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Search of human proteins with 13325072
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13325072 phosphatidylinositol polyphosphate 5-phosphatase
isoform a [Homo sapiens]
(901 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13325072 phosphatidylinositol polyphosphate 5-phosphatase iso... 1836 0.0
gi|13325070 phosphatidylinositol polyphosphate 5-phosphatase iso... 1813 0.0
gi|113722125 inositol polyphosphate-5-phosphatase, 75kDa precurs... 784 0.0
gi|26190608 synaptojanin 2 [Homo sapiens] 223 6e-58
gi|237757312 synaptojanin 1 isoform c [Homo sapiens] 206 8e-53
gi|237757310 synaptojanin 1 isoform a [Homo sapiens] 206 8e-53
gi|237757308 synaptojanin 1 isoform b [Homo sapiens] 206 8e-53
gi|237757326 synaptojanin 1 isoform d [Homo sapiens] 206 8e-53
gi|50726960 phosphatidylinositol (4,5) bisphosphate 5-phosphatas... 174 4e-43
gi|222136583 inositol polyphosphate phosphatase-like 1 [Homo sap... 167 4e-41
gi|40254823 SH2 containing inositol phosphatase isoform b [Homo ... 162 1e-39
gi|64085167 SH2 containing inositol phosphatase isoform a [Homo ... 162 1e-39
gi|18765709 inositol polyphosphate-5-phosphatase K isoform 1 [Ho... 151 3e-36
gi|208610044 inositol polyphosphate-5-phosphatase K isoform 2 [H... 138 2e-32
gi|18765707 inositol polyphosphate-5-phosphatase K isoform 2 [Ho... 138 2e-32
gi|38327539 inositol polyphosphate-5-phosphatase E [Homo sapiens] 115 2e-25
gi|56119110 family with sequence similarity 13, member A1 isofor... 65 2e-10
gi|34013590 Rho GTPase activating protein 2 [Homo sapiens] 64 8e-10
gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo sa... 62 2e-09
gi|111154099 Rho GTPase activating protein 24 isoform 2 [Homo sa... 62 2e-09
gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo sa... 62 2e-09
gi|226423858 PRR5-ARHGAP8 fusion protein [Homo sapiens] 60 9e-09
gi|66346660 Rho GTPase activating protein 8 isoform 2 [Homo sapi... 60 9e-09
gi|66346662 Rho GTPase activating protein 8 isoform 1 [Homo sapi... 60 9e-09
gi|4757980 beta chimerin isoform 2 [Homo sapiens] 55 2e-07
gi|91106928 beta chimerin isoform 1 [Homo sapiens] 55 2e-07
gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens] 55 2e-07
gi|55770898 Rho GTPase activating protein 25 isoform a [Homo sap... 54 5e-07
gi|7661882 Rho GTPase activating protein 25 isoform b [Homo sapi... 54 5e-07
gi|134304853 PTPL1-associated RhoGAP 1 [Homo sapiens] 54 9e-07
>gi|13325072 phosphatidylinositol polyphosphate 5-phosphatase
isoform a [Homo sapiens]
Length = 901
Score = 1836 bits (4755), Expect = 0.0
Identities = 901/901 (100%), Positives = 901/901 (100%)
Query: 1 MEPPLPVGAQPLATVEGMEMKGPLREPCALTLAQRNGQYELIIQLHEKEQHVQDIIPINS 60
MEPPLPVGAQPLATVEGMEMKGPLREPCALTLAQRNGQYELIIQLHEKEQHVQDIIPINS
Sbjct: 1 MEPPLPVGAQPLATVEGMEMKGPLREPCALTLAQRNGQYELIIQLHEKEQHVQDIIPINS 60
Query: 61 HFRCVQEAEETLLIDIASNSGCKIRVQGDWIRERRFEIPDEEHCLKFLSAVLAAQKAQSQ 120
HFRCVQEAEETLLIDIASNSGCKIRVQGDWIRERRFEIPDEEHCLKFLSAVLAAQKAQSQ
Sbjct: 61 HFRCVQEAEETLLIDIASNSGCKIRVQGDWIRERRFEIPDEEHCLKFLSAVLAAQKAQSQ 120
Query: 121 LLVPEQKDSSSWYQKLDTKDKPSVFSGLLGFEDNFSSMNLDKKINSQNQPTGIHREPPPP 180
LLVPEQKDSSSWYQKLDTKDKPSVFSGLLGFEDNFSSMNLDKKINSQNQPTGIHREPPPP
Sbjct: 121 LLVPEQKDSSSWYQKLDTKDKPSVFSGLLGFEDNFSSMNLDKKINSQNQPTGIHREPPPP 180
Query: 181 PFSVNKMLPREKEASNKEQPKVTNTMRKLFVPNTQSGQREGLIKHILAKREKEYVNIQTF 240
PFSVNKMLPREKEASNKEQPKVTNTMRKLFVPNTQSGQREGLIKHILAKREKEYVNIQTF
Sbjct: 181 PFSVNKMLPREKEASNKEQPKVTNTMRKLFVPNTQSGQREGLIKHILAKREKEYVNIQTF 240
Query: 241 RFFVGTWNVNGQSPDSGLEPWLNCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSMA 300
RFFVGTWNVNGQSPDSGLEPWLNCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSMA
Sbjct: 241 RFFVGTWNVNGQSPDSGLEPWLNCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSMA 300
Query: 301 VERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVAV 360
VERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVAV
Sbjct: 301 VERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVAV 360
Query: 361 RFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHEVVIWL 420
RFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHEVVIWL
Sbjct: 361 RFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHEVVIWL 420
Query: 421 GDLNYRLCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKYD 480
GDLNYRLCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKYD
Sbjct: 421 GDLNYRLCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKYD 480
Query: 481 SKTDRWDSSGKCRVPAWCDRILWRGTNVNQLNYRSHMELKTSDHKPVSALFHIGVKVVDE 540
SKTDRWDSSGKCRVPAWCDRILWRGTNVNQLNYRSHMELKTSDHKPVSALFHIGVKVVDE
Sbjct: 481 SKTDRWDSSGKCRVPAWCDRILWRGTNVNQLNYRSHMELKTSDHKPVSALFHIGVKVVDE 540
Query: 541 RRYRKVFEDSVRIMDRMENDFLPSLELSRREFVFENVKFRQLQKEKFQISNNGQVPCHFS 600
RRYRKVFEDSVRIMDRMENDFLPSLELSRREFVFENVKFRQLQKEKFQISNNGQVPCHFS
Sbjct: 541 RRYRKVFEDSVRIMDRMENDFLPSLELSRREFVFENVKFRQLQKEKFQISNNGQVPCHFS 600
Query: 601 FIPKLNDSQYCKPWLRAEPFEGYLEPNETVDISLDVYVSKDSVTILNSGEDKIEDILVLH 660
FIPKLNDSQYCKPWLRAEPFEGYLEPNETVDISLDVYVSKDSVTILNSGEDKIEDILVLH
Sbjct: 601 FIPKLNDSQYCKPWLRAEPFEGYLEPNETVDISLDVYVSKDSVTILNSGEDKIEDILVLH 660
Query: 661 LDRGKDYFLTISGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLEEDSFLEKEKSLLQM 720
LDRGKDYFLTISGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLEEDSFLEKEKSLLQM
Sbjct: 661 LDRGKDYFLTISGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLEEDSFLEKEKSLLQM 720
Query: 721 VPLDEGASERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTSIPETI 780
VPLDEGASERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTSIPETI
Sbjct: 721 VPLDEGASERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTSIPETI 780
Query: 781 PGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQLPRCHRNVFRYLM 840
PGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQLPRCHRNVFRYLM
Sbjct: 781 PGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQLPRCHRNVFRYLM 840
Query: 841 AFLRELLKFSEYNSVNANMIATLFTSLLLRPPPNLMARQTPSDRQRAIQFLLGFLLGSEE 900
AFLRELLKFSEYNSVNANMIATLFTSLLLRPPPNLMARQTPSDRQRAIQFLLGFLLGSEE
Sbjct: 841 AFLRELLKFSEYNSVNANMIATLFTSLLLRPPPNLMARQTPSDRQRAIQFLLGFLLGSEE 900
Query: 901 D 901
D
Sbjct: 901 D 901
>gi|13325070 phosphatidylinositol polyphosphate 5-phosphatase
isoform b [Homo sapiens]
Length = 893
Score = 1813 bits (4696), Expect = 0.0
Identities = 893/901 (99%), Positives = 893/901 (99%), Gaps = 8/901 (0%)
Query: 1 MEPPLPVGAQPLATVEGMEMKGPLREPCALTLAQRNGQYELIIQLHEKEQHVQDIIPINS 60
MEPPLPVGAQPLATVEGMEMKGPLREPCALTLAQRNGQYELIIQLHEKEQHVQDIIPINS
Sbjct: 1 MEPPLPVGAQPLATVEGMEMKGPLREPCALTLAQRNGQYELIIQLHEKEQHVQDIIPINS 60
Query: 61 HFRCVQEAEETLLIDIASNSGCKIRVQGDWIRERRFEIPDEEHCLKFLSAVLAAQKAQSQ 120
HFRCVQEAEETLLIDIASNSGCKIRVQGDWIRERRFEIPDEEHCLKFLSAVLAAQKAQSQ
Sbjct: 61 HFRCVQEAEETLLIDIASNSGCKIRVQGDWIRERRFEIPDEEHCLKFLSAVLAAQKAQSQ 120
Query: 121 LLVPEQKDSSSWYQKLDTKDKPSVFSGLLGFEDNFSSMNLDKKINSQNQPTGIHREPPPP 180
LLVPEQKDSSSWYQKLDTKDKPSVFSGLLGFEDNFSSMNLDKKINSQNQPTGIHREPPPP
Sbjct: 121 LLVPEQKDSSSWYQKLDTKDKPSVFSGLLGFEDNFSSMNLDKKINSQNQPTGIHREPPPP 180
Query: 181 PFSVNKMLPREKEASNKEQPKVTNTMRKLFVPNTQSGQREGLIKHILAKREKEYVNIQTF 240
PFSVNKMLPREKEASNKEQPKVTNTMRKLFVPNTQSGQREGLIKHILAKREKEYVNIQTF
Sbjct: 181 PFSVNKMLPREKEASNKEQPKVTNTMRKLFVPNTQSGQREGLIKHILAKREKEYVNIQTF 240
Query: 241 RFFVGTWNVNGQSPDSGLEPWLNCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSMA 300
RFFVGTWNVNGQSPDSGLEPWLNCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSMA
Sbjct: 241 RFFVGTWNVNGQSPDSGLEPWLNCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSMA 300
Query: 301 VERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVAV 360
VERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVAV
Sbjct: 301 VERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVAV 360
Query: 361 RFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHEVVIWL 420
RFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHEVVIWL
Sbjct: 361 RFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHEVVIWL 420
Query: 421 GDLNYRLCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKYD 480
GDLNYRLCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKYD
Sbjct: 421 GDLNYRLCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKYD 480
Query: 481 SKTDRWDSSGKCRVPAWCDRILWRGTNVNQLNYRSHMELKTSDHKPVSALFHIGVKVVDE 540
SKTDRWDSSGKCRVPAWCDRILWRGTNVNQLNYRSHMELKTSDHKPVSALFHIGVKVVDE
Sbjct: 481 SKTDRWDSSGKCRVPAWCDRILWRGTNVNQLNYRSHMELKTSDHKPVSALFHIGVKVVDE 540
Query: 541 RRYRKVFEDSVRIMDRMENDFLPSLELSRREFVFENVKFRQLQKEKFQISNNGQVPCHFS 600
RRYRKVFEDSVRIMDRMENDFLPSLELSRREFVFENVKFRQLQKEKFQISNNGQVPCHFS
Sbjct: 541 RRYRKVFEDSVRIMDRMENDFLPSLELSRREFVFENVKFRQLQKEKFQISNNGQVPCHFS 600
Query: 601 FIPKLNDSQYCKPWLRAEPFEGYLEPNETVDISLDVYVSKDSVTILNSGEDKIEDILVLH 660
FIPKLNDSQYCKPWLRAEPFEGYLEPNETVDISLDVYVSKDSVTILNSGEDKIEDILVLH
Sbjct: 601 FIPKLNDSQYCKPWLRAEPFEGYLEPNETVDISLDVYVSKDSVTILNSGEDKIEDILVLH 660
Query: 661 LDRGKDYFLTISGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLEEDSFLEKEKSLLQM 720
LDRGKDYFLTISGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDL EKSLLQM
Sbjct: 661 LDRGKDYFLTISGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDL--------EKSLLQM 712
Query: 721 VPLDEGASERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTSIPETI 780
VPLDEGASERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTSIPETI
Sbjct: 713 VPLDEGASERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTSIPETI 772
Query: 781 PGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQLPRCHRNVFRYLM 840
PGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQLPRCHRNVFRYLM
Sbjct: 773 PGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQLPRCHRNVFRYLM 832
Query: 841 AFLRELLKFSEYNSVNANMIATLFTSLLLRPPPNLMARQTPSDRQRAIQFLLGFLLGSEE 900
AFLRELLKFSEYNSVNANMIATLFTSLLLRPPPNLMARQTPSDRQRAIQFLLGFLLGSEE
Sbjct: 833 AFLRELLKFSEYNSVNANMIATLFTSLLLRPPPNLMARQTPSDRQRAIQFLLGFLLGSEE 892
Query: 901 D 901
D
Sbjct: 893 D 893
>gi|113722125 inositol polyphosphate-5-phosphatase, 75kDa precursor
[Homo sapiens]
Length = 913
Score = 784 bits (2025), Expect = 0.0
Identities = 387/756 (51%), Positives = 528/756 (69%), Gaps = 40/756 (5%)
Query: 150 GFEDNFSSMNLDKKINSQNQPTGIHREPPPPPFSVNKMLPREKEASNKEQPKVTNTMR-- 207
G N + +D+ Q++P + PR+ NK + ++T+ +R
Sbjct: 184 GLRPNGKGVPMDQSSRGQDKPESLQ--------------PRQ----NKSKSEITDMVRSS 225
Query: 208 ------KLFVPNTQS-GQREGLIKHILAKREKEYVNIQTFRFFVGTWNVNGQSPDSGLEP 260
K + + Q G R+ ++K L ++E++Y IQ FRFF GT+NVNGQSP L
Sbjct: 226 TITVSDKAHILSMQKFGLRDTIVKSHLLQKEEDYTYIQNFRFFAGTYNVNGQSPKECLRL 285
Query: 261 WLNCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSMAVERGLHSKAKYKKVQLVRLV 320
WL+ PD+YC+GFQELDLS EAFF+ ++ KE+EW AV GLH AKY KV+L+RLV
Sbjct: 286 WLSNGIQAPDVYCVGFQELDLSKEAFFFHDTPKEEEWFKAVSEGLHPDAKYAKVKLIRLV 345
Query: 321 GMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVAVRFVFHNTTFCIVNSHLAAHV 380
G+MLL++ +++ YI ++ ETVGTGIMG+MGNKGGVA+RF FHNT+ C+VNSHLAAH+
Sbjct: 346 GIMLLLYVKQEHAAYISEVEAETVGTGIMGRMGNKGGVAIRFQFHNTSICVVNSHLAAHI 405
Query: 381 EDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHEVVIWLGDLNYRLCMPDANEVKSLIN 440
E++ERRNQDYKDIC+RM F P+ +LP L I H+V++WLGDLNYR+ D +VK LI
Sbjct: 406 EEYERRNQDYKDICSRMQFCQPDPSLPPLTISNHDVILWLGDLNYRIEELDVEKVKKLIE 465
Query: 441 KKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKYDSKTDRWDSSGKCRVPAWCDR 500
+KD Q L +DQL IQ K F F EGE+ F PTYKYD+ +D WD+S KCR PAWCDR
Sbjct: 466 EKDFQMLYAYDQLKIQVAAKTVFEGFTEGELTFQPTYKYDTGSDDWDTSEKCRAPAWCDR 525
Query: 501 ILWRGTNVNQLNYRSHMELKTSDHKPVSALFHIGVKVVDERRYRKVFEDSVRIMDRMEND 560
ILW+G N+ QL+Y+SHM LKTSDHKPVS++F IGV+VV++ YRK E+ VR +D+MEN
Sbjct: 526 ILWKGKNITQLSYQSHMALKTSDHKPVSSVFDIGVRVVNDELYRKTLEEIVRSLDKMENA 585
Query: 561 FLPSLELSRREFVFENVKFRQLQKEKFQISNNGQVPCHFSFIPKLNDSQYCKPWLRAEPF 620
+PS+ LS+REF F+NVK+ QL+ E F I +NGQVPCHF FI K ++ YCK WL A P
Sbjct: 586 NIPSVSLSKREFCFQNVKYMQLKVESFTI-HNGQVPCHFEFINKPDEESYCKQWLNANPS 644
Query: 621 EGYLEPNETVDISLDVYVSKDSVTILNSGEDKIEDILVLHLDRGKDYFLTISGNYLPSCF 680
G+L P+ V+I L+++V+K + T LNSGEDKIEDILVLHLDRGKDYFL++SGNYLPSCF
Sbjct: 645 RGFLLPDSDVEIDLELFVNKMTATKLNSGEDKIEDILVLHLDRGKDYFLSVSGNYLPSCF 704
Query: 681 GTSLEALCRMKRPIREVPVTKLIDLEEDSFLEKEKSLLQMVPLDEGAS-ERPLQVPKEIW 739
G+ + LC M+ PI ++P+ + +L +L+ + D+G+ + P+++PKE+W
Sbjct: 705 GSPIHTLCYMREPILDLPLETISEL----------TLMPVWTGDDGSQLDSPMEIPKELW 754
Query: 740 LLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTSIPETIPGSNHSVAEALLIFLEALP 799
++VD+L++ A QEDLFQ PG++ E + I DCLDT + + + SNHSVAEALL+FLE+LP
Sbjct: 755 MMVDYLYRNAVQQEDLFQQPGLRSEFEHIRDCLDTGMIDNLSASNHSVAEALLLFLESLP 814
Query: 800 EPVICYELYQRCLDSAYDPRICRQVISQLPRCHRNVFRYLMAFLRELLKFSEYNSVNANM 859
EPVICY Y CL+ + + +QVIS LP H+NVF YLMAFLRELLK S N ++ N+
Sbjct: 815 EPVICYSTYHNCLECSGNYTASKQVISTLPIFHKNVFHYLMAFLRELLKNSAKNHLDENI 874
Query: 860 IATLFTSLLLRPPPNLMARQTPSDRQRAIQFLLGFL 895
+A++F SLLLR P + +++++A +F+ FL
Sbjct: 875 LASIFGSLLLRNPAG-HQKLDMTEKKKAQEFIHQFL 909
>gi|26190608 synaptojanin 2 [Homo sapiens]
Length = 1496
Score = 223 bits (568), Expect = 6e-58
Identities = 127/371 (34%), Positives = 192/371 (51%), Gaps = 55/371 (14%)
Query: 227 LAKREKEYVNIQTFRFFVGTWNVNGQSP-------DSGLEPWL------------NCDPN 267
+ +R+ E+ N + R +GTWNVNG + L WL D +
Sbjct: 517 MTERQSEFTNFKRIRIAMGTWNVNGGKQFRSNVLRTAELTDWLLDSPQLSGATDSQDDSS 576
Query: 268 PPDIYCIGFQEL-DLSTEAFFYFESVKEQEWSMAVERGLHSKAKYKKVQLVRLVGMMLLI 326
P DI+ +GF+E+ +LS + ++ W +++ + +Y + +LVG+ L I
Sbjct: 577 PADIFAVGFEEMVELSAGNIVNASTTNKKMWGEQLQKAISRSHRYILLTSAQLVGVCLYI 636
Query: 327 FARKDQCRYIRDIATETVGTGIMGKMGNKGGVAVRFVFHNTTFCIVNSHLAAHVEDFERR 386
F R +IRD+A +TV TG+ GK GNKG V +RF FH+T+FC + SHL A + R
Sbjct: 637 FVRPYHVPFIRDVAIDTVKTGMGGKAGNKGAVGIRFQFHSTSFCFICSHLTAGQSQVKER 696
Query: 387 NQDYKDICARMSFVVPNQTLPQLNIMKHEVVIWLGDLNYRLCMPDANEVKSLINKKDLQR 446
N+DYK+I ++ F + N+ H+ V W GD NYR+ + EV + ++D ++
Sbjct: 697 NEDYKEITQKLCFPMGR------NVFSHDYVFWCGDFNYRIDL-TYEEVFYFVKRQDWKK 749
Query: 447 LLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKYDSKTDRWDSSGKCRVPAWCDRILW--- 503
LL+FDQL +Q++ K F DF+EG I F PTYKYD + +D+S KCR PAW DR+LW
Sbjct: 750 LLEFDQLQLQKSSGKIFKDFHEGAINFGPTYKYDVGSAAYDTSDKCRTPAWTDRVLWWRK 809
Query: 504 ------------------------RGT-NVNQLNYRSHMELKTSDHKPVSALFHIGVKVV 538
R T + L Y EL+ SDH+PV A+ + V+ V
Sbjct: 810 KHPFDKTAGELNLLDSDLDVDTKVRHTWSPGALQYYGRAELQASDHRPVLAIVEVEVQEV 869
Query: 539 DERRYRKVFED 549
D +VF++
Sbjct: 870 DVGARERVFQE 880
>gi|237757312 synaptojanin 1 isoform c [Homo sapiens]
Length = 1295
Score = 206 bits (524), Expect = 8e-53
Identities = 125/388 (32%), Positives = 194/388 (50%), Gaps = 56/388 (14%)
Query: 233 EYVNIQTFRFFVGTWNVNGQSP-------DSGLEPWLNCDPN-------------PPDIY 272
+Y + R VGTWNVNG + L WL P P DI+
Sbjct: 526 KYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIF 585
Query: 273 CIGFQEL-DLSTEAFFYFESVKEQEWSMAVERGLHSKAKYKKVQLVRLVGMMLLIFARKD 331
IGF+E+ +L+ + ++ W++ +++ + KY + +LVG+ L +F R
Sbjct: 586 AIGFEEMVELNAGNIVSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQ 645
Query: 332 QCRYIRDIATETVGTGIMGKMGNKGGVAVRFVFHNTTFCIVNSHLAAHVEDFERRNQDYK 391
+IRD+A +TV TG+ G GNKG VA+R +FH T+ C V SH AA + RN+D+
Sbjct: 646 HAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFI 705
Query: 392 DICARMSFVVPNQTLPQLNIMKHEVVIWLGDLNYRLCMPDANEVKSLINKKDLQRLLKFD 451
+I ++SF + + H+ V W GD NYR+ +P+ EVK LI +++ L+ D
Sbjct: 706 EIARKLSFPMGRM------LFSHDYVFWCGDFNYRIDLPN-EEVKELIRQQNWDSLIAGD 758
Query: 452 QLNIQRTQKKAFVDFNEGEIKFIPTYKYDSKTDRWDSSGKCRVPAWCDRILWR------- 504
QL Q+ + F F EG++ F PTYKYD +D +D+S KCR PAW DR+LWR
Sbjct: 759 QLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRRKWPFD 818
Query: 505 --GTNVNQLN-------------------YRSHMELKTSDHKPVSALFHIGVKVVDERRY 543
+++ LN + ELKTSDH+PV AL I + V+
Sbjct: 819 RSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEER 878
Query: 544 RKVFEDSVRIMDRMENDFLPSLELSRRE 571
+ ++++ + + + L S++ S E
Sbjct: 879 QNIYKEVIAVQGPPDGTVLVSIKSSLPE 906
>gi|237757310 synaptojanin 1 isoform a [Homo sapiens]
Length = 1612
Score = 206 bits (524), Expect = 8e-53
Identities = 125/388 (32%), Positives = 194/388 (50%), Gaps = 56/388 (14%)
Query: 233 EYVNIQTFRFFVGTWNVNGQSP-------DSGLEPWLNCDPN-------------PPDIY 272
+Y + R VGTWNVNG + L WL P P DI+
Sbjct: 565 KYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIF 624
Query: 273 CIGFQEL-DLSTEAFFYFESVKEQEWSMAVERGLHSKAKYKKVQLVRLVGMMLLIFARKD 331
IGF+E+ +L+ + ++ W++ +++ + KY + +LVG+ L +F R
Sbjct: 625 AIGFEEMVELNAGNIVSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQ 684
Query: 332 QCRYIRDIATETVGTGIMGKMGNKGGVAVRFVFHNTTFCIVNSHLAAHVEDFERRNQDYK 391
+IRD+A +TV TG+ G GNKG VA+R +FH T+ C V SH AA + RN+D+
Sbjct: 685 HAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFI 744
Query: 392 DICARMSFVVPNQTLPQLNIMKHEVVIWLGDLNYRLCMPDANEVKSLINKKDLQRLLKFD 451
+I ++SF + + H+ V W GD NYR+ +P+ EVK LI +++ L+ D
Sbjct: 745 EIARKLSFPMGRM------LFSHDYVFWCGDFNYRIDLPN-EEVKELIRQQNWDSLIAGD 797
Query: 452 QLNIQRTQKKAFVDFNEGEIKFIPTYKYDSKTDRWDSSGKCRVPAWCDRILWR------- 504
QL Q+ + F F EG++ F PTYKYD +D +D+S KCR PAW DR+LWR
Sbjct: 798 QLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRRKWPFD 857
Query: 505 --GTNVNQLN-------------------YRSHMELKTSDHKPVSALFHIGVKVVDERRY 543
+++ LN + ELKTSDH+PV AL I + V+
Sbjct: 858 RSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEER 917
Query: 544 RKVFEDSVRIMDRMENDFLPSLELSRRE 571
+ ++++ + + + L S++ S E
Sbjct: 918 QNIYKEVIAVQGPPDGTVLVSIKSSLPE 945
>gi|237757308 synaptojanin 1 isoform b [Homo sapiens]
Length = 1350
Score = 206 bits (524), Expect = 8e-53
Identities = 125/388 (32%), Positives = 194/388 (50%), Gaps = 56/388 (14%)
Query: 233 EYVNIQTFRFFVGTWNVNGQSP-------DSGLEPWLNCDPN-------------PPDIY 272
+Y + R VGTWNVNG + L WL P P DI+
Sbjct: 565 KYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIF 624
Query: 273 CIGFQEL-DLSTEAFFYFESVKEQEWSMAVERGLHSKAKYKKVQLVRLVGMMLLIFARKD 331
IGF+E+ +L+ + ++ W++ +++ + KY + +LVG+ L +F R
Sbjct: 625 AIGFEEMVELNAGNIVSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQ 684
Query: 332 QCRYIRDIATETVGTGIMGKMGNKGGVAVRFVFHNTTFCIVNSHLAAHVEDFERRNQDYK 391
+IRD+A +TV TG+ G GNKG VA+R +FH T+ C V SH AA + RN+D+
Sbjct: 685 HAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFI 744
Query: 392 DICARMSFVVPNQTLPQLNIMKHEVVIWLGDLNYRLCMPDANEVKSLINKKDLQRLLKFD 451
+I ++SF + + H+ V W GD NYR+ +P+ EVK LI +++ L+ D
Sbjct: 745 EIARKLSFPMGRM------LFSHDYVFWCGDFNYRIDLPN-EEVKELIRQQNWDSLIAGD 797
Query: 452 QLNIQRTQKKAFVDFNEGEIKFIPTYKYDSKTDRWDSSGKCRVPAWCDRILWR------- 504
QL Q+ + F F EG++ F PTYKYD +D +D+S KCR PAW DR+LWR
Sbjct: 798 QLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRRKWPFD 857
Query: 505 --GTNVNQLN-------------------YRSHMELKTSDHKPVSALFHIGVKVVDERRY 543
+++ LN + ELKTSDH+PV AL I + V+
Sbjct: 858 RSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEER 917
Query: 544 RKVFEDSVRIMDRMENDFLPSLELSRRE 571
+ ++++ + + + L S++ S E
Sbjct: 918 QNIYKEVIAVQGPPDGTVLVSIKSSLPE 945
>gi|237757326 synaptojanin 1 isoform d [Homo sapiens]
Length = 1526
Score = 206 bits (524), Expect = 8e-53
Identities = 125/388 (32%), Positives = 194/388 (50%), Gaps = 56/388 (14%)
Query: 233 EYVNIQTFRFFVGTWNVNGQSP-------DSGLEPWLNCDPN-------------PPDIY 272
+Y + R VGTWNVNG + L WL P P DI+
Sbjct: 521 KYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIF 580
Query: 273 CIGFQEL-DLSTEAFFYFESVKEQEWSMAVERGLHSKAKYKKVQLVRLVGMMLLIFARKD 331
IGF+E+ +L+ + ++ W++ +++ + KY + +LVG+ L +F R
Sbjct: 581 AIGFEEMVELNAGNIVSASTTNQKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQ 640
Query: 332 QCRYIRDIATETVGTGIMGKMGNKGGVAVRFVFHNTTFCIVNSHLAAHVEDFERRNQDYK 391
+IRD+A +TV TG+ G GNKG VA+R +FH T+ C V SH AA + RN+D+
Sbjct: 641 HAPFIRDVAVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFI 700
Query: 392 DICARMSFVVPNQTLPQLNIMKHEVVIWLGDLNYRLCMPDANEVKSLINKKDLQRLLKFD 451
+I ++SF + + H+ V W GD NYR+ +P+ EVK LI +++ L+ D
Sbjct: 701 EIARKLSFPMGRM------LFSHDYVFWCGDFNYRIDLPN-EEVKELIRQQNWDSLIAGD 753
Query: 452 QLNIQRTQKKAFVDFNEGEIKFIPTYKYDSKTDRWDSSGKCRVPAWCDRILWR------- 504
QL Q+ + F F EG++ F PTYKYD +D +D+S KCR PAW DR+LWR
Sbjct: 754 QLINQKNAGQVFRGFLEGKVTFAPTYKYDLFSDDYDTSEKCRTPAWTDRVLWRRRKWPFD 813
Query: 505 --GTNVNQLN-------------------YRSHMELKTSDHKPVSALFHIGVKVVDERRY 543
+++ LN + ELKTSDH+PV AL I + V+
Sbjct: 814 RSAEDLDLLNASFQDESKILYTWTPGTLLHYGRAELKTSDHRPVVALIDIDIFEVEAEER 873
Query: 544 RKVFEDSVRIMDRMENDFLPSLELSRRE 571
+ ++++ + + + L S++ S E
Sbjct: 874 QNIYKEVIAVQGPPDGTVLVSIKSSLPE 901
>gi|50726960 phosphatidylinositol (4,5) bisphosphate 5-phosphatase,
A [Homo sapiens]
Length = 638
Score = 174 bits (440), Expect = 4e-43
Identities = 106/311 (34%), Positives = 157/311 (50%), Gaps = 26/311 (8%)
Query: 241 RFFVGTWNVNGQSPDSGLEPWLNC----DPNPPDIYCIGFQELDLSTEAFFYFESVKEQE 296
R V TWNV P + L+ D + D+ IG QE++ +++ +
Sbjct: 56 RITVVTWNVGTAMPPDDVTSLLHLGGGDDSDGADMIAIGLQEVNSMLNKRLK-DALFTDQ 114
Query: 297 WSMAVERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKG 356
WS L + V VR+ G++LL+FA+ ++RD+ T+ TG+ G GNKG
Sbjct: 115 WSELFMDAL-GPFNFVLVSSVRMQGVILLLFAKYYHLPFLRDVQTDCTRTGLGGYWGNKG 173
Query: 357 GVAVRFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHEV 416
GV+VR C +N HL AH++ E+R +++ I + F P I+ H++
Sbjct: 174 GVSVRLAAFGHMLCFLNCHLPAHMDKAEQRKDNFQTILSLQQFQGPGAQ----GILDHDL 229
Query: 417 VIWLGDLNYRLCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPT 476
V W GDLN+R+ D + VK I+ L +L + DQLN+ + F EG + F PT
Sbjct: 230 VFWFGDLNFRIESYDLHFVKFAIDSDQLHQLWEKDQLNMAKNTWPILKGFQEGPLNFAPT 289
Query: 477 YKYDSKTDRWDSSGKCRVPAWCDRILWR----------------GTNVNQLNYRSHMELK 520
+K+D T+++D+S K R PAW DRILW+ V Q +YRSHME
Sbjct: 290 FKFDVGTNKYDTSAKKRKPAWTDRILWKVKAPGGGPSPSGRKSHRLQVTQHSYRSHMEYT 349
Query: 521 TSDHKPVSALF 531
SDHKPV+A F
Sbjct: 350 VSDHKPVAAQF 360
>gi|222136583 inositol polyphosphate phosphatase-like 1 [Homo
sapiens]
Length = 1258
Score = 167 bits (423), Expect = 4e-41
Identities = 106/317 (33%), Positives = 162/317 (51%), Gaps = 38/317 (11%)
Query: 243 FVGTWNVNGQSPDSGLEPWLNCD-----------PNPPDIYCIGFQELDLSTEAFFYFES 291
F+GTWN+ P + W P DIY G QE S
Sbjct: 427 FIGTWNMGSVPPPKNVTSWFTSKGLGKTLDEVTVTIPHDIYVFGTQE-----------NS 475
Query: 292 VKEQEWSMAVERGLH--SKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIM 349
V ++EW + GL + Y+ + + L + + + + + I ++T +V TGI
Sbjct: 476 VGDREWLDLLRGGLKELTDLDYRPIAMQSLWNIKVAVLVKPEHENRISHVSTSSVKTGIA 535
Query: 350 GKMGNKGGVAVRFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQL 409
+GNKG V V F+F+ T+F VN HL + E RRNQ+Y DI +S + ++ L
Sbjct: 536 NTLGNKGAVGVSFMFNGTSFGFVNCHLTSGNEKTARRNQNYLDILRLLS--LGDRQLNAF 593
Query: 410 NI-MKHEVVIWLGDLNYRLCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNE 468
+I ++ + W GDLNYRL M D E+ + I++K+ + LL+ DQLN++R + K F+ F+E
Sbjct: 594 DISLRFTHLFWFGDLNYRLDM-DIQEILNYISRKEFEPLLRVDQLNLEREKHKVFLRFSE 652
Query: 469 GEIKFIPTYKYD---SKTDRW----DSSGKCRVPAWCDRILWRG---TNVNQLNYRSHME 518
EI F PTY+Y+ T W + + VP+WCDRILW+ T++ +Y +
Sbjct: 653 EEISFPPTYRYERGSRDTYAWHKQKPTGVRTNVPSWCDRILWKSYPETHIICNSYGCTDD 712
Query: 519 LKTSDHKPVSALFHIGV 535
+ TSDH PV F +GV
Sbjct: 713 IVTSDHSPVFGTFEVGV 729
>gi|40254823 SH2 containing inositol phosphatase isoform b [Homo
sapiens]
Length = 1188
Score = 162 bits (410), Expect = 1e-39
Identities = 114/358 (31%), Positives = 175/358 (48%), Gaps = 42/358 (11%)
Query: 206 MRKLFVPNTQSGQREGLIKHILAKREK--EYVNIQTFRFFVGTWNVNGQSPDSGLEPWL- 262
+RK +V S +REG + + + K E F+GTWN+ P + W
Sbjct: 368 LRKEYV-FADSKKREGFCQLLQQMKNKHSEQPEPDMITIFIGTWNMGNAPPPKKITSWFL 426
Query: 263 ----------NCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSMAVERGLH--SKAK 310
+ D P DIY IG QE LS E+EW ++ L +
Sbjct: 427 SKGQGKTRDDSADYIPHDIYVIGTQEDPLS-----------EKEWLEILKHSLQEITSVT 475
Query: 311 YKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVAVRFVFHNTTFC 370
+K V + L + +++ A+ + I I T+ V TGI +GNKG V V F+F+ T+
Sbjct: 476 FKTVAIHTLWNIRIVVLAKPEHENRISHICTDNVKTGIANTLGNKGAVGVSFMFNGTSLG 535
Query: 371 IVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIM-KHEVVIWLGDLNYRLCM 429
VNSHL + E RRNQ+Y +I ++ + ++ L NI + + W GDLNYR+ +
Sbjct: 536 FVNSHLTSGSEKKLRRNQNYMNILRFLA--LGDKKLSPFNITHRFTHLFWFGDLNYRVDL 593
Query: 430 P--DANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKYD------- 480
P +A + I ++ LL DQL +R ++K F+ F E EI F PTY+++
Sbjct: 594 PTWEAETIIQKIKQQQYADLLSHDQLLTERREQKVFLHFEEEEITFAPTYRFERLTRDKY 653
Query: 481 SKTDRWDSSGKCRVPAWCDRILWRG---TNVNQLNYRSHMELKTSDHKPVSALFHIGV 535
+ T + + K +P+WCDR+LW+ +V +Y S ++ TSDH PV A F GV
Sbjct: 654 AYTKQKATGMKYNLPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGV 711
>gi|64085167 SH2 containing inositol phosphatase isoform a [Homo
sapiens]
Length = 1189
Score = 162 bits (410), Expect = 1e-39
Identities = 114/358 (31%), Positives = 175/358 (48%), Gaps = 42/358 (11%)
Query: 206 MRKLFVPNTQSGQREGLIKHILAKREK--EYVNIQTFRFFVGTWNVNGQSPDSGLEPWL- 262
+RK +V S +REG + + + K E F+GTWN+ P + W
Sbjct: 369 LRKEYV-FADSKKREGFCQLLQQMKNKHSEQPEPDMITIFIGTWNMGNAPPPKKITSWFL 427
Query: 263 ----------NCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEWSMAVERGLH--SKAK 310
+ D P DIY IG QE LS E+EW ++ L +
Sbjct: 428 SKGQGKTRDDSADYIPHDIYVIGTQEDPLS-----------EKEWLEILKHSLQEITSVT 476
Query: 311 YKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVAVRFVFHNTTFC 370
+K V + L + +++ A+ + I I T+ V TGI +GNKG V V F+F+ T+
Sbjct: 477 FKTVAIHTLWNIRIVVLAKPEHENRISHICTDNVKTGIANTLGNKGAVGVSFMFNGTSLG 536
Query: 371 IVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIM-KHEVVIWLGDLNYRLCM 429
VNSHL + E RRNQ+Y +I ++ + ++ L NI + + W GDLNYR+ +
Sbjct: 537 FVNSHLTSGSEKKLRRNQNYMNILRFLA--LGDKKLSPFNITHRFTHLFWFGDLNYRVDL 594
Query: 430 P--DANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKYD------- 480
P +A + I ++ LL DQL +R ++K F+ F E EI F PTY+++
Sbjct: 595 PTWEAETIIQKIKQQQYADLLSHDQLLTERREQKVFLHFEEEEITFAPTYRFERLTRDKY 654
Query: 481 SKTDRWDSSGKCRVPAWCDRILWRG---TNVNQLNYRSHMELKTSDHKPVSALFHIGV 535
+ T + + K +P+WCDR+LW+ +V +Y S ++ TSDH PV A F GV
Sbjct: 655 AYTKQKATGMKYNLPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGV 712
>gi|18765709 inositol polyphosphate-5-phosphatase K isoform 1 [Homo
sapiens]
Length = 448
Score = 151 bits (381), Expect = 3e-36
Identities = 100/312 (32%), Positives = 155/312 (49%), Gaps = 25/312 (8%)
Query: 244 VGTWNVNGQSPDSGLEPWLNCDPNPP--DIYCIGFQELDLSTEAFFYFESVKEQEWSMAV 301
V TWNV +P L L + DIY IG QEL+ + ++ WS +
Sbjct: 18 VVTWNVASAAPPLDLSDLLQLNNRNLNLDIYVIGLQELNSGIISLLS-DAAFNDSWSSFL 76
Query: 302 ERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVAVR 361
L S + KV VR+ G++LL+FA+ YI+ ++T++ TG+ G GNKGGV +
Sbjct: 77 MDVL-SPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNIC 135
Query: 362 FVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHEVVIWLG 421
+ I+N HL H+ + +R + + I + + +P NI+ H+++IW G
Sbjct: 136 LKLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQN--CEGRDIP--NILDHDLIIWFG 191
Query: 422 DLNYRLCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKYDS 481
D+N+R+ + V+ I + L + DQL+I + +F EG + F PTYK+D
Sbjct: 192 DMNFRIEDFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDR 251
Query: 482 KTDRWDSSGKCRVPAWCDRILWR-----------------GTNVNQLNYRSHMELKTSDH 524
++ +D+S K R PAW DRILWR +++ Y SHM SDH
Sbjct: 252 NSNDYDTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGISDH 311
Query: 525 KPVSALFHIGVK 536
KPVS F + +K
Sbjct: 312 KPVSGTFDLELK 323
>gi|208610044 inositol polyphosphate-5-phosphatase K isoform 2 [Homo
sapiens]
Length = 372
Score = 138 bits (348), Expect = 2e-32
Identities = 81/247 (32%), Positives = 129/247 (52%), Gaps = 21/247 (8%)
Query: 307 SKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVAVRFVFHN 366
S + KV VR+ G++LL+FA+ YI+ ++T++ TG+ G GNKGGV + +
Sbjct: 5 SPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLYG 64
Query: 367 TTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHEVVIWLGDLNYR 426
I+N HL H+ + +R + + I + + +P NI+ H+++IW GD+N+R
Sbjct: 65 YYVSIINCHLPPHISNNYQRLEHFDRILEMQN--CEGRDIP--NILDHDLIIWFGDMNFR 120
Query: 427 LCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKYDSKTDRW 486
+ + V+ I + L + DQL+I + +F EG + F PTYK+D ++ +
Sbjct: 121 IEDFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDY 180
Query: 487 DSSGKCRVPAWCDRILWR-----------------GTNVNQLNYRSHMELKTSDHKPVSA 529
D+S K R PAW DRILWR +++ Y SHM SDHKPVS
Sbjct: 181 DTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGISDHKPVSG 240
Query: 530 LFHIGVK 536
F + +K
Sbjct: 241 TFDLELK 247
>gi|18765707 inositol polyphosphate-5-phosphatase K isoform 2 [Homo
sapiens]
Length = 372
Score = 138 bits (348), Expect = 2e-32
Identities = 81/247 (32%), Positives = 129/247 (52%), Gaps = 21/247 (8%)
Query: 307 SKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVAVRFVFHN 366
S + KV VR+ G++LL+FA+ YI+ ++T++ TG+ G GNKGGV + +
Sbjct: 5 SPLSFIKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLYG 64
Query: 367 TTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHEVVIWLGDLNYR 426
I+N HL H+ + +R + + I + + +P NI+ H+++IW GD+N+R
Sbjct: 65 YYVSIINCHLPPHISNNYQRLEHFDRILEMQN--CEGRDIP--NILDHDLIIWFGDMNFR 120
Query: 427 LCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTYKYDSKTDRW 486
+ + V+ I + L + DQL+I + +F EG + F PTYK+D ++ +
Sbjct: 121 IEDFGLHFVRESIKNRCYGGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDY 180
Query: 487 DSSGKCRVPAWCDRILWR-----------------GTNVNQLNYRSHMELKTSDHKPVSA 529
D+S K R PAW DRILWR +++ Y SHM SDHKPVS
Sbjct: 181 DTSEKKRKPAWTDRILWRLKRQPCAGPDTPIPPASHFSLSLRGYSSHMTYGISDHKPVSG 240
Query: 530 LFHIGVK 536
F + +K
Sbjct: 241 TFDLELK 247
>gi|38327539 inositol polyphosphate-5-phosphatase E [Homo sapiens]
Length = 644
Score = 115 bits (287), Expect = 2e-25
Identities = 90/313 (28%), Positives = 145/313 (46%), Gaps = 37/313 (11%)
Query: 243 FVGTWNVNGQS--PDSGLEPWLNCDPN-PPDIYCIGFQELDLSTEAFFYFESVKEQEWSM 299
FV TWN+ GQ P S E L + + D+Y IG QE +EW
Sbjct: 302 FVATWNMQGQKELPPSLDEFLLPAEADYAQDLYVIGVQE-----------GCSDRREWET 350
Query: 300 AVERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGGVA 359
++ L Y + + + +F R+D + ++ TV T I+ ++ KG +
Sbjct: 351 RLQETLGPH--YVLLSSAAHGVLYMSLFIRRDLIWFCSEVECSTVTTRIVSQIKTKGALG 408
Query: 360 VRFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLN--------- 410
+ F F T+F + SH + R DY + V+P + +P N
Sbjct: 409 ISFTFFGTSFLFITSHFTSGDGKVAERLLDYTRTV--QALVLP-RNVPDTNPYRSSAADV 465
Query: 411 IMKHEVVIWLGDLNYRLC----MPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDF 466
+ + V W GD N+RL + DA + L+ D+ LL+ DQL + + F F
Sbjct: 466 TTRFDEVFWFGDFNFRLSGGRTVVDALLCQGLV--VDVPALLQHDQLIREMRKGSIFKGF 523
Query: 467 NEGEIKFIPTYKYDSKTDRWDSSGKCRVPAWCDRILWRGT---NVNQLNYRSHMELKTSD 523
E +I F+P+YK+D D +DS+ K R P++ DR+L+R ++ ++Y S +KTSD
Sbjct: 524 QEPDIHFLPSYKFDIGKDTYDSTSKQRTPSYTDRVLYRSRHKGDICPVSYSSCPGIKTSD 583
Query: 524 HKPVSALFHIGVK 536
H+PV LF + V+
Sbjct: 584 HRPVYGLFRVKVR 596
>gi|56119110 family with sequence similarity 13, member A1 isoform a
[Homo sapiens]
Length = 1023
Score = 65.5 bits (158), Expect = 2e-10
Identities = 53/208 (25%), Positives = 99/208 (47%), Gaps = 15/208 (7%)
Query: 681 GTSLEALCRMKRPIR-EVPVTKLIDL---EEDSFLEKEKSLLQMVPLD-EGASERPLQVP 735
G A+C+ K +R + + K++ + E+ F ++ + + L+ +G +E +P
Sbjct: 2 GAGALAICQSKAAVRLKEDMKKIVAVPLNEQKDFTYQKLFGVSLQELERQGLTENG--IP 59
Query: 736 KEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTSIPETI--PGSNHSVAEALLI 793
+W +V++L ++ QE LF+ G + ++Q+ ++ +P + G S A L +
Sbjct: 60 AVVWNIVEYLTQHGLTQEGLFRVNGNVKVVEQLRLKFESGVPVELGKDGDVCSAASLLKL 119
Query: 794 FLEALPEPVICYELYQRCLDSAYDPR------ICRQVISQLPRCHRNVFRYLMAFLRELL 847
FL LP+ +I L R + D R R +I +LP H + +YL FL ++
Sbjct: 120 FLRELPDSLITSALQPRFIQLFQDGRNDVQESSLRDLIKELPDTHYCLLKYLCQFLTKVA 179
Query: 848 KFSEYNSVNANMIATLFTSLLLRPPPNL 875
K N +N + +AT+F PP L
Sbjct: 180 KHHVQNRMNVHNLATVFGPNCFHVPPGL 207
>gi|34013590 Rho GTPase activating protein 2 [Homo sapiens]
Length = 698
Score = 63.5 bits (153), Expect = 8e-10
Identities = 45/153 (29%), Positives = 75/153 (49%), Gaps = 14/153 (9%)
Query: 731 PLQVPKEIWLLVDHLFKYACHQEDLFQTPG---MQEELQQIIDCLDTSIPETIPGSNHSV 787
P P + VD + + +E LF+ PG + +LQ DC + + ++ H+V
Sbjct: 169 PRLAPLLVEQCVDFIRERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFDSTTDV-HTV 227
Query: 788 AEALLIFLEALPEPVICYELYQRCLDSAY---------DPRICRQVISQLPRCHRNVFRY 838
A L ++L LPEPV+ + Y+ L A + +QV S LP+ + N+ RY
Sbjct: 228 ASLLKLYLRELPEPVVPFARYEDFLSCAQLLTKDEGEGTLELAKQV-SNLPQANYNLLRY 286
Query: 839 LMAFLRELLKFSEYNSVNANMIATLFTSLLLRP 871
+ FL E+ +S N ++ +AT+F +LRP
Sbjct: 287 ICKFLDEVQAYSNVNKMSVQNLATVFGPNILRP 319
>gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo
sapiens]
Length = 653
Score = 62.0 bits (149), Expect = 2e-09
Identities = 42/141 (29%), Positives = 70/141 (49%), Gaps = 12/141 (8%)
Query: 742 VDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTSIPETIPGSN--HSVAEALLIFLEALP 799
VD + + +E LF+ PG ++++ D D + + H+VA L ++L LP
Sbjct: 65 VDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVASLLKLYLRELP 124
Query: 800 EPVICYELYQRCL---------DSAYDPRICRQVISQLPRCHRNVFRYLMAFLRELLKFS 850
EPVI Y Y+ L + A + +QV S LP + N+ +Y+ FL E+ +S
Sbjct: 125 EPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKS-LPVVNYNLLKYICRFLDEVQSYS 183
Query: 851 EYNSVNANMIATLFTSLLLRP 871
N ++ +AT+F +LRP
Sbjct: 184 GVNKMSVQNLATVFGPNILRP 204
>gi|111154099 Rho GTPase activating protein 24 isoform 2 [Homo
sapiens]
Length = 655
Score = 62.0 bits (149), Expect = 2e-09
Identities = 42/141 (29%), Positives = 70/141 (49%), Gaps = 12/141 (8%)
Query: 742 VDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTSIPETIPGSN--HSVAEALLIFLEALP 799
VD + + +E LF+ PG ++++ D D + + H+VA L ++L LP
Sbjct: 67 VDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVASLLKLYLRELP 126
Query: 800 EPVICYELYQRCL---------DSAYDPRICRQVISQLPRCHRNVFRYLMAFLRELLKFS 850
EPVI Y Y+ L + A + +QV S LP + N+ +Y+ FL E+ +S
Sbjct: 127 EPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKS-LPVVNYNLLKYICRFLDEVQSYS 185
Query: 851 EYNSVNANMIATLFTSLLLRP 871
N ++ +AT+F +LRP
Sbjct: 186 GVNKMSVQNLATVFGPNILRP 206
>gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo
sapiens]
Length = 748
Score = 62.0 bits (149), Expect = 2e-09
Identities = 42/141 (29%), Positives = 70/141 (49%), Gaps = 12/141 (8%)
Query: 742 VDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTSIPETIPGSN--HSVAEALLIFLEALP 799
VD + + +E LF+ PG ++++ D D + + H+VA L ++L LP
Sbjct: 160 VDFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVASLLKLYLRELP 219
Query: 800 EPVICYELYQRCL---------DSAYDPRICRQVISQLPRCHRNVFRYLMAFLRELLKFS 850
EPVI Y Y+ L + A + +QV S LP + N+ +Y+ FL E+ +S
Sbjct: 220 EPVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKS-LPVVNYNLLKYICRFLDEVQSYS 278
Query: 851 EYNSVNANMIATLFTSLLLRP 871
N ++ +AT+F +LRP
Sbjct: 279 GVNKMSVQNLATVFGPNILRP 299
>gi|226423858 PRR5-ARHGAP8 fusion protein [Homo sapiens]
Length = 555
Score = 60.1 bits (144), Expect = 9e-09
Identities = 39/145 (26%), Positives = 71/145 (48%), Gaps = 7/145 (4%)
Query: 734 VPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTSIPETIP--GSNHSVAEAL 791
+P + V +L + E LF+ + +++I + P G H A L
Sbjct: 331 IPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGDIHIPAVIL 390
Query: 792 LIFLEALPEPVICYELYQR-----CLDSAYDPRICRQVISQLPRCHRNVFRYLMAFLREL 846
FL LP+P++ ++ Y++ C++S+ CRQ++ LP + V RYLM FL +
Sbjct: 391 KTFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQILRSLPEHNYVVLRYLMGFLHAV 450
Query: 847 LKFSEYNSVNANMIATLFTSLLLRP 871
+ S +N +N++ +A +F L+ P
Sbjct: 451 SRESIFNKMNSSNLACVFGLNLIWP 475
>gi|66346660 Rho GTPase activating protein 8 isoform 2 [Homo
sapiens]
Length = 433
Score = 60.1 bits (144), Expect = 9e-09
Identities = 39/145 (26%), Positives = 71/145 (48%), Gaps = 7/145 (4%)
Query: 734 VPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTSIPETIP--GSNHSVAEAL 791
+P + V +L + E LF+ + +++I + P G H A L
Sbjct: 209 IPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGDIHIPAVIL 268
Query: 792 LIFLEALPEPVICYELYQR-----CLDSAYDPRICRQVISQLPRCHRNVFRYLMAFLREL 846
FL LP+P++ ++ Y++ C++S+ CRQ++ LP + V RYLM FL +
Sbjct: 269 KTFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQILRSLPEHNYVVLRYLMGFLHAV 328
Query: 847 LKFSEYNSVNANMIATLFTSLLLRP 871
+ S +N +N++ +A +F L+ P
Sbjct: 329 SRESIFNKMNSSNLACVFGLNLIWP 353
>gi|66346662 Rho GTPase activating protein 8 isoform 1 [Homo
sapiens]
Length = 464
Score = 60.1 bits (144), Expect = 9e-09
Identities = 39/145 (26%), Positives = 71/145 (48%), Gaps = 7/145 (4%)
Query: 734 VPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTSIPETIP--GSNHSVAEAL 791
+P + V +L + E LF+ + +++I + P G H A L
Sbjct: 240 IPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGDIHIPAVIL 299
Query: 792 LIFLEALPEPVICYELYQR-----CLDSAYDPRICRQVISQLPRCHRNVFRYLMAFLREL 846
FL LP+P++ ++ Y++ C++S+ CRQ++ LP + V RYLM FL +
Sbjct: 300 KTFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQILRSLPEHNYVVLRYLMGFLHAV 359
Query: 847 LKFSEYNSVNANMIATLFTSLLLRP 871
+ S +N +N++ +A +F L+ P
Sbjct: 360 SRESIFNKMNSSNLACVFGLNLIWP 384
>gi|4757980 beta chimerin isoform 2 [Homo sapiens]
Length = 468
Score = 55.5 bits (132), Expect = 2e-07
Identities = 38/151 (25%), Positives = 67/151 (44%), Gaps = 11/151 (7%)
Query: 733 QVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLD-----TSIPETIPGSNHSV 787
Q P + + + + E L++ G E ++ + D I + + +
Sbjct: 289 QRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINII 348
Query: 788 AEALLIFLEALPEPVICYELYQRCLDSAY----DPRI--CRQVISQLPRCHRNVFRYLMA 841
AL ++ LP PVI Y+ Y + +D+A D R+ +V+ LP H RYLM
Sbjct: 349 TGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLMI 408
Query: 842 FLRELLKFSEYNSVNANMIATLFTSLLLRPP 872
L+++ + N +NA + +F L+RPP
Sbjct: 409 HLKKVTMNEKDNFMNAENLGIVFGPTLMRPP 439
>gi|91106928 beta chimerin isoform 1 [Homo sapiens]
Length = 332
Score = 55.5 bits (132), Expect = 2e-07
Identities = 38/151 (25%), Positives = 67/151 (44%), Gaps = 11/151 (7%)
Query: 733 QVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLD-----TSIPETIPGSNHSV 787
Q P + + + + E L++ G E ++ + D I + + +
Sbjct: 153 QRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINII 212
Query: 788 AEALLIFLEALPEPVICYELYQRCLDSAY----DPRI--CRQVISQLPRCHRNVFRYLMA 841
AL ++ LP PVI Y+ Y + +D+A D R+ +V+ LP H RYLM
Sbjct: 213 TGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLMI 272
Query: 842 FLRELLKFSEYNSVNANMIATLFTSLLLRPP 872
L+++ + N +NA + +F L+RPP
Sbjct: 273 HLKKVTMNEKDNFMNAENLGIVFGPTLMRPP 303
>gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens]
Length = 818
Score = 55.5 bits (132), Expect = 2e-07
Identities = 40/159 (25%), Positives = 76/159 (47%), Gaps = 10/159 (6%)
Query: 722 PLDEGASERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQI---IDCLDTSIPE 778
PL+E + ++ I V L + +E LF+ +L+++ +DC + E
Sbjct: 256 PLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCVVDVQE 315
Query: 779 TIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSA----YDPRI--CRQVISQLPRCH 832
H++A AL +L LPEP++ +ELY + ++ D ++ +LP+ +
Sbjct: 316 -YSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEKLPKAN 374
Query: 833 RNVFRYLMAFLRELLKFSEYNSVNANMIATLFTSLLLRP 871
N RYL+ FL +L ++ + N + + +A + LL P
Sbjct: 375 HNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWP 413
>gi|55770898 Rho GTPase activating protein 25 isoform a [Homo
sapiens]
Length = 645
Score = 54.3 bits (129), Expect = 5e-07
Identities = 41/164 (25%), Positives = 76/164 (46%), Gaps = 13/164 (7%)
Query: 731 PLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTSIPETIPGSN--HSVA 788
P VP + + + ++ ++E +F+ PG ++Q+ D D + H+VA
Sbjct: 173 PHLVPILVEKCAEFILEHGRNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVA 232
Query: 789 EALLIFLEALPEPVICYELYQRCL--------DSAYDPRICRQVISQLPRCHRNVFRYLM 840
L ++L LPEPV+ + Y+ L D A + + +S LPR + ++ Y+
Sbjct: 233 SLLKLYLRDLPEPVVPWSQYEGFLLCGQLTNADEAKAQQELMKQLSILPRDNYSLLSYIC 292
Query: 841 AFLRELLKFSEYNSVNANMIATLFTSLLLR---PPPNLMARQTP 881
FL E+ N ++ + +AT+ L+R P ++ R TP
Sbjct: 293 RFLHEIQLNCAVNKMSVDNLATVIGVNLIRSKVEDPAVIMRGTP 336
>gi|7661882 Rho GTPase activating protein 25 isoform b [Homo
sapiens]
Length = 638
Score = 54.3 bits (129), Expect = 5e-07
Identities = 41/164 (25%), Positives = 76/164 (46%), Gaps = 13/164 (7%)
Query: 731 PLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTSIPETIPGSN--HSVA 788
P VP + + + ++ ++E +F+ PG ++Q+ D D + H+VA
Sbjct: 166 PHLVPILVEKCAEFILEHGRNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVA 225
Query: 789 EALLIFLEALPEPVICYELYQRCL--------DSAYDPRICRQVISQLPRCHRNVFRYLM 840
L ++L LPEPV+ + Y+ L D A + + +S LPR + ++ Y+
Sbjct: 226 SLLKLYLRDLPEPVVPWSQYEGFLLCGQLTNADEAKAQQELMKQLSILPRDNYSLLSYIC 285
Query: 841 AFLRELLKFSEYNSVNANMIATLFTSLLLR---PPPNLMARQTP 881
FL E+ N ++ + +AT+ L+R P ++ R TP
Sbjct: 286 RFLHEIQLNCAVNKMSVDNLATVIGVNLIRSKVEDPAVIMRGTP 329
>gi|134304853 PTPL1-associated RhoGAP 1 [Homo sapiens]
Length = 1261
Score = 53.5 bits (127), Expect = 9e-07
Identities = 39/205 (19%), Positives = 89/205 (43%), Gaps = 37/205 (18%)
Query: 727 ASERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTS--IPETIPGSN 784
A + P +P + + + A + +++ G + + +++ L+ + + S+
Sbjct: 677 AKKEPDGIPFILKICASEIENRALCLQGIYRVCGNKIKTEKLCQALENGMHLVDISEFSS 736
Query: 785 HSVAEALLIFLEALPEPVICYELYQRCLDSAYD--------------------PRIC--- 821
H + + L ++L LPEP I + LY+ +D A + P +C
Sbjct: 737 HDICDVLKLYLRQLPEPFILFRLYKEFIDLAKEIQHVNEEQETKKNSLEDKKWPNMCIEI 796
Query: 822 -------RQVISQLPRCHRNVFRYLMAFLRELLKFSEYNSVNANMIATLFTSLLLRPPP- 873
+ ++ QLP + N +L+ L+ ++ +E N +N+ + +F L+RP P
Sbjct: 797 NRILLKSKDLLRQLPASNFNSLHFLIVHLKRVVDHAEENKMNSKNLGVIFGPSLIRPRPT 856
Query: 874 ----NLMARQTPSDRQRAIQFLLGF 894
+ + S++ R ++FL+ +
Sbjct: 857 TAPITISSLAEYSNQARLVEFLITY 881
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,191,643
Number of Sequences: 37866
Number of extensions: 1711138
Number of successful extensions: 4795
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 48
Number of HSP's successfully gapped in prelim test: 58
Number of HSP's that attempted gapping in prelim test: 4600
Number of HSP's gapped (non-prelim): 149
length of query: 901
length of database: 18,247,518
effective HSP length: 111
effective length of query: 790
effective length of database: 14,044,392
effective search space: 11095069680
effective search space used: 11095069680
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.