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Search of human proteins with 4759344
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4759344 centromere/kinetochore protein zw10 [Homo sapiens]
(779 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4759344 centromere/kinetochore protein zw10 [Homo sapiens] 1531 0.0
gi|71061468 centromere protein E [Homo sapiens] 48 4e-05
gi|55770834 centromere protein F [Homo sapiens] 44 4e-04
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 44 8e-04
gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens] 42 0.003
gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens] 42 0.003
gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens] 42 0.003
gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens] 42 0.003
gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens] 42 0.003
gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens] 42 0.003
gi|56550047 uveal autoantigen with coiled-coil domains and ankyr... 41 0.004
gi|59850762 uveal autoantigen with coiled-coil domains and ankyr... 41 0.004
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 39 0.018
gi|215982791 myosin VA isoform 1 [Homo sapiens] 39 0.024
gi|4502443 dystonin isoform 1e precursor [Homo sapiens] 39 0.024
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens] 39 0.024
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 38 0.032
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 38 0.032
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 38 0.041
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 38 0.041
gi|209969819 hypothetical protein LOC253143 [Homo sapiens] 37 0.054
gi|62548856 BCL2-associated athanogene 5 isoform a [Homo sapiens] 37 0.054
gi|6631077 BCL2-associated athanogene 5 isoform b [Homo sapiens] 37 0.054
gi|62548854 BCL2-associated athanogene 5 isoform b [Homo sapiens] 37 0.054
gi|215982794 myosin VA isoform 2 [Homo sapiens] 37 0.070
gi|19923899 coiled-coil domain containing 45 [Homo sapiens] 37 0.092
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 36 0.12
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 36 0.16
gi|55749708 outer dense fiber of sperm tails 2-like isoform b [H... 36 0.16
gi|55749696 outer dense fiber of sperm tails 2-like isoform a [H... 36 0.16
>gi|4759344 centromere/kinetochore protein zw10 [Homo sapiens]
Length = 779
Score = 1531 bits (3965), Expect = 0.0
Identities = 779/779 (100%), Positives = 779/779 (100%)
Query: 1 MASFVTEVLAHSGRLEKEDLGTRISRLTRRVEEIKGEVCNMISKKYSEFLPSMQSAQGLI 60
MASFVTEVLAHSGRLEKEDLGTRISRLTRRVEEIKGEVCNMISKKYSEFLPSMQSAQGLI
Sbjct: 1 MASFVTEVLAHSGRLEKEDLGTRISRLTRRVEEIKGEVCNMISKKYSEFLPSMQSAQGLI 60
Query: 61 TQVDKLSEDIDLLKSRIESEVRRDLHVSTGEFTDLKQQLERDSVVLSLLKQLQEFSTAIE 120
TQVDKLSEDIDLLKSRIESEVRRDLHVSTGEFTDLKQQLERDSVVLSLLKQLQEFSTAIE
Sbjct: 61 TQVDKLSEDIDLLKSRIESEVRRDLHVSTGEFTDLKQQLERDSVVLSLLKQLQEFSTAIE 120
Query: 121 EYNCALTEKKYVTGAQRLEEAQKCLKLLKSRKCFDLKILKSLSMELTIQKQNILYHLGEE 180
EYNCALTEKKYVTGAQRLEEAQKCLKLLKSRKCFDLKILKSLSMELTIQKQNILYHLGEE
Sbjct: 121 EYNCALTEKKYVTGAQRLEEAQKCLKLLKSRKCFDLKILKSLSMELTIQKQNILYHLGEE 180
Query: 181 WQKLIVWKFPPSKDTSSLESYLQTELHLYTEQSHKEEKTPMPPISSVLLAFSVLGELHSK 240
WQKLIVWKFPPSKDTSSLESYLQTELHLYTEQSHKEEKTPMPPISSVLLAFSVLGELHSK
Sbjct: 181 WQKLIVWKFPPSKDTSSLESYLQTELHLYTEQSHKEEKTPMPPISSVLLAFSVLGELHSK 240
Query: 241 LKSFGQMLLKYILRPLASCPSLHAVIESQPNIVIIRFESIMTNLEYPSPSEVFTKIRLVL 300
LKSFGQMLLKYILRPLASCPSLHAVIESQPNIVIIRFESIMTNLEYPSPSEVFTKIRLVL
Sbjct: 241 LKSFGQMLLKYILRPLASCPSLHAVIESQPNIVIIRFESIMTNLEYPSPSEVFTKIRLVL 300
Query: 301 EVLQKQLLDLPLDTDLENEKTSTVPLAEMLGDMIWEDLSECLIKNCLVYSIPTNSSKLQQ 360
EVLQKQLLDLPLDTDLENEKTSTVPLAEMLGDMIWEDLSECLIKNCLVYSIPTNSSKLQQ
Sbjct: 301 EVLQKQLLDLPLDTDLENEKTSTVPLAEMLGDMIWEDLSECLIKNCLVYSIPTNSSKLQQ 360
Query: 361 YEEIIQSTEEFENALKEMRFLKGDTTDLLKYARNINSHFANKKCQDVIVAARNLMTSEIH 420
YEEIIQSTEEFENALKEMRFLKGDTTDLLKYARNINSHFANKKCQDVIVAARNLMTSEIH
Sbjct: 361 YEEIIQSTEEFENALKEMRFLKGDTTDLLKYARNINSHFANKKCQDVIVAARNLMTSEIH 420
Query: 421 NTVKIIPDSKINVPELPTPDEDNKLEVQKVSNTQYHEVMNLEPENTLDQHSFSLPTCRIS 480
NTVKIIPDSKINVPELPTPDEDNKLEVQKVSNTQYHEVMNLEPENTLDQHSFSLPTCRIS
Sbjct: 421 NTVKIIPDSKINVPELPTPDEDNKLEVQKVSNTQYHEVMNLEPENTLDQHSFSLPTCRIS 480
Query: 481 ESVKKLMELAYQTLLEATTSSDQCAVQLFYSVRNIFHLFHDVVPTYHKENLQKLPQLAAI 540
ESVKKLMELAYQTLLEATTSSDQCAVQLFYSVRNIFHLFHDVVPTYHKENLQKLPQLAAI
Sbjct: 481 ESVKKLMELAYQTLLEATTSSDQCAVQLFYSVRNIFHLFHDVVPTYHKENLQKLPQLAAI 540
Query: 541 HHNNCMYIAHHLLTLGHQFRLRLAPILCDGTATFVDLVPGFRRLGTECFLAQMRAQKGEL 600
HHNNCMYIAHHLLTLGHQFRLRLAPILCDGTATFVDLVPGFRRLGTECFLAQMRAQKGEL
Sbjct: 541 HHNNCMYIAHHLLTLGHQFRLRLAPILCDGTATFVDLVPGFRRLGTECFLAQMRAQKGEL 600
Query: 601 LERLSSARNFSNMDDEENYSAASKAVRQVLHQLKRLGIVWQDVLPVNIYCKAMGTLLNTA 660
LERLSSARNFSNMDDEENYSAASKAVRQVLHQLKRLGIVWQDVLPVNIYCKAMGTLLNTA
Sbjct: 601 LERLSSARNFSNMDDEENYSAASKAVRQVLHQLKRLGIVWQDVLPVNIYCKAMGTLLNTA 660
Query: 661 ISEVIGKITALEDISTEDGDRLYSLCKTVMDEGPQVFAPLSEESKNKKYQEEVPVYVPKW 720
ISEVIGKITALEDISTEDGDRLYSLCKTVMDEGPQVFAPLSEESKNKKYQEEVPVYVPKW
Sbjct: 661 ISEVIGKITALEDISTEDGDRLYSLCKTVMDEGPQVFAPLSEESKNKKYQEEVPVYVPKW 720
Query: 721 MPFKELMMMLQASLQEIGDRWADGKGPLAAAFSSSEVKALIRALFQNTERRAAALAKIK 779
MPFKELMMMLQASLQEIGDRWADGKGPLAAAFSSSEVKALIRALFQNTERRAAALAKIK
Sbjct: 721 MPFKELMMMLQASLQEIGDRWADGKGPLAAAFSSSEVKALIRALFQNTERRAAALAKIK 779
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 47.8 bits (112), Expect = 4e-05
Identities = 114/535 (21%), Positives = 215/535 (40%), Gaps = 97/535 (18%)
Query: 16 EKEDLGTRISRLTRRVEEIKGEVCNMISKKYSEFLPSMQSAQGLITQVDKLSEDIDLLKS 75
EK+DL L +++K ++ + ++ + + + + + + + E I+ LKS
Sbjct: 930 EKDDLKQLQESLQIERDQLKSDIHDTVNMN----IDTQEQLRNALESLKQHQETINTLKS 985
Query: 76 RIESEVRRDLHV--STGEFTDLKQQ--LERDSVVLSLLKQLQEFSTAIEEYNCALTEKKY 131
+I EV R+LH+ +TGE D QQ + D K Q + +++ ++K
Sbjct: 986 KISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKI 1045
Query: 132 VTGAQRLEEAQKCLKLLKSRKCFDLKILKSLSMELTIQKQNILYHLGEEWQKLIVWKFPP 191
+ Q E Q+ L+ + + K LK ++E+TI+ Q L LG+E +K
Sbjct: 1046 FSLIQEKNELQQMLESVIAEK-EQLKTDLKENIEMTIENQEELRLLGDELKK-------- 1096
Query: 192 SKDTSSLESYLQTELHLYTEQSHKEEKTPMPPISSVLLAFSVLGELHSKLKSFGQMLLKY 251
Q E+ + E++H +K + L E+ KLK Q L
Sbjct: 1097 -----------QQEI-VAQEKNHAIKKE-----GELSRTCDRLAEVEEKLKEKSQQLQ-- 1137
Query: 252 ILRPLASCPSLHAVIESQPNIVIIRFESIMTNLEYPSPSEVFTKIRLVLEVLQKQLLDLP 311
E Q ++ ++ E SE+ KI +E L+ +L +
Sbjct: 1138 ---------------EKQQQLLNVQEEM----------SEMQKKIN-EIENLKNELKNKE 1171
Query: 312 LDTDLENEKTSTVPLAEMLGDMIWEDLSECLIKNCLVYSIPTNSSKLQQYEEIIQS-TEE 370
L LE+ +T + LA+ L + E V SI L++ ++ ++ +
Sbjct: 1172 L--TLEHMETERLELAQKLNENYEE-----------VKSITKERKVLKELQKSFETERDH 1218
Query: 371 FENALKEMRFLKGDTTDLLKYARNINSHFANKKCQDVIVAARNLM---TSEIHNTVKIIP 427
++E+ T + LK A H K+ Q+ I R + T++I NT +
Sbjct: 1219 LRGYIREIEATGLQTKEELKIA-----HIHLKEHQETIDELRRSVSEKTAQIINTQDLEK 1273
Query: 428 DSKINVPELPTPDEDNKL--EVQKVSNTQYHEVMN---LEPENTLDQHSFSLPTCRISE- 481
E+P E+ +L V++VS TQ E MN L E + + S +L +
Sbjct: 1274 SHTKLQEEIPVLHEEQELLPNVKEVSETQ--ETMNELELLTEQSTTKDSTTLARIEMERL 1331
Query: 482 SVKKLMELAYQTLLEATTSSDQCAVQLFYSVRNIFHLFHDVVPTYHKENLQKLPQ 536
+ + + + + + T D +++ + HD + + +E L K+ +
Sbjct: 1332 RLNEKFQESQEEIKSLTKERDN-----LKTIKEALEVKHDQLKEHIRETLAKIQE 1381
Score = 34.3 bits (77), Expect = 0.46
Identities = 44/206 (21%), Positives = 96/206 (46%), Gaps = 25/206 (12%)
Query: 16 EKEDLGTRISRLTRRVEEIKGEVCNMISKK---YSEFLPSMQSAQGLITQVDKLSEDIDL 72
E + L + + RL + +++ E+ + S+K +SE + QGL+ ++ K +D+
Sbjct: 748 ELKSLPSEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLAT 807
Query: 73 LKSRIESEVR-----RDLHVS-TGEFTDLKQQLER-DSVVLSLLKQLQEFSTAIE----- 120
+S +S + + LH+ ++ + ++ ER + +++L K+ Q+F +++
Sbjct: 808 TQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTE 867
Query: 121 -EYNCALTEKKYVTGAQRLEEAQKCLKLLKSRKCFDLKILKSLSMELTIQKQNILYHLGE 179
Y ++K +RL E ++ + L++R L+++ E T+ + + L E
Sbjct: 868 LSYKTQELQEKTREVQERLNEMEQLKEQLENRD----STLQTVEREKTLITEKLQQTL-E 922
Query: 180 EWQKLIVWKFPPSKDTSSLESYLQTE 205
E + L K D L+ LQ E
Sbjct: 923 EVKTLTQEK----DDLKQLQESLQIE 944
Score = 33.5 bits (75), Expect = 0.78
Identities = 94/456 (20%), Positives = 192/456 (42%), Gaps = 87/456 (19%)
Query: 14 RLEKEDLGTRISRLTRRVEEIKGEVCNMISKKYSEFLPSMQSAQGLITQVDKLSEDI-DL 72
R+E E LG L++R++E E+ ++ +K + L +Q L ++ D+L E+I ++
Sbjct: 1418 RIEIEMLG-----LSKRLQESHDEMKSVAKEK--DDLQRLQEV--LQSESDQLKENIKEI 1468
Query: 73 LKSRIESEVRRDL-HVSTGEFTDLKQQL-----ERDSVVLSLLKQLQEFSTAIEEYNCAL 126
+ +E+E + H E + +L E+++ + ++ KQL+ + ++ +
Sbjct: 1469 VAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEI 1528
Query: 127 TEKKYVTGAQRLEEAQKCLKLLKS----RKCFD--LKILKSLSMELTIQKQNILYHLGEE 180
EK+ +++ E Q+ + LK RK D L+ ++S +ELT N L EE
Sbjct: 1529 YEKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIESKMLELT----NRLQESQEE 1584
Query: 181 WQKLIVWKFPPSKDTSSLESYLQTELHLYTEQSHKEEKTPMPPISSVLLAFSVLGELHSK 240
Q +I K E + + L E+ +E T E+ +K
Sbjct: 1585 IQIMIKEK----------EEMKRVQEALQIERDQLKENTK---------------EIVAK 1619
Query: 241 LKSFGQMLLKYILRPLASCPSLHAVIESQPNIVII-----RFESIMTNLEYPSPSEVFTK 295
+K + +++ + AV E+Q + I +FE+ NLE + T+
Sbjct: 1620 MKESQEKEYQFL--------KMTAVNETQEKMCEIEHLKEQFETQKLNLE-----NIETE 1666
Query: 296 IRLVLEVLQKQLLDLPLDTDLENEKTSTVPLAEMLGDMIWEDLSECLIKNC-LVYSIPTN 354
+ ++L + L ++ T ++ S ++ D + E+L E + ++ +
Sbjct: 1667 NIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIV 1726
Query: 355 SSKLQQYEEII--------QSTEEFENALKEMRF----LKGDTTDLLKYARNINSHFANK 402
L++++E I + T E N K++ LK + + R + H K
Sbjct: 1727 HMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHL--K 1784
Query: 403 KCQDVIVAARNLM---TSEIHNTVKIIPDSKINVPE 435
+ Q+ I R ++ T ++ N K + +S + E
Sbjct: 1785 EQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQE 1820
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 44.3 bits (103), Expect = 4e-04
Identities = 135/673 (20%), Positives = 256/673 (38%), Gaps = 124/673 (18%)
Query: 10 AHSGRLEKEDLGTRISRLTRRVEEIKGEVCNMISKKYSEFLPSMQSAQGLITQVDKLSED 69
A + + E E L T+I + R ++ + ++ + S+K +Q QG ++++DKL
Sbjct: 2177 AENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEK-ENLTKQIQEKQGQLSELDKLLSS 2235
Query: 70 I-DLLKSRIESEVRRDLHVSTGEFTDLKQQLERDSVVLSL-----------------LKQ 111
LL+ + ++E++ T Q E + V +L +++
Sbjct: 2236 FKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEE 2295
Query: 112 LQEFSTAIEEYNCALT--EKKYVTGAQRLEEAQKCLKLLKSRKCFDLKILKSLSMELTIQ 169
+ +IE+ L EKK + Q+L+E++ LLK R +++L EL I
Sbjct: 2296 EHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGR-------VENLERELEIA 2348
Query: 170 KQNILYHLGEEWQKLIVWKFPPSKDTSSLESYLQTELHLYTEQSHKEEKTPMPPISSVLL 229
+ N + E + +K +S EL + T +S KE T
Sbjct: 2349 RTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLT---------- 2398
Query: 230 AFSVLGELHSKLKSFGQMLLKYILRPLASCPSLHAVIESQPNIVIIRFESIMTNLEYPSP 289
EL + + ++ I+ FE+I+ E
Sbjct: 2399 -----NELQKEQERISEL-----------------------EIINSSFENILQEKE-QEK 2429
Query: 290 SEVFTKIRLVLEVLQKQLLDL-----PLDTDLENEK------TSTVPLAEMLGDMIWEDL 338
++ K +E+LQ QL +L L D E K +S V E+ + + L
Sbjct: 2430 VQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGL 2489
Query: 339 SECLIKNCLVYSIPTNSSKLQQYEEIIQSTEEFENALKEMRFLKGDTTDLLKYARNINSH 398
E KN + + + +Q+ E+ Q E+ + + ++ D L+ +
Sbjct: 2490 DEA--KNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGE 2547
Query: 399 FANKKCQDVIVAARNLMTSEIHNTVKIIPDSK------INVPELPTPDEDNKLEVQKVSN 452
K Q+ + RNL T E+ ++++ + V + + +N+LE+ K+
Sbjct: 2548 HQLWKEQN--LELRNL-TVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDK 2604
Query: 453 TQYHEVMN----LEPENTLDQHSFSLPTCRISESV---KKLMELAYQTLLEATTSSDQCA 505
+ E +N E E + H + T + E + K + Q LLE SS
Sbjct: 2605 MSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQL 2664
Query: 506 VQLFYSVRNIFHLFHDVVPTYHKENLQKLPQLAAIHHNNCMYIAHHLLTLGHQFRLRLAP 565
+L + + HK+ ++K ++ IA + L L H+ +
Sbjct: 2665 KELTLENSEL----KKSLDCMHKDQVEKEGKVRE-------EIAEYQLRL-HEAEKKHQA 2712
Query: 566 ILCDGTATFVDLVPGFRRLGT---ECFLAQMRAQKGELLERLSSARNFSNMDDEENYSAA 622
+L D + + +R T EC + +QK E ++ L S++ E + +
Sbjct: 2713 LLLDTNKQYEVEIQTYREKLTSKEEC----LSSQKLE-IDLLKSSK--------EELNNS 2759
Query: 623 SKAVRQVLHQLKR 635
KA Q+L +LK+
Sbjct: 2760 LKATTQILEELKK 2772
Score = 34.7 bits (78), Expect = 0.35
Identities = 58/209 (27%), Positives = 87/209 (41%), Gaps = 32/209 (15%)
Query: 16 EKEDLGTRISRLTRRVEEIKGEVCNMISK-------KYSEFLPSMQSAQGLITQVDKLSE 68
EKE L L R+ E E N +SK + EF + S Q +V +L
Sbjct: 2064 EKELLVKESESLQARLSESDYEKLN-VSKALEAALVEKGEFALRLSSTQ---EEVHQLRR 2119
Query: 69 DIDLLKSRIESEVRRDLHVS------TGEFTDLKQQLERDSVVLSLLKQLQEFSTAIEEY 122
I+ L+ RIE++ ++ LH++ E LK ++E L + ++ QE E
Sbjct: 2120 GIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAEN 2179
Query: 123 NCALTEKKYVTGAQRLEEAQKCLKLLKSRKCFDLKILKSLSMELTIQKQNILYHLGEEWQ 182
+ A E T ++EE + LK+ + DL L+S LT Q Q L E
Sbjct: 2180 SKAEVE----TLKTQIEEMARSLKVFE----LDLVTLRSEKENLTKQIQEKQGQL-SELD 2230
Query: 183 KLIVWKFPPSKDTSSLESYLQTELHLYTE 211
KL+ S S LE Q E+ + E
Sbjct: 2231 KLL------SSFKSLLEEKEQAEIQIKEE 2253
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 43.5 bits (101), Expect = 8e-04
Identities = 45/180 (25%), Positives = 82/180 (45%), Gaps = 14/180 (7%)
Query: 32 EEIKGEVCNMISKKYSEFLPSMQSAQGLITQVDKLSEDIDL--------LKSRIESEVRR 83
EEI E+ +++ K S+F + + L ++ KL +DI++ L+ ESEV
Sbjct: 1516 EEILKEINKIVAAKDSDFQCLSKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVL- 1574
Query: 84 DLHVSTGEFTDLKQQLERDSVVLSLLKQLQEFSTAIEEYNCALTEKKYVTGAQRLEEAQK 143
L E LK Q+ +++L + + EE + L + V L+EA +
Sbjct: 1575 -LQAKRAELEKLKSQVTSQQQEMAVLDR--QLGHKKEELH--LLQGSMVQAKADLQEALR 1629
Query: 144 CLKLLKSRKCFDLKILKSLSMELTIQKQNILYHLGEEWQKLIVWKFPPSKDTSSLESYLQ 203
+ + KC ++ +KSL EL+ QK + + E +L + K K+ +L+ L+
Sbjct: 1630 LGETEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQLTLIKQEIEKEEENLQVVLR 1689
>gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]
Length = 983
Score = 41.6 bits (96), Expect = 0.003
Identities = 84/396 (21%), Positives = 156/396 (39%), Gaps = 48/396 (12%)
Query: 14 RLEKEDLGTRISRLTRRVEEIKGEVCNMISKKYSEFLPSMQSAQGLITQVDKLSEDIDLL 73
+L + + GT I EE+K C++I E L + + E+I L
Sbjct: 562 KLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKE-------KAFLFEKYQEAQEEIMKL 614
Query: 74 KSRIESEVRRDLHVSTGEFTDLKQQLERDSVVLSLLKQLQEFSTAIEEYNCALTE----- 128
K ++S++ ++ ++ E D+K+ + R ++ L KQ+ E S +E L +
Sbjct: 615 KDTLKSQMTQE---ASDEAEDMKEAMNR--MIDELNKQVSELSQLYKEAQAELEDYRKRK 669
Query: 129 ------KKYVTGAQRLE----------EAQKCLKLLKSRKCFDLKILKSLSMELTIQKQN 172
+Y+ A+ + +A+ L +KS+ L L L + QK+N
Sbjct: 670 SLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKEN 729
Query: 173 ---ILYHLGEEWQKLIVWKFPPSKDTSSLESYLQTELHL-YTEQSHKEEKTPMPPISSVL 228
I HL K K ++ E E+ + E+ EEK M + +
Sbjct: 730 SVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAM---TDAM 786
Query: 229 LAFSVLGELHSKLKSFGQMLLKYILRPLASCPSLHA---VIESQPNIVIIRFESIMTNLE 285
+ S +L S L+S +L + + +H+ I S+ + V E+I T L+
Sbjct: 787 VPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQTLLK 846
Query: 286 YPSP--SEVFTKIRLVLEVLQKQLLDLPLDTDLENEKTSTVPLAEMLGDMIWEDLSECLI 343
+E+ K + E L + + LE +K + + E L+
Sbjct: 847 SKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSL-- 904
Query: 344 KNCLVYSIPTNSSKLQQYEEIIQSTEEFENALKEMR 379
+ L YS ++ + QQ E + Q ++ +N L E +
Sbjct: 905 -SQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECK 939
>gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]
Length = 972
Score = 41.6 bits (96), Expect = 0.003
Identities = 84/396 (21%), Positives = 156/396 (39%), Gaps = 48/396 (12%)
Query: 14 RLEKEDLGTRISRLTRRVEEIKGEVCNMISKKYSEFLPSMQSAQGLITQVDKLSEDIDLL 73
+L + + GT I EE+K C++I E L + + E+I L
Sbjct: 551 KLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKE-------KAFLFEKYQEAQEEIMKL 603
Query: 74 KSRIESEVRRDLHVSTGEFTDLKQQLERDSVVLSLLKQLQEFSTAIEEYNCALTE----- 128
K ++S++ ++ ++ E D+K+ + R ++ L KQ+ E S +E L +
Sbjct: 604 KDTLKSQMTQE---ASDEAEDMKEAMNR--MIDELNKQVSELSQLYKEAQAELEDYRKRK 658
Query: 129 ------KKYVTGAQRLE----------EAQKCLKLLKSRKCFDLKILKSLSMELTIQKQN 172
+Y+ A+ + +A+ L +KS+ L L L + QK+N
Sbjct: 659 SLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKEN 718
Query: 173 ---ILYHLGEEWQKLIVWKFPPSKDTSSLESYLQTELHL-YTEQSHKEEKTPMPPISSVL 228
I HL K K ++ E E+ + E+ EEK M + +
Sbjct: 719 SVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAM---TDAM 775
Query: 229 LAFSVLGELHSKLKSFGQMLLKYILRPLASCPSLHA---VIESQPNIVIIRFESIMTNLE 285
+ S +L S L+S +L + + +H+ I S+ + V E+I T L+
Sbjct: 776 VPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQTLLK 835
Query: 286 YPSP--SEVFTKIRLVLEVLQKQLLDLPLDTDLENEKTSTVPLAEMLGDMIWEDLSECLI 343
+E+ K + E L + + LE +K + + E L+
Sbjct: 836 SKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSL-- 893
Query: 344 KNCLVYSIPTNSSKLQQYEEIIQSTEEFENALKEMR 379
+ L YS ++ + QQ E + Q ++ +N L E +
Sbjct: 894 -SQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECK 928
>gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]
Length = 951
Score = 41.6 bits (96), Expect = 0.003
Identities = 84/396 (21%), Positives = 156/396 (39%), Gaps = 48/396 (12%)
Query: 14 RLEKEDLGTRISRLTRRVEEIKGEVCNMISKKYSEFLPSMQSAQGLITQVDKLSEDIDLL 73
+L + + GT I EE+K C++I E L + + E+I L
Sbjct: 530 KLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKE-------KAFLFEKYQEAQEEIMKL 582
Query: 74 KSRIESEVRRDLHVSTGEFTDLKQQLERDSVVLSLLKQLQEFSTAIEEYNCALTE----- 128
K ++S++ ++ ++ E D+K+ + R ++ L KQ+ E S +E L +
Sbjct: 583 KDTLKSQMTQE---ASDEAEDMKEAMNR--MIDELNKQVSELSQLYKEAQAELEDYRKRK 637
Query: 129 ------KKYVTGAQRLE----------EAQKCLKLLKSRKCFDLKILKSLSMELTIQKQN 172
+Y+ A+ + +A+ L +KS+ L L L + QK+N
Sbjct: 638 SLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKEN 697
Query: 173 ---ILYHLGEEWQKLIVWKFPPSKDTSSLESYLQTELHL-YTEQSHKEEKTPMPPISSVL 228
I HL K K ++ E E+ + E+ EEK M + +
Sbjct: 698 SVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAM---TDAM 754
Query: 229 LAFSVLGELHSKLKSFGQMLLKYILRPLASCPSLHA---VIESQPNIVIIRFESIMTNLE 285
+ S +L S L+S +L + + +H+ I S+ + V E+I T L+
Sbjct: 755 VPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQTLLK 814
Query: 286 YPSP--SEVFTKIRLVLEVLQKQLLDLPLDTDLENEKTSTVPLAEMLGDMIWEDLSECLI 343
+E+ K + E L + + LE +K + + E L+
Sbjct: 815 SKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSL-- 872
Query: 344 KNCLVYSIPTNSSKLQQYEEIIQSTEEFENALKEMR 379
+ L YS ++ + QQ E + Q ++ +N L E +
Sbjct: 873 -SQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECK 907
>gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 41.6 bits (96), Expect = 0.003
Identities = 84/396 (21%), Positives = 156/396 (39%), Gaps = 48/396 (12%)
Query: 14 RLEKEDLGTRISRLTRRVEEIKGEVCNMISKKYSEFLPSMQSAQGLITQVDKLSEDIDLL 73
+L + + GT I EE+K C++I E L + + E+I L
Sbjct: 559 KLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKE-------KAFLFEKYQEAQEEIMKL 611
Query: 74 KSRIESEVRRDLHVSTGEFTDLKQQLERDSVVLSLLKQLQEFSTAIEEYNCALTE----- 128
K ++S++ ++ ++ E D+K+ + R ++ L KQ+ E S +E L +
Sbjct: 612 KDTLKSQMTQE---ASDEAEDMKEAMNR--MIDELNKQVSELSQLYKEAQAELEDYRKRK 666
Query: 129 ------KKYVTGAQRLE----------EAQKCLKLLKSRKCFDLKILKSLSMELTIQKQN 172
+Y+ A+ + +A+ L +KS+ L L L + QK+N
Sbjct: 667 SLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKEN 726
Query: 173 ---ILYHLGEEWQKLIVWKFPPSKDTSSLESYLQTELHL-YTEQSHKEEKTPMPPISSVL 228
I HL K K ++ E E+ + E+ EEK M + +
Sbjct: 727 SVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAM---TDAM 783
Query: 229 LAFSVLGELHSKLKSFGQMLLKYILRPLASCPSLHA---VIESQPNIVIIRFESIMTNLE 285
+ S +L S L+S +L + + +H+ I S+ + V E+I T L+
Sbjct: 784 VPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQTLLK 843
Query: 286 YPSP--SEVFTKIRLVLEVLQKQLLDLPLDTDLENEKTSTVPLAEMLGDMIWEDLSECLI 343
+E+ K + E L + + LE +K + + E L+
Sbjct: 844 SKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSL-- 901
Query: 344 KNCLVYSIPTNSSKLQQYEEIIQSTEEFENALKEMR 379
+ L YS ++ + QQ E + Q ++ +N L E +
Sbjct: 902 -SQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECK 936
>gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 41.6 bits (96), Expect = 0.003
Identities = 84/396 (21%), Positives = 156/396 (39%), Gaps = 48/396 (12%)
Query: 14 RLEKEDLGTRISRLTRRVEEIKGEVCNMISKKYSEFLPSMQSAQGLITQVDKLSEDIDLL 73
+L + + GT I EE+K C++I E L + + E+I L
Sbjct: 559 KLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKE-------KAFLFEKYQEAQEEIMKL 611
Query: 74 KSRIESEVRRDLHVSTGEFTDLKQQLERDSVVLSLLKQLQEFSTAIEEYNCALTE----- 128
K ++S++ ++ ++ E D+K+ + R ++ L KQ+ E S +E L +
Sbjct: 612 KDTLKSQMTQE---ASDEAEDMKEAMNR--MIDELNKQVSELSQLYKEAQAELEDYRKRK 666
Query: 129 ------KKYVTGAQRLE----------EAQKCLKLLKSRKCFDLKILKSLSMELTIQKQN 172
+Y+ A+ + +A+ L +KS+ L L L + QK+N
Sbjct: 667 SLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKEN 726
Query: 173 ---ILYHLGEEWQKLIVWKFPPSKDTSSLESYLQTELHL-YTEQSHKEEKTPMPPISSVL 228
I HL K K ++ E E+ + E+ EEK M + +
Sbjct: 727 SVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAM---TDAM 783
Query: 229 LAFSVLGELHSKLKSFGQMLLKYILRPLASCPSLHA---VIESQPNIVIIRFESIMTNLE 285
+ S +L S L+S +L + + +H+ I S+ + V E+I T L+
Sbjct: 784 VPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQTLLK 843
Query: 286 YPSP--SEVFTKIRLVLEVLQKQLLDLPLDTDLENEKTSTVPLAEMLGDMIWEDLSECLI 343
+E+ K + E L + + LE +K + + E L+
Sbjct: 844 SKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSL-- 901
Query: 344 KNCLVYSIPTNSSKLQQYEEIIQSTEEFENALKEMR 379
+ L YS ++ + QQ E + Q ++ +N L E +
Sbjct: 902 -SQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECK 936
>gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 41.6 bits (96), Expect = 0.003
Identities = 84/396 (21%), Positives = 156/396 (39%), Gaps = 48/396 (12%)
Query: 14 RLEKEDLGTRISRLTRRVEEIKGEVCNMISKKYSEFLPSMQSAQGLITQVDKLSEDIDLL 73
+L + + GT I EE+K C++I E L + + E+I L
Sbjct: 559 KLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKE-------KAFLFEKYQEAQEEIMKL 611
Query: 74 KSRIESEVRRDLHVSTGEFTDLKQQLERDSVVLSLLKQLQEFSTAIEEYNCALTE----- 128
K ++S++ ++ ++ E D+K+ + R ++ L KQ+ E S +E L +
Sbjct: 612 KDTLKSQMTQE---ASDEAEDMKEAMNR--MIDELNKQVSELSQLYKEAQAELEDYRKRK 666
Query: 129 ------KKYVTGAQRLE----------EAQKCLKLLKSRKCFDLKILKSLSMELTIQKQN 172
+Y+ A+ + +A+ L +KS+ L L L + QK+N
Sbjct: 667 SLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKEN 726
Query: 173 ---ILYHLGEEWQKLIVWKFPPSKDTSSLESYLQTELHL-YTEQSHKEEKTPMPPISSVL 228
I HL K K ++ E E+ + E+ EEK M + +
Sbjct: 727 SVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAM---TDAM 783
Query: 229 LAFSVLGELHSKLKSFGQMLLKYILRPLASCPSLHA---VIESQPNIVIIRFESIMTNLE 285
+ S +L S L+S +L + + +H+ I S+ + V E+I T L+
Sbjct: 784 VPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQTLLK 843
Query: 286 YPSP--SEVFTKIRLVLEVLQKQLLDLPLDTDLENEKTSTVPLAEMLGDMIWEDLSECLI 343
+E+ K + E L + + LE +K + + E L+
Sbjct: 844 SKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSL-- 901
Query: 344 KNCLVYSIPTNSSKLQQYEEIIQSTEEFENALKEMR 379
+ L YS ++ + QQ E + Q ++ +N L E +
Sbjct: 902 -SQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECK 936
>gi|56550047 uveal autoantigen with coiled-coil domains and ankyrin
repeats isoform 2 [Homo sapiens]
Length = 1403
Score = 41.2 bits (95), Expect = 0.004
Identities = 76/417 (18%), Positives = 180/417 (43%), Gaps = 40/417 (9%)
Query: 32 EEIKGEVCNMISKKYSEFLPSMQSAQGLITQVDKLSEDIDLLKSRIESEVRRDLHVSTGE 91
EE+K + + ++K E L + + + + K+ + ++LK +E+ + E
Sbjct: 853 EEVKMTLNDTLAKTNRELLDVKKKFEDINQEFVKIKDKNEILKRNLENTQNQ----IKAE 908
Query: 92 FTDLKQQLERDSVVLSLLKQLQEFSTAIEEYNCALTEKKYVTGAQRLEEAQKCLKLLKSR 151
+ L + + S + ++++Q+ + I N +++ VT ++ +K L ++
Sbjct: 909 YISLAEHEAKMSSLSQSMRKVQDSNAEILA-NYRKGQEEIVTLHAEIKAQKKELDTIQ-- 965
Query: 152 KCFDLKILKSLSMELTIQK-----QNILYHLGEEWQKLIVWKFPPSKDTSSLESY----- 201
+C +K +S E +K + + L E+ QK V + K+ +
Sbjct: 966 ECIKVKYAPIVSFEECERKFKATEKELKDQLSEQTQKYSVSEEEVKKNKQENDKLKKEIF 1025
Query: 202 -LQTELHLYT---EQSHKEEKTPMPPISSVLLAFSVLGELHSKLKSFGQMLLKYILRPLA 257
LQ +L T E+SH+ E+ + L + ++++K+ + L++ + +
Sbjct: 1026 TLQKDLRDKTVLIEKSHEMERALSRKTDELNKQLKDLSQKYTEVKNVKEKLVEENAKQTS 1085
Query: 258 SCPSLHAVIESQPNIVIIRFESIMTNLE--YPSPSEVFTKIRLVLEVLQKQLLDLPLDTD 315
++ +++ Q ++ + + E++ +L + E ++ E Q+ + L
Sbjct: 1086 EILAVQNLLQKQ-HVPLEQVEALKKSLNGTIENLKEELKSMQRCYEKEQQTVTKL--HQL 1142
Query: 316 LENEKTSTVPLAEMLGDMIWEDLSECLIKNCLVYSIPTNSSKLQQYEEIIQSTEEFENAL 375
LEN+K S+VPLAE L + +IK L + +K+++ ++ + + AL
Sbjct: 1143 LENQKNSSVPLAEHLQIKEAFEKEVGIIKASLREKEEESQNKMEEVSKLQSEVQNTKQAL 1202
Query: 376 KEMRF--------LKGDTTDLLKYARNINSHFAN------KKCQDVIVAARNLMTSE 418
K++ K +DL ++N AN + C++V+ A + ++++
Sbjct: 1203 KKLETREVVDLSKYKATKSDLETQISSLNEKLANLNRKYEEVCEEVLHAKKKEISAK 1259
Score = 30.0 bits (66), Expect = 8.6
Identities = 31/151 (20%), Positives = 62/151 (41%), Gaps = 20/151 (13%)
Query: 16 EKEDLGTRISRLTRRVEEIKGEVCNMISKKYSEFLPSMQSAQGLITQVDKLSEDIDLLKS 75
E ++ +S+L V+ K + + +++ + + L TQ+ L+E + L
Sbjct: 1180 ESQNKMEEVSKLQSEVQNTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLANLNR 1239
Query: 76 RIESEVRRDLHVSTGEFT--------------DLKQQLERD----SVVLSLLKQLQEFST 117
+ E LH E + ++K Q ER + + L +++QE +
Sbjct: 1240 KYEEVCEEVLHAKKKEISAKDEKELLHFSIEQEIKDQKERCDKSLTTITELQRRIQESAK 1299
Query: 118 AIEEYNCALTEKKYVTGAQRLEEAQKCLKLL 148
IE + +TE + +RL++A L L
Sbjct: 1300 QIEAKDNKITE--LLNDVERLKQALNGLSQL 1328
>gi|59850762 uveal autoantigen with coiled-coil domains and ankyrin
repeats isoform 1 [Homo sapiens]
Length = 1416
Score = 41.2 bits (95), Expect = 0.004
Identities = 76/417 (18%), Positives = 180/417 (43%), Gaps = 40/417 (9%)
Query: 32 EEIKGEVCNMISKKYSEFLPSMQSAQGLITQVDKLSEDIDLLKSRIESEVRRDLHVSTGE 91
EE+K + + ++K E L + + + + K+ + ++LK +E+ + E
Sbjct: 866 EEVKMTLNDTLAKTNRELLDVKKKFEDINQEFVKIKDKNEILKRNLENTQNQ----IKAE 921
Query: 92 FTDLKQQLERDSVVLSLLKQLQEFSTAIEEYNCALTEKKYVTGAQRLEEAQKCLKLLKSR 151
+ L + + S + ++++Q+ + I N +++ VT ++ +K L ++
Sbjct: 922 YISLAEHEAKMSSLSQSMRKVQDSNAEILA-NYRKGQEEIVTLHAEIKAQKKELDTIQ-- 978
Query: 152 KCFDLKILKSLSMELTIQK-----QNILYHLGEEWQKLIVWKFPPSKDTSSLESY----- 201
+C +K +S E +K + + L E+ QK V + K+ +
Sbjct: 979 ECIKVKYAPIVSFEECERKFKATEKELKDQLSEQTQKYSVSEEEVKKNKQENDKLKKEIF 1038
Query: 202 -LQTELHLYT---EQSHKEEKTPMPPISSVLLAFSVLGELHSKLKSFGQMLLKYILRPLA 257
LQ +L T E+SH+ E+ + L + ++++K+ + L++ + +
Sbjct: 1039 TLQKDLRDKTVLIEKSHEMERALSRKTDELNKQLKDLSQKYTEVKNVKEKLVEENAKQTS 1098
Query: 258 SCPSLHAVIESQPNIVIIRFESIMTNLE--YPSPSEVFTKIRLVLEVLQKQLLDLPLDTD 315
++ +++ Q ++ + + E++ +L + E ++ E Q+ + L
Sbjct: 1099 EILAVQNLLQKQ-HVPLEQVEALKKSLNGTIENLKEELKSMQRCYEKEQQTVTKL--HQL 1155
Query: 316 LENEKTSTVPLAEMLGDMIWEDLSECLIKNCLVYSIPTNSSKLQQYEEIIQSTEEFENAL 375
LEN+K S+VPLAE L + +IK L + +K+++ ++ + + AL
Sbjct: 1156 LENQKNSSVPLAEHLQIKEAFEKEVGIIKASLREKEEESQNKMEEVSKLQSEVQNTKQAL 1215
Query: 376 KEMRF--------LKGDTTDLLKYARNINSHFAN------KKCQDVIVAARNLMTSE 418
K++ K +DL ++N AN + C++V+ A + ++++
Sbjct: 1216 KKLETREVVDLSKYKATKSDLETQISSLNEKLANLNRKYEEVCEEVLHAKKKEISAK 1272
Score = 30.0 bits (66), Expect = 8.6
Identities = 31/151 (20%), Positives = 62/151 (41%), Gaps = 20/151 (13%)
Query: 16 EKEDLGTRISRLTRRVEEIKGEVCNMISKKYSEFLPSMQSAQGLITQVDKLSEDIDLLKS 75
E ++ +S+L V+ K + + +++ + + L TQ+ L+E + L
Sbjct: 1193 ESQNKMEEVSKLQSEVQNTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLANLNR 1252
Query: 76 RIESEVRRDLHVSTGEFT--------------DLKQQLERD----SVVLSLLKQLQEFST 117
+ E LH E + ++K Q ER + + L +++QE +
Sbjct: 1253 KYEEVCEEVLHAKKKEISAKDEKELLHFSIEQEIKDQKERCDKSLTTITELQRRIQESAK 1312
Query: 118 AIEEYNCALTEKKYVTGAQRLEEAQKCLKLL 148
IE + +TE + +RL++A L L
Sbjct: 1313 QIEAKDNKITE--LLNDVERLKQALNGLSQL 1341
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 38.9 bits (89), Expect = 0.018
Identities = 35/136 (25%), Positives = 63/136 (46%), Gaps = 24/136 (17%)
Query: 25 SRLTRRVEEIKGEVCNMISKKYSEFLPSMQSAQGLITQVDKLSEDIDLLKSRIESEVRRD 84
+RLT + +E++ E+C+ + + E + Q L + K+ ++I L+ ++E E
Sbjct: 904 ARLTAKKQELE-EICHDLEARVEE---EEERCQHLQAEKKKMQQNIQELEEQLEEE---- 955
Query: 85 LHVSTGEFTDLKQQLERDSVVLSLLKQLQEFSTAIEEYNCALTEKK---------YVTGA 135
E K QLE+ + L K+L+E +E+ NC L ++K + T
Sbjct: 956 ------ESARQKLQLEKVTTEAKL-KKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNL 1008
Query: 136 QRLEEAQKCLKLLKSR 151
EE K L LK++
Sbjct: 1009 TEEEEKSKSLAKLKNK 1024
>gi|215982791 myosin VA isoform 1 [Homo sapiens]
Length = 1855
Score = 38.5 bits (88), Expect = 0.024
Identities = 42/173 (24%), Positives = 79/173 (45%), Gaps = 26/173 (15%)
Query: 5 VTEVLAHSGRLEKEDLGTRISRLTRRVEEIKGEVCNMISKKYSEFLPSMQSAQGLITQVD 64
V E L + RL + L ++ E ++GE+ ++ + + Q L+ Q
Sbjct: 1338 VYEGLKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQ--------QQLLAQNL 1389
Query: 65 KLSEDIDLLKSRIESEVRRDLHVSTGEFTDLKQQLER-DSVVLSLLKQLQEFSTAIEEYN 123
+L + +RIE+ ++ ++ T E DL +QLE+ D V L KQL+ F+ I E
Sbjct: 1390 QLPPE-----ARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELE 1444
Query: 124 CALTEKKYVTGAQRLEEAQKCLKLLKSRKCF----------DLKILKSLSMEL 166
E ++ Q ++E + + + + K F + K++K+L +EL
Sbjct: 1445 VGQMEN--ISPGQIIDEPIRPVNIPRKEKDFQGMLEYKKEDEQKLVKNLILEL 1495
>gi|4502443 dystonin isoform 1e precursor [Homo sapiens]
Length = 2649
Score = 38.5 bits (88), Expect = 0.024
Identities = 44/178 (24%), Positives = 81/178 (45%), Gaps = 26/178 (14%)
Query: 15 LEKEDLGTRISRLTRRVEEIKGEVCNMISKKYSEFLPSM-QSAQGLITQVDKLSEDIDLL 73
LE L +IS L R V E+K + + E LP + ++A+ + + + EDI L
Sbjct: 1131 LENSKLTGKISELERMVAELKKQ-----KSRVEEELPKVREAAENELRKQQRNVEDISLQ 1185
Query: 74 KSRIESEV---RRDLHVSTGEFTDLKQQLER--------DSVVLSLLKQLQEFSTAIEEY 122
K R ESE RR+L E +++LER ++ ++ + L F +EE
Sbjct: 1186 KIRAESEAKQYRRELETIVREKEAAERELERVRQLTIEAEAKRAAVEENLLNFRNQLEEN 1245
Query: 123 NCAL------TEKKYVTGAQRLEEAQKCLKLLKSRKCFD---LKILKSLSMELTIQKQ 171
++K ++ ++ K ++ L+ ++ + LK++K + +L QKQ
Sbjct: 1246 TFTRRTLEDHLKRKDLSLNDLEQQKNKLMEELRRKRDNEEELLKLIKQMEKDLAFQKQ 1303
Score = 32.7 bits (73), Expect = 1.3
Identities = 37/153 (24%), Positives = 66/153 (43%), Gaps = 22/153 (14%)
Query: 351 IPTNSSKLQQYEEIIQSTEEFENALKEMRFLKGDTTDLLKYARNINSHFANKKCQDVIVA 410
+P+ S L+ ++ + ++ EEFE++LKE + + T LK H + ++
Sbjct: 305 LPSVESHLENHKNVHRAIEEFESSLKEAKISEIQMTAPLKLTYAEKLHRLESQYAKLLNT 364
Query: 411 ARN--LMTSEIHNTVKIIPDSKINVPELPTPDEDNKLEV-----QKVSNTQYHEVMNLEP 463
+RN +HN V + EL +E + EV ++ +N + + E
Sbjct: 365 SRNQERHLDTLHNFVSRATN------ELIWLNEKEEEEVAYDWSERNTNIARKKDYHAEL 418
Query: 464 ENTLDQHSFSLPTCRISESVKKLMELAYQTLLE 496
LDQ E++K + E+A Q LLE
Sbjct: 419 MRELDQK---------EENIKSVQEIAEQLLLE 442
>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
Length = 1417
Score = 38.5 bits (88), Expect = 0.024
Identities = 51/220 (23%), Positives = 92/220 (41%), Gaps = 34/220 (15%)
Query: 7 EVLAHSGRLEKEDLGTRISRLTRRVEEIKGEVCNM---ISKKYSEFLPSMQSAQGLITQV 63
E AH L+++ ++ LT ++K E+ +SK E + + + +
Sbjct: 965 ESAAHEADLKRQ----KVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHL 1020
Query: 64 DKLSEDIDLLKSRIES------EVRRDLHVSTGEFTDLKQQLERDSVVL--------SLL 109
+L +D K+ +E E+ + H + E T+ Q+ E L S L
Sbjct: 1021 SQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTL 1080
Query: 110 KQLQEFSTAIEEYNCALTEKKYVTGAQRLEEAQKCLKLLKSRKCFDLKI----------L 159
+QLQE +++ +L E+KY T E ++C ++ +K L++ L
Sbjct: 1081 RQLQELRDVLQKAQLSL-EEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWEL 1139
Query: 160 KSLSMELTIQKQNILYHLGEEWQKLIVWKFPPSKDTSSLE 199
K + ++T I H GE QK+I K + + S LE
Sbjct: 1140 KQRAAQVTHLDMTIREHRGEMEQKII--KLEGTLEKSELE 1177
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 38.1 bits (87), Expect = 0.032
Identities = 34/140 (24%), Positives = 71/140 (50%), Gaps = 20/140 (14%)
Query: 14 RLEKEDLGTRISRLTRRVEEIKGEVCNMISKKYSEFLPSMQSAQGLITQVDKLSEDIDLL 73
+LE +DL TR+ ++TR + ++C + ++ E A + +V +L+ D+
Sbjct: 1237 QLEVDDLLTRVEQMTRAKANAE-KLCTLYEERLHE-------ATAKLDKVTQLANDLAAQ 1288
Query: 74 KSRIESEVRRDLHVSTGEFTDLKQQLERDSVVLSLLKQLQEFSTAIEEYNCALTE--KKY 131
K+++ SE +GEF L++ E+++++ L ++ F+ IE+ L + K
Sbjct: 1289 KTKLWSE--------SGEF--LRRLEEKEALINQLSREKSNFTRQIEDLRGQLEKETKSQ 1338
Query: 132 VTGAQRLEEAQKCLKLLKSR 151
A L++AQ+ LL+ +
Sbjct: 1339 SALAHALQKAQRDCDLLREQ 1358
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 38.1 bits (87), Expect = 0.032
Identities = 34/134 (25%), Positives = 66/134 (49%), Gaps = 11/134 (8%)
Query: 26 RLTRRVEEIKGEVCNM------ISKKYSEFLPSMQSAQGLITQVDKLSEDIDLLKSRIES 79
+L + E+K E+ ++ +SK + F ++ + ++++ E+ L + + +
Sbjct: 1220 KLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSA 1279
Query: 80 EVRRDLHVSTGEFTDLKQQLERDSVVLSLLKQLQEFSTAIEEYNCALTE--KKYVTGAQR 137
+ R LH +GEF+ +Q E+D++V L + Q F+ IEE L E K T A
Sbjct: 1280 QKAR-LHTESGEFS--RQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHA 1336
Query: 138 LEEAQKCLKLLKSR 151
L+ A+ LL+ +
Sbjct: 1337 LQSARHDCDLLREQ 1350
>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
Length = 3907
Score = 37.7 bits (86), Expect = 0.041
Identities = 120/600 (20%), Positives = 236/600 (39%), Gaps = 92/600 (15%)
Query: 11 HSGRLEKEDLGTRI---SRLTRRVEEIKGEV--CNMISK--------KYSEF-LPSMQSA 56
HSG + + G + S ++ ++ EV C+ + + + EF + S
Sbjct: 88 HSGEITSHEQGFSVELESEISTTADDCSSEVNGCSFVMRTGKPTNLLREEEFGVDDSYSE 147
Query: 57 QGLITQVDKLSEDIDLLKSRIESEVRRDLHVSTGEFTDLKQQLERDSVVLSL--LKQLQE 114
QG ++D +ESE+ H E +L ++LE V L+QLQE
Sbjct: 148 QG--------AQDSPTHLEMMESELAGKQH----EIEELNRELEEMRVTYGTEGLQQLQE 195
Query: 115 FSTAIEEYNCALTE----------KKYVTGAQRLEEAQKCLKL------LKSRKCFDLKI 158
F AI++ + +T+ +K T + LE ++ KL L++ +
Sbjct: 196 FEAAIKQRDGIITQLTANLQQARREKDETMREFLELTEQSQKLQIQFQQLQASETLRNST 255
Query: 159 LKSLSMELTIQKQNILYHLGE-EWQKLIVWKFPPSKDTSSLE-SYLQTELHLY-TEQSHK 215
S + +L KQ IL H + E Q ++ + K+ +++ S+LQ ++ +Y EQ K
Sbjct: 256 HSSTAADLLQAKQQILTHQQQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKK 315
Query: 216 EEKTPMPPISSVLLAFSVLGELHSKLKSFGQMLLKYILRPLASCPSL-----HAVIESQP 270
E + I +++ EL++K+ + L+ + L + L +++
Sbjct: 316 VENSNKEEIQE---KETIIEELNTKIIEEEKKTLE-LKDKLTTADKLLGELQEQIVQKNQ 371
Query: 271 NIVIIRFESIMTNLEYPSPSEVFTKIRLVLEVLQKQ-LLDLPLDTD----LENE-----K 320
I ++ E + + SE ++ +E LQK+ D +TD +E E +
Sbjct: 372 EIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLE 431
Query: 321 TSTVPLAEMLGDMIWEDLSECLIKNCLVYSIPTNSSK------LQQYEEIIQSTEEFE-- 372
L EM G I + E + ++ K L+ Y I + ++ +
Sbjct: 432 QLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENALRSYSNITVNEDQIKLM 491
Query: 373 -NALKEMRFLKGDTTDLLKYARNINSHFANKKCQ-----DVIVAARNLMTSEIHNTVKII 426
A+ E+ DT + + +KC + +V + +I + I
Sbjct: 492 NVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFSREQIQRARQTI 551
Query: 427 --PDSKIN-VPELPTPDEDNKLEVQKVSNTQYHEVMNLEPENTLDQHSFSLPTCRISESV 483
+SK+N + + ED K E+ VS ++ + + L+ E + + L E +
Sbjct: 552 AEQESKLNEAHKSLSTVEDLKAEI--VSASESRKELELKHEAEVTNYKIKL------EML 603
Query: 484 KKLMELAYQTLLEATTSS-DQCAVQLFYSVRNIFHLFHDVVPTYHKENLQKLPQLAAIHH 542
+K + E+ + ++ QL +S + + H+ N++KL IH+
Sbjct: 604 EKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDNLGIHY 663
Score = 32.7 bits (73), Expect = 1.3
Identities = 34/137 (24%), Positives = 60/137 (43%), Gaps = 20/137 (14%)
Query: 17 KEDLGTRISRLTRRVEEIKGEVCNMISKKYSEFLPSMQSAQGLITQVDKLSEDIDLLKSR 76
++DL ++ L VEE + +K +E + Q Q L Q++K+ + +D +
Sbjct: 2016 RDDLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLD--EQA 2073
Query: 77 IESEVRRDLHVSTGEFTDLKQQLERDSVVLSLLKQLQEFST-AIEEYNCALTEKKYVTGA 135
I+ E RD+ F Q+LE+ V+ + + E T +E+ L EK
Sbjct: 2074 IDREHERDV------FQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEK------ 2121
Query: 136 QRLEEAQKCLKLLKSRK 152
KC +LL S++
Sbjct: 2122 -----TDKCSELLLSKE 2133
Score = 31.2 bits (69), Expect = 3.9
Identities = 29/119 (24%), Positives = 60/119 (50%), Gaps = 19/119 (15%)
Query: 80 EVRRDLHVSTGEFTDLKQQLERDSVVLSL-----LKQLQEF-STAIEEYNCALTEKKYVT 133
+++++L+V E DL+ Q+E + LSL + Q++E+ ++ C+L E+
Sbjct: 1094 KLQKELNVLKSEQNDLRLQMEAQRICLSLVYSTHVDQVREYMENEKDKALCSLKEELIFA 1153
Query: 134 GAQRLEEAQKC----LKLLKSRKCFDL---------KILKSLSMELTIQKQNILYHLGE 179
++++E QK L+ +K+++ D K+ K++S E + Q + LGE
Sbjct: 1154 QEEKIKELQKIHQLELQTMKTQETGDEGKPLHLLIGKLQKAVSEECSYFLQTLCSVLGE 1212
>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
Length = 3899
Score = 37.7 bits (86), Expect = 0.041
Identities = 120/600 (20%), Positives = 236/600 (39%), Gaps = 92/600 (15%)
Query: 11 HSGRLEKEDLGTRI---SRLTRRVEEIKGEV--CNMISK--------KYSEF-LPSMQSA 56
HSG + + G + S ++ ++ EV C+ + + + EF + S
Sbjct: 88 HSGEITSHEQGFSVELESEISTTADDCSSEVNGCSFVMRTGKPTNLLREEEFGVDDSYSE 147
Query: 57 QGLITQVDKLSEDIDLLKSRIESEVRRDLHVSTGEFTDLKQQLERDSVVLSL--LKQLQE 114
QG ++D +ESE+ H E +L ++LE V L+QLQE
Sbjct: 148 QG--------AQDSPTHLEMMESELAGKQH----EIEELNRELEEMRVTYGTEGLQQLQE 195
Query: 115 FSTAIEEYNCALTE----------KKYVTGAQRLEEAQKCLKL------LKSRKCFDLKI 158
F AI++ + +T+ +K T + LE ++ KL L++ +
Sbjct: 196 FEAAIKQRDGIITQLTANLQQARREKDETMREFLELTEQSQKLQIQFQQLQASETLRNST 255
Query: 159 LKSLSMELTIQKQNILYHLGE-EWQKLIVWKFPPSKDTSSLE-SYLQTELHLY-TEQSHK 215
S + +L KQ IL H + E Q ++ + K+ +++ S+LQ ++ +Y EQ K
Sbjct: 256 HSSTAADLLQAKQQILTHQQQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKK 315
Query: 216 EEKTPMPPISSVLLAFSVLGELHSKLKSFGQMLLKYILRPLASCPSL-----HAVIESQP 270
E + I +++ EL++K+ + L+ + L + L +++
Sbjct: 316 VENSNKEEIQE---KETIIEELNTKIIEEEKKTLE-LKDKLTTADKLLGELQEQIVQKNQ 371
Query: 271 NIVIIRFESIMTNLEYPSPSEVFTKIRLVLEVLQKQ-LLDLPLDTD----LENE-----K 320
I ++ E + + SE ++ +E LQK+ D +TD +E E +
Sbjct: 372 EIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLE 431
Query: 321 TSTVPLAEMLGDMIWEDLSECLIKNCLVYSIPTNSSK------LQQYEEIIQSTEEFE-- 372
L EM G I + E + ++ K L+ Y I + ++ +
Sbjct: 432 QLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENALRSYSNITVNEDQIKLM 491
Query: 373 -NALKEMRFLKGDTTDLLKYARNINSHFANKKCQ-----DVIVAARNLMTSEIHNTVKII 426
A+ E+ DT + + +KC + +V + +I + I
Sbjct: 492 NVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFSREQIQRARQTI 551
Query: 427 --PDSKIN-VPELPTPDEDNKLEVQKVSNTQYHEVMNLEPENTLDQHSFSLPTCRISESV 483
+SK+N + + ED K E+ VS ++ + + L+ E + + L E +
Sbjct: 552 AEQESKLNEAHKSLSTVEDLKAEI--VSASESRKELELKHEAEVTNYKIKL------EML 603
Query: 484 KKLMELAYQTLLEATTSS-DQCAVQLFYSVRNIFHLFHDVVPTYHKENLQKLPQLAAIHH 542
+K + E+ + ++ QL +S + + H+ N++KL IH+
Sbjct: 604 EKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDNLGIHY 663
Score = 33.1 bits (74), Expect = 1.0
Identities = 47/195 (24%), Positives = 81/195 (41%), Gaps = 30/195 (15%)
Query: 17 KEDLGTRISRLTRRVEEIKGEVCNMISKKYSEFLPSMQSAQGLITQVDKLSEDIDLLKSR 76
++DL ++ L VEE + +K +E + Q Q L Q++K+ + +D +
Sbjct: 2016 RDDLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLD--EQA 2073
Query: 77 IESEVRRDLHVSTGEFTDLKQQLERDSVVLSLLKQLQEFST-AIEEYNCALTEKKYVTGA 135
I+ E RD+ F Q+LE+ V+ + + E T +E+ L EK
Sbjct: 2074 IDREHERDV------FQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEK------ 2121
Query: 136 QRLEEAQKCLKLLKSRKCFDLKILKSLSMELTIQKQNILYHLGEEWQKLIV-----WKFP 190
KC +LL S++ I E + + + + + E Q L+V +
Sbjct: 2122 -----TDKCSELLLSKEQLQRDI-----QERNEEIEKLEFRVRELEQALLVEDRKHFGAV 2171
Query: 191 PSKDTSSLESYLQTE 205
+K SLE LQ E
Sbjct: 2172 EAKPELSLEVQLQAE 2186
Score = 31.2 bits (69), Expect = 3.9
Identities = 29/119 (24%), Positives = 60/119 (50%), Gaps = 19/119 (15%)
Query: 80 EVRRDLHVSTGEFTDLKQQLERDSVVLSL-----LKQLQEF-STAIEEYNCALTEKKYVT 133
+++++L+V E DL+ Q+E + LSL + Q++E+ ++ C+L E+
Sbjct: 1094 KLQKELNVLKSEQNDLRLQMEAQRICLSLVYSTHVDQVREYMENEKDKALCSLKEELIFA 1153
Query: 134 GAQRLEEAQKC----LKLLKSRKCFDL---------KILKSLSMELTIQKQNILYHLGE 179
++++E QK L+ +K+++ D K+ K++S E + Q + LGE
Sbjct: 1154 QEEKIKELQKIHQLELQTMKTQETGDEGKPLHLLIGKLQKAVSEECSYFLQTLCSVLGE 1212
>gi|209969819 hypothetical protein LOC253143 [Homo sapiens]
Length = 2151
Score = 37.4 bits (85), Expect = 0.054
Identities = 31/125 (24%), Positives = 61/125 (48%), Gaps = 11/125 (8%)
Query: 349 YSIPTNSSKLQQYEEIIQSTEEFENALKEMRFLKGDTTDLLKYARNI--NSHFANKKCQD 406
+S ++ S L Q EE Q+T N L + + K D L+ RN+ N+ C D
Sbjct: 506 HSEESSFSSLMQIEEAGQTTPVEPNILSKSFYTK-DCNSLVSIQRNLEGNTQLNEASCND 564
Query: 407 VIVAARNLMTSEIHNTVKIIPDSKINVPE------LPTPDEDNKLEVQKVSNTQYHEVMN 460
+ +++++ + +I P S++ P+ LP+P+ D + E +KV T + ++
Sbjct: 565 FLFERKSIVSLMPED--QISPVSEVLKPKQGTALLLPSPEFDYRPESEKVIQTSHDDIPL 622
Query: 461 LEPEN 465
L+ ++
Sbjct: 623 LDEQS 627
>gi|62548856 BCL2-associated athanogene 5 isoform a [Homo sapiens]
Length = 488
Score = 37.4 bits (85), Expect = 0.054
Identities = 45/178 (25%), Positives = 79/178 (44%), Gaps = 27/178 (15%)
Query: 23 RISRLTRRVEEIKGEVCNMISKKYSE-FLPSMQSAQGLITQVDKLSEDIDLLKSRIESEV 81
+I ++ +R+ EIK E+ ++ SE +L S QGLI Q+D++S L K+ E
Sbjct: 319 KIEKVLKRMREIKNELLQ--AQNPSELYLSSKTELQGLIGQLDEVS----LEKNPCIREA 372
Query: 82 RRDLHVSTG---EFTDLKQQLER-----------DSVVLSLLKQLQEFSTAIEEYNCALT 127
RR + + DLK+ LE+ V ++L L E + ++ T
Sbjct: 373 RRRAVIEVQTLITYIDLKEALEKRKLFACEEHPSHKAVWNVLGNLSEIQGEVLSFDGNRT 432
Query: 128 EKKYVTGAQRLEEAQKCLKLLKSRKCFDLKILKSLSMELTIQKQNILYHL---GEEWQ 182
+K Y+ + L + L + + K + ++ L QNIL +L +EW+
Sbjct: 433 DKNYIRLEELLTKQLLALDAVDPQGEEKCKAARKQAVRLA---QNILSYLDLKSDEWE 487
>gi|6631077 BCL2-associated athanogene 5 isoform b [Homo sapiens]
Length = 447
Score = 37.4 bits (85), Expect = 0.054
Identities = 45/178 (25%), Positives = 79/178 (44%), Gaps = 27/178 (15%)
Query: 23 RISRLTRRVEEIKGEVCNMISKKYSE-FLPSMQSAQGLITQVDKLSEDIDLLKSRIESEV 81
+I ++ +R+ EIK E+ ++ SE +L S QGLI Q+D++S L K+ E
Sbjct: 278 KIEKVLKRMREIKNELLQ--AQNPSELYLSSKTELQGLIGQLDEVS----LEKNPCIREA 331
Query: 82 RRDLHVSTG---EFTDLKQQLER-----------DSVVLSLLKQLQEFSTAIEEYNCALT 127
RR + + DLK+ LE+ V ++L L E + ++ T
Sbjct: 332 RRRAVIEVQTLITYIDLKEALEKRKLFACEEHPSHKAVWNVLGNLSEIQGEVLSFDGNRT 391
Query: 128 EKKYVTGAQRLEEAQKCLKLLKSRKCFDLKILKSLSMELTIQKQNILYHL---GEEWQ 182
+K Y+ + L + L + + K + ++ L QNIL +L +EW+
Sbjct: 392 DKNYIRLEELLTKQLLALDAVDPQGEEKCKAARKQAVRLA---QNILSYLDLKSDEWE 446
>gi|62548854 BCL2-associated athanogene 5 isoform b [Homo sapiens]
Length = 447
Score = 37.4 bits (85), Expect = 0.054
Identities = 45/178 (25%), Positives = 79/178 (44%), Gaps = 27/178 (15%)
Query: 23 RISRLTRRVEEIKGEVCNMISKKYSE-FLPSMQSAQGLITQVDKLSEDIDLLKSRIESEV 81
+I ++ +R+ EIK E+ ++ SE +L S QGLI Q+D++S L K+ E
Sbjct: 278 KIEKVLKRMREIKNELLQ--AQNPSELYLSSKTELQGLIGQLDEVS----LEKNPCIREA 331
Query: 82 RRDLHVSTG---EFTDLKQQLER-----------DSVVLSLLKQLQEFSTAIEEYNCALT 127
RR + + DLK+ LE+ V ++L L E + ++ T
Sbjct: 332 RRRAVIEVQTLITYIDLKEALEKRKLFACEEHPSHKAVWNVLGNLSEIQGEVLSFDGNRT 391
Query: 128 EKKYVTGAQRLEEAQKCLKLLKSRKCFDLKILKSLSMELTIQKQNILYHL---GEEWQ 182
+K Y+ + L + L + + K + ++ L QNIL +L +EW+
Sbjct: 392 DKNYIRLEELLTKQLLALDAVDPQGEEKCKAARKQAVRLA---QNILSYLDLKSDEWE 446
>gi|215982794 myosin VA isoform 2 [Homo sapiens]
Length = 1828
Score = 37.0 bits (84), Expect = 0.070
Identities = 40/169 (23%), Positives = 77/169 (45%), Gaps = 26/169 (15%)
Query: 9 LAHSGRLEKEDLGTRISRLTRRVEEIKGEVCNMISKKYSEFLPSMQSAQGLITQVDKLSE 68
L + RL + L ++ E ++GE+ ++ + + Q L+ Q +L
Sbjct: 1315 LKETNRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQ--------QQLLAQNLQLPP 1366
Query: 69 DIDLLKSRIESEVRRDLHVSTGEFTDLKQQLER-DSVVLSLLKQLQEFSTAIEEYNCALT 127
+ +RIE+ ++ ++ T E DL +QLE+ D V L KQL+ F+ I E
Sbjct: 1367 E-----ARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQM 1421
Query: 128 EKKYVTGAQRLEEAQKCLKLLKSRKCF----------DLKILKSLSMEL 166
E ++ Q ++E + + + + K F + K++K+L +EL
Sbjct: 1422 EN--ISPGQIIDEPIRPVNIPRKEKDFQGMLEYKKEDEQKLVKNLILEL 1468
>gi|19923899 coiled-coil domain containing 45 [Homo sapiens]
Length = 821
Score = 36.6 bits (83), Expect = 0.092
Identities = 48/204 (23%), Positives = 84/204 (41%), Gaps = 26/204 (12%)
Query: 60 ITQVDKLSEDI---DLLKSRIESEVRRDLHVSTGEFTDLKQQLERDSVVLSLLKQLQEFS 116
I QV++L ++ + K +++ E+ L T +K++ E + K+LQ+F
Sbjct: 591 IAQVEQLKKEACRENRSKKKLQDEIEEALRRHDLLTTLVKKEYEHN-------KRLQDFK 643
Query: 117 TAIEEYNCALTEKKYVTGAQRLEEAQK---------CLKLLKSRKCFDLKILKSLSMELT 167
I LT+ K Q++ A+K C K+++ R ++ K L
Sbjct: 644 DCIRRQR--LTQSKIKENRQQIVRARKYYDDYRVQLCAKMMRMRTREEMIFKKLFEEGLN 701
Query: 168 IQKQNILYHLGEEWQKLIVWKFPPSKDTSSLESYLQTELHLYTE---QSHKEEKTPMPPI 224
IQKQ + +K + + S+E+Y + + L E Q H+E K
Sbjct: 702 IQKQRLRDLRNYAKEKRDEQRRRHQDELDSMENYYKDQFSLLAEAISQEHQELKAREKSQ 761
Query: 225 SSVLLAFSVLGELHSKLKSFGQML 248
+ L V EL SK++ Q L
Sbjct: 762 AQTL--HKVKRELRSKMEKEIQQL 783
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 36.2 bits (82), Expect = 0.12
Identities = 39/160 (24%), Positives = 75/160 (46%), Gaps = 30/160 (18%)
Query: 5 VTEVLAHSGRLEKEDLGTRISRLTRRVEEIKGEVCNMISKKYSEFLPSMQSAQGLI---- 60
V EV A + + EKE L RL+++ E + E + + L ++Q+ QG++
Sbjct: 776 VAEVRAENLKKEKEMLKLSEVRLSQQRESLLAE-----QRGQNLLLTNLQTIQGILERSE 830
Query: 61 --------TQVDKLSEDIDLLKSRIESEVR------RDLHVSTGEFTDLKQQLERDSVV- 105
+Q++KL +I LK ++E+EV R+L V + D K+QL+ ++ +
Sbjct: 831 TETKQRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDV---QLLDTKRQLDTETNLH 887
Query: 106 ---LSLLKQLQEFSTAIEEYNCALTEKKYVTGAQRLEEAQ 142
LLK Q+ ++++ + + +QR + Q
Sbjct: 888 LNTKELLKNAQKEIATLKQHLSNMEVQVASQSSQRTGKGQ 927
Score = 33.1 bits (74), Expect = 1.0
Identities = 34/135 (25%), Positives = 67/135 (49%), Gaps = 18/135 (13%)
Query: 17 KEDLGTRISRLTRRVEEIKGEVCNMISKKYSEFLPSMQSAQGLITQVDKLSEDIDLLKSR 76
KED+ +S+L + E++ N + ++ +++ Q ++T L E ++ K +
Sbjct: 931 KEDVDDLVSQLRQTEEQV-----NDLKERLKTSTSNVEQYQAMVTS---LEESLNKEK-Q 981
Query: 77 IESEVRRDLHVSTGEFTDLKQQLERDSVVLSLLKQLQEFS----TAIEEYNCALTE-KKY 131
+ EVR+++ V E + + QLE+ ++ + K+ QE AIE L+E KK
Sbjct: 982 VTEEVRKNIEVRLKESAEFQTQLEKK--LMEVEKEKQELQDDKRRAIESMEQQLSELKKT 1039
Query: 132 VTGAQRLEEAQKCLK 146
++ Q E Q+ L+
Sbjct: 1040 LSSVQ--NEVQEALQ 1052
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 35.8 bits (81), Expect = 0.16
Identities = 31/148 (20%), Positives = 63/148 (42%), Gaps = 17/148 (11%)
Query: 14 RLEKEDLGTRISRLTRRVEEIKGEVCNMISKKYSEFLPSMQSAQGLI-----------TQ 62
++E +DL + +++ ++ ++C + + SE + Q LI T+
Sbjct: 1228 KMETDDLSSNAEAISKAKGNLE-KMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTE 1286
Query: 63 VDKLSEDIDLLKSRIESEVRRDLHVSTGEFTDLKQQLERDSVVLSLLKQLQEFSTAIEEY 122
+ S +D K + S++ R ST + +LK QLE ++ + L + S +
Sbjct: 1287 AGEYSRQLDE-KDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSS----RH 1341
Query: 123 NCALTEKKYVTGAQRLEEAQKCLKLLKS 150
+C L ++Y + E Q+ L S
Sbjct: 1342 DCDLLREQYEEEQEGKAELQRALSKANS 1369
>gi|55749708 outer dense fiber of sperm tails 2-like isoform b [Homo
sapiens]
Length = 513
Score = 35.8 bits (81), Expect = 0.16
Identities = 37/149 (24%), Positives = 68/149 (45%), Gaps = 21/149 (14%)
Query: 11 HSGRLEKEDLGTRISRLTRRVEEIKGEVCNMISKKYSEFLPSMQSAQGLI----TQVDKL 66
HS E E L ++L + +K EV + + + SE + + LI TQV KL
Sbjct: 204 HSIEYENETLNLENTKLKTTLAALKDEVVS-VENELSELQEVEKKQKTLIEMYKTQVQKL 262
Query: 67 SEDIDLLKSRIESEVRRDLHVSTGEFTDLKQQLERDSVVLSLLKQLQEFSTAIEEYNCAL 126
E +++KSR E+ + ++ ++ + ++++ + L L+++ + TA E
Sbjct: 263 QEAAEIVKSRCENLLHKNNQITKTKNKNVEKMRGQMESHLKELERVCDSLTAAE------ 316
Query: 127 TEKKYVTGAQRLEEAQKCLKLLKSRKCFD 155
+RL E Q+ L+ K KC D
Sbjct: 317 ---------RRLHECQESLQCCKG-KCAD 335
>gi|55749696 outer dense fiber of sperm tails 2-like isoform a [Homo
sapiens]
Length = 644
Score = 35.8 bits (81), Expect = 0.16
Identities = 37/149 (24%), Positives = 68/149 (45%), Gaps = 21/149 (14%)
Query: 11 HSGRLEKEDLGTRISRLTRRVEEIKGEVCNMISKKYSEFLPSMQSAQGLI----TQVDKL 66
HS E E L ++L + +K EV + + + SE + + LI TQV KL
Sbjct: 335 HSIEYENETLNLENTKLKTTLAALKDEVVS-VENELSELQEVEKKQKTLIEMYKTQVQKL 393
Query: 67 SEDIDLLKSRIESEVRRDLHVSTGEFTDLKQQLERDSVVLSLLKQLQEFSTAIEEYNCAL 126
E +++KSR E+ + ++ ++ + ++++ + L L+++ + TA E
Sbjct: 394 QEAAEIVKSRCENLLHKNNQITKTKNKNVEKMRGQMESHLKELERVCDSLTAAE------ 447
Query: 127 TEKKYVTGAQRLEEAQKCLKLLKSRKCFD 155
+RL E Q+ L+ K KC D
Sbjct: 448 ---------RRLHECQESLQCCKG-KCAD 466
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.132 0.373
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,989,091
Number of Sequences: 37866
Number of extensions: 1159780
Number of successful extensions: 4177
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 122
Number of HSP's that attempted gapping in prelim test: 4046
Number of HSP's gapped (non-prelim): 236
length of query: 779
length of database: 18,247,518
effective HSP length: 110
effective length of query: 669
effective length of database: 14,082,258
effective search space: 9421030602
effective search space used: 9421030602
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.