BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|13375997 dehydrogenase/reductase (SDR family) member 12 isoform 2 [Homo sapiens] (242 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|13375997 dehydrogenase/reductase (SDR family) member 12 isofo... 495 e-140 gi|72534732 dehydrogenase/reductase (SDR family) member 12 isofo... 382 e-106 gi|166795268 retinol dehydrogenase 11 [Homo sapiens] 85 6e-17 gi|186928839 retinol dehydrogenase 12 [Homo sapiens] 82 4e-16 gi|193804850 dehydrogenase/reductase (SDR family) X-linked [Homo... 78 8e-15 gi|225579078 retinol dehydrogenase 13 isoform 1 [Homo sapiens] 74 9e-14 gi|19923931 retinol dehydrogenase 13 isoform 2 [Homo sapiens] 74 9e-14 gi|10190746 retinol dehydrogenase 14 (all-trans and 9-cis) [Homo... 70 1e-12 gi|7706523 WW domain-containing oxidoreductase isoform 1 [Homo s... 47 1e-05 gi|142976729 estradiol 17-beta-dehydrogenase 11 [Homo sapiens] 45 6e-05 gi|210032110 hydroxysteroid (17-beta) dehydrogenase 13 isoform A... 45 7e-05 gi|146231950 dehydrogenase/reductase (SDR family) member 13 [Hom... 42 4e-04 gi|50726952 retinol dehydrogenase 5 (11-cis and 9-cis) [Homo sap... 40 0.001 gi|40548397 NADP-dependent retinol dehydrogenase/reductase [Homo... 37 0.012 gi|214010158 NADP-dependent retinol dehydrogenase/reductase [Hom... 37 0.012 gi|214010156 NADP-dependent retinol dehydrogenase/reductase [Hom... 37 0.012 gi|22758144 NADP-dependent retinol dehydrogenase/reductase [Homo... 37 0.012 gi|40254986 hydroxysteroid dehydrogenase like 2 [Homo sapiens] 37 0.020 gi|223646115 short chain dehydrogenase/reductase family 16C, mem... 36 0.034 gi|210032112 hydroxysteroid (17-beta) dehydrogenase 13 isoform B... 35 0.077 gi|40807363 epidermal retinal dehydrogenase 2 [Homo sapiens] 34 0.13 gi|38679977 acetyl-Coenzyme A carboxylase alpha isoform 2 [Homo ... 33 0.17 gi|38679974 acetyl-Coenzyme A carboxylase alpha isoform 4 [Homo ... 33 0.17 gi|38679971 acetyl-Coenzyme A carboxylase alpha isoform 3 [Homo ... 33 0.17 gi|38679967 acetyl-Coenzyme A carboxylase alpha isoform 2 [Homo ... 33 0.17 gi|38679960 acetyl-Coenzyme A carboxylase alpha isoform 1 [Homo ... 33 0.17 gi|7705421 hydroxysteroid (17-beta) dehydrogenase 7 [Homo sapiens] 33 0.29 gi|22507405 short chain dehydrogenase/reductase family 9C, membe... 30 1.4 gi|119392083 hydroxysteroid (11-beta) dehydrogenase 2 [Homo sapi... 30 1.9 gi|226371731 hydroxysteroid dehydrogenase like 1 isoform a [Homo... 30 2.5 >gi|13375997 dehydrogenase/reductase (SDR family) member 12 isoform 2 [Homo sapiens] Length = 242 Score = 495 bits (1275), Expect = e-140 Identities = 242/242 (100%), Positives = 242/242 (100%) Query: 1 MNLHVKTLSLMTWRSRFLEESFWSLEETAALAKQLPLKSPSENIFLHIVDLSDPKQIWKF 60 MNLHVKTLSLMTWRSRFLEESFWSLEETAALAKQLPLKSPSENIFLHIVDLSDPKQIWKF Sbjct: 1 MNLHVKTLSLMTWRSRFLEESFWSLEETAALAKQLPLKSPSENIFLHIVDLSDPKQIWKF 60 Query: 61 VENFKQEHKLHVLINNAGCMVNKRELTEDGLEKNFAANTLGVYILTTGLIPVLEKEHDPR 120 VENFKQEHKLHVLINNAGCMVNKRELTEDGLEKNFAANTLGVYILTTGLIPVLEKEHDPR Sbjct: 61 VENFKQEHKLHVLINNAGCMVNKRELTEDGLEKNFAANTLGVYILTTGLIPVLEKEHDPR 120 Query: 121 VITVSSGGMLVQKLNTNDLQSERTPFDGTMVYAQNKRQQVVLTERWAQGHPAIHFSSMHP 180 VITVSSGGMLVQKLNTNDLQSERTPFDGTMVYAQNKRQQVVLTERWAQGHPAIHFSSMHP Sbjct: 121 VITVSSGGMLVQKLNTNDLQSERTPFDGTMVYAQNKRQQVVLTERWAQGHPAIHFSSMHP 180 Query: 181 GWADTPGVRQAMPGFHARFGDRLRSEAQGADTMLWLALSSAAAAQPSGRFFQGDFLPGCE 240 GWADTPGVRQAMPGFHARFGDRLRSEAQGADTMLWLALSSAAAAQPSGRFFQGDFLPGCE Sbjct: 181 GWADTPGVRQAMPGFHARFGDRLRSEAQGADTMLWLALSSAAAAQPSGRFFQGDFLPGCE 240 Query: 241 GS 242 GS Sbjct: 241 GS 242 >gi|72534732 dehydrogenase/reductase (SDR family) member 12 isoform 1 [Homo sapiens] Length = 271 Score = 382 bits (980), Expect = e-106 Identities = 186/186 (100%), Positives = 186/186 (100%) Query: 1 MNLHVKTLSLMTWRSRFLEESFWSLEETAALAKQLPLKSPSENIFLHIVDLSDPKQIWKF 60 MNLHVKTLSLMTWRSRFLEESFWSLEETAALAKQLPLKSPSENIFLHIVDLSDPKQIWKF Sbjct: 1 MNLHVKTLSLMTWRSRFLEESFWSLEETAALAKQLPLKSPSENIFLHIVDLSDPKQIWKF 60 Query: 61 VENFKQEHKLHVLINNAGCMVNKRELTEDGLEKNFAANTLGVYILTTGLIPVLEKEHDPR 120 VENFKQEHKLHVLINNAGCMVNKRELTEDGLEKNFAANTLGVYILTTGLIPVLEKEHDPR Sbjct: 61 VENFKQEHKLHVLINNAGCMVNKRELTEDGLEKNFAANTLGVYILTTGLIPVLEKEHDPR 120 Query: 121 VITVSSGGMLVQKLNTNDLQSERTPFDGTMVYAQNKRQQVVLTERWAQGHPAIHFSSMHP 180 VITVSSGGMLVQKLNTNDLQSERTPFDGTMVYAQNKRQQVVLTERWAQGHPAIHFSSMHP Sbjct: 121 VITVSSGGMLVQKLNTNDLQSERTPFDGTMVYAQNKRQQVVLTERWAQGHPAIHFSSMHP 180 Query: 181 GWADTP 186 GWADTP Sbjct: 181 GWADTP 186 >gi|166795268 retinol dehydrogenase 11 [Homo sapiens] Length = 318 Score = 84.7 bits (208), Expect = 6e-17 Identities = 60/200 (30%), Positives = 104/200 (52%), Gaps = 6/200 (3%) Query: 25 LEETAALAKQLPLKSPSENIFLHIVDLSDPKQIWKFVENFKQEHK-LHVLINNAGCMVNK 83 +E+ +AK++ + ++ + + +DLSD K I F + F E K LHVLINNAG M+ Sbjct: 75 VEKGELVAKEIQTTTGNQQVLVRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCP 134 Query: 84 RELTEDGLEKNFAANTLGVYILTTGLIPVLEKEHDPRVITVSSGGMLVQKLNTNDLQSER 143 T DG E + N LG ++LT L+ L++ R++ VSS + +++ ++LQ E+ Sbjct: 135 YSKTADGFEMHIGVNHLGHFLLTHLLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEK 194 Query: 144 TPFDGTMVYAQNKRQQVVLTERWAQ--GHPAIHFSSMHPGWADTPGVRQA--MPGFHARF 199 ++ + Y +K ++ T+ A+ + S+HPG + VR + M F Sbjct: 195 F-YNAGLAYCHSKLANILFTQELARRLKGSGVTTYSVHPGTVQSELVRHSSFMRWMWWLF 253 Query: 200 GDRLRSEAQGADTMLWLALS 219 +++ QGA T L AL+ Sbjct: 254 SFFIKTPQQGAQTSLHCALT 273 >gi|186928839 retinol dehydrogenase 12 [Homo sapiens] Length = 316 Score = 82.0 bits (201), Expect = 4e-16 Identities = 67/207 (32%), Positives = 103/207 (49%), Gaps = 11/207 (5%) Query: 32 AKQLPLKSPSENIFLHIVDLSDPKQIWKFVENFKQEHK-LHVLINNAGCMVNKRELTEDG 90 A ++ + + + + + +DLSD K I F E F E K LH+LINNAG M+ T DG Sbjct: 80 ASEIRVDTKNSQVLVRKLDLSDTKSIRAFAEGFLAEEKQLHILINNAGVMMCPYSKTADG 139 Query: 91 LEKNFAANTLGVYILTTGLIPVLEKEHDPRVITVSSGGMLVQKLNTNDLQSERTPFDGTM 150 E + N LG ++LT L+ L+ RV+ VSS + K+ +DLQSE+ + Sbjct: 140 FETHLGVNHLGHFLLTYLLLERLKVSAPARVVNVSSVAHHIGKIPFHDLQSEKR-YSRGF 198 Query: 151 VYAQNKRQQVVLTERWA---QGHPAIHFSSMHPGWADTPGVRQA--MPGFHARFGDRLRS 205 Y +K V+ T A QG + ++HPG + VR + + F +++ Sbjct: 199 AYCHSKLANVLFTRELAKRLQG-TGVTTYAVHPGVVRSELVRHSSLLCLLWRLFSPFVKT 257 Query: 206 EAQGADTMLWLALSSAAAAQP-SGRFF 231 +GA T L AL A +P SG++F Sbjct: 258 AREGAQTSLHCAL--AEGLEPLSGKYF 282 >gi|193804850 dehydrogenase/reductase (SDR family) X-linked [Homo sapiens] Length = 330 Score = 77.8 bits (190), Expect = 8e-15 Identities = 56/142 (39%), Positives = 78/142 (54%), Gaps = 12/142 (8%) Query: 32 AKQLPLKSPSENI-----FLHIVDLSDPKQIWKFVENFKQEH-KLHVLINNAGCMVNKRE 85 AKQ+ K E + FL+ DL+ I +FV+ FK + LHVLINNAG M+ + Sbjct: 80 AKQVVSKIKEETLNDKVEFLYC-DLASMTSIRQFVQKFKMKKIPLHVLINNAGVMMVPQR 138 Query: 86 LTEDGLEKNFAANTLGVYILTTGLIPVLEKE----HDPRVITVSSGGMLVQKLNTNDLQS 141 T DG E++F N LG ++LT L+ L++ H RV+TVSS V +LN +DLQS Sbjct: 139 KTRDGFEEHFGLNYLGHFLLTNLLLDTLKESGSPGHSARVVTVSSATHYVAELNMDDLQS 198 Query: 142 ERTPFDGTMVYAQNKRQQVVLT 163 + YAQ+K V+ T Sbjct: 199 SAC-YSPHAAYAQSKLALVLFT 219 >gi|225579078 retinol dehydrogenase 13 isoform 1 [Homo sapiens] Length = 331 Score = 74.3 bits (181), Expect = 9e-14 Identities = 63/208 (30%), Positives = 101/208 (48%), Gaps = 13/208 (6%) Query: 25 LEETAALAKQLPLKSPSENIFLHIVDLSDPKQIWKFVENF-KQEHKLHVLINNAGCMVNK 83 +E+ A AK + ++ + ++ +DL+ K I +F ++E ++ +LINNAG M Sbjct: 72 MEKCEAAAKDIRGETLNHHVNARHLDLASLKSIREFAAKIIEEEERVDILINNAGVMRCP 131 Query: 84 RELTEDGLEKNFAANTLGVYILTTGLIPVLEKEHDPRVITVSSGGMLVQKLNTNDLQSER 143 TEDG E F N LG ++LT L+ L+ R+I +SS + ++ +DL + Sbjct: 132 HWTTEDGFEMQFGVNHLGHFLLTNLLLDKLKASAPSRIINLSSLAHVAGHIDFDDLNWQT 191 Query: 144 TPFDGTMVYAQNKRQQVVLTE---RWAQGHPAIHFSSMHPGWADTPGVRQAMPGFHARFG 200 ++ Y Q+K V+ T+ R QG + +++HPG A T R G H G Sbjct: 192 RKYNTKAAYCQSKLAIVLFTKELSRRLQG-SGVTVNALHPGVARTELGRHT--GIH---G 245 Query: 201 DRLRSEAQGADTMLWLALSS-AAAAQPS 227 S G + WL + S AAQPS Sbjct: 246 STFSSTTLG--PIFWLLVKSPELAAQPS 271 >gi|19923931 retinol dehydrogenase 13 isoform 2 [Homo sapiens] Length = 260 Score = 74.3 bits (181), Expect = 9e-14 Identities = 63/208 (30%), Positives = 101/208 (48%), Gaps = 13/208 (6%) Query: 25 LEETAALAKQLPLKSPSENIFLHIVDLSDPKQIWKFVENF-KQEHKLHVLINNAGCMVNK 83 +E+ A AK + ++ + ++ +DL+ K I +F ++E ++ +LINNAG M Sbjct: 1 MEKCEAAAKDIRGETLNHHVNARHLDLASLKSIREFAAKIIEEEERVDILINNAGVMRCP 60 Query: 84 RELTEDGLEKNFAANTLGVYILTTGLIPVLEKEHDPRVITVSSGGMLVQKLNTNDLQSER 143 TEDG E F N LG ++LT L+ L+ R+I +SS + ++ +DL + Sbjct: 61 HWTTEDGFEMQFGVNHLGHFLLTNLLLDKLKASAPSRIINLSSLAHVAGHIDFDDLNWQT 120 Query: 144 TPFDGTMVYAQNKRQQVVLTE---RWAQGHPAIHFSSMHPGWADTPGVRQAMPGFHARFG 200 ++ Y Q+K V+ T+ R QG + +++HPG A T R G H G Sbjct: 121 RKYNTKAAYCQSKLAIVLFTKELSRRLQG-SGVTVNALHPGVARTELGRHT--GIH---G 174 Query: 201 DRLRSEAQGADTMLWLALSS-AAAAQPS 227 S G + WL + S AAQPS Sbjct: 175 STFSSTTLG--PIFWLLVKSPELAAQPS 200 >gi|10190746 retinol dehydrogenase 14 (all-trans and 9-cis) [Homo sapiens] Length = 336 Score = 70.5 bits (171), Expect = 1e-12 Identities = 57/192 (29%), Positives = 93/192 (48%), Gaps = 11/192 (5%) Query: 49 VDLSDPKQIWKFVENFKQEH-KLHVLINNAGCMVNKRELTEDGLEKNFAANTLGVYILTT 107 +DL+ + + F + QE +L VLINNAG TEDG E F N LG ++LT Sbjct: 114 LDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTEDGFEMQFGVNHLGHFLLTN 173 Query: 108 GLIPVLEKEHDPRVITVSSGGMLVQKLNTNDLQSERTPFDGTMVYAQNKRQQVVLTERWA 167 L+ +L+ R++ VSS +N +DL SE++ ++ + Y+++K ++ T A Sbjct: 174 LLLGLLKSSAPSRIVVVSSKLYKYGDINFDDLNSEQS-YNKSFCYSRSKLANILFTRELA 232 Query: 168 QGHPA--IHFSSMHPGWADTPGVRQ------AMPGFHARFGDRLRSEAQGADTMLWLALS 219 + + + +HPG T R P F+ ++ +GA T ++LA S Sbjct: 233 RRLEGTNVTVNVLHPGIVRTNLGRHIHIPLLVKPLFNLVSWAFFKTPVEGAQTSIYLA-S 291 Query: 220 SAAAAQPSGRFF 231 S SGR+F Sbjct: 292 SPEVEGVSGRYF 303 >gi|7706523 WW domain-containing oxidoreductase isoform 1 [Homo sapiens] Length = 414 Score = 47.4 bits (111), Expect = 1e-05 Identities = 32/79 (40%), Positives = 42/79 (53%), Gaps = 1/79 (1%) Query: 49 VDLSDPKQIWKFVENFKQEH-KLHVLINNAGCMVNKRELTEDGLEKNFAANTLGVYILTT 107 +DL+ + + F E FK ++ LHVL+ NA LT+DGLE F N LG + L Sbjct: 182 LDLALLRSVQHFAEAFKAKNVPLHVLVCNAATFALPWSLTKDGLETTFQVNHLGHFYLVQ 241 Query: 108 GLIPVLEKEHDPRVITVSS 126 L VL + RVI VSS Sbjct: 242 LLQDVLCRSAPARVIVVSS 260 >gi|142976729 estradiol 17-beta-dehydrogenase 11 [Homo sapiens] Length = 300 Score = 45.1 bits (105), Expect = 6e-05 Identities = 33/105 (31%), Positives = 52/105 (49%), Gaps = 8/105 (7%) Query: 25 LEETAALAKQLPLKSPSENIFLHIVDLSDPKQIWKFVENFKQE-HKLHVLINNAGCMVNK 83 LEETAA K L K + +VD S+ + I+ + K E + +L+NNAG + Sbjct: 73 LEETAAKCKGLGAK-----VHTFVVDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTS 127 Query: 84 REL-TEDG-LEKNFAANTLGVYILTTGLIPVLEKEHDPRVITVSS 126 T+D +EK F N L + T +P + K + ++TV+S Sbjct: 128 DLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVAS 172 >gi|210032110 hydroxysteroid (17-beta) dehydrogenase 13 isoform A [Homo sapiens] Length = 300 Score = 44.7 bits (104), Expect = 7e-05 Identities = 28/105 (26%), Positives = 61/105 (58%), Gaps = 8/105 (7%) Query: 25 LEETAALAKQLPLKSPSENIFLHIVDLSDPKQIWKFVENFKQE-HKLHVLINNAGCMVNK 83 +EETAA ++L + + + ++VD S+ ++I++ + K+E + +++NNAG + Sbjct: 73 VEETAAECRKLGVTAHA-----YVVDCSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPA 127 Query: 84 RELT--EDGLEKNFAANTLGVYILTTGLIPVLEKEHDPRVITVSS 126 L+ ++ + K F N LG + +T L+P + + + ++TV+S Sbjct: 128 DLLSTKDEEITKTFEVNILGHFWITKALLPSMMERNHGHIVTVAS 172 >gi|146231950 dehydrogenase/reductase (SDR family) member 13 [Homo sapiens] Length = 377 Score = 42.4 bits (98), Expect = 4e-04 Identities = 54/217 (24%), Positives = 88/217 (40%), Gaps = 12/217 (5%) Query: 24 SLEETAALAKQLPLKSPSENIFLHIVDLSDPKQIWKFVENF-KQEHKLHVLINNAGCMVN 82 S E A A L +S + + +DL+ + F F E +L +LI+NAG ++ Sbjct: 69 SQERGEAAAFDLRQESGNNEVIFMALDLASLASVRAFATAFLSSEPRLDILIHNAG--IS 126 Query: 83 KRELTEDGLEKNFAANTLGVYILTTGLIPVLEKEHDPRVITVSSGGMLVQKLNTNDLQSE 142 T + N +G ++LT L+P L+ RV+ V+S +L+ L Sbjct: 127 SCGRTREAFNLLLRVNHIGPFLLTHLLLPCLKACAPSRVVVVASAAHCRGRLDFKRLDRP 186 Query: 143 RTPFDGTM-VYAQNKRQQVVLTERWAQGHPA--IHFSSMHPGWADTPGVRQAMPGF---- 195 + + YA K V+ A A + + HPG ++ + +PG+ Sbjct: 187 VVGWRQELRAYADTKLANVLFARELANQLEATGVTCYAAHPGPVNSELFLRHVPGWLRPL 246 Query: 196 -HARFGDRLRSEAQGADTMLWLALSSAAAAQPSGRFF 231 LR+ GA T L+ AL SGR+F Sbjct: 247 LRPLAWLVLRAPRGGAQTPLYCALQEGIEPL-SGRYF 282 >gi|50726952 retinol dehydrogenase 5 (11-cis and 9-cis) [Homo sapiens] Length = 318 Score = 40.4 bits (93), Expect = 0.001 Identities = 42/161 (26%), Positives = 69/161 (42%), Gaps = 37/161 (22%) Query: 41 SENIFLHIVDLSDPKQIW---KFVENFKQEHKLHVLINN---AGCMVNKRELTEDGLEKN 94 S + ++D++DP+ + K+VE +E L L+NN AG + LT D ++ Sbjct: 73 SSRLHTTLLDITDPQSVQQAAKWVEMHVKEAGLFGLVNNAGVAGIIGPTPWLTRDDFQRV 132 Query: 95 FAANTLGVYILTTGLIPVLEKEHDPRVITVSS---------GGMLVQKLNTNDLQSERTP 145 NT+G +T L+P+L++ RVI ++S GG V K Sbjct: 133 LNVNTMGPIGVTLALLPLLQQARG-RVINITSVLGRLAANGGGYCVSKF----------- 180 Query: 146 FDGTMVYAQNKRQQVVLTERWAQGHPAIHFSSMHPGWADTP 186 G ++ + R+ V H I S + PG+ TP Sbjct: 181 --GLEAFSDSLRRDV--------AHFGIRVSIVEPGFFRTP 211 >gi|40548397 NADP-dependent retinol dehydrogenase/reductase [Homo sapiens] Length = 319 Score = 37.4 bits (85), Expect = 0.012 Identities = 30/107 (28%), Positives = 50/107 (46%), Gaps = 4/107 (3%) Query: 25 LEETAALAKQLPLKSPSENIFLHIVDLSDPKQIWKFVENFKQEHKLHVLINNA---GCMV 81 L E+ + A + + L + D + K+ ++V+N E L LINNA G + Sbjct: 61 LTESGSTALKAETSERLRTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLA 120 Query: 82 NKRELTEDGLEKNFAANTLGVYILTTGLIPVLEKEHDPRVITVSSGG 128 LT + + N G+ +T ++P+++K RVI VSS G Sbjct: 121 PTDWLTLEDYREPIEVNLFGLISVTLNMLPLVKKAQG-RVINVSSVG 166 >gi|214010158 NADP-dependent retinol dehydrogenase/reductase [Homo sapiens] Length = 319 Score = 37.4 bits (85), Expect = 0.012 Identities = 30/107 (28%), Positives = 50/107 (46%), Gaps = 4/107 (3%) Query: 25 LEETAALAKQLPLKSPSENIFLHIVDLSDPKQIWKFVENFKQEHKLHVLINNA---GCMV 81 L E+ + A + + L + D + K+ ++V+N E L LINNA G + Sbjct: 61 LTESGSTALKAETSERLRTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLA 120 Query: 82 NKRELTEDGLEKNFAANTLGVYILTTGLIPVLEKEHDPRVITVSSGG 128 LT + + N G+ +T ++P+++K RVI VSS G Sbjct: 121 PTDWLTLEDYREPIEVNLFGLISVTLNMLPLVKKAQG-RVINVSSVG 166 >gi|214010156 NADP-dependent retinol dehydrogenase/reductase [Homo sapiens] Length = 319 Score = 37.4 bits (85), Expect = 0.012 Identities = 30/107 (28%), Positives = 50/107 (46%), Gaps = 4/107 (3%) Query: 25 LEETAALAKQLPLKSPSENIFLHIVDLSDPKQIWKFVENFKQEHKLHVLINNA---GCMV 81 L E+ + A + + L + D + K+ ++V+N E L LINNA G + Sbjct: 61 LTESGSTALKAETSERLRTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLA 120 Query: 82 NKRELTEDGLEKNFAANTLGVYILTTGLIPVLEKEHDPRVITVSSGG 128 LT + + N G+ +T ++P+++K RVI VSS G Sbjct: 121 PTDWLTLEDYREPIEVNLFGLISVTLNMLPLVKKAQG-RVINVSSVG 166 >gi|22758144 NADP-dependent retinol dehydrogenase/reductase [Homo sapiens] Length = 319 Score = 37.4 bits (85), Expect = 0.012 Identities = 30/107 (28%), Positives = 50/107 (46%), Gaps = 4/107 (3%) Query: 25 LEETAALAKQLPLKSPSENIFLHIVDLSDPKQIWKFVENFKQEHKLHVLINNA---GCMV 81 L E+ + A + + L + D + K+ ++V+N E L LINNA G + Sbjct: 61 LTESGSTALKAETSERLRTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLA 120 Query: 82 NKRELTEDGLEKNFAANTLGVYILTTGLIPVLEKEHDPRVITVSSGG 128 LT + + N G+ +T ++P+++K RVI VSS G Sbjct: 121 PTDWLTLEDYREPIEVNLFGLISVTLNMLPLVKKAQG-RVINVSSVG 166 >gi|40254986 hydroxysteroid dehydrogenase like 2 [Homo sapiens] Length = 418 Score = 36.6 bits (83), Expect = 0.020 Identities = 24/81 (29%), Positives = 39/81 (48%), Gaps = 3/81 (3%) Query: 48 IVDLSDPKQIWKFVEN-FKQEHKLHVLINNAGC--MVNKRELTEDGLEKNFAANTLGVYI 104 IVD+ D +QI VE K+ + +L+NNA + N + L+ NT G Y+ Sbjct: 72 IVDVRDEQQISAAVEKAIKKFGGIDILVNNASAISLTNTLDTPTKRLDLMMNVNTRGTYL 131 Query: 105 LTTGLIPVLEKEHDPRVITVS 125 + IP L+K ++ +S Sbjct: 132 ASKACIPYLKKSKVAHILNIS 152 >gi|223646115 short chain dehydrogenase/reductase family 16C, member 6 [Homo sapiens] Length = 323 Score = 35.8 bits (81), Expect = 0.034 Identities = 22/103 (21%), Positives = 52/103 (50%), Gaps = 7/103 (6%) Query: 27 ETAALAKQLPLKSPSENIFLHIVDLSDPKQIWKFVENFKQEH-KLHVLINNAGCMVNKR- 84 ET LAK+ + +F + D S+ +++++ + ++E + +L+NNA + K Sbjct: 75 ETCRLAKE----KGGKKVFPYTCDCSNRQEVYRVADQVRKEFGDVTILVNNADLVTGKPF 130 Query: 85 -ELTEDGLEKNFAANTLGVYILTTGLIPVLEKEHDPRVITVSS 126 ++ + +EK+F N + + +P + K + ++ +SS Sbjct: 131 LDIPDHMVEKSFLVNAITHFWTCKAFLPAVIKANHGHLVCISS 173 >gi|210032112 hydroxysteroid (17-beta) dehydrogenase 13 isoform B [Homo sapiens] Length = 264 Score = 34.7 bits (78), Expect = 0.077 Identities = 18/72 (25%), Positives = 39/72 (54%), Gaps = 2/72 (2%) Query: 57 IWKFVENFKQEHKLHVLINNAGCMVNKRELT--EDGLEKNFAANTLGVYILTTGLIPVLE 114 +W + K+ + +++NNAG + L+ ++ + K F N LG + +T L+P + Sbjct: 65 LWDINKVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNILGHFWITKALLPSMM 124 Query: 115 KEHDPRVITVSS 126 + + ++TV+S Sbjct: 125 ERNHGHIVTVAS 136 >gi|40807363 epidermal retinal dehydrogenase 2 [Homo sapiens] Length = 309 Score = 33.9 bits (76), Expect = 0.13 Identities = 27/111 (24%), Positives = 52/111 (46%), Gaps = 14/111 (12%) Query: 26 EETAALAKQLPLKSPSENIFLHIVDLSDPKQIWKFVENFKQE-HKLHVLINNAGCMVNKR 84 EET +A++ + + + + D S + +++ + K+E + +LINNAG + K+ Sbjct: 78 EETCKMARE----AGATRVHAYTCDCSQKEGVYRVADQVKKEVGDVSILINNAGIVTGKK 133 Query: 85 ------ELTEDGLEKNFAANTLGVYILTTGLIPVLEKEHDPRVITVSSGGM 129 EL E + NF A+ ++ L ++ +H V SS G+ Sbjct: 134 FLDCPDELMEKSFDVNFKAH---LWTYKAFLPAMIANDHGHLVCISSSAGL 181 >gi|38679977 acetyl-Coenzyme A carboxylase alpha isoform 2 [Homo sapiens] Length = 2346 Score = 33.5 bits (75), Expect = 0.17 Identities = 55/196 (28%), Positives = 87/196 (44%), Gaps = 31/196 (15%) Query: 3 LHVKTLSLMTWRSRFLEESFWSLEETAALAKQLPLKSPSENIFLHIVDLSDPKQIWKFVE 62 LHV +SL S FL SLE L P+ + L+ VD+ + K+V Sbjct: 637 LHVADVSLRNSVSNFLH----SLERGQVL--------PAHTL-LNTVDVELIYEGVKYVL 683 Query: 63 NF-KQEHKLHVLINNAGCM-VNKRELTEDGLEKNFAANTLGVYI--------LTTG-LIP 111 +Q +V+I N C+ V+ L++ GL ++ ++ Y+ +T G Sbjct: 684 KVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDGSSYTTYMKEEVDRYRITIGNKTC 743 Query: 112 VLEKEHDPRVITVSSGGMLVQKLNTNDLQSERTPFDGTMVYAQNKRQQVVLTERWAQGHP 171 V EKE+DP V+ S G L+Q + ++ F G YA+ + ++V+T A Sbjct: 744 VFEKENDPSVMRSPSAGKLIQYI----VEDGGHVFAG-QCYAEIEVMKMVMT-LTAVESG 797 Query: 172 AIHFSSMHPGWADTPG 187 IH+ PG A PG Sbjct: 798 CIHYVK-RPGAALDPG 812 >gi|38679974 acetyl-Coenzyme A carboxylase alpha isoform 4 [Homo sapiens] Length = 2268 Score = 33.5 bits (75), Expect = 0.17 Identities = 55/196 (28%), Positives = 87/196 (44%), Gaps = 31/196 (15%) Query: 3 LHVKTLSLMTWRSRFLEESFWSLEETAALAKQLPLKSPSENIFLHIVDLSDPKQIWKFVE 62 LHV +SL S FL SLE L P+ + L+ VD+ + K+V Sbjct: 559 LHVADVSLRNSVSNFLH----SLERGQVL--------PAHTL-LNTVDVELIYEGVKYVL 605 Query: 63 NF-KQEHKLHVLINNAGCM-VNKRELTEDGLEKNFAANTLGVYI--------LTTG-LIP 111 +Q +V+I N C+ V+ L++ GL ++ ++ Y+ +T G Sbjct: 606 KVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDGSSYTTYMKEEVDRYRITIGNKTC 665 Query: 112 VLEKEHDPRVITVSSGGMLVQKLNTNDLQSERTPFDGTMVYAQNKRQQVVLTERWAQGHP 171 V EKE+DP V+ S G L+Q + ++ F G YA+ + ++V+T A Sbjct: 666 VFEKENDPSVMRSPSAGKLIQYI----VEDGGHVFAG-QCYAEIEVMKMVMT-LTAVESG 719 Query: 172 AIHFSSMHPGWADTPG 187 IH+ PG A PG Sbjct: 720 CIHYVK-RPGAALDPG 734 >gi|38679971 acetyl-Coenzyme A carboxylase alpha isoform 3 [Homo sapiens] Length = 2288 Score = 33.5 bits (75), Expect = 0.17 Identities = 55/196 (28%), Positives = 87/196 (44%), Gaps = 31/196 (15%) Query: 3 LHVKTLSLMTWRSRFLEESFWSLEETAALAKQLPLKSPSENIFLHIVDLSDPKQIWKFVE 62 LHV +SL S FL SLE L P+ + L+ VD+ + K+V Sbjct: 579 LHVADVSLRNSVSNFLH----SLERGQVL--------PAHTL-LNTVDVELIYEGVKYVL 625 Query: 63 NF-KQEHKLHVLINNAGCM-VNKRELTEDGLEKNFAANTLGVYI--------LTTG-LIP 111 +Q +V+I N C+ V+ L++ GL ++ ++ Y+ +T G Sbjct: 626 KVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDGSSYTTYMKEEVDRYRITIGNKTC 685 Query: 112 VLEKEHDPRVITVSSGGMLVQKLNTNDLQSERTPFDGTMVYAQNKRQQVVLTERWAQGHP 171 V EKE+DP V+ S G L+Q + ++ F G YA+ + ++V+T A Sbjct: 686 VFEKENDPSVMRSPSAGKLIQYI----VEDGGHVFAG-QCYAEIEVMKMVMT-LTAVESG 739 Query: 172 AIHFSSMHPGWADTPG 187 IH+ PG A PG Sbjct: 740 CIHYVK-RPGAALDPG 754 >gi|38679967 acetyl-Coenzyme A carboxylase alpha isoform 2 [Homo sapiens] Length = 2346 Score = 33.5 bits (75), Expect = 0.17 Identities = 55/196 (28%), Positives = 87/196 (44%), Gaps = 31/196 (15%) Query: 3 LHVKTLSLMTWRSRFLEESFWSLEETAALAKQLPLKSPSENIFLHIVDLSDPKQIWKFVE 62 LHV +SL S FL SLE L P+ + L+ VD+ + K+V Sbjct: 637 LHVADVSLRNSVSNFLH----SLERGQVL--------PAHTL-LNTVDVELIYEGVKYVL 683 Query: 63 NF-KQEHKLHVLINNAGCM-VNKRELTEDGLEKNFAANTLGVYI--------LTTG-LIP 111 +Q +V+I N C+ V+ L++ GL ++ ++ Y+ +T G Sbjct: 684 KVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDGSSYTTYMKEEVDRYRITIGNKTC 743 Query: 112 VLEKEHDPRVITVSSGGMLVQKLNTNDLQSERTPFDGTMVYAQNKRQQVVLTERWAQGHP 171 V EKE+DP V+ S G L+Q + ++ F G YA+ + ++V+T A Sbjct: 744 VFEKENDPSVMRSPSAGKLIQYI----VEDGGHVFAG-QCYAEIEVMKMVMT-LTAVESG 797 Query: 172 AIHFSSMHPGWADTPG 187 IH+ PG A PG Sbjct: 798 CIHYVK-RPGAALDPG 812 >gi|38679960 acetyl-Coenzyme A carboxylase alpha isoform 1 [Homo sapiens] Length = 2383 Score = 33.5 bits (75), Expect = 0.17 Identities = 55/196 (28%), Positives = 87/196 (44%), Gaps = 31/196 (15%) Query: 3 LHVKTLSLMTWRSRFLEESFWSLEETAALAKQLPLKSPSENIFLHIVDLSDPKQIWKFVE 62 LHV +SL S FL SLE L P+ + L+ VD+ + K+V Sbjct: 674 LHVADVSLRNSVSNFLH----SLERGQVL--------PAHTL-LNTVDVELIYEGVKYVL 720 Query: 63 NF-KQEHKLHVLINNAGCM-VNKRELTEDGLEKNFAANTLGVYI--------LTTG-LIP 111 +Q +V+I N C+ V+ L++ GL ++ ++ Y+ +T G Sbjct: 721 KVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDGSSYTTYMKEEVDRYRITIGNKTC 780 Query: 112 VLEKEHDPRVITVSSGGMLVQKLNTNDLQSERTPFDGTMVYAQNKRQQVVLTERWAQGHP 171 V EKE+DP V+ S G L+Q + ++ F G YA+ + ++V+T A Sbjct: 781 VFEKENDPSVMRSPSAGKLIQYI----VEDGGHVFAG-QCYAEIEVMKMVMT-LTAVESG 834 Query: 172 AIHFSSMHPGWADTPG 187 IH+ PG A PG Sbjct: 835 CIHYVK-RPGAALDPG 849 >gi|7705421 hydroxysteroid (17-beta) dehydrogenase 7 [Homo sapiens] Length = 341 Score = 32.7 bits (73), Expect = 0.29 Identities = 20/75 (26%), Positives = 34/75 (45%), Gaps = 1/75 (1%) Query: 70 LHVLINNAGCMVNKRELTEDGLEKNFAANTLGVYILTTGLIPVLEKEHDP-RVITVSSGG 128 +H+ G + ++T DGL++ F N G +IL L P+L +P ++I SS Sbjct: 114 IHMFSTAEGLLTQGDKITADGLQEVFETNVFGHFILIRELEPLLCHSDNPSQLIWTSSRS 173 Query: 129 MLVQKLNTNDLQSER 143 + D Q + Sbjct: 174 ARKSNFSLEDFQHSK 188 >gi|22507405 short chain dehydrogenase/reductase family 9C, member 7 [Homo sapiens] Length = 313 Score = 30.4 bits (67), Expect = 1.4 Identities = 23/90 (25%), Positives = 42/90 (46%), Gaps = 4/90 (4%) Query: 42 ENIFLHIVDLSDPKQIWKFVENFKQEHKLHVLINNAGCMVNKRE---LTEDGLEKNFAAN 98 + L + K ++V + E L L+NNAG + LT+D K N Sbjct: 74 QTTLLDVTKSESIKAAAQWVRDKVGEQGLWALVNNAGVGLPSGPNEWLTKDDFVKVINVN 133 Query: 99 TLGVYILTTGLIPVLEKEHDPRVITVSSGG 128 +G+ +T ++P++++ RV+ +SS G Sbjct: 134 LVGLIEVTLHMLPMVKRARG-RVVNMSSSG 162 >gi|119392083 hydroxysteroid (11-beta) dehydrogenase 2 [Homo sapiens] Length = 405 Score = 30.0 bits (66), Expect = 1.9 Identities = 36/112 (32%), Positives = 51/112 (45%), Gaps = 18/112 (16%) Query: 31 LAKQLPLKSP---------SENIFLHIVDLSDPKQIWKFVENFKQEHK----LHVLINNA 77 LA L L SP S + L +DL+ P I + +E F + H L L+NNA Sbjct: 110 LATVLELNSPGAIELRTCCSPRLRLLQMDLTKPGDISRVLE-FTKAHTTSTGLWGLVNNA 168 Query: 78 GC--MVNKRELTEDGLEKN-FAANTLGVYILTTGLIPVLEKEHDPRVITVSS 126 G +V EL+ ++ N G LT GL+P+L R++TV S Sbjct: 169 GHNEVVADAELSPVATFRSCMEVNFFGALELTKGLLPLLRSSRG-RIVTVGS 219 >gi|226371731 hydroxysteroid dehydrogenase like 1 isoform a [Homo sapiens] Length = 330 Score = 29.6 bits (65), Expect = 2.5 Identities = 21/88 (23%), Positives = 43/88 (48%), Gaps = 12/88 (13%) Query: 48 IVDLSDPKQIWKFVENFKQEHKLHVLINNAGCMVNK----RELTEDGL----EKNFAANT 99 + D S ++I+ + ++ + +L+NN G +L+ED L N AA + Sbjct: 123 VADFSSGREIYLPIREALKDKDVGILVNNVGVFYPYPQYFTQLSEDKLWDIINVNIAAAS 182 Query: 100 LGVYILTTGLIPVLEKEHDPRVITVSSG 127 L V+++ G++ + ++T+SSG Sbjct: 183 LMVHVVLPGMV----ERKKGAIVTISSG 206 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.319 0.133 0.406 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 9,625,022 Number of Sequences: 37866 Number of extensions: 416766 Number of successful extensions: 926 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 16 Number of HSP's successfully gapped in prelim test: 20 Number of HSP's that attempted gapping in prelim test: 901 Number of HSP's gapped (non-prelim): 40 length of query: 242 length of database: 18,247,518 effective HSP length: 99 effective length of query: 143 effective length of database: 14,498,784 effective search space: 2073326112 effective search space used: 2073326112 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.