Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 4826998
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4826998 splicing factor proline/glutamine rich
(polypyrimidine tract binding protein associated) [Homo sapiens]
(707 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 1500 0.0
gi|109240550 paraspeckle protein 1 [Homo sapiens] 536 e-152
gi|224028246 non-POU domain containing, octamer-binding isoform ... 515 e-146
gi|224028244 non-POU domain containing, octamer-binding isoform ... 515 e-146
gi|34932414 non-POU domain containing, octamer-binding isoform 1... 515 e-146
gi|224028248 non-POU domain containing, octamer-binding isoform ... 444 e-124
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 139 7e-33
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 138 2e-32
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H... 131 2e-30
gi|160707881 formin 2 [Homo sapiens] 122 1e-27
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 116 8e-26
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 116 8e-26
gi|163965366 nascent polypeptide-associated complex alpha subuni... 111 2e-24
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 110 6e-24
gi|19924099 synapsin I isoform Ia [Homo sapiens] 110 6e-24
gi|19924097 synapsin I isoform Ib [Homo sapiens] 110 6e-24
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 109 8e-24
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 109 8e-24
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 109 1e-23
gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3 ... 107 3e-23
gi|150417989 cyclin K isoform 1 [Homo sapiens] 105 1e-22
gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] 104 2e-22
gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho... 104 2e-22
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens] 104 2e-22
gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2 ... 104 3e-22
gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1 [... 104 3e-22
gi|18959210 WIRE protein [Homo sapiens] 103 4e-22
gi|119829187 alpha 1 type XVII collagen [Homo sapiens] 100 4e-21
gi|150170670 piccolo isoform 2 [Homo sapiens] 100 6e-21
gi|150378539 piccolo isoform 1 [Homo sapiens] 100 6e-21
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 1500 bits (3883), Expect = 0.0
Identities = 707/707 (100%), Positives = 707/707 (100%)
Query: 1 MSRDRFRSRGGGGGGFHRRGGGGGRGGLHDFRSPPPGMGLNQNRGPMGPGPGQSGPKPPI 60
MSRDRFRSRGGGGGGFHRRGGGGGRGGLHDFRSPPPGMGLNQNRGPMGPGPGQSGPKPPI
Sbjct: 1 MSRDRFRSRGGGGGGFHRRGGGGGRGGLHDFRSPPPGMGLNQNRGPMGPGPGQSGPKPPI 60
Query: 61 PPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPG 120
PPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPG
Sbjct: 61 PPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPG 120
Query: 121 VGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQ 180
VGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQ
Sbjct: 121 VGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQ 180
Query: 181 AGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGGGE 240
AGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGGGE
Sbjct: 181 AGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGGGE 240
Query: 241 PRGGRQHHPPYHQQHHQGPPPGGPGGRSEEKISDSEGFKANLSLLRRPGEKTYTQRCRLF 300
PRGGRQHHPPYHQQHHQGPPPGGPGGRSEEKISDSEGFKANLSLLRRPGEKTYTQRCRLF
Sbjct: 241 PRGGRQHHPPYHQQHHQGPPPGGPGGRSEEKISDSEGFKANLSLLRRPGEKTYTQRCRLF 300
Query: 301 VGNLPADITEDEFKRLFAKYGEPGEVFINKGKGFGFIKLESRALAEIAKAELDDTPMRGR 360
VGNLPADITEDEFKRLFAKYGEPGEVFINKGKGFGFIKLESRALAEIAKAELDDTPMRGR
Sbjct: 301 VGNLPADITEDEFKRLFAKYGEPGEVFINKGKGFGFIKLESRALAEIAKAELDDTPMRGR 360
Query: 361 QLRVRFATHAAALSVRNLSPYVSNELLEEAFSQFGPIERAVVIVDDRGRSTGKGIVEFAS 420
QLRVRFATHAAALSVRNLSPYVSNELLEEAFSQFGPIERAVVIVDDRGRSTGKGIVEFAS
Sbjct: 361 QLRVRFATHAAALSVRNLSPYVSNELLEEAFSQFGPIERAVVIVDDRGRSTGKGIVEFAS 420
Query: 421 KPAARKAFERCSEGVFLLTTTPRPVIVEPLEQLDDEDGLPEKLAQKNPMYQKERETPPRF 480
KPAARKAFERCSEGVFLLTTTPRPVIVEPLEQLDDEDGLPEKLAQKNPMYQKERETPPRF
Sbjct: 421 KPAARKAFERCSEGVFLLTTTPRPVIVEPLEQLDDEDGLPEKLAQKNPMYQKERETPPRF 480
Query: 481 AQHGTFEYEYSQRWKSLDEMEKQQREQVEKNMKDAKDKLESEMEDAYHEHQANLLRQDLM 540
AQHGTFEYEYSQRWKSLDEMEKQQREQVEKNMKDAKDKLESEMEDAYHEHQANLLRQDLM
Sbjct: 481 AQHGTFEYEYSQRWKSLDEMEKQQREQVEKNMKDAKDKLESEMEDAYHEHQANLLRQDLM 540
Query: 541 RRQEELRRMEELHNQEMQKRKEMQLRQEEERRRREEEMMIRQREMEEQMRRQREESYSRM 600
RRQEELRRMEELHNQEMQKRKEMQLRQEEERRRREEEMMIRQREMEEQMRRQREESYSRM
Sbjct: 541 RRQEELRRMEELHNQEMQKRKEMQLRQEEERRRREEEMMIRQREMEEQMRRQREESYSRM 600
Query: 601 GYMDPRERDMRMGGGGAMNMGDPYGSGGQKFPPLGGGGGIGYEANPGVPPATMSGSMMGS 660
GYMDPRERDMRMGGGGAMNMGDPYGSGGQKFPPLGGGGGIGYEANPGVPPATMSGSMMGS
Sbjct: 601 GYMDPRERDMRMGGGGAMNMGDPYGSGGQKFPPLGGGGGIGYEANPGVPPATMSGSMMGS 660
Query: 661 DMRTERFGQGGAGPVGGQGPRGMGPGTPAGYGRGREEYEGPNKKPRF 707
DMRTERFGQGGAGPVGGQGPRGMGPGTPAGYGRGREEYEGPNKKPRF
Sbjct: 661 DMRTERFGQGGAGPVGGQGPRGMGPGTPAGYGRGREEYEGPNKKPRF 707
>gi|109240550 paraspeckle protein 1 [Homo sapiens]
Length = 523
Score = 536 bits (1381), Expect = e-152
Identities = 291/487 (59%), Positives = 350/487 (71%), Gaps = 49/487 (10%)
Query: 259 PPPGGPGGRSEEKISDSEGFKANLSLLRRPGEKTYTQRCRLFVGNLPADITEDEFKRLFA 318
P P P +E++ GF ++ +PGEKTYTQRCRLFVGNLP DITE++FKRLF
Sbjct: 48 PAPAPPEDHPDEEM----GFTIDIKSFLKPGEKTYTQRCRLFVGNLPTDITEEDFKRLFE 103
Query: 319 KYGEPGEVFINKGKGFGFIKLESRALAEIAKAELDDTPMRGRQLRVRFATHAAALSVRNL 378
+YGEP EVFIN+ +GFGFI+LESR LAEIAKAELD T ++ R LR+RFATH AAL+V+NL
Sbjct: 104 RYGEPSEVFINRDRGFGFIRLESRTLAEIAKAELDGTILKSRPLRIRFATHGAALTVKNL 163
Query: 379 SPYVSNELLEEAFSQFGPIERAVVIVDDRGRSTGKGIVEFASKPAARKAFERCSEGVFLL 438
SP VSNELLE+AFSQFGP+E+AVV+VDDRGR+TGKG VEFA+KP ARKA ERC +G FLL
Sbjct: 164 SPVVSNELLEQAFSQFGPVEKAVVVVDDRGRATGKGFVEFAAKPPARKALERCGDGAFLL 223
Query: 439 TTTPRPVIVEPLEQLDDEDGLPEKLAQKNPMYQKERETPPRFAQHGTFEYEYSQRWKSLD 498
TTTPRPVIVEP+EQ DDEDGLPEKL QK Y KERE PPRFAQ GTFE+EY+ RWK+LD
Sbjct: 224 TTTPRPVIVEPMEQFDDEDGLPEKLMQKTQQYHKEREQPPRFAQPGTFEFEYASRWKALD 283
Query: 499 EMEKQQREQVEKNMKDAKDKLESEMEDAYHEHQANLLRQDLMRRQEELRRMEELHNQEMQ 558
EMEKQQREQV++N+++AK+KLE+EME A HEHQ L+RQDLMRRQEELRR+EEL NQE+Q
Sbjct: 284 EMEKQQREQVDRNIREAKEKLEAEMEAARHEHQLMLMRQDLMRRQEELRRLEELRNQELQ 343
Query: 559 KRKEMQLRQEEERRRREEEMMIRQREMEEQMRRQREESYSRMGYMDPRERDMRMGG---G 615
KRK++QLR EEE RRREEE MIR RE EE +RRQ+E + YM+ RE++MRMG
Sbjct: 344 KRKQIQLRHEEEHRRREEE-MIRHREQEE-LRRQQEG--FKPNYMENREQEMRMGDMGPR 399
Query: 616 GAMNMGD---PYGSGGQ----------------KFPPLGGGGGIGYE--ANPGVPPATMS 654
GA+NMGD P +G Q PP+G G +G E AN G P +
Sbjct: 400 GAINMGDAFSPAPAGNQGPPPMMGMNMNNRATIPGPPMGPGPAMGPEGAANMGTPMMPDN 459
Query: 655 G------------SMMGSDMRTERFGQGGAGPVGGQGPRGMGPGTPAGYGRGRE--EYEG 700
G S MGS M + + P+ G GP GPG G+GRG + +EG
Sbjct: 460 GAVHNDRFPQGPPSQMGSPMGSRTGSETPQAPMSGVGPVSGGPG---GFGRGSQGGNFEG 516
Query: 701 PNKKPRF 707
PNK+ R+
Sbjct: 517 PNKRRRY 523
Score = 42.4 bits (98), Expect = 0.001
Identities = 33/100 (33%), Positives = 35/100 (35%), Gaps = 14/100 (14%)
Query: 177 TPPQAGGPPPPP---------AAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTP 227
+P AG PPP A +PGP GP GP G P P G P
Sbjct: 409 SPAPAGNQGPPPMMGMNMNNRATIPGPPMGPGPAMGPEGAANMGTPMMPDNGAVHNDRFP 468
Query: 228 GGHPKPPHRGGGEPRGGRQ-HHPPYHQQHHQGPPPGGPGG 266
G P G P G R P GP GGPGG
Sbjct: 469 QGPPSQM----GSPMGSRTGSETPQAPMSGVGPVSGGPGG 504
Score = 38.5 bits (88), Expect = 0.022
Identities = 43/172 (25%), Positives = 59/172 (34%), Gaps = 31/172 (18%)
Query: 94 HQQQQPPPPPQDSSKPVVAQ-----------GPGPAPGVGSA---PPASSSAPPATPPTS 139
H++Q+ Q+ KP + GP A +G A PA + PP +
Sbjct: 366 HREQEELRRQQEGFKPNYMENREQEMRMGDMGPRGAINMGDAFSPAPAGNQGPPPMMGMN 425
Query: 140 GAPPGSGPGPTPTPPPAVTSAPPGAP---PPTPPSSGVPTTPPQAGGPPPPPAAVPGPGP 196
+ PGP P PA+ P GA P P +G GPP
Sbjct: 426 MNNRATIPGPPMGPGPAM--GPEGAANMGTPMMPDNGAVHNDRFPQGPPS---------- 473
Query: 197 GPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHH 248
+ G G G + P P G GP PGG + G E R+ +
Sbjct: 474 --QMGSPMGSRTGSETPQAPMSGVGPVSGGPGGFGRGSQGGNFEGPNKRRRY 523
Score = 37.0 bits (84), Expect = 0.063
Identities = 31/117 (26%), Positives = 40/117 (34%), Gaps = 24/117 (20%)
Query: 32 RSPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHP 91
+ PPP MG+N N PGP P P P P P P +
Sbjct: 416 QGPPPMMGMNMNNRATIPGP----PMGPGPAMGPEGAANMGTPMM-----------PDNG 460
Query: 92 QPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPG 148
H + P PP P+ ++ GS P + + P SG P G G G
Sbjct: 461 AVHNDRFPQGPPSQMGSPMGSR-------TGSETPQAPMS--GVGPVSGGPGGFGRG 508
>gi|224028246 non-POU domain containing, octamer-binding isoform 1
[Homo sapiens]
Length = 471
Score = 515 bits (1327), Expect = e-146
Identities = 284/475 (59%), Positives = 346/475 (72%), Gaps = 27/475 (5%)
Query: 241 PRGGRQHH--PPYHQQHHQGPPPGGPGGRSEEKISDSEGFKANLSLLRRPGEKTYTQRCR 298
PR QHH +HQQ Q PPP ++ S +EG +L R+PGEKT+TQR R
Sbjct: 16 PRKHHQHHHQQQHHQQQQQQPPPPPIPANGQQASSQNEGLTIDLKNFRKPGEKTFTQRSR 75
Query: 299 LFVGNLPADITEDEFKRLFAKYGEPGEVFINKGKGFGFIKLESRALAEIAKAELDDTPMR 358
LFVGNLP DITE+E ++LF KYG+ GEVFI+K KGFGFI+LE+R LAEIAK ELD+ P+R
Sbjct: 76 LFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRTLAEIAKVELDNMPLR 135
Query: 359 GRQLRVRFATHAAALSVRNLSPYVSNELLEEAFSQFGPIERAVVIVDDRGRSTGKGIVEF 418
G+QLRVRFA H+A+L+VRNL YVSNELLEEAFS FG +ERAVVIVDDRGR +GKGIVEF
Sbjct: 136 GKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVIVDDRGRPSGKGIVEF 195
Query: 419 ASKPAARKAFERCSEGVFLLTTTPRPVIVEPLEQLDDEDGLPEKLAQKNPMYQKERETPP 478
+ KPAARKA +RCSEG FLLTT PRPV VEP++QLDDE+GLPEKL KN + KERE PP
Sbjct: 196 SGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEKLVIKNQQFHKEREQPP 255
Query: 479 RFAQHGTFEYEYSQRWKSLDEMEKQQREQVEKNMKDAKDKLESEMEDAYHEHQANLLRQD 538
RFAQ G+FEYEY+ RWK+L EMEKQQ++QV++N+K+A++KLE EME A HEHQ L+RQD
Sbjct: 256 RFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEMEAARHEHQVMLMRQD 315
Query: 539 LMRRQEELRRMEELHNQEMQKRKEMQLRQEEERRRREEEMMIRQREMEEQMRRQREESYS 598
LMRRQEELRRMEELHNQE+QKRK+++LRQEEERRRREEEM +R+ EE MRRQ+E
Sbjct: 316 LMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEM---RRQQEEMMRRQQEG--F 370
Query: 599 RMGYMDPRERDMRMGG---GGAMNMGDPYGSGGQKFPPLGGGGGIGYEANPGVPPATM-- 653
+ + D RE+++RMG GGAM + + G P+ G A PG PATM
Sbjct: 371 KGTFPDAREQEIRMGQMAMGGAMGINN---RGAMPPAPVPA----GTPAPPG--PATMMP 421
Query: 654 SGSMMGSDMRTERFGQGGAGPVGGQGPRGMGPGTPAGYGRGREEYE-GPNKKPRF 707
G++ + TERFGQ A + G G G GTP + R E PNK+ R+
Sbjct: 422 DGTLGLTPPTTERFGQ--AATMEGIGAIG---GTPPAFNRAAPGAEFAPNKRRRY 471
Score = 32.7 bits (73), Expect = 1.2
Identities = 21/64 (32%), Positives = 22/64 (34%), Gaps = 3/64 (4%)
Query: 142 PPGSGPGPTPTPPPAVTSAPPGA---PPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGP 198
PP P TP PP T P G PPT G T G P A PG
Sbjct: 402 PPAPVPAGTPAPPGPATMMPDGTLGLTPPTTERFGQAATMEGIGAIGGTPPAFNRAAPGA 461
Query: 199 KQGP 202
+ P
Sbjct: 462 EFAP 465
Score = 30.8 bits (68), Expect = 4.5
Identities = 22/62 (35%), Positives = 25/62 (40%), Gaps = 9/62 (14%)
Query: 112 AQGPGPAPGVGSAPPASSSAPP-----ATPPTSG----APPGSGPGPTPTPPPAVTSAPP 162
A P P P APP ++ P TPPT+ A G G PPA A P
Sbjct: 400 AMPPAPVPAGTPAPPGPATMMPDGTLGLTPPTTERFGQAATMEGIGAIGGTPPAFNRAAP 459
Query: 163 GA 164
GA
Sbjct: 460 GA 461
Score = 30.4 bits (67), Expect = 5.9
Identities = 14/25 (56%), Positives = 14/25 (56%), Gaps = 3/25 (12%)
Query: 82 PPPHQPPPHPQPH---QQQQPPPPP 103
P H H Q H QQQQPPPPP
Sbjct: 16 PRKHHQHHHQQQHHQQQQQQPPPPP 40
>gi|224028244 non-POU domain containing, octamer-binding isoform 1
[Homo sapiens]
Length = 471
Score = 515 bits (1327), Expect = e-146
Identities = 284/475 (59%), Positives = 346/475 (72%), Gaps = 27/475 (5%)
Query: 241 PRGGRQHH--PPYHQQHHQGPPPGGPGGRSEEKISDSEGFKANLSLLRRPGEKTYTQRCR 298
PR QHH +HQQ Q PPP ++ S +EG +L R+PGEKT+TQR R
Sbjct: 16 PRKHHQHHHQQQHHQQQQQQPPPPPIPANGQQASSQNEGLTIDLKNFRKPGEKTFTQRSR 75
Query: 299 LFVGNLPADITEDEFKRLFAKYGEPGEVFINKGKGFGFIKLESRALAEIAKAELDDTPMR 358
LFVGNLP DITE+E ++LF KYG+ GEVFI+K KGFGFI+LE+R LAEIAK ELD+ P+R
Sbjct: 76 LFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRTLAEIAKVELDNMPLR 135
Query: 359 GRQLRVRFATHAAALSVRNLSPYVSNELLEEAFSQFGPIERAVVIVDDRGRSTGKGIVEF 418
G+QLRVRFA H+A+L+VRNL YVSNELLEEAFS FG +ERAVVIVDDRGR +GKGIVEF
Sbjct: 136 GKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVIVDDRGRPSGKGIVEF 195
Query: 419 ASKPAARKAFERCSEGVFLLTTTPRPVIVEPLEQLDDEDGLPEKLAQKNPMYQKERETPP 478
+ KPAARKA +RCSEG FLLTT PRPV VEP++QLDDE+GLPEKL KN + KERE PP
Sbjct: 196 SGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEKLVIKNQQFHKEREQPP 255
Query: 479 RFAQHGTFEYEYSQRWKSLDEMEKQQREQVEKNMKDAKDKLESEMEDAYHEHQANLLRQD 538
RFAQ G+FEYEY+ RWK+L EMEKQQ++QV++N+K+A++KLE EME A HEHQ L+RQD
Sbjct: 256 RFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEMEAARHEHQVMLMRQD 315
Query: 539 LMRRQEELRRMEELHNQEMQKRKEMQLRQEEERRRREEEMMIRQREMEEQMRRQREESYS 598
LMRRQEELRRMEELHNQE+QKRK+++LRQEEERRRREEEM +R+ EE MRRQ+E
Sbjct: 316 LMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEM---RRQQEEMMRRQQEG--F 370
Query: 599 RMGYMDPRERDMRMGG---GGAMNMGDPYGSGGQKFPPLGGGGGIGYEANPGVPPATM-- 653
+ + D RE+++RMG GGAM + + G P+ G A PG PATM
Sbjct: 371 KGTFPDAREQEIRMGQMAMGGAMGINN---RGAMPPAPVPA----GTPAPPG--PATMMP 421
Query: 654 SGSMMGSDMRTERFGQGGAGPVGGQGPRGMGPGTPAGYGRGREEYE-GPNKKPRF 707
G++ + TERFGQ A + G G G GTP + R E PNK+ R+
Sbjct: 422 DGTLGLTPPTTERFGQ--AATMEGIGAIG---GTPPAFNRAAPGAEFAPNKRRRY 471
Score = 32.7 bits (73), Expect = 1.2
Identities = 21/64 (32%), Positives = 22/64 (34%), Gaps = 3/64 (4%)
Query: 142 PPGSGPGPTPTPPPAVTSAPPGA---PPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGP 198
PP P TP PP T P G PPT G T G P A PG
Sbjct: 402 PPAPVPAGTPAPPGPATMMPDGTLGLTPPTTERFGQAATMEGIGAIGGTPPAFNRAAPGA 461
Query: 199 KQGP 202
+ P
Sbjct: 462 EFAP 465
Score = 30.8 bits (68), Expect = 4.5
Identities = 22/62 (35%), Positives = 25/62 (40%), Gaps = 9/62 (14%)
Query: 112 AQGPGPAPGVGSAPPASSSAPP-----ATPPTSG----APPGSGPGPTPTPPPAVTSAPP 162
A P P P APP ++ P TPPT+ A G G PPA A P
Sbjct: 400 AMPPAPVPAGTPAPPGPATMMPDGTLGLTPPTTERFGQAATMEGIGAIGGTPPAFNRAAP 459
Query: 163 GA 164
GA
Sbjct: 460 GA 461
Score = 30.4 bits (67), Expect = 5.9
Identities = 14/25 (56%), Positives = 14/25 (56%), Gaps = 3/25 (12%)
Query: 82 PPPHQPPPHPQPH---QQQQPPPPP 103
P H H Q H QQQQPPPPP
Sbjct: 16 PRKHHQHHHQQQHHQQQQQQPPPPP 40
>gi|34932414 non-POU domain containing, octamer-binding isoform 1
[Homo sapiens]
Length = 471
Score = 515 bits (1327), Expect = e-146
Identities = 284/475 (59%), Positives = 346/475 (72%), Gaps = 27/475 (5%)
Query: 241 PRGGRQHH--PPYHQQHHQGPPPGGPGGRSEEKISDSEGFKANLSLLRRPGEKTYTQRCR 298
PR QHH +HQQ Q PPP ++ S +EG +L R+PGEKT+TQR R
Sbjct: 16 PRKHHQHHHQQQHHQQQQQQPPPPPIPANGQQASSQNEGLTIDLKNFRKPGEKTFTQRSR 75
Query: 299 LFVGNLPADITEDEFKRLFAKYGEPGEVFINKGKGFGFIKLESRALAEIAKAELDDTPMR 358
LFVGNLP DITE+E ++LF KYG+ GEVFI+K KGFGFI+LE+R LAEIAK ELD+ P+R
Sbjct: 76 LFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRTLAEIAKVELDNMPLR 135
Query: 359 GRQLRVRFATHAAALSVRNLSPYVSNELLEEAFSQFGPIERAVVIVDDRGRSTGKGIVEF 418
G+QLRVRFA H+A+L+VRNL YVSNELLEEAFS FG +ERAVVIVDDRGR +GKGIVEF
Sbjct: 136 GKQLRVRFACHSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVIVDDRGRPSGKGIVEF 195
Query: 419 ASKPAARKAFERCSEGVFLLTTTPRPVIVEPLEQLDDEDGLPEKLAQKNPMYQKERETPP 478
+ KPAARKA +RCSEG FLLTT PRPV VEP++QLDDE+GLPEKL KN + KERE PP
Sbjct: 196 SGKPAARKALDRCSEGSFLLTTFPRPVTVEPMDQLDDEEGLPEKLVIKNQQFHKEREQPP 255
Query: 479 RFAQHGTFEYEYSQRWKSLDEMEKQQREQVEKNMKDAKDKLESEMEDAYHEHQANLLRQD 538
RFAQ G+FEYEY+ RWK+L EMEKQQ++QV++N+K+A++KLE EME A HEHQ L+RQD
Sbjct: 256 RFAQPGSFEYEYAMRWKALIEMEKQQQDQVDRNIKEAREKLEMEMEAARHEHQVMLMRQD 315
Query: 539 LMRRQEELRRMEELHNQEMQKRKEMQLRQEEERRRREEEMMIRQREMEEQMRRQREESYS 598
LMRRQEELRRMEELHNQE+QKRK+++LRQEEERRRREEEM +R+ EE MRRQ+E
Sbjct: 316 LMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEM---RRQQEEMMRRQQEG--F 370
Query: 599 RMGYMDPRERDMRMGG---GGAMNMGDPYGSGGQKFPPLGGGGGIGYEANPGVPPATM-- 653
+ + D RE+++RMG GGAM + + G P+ G A PG PATM
Sbjct: 371 KGTFPDAREQEIRMGQMAMGGAMGINN---RGAMPPAPVPA----GTPAPPG--PATMMP 421
Query: 654 SGSMMGSDMRTERFGQGGAGPVGGQGPRGMGPGTPAGYGRGREEYE-GPNKKPRF 707
G++ + TERFGQ A + G G G GTP + R E PNK+ R+
Sbjct: 422 DGTLGLTPPTTERFGQ--AATMEGIGAIG---GTPPAFNRAAPGAEFAPNKRRRY 471
Score = 32.7 bits (73), Expect = 1.2
Identities = 21/64 (32%), Positives = 22/64 (34%), Gaps = 3/64 (4%)
Query: 142 PPGSGPGPTPTPPPAVTSAPPGA---PPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGP 198
PP P TP PP T P G PPT G T G P A PG
Sbjct: 402 PPAPVPAGTPAPPGPATMMPDGTLGLTPPTTERFGQAATMEGIGAIGGTPPAFNRAAPGA 461
Query: 199 KQGP 202
+ P
Sbjct: 462 EFAP 465
Score = 30.8 bits (68), Expect = 4.5
Identities = 22/62 (35%), Positives = 25/62 (40%), Gaps = 9/62 (14%)
Query: 112 AQGPGPAPGVGSAPPASSSAPP-----ATPPTSG----APPGSGPGPTPTPPPAVTSAPP 162
A P P P APP ++ P TPPT+ A G G PPA A P
Sbjct: 400 AMPPAPVPAGTPAPPGPATMMPDGTLGLTPPTTERFGQAATMEGIGAIGGTPPAFNRAAP 459
Query: 163 GA 164
GA
Sbjct: 460 GA 461
Score = 30.4 bits (67), Expect = 5.9
Identities = 14/25 (56%), Positives = 14/25 (56%), Gaps = 3/25 (12%)
Query: 82 PPPHQPPPHPQPH---QQQQPPPPP 103
P H H Q H QQQQPPPPP
Sbjct: 16 PRKHHQHHHQQQHHQQQQQQPPPPP 40
>gi|224028248 non-POU domain containing, octamer-binding isoform 2
[Homo sapiens]
Length = 382
Score = 444 bits (1141), Expect = e-124
Identities = 246/400 (61%), Positives = 300/400 (75%), Gaps = 25/400 (6%)
Query: 314 KRLFAKYGEPGEVFINKGKGFGFIKLESRALAEIAKAELDDTPMRGRQLRVRFATHAAAL 373
++LF KYG+ GEVFI+K KGFGFI+LE+R LAEIAK ELD+ P+RG+QLRVRFA H+A+L
Sbjct: 2 RKLFEKYGKAGEVFIHKDKGFGFIRLETRTLAEIAKVELDNMPLRGKQLRVRFACHSASL 61
Query: 374 SVRNLSPYVSNELLEEAFSQFGPIERAVVIVDDRGRSTGKGIVEFASKPAARKAFERCSE 433
+VRNL YVSNELLEEAFS FG +ERAVVIVDDRGR +GKGIVEF+ KPAARKA +RCSE
Sbjct: 62 TVRNLPQYVSNELLEEAFSVFGQVERAVVIVDDRGRPSGKGIVEFSGKPAARKALDRCSE 121
Query: 434 GVFLLTTTPRPVIVEPLEQLDDEDGLPEKLAQKNPMYQKERETPPRFAQHGTFEYEYSQR 493
G FLLTT PRPV VEP++QLDDE+GLPEKL KN + KERE PPRFAQ G+FEYEY+ R
Sbjct: 122 GSFLLTTFPRPVTVEPMDQLDDEEGLPEKLVIKNQQFHKEREQPPRFAQPGSFEYEYAMR 181
Query: 494 WKSLDEMEKQQREQVEKNMKDAKDKLESEMEDAYHEHQANLLRQDLMRRQEELRRMEELH 553
WK+L EMEKQQ++QV++N+K+A++KLE EME A HEHQ L+RQDLMRRQEELRRMEELH
Sbjct: 182 WKALIEMEKQQQDQVDRNIKEAREKLEMEMEAARHEHQVMLMRQDLMRRQEELRRMEELH 241
Query: 554 NQEMQKRKEMQLRQEEERRRREEEMMIRQREMEEQMRRQREESYSRMGYMDPRERDMRMG 613
NQE+QKRK+++LRQEEERRRREEEM +R+ EE MRRQ+E + + D RE+++RMG
Sbjct: 242 NQEVQKRKQLELRQEEERRRREEEM---RRQQEEMMRRQQEG--FKGTFPDAREQEIRMG 296
Query: 614 G---GGAMNMGDPYGSGGQKFPPLGGGGGIGYEANPGVPPATM--SGSMMGSDMRTERFG 668
GGAM + + G P+ G A PG PATM G++ + TERFG
Sbjct: 297 QMAMGGAMGINN---RGAMPPAPVPA----GTPAPPG--PATMMPDGTLGLTPPTTERFG 347
Query: 669 QGGAGPVGGQGPRGMGPGTPAGYGRGREEYE-GPNKKPRF 707
Q A + G G G GTP + R E PNK+ R+
Sbjct: 348 Q--AATMEGIGAIG---GTPPAFNRAAPGAEFAPNKRRRY 382
Score = 32.7 bits (73), Expect = 1.2
Identities = 21/64 (32%), Positives = 22/64 (34%), Gaps = 3/64 (4%)
Query: 142 PPGSGPGPTPTPPPAVTSAPPGA---PPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGP 198
PP P TP PP T P G PPT G T G P A PG
Sbjct: 313 PPAPVPAGTPAPPGPATMMPDGTLGLTPPTTERFGQAATMEGIGAIGGTPPAFNRAAPGA 372
Query: 199 KQGP 202
+ P
Sbjct: 373 EFAP 376
Score = 30.8 bits (68), Expect = 4.5
Identities = 22/62 (35%), Positives = 25/62 (40%), Gaps = 9/62 (14%)
Query: 112 AQGPGPAPGVGSAPPASSSAPP-----ATPPTSG----APPGSGPGPTPTPPPAVTSAPP 162
A P P P APP ++ P TPPT+ A G G PPA A P
Sbjct: 311 AMPPAPVPAGTPAPPGPATMMPDGTLGLTPPTTERFGQAATMEGIGAIGGTPPAFNRAAP 370
Query: 163 GA 164
GA
Sbjct: 371 GA 372
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 139 bits (351), Expect = 7e-33
Identities = 99/270 (36%), Positives = 118/270 (43%), Gaps = 49/270 (18%)
Query: 46 PMGPGPGQSGPKPPIPPPPPHQQQQQPP-----PQQPPPQQPPPHQPPPHPQPHQQQQPP 100
P GP P Q G KP PPPPP + Q PP PQ PPP P PP + + PP
Sbjct: 36 PQGPSP-QGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPP 94
Query: 101 -----PPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAP------------P 143
PPPQ ++P QGP P PG PP P PP G P P
Sbjct: 95 GKPQGPPPQGGNQP---QGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSP 151
Query: 144 GSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGP----PPPPAAVPGPGP-GP 198
S PG PPP + P G PPP G P PP GG PPPP GP P G
Sbjct: 152 RSPPGKPQGPPPQGGNQPQGPPPP----PGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGD 207
Query: 199 K----QGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGGGEPRG----GRQHHPP 250
K Q P PG P+G GG +P G P PG PP +GG +P+G G+ PP
Sbjct: 208 KSRSSQSP-PGKPQGPPPQGGNQPQGPP--PPPGKPQGPPPQGGNKPQGPPPPGKPQGPP 264
Query: 251 YH---QQHHQGPPPGGPGGRSEEKISDSEG 277
+ PPG P G +++ ++ +G
Sbjct: 265 AQGGSKSQSARSPPGKPQGPPQQEGNNPQG 294
Score = 130 bits (328), Expect = 3e-30
Identities = 97/274 (35%), Positives = 112/274 (40%), Gaps = 59/274 (21%)
Query: 35 PPGMGLNQNRGPMGPGPGQSGP--------------KPPIPPPPPHQQQQQPPPQQPPPQ 80
PP G N+ +GP PG Q P KP PPP Q Q PPP PQ
Sbjct: 60 PPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 119
Query: 81 QPPP---HQPPPHPQPHQQQQPP------------------PPPQDSSKPVVAQGPGPAP 119
PPP ++P P P + Q PP PPPQ ++P QGP P P
Sbjct: 120 GPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQP---QGPPPPP 176
Query: 120 GVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTS-APPGAPPPTPPSSGVPTTP 178
G PP P PP PPG GP P + +S +PPG P PP G
Sbjct: 177 GKPQGPPPQGGKKPQGPP----PPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGG----- 227
Query: 179 PQAGGPPPPPAAVPGPGP----GPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPP 234
Q GPPPPP GP P P+ P PG P+G GG K S PG PP
Sbjct: 228 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSK--SQSARSPPGKPQGPP 285
Query: 235 HRGGGEPRGGRQHHPPY--HQQHHQGPPPGGPGG 266
+ G P+G PP + Q Q PP G P G
Sbjct: 286 QQEGNNPQG---PPPPAGGNPQQPQAPPAGQPQG 316
Score = 129 bits (324), Expect = 9e-30
Identities = 99/263 (37%), Positives = 111/263 (42%), Gaps = 38/263 (14%)
Query: 32 RSPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPP--PQQPPP---HQ 86
+ PPP G Q P G Q P P P PP Q + P+ PP PQ PPP +Q
Sbjct: 48 QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQ 107
Query: 87 PP-PHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPP--ASSSAPPATPP--TSGA 141
P P P P + Q PPPQ ++P QGP P PG PP S P +PP G
Sbjct: 108 PQGPPPPPGKPQ--GPPPQGGNRP---QGP-PPPGKPQGPPPQGDKSRSPRSPPGKPQGP 161
Query: 142 PPGSGPGPT-PTPPPAVTSAPP---GAPPPTPPSSGVPTTPPQAG-------GPPPPPAA 190
PP G P P PPP PP G P PP G P PP G PP P
Sbjct: 162 PPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQG 221
Query: 191 VPGPGPGPKQG--PGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGGGE------PR 242
P G QG P PG P+G GG KP G P PG PP +GG + P
Sbjct: 222 PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP---PPGKPQGPPAQGGSKSQSARSPP 278
Query: 243 GGRQHHPPYHQQHHQGPPPGGPG 265
G Q P + QGPPP G
Sbjct: 279 GKPQGPPQQEGNNPQGPPPPAGG 301
Score = 129 bits (324), Expect = 9e-30
Identities = 99/264 (37%), Positives = 110/264 (41%), Gaps = 66/264 (25%)
Query: 32 RSP--PPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPP-----PQQPPPQQPPP 84
RSP PPG P GP P Q G +P PPPPP + Q PP PQ PPP P
Sbjct: 88 RSPRSPPGK-------PQGPPP-QGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQ 139
Query: 85 HQPPPHPQPHQQQQPP-----PPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTS 139
PP + + PP PPPQ ++P QGP P PG PP P PP
Sbjct: 140 GPPPQGDKSRSPRSPPGKPQGPPPQGGNQP---QGPPPPPGKPQGPPPQGGKKPQGPPPP 196
Query: 140 GAPPG------------SGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGG---- 183
G P G S PG PPP + P G PPP G P PP GG
Sbjct: 197 GKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPP----GKPQGPPPQGGNKPQ 252
Query: 184 PPPPPAAVPGPGPGPKQGPG--------PGGPKG-----GKMPGGPKP--GGGP--GLST 226
PPPP GP P QG PG P+G G P GP P GG P +
Sbjct: 253 GPPPPGKPQGP---PAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAP 309
Query: 227 PGGHPKPPHRGGGEPRGGRQHHPP 250
P G P+ P R P+GGR PP
Sbjct: 310 PAGQPQGPPR---PPQGGRPSRPP 330
Score = 108 bits (270), Expect = 2e-23
Identities = 79/202 (39%), Positives = 88/202 (43%), Gaps = 35/202 (17%)
Query: 32 RSP--PPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPP-----PQQPPPQQPPP 84
RSP PPG P GP P Q G +P PPPPP + Q PP PQ PPP P
Sbjct: 149 RSPRSPPGK-------PQGPPP-QGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQ 200
Query: 85 HQPPPHPQPHQQQQPP-----PPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTS 139
PP + Q PP PPPQ ++P QGP P PG PP P PP
Sbjct: 201 GPPPQGDKSRSSQSPPGKPQGPPPQGGNQP---QGPPPPPGKPQGPPPQGGNKPQGPP-- 255
Query: 140 GAPPGSGPGPTPTPPPAVTSA--PPGAP--PPTPPSSGVPTTPPQAGGPPPPPAAVPGPG 195
PPG GP SA PPG P PP + PP AGG P P A P
Sbjct: 256 --PPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPA-- 311
Query: 196 PGPKQGPGPGGPKGGKMPGGPK 217
G QGP P P+GG+ P+
Sbjct: 312 -GQPQGP-PRPPQGGRPSRPPQ 331
Score = 103 bits (256), Expect = 7e-22
Identities = 90/265 (33%), Positives = 106/265 (40%), Gaps = 56/265 (21%)
Query: 67 QQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPP---------PPPQDSSKPVVAQGPGP 117
Q + Q+ P + P PQ + Q P PPPQ +KP QGP P
Sbjct: 17 QNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKP---QGP-P 72
Query: 118 APGVGSAPP--ASSSAPPATPP--TSGAPPGSGPGPT-PTPPPAVTSAPP---GAPPPTP 169
PG PP S P +PP G PP G P P PPP PP G P P
Sbjct: 73 PPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGP 132
Query: 170 PSSGVPTTPPQAG--------------GPPPPPAAVP-GPGPGPKQGPGPGGPKGGKMPG 214
P G P PP G GPPP P GP P P + GP P+GGK P
Sbjct: 133 PPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP-PPQGGKKPQ 191
Query: 215 GPKPGGGP------------GLSTPGGHPKPPHRGGGEPRG-----GR-QHHPPYHQQHH 256
GP P G P S PG PP +GG +P+G G+ Q PP
Sbjct: 192 GPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP 251
Query: 257 QG-PPPGGPGGRSEEKISDSEGFKA 280
QG PPPG P G + S S+ ++
Sbjct: 252 QGPPPPGKPQGPPAQGGSKSQSARS 276
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 138 bits (348), Expect = 2e-32
Identities = 99/272 (36%), Positives = 116/272 (42%), Gaps = 44/272 (16%)
Query: 36 PGMGLNQNRGPMGPG------PGQSGPKPPIPPPPPHQQQQQPP-----PQQPPPQQPPP 84
P G N+ +GP P P Q G +P PPPPP + Q PP PQ PPP P
Sbjct: 40 PPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQ 99
Query: 85 HQPPPHPQPHQQQQPP-----PPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTS 139
PP + + PP PPPQ ++P QGP P PG PP P PP
Sbjct: 100 GPPPQGDKSRSPRSPPGKPQGPPPQGGNQP---QGPPPPPGKPQGPPPQGGNKPQGPPPP 156
Query: 140 GAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPK 199
G P GP P + +PPG P PP G Q GPPPPP GP P+
Sbjct: 157 GKP--QGPPPQGDNKSRSSRSPPGKPQGPPPQGG-----NQPQGPPPPPG--KPQGPPPQ 207
Query: 200 QGPGPGGPKGGKMPGGPKPGGG----PGLSTPGGHPKPPHRGGGEPRG-----GR-QHHP 249
G P GP P GP P G S PG PP +GG +P+G G+ Q P
Sbjct: 208 GGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP 267
Query: 250 PYHQQHHQGPPPGG------PGGRSEEKISDS 275
P QGPPP G P G S+ + S S
Sbjct: 268 PQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRS 299
Score = 138 bits (348), Expect = 2e-32
Identities = 99/251 (39%), Positives = 108/251 (43%), Gaps = 46/251 (18%)
Query: 32 RSP--PPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPP 89
RSP PPG P GP P Q G +P PPPPP + Q PP PQ PPP P
Sbjct: 109 RSPRSPPGK-------PQGPPP-QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQ 160
Query: 90 HPQPH------QQQQPP-----PPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPT 138
P P + PP PPPQ ++P QGP P PG PP P PP
Sbjct: 161 GPPPQGDNKSRSSRSPPGKPQGPPPQGGNQP---QGPPPPPGKPQGPPPQGGNKPQGPP- 216
Query: 139 SGAPPGSGPGPTPTPPPAVTSA--PPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGP 196
PPG GP P SA PPG P PP G Q GPPPPP GP
Sbjct: 217 ---PPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGG-----NQPQGPPPPPG--KPQGP 266
Query: 197 GPKQGPGPGGPKGGKMPGGPKPGGG----PGLSTPGGHPKPPHRGGGEPRGGRQHHPPYH 252
P+ G P GP P GP P GG S PG PP +GG +P+G PP
Sbjct: 267 PPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQG-----PPPP 321
Query: 253 QQHHQGPPPGG 263
QGPPP G
Sbjct: 322 PGKPQGPPPQG 332
Score = 134 bits (337), Expect = 3e-31
Identities = 95/256 (37%), Positives = 108/256 (42%), Gaps = 40/256 (15%)
Query: 35 PPGMGLNQNRG-------PMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQP 87
PP G N++R P GP P Q G +P PPPPP + Q PP PQ PPP
Sbjct: 162 PPPQGDNKSRSSRSPPGKPQGPPP-QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK 220
Query: 88 PPHPQPH------QQQQPP-----PPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATP 136
P P P + PP PPPQ ++P QGP P PG PP P P
Sbjct: 221 PQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQP---QGPPPPPGKPQGPPPQGGNKPQGP 277
Query: 137 PTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGP 196
P G P GP P + +PPG P PP G Q GPPPPP GP P
Sbjct: 278 PPPGKP--QGPPPQGGSKSRSSRSPPGKPQGPPPQGG-----NQPQGPPPPPGKPQGPPP 330
Query: 197 GPKQGPGPGGPKGGKMPGGPKPGGGP----GLSTPGGHPKPPHRGGGEPRGGRQHHPPY- 251
+ G P GP P GP P GG S PG PP + G P+G PP
Sbjct: 331 --QGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPP---PPAG 385
Query: 252 -HQQHHQGPPPGGPGG 266
+ Q Q PP G P G
Sbjct: 386 GNPQQPQAPPAGQPQG 401
Score = 132 bits (333), Expect = 8e-31
Identities = 105/277 (37%), Positives = 118/277 (42%), Gaps = 57/277 (20%)
Query: 35 PPGMGLNQNRGPMGPG------PGQSGPKPPIPPPPPHQQQQQPPPQ---------QPP- 78
PP G NQ +GP P P Q G KP PPPP + Q PPPQ PP
Sbjct: 121 PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG--KPQGPPPQGDNKSRSSRSPPG 178
Query: 79 -PQQPPPH--QPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPP-------AS 128
PQ PPP P P P + PPPQ +KP QGP P PG PP S
Sbjct: 179 KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP---QGP-PPPGKPQGPPPQGDNKSQS 234
Query: 129 SSAPPATPPTSGAPPGSGPGPT-PTPPPAVTSAPP---GAPPPTPPSSGVPTTPPQAGG- 183
+ +PP P G PP G P P PPP PP G P PP G P PP GG
Sbjct: 235 ARSPPGKP--QGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGS 292
Query: 184 -------PPPPPAAVPGPGPGPKQG--PGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPP 234
PP P P G QG P PG P+G GG KP G P PG PP
Sbjct: 293 KSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP---PPGKPQGPP 349
Query: 235 HRGGGEPRG-----GRQHHPPYHQQHH-QGPPPGGPG 265
+GG + R G+ PP + ++ QGPPP G
Sbjct: 350 PQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGG 386
Score = 108 bits (269), Expect = 2e-23
Identities = 77/205 (37%), Positives = 89/205 (43%), Gaps = 34/205 (16%)
Query: 35 PPGMGLNQNRG-------PMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQP 87
PP G N+++ P GP P Q G +P PPPPP + Q PP PQ PPP
Sbjct: 224 PPPQGDNKSQSARSPPGKPQGPPP-QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK 282
Query: 88 PPHPQPH------QQQQPP-----PPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATP 136
P P P + PP PPPQ ++P QGP P PG PP P P
Sbjct: 283 PQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQP---QGPPPPPGKPQGPPPQGGNKPQGP 339
Query: 137 PTSGAPPGSGPGPTPTPPPAVTSA--PPGAP--PPTPPSSGVPTTPPQAGGPPPPPAAVP 192
P PPG GP P SA PPG P PP + PP AGG P P A P
Sbjct: 340 P----PPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPP 395
Query: 193 GPGPGPKQGPGPGGPKGGKMPGGPK 217
G QGP P P+GG+ P+
Sbjct: 396 A---GQPQGP-PRPPQGGRPSRPPQ 416
Score = 93.2 bits (230), Expect = 7e-19
Identities = 75/210 (35%), Positives = 84/210 (40%), Gaps = 40/210 (19%)
Query: 68 QQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPA 127
Q++ P PQ PP ++ Q PP PP KP QGP P G P
Sbjct: 25 QEESPSLIAGNPQGAPPQGG------NKPQGPPSPP---GKP---QGPPPQ---GGNQPQ 69
Query: 128 SSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPP-----GAPPPTPPSSGVPTTPPQAG 182
PP P G PP G P PPP PP P +PP G P PP G
Sbjct: 70 GPPPPPGKP--QGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPP--GKPQGPPPQG 125
Query: 183 -----GPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGG----PGLSTPGGHPKP 233
GPPPPP GP P+ G P GP P GP P G S PG P
Sbjct: 126 GNQPQGPPPPPG--KPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGP 183
Query: 234 PHRGGGEPRGGRQHHPPYHQQHHQGPPPGG 263
P +GG +P+G PP QGPPP G
Sbjct: 184 PPQGGNQPQG-----PPPPPGKPQGPPPQG 208
Score = 75.5 bits (184), Expect = 2e-13
Identities = 57/160 (35%), Positives = 63/160 (39%), Gaps = 38/160 (23%)
Query: 32 RSPPP--GMGLNQNRGPMGP--GPGQSGPKPPIPPPPPHQQQQQPPPQ-------QPPPQ 80
+ PPP G +R P G GP G P PPPP + Q PPPQ PPP
Sbjct: 284 QGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG 343
Query: 81 QPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSG 140
+P PPPQ SK A+ P PG PP P PP
Sbjct: 344 KP----------------QGPPPQGGSKSRSARSP---PGKPQGPPQQEGNNPQGPP--- 381
Query: 141 APPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQ 180
PP G P PPA P G PP PP G P+ PPQ
Sbjct: 382 -PPAGGNPQQPQAPPA--GQPQG--PPRPPQGGRPSRPPQ 416
>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
sapiens]
Length = 309
Score = 131 bits (330), Expect = 2e-30
Identities = 101/286 (35%), Positives = 118/286 (41%), Gaps = 68/286 (23%)
Query: 25 RGGLHDFRSPPPG--------MGLNQNRGPMGPGPGQSGPKPPI-------PPPPPHQQQ 69
+GG R+PPP G NQ++GP P PG+ PP PPP P + +
Sbjct: 42 QGGNQPQRTPPPPGKPEGRPPQGGNQSQGPP-PRPGKPEGPPPQGGNQSQGPPPRPGKPE 100
Query: 70 QQPPP-----QQPPPQQPPPHQPPPHPQPHQQQQPP-------PPPQDSSKPVVAQGPGP 117
QPP Q PPP+ P PPP Q PP PPPQ ++ +QGP P
Sbjct: 101 GQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQ---SQGPPP 157
Query: 118 APGVGSAPPA----SSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPP------ 167
PG PP S PP P PP G + PPP P PPP
Sbjct: 158 RPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPP--RPGKPEGPPPQGGNQS 215
Query: 168 --TPPSSGVPTTPPQAG-----GPPPPPAAVPGPGP----GPKQGPGPGGPKGGKMPGG- 215
PP G P PP G GPPP P GP P P++ P PG P+G PGG
Sbjct: 216 QGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGN 275
Query: 216 PKPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHPPYHQQHHQGPPP 261
P+ P P G P P P+GGR H PP QG PP
Sbjct: 276 PQQPLPPPAGKPQGPPPP-------PQGGRPHRPP------QGQPP 308
Score = 123 bits (308), Expect = 7e-28
Identities = 87/234 (37%), Positives = 101/234 (43%), Gaps = 36/234 (15%)
Query: 46 PMGPGPGQSGPKPPIPPPPPHQQQQQPPP-----QQPPPQQPPPHQPPPHPQPHQQQQPP 100
P G P Q G +P PPPP + + +PP Q PPP+ P PPP Q PP
Sbjct: 36 PEGRRP-QGGNQPQRTPPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPP 94
Query: 101 PPPQDSSKPVV----AQGPGPAPGVGSAPPAS----SSAPPATPPTSGAPPGSGPGPTPT 152
P + +P +QGP P PG PP S PP P PP G +
Sbjct: 95 RPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQG 154
Query: 153 PPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGP-GPKQGPGPGGPKGGK 211
PPP PG P PP G Q+ GPPP P GP P G Q GP P+ GK
Sbjct: 155 PPPR-----PGKPEGPPPQGG-----NQSQGPPPHPGKPEGPPPQGGNQSQGP-PPRPGK 203
Query: 212 MPGGPKPGGGPGLSTPGGHP----KPPHRGGGEPRGGRQHHPPYHQQHHQGPPP 261
P GP P GG P P PP +GG +P+G PP H QGPPP
Sbjct: 204 -PEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQG-----PPPHPGKPQGPPP 251
Score = 93.2 bits (230), Expect = 7e-19
Identities = 71/206 (34%), Positives = 85/206 (41%), Gaps = 31/206 (15%)
Query: 71 QPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSS 130
+P ++P P PPP +P + PPQ ++ +QGP P PG
Sbjct: 35 KPEGRRPQGGNQPQRTPPPPGKPEGR-----PPQGGNQ---SQGPPPRPG---------- 76
Query: 131 APPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPP-----QAGGPP 185
P PP G GP P P P PP G P PP Q+ GPP
Sbjct: 77 -KPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPP 135
Query: 186 PPPAAVPGPGP-GPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGGGEPRGG 244
P P GP P G Q GP P+ GK P GP P GG P HP P G P+GG
Sbjct: 136 PRPGKPEGPPPQGGNQSQGP-PPRPGK-PEGPPPQGGNQSQGPPPHPGKPE--GPPPQGG 191
Query: 245 RQHH-PPYHQQHHQGPPPGGPGGRSE 269
Q PP +GPPP G G +S+
Sbjct: 192 NQSQGPPPRPGKPEGPPPQG-GNQSQ 216
Score = 41.6 bits (96), Expect = 0.003
Identities = 23/55 (41%), Positives = 26/55 (47%), Gaps = 10/55 (18%)
Query: 32 RSPPPGMGLNQNRGPMGPGPGQSGPKPPI------PPPPPHQQQQQPPPQQPPPQ 80
R PPPG + +GP PG P PP PPPPP + PPQ PPQ
Sbjct: 259 RPPPPG----RPQGPPPPGGNPQQPLPPPAGKPQGPPPPPQGGRPHRPPQGQPPQ 309
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 122 bits (306), Expect = 1e-27
Identities = 96/254 (37%), Positives = 106/254 (41%), Gaps = 41/254 (16%)
Query: 34 PPPGMGLNQNRGPMGPGPGQSGPKPP------IPPPPPHQQQQQPPPQQ-------PPPQ 80
P PG G+ P+ P PG P PP IPPPPP P P PPP
Sbjct: 925 PLPGAGIL----PLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPP 980
Query: 81 QPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVG--SAPPASSSAPPATPPT 138
P PPP P P PPPP + P P P PG G PP + P PP
Sbjct: 981 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPP----PPPLPGAGIPPPPPLPGAGIPPPPPL 1036
Query: 139 SGA---PPGSGPGPTPTPPPAVTSAPPGAPPPTP-PSSGVPTTPPQAGGPPPPPAAVPGP 194
GA PP PG PPP + A G PPP P P +G+P PP G PPP +PG
Sbjct: 1037 PGAGIPPPPPLPGAGIPPPPPLPGA--GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA 1094
Query: 195 G-PGPKQGPGPGGPKGGKMPGG--PKPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHPPY 251
G P P PG G P +PG P P PG P P PP G G P PP
Sbjct: 1095 GIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIP---PPPPLPGAGIP------PPPP 1145
Query: 252 HQQHHQGPPPGGPG 265
+ PPP PG
Sbjct: 1146 LPRVGIPPPPPLPG 1159
Score = 120 bits (301), Expect = 4e-27
Identities = 94/233 (40%), Positives = 104/233 (44%), Gaps = 41/233 (17%)
Query: 34 PPPGMGLNQNRGPMGPGPGQSGPKPP------IPPPPPHQQQQQPPPQQ-------PPPQ 80
P PG G+ P P PG P PP IPPPPP PPP PPP
Sbjct: 1013 PLPGAGIP----PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1068
Query: 81 QPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPA---SSSAPPATP- 136
P PPP P P PPPP + P P P PGVG PP + PP P
Sbjct: 1069 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPP----PPPLPGVGIPPPPPLPGAGIPPPPPL 1124
Query: 137 PTSGAPP-----GSG-PGPTPTPPPAVTSAPP----GAPPPTP-PSSGVPTTPPQAG-GP 184
P +G PP G+G P P P P + PP G PPP P P +G+P PP G G
Sbjct: 1125 PGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGI 1184
Query: 185 PPPPAAVPGPG-PGPKQGPGPGGPKGGKMPG-GPKPGGGPGLSTPG-GHPKPP 234
PPPP +PG G P P PG G P +PG G P P L PG G P PP
Sbjct: 1185 PPPP-PLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPP 1236
Score = 117 bits (294), Expect = 3e-26
Identities = 98/253 (38%), Positives = 109/253 (43%), Gaps = 36/253 (14%)
Query: 33 SPPPGMGLNQNRGPMGPGPGQSGPKPP---IPPPPPHQQQQQPPPQQPPPQQPPPHQPPP 89
S PG+G+ P P PG + P P IP PPP Q + PP PPP P PPP
Sbjct: 868 SSMPGLGMVPPPPP--PLPGMTVPTLPSTAIPQPPPLQGTEMLPP--PPPPLPGAGIPPP 923
Query: 90 HPQPHQQQQPPPPPQDSSKPVVAQGPGPAPG--VGSAPPASSSAPPATPPTSGA---PPG 144
P P P PP + P P P PG + PP + P PP GA PP
Sbjct: 924 PPLPGAGILPLPPLPGAGIPP----PPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPP 979
Query: 145 SGPGPTPTPPPAVTSAPPGAPPPTP-PSSGVPTTP--PQAGGPPPPP---AAVPGPGPGP 198
PG PPP + A G PPP P P +G+P P P AG PPPPP A +P P P P
Sbjct: 980 PLPGAGIPPPPPLPGA--GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1037
Query: 199 KQG--PGPGGPKGGKMPGGPKPGGG----PGLSTPGGHPKPPHRGGGEPRGGRQHHPPYH 252
G P P P G P P PG G P L G P PP G G P PP
Sbjct: 1038 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP------PPPPL 1091
Query: 253 QQHHQGPPPGGPG 265
PPP PG
Sbjct: 1092 PGAGIPPPPPLPG 1104
Score = 108 bits (270), Expect = 2e-23
Identities = 84/220 (38%), Positives = 92/220 (41%), Gaps = 38/220 (17%)
Query: 34 PPPGMGLNQNRGPMGPGPGQSGPKPP------IPPPPPHQQQQQPPPQQ-------PPPQ 80
P PG G+ P P PG P PP IPPPPP PPP PPP
Sbjct: 1035 PLPGAGIP----PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1090
Query: 81 QPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPA---SSSAPPATP- 136
P PPP P P PPPP + P P P PG G PP + PP P
Sbjct: 1091 LPGAGIPPPPPLPGVGIPPPPPLPGAGIPP----PPPLPGAGIPPPPPLPGAGIPPPPPL 1146
Query: 137 PTSGAPP-----GSG-PGPTPTPPPAVTSAPP----GAPPPTP-PSSGVPTTPPQAGGPP 185
P G PP G+G P P P P + PP G PPP P P G+P PP G
Sbjct: 1147 PRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGI 1206
Query: 186 PPPAAVPGPGPGPKQGPGPGGPKGGKMPGGP-KPGGGPGL 224
PPP +PG G P P P P G +P P P GP L
Sbjct: 1207 PPPPPLPGMGIPPAPAP-PLPPPGTGIPPPPLLPVSGPPL 1245
Score = 94.0 bits (232), Expect = 4e-19
Identities = 79/223 (35%), Positives = 87/223 (39%), Gaps = 37/223 (16%)
Query: 34 PPPGMGLNQNRGPMGPGPGQSGPKPP------IPPPPPHQQQQQPPPQQ-------PPPQ 80
P PG G+ P P PG P PP IPPPPP PPP PPP
Sbjct: 1079 PLPGAGIP----PPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1134
Query: 81 QPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPP-----ASSSAPPAT 135
P PPP P P PPPP + P P P PG G PP PP
Sbjct: 1135 LPGAGIPPPPPLPRVGIPPPPPLPGAGIPP----PPPLPGAGIPPPPPLPGVGIPPPPPL 1190
Query: 136 PPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPG 195
P PP PG PPP + PG PP+ P PP G PPPP V GP
Sbjct: 1191 PGVGIPPPPPLPGAGIPPPPPL----PGM--GIPPAPAPPLPPPGTGIPPPPLLPVSGPP 1244
Query: 196 PGPKQGPG--PGGPKGGKMPGGPKPGG--GPGLSTPGGHPKPP 234
P+ G P G +P P P G G G++ G K P
Sbjct: 1245 LLPQVGSSTLPTPQVCGFLP-PPLPSGLFGLGMNQDKGSRKQP 1286
Score = 76.6 bits (187), Expect = 7e-14
Identities = 83/262 (31%), Positives = 95/262 (36%), Gaps = 45/262 (17%)
Query: 35 PPGMGLNQNRGPMGPGPGQSGPKPPIPPP-----PPHQQQQQPPPQQPPPQ--QPPPHQP 87
PP GL R P PG +SGP+ P + Q QP QPPP P
Sbjct: 758 PPVDGL-PGRPPCPPG-AESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPP--P 813
Query: 88 PPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGP 147
P Q QP P S + + +PP P T + G
Sbjct: 814 PSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGL 873
Query: 148 GPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGG---PPPPP----AAVPGPGPGPKQ 200
G P PPP + PG PT PS+ +P PP G PPPPP A +P P P P
Sbjct: 874 GMVPPPPPPL----PGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGA 929
Query: 201 G-------PGPGGPKGGKMPGG------PKPGGG----PGLSTPGGHPKPPHRGGGEPRG 243
G PG G P +PG P PG G P L G P PP G G P
Sbjct: 930 GILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIP-- 987
Query: 244 GRQHHPPYHQQHHQGPPPGGPG 265
PP PPP PG
Sbjct: 988 ----PPPPLPGAGIPPPPPLPG 1005
Score = 44.7 bits (104), Expect = 3e-04
Identities = 57/219 (26%), Positives = 72/219 (32%), Gaps = 42/219 (19%)
Query: 33 SPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPP---------PHQQQQQP-PPQQPPPQQP 82
SP PG L +R +GP G +G P P P +P PQQPP
Sbjct: 240 SPQPGAFLGLDRFLLGPSGG-AGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGG 298
Query: 83 PPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPG------PAPGVGSAPP-----ASSSA 131
P P P Q P ++ P GPG P G G A A
Sbjct: 299 LPVSEAPS-LPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDA 357
Query: 132 PPATPPTSGAPP---------GSGPGPTPTPPPAVTSAP-PGAPPPTP---------PSS 172
P +P AP G P P A +A PG+P P+
Sbjct: 358 PRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGPDAPAAASLPGSPAPSQRCFKPYPLITPC 417
Query: 173 GVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGK 211
+ TT Q P P+ P P K+ P P +G +
Sbjct: 418 YIKTTTRQLSSPNHSPSQSPNQSPRIKRRPEPSLSRGSR 456
Score = 38.1 bits (87), Expect = 0.028
Identities = 51/203 (25%), Positives = 60/203 (29%), Gaps = 56/203 (27%)
Query: 67 QQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGP-----GPAPGV 121
QQQQQ Q QQ Q +P PP S +P G GP+ G
Sbjct: 206 QQQQQQQLQLQLQQQQQQQQLQGAEEP-----AAPPTAVSPQPGAFLGLDRFLLGPSGGA 260
Query: 122 GSAP---------------PASSSAPPATP---PTSGAPPGSGPGPTPTPPPAVTSAPPG 163
G AP P S +A P P P+ G P S P PA +P
Sbjct: 261 GEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSS 320
Query: 164 APPPTP---PSSGVPTTPPQAGGP----------PPPPAAVPGPGPGPKQG--------- 201
P P P P + G P PG P+ G
Sbjct: 321 TAFPFPEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGE 380
Query: 202 ------PGPGGPKGGKMPGGPKP 218
GP P +PG P P
Sbjct: 381 EPEEEAQGPDAPAAASLPGSPAP 403
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 116 bits (290), Expect = 8e-26
Identities = 100/317 (31%), Positives = 122/317 (38%), Gaps = 59/317 (18%)
Query: 10 GGGGGGFHR----RGGGGGRGGLHDFRSPPPGM------GLNQNRGPMGPGPGQSGPKPP 59
GGGGGGF GGGGG GG PPG+ G+ + R G +PP
Sbjct: 68 GGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPP 127
Query: 60 IPPPPPHQQQQQP--PPQQPP--PQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGP 115
+ PP +P PP P P P H+ P P+P + + PPP P SKP P
Sbjct: 128 LLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGP-PEPQRNRMPPPRPDVGSKPDSIPPP 186
Query: 116 GPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTP----------------PPAVTS 159
P+ P SS +PP G P PGPTP P P +S
Sbjct: 187 VPST---PRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSS 243
Query: 160 APPGAPPPTP--PSSGVPTTPPQAGGPPPPPA---------AVPGPGPGPKQGPGPGGPK 208
+P PP P PS + PP PPPPP AVP P P + P P P+
Sbjct: 244 SPFSNRPPLPPTPSRALDDKPP----PPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPR 299
Query: 209 GGKMPGGPKPGGGPGLSTPGGHPKPPHRGGGE--PRGGRQH------HPPYHQQHHQGPP 260
P P P S PG P PP G + PR +++ PP GP
Sbjct: 300 PSASSQAPPPPPPP--SRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPL 357
Query: 261 PGGPGGRSEEKISDSEG 277
P P R + D G
Sbjct: 358 PPPPSERPPPPVRDPPG 374
Score = 97.8 bits (242), Expect = 3e-20
Identities = 86/272 (31%), Positives = 105/272 (38%), Gaps = 61/272 (22%)
Query: 33 SPPPGMGLNQNRG--PMGPGPGQSGPKPPIPPPPPHQQ--------QQQP---------- 72
+P P NRG P+ GP Q P P PP P ++ +Q P
Sbjct: 190 TPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNR 249
Query: 73 PPQQPPPQQPPPHQPPPHPQP-------HQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAP 125
PP P P + +PPP P P H++ PPPPPQ++ KP V P P+
Sbjct: 250 PPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNN-KPPVPSTPRPS------- 301
Query: 126 PASSSAPPATPPTS--GAPP----GSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPP 179
ASS APP PP S G PP SG TP P S PP P P PP
Sbjct: 302 -ASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPP 360
Query: 180 QAGGPPPPPAAVPGPGPGPKQGPGP---GGPKGGKMPGGPKPGGGPGLSTPGGHPKPPHR 236
+ PPPP PG GP P P G +P P+ G+ +P P+PP
Sbjct: 361 PSERPPPPVRDPPGRS-GPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPL- 418
Query: 237 GGGEPRGGRQHHPPYHQQHHQGPPPGGPGGRS 268
PP + G PP P S
Sbjct: 419 ------------PP--DRPSAGAPPPPPPSTS 436
Score = 97.4 bits (241), Expect = 4e-20
Identities = 110/334 (32%), Positives = 124/334 (37%), Gaps = 92/334 (27%)
Query: 10 GGGGGGFHRRGGGG--GRGGLHDFRSP--------------------PPGMGLNQNRGPM 47
GGGGGG GGGG G GGL P PPG G + + P
Sbjct: 83 GGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPG-GRSTSAKPF 141
Query: 48 GP--GPGQ---------SGPKPP----IPPPPPHQQQQQ-----PPPQQPPPQQPPPHQ- 86
P GPG+ SGP P +PPP P + P P P P Q PH
Sbjct: 142 SPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNR 201
Query: 87 -PPPHP----QPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGS--APPASSSAP----PAT 135
PP P QP PPP P + G A G GS P SSS+P P
Sbjct: 202 GSPPVPGGPRQPSPGPTPPPFPGNR---------GTALGGGSIRQSPLSSSSPFSNRPPL 252
Query: 136 PPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSG---VPTTP-PQAGG---PPPPP 188
PPT P P P P S A PP PP + VP+TP P A PPPPP
Sbjct: 253 PPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPP 312
Query: 189 AAVPGPGPGPKQGPG----PGGPK-----GGKMPGGPKPG-GGPGLSTPGGHPKPPHRGG 238
+ PGP P P G P P+ P P PG GP P P PP R
Sbjct: 313 PSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVR-- 370
Query: 239 GEPRGGRQHHPPYHQQHHQGPPPGGPGGRSEEKI 272
+P G PP PPP G + +
Sbjct: 371 -DPPGRSGPLPP--------PPPVSRNGSTSRAL 395
Score = 92.4 bits (228), Expect = 1e-18
Identities = 76/239 (31%), Positives = 91/239 (38%), Gaps = 39/239 (16%)
Query: 19 RGGGGGRGGLHDFRSPPPGMGLNQNRGPMGPGPGQS-GPKPPIPPPP----PHQQQQQPP 73
RG G G + +SP NR P+ P P ++ KPP PPPP P ++ P
Sbjct: 226 RGTALGGGSIR--QSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVP 283
Query: 74 PQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPP 133
P PPPQ P P P+P Q PPPP PP S PP
Sbjct: 284 P--PPPQNNKPPVPST-PRPSASSQAPPPP---------------------PPPSRPGPP 319
Query: 134 ATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPG 193
PP+S SG TP P S PP P P PP + PPPP PG
Sbjct: 320 PLPPSS-----SGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPG 374
Query: 194 -PGPGPKQGP-GPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHPP 250
GP P P G +P P+ G+ +P P+PP P G PP
Sbjct: 375 RSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPP-LPPDRPSAGAPPPPP 432
Score = 32.7 bits (73), Expect = 1.2
Identities = 26/93 (27%), Positives = 34/93 (36%), Gaps = 10/93 (10%)
Query: 613 GGGGAMNMGDPYGSGGQKFPPLGGGGGIGYEANPGVPPATMSGSMMGSDMRTERFGQGGA 672
GGGG G +G GG GGGG G PG+ G + + M R
Sbjct: 69 GGGGGFGGGGGFGGGGGG----GGGGSFGGGGPPGL------GGLFQAGMPKLRSTANRD 118
Query: 673 GPVGGQGPRGMGPGTPAGYGRGREEYEGPNKKP 705
GG P + PG + + GP + P
Sbjct: 119 NDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFP 151
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 116 bits (290), Expect = 8e-26
Identities = 100/317 (31%), Positives = 122/317 (38%), Gaps = 59/317 (18%)
Query: 10 GGGGGGFHR----RGGGGGRGGLHDFRSPPPGM------GLNQNRGPMGPGPGQSGPKPP 59
GGGGGGF GGGGG GG PPG+ G+ + R G +PP
Sbjct: 68 GGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPP 127
Query: 60 IPPPPPHQQQQQP--PPQQPP--PQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGP 115
+ PP +P PP P P P H+ P P+P + + PPP P SKP P
Sbjct: 128 LLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGP-PEPQRNRMPPPRPDVGSKPDSIPPP 186
Query: 116 GPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTP----------------PPAVTS 159
P+ P SS +PP G P PGPTP P P +S
Sbjct: 187 VPST---PRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSS 243
Query: 160 APPGAPPPTP--PSSGVPTTPPQAGGPPPPPA---------AVPGPGPGPKQGPGPGGPK 208
+P PP P PS + PP PPPPP AVP P P + P P P+
Sbjct: 244 SPFSNRPPLPPTPSRALDDKPP----PPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPR 299
Query: 209 GGKMPGGPKPGGGPGLSTPGGHPKPPHRGGGE--PRGGRQH------HPPYHQQHHQGPP 260
P P P S PG P PP G + PR +++ PP GP
Sbjct: 300 PSASSQAPPPPPPP--SRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPL 357
Query: 261 PGGPGGRSEEKISDSEG 277
P P R + D G
Sbjct: 358 PPPPSERPPPPVRDPPG 374
Score = 97.8 bits (242), Expect = 3e-20
Identities = 86/272 (31%), Positives = 105/272 (38%), Gaps = 61/272 (22%)
Query: 33 SPPPGMGLNQNRG--PMGPGPGQSGPKPPIPPPPPHQQ--------QQQP---------- 72
+P P NRG P+ GP Q P P PP P ++ +Q P
Sbjct: 190 TPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNR 249
Query: 73 PPQQPPPQQPPPHQPPPHPQP-------HQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAP 125
PP P P + +PPP P P H++ PPPPPQ++ KP V P P+
Sbjct: 250 PPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNN-KPPVPSTPRPS------- 301
Query: 126 PASSSAPPATPPTS--GAPP----GSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPP 179
ASS APP PP S G PP SG TP P S PP P P PP
Sbjct: 302 -ASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPP 360
Query: 180 QAGGPPPPPAAVPGPGPGPKQGPGP---GGPKGGKMPGGPKPGGGPGLSTPGGHPKPPHR 236
+ PPPP PG GP P P G +P P+ G+ +P P+PP
Sbjct: 361 PSERPPPPVRDPPGRS-GPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPL- 418
Query: 237 GGGEPRGGRQHHPPYHQQHHQGPPPGGPGGRS 268
PP + G PP P S
Sbjct: 419 ------------PP--DRPSAGAPPPPPPSTS 436
Score = 97.4 bits (241), Expect = 4e-20
Identities = 110/334 (32%), Positives = 124/334 (37%), Gaps = 92/334 (27%)
Query: 10 GGGGGGFHRRGGGG--GRGGLHDFRSP--------------------PPGMGLNQNRGPM 47
GGGGGG GGGG G GGL P PPG G + + P
Sbjct: 83 GGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPG-GRSTSAKPF 141
Query: 48 GP--GPGQ---------SGPKPP----IPPPPPHQQQQQ-----PPPQQPPPQQPPPHQ- 86
P GPG+ SGP P +PPP P + P P P P Q PH
Sbjct: 142 SPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNR 201
Query: 87 -PPPHP----QPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGS--APPASSSAP----PAT 135
PP P QP PPP P + G A G GS P SSS+P P
Sbjct: 202 GSPPVPGGPRQPSPGPTPPPFPGNR---------GTALGGGSIRQSPLSSSSPFSNRPPL 252
Query: 136 PPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSG---VPTTP-PQAGG---PPPPP 188
PPT P P P P S A PP PP + VP+TP P A PPPPP
Sbjct: 253 PPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPP 312
Query: 189 AAVPGPGPGPKQGPG----PGGPK-----GGKMPGGPKPG-GGPGLSTPGGHPKPPHRGG 238
+ PGP P P G P P+ P P PG GP P P PP R
Sbjct: 313 PSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVR-- 370
Query: 239 GEPRGGRQHHPPYHQQHHQGPPPGGPGGRSEEKI 272
+P G PP PPP G + +
Sbjct: 371 -DPPGRSGPLPP--------PPPVSRNGSTSRAL 395
Score = 92.4 bits (228), Expect = 1e-18
Identities = 76/239 (31%), Positives = 91/239 (38%), Gaps = 39/239 (16%)
Query: 19 RGGGGGRGGLHDFRSPPPGMGLNQNRGPMGPGPGQS-GPKPPIPPPP----PHQQQQQPP 73
RG G G + +SP NR P+ P P ++ KPP PPPP P ++ P
Sbjct: 226 RGTALGGGSIR--QSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVP 283
Query: 74 PQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPP 133
P PPPQ P P P+P Q PPPP PP S PP
Sbjct: 284 P--PPPQNNKPPVPST-PRPSASSQAPPPP---------------------PPPSRPGPP 319
Query: 134 ATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPG 193
PP+S SG TP P S PP P P PP + PPPP PG
Sbjct: 320 PLPPSS-----SGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPG 374
Query: 194 -PGPGPKQGP-GPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHPP 250
GP P P G +P P+ G+ +P P+PP P G PP
Sbjct: 375 RSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPP-LPPDRPSAGAPPPPP 432
Score = 32.7 bits (73), Expect = 1.2
Identities = 26/93 (27%), Positives = 34/93 (36%), Gaps = 10/93 (10%)
Query: 613 GGGGAMNMGDPYGSGGQKFPPLGGGGGIGYEANPGVPPATMSGSMMGSDMRTERFGQGGA 672
GGGG G +G GG GGGG G PG+ G + + M R
Sbjct: 69 GGGGGFGGGGGFGGGGGG----GGGGSFGGGGPPGL------GGLFQAGMPKLRSTANRD 118
Query: 673 GPVGGQGPRGMGPGTPAGYGRGREEYEGPNKKP 705
GG P + PG + + GP + P
Sbjct: 119 NDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFP 151
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 111 bits (278), Expect = 2e-24
Identities = 80/245 (32%), Positives = 93/245 (37%), Gaps = 38/245 (15%)
Query: 46 PMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQD 105
P P P + P PP P P P+ P PP PP P+ P P+
Sbjct: 931 PASPSPKGAPTPPAATPPSPKGGPATPSPKWAPT---PPAATPPSPKGGPAT---PSPKG 984
Query: 106 SSKPVVAQGPGPAPGVGSAPPASSSAPPA-TPPTSGAPPGSGPGP--TPTPPPAVTSAPP 162
+ P A P P G + P + PPA TPP+ P + P P TPP A +P
Sbjct: 985 APTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPK 1044
Query: 163 GAPPPTPPSSGVPTTP-------------PQAGGPPPPPAAVPGPGPGPKQGPGPGGPKG 209
G+P TP G PTTP P G P PPAA P P PK GP PKG
Sbjct: 1045 GSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATP---PSPKGGPATPSPKG 1101
Query: 210 GKMPGGPKPGGGPGLSTPGGHPKPPHRGG--------GEPRGGRQHHPPYHQQHHQGPPP 261
MP P S GG PPH+G P+GG PP P
Sbjct: 1102 APMPPAATPP-----SPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATP 1156
Query: 262 GGPGG 266
P G
Sbjct: 1157 PSPKG 1161
Score = 105 bits (261), Expect = 2e-22
Identities = 85/279 (30%), Positives = 104/279 (37%), Gaps = 35/279 (12%)
Query: 21 GGGGRGGLHDFRSPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPP---------PHQQQQQ 71
GG L +PP + GP P P + P PP PP PH+
Sbjct: 1069 GGPATPSLKGAPTPPAATPPSPKGGPATPSP-KGAPMPPAATPPSPKGGLATPPHKGAPT 1127
Query: 72 PPPQQPPPQQPPPHQPPPHPQPHQQQQPPP---------PPQDSSKPVVAQGPGPAPGVG 122
P PP + PPP P PP PP+ + A P P G+
Sbjct: 1128 TPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLA 1187
Query: 123 S-APPASSSAPPATPPT------SGAPPGSGPGPTPTPPPA----VTSAPPGAPPP---T 168
+ +P + + P ATPP+ + +P G+ P TPP T +P GAP T
Sbjct: 1188 TPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT 1247
Query: 169 PPS-SGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTP 227
PPS G P TPP G P P PAA P G P G + P P GGP S P
Sbjct: 1248 PPSPKGGPATPPPKGAPTP-PAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPP 1306
Query: 228 GGHPKPPHRGGGEPRGGRQHHPPYHQQHHQGPPPGGPGG 266
G P PP P+G PP P P G
Sbjct: 1307 KGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKG 1345
Score = 97.8 bits (242), Expect = 3e-20
Identities = 80/250 (32%), Positives = 91/250 (36%), Gaps = 22/250 (8%)
Query: 33 SPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQ---QPPPQQPP-PHQPP 88
+PP + GP P P + P PP P P P+ PP PP P P
Sbjct: 941 TPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGP 1000
Query: 89 PHPQPHQQQQPPP--PPQDSSKPVVAQGP-GPAPGVGSAPPASSSAPPATPPTSGAPPGS 145
P P PP PP P P G + + PP+ +P ATP GAP
Sbjct: 1001 ATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTP 1060
Query: 146 GPG-PTPTPPPAVTS-----APPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPK 199
P+P PA S PP A PP+P G P TP G P P PAA P P PK
Sbjct: 1061 AATLPSPKGGPATPSLKGAPTPPAATPPSP--KGGPATPSPKGAPMP-PAATP---PSPK 1114
Query: 200 QGPGPGGPKGGKMPGG---PKPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHPPYHQQHH 256
G KG P P GG P G P P P+GG PP
Sbjct: 1115 GGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTT 1174
Query: 257 QGPPPGGPGG 266
P P G
Sbjct: 1175 PAATPPSPKG 1184
Score = 96.3 bits (238), Expect = 9e-20
Identities = 86/268 (32%), Positives = 97/268 (36%), Gaps = 35/268 (13%)
Query: 33 SPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQ---QPPPQQPPPHQ--P 87
+PP + GP P P + P PP P P P+ PP PP + P
Sbjct: 964 TPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSP 1023
Query: 88 PPHPQPHQQQQPPP--PPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAP-PG 144
P P PP PP P P AP +A S PATP GAP P
Sbjct: 1024 AATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPP 1083
Query: 145 SGPGPTPTPPPAVTSAPPGAP---PPTPPS-SGVPTTPPQAGGPPPPPAAVPGP-----G 195
+ P+P PA T +P GAP TPPS G TPP G P P A P P
Sbjct: 1084 AATPPSPKGGPA-TPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLAT 1142
Query: 196 PGPKQGP-----GPGGPKGG---KMPGG---------PKPGGGPGLSTPGGHPKPPHRGG 238
P PK P P PKGG P G P P GG +P G P P
Sbjct: 1143 PPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP 1202
Query: 239 GEPRGGRQHHPPYHQQHHQGPPPGGPGG 266
P+GG P P P G
Sbjct: 1203 PSPKGGLATPSPKGAPTTPAATPPSPKG 1230
Score = 96.3 bits (238), Expect = 9e-20
Identities = 91/276 (32%), Positives = 106/276 (38%), Gaps = 49/276 (17%)
Query: 25 RGGLHDFRSPPPGMGLNQNRGPMGPGPGQSGPKPP-------IPPPPPHQQQQQPPPQQP 77
+GGL PP G P P G + P P PP P P P+
Sbjct: 1137 KGGLAT--PPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGA 1194
Query: 78 P--PQQPPPHQ------PPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASS 129
P P PP P P P PP P+ + P AP +A P S
Sbjct: 1195 PTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG---LATPSPKGAPTTPAATPPSP 1251
Query: 130 SAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPP--GAPPP---TPPS--SGVPTTPPQAG 182
PATPP GAP + P TP + PP GAP P TPPS G T+PP+
Sbjct: 1252 KGGPATPPPKGAP--TPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPK-- 1307
Query: 183 GPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGG---PKPGGGPGL-----STPGGHPKPP 234
G P PPAA P P PK PG PKG P P P G P L S+ GG P
Sbjct: 1308 GAPTPPAATP---PSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPS 1364
Query: 235 HRGGGEP-------RGGRQHHPPYHQQHHQGPPPGG 263
+ G P +GG PP ++ P P G
Sbjct: 1365 SKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKG 1400
Score = 94.4 bits (233), Expect = 3e-19
Identities = 68/217 (31%), Positives = 80/217 (36%), Gaps = 30/217 (13%)
Query: 33 SPPPGMGLNQNRG-PMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHP 91
SP G+ +G P P PK + P P P P P+ P PP
Sbjct: 1204 SPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGA 1263
Query: 92 QPHQQQQPP--------PPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTS---- 139
PP PP + + P V P P G ++PP + PPA P S
Sbjct: 1264 PTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGS 1323
Query: 140 -GAPPGSG-PGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPG 197
G PP G P P PP+ P P TP S G PTTP G P PPAA P G
Sbjct: 1324 PGTPPPKGAPTPPAVTPPS-PKGTPTLPATTPSSKGGPTTPSSKEG-PTPPAATPSHKGG 1381
Query: 198 PKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPP 234
P P P P GP + +P G P P
Sbjct: 1382 PAMTP-------------PSPKRGPAIPSPKGDPTSP 1405
Score = 92.0 bits (227), Expect = 2e-18
Identities = 85/277 (30%), Positives = 98/277 (35%), Gaps = 62/277 (22%)
Query: 33 SPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPH---------QQQQQPPPQQPP-PQQP 82
+PP + GP P P + P + PP P + PP PP P+
Sbjct: 987 TPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGS 1046
Query: 83 PPHQPPPH----------PQPHQQQQPP-----PPPQDSSKPVVAQGPG-PAPGVGSAPP 126
P P P P P P P P ++ P GP P+P PP
Sbjct: 1047 PAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPP 1106
Query: 127 ASSSAPP----ATPPTSGAP------PGSGPGPTPTPPPAVTSAPPGAPPPTPPS-SGVP 175
A++ P ATPP GAP P S G TPPP P P TPPS G
Sbjct: 1107 AATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPP---KGAPTTPAATPPSPKGGL 1163
Query: 176 TTPPQAGGPPPPPAAVPGP-----GPGPKQGP-----GPGGPKGGKMPGGPK-------- 217
TPP G P P A P P P PK P P PKGG PK
Sbjct: 1164 ATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAA 1223
Query: 218 ----PGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHPP 250
P GG +P G P P P+GG PP
Sbjct: 1224 TPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPP 1260
Score = 90.5 bits (223), Expect = 5e-18
Identities = 77/232 (33%), Positives = 90/232 (38%), Gaps = 29/232 (12%)
Query: 46 PMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQ---PPPHQPPPHPQPHQQQQPPPP 102
P P P + P P P + PP + P P P P + P P P +Q P
Sbjct: 856 PTPPSP-KGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAP---KQAPAL 911
Query: 103 PQDSSKPVVAQGPGPAPGVGSAP-PASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAP 161
SS P A+ G+ ++P P + PPA P S P GP TP P P
Sbjct: 912 SMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPS---PKGGPA---TPSPKWAPTP 965
Query: 162 PGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGG---PKP 218
P A PP+P G P TP G P P PAA P P PK GP PKG P P P
Sbjct: 966 PAATPPSP--KGGPATPSPKGAPTP-PAATP---PSPKGGPATPSPKGAPTPPAVTPPSP 1019
Query: 219 GGGPGLST-PGGHPKPPHRGGGEPRGGRQHHP-----PYHQQHHQGPPPGGP 264
G P + P G PP P+G P P P GGP
Sbjct: 1020 KGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGP 1071
Score = 84.7 bits (208), Expect = 3e-16
Identities = 78/227 (34%), Positives = 89/227 (39%), Gaps = 26/227 (11%)
Query: 32 RSPPPGMGLNQNRGPMGPGPGQSGPKPPIPPP--PPHQQQQQPPPQQPPP-QQPPPHQPP 88
+ PP G + GP P S P P+ P + Q P P P P
Sbjct: 806 KRPPTKKG---SAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPK 862
Query: 89 PHPQPHQQQQPPP-----PPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPP 143
P P P PP+++ P V P P G A PA AP A TS +P
Sbjct: 863 GAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEG--PATPAPKQAP-ALSMTSSSPK 919
Query: 144 GSGPGPTPTPPPAVTSAPPGAPP---PTPPS-SGVPTTPPQAGGPPPPPAAVPGPGPGPK 199
+ P P PA S P GAP TPPS G P TP P PPAA P P PK
Sbjct: 920 KARATPAPKGIPASPS-PKGAPTPPAATPPSPKGGPATPSPKWA-PTPPAATP---PSPK 974
Query: 200 QGPGPGGPKGGKMPGG---PKPGGGPGLSTPGGHPKPPHRGGGEPRG 243
GP PKG P P P GGP +P G P PP P+G
Sbjct: 975 GGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKG 1021
Score = 83.2 bits (204), Expect = 8e-16
Identities = 72/234 (30%), Positives = 84/234 (35%), Gaps = 44/234 (18%)
Query: 33 SPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPP---------PHQQQQQPPPQQPPPQQPP 83
+PP G GP P P + P PP PP PH+ P PP +
Sbjct: 1247 TPPSPKG-----GPATPPP-KGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGG 1300
Query: 84 PHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTS-GAP 142
P PP P PP P+ S +G P V P + PAT P+S G P
Sbjct: 1301 PATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGP 1360
Query: 143 --PGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQ 200
P S GPTP PA T + G P TPPS P G P PA +P PK+
Sbjct: 1361 TTPSSKEGPTP---PAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIP---LSPKK 1414
Query: 201 GP-------GPGGPKGG-------------KMPGGPKPGGGPGLSTPGGHPKPP 234
P G P G K P P GGP + G P P
Sbjct: 1415 APATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLP 1468
Score = 65.1 bits (157), Expect = 2e-10
Identities = 71/264 (26%), Positives = 85/264 (32%), Gaps = 65/264 (24%)
Query: 35 PPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQP----------------P 78
PP +G G P + P PP PP + P P P
Sbjct: 1312 PPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTP 1371
Query: 79 PQQPPPHQPPPH---PQPHQQQQPPPPPQDSSKP-VVAQGPGPAPGV-----GSAPPASS 129
P P H+ P P P + P P D + P V+ P AP G+A P+
Sbjct: 1372 PAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKG 1431
Query: 130 S-APPATPPTS-------GAPPGSGPG---------------PTPTPPPA----VTSAPP 162
PPA P S AP G GP P+P PPA TS+ P
Sbjct: 1432 DLTPPAVTPVSLKKAPATSAPKG-GPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSP 1490
Query: 163 GAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGP---------KQGPGPGGPKGGKMP 213
P TP G PT P P A P P K+ P PK +P
Sbjct: 1491 KKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIP 1550
Query: 214 GG---PKPGGGPGLSTPGGHPKPP 234
P P P + TP P P
Sbjct: 1551 PAMTVPSPKKTPAIPTPKEAPATP 1574
Score = 61.6 bits (148), Expect = 2e-09
Identities = 60/232 (25%), Positives = 70/232 (30%), Gaps = 69/232 (29%)
Query: 100 PPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATP----------------------P 137
P P S P + P G P + + P +P
Sbjct: 794 PSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATT 853
Query: 138 TSGAPPGSGPGPTP-----------------TPPPAVTSAP-----PGAPPP-------- 167
S PP PTP TP P+V + P P P P
Sbjct: 854 HSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSM 913
Query: 168 ----------TPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGG-- 215
TP G+P +P G P PPAA P P PK GP PK P
Sbjct: 914 TSSSPKKARATPAPKGIPASPSPKGA-PTPPAATP---PSPKGGPATPSPKWAPTPPAAT 969
Query: 216 -PKPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHPPYHQQHHQGPPPGGPGG 266
P P GGP +P G P PP P+GG P P P G
Sbjct: 970 PPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKG 1021
Score = 60.5 bits (145), Expect = 5e-09
Identities = 51/167 (30%), Positives = 62/167 (37%), Gaps = 16/167 (9%)
Query: 56 PKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPP-PHPQPHQQQQPPPPPQDSSKPVVAQG 114
P P PP P Q P++ P P P P P ++ P P P+
Sbjct: 1472 PPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTA 1531
Query: 115 -------PGP-APGVGSAPPASS-SAPPATP--PTSGAPPGSGPGPTPTPPPAVT-SAPP 162
P AP PPA + +P TP PT P + + PPAVT S
Sbjct: 1532 TLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYK 1591
Query: 163 GAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKG 209
GAP P T P P PPA P P P++GP PKG
Sbjct: 1592 GAPSPKELLIPPAVTSPSPKEAPTPPAVTP---PSPEKGPATPAPKG 1635
Score = 52.4 bits (124), Expect = 1e-06
Identities = 54/222 (24%), Positives = 71/222 (31%), Gaps = 31/222 (13%)
Query: 51 PGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPH---PQPHQQQQPP----PPP 103
P + P P P P ++ P PP P + P P + PP P P
Sbjct: 1551 PAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSP 1610
Query: 104 QDSSKPVVAQGPGPAPGVGS-APPASSSAPPATP------PTSGA----------PPGSG 146
+++ P P P G + AP + ++PP TP PTS A P S
Sbjct: 1611 KEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASK 1670
Query: 147 -----PGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPP--PPAAVPGPGPGPK 199
GPT V AP P T P+ P T + PP P + GP
Sbjct: 1671 GLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPL 1730
Query: 200 QGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGGGEP 241
P + G +P G PP P
Sbjct: 1731 STVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTP 1772
Score = 49.7 bits (117), Expect = 9e-06
Identities = 61/217 (28%), Positives = 71/217 (32%), Gaps = 53/217 (24%)
Query: 34 PPPGMGLNQNRGP-------MGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQ 86
P GL +GP + P P + P I P Q + PP P P
Sbjct: 1666 PQASKGLPAKKGPTALKEVLVAPAPEST---PIITAPTRKGPQTKKSSATSPPICPDPSA 1722
Query: 87 PPPHPQPHQQQQPPP--PPQ-DSSKPVVAQGPGPAPGVGSAPPASSSAPPATP------- 136
P P P P Q DSSK + +P APP S ++ P T
Sbjct: 1723 KNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVL 1782
Query: 137 --PTSGA------PPGS---GPGPTPTPPPAVTSAP------------PGAP-------- 165
P S + PP S P P PT PP P P AP
Sbjct: 1783 PKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLP 1842
Query: 166 --PPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQ 200
PP P S GVP P P A +P P P KQ
Sbjct: 1843 LIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQ 1879
Score = 43.5 bits (101), Expect = 7e-04
Identities = 50/170 (29%), Positives = 57/170 (33%), Gaps = 49/170 (28%)
Query: 71 QPPPQQPPPQQPPPHQPP--------PHPQPHQQQQPP---PPPQDSSKPVVAQGPGP-A 118
QP P PPP P P Q P P P P P P PQ SS + G P A
Sbjct: 40 QPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEA 99
Query: 119 P-------GVGSAPPASSSAPPATPPTSGAPPGSG-------------------PGPTPT 152
P G +P A + A P PT P S P T
Sbjct: 100 PTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLT 159
Query: 153 PPPAVTSAPPG------AP-PPTPPSSGVPTTP----PQAGGPPPPPAAV 191
PP+V A G AP P+ P + + P P G P PP V
Sbjct: 160 SPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIV 209
Score = 37.7 bits (86), Expect = 0.037
Identities = 32/129 (24%), Positives = 48/129 (37%), Gaps = 16/129 (12%)
Query: 93 PHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPT 152
P +Q+ P P +++ ++ +G P + PP +P P + +P
Sbjct: 10 PATEQELPQPQAETAVLPMSSALSVTAALGQ--PGPTLPPPCSPAPQQCPLSAANQASPF 67
Query: 153 PPPAVTSAPPGAPPPTPPSSG----------VPTTPPQAGGPPPPPAAV----PGPGPGP 198
P P+ ++ P P SSG PT P GPP PAA+ P P
Sbjct: 68 PSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTL 127
Query: 199 KQGPGPGGP 207
K P P
Sbjct: 128 KGTPSSSAP 136
Score = 37.4 bits (85), Expect = 0.048
Identities = 63/300 (21%), Positives = 79/300 (26%), Gaps = 115/300 (38%)
Query: 74 PQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPP 133
P+ P ++ P P + P PQ++ P+ + AP S P
Sbjct: 685 PKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLAT--------LVLAPEIPKSVPS 736
Query: 134 ATPPTSGAPPG-----------------SGPGPTPT----------------------PP 154
+ P +G PPG S P PT P
Sbjct: 737 PSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSP 796
Query: 155 PAVTSAPPGAPPPTPPSSGVP--------------------------------------- 175
V+ +P PPT S P
Sbjct: 797 LGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSP 856
Query: 176 TTPPQAGGPPP-------------PPAAVPGPG----PGPKQGPGPGGPKGG-------- 210
T P G P P PP P P P PK+GP PK
Sbjct: 857 TPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSS 916
Query: 211 ---KMPGGPKPGGGPGLSTPGGHPKPPHRGGGEPRGG-RQHHPPYHQQHHQGPPPGGPGG 266
K P P G P +P G P PP P+GG P + PP GG
Sbjct: 917 SPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGG 976
Score = 33.5 bits (75), Expect = 0.70
Identities = 33/88 (37%), Positives = 40/88 (45%), Gaps = 12/88 (13%)
Query: 109 PVVAQGP----GPAPGVGSAPPASSSAPPAT--PPTSGAPP-GSGP--GPTPTPPPAVTS 159
P+VAQ P G P V + P ++AP T T +PP SGP PT P A+
Sbjct: 426 PLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVM 485
Query: 160 APPGAPPPTPPSSGVPTTPPQAGGPPPP 187
AP P PS+ V TT PP P
Sbjct: 486 APVA---PKEPSTQVATTLRIPVSPPLP 510
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 110 bits (274), Expect = 6e-24
Identities = 86/234 (36%), Positives = 98/234 (41%), Gaps = 34/234 (14%)
Query: 9 RGGGGGGFHRRG---GGGGRGGLHDFRSPPPGMGLNQNRGPMGPG-------PGQSGPKP 58
+ G GG R GG GRG R P G ++ GP GPG GQ+ P+P
Sbjct: 185 KAGPPGGSSRAAFPQGGRGRG-----RFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRP 239
Query: 59 PIPPPPPHQQQQQPPPQQ--PPPQQPPPHQ----PPPHPQPHQQ-QQPP--PPPQDSSKP 109
P+ PP P PPP Q PPP PP++ PPP P Q QPP P P P
Sbjct: 240 PLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPP 299
Query: 110 VVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGS-GPGPTPTPPPAVTSAPPGAPPPT 168
V GP P P PP PP P PPG GP T PPP + PPGAPPP
Sbjct: 300 VPGYGPPPGP-----PPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPA 354
Query: 169 PPSSGVPTTPPQAGGPPPPPAAVPGP----GPGPKQGPGPGGPKGGKMPGGPKP 218
P + PP G P + P P G P G GP G +M P
Sbjct: 355 PHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREMDTARTP 408
Score = 105 bits (261), Expect = 2e-22
Identities = 86/258 (33%), Positives = 91/258 (35%), Gaps = 53/258 (20%)
Query: 14 GGFHRRGGGGGRGGLHDFRSPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPP 73
G G G GG P G G + G + G GP P PPPP Q PP
Sbjct: 178 GQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPP 237
Query: 74 PQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPP 133
PP PP PP P P Q PPP GP P G PP
Sbjct: 238 R---PPLGPPGPPGPPGPPPPGQVLPPP----------LAGP---PNRGDRPP------- 274
Query: 134 ATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPG 193
PP PG P P + PPG PPP P P PP GPPPPP
Sbjct: 275 --------PPVLFPGQ-PFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPP----- 320
Query: 194 PGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPK----PPHRGGGEPRGGRQHHP 249
GP P + PGP GP P PG PG P H PP G P
Sbjct: 321 -GPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMP-------- 371
Query: 250 PYHQQHHQGPPPGGPGGR 267
+GPPP P GR
Sbjct: 372 ---TSDSRGPPPTDPYGR 386
>gi|19924099 synapsin I isoform Ia [Homo sapiens]
Length = 705
Score = 110 bits (274), Expect = 6e-24
Identities = 79/240 (32%), Positives = 94/240 (39%), Gaps = 29/240 (12%)
Query: 42 QNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPP 101
Q + PG G G P P +Q Q P P Q+PPP PP P P Q+Q PP
Sbjct: 421 QRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPP 480
Query: 102 ----PPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAV 157
PP + + GP + P+ +SA P P + APP G G P
Sbjct: 481 LQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSA-PQQPASQAAPPTQGQGRQSRPVAGG 539
Query: 158 TSAPPGAPPPTPPSSGVPTTPPQA------GGPPPPPAAVPGPGPGPKQG-----PGPGG 206
APP A PP PS PPQA GP PP A+ PG +QG PGP G
Sbjct: 540 PGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAG 599
Query: 207 PKGGKMPGGPKPGGGPGLST--------PGGHPKP-----PHRGGGEPRGGRQHHPPYHQ 253
P GP P GP + P G PKP P + P PP+ Q
Sbjct: 600 PTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQ 659
Score = 91.3 bits (225), Expect = 3e-18
Identities = 81/247 (32%), Positives = 94/247 (38%), Gaps = 42/247 (17%)
Query: 18 RRGGGGGRGGLHDFRSPPPG---MGLNQNRGPMGP----------GPGQSGP-----KPP 59
+R GRG ++P PG +G ++ P GP GP Q GP PP
Sbjct: 423 QRDASPGRGS--HGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPP 480
Query: 60 IPPPPPHQQQQQ-----PPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQG 114
+ PP Q QQ PP P PQ+ P P QP Q PP Q VA G
Sbjct: 481 LQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQ-QPASQAAPPTQGQGRQSRPVAGG 539
Query: 115 PGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPG-----APPPTP 169
PG P + PPAS S P S GP PP + APPG PP P
Sbjct: 540 PGAPP--AARPPASPSPQRQAGPPQATRQTSVSGPA---PPKASGAPPGGQQRQGPPQKP 594
Query: 170 PSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGG---PKGGKMPGGPKPGGGPGLST 226
P PT GP P P P GPGP G P+ + P P P +
Sbjct: 595 PGPAGPTRQASQAGPVPRTGPPTTQQPRP-SGPGPAGRPKPQLAQKPSQDVP--PPATAA 651
Query: 227 PGGHPKP 233
GG P P
Sbjct: 652 AGGPPHP 658
Score = 86.3 bits (212), Expect = 9e-17
Identities = 75/228 (32%), Positives = 84/228 (36%), Gaps = 38/228 (16%)
Query: 32 RSPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQ-----PPPQQPPPQQPPPHQ 86
R PP G GP PGPG PP+ PP Q QQ PP P PQ+ P
Sbjct: 460 RPPPQG-------GPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPT 512
Query: 87 PPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSS---------------- 130
P QP Q PP Q VA GPG P + PPAS S
Sbjct: 513 SAPQ-QPASQAAPPTQGQGRQSRPVAGGPGAPPA--ARPPASPSPQRQAGPPQATRQTSV 569
Query: 131 APPATPPTSGAPPGS----GPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTP-PQAGGPP 185
+ PA P SGAPPG GP P P T A P P +G PTT P+ GP
Sbjct: 570 SGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPV--PRTGPPTTQQPRPSGPG 627
Query: 186 PPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKP 233
P P P Q P P P+ L+ P+P
Sbjct: 628 PAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLNKSQSLTNAFNLPEP 675
Score = 56.2 bits (134), Expect = 1e-07
Identities = 55/168 (32%), Positives = 62/168 (36%), Gaps = 27/168 (16%)
Query: 13 GGGFHRRGGGGGRGGLHDFRSPPPGMGLNQNRGPMGPG--PGQSGPKPP-IPPPPPHQQQ 69
G G R GG G R PP + GP SGP PP PP QQ
Sbjct: 528 GQGRQSRPVAGGPGAPPAAR-PPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQ 586
Query: 70 QQPPPQQPPPQQPPPHQ-----PPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPA--PGVG 122
+Q PPQ+PP P Q P P P QQP P GPGPA P
Sbjct: 587 RQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRP-----------SGPGPAGRPKPQ 635
Query: 123 SAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPP 170
A S PP +G P P P ++T+A P P PP
Sbjct: 636 LAQKPSQDVPPPATAAAGGP----PHPQLNKSQSLTNA-FNLPEPAPP 678
Score = 52.4 bits (124), Expect = 1e-06
Identities = 57/188 (30%), Positives = 64/188 (34%), Gaps = 68/188 (36%)
Query: 141 APPGSGP-GPTPTP---------------PPAVTSAPP-GAPP---PTPPSSGVP--TTP 178
A PG G G TP+P PPA PP G PP P P G P P
Sbjct: 426 ASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRP 485
Query: 179 PQAG-------GPP---PPPAAVPGPGPGPKQ-------------------GPGPGGPKG 209
P G GPP P P +P P P+Q GPG P
Sbjct: 486 PPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPA 545
Query: 210 GKMPGGPKP---GGGPGLS--TPGGHPKPPHRGGGEPRGGRQHHPPYHQQHHQGPP--PG 262
+ P P P G P + T P PP G P G Q QGPP P
Sbjct: 546 ARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGG----------QQRQGPPQKPP 595
Query: 263 GPGGRSEE 270
GP G + +
Sbjct: 596 GPAGPTRQ 603
Score = 41.2 bits (95), Expect = 0.003
Identities = 22/54 (40%), Positives = 29/54 (53%), Gaps = 6/54 (11%)
Query: 95 QQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATP--PTSGAPPGSG 146
Q+ QPPPPP + P G P PG +A +S AP A+P P+ G+ G G
Sbjct: 26 QRPQPPPPPPGAHSP----GATPGPGTATAERSSGVAPAASPAAPSPGSSGGGG 75
Score = 33.5 bits (75), Expect = 0.70
Identities = 18/53 (33%), Positives = 18/53 (33%)
Query: 177 TPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGG 229
T Q PPPPP PG P G G P PG S GG
Sbjct: 23 TDLQRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSGGGG 75
Score = 31.2 bits (69), Expect = 3.5
Identities = 16/43 (37%), Positives = 19/43 (44%), Gaps = 2/43 (4%)
Query: 133 PATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPP--PTPPSSG 173
P PP PG+ PGP + P A P P+P SSG
Sbjct: 30 PPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSG 72
Score = 30.4 bits (67), Expect = 5.9
Identities = 16/47 (34%), Positives = 18/47 (38%), Gaps = 5/47 (10%)
Query: 149 PTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPG 195
P P PPP +P P P G T +G P A P PG
Sbjct: 28 PQPPPPPPGAHSPGATPGP-----GTATAERSSGVAPAASPAAPSPG 69
>gi|19924097 synapsin I isoform Ib [Homo sapiens]
Length = 669
Score = 110 bits (274), Expect = 6e-24
Identities = 79/240 (32%), Positives = 94/240 (39%), Gaps = 29/240 (12%)
Query: 42 QNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPP 101
Q + PG G G P P +Q Q P P Q+PPP PP P P Q+Q PP
Sbjct: 421 QRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPP 480
Query: 102 ----PPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAV 157
PP + + GP + P+ +SA P P + APP G G P
Sbjct: 481 LQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSA-PQQPASQAAPPTQGQGRQSRPVAGG 539
Query: 158 TSAPPGAPPPTPPSSGVPTTPPQA------GGPPPPPAAVPGPGPGPKQG-----PGPGG 206
APP A PP PS PPQA GP PP A+ PG +QG PGP G
Sbjct: 540 PGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAG 599
Query: 207 PKGGKMPGGPKPGGGPGLST--------PGGHPKP-----PHRGGGEPRGGRQHHPPYHQ 253
P GP P GP + P G PKP P + P PP+ Q
Sbjct: 600 PTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQ 659
Score = 91.3 bits (225), Expect = 3e-18
Identities = 81/247 (32%), Positives = 94/247 (38%), Gaps = 42/247 (17%)
Query: 18 RRGGGGGRGGLHDFRSPPPG---MGLNQNRGPMGP----------GPGQSGP-----KPP 59
+R GRG ++P PG +G ++ P GP GP Q GP PP
Sbjct: 423 QRDASPGRGS--HGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPP 480
Query: 60 IPPPPPHQQQQQ-----PPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQG 114
+ PP Q QQ PP P PQ+ P P QP Q PP Q VA G
Sbjct: 481 LQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQ-QPASQAAPPTQGQGRQSRPVAGG 539
Query: 115 PGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPG-----APPPTP 169
PG P + PPAS S P S GP PP + APPG PP P
Sbjct: 540 PGAPP--AARPPASPSPQRQAGPPQATRQTSVSGPA---PPKASGAPPGGQQRQGPPQKP 594
Query: 170 PSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGG---PKGGKMPGGPKPGGGPGLST 226
P PT GP P P P GPGP G P+ + P P P +
Sbjct: 595 PGPAGPTRQASQAGPVPRTGPPTTQQPRP-SGPGPAGRPKPQLAQKPSQDVP--PPATAA 651
Query: 227 PGGHPKP 233
GG P P
Sbjct: 652 AGGPPHP 658
Score = 86.3 bits (212), Expect = 9e-17
Identities = 74/222 (33%), Positives = 82/222 (36%), Gaps = 38/222 (17%)
Query: 32 RSPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQ-----PPPQQPPPQQPPPHQ 86
R PP G GP PGPG PP+ PP Q QQ PP P PQ+ P
Sbjct: 460 RPPPQG-------GPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPT 512
Query: 87 PPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSS---------------- 130
P QP Q PP Q VA GPG P + PPAS S
Sbjct: 513 SAPQ-QPASQAAPPTQGQGRQSRPVAGGPGAPPA--ARPPASPSPQRQAGPPQATRQTSV 569
Query: 131 APPATPPTSGAPPGS----GPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTP-PQAGGPP 185
+ PA P SGAPPG GP P P T A P P +G PTT P+ GP
Sbjct: 570 SGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPV--PRTGPPTTQQPRPSGPG 627
Query: 186 PPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTP 227
P P P Q P P P+ P + P
Sbjct: 628 PAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLKASPAQAQP 669
Score = 52.4 bits (124), Expect = 1e-06
Identities = 57/188 (30%), Positives = 64/188 (34%), Gaps = 68/188 (36%)
Query: 141 APPGSGP-GPTPTP---------------PPAVTSAPP-GAPP---PTPPSSGVP--TTP 178
A PG G G TP+P PPA PP G PP P P G P P
Sbjct: 426 ASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRP 485
Query: 179 PQAG-------GPP---PPPAAVPGPGPGPKQ-------------------GPGPGGPKG 209
P G GPP P P +P P P+Q GPG P
Sbjct: 486 PPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPA 545
Query: 210 GKMPGGPKP---GGGPGLS--TPGGHPKPPHRGGGEPRGGRQHHPPYHQQHHQGPP--PG 262
+ P P P G P + T P PP G P G Q QGPP P
Sbjct: 546 ARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGG----------QQRQGPPQKPP 595
Query: 263 GPGGRSEE 270
GP G + +
Sbjct: 596 GPAGPTRQ 603
Score = 41.2 bits (95), Expect = 0.003
Identities = 22/54 (40%), Positives = 29/54 (53%), Gaps = 6/54 (11%)
Query: 95 QQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATP--PTSGAPPGSG 146
Q+ QPPPPP + P G P PG +A +S AP A+P P+ G+ G G
Sbjct: 26 QRPQPPPPPPGAHSP----GATPGPGTATAERSSGVAPAASPAAPSPGSSGGGG 75
Score = 33.5 bits (75), Expect = 0.70
Identities = 18/53 (33%), Positives = 18/53 (33%)
Query: 177 TPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGG 229
T Q PPPPP PG P G G P PG S GG
Sbjct: 23 TDLQRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSGGGG 75
Score = 31.2 bits (69), Expect = 3.5
Identities = 16/43 (37%), Positives = 19/43 (44%), Gaps = 2/43 (4%)
Query: 133 PATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPP--PTPPSSG 173
P PP PG+ PGP + P A P P+P SSG
Sbjct: 30 PPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSG 72
Score = 30.4 bits (67), Expect = 5.9
Identities = 16/47 (34%), Positives = 18/47 (38%), Gaps = 5/47 (10%)
Query: 149 PTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPG 195
P P PPP +P P P G T +G P A P PG
Sbjct: 28 PQPPPPPPGAHSPGATPGP-----GTATAERSSGVAPAASPAAPSPG 69
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 109 bits (273), Expect = 8e-24
Identities = 75/200 (37%), Positives = 86/200 (43%), Gaps = 22/200 (11%)
Query: 49 PGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSK 108
P P PP PP P PPP P PP PPP PPPPP
Sbjct: 565 PSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPP---------PPPPPPLPGG 615
Query: 109 PVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPT 168
++ P G +PP S PP P G G P+P+ P T+ PP PPP
Sbjct: 616 VCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGI-PSPSSLPGGTAIPP--PPPL 672
Query: 169 PPSSGVPTTPPQ---AGGPPPPPAAVPG-PGPGPKQGPGPGGPKGGKMPGGPKPGGGPGL 224
P S+ +P PP + G PPPP +PG G P P PGGP G P P P GGPG+
Sbjct: 673 PGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGP--GIPPPPPFP-GGPGI 729
Query: 225 STPG---GHPKPPHRGGGEP 241
P G P PP G G P
Sbjct: 730 PPPPPGMGMPPPPPFGFGVP 749
Score = 81.6 bits (200), Expect = 2e-15
Identities = 58/163 (35%), Positives = 65/163 (39%), Gaps = 35/163 (21%)
Query: 34 PPPGM--GLNQNRGPMGPGPGQSGPKPP------IPPPPPHQQQQQPPPQQPPPQQPPPH 85
PPP + G+ + P PG P PP IPPPPP + P P
Sbjct: 608 PPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIP--SPSSLPGGTA 665
Query: 86 QPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGS 145
PPP P P + PPPPP P PG PP PP P +G P
Sbjct: 666 IPPPPPLPGSARIPPPPP-------------PLPGSAGIPP----PPPPLPGEAGMP--- 705
Query: 146 GPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPP 188
P P P P PP PPP P G+P PP G PPPPP
Sbjct: 706 ---PPPPPLPGGPGIPP--PPPFPGGPGIPPPPPGMGMPPPPP 743
Score = 71.2 bits (173), Expect = 3e-12
Identities = 54/162 (33%), Positives = 59/162 (36%), Gaps = 40/162 (24%)
Query: 33 SPPPGMGLNQNRGPMGPGPGQSGPKPP--------IPPPPPHQQQQQPPPQQPPPQQPPP 84
SPPP + + P P P G P IPPPPP + PP PP
Sbjct: 631 SPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAG 690
Query: 85 HQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPG 144
PPP P P + PPPPP P PG PP PP P G PP
Sbjct: 691 IPPPPPPLPGEAGMPPPPP-------------PLPGGPGIPP-----PPPFPGGPGIPP- 731
Query: 145 SGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPP 186
PPP + G PPP P GVP P G P
Sbjct: 732 --------PPPGM-----GMPPPPPFGFGVPAAPVLPFGLTP 760
Score = 70.9 bits (172), Expect = 4e-12
Identities = 64/188 (34%), Positives = 75/188 (39%), Gaps = 45/188 (23%)
Query: 105 DSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSG-----APPGSGPGPTPTPPPAVTS 159
+ +K +A A V + P+ + PPA PP G PP PG + TPPP
Sbjct: 547 EDAKKEMASLSAAAITVPPSVPSRAPVPPA-PPLPGDSGTIIPPPPAPGDSTTPPPP--- 602
Query: 160 APPGAPPPTPPSSGV-----PTTPPQAGGPPPPP----AAVPGPGPGPKQGPGPGGPKGG 210
PP PPP P GV P+ P PPPP A +P P P P+ G G P
Sbjct: 603 -PPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPE---GVGIPSPS 658
Query: 211 KMPGG-------PKPGGG------PGLSTPGGHPKPPHRGGGEPRGGRQHHPPYHQQHHQ 257
+PGG P PG P L G P PP GE G PP
Sbjct: 659 SLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGE--AGMPPPPP------- 709
Query: 258 GPPPGGPG 265
P PGGPG
Sbjct: 710 -PLPGGPG 716
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 109 bits (273), Expect = 8e-24
Identities = 75/200 (37%), Positives = 86/200 (43%), Gaps = 22/200 (11%)
Query: 49 PGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSK 108
P P PP PP P PPP P PP PPP PPPPP
Sbjct: 574 PSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPP---------PPPPPPLPGG 624
Query: 109 PVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPT 168
++ P G +PP S PP P G G P+P+ P T+ PP PPP
Sbjct: 625 VCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGI-PSPSSLPGGTAIPP--PPPL 681
Query: 169 PPSSGVPTTPPQ---AGGPPPPPAAVPG-PGPGPKQGPGPGGPKGGKMPGGPKPGGGPGL 224
P S+ +P PP + G PPPP +PG G P P PGGP G P P P GGPG+
Sbjct: 682 PGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGP--GIPPPPPFP-GGPGI 738
Query: 225 STPG---GHPKPPHRGGGEP 241
P G P PP G G P
Sbjct: 739 PPPPPGMGMPPPPPFGFGVP 758
Score = 81.6 bits (200), Expect = 2e-15
Identities = 58/163 (35%), Positives = 65/163 (39%), Gaps = 35/163 (21%)
Query: 34 PPPGM--GLNQNRGPMGPGPGQSGPKPP------IPPPPPHQQQQQPPPQQPPPQQPPPH 85
PPP + G+ + P PG P PP IPPPPP + P P
Sbjct: 617 PPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIP--SPSSLPGGTA 674
Query: 86 QPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGS 145
PPP P P + PPPPP P PG PP PP P +G P
Sbjct: 675 IPPPPPLPGSARIPPPPP-------------PLPGSAGIPP----PPPPLPGEAGMP--- 714
Query: 146 GPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPP 188
P P P P PP PPP P G+P PP G PPPPP
Sbjct: 715 ---PPPPPLPGGPGIPP--PPPFPGGPGIPPPPPGMGMPPPPP 752
Score = 71.2 bits (173), Expect = 3e-12
Identities = 54/162 (33%), Positives = 59/162 (36%), Gaps = 40/162 (24%)
Query: 33 SPPPGMGLNQNRGPMGPGPGQSGPKPP--------IPPPPPHQQQQQPPPQQPPPQQPPP 84
SPPP + + P P P G P IPPPPP + PP PP
Sbjct: 640 SPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAG 699
Query: 85 HQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPG 144
PPP P P + PPPPP P PG PP PP P G PP
Sbjct: 700 IPPPPPPLPGEAGMPPPPP-------------PLPGGPGIPP-----PPPFPGGPGIPP- 740
Query: 145 SGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPP 186
PPP + G PPP P GVP P G P
Sbjct: 741 --------PPPGM-----GMPPPPPFGFGVPAAPVLPFGLTP 769
Score = 70.9 bits (172), Expect = 4e-12
Identities = 64/188 (34%), Positives = 75/188 (39%), Gaps = 45/188 (23%)
Query: 105 DSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSG-----APPGSGPGPTPTPPPAVTS 159
+ +K +A A V + P+ + PPA PP G PP PG + TPPP
Sbjct: 556 EDAKKEMASLSAAAITVPPSVPSRAPVPPA-PPLPGDSGTIIPPPPAPGDSTTPPPP--- 611
Query: 160 APPGAPPPTPPSSGV-----PTTPPQAGGPPPPP----AAVPGPGPGPKQGPGPGGPKGG 210
PP PPP P GV P+ P PPPP A +P P P P+ G G P
Sbjct: 612 -PPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPE---GVGIPSPS 667
Query: 211 KMPGG-------PKPGGG------PGLSTPGGHPKPPHRGGGEPRGGRQHHPPYHQQHHQ 257
+PGG P PG P L G P PP GE G PP
Sbjct: 668 SLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGE--AGMPPPPP------- 718
Query: 258 GPPPGGPG 265
P PGGPG
Sbjct: 719 -PLPGGPG 725
>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
Length = 639
Score = 109 bits (272), Expect = 1e-23
Identities = 88/264 (33%), Positives = 98/264 (37%), Gaps = 70/264 (26%)
Query: 15 GFHRRGGGGGRGGLHDFRSPPPGMGLNQNRGPMGPGPGQSGPKPPI--PPPPPHQQQQQP 72
G H G GG GG H F P P + PM P +GP PP PPPPP Q P
Sbjct: 381 GMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNP--NGPPPPWMQPPPPPMNQGPHP 438
Query: 73 PPQQ------------------------------------PPPQQPPPHQPPPHP----- 91
P PPP PP QPPP P
Sbjct: 439 PGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLP 498
Query: 92 --QPHQQQQPPPPPQDSSKPVVAQGPGP----------APGVGSAPP-----ASSSAPPA 134
Q QQQ PPPPP SS + + P P + G GS PP A+++A P
Sbjct: 499 PWQQQQQQPPPPPPPSSS--MASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPG 556
Query: 135 TPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGP 194
P G P P P PP APP PPP P S+G+ PP PPPPP P
Sbjct: 557 APQMQGNPT-MVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMYAPP----PPPPPPMDPS- 610
Query: 195 GPGPKQGPGPGGPKGGKMPGGPKP 218
G G G MP P P
Sbjct: 611 NFVTMMGMGVAGMPPFGMPPAPPP 634
Score = 66.6 bits (161), Expect = 7e-11
Identities = 64/202 (31%), Positives = 71/202 (35%), Gaps = 36/202 (17%)
Query: 72 PPPQQPPPQQPPPHQPPPHPQPHQQQQPP---PPPQDSSKPVVAQGPGPAPGVGSAPPAS 128
P P P P + PPP Q +PP P +S G GP G G P
Sbjct: 339 PLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPG-GPGGGP--- 394
Query: 129 SSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPP 188
S P P +G G P PP PP PP PP + P PP GPPP
Sbjct: 395 HSFPHPLPSLTGGHGGHPMQHNPNGPP-----PPWMQPPPPPMNQGP-HPPGHHGPPPMD 448
Query: 189 AAVPGPGPGP-----KQGPG-PGGPKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGGGEPR 242
+ G QG G P G MP P P P G P PP G
Sbjct: 449 QYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPP--------PSGQPPPPPSG----- 495
Query: 243 GGRQHHPPYHQQHHQGPPPGGP 264
PP+ QQ Q PPP P
Sbjct: 496 ----PLPPWQQQQQQPPPPPPP 513
Score = 66.2 bits (160), Expect = 1e-10
Identities = 58/190 (30%), Positives = 67/190 (35%), Gaps = 29/190 (15%)
Query: 91 PQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSG------APPG 144
P+P PPPP S S PP +S P + P G PG
Sbjct: 344 PRPAAPANNPPPPSLMST------------TQSRPPWMNSGPSESRPYHGMHGGGPGGPG 391
Query: 145 SGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGP 204
GP P P P++T G P P+ PP PPPP GP P GP P
Sbjct: 392 GGPHSFPHPLPSLTGGHGGHPMQHNPNG-----PPPPWMQPPPPPMNQGPHPPGHHGPPP 446
Query: 205 GGPKGGKMPGGP---KPGGGPGLSTP---GGHPKPPHRGGGEPRGGRQHHPPYHQQHHQG 258
G P G + G G+ P G P PP G+P P QQ Q
Sbjct: 447 MDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQ 506
Query: 259 PPPGGPGGRS 268
PPP P S
Sbjct: 507 PPPPPPPSSS 516
Score = 58.5 bits (140), Expect = 2e-08
Identities = 37/95 (38%), Positives = 39/95 (41%), Gaps = 18/95 (18%)
Query: 49 PGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPP------HQPPPHPQPHQQQQPPPP 102
PG Q P + P PP Q PP PPP PPP + PPP PPPP
Sbjct: 555 PGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMYAPPP---------PPPP 605
Query: 103 PQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPP 137
P D S V G G A G P APP PP
Sbjct: 606 PMDPSNFVTMMGMGVA---GMPPFGMPPAPPPPPP 637
Score = 53.1 bits (126), Expect = 8e-07
Identities = 42/126 (33%), Positives = 46/126 (36%), Gaps = 21/126 (16%)
Query: 145 SGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGP 204
SGP TP +AP PPP S + PP P G G GP
Sbjct: 333 SGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHG-----MHGGGP 387
Query: 205 GGPKGG---------KMPGGPKPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHPPYHQQH 255
GGP GG + GG GG P P G P PP P + HPP
Sbjct: 388 GGPGGGPHSFPHPLPSLTGG--HGGHPMQHNPNG-PPPPWMQPPPPPMNQGPHPP----G 440
Query: 256 HQGPPP 261
H GPPP
Sbjct: 441 HHGPPP 446
>gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3
[Homo sapiens]
Length = 1125
Score = 107 bits (268), Expect = 3e-23
Identities = 92/271 (33%), Positives = 107/271 (39%), Gaps = 39/271 (14%)
Query: 35 PPGMGLNQNRG---PMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHP 91
PP +G Q P+G P GP P PPPPP + P PP PP PPP
Sbjct: 689 PPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPIT 748
Query: 92 QPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPP-------- 143
P PP P S +V+ G A S S+ PPA P PP
Sbjct: 749 PP-VSIPPPHTPPISIPNLVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLL 807
Query: 144 ---GSGPGPT---PTPPPAVTSAPPGAPP-------PTPPSSGVPTTPPQAGGPPPPPAA 190
G PGP P + A PG P P P P PP+ P PP
Sbjct: 808 GTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPR----PMPPHM 863
Query: 191 V---PGPGPGPKQGPGPGGPKGGKMPGGP--KPGGGPGLSTPGGHPKPPHRGGGEPRGGR 245
+ P PGPG P P G KG P GP +PGG PGL PG P GG E R GR
Sbjct: 864 MHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPG-----PGPGGPEDRDGR 918
Query: 246 QHHPPYHQQHHQGPPPGGPGGRSEEKISDSE 276
Q P QQ Q P P + +++ S+
Sbjct: 919 QQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQ 949
Score = 60.1 bits (144), Expect = 7e-09
Identities = 38/118 (32%), Positives = 46/118 (38%), Gaps = 6/118 (5%)
Query: 83 PPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATP-----P 137
P +PP P PH Q+ P PP+ ++ +GP P PG + PP P P
Sbjct: 836 PLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVR 895
Query: 138 TSGAPPGSGPGPTP-TPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGP 194
G P GPGP P P P P P P P Q PPP+ P P
Sbjct: 896 PGGMPGLGGPGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPP 953
Score = 59.3 bits (142), Expect = 1e-08
Identities = 44/99 (44%), Positives = 46/99 (46%), Gaps = 14/99 (14%)
Query: 19 RGGGGGRGGLHDFRSPPP-GM-GLNQNRGPM---GPGPGQSGPKPPIPPPPPHQQQQQPP 73
RG G GG F PPP GM G GP G PG GP P P +QQPP
Sbjct: 866 RGPPPGPGG---FAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQQPP 922
Query: 74 PQQPPPQQPPPHQPPPHPQPHQQQQPPP---PPQDSSKP 109
Q PQQ P Q P PQ QQQQPPP PP +P
Sbjct: 923 QQ---PQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQP 958
Score = 52.4 bits (124), Expect = 1e-06
Identities = 44/112 (39%), Positives = 47/112 (41%), Gaps = 16/112 (14%)
Query: 135 TPPTSGAPPGSGPGPTPTPP---PA-VTSAPPGAPP--PTPPSSGV---PTTPPQAGGPP 185
T P S P P P P PP PA +T PP PP P PP G P P G PP
Sbjct: 652 TEPVSPIPK---PLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLGIPP 708
Query: 186 P--PPAAVPGPGPGPKQGPG--PGGPKGGKMPGGPKPGGGPGLSTPGGHPKP 233
P P P P P P PG P G +P GP P P +S P H P
Sbjct: 709 PGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPP 760
Score = 52.0 bits (123), Expect = 2e-06
Identities = 35/87 (40%), Positives = 40/87 (45%), Gaps = 12/87 (13%)
Query: 14 GGFHRRGGGGGRGGLHDFRSPPPGMGLNQNRG--PMGPGPGQSGPKPPIPPPPPHQQQQQ 71
G F R GG G GG P PG G ++R P Q P+P P P QQQQQ
Sbjct: 891 GPFVRPGGMPGLGG------PGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQ 944
Query: 72 PPPQQPPPQQPPPHQPPPHPQPHQQQQ 98
PPP QQPPP Q P + +Q
Sbjct: 945 PPPS----QQPPPTQQQPQQFRNDNRQ 967
Score = 50.4 bits (119), Expect = 6e-06
Identities = 62/258 (24%), Positives = 79/258 (30%), Gaps = 62/258 (24%)
Query: 62 PPPPHQQQQQPPPQQPPPQQPPPHQPPPHP------------------QPHQQQQPPPPP 103
PPPP + +PP Q P P Q P Q Q Q PP P
Sbjct: 155 PPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQLQQILQTFQQPPKP 214
Query: 104 QDSS--KPVVAQGPGPAPGVGSAPPASSSAPPATPPTS----------------GAPPGS 145
Q + V+AQ + + P S A PP P
Sbjct: 215 QSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPEAV 274
Query: 146 GPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQ----- 200
T+AP A PP P ++ P A PPPP A PG G +Q
Sbjct: 275 EESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQ 334
Query: 201 -------GPGPGGPKGGKM-------PGGPKPGGG-------PGLSTPGGHPKPPHRGGG 239
P G + M P G PG G P ++ P P PP +
Sbjct: 335 HQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQPF 394
Query: 240 EPRGGRQHHPPYHQQHHQ 257
+ Q+ P + H Q
Sbjct: 395 QASFQAQNEPLTQKPHQQ 412
Score = 43.5 bits (101), Expect = 7e-04
Identities = 49/154 (31%), Positives = 54/154 (35%), Gaps = 20/154 (12%)
Query: 126 PASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPP 185
P + A TS P S P P P P P P P P P + P PP GPP
Sbjct: 637 PENEVAQNGGAETSHTEPVS-PIPKPLPVPV-----PPIPVPAPITVPPPQVPPHQPGPP 690
Query: 186 PPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPK--PPHRGGGEPRG 243
A P P P G P G PG P P P PG +P PP G P G
Sbjct: 691 VVGALQP-----PAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPP---GFLPPG 742
Query: 244 GRQHHPPYHQQHHQGPPPGGPGGRSEEKISDSEG 277
PP PPP P +S + G
Sbjct: 743 ----PPPPITPPVSIPPPHTPPISIPNLVSGARG 772
Score = 33.1 bits (74), Expect = 0.91
Identities = 30/112 (26%), Positives = 34/112 (30%), Gaps = 24/112 (21%)
Query: 54 SGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPP----------PHPQPHQQQQPPPP- 102
+ P +PP P P P PPP Q P P HQ P
Sbjct: 288 TAPAAAVPPAPT---ATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPR 344
Query: 103 -------PQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGP 147
P P+ G P G+ PP A P PPT PP P
Sbjct: 345 MMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPT---PPVQQP 393
Score = 32.0 bits (71), Expect = 2.0
Identities = 23/77 (29%), Positives = 29/77 (37%), Gaps = 8/77 (10%)
Query: 35 PPGMGLNQN----RGPMGPGPGQSG----PKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQ 86
P MG+ Q+ + P+ P G P PP PP PP QQP
Sbjct: 343 PRMMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQPFQASFQAQN 402
Query: 87 PPPHPQPHQQQQPPPPP 103
P +PHQQ+ P
Sbjct: 403 EPLTQKPHQQEMEVEQP 419
Score = 31.6 bits (70), Expect = 2.6
Identities = 27/75 (36%), Positives = 31/75 (41%), Gaps = 14/75 (18%)
Query: 29 HDFRSPP----PGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPP 84
H PP PG GL P P P + +P IPP PP QQ P Q Q P
Sbjct: 355 HQVPLPPNGQMPGFGLL----PTPPFPPMA--QPVIPPTPPVQQ----PFQASFQAQNEP 404
Query: 85 HQPPPHPQPHQQQQP 99
PH Q + +QP
Sbjct: 405 LTQKPHQQEMEVEQP 419
Score = 31.2 bits (69), Expect = 3.5
Identities = 36/161 (22%), Positives = 62/161 (38%), Gaps = 28/161 (17%)
Query: 460 PEKLAQKNPMYQKERETPPRFAQHGT------FEYEYSQRWKSLDEMEKQQREQVEKNMK 513
P+ A + P Q++++ PP T F + Q++ S + E+ R ++
Sbjct: 929 PQPQAPQQPQQQQQQQPPPSQQPPPTQQQPQQFRNDNRQQFNSGRDQERFGRRSFGNRVE 988
Query: 514 DAKDKLESEMEDAYHEHQANLLRQDLMRRQEELRRMEELHNQEMQKRKEMQLRQEEERRR 573
+ +++ + +D +N R++ RR + R +L EER R
Sbjct: 989 NDRERYGNRNDD---RDNSNRDRREWGRRSPDRDRHRDL----------------EERNR 1029
Query: 574 REEEMMIRQREMEEQMRRQREESYSRMGYMDPRERDMRMGG 614
R R RE + + R R E G P D R GG
Sbjct: 1030 RSSGH--RDRERDSRDRESRREKEEARGKEKPEVTD-RAGG 1067
Score = 30.0 bits (66), Expect = 7.7
Identities = 30/108 (27%), Positives = 38/108 (35%), Gaps = 27/108 (25%)
Query: 599 RMGYMDPRERDMRMGGGGAMNMGDPYGSGGQKFPPLGGGGGIGYEANPGVPPATMSGSMM 658
R M PR M M+ G P G GG PP G G P V P M G
Sbjct: 850 RFPLMPPRPMPPHM-----MHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPG--- 901
Query: 659 GSDMRTERFGQGGAGPVGGQGPRGMGPGTPAGYGRGREEYEGPNKKPR 706
+GG GP GPG P ++ + P ++P+
Sbjct: 902 ----------------LGGPGP---GPGGPEDRDGRQQPPQQPQQQPQ 930
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 105 bits (262), Expect = 1e-22
Identities = 79/231 (34%), Positives = 88/231 (38%), Gaps = 35/231 (15%)
Query: 34 PPPGMG-LNQNRGPMGPGPGQSGPKPPIP-------PPPPHQQQQQPPPQQPPPQQPPP- 84
PPP + + P+ P KPP+ PP P P Q PPP P P
Sbjct: 351 PPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPV 410
Query: 85 HQPPPHPQPHQQQQPPPPPQD-----SSKPVVAQGPG----------PAPGVGSAPPASS 129
HQPPP P + PPPPP S+ G G P G+ PPA
Sbjct: 411 HQPPPLPH----RPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYG 466
Query: 130 SAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPP--QAGGPPPP 187
PPA P P P P PPP + PP PPPTP G P PP PPPP
Sbjct: 467 --PPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTP---GYPPPPPTYNPNFPPPP 521
Query: 188 PAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGG 238
P P P PG G P P PGG P + P P P GG
Sbjct: 522 PRLPPTHAVPPHPPPGLGLPPASYPPPAVPPGGQPPVPPPIPPPGMPPVGG 572
Score = 73.9 bits (180), Expect = 5e-13
Identities = 91/285 (31%), Positives = 97/285 (34%), Gaps = 88/285 (30%)
Query: 57 KPPIPPPPPHQQQQ----QPPPQQPPPQQPPPHQ--PPPHP------QPHQQQQP----- 99
K +P PHQ QQ QP PQ P QQ P Q P P QP QQQQP
Sbjct: 262 KQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPK 321
Query: 100 PPPPQDSS----KPVVAQGP--------GPAPGVGSAPPASSSAPPATPPTSGAPP---- 143
P PQ SS K V P P P + PPA PP PP
Sbjct: 322 KPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAA 381
Query: 144 ---GSGPGPTPT--------PPPA----VTSAP--PGAPPPTPPSS---GVPTTP----- 178
PGP PPPA V P P PPP PPSS G+ TT
Sbjct: 382 LGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSG 441
Query: 179 --------------PQAGGPPP---PPAAVPGP----GPGPKQGPGPGGPKGGKMPGGPK 217
P G PP PPA +P P P P P P P P
Sbjct: 442 EGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPP 501
Query: 218 PGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHPPYHQQHHQGPPPG 262
P TPG P PP P + P + H PPPG
Sbjct: 502 P-------TPGYPPPPPTYNPNFPPPPPRLPPTHAVPPH--PPPG 537
Score = 70.5 bits (171), Expect = 5e-12
Identities = 70/238 (29%), Positives = 80/238 (33%), Gaps = 45/238 (18%)
Query: 51 PGQSGPKPPIPPPP--PHQQQQQPPPQQPP--PQQPPPHQPPPHPQPHQQQQPPPPPQDS 106
P Q P + P P P QQ QP P PQQ P QP QP QQ + P P S
Sbjct: 270 PHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSS 329
Query: 107 SKPV---VAQGPG--------PAPGVGSAPPASSSAPPATPPTSGAPP-------GSGPG 148
+ V V P P P + PPA PP PP PG
Sbjct: 330 PRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPG 389
Query: 149 PTP-TPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAA-VPGPGPGPKQGPGPGG 206
P T P V PP P P +P P PPPPP++ + G G G
Sbjct: 390 PVDATDLPKVQIPPPAHPAPVHQPPPLPHRP-----PPPPPSSYMTGMSTTSSYMSGEGY 444
Query: 207 PKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHPPYHQQHHQGPPPGGP 264
M + T G P G P G H PYH + PP P
Sbjct: 445 QSLQSM-----------MKTEG-----PSYGALPPAYGPPAHLPYHPHVYPPNPPPPP 486
Score = 61.2 bits (147), Expect = 3e-09
Identities = 47/134 (35%), Positives = 50/134 (37%), Gaps = 45/134 (33%)
Query: 33 SPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQ 92
+PPP P P P S P P IPPP P PP P PPP PP H
Sbjct: 481 NPPP---------PPVPPPPASFPPPAIPPPTPGYPPP-PPTYNPNFPPPPPRLPPTHAV 530
Query: 93 PHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPT 152
P P PP PG+G PPA+ P PPG P P
Sbjct: 531 P-----PHPP----------------PGLG--------LPPASYPPPAVPPGGQP---PV 558
Query: 153 PPPAVTSAPPGAPP 166
PPP PPG PP
Sbjct: 559 PPPI---PPPGMPP 569
Score = 46.6 bits (109), Expect = 8e-05
Identities = 33/89 (37%), Positives = 36/89 (40%), Gaps = 20/89 (22%)
Query: 49 PGPGQSGPKPPIPPPPPHQQQQ--QPPPQQPP----PQQPPP-------HQPPPHPQPHQ 95
P P P P PPPPP PPP+ PP P PPP PPP P
Sbjct: 495 PPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASYPPPAVPP-- 552
Query: 96 QQQPPPPPQDSSKPVVAQGPGPAPGVGSA 124
QPP PP P+ G P G+G A
Sbjct: 553 GGQPPVPP-----PIPPPGMPPVGGLGRA 576
>gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
Length = 638
Score = 104 bits (260), Expect = 2e-22
Identities = 83/259 (32%), Positives = 94/259 (36%), Gaps = 75/259 (28%)
Query: 15 GFHRRGGGGGRGGLHDFRSPPPGMGLNQNRGPMGPGPGQSGPKPPI--PPPPPHQQQQQP 72
G H G GG GG H F P P + PM P +GP PP PPPPP Q P
Sbjct: 381 GMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNP--NGPPPPWMQPPPPPMNQGPHP 438
Query: 73 PPQQ------------------------------------PPPQQPPPHQPPPHP----- 91
P PPP PP QPPP P
Sbjct: 439 PGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLP 498
Query: 92 --QPHQQQQPPPPPQDSSKPVVAQGPGP----------APGVGSAPP-----ASSSAPPA 134
Q QQQ PPPPP SS + + P P + G GS PP A+++A P
Sbjct: 499 PWQQQQQQPPPPPPPSSS--MASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPG 556
Query: 135 TPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGP 194
P G P P PP PPGAPPP PP PP + G PP GP
Sbjct: 557 APQMQG-----NPTMVPLPPGVQPPLPPGAPPPPPP------PPPGSAGMMIPPRGGDGP 605
Query: 195 GPGPKQGPGPGGPKGGKMP 213
+ P P G+ P
Sbjct: 606 SHESEDFPRPLVTLPGRQP 624
Score = 67.8 bits (164), Expect = 3e-11
Identities = 58/187 (31%), Positives = 68/187 (36%), Gaps = 30/187 (16%)
Query: 91 PQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSG------APPG 144
P+P PPPP S S PP +S P + P G PG
Sbjct: 344 PRPAAPANNPPPPSLMST------------TQSRPPWMNSGPSESRPYHGMHGGGPGGPG 391
Query: 145 SGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGP 204
GP P P P++T G P P+ PP PPPP GP P GP P
Sbjct: 392 GGPHSFPHPLPSLTGGHGGHPMQHNPNG-----PPPPWMQPPPPPMNQGPHPPGHHGPPP 446
Query: 205 GGPKGGKMPGGP---KPGGGPGLSTP---GGHPKPPHRGGGEPRGGRQHH-PPYHQQHHQ 257
G P G + G G+ P G P PP G+P PP+ QQ Q
Sbjct: 447 MDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQ 506
Query: 258 GPPPGGP 264
PPP P
Sbjct: 507 PPPPPPP 513
Score = 62.4 bits (150), Expect = 1e-09
Identities = 55/174 (31%), Positives = 62/174 (35%), Gaps = 31/174 (17%)
Query: 22 GGGRGGLHDFRS--PPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPP 79
G G LH + PPP MG+ P P GQ P P P PP QQQQQPPP PP
Sbjct: 457 GSGVYRLHQGKGMMPPPPMGMMPPPPP--PPSGQPPPPPSGPLPPWQQQQQQPPPPPPPS 514
Query: 80 QQPPPHQPPPHPQ---------------PHQQQQ------PPPPPQDSSKPVVAQGPGPA 118
P P Q P QQQQ P P + +V PG
Sbjct: 515 SSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQ 574
Query: 119 PGVG-SAPPASSSAPPAT-----PPTSGAPPGSGPGPTPTPPPAVTSAPPGAPP 166
P + APP PP + PP G P P P + P P
Sbjct: 575 PPLPPGAPPPPPPPPPGSAGMMIPPRGGDGPSHESEDFPRPLVTLPGRQPQQRP 628
Score = 61.6 bits (148), Expect = 2e-09
Identities = 56/158 (35%), Positives = 66/158 (41%), Gaps = 31/158 (19%)
Query: 121 VGSAP-PAS--SSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPP--PTPPSSGVP 175
+G AP PAS S++ PAT P + AP + P P PPP++ S PP + PS P
Sbjct: 320 LGEAPVPASVGSTSGPATTPLASAPRPAAPANNP-PPPSLMSTTQSRPPWMNSGPSESRP 378
Query: 176 TTPPQAGGPPPPPAAVPGPGPGPKQGPGP-----GGPKGGKM---PGGPKPGGGPGLSTP 227
GGP GPG GP P P GG G M P GP P P +
Sbjct: 379 YHGMHGGGPG-------GPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPP---PWMQP- 427
Query: 228 GGHPKPPHRGGGEPRGGRQHHPPYHQQHHQGPPPGGPG 265
P PP G P G HH P + G P G G
Sbjct: 428 ---PPPPMNQGPHPPG---HHGPPPMDQYLGSTPVGSG 459
>gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo
sapiens]
Length = 247
Score = 104 bits (260), Expect = 2e-22
Identities = 80/228 (35%), Positives = 89/228 (39%), Gaps = 40/228 (17%)
Query: 46 PMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQD 105
P G P Q G +P PPPPP + PQ PPPQ Q PP P + +PP
Sbjct: 36 PEGRRP-QGGNQPQRPPPPPGK------PQGPPPQGGNQSQGPPPPPGKPEGRPPQGGNQ 88
Query: 106 SSKPVVAQGPGPAPGVGSAPP------ASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTS 159
S QGP P PG PP + + PP P P G P PPP
Sbjct: 89 S------QGPPPHPGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKPE 142
Query: 160 APPG-------APPPTPPSSGVPT-TPPQAGGPPPPPAAVPGPGPGPKQGPG--PGGPKG 209
PP PPP P G P PPQ G + PG GP Q G P GP
Sbjct: 143 RPPPQGGNQSQGPPPHP---GKPEGPPPQEGNKSRSARSPPGKPQGPPQQEGNKPQGPPP 199
Query: 210 GKMPGGPKPGGG-------PGLSTPGGHPKPPHRGGGEPRGGRQHHPP 250
P GP P GG P P G P PP +GG PR + PP
Sbjct: 200 PGKPQGPPPAGGNPQQPQAPPAGKPQG-PPPPPQGGRPPRPAQGQQPP 246
Score = 104 bits (259), Expect = 3e-22
Identities = 86/238 (36%), Positives = 100/238 (42%), Gaps = 45/238 (18%)
Query: 39 GLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQ 98
G + R P G G +PP PP P Q PPPQ Q PP PP P+
Sbjct: 34 GKPEGRRPQG---GNQPQRPPPPPGKP----QGPPPQGGNQSQGPP-PPPGKPEGR---- 81
Query: 99 PPPPPQDSSKPVVAQGPGPAPGVGS-APPASSSAPPATPPTSG---APPGSGPGPTPTPP 154
PPQ ++ +QGP P PG PP + TPP G PP G + PP
Sbjct: 82 ---PPQGGNQ---SQGPPPHPGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPP 135
Query: 155 PAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGP--GPKQGPG---PGGPKG 209
P PPG P PP G Q+ GPPP P GP P G K PG P+G
Sbjct: 136 P-----PPGKPERPPPQGG-----NQSQGPPPHPGKPEGPPPQEGNKSRSARSPPGKPQG 185
Query: 210 GKMPGGPKPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHPPYHQQHHQGPPPGGPGGR 267
G KP G P P G P+ P GG P+ + PP + QGPPP GGR
Sbjct: 186 PPQQEGNKPQGPP----PPGKPQGPPPAGGNPQ--QPQAPPAGKP--QGPPPPPQGGR 235
Score = 104 bits (259), Expect = 3e-22
Identities = 79/219 (36%), Positives = 91/219 (41%), Gaps = 44/219 (20%)
Query: 18 RRGGGGGRGGLHDFRSPPPGMGLNQNRGPMGPGPGQSGPKPP-----IPPPPPHQQQQQP 72
RR GG + + PPP G Q P G Q P PP PP +Q Q P
Sbjct: 39 RRPQGGNQP-----QRPPPPPGKPQGPPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPP 93
Query: 73 P----PQQPPPQ-------QPPPHQPPPHPQP---HQQQQPPPPPQDSSKPV-----VAQ 113
P P++PPPQ PPP P P P +Q +PPPPP +P +Q
Sbjct: 94 PHPGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKPERPPPQGGNQSQ 153
Query: 114 GPGPAPGVGSAPP---ASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPP 170
GP P PG PP + S +PP P G P PP PPG P PP
Sbjct: 154 GPPPHPGKPEGPPPQEGNKSRSARSPPGKPQGPPQQEGNKPQGPP-----PPGKPQGPPP 208
Query: 171 SSGVPTTP--PQAG---GPPPPPAAVPGPGPGPKQGPGP 204
+ G P P P AG GPPPPP G P P QG P
Sbjct: 209 AGGNPQQPQAPPAGKPQGPPPPPQG--GRPPRPAQGQQP 245
Score = 94.4 bits (233), Expect = 3e-19
Identities = 64/187 (34%), Positives = 75/187 (40%), Gaps = 32/187 (17%)
Query: 27 GLHDFRSPPPGMGLNQNRGPMGPGPGQSGP----KPPIPPP----------PPHQQQQQP 72
G + + PPP G + R P G Q P KP PPP PP + ++P
Sbjct: 64 GGNQSQGPPPPPGKPEGRPPQGGNQSQGPPPHPGKPERPPPQGGNQSQGTPPPPGKPERP 123
Query: 73 PPQ-------QPPPQQPPPHQPP------PHPQPHQQQQPPPPPQDSSKPVVAQGPGPAP 119
PPQ PPP P PP P PH + PPPQ+ +K A+ P P
Sbjct: 124 PPQGGNQSHRPPPPPGKPERPPPQGGNQSQGPPPHPGKPEGPPPQEGNKSRSARSP---P 180
Query: 120 GVGSAPPASSSAPPATPPTSGAPPGSGP-GPTPTPPPAVTSAPPGAPPPTPPSSGVPTTP 178
G PP P PP G P G P G P P A + P PPP PP G P P
Sbjct: 181 GKPQGPPQQEGNKPQGPPPPGKPQGPPPAGGNPQQPQAPPAGKPQGPPP-PPQGGRPPRP 239
Query: 179 PQAGGPP 185
Q PP
Sbjct: 240 AQGQQPP 246
Score = 55.5 bits (132), Expect = 2e-07
Identities = 39/130 (30%), Positives = 51/130 (39%), Gaps = 16/130 (12%)
Query: 157 VTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPG-GPKGGKMPGG 215
++ P G P P PP PPP GP P G G P+GG G
Sbjct: 32 ISGKPEGRRPQGGNQPQRPPPPPGKPQGPPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQG 91
Query: 216 PKPGGGPGLSTPGGHPKPPHRGGGEPRG-----GRQHHPP---YHQQHHQGPPPGGPGGR 267
P P PG +PP +GG + +G G+ PP +Q H PPPG P
Sbjct: 92 PPP-------HPGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKPERP 144
Query: 268 SEEKISDSEG 277
+ + S+G
Sbjct: 145 PPQGGNQSQG 154
Score = 32.0 bits (71), Expect = 2.0
Identities = 20/48 (41%), Positives = 23/48 (47%), Gaps = 8/48 (16%)
Query: 32 RSPPPGMGLNQNRGPMGPGPGQSGPKPPIPPP----PPHQQQQQPPPQ 75
+ PPP G Q P P G+ P+ P PPP PP Q Q PPQ
Sbjct: 204 QGPPPAGGNPQQ--PQAPPAGK--PQGPPPPPQGGRPPRPAQGQQPPQ 247
>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
Length = 464
Score = 104 bits (260), Expect = 2e-22
Identities = 92/244 (37%), Positives = 96/244 (39%), Gaps = 36/244 (14%)
Query: 46 PMGPGPGQSGPKPPIP---PPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPP-- 100
P GP PG P PP+ PP P + PPP PP P P PP P P PP
Sbjct: 224 PAGP-PGVKRPPPPLMNGLPPRPPLPESLPPP--PPGGLPLPPMPPTGPAPSGPPGPPQL 280
Query: 101 PPPQDSSKPVVAQGPGPAPGV-----GSAPPASSSAPPAT---PPTSGA-PPGSGPGPTP 151
PPP P PA GV G PPA PPA PPTSG PP G P
Sbjct: 281 PPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVHPPAPGVHP-- 338
Query: 152 TPPPAVTSAPPGAPPPT----PPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGP 207
P P V PG PP PP+ GV PP AG P P P Q PG P
Sbjct: 339 -PAPGVHPPAPGVHPPAPGVHPPAPGV-HPPPSAGVHPQAPGVHPAAPAVHPQAPGVHPP 396
Query: 208 KGGKMPGGP-----KPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHP-PYHQQHHQGPPP 261
G P P PG P S PG HP+PP G P H P P P
Sbjct: 397 APGMHPQAPGVHPQPPGVHP--SAPGVHPQPP---GVHPSNPGVHPPTPMPPMLRPPLPS 451
Query: 262 GGPG 265
GPG
Sbjct: 452 EGPG 455
Score = 78.6 bits (192), Expect = 2e-14
Identities = 82/220 (37%), Positives = 88/220 (40%), Gaps = 31/220 (14%)
Query: 34 PPPGMGLNQNRGPMGPGP-GQSGPKPPIPPPPPHQQQQQP---PPQQ---PP-----PQQ 81
PPPG P GP P G GP P +PPP P P PP PP P
Sbjct: 254 PPPGGLPLPPMPPTGPAPSGPPGP-PQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPA 312
Query: 82 PPPHQPPP--HPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTS 139
P H P P HP P PP P P V PAPGV PPA PPA P
Sbjct: 313 PGVHPPAPGVHP-PTSGVHPPAPGVHPPAPGVHP---PAPGV--HPPAPGVHPPA--PGV 364
Query: 140 GAPPGSGPGP-TPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPG- 197
PP +G P P PA + P AP PP+ G+ PQA G P P V PG
Sbjct: 365 HPPPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGM---HPQAPGVHPQPPGVHPSAPGV 421
Query: 198 PKQGPGPGGPKGGKMPGGPKPGG-GPGLST--PGGHPKPP 234
Q PG G P P P P L + PG P PP
Sbjct: 422 HPQPPGVHPSNPGVHPPTPMPPMLRPPLPSEGPGNIPPPP 461
Score = 75.9 bits (185), Expect = 1e-13
Identities = 63/183 (34%), Positives = 68/183 (37%), Gaps = 29/183 (15%)
Query: 34 PPPGMGLNQNR--------GPMGPGPGQSGPKPPIPPPPP--HQQQQQPPPQQPPPQQPP 83
PPP G++ G P PG P P + PP P H P P P
Sbjct: 281 PPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVHPPAPGVHPPA 340
Query: 84 PHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGP-APGVGSAPPA-SSSAPPATPPTSGA 141
P PP P H PP P + G P APGV A PA AP PP G
Sbjct: 341 PGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGM 400
Query: 142 PPGSGPGPTPTPPPAVTSAP-------------PGAPPPTP-PSSGVPTTPPQAGG--PP 185
P PG P PP SAP PG PPTP P P P + G PP
Sbjct: 401 HP-QAPGVHPQPPGVHPSAPGVHPQPPGVHPSNPGVHPPTPMPPMLRPPLPSEGPGNIPP 459
Query: 186 PPP 188
PPP
Sbjct: 460 PPP 462
Score = 72.0 bits (175), Expect = 2e-12
Identities = 57/159 (35%), Positives = 66/159 (41%), Gaps = 25/159 (15%)
Query: 35 PPGMGLNQNRGPMGPG--PGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPP--H 90
PP G++ P PG P SG PP P P PP P P H P P H
Sbjct: 310 PPAPGVH----PPAPGVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVH 365
Query: 91 PQPHQQQQPPPPPQDSSKPVV-AQGPG---PAPGVGSAPPASSSAPPATPPTSGA----P 142
P P P P + P V Q PG PAPG+ P PP P++ P
Sbjct: 366 PPPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHPSAPGVHPQP 425
Query: 143 PG---SGPG---PTPTPP---PAVTSAPPGAPPPTPPSS 172
PG S PG PTP PP P + S PG PP PP++
Sbjct: 426 PGVHPSNPGVHPPTPMPPMLRPPLPSEGPGNIPPPPPTN 464
Score = 45.1 bits (105), Expect = 2e-04
Identities = 34/107 (31%), Positives = 43/107 (40%), Gaps = 19/107 (17%)
Query: 34 PPPGMGLNQNRGPMGPGPGQSGPK-----PPIPPPPPHQQQQQPPPQ-QPP---PQQPPP 84
PPP G++ P PG + P P + PP P Q P QPP P P
Sbjct: 366 PPPSAGVH----PQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHPSAPGV 421
Query: 85 HQPPP--HPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASS 129
H PP HP P P P P+ ++GPG P PP ++
Sbjct: 422 HPQPPGVHPSNPGVHPPTPMPPMLRPPLPSEGPGNIP----PPPPTN 464
>gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2
[Homo sapiens]
Length = 1132
Score = 104 bits (259), Expect = 3e-22
Identities = 96/292 (32%), Positives = 111/292 (38%), Gaps = 59/292 (20%)
Query: 35 PPGMGLNQNRG---PMGPGPGQSGPKPPIPPPPP----------HQQQQQPPPQQPPPQQ 81
PP +G Q P+G P GP P PPPPP H PP PPP
Sbjct: 674 PPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPIT 733
Query: 82 PPPHQPPPHPQPHQ--QQQPPPPPQDSSK--------PVVAQGP-GPAPGVGSAPPASSS 130
PP PPPH P +D++K P V G G A S S+
Sbjct: 734 PPVSIPPPHTPPISIPNSTIAGINEDTTKDLSIGNPIPTVVSGARGNAESGDSVKMYGSA 793
Query: 131 APPATPPTSGAPP-----------GSGPGPT---PTPPPAVTSAPPGAPP-------PTP 169
PPA P PP G PGP P + A PG P P P
Sbjct: 794 VPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPP 853
Query: 170 PSSGVPTTPPQAGGPPPPPAAV---PGPGPGPKQGPGPGGPKGGKMPGGP--KPGGGPGL 224
P PP+ P PP + P PGPG P P G KG P GP +PGG PGL
Sbjct: 854 HLQRFPLMPPR----PMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGL 909
Query: 225 STPGGHPKPPHRGGGEPRGGRQHHPPYHQQHHQGPPPGGPGGRSEEKISDSE 276
PG P GG E R GRQ P QQ Q P P + +++ S+
Sbjct: 910 GGPG-----PGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQ 956
Score = 77.4 bits (189), Expect = 4e-14
Identities = 83/253 (32%), Positives = 94/253 (37%), Gaps = 57/253 (22%)
Query: 56 PKP-PIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQG 114
PKP P+P PP P P PP Q PPHQP P P Q P P P+
Sbjct: 644 PKPLPVPVPPI----PVPAPITVPPPQVPPHQPGP-PVVGALQPPAFTP-----PLGIPP 693
Query: 115 PGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGV 174
PG PGV PP P P P PGP P P V+ PP PP + P+S +
Sbjct: 694 PGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPNSTI 753
Query: 175 -----PTTPPQAGGPPPP-----------------------PAAVPGPGPGP-------- 198
TT + G P P P A P P P
Sbjct: 754 AGINEDTTKDLSIGNPIPTVVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSL 813
Query: 199 --KQGPGPGGPKGGKMPGGPKPGGGPG---LSTPGGHPKPPHRGGGEPRGGRQHHPPYHQ 253
QG PG G + P G PG L P G P PPH P + PP+
Sbjct: 814 LGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMP-PPHL-QRFPLMPPRPMPPH-- 869
Query: 254 QHHQGPPPGGPGG 266
H+GPPP GPGG
Sbjct: 870 MMHRGPPP-GPGG 881
Score = 60.1 bits (144), Expect = 7e-09
Identities = 38/118 (32%), Positives = 46/118 (38%), Gaps = 6/118 (5%)
Query: 83 PPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATP-----P 137
P +PP P PH Q+ P PP+ ++ +GP P PG + PP P P
Sbjct: 843 PLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVR 902
Query: 138 TSGAPPGSGPGPTP-TPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGP 194
G P GPGP P P P P P P P Q PPP+ P P
Sbjct: 903 PGGMPGLGGPGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPP 960
Score = 59.3 bits (142), Expect = 1e-08
Identities = 44/99 (44%), Positives = 46/99 (46%), Gaps = 14/99 (14%)
Query: 19 RGGGGGRGGLHDFRSPPP-GM-GLNQNRGPM---GPGPGQSGPKPPIPPPPPHQQQQQPP 73
RG G GG F PPP GM G GP G PG GP P P +QQPP
Sbjct: 873 RGPPPGPGG---FAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQQPP 929
Query: 74 PQQPPPQQPPPHQPPPHPQPHQQQQPPP---PPQDSSKP 109
Q PQQ P Q P PQ QQQQPPP PP +P
Sbjct: 930 QQ---PQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQP 965
Score = 52.4 bits (124), Expect = 1e-06
Identities = 44/112 (39%), Positives = 47/112 (41%), Gaps = 16/112 (14%)
Query: 135 TPPTSGAPPGSGPGPTPTPP---PA-VTSAPPGAPP--PTPPSSGV---PTTPPQAGGPP 185
T P S P P P P PP PA +T PP PP P PP G P P G PP
Sbjct: 637 TEPVSPIPK---PLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLGIPP 693
Query: 186 P--PPAAVPGPGPGPKQGPG--PGGPKGGKMPGGPKPGGGPGLSTPGGHPKP 233
P P P P P P PG P G +P GP P P +S P H P
Sbjct: 694 PGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPP 745
Score = 52.0 bits (123), Expect = 2e-06
Identities = 35/87 (40%), Positives = 40/87 (45%), Gaps = 12/87 (13%)
Query: 14 GGFHRRGGGGGRGGLHDFRSPPPGMGLNQNRG--PMGPGPGQSGPKPPIPPPPPHQQQQQ 71
G F R GG G GG P PG G ++R P Q P+P P P QQQQQ
Sbjct: 898 GPFVRPGGMPGLGG------PGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQ 951
Query: 72 PPPQQPPPQQPPPHQPPPHPQPHQQQQ 98
PPP QQPPP Q P + +Q
Sbjct: 952 PPPS----QQPPPTQQQPQQFRNDNRQ 974
Score = 50.4 bits (119), Expect = 6e-06
Identities = 62/258 (24%), Positives = 79/258 (30%), Gaps = 62/258 (24%)
Query: 62 PPPPHQQQQQPPPQQPPPQQPPPHQPPPHP------------------QPHQQQQPPPPP 103
PPPP + +PP Q P P Q P Q Q Q PP P
Sbjct: 140 PPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQLQQILQTFQQPPKP 199
Query: 104 QDSS--KPVVAQGPGPAPGVGSAPPASSSAPPATPPTS----------------GAPPGS 145
Q + V+AQ + + P S A PP P
Sbjct: 200 QSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPEAV 259
Query: 146 GPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQ----- 200
T+AP A PP P ++ P A PPPP A PG G +Q
Sbjct: 260 EESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQ 319
Query: 201 -------GPGPGGPKGGKM-------PGGPKPGGG-------PGLSTPGGHPKPPHRGGG 239
P G + M P G PG G P ++ P P PP +
Sbjct: 320 HQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQPF 379
Query: 240 EPRGGRQHHPPYHQQHHQ 257
+ Q+ P + H Q
Sbjct: 380 QASFQAQNEPLTQKPHQQ 397
Score = 43.1 bits (100), Expect = 9e-04
Identities = 47/141 (33%), Positives = 50/141 (35%), Gaps = 20/141 (14%)
Query: 126 PASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPP 185
P + A TS P S P P P P P P P P P + P PP GPP
Sbjct: 622 PENEVAQNGGAETSHTEPVS-PIPKPLPVPV-----PPIPVPAPITVPPPQVPPHQPGPP 675
Query: 186 PPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPK--PPHRGGGEPRG 243
A P P P G P G PG P P P PG +P PP G P G
Sbjct: 676 VVGALQP-----PAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPP---GFLPPG 727
Query: 244 GRQHHPPYHQQHHQGPPPGGP 264
PP PPP P
Sbjct: 728 ----PPPPITPPVSIPPPHTP 744
Score = 43.1 bits (100), Expect = 9e-04
Identities = 40/142 (28%), Positives = 44/142 (30%), Gaps = 44/142 (30%)
Query: 23 GGRGGLHDFRSPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQP 82
G R GL + PP M P Q P P P PPH + PPP P
Sbjct: 836 GARPGLIPLQRPPG----------MPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMP 885
Query: 83 PPHQP----PPH----------------------------PQPHQQQQPPPPPQDSSKPV 110
PPH PPH QP QQ Q P PQ +P
Sbjct: 886 PPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQ 945
Query: 111 VAQGPGPAPGVGSAPPASSSAP 132
Q P P PP + P
Sbjct: 946 QQQQQQPPP--SQQPPPTQQQP 965
Score = 33.1 bits (74), Expect = 0.91
Identities = 30/112 (26%), Positives = 34/112 (30%), Gaps = 24/112 (21%)
Query: 54 SGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPP----------PHPQPHQQQQPPPP- 102
+ P +PP P P P PPP Q P P HQ P
Sbjct: 273 TAPAAAVPPAPT---ATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPR 329
Query: 103 -------PQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGP 147
P P+ G P G+ PP A P PPT PP P
Sbjct: 330 MMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPT---PPVQQP 378
Score = 32.0 bits (71), Expect = 2.0
Identities = 23/77 (29%), Positives = 29/77 (37%), Gaps = 8/77 (10%)
Query: 35 PPGMGLNQN----RGPMGPGPGQSG----PKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQ 86
P MG+ Q+ + P+ P G P PP PP PP QQP
Sbjct: 328 PRMMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQPFQASFQAQN 387
Query: 87 PPPHPQPHQQQQPPPPP 103
P +PHQQ+ P
Sbjct: 388 EPLTQKPHQQEMEVEQP 404
Score = 31.6 bits (70), Expect = 2.6
Identities = 27/75 (36%), Positives = 31/75 (41%), Gaps = 14/75 (18%)
Query: 29 HDFRSPP----PGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPP 84
H PP PG GL P P P + +P IPP PP QQ P Q Q P
Sbjct: 340 HQVPLPPNGQMPGFGLL----PTPPFPPMA--QPVIPPTPPVQQ----PFQASFQAQNEP 389
Query: 85 HQPPPHPQPHQQQQP 99
PH Q + +QP
Sbjct: 390 LTQKPHQQEMEVEQP 404
Score = 31.2 bits (69), Expect = 3.5
Identities = 36/161 (22%), Positives = 62/161 (38%), Gaps = 28/161 (17%)
Query: 460 PEKLAQKNPMYQKERETPPRFAQHGT------FEYEYSQRWKSLDEMEKQQREQVEKNMK 513
P+ A + P Q++++ PP T F + Q++ S + E+ R ++
Sbjct: 936 PQPQAPQQPQQQQQQQPPPSQQPPPTQQQPQQFRNDNRQQFNSGRDQERFGRRSFGNRVE 995
Query: 514 DAKDKLESEMEDAYHEHQANLLRQDLMRRQEELRRMEELHNQEMQKRKEMQLRQEEERRR 573
+ +++ + +D +N R++ RR + R +L EER R
Sbjct: 996 NDRERYGNRNDD---RDNSNRDRREWGRRSPDRDRHRDL----------------EERNR 1036
Query: 574 REEEMMIRQREMEEQMRRQREESYSRMGYMDPRERDMRMGG 614
R R RE + + R R E G P D R GG
Sbjct: 1037 RSSGH--RDRERDSRDRESRREKEEARGKEKPEVTD-RAGG 1074
Score = 30.0 bits (66), Expect = 7.7
Identities = 30/108 (27%), Positives = 38/108 (35%), Gaps = 27/108 (25%)
Query: 599 RMGYMDPRERDMRMGGGGAMNMGDPYGSGGQKFPPLGGGGGIGYEANPGVPPATMSGSMM 658
R M PR M M+ G P G GG PP G G P V P M G
Sbjct: 857 RFPLMPPRPMPPHM-----MHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPG--- 908
Query: 659 GSDMRTERFGQGGAGPVGGQGPRGMGPGTPAGYGRGREEYEGPNKKPR 706
+GG GP GPG P ++ + P ++P+
Sbjct: 909 ----------------LGGPGP---GPGGPEDRDGRQQPPQQPQQQPQ 937
>gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1
[Homo sapiens]
Length = 1147
Score = 104 bits (259), Expect = 3e-22
Identities = 96/292 (32%), Positives = 111/292 (38%), Gaps = 59/292 (20%)
Query: 35 PPGMGLNQNRG---PMGPGPGQSGPKPPIPPPPP----------HQQQQQPPPQQPPPQQ 81
PP +G Q P+G P GP P PPPPP H PP PPP
Sbjct: 689 PPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPIT 748
Query: 82 PPPHQPPPHPQPHQ--QQQPPPPPQDSSK--------PVVAQGP-GPAPGVGSAPPASSS 130
PP PPPH P +D++K P V G G A S S+
Sbjct: 749 PPVSIPPPHTPPISIPNSTIAGINEDTTKDLSIGNPIPTVVSGARGNAESGDSVKMYGSA 808
Query: 131 APPATPPTSGAPP-----------GSGPGPT---PTPPPAVTSAPPGAPP-------PTP 169
PPA P PP G PGP P + A PG P P P
Sbjct: 809 VPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPP 868
Query: 170 PSSGVPTTPPQAGGPPPPPAAV---PGPGPGPKQGPGPGGPKGGKMPGGP--KPGGGPGL 224
P PP+ P PP + P PGPG P P G KG P GP +PGG PGL
Sbjct: 869 HLQRFPLMPPR----PMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGL 924
Query: 225 STPGGHPKPPHRGGGEPRGGRQHHPPYHQQHHQGPPPGGPGGRSEEKISDSE 276
PG P GG E R GRQ P QQ Q P P + +++ S+
Sbjct: 925 GGPG-----PGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQ 971
Score = 77.4 bits (189), Expect = 4e-14
Identities = 83/253 (32%), Positives = 94/253 (37%), Gaps = 57/253 (22%)
Query: 56 PKP-PIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQG 114
PKP P+P PP P P PP Q PPHQP P P Q P P P+
Sbjct: 659 PKPLPVPVPPI----PVPAPITVPPPQVPPHQPGP-PVVGALQPPAFTP-----PLGIPP 708
Query: 115 PGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGV 174
PG PGV PP P P P PGP P P V+ PP PP + P+S +
Sbjct: 709 PGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPNSTI 768
Query: 175 -----PTTPPQAGGPPPP-----------------------PAAVPGPGPGP-------- 198
TT + G P P P A P P P
Sbjct: 769 AGINEDTTKDLSIGNPIPTVVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSL 828
Query: 199 --KQGPGPGGPKGGKMPGGPKPGGGPG---LSTPGGHPKPPHRGGGEPRGGRQHHPPYHQ 253
QG PG G + P G PG L P G P PPH P + PP+
Sbjct: 829 LGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMP-PPHL-QRFPLMPPRPMPPH-- 884
Query: 254 QHHQGPPPGGPGG 266
H+GPPP GPGG
Sbjct: 885 MMHRGPPP-GPGG 896
Score = 60.1 bits (144), Expect = 7e-09
Identities = 38/118 (32%), Positives = 46/118 (38%), Gaps = 6/118 (5%)
Query: 83 PPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATP-----P 137
P +PP P PH Q+ P PP+ ++ +GP P PG + PP P P
Sbjct: 858 PLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVR 917
Query: 138 TSGAPPGSGPGPTP-TPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGP 194
G P GPGP P P P P P P P Q PPP+ P P
Sbjct: 918 PGGMPGLGGPGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPP 975
Score = 59.3 bits (142), Expect = 1e-08
Identities = 44/99 (44%), Positives = 46/99 (46%), Gaps = 14/99 (14%)
Query: 19 RGGGGGRGGLHDFRSPPP-GM-GLNQNRGPM---GPGPGQSGPKPPIPPPPPHQQQQQPP 73
RG G GG F PPP GM G GP G PG GP P P +QQPP
Sbjct: 888 RGPPPGPGG---FAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQQPP 944
Query: 74 PQQPPPQQPPPHQPPPHPQPHQQQQPPP---PPQDSSKP 109
Q PQQ P Q P PQ QQQQPPP PP +P
Sbjct: 945 QQ---PQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQP 980
Score = 52.4 bits (124), Expect = 1e-06
Identities = 44/112 (39%), Positives = 47/112 (41%), Gaps = 16/112 (14%)
Query: 135 TPPTSGAPPGSGPGPTPTPP---PA-VTSAPPGAPP--PTPPSSGV---PTTPPQAGGPP 185
T P S P P P P PP PA +T PP PP P PP G P P G PP
Sbjct: 652 TEPVSPIPK---PLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLGIPP 708
Query: 186 P--PPAAVPGPGPGPKQGPG--PGGPKGGKMPGGPKPGGGPGLSTPGGHPKP 233
P P P P P P PG P G +P GP P P +S P H P
Sbjct: 709 PGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPP 760
Score = 52.0 bits (123), Expect = 2e-06
Identities = 35/87 (40%), Positives = 40/87 (45%), Gaps = 12/87 (13%)
Query: 14 GGFHRRGGGGGRGGLHDFRSPPPGMGLNQNRG--PMGPGPGQSGPKPPIPPPPPHQQQQQ 71
G F R GG G GG P PG G ++R P Q P+P P P QQQQQ
Sbjct: 913 GPFVRPGGMPGLGG------PGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQ 966
Query: 72 PPPQQPPPQQPPPHQPPPHPQPHQQQQ 98
PPP QQPPP Q P + +Q
Sbjct: 967 PPPS----QQPPPTQQQPQQFRNDNRQ 989
Score = 50.4 bits (119), Expect = 6e-06
Identities = 62/258 (24%), Positives = 79/258 (30%), Gaps = 62/258 (24%)
Query: 62 PPPPHQQQQQPPPQQPPPQQPPPHQPPPHP------------------QPHQQQQPPPPP 103
PPPP + +PP Q P P Q P Q Q Q PP P
Sbjct: 155 PPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQLQQILQTFQQPPKP 214
Query: 104 QDSS--KPVVAQGPGPAPGVGSAPPASSSAPPATPPTS----------------GAPPGS 145
Q + V+AQ + + P S A PP P
Sbjct: 215 QSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPEAV 274
Query: 146 GPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQ----- 200
T+AP A PP P ++ P A PPPP A PG G +Q
Sbjct: 275 EESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQ 334
Query: 201 -------GPGPGGPKGGKM-------PGGPKPGGG-------PGLSTPGGHPKPPHRGGG 239
P G + M P G PG G P ++ P P PP +
Sbjct: 335 HQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQPF 394
Query: 240 EPRGGRQHHPPYHQQHHQ 257
+ Q+ P + H Q
Sbjct: 395 QASFQAQNEPLTQKPHQQ 412
Score = 43.1 bits (100), Expect = 9e-04
Identities = 47/141 (33%), Positives = 50/141 (35%), Gaps = 20/141 (14%)
Query: 126 PASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPP 185
P + A TS P S P P P P P P P P P + P PP GPP
Sbjct: 637 PENEVAQNGGAETSHTEPVS-PIPKPLPVPV-----PPIPVPAPITVPPPQVPPHQPGPP 690
Query: 186 PPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPK--PPHRGGGEPRG 243
A P P P G P G PG P P P PG +P PP G P G
Sbjct: 691 VVGALQP-----PAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPP---GFLPPG 742
Query: 244 GRQHHPPYHQQHHQGPPPGGP 264
PP PPP P
Sbjct: 743 ----PPPPITPPVSIPPPHTP 759
Score = 43.1 bits (100), Expect = 9e-04
Identities = 40/142 (28%), Positives = 44/142 (30%), Gaps = 44/142 (30%)
Query: 23 GGRGGLHDFRSPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQP 82
G R GL + PP M P Q P P P PPH + PPP P
Sbjct: 851 GARPGLIPLQRPPG----------MPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMP 900
Query: 83 PPHQP----PPH----------------------------PQPHQQQQPPPPPQDSSKPV 110
PPH PPH QP QQ Q P PQ +P
Sbjct: 901 PPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQ 960
Query: 111 VAQGPGPAPGVGSAPPASSSAP 132
Q P P PP + P
Sbjct: 961 QQQQQQPPP--SQQPPPTQQQP 980
Score = 33.1 bits (74), Expect = 0.91
Identities = 30/112 (26%), Positives = 34/112 (30%), Gaps = 24/112 (21%)
Query: 54 SGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPP----------PHPQPHQQQQPPPP- 102
+ P +PP P P P PPP Q P P HQ P
Sbjct: 288 TAPAAAVPPAPT---ATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPR 344
Query: 103 -------PQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGP 147
P P+ G P G+ PP A P PPT PP P
Sbjct: 345 MMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPT---PPVQQP 393
Score = 32.0 bits (71), Expect = 2.0
Identities = 23/77 (29%), Positives = 29/77 (37%), Gaps = 8/77 (10%)
Query: 35 PPGMGLNQN----RGPMGPGPGQSG----PKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQ 86
P MG+ Q+ + P+ P G P PP PP PP QQP
Sbjct: 343 PRMMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQPFQASFQAQN 402
Query: 87 PPPHPQPHQQQQPPPPP 103
P +PHQQ+ P
Sbjct: 403 EPLTQKPHQQEMEVEQP 419
Score = 31.6 bits (70), Expect = 2.6
Identities = 27/75 (36%), Positives = 31/75 (41%), Gaps = 14/75 (18%)
Query: 29 HDFRSPP----PGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPP 84
H PP PG GL P P P + +P IPP PP QQ P Q Q P
Sbjct: 355 HQVPLPPNGQMPGFGLL----PTPPFPPMA--QPVIPPTPPVQQ----PFQASFQAQNEP 404
Query: 85 HQPPPHPQPHQQQQP 99
PH Q + +QP
Sbjct: 405 LTQKPHQQEMEVEQP 419
Score = 31.2 bits (69), Expect = 3.5
Identities = 36/161 (22%), Positives = 62/161 (38%), Gaps = 28/161 (17%)
Query: 460 PEKLAQKNPMYQKERETPPRFAQHGT------FEYEYSQRWKSLDEMEKQQREQVEKNMK 513
P+ A + P Q++++ PP T F + Q++ S + E+ R ++
Sbjct: 951 PQPQAPQQPQQQQQQQPPPSQQPPPTQQQPQQFRNDNRQQFNSGRDQERFGRRSFGNRVE 1010
Query: 514 DAKDKLESEMEDAYHEHQANLLRQDLMRRQEELRRMEELHNQEMQKRKEMQLRQEEERRR 573
+ +++ + +D +N R++ RR + R +L EER R
Sbjct: 1011 NDRERYGNRNDD---RDNSNRDRREWGRRSPDRDRHRDL----------------EERNR 1051
Query: 574 REEEMMIRQREMEEQMRRQREESYSRMGYMDPRERDMRMGG 614
R R RE + + R R E G P D R GG
Sbjct: 1052 RSSGH--RDRERDSRDRESRREKEEARGKEKPEVTD-RAGG 1089
Score = 30.0 bits (66), Expect = 7.7
Identities = 30/108 (27%), Positives = 38/108 (35%), Gaps = 27/108 (25%)
Query: 599 RMGYMDPRERDMRMGGGGAMNMGDPYGSGGQKFPPLGGGGGIGYEANPGVPPATMSGSMM 658
R M PR M M+ G P G GG PP G G P V P M G
Sbjct: 872 RFPLMPPRPMPPHM-----MHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPG--- 923
Query: 659 GSDMRTERFGQGGAGPVGGQGPRGMGPGTPAGYGRGREEYEGPNKKPR 706
+GG GP GPG P ++ + P ++P+
Sbjct: 924 ----------------LGGPGP---GPGGPEDRDGRQQPPQQPQQQPQ 952
>gi|18959210 WIRE protein [Homo sapiens]
Length = 440
Score = 103 bits (258), Expect = 4e-22
Identities = 68/198 (34%), Positives = 80/198 (40%), Gaps = 36/198 (18%)
Query: 34 PPPGMGLNQNRGPM------GPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQP 87
PPPG N P+ P + P PP P H ++ PP PPP +PPP
Sbjct: 180 PPPGRRANAPPTPLPMHSSKAPAYNREKPLPPTPGQRLHPGREGPPA--PPPVKPPPSPV 237
Query: 88 PPHPQPHQQQQPPPPPQDSSKPVVAQGPG---------------------PAPGVGSAPP 126
P Q PPPP P V GP P P G APP
Sbjct: 238 NIRTGPSGQSLAPPPPPYRQPPGVPNGPSSPTNESAPELPQRHNSLHRKTPGPVRGLAPP 297
Query: 127 ASSSAPPAT-----PPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQA 181
+SA P+ PP + PP G P P PPP + + APPP PP + PP
Sbjct: 298 PPTSASPSLLSNRPPPPARDPPSRGAAPPP-PPPVIRNGARDAPPPPPPYRMHGSEPPSR 356
Query: 182 GGPPPPPAAVP-GPGPGP 198
G PPPPP+ P GP P P
Sbjct: 357 GKPPPPPSRTPAGPPPPP 374
Score = 75.5 bits (184), Expect = 2e-13
Identities = 83/308 (26%), Positives = 104/308 (33%), Gaps = 61/308 (19%)
Query: 11 GGGGGFHRRGGGGGRGGLHDFRSPPPGMGLNQNRGPMG---PGPGQSGPKPPIPPPPPHQ 67
G GG + GG +GG+ R G G P + P+PP+
Sbjct: 75 GSGGAALQPKGGLFQGGVLKLRPVGAKDGSENLAGKPALQIPSSRAAAPRPPVSAASGRP 134
Query: 68 QQQQPPPQQPPPQQPPPHQP--PPHPQP---------HQQQQPPPPP--QDSSKPVVAQG 114
Q + P+ P +P P +P H PPPPP + ++ P
Sbjct: 135 QDDTDSSRASLPELPRMQRPSLPDLSRPNTTSSTGMKHSSSAPPPPPPGRRANAP----- 189
Query: 115 PGPAPGVGSAPPASSSAPPATPPTSG-----------APPGSGPGPTPT----------- 152
P P P S PA + P PPT G APP P P+P
Sbjct: 190 PTPLPMHSSKAPAYNREKPL-PPTPGQRLHPGREGPPAPPPVKPPPSPVNIRTGPSGQSL 248
Query: 153 -PPPAVTSAPPGAP--PPTPPSSGVPTTP------------PQAG-GPPPPPAAVPGPGP 196
PPP PPG P P +P + P P P G PPPP +A P
Sbjct: 249 APPPPPYRQPPGVPNGPSSPTNESAPELPQRHNSLHRKTPGPVRGLAPPPPTSASPSLLS 308
Query: 197 GPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHPPYHQQHH 256
P P G P P P G + P PP+R G R PP +
Sbjct: 309 NRPPPPARDPPSRGAAPPPPPPVIRNG-ARDAPPPPPPYRMHGSEPPSRGKPPPPPSRTP 367
Query: 257 QGPPPGGP 264
GPPP P
Sbjct: 368 AGPPPPPP 375
Score = 44.7 bits (104), Expect = 3e-04
Identities = 69/282 (24%), Positives = 84/282 (29%), Gaps = 89/282 (31%)
Query: 59 PIPPPPPHQQQQQPPPQQPPPQQPPPHQP-PPHPQPHQQQQ-----------------PP 100
PIPPPPP PPP PPP P HQ P+ + +Q
Sbjct: 2 PIPPPPP------PPPGPPPP--PTFHQANTEQPKLSRDEQRGRGALLQDICKGTKLKKV 53
Query: 101 PPPQDSSKPVVAQGPGPAPGVGSAPPASS----------------SAPPATPPTSGAPPG 144
D S P++ + G + G GS A A + +G P
Sbjct: 54 TNINDRSAPILEKPKGSSGGYGSGGAALQPKGGLFQGGVLKLRPVGAKDGSENLAGKPAL 113
Query: 145 SGPGPTPTPPPAVTSAPPGAPP------------------PTPPSSGVPTTPPQAG---- 182
P P SA G P P+ P P T G
Sbjct: 114 QIPSSRAAAPRPPVSAASGRPQDDTDSSRASLPELPRMQRPSLPDLSRPNTTSSTGMKHS 173
Query: 183 ---GPPPPPAAVPGPGPGP------------KQGPGPGGPKGGKMPGGPKPGGGPGLSTP 227
PPPPP P P ++ P P P PG P P + P
Sbjct: 174 SSAPPPPPPGRRANAPPTPLPMHSSKAPAYNREKPLPPTPGQRLHPGREGPPAPPPVKPP 233
Query: 228 GGHPKPPH-RGGGEPRGGRQHHPPYHQQHHQGPPPGGPGGRS 268
P P + R G + PPY Q PPG P G S
Sbjct: 234 ---PSPVNIRTGPSGQSLAPPPPPYRQ------PPGVPNGPS 266
Score = 43.1 bits (100), Expect = 9e-04
Identities = 25/73 (34%), Positives = 34/73 (46%), Gaps = 11/73 (15%)
Query: 34 PPPGMGLNQNRGPMGPGPG---QSGPKPPIPPPPPHQQQQQPPPQQ----PPPQQ----P 82
PPP +RG P P ++G + PPPPP++ PP + PPP + P
Sbjct: 311 PPPPARDPPSRGAAPPPPPPVIRNGARDAPPPPPPYRMHGSEPPSRGKPPPPPSRTPAGP 370
Query: 83 PPHQPPPHPQPHQ 95
PP PPP H+
Sbjct: 371 PPPPPPPLRNGHR 383
>gi|119829187 alpha 1 type XVII collagen [Homo sapiens]
Length = 1497
Score = 100 bits (250), Expect = 4e-21
Identities = 100/304 (32%), Positives = 121/304 (39%), Gaps = 56/304 (18%)
Query: 21 GGGGRGGLHDFRSPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQ----Q 76
G G G + PP +GL RG +G PG G K P+ PP P Q + P+ +
Sbjct: 665 GPKGSSGSPGPQGPPGPVGLQGLRGEVGL-PGVKGDKGPMGPPGPKGDQGEKGPRGLTGE 723
Query: 77 PPPQQPP-------------PHQPPPHPQPHQQQQ---------PPPPPQDSSKPVVA-- 112
P + P P P H P +Q PP P D KP +
Sbjct: 724 PGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGP 783
Query: 113 QGPGPAPGVGSAP--PASSSAPPATPPTSGAPPGSGPGPTPTPPPAV-TSAPPGAPPPTP 169
QGP PG P AP + G+ + PGP P PP A+ PPGAP P
Sbjct: 784 QGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGP-PGPPGAMGPPGPPGAPGPAG 842
Query: 170 PSSGVPTTPPQAG--GPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGG------ 221
P+ G+P GPP PP PGP PGP GP G +PG P P G
Sbjct: 843 PA-GLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPGEGLPGPPGPPGSFLSNSE 901
Query: 222 PGLSTPGGHPKPPHRGGGE----PRG--GRQHHPPYHQQ-------HHQGPP-PGGPGGR 267
LS P G P PP G + PRG G Q P + + QGPP P GP G
Sbjct: 902 TFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGP 961
Query: 268 SEEK 271
+K
Sbjct: 962 KGDK 965
Score = 82.8 bits (203), Expect = 1e-15
Identities = 114/412 (27%), Positives = 140/412 (33%), Gaps = 89/412 (21%)
Query: 12 GGGGFHRRGGGGGRGGLHDFRSPP-----PGM-GLNQNRGPMG-PG-PGQSGPKP----- 58
G G G G G+ R PP PG GL +GP G PG PG+ G K
Sbjct: 746 GPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAP 805
Query: 59 --------------PIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQ 104
P PP PP PP P P P P H + Q PP PP
Sbjct: 806 GKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGL--PGHQEVLNLQGPPGPP- 862
Query: 105 DSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAP-PGSGPGPTPTPPPAVTSAPPG 163
GP PG P P PP G P P PG + S PPG
Sbjct: 863 ---------GPRGPPG----PSIPGPPGPRGPPGEGLPGPPGPPGSFLSNSETFLSGPPG 909
Query: 164 APPPTPPSS--GVPTTPPQAGGPPPPPAAVPGPGP------GPKQGPGPGGPKGGK---- 211
P P P G P G P + G GP PGP GPKG K
Sbjct: 910 PPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPG 969
Query: 212 ------MPGGPKPGGGPG---LSTPGGHPKPPHRGGGEPRGG---RQHHPPYHQQHH--- 256
+P GP GG +S P G P PP G G +Q+ Y Q
Sbjct: 970 VPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRS 1029
Query: 257 -----QGPP-PGGPGGR----SEEKISDSEGFKANLSLLRRPGEKTYTQRCRLFVGNLPA 306
QGPP P GP G + E SE +S LR G + ++ A
Sbjct: 1030 YLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILA 1089
Query: 307 DITEDEFKRLFAKY--------GEPGEVFINKGKGFGFIKLESRALAEIAKA 350
+ D+ ++ +Y G PG + +L SR L+ ++ +
Sbjct: 1090 VLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSS 1141
Score = 57.4 bits (137), Expect = 5e-08
Identities = 90/305 (29%), Positives = 101/305 (33%), Gaps = 87/305 (28%)
Query: 49 PGP----GQSGPK--------PPIPPPPPHQQQQQPPPQQ-----PPPQQPPPHQPPPHP 91
PGP G GPK P IP P H Q P Q+ P + P + P
Sbjct: 569 PGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRGREGP 628
Query: 92 QPHQQQQPPPPPQDSSKPVVAQGPGP--APGV-GSAPPASSSAPPAT--PP--------- 137
+ + PP + + A PGP PGV GS P SS P PP
Sbjct: 629 MGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPVGLQGLR 688
Query: 138 ----TSGAPPGSGPGPTPTP--------PPAVTSAP-----------PGAP----PPTPP 170
G GP P P P +T P PGA P P
Sbjct: 689 GEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPD 748
Query: 171 SSGVP------TTPPQAGGPPPP--------------PAAVPG-PG-PGPKQGPGPGG-- 206
P T P GPP P P +PG PG PG K PG G
Sbjct: 749 GHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKI 808
Query: 207 --PKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHPPYHQQHHQGPP-PGG 263
+G M P P G PG P G P P G P G H + Q GPP P G
Sbjct: 809 VTSEGSSMLTVPGPPGPPGAMGPPGPPGAP--GPAGPAGLPGHQEVLNLQGPPGPPGPRG 866
Query: 264 PGGRS 268
P G S
Sbjct: 867 PPGPS 871
Score = 47.0 bits (110), Expect = 6e-05
Identities = 54/188 (28%), Positives = 62/188 (32%), Gaps = 28/188 (14%)
Query: 115 PGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGV 174
PGP +GS P P TP G P PGP + PG P
Sbjct: 569 PGPKGDMGSPGPKGDRGFPGTPGIPG--PLGHPGPQGPKGQKGSVGDPGMEGPMGQRGRE 626
Query: 175 -PTTPPQAGGPPPPP-----AAVPGPGP-GPKQGPGPGGPKGGKMPGGPKPGGGPG---- 223
P P GPP A PGP GP PG GPKG G P P G PG
Sbjct: 627 GPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSS--GSPGPQGPPGPVGL 684
Query: 224 LSTPGGHPKPPHRGGGEPRGGRQHHPPYHQQHHQGPPPGGPGGRSEEKISDSEGFKANLS 283
G P +G P G PP P G G + ++ G +
Sbjct: 685 QGLRGEVGLPGVKGDKGPMG-----PP--------GPKGDQGEKGPRGLTGEPGMRGLPG 731
Query: 284 LLRRPGEK 291
+ PG K
Sbjct: 732 AVGEPGAK 739
Score = 42.7 bits (99), Expect = 0.001
Identities = 40/115 (34%), Positives = 42/115 (36%), Gaps = 17/115 (14%)
Query: 173 GVPTTPPQAGGPPPP-PAAVPG-PG-PGPKQGPGPGGPKGGK-------MPGGPKPGGGP 222
G P G P P PG PG PGP PGP GPKG K M G G
Sbjct: 567 GSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRGRE 626
Query: 223 GLSTPGGHPKPPHRGGGEPRGGRQHHPPYHQQHHQGPPPGGPGGRSEEKISDSEG 277
G P G PP G RG P+ PPG PG + S S G
Sbjct: 627 GPMGPRGEAGPPGSGEKGERGAAGEPGPH-------GPPGVPGSVGPKGSSGSPG 674
Score = 35.0 bits (79), Expect = 0.24
Identities = 27/75 (36%), Positives = 33/75 (44%), Gaps = 17/75 (22%)
Query: 623 PYGSGGQKFPPLGGGGGIGYEANPGVPPATMSGSMMGSDMRTERFG---QGGAGPVGGQG 679
P G G + PP G G++ G+P + SGS FG QG GP G QG
Sbjct: 913 PPGPKGDQGPP----GPRGHQGEQGLPGFSTSGS--------SSFGLNLQGPPGPPGPQG 960
Query: 680 PRG--MGPGTPAGYG 692
P+G PG P G
Sbjct: 961 PKGDKGDPGVPGALG 975
Score = 33.9 bits (76), Expect = 0.53
Identities = 28/86 (32%), Positives = 31/86 (36%), Gaps = 7/86 (8%)
Query: 138 TSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPG 197
T PPG P P PP ++ T T GPP + PGP
Sbjct: 1396 TVQGPPGQ---PGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGP- 1451
Query: 198 PKQGPGPGGPKGGKMPGGPKPGGGPG 223
K GP GP G PG P P G G
Sbjct: 1452 -KGDRGPAGPPG--HPGPPGPRGHKG 1474
Score = 33.5 bits (75), Expect = 0.70
Identities = 27/84 (32%), Positives = 34/84 (40%), Gaps = 18/84 (21%)
Query: 618 MNMGDPYGSGGQKFPP---------LGGGGGIGYEANPGVPPATMSGSMMGSDMRTERFG 668
+N+ P G G + PP G G G PG P + +S S E F
Sbjct: 853 LNLQGPPGPPGPRGPPGPSIPGPPGPRGPPGEGLPGPPGPPGSFLSNS--------ETFL 904
Query: 669 QGGAGPVGGQGPRG-MGPGTPAGY 691
G GP G GP+G GP P G+
Sbjct: 905 SGPPGPPGPPGPKGDQGPPGPRGH 928
Score = 33.5 bits (75), Expect = 0.70
Identities = 22/58 (37%), Positives = 26/58 (44%), Gaps = 16/58 (27%)
Query: 190 AVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPP----HRGGGEPRG 243
A+ GP PG K G GPKG + P GP GHP PP H+G +G
Sbjct: 1435 AIQGP-PGQKGEMGTPGPKGDRGPAGPP-----------GHPGPPGPRGHKGEKGDKG 1480
Score = 32.7 bits (73), Expect = 1.2
Identities = 34/124 (27%), Positives = 45/124 (36%), Gaps = 23/124 (18%)
Query: 603 MDPRERDMRMGGGGAMNMGDPYGSGGQKFPPLGG-GGGIGYEANPGVPPATMSGSMMGSD 661
M+ ++R G +MG P G + FP G G +G+ G P GS+
Sbjct: 558 MEQENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQG--PKGQKGSVGDPG 615
Query: 662 MRT---ERFGQGGAGPVGGQGPRGMG----------------PGTPAGYG-RGREEYEGP 701
M +R +G GP G GP G G PG P G +G GP
Sbjct: 616 MEGPMGQRGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGP 675
Query: 702 NKKP 705
P
Sbjct: 676 QGPP 679
Score = 30.4 bits (67), Expect = 5.9
Identities = 31/99 (31%), Positives = 36/99 (36%), Gaps = 23/99 (23%)
Query: 613 GGGGAMNMGDPYGSGGQKFPPLGGGGGIGYEANPGVPPATMSGSMMGSDMRTERFGQGGA 672
G G M P G G+K P G G G+P A G+ G A
Sbjct: 698 GDKGPMGPPGPKGDQGEKGPR----GLTGEPGMRGLPGAVGEPGAKGA--------MGPA 745
Query: 673 GPVGGQGPRG----------MGPGTPAGYGRGREEYEGP 701
GP G QGPRG GP P+G G+ GP
Sbjct: 746 GPDGHQGPRGEQGLTGMPGIRGPPGPSG-DPGKPGLTGP 783
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 100 bits (248), Expect = 6e-21
Identities = 90/266 (33%), Positives = 100/266 (37%), Gaps = 54/266 (20%)
Query: 46 PMGPGPGQSGPKPPIPPPPPHQQ----QQQPPPQQPPPQ----------QP----PPHQP 87
P P P + + P P PP QQ + QP P +PP Q QP PP QP
Sbjct: 296 PSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQP 355
Query: 88 P----PHPQPHQQQQPPPPPQDSSKPVVAQGPGPA-----PGVGSAPPASSSAPPATPPT 138
P P QP +PP S KP Q PGP PGVG P + PA PPT
Sbjct: 356 PGTTKPPAQPLGPAKPPAQQTGSEKPSSEQ-PGPKALAQPPGVGKTP--AQQPGPAKPPT 412
Query: 139 S--GAP-----------PGSGPGPTPTPP----PAVTSAPPGAPPPTPPSSGVPTTPP-Q 180
G P P PGPT TP P A P T PT PP Q
Sbjct: 413 QQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQ 472
Query: 181 AGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKP---GGGPGLSTP--GGHPKPPH 235
GP PP PGP P Q PG P + PG KP GP +P G KPP
Sbjct: 473 LPGPAKPPPQQPGPAKPPPQQPGSAKPP-SQQPGSTKPPPQQPGPAKPSPQQPGSTKPPS 531
Query: 236 RGGGEPRGGRQHHPPYHQQHHQGPPP 261
+ G + Q P Q P
Sbjct: 532 QQPGSAKPSAQQPSPAKPSAQQSTKP 557
Score = 97.8 bits (242), Expect = 3e-20
Identities = 78/232 (33%), Positives = 91/232 (39%), Gaps = 34/232 (14%)
Query: 56 PKPPIPPPPPHQQQQ--QPPPQQPPPQ--QPPPHQPPPHP---------QPHQQQQPPPP 102
P P P PP QQ +PP QQP + QP P +PP P QP + P P
Sbjct: 296 PSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQP 355
Query: 103 PQDSSKPVVAQGPG--PAPGVGSAPPASSSAPP---ATPPTSGAPPGSGPGPTPTPPPAV 157
P + P GP PA GS P+S P A PP G P PGP P V
Sbjct: 356 PGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQV 415
Query: 158 TSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPK 217
G P P G+ + P +A GP P PGPG P Q GPG +
Sbjct: 416 -----GTPKPLAQQPGLQS-PAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKP 469
Query: 218 PGGGPGLSTPG----GHPKPPHRGGGEPRGGRQHHPPYHQQHHQGPPPGGPG 265
P PG + P G KPP + G + PP Q PPP PG
Sbjct: 470 PSQLPGPAKPPPQQPGPAKPPPQQPGSAK------PPSQQPGSTKPPPQQPG 515
Score = 90.5 bits (223), Expect = 5e-18
Identities = 73/212 (34%), Positives = 81/212 (38%), Gaps = 25/212 (11%)
Query: 42 QNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPP------PQQPPPQQPPPHQ---PPPHPQ 92
Q GP P Q+G + P P + QPP QQP P +PP Q P P Q
Sbjct: 364 QPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQ 423
Query: 93 PHQQQQPPPPPQDSSKPVVAQGPG--PA----PGVGSAPPASSSAPPATPPTSGAPPGSG 146
Q P P + PV GPG PA PG SA + PP+ P PP
Sbjct: 424 QPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQ 483
Query: 147 PGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGG 206
PGP PP SA PP P S P PPQ GP P PG P Q PG
Sbjct: 484 PGPAKPPPQQPGSA---KPPSQQPGSTKP--PPQQPGPAKPSPQQPGSTKPPSQQPGSAK 538
Query: 207 PKGGKMPGGPKPGG----GPGLSTPGGHPKPP 234
P + P KP P T G P P
Sbjct: 539 P-SAQQPSPAKPSAQQSTKPVSQTGSGKPLQP 569
Score = 79.0 bits (193), Expect = 1e-14
Identities = 70/196 (35%), Positives = 81/196 (41%), Gaps = 25/196 (12%)
Query: 35 PPGMGLN--QNRGPMGPGPGQSG-PKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPP--- 88
PPG+G Q GP P Q G PKP P + P P + P QQP P + P
Sbjct: 394 PPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQ 453
Query: 89 --PHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPAS--SSAPPATPPTSGAPPG 144
P QQ P PP S P A+ P PG PP S+ PP+ P S PP
Sbjct: 454 AGPGKTSAQQTGPTKPP--SQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPP 511
Query: 145 SGPGPT-PTP-------PPAVT--SAPPGAPPPTP--PSSGVPTTPPQAGGPPPPPAAVP 192
PGP P+P PP+ SA P A P+P PS+ T P G P P
Sbjct: 512 QQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTG-SGKPLQPP 570
Query: 193 GPGPGPKQGPGPGGPK 208
P KQ P G PK
Sbjct: 571 TVSPSAKQPPSQGLPK 586
Score = 75.1 bits (183), Expect = 2e-13
Identities = 62/156 (39%), Positives = 70/156 (44%), Gaps = 20/156 (12%)
Query: 32 RSPPPGMGLNQNRGPMGPGPGQSGP-KPPI----PPPPPHQQ--QQQPPPQQPPPQQPPP 84
+ P PG Q GP Q+GP KPP P PP QQ +PPPQQP +PP
Sbjct: 442 QQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPS 501
Query: 85 HQPPPHPQPHQQQQP--PPPPQDSSKPVVAQGPGPA-PGVGSAPPASSSAPPATPPTSGA 141
QP P QQ P P P Q S +Q PG A P PA SA +T P S
Sbjct: 502 QQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVS-- 559
Query: 142 PPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTT 177
GSG P PP V+ P A PPS G+P T
Sbjct: 560 QTGSG---KPLQPPTVS---PSA--KQPPSQGLPKT 587
Score = 72.8 bits (177), Expect = 1e-12
Identities = 74/249 (29%), Positives = 89/249 (35%), Gaps = 68/249 (27%)
Query: 57 KPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPG 116
KPP+ PP +Q P + P QQ + QP + + PP + KP+ QGP
Sbjct: 208 KPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPP---GTGKPI--QGPT 262
Query: 117 PAPGVG------------------------SAPPA--SSSAPPATPPTSGAPPGSGPG-- 148
P S P+ S S PP PT G PP PG
Sbjct: 263 QTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHE 322
Query: 149 ---PTPTPPPAVTSA-------PPGA--PPPTPPSSGVPTTPPQAGGPPPPP-------- 188
P P PPA S PG PP PP + P P Q GP PP
Sbjct: 323 KSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKP--PAQPLGPAKPPAQQTGSEK 380
Query: 189 -----------AAVPGPGPGPKQGPGPGGPKGGKMPGGPKP-GGGPGLSTPGGHPKPPHR 236
A PG G P Q PGP P ++ G PKP PGL +P P P
Sbjct: 381 PSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQV-GTPKPLAQQPGLQSPAKAPGPTKT 439
Query: 237 GGGEPRGGR 245
+P G+
Sbjct: 440 PVQQPGPGK 448
Score = 68.6 bits (166), Expect = 2e-11
Identities = 50/128 (39%), Positives = 56/128 (43%), Gaps = 23/128 (17%)
Query: 41 NQNRGPMGPGPGQSGP-KPPIPPP----PPHQQ--QQQPPPQQPPPQQPPPHQP----PP 89
+Q GP P P Q GP KPP P PP QQ +PPPQQP P +P P QP PP
Sbjct: 471 SQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPP 530
Query: 90 HPQP----HQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGS 145
QP QQP P +KP Q P GS P PP P++ PP
Sbjct: 531 SQQPGSAKPSAQQPSP-----AKPSAQQSTKPVSQTGSGKPLQ---PPTVSPSAKQPPSQ 582
Query: 146 GPGPTPTP 153
G T P
Sbjct: 583 GLPKTICP 590
Score = 60.8 bits (146), Expect = 4e-09
Identities = 58/227 (25%), Positives = 74/227 (32%), Gaps = 48/227 (21%)
Query: 53 QSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPP--HQPPPHPQPHQQQQPPPPPQDSSKPV 110
+S P+P P +Q + P P++PPP QP H P + + PP SKP
Sbjct: 674 KSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPA 733
Query: 111 VAQGPGPAPGVGSAPPASS--SAPPATPPTSGAPPGSGPGPTPTPPPAVT-------SAP 161
+ P AP A P PT+ S P P + + P
Sbjct: 734 PPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTP 793
Query: 162 PGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPG--------PGP--------------- 198
P PS P T + P A+P P PGP
Sbjct: 794 PLKTDSAKPSQSFPPTGEKVS--PFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQK 851
Query: 199 ---------KQGPGPGG---PKGGKMPGGPKPGGGPGLSTPGGHPKP 233
K P P PKG P GP+P G + TP PKP
Sbjct: 852 KEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKP 898
Score = 59.3 bits (142), Expect = 1e-08
Identities = 51/165 (30%), Positives = 62/165 (37%), Gaps = 14/165 (8%)
Query: 49 PGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSK 108
P S P P P + QPPP PPP PPP P P PP PP S K
Sbjct: 2377 PSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPP--PPPPPPPPPPPPPPLPPPTSPK 2434
Query: 109 PVVAQGPGPAPGVGSAPPASSSAP----PATPPTSGAPPGSGPGPTPTPPPAVTSAPPGA 164
P + P + A P +++ P T T+ +G P T+ PP
Sbjct: 2435 PTIL----PKKKLTVASPVTTATPLFDAVTTLETTAVLRSNG---LPVTRICTTAPPPVP 2487
Query: 165 PPPTP-PSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPK 208
P P+ PS V T P+ PP P V P Q P PK
Sbjct: 2488 PKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPK 2532
Score = 58.9 bits (141), Expect = 2e-08
Identities = 47/139 (33%), Positives = 56/139 (40%), Gaps = 14/139 (10%)
Query: 53 QSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVA 112
Q P PP PPPPP PPP PPP PPP P P P ++ P ++ A
Sbjct: 2404 QPPPPPPPPPPPP-----PPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDA 2458
Query: 113 QGPGPAPGV--GSAPPAS---SSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPP 167
V + P + ++APP PP + P SG T P P S PP AP P
Sbjct: 2459 VTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIP-SGLVFTHRPEP---SKPPIAPKP 2514
Query: 168 TPPSSGVPTTPPQAGGPPP 186
P T P P P
Sbjct: 2515 VIPQLPTTTQKPTDIHPKP 2533
Score = 50.1 bits (118), Expect = 7e-06
Identities = 50/170 (29%), Positives = 58/170 (34%), Gaps = 45/170 (26%)
Query: 70 QQPPPQQPPPQQPPPHQPPPHPQPHQQQ-------QPPPPPQDSSKPVVAQGPGPAPGVG 122
Q+ P Q P P P P+P + QPPPPP P P P
Sbjct: 2369 QEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPP-----------PPPPP--- 2414
Query: 123 SAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTP------------- 169
PP PP P PP + P PT P +T A P TP
Sbjct: 2415 --PPPPPPPPPPPP----LPPPTSPKPTILPKKKLTVASP-VTTATPLFDAVTTLETTAV 2467
Query: 170 -PSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKP 218
S+G+P T PPP P P P P P+ K P PKP
Sbjct: 2468 LRSNGLPVTRICTTAPPPVP---PKPSSIPSGLVFTHRPEPSKPPIAPKP 2514
Score = 48.1 bits (113), Expect = 3e-05
Identities = 48/169 (28%), Positives = 57/169 (33%), Gaps = 28/169 (16%)
Query: 47 MGPGPGQSGPKP---PIPPPP-PHQQQQQPPPQQPPPQQPPPHQ---------PPPHPQP 93
M P P + P P P PP P P Q P PQQ P Q + P QP
Sbjct: 862 MSPKP-DAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQP 920
Query: 94 HQQQQPPPPP----------QDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPP 143
Q+ Q S+ A PGP G P + P+ PPTS PP
Sbjct: 921 TTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPP 980
Query: 144 GS----GPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPP 188
S P P + P + P A P + PT PPP
Sbjct: 981 KSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPP 1029
Score = 47.4 bits (111), Expect = 5e-05
Identities = 56/204 (27%), Positives = 70/204 (34%), Gaps = 24/204 (11%)
Query: 45 GPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQ 104
GP GQ P P + Q + P+ P PP P+P Q P PQ
Sbjct: 835 GPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRP-TAGQTVPTPQ 893
Query: 105 DSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPT-SGAPPGSGPG---------PTPTPP 154
S KP Q + +GS A S P T +G G G T P
Sbjct: 894 QSPKP-QEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQP 952
Query: 155 PAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPA-AVPGPG---PGPKQGPGPGGPKGG 210
+ + PGAP P+ P+ PP + GPP A P P P K+ P K
Sbjct: 953 GPHSQSGPGAPMKQAPA---PSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEK-- 1007
Query: 211 KMPGGPKPGGGPGLSTPGGHPKPP 234
PK P + KPP
Sbjct: 1008 ---LEPKAEQAPTVKRTETEKKPP 1028
Score = 43.1 bits (100), Expect = 9e-04
Identities = 37/140 (26%), Positives = 50/140 (35%), Gaps = 21/140 (15%)
Query: 46 PMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQD 105
P P P P PP PPPPP PPP P P P +++ P
Sbjct: 2407 PPPPPPPPPPPPPPPPPPPP-----LPPPTSPKPTILP-----------KKKLTVASPVT 2450
Query: 106 SSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAV-TSAPPGA 164
++ P+ + + S+ P T + APP P P+ P V T P +
Sbjct: 2451 TATPLF----DAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPS 2506
Query: 165 PPPTPPSSGVPTTPPQAGGP 184
PP P +P P P
Sbjct: 2507 KPPIAPKPVIPQLPTTTQKP 2526
Score = 39.7 bits (91), Expect = 0.010
Identities = 53/197 (26%), Positives = 63/197 (31%), Gaps = 42/197 (21%)
Query: 49 PGP-GQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPH---QPPPHPQPH--QQQQPPPP 102
PGP QSGP P+ +Q P P QPP Q PP Q PP P +++ P
Sbjct: 952 PGPHSQSGPGAPM--------KQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAP 1003
Query: 103 PQDSSKPVVAQGPGP--APGVGSAPPASSSAPPATPPTSGAPPGS---GPGPTPTPPPAV 157
+ +P Q P PP S P P P P T P
Sbjct: 1004 AAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCK 1063
Query: 158 TSAPPGAPPPTPPSSGVPTTPPQ-----AGGPPPP---------------PAAVPGP-GP 196
T G+ P P+ T G P P A+ G G
Sbjct: 1064 TELNIGSKDP--PNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGD 1121
Query: 197 GPKQGPGPGGPKGGKMP 213
K P P GPK MP
Sbjct: 1122 IRKMPPAPSGPKASPMP 1138
Score = 39.3 bits (90), Expect = 0.013
Identities = 50/204 (24%), Positives = 65/204 (31%), Gaps = 24/204 (11%)
Query: 34 PPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQP 93
PP G ++ P P P P + Q+ ++P Q P+P
Sbjct: 807 PPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKP 866
Query: 94 HQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTP 153
+ P P+ S P PGP P G P +P + G
Sbjct: 867 DAK----PMPKGSPTP-----PGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLG------- 910
Query: 154 PPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAA--VPGPG-PGPKQGPGPGGP-KG 209
++T AP PT P V G A+ + G PGP GPG P K
Sbjct: 911 --SITDAPKS--QPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQ 966
Query: 210 GKMPGGPKPGGGPGLSTPGGHPKP 233
P P GP ST P P
Sbjct: 967 APAPSQPPTSQGPPKSTGQAPPAP 990
Score = 39.3 bits (90), Expect = 0.013
Identities = 26/115 (22%), Positives = 63/115 (54%), Gaps = 8/115 (6%)
Query: 455 DEDGLPEKLAQKNPMYQKERETPPRFAQHGTFEYEYSQRWKSLDEMEKQQREQVEKNMKD 514
+ED ++L + + + E+ RFA+ +E + QR++ +Q++ V+K +++
Sbjct: 3206 EEDKQQQQLDLERELLELEKIKQQRFAEELEWERQEIQRFR------EQEKIMVQKKLEE 3259
Query: 515 AKDKLESEMEDAYHEHQAN-LLRQDLMRRQE-ELRRMEELHNQEMQKRKEMQLRQ 567
+ + + E QA ++RQ+ + +Q+ +L ++++L Q Q+ +E ++RQ
Sbjct: 3260 LQSMKQHLLFQQEEERQAQFMMRQETLAQQQLQLEQIQQLQQQLHQQLEEQKIRQ 3314
Score = 30.4 bits (67), Expect = 5.9
Identities = 22/92 (23%), Positives = 43/92 (46%), Gaps = 6/92 (6%)
Query: 506 EQVEKNMKDAKDKLESEMEDAYHEHQANLLRQDLMRRQEELRRMEE-LHNQEMQKRKEMQ 564
E + + K + + + + + H L + +EELR EE L QE Q+ E Q
Sbjct: 1739 EDSDSSPSHKKGESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQ 1798
Query: 565 LRQEEERRRREEEMMIRQREMEEQMRRQREES 596
R+ ++ +++ + E+ Q RR+R ++
Sbjct: 1799 QRKSSSKKSKKD-----KDELRAQRRRERPKT 1825
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 100 bits (248), Expect = 6e-21
Identities = 90/266 (33%), Positives = 100/266 (37%), Gaps = 54/266 (20%)
Query: 46 PMGPGPGQSGPKPPIPPPPPHQQ----QQQPPPQQPPPQ----------QP----PPHQP 87
P P P + + P P PP QQ + QP P +PP Q QP PP QP
Sbjct: 296 PSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQP 355
Query: 88 P----PHPQPHQQQQPPPPPQDSSKPVVAQGPGPA-----PGVGSAPPASSSAPPATPPT 138
P P QP +PP S KP Q PGP PGVG P + PA PPT
Sbjct: 356 PGTTKPPAQPLGPAKPPAQQTGSEKPSSEQ-PGPKALAQPPGVGKTP--AQQPGPAKPPT 412
Query: 139 S--GAP-----------PGSGPGPTPTPP----PAVTSAPPGAPPPTPPSSGVPTTPP-Q 180
G P P PGPT TP P A P T PT PP Q
Sbjct: 413 QQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQ 472
Query: 181 AGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKP---GGGPGLSTP--GGHPKPPH 235
GP PP PGP P Q PG P + PG KP GP +P G KPP
Sbjct: 473 LPGPAKPPPQQPGPAKPPPQQPGSAKPP-SQQPGSTKPPPQQPGPAKPSPQQPGSTKPPS 531
Query: 236 RGGGEPRGGRQHHPPYHQQHHQGPPP 261
+ G + Q P Q P
Sbjct: 532 QQPGSAKPSAQQPSPAKPSAQQSTKP 557
Score = 97.8 bits (242), Expect = 3e-20
Identities = 78/232 (33%), Positives = 91/232 (39%), Gaps = 34/232 (14%)
Query: 56 PKPPIPPPPPHQQQQ--QPPPQQPPPQ--QPPPHQPPPHP---------QPHQQQQPPPP 102
P P P PP QQ +PP QQP + QP P +PP P QP + P P
Sbjct: 296 PSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQP 355
Query: 103 PQDSSKPVVAQGPG--PAPGVGSAPPASSSAPP---ATPPTSGAPPGSGPGPTPTPPPAV 157
P + P GP PA GS P+S P A PP G P PGP P V
Sbjct: 356 PGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQV 415
Query: 158 TSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPK 217
G P P G+ + P +A GP P PGPG P Q GPG +
Sbjct: 416 -----GTPKPLAQQPGLQS-PAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKP 469
Query: 218 PGGGPGLSTPG----GHPKPPHRGGGEPRGGRQHHPPYHQQHHQGPPPGGPG 265
P PG + P G KPP + G + PP Q PPP PG
Sbjct: 470 PSQLPGPAKPPPQQPGPAKPPPQQPGSAK------PPSQQPGSTKPPPQQPG 515
Score = 90.5 bits (223), Expect = 5e-18
Identities = 73/212 (34%), Positives = 81/212 (38%), Gaps = 25/212 (11%)
Query: 42 QNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPP------PQQPPPQQPPPHQ---PPPHPQ 92
Q GP P Q+G + P P + QPP QQP P +PP Q P P Q
Sbjct: 364 QPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQ 423
Query: 93 PHQQQQPPPPPQDSSKPVVAQGPG--PA----PGVGSAPPASSSAPPATPPTSGAPPGSG 146
Q P P + PV GPG PA PG SA + PP+ P PP
Sbjct: 424 QPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQ 483
Query: 147 PGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGG 206
PGP PP SA PP P S P PPQ GP P PG P Q PG
Sbjct: 484 PGPAKPPPQQPGSA---KPPSQQPGSTKP--PPQQPGPAKPSPQQPGSTKPPSQQPGSAK 538
Query: 207 PKGGKMPGGPKPGG----GPGLSTPGGHPKPP 234
P + P KP P T G P P
Sbjct: 539 P-SAQQPSPAKPSAQQSTKPVSQTGSGKPLQP 569
Score = 79.0 bits (193), Expect = 1e-14
Identities = 70/196 (35%), Positives = 81/196 (41%), Gaps = 25/196 (12%)
Query: 35 PPGMGLN--QNRGPMGPGPGQSG-PKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPP--- 88
PPG+G Q GP P Q G PKP P + P P + P QQP P + P
Sbjct: 394 PPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQ 453
Query: 89 --PHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPAS--SSAPPATPPTSGAPPG 144
P QQ P PP S P A+ P PG PP S+ PP+ P S PP
Sbjct: 454 AGPGKTSAQQTGPTKPP--SQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPP 511
Query: 145 SGPGPT-PTP-------PPAVT--SAPPGAPPPTP--PSSGVPTTPPQAGGPPPPPAAVP 192
PGP P+P PP+ SA P A P+P PS+ T P G P P
Sbjct: 512 QQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTG-SGKPLQPP 570
Query: 193 GPGPGPKQGPGPGGPK 208
P KQ P G PK
Sbjct: 571 TVSPSAKQPPSQGLPK 586
Score = 75.1 bits (183), Expect = 2e-13
Identities = 62/156 (39%), Positives = 70/156 (44%), Gaps = 20/156 (12%)
Query: 32 RSPPPGMGLNQNRGPMGPGPGQSGP-KPPI----PPPPPHQQ--QQQPPPQQPPPQQPPP 84
+ P PG Q GP Q+GP KPP P PP QQ +PPPQQP +PP
Sbjct: 442 QQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPS 501
Query: 85 HQPPPHPQPHQQQQP--PPPPQDSSKPVVAQGPGPA-PGVGSAPPASSSAPPATPPTSGA 141
QP P QQ P P P Q S +Q PG A P PA SA +T P S
Sbjct: 502 QQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVS-- 559
Query: 142 PPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTT 177
GSG P PP V+ P A PPS G+P T
Sbjct: 560 QTGSG---KPLQPPTVS---PSA--KQPPSQGLPKT 587
Score = 72.8 bits (177), Expect = 1e-12
Identities = 74/249 (29%), Positives = 89/249 (35%), Gaps = 68/249 (27%)
Query: 57 KPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPG 116
KPP+ PP +Q P + P QQ + QP + + PP + KP+ QGP
Sbjct: 208 KPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPP---GTGKPI--QGPT 262
Query: 117 PAPGVG------------------------SAPPA--SSSAPPATPPTSGAPPGSGPG-- 148
P S P+ S S PP PT G PP PG
Sbjct: 263 QTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHE 322
Query: 149 ---PTPTPPPAVTSA-------PPGA--PPPTPPSSGVPTTPPQAGGPPPPP-------- 188
P P PPA S PG PP PP + P P Q GP PP
Sbjct: 323 KSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKP--PAQPLGPAKPPAQQTGSEK 380
Query: 189 -----------AAVPGPGPGPKQGPGPGGPKGGKMPGGPKP-GGGPGLSTPGGHPKPPHR 236
A PG G P Q PGP P ++ G PKP PGL +P P P
Sbjct: 381 PSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQV-GTPKPLAQQPGLQSPAKAPGPTKT 439
Query: 237 GGGEPRGGR 245
+P G+
Sbjct: 440 PVQQPGPGK 448
Score = 68.6 bits (166), Expect = 2e-11
Identities = 50/128 (39%), Positives = 56/128 (43%), Gaps = 23/128 (17%)
Query: 41 NQNRGPMGPGPGQSGP-KPPIPPP----PPHQQ--QQQPPPQQPPPQQPPPHQP----PP 89
+Q GP P P Q GP KPP P PP QQ +PPPQQP P +P P QP PP
Sbjct: 471 SQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPP 530
Query: 90 HPQP----HQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGS 145
QP QQP P +KP Q P GS P PP P++ PP
Sbjct: 531 SQQPGSAKPSAQQPSP-----AKPSAQQSTKPVSQTGSGKPLQ---PPTVSPSAKQPPSQ 582
Query: 146 GPGPTPTP 153
G T P
Sbjct: 583 GLPKTICP 590
Score = 60.8 bits (146), Expect = 4e-09
Identities = 58/227 (25%), Positives = 74/227 (32%), Gaps = 48/227 (21%)
Query: 53 QSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPP--HQPPPHPQPHQQQQPPPPPQDSSKPV 110
+S P+P P +Q + P P++PPP QP H P + + PP SKP
Sbjct: 674 KSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPA 733
Query: 111 VAQGPGPAPGVGSAPPASS--SAPPATPPTSGAPPGSGPGPTPTPPPAVT-------SAP 161
+ P AP A P PT+ S P P + + P
Sbjct: 734 PPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTP 793
Query: 162 PGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPG--------PGP--------------- 198
P PS P T + P A+P P PGP
Sbjct: 794 PLKTDSAKPSQSFPPTGEKVS--PFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQK 851
Query: 199 ---------KQGPGPGG---PKGGKMPGGPKPGGGPGLSTPGGHPKP 233
K P P PKG P GP+P G + TP PKP
Sbjct: 852 KEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKP 898
Score = 59.3 bits (142), Expect = 1e-08
Identities = 51/165 (30%), Positives = 62/165 (37%), Gaps = 14/165 (8%)
Query: 49 PGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSK 108
P S P P P + QPPP PPP PPP P P PP PP S K
Sbjct: 2377 PSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPP--PPPPPPPPPPPPPPLPPPTSPK 2434
Query: 109 PVVAQGPGPAPGVGSAPPASSSAP----PATPPTSGAPPGSGPGPTPTPPPAVTSAPPGA 164
P + P + A P +++ P T T+ +G P T+ PP
Sbjct: 2435 PTIL----PKKKLTVASPVTTATPLFDAVTTLETTAVLRSNG---LPVTRICTTAPPPVP 2487
Query: 165 PPPTP-PSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPK 208
P P+ PS V T P+ PP P V P Q P PK
Sbjct: 2488 PKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPK 2532
Score = 58.9 bits (141), Expect = 2e-08
Identities = 47/139 (33%), Positives = 56/139 (40%), Gaps = 14/139 (10%)
Query: 53 QSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVA 112
Q P PP PPPPP PPP PPP PPP P P P ++ P ++ A
Sbjct: 2404 QPPPPPPPPPPPP-----PPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDA 2458
Query: 113 QGPGPAPGV--GSAPPAS---SSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPP 167
V + P + ++APP PP + P SG T P P S PP AP P
Sbjct: 2459 VTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIP-SGLVFTHRPEP---SKPPIAPKP 2514
Query: 168 TPPSSGVPTTPPQAGGPPP 186
P T P P P
Sbjct: 2515 VIPQLPTTTQKPTDIHPKP 2533
Score = 50.1 bits (118), Expect = 7e-06
Identities = 50/170 (29%), Positives = 58/170 (34%), Gaps = 45/170 (26%)
Query: 70 QQPPPQQPPPQQPPPHQPPPHPQPHQQQ-------QPPPPPQDSSKPVVAQGPGPAPGVG 122
Q+ P Q P P P P+P + QPPPPP P P P
Sbjct: 2369 QEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPP-----------PPPPP--- 2414
Query: 123 SAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTP------------- 169
PP PP P PP + P PT P +T A P TP
Sbjct: 2415 --PPPPPPPPPPPP----LPPPTSPKPTILPKKKLTVASP-VTTATPLFDAVTTLETTAV 2467
Query: 170 -PSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKP 218
S+G+P T PPP P P P P P+ K P PKP
Sbjct: 2468 LRSNGLPVTRICTTAPPPVP---PKPSSIPSGLVFTHRPEPSKPPIAPKP 2514
Score = 48.1 bits (113), Expect = 3e-05
Identities = 48/169 (28%), Positives = 57/169 (33%), Gaps = 28/169 (16%)
Query: 47 MGPGPGQSGPKP---PIPPPP-PHQQQQQPPPQQPPPQQPPPHQ---------PPPHPQP 93
M P P + P P P PP P P Q P PQQ P Q + P QP
Sbjct: 862 MSPKP-DAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQP 920
Query: 94 HQQQQPPPPP----------QDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPP 143
Q+ Q S+ A PGP G P + P+ PPTS PP
Sbjct: 921 TTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPP 980
Query: 144 GS----GPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPP 188
S P P + P + P A P + PT PPP
Sbjct: 981 KSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPP 1029
Score = 47.4 bits (111), Expect = 5e-05
Identities = 56/204 (27%), Positives = 70/204 (34%), Gaps = 24/204 (11%)
Query: 45 GPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQ 104
GP GQ P P + Q + P+ P PP P+P Q P PQ
Sbjct: 835 GPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRP-TAGQTVPTPQ 893
Query: 105 DSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPT-SGAPPGSGPG---------PTPTPP 154
S KP Q + +GS A S P T +G G G T P
Sbjct: 894 QSPKP-QEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQP 952
Query: 155 PAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPA-AVPGPG---PGPKQGPGPGGPKGG 210
+ + PGAP P+ P+ PP + GPP A P P P K+ P K
Sbjct: 953 GPHSQSGPGAPMKQAPA---PSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEK-- 1007
Query: 211 KMPGGPKPGGGPGLSTPGGHPKPP 234
PK P + KPP
Sbjct: 1008 ---LEPKAEQAPTVKRTETEKKPP 1028
Score = 43.1 bits (100), Expect = 9e-04
Identities = 37/140 (26%), Positives = 50/140 (35%), Gaps = 21/140 (15%)
Query: 46 PMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQD 105
P P P P PP PPPPP PPP P P P +++ P
Sbjct: 2407 PPPPPPPPPPPPPPPPPPPP-----LPPPTSPKPTILP-----------KKKLTVASPVT 2450
Query: 106 SSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAV-TSAPPGA 164
++ P+ + + S+ P T + APP P P+ P V T P +
Sbjct: 2451 TATPLF----DAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPS 2506
Query: 165 PPPTPPSSGVPTTPPQAGGP 184
PP P +P P P
Sbjct: 2507 KPPIAPKPVIPQLPTTTQKP 2526
Score = 39.7 bits (91), Expect = 0.010
Identities = 53/197 (26%), Positives = 63/197 (31%), Gaps = 42/197 (21%)
Query: 49 PGP-GQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPH---QPPPHPQPH--QQQQPPPP 102
PGP QSGP P+ +Q P P QPP Q PP Q PP P +++ P
Sbjct: 952 PGPHSQSGPGAPM--------KQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAP 1003
Query: 103 PQDSSKPVVAQGPGP--APGVGSAPPASSSAPPATPPTSGAPPGS---GPGPTPTPPPAV 157
+ +P Q P PP S P P P P T P
Sbjct: 1004 AAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCK 1063
Query: 158 TSAPPGAPPPTPPSSGVPTTPPQ-----AGGPPPP---------------PAAVPGP-GP 196
T G+ P P+ T G P P A+ G G
Sbjct: 1064 TELNIGSKDP--PNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGD 1121
Query: 197 GPKQGPGPGGPKGGKMP 213
K P P GPK MP
Sbjct: 1122 IRKMPPAPSGPKASPMP 1138
Score = 39.3 bits (90), Expect = 0.013
Identities = 50/204 (24%), Positives = 65/204 (31%), Gaps = 24/204 (11%)
Query: 34 PPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQP 93
PP G ++ P P P P + Q+ ++P Q P+P
Sbjct: 807 PPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKP 866
Query: 94 HQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTP 153
+ P P+ S P PGP P G P +P + G
Sbjct: 867 DAK----PMPKGSPTP-----PGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLG------- 910
Query: 154 PPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAA--VPGPG-PGPKQGPGPGGP-KG 209
++T AP PT P V G A+ + G PGP GPG P K
Sbjct: 911 --SITDAPKS--QPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQ 966
Query: 210 GKMPGGPKPGGGPGLSTPGGHPKP 233
P P GP ST P P
Sbjct: 967 APAPSQPPTSQGPPKSTGQAPPAP 990
Score = 39.3 bits (90), Expect = 0.013
Identities = 26/115 (22%), Positives = 63/115 (54%), Gaps = 8/115 (6%)
Query: 455 DEDGLPEKLAQKNPMYQKERETPPRFAQHGTFEYEYSQRWKSLDEMEKQQREQVEKNMKD 514
+ED ++L + + + E+ RFA+ +E + QR++ +Q++ V+K +++
Sbjct: 3206 EEDKQQQQLDLERELLELEKIKQQRFAEELEWERQEIQRFR------EQEKIMVQKKLEE 3259
Query: 515 AKDKLESEMEDAYHEHQAN-LLRQDLMRRQE-ELRRMEELHNQEMQKRKEMQLRQ 567
+ + + E QA ++RQ+ + +Q+ +L ++++L Q Q+ +E ++RQ
Sbjct: 3260 LQSMKQHLLFQQEEERQAQFMMRQETLAQQQLQLEQIQQLQQQLHQQLEEQKIRQ 3314
Score = 30.4 bits (67), Expect = 5.9
Identities = 22/92 (23%), Positives = 43/92 (46%), Gaps = 6/92 (6%)
Query: 506 EQVEKNMKDAKDKLESEMEDAYHEHQANLLRQDLMRRQEELRRMEE-LHNQEMQKRKEMQ 564
E + + K + + + + + H L + +EELR EE L QE Q+ E Q
Sbjct: 1739 EDSDSSPSHKKGESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQ 1798
Query: 565 LRQEEERRRREEEMMIRQREMEEQMRRQREES 596
R+ ++ +++ + E+ Q RR+R ++
Sbjct: 1799 QRKSSSKKSKKD-----KDELRAQRRRERPKT 1825
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.137 0.425
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 50,216,398
Number of Sequences: 37866
Number of extensions: 4921797
Number of successful extensions: 206100
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 2734
Number of HSP's successfully gapped in prelim test: 3287
Number of HSP's that attempted gapping in prelim test: 28024
Number of HSP's gapped (non-prelim): 60012
length of query: 707
length of database: 18,247,518
effective HSP length: 109
effective length of query: 598
effective length of database: 14,120,124
effective search space: 8443834152
effective search space used: 8443834152
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.