Search of human proteins with 13259514

Search of human proteins with 13259514

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|13259514 dynactin 3 isoform 2 [Homo sapiens]
         (176 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|13259514 dynactin 3 isoform 2 [Homo sapiens]                       347   3e-96
gi|6005745 dynactin 3 isoform 1 [Homo sapiens]                        266   7e-72
gi|22748877 basic helix-loop-helix domain containing, class B, 5...    33   0.13 
gi|57529222 basic helix-loop-helix domain containing, class B, 4...    31   0.49 
gi|109148552 keratin 3 [Homo sapiens]                                  31   0.49 
gi|209862789 microtubule associated monoxygenase, calponin and L...    31   0.63 
gi|110630018 eukaryotic translation initiation factor 4 gamma, 2...    30   1.4  
gi|4503539 eukaryotic translation initiation factor 4 gamma, 2 i...    30   1.4  
gi|4507467 transforming growth factor, beta-induced, 68kDa precu...    29   1.8  
gi|28195388 RAB11 family interacting protein 4 (class II) [Homo ...    29   1.8  
gi|28626521 zinc finger, NFX1-type containing 1 [Homo sapiens]         28   4.1  
gi|4504897 karyopherin alpha 2 [Homo sapiens]                          28   5.4  
gi|156151413 MUS81 endonuclease homolog [Homo sapiens]                 27   7.0  
gi|7662230 ring finger protein 40 [Homo sapiens]                       27   7.0  
gi|12711676 UPF3 regulator of nonsense transcripts homolog A iso...    27   7.0  
gi|18375525 UPF3 regulator of nonsense transcripts homolog A iso...    27   7.0  
gi|38570142 membrane protein, palmitoylated 5 [Homo sapiens]           27   9.2  
gi|29789060 hypothetical protein LOC9847 [Homo sapiens]                27   9.2  

>gi|13259514 dynactin 3 isoform 2 [Homo sapiens]
          Length = 176

 Score =  347 bits (890), Expect = 3e-96
 Identities = 176/176 (100%), Positives = 176/176 (100%)

Query: 1   MAGLTDLQRLQARVEELERWVYGPGGARGSRKVADGLVKVQVALGNISSKRERVKILYKK 60
           MAGLTDLQRLQARVEELERWVYGPGGARGSRKVADGLVKVQVALGNISSKRERVKILYKK
Sbjct: 1   MAGLTDLQRLQARVEELERWVYGPGGARGSRKVADGLVKVQVALGNISSKRERVKILYKK 60

Query: 61  IEDLIKYLDPEYIDRIAIPDASKLQFILAEEQFILSQVALLEQVNALVPMLDSAHIKAVP 120
           IEDLIKYLDPEYIDRIAIPDASKLQFILAEEQFILSQVALLEQVNALVPMLDSAHIKAVP
Sbjct: 61  IEDLIKYLDPEYIDRIAIPDASKLQFILAEEQFILSQVALLEQVNALVPMLDSAHIKAVP 120

Query: 121 EHAARLQRLAQIHIQQQAPWGVGVRDEAGSLVEDVGFAQFLSVLHFGPTGPVCGNH 176
           EHAARLQRLAQIHIQQQAPWGVGVRDEAGSLVEDVGFAQFLSVLHFGPTGPVCGNH
Sbjct: 121 EHAARLQRLAQIHIQQQAPWGVGVRDEAGSLVEDVGFAQFLSVLHFGPTGPVCGNH 176


>gi|6005745 dynactin 3 isoform 1 [Homo sapiens]
          Length = 186

 Score =  266 bits (680), Expect = 7e-72
 Identities = 141/154 (91%), Positives = 147/154 (95%), Gaps = 1/154 (0%)

Query: 1   MAGLTDLQRLQARVEELERWVYGPGGARGSRKVADGLVKVQVALGNISSKRERVKILYKK 60
           MAGLTDLQRLQARVEELERWVYGPGGARGSRKVADGLVKVQVALGNISSKRERVKILYKK
Sbjct: 1   MAGLTDLQRLQARVEELERWVYGPGGARGSRKVADGLVKVQVALGNISSKRERVKILYKK 60

Query: 61  IEDLIKYLDPEYIDRIAIPDASKLQFILAEEQFILSQVALLEQVNALVPMLDSAHIKAVP 120
           IEDLIKYLDPEYIDRIAIPDASKLQFILAEEQFILSQVALLEQVNALVPMLDSAHIKAVP
Sbjct: 61  IEDLIKYLDPEYIDRIAIPDASKLQFILAEEQFILSQVALLEQVNALVPMLDSAHIKAVP 120

Query: 121 EHAARLQRLAQIHIQQQAPWGVGVRDEAGSLVED 154
           EHAARLQRLAQIHIQQQ    V + +E+ +L+E+
Sbjct: 121 EHAARLQRLAQIHIQQQDQC-VEITEESKALLEE 153


>gi|22748877 basic helix-loop-helix domain containing, class B, 5
           [Homo sapiens]
          Length = 381

 Score = 33.1 bits (74), Expect = 0.13
 Identities = 32/119 (26%), Positives = 50/119 (42%), Gaps = 13/119 (10%)

Query: 23  GPGGARGSRKVADGLVKVQVALGNISSKRERVKILYKKIEDLIKYLDP-----EYIDRIA 77
           G GG+  S   +    K Q AL    + RER     +++ DL   LD       Y    +
Sbjct: 222 GSGGSSSSSSSSSKKSKEQKALRLNINARER-----RRMHDLNDALDELRAVIPYAHSPS 276

Query: 78  IPDASKLQFILAEEQFILSQVALLEQVNALVPMLDSAH---IKAVPEHAARLQRLAQIH 133
           +   SK+  +L  + +IL Q   LE++  LV  L+        ++P  AA     A +H
Sbjct: 277 VRKLSKIATLLLAKNYILMQAQALEEMRRLVAYLNQGQAISAASLPSSAAAAAAAAALH 335


>gi|57529222 basic helix-loop-helix domain containing, class B, 4
           [Homo sapiens]
          Length = 225

 Score = 31.2 bits (69), Expect = 0.49
 Identities = 26/109 (23%), Positives = 49/109 (44%), Gaps = 4/109 (3%)

Query: 23  GPGGARGSRKVADGLVKVQVALGNISSKRERVKILYKKIEDLIKYLDPEYIDRIAIPDAS 82
           GPG A   R+       +++++   + +R R+  L   ++ L   +   Y    ++   S
Sbjct: 84  GPGSAADGRRRPREQRSLRLSIN--ARERRRMHDLNDALDGLRAVIP--YAHSPSVRKLS 139

Query: 83  KLQFILAEEQFILSQVALLEQVNALVPMLDSAHIKAVPEHAARLQRLAQ 131
           K+  +L  + +IL Q   L+++  LV  L+     A P +AA L    Q
Sbjct: 140 KIATLLLAKNYILMQAQALDEMRRLVAFLNQGQGLAAPVNAAPLTPFGQ 188


>gi|109148552 keratin 3 [Homo sapiens]
          Length = 628

 Score = 31.2 bits (69), Expect = 0.49
 Identities = 20/72 (27%), Positives = 39/72 (54%), Gaps = 3/72 (4%)

Query: 44  LGNISSKRERVKILYKKIEDLIKYLDPEYIDRIAIPDASKLQFILAE---EQFILSQVAL 100
           L NI  +R R+    K +EDL++    +Y D I    A++ +F+  +   +   +++V L
Sbjct: 262 LDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRTAAENEFVTLKKDVDSAYMNKVEL 321

Query: 101 LEQVNALVPMLD 112
             +V+AL+  +D
Sbjct: 322 QAKVDALIDEID 333


>gi|209862789 microtubule associated monoxygenase, calponin and LIM
            domain containing 3 isoform 1 [Homo sapiens]
          Length = 2002

 Score = 30.8 bits (68), Expect = 0.63
 Identities = 18/59 (30%), Positives = 37/59 (62%), Gaps = 1/59 (1%)

Query: 60   KIEDLIKYLDPEYIDRIAIPDASKLQFILAEEQFILSQ-VALLEQVNALVPMLDSAHIK 117
            ++ED    L  E  +R+A+ D  K +  L+EE+ IL++ + ++EQ ++LV +L+   ++
Sbjct: 1922 ELEDRQSRLQQELRERMAVEDHLKTEEELSEEKQILNEMLEVVEQRDSLVALLEEQRLR 1980


>gi|110630018 eukaryotic translation initiation factor 4 gamma, 2
           isoform 2 [Homo sapiens]
          Length = 869

 Score = 29.6 bits (65), Expect = 1.4
 Identities = 16/59 (27%), Positives = 32/59 (54%), Gaps = 4/59 (6%)

Query: 43  ALGNISSKRERVKILYKKIEDLIKYLDPEYIDRIAIPDASKLQFILAEEQFILSQVALL 101
           A  N ++++ER   +++K+  ++  L PE  D++ +    +L  +  E + IL  V LL
Sbjct: 63  AANNSANEKERHDAIFRKVRGILNKLTPEKFDKLCL----ELLNVGVESKLILKGVILL 117


>gi|4503539 eukaryotic translation initiation factor 4 gamma, 2
           isoform 1 [Homo sapiens]
          Length = 907

 Score = 29.6 bits (65), Expect = 1.4
 Identities = 16/59 (27%), Positives = 32/59 (54%), Gaps = 4/59 (6%)

Query: 43  ALGNISSKRERVKILYKKIEDLIKYLDPEYIDRIAIPDASKLQFILAEEQFILSQVALL 101
           A  N ++++ER   +++K+  ++  L PE  D++ +    +L  +  E + IL  V LL
Sbjct: 63  AANNSANEKERHDAIFRKVRGILNKLTPEKFDKLCL----ELLNVGVESKLILKGVILL 117


>gi|4507467 transforming growth factor, beta-induced, 68kDa
           precursor [Homo sapiens]
          Length = 683

 Score = 29.3 bits (64), Expect = 1.8
 Identities = 21/74 (28%), Positives = 31/74 (41%), Gaps = 11/74 (14%)

Query: 72  YIDRIAIPDASKLQFILAEEQFILSQVALLEQVN-----------ALVPMLDSAHIKAVP 120
           YID + IPD++K  F LA E  + + + L  Q              L+  L+S      P
Sbjct: 366 YIDELLIPDSAKTLFELAAESDVSTAIDLFRQAGLGNHLSGSERLTLLAPLNSVFKDGTP 425

Query: 121 EHAARLQRLAQIHI 134
              A  + L + HI
Sbjct: 426 PIDAHTRNLLRNHI 439


>gi|28195388 RAB11 family interacting protein 4 (class II) [Homo
           sapiens]
          Length = 637

 Score = 29.3 bits (64), Expect = 1.8
 Identities = 15/49 (30%), Positives = 25/49 (51%)

Query: 59  KKIEDLIKYLDPEYIDRIAIPDASKLQFILAEEQFILSQVALLEQVNAL 107
           +++E L+KYLDP  + RI   D  +  F +   + +L  V  +E    L
Sbjct: 52  EEVEKLVKYLDPNDLGRINFKDFCRGVFAMKGCEELLKDVLSVESAGTL 100


>gi|28626521 zinc finger, NFX1-type containing 1 [Homo sapiens]
          Length = 1918

 Score = 28.1 bits (61), Expect = 4.1
 Identities = 27/99 (27%), Positives = 46/99 (46%), Gaps = 13/99 (13%)

Query: 39   KVQVALGNISSKRERVKILYKKIEDLIKYLDPEYIDRIAIPDASKLQFILAEEQFILSQV 98
            K+Q + G I++ +ER+K L ++ + L+  L PE        D   L+  LA++   +  +
Sbjct: 1649 KIQGSAGEIATSQERLKALLER-KSLLHQLLPE--------DFLMLKEKLAQKNLSVKDL 1699

Query: 99   ALLEQ----VNALVPMLDSAHIKAVPEHAARLQRLAQIH 133
             L+E      + L  + DS     V E      RL Q+H
Sbjct: 1700 GLVENYISFYDHLASLWDSLKKMHVLEEKRVRTRLEQVH 1738


>gi|4504897 karyopherin alpha 2 [Homo sapiens]
          Length = 529

 Score = 27.7 bits (60), Expect = 5.4
 Identities = 31/115 (26%), Positives = 51/115 (44%), Gaps = 20/115 (17%)

Query: 61  IEDLIKY-LDPEYIDRIAIPDASKLQFILAEEQFILSQVA--LLEQVNALVPMLDSAHIK 117
           I+++I+  L P+++  +   D S +QF   E  + L+ +A    EQ  A+V   D   I 
Sbjct: 112 IDNIIRAGLIPKFVSFLGRTDCSPIQF---ESAWALTNIASGTSEQTKAVV---DGGAIP 165

Query: 118 AVPEHAARLQRLAQIHIQQQAPWGVGVRDEAGSLVEDVGFAQFLSVLHFGPTGPV 172
           A       L      HI +QA W +G     GS+  D+       V+ +G   P+
Sbjct: 166 AF----ISLLASPHAHISEQAVWALGNIAGDGSVFRDL-------VIKYGAVDPL 209


>gi|156151413 MUS81 endonuclease homolog [Homo sapiens]
          Length = 551

 Score = 27.3 bits (59), Expect = 7.0
 Identities = 23/105 (21%), Positives = 45/105 (42%), Gaps = 16/105 (15%)

Query: 67  YLDPEY--IDRIAIPDASKLQFILAEEQ---FILSQVALLEQVNALVPMLDSAHIKAVPE 121
           YL  E+  +  +++P+++ LQ +   +    F + + A +++  A + +L          
Sbjct: 366 YLVEEHGSVHNLSLPESTLLQAVTNTQVIDGFFVKRTADIKESAAYLALLTRG------- 418

Query: 122 HAARLQRLAQIHIQQQAPWGVGVRDEAGSLVEDVGFAQFLSVLHF 166
               LQRL Q H  +  PWG     E+G++         L+   F
Sbjct: 419 ----LQRLYQGHTLRSRPWGTPGNPESGAMTSPNPLCSLLTFSDF 459


>gi|7662230 ring finger protein 40 [Homo sapiens]
          Length = 1001

 Score = 27.3 bits (59), Expect = 7.0
 Identities = 25/109 (22%), Positives = 49/109 (44%), Gaps = 11/109 (10%)

Query: 9   RLQARVEELERWVYGPGGARGSRKVADGLV--------KVQVALGNISSKRERVKILYKK 60
           RLQ RVEEL + VY  G +    + A            ++Q     +  K  R+ + Y +
Sbjct: 201 RLQRRVEELCQRVYSRGDSEPLSEAAQAHTRELGRENRRLQDLATQLQEKHHRISLEYSE 260

Query: 61  IEDLIKYLDPEYID-RIAIPDAS-KLQFILAEEQFILSQVA-LLEQVNA 106
           ++D +   + + ++    + D    ++ +   EQ +   +A  LEQ+N+
Sbjct: 261 LQDKVTSAETKVLEMETTVEDLQWDIEKLRKREQKLNKHLAEALEQLNS 309


>gi|12711676 UPF3 regulator of nonsense transcripts homolog A
           isoform hUpf3p [Homo sapiens]
          Length = 476

 Score = 27.3 bits (59), Expect = 7.0
 Identities = 12/28 (42%), Positives = 16/28 (57%)

Query: 8   QRLQARVEELERWVYGPGGARGSRKVAD 35
           +RL  R E+ +RW  GPG  RG +   D
Sbjct: 376 ERLSRRSEDEQRWGKGPGQDRGKKGSQD 403


>gi|18375525 UPF3 regulator of nonsense transcripts homolog A
           isoform hUpf3pdelta [Homo sapiens]
          Length = 443

 Score = 27.3 bits (59), Expect = 7.0
 Identities = 12/28 (42%), Positives = 16/28 (57%)

Query: 8   QRLQARVEELERWVYGPGGARGSRKVAD 35
           +RL  R E+ +RW  GPG  RG +   D
Sbjct: 343 ERLSRRSEDEQRWGKGPGQDRGKKGSQD 370


>gi|38570142 membrane protein, palmitoylated 5 [Homo sapiens]
          Length = 675

 Score = 26.9 bits (58), Expect = 9.2
 Identities = 13/62 (20%), Positives = 30/62 (48%)

Query: 91  EQFILSQVALLEQVNALVPMLDSAHIKAVPEHAARLQRLAQIHIQQQAPWGVGVRDEAGS 150
           +  +L+   + EQ   L P+ D    +++ ++     ++ +I   +  P G  VR+E  S
Sbjct: 218 QALLLAHDKVAEQEMQLEPITDERVYESIGQYGGETVKIVRIEKARDIPLGATVRNEMDS 277

Query: 151 LV 152
           ++
Sbjct: 278 VI 279


>gi|29789060 hypothetical protein LOC9847 [Homo sapiens]
          Length = 1000

 Score = 26.9 bits (58), Expect = 9.2
 Identities = 15/32 (46%), Positives = 20/32 (62%), Gaps = 2/32 (6%)

Query: 53  RVKILYKKIEDLIKYLDPEY--IDRIAIPDAS 82
           R  I++  +E+L+   DPEY  IDRI  P AS
Sbjct: 157 RAVIIHGFVEELVVNEDPEYQWIDRIRTPRAS 188


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.138    0.399 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,259,414
Number of Sequences: 37866
Number of extensions: 240953
Number of successful extensions: 812
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 802
Number of HSP's gapped (non-prelim): 18
length of query: 176
length of database: 18,247,518
effective HSP length: 95
effective length of query: 81
effective length of database: 14,650,248
effective search space: 1186670088
effective search space used: 1186670088
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.