BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|4885369 granzyme M precursor [Homo sapiens] (257 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|4885369 granzyme M precursor [Homo sapiens] 519 e-148 gi|42544239 complement factor D preproprotein [Homo sapiens] 185 3e-47 gi|47551347 protease, serine-like 1 [Homo sapiens] 171 6e-43 gi|4504235 granzyme K precursor [Homo sapiens] 156 1e-38 gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo s... 150 1e-36 gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sap... 148 5e-36 gi|221625528 granzyme B precursor [Homo sapiens] 144 1e-34 gi|5453676 granzyme A precursor [Homo sapiens] 144 1e-34 gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 139 2e-33 gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens] 139 2e-33 gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 139 2e-33 gi|15529990 granzyme H [Homo sapiens] 139 2e-33 gi|4503149 cathepsin G preproprotein [Homo sapiens] 139 3e-33 gi|15559207 elastase 2A preproprotein [Homo sapiens] 138 5e-33 gi|4503549 neutrophil elastase preproprotein [Homo sapiens] 137 7e-33 gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprot... 136 2e-32 gi|71361688 myeloblastin [Homo sapiens] 136 2e-32 gi|170932492 transmembrane protease, serine 5 [Homo sapiens] 136 2e-32 gi|11496281 kallikrein 13 precursor [Homo sapiens] 134 6e-32 gi|29244926 corin [Homo sapiens] 134 8e-32 gi|33695155 hepsin [Homo sapiens] 134 1e-31 gi|4504481 hepsin [Homo sapiens] 134 1e-31 gi|4505881 plasminogen [Homo sapiens] 132 3e-31 gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens] 130 9e-31 gi|58331209 chymotrypsin-like elastase family, member 1 [Homo sa... 130 1e-30 gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo sa... 129 2e-30 gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo sa... 129 2e-30 gi|11342670 azurocidin 1 preproprotein [Homo sapiens] 129 3e-30 gi|21464127 kallikrein 8 isoform 2 [Homo sapiens] 129 3e-30 gi|23957702 transmembrane protease, serine 6 [Homo sapiens] 129 3e-30 >gi|4885369 granzyme M precursor [Homo sapiens] Length = 257 Score = 519 bits (1337), Expect = e-148 Identities = 257/257 (100%), Positives = 257/257 (100%) Query: 1 MEACVSSLLVLALGALSVGSSFGTQIIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKW 60 MEACVSSLLVLALGALSVGSSFGTQIIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKW Sbjct: 1 MEACVSSLLVLALGALSVGSSFGTQIIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKW 60 Query: 61 VLTAAHCLAQRMAQLRLVLGLHTLDSPGLTFHIKAAIQHPRYKPVPALENDLALLQLDGK 120 VLTAAHCLAQRMAQLRLVLGLHTLDSPGLTFHIKAAIQHPRYKPVPALENDLALLQLDGK Sbjct: 61 VLTAAHCLAQRMAQLRLVLGLHTLDSPGLTFHIKAAIQHPRYKPVPALENDLALLQLDGK 120 Query: 121 VKPSRTIRPLALPSKRQVVAAGTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNSR 180 VKPSRTIRPLALPSKRQVVAAGTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNSR Sbjct: 121 VKPSRTIRPLALPSKRQVVAAGTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNSR 180 Query: 181 FWNGSLSPSMVCLAADSKDQAPCKGDSGGPLVCGKGRVLAGVLSFSSRVCTDIFKPPVAT 240 FWNGSLSPSMVCLAADSKDQAPCKGDSGGPLVCGKGRVLAGVLSFSSRVCTDIFKPPVAT Sbjct: 181 FWNGSLSPSMVCLAADSKDQAPCKGDSGGPLVCGKGRVLAGVLSFSSRVCTDIFKPPVAT 240 Query: 241 AVAPYVSWIRKVTGRSA 257 AVAPYVSWIRKVTGRSA Sbjct: 241 AVAPYVSWIRKVTGRSA 257 >gi|42544239 complement factor D preproprotein [Homo sapiens] Length = 253 Score = 185 bits (470), Expect = 3e-47 Identities = 103/248 (41%), Positives = 150/248 (60%), Gaps = 9/248 (3%) Query: 9 LVLALGALSVGSSFGTQIIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKWVLTAAHCL 68 +++ LGA + + +I+GGRE H+RPYMAS+Q NG+HLCGGVLV +WVL+AAHCL Sbjct: 9 VLVLLGAAACAAPPRGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCL 68 Query: 69 AQRM-AQLRLVLGLHTLDSPGLT---FHIKAAIQHPRYKPVPALENDLALLQLDGKVKPS 124 +++++LG H+L P + + + A+ HP +P +++DL LLQL K Sbjct: 69 EDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQP-DTIDHDLLLLQLSEKATLG 127 Query: 125 RTIRPLALPSKRQVVAAGTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNSRFWNG 184 +RPL + VA GT C +AGWG+ + GR L+ + L VLD CN +G Sbjct: 128 PAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHHDG 187 Query: 185 SLSPSMVCLAADSKDQAPCKGDSGGPLVCGKGRVLAGVLSFSSRVCTDIFKPPVATAVAP 244 +++ ++C ++ +D CKGDSGGPLVC G VL GV++ SRVC + KP + T VA Sbjct: 188 AITERLMCAESNRRDS--CKGDSGGPLVC--GGVLEGVVTSGSRVCGNRKKPGIYTRVAS 243 Query: 245 YVSWIRKV 252 Y +WI V Sbjct: 244 YAAWIDSV 251 >gi|47551347 protease, serine-like 1 [Homo sapiens] Length = 283 Score = 171 bits (433), Expect = 6e-43 Identities = 106/243 (43%), Positives = 140/243 (57%), Gaps = 11/243 (4%) Query: 21 SFGTQIIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKWVLTAAHCLAQRMAQLRL-VL 79 S+G QIIGG EV PHSRPYMAS++ G H CGG L+ +WV++AAHC + R + L VL Sbjct: 29 SWGAQIIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVL 88 Query: 80 GLHTLDSPGLT---FHIKAAIQHPRYKPVPALENDLALLQLDGKVKPSRTIRPLALPSKR 136 G H L + T F I A HP Y P+ ND+ LL+L+G + L LP +R Sbjct: 89 GAHVLSTAEPTQQVFGIDALTTHPDYHPM-THANDICLLRLNGSAVLGPAVGLLRLPGRR 147 Query: 137 -QVVAAGTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNSRFWNGSLSPSMVCL-A 194 + AGTRC +AGWG L L E ++VLD +CN+S W G L+ +M+C + Sbjct: 148 ARPPTAGTRCRVAGWGFVSDFEELPPGLMEAKVRVLDPDVCNSS--WKGHLTLTMLCTRS 205 Query: 195 ADSKDQAPCKGDSGGPLVCGKGRVLAGVLSFSSRVCTDIFKPPVATAVAPYVSWIRKVTG 254 DS + C DSGGPLVC + R G++SFS C D P V T V+ +V+WI V Sbjct: 206 GDSHRRGFCSADSGGPLVC-RNRA-HGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVR 263 Query: 255 RSA 257 RS+ Sbjct: 264 RSS 266 >gi|4504235 granzyme K precursor [Homo sapiens] Length = 264 Score = 156 bits (395), Expect = 1e-38 Identities = 102/254 (40%), Positives = 145/254 (57%), Gaps = 16/254 (6%) Query: 7 SLLVLALGALSVGSSFGTQIIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKWVLTAAH 66 SL L +GA F +IIGG+EV PHSRP+MAS+Q G H+CGGVL+ P+WVLTAAH Sbjct: 8 SLFFLIVGAYMTHVCFNMEIIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAH 67 Query: 67 CLAQ--RMAQLRLVLGLHTL---DSPGLTFHIKAAIQHPRYKPVPALENDLALLQLDGKV 121 C + + +VLG H+L ++ T IK I R P ND+ L++L Sbjct: 68 CQYRFTKGQSPTVVLGAHSLSKNEASKQTLEIKKFIPFSRVTSDPQ-SNDIMLVKLQTAA 126 Query: 122 KPSRTIRPLALPSKRQVVAAGTRCSMAGWGLTHQGG-RLSRVLRELDLQVLDTRMCNNSR 180 K ++ ++ L + SK + +GT+C + GWG T R S LRE+ + VL ++CN+ Sbjct: 127 KLNKHVKMLHIRSKTS-LRSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQS 185 Query: 181 FWNGS--LSPSMVCLAADSKDQA-PCKGDSGGPLVCGKGRVLAGVLSFSSRVCTDIFKPP 237 ++NG ++ MVC A D+K Q CKGDSGGPL+C KG V ++S C KP Sbjct: 186 YYNGDPFITKDMVC-AGDAKGQKDSCKGDSGGPLIC-KG-VFHAIVS-GGHECGVATKPG 241 Query: 238 VATAVA-PYVSWIR 250 + T + Y +WI+ Sbjct: 242 IYTLLTKKYQTWIK 255 >gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo sapiens] Length = 254 Score = 150 bits (378), Expect = 1e-36 Identities = 93/253 (36%), Positives = 134/253 (52%), Gaps = 17/253 (6%) Query: 8 LLVLALGALSVGSSFGTQIIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKWVLTAAHC 67 L++ G+L GS +QII G + PHS+P+ A+L C GVLVHP+WVL+AAHC Sbjct: 15 LILGVAGSLVSGSC--SQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHC 72 Query: 68 LAQRMAQLRLVLGLHTLDS---PGLTF-HIKAAIQHPRYKPVPALENDLALLQLDGKVKP 123 + LGLH+L++ PG +++HP Y P L NDL L++LD V Sbjct: 73 FQN---SYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNR-PLLANDLMLIKLDESVSE 128 Query: 124 SRTIRPLALPSKRQVVAAGTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNSRFWN 183 S TIR +++ S Q AG C ++GWGL GR+ VL+ +++ V+ +C S+ ++ Sbjct: 129 SDTIRSISIAS--QCPTAGNSCLVSGWGLL-ANGRMPTVLQCVNVSVVSEEVC--SKLYD 183 Query: 184 GSLSPSMVCLAADSKDQAPCKGDSGGPLVCGKGRVLAGVLSFSSRVCTDIFKPPVATAVA 243 PSM C + C GDSGGPL+C L G++SF C + P V T + Sbjct: 184 PLYHPSMFCAGGGHDQKDSCNGDSGGPLIC--NGYLQGLVSFGKAPCGQVGVPGVYTNLC 241 Query: 244 PYVSWIRKVTGRS 256 + WI K S Sbjct: 242 KFTEWIEKTVQAS 254 >gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sapiens] Length = 454 Score = 148 bits (373), Expect = 5e-36 Identities = 89/257 (34%), Positives = 137/257 (53%), Gaps = 9/257 (3%) Query: 2 EACVSSLLV-LALGALSVGSSFGTQIIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKW 60 E C S +V L A + ++I+GG + P+ ASLQ G HLCGG ++ P W Sbjct: 192 EGCASGHVVTLQCTACGHRRGYSSRIVGGNMSLLSQWPWQASLQFQGYHLCGGSVITPLW 251 Query: 61 VLTAAHCLAQRM--AQLRLVLGL-HTLDSPGLTFHIKAAIQHPRYKPVPALENDLALLQL 117 ++TAAHC+ + +GL LD+P + ++ + H +YKP L ND+AL++L Sbjct: 252 IITAAHCVYDLYLPKSWTIQVGLVSLLDNPAPSHLVEKIVYHSKYKP-KRLGNDIALMKL 310 Query: 118 DGKVKPSRTIRPLALPSKRQVVAAGTRCSMAGWGLTHQG-GRLSRVLRELDLQVLDTRMC 176 G + + I+P+ LP+ + G C +GWG T G G S VL + ++ ++C Sbjct: 311 AGPLTFNEMIQPVCLPNSEENFPDGKVCWTSGWGATEDGAGDASPVLNHAAVPLISNKIC 370 Query: 177 NNSRFWNGSLSPSMVCLAADSKDQAPCKGDSGGPLVCGKGRV--LAGVLSFSSRVCTDIF 234 N+ + G +SPSM+C + C+GDSGGPLVC + R+ L G SF C ++ Sbjct: 371 NHRDVYGGIISPSMLCAGYLTGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIG-CAEVN 429 Query: 235 KPPVATAVAPYVSWIRK 251 KP V T V ++ WI + Sbjct: 430 KPGVYTRVTSFLDWIHE 446 >gi|221625528 granzyme B precursor [Homo sapiens] Length = 247 Score = 144 bits (362), Expect = 1e-34 Identities = 91/255 (35%), Positives = 132/255 (51%), Gaps = 20/255 (7%) Query: 9 LVLALGALSVGSSFGTQIIGGREVIPHSRPYMASLQ---RNGSHLCGGVLVHPKWVLTAA 65 ++L L L + + +IIGG E PHSRPYMA L + CGG L+ +VLTAA Sbjct: 4 ILLLLAFLLLPRADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAA 63 Query: 66 HCLAQRMAQLRLVLGLHTLDSPGLT---FHIKAAIQHPRYKPVPALENDLALLQLDGKVK 122 HC + + + LG H + T +K I HP Y P ND+ LLQL+ K K Sbjct: 64 HCWG---SSINVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNP-KNFSNDIMLLQLERKAK 119 Query: 123 PSRTIRPLALPSKRQVVAAGTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNS--R 180 +R ++PL LPS + V G CS+AGWG T G+ S L+E+ + V + R C + Sbjct: 120 RTRAVQPLRLPSNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRH 179 Query: 181 FWNGSLSPSMVCLAADSKDQAPCKGDSGGPLVCGKGRVLAGVLSFSSRVCTDIFKPPVAT 240 +++ ++ +C+ + KGDSGGPLVC K V G++S+ + P T Sbjct: 180 YYDSTIE---LCVGDPEIKKTSFKGDSGGPLVCNK--VAQGIVSYGR---NNGMPPRACT 231 Query: 241 AVAPYVSWIRKVTGR 255 V+ +V WI+K R Sbjct: 232 KVSSFVHWIKKTMKR 246 >gi|5453676 granzyme A precursor [Homo sapiens] Length = 262 Score = 144 bits (362), Expect = 1e-34 Identities = 91/252 (36%), Positives = 131/252 (51%), Gaps = 12/252 (4%) Query: 5 VSSLLVLALGALSVGSSFGTQIIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKWVLTA 64 ++S L + + L + +IIGG EV PHSRPYM L + +C G L+ WVLTA Sbjct: 8 LASSLSVVVSLLLIPEDVCEKIIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTA 67 Query: 65 AHCLAQRMAQLRLVLGLHTLDSPGLTFHI---KAAIQHPRYKPVPALENDLALLQLDGKV 121 AHC + +Q+ +LG H++ T I K +P Y P E DL LLQL K Sbjct: 68 AHCNLNKRSQV--ILGAHSITREEPTKQIMLVKKEFPYPCYDPATR-EGDLKLLQLTEKA 124 Query: 122 KPSRTIRPLALPSKRQVVAAGTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNSRF 181 K ++ + L LP K V GT C +AGWG TH S LRE+++ ++D ++CN+ Sbjct: 125 KINKYVTILHLPKKGDDVKPGTMCQVAGWGRTHNSASWSDTLREVNITIIDRKVCNDRNH 184 Query: 182 WNGS--LSPSMVCLAADSKDQAPCKGDSGGPLVCGKGRVLAGVLSFS-SRVCTDIFKPPV 238 +N + + +MVC + + C GDSG PL+C V GV SF C D P V Sbjct: 185 YNFNPVIGMNMVCAGSLRGGRDSCNGDSGSPLLC--EGVFRGVTSFGLENKCGDPRGPGV 242 Query: 239 ATAVA-PYVSWI 249 ++ +++WI Sbjct: 243 YILLSKKHLNWI 254 >gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens] Length = 250 Score = 139 bits (351), Expect = 2e-33 Identities = 90/254 (35%), Positives = 134/254 (52%), Gaps = 18/254 (7%) Query: 5 VSSLLVLALGALSVGSSFGTQIIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKWVLTA 64 + L++LAL VG T+II G E PHS+P+ A+L LCG L+ P+W+LTA Sbjct: 3 ILQLILLALATGLVGGE--TRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTA 60 Query: 65 AHCLAQRMAQLRLVLGLHTLDSPGLTFHIKAAIQ---HPRYK---PVPALENDLALLQLD 118 AHCL R + LG H L + A + HP + P ND+ L+++ Sbjct: 61 AHCLKPRYI---VHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMA 117 Query: 119 GKVKPSRTIRPLALPSKRQVVAAGTRCSMAGWGLTHQGG-RLSRVLRELDLQVLDTRMCN 177 V + +RPL L S+ V AGT C ++GWG T RL LR ++ +++ + C Sbjct: 118 SPVSITWAVRPLTLSSR--CVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCE 175 Query: 178 NSRFWNGSLSPSMVCLAADSKDQAPCKGDSGGPLVCGKGRVLAGVLSFSSRVCTDIFKPP 237 N+ + G+++ +MVC + + C+GDSGGPLVC + L G++S+ C KP Sbjct: 176 NA--YPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQS--LQGIISWGQDPCAITRKPG 231 Query: 238 VATAVAPYVSWIRK 251 V T V YV WI++ Sbjct: 232 VYTKVCKYVDWIQE 245 >gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens] Length = 282 Score = 139 bits (351), Expect = 2e-33 Identities = 90/254 (35%), Positives = 134/254 (52%), Gaps = 18/254 (7%) Query: 5 VSSLLVLALGALSVGSSFGTQIIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKWVLTA 64 + L++LAL VG T+II G E PHS+P+ A+L LCG L+ P+W+LTA Sbjct: 35 ILQLILLALATGLVGGE--TRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTA 92 Query: 65 AHCLAQRMAQLRLVLGLHTLDSPGLTFHIKAAIQ---HPRYK---PVPALENDLALLQLD 118 AHCL R + LG H L + A + HP + P ND+ L+++ Sbjct: 93 AHCLKPRYI---VHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMA 149 Query: 119 GKVKPSRTIRPLALPSKRQVVAAGTRCSMAGWGLTHQGG-RLSRVLRELDLQVLDTRMCN 177 V + +RPL L S+ V AGT C ++GWG T RL LR ++ +++ + C Sbjct: 150 SPVSITWAVRPLTLSSR--CVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCE 207 Query: 178 NSRFWNGSLSPSMVCLAADSKDQAPCKGDSGGPLVCGKGRVLAGVLSFSSRVCTDIFKPP 237 N+ + G+++ +MVC + + C+GDSGGPLVC + L G++S+ C KP Sbjct: 208 NA--YPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQS--LQGIISWGQDPCAITRKPG 263 Query: 238 VATAVAPYVSWIRK 251 V T V YV WI++ Sbjct: 264 VYTKVCKYVDWIQE 277 >gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens] Length = 250 Score = 139 bits (351), Expect = 2e-33 Identities = 90/254 (35%), Positives = 134/254 (52%), Gaps = 18/254 (7%) Query: 5 VSSLLVLALGALSVGSSFGTQIIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKWVLTA 64 + L++LAL VG T+II G E PHS+P+ A+L LCG L+ P+W+LTA Sbjct: 3 ILQLILLALATGLVGGE--TRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTA 60 Query: 65 AHCLAQRMAQLRLVLGLHTLDSPGLTFHIKAAIQ---HPRYK---PVPALENDLALLQLD 118 AHCL R + LG H L + A + HP + P ND+ L+++ Sbjct: 61 AHCLKPRYI---VHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMA 117 Query: 119 GKVKPSRTIRPLALPSKRQVVAAGTRCSMAGWGLTHQGG-RLSRVLRELDLQVLDTRMCN 177 V + +RPL L S+ V AGT C ++GWG T RL LR ++ +++ + C Sbjct: 118 SPVSITWAVRPLTLSSR--CVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCE 175 Query: 178 NSRFWNGSLSPSMVCLAADSKDQAPCKGDSGGPLVCGKGRVLAGVLSFSSRVCTDIFKPP 237 N+ + G+++ +MVC + + C+GDSGGPLVC + L G++S+ C KP Sbjct: 176 NA--YPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQS--LQGIISWGQDPCAITRKPG 231 Query: 238 VATAVAPYVSWIRK 251 V T V YV WI++ Sbjct: 232 VYTKVCKYVDWIQE 245 >gi|15529990 granzyme H [Homo sapiens] Length = 246 Score = 139 bits (351), Expect = 2e-33 Identities = 95/253 (37%), Positives = 130/253 (51%), Gaps = 19/253 (7%) Query: 10 VLALGALSVGSSFGTQIIGGREVIPHSRPYMAS---LQRNGSHLCGGVLVHPKWVLTAAH 66 +L L L + +IIGG E PHSRPYMA LQ CGG+LV +VLTAAH Sbjct: 5 LLLLAFLLTPGAGTEEIIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLTAAH 64 Query: 67 CLAQRMAQLRLVLGLHTLDSPGLT---FHIKAAIQHPRYKPVPALENDLALLQLDGKVKP 123 C + + + LG H + T +K I HP Y P ND+ LLQL+ K K Sbjct: 65 CQG---SSINVTLGAHNIKEQERTQQFIPVKRPIPHPAYNP-KNFSNDIMLLQLERKAKW 120 Query: 124 SRTIRPLALPSKRQVVAAGTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNSRFWN 183 + +RPL LPS + V G CS+AGWG L+ L+E+ L V + C R ++ Sbjct: 121 TTAVRPLRLPSSKAQVKPGQLCSVAGWGYVSM-STLATTLQEVLLTV--QKDCQCERLFH 177 Query: 184 GSLS-PSMVCLAADSKDQAPCKGDSGGPLVCGKGRVLAGVLSFSSRVCTDIFKPPVATAV 242 G+ S + +C+ K Q KGDSGGPLVC V G+LS+ ++ T P V V Sbjct: 178 GNYSRATEICVGDPKKTQTGFKGDSGGPLVCKD--VAQGILSYGNKKGT---PPGVYIKV 232 Query: 243 APYVSWIRKVTGR 255 + ++ WI++ R Sbjct: 233 SHFLPWIKRTMKR 245 >gi|4503149 cathepsin G preproprotein [Homo sapiens] Length = 255 Score = 139 bits (349), Expect = 3e-33 Identities = 99/250 (39%), Positives = 138/250 (55%), Gaps = 21/250 (8%) Query: 8 LLVLALGALSVGSSFGTQIIGGREVIPHSRPYMASLQRN---GSHLCGGVLVHPKWVLTA 64 LL+L L G+ G +IIGGRE PHSRPYMA LQ G CGG LV +VLTA Sbjct: 4 LLLLLAFLLPTGAEAG-EIIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTA 62 Query: 65 AHCLAQRMAQLRLVLGLHTLDSPGLTF-HIKA--AIQHPRYKPVPALENDLALLQLDGKV 121 AHC + + + LG H + T HI A AI+HP+Y ++ND+ LLQL +V Sbjct: 63 AHCWG---SNINVTLGAHNIQRRENTQQHITARRAIRHPQYNQ-RTIQNDIMLLQLSRRV 118 Query: 122 KPSRTIRPLALPSKRQVVAAGTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNSRF 181 + +R + P+ALP ++ + GT C++AGWG R + LRE+ L+V R C R Sbjct: 119 RRNRNVNPVALPRAQEGLRPGTLCTVAGWGRVSM-RRGTDTLREVQLRVQRDRQC--LRI 175 Query: 182 WNGSLSP-SMVCLAADSKDQAPCKGDSGGPLVCGKGRVLAGVLSFSSRVCTDIFKPPVAT 240 + GS P +C+ + +A KGDSGGPL+C V G++S+ + P V T Sbjct: 176 F-GSYDPRRQICVGDRRERKAAFKGDSGGPLLC--NNVAHGIVSYGK---SSGVPPEVFT 229 Query: 241 AVAPYVSWIR 250 V+ ++ WIR Sbjct: 230 RVSSFLPWIR 239 >gi|15559207 elastase 2A preproprotein [Homo sapiens] Length = 269 Score = 138 bits (347), Expect = 5e-33 Identities = 92/261 (35%), Positives = 132/261 (50%), Gaps = 18/261 (6%) Query: 8 LLVLALGALSVGSS----FGTQIIGGREVIPHSRPYMASLQRNGS----HLCGGVLVHPK 59 L L GALS G + T+++GG E P+S P+ SLQ + + H CGG L+ Sbjct: 7 LSTLVAGALSCGDPTYPPYVTRVVGGEEARPNSWPWQVSLQYSSNGKWYHTCGGSLIANS 66 Query: 60 WVLTAAHCLAQRMAQLRLVLGLHTL---DSPGLTFHIKAAIQHPRYKPVPALE-NDLALL 115 WVLTAAHC++ R+ LG H L +S L + + H + + ND+ALL Sbjct: 67 WVLTAAHCISSSRTY-RVGLGRHNLYVAESGSLAVSVSKIVVHKDWNSNQISKGNDIALL 125 Query: 116 QLDGKVKPSRTIRPLALPSKRQVVAAGTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRM 175 +L V + I+ LP ++ C + GWG G + VL++ L V+D Sbjct: 126 KLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGAVPDVLQQGRLLVVDYAT 185 Query: 176 CNNSRFWNGSLSPSMVCLAADSKDQAPCKGDSGGPLVC--GKGR-VLAGVLSFSSRV-CT 231 C++S +W S+ SM+C D + C GDSGGPL C GR + G++SF SR+ C Sbjct: 186 CSSSAWWGSSVKTSMICAGGDGVISS-CNGDSGGPLNCQASDGRWQVHGIVSFGSRLGCN 244 Query: 232 DIFKPPVATAVAPYVSWIRKV 252 KP V T V+ Y+ WI V Sbjct: 245 YYHKPSVFTRVSNYIDWINSV 265 >gi|4503549 neutrophil elastase preproprotein [Homo sapiens] Length = 267 Score = 137 bits (346), Expect = 7e-33 Identities = 87/257 (33%), Positives = 130/257 (50%), Gaps = 23/257 (8%) Query: 3 ACVSSLLVLALGALSVGSSFGTQIIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKWVL 62 ACV L+L G++ ++I+GGR PH+ P+M SLQ G H CG L+ P +V+ Sbjct: 13 ACVLPALLLG------GTALASEIVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVM 66 Query: 63 TAAHCLAQ-RMAQLRLVLGLHTLDSPGLTFHIKAA--IQHPRYKPVPALENDLALLQLDG 119 +AAHC+A + +R+VLG H L T + A I Y PV L ND+ +LQL+G Sbjct: 67 SAAHCVANVNVRAVRVVLGAHNLSRREPTRQVFAVQRIFENGYDPVNLL-NDIVILQLNG 125 Query: 120 KVKPSRTIRPLALPSKRQVVAAGTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNS 179 + ++ LP++ + + G +C GWGL + ++ VL+EL++ V+ T +C S Sbjct: 126 SATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVV-TSLCRRS 184 Query: 180 RFWNGSLSPSMVCLAADSKDQAPCKGDSGGPLVCGKGRVLAGVLSFSSRVCTDIFKPPVA 239 VC + C GDSG PLVC ++ G+ SF C P Sbjct: 185 N----------VCTLVRGRQAGVCFGDSGSPLVC--NGLIHGIASFVRGGCASGLYPDAF 232 Query: 240 TAVAPYVSWIRKVTGRS 256 VA +V+WI + RS Sbjct: 233 APVAQFVNWIDSIIQRS 249 >gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprotein [Homo sapiens] Length = 256 Score = 136 bits (343), Expect = 2e-32 Identities = 89/263 (33%), Positives = 133/263 (50%), Gaps = 24/263 (9%) Query: 8 LLVLALGALSVGSSFGTQIIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKWVLTAAHC 67 LL L+ S + G +++ G E PHS+P+ +L G CG L+ P WVL+AAHC Sbjct: 4 LLTLSFLLASTAAQDGDKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWVLSAAHC 63 Query: 68 LAQRMAQLRLVLGLHTL---DSPGLTFHIKAAIQHPRYKPVPALENDLALLQLDGKVKPS 124 ++ M R+ LG H L D P I HPRY+ + ND+ LL+L + + Sbjct: 64 QSRFM---RVRLGEHNLRKRDGPEQLRTTSRVIPHPRYE-ARSHRNDIMLLRLVQPARLN 119 Query: 125 RTIRPLALPSKRQVVAAGTRCSMAGWGLTHQ------GGRLSRV-----LRELDLQVLDT 173 +RP LP++ G C ++GWGL G S+V L ++ ++ Sbjct: 120 PQVRPAVLPTR--CPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISD 177 Query: 174 RMCNNSRFWNGSLSPSMVCLAADSKDQAPCKGDSGGPLVCGKGRVLAGVLSFSSRVCTDI 233 C+ S + G L+ +MVC A+ + C+GDSGGPLVC G +L G++S+ C + Sbjct: 178 TSCDKS--YPGRLTNTMVCAGAEGRGAESCEGDSGGPLVC--GGILQGIVSWGDVPCDNT 233 Query: 234 FKPPVATAVAPYVSWIRKVTGRS 256 KP V T V Y+ WIR+ R+ Sbjct: 234 TKPGVYTKVCHYLEWIRETMKRN 256 >gi|71361688 myeloblastin [Homo sapiens] Length = 256 Score = 136 bits (342), Expect = 2e-32 Identities = 92/254 (36%), Positives = 123/254 (48%), Gaps = 18/254 (7%) Query: 7 SLLVLALGALSVGSSFGTQIIGGREVIPHSRPYMASLQRNG---SHLCGGVLVHPKWVLT 63 +L + L L G++ +I+GG E PHSRPYMASLQ G SH CGG L+HP +VLT Sbjct: 9 ALASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLT 68 Query: 64 AAHCLAQRMAQL-RLVLGLHTLDSPGLT-FHIKAAIQHPRYKPVPALENDLALLQLDGKV 121 AAHCL +L +VLG H + + T H A ND+ L+QL Sbjct: 69 AAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPA 128 Query: 122 KPSRTIRPLALPSKRQVVAAGTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNSRF 181 S ++ + LP + Q V GT+C GWG ++VL+EL++ V+ T C Sbjct: 129 NLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVV-TFFCR---- 183 Query: 182 WNGSLSPSMVCLAADSKDQAPCKGDSGGPLVCGKGRVLAGVLSFSSRVCTDIFKPPVATA 241 P +C + C GDSGGPL+C ++ G+ SF C P T Sbjct: 184 ------PHNICTFVPRRKAGICFGDSGGPLIC--DGIIQGIDSFVIWGCATRLFPDFFTR 235 Query: 242 VAPYVSWIRKVTGR 255 VA YV WIR R Sbjct: 236 VALYVDWIRSTLRR 249 >gi|170932492 transmembrane protease, serine 5 [Homo sapiens] Length = 457 Score = 136 bits (342), Expect = 2e-32 Identities = 83/235 (35%), Positives = 129/235 (54%), Gaps = 11/235 (4%) Query: 24 TQIIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKWVLTAAHCL----AQRMAQLRLVL 79 ++I+GG+ V P P+ AS+ H CGG ++ P+WV+TAAHC+ R++ R+ Sbjct: 216 SRIVGGQSVAPGRWPWQASVALGFRHTCGGSVLAPRWVVTAAHCMHSFRLARLSSWRVHA 275 Query: 80 GL--HTLDSPGLTFHIKAAIQHPRYKPVPALENDLALLQLDGKVKPSRTIRPLALPSKRQ 137 GL H+ P ++ I HP Y + D+ALL+L + S T+ + LP+K Q Sbjct: 276 GLVSHSAVRPHQGALVERIIPHPLYS-AQNHDYDVALLRLQTALNFSDTVGAVCLPAKEQ 334 Query: 138 VVAAGTRCSMAGWGLTHQGGRLSR-VLRELDLQVLDTRMCNNSRFWNGSLSPSMVCLAAD 196 G+RC ++GWG TH S +L++ + + T++CN+S ++G+L+P M+C Sbjct: 335 HFPKGSRCWVSGWGHTHPSHTYSSDMLQDTVVPLFSTQLCNSSCVYSGALTPRMLCAGYL 394 Query: 197 SKDQAPCKGDSGGPLVCGKGRV--LAGVLSFSSRVCTDIFKPPVATAVAPYVSWI 249 C+GDSGGPLVC G L GV+S+ R C + P V VA ++ WI Sbjct: 395 DGRADACQGDSGGPLVCPDGDTWRLVGVVSW-GRGCAEPNHPGVYAKVAEFLDWI 448 >gi|11496281 kallikrein 13 precursor [Homo sapiens] Length = 277 Score = 134 bits (338), Expect = 6e-32 Identities = 92/261 (35%), Positives = 137/261 (52%), Gaps = 22/261 (8%) Query: 5 VSSLLVLALGALSVGSSF-----GTQ--IIGGREVIPHSRPYMASLQRNGSHLCGGVLVH 57 ++SL + G +S SS GT + GG PHS+P+ A+L G LCGGVLVH Sbjct: 8 IASLTLALSGGVSQESSKVLNTNGTSGFLPGGYTCFPHSQPWQAALLVQGRLLCGGVLVH 67 Query: 58 PKWVLTAAHCLAQRMAQLRLVLGLHTL---DSPGLTFHIKAAIQHPRYKPVPA---LEND 111 PKWVLTAAHCL + L++ LG H L ++ + +I HP Y+ P ++D Sbjct: 68 PKWVLTAAHCLKE---GLKVYLGKHALGRVEAGEQVREVVHSIPHPEYRRSPTHLNHDHD 124 Query: 112 LALLQLDGKVKPSRTIRPLALPSKRQVVAAGTRCSMAGWGLTHQGG-RLSRVLRELDLQV 170 + LL+L V+ + I+ L L S + GT C ++GWG T + L+ ++Q+ Sbjct: 125 IMLLELQSPVQLTGYIQTLPL-SHNNRLTPGTTCRVSGWGTTTSPQVNYPKTLQCANIQL 183 Query: 171 LDTRMCNNSRFWNGSLSPSMVCLAADSKDQAPCKGDSGGPLVCGKGRVLAGVLSFSSRVC 230 C + + G ++ +M+C + C+GDSGGPLVC R L G++S+ C Sbjct: 184 RSDEECR--QVYPGKITDNMLCAGTKEGGKDSCEGDSGGPLVC--NRTLYGIVSWGDFPC 239 Query: 231 TDIFKPPVATAVAPYVSWIRK 251 +P V T V+ YV WIR+ Sbjct: 240 GQPDRPGVYTRVSRYVLWIRE 260 >gi|29244926 corin [Homo sapiens] Length = 1042 Score = 134 bits (337), Expect = 8e-32 Identities = 83/236 (35%), Positives = 130/236 (55%), Gaps = 13/236 (5%) Query: 25 QIIGGREVIPHSRPYMASLQRNGS-HLCGGVLVHPKWVLTAAHCLAQR--MAQLRLVLGL 81 +I+GGR P P+ SLQ S H+CG VL+ KWVLT AHC R A ++VLG+ Sbjct: 801 RILGGRTSRPGRWPWQCSLQSEPSGHICGCVLIAKKWVLTVAHCFEGRENAAVWKVVLGI 860 Query: 82 HTLDSPGL---TFHIKAAIQHPRYKPVPALENDLALLQLDGKVKPSRTIRPLALPSKRQV 138 + LD P + T +K I HPRY ++ D+++++L + + +RP+ LP+ Q Sbjct: 861 NNLDHPSVFMQTRFVKTIILHPRYSRA-VVDYDISIVELSEDISETGYVRPVCLPNPEQW 919 Query: 139 VAAGTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNSRFWNGSLSPSMVCLAADSK 198 + T C + GWG H G ++ L+E +++++ C S F +++ M+C +S Sbjct: 920 LEPDTYCYITGWG--HMGNKMPFKLQEGEVRIISLEHC-QSYFDMKTITTRMICAGYESG 976 Query: 199 DQAPCKGDSGGPLVCGK--GR-VLAGVLSFSSRVCTDIFKPPVATAVAPYVSWIRK 251 C GDSGGPLVC K GR L G+ S+ S + + P V + V+ +V WI++ Sbjct: 977 TVDSCMGDSGGPLVCEKPGGRWTLFGLTSWGSVCFSKVLGPGVYSNVSYFVEWIKR 1032 >gi|33695155 hepsin [Homo sapiens] Length = 417 Score = 134 bits (336), Expect = 1e-31 Identities = 81/240 (33%), Positives = 124/240 (51%), Gaps = 16/240 (6%) Query: 25 QIIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKWVLTAAHCLAQR---MAQLRLVLGL 81 +I+GGR+ P+ SL+ +G+HLCGG L+ WVLTAAHC +R +++ R+ G Sbjct: 162 RIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGA 221 Query: 82 HTLDSP-GLTFHIKAAIQHPRYKPV--PALE---NDLALLQLDGKVKPSRTIRPLALPSK 135 SP GL ++A + H Y P P E ND+AL+ L + + I+P+ LP+ Sbjct: 222 VAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPAA 281 Query: 136 RQVVAAGTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNSRFWNGSLSPSMVCLAA 195 Q + G C++ GWG T G+ + VL+E + ++ +CN + F+ + P M C Sbjct: 282 GQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAGY 341 Query: 196 DSKDQAPCKGDSGGPLVCGKGRV------LAGVLSFSSRVCTDIFKPPVATAVAPYVSWI 249 C+GDSGGP VC L G++S+ + C KP V T V+ + WI Sbjct: 342 PEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTG-CALAQKPGVYTKVSDFREWI 400 >gi|4504481 hepsin [Homo sapiens] Length = 417 Score = 134 bits (336), Expect = 1e-31 Identities = 81/240 (33%), Positives = 124/240 (51%), Gaps = 16/240 (6%) Query: 25 QIIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKWVLTAAHCLAQR---MAQLRLVLGL 81 +I+GGR+ P+ SL+ +G+HLCGG L+ WVLTAAHC +R +++ R+ G Sbjct: 162 RIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGA 221 Query: 82 HTLDSP-GLTFHIKAAIQHPRYKPV--PALE---NDLALLQLDGKVKPSRTIRPLALPSK 135 SP GL ++A + H Y P P E ND+AL+ L + + I+P+ LP+ Sbjct: 222 VAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPAA 281 Query: 136 RQVVAAGTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNSRFWNGSLSPSMVCLAA 195 Q + G C++ GWG T G+ + VL+E + ++ +CN + F+ + P M C Sbjct: 282 GQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAGY 341 Query: 196 DSKDQAPCKGDSGGPLVCGKGRV------LAGVLSFSSRVCTDIFKPPVATAVAPYVSWI 249 C+GDSGGP VC L G++S+ + C KP V T V+ + WI Sbjct: 342 PEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTG-CALAQKPGVYTKVSDFREWI 400 >gi|4505881 plasminogen [Homo sapiens] Length = 810 Score = 132 bits (332), Expect = 3e-31 Identities = 87/233 (37%), Positives = 125/233 (53%), Gaps = 11/233 (4%) Query: 25 QIIGGREVIPHSRPYMASLQ-RNGSHLCGGVLVHPKWVLTAAHCLAQ--RMAQLRLVLGL 81 +++GG PHS P+ SL+ R G H CGG L+ P+WVLTAAHCL + R + +++LG Sbjct: 580 RVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILGA 639 Query: 82 HTLDSPGLTFHIKAAIQHPRYKPVPALENDLALLQLDGKVKPSRTIRPLALPSKRQVVAA 141 H L H++ I+ R P D+ALL+L + + P LPS VVA Sbjct: 640 H--QEVNLEPHVQE-IEVSRLFLEPT-RKDIALLKLSSPAVITDKVIPACLPSPNYVVAD 695 Query: 142 GTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNSRFWNGSLSPSMVCLAADSKDQA 201 T C + GWG T QG + +L+E L V++ ++CN F NG + + +C + Sbjct: 696 RTECFITGWGET-QGTFGAGLLKEAQLPVIENKVCNRYEFLNGRVQSTELCAGHLAGGTD 754 Query: 202 PCKGDSGGPLVCGK--GRVLAGVLSFSSRVCTDIFKPPVATAVAPYVSWIRKV 252 C+GDSGGPLVC + +L GV S+ C KP V V+ +V+WI V Sbjct: 755 SCQGDSGGPLVCFEKDKYILQGVTSWGLG-CARPNKPGVYVRVSRFVTWIEGV 806 >gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens] Length = 260 Score = 130 bits (328), Expect = 9e-31 Identities = 87/255 (34%), Positives = 130/255 (50%), Gaps = 18/255 (7%) Query: 8 LLVLALGALSVGSSFGTQ--IIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKWVLTAA 65 + +L LG G S + ++GG E PHS+P+ A+L + LCGGVLV WVLTAA Sbjct: 13 MFLLLLGGAWAGHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAA 72 Query: 66 HCLAQRMAQLRLVLGLHTL---DSPGLTFHIKAAIQHPRY--KPVPALENDLALLQLDGK 120 HC + + + LG H+L D P + +I HP Y V +DL LLQL + Sbjct: 73 HC---KKPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQ 129 Query: 121 VKPSRTIRPLALPSKRQVVAAGTRCSMAGWG-LTHQGGRLSRVLRELDLQVLDTRMCNNS 179 ++P++L G +C+++GWG +T L ++++ + C ++ Sbjct: 130 ASLGSKVKPISLAD--HCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDA 187 Query: 180 RFWNGSLSPSMVCLAADSKDQAPCKGDSGGPLVCGKGRVLAGVLSFSSRVCTDIFKPPVA 239 + G ++ MVC A SK C+GDSGGPLVC L G+ S+ S C KP V Sbjct: 188 --YPGQITDGMVC-AGSSKGADTCQGDSGGPLVC--DGALQGITSWGSDPCGRSDKPGVY 242 Query: 240 TAVAPYVSWIRKVTG 254 T + Y+ WI+K+ G Sbjct: 243 TNICRYLDWIKKIIG 257 >gi|58331209 chymotrypsin-like elastase family, member 1 [Homo sapiens] Length = 258 Score = 130 bits (326), Expect = 1e-30 Identities = 87/240 (36%), Positives = 129/240 (53%), Gaps = 15/240 (6%) Query: 25 QIIGGREVIPHSRPYMASLQ-RNGS---HLCGGVLVHPKWVLTAAHCLAQRMAQLRLVLG 80 +++GG E +S P SLQ R+G H CGG L+ WV+TAAHC+ + R+V G Sbjct: 18 RVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGGTLIRQNWVMTAAHCVDYQKT-FRVVAG 76 Query: 81 LHTL---DSPGLTFHIKAAIQHPRYKPVP-ALENDLALLQLDGKVKPSRTIRPLALPSKR 136 H L D ++ + HP + A D+ALL+L V + ++ LP + Sbjct: 77 DHNLSQNDGTEQYVSVQKIVVHPYWNSDNVAAGYDIALLRLAQSVTLNSYVQLGVLPQEG 136 Query: 137 QVVAAGTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNSRFWNGSLSPSMVCLAAD 196 ++A + C + GWG T G+L++ L++ L +D +C++S +W ++ +MVC D Sbjct: 137 AILANNSPCYITGWGKTKTNGQLAQTLQQAYLPSVDYAICSSSSYWGSTVKNTMVCAGGD 196 Query: 197 SKDQAPCKGDSGGPLVC---GKGRVLAGVLSF-SSRVCTDIFKPPVATAVAPYVSWIRKV 252 ++ C+GDSGGPL C GK V GV SF SSR C KP V T V+ Y+SWI V Sbjct: 197 GV-RSGCQGDSGGPLHCLVNGKYSV-HGVTSFVSSRGCNVSRKPTVFTQVSAYISWINNV 254 >gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo sapiens] Length = 529 Score = 129 bits (325), Expect = 2e-30 Identities = 74/252 (29%), Positives = 132/252 (52%), Gaps = 10/252 (3%) Query: 5 VSSLLVLALGALSVGSSFGTQIIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKWVLTA 64 V SL +A G +++ SS ++I+GG +P + P+ SL H+CGG ++ P+W++TA Sbjct: 273 VVSLRCIACG-VNLNSSRQSRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTA 331 Query: 65 AHCLAQRMAQ---LRLVLGL--HTLDSPGLTFHIKAAIQHPRYKPVPALENDLALLQLDG 119 AHC+ + + G+ + G + ++ I HP Y ND+AL++L Sbjct: 332 AHCVEKPLNNPWHWTAFAGILRQSFMFYGAGYQVEKVISHPNYDS-KTKNNDIALMKLQK 390 Query: 120 KVKPSRTIRPLALPSKRQVVAAGTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNS 179 + + ++P+ LP+ ++ C ++GWG T + G+ S VL + +++T+ CN+ Sbjct: 391 PLTFNDLVKPVCLPNPGMMLQPEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSR 450 Query: 180 RFWNGSLSPSMVCLAADSKDQAPCKGDSGGPLVCGKGRV--LAGVLSFSSRVCTDIFKPP 237 ++ ++P+M+C + C+GDSGGPLV K + L G S+ S C ++P Sbjct: 451 YVYDNLITPAMICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSG-CAKAYRPG 509 Query: 238 VATAVAPYVSWI 249 V V + WI Sbjct: 510 VYGNVMVFTDWI 521 >gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo sapiens] Length = 492 Score = 129 bits (325), Expect = 2e-30 Identities = 74/252 (29%), Positives = 132/252 (52%), Gaps = 10/252 (3%) Query: 5 VSSLLVLALGALSVGSSFGTQIIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKWVLTA 64 V SL +A G +++ SS ++I+GG +P + P+ SL H+CGG ++ P+W++TA Sbjct: 236 VVSLRCIACG-VNLNSSRQSRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTA 294 Query: 65 AHCLAQRMAQ---LRLVLGL--HTLDSPGLTFHIKAAIQHPRYKPVPALENDLALLQLDG 119 AHC+ + + G+ + G + ++ I HP Y ND+AL++L Sbjct: 295 AHCVEKPLNNPWHWTAFAGILRQSFMFYGAGYQVEKVISHPNYDS-KTKNNDIALMKLQK 353 Query: 120 KVKPSRTIRPLALPSKRQVVAAGTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNS 179 + + ++P+ LP+ ++ C ++GWG T + G+ S VL + +++T+ CN+ Sbjct: 354 PLTFNDLVKPVCLPNPGMMLQPEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSR 413 Query: 180 RFWNGSLSPSMVCLAADSKDQAPCKGDSGGPLVCGKGRV--LAGVLSFSSRVCTDIFKPP 237 ++ ++P+M+C + C+GDSGGPLV K + L G S+ S C ++P Sbjct: 414 YVYDNLITPAMICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSG-CAKAYRPG 472 Query: 238 VATAVAPYVSWI 249 V V + WI Sbjct: 473 VYGNVMVFTDWI 484 >gi|11342670 azurocidin 1 preproprotein [Homo sapiens] Length = 251 Score = 129 bits (323), Expect = 3e-30 Identities = 92/250 (36%), Positives = 123/250 (49%), Gaps = 21/250 (8%) Query: 5 VSSLLVLALGALSVGSSFGTQIIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKWVLTA 64 V +LL L + GSS I+GGR+ P P++AS+Q G H CGG L+H ++V+TA Sbjct: 6 VLALLAGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTA 65 Query: 65 AHCL-AQRMAQLRLVLGLHTLD----SPGLTFHIKAAIQHPRYKPVPALENDLALLQLDG 119 A C +Q +VLG + L TF I + ++ Y P L NDL LLQLD Sbjct: 66 ASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENG-YDPQQNL-NDLMLLQLDR 123 Query: 120 KVKPSRTIRPLALPSKRQVVAAGTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNS 179 + + ++ L LP + V AGTRC +AGWG GGRLSR R +++ V C Sbjct: 124 EANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCR-- 181 Query: 180 RFWNGSLSPSMVCLAADSKDQAPCKGDSGGPLVCGKGRVLAGVLSFSSRVCTDIFKPPVA 239 P+ VC ++ C GD G PLVC + GV SFS C P Sbjct: 182 --------PNNVCTGVLTRRGGICNGDGGTPLVC--EGLAHGVASFSLGPCGR--GPDFF 229 Query: 240 TAVAPYVSWI 249 T VA + WI Sbjct: 230 TRVALFRDWI 239 >gi|21464127 kallikrein 8 isoform 2 [Homo sapiens] Length = 305 Score = 129 bits (323), Expect = 3e-30 Identities = 82/236 (34%), Positives = 123/236 (52%), Gaps = 16/236 (6%) Query: 25 QIIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKWVLTAAHCLAQRMAQLRLVLGLHTL 84 +++GG E PHS+P+ A+L + LCGGVLV WVLTAAHC + + + LG H+L Sbjct: 77 KVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHC---KKPKYTVRLGDHSL 133 Query: 85 ---DSPGLTFHIKAAIQHPRY--KPVPALENDLALLQLDGKVKPSRTIRPLALPSKRQVV 139 D P + +I HP Y V +DL LLQL + ++P++L Sbjct: 134 QNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLAD--HCT 191 Query: 140 AAGTRCSMAGWG-LTHQGGRLSRVLRELDLQVLDTRMCNNSRFWNGSLSPSMVCLAADSK 198 G +C+++GWG +T L ++++ + C ++ + G ++ MVC A SK Sbjct: 192 QPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDA--YPGQITDGMVC-AGSSK 248 Query: 199 DQAPCKGDSGGPLVCGKGRVLAGVLSFSSRVCTDIFKPPVATAVAPYVSWIRKVTG 254 C+GDSGGPLVC L G+ S+ S C KP V T + Y+ WI+K+ G Sbjct: 249 GADTCQGDSGGPLVC--DGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKIIG 302 >gi|23957702 transmembrane protease, serine 6 [Homo sapiens] Length = 811 Score = 129 bits (323), Expect = 3e-30 Identities = 85/239 (35%), Positives = 129/239 (53%), Gaps = 14/239 (5%) Query: 24 TQIIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKWVLTAAHCLAQ-RMAQLRL---VL 79 ++I+GG P+ ASLQ G H+CGG L+ +WV+TAAHC + MA L L Sbjct: 575 SRIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHCFQEDSMASTVLWTVFL 634 Query: 80 GLHTLDS--PG-LTFHIKAAIQHPRYKPVPALENDLALLQLDGKVKPSRTIRPLALPSKR 136 G +S PG ++F + + HP Y + + D+ALLQLD V S +RP+ LP++ Sbjct: 635 GKVWQNSRWPGEVSFKVSRLLLHP-YHEEDSHDYDVALLQLDHPVVRSAAVRPVCLPARS 693 Query: 137 QVVAAGTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNSRFWNGSLSPSMVCLAAD 196 G C + GWG +GG +S L+++D+Q++ +C S + ++P M+C Sbjct: 694 HFFEPGLHCWITGWGALREGGPISNALQKVDVQLIPQDLC--SEVYRYQVTPRMLCAGYR 751 Query: 197 SKDQAPCKGDSGGPLVCG--KGR-VLAGVLSFSSRVCTDIFKPPVATAVAPYVSWIRKV 252 + C+GDSGGPLVC GR LAG++S+ C V T + +SWI++V Sbjct: 752 KGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLG-CGRPNYFGVYTRITGVISWIQQV 809 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.322 0.136 0.422 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,275,050 Number of Sequences: 37866 Number of extensions: 456655 Number of successful extensions: 1422 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 160 Number of HSP's successfully gapped in prelim test: 13 Number of HSP's that attempted gapping in prelim test: 880 Number of HSP's gapped (non-prelim): 191 length of query: 257 length of database: 18,247,518 effective HSP length: 100 effective length of query: 157 effective length of database: 14,460,918 effective search space: 2270364126 effective search space used: 2270364126 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.