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Search of human proteins with 13346498
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13346498 WW domain containing transcription regulator 1
[Homo sapiens]
(400 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13346498 WW domain containing transcription regulator 1 [Homo... 823 0.0
gi|5174751 Yes-associated protein 1, 65kDa isoform 2 [Homo sapiens] 343 1e-94
gi|194306653 Yes-associated protein 1, 65kDa isoform 1 [Homo sap... 333 2e-91
gi|218505835 membrane-associated guanylate kinase-related 3 iso... 54 3e-07
gi|155969695 membrane-associated guanylate kinase-related 3 iso... 54 3e-07
gi|21361472 neural precursor cell expressed, developmentally dow... 52 9e-07
gi|222352094 neural precursor cell expressed, developmentally do... 52 9e-07
gi|222352092 neural precursor cell expressed, developmentally do... 52 9e-07
gi|222352090 neural precursor cell expressed, developmentally do... 52 9e-07
gi|66346708 membrane associated guanylate kinase, WW and PDZ dom... 50 5e-06
gi|74272284 membrane associated guanylate kinase, WW and PDZ dom... 50 5e-06
gi|74272282 membrane associated guanylate kinase, WW and PDZ dom... 50 5e-06
gi|33286444 mastermind-like 2 [Homo sapiens] 49 6e-06
gi|40806211 WW domain containing E3 ubiquitin protein ligase 2 i... 48 2e-05
gi|40806207 WW domain containing E3 ubiquitin protein ligase 2 i... 48 2e-05
gi|27477109 itchy homolog E3 ubiquitin protein ligase [Homo sapi... 48 2e-05
gi|222352183 neural precursor cell expressed, developmentally do... 47 2e-05
gi|222352088 neural precursor cell expressed, developmentally do... 47 2e-05
gi|222352086 neural precursor cell expressed, developmentally do... 47 2e-05
gi|222352084 neural precursor cell expressed, developmentally do... 47 2e-05
gi|222352082 neural precursor cell expressed, developmentally do... 47 2e-05
gi|114520609 neural precursor cell expressed, developmentally do... 47 3e-05
gi|114520607 neural precursor cell expressed, developmentally do... 47 3e-05
gi|31317290 Smad ubiquitination regulatory factor 1 isoform 2 [H... 47 4e-05
gi|12232397 SMAD specific E3 ubiquitin protein ligase 2 [Homo sa... 47 4e-05
gi|13654239 WW domain containing E3 ubiquitin protein ligase 1 [... 47 4e-05
gi|27436957 membrane associated guanylate kinase, WW and PDZ dom... 46 5e-05
gi|31317292 Smad ubiquitination regulatory factor 1 isoform 1 [H... 46 7e-05
gi|29789058 WW and C2 domain containing 1 isoform 3 [Homo sapiens] 45 1e-04
gi|242247257 WW and C2 domain containing 1 isoform 2 [Homo sapiens] 45 1e-04
>gi|13346498 WW domain containing transcription regulator 1 [Homo
sapiens]
Length = 400
Score = 823 bits (2127), Expect = 0.0
Identities = 400/400 (100%), Positives = 400/400 (100%)
Query: 1 MNPASAPPPLPPPGQQVIHVTQDLDTDLEALFNSVMNPKPSSWRKKILPESFFKEPDSGS 60
MNPASAPPPLPPPGQQVIHVTQDLDTDLEALFNSVMNPKPSSWRKKILPESFFKEPDSGS
Sbjct: 1 MNPASAPPPLPPPGQQVIHVTQDLDTDLEALFNSVMNPKPSSWRKKILPESFFKEPDSGS 60
Query: 61 HSRQSSTDSSGGHPGPRLAGGAQHVRSHSSPASLQLGTGAGAAGSPAQQHAHLRQQSYDV 120
HSRQSSTDSSGGHPGPRLAGGAQHVRSHSSPASLQLGTGAGAAGSPAQQHAHLRQQSYDV
Sbjct: 61 HSRQSSTDSSGGHPGPRLAGGAQHVRSHSSPASLQLGTGAGAAGSPAQQHAHLRQQSYDV 120
Query: 121 TDELPLPPGWEMTFTATGQRYFLNHIEKITTWQDPRKAMNQPLNHMNLHPAVSSTPVPQR 180
TDELPLPPGWEMTFTATGQRYFLNHIEKITTWQDPRKAMNQPLNHMNLHPAVSSTPVPQR
Sbjct: 121 TDELPLPPGWEMTFTATGQRYFLNHIEKITTWQDPRKAMNQPLNHMNLHPAVSSTPVPQR 180
Query: 181 SMAVSQPNLVMNHQHQQQMAPSTLSQQNHPTQNPPAGLMSMPNALTTQQQQQQKLRLQRI 240
SMAVSQPNLVMNHQHQQQMAPSTLSQQNHPTQNPPAGLMSMPNALTTQQQQQQKLRLQRI
Sbjct: 181 SMAVSQPNLVMNHQHQQQMAPSTLSQQNHPTQNPPAGLMSMPNALTTQQQQQQKLRLQRI 240
Query: 241 QMERERIRMRQEELMRQEAALCRQLPMEAETLAPVQAAVNPPTMTPDMRSITNNSSDPFL 300
QMERERIRMRQEELMRQEAALCRQLPMEAETLAPVQAAVNPPTMTPDMRSITNNSSDPFL
Sbjct: 241 QMERERIRMRQEELMRQEAALCRQLPMEAETLAPVQAAVNPPTMTPDMRSITNNSSDPFL 300
Query: 301 NGGPYHSREQSTDSGLGLGCYSVPTTPEDFLSNVDEMDTGENAGQTPMNINPQQTRFPDF 360
NGGPYHSREQSTDSGLGLGCYSVPTTPEDFLSNVDEMDTGENAGQTPMNINPQQTRFPDF
Sbjct: 301 NGGPYHSREQSTDSGLGLGCYSVPTTPEDFLSNVDEMDTGENAGQTPMNINPQQTRFPDF 360
Query: 361 LDCLPGTNVDLGTLESEDLIPLFNDVESALNKSEPFLTWL 400
LDCLPGTNVDLGTLESEDLIPLFNDVESALNKSEPFLTWL
Sbjct: 361 LDCLPGTNVDLGTLESEDLIPLFNDVESALNKSEPFLTWL 400
>gi|5174751 Yes-associated protein 1, 65kDa isoform 2 [Homo sapiens]
Length = 454
Score = 343 bits (881), Expect = 1e-94
Identities = 212/436 (48%), Positives = 275/436 (63%), Gaps = 65/436 (14%)
Query: 6 APPPLPPPGQQVIHVTQDLDTDLEALFNSVMNPKPSS------WRKKILPESFFKEPDSG 59
A P PP G Q++HV D +TDLEALFN+VMNPK ++ R + LP+SFFK P+
Sbjct: 43 AAPQAPPAGHQIVHVRGDSETDLEALFNAVMNPKTANVPQTVPMRLRKLPDSFFKPPEPK 102
Query: 60 SHSRQSSTDSSGGHPGPRLAGGAQHVRSHSSPASLQLG---------TG--AGAAGSPAQ 108
SHSRQ+STD+ G A QHVR+HSSPASLQLG TG +G A +P
Sbjct: 103 SHSRQASTDA-----GTAGALTPQHVRAHSSPASLQLGAVSPGTLTPTGVVSGPAATPTA 157
Query: 109 QHAHLRQQSYDVTDELPLPPGWEMTFTATGQRYFLNHIEKITTWQDPRKAMNQPLNHMNL 168
QH LRQ S+++ D++PLP GWEM T++GQRYFLNHI++ TTWQDPRKAM L+ MN+
Sbjct: 158 QH--LRQSSFEIPDDVPLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPRKAM---LSQMNV 212
Query: 169 HPAVSSTPVPQRSMAVSQPNLVMNHQHQQQMAPSTLSQQNHPTQNPPAGLMSMPNALTTQ 228
A +S PV Q M + MN Q Q AP P Q+P G+M N+
Sbjct: 213 -TAPTSPPVQQNMMNSAS---AMN-QRISQSAPVKQPPPLAP-QSPQGGVMGGSNS---- 262
Query: 229 QQQQQKLRLQRIQMERERIRMRQEELMRQ----EAALCRQLPMEAETLAPVQAAVNPPTM 284
QQQ++RLQ++QME+ER+R++Q+EL+RQ E AL QLP E Q V+ P M
Sbjct: 263 -NQQQQMRLQQLQMEKERLRLKQQELLRQVRPQELALRSQLPT-LEQDGGTQNPVSSPGM 320
Query: 285 TPDMRSITNNSSDPFLNGGPYHSREQSTDSGLGLGCYSVPTTPEDFLSNVDEMDTGENAG 344
+ ++R++T NSSDPFLN G YHSR++STDSGL + YSVP TP+DFL++VDEMDTG+
Sbjct: 321 SQELRTMTTNSSDPFLNSGTYHSRDESTDSGLSMSSYSVPRTPDDFLNSVDEMDTGDTIN 380
Query: 345 QTPMNINPQQTRFPDFLDCLPGTNVDLGTL-------ESEDLIP---------LFNDVES 388
Q+ + QQ RFPD+L+ +PGTNVDLGTL E E+L+P + ND+ES
Sbjct: 381 QS--TLPSQQNRFPDYLEAIPGTNVDLGTLEGDGMNIEGEELMPSLQEALSSDILNDMES 438
Query: 389 ALNKS----EPFLTWL 400
L + E FLTWL
Sbjct: 439 VLAATKLDKESFLTWL 454
>gi|194306653 Yes-associated protein 1, 65kDa isoform 1 [Homo
sapiens]
Length = 504
Score = 333 bits (853), Expect = 2e-91
Identities = 213/481 (44%), Positives = 286/481 (59%), Gaps = 105/481 (21%)
Query: 6 APPPLPPPGQQVIHVTQDLDTDLEALFNSVMNPKPSS------WRKKILPESFFKEPDSG 59
A P PP G Q++HV D +TDLEALFN+VMNPK ++ R + LP+SFFK P+
Sbjct: 43 AAPQAPPAGHQIVHVRGDSETDLEALFNAVMNPKTANVPQTVPMRLRKLPDSFFKPPEPK 102
Query: 60 SHSRQSSTDSSGGHPGPRLAGGAQHVRSHSSPASLQLG---------TG--AGAAGSPAQ 108
SHSRQ+STD+ G A QHVR+HSSPASLQLG TG +G A +P
Sbjct: 103 SHSRQASTDA-----GTAGALTPQHVRAHSSPASLQLGAVSPGTLTPTGVVSGPAATPTA 157
Query: 109 QHAHLRQQSYDVTDELPLPPGWEMTFTATGQRYFLNHIEKITTWQDPRKAMNQPLNHMNL 168
QH LRQ S+++ D++PLP GWEM T++GQRYFLNHI++ TTWQDPRKAM L+ MN+
Sbjct: 158 QH--LRQSSFEIPDDVPLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPRKAM---LSQMNV 212
Query: 169 HPAVSSTPVPQRSM-------------AVSQPNLV--MNHQHQ----------------Q 197
A +S PV Q M A++Q + +NH+++ Q
Sbjct: 213 -TAPTSPPVQQNMMNSASGPLPDGWEQAMTQDGEIYYINHKNKTTSWLDPRLDPRFAMNQ 271
Query: 198 QMAPSTLSQQNHPT--QNPPAGLMSMPNALTTQQQQQQKLRLQRIQMERERIRMRQEELM 255
+++ S +Q P Q+P G+M N+ QQQ++RLQ++QME+ER+R++Q+EL+
Sbjct: 272 RISQSAPVKQPPPLAPQSPQGGVMGGSNS-----NQQQQMRLQQLQMEKERLRLKQQELL 326
Query: 256 RQ----------------EAALCRQLPMEAETLAPVQAAVNPPTMTPDMRSITNNSSDPF 299
RQ E AL QLP E Q V+ P M+ ++R++T NSSDPF
Sbjct: 327 RQAMRNINPSTANSPKCQELALRSQLPT-LEQDGGTQNPVSSPGMSQELRTMTTNSSDPF 385
Query: 300 LNGGPYHSREQSTDSGLGLGCYSVPTTPEDFLSNVDEMDTGENAGQTPMNINPQQTRFPD 359
LN G YHSR++STDSGL + YSVP TP+DFL++VDEMDTG+ Q+ + QQ RFPD
Sbjct: 386 LNSGTYHSRDESTDSGLSMSSYSVPRTPDDFLNSVDEMDTGDTINQS--TLPSQQNRFPD 443
Query: 360 FLDCLPGTNVDLGTL-------ESEDLIP---------LFNDVESALNKS----EPFLTW 399
+L+ +PGTNVDLGTL E E+L+P + ND+ES L + E FLTW
Sbjct: 444 YLEAIPGTNVDLGTLEGDGMNIEGEELMPSLQEALSSDILNDMESVLAATKLDKESFLTW 503
Query: 400 L 400
L
Sbjct: 504 L 504
>gi|218505835 membrane-associated guanylate kinase-related 3
isoform 1 [Homo sapiens]
Length = 1481
Score = 53.5 bits (127), Expect = 3e-07
Identities = 44/156 (28%), Positives = 64/156 (41%), Gaps = 26/156 (16%)
Query: 3 PASAPPPLPPPGQQVIHVTQDLDTDLEALFNSVMNPKPSSWRKKILPESFFKEPDSGSHS 62
PA P P P QV+ D + +A S RK+ S + DS
Sbjct: 194 PAEPSPFQPDPVDQVL-----FDNEFDA----------ESQRKRTTSVSKMERMDSSLPE 238
Query: 63 RQSSTDSSGGHPGPRLAGGAQHVRSHSSPASLQLGTGAGAAGSPAQQHAHLRQQSYDVTD 122
+ D + +G A++ HS + S Q ++ + ++Y + D
Sbjct: 239 EEEDEDKEAING----SGNAENRERHSESSDWMK-----TVPSYNQTNSSMDFRNYMMRD 289
Query: 123 EL--PLPPGWEMTFTATGQRYFLNHIEKITTWQDPR 156
E PLP WEM +T TG YF++H K TTW DPR
Sbjct: 290 ETLEPLPKNWEMAYTDTGMIYFIDHNTKTTTWLDPR 325
>gi|155969695 membrane-associated guanylate kinase-related 3
isoform 2 [Homo sapiens]
Length = 1125
Score = 53.5 bits (127), Expect = 3e-07
Identities = 44/156 (28%), Positives = 64/156 (41%), Gaps = 26/156 (16%)
Query: 3 PASAPPPLPPPGQQVIHVTQDLDTDLEALFNSVMNPKPSSWRKKILPESFFKEPDSGSHS 62
PA P P P QV+ D + +A S RK+ S + DS
Sbjct: 194 PAEPSPFQPDPVDQVL-----FDNEFDA----------ESQRKRTTSVSKMERMDSSLPE 238
Query: 63 RQSSTDSSGGHPGPRLAGGAQHVRSHSSPASLQLGTGAGAAGSPAQQHAHLRQQSYDVTD 122
+ D + +G A++ HS + S Q ++ + ++Y + D
Sbjct: 239 EEEDEDKEAING----SGNAENRERHSESSDWMK-----TVPSYNQTNSSMDFRNYMMRD 289
Query: 123 EL--PLPPGWEMTFTATGQRYFLNHIEKITTWQDPR 156
E PLP WEM +T TG YF++H K TTW DPR
Sbjct: 290 ETLEPLPKNWEMAYTDTGMIYFIDHNTKTTTWLDPR 325
>gi|21361472 neural precursor cell expressed, developmentally
down-regulated 4-like isoform 3 [Homo sapiens]
Length = 955
Score = 52.0 bits (123), Expect = 9e-07
Identities = 39/158 (24%), Positives = 63/158 (39%), Gaps = 12/158 (7%)
Query: 10 LPPPGQQVIHVTQDLDTDLEALFNSV-------MNPKPSSWRKKILPESFFKEPDSGSHS 62
LPPP +H T L + E ++ N + ++W + I+ + S ++S
Sbjct: 353 LPPPSVAYVHTTPGLPSGWEERKDAKGRTYYVNHNNRTTTWTRPIMQLAEDGASGSATNS 412
Query: 63 RQSSTDSSGGHP----GPRLAGGAQHVRSHSSPASLQLGTGAGAAGSPAQQHAHLRQQSY 118
+ P P + A + SP + SP + + +
Sbjct: 413 NNHLIEPQIRRPRSLSSPTVTLSAPLEGAKDSPVRRAVKDTLSNPQSPQPSPYNSPKPQH 472
Query: 119 DVTDELPLPPGWEMTFTATGQRYFLNHIEKITTWQDPR 156
VT LPPGWEM G+ +F++H K TTW+DPR
Sbjct: 473 KVTQSF-LPPGWEMRIAPNGRPFFIDHNTKTTTWEDPR 509
Score = 47.0 bits (110), Expect = 3e-05
Identities = 24/68 (35%), Positives = 36/68 (52%), Gaps = 11/68 (16%)
Query: 112 HLRQQ-SYDVTDELPLPPGWEMTFTATGQRYFLNHIEKITTWQDPRKAMNQPLNHMNLHP 170
H+R + S + D PLPPGWE G+ ++++H KIT W+DPR +P
Sbjct: 515 HMRSKTSLNPNDLGPLPPGWEERIHLDGRTFYIDHNSKITQWEDPRLQ----------NP 564
Query: 171 AVSSTPVP 178
A++ VP
Sbjct: 565 AITGPAVP 572
Score = 38.5 bits (88), Expect = 0.011
Identities = 14/31 (45%), Positives = 18/31 (58%)
Query: 125 PLPPGWEMTFTATGQRYFLNHIEKITTWQDP 155
PLPPGWE G+ Y++NH + T W P
Sbjct: 194 PLPPGWEEKVDNLGRTYYVNHNNRTTQWHRP 224
>gi|222352094 neural precursor cell expressed, developmentally
down-regulated 4-like isoform 6 [Homo sapiens]
Length = 834
Score = 52.0 bits (123), Expect = 9e-07
Identities = 39/158 (24%), Positives = 63/158 (39%), Gaps = 12/158 (7%)
Query: 10 LPPPGQQVIHVTQDLDTDLEALFNSV-------MNPKPSSWRKKILPESFFKEPDSGSHS 62
LPPP +H T L + E ++ N + ++W + I+ + S ++S
Sbjct: 232 LPPPSVAYVHTTPGLPSGWEERKDAKGRTYYVNHNNRTTTWTRPIMQLAEDGASGSATNS 291
Query: 63 RQSSTDSSGGHP----GPRLAGGAQHVRSHSSPASLQLGTGAGAAGSPAQQHAHLRQQSY 118
+ P P + A + SP + SP + + +
Sbjct: 292 NNHLIEPQIRRPRSLSSPTVTLSAPLEGAKDSPVRRAVKDTLSNPQSPQPSPYNSPKPQH 351
Query: 119 DVTDELPLPPGWEMTFTATGQRYFLNHIEKITTWQDPR 156
VT LPPGWEM G+ +F++H K TTW+DPR
Sbjct: 352 KVTQSF-LPPGWEMRIAPNGRPFFIDHNTKTTTWEDPR 388
Score = 47.0 bits (110), Expect = 3e-05
Identities = 24/68 (35%), Positives = 36/68 (52%), Gaps = 11/68 (16%)
Query: 112 HLRQQ-SYDVTDELPLPPGWEMTFTATGQRYFLNHIEKITTWQDPRKAMNQPLNHMNLHP 170
H+R + S + D PLPPGWE G+ ++++H KIT W+DPR +P
Sbjct: 394 HMRSKTSLNPNDLGPLPPGWEERIHLDGRTFYIDHNSKITQWEDPRLQ----------NP 443
Query: 171 AVSSTPVP 178
A++ VP
Sbjct: 444 AITGPAVP 451
Score = 38.5 bits (88), Expect = 0.011
Identities = 14/31 (45%), Positives = 18/31 (58%)
Query: 125 PLPPGWEMTFTATGQRYFLNHIEKITTWQDP 155
PLPPGWE G+ Y++NH + T W P
Sbjct: 73 PLPPGWEEKVDNLGRTYYVNHNNRTTQWHRP 103
>gi|222352092 neural precursor cell expressed, developmentally
down-regulated 4-like isoform 6 [Homo sapiens]
Length = 834
Score = 52.0 bits (123), Expect = 9e-07
Identities = 39/158 (24%), Positives = 63/158 (39%), Gaps = 12/158 (7%)
Query: 10 LPPPGQQVIHVTQDLDTDLEALFNSV-------MNPKPSSWRKKILPESFFKEPDSGSHS 62
LPPP +H T L + E ++ N + ++W + I+ + S ++S
Sbjct: 232 LPPPSVAYVHTTPGLPSGWEERKDAKGRTYYVNHNNRTTTWTRPIMQLAEDGASGSATNS 291
Query: 63 RQSSTDSSGGHP----GPRLAGGAQHVRSHSSPASLQLGTGAGAAGSPAQQHAHLRQQSY 118
+ P P + A + SP + SP + + +
Sbjct: 292 NNHLIEPQIRRPRSLSSPTVTLSAPLEGAKDSPVRRAVKDTLSNPQSPQPSPYNSPKPQH 351
Query: 119 DVTDELPLPPGWEMTFTATGQRYFLNHIEKITTWQDPR 156
VT LPPGWEM G+ +F++H K TTW+DPR
Sbjct: 352 KVTQSF-LPPGWEMRIAPNGRPFFIDHNTKTTTWEDPR 388
Score = 47.0 bits (110), Expect = 3e-05
Identities = 24/68 (35%), Positives = 36/68 (52%), Gaps = 11/68 (16%)
Query: 112 HLRQQ-SYDVTDELPLPPGWEMTFTATGQRYFLNHIEKITTWQDPRKAMNQPLNHMNLHP 170
H+R + S + D PLPPGWE G+ ++++H KIT W+DPR +P
Sbjct: 394 HMRSKTSLNPNDLGPLPPGWEERIHLDGRTFYIDHNSKITQWEDPRLQ----------NP 443
Query: 171 AVSSTPVP 178
A++ VP
Sbjct: 444 AITGPAVP 451
Score = 38.5 bits (88), Expect = 0.011
Identities = 14/31 (45%), Positives = 18/31 (58%)
Query: 125 PLPPGWEMTFTATGQRYFLNHIEKITTWQDP 155
PLPPGWE G+ Y++NH + T W P
Sbjct: 73 PLPPGWEEKVDNLGRTYYVNHNNRTTQWHRP 103
>gi|222352090 neural precursor cell expressed, developmentally
down-regulated 4-like isoform 5 [Homo sapiens]
Length = 947
Score = 52.0 bits (123), Expect = 9e-07
Identities = 39/158 (24%), Positives = 63/158 (39%), Gaps = 12/158 (7%)
Query: 10 LPPPGQQVIHVTQDLDTDLEALFNSV-------MNPKPSSWRKKILPESFFKEPDSGSHS 62
LPPP +H T L + E ++ N + ++W + I+ + S ++S
Sbjct: 345 LPPPSVAYVHTTPGLPSGWEERKDAKGRTYYVNHNNRTTTWTRPIMQLAEDGASGSATNS 404
Query: 63 RQSSTDSSGGHP----GPRLAGGAQHVRSHSSPASLQLGTGAGAAGSPAQQHAHLRQQSY 118
+ P P + A + SP + SP + + +
Sbjct: 405 NNHLIEPQIRRPRSLSSPTVTLSAPLEGAKDSPVRRAVKDTLSNPQSPQPSPYNSPKPQH 464
Query: 119 DVTDELPLPPGWEMTFTATGQRYFLNHIEKITTWQDPR 156
VT LPPGWEM G+ +F++H K TTW+DPR
Sbjct: 465 KVTQSF-LPPGWEMRIAPNGRPFFIDHNTKTTTWEDPR 501
Score = 47.0 bits (110), Expect = 3e-05
Identities = 24/68 (35%), Positives = 36/68 (52%), Gaps = 11/68 (16%)
Query: 112 HLRQQ-SYDVTDELPLPPGWEMTFTATGQRYFLNHIEKITTWQDPRKAMNQPLNHMNLHP 170
H+R + S + D PLPPGWE G+ ++++H KIT W+DPR +P
Sbjct: 507 HMRSKTSLNPNDLGPLPPGWEERIHLDGRTFYIDHNSKITQWEDPRLQ----------NP 556
Query: 171 AVSSTPVP 178
A++ VP
Sbjct: 557 AITGPAVP 564
Score = 38.5 bits (88), Expect = 0.011
Identities = 14/31 (45%), Positives = 18/31 (58%)
Query: 125 PLPPGWEMTFTATGQRYFLNHIEKITTWQDP 155
PLPPGWE G+ Y++NH + T W P
Sbjct: 186 PLPPGWEEKVDNLGRTYYVNHNNRTTQWHRP 216
>gi|66346708 membrane associated guanylate kinase, WW and PDZ domain
containing 1 isoform b [Homo sapiens]
Length = 1256
Score = 49.7 bits (117), Expect = 5e-06
Identities = 54/215 (25%), Positives = 83/215 (38%), Gaps = 27/215 (12%)
Query: 125 PLPPGWEMTFTATGQRYFLNHIEKITTWQDPR--KAMNQPLNHMNLHPAV------SSTP 176
PLP WEM +T G+ YF++H K T+W DPR +PL V S
Sbjct: 301 PLPENWEMAYTENGEVYFIDHNTKTTSWLDPRCLNKQQKPLEECEDDEGVHTEELDSELE 360
Query: 177 VPQRSMAVSQPNLVMNHQHQQQMAPSTLSQQNHPTQNPPAGLMSMPNALTTQQQQQQKLR 236
+P + P + + + N TQ L + QQQQQQ+
Sbjct: 361 LPAGWEKIEDPVYGIYY----------VDHINRKTQYENPVLEAKRKKQLEQQQQQQQ-- 408
Query: 237 LQRIQMERERIRMRQEELMRQEAALCRQLPMEAETLAPVQAAVNPPTMTPDMRSITNNSS 296
Q+ Q ++++ + + EE +AL + P A P P T N S
Sbjct: 409 -QQQQQQQQQQQQQTEEWTEDHSALVPPVIPNHPPSNPEPAREVPLQGKP---FFTRNPS 464
Query: 297 DPFLNGGPYHSREQSTDSGLGLGCYSVPTTPEDFL 331
+ L G H++ + + G G P++FL
Sbjct: 465 E--LKGKFIHTKLRKSSRGFGFTVVG-GDEPDEFL 496
Score = 32.3 bits (72), Expect = 0.78
Identities = 25/104 (24%), Positives = 37/104 (35%), Gaps = 20/104 (19%)
Query: 119 DVTDELPLPPGWEMTFTATGQRYFLNHIEKITTWQDPRKAMNQPLNHMNLHPAVSSTPVP 178
++ EL LP GWE Y+++HI + T +++P + A +
Sbjct: 354 ELDSELELPAGWEKIEDPVYGIYYVDHINRKTQYENP------------VLEAKRKKQLE 401
Query: 179 QRSMAVSQPNLVMNHQHQQQMAPSTLSQQ--------NHPTQNP 214
Q+ Q Q QQQ T NHP NP
Sbjct: 402 QQQQQQQQQQQQQQQQQQQQTEEWTEDHSALVPPVIPNHPPSNP 445
>gi|74272284 membrane associated guanylate kinase, WW and PDZ domain
containing 1 isoform c [Homo sapiens]
Length = 1462
Score = 49.7 bits (117), Expect = 5e-06
Identities = 54/215 (25%), Positives = 83/215 (38%), Gaps = 27/215 (12%)
Query: 125 PLPPGWEMTFTATGQRYFLNHIEKITTWQDPR--KAMNQPLNHMNLHPAV------SSTP 176
PLP WEM +T G+ YF++H K T+W DPR +PL V S
Sbjct: 301 PLPENWEMAYTENGEVYFIDHNTKTTSWLDPRCLNKQQKPLEECEDDEGVHTEELDSELE 360
Query: 177 VPQRSMAVSQPNLVMNHQHQQQMAPSTLSQQNHPTQNPPAGLMSMPNALTTQQQQQQKLR 236
+P + P + + + N TQ L + QQQQQQ+
Sbjct: 361 LPAGWEKIEDPVYGIYY----------VDHINRKTQYENPVLEAKRKKQLEQQQQQQQ-- 408
Query: 237 LQRIQMERERIRMRQEELMRQEAALCRQLPMEAETLAPVQAAVNPPTMTPDMRSITNNSS 296
Q+ Q ++++ + + EE +AL + P A P P T N S
Sbjct: 409 -QQQQQQQQQQQQQTEEWTEDHSALVPPVIPNHPPSNPEPAREVPLQGKP---FFTRNPS 464
Query: 297 DPFLNGGPYHSREQSTDSGLGLGCYSVPTTPEDFL 331
+ L G H++ + + G G P++FL
Sbjct: 465 E--LKGKFIHTKLRKSSRGFGFTVVG-GDEPDEFL 496
Score = 32.3 bits (72), Expect = 0.78
Identities = 25/104 (24%), Positives = 37/104 (35%), Gaps = 20/104 (19%)
Query: 119 DVTDELPLPPGWEMTFTATGQRYFLNHIEKITTWQDPRKAMNQPLNHMNLHPAVSSTPVP 178
++ EL LP GWE Y+++HI + T +++P + A +
Sbjct: 354 ELDSELELPAGWEKIEDPVYGIYYVDHINRKTQYENP------------VLEAKRKKQLE 401
Query: 179 QRSMAVSQPNLVMNHQHQQQMAPSTLSQQ--------NHPTQNP 214
Q+ Q Q QQQ T NHP NP
Sbjct: 402 QQQQQQQQQQQQQQQQQQQQTEEWTEDHSALVPPVIPNHPPSNP 445
>gi|74272282 membrane associated guanylate kinase, WW and PDZ domain
containing 1 isoform a [Homo sapiens]
Length = 1287
Score = 49.7 bits (117), Expect = 5e-06
Identities = 54/215 (25%), Positives = 83/215 (38%), Gaps = 27/215 (12%)
Query: 125 PLPPGWEMTFTATGQRYFLNHIEKITTWQDPR--KAMNQPLNHMNLHPAV------SSTP 176
PLP WEM +T G+ YF++H K T+W DPR +PL V S
Sbjct: 301 PLPENWEMAYTENGEVYFIDHNTKTTSWLDPRCLNKQQKPLEECEDDEGVHTEELDSELE 360
Query: 177 VPQRSMAVSQPNLVMNHQHQQQMAPSTLSQQNHPTQNPPAGLMSMPNALTTQQQQQQKLR 236
+P + P + + + N TQ L + QQQQQQ+
Sbjct: 361 LPAGWEKIEDPVYGIYY----------VDHINRKTQYENPVLEAKRKKQLEQQQQQQQ-- 408
Query: 237 LQRIQMERERIRMRQEELMRQEAALCRQLPMEAETLAPVQAAVNPPTMTPDMRSITNNSS 296
Q+ Q ++++ + + EE +AL + P A P P T N S
Sbjct: 409 -QQQQQQQQQQQQQTEEWTEDHSALVPPVIPNHPPSNPEPAREVPLQGKP---FFTRNPS 464
Query: 297 DPFLNGGPYHSREQSTDSGLGLGCYSVPTTPEDFL 331
+ L G H++ + + G G P++FL
Sbjct: 465 E--LKGKFIHTKLRKSSRGFGFTVVG-GDEPDEFL 496
Score = 32.3 bits (72), Expect = 0.78
Identities = 25/104 (24%), Positives = 37/104 (35%), Gaps = 20/104 (19%)
Query: 119 DVTDELPLPPGWEMTFTATGQRYFLNHIEKITTWQDPRKAMNQPLNHMNLHPAVSSTPVP 178
++ EL LP GWE Y+++HI + T +++P + A +
Sbjct: 354 ELDSELELPAGWEKIEDPVYGIYYVDHINRKTQYENP------------VLEAKRKKQLE 401
Query: 179 QRSMAVSQPNLVMNHQHQQQMAPSTLSQQ--------NHPTQNP 214
Q+ Q Q QQQ T NHP NP
Sbjct: 402 QQQQQQQQQQQQQQQQQQQQTEEWTEDHSALVPPVIPNHPPSNP 445
>gi|33286444 mastermind-like 2 [Homo sapiens]
Length = 1156
Score = 49.3 bits (116), Expect = 6e-06
Identities = 72/338 (21%), Positives = 127/338 (37%), Gaps = 46/338 (13%)
Query: 19 HVTQDLDTDLEALFNSVMNPKPSSWRKKILPESFFKEPDSGSHSRQSSTDSSGGHPGPRL 78
H Q T+ AL +S P P + ++ +P F + + S QSS P P +
Sbjct: 452 HQQQHQPTNWSALPSSA-GPSPGPFGQEKIPSPSFGQQ---TFSPQSS-------PMPGV 500
Query: 79 AGGAQHVRSHSSPASLQLGTGAGAAGSPAQQHAHLRQQSYDVTDELPLPPGWEMTFTATG 138
AGG S S AG + ++Q+ D++
Sbjct: 501 AGG-----SGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLS----------------- 538
Query: 139 QRYFLNHIEKITTWQDPRKAMNQPLNHMNLHPAVSSTPVPQRSMAVSQPNLV-----MNH 193
R F+N+ +PR+ +PL H N A P S ++P+L+
Sbjct: 539 -RSFINNPHPA---MEPRQGNTKPLFHFNSDQANQQMPSVLPSQ--NKPSLLHYTQQQQQ 592
Query: 194 QHQQQMAPSTLSQQNHPTQNPPAGLMSMPNALTTQQQQQQ--KLRLQRIQMERERIRMRQ 251
Q QQQ QQ Q ++++ QQQQQQ + Q+ Q ++++ + +Q
Sbjct: 593 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQ 652
Query: 252 EELMRQEAALCRQLPMEAETLAPVQAAVNPPTMTPDMRSITNNSSDPFLNGGPYHSREQS 311
++ +Q+ +Q + P Q + P + + P G S++Q
Sbjct: 653 QQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQR 712
Query: 312 TDSGLGLGCYSVPTTPEDFLSNVDEMDTGENAGQTPMN 349
D +G + P+ + SN + N+ Q+ +N
Sbjct: 713 QDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSLLN 750
Score = 36.2 bits (82), Expect = 0.054
Identities = 43/173 (24%), Positives = 71/173 (41%), Gaps = 35/173 (20%)
Query: 153 QDPRKAMNQPLNHMNLHPAVSSTPVPQRSMAV-----SQPNLVMNHQHQQQMAP---STL 204
Q ++ +QP + P + S P+P + + +QP M +Q QQ S +
Sbjct: 661 QQQQQPSSQPAQSLPSQPLLRS-PLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVV 719
Query: 205 SQQNHPTQNPP--------AGLMSMPNALTTQQQQQQKLRLQRIQMERERIRMRQEELMR 256
Q P+ +P +G M+ +L QQ +K LQR ME+ +
Sbjct: 720 GQNTGPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMGKKQTLQRQIMEQ-----------K 768
Query: 257 QEAALCRQLPMEAETLAPVQAAVN------PPTMTPDMRSITNNSSDPFLNGG 303
Q+ L +Q+ +AE +AP Q +N PP R++ N +GG
Sbjct: 769 QQLLLQQQMLADAEKIAP-QDQINRHLSRPPPDYKDQRRNVGNMQPTAQYSGG 820
>gi|40806211 WW domain containing E3 ubiquitin protein ligase 2
isoform 2 [Homo sapiens]
Length = 431
Score = 47.8 bits (112), Expect = 2e-05
Identities = 19/34 (55%), Positives = 26/34 (76%)
Query: 123 ELPLPPGWEMTFTATGQRYFLNHIEKITTWQDPR 156
E LPPGWEM +T+ G RYF++H + TT++DPR
Sbjct: 4 EPALPPGWEMKYTSEGVRYFVDHNTRTTTFKDPR 37
>gi|40806207 WW domain containing E3 ubiquitin protein ligase 2
isoform 1 [Homo sapiens]
Length = 870
Score = 47.8 bits (112), Expect = 2e-05
Identities = 19/34 (55%), Positives = 26/34 (76%)
Query: 123 ELPLPPGWEMTFTATGQRYFLNHIEKITTWQDPR 156
E LPPGWEM +T+ G RYF++H + TT++DPR
Sbjct: 443 EPALPPGWEMKYTSEGVRYFVDHNTRTTTFKDPR 476
Score = 43.1 bits (100), Expect = 4e-04
Identities = 44/161 (27%), Positives = 66/161 (40%), Gaps = 28/161 (17%)
Query: 4 ASAPPPLPP-------PGQQVIHVTQDLDTDLEALFNSVMNPKPSSWRKKILPESFFKEP 56
A AP LP P +V +V + T + P P W K+ P F
Sbjct: 296 AQAPDALPAGWEQRELPNGRVYYVDHNTKT------TTWERPLPPGWEKRTDPRGRFYYV 349
Query: 57 DSGSHSRQSSTDSSGGHPGPRLAGGAQHVRSHSSPASLQLGTGAGAAGSPAQQHAHLRQQ 116
D H+ +++T A++VR++ S Q GA +Q+ +
Sbjct: 350 D---HNTRTTTWQRPT---------AEYVRNYEQWQS-QRNQLQGAMQHFSQRFLYQSSS 396
Query: 117 SYDVTDEL-PLPPGWEMTFTATGQRYFLNHIEKITTWQDPR 156
+ D L PLPPGWE G+ Y++NH + T W+DPR
Sbjct: 397 ASTDHDPLGPLPPGWEKR-QDNGRVYYVNHNTRTTQWEDPR 436
Score = 36.6 bits (83), Expect = 0.041
Identities = 35/129 (27%), Positives = 49/129 (37%), Gaps = 34/129 (26%)
Query: 55 EPDSGSHSRQSSTDSSGGHPGPRLAGGAQH-------------VRSHSSPASLQLG---- 97
E G+ SR + GH G LA G + V +SP + L
Sbjct: 209 EQSPGARSRHRQPVKNSGHSG--LANGTVNDEPTTATDPEEPSVVGVTSPPAAPLSVTPN 266
Query: 98 ---TGAGAAGSPAQQHAHLRQQSYDVTDELP--------LPPGWEMTFTATGQRYFLNHI 146
T A +PA+ + S T +LP LP GWE G+ Y+++H
Sbjct: 267 PNTTSLPAPATPAEGE----EPSTSGTQQLPAAAQAPDALPAGWEQRELPNGRVYYVDHN 322
Query: 147 EKITTWQDP 155
K TTW+ P
Sbjct: 323 TKTTTWERP 331
>gi|27477109 itchy homolog E3 ubiquitin protein ligase [Homo
sapiens]
Length = 862
Score = 47.8 bits (112), Expect = 2e-05
Identities = 18/32 (56%), Positives = 23/32 (71%)
Query: 125 PLPPGWEMTFTATGQRYFLNHIEKITTWQDPR 156
PLPPGWE + G+ YF+NH +IT W+DPR
Sbjct: 398 PLPPGWEKRTDSNGRVYFVNHNTRITQWEDPR 429
Score = 45.4 bits (106), Expect = 9e-05
Identities = 19/35 (54%), Positives = 24/35 (68%)
Query: 122 DELPLPPGWEMTFTATGQRYFLNHIEKITTWQDPR 156
+E PLP GWEM FT G YF++H + TT+ DPR
Sbjct: 435 NEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPR 469
Score = 43.9 bits (102), Expect = 3e-04
Identities = 16/33 (48%), Positives = 22/33 (66%)
Query: 123 ELPLPPGWEMTFTATGQRYFLNHIEKITTWQDP 155
+ PLPPGWE G+ Y+++H+EK TTW P
Sbjct: 284 QAPLPPGWEQRVDQHGRVYYVDHVEKRTTWDRP 316
Score = 41.2 bits (95), Expect = 0.002
Identities = 15/31 (48%), Positives = 20/31 (64%)
Query: 125 PLPPGWEMTFTATGQRYFLNHIEKITTWQDP 155
PLPPGWE G+ Y+++H + TTWQ P
Sbjct: 318 PLPPGWERRVDNMGRIYYVDHFTRTTTWQRP 348
>gi|222352183 neural precursor cell expressed, developmentally
down-regulated 4-like isoform 2 [Homo sapiens]
Length = 854
Score = 47.4 bits (111), Expect = 2e-05
Identities = 37/157 (23%), Positives = 61/157 (38%), Gaps = 12/157 (7%)
Query: 11 PPPGQQVIHVTQDLDTDLEALFNSV-------MNPKPSSWRKKILPESFFKEPDSGSHSR 63
P P +H T L + E ++ N + ++W + I+ + S ++S
Sbjct: 253 PTPSVAYVHTTPGLPSGWEERKDAKGRTYYVNHNNRTTTWTRPIMQLAEDGASGSATNSN 312
Query: 64 QSSTDSSGGHP----GPRLAGGAQHVRSHSSPASLQLGTGAGAAGSPAQQHAHLRQQSYD 119
+ P P + A + SP + SP + + +
Sbjct: 313 NHLIEPQIRRPRSLSSPTVTLSAPLEGAKDSPVRRAVKDTLSNPQSPQPSPYNSPKPQHK 372
Query: 120 VTDELPLPPGWEMTFTATGQRYFLNHIEKITTWQDPR 156
VT LPPGWEM G+ +F++H K TTW+DPR
Sbjct: 373 VTQSF-LPPGWEMRIAPNGRPFFIDHNTKTTTWEDPR 408
Score = 47.0 bits (110), Expect = 3e-05
Identities = 24/68 (35%), Positives = 36/68 (52%), Gaps = 11/68 (16%)
Query: 112 HLRQQ-SYDVTDELPLPPGWEMTFTATGQRYFLNHIEKITTWQDPRKAMNQPLNHMNLHP 170
H+R + S + D PLPPGWE G+ ++++H KIT W+DPR +P
Sbjct: 414 HMRSKTSLNPNDLGPLPPGWEERIHLDGRTFYIDHNSKITQWEDPRLQ----------NP 463
Query: 171 AVSSTPVP 178
A++ VP
Sbjct: 464 AITGPAVP 471
Score = 38.9 bits (89), Expect = 0.008
Identities = 43/182 (23%), Positives = 74/182 (40%), Gaps = 28/182 (15%)
Query: 125 PLPPGWEMTFTATGQRYFLNHIEKITTWQDPR------------KAMNQPLNHMNL---- 168
PLPPGWE G+ Y++NH + T W P + +NQ H
Sbjct: 73 PLPPGWEEKVDNLGRTYYVNHNNRTTQWHRPSLMDVSSESDNNIRQINQEAAHRRFRSRR 132
Query: 169 HPAVSSTPVPQRSMAVSQPNLVMNHQHQQQMAPSTLSQQNHPTQNPPAGLMSMPNALTTQ 228
H + P P V +P ++ + +A +L P PPA P + T+
Sbjct: 133 HISEDLEPEPSEGGDVPEPWETIS--EEVNIAGDSLGLALPP---PPAS----PGSRTSP 183
Query: 229 QQQQQKLRLQRIQMERERIRMRQEELMRQEAALCRQLPMEAETLAPVQAAVNPPTMTPDM 288
Q+ ++L +R+Q+ + + L+++E + +L + T A + PP P
Sbjct: 184 QELSEELS-RRLQITPDSNGEQFSSLIQREPS--SRLRSCSVTDAVAEQGHLPPPSAPAG 240
Query: 289 RS 290
R+
Sbjct: 241 RA 242
>gi|222352088 neural precursor cell expressed, developmentally
down-regulated 4-like isoform 4 [Homo sapiens]
Length = 967
Score = 47.4 bits (111), Expect = 2e-05
Identities = 37/157 (23%), Positives = 61/157 (38%), Gaps = 12/157 (7%)
Query: 11 PPPGQQVIHVTQDLDTDLEALFNSV-------MNPKPSSWRKKILPESFFKEPDSGSHSR 63
P P +H T L + E ++ N + ++W + I+ + S ++S
Sbjct: 366 PTPSVAYVHTTPGLPSGWEERKDAKGRTYYVNHNNRTTTWTRPIMQLAEDGASGSATNSN 425
Query: 64 QSSTDSSGGHP----GPRLAGGAQHVRSHSSPASLQLGTGAGAAGSPAQQHAHLRQQSYD 119
+ P P + A + SP + SP + + +
Sbjct: 426 NHLIEPQIRRPRSLSSPTVTLSAPLEGAKDSPVRRAVKDTLSNPQSPQPSPYNSPKPQHK 485
Query: 120 VTDELPLPPGWEMTFTATGQRYFLNHIEKITTWQDPR 156
VT LPPGWEM G+ +F++H K TTW+DPR
Sbjct: 486 VTQSF-LPPGWEMRIAPNGRPFFIDHNTKTTTWEDPR 521
Score = 47.0 bits (110), Expect = 3e-05
Identities = 24/68 (35%), Positives = 36/68 (52%), Gaps = 11/68 (16%)
Query: 112 HLRQQ-SYDVTDELPLPPGWEMTFTATGQRYFLNHIEKITTWQDPRKAMNQPLNHMNLHP 170
H+R + S + D PLPPGWE G+ ++++H KIT W+DPR +P
Sbjct: 527 HMRSKTSLNPNDLGPLPPGWEERIHLDGRTFYIDHNSKITQWEDPRLQ----------NP 576
Query: 171 AVSSTPVP 178
A++ VP
Sbjct: 577 AITGPAVP 584
Score = 38.9 bits (89), Expect = 0.008
Identities = 43/182 (23%), Positives = 74/182 (40%), Gaps = 28/182 (15%)
Query: 125 PLPPGWEMTFTATGQRYFLNHIEKITTWQDPR------------KAMNQPLNHMNL---- 168
PLPPGWE G+ Y++NH + T W P + +NQ H
Sbjct: 186 PLPPGWEEKVDNLGRTYYVNHNNRTTQWHRPSLMDVSSESDNNIRQINQEAAHRRFRSRR 245
Query: 169 HPAVSSTPVPQRSMAVSQPNLVMNHQHQQQMAPSTLSQQNHPTQNPPAGLMSMPNALTTQ 228
H + P P V +P ++ + +A +L P PPA P + T+
Sbjct: 246 HISEDLEPEPSEGGDVPEPWETIS--EEVNIAGDSLGLALPP---PPAS----PGSRTSP 296
Query: 229 QQQQQKLRLQRIQMERERIRMRQEELMRQEAALCRQLPMEAETLAPVQAAVNPPTMTPDM 288
Q+ ++L +R+Q+ + + L+++E + +L + T A + PP P
Sbjct: 297 QELSEELS-RRLQITPDSNGEQFSSLIQREPS--SRLRSCSVTDAVAEQGHLPPPSAPAG 353
Query: 289 RS 290
R+
Sbjct: 354 RA 355
>gi|222352086 neural precursor cell expressed, developmentally
down-regulated 4-like isoform 1 [Homo sapiens]
Length = 975
Score = 47.4 bits (111), Expect = 2e-05
Identities = 37/157 (23%), Positives = 61/157 (38%), Gaps = 12/157 (7%)
Query: 11 PPPGQQVIHVTQDLDTDLEALFNSV-------MNPKPSSWRKKILPESFFKEPDSGSHSR 63
P P +H T L + E ++ N + ++W + I+ + S ++S
Sbjct: 374 PTPSVAYVHTTPGLPSGWEERKDAKGRTYYVNHNNRTTTWTRPIMQLAEDGASGSATNSN 433
Query: 64 QSSTDSSGGHP----GPRLAGGAQHVRSHSSPASLQLGTGAGAAGSPAQQHAHLRQQSYD 119
+ P P + A + SP + SP + + +
Sbjct: 434 NHLIEPQIRRPRSLSSPTVTLSAPLEGAKDSPVRRAVKDTLSNPQSPQPSPYNSPKPQHK 493
Query: 120 VTDELPLPPGWEMTFTATGQRYFLNHIEKITTWQDPR 156
VT LPPGWEM G+ +F++H K TTW+DPR
Sbjct: 494 VTQSF-LPPGWEMRIAPNGRPFFIDHNTKTTTWEDPR 529
Score = 47.0 bits (110), Expect = 3e-05
Identities = 24/68 (35%), Positives = 36/68 (52%), Gaps = 11/68 (16%)
Query: 112 HLRQQ-SYDVTDELPLPPGWEMTFTATGQRYFLNHIEKITTWQDPRKAMNQPLNHMNLHP 170
H+R + S + D PLPPGWE G+ ++++H KIT W+DPR +P
Sbjct: 535 HMRSKTSLNPNDLGPLPPGWEERIHLDGRTFYIDHNSKITQWEDPRLQ----------NP 584
Query: 171 AVSSTPVP 178
A++ VP
Sbjct: 585 AITGPAVP 592
Score = 38.9 bits (89), Expect = 0.008
Identities = 43/182 (23%), Positives = 74/182 (40%), Gaps = 28/182 (15%)
Query: 125 PLPPGWEMTFTATGQRYFLNHIEKITTWQDPR------------KAMNQPLNHMNL---- 168
PLPPGWE G+ Y++NH + T W P + +NQ H
Sbjct: 194 PLPPGWEEKVDNLGRTYYVNHNNRTTQWHRPSLMDVSSESDNNIRQINQEAAHRRFRSRR 253
Query: 169 HPAVSSTPVPQRSMAVSQPNLVMNHQHQQQMAPSTLSQQNHPTQNPPAGLMSMPNALTTQ 228
H + P P V +P ++ + +A +L P PPA P + T+
Sbjct: 254 HISEDLEPEPSEGGDVPEPWETIS--EEVNIAGDSLGLALPP---PPAS----PGSRTSP 304
Query: 229 QQQQQKLRLQRIQMERERIRMRQEELMRQEAALCRQLPMEAETLAPVQAAVNPPTMTPDM 288
Q+ ++L +R+Q+ + + L+++E + +L + T A + PP P
Sbjct: 305 QELSEELS-RRLQITPDSNGEQFSSLIQREPS--SRLRSCSVTDAVAEQGHLPPPSAPAG 361
Query: 289 RS 290
R+
Sbjct: 362 RA 363
>gi|222352084 neural precursor cell expressed, developmentally
down-regulated 4-like isoform 2 [Homo sapiens]
Length = 854
Score = 47.4 bits (111), Expect = 2e-05
Identities = 37/157 (23%), Positives = 61/157 (38%), Gaps = 12/157 (7%)
Query: 11 PPPGQQVIHVTQDLDTDLEALFNSV-------MNPKPSSWRKKILPESFFKEPDSGSHSR 63
P P +H T L + E ++ N + ++W + I+ + S ++S
Sbjct: 253 PTPSVAYVHTTPGLPSGWEERKDAKGRTYYVNHNNRTTTWTRPIMQLAEDGASGSATNSN 312
Query: 64 QSSTDSSGGHP----GPRLAGGAQHVRSHSSPASLQLGTGAGAAGSPAQQHAHLRQQSYD 119
+ P P + A + SP + SP + + +
Sbjct: 313 NHLIEPQIRRPRSLSSPTVTLSAPLEGAKDSPVRRAVKDTLSNPQSPQPSPYNSPKPQHK 372
Query: 120 VTDELPLPPGWEMTFTATGQRYFLNHIEKITTWQDPR 156
VT LPPGWEM G+ +F++H K TTW+DPR
Sbjct: 373 VTQSF-LPPGWEMRIAPNGRPFFIDHNTKTTTWEDPR 408
Score = 47.0 bits (110), Expect = 3e-05
Identities = 24/68 (35%), Positives = 36/68 (52%), Gaps = 11/68 (16%)
Query: 112 HLRQQ-SYDVTDELPLPPGWEMTFTATGQRYFLNHIEKITTWQDPRKAMNQPLNHMNLHP 170
H+R + S + D PLPPGWE G+ ++++H KIT W+DPR +P
Sbjct: 414 HMRSKTSLNPNDLGPLPPGWEERIHLDGRTFYIDHNSKITQWEDPRLQ----------NP 463
Query: 171 AVSSTPVP 178
A++ VP
Sbjct: 464 AITGPAVP 471
Score = 38.9 bits (89), Expect = 0.008
Identities = 43/182 (23%), Positives = 74/182 (40%), Gaps = 28/182 (15%)
Query: 125 PLPPGWEMTFTATGQRYFLNHIEKITTWQDPR------------KAMNQPLNHMNL---- 168
PLPPGWE G+ Y++NH + T W P + +NQ H
Sbjct: 73 PLPPGWEEKVDNLGRTYYVNHNNRTTQWHRPSLMDVSSESDNNIRQINQEAAHRRFRSRR 132
Query: 169 HPAVSSTPVPQRSMAVSQPNLVMNHQHQQQMAPSTLSQQNHPTQNPPAGLMSMPNALTTQ 228
H + P P V +P ++ + +A +L P PPA P + T+
Sbjct: 133 HISEDLEPEPSEGGDVPEPWETIS--EEVNIAGDSLGLALPP---PPAS----PGSRTSP 183
Query: 229 QQQQQKLRLQRIQMERERIRMRQEELMRQEAALCRQLPMEAETLAPVQAAVNPPTMTPDM 288
Q+ ++L +R+Q+ + + L+++E + +L + T A + PP P
Sbjct: 184 QELSEELS-RRLQITPDSNGEQFSSLIQREPS--SRLRSCSVTDAVAEQGHLPPPSAPAG 240
Query: 289 RS 290
R+
Sbjct: 241 RA 242
>gi|222352082 neural precursor cell expressed, developmentally
down-regulated 4-like isoform 2 [Homo sapiens]
Length = 854
Score = 47.4 bits (111), Expect = 2e-05
Identities = 37/157 (23%), Positives = 61/157 (38%), Gaps = 12/157 (7%)
Query: 11 PPPGQQVIHVTQDLDTDLEALFNSV-------MNPKPSSWRKKILPESFFKEPDSGSHSR 63
P P +H T L + E ++ N + ++W + I+ + S ++S
Sbjct: 253 PTPSVAYVHTTPGLPSGWEERKDAKGRTYYVNHNNRTTTWTRPIMQLAEDGASGSATNSN 312
Query: 64 QSSTDSSGGHP----GPRLAGGAQHVRSHSSPASLQLGTGAGAAGSPAQQHAHLRQQSYD 119
+ P P + A + SP + SP + + +
Sbjct: 313 NHLIEPQIRRPRSLSSPTVTLSAPLEGAKDSPVRRAVKDTLSNPQSPQPSPYNSPKPQHK 372
Query: 120 VTDELPLPPGWEMTFTATGQRYFLNHIEKITTWQDPR 156
VT LPPGWEM G+ +F++H K TTW+DPR
Sbjct: 373 VTQSF-LPPGWEMRIAPNGRPFFIDHNTKTTTWEDPR 408
Score = 47.0 bits (110), Expect = 3e-05
Identities = 24/68 (35%), Positives = 36/68 (52%), Gaps = 11/68 (16%)
Query: 112 HLRQQ-SYDVTDELPLPPGWEMTFTATGQRYFLNHIEKITTWQDPRKAMNQPLNHMNLHP 170
H+R + S + D PLPPGWE G+ ++++H KIT W+DPR +P
Sbjct: 414 HMRSKTSLNPNDLGPLPPGWEERIHLDGRTFYIDHNSKITQWEDPRLQ----------NP 463
Query: 171 AVSSTPVP 178
A++ VP
Sbjct: 464 AITGPAVP 471
Score = 38.9 bits (89), Expect = 0.008
Identities = 43/182 (23%), Positives = 74/182 (40%), Gaps = 28/182 (15%)
Query: 125 PLPPGWEMTFTATGQRYFLNHIEKITTWQDPR------------KAMNQPLNHMNL---- 168
PLPPGWE G+ Y++NH + T W P + +NQ H
Sbjct: 73 PLPPGWEEKVDNLGRTYYVNHNNRTTQWHRPSLMDVSSESDNNIRQINQEAAHRRFRSRR 132
Query: 169 HPAVSSTPVPQRSMAVSQPNLVMNHQHQQQMAPSTLSQQNHPTQNPPAGLMSMPNALTTQ 228
H + P P V +P ++ + +A +L P PPA P + T+
Sbjct: 133 HISEDLEPEPSEGGDVPEPWETIS--EEVNIAGDSLGLALPP---PPAS----PGSRTSP 183
Query: 229 QQQQQKLRLQRIQMERERIRMRQEELMRQEAALCRQLPMEAETLAPVQAAVNPPTMTPDM 288
Q+ ++L +R+Q+ + + L+++E + +L + T A + PP P
Sbjct: 184 QELSEELS-RRLQITPDSNGEQFSSLIQREPS--SRLRSCSVTDAVAEQGHLPPPSAPAG 240
Query: 289 RS 290
R+
Sbjct: 241 RA 242
>gi|114520609 neural precursor cell expressed, developmentally
down-regulated 4 isoform 1 [Homo sapiens]
Length = 900
Score = 47.0 bits (110), Expect = 3e-05
Identities = 23/48 (47%), Positives = 32/48 (66%), Gaps = 2/48 (4%)
Query: 111 AHLR-QQSYDVTDEL-PLPPGWEMTFTATGQRYFLNHIEKITTWQDPR 156
AHLR + S D +++L PLPPGWE G+ +++NH K T W+DPR
Sbjct: 458 AHLRGKTSLDTSNDLGPLPPGWEERTHTDGRIFYINHNIKRTQWEDPR 505
Score = 46.6 bits (109), Expect = 4e-05
Identities = 42/171 (24%), Positives = 68/171 (39%), Gaps = 23/171 (13%)
Query: 9 PLPPPGQQV---IHVTQDLDTDLEALFNSVMNPKPSSW----RKKILPESFFKEPDSGSH 61
P PPP + H+ ++L+ L NS ++ SS R+ L F+E +
Sbjct: 283 PSPPPSSNLDVPTHLAEELNARLTIFGNSAVSQPASSSNHSSRRGSLQAYTFEEQPTLPV 342
Query: 62 SRQSSTDSSGGHPGPRLAGGAQHVRSHSSPASL-------------QLGTGAGAAGSPAQ 108
+S+ G + G + H+S + QL + +AG +Q
Sbjct: 343 LLPTSSGLPPGWEEKQDERGRSYYVDHNSRTTTWTKPTVQATVETSQLTSSQSSAGPQSQ 402
Query: 109 QHAHLRQQSYDVTDELP---LPPGWEMTFTATGQRYFLNHIEKITTWQDPR 156
Q E+ LP GWE+ G+ +F++H K TTW+DPR
Sbjct: 403 ASTSDSGQQVTQPSEIEQGFLPKGWEVRHAPNGRPFFIDHNTKTTTWEDPR 453
Score = 40.4 bits (93), Expect = 0.003
Identities = 18/44 (40%), Positives = 25/44 (56%), Gaps = 4/44 (9%)
Query: 112 HLRQQSYDVTDELPLPPGWEMTFTATGQRYFLNHIEKITTWQDP 155
HL+QQ + PLPPGWE G+ Y++NH + T W+ P
Sbjct: 183 HLQQQQ----EPSPLPPGWEERQDILGRTYYVNHESRRTQWKRP 222
>gi|114520607 neural precursor cell expressed, developmentally
down-regulated 4 isoform 2 [Homo sapiens]
Length = 1247
Score = 47.0 bits (110), Expect = 3e-05
Identities = 23/48 (47%), Positives = 32/48 (66%), Gaps = 2/48 (4%)
Query: 111 AHLR-QQSYDVTDEL-PLPPGWEMTFTATGQRYFLNHIEKITTWQDPR 156
AHLR + S D +++L PLPPGWE G+ +++NH K T W+DPR
Sbjct: 805 AHLRGKTSLDTSNDLGPLPPGWEERTHTDGRIFYINHNIKRTQWEDPR 852
Score = 46.6 bits (109), Expect = 4e-05
Identities = 42/171 (24%), Positives = 68/171 (39%), Gaps = 23/171 (13%)
Query: 9 PLPPPGQQV---IHVTQDLDTDLEALFNSVMNPKPSSW----RKKILPESFFKEPDSGSH 61
P PPP + H+ ++L+ L NS ++ SS R+ L F+E +
Sbjct: 630 PSPPPSSNLDVPTHLAEELNARLTIFGNSAVSQPASSSNHSSRRGSLQAYTFEEQPTLPV 689
Query: 62 SRQSSTDSSGGHPGPRLAGGAQHVRSHSSPASL-------------QLGTGAGAAGSPAQ 108
+S+ G + G + H+S + QL + +AG +Q
Sbjct: 690 LLPTSSGLPPGWEEKQDERGRSYYVDHNSRTTTWTKPTVQATVETSQLTSSQSSAGPQSQ 749
Query: 109 QHAHLRQQSYDVTDELP---LPPGWEMTFTATGQRYFLNHIEKITTWQDPR 156
Q E+ LP GWE+ G+ +F++H K TTW+DPR
Sbjct: 750 ASTSDSGQQVTQPSEIEQGFLPKGWEVRHAPNGRPFFIDHNTKTTTWEDPR 800
Score = 40.4 bits (93), Expect = 0.003
Identities = 18/44 (40%), Positives = 25/44 (56%), Gaps = 4/44 (9%)
Query: 112 HLRQQSYDVTDELPLPPGWEMTFTATGQRYFLNHIEKITTWQDP 155
HL+QQ + PLPPGWE G+ Y++NH + T W+ P
Sbjct: 530 HLQQQQ----EPSPLPPGWEERQDILGRTYYVNHESRRTQWKRP 569
>gi|31317290 Smad ubiquitination regulatory factor 1 isoform 2 [Homo
sapiens]
Length = 731
Score = 46.6 bits (109), Expect = 4e-05
Identities = 50/199 (25%), Positives = 79/199 (39%), Gaps = 15/199 (7%)
Query: 62 SRQSSTDSSGGHPGPRLAGG-AQHVRSHSSPASLQLGTGAGAAGSPAQQHAHLRQQSYDV 120
S Q+ + GH P L G Q L TG P R +
Sbjct: 220 SLQTPQNRPHGHQSPELPEGYEQRTTVQGQVYFLHTQTGVSTWHDPRIP----RDLNSVN 275
Query: 121 TDEL-PLPPGWEMTFTATGQRYFLNHIEKITTWQDPRKAMNQPLNHM-NLHPAVSSTPVP 178
DEL PLPPGWE+ T +G+ YF++H + T + DPR ++ +NH L P+P
Sbjct: 276 CDELGPLPPGWEVRSTVSGRIYFVDHNNRTTQFTDPR--LHHIMNHQCQLKEPSQPLPLP 333
Query: 179 QRSMAVSQPNLVMNHQHQQQMAPSTLSQQNHPTQNPPAG----LMSMPNALTTQQQQQQK 234
++ L + + + + Q P AG +S +Q K
Sbjct: 334 SEG-SLEDEELPAQRYERDLVQKLKVLRHELSLQQPQAGHCRIEVSREEIFEESYRQIMK 392
Query: 235 LRLQRIQMERERIRMRQEE 253
+R + ++ +R ++ R EE
Sbjct: 393 MRPKDLK-KRLMVKFRGEE 410
>gi|12232397 SMAD specific E3 ubiquitin protein ligase 2 [Homo
sapiens]
Length = 748
Score = 46.6 bits (109), Expect = 4e-05
Identities = 19/36 (52%), Positives = 26/36 (72%)
Query: 125 PLPPGWEMTFTATGQRYFLNHIEKITTWQDPRKAMN 160
PLPPGWE+ TATG+ YF++H + T + DPR + N
Sbjct: 298 PLPPGWEIRNTATGRVYFVDHNNRTTQFTDPRLSAN 333
Score = 42.4 bits (98), Expect = 8e-04
Identities = 50/198 (25%), Positives = 85/198 (42%), Gaps = 35/198 (17%)
Query: 89 SSPASLQLGTGAGAAGSPAQQHAHLRQQ---SYDVTDELPLPP----GWEMTFTATGQRY 141
++P S G G + P +R Q +Y L PP G+E T GQ Y
Sbjct: 209 NTPISGTNGATCGQSSDPRLAERRVRSQRHRNYMSRTHLHTPPDLPEGYEQRTTQQGQVY 268
Query: 142 FLNHIEKITTWQDPRKAMNQPLNHMNLHPAVSSTPVPQ----RSMAVSQPNLVMNHQHQQ 197
FL+ ++TW DPR + + L+++N P+P R+ A + V ++
Sbjct: 269 FLHTQTGVSTWHDPR--VPRDLSNINCE---ELGPLPPGWEIRNTATGRVYFVDHNNRTT 323
Query: 198 QMAPSTLSQQNHPTQNPPAGLMSMPNALTTQQQQQ---------QKLRLQRIQMER-ERI 247
Q LS H +++ N L QQQQQ + L + R + + +++
Sbjct: 324 QFTDPRLSANLHL-------VLNRQNQLKDQQQQQVVSLCPDDTECLTVPRYKRDLVQKL 376
Query: 248 RMRQEELMRQ--EAALCR 263
++ ++EL +Q +A CR
Sbjct: 377 KILRQELSQQQPQAGHCR 394
Score = 38.5 bits (88), Expect = 0.011
Identities = 15/36 (41%), Positives = 23/36 (63%)
Query: 126 LPPGWEMTFTATGQRYFLNHIEKITTWQDPRKAMNQ 161
LP GWE TA+G+ +LNHI + T W+ P + ++
Sbjct: 159 LPDGWEERRTASGRIQYLNHITRTTQWERPTRPASE 194
>gi|13654239 WW domain containing E3 ubiquitin protein ligase 1
[Homo sapiens]
Length = 922
Score = 46.6 bits (109), Expect = 4e-05
Identities = 18/32 (56%), Positives = 22/32 (68%)
Query: 125 PLPPGWEMTFTATGQRYFLNHIEKITTWQDPR 156
PLPPGWE +T + YF+NH K T W+DPR
Sbjct: 457 PLPPGWEKRVDSTDRVYFVNHNTKTTQWEDPR 488
Score = 45.8 bits (107), Expect = 7e-05
Identities = 18/35 (51%), Positives = 26/35 (74%)
Query: 122 DELPLPPGWEMTFTATGQRYFLNHIEKITTWQDPR 156
+E PLP GWE+ +T G RYF++H + TT++DPR
Sbjct: 494 NEEPLPEGWEIRYTREGVRYFVDHNTRTTTFKDPR 528
Score = 39.7 bits (91), Expect = 0.005
Identities = 33/104 (31%), Positives = 48/104 (46%), Gaps = 6/104 (5%)
Query: 55 EPDSGSHSRQSSTDSSGGHPGPRLAGGAQHVRSHSSPASLQ-LGTGAGAAGSPAQQHAHL 113
EPD+ S+SR SS + P G VR S A+ + L +G P + ++
Sbjct: 312 EPDT-SNSRSSSAFEAAKSRQPD--GCMDPVRQQSGNANTETLPSGWEQRKDPHGRTYYV 368
Query: 114 RQQSYDVTDELP--LPPGWEMTFTATGQRYFLNHIEKITTWQDP 155
+ T E P LPPGWE + Y+++H + TTWQ P
Sbjct: 369 DHNTRTTTWERPQPLPPGWERRVDDRRRVYYVDHNTRTTTWQRP 412
Score = 37.4 bits (85), Expect = 0.024
Identities = 17/44 (38%), Positives = 26/44 (59%), Gaps = 1/44 (2%)
Query: 113 LRQQSYDVTDELPLPPGWEMTFTATGQRYFLNHIEKITTWQDPR 156
+RQQS + E LP GWE G+ Y+++H + TTW+ P+
Sbjct: 339 VRQQSGNANTET-LPSGWEQRKDPHGRTYYVDHNTRTTTWERPQ 381
>gi|27436957 membrane associated guanylate kinase, WW and PDZ domain
containing 2 [Homo sapiens]
Length = 1455
Score = 46.2 bits (108), Expect = 5e-05
Identities = 18/34 (52%), Positives = 23/34 (67%)
Query: 125 PLPPGWEMTFTATGQRYFLNHIEKITTWQDPRKA 158
PLP WEM +T G+ YF++H K T+W DPR A
Sbjct: 303 PLPDNWEMAYTEKGEVYFIDHNTKTTSWLDPRLA 336
>gi|31317292 Smad ubiquitination regulatory factor 1 isoform 1 [Homo
sapiens]
Length = 757
Score = 45.8 bits (107), Expect = 7e-05
Identities = 37/138 (26%), Positives = 63/138 (45%), Gaps = 10/138 (7%)
Query: 122 DEL-PLPPGWEMTFTATGQRYFLNHIEKITTWQDPRKAMNQPLNHM-NLHPAVSSTPVPQ 179
DEL PLPPGWE+ T +G+ YF++H + T + DPR ++ +NH L P+P
Sbjct: 303 DELGPLPPGWEVRSTVSGRIYFVDHNNRTTQFTDPR--LHHIMNHQCQLKEPSQPLPLPS 360
Query: 180 RSMAVSQPNLVMNHQHQQQMAPSTLSQQNHPTQNPPAG----LMSMPNALTTQQQQQQKL 235
++ L + + + + Q P AG +S +Q K+
Sbjct: 361 EG-SLEDEELPAQRYERDLVQKLKVLRHELSLQQPQAGHCRIEVSREEIFEESYRQIMKM 419
Query: 236 RLQRIQMERERIRMRQEE 253
R + ++ +R ++ R EE
Sbjct: 420 RPKDLK-KRLMVKFRGEE 436
Score = 37.7 bits (86), Expect = 0.019
Identities = 50/225 (22%), Positives = 86/225 (38%), Gaps = 35/225 (15%)
Query: 67 TDSSGGHPGPRLAGGAQHVRSHSSPASLQLGTGAGAAGSPAQQHAHLRQQSYDVTDELP- 125
TDS+G G G + V S S LQ A +P + + Q+ + P
Sbjct: 183 TDSTGAAAG---GGNCRFVESPSQDQRLQ----AQRLRNPDVRGSLQTPQNRPHGHQSPE 235
Query: 126 LPPGWEMTFTATGQRYFLNHIEKITTWQDPR------------------------KAMNQ 161
LP G+E T GQ YFL+ ++TW DPR + +
Sbjct: 236 LPEGYEQRTTVQGQVYFLHTQTGVSTWHDPRIPSPSGTIPGGDAAFLYEFLLQGHTSEPR 295
Query: 162 PLNHMNLHPAVSSTPVPQRSMAVSQPNLVMNHQHQ--QQMAPSTLSQQNHPTQ-NPPAGL 218
LN +N P + VS ++H ++ Q P NH Q P+
Sbjct: 296 DLNSVNCDELGPLPPGWEVRSTVSGRIYFVDHNNRTTQFTDPRLHHIMNHQCQLKEPSQP 355
Query: 219 MSMPNALTTQQQQQQKLRLQRIQMERERIRMRQEELMRQEAALCR 263
+ +P+ + + ++ R +R +++ ++ + L + +A CR
Sbjct: 356 LPLPSEGSLEDEELPAQRYERDLVQKLKVLRHELSLQQPQAGHCR 400
>gi|29789058 WW and C2 domain containing 1 isoform 3 [Homo sapiens]
Length = 1113
Score = 45.1 bits (105), Expect = 1e-04
Identities = 18/41 (43%), Positives = 25/41 (60%)
Query: 123 ELPLPPGWEMTFTATGQRYFLNHIEKITTWQDPRKAMNQPL 163
ELPLP GWE G+ Y+++H + T+W DPR +PL
Sbjct: 5 ELPLPEGWEEARDFDGKVYYIDHTNRTTSWIDPRDRYTKPL 45
Score = 38.5 bits (88), Expect = 0.011
Identities = 26/83 (31%), Positives = 37/83 (44%), Gaps = 5/83 (6%)
Query: 120 VTDELPLPPGWEMTFTATGQRYFLNHIEKITTWQDPRKAMNQPLNHM---NLHPAVSSTP 176
++DELPL GWE + YF++H K T +DPR + HM L A +
Sbjct: 51 ISDELPL--GWEEAYDPQVGDYFIDHNTKTTQIEDPRVQWRREQEHMLKDYLVVAQEALS 108
Query: 177 VPQRSMAVSQPNLVMNHQHQQQM 199
+ V Q L + Q QQ+
Sbjct: 109 AQKEIYQVKQQRLELAQQEYQQL 131
>gi|242247257 WW and C2 domain containing 1 isoform 2 [Homo sapiens]
Length = 1118
Score = 45.1 bits (105), Expect = 1e-04
Identities = 18/41 (43%), Positives = 25/41 (60%)
Query: 123 ELPLPPGWEMTFTATGQRYFLNHIEKITTWQDPRKAMNQPL 163
ELPLP GWE G+ Y+++H + T+W DPR +PL
Sbjct: 5 ELPLPEGWEEARDFDGKVYYIDHTNRTTSWIDPRDRYTKPL 45
Score = 38.5 bits (88), Expect = 0.011
Identities = 26/83 (31%), Positives = 37/83 (44%), Gaps = 5/83 (6%)
Query: 120 VTDELPLPPGWEMTFTATGQRYFLNHIEKITTWQDPRKAMNQPLNHM---NLHPAVSSTP 176
++DELPL GWE + YF++H K T +DPR + HM L A +
Sbjct: 51 ISDELPL--GWEEAYDPQVGDYFIDHNTKTTQIEDPRVQWRREQEHMLKDYLVVAQEALS 108
Query: 177 VPQRSMAVSQPNLVMNHQHQQQM 199
+ V Q L + Q QQ+
Sbjct: 109 AQKEIYQVKQQRLELAQQEYQQL 131
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.128 0.382
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,416,433
Number of Sequences: 37866
Number of extensions: 1079481
Number of successful extensions: 7502
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 111
Number of HSP's successfully gapped in prelim test: 183
Number of HSP's that attempted gapping in prelim test: 6117
Number of HSP's gapped (non-prelim): 1055
length of query: 400
length of database: 18,247,518
effective HSP length: 104
effective length of query: 296
effective length of database: 14,309,454
effective search space: 4235598384
effective search space used: 4235598384
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.