Guide to the Human Genome
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Name: ELANE Sequence: fasta or formatted (267aa) NCBI GI: 4503549
Description:

neutrophil elastase preproprotein

Referenced in:

Neutrophils, Eosinophils, and Basophils
Serine Proteases

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine            10.5         28           2
 C cysteine            4.1         11           1
 D aspartate           3.0          8           1
 E glutamate           1.9          5           1
 F phenylalanine       3.7         10           1
 G glycine            10.1         27           2
 H histidine           2.6          7           1
 I isoleucine          4.5         12           2
 K lysine              0.0          0           0
 L leucine            11.2         30           3
 M methionine          1.5          4           1
 N asparagine          6.4         17           1
 P proline             5.6         15           1
 Q glutamine           4.5         12           1
 R arginine            9.0         24           2
 S serine              5.6         15           1
 T threonine           3.4          9           1
 V valine             10.5         28           2
 W tryptophan          1.1          3           1
 Y tyrosine            0.7          2           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   neutrophil elastase preproprotein 
PRTN3                 0.474   myeloblastin 
AZU1                  0.335   azurocidin 1 preproprotein 
PRSSL1                0.254   protease, serine-like 1 
CELA1                 0.220   chymotrypsin-like elastase family, member 1 
CTSG                  0.216   cathepsin G preproprotein 
GZMM                  0.216   granzyme M precursor 
GZMA                  0.212   granzyme A precursor 
CFD                   0.208   complement factor D preproprotein 
GZMB                  0.193   granzyme B precursor 
KLK15                 0.193   kallikrein-related peptidase 15 isoform 4 preproprot...
CELA2A                0.191   elastase 2A preproprotein 
CTRC                  0.183   chymotrypsin C preproprotein 
GZMH                  0.183   granzyme H 
PLG                   0.183   plasminogen 
LPA                   0.179   lipoprotein Lp(a) precursor 
CELA3B                0.177   elastase 3B, pancreatic preproprotein 
CELA3A                0.177   elastase 3A, pancreatic preproprotein 
KLK4                  0.177   kallikrein-related peptidase 4 preproprotein 
CELA2B                0.173   elastase 2B preproprotein 
CMA1                  0.171   chymase 1, mast cell preproprotein 
OVCH1                 0.171   ovochymase 1 
KLK3                  0.170   prostate specific antigen isoform 1 preproprotein [Ho...
GZMK                  0.170   granzyme K precursor 
PRSS1                 0.154   protease, serine, 1 preproprotein 
TMPRSS5               0.154   transmembrane protease, serine 5 
PRSS3                 0.152   mesotrypsin isoform 1 preproprotein 
PRSS3                 0.152   mesotrypsin isoform 2 preproprotein 
PRSS36                0.150   protease, serine, 36 
CTRL                  0.150   chymotrypsin-like 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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