIRHYQLLTEENIPENP 660
RFSESSEGGITCSWVEHQDDDKVLIYSVQPYTKEVLQSLPLTEIIRHYQLLTEENIPENP
Sbjct: 601 RFSESSEGGITCSWVEHQDDDKVLIYSVQPYTKEVLQSLPLTEIIRHYQLLTEENIPENP 660
Query: 661 LRFLYPRIPRDEAFGCYYQEKVNLQERRKYLKHRLIVVSNRQVDELQQPLELKPEPELES 720
LRFLYPRIPRDEAFGCYYQEKVNLQERRKYLKHRLIVVSNRQVDELQQPLELKPEPELES
Sbjct: 661 LRFLYPRIPRDEAFGCYYQEKVNLQERRKYLKHRLIVVSNRQVDELQQPLELKPEPELES 720
Query: 721 LELELGLVPEPELSLDLEPLLKAGLDLGPELESVLESTLEPVIEPTLCMVSQTVPEPDQG 780
LELELGLVPEPELSLDLEPLLKAGLDLGPELESVLESTLEPVIEPTLCMVSQTVPEPDQG
Sbjct: 721 LELELGLVPEPELSLDLEPLLKAGLDLGPELESVLESTLEPVIEPTLCMVSQTVPEPDQG 780
Query: 781 PVSQPVPEPDLPCDLRHLNTEPMEIFRNCVKIEEIMPNGDPLLAGQNTVDEVYVSRPSHF 840
PVSQPVPEPDLPCDLRHLNTEPMEIFRNCVKIEEIMPNGDPLLAGQNTVDEVYVSRPSHF
Sbjct: 781 PVSQPVPEPDLPCDLRHLNTEPMEIFRNCVKIEEIMPNGDPLLAGQNTVDEVYVSRPSHF 840
Query: 841 YTDGPLMPSDF 851
YTDGPLMPSDF
Sbjct: 841 YTDGPLMPSDF 851
>gi|6274552 signal transducer and activator of transcription 1
isoform alpha [Homo sapiens]
Length = 750
Score = 539 bits (1389), Expect = e-153
Identities = 316/733 (43%), Positives = 448/733 (61%), Gaps = 27/733 (3%)
Query: 1 MAQWEMLQNLDSPFQDQLHQLYSHSLLPVDIRQYLAVWIEDQNWQEAALGSDDSKATMLF 60
M+QW LQ LDS F +Q+HQLY S P++IRQYLA W+E Q+W+ AA +D S AT+ F
Sbjct: 1 MSQWYELQQLDSKFLEQVHQLYDDSF-PMEIRQYLAQWLEKQDWEHAA--NDVSFATIRF 57
Query: 61 FHFLDQLNYECGRCSQDPESLLLQHNLRKFCRDIQP-FSQDPTQLAEMIFNLLLEEKRIL 119
L QL+ + R S + + LLQHN+RK R++Q F +DP Q++ +I++ L EE++IL
Sbjct: 58 HDLLSQLDDQYSRFSLE-NNFLLQHNIRKSKRNLQDNFQEDPIQMSMIIYSCLKEERKIL 116
Query: 120 IQAQRAQLEQGEPVLETPVESQQHEIESRILDLR---AMMEKLVKSISQLKDQQDVFCFR 176
AQR Q + T + +Q E++S++ +++ +E +KS+ L+D+ D C
Sbjct: 117 ENAQRFNQAQSGNIQSTVMLDKQKELDSKVRNVKDKVMCIEHEIKSLEDLQDEYDFKCKT 176
Query: 177 YKIQAKGKTPSLDPHQTKEQKILQETLNELDKRRKEVLDASKALLGRLTTLIE--LLLPK 234
+ + Q +EQ +L++ LD +RKEV+ LL +T L + L+ +
Sbjct: 177 LQNREHETNGVAKSDQKQEQLLLKKMYLMLDNKRKEVVHKIIELLN-VTELTQNALINDE 235
Query: 235 LEEWKAQQQKACIRAPIDHGLEQLETWFTAGAKLLFHLRQLLKELKGLSCLVSYQDDPLT 294
L EWK +QQ ACI P + L+QL+ WFT A+ L +RQ LK+L+ L +Y+ DP+T
Sbjct: 236 LVEWKRRQQSACIGGPPNACLDQLQNWFTIVAESLQQVRQQLKKLEELEQKYTYEHDPIT 295
Query: 295 KGVDLRNAQVTELLQRLLHRAFVVETQPCMPQTPHRPLILKTGSKFTVRTRLLVRLQEGN 354
K + + L Q+L+ +FVVE QPCMP P RPL+LKTG +FTV+ RLLV+LQE N
Sbjct: 296 KNKQVLWDRTFSLFQQLIQSSFVVERQPCMPTHPQRPLVLKTGVQFTVKLRLLVKLQELN 355
Query: 355 ESLTVEVSIDRNPPQ---LQGFRKFNILTSNQKTLTPEKGQSQGLIWDFGYLTLVEQRSG 411
+L V+V D++ + ++GFRKFNIL ++ K + E+ + L +F +L L EQ++
Sbjct: 356 YNLKVKVLFDKDVNERNTVKGFRKFNILGTHTKVMNMEESTNGSLAAEFRHLQLKEQKNA 415
Query: 412 GSGKGSNKGPLGVTEELHIISFTVKYTYQGLKQELKTDTLPVVIISNMNQLSIAWASVLW 471
G+ +N+GPL VTEELH +SF + GL +L+T +LPVV+ISN++QL WAS+LW
Sbjct: 416 GT--RTNEGPLIVTEELHSLSFETQLCQPGLVIDLETTSLPVVVISNVSQLPSGWASILW 473
Query: 472 FNLLSPNLQNQQFFSNPPKAPWSLLGPALSWQFSSYVGRGLNSDQLSMLRNKLFGQNCRT 531
+N+L +N FF PP A W+ L LSWQFSS RGLN DQL+ML KL G N +
Sbjct: 474 YNMLVAEPRNLSFFLTPPCARWAQLSEVLSWQFSSVTKRGLNVDQLNMLGEKLLGPNA-S 532
Query: 532 EDPLLSWADFTKRESPPGKLPFWTWLDKILELVHDHLKDLWNDGRIMGFVSRSQERRLLK 591
D L+ W F K PFW W++ ILEL+ HL LWNDG IMGF+S+ +ER LLK
Sbjct: 533 PDGLIPWTRFCKENINDKNFPFWLWIESILELIKKHLLPLWNDGCIMGFISKERERALLK 592
Query: 592 KTMSGTFLLRFSESS-EGGITCSWVEH-QDDDKVLIYSVQPYTKEVLQSLPLTEIIRHYQ 649
GTFLLRFSESS EG IT +WVE Q+ + ++V+PYTK+ L ++ +IIR+Y+
Sbjct: 593 DQQPGTFLLRFSESSREGAITFTWVERSQNGGEPDFHAVEPYTKKELSAVTFPDIIRNYK 652
Query: 650 LLTEENIPENPLRFLYPRIPRDEAFGCYYQEKVNLQERRK--------YLKHRLIVVSNR 701
++ ENIPENPL++LYP I +D AFG YY E + Y+K LI VS
Sbjct: 653 VMAAENIPENPLKYLYPNIDKDHAFGKYYSRPKEAPEPMELDGPKGTGYIKTELISVSEV 712
Query: 702 QVDELQQPLELKP 714
LQ L P
Sbjct: 713 HPSRLQTTDNLLP 725
>gi|21536301 signal transducer and activator of transcription 1
isoform beta [Homo sapiens]
Length = 712
Score = 536 bits (1382), Expect = e-152
Identities = 312/718 (43%), Positives = 444/718 (61%), Gaps = 27/718 (3%)
Query: 1 MAQWEMLQNLDSPFQDQLHQLYSHSLLPVDIRQYLAVWIEDQNWQEAALGSDDSKATMLF 60
M+QW LQ LDS F +Q+HQLY S P++IRQYLA W+E Q+W+ AA +D S AT+ F
Sbjct: 1 MSQWYELQQLDSKFLEQVHQLYDDSF-PMEIRQYLAQWLEKQDWEHAA--NDVSFATIRF 57
Query: 61 FHFLDQLNYECGRCSQDPESLLLQHNLRKFCRDIQP-FSQDPTQLAEMIFNLLLEEKRIL 119
L QL+ + R S + + LLQHN+RK R++Q F +DP Q++ +I++ L EE++IL
Sbjct: 58 HDLLSQLDDQYSRFSLE-NNFLLQHNIRKSKRNLQDNFQEDPIQMSMIIYSCLKEERKIL 116
Query: 120 IQAQRAQLEQGEPVLETPVESQQHEIESRILDLR---AMMEKLVKSISQLKDQQDVFCFR 176
AQR Q + T + +Q E++S++ +++ +E +KS+ L+D+ D C
Sbjct: 117 ENAQRFNQAQSGNIQSTVMLDKQKELDSKVRNVKDKVMCIEHEIKSLEDLQDEYDFKCKT 176
Query: 177 YKIQAKGKTPSLDPHQTKEQKILQETLNELDKRRKEVLDASKALLGRLTTLIE--LLLPK 234
+ + Q +EQ +L++ LD +RKEV+ LL +T L + L+ +
Sbjct: 177 LQNREHETNGVAKSDQKQEQLLLKKMYLMLDNKRKEVVHKIIELLN-VTELTQNALINDE 235
Query: 235 LEEWKAQQQKACIRAPIDHGLEQLETWFTAGAKLLFHLRQLLKELKGLSCLVSYQDDPLT 294
L EWK +QQ ACI P + L+QL+ WFT A+ L +RQ LK+L+ L +Y+ DP+T
Sbjct: 236 LVEWKRRQQSACIGGPPNACLDQLQNWFTIVAESLQQVRQQLKKLEELEQKYTYEHDPIT 295
Query: 295 KGVDLRNAQVTELLQRLLHRAFVVETQPCMPQTPHRPLILKTGSKFTVRTRLLVRLQEGN 354
K + + L Q+L+ +FVVE QPCMP P RPL+LKTG +FTV+ RLLV+LQE N
Sbjct: 296 KNKQVLWDRTFSLFQQLIQSSFVVERQPCMPTHPQRPLVLKTGVQFTVKLRLLVKLQELN 355
Query: 355 ESLTVEVSIDRNPPQ---LQGFRKFNILTSNQKTLTPEKGQSQGLIWDFGYLTLVEQRSG 411
+L V+V D++ + ++GFRKFNIL ++ K + E+ + L +F +L L EQ++
Sbjct: 356 YNLKVKVLFDKDVNERNTVKGFRKFNILGTHTKVMNMEESTNGSLAAEFRHLQLKEQKNA 415
Query: 412 GSGKGSNKGPLGVTEELHIISFTVKYTYQGLKQELKTDTLPVVIISNMNQLSIAWASVLW 471
G+ +N+GPL VTEELH +SF + GL +L+T +LPVV+ISN++QL WAS+LW
Sbjct: 416 GT--RTNEGPLIVTEELHSLSFETQLCQPGLVIDLETTSLPVVVISNVSQLPSGWASILW 473
Query: 472 FNLLSPNLQNQQFFSNPPKAPWSLLGPALSWQFSSYVGRGLNSDQLSMLRNKLFGQNCRT 531
+N+L +N FF PP A W+ L LSWQFSS RGLN DQL+ML KL G N +
Sbjct: 474 YNMLVAEPRNLSFFLTPPCARWAQLSEVLSWQFSSVTKRGLNVDQLNMLGEKLLGPNA-S 532
Query: 532 EDPLLSWADFTKRESPPGKLPFWTWLDKILELVHDHLKDLWNDGRIMGFVSRSQERRLLK 591
D L+ W F K PFW W++ ILEL+ HL LWNDG IMGF+S+ +ER LLK
Sbjct: 533 PDGLIPWTRFCKENINDKNFPFWLWIESILELIKKHLLPLWNDGCIMGFISKERERALLK 592
Query: 592 KTMSGTFLLRFSESS-EGGITCSWVEH-QDDDKVLIYSVQPYTKEVLQSLPLTEIIRHYQ 649
GTFLLRFSESS EG IT +WVE Q+ + ++V+PYTK+ L ++ +IIR+Y+
Sbjct: 593 DQQPGTFLLRFSESSREGAITFTWVERSQNGGEPDFHAVEPYTKKELSAVTFPDIIRNYK 652
Query: 650 LLTEENIPENPLRFLYPRIPRDEAFGCYYQEKVNLQERRK--------YLKHRLIVVS 699
++ ENIPENPL++LYP I +D AFG YY E + Y+K LI VS
Sbjct: 653 VMAAENIPENPLKYLYPNIDKDHAFGKYYSRPKEAPEPMELDGPKGTGYIKTELISVS 710
>gi|4507255 signal transducer and activator of transcription 4 [Homo
sapiens]
Length = 748
Score = 510 bits (1313), Expect = e-144
Identities = 290/685 (42%), Positives = 427/685 (62%), Gaps = 11/685 (1%)
Query: 1 MAQWEMLQNLDSPFQDQLHQLYSHSLLPVDIRQYLAVWIEDQNWQEAALGSDDSKATMLF 60
M+QW +Q L+ F +Q+ Q Y + P++IR LA WIE+Q+W+ A+ ++++ AT+L
Sbjct: 1 MSQWNQVQQLEIKFLEQVDQFYDDNF-PMEIRHLLAQWIENQDWEAAS--NNETMATILL 57
Query: 61 FHFLDQLNYECGRCSQDPESLLLQHNLRKFCRDIQ-PFSQDPTQLAEMIFNLLLEEKRIL 119
+ L QL+ + GR S++ ++LLL HNL++ + +Q F +P +A +I N L EE+RIL
Sbjct: 58 QNLLIQLDEQLGRVSKE-KNLLLIHNLKRIRKVLQGKFHGNPMHVAVVISNCLREERRIL 116
Query: 120 IQAQRAQLEQGEPVLETP-VESQQHEIESRILDLRAMMEKLVKSISQLKDQQDVFCFRYK 178
A E L++ V +Q +E ++ ++ ++ + L+D QD F +RYK
Sbjct: 117 AAANMPVQGPLEKSLQSSSVSERQRNVEHKVAAIKNSVQMTEQDTKYLEDLQDEFDYRYK 176
Query: 179 -IQAKGKTPSLDPHQTKEQKILQETLNELDKRRKEVLDASKALLGRLTTLIE-LLLPKLE 236
IQ ++ +E LQE LN LD +RKE L ++ L+ +L+ +L+
Sbjct: 177 TIQTMDQSDKNSAMVNQEVLTLQEMLNSLDFKRKEALSKMTQIIHETDLLMNTMLIEELQ 236
Query: 237 EWKAQQQKACIRAPIDHGLEQLETWFTAGAKLLFHLRQLLKELKGLSCLVSYQDDPLTKG 296
+WK +QQ ACI P+ +GL+QL+ FT A+ LF LR+ L++L+ S ++Y+ DP+
Sbjct: 237 DWKRRQQIACIGGPLHNGLDQLQNCFTLLAESLFQLRRQLEKLEEQSTKMTYEGDPIPMQ 296
Query: 297 VDLRNAQVTELLQRLLHRAFVVETQPCMPQTPHRPLILKTGSKFTVRTRLLVRLQEGNES 356
+VT L+ L +FVVE QPCMP P RPL+LKT +FTV+ RLL++L E N
Sbjct: 297 RTHMLERVTFLIYNLFKNSFVVERQPCMPTHPQRPLVLKTLIQFTVKLRLLIKLPELNYQ 356
Query: 357 LTVEVSIDRNPPQLQGFRKFNILTSNQKTLTPEKGQSQGLIWDFGYLTLVEQRSGGSGKG 416
+ V+ SID+N L R+F + +N K ++ E+ + L +F +L E +S GKG
Sbjct: 357 VKVKASIDKNVSTLSN-RRFVLCGTNVKAMSIEESSNGSLSVEFRHLQPKEMKSSAGGKG 415
Query: 417 SNKGPLGVTEELHIISFTVKYTYQGLKQELKTDTLPVVIISNMNQLSIAWASVLWFNLLS 476
N+G VTEELH I+F + GL +L+T +LPVV+ISN++QL AWAS++W+N+ +
Sbjct: 416 -NEGCHMVTEELHSITFETQICLYGLTIDLETSSLPVVMISNVSQLPNAWASIIWYNVST 474
Query: 477 PNLQNQQFFSNPPKAPWSLLGPALSWQFSSYVGRGLNSDQLSMLRNKLFGQNCRTEDPLL 536
+ QN FF+NPP A S L +SWQFSSYVGRGLNSDQL ML KL Q+ + D L
Sbjct: 475 NDSQNLVFFNNPPPATLSQLLEVMSWQFSSYVGRGLNSDQLHMLAEKLTVQSSYS-DGHL 533
Query: 537 SWADFTKRESPPGKLPFWTWLDKILELVHDHLKDLWNDGRIMGFVSRSQERRLLKKTMSG 596
+WA F K P FWTWL+ IL+L+ H+ LW DG +MGFVS+ +ER LLK M G
Sbjct: 534 TWAKFCKEHLPGKSFTFWTWLEAILDLIKKHILPLWIDGYVMGFVSKEKERLLLKDKMPG 593
Query: 597 TFLLRFSESSEGGITCSWVEHQDDDKVLIYSVQPYTKEVLQSLPLTEIIRHYQLLTEENI 656
TFLLRFSES GGIT +WV+H + +V +SV+PY K L +LP +I+R Y+++ ENI
Sbjct: 594 TFLLRFSESHLGGITFTWVDHSESGEVRFHSVEPYNKGRLSALPFADILRDYKVIMAENI 653
Query: 657 PENPLRFLYPRIPRDEAFGCYYQEK 681
PENPL++LYP IP+D+AFG +Y +
Sbjct: 654 PENPLKYLYPDIPKDKAFGKHYSSQ 678
>gi|47458820 signal transducer and activator of transcription 3
isoform 3 [Homo sapiens]
Length = 722
Score = 493 bits (1270), Expect = e-139
Identities = 279/690 (40%), Positives = 418/690 (60%), Gaps = 17/690 (2%)
Query: 1 MAQWEMLQNLDSPFQDQLHQLYSHSLLPVDIRQYLAVWIEDQNWQEAALGSDDSKATMLF 60
MAQW LQ LD+ + +QLHQLYS S P+++RQ+LA WIE Q+W AA S +S AT++F
Sbjct: 1 MAQWNQLQQLDTRYLEQLHQLYSDSF-PMELRQFLAPWIESQDWAYAA--SKESHATLVF 57
Query: 61 FHFLDQLNYECGRCSQDPESLLLQHNLRKFCRDIQP-FSQDPTQLAEMIFNLLLEEKRIL 119
+ L +++ + R Q+ ++L QHNLR+ + +Q + + P ++A ++ L EE R+L
Sbjct: 58 HNLLGEIDQQYSRFLQE-SNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLL 116
Query: 120 IQAQRAQLEQGEPVLETP--VESQQHEIESRILDLRAMMEKLVKSISQLKDQQDVFCFRY 177
A A + G+ T V +Q +E + D+R ++ L + + +++ QD F F Y
Sbjct: 117 QTAATAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNY 176
Query: 178 K-IQAKGKTPSLDPHQTK--EQKI--LQETLNELDKRRKEVLDASKALLGRLTTLIELLL 232
K ++++G L+ + QK+ L++ L LD+ R+ ++ LL + + + L
Sbjct: 177 KTLKSQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLT 236
Query: 233 PK-LEEWKAQQQKACIRAPIDHGLEQLETWFTAGAKLLFHLRQLLKELKGLSCLVSYQDD 291
+ L +WK +QQ ACI P + L++LE W T+ A+ RQ +K+L+ L VSY+ D
Sbjct: 237 DEELADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGD 296
Query: 292 PLTKGVDLRNAQVTELLQRLLHRAFVVETQPCMPQTPHRPLILKTGSKFTVRTRLLVRLQ 351
P+ + + ++ EL + L+ AFVVE QPCMP P RPL++KTG +FT + RLLV+
Sbjct: 297 PIVQHRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFP 356
Query: 352 EGNESLTVEVSIDRNPPQ---LQGFRKFNILTSNQKTLTPEKGQSQGLIWDFGYLTLVEQ 408
E N L ++V ID++ L+G RKFNIL +N K + E+ + L +F +LTL EQ
Sbjct: 357 ELNYQLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQ 416
Query: 409 RSGGSGKGSNKGPLGVTEELHIISFTVKYTYQGLKQELKTDTLPVVIISNMNQLSIAWAS 468
R G G+ + L VTEELH+I+F + +QGLK +L+T +LPVV+ISN+ Q+ AWAS
Sbjct: 417 RCGNGGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWAS 476
Query: 469 VLWFNLLSPNLQNQQFFSNPPKAPWSLLGPALSWQFSSYVGRGLNSDQLSMLRNKLFGQN 528
+LW+N+L+ N +N FF+ PP W + LSWQFSS RGL+ +QL+ L KL G
Sbjct: 477 ILWYNMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPG 536
Query: 529 CRTEDPLLSWADFTKRESPPGKLPFWTWLDKILELVHDHLKDLWNDGRIMGFVSRSQERR 588
++WA F K FW WLD I++LV ++ LWN+G IMGF+S+ +ER
Sbjct: 537 VNYSGCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERA 596
Query: 589 LLKKTMSGTFLLRFSESS-EGGITCSWVEHQDDDKVLIYSVQPYTKEVLQSLPLTEIIRH 647
+L GTFLLRFSESS EGG+T +WVE K I SV+PYTK+ L ++ EII
Sbjct: 597 ILSTKPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMG 656
Query: 648 YQLLTEENIPENPLRFLYPRIPRDEAFGCY 677
Y+++ NI +PL +LYP IP++EAFG Y
Sbjct: 657 YKIMDATNILVSPLVYLYPDIPKEEAFGKY 686
>gi|21618338 signal transducer and activator of transcription 3
isoform 2 [Homo sapiens]
Length = 769
Score = 493 bits (1270), Expect = e-139
Identities = 279/690 (40%), Positives = 418/690 (60%), Gaps = 17/690 (2%)
Query: 1 MAQWEMLQNLDSPFQDQLHQLYSHSLLPVDIRQYLAVWIEDQNWQEAALGSDDSKATMLF 60
MAQW LQ LD+ + +QLHQLYS S P+++RQ+LA WIE Q+W AA S +S AT++F
Sbjct: 1 MAQWNQLQQLDTRYLEQLHQLYSDSF-PMELRQFLAPWIESQDWAYAA--SKESHATLVF 57
Query: 61 FHFLDQLNYECGRCSQDPESLLLQHNLRKFCRDIQP-FSQDPTQLAEMIFNLLLEEKRIL 119
+ L +++ + R Q+ ++L QHNLR+ + +Q + + P ++A ++ L EE R+L
Sbjct: 58 HNLLGEIDQQYSRFLQE-SNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLL 116
Query: 120 IQAQRAQLEQGEPVLETP--VESQQHEIESRILDLRAMMEKLVKSISQLKDQQDVFCFRY 177
A A + G+ T V +Q +E + D+R ++ L + + +++ QD F F Y
Sbjct: 117 QTAATAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNY 176
Query: 178 K-IQAKGKTPSLDPHQTK--EQKI--LQETLNELDKRRKEVLDASKALLGRLTTLIELLL 232
K ++++G L+ + QK+ L++ L LD+ R+ ++ LL + + + L
Sbjct: 177 KTLKSQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLT 236
Query: 233 PK-LEEWKAQQQKACIRAPIDHGLEQLETWFTAGAKLLFHLRQLLKELKGLSCLVSYQDD 291
+ L +WK +QQ ACI P + L++LE W T+ A+ RQ +K+L+ L VSY+ D
Sbjct: 237 DEELADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGD 296
Query: 292 PLTKGVDLRNAQVTELLQRLLHRAFVVETQPCMPQTPHRPLILKTGSKFTVRTRLLVRLQ 351
P+ + + ++ EL + L+ AFVVE QPCMP P RPL++KTG +FT + RLLV+
Sbjct: 297 PIVQHRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFP 356
Query: 352 EGNESLTVEVSIDRNPPQ---LQGFRKFNILTSNQKTLTPEKGQSQGLIWDFGYLTLVEQ 408
E N L ++V ID++ L+G RKFNIL +N K + E+ + L +F +LTL EQ
Sbjct: 357 ELNYQLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQ 416
Query: 409 RSGGSGKGSNKGPLGVTEELHIISFTVKYTYQGLKQELKTDTLPVVIISNMNQLSIAWAS 468
R G G+ + L VTEELH+I+F + +QGLK +L+T +LPVV+ISN+ Q+ AWAS
Sbjct: 417 RCGNGGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWAS 476
Query: 469 VLWFNLLSPNLQNQQFFSNPPKAPWSLLGPALSWQFSSYVGRGLNSDQLSMLRNKLFGQN 528
+LW+N+L+ N +N FF+ PP W + LSWQFSS RGL+ +QL+ L KL G
Sbjct: 477 ILWYNMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPG 536
Query: 529 CRTEDPLLSWADFTKRESPPGKLPFWTWLDKILELVHDHLKDLWNDGRIMGFVSRSQERR 588
++WA F K FW WLD I++LV ++ LWN+G IMGF+S+ +ER
Sbjct: 537 VNYSGCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERA 596
Query: 589 LLKKTMSGTFLLRFSESS-EGGITCSWVEHQDDDKVLIYSVQPYTKEVLQSLPLTEIIRH 647
+L GTFLLRFSESS EGG+T +WVE K I SV+PYTK+ L ++ EII
Sbjct: 597 ILSTKPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMG 656
Query: 648 YQLLTEENIPENPLRFLYPRIPRDEAFGCY 677
Y+++ NI +PL +LYP IP++EAFG Y
Sbjct: 657 YKIMDATNILVSPLVYLYPDIPKEEAFGKY 686
>gi|21618340 signal transducer and activator of transcription 3
isoform 1 [Homo sapiens]
Length = 770
Score = 493 bits (1270), Expect = e-139
Identities = 279/690 (40%), Positives = 418/690 (60%), Gaps = 17/690 (2%)
Query: 1 MAQWEMLQNLDSPFQDQLHQLYSHSLLPVDIRQYLAVWIEDQNWQEAALGSDDSKATMLF 60
MAQW LQ LD+ + +QLHQLYS S P+++RQ+LA WIE Q+W AA S +S AT++F
Sbjct: 1 MAQWNQLQQLDTRYLEQLHQLYSDSF-PMELRQFLAPWIESQDWAYAA--SKESHATLVF 57
Query: 61 FHFLDQLNYECGRCSQDPESLLLQHNLRKFCRDIQP-FSQDPTQLAEMIFNLLLEEKRIL 119
+ L +++ + R Q+ ++L QHNLR+ + +Q + + P ++A ++ L EE R+L
Sbjct: 58 HNLLGEIDQQYSRFLQE-SNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLL 116
Query: 120 IQAQRAQLEQGEPVLETP--VESQQHEIESRILDLRAMMEKLVKSISQLKDQQDVFCFRY 177
A A + G+ T V +Q +E + D+R ++ L + + +++ QD F F Y
Sbjct: 117 QTAATAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNY 176
Query: 178 K-IQAKGKTPSLDPHQTK--EQKI--LQETLNELDKRRKEVLDASKALLGRLTTLIELLL 232
K ++++G L+ + QK+ L++ L LD+ R+ ++ LL + + + L
Sbjct: 177 KTLKSQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLT 236
Query: 233 PK-LEEWKAQQQKACIRAPIDHGLEQLETWFTAGAKLLFHLRQLLKELKGLSCLVSYQDD 291
+ L +WK +QQ ACI P + L++LE W T+ A+ RQ +K+L+ L VSY+ D
Sbjct: 237 DEELADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGD 296
Query: 292 PLTKGVDLRNAQVTELLQRLLHRAFVVETQPCMPQTPHRPLILKTGSKFTVRTRLLVRLQ 351
P+ + + ++ EL + L+ AFVVE QPCMP P RPL++KTG +FT + RLLV+
Sbjct: 297 PIVQHRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFP 356
Query: 352 EGNESLTVEVSIDRNPPQ---LQGFRKFNILTSNQKTLTPEKGQSQGLIWDFGYLTLVEQ 408
E N L ++V ID++ L+G RKFNIL +N K + E+ + L +F +LTL EQ
Sbjct: 357 ELNYQLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQ 416
Query: 409 RSGGSGKGSNKGPLGVTEELHIISFTVKYTYQGLKQELKTDTLPVVIISNMNQLSIAWAS 468
R G G+ + L VTEELH+I+F + +QGLK +L+T +LPVV+ISN+ Q+ AWAS
Sbjct: 417 RCGNGGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWAS 476
Query: 469 VLWFNLLSPNLQNQQFFSNPPKAPWSLLGPALSWQFSSYVGRGLNSDQLSMLRNKLFGQN 528
+LW+N+L+ N +N FF+ PP W + LSWQFSS RGL+ +QL+ L KL G
Sbjct: 477 ILWYNMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPG 536
Query: 529 CRTEDPLLSWADFTKRESPPGKLPFWTWLDKILELVHDHLKDLWNDGRIMGFVSRSQERR 588
++WA F K FW WLD I++LV ++ LWN+G IMGF+S+ +ER
Sbjct: 537 VNYSGCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERA 596
Query: 589 LLKKTMSGTFLLRFSESS-EGGITCSWVEHQDDDKVLIYSVQPYTKEVLQSLPLTEIIRH 647
+L GTFLLRFSESS EGG+T +WVE K I SV+PYTK+ L ++ EII
Sbjct: 597 ILSTKPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMG 656
Query: 648 YQLLTEENIPENPLRFLYPRIPRDEAFGCY 677
Y+++ NI +PL +LYP IP++EAFG Y
Sbjct: 657 YKIMDATNILVSPLVYLYPDIPKEEAFGKY 686
>gi|21618344 signal transducer and activator of transcription 5B
[Homo sapiens]
Length = 787
Score = 220 bits (560), Expect = 5e-57
Identities = 196/730 (26%), Positives = 329/730 (45%), Gaps = 99/730 (13%)
Query: 1 MAQWEMLQNLDSPFQDQLHQLYSHSLLPVDIRQYLAVWIEDQNWQEAALGS--DDSKATM 58
MA W Q L Q+ LY P+++R YL+ WIE Q W L + ++ KAT
Sbjct: 1 MAVWIQAQQLQGEALHQMQALYGQHF-PIEVRHYLSQWIESQAWDSVDLDNPQENIKATQ 59
Query: 59 LFFHFLDQLNYECGRCSQDPESLLLQHNLRKFCRDIQ-PFSQDPTQLAEMIFNLLLEEKR 117
L + +L + + LL+ L + +Q + + P +L I ++L E+R
Sbjct: 60 LLEGLVQELQKKAEH-QVGEDGFLLKIKLGHYATQLQNTYDRCPMELVRCIRHILYNEQR 118
Query: 118 ILIQAQRAQLEQGEPVLETPVESQQHEIESRILDLRAMMEKLVKSISQLKDQQDVFCFRY 177
++ +A G L + + +I +LR + + + +L+ Q+ F +Y
Sbjct: 119 LVREANNGSSPAGS--LADAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQY 176
Query: 178 ----KIQAK--------------------GKTPSLDPHQTKEQKILQETLNELDKRRKEV 213
+IQA+ K SL+ +E + LQ+ EL ++ ++
Sbjct: 177 QESLRIQAQFGPLAQLSPQERLSRETALQQKQVSLEAWLQREAQTLQQYRVELAEKHQKT 236
Query: 214 LDASKALLGRLTTLIELLLPKLEEWKAQQQKACIRAPIDHGLEQLETWFTAGAKLLFHLR 273
L LL + T+I L +L +WK +QQ A P + L+ L++W A++++ R
Sbjct: 237 LQ----LLRKQQTII--LDDELIQWKRRQQLAGNGGPPEGSLDVLQSWCEKLAEIIWQNR 290
Query: 274 QLLKELKGLSCLVSYQDDPLTKGVDLRNAQVTELLQRLLHRAFVVETQPCMPQTPHRPLI 333
Q ++ + L C P+ + + NA +T+++ L+ F++E QP P +
Sbjct: 291 QQIRRAEHL-CQQLPIPGPVEEMLAEVNATITDIISALVTSTFIIEKQP--------PQV 341
Query: 334 LKTGSKFTVRTRLLVRLQEGNESLTVEVSIDRNPPQLQGF----RKFNILTSNQKTLTPE 389
LKT +KF RLLV ++++ NPPQ++ ++ L N+ T
Sbjct: 342 LKTQTKFAATVRLLVG---------GKLNVHMNPPQVKATIISEQQAKSLLKNENTRNDY 392
Query: 390 KG------------QSQG-LIWDFGYLTLVEQRSGGSGKGSNKGPLGVTEELHIISFTVK 436
G Q+ G L F ++L + + +G VTEE I F +
Sbjct: 393 SGEILNNCCVMEYHQATGTLSAHFRNMSLKRIK-----RSDRRGAESVTEEKFTILFESQ 447
Query: 437 YTYQG--LKQELKTDTLPVVIISNMNQLSIAWASVLWFNLLSPNLQNQQFFSNPPKAPWS 494
++ G L ++KT +LPVV+I + +Q + A A+VLW N + + F+ P K W
Sbjct: 448 FSVGGNELVFQVKTLSLPVVVIVHGSQDNNATATVLWDNAFAE--PGRVPFAVPDKVLWP 505
Query: 495 LLGPALSWQFSSYV--GRGLNSDQLSMLRNKLFGQNCRTEDPL----LSWADFTKRESPP 548
L AL+ +F + V RGL + L L KLF + + +SW+ F + P
Sbjct: 506 QLCEALNMKFKAEVQSNRGLTKENLVFLAQKLFNNSSSHLEDYSGLSVSWSQFNRENLPG 565
Query: 549 GKLPFWTWLDKILELVHDHLKDLWNDGRIMGFVSRSQERRLLKKTMSGTFLLRFSESSEG 608
FW W D ++E++ HLK WNDG I+GFV++ Q LL GTFLLRFS+S G
Sbjct: 566 RNYTFWQWFDGVMEVLKKHLKPHWNDGAILGFVNKQQAHDLLINKPDGTFLLRFSDSEIG 625
Query: 609 GITCSWVEHQDDDKVLIYSVQPYTKEVLQSLPLTEIIRHYQLLTEENIPENPLRFLYPRI 668
GIT +W D + + +++ P+T L + + N L +++P
Sbjct: 626 GITIAW--KFDSQERMFWNLMPFTTRDFSIRSLADRLGDL----------NYLIYVFPDR 673
Query: 669 PRDEAFGCYY 678
P+DE + YY
Sbjct: 674 PKDEVYSKYY 683
>gi|21618342 signal transducer and activator of transcription 5A
[Homo sapiens]
Length = 794
Score = 214 bits (544), Expect = 4e-55
Identities = 192/729 (26%), Positives = 326/729 (44%), Gaps = 97/729 (13%)
Query: 1 MAQWEMLQNLDSPFQDQLHQLYSHSLLPVDIRQYLAVWIEDQNWQEAALGS--DDSKATM 58
MA W Q L Q+ LY P+++R YLA WIE Q W L + D ++AT
Sbjct: 1 MAGWIQAQQLQGDALRQMQVLYGQHF-PIEVRHYLAQWIESQPWDAIDLDNPQDRAQATQ 59
Query: 59 LFFHFLDQLNYECGRCSQDPESLLLQHNLRKFCRDIQP-FSQDPTQLAEMIFNLLLEEKR 117
L + +L + + LL+ L + +Q + + P +L I ++L E+R
Sbjct: 60 LLEGLVQELQKKAEH-QVGEDGFLLKIKLGHYATQLQKTYDRCPLELVRCIRHILYNEQR 118
Query: 118 ILIQAQRAQLEQGEPVLETPVESQQHEIESRILDLRAMMEKLVKSISQLKDQQDVFCFRY 177
++ +A G +L + + +I +LR + + + +L+ Q+ F +Y
Sbjct: 119 LVREANNCSSPAG--ILVDAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQY 176
Query: 178 ----KIQAK--------------------GKTPSLDPHQTKEQKILQETLNELDKRRKEV 213
+IQA+ K SL+ +E + LQ+ EL ++ ++
Sbjct: 177 QESLRIQAQFAQLAQLSPQERLSRETALQQKQVSLEAWLQREAQTLQQYRVELAEKHQKT 236
Query: 214 LDASKALLGRLTTLIELLLPKLEEWKAQQQKACIRAPIDHGLEQLETWFTAGAKLLFHLR 273
L LL + T+I L +L +WK +QQ A P + L+ L++W A++++ R
Sbjct: 237 LQ----LLRKQQTII--LDDELIQWKRRQQLAGNGGPPEGSLDVLQSWCEKLAEIIWQNR 290
Query: 274 QLLKELKGLSCLVSYQDDPLTKGVDLRNAQVTELLQRLLHRAFVVETQPCMPQTPHRPLI 333
Q ++ + L C P+ + + NA +T+++ L+ F++E QP P +
Sbjct: 291 QQIRRAEHL-CQQLPIPGPVEEMLAEVNATITDIISALVTSTFIIEKQP--------PQV 341
Query: 334 LKTGSKFTVRTRLLVRLQEGNESLTVEVSIDRNPPQLQGF----RKFNILTSNQKTLTPE 389
LKT +KF RLLV ++++ NPPQ++ ++ L N+ T
Sbjct: 342 LKTQTKFAATVRLLVG---------GKLNVHMNPPQVKATIISEQQAKSLLKNENT---- 388
Query: 390 KGQSQGLIWDFGYLTLVEQRSGGSG------------KGSNKGPLGVTEELHIISFTVKY 437
+ + G I + + Q +G + +G VTEE + F ++
Sbjct: 389 RNECSGEILNNCCVMEYHQATGTLSAHFRNMSLKRIKRADRRGAESVTEEKFTVLFESQF 448
Query: 438 TYQG--LKQELKTDTLPVVIISNMNQLSIAWASVLWFNLLSPNLQNQQFFSNPPKAPWSL 495
+ L ++KT +LPVV+I + +Q A A+VLW N + + F+ P K W
Sbjct: 449 SVGSNELVFQVKTLSLPVVVIVHGSQDHNATATVLWDNAFAE--PGRVPFAVPDKVLWPQ 506
Query: 496 LGPALSWQFSSYV--GRGLNSDQLSMLRNKLFGQNCRTEDPL----LSWADFTKRESPPG 549
L AL+ +F + V RGL + L L KLF + + +SW+ F + P
Sbjct: 507 LCEALNMKFKAEVQSNRGLTKENLVFLAQKLFNNSSSHLEDYSGLSVSWSQFNRENLPGW 566
Query: 550 KLPFWTWLDKILELVHDHLKDLWNDGRIMGFVSRSQERRLLKKTMSGTFLLRFSESSEGG 609
FW W D ++E++ H K WNDG I+GFV++ Q LL GTFLLRFS+S GG
Sbjct: 567 NYTFWQWFDGVMEVLKKHHKPHWNDGAILGFVNKQQAHDLLINKPDGTFLLRFSDSEIGG 626
Query: 610 ITCSWVEHQDDDKVLIYSVQPYTKEVLQSLPLTEIIRHYQLLTEENIPENPLRFLYPRIP 669
IT +W D + +++++P+T L + + L +++P P
Sbjct: 627 ITIAW--KFDSPERNLWNLKPFTTRDFSIRSLADRLGDLSYLI----------YVFPDRP 674
Query: 670 RDEAFGCYY 678
+DE F YY
Sbjct: 675 KDEVFSKYY 683
>gi|23397678 signal transducer and activator of transcription 6
[Homo sapiens]
Length = 847
Score = 175 bits (443), Expect = 2e-43
Identities = 228/900 (25%), Positives = 378/900 (42%), Gaps = 161/900 (17%)
Query: 1 MAQWEMLQNLDSPFQDQLHQLYSHSLLPVDIRQYLAVWIEDQNWQEAALGSDD---SKAT 57
M+ W ++ + +++ +LY P +R L W+E Q W E +GSD + A+
Sbjct: 1 MSLWGLVSKMPP---EKVQRLYVD--FPQHLRHLLGDWLESQPW-EFLVGSDAFCCNLAS 54
Query: 58 MLFFHFLDQLNYECGRCSQDPESLLLQH--NLRKFCRDIQPFSQDPTQLAEMIFNLLLEE 115
L + L G Q S +LQH L + +DP +L +L E
Sbjct: 55 ALLSDTVQHLQASVGE--QGEGSTILQHISTLESI------YQRDPLKLVATFRQILQGE 106
Query: 116 KRILIQAQRAQLEQGEPVLETPVESQQHEIESRILDLRAMMEKLVKSISQLKD--QQDVF 173
K+ +++ R L P +Q E++ + LR + + V I L++ Q+
Sbjct: 107 KKAVMEQFRH--------LPMPFHWKQEELKFKT-GLRRLQHR-VGEIHLLREALQKGAE 156
Query: 174 CFRYKIQAKGKTPSLDPHQTKE-QKILQETLNELDKRRKEVLDASKALLGRLTTLIELLL 232
+ + + +TP+ ++ +LQET EL+ A+KAL+ L
Sbjct: 157 AGQVSLHSLIETPANGTGPSEALAMLLQETTGELE--------AAKALV----------L 198
Query: 233 PKLEEWKAQQQKACIRAPIDHGLEQLETWFTAGAKLLFHLRQLLKELKGLSCLVSYQDDP 292
+++ WK QQQ A AP + L L+ + + L+Q + G + +P
Sbjct: 199 KRIQIWKRQQQLAGNGAPFEESLAPLQERCESLVDIYSQLQQEVGAAGG-------ELEP 251
Query: 293 LTKGVDLRNAQVTELLQRLLHRAFVVETQPCMPQTPHRPLILKTGSKFTVRTRLL----- 347
T+ ++ E+L+ L+ F+VE QP P +LKT +KF R L
Sbjct: 252 KTRAS--LTGRLDEVLRTLVTSCFLVEKQP--------PQVLKTQTKFQAGVRFLLGLRF 301
Query: 348 ---------VRLQEGNESLTVEVSIDRNPPQLQGFRKFNILTSNQKTLTPEKGQSQGLIW 398
VR E E+S+ + P G + +N P + G
Sbjct: 302 LGAPAKPPLVRADMVTEKQARELSVPQGPGA--GAESTGEIINNT---VPLENSIPGNCC 356
Query: 399 DFGYLTLVEQRSGGSGKGSNKGPLGVTEELHIISFTVKYTYQG--LKQELKTDTLPVVII 456
+ L+ ++ + KG VTEE + F+ +T L +L+ +LP+V+I
Sbjct: 357 SALFKNLLLKKIK---RCERKGTESVTEEKCAVLFSASFTLGPGKLPIQLQALSLPLVVI 413
Query: 457 SNMNQLSIAWASVLWFNLLSPNLQNQQFFSNPPKAPWSLLGPALSWQFSSYVG--RGLNS 514
+ NQ + A A++LW N S ++ F + PW + L+ +F + VG RGL
Sbjct: 414 VHGNQDNNAKATILWDNAFSE--MDRVPFVVAERVPWEKMCETLNLKFMAEVGTNRGLLP 471
Query: 515 DQLSMLRNKLFGQNCRTEDPL----LSWADFTKRESPPGKLPFWTWLDKILELVHDHLKD 570
+ L K+F N + + +SW+ F K FW W D +L+L L+
Sbjct: 472 EHFLFLAQKIFNDNSLSMEAFQHRSVSWSQFNKEILLGRGFTFWQWFDGVLDLTKRCLRS 531
Query: 571 LWNDGRIMGFVSRSQERRLLKKTMSGTFLLRFSESSEGGITCSWVEHQDDDKVLIYSVQP 630
W+D I+GF+S+ LL GTFLLRFS+S GGIT + V D I ++QP
Sbjct: 532 YWSDRLIIGFISKQYVTSLLLNEPDGTFLLRFSDSEIGGITIAHVIRGQDGSPQIENIQP 591
Query: 631 YTKEVLQSLPLTEIIRHYQLLTEENIPENPLRFLYPRIPRDEAFGCYYQEKVNLQERRKY 690
++ + L L + IR L+ LYP+ P+DEAF +Y+ + ++ R Y
Sbjct: 592 FSAKDLSIRSLGDRIRDLA----------QLKNLYPKKPKDEAFRSHYKPEQMGKDGRGY 641
Query: 691 LKHRLIVVSNRQVDELQQPLELKPEPELESLEL----ELGLVPEPELSLDLEPLLKAGL- 745
+ + + E QPL P PEL+ + +LG+ P+ +S+ L P + +
Sbjct: 642 -----VPATIKMTVERDQPL---PTPELQMPTMVPSYDLGMAPDSSMSMQLGPDMVPQVY 693
Query: 746 -----------DLGPELE-SVLESTLEPVIE--PTLCMVSQTVPEPDQGPVSQPVPEPDL 791
L PE +VL + EP ++ P+L +S P QP P+ L
Sbjct: 694 PPHSHSIPPYQGLSPEESVNVLSAFQEPHLQMPPSLGQMSL--------PFDQPHPQGLL 745
Query: 792 PCDLRHLNTEPMEIFRNCVKIEEIMPNGDPLLAGQNT-VDEVYVSRPSHFYTDGPLMPSD 850
PC + E + + DPLL T V++ +S+P + G + D
Sbjct: 746 PCQPQ----------------EHAVSSPDPLLCSDVTMVEDSCLSQPVTAFPQGTWIGED 789
>gi|20336290 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 2
[Homo sapiens]
Length = 1155
Score = 38.9 bits (89), Expect = 0.020
Identities = 40/134 (29%), Positives = 62/134 (46%), Gaps = 14/134 (10%)
Query: 673 AFGCYYQEKVNLQERRKY-LKHRLI-VVSNRQVDELQQ-PLELK-PEPELESLELELGLV 728
A C + + L +R L H + + S R++ E Q+ P ++ PEP L +E L
Sbjct: 267 ALACKKLKSLGLVDRNNEPLTHAMYNLASLRELGETQRRPCTIQVPEPILRKIETFLNHY 326
Query: 729 P------EPELSLDLEPLLKAGLDLGPELESVLESTLEPVIEPTLCMVSQTVPE--PDQG 780
P PEL L + +L G D GP + + P++E +SQ++ E +G
Sbjct: 327 PVESSWIAPELRLQSDDILPLGKDSGPLSDPITGKPYVPLLEAEEVRLSQSLLELWRRRG 386
Query: 781 PVSQPVPEPDLPCD 794
PV Q P+ LP D
Sbjct: 387 PVWQEAPQ--LPVD 398
>gi|20336294 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 1
[Homo sapiens]
Length = 1194
Score = 38.9 bits (89), Expect = 0.020
Identities = 40/134 (29%), Positives = 62/134 (46%), Gaps = 14/134 (10%)
Query: 673 AFGCYYQEKVNLQERRKY-LKHRLI-VVSNRQVDELQQ-PLELK-PEPELESLELELGLV 728
A C + + L +R L H + + S R++ E Q+ P ++ PEP L +E L
Sbjct: 306 ALACKKLKSLGLVDRNNEPLTHAMYNLASLRELGETQRRPCTIQVPEPILRKIETFLNHY 365
Query: 729 P------EPELSLDLEPLLKAGLDLGPELESVLESTLEPVIEPTLCMVSQTVPE--PDQG 780
P PEL L + +L G D GP + + P++E +SQ++ E +G
Sbjct: 366 PVESSWIAPELRLQSDDILPLGKDSGPLSDPITGKPYVPLLEAEEVRLSQSLLELWRRRG 425
Query: 781 PVSQPVPEPDLPCD 794
PV Q P+ LP D
Sbjct: 426 PVWQEAPQ--LPVD 437
>gi|16418457 solute carrier family 26, member 8 isoform a [Homo
sapiens]
Length = 970
Score = 38.9 bits (89), Expect = 0.020
Identities = 21/68 (30%), Positives = 37/68 (54%)
Query: 721 LELELGLVPEPELSLDLEPLLKAGLDLGPELESVLESTLEPVIEPTLCMVSQTVPEPDQG 780
++++ + E EL L+LE +AGL L +L+ LE +EP E ++ P+P+
Sbjct: 848 IKIQQPVEEESELDLELESEQEAGLGLDLDLDRELEPEMEPKAETETKTQTEMEPQPETE 907
Query: 781 PVSQPVPE 788
P +P P+
Sbjct: 908 PEMEPNPK 915
>gi|20336285 solute carrier family 26, member 8 isoform b [Homo
sapiens]
Length = 865
Score = 38.9 bits (89), Expect = 0.020
Identities = 21/68 (30%), Positives = 37/68 (54%)
Query: 721 LELELGLVPEPELSLDLEPLLKAGLDLGPELESVLESTLEPVIEPTLCMVSQTVPEPDQG 780
++++ + E EL L+LE +AGL L +L+ LE +EP E ++ P+P+
Sbjct: 743 IKIQQPVEEESELDLELESEQEAGLGLDLDLDRELEPEMEPKAETETKTQTEMEPQPETE 802
Query: 781 PVSQPVPE 788
P +P P+
Sbjct: 803 PEMEPNPK 810
>gi|21264558 stromal membrane-associated GTPase-activating protein 1
isoform B [Homo sapiens]
Length = 440
Score = 38.9 bits (89), Expect = 0.020
Identities = 39/159 (24%), Positives = 70/159 (44%), Gaps = 35/159 (22%)
Query: 649 QLLTEENIPENPLRFLYPRIPRDEAFGCYYQEKVNLQERRKYLKHRLIVVSNRQVDELQQ 708
+LL E N+PEN + R D+A + ++K E++KY I ++N++ ++ ++
Sbjct: 95 RLLYEANLPEN-----FRRPQTDQAVEFFIRDKY---EKKKYYDKNAIAITNKEKEKKKE 146
Query: 709 PLELKPEPELESLELELGLVPEPELSLDLEPLLKAGLDLGPELESVLESTLEPVIE---- 764
+ + EPE +P L E L K L P+ + + EP ++
Sbjct: 147 EKKREKEPE------------KPAKPLTAEKLQKKDQQLEPKKSTSPKKAAEPTVDLLGL 194
Query: 765 --PTLCMVSQ---TVPEPDQ-----GP-VSQPVPEPDLP 792
P + V+ TVP + GP +S P+P +P
Sbjct: 195 DGPAVAPVTNGNTTVPPLNDDLDIFGPMISNPLPATVMP 233
>gi|64085252 hypothetical protein LOC145508 [Homo sapiens]
Length = 1094
Score = 38.5 bits (88), Expect = 0.027
Identities = 40/174 (22%), Positives = 75/174 (43%), Gaps = 5/174 (2%)
Query: 73 RCSQDPESLLLQHNLRKFCRDIQPFSQDPTQLAEMIFNLLLEEKRILIQAQRAQLEQGEP 132
R Q+ + + H + RD+ S + +L + L R + +RA E E
Sbjct: 150 RFVQETDDMTQLHGFHQSLRDL---SSEQIRLGDDFNRELSRRSRSDAETKRALEELTEK 206
Query: 133 VLETPV-ESQQHEIESRILDLRAMMEKLVKSISQLKDQQDVFCFRYKIQAKGKTPSLDPH 191
+ E E +E R+ +L M + + + +DQ + + + K + D H
Sbjct: 207 LNEAQKQEVVSDRVERRLQELEREMRTERELVERRQDQLGLMSLQLQEALKKQEAKADEH 266
Query: 192 QTKEQKILQETLNELDKRRKEVLDASKALLGRLTTLIELLLPKLEEWKAQQQKA 245
+ + L++T E ++ +E L+ S+ LL + E LL ++EE + Q KA
Sbjct: 267 EGAIKNKLRQTETEKNQLEQE-LELSRRLLNQSEGSRETLLHQVEELRTQLTKA 319
Score = 32.0 bits (71), Expect = 2.5
Identities = 44/211 (20%), Positives = 90/211 (42%), Gaps = 16/211 (7%)
Query: 98 SQDPTQLAEMIFNLLLEEKRILIQAQRAQLEQGEPVLETPVESQQHEIESRILDLRAMME 157
+QD +L EM +E + A RA L E ++ ++ ++ E
Sbjct: 624 AQDKAKLLEM------QESIKDLSAIRADLANKLAEEERAKKAVLKDLSDLTAQAKSRDE 677
Query: 158 KLVKSISQLKDQQDVFCFRYKIQAKGKTPSLDPHQTKEQKILQETLNELDKRRKEVLDAS 217
+ I+QLK ++DV ++ + K T SL +TK ++ +QE + K + E +
Sbjct: 678 ETATIITQLKLERDV----HQRELKDLTSSLQSVKTKHEQNIQELMKHFKKEKSEAENHI 733
Query: 218 KALLGRLTTLIELLLPKLEEWKAQQQKACIRAPIDHGLEQLETWFTAGAKLLFHLRQLLK 277
+ L + +L E + K+ + ++ +++ D E+L KL + L
Sbjct: 734 RTL--KAESLEEKNMAKIHRGQLEK----LKSQCDRLTEELTQNENENKKLKLKYQCLKD 787
Query: 278 ELKGLSCLVSYQDDPLTKGVDLRNAQVTELL 308
+L+ +S +++ L + + R +LL
Sbjct: 788 QLEEREKHISIEEEHLRRMEEARLQLKDQLL 818
>gi|226443002 jumonji, AT rich interactive domain 1D isoform 3 [Homo
sapiens]
Length = 1482
Score = 37.7 bits (86), Expect = 0.045
Identities = 23/62 (37%), Positives = 33/62 (53%), Gaps = 1/62 (1%)
Query: 661 LRFLYPRIPRDEAFGCYYQEKVNLQER-RKYLKHRLIVVSNRQVDELQQPLELKPEPELE 719
L+ L R+P EA C + + Q+R RK L + RQ+ EL+Q L+ KP PE
Sbjct: 1195 LQRLPVRLPEGEALQCLTERAIGWQDRARKALASEDVTALLRQLAELRQQLQAKPRPEEA 1254
Query: 720 SL 721
S+
Sbjct: 1255 SV 1256
>gi|33356560 jumonji, AT rich interactive domain 1D isoform 2 [Homo
sapiens]
Length = 1539
Score = 37.7 bits (86), Expect = 0.045
Identities = 23/62 (37%), Positives = 33/62 (53%), Gaps = 1/62 (1%)
Query: 661 LRFLYPRIPRDEAFGCYYQEKVNLQER-RKYLKHRLIVVSNRQVDELQQPLELKPEPELE 719
L+ L R+P EA C + + Q+R RK L + RQ+ EL+Q L+ KP PE
Sbjct: 1252 LQRLPVRLPEGEALQCLTERAIGWQDRARKALASEDVTALLRQLAELRQQLQAKPRPEEA 1311
Query: 720 SL 721
S+
Sbjct: 1312 SV 1313
>gi|226442991 jumonji, AT rich interactive domain 1D isoform 1 [Homo
sapiens]
Length = 1570
Score = 37.7 bits (86), Expect = 0.045
Identities = 23/62 (37%), Positives = 33/62 (53%), Gaps = 1/62 (1%)
Query: 661 LRFLYPRIPRDEAFGCYYQEKVNLQER-RKYLKHRLIVVSNRQVDELQQPLELKPEPELE 719
L+ L R+P EA C + + Q+R RK L + RQ+ EL+Q L+ KP PE
Sbjct: 1283 LQRLPVRLPEGEALQCLTERAIGWQDRARKALASEDVTALLRQLAELRQQLQAKPRPEEA 1342
Query: 720 SL 721
S+
Sbjct: 1343 SV 1344
>gi|32699028 V-set and immunoglobulin domain containing 1 [Homo
sapiens]
Length = 387
Score = 37.4 bits (85), Expect = 0.059
Identities = 28/87 (32%), Positives = 41/87 (47%), Gaps = 18/87 (20%)
Query: 704 DELQQPLELKPEPELESLELELGLVPEPELSLDLEPLLKAGLDLGPELESVLESTLEPVI 763
D +Q+P + +P+P E P PE + EP+ LD+ ELE +S LEP
Sbjct: 313 DTIQEP-DYEPKPTQE---------PAPEPAPGSEPMAVPDLDIELELEPETQSELEPEP 362
Query: 764 EPTLCMVSQTVPEPDQGPVSQPVPEPD 790
EP PE + G V +P+ E +
Sbjct: 363 EPE--------PESEPGVVVEPLSEDE 381
>gi|56550043 sarcolemma associated protein [Homo sapiens]
Length = 811
Score = 37.0 bits (84), Expect = 0.077
Identities = 55/237 (23%), Positives = 104/237 (43%), Gaps = 26/237 (10%)
Query: 7 LQNLDSPFQDQLHQLYSHSLLPVDIRQYLAVWIE--DQNWQEAALGSDDSKATMLFFHFL 64
L L Q+ LH+ +++ LA+ E D +WQ AL +D + L
Sbjct: 165 LFQLSQYLQEALHREQMLEQKLATLQRLLAITQEASDTSWQ--ALIDEDRLLSRL----- 217
Query: 65 DQLNYECGRCSQDPESLLLQHNLRKFCRDIQPFSQDPTQLAEMIFNLLLEEKRILIQAQR 124
+ + + CS++ + +LRK +Q + A+ +L+EK I + +
Sbjct: 218 EVMGNQLQACSKNQT----EDSLRKELIALQEDKHNYETTAKESLRRVLQEK-IEVVRKL 272
Query: 125 AQLEQGEPVLETPVESQQHEIESRILDLRAMMEKLVKSISQLKDQQDVFCFRYKIQAKGK 184
+++E+ E + E +LR + K +++++KD D + K+ A+GK
Sbjct: 273 SEVERSLSNTEDECTHLKEMNERTQEELRELANKYNGAVNEIKDLSD----KLKV-AEGK 327
Query: 185 TPSLDPHQTKEQKILQETLNELDKRRKEVLDASKALLG-------RLTTLIELLLPK 234
+ E+K LQ ++E++++ +E+ +AL RLT L E LL K
Sbjct: 328 QEEIQQKGQAEKKELQHKIDEMEEKEQELQAKIEALQADNDFTNERLTALQEHLLSK 384
>gi|154354979 myosin X [Homo sapiens]
Length = 2058
Score = 36.6 bits (83), Expect = 0.10
Identities = 35/140 (25%), Positives = 66/140 (47%), Gaps = 15/140 (10%)
Query: 103 QLAEMIFNLLLEEKRILIQAQRAQLEQGEPVLETPVESQQHEIESRILDLRAMMEKLVKS 162
Q+A ++ LL EKR + + + ++ E + E ++ E E R +LRA E+
Sbjct: 802 QIARRVYRQLLAEKR---EQEEKKKQEEEEKKKREEEERERERERREAELRAQQEE---- 854
Query: 163 ISQLKDQQDVFCFRYKIQAKGKTPSLDPHQTKEQKILQETLNELDKRRKEVLDASKALLG 222
+ + QQ++ + + T L+ + KE K ++E L + KE+ D +
Sbjct: 855 --ETRKQQELEALQKSQKEAELTRELE--KQKENKQVEEIL----RLEKEIEDLQRMKEQ 906
Query: 223 RLTTLIELLLPKLEEWKAQQ 242
+ +L E L KL+E + Q+
Sbjct: 907 QELSLTEASLQKLQERRDQE 926
>gi|31542634 filamin A interacting protein 1 [Homo sapiens]
Length = 1213
Score = 36.6 bits (83), Expect = 0.10
Identities = 30/112 (26%), Positives = 58/112 (51%), Gaps = 14/112 (12%)
Query: 136 TPVESQQHEIESRILD-------LRAMMEKLVKSISQLKDQQDVFCFRYKIQAKGKTPSL 188
T ESQ E+ ++ + LR +EKL K +S+L+ ++ F ++K + L
Sbjct: 398 TKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFS-----KSKSECTQL 452
Query: 189 DPHQTKEQKILQETLNELD--KRRKEVLDASKALLGRLTTLIELLLPKLEEW 238
+ KE+ + ++ LNEL+ K R + L+ S++ L + ++ L KL+ +
Sbjct: 453 HLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSF 504
>gi|109715852 chromosome 6 open reading frame 204 isoform a [Homo
sapiens]
Length = 805
Score = 36.6 bits (83), Expect = 0.10
Identities = 46/195 (23%), Positives = 89/195 (45%), Gaps = 20/195 (10%)
Query: 40 EDQNWQEAALGSDDSKATMLFFHFLDQLNYECGRCSQDPESLLL--QHNLRKFCRDIQPF 97
+++N QEA + ++ L+++ +C QD E+ L+ + ++ +Q
Sbjct: 537 KNKNLQEALIDTEKK---------LEEIKKQC----QDKETQLICQKKKEKELVTTVQSL 583
Query: 98 SQDPTQLAEMIFNL-LLEEKRILIQAQRAQLEQGEPVLETPVESQQHEIESRILDLRAMM 156
Q + E L +L+ K++ Q + L Q ++SQQ EI+ IL++++M
Sbjct: 584 QQKVERCLEDGIRLPMLDAKQL--QNENDNLRQQNETASKIIDSQQDEIDRMILEIQSMQ 641
Query: 157 EKLVK-SISQLKDQQDVFCFRYKIQAKGKTPSLDPHQTKEQKILQETLNELDKRRKEVLD 215
KL K ++ K +++ +Q K + QT E L + E D+ R++ +
Sbjct: 642 GKLSKEKLTTQKMMEELEKKERNVQRLTKALLENQRQTDETCSLLDQGQEPDQSRQQTV- 700
Query: 216 ASKALLGRLTTLIEL 230
SK L LT + +L
Sbjct: 701 LSKRPLFDLTVIDQL 715
>gi|215820635 protein phosphatase 1, regulatory subunit 13 like
[Homo sapiens]
Length = 828
Score = 36.2 bits (82), Expect = 0.13
Identities = 27/83 (32%), Positives = 41/83 (49%), Gaps = 21/83 (25%)
Query: 709 PLELKPEPELESLELELGLVPEPELSLDLEPLLKAG-LDLGPELESVLESTLEPVIEPTL 767
P EL+PEPE+E L L P+L+AG +D GP + + L+P + P
Sbjct: 457 PTELEPEPEIEGL---------------LTPVLEAGDVDEGPVARPLSPTRLQPALPPE- 500
Query: 768 CMVSQTVPEPDQ-GPVSQPVPEP 789
+Q+VPE ++ V +P P
Sbjct: 501 ---AQSVPELEEVARVLAEIPRP 520
>gi|63003907 protein phosphatase 1, regulatory subunit 13 like [Homo
sapiens]
Length = 828
Score = 36.2 bits (82), Expect = 0.13
Identities = 27/83 (32%), Positives = 41/83 (49%), Gaps = 21/83 (25%)
Query: 709 PLELKPEPELESLELELGLVPEPELSLDLEPLLKAG-LDLGPELESVLESTLEPVIEPTL 767
P EL+PEPE+E L L P+L+AG +D GP + + L+P + P
Sbjct: 457 PTELEPEPEIEGL---------------LTPVLEAGDVDEGPVARPLSPTRLQPALPPE- 500
Query: 768 CMVSQTVPEPDQ-GPVSQPVPEP 789
+Q+VPE ++ V +P P
Sbjct: 501 ---AQSVPELEEVARVLAEIPRP 520
>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
Length = 1317
Score = 36.2 bits (82), Expect = 0.13
Identities = 59/290 (20%), Positives = 123/290 (42%), Gaps = 46/290 (15%)
Query: 70 ECGRCSQDPESLLLQHNLRKFCRDIQPFSQDPTQLAEMIFNLLLEEKRILIQAQR---AQ 126
EC +C D ES LL+ + + D+ QD ++ + + L +E+++ Q
Sbjct: 862 ECLKCEHDKESRLLEKH-DESVTDVTEVPQDFEKIKPVEYRLQYKERQLQYLLQNHLPTL 920
Query: 127 LEQGEPVLE------TPVESQQHEIESRILDLRAMMEKLVKSISQLKDQQDVFCFRYKIQ 180
LE+ + E +++ +++E + + + + + +QL+ Q F F
Sbjct: 921 LEEKQRAFEILDRGPLSLDNTLYQVEKEMEEKEEQLAQYQANANQLQKLQATFEF----- 975
Query: 181 AKGKTPSLDPHQTKEQKILQETLNELDKRRKEVLDASKALLGRLTTLIE---LLLPKLEE 237
T ++ + K +K +E L +K+++E L+ + A L R + ++ L ++EE
Sbjct: 976 ----TANIARQEEKVRKKEKEILESREKQQREALERALARLERRHSALQRHSTLGMEIEE 1031
Query: 238 WK--------AQQQKACIRAPIDHGLEQLETWFTAGAKLLFHLRQLLKELKGL------- 282
+ ++++ ++A ++ E LE + L+Q + E+ G+
Sbjct: 1032 QRQKLASLNSGSREQSGLQASLEAEQEALEKDQERLEYEIQQLKQKIYEVDGVQKDHHGT 1091
Query: 283 --------SCLVSYQDDPLTKGVDLR-NAQVTELLQRLLHRAFVVETQPC 323
S VS + L +D R NA + E +QR L V ++ C
Sbjct: 1092 LEGKVASSSLPVSAEKSHLVPLMDARINAYIEEEVQRRLQDLHRVISEGC 1141
>gi|156151379 suppressor of IKK epsilon isoform 1 [Homo sapiens]
Length = 211
Score = 36.2 bits (82), Expect = 0.13
Identities = 27/94 (28%), Positives = 45/94 (47%), Gaps = 10/94 (10%)
Query: 677 YYQEKVNLQERRKYLKHRLIVVSNRQVDELQQ---PLELKPEPELESLELELGLVPEPEL 733
Y ++ ++++ KY H L+ N Q+ +LQQ L + E ++LEL + + L
Sbjct: 58 YQEDASDMKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQML 117
Query: 734 SL-------DLEPLLKAGLDLGPELESVLESTLE 760
L D EP+LKA E+ES ++ E
Sbjct: 118 QLMVAKKAVDAEPVLKAHQSHSAEIESQIDRICE 151
>gi|156151377 suppressor of IKK epsilon isoform 2 [Homo sapiens]
Length = 207
Score = 36.2 bits (82), Expect = 0.13
Identities = 27/94 (28%), Positives = 45/94 (47%), Gaps = 10/94 (10%)
Query: 677 YYQEKVNLQERRKYLKHRLIVVSNRQVDELQQ---PLELKPEPELESLELELGLVPEPEL 733
Y ++ ++++ KY H L+ N Q+ +LQQ L + E ++LEL + + L
Sbjct: 54 YQEDASDMKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQML 113
Query: 734 SL-------DLEPLLKAGLDLGPELESVLESTLE 760
L D EP+LKA E+ES ++ E
Sbjct: 114 QLMVAKKAVDAEPVLKAHQSHSAEIESQIDRICE 147
>gi|153945736 keratin 27 [Homo sapiens]
Length = 459
Score = 35.8 bits (81), Expect = 0.17
Identities = 47/184 (25%), Positives = 80/184 (43%), Gaps = 26/184 (14%)
Query: 32 RQYLAVWIEDQNWQEAALGSDDSKATMLFFHFLDQLNYECGRCSQDPESLLL-QHNLRKF 90
R+ W +++ SDD+ AT + L ++ + +SLL +H+L
Sbjct: 272 RRDAEAWFNEKSASLQQQISDDAGATTSARNELIEMKRTLQTLEIELQSLLATKHSLE-- 329
Query: 91 CRDIQPFSQDPTQLAEMIFNLLLEEKRILIQAQRAQLEQGEPVLETPVESQQHEIESRIL 150
C + S QLA+ IQAQ LE+ + T E Q+ E E ++L
Sbjct: 330 CSLTETESNYCAQLAQ-------------IQAQIGALEEQLHQVRTETEGQKLEYE-QLL 375
Query: 151 DLRAMMEKLVKSISQLKDQQDVFCFRYKIQAKGKTPSLDPHQTKEQK---ILQETLNELD 207
D++ +EK +++ L D +D C +K K +QTK+ I++ + E+D
Sbjct: 376 DIKVHLEKEIETYCLLIDGEDGSC------SKSKGYGGPGNQTKDSSKTTIVKTVVEEID 429
Query: 208 KRRK 211
R K
Sbjct: 430 PRGK 433
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.136 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,081,278
Number of Sequences: 37866
Number of extensions: 1709822
Number of successful extensions: 6191
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 142
Number of HSP's that attempted gapping in prelim test: 5834
Number of HSP's gapped (non-prelim): 416
length of query: 851
length of database: 18,247,518
effective HSP length: 111
effective length of query: 740
effective length of database: 14,044,392
effective search space: 10392850080
effective search space used: 10392850080
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.