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Search of human proteins with 4759328
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4759328 class I cytokine receptor [Homo sapiens]
(636 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4759328 class I cytokine receptor [Homo sapiens] 1352 0.0
gi|4504643 interleukin 12 receptor, beta 2 precursor [Homo sapiens] 125 2e-28
gi|27437045 colony stimulating factor 3 receptor isoform d precu... 91 2e-18
gi|4503081 colony stimulating factor 3 receptor isoform a precur... 91 2e-18
gi|24496783 colony stimulating factor 3 receptor isoform c precu... 89 1e-17
gi|28610147 interleukin 6 signal transducer isoform 1 precursor ... 87 6e-17
gi|27437042 colony stimulating factor 3 receptor isoform b precu... 79 2e-14
gi|81158224 neuronal cell adhesion molecule isoform B precursor ... 65 2e-10
gi|4557040 oncostatin M receptor [Homo sapiens] 65 2e-10
gi|115430248 gp130-like monocyte receptor [Homo sapiens] 64 6e-10
gi|81158226 neuronal cell adhesion molecule isoform A precursor ... 62 1e-09
gi|4504993 leukemia inhibitory factor receptor precursor [Homo s... 55 2e-07
gi|189083786 leukemia inhibitory factor receptor precursor [Homo... 55 2e-07
gi|222352127 sidekick 2 [Homo sapiens] 44 6e-04
gi|21536468 AXL receptor tyrosine kinase isoform 2 [Homo sapiens] 42 0.001
gi|21536466 AXL receptor tyrosine kinase isoform 1 [Homo sapiens] 42 0.002
gi|28610149 interleukin 6 signal transducer isoform 2 precursor ... 41 0.003
gi|119220552 sidekick 1 [Homo sapiens] 41 0.004
gi|221316760 L1 cell adhesion molecule isoform 3 precursor [Homo... 39 0.011
gi|13435353 L1 cell adhesion molecule isoform 2 precursor [Homo ... 39 0.011
gi|4557707 L1 cell adhesion molecule isoform 1 precursor [Homo s... 39 0.011
gi|112734845 collagen, type XX, alpha 1 [Homo sapiens] 39 0.011
gi|218505839 interleukin 11 receptor, alpha isoform 1 precursor ... 39 0.015
gi|22212922 interleukin 11 receptor, alpha isoform 2 precursor [... 39 0.015
gi|4758594 interleukin 11 receptor, alpha isoform 1 precursor [H... 39 0.015
gi|109633041 protein tyrosine phosphatase, receptor type, F isof... 38 0.033
gi|109633039 protein tyrosine phosphatase, receptor type, F isof... 38 0.033
gi|24430212 interleukin 23 receptor precursor [Homo sapiens] 36 0.095
gi|75709184 contactin 3 [Homo sapiens] 36 0.12
gi|18860892 protein tyrosine phosphatase, receptor type, D isofo... 36 0.12
>gi|4759328 class I cytokine receptor [Homo sapiens]
Length = 636
Score = 1352 bits (3498), Expect = 0.0
Identities = 636/636 (100%), Positives = 636/636 (100%)
Query: 1 MRGGRGAPFWLWPLPKLALLPLLWVLFQRTRPQGSAGPLQCYGVGPLGDLNCSWEPLGDL 60
MRGGRGAPFWLWPLPKLALLPLLWVLFQRTRPQGSAGPLQCYGVGPLGDLNCSWEPLGDL
Sbjct: 1 MRGGRGAPFWLWPLPKLALLPLLWVLFQRTRPQGSAGPLQCYGVGPLGDLNCSWEPLGDL 60
Query: 61 GAPSELHLQSQKYRSNKTQTVAVAAGRSWVAIPREQLTMSDKLLVWGTKAGQPLWPPVFV 120
GAPSELHLQSQKYRSNKTQTVAVAAGRSWVAIPREQLTMSDKLLVWGTKAGQPLWPPVFV
Sbjct: 61 GAPSELHLQSQKYRSNKTQTVAVAAGRSWVAIPREQLTMSDKLLVWGTKAGQPLWPPVFV 120
Query: 121 NLETQMKPNAPRLGPDVDFSEDDPLEATVHWAPPTWPSHKVLICQFHYRRCQEAAWTLLE 180
NLETQMKPNAPRLGPDVDFSEDDPLEATVHWAPPTWPSHKVLICQFHYRRCQEAAWTLLE
Sbjct: 121 NLETQMKPNAPRLGPDVDFSEDDPLEATVHWAPPTWPSHKVLICQFHYRRCQEAAWTLLE 180
Query: 181 PELKTIPLTPVEIQDLELATGYKVYGRCRMEKEEDLWGEWSPILSFQTPPSAPKDVWVSG 240
PELKTIPLTPVEIQDLELATGYKVYGRCRMEKEEDLWGEWSPILSFQTPPSAPKDVWVSG
Sbjct: 181 PELKTIPLTPVEIQDLELATGYKVYGRCRMEKEEDLWGEWSPILSFQTPPSAPKDVWVSG 240
Query: 241 NLCGTPGGEEPLLLWKAPGPCVQVSYKVWFWVGGRELSPEGITCCCSLIPSGAEWARVSA 300
NLCGTPGGEEPLLLWKAPGPCVQVSYKVWFWVGGRELSPEGITCCCSLIPSGAEWARVSA
Sbjct: 241 NLCGTPGGEEPLLLWKAPGPCVQVSYKVWFWVGGRELSPEGITCCCSLIPSGAEWARVSA 300
Query: 301 VNATSWEPLTNLSLVCLDSASAPRSVAVSSIAGSTELLVTWQPGPGEPLEHVVDWARDGD 360
VNATSWEPLTNLSLVCLDSASAPRSVAVSSIAGSTELLVTWQPGPGEPLEHVVDWARDGD
Sbjct: 301 VNATSWEPLTNLSLVCLDSASAPRSVAVSSIAGSTELLVTWQPGPGEPLEHVVDWARDGD 360
Query: 361 PLEKLNWVRLPPGNLSALLPGNFTVGVPYRITVTAVSASGLASASSVWGFREELAPLVGP 420
PLEKLNWVRLPPGNLSALLPGNFTVGVPYRITVTAVSASGLASASSVWGFREELAPLVGP
Sbjct: 361 PLEKLNWVRLPPGNLSALLPGNFTVGVPYRITVTAVSASGLASASSVWGFREELAPLVGP 420
Query: 421 TLWRLQDAPPGTPAIAWGEVPRHQLRGHLTHYTLCAQSGTSPSVCMNVSGNTQSVTLPDL 480
TLWRLQDAPPGTPAIAWGEVPRHQLRGHLTHYTLCAQSGTSPSVCMNVSGNTQSVTLPDL
Sbjct: 421 TLWRLQDAPPGTPAIAWGEVPRHQLRGHLTHYTLCAQSGTSPSVCMNVSGNTQSVTLPDL 480
Query: 481 PWGPCELWVTASTIAGQGPPGPILRLHLPDNTLRWKVLPGILFLWGLFLLGCGLSLATSG 540
PWGPCELWVTASTIAGQGPPGPILRLHLPDNTLRWKVLPGILFLWGLFLLGCGLSLATSG
Sbjct: 481 PWGPCELWVTASTIAGQGPPGPILRLHLPDNTLRWKVLPGILFLWGLFLLGCGLSLATSG 540
Query: 541 RCYHLRHKVLPRWVWEKVPDPANSSSGQPHMEQVPEAQPLGDLPILEVEEMEPPPVMESS 600
RCYHLRHKVLPRWVWEKVPDPANSSSGQPHMEQVPEAQPLGDLPILEVEEMEPPPVMESS
Sbjct: 541 RCYHLRHKVLPRWVWEKVPDPANSSSGQPHMEQVPEAQPLGDLPILEVEEMEPPPVMESS 600
Query: 601 QPAQATAPLDSGYEKHFLPTPEELGLLGPPRPQVLA 636
QPAQATAPLDSGYEKHFLPTPEELGLLGPPRPQVLA
Sbjct: 601 QPAQATAPLDSGYEKHFLPTPEELGLLGPPRPQVLA 636
>gi|4504643 interleukin 12 receptor, beta 2 precursor [Homo sapiens]
Length = 862
Score = 125 bits (313), Expect = 2e-28
Identities = 131/497 (26%), Positives = 204/497 (41%), Gaps = 40/497 (8%)
Query: 137 VDFSEDDPLEATVHWAPPTWPSHKVLICQFHYRRCQEAAWTLLEPELKTIPLTPVEIQDL 196
+ F + T++W VL+ + YR W ++ T ++ DL
Sbjct: 232 IKFQKASVSRCTLYWRD----EGLVLLNRLRYRPSNSRLWNMVNV---TKAKGRHDLLDL 284
Query: 197 ELATGYKVYGRCRMEKEEDLWGEWSPILSFQTPPSAPK---DVWVSGNLCGTPGGEEPLL 253
+ T Y+ ++ + W +WS L QTP P DVW ++ L
Sbjct: 285 KPFTEYEFQISSKLHLYKGSWSDWSESLRAQTPEEEPTGMLDVWYMKRHIDY-SRQQISL 343
Query: 254 LWK------APGPCVQVSYKVWFWVGGRELSPE--GITCCCSLIPSGAEWA-RVSAVNA- 303
WK A G + + GG+ ++ G T ++IP WA VSA N+
Sbjct: 344 FWKNLSVSEARGKILHYQVTLQELTGGKAMTQNITGHTSWTTVIPRTGNWAVAVSAANSK 403
Query: 304 -TSWEPLTNLSLVCLDSASAPRSVAVSSIAGSTELLVTWQPGPGEPL---EHVVDWAR-- 357
+S N+ +C APR V+ +S G +LVTWQP +P E+VV+W
Sbjct: 404 GSSLPTRINIMNLCEAGLLAPRQVSANS-EGMDNILVTWQPPRKDPSAVQEYVVEWRELH 462
Query: 358 -DGDPLEKLNWVRLPPGNLSALLPGNFTVGVPYRITVTAVSASGLASASSVWGFREELAP 416
GD LNW+R P N+SAL+ N + Y I V A+S SS+ G + AP
Sbjct: 463 PGGDTQVPLNWLRSRPYNVSALISENIKSYICYEIRVYALSGDQ-GGCSSILGNSKHKAP 521
Query: 417 LVGPTLWRLQDAPPGTPAIAWGEVPRHQLRGHLTHYTLC---AQSGTSPSVC---MNVSG 470
L GP + + + G+ I+W +P + G L HY + S + P +C VS
Sbjct: 522 LSGPHINAITEEK-GSILISWNSIPVQEQMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQ 580
Query: 471 NTQSVTLPDLPWGPCELWVTASTIAGQGPPGPILRLHLPDNTLRWKVLPGILFLWGLFLL 530
N+ + P LW+TA T AG+ G L W + ++
Sbjct: 581 NSHPINSLQ-PRVTYVLWMTALTAAGESSHGNEREFCLQGKA-NWMAFVAPSICIAIIMV 638
Query: 531 GCGLSLATSGRCYHLRHKVLPRWVWEKVPDPANSSSGQPHMEQVPEAQ-PLGDLPILEVE 589
G + + + L + P+W ++PDPANS+ + + + Q PL L I
Sbjct: 639 GIFSTHYFQQKVFVLLAALRPQWCSREIPDPANSTCAKKYPIAEEKTQLPLDRLLIDWPT 698
Query: 590 EMEPPPVMESSQPAQAT 606
+P P++ S Q T
Sbjct: 699 PEDPEPLVISEVLHQVT 715
>gi|27437045 colony stimulating factor 3 receptor isoform d
precursor [Homo sapiens]
Length = 783
Score = 91.3 bits (225), Expect = 2e-18
Identities = 151/597 (25%), Positives = 224/597 (37%), Gaps = 79/597 (13%)
Query: 50 LNCSWEPLGDLGAPSELHLQSQKYRSN-KTQTVAVAA-----GRSWVAIPREQLTMSDKL 103
L C WEP + P+ L+S K R N +TQ ++ G+S IPR+ L + +
Sbjct: 140 LICQWEPGPETHLPTSFTLKSFKSRGNCQTQGDSILDCVPKDGQSHCCIPRKHLLLYQNM 199
Query: 104 LVW---GTKAGQPLWPPVFVNLETQMKPNAPRLGPDVDFSEDDPLEA---TVHWAPPTWP 157
+W G + P + ++ +K P L E P +A + W P
Sbjct: 200 GIWVQAENALGTSMSPQLCLDPMDVVKLEPPMLRTMDPSPEAAPPQAGCLQLCWEPWQPG 259
Query: 158 SHKVLICQFHYRRCQ-EAAWTLLEPELKTIPLTPV--EIQDLELATGYKVYGRCRMEKEE 214
H C+ ++ + EA+W L+ P +PL + E+ L AT Y + RC
Sbjct: 260 LHINQKCELRHKPQRGEASWALVGP----LPLEALQYELCGLLPATAYTLQIRCIRWPLP 315
Query: 215 DLWGEWSPILSFQTPPSAPK---DVWVSGNLCGTPGGEEPLLLWKAPGPCVQVSYKVWFW 271
W +WSP L +T AP D W + L WK P P + S ++ +
Sbjct: 316 GHWSDWSPSLELRTTERAPTVRLDTWWRQRQLDPRTVQ---LFWK-PVPLEEDSGRIQGY 371
Query: 272 VGGRELSPEGITCCCSLIPSGAEWARVSAVNATSWEPLTNL-------SLVCLDSA--SA 322
V S PSG A + N T +L +LV +SA S
Sbjct: 372 V-------------VSWRPSGQAGAILPLCNTTELSCTFHLPSEAQEVALVAYNSAGTSR 418
Query: 323 PRSVAVSSIAGST------------ELLVTWQPGPGEPLEHVVDWARDGDPLEKLN--WV 368
P V S G L V W+P P +V++W N W
Sbjct: 419 PTPVVFSESRGPALTRLHAMARDPHSLWVGWEPPNPWPQGYVIEWGLGPPSASNSNKTWR 478
Query: 369 RLPPGNLSA-LLPGNFTVGVPYRITVTAVSASGLASASSVWGFREELAPLVGPTLWRLQD 427
G + LL N Y I VT + + + V+ + +E+AP P L L+
Sbjct: 479 MEQNGRATGFLLKENIRPFQLYEIIVTPLYQDTMGPSQHVYAYSQEMAPSHAPEL-HLKH 537
Query: 428 APPGTPAIAWGEVPRHQLRGHLTHYTLCAQSGTSPSVCMNVSGNTQSVTLPDLPWGPCEL 487
+ W P + LTHYT+ + + S ++ +++ L L P L
Sbjct: 538 IGKTWAQLEWVPEPPELGKSPLTHYTIFWTNAQNQSFSAILNASSRGFVLHGLE--PASL 595
Query: 488 WVTASTIAGQGPPGPILRLHLPDNTLRWKVLPGILFLWGLFLLGCGLSLATSGRCYHLRH 547
+ A Q L L T L IL L+GL LL L T+ C
Sbjct: 596 YHIHLMAASQAGATNSTVLTLMTLTPEGSELHIILGLFGLLLLLTCLC-GTAWLCCSPNR 654
Query: 548 KVLPRWVWEKVPDPANSSSG-------QPHMEQVP--EAQPLGDLPILEVEEMEPPP 595
K +W VPDPA+SS G + Q+P P+ L +LE +E +P P
Sbjct: 655 K---NPLWPSVPDPAHSSLGSWVPTIMEEDAFQLPGLGTPPITKLTVLEEDEKKPVP 708
>gi|4503081 colony stimulating factor 3 receptor isoform a precursor
[Homo sapiens]
Length = 836
Score = 91.3 bits (225), Expect = 2e-18
Identities = 151/597 (25%), Positives = 224/597 (37%), Gaps = 79/597 (13%)
Query: 50 LNCSWEPLGDLGAPSELHLQSQKYRSN-KTQTVAVAA-----GRSWVAIPREQLTMSDKL 103
L C WEP + P+ L+S K R N +TQ ++ G+S IPR+ L + +
Sbjct: 140 LICQWEPGPETHLPTSFTLKSFKSRGNCQTQGDSILDCVPKDGQSHCCIPRKHLLLYQNM 199
Query: 104 LVW---GTKAGQPLWPPVFVNLETQMKPNAPRLGPDVDFSEDDPLEA---TVHWAPPTWP 157
+W G + P + ++ +K P L E P +A + W P
Sbjct: 200 GIWVQAENALGTSMSPQLCLDPMDVVKLEPPMLRTMDPSPEAAPPQAGCLQLCWEPWQPG 259
Query: 158 SHKVLICQFHYRRCQ-EAAWTLLEPELKTIPLTPV--EIQDLELATGYKVYGRCRMEKEE 214
H C+ ++ + EA+W L+ P +PL + E+ L AT Y + RC
Sbjct: 260 LHINQKCELRHKPQRGEASWALVGP----LPLEALQYELCGLLPATAYTLQIRCIRWPLP 315
Query: 215 DLWGEWSPILSFQTPPSAPK---DVWVSGNLCGTPGGEEPLLLWKAPGPCVQVSYKVWFW 271
W +WSP L +T AP D W + L WK P P + S ++ +
Sbjct: 316 GHWSDWSPSLELRTTERAPTVRLDTWWRQRQLDPRTVQ---LFWK-PVPLEEDSGRIQGY 371
Query: 272 VGGRELSPEGITCCCSLIPSGAEWARVSAVNATSWEPLTNL-------SLVCLDSA--SA 322
V S PSG A + N T +L +LV +SA S
Sbjct: 372 V-------------VSWRPSGQAGAILPLCNTTELSCTFHLPSEAQEVALVAYNSAGTSR 418
Query: 323 PRSVAVSSIAGST------------ELLVTWQPGPGEPLEHVVDWARDGDPLEKLN--WV 368
P V S G L V W+P P +V++W N W
Sbjct: 419 PTPVVFSESRGPALTRLHAMARDPHSLWVGWEPPNPWPQGYVIEWGLGPPSASNSNKTWR 478
Query: 369 RLPPGNLSA-LLPGNFTVGVPYRITVTAVSASGLASASSVWGFREELAPLVGPTLWRLQD 427
G + LL N Y I VT + + + V+ + +E+AP P L L+
Sbjct: 479 MEQNGRATGFLLKENIRPFQLYEIIVTPLYQDTMGPSQHVYAYSQEMAPSHAPEL-HLKH 537
Query: 428 APPGTPAIAWGEVPRHQLRGHLTHYTLCAQSGTSPSVCMNVSGNTQSVTLPDLPWGPCEL 487
+ W P + LTHYT+ + + S ++ +++ L L P L
Sbjct: 538 IGKTWAQLEWVPEPPELGKSPLTHYTIFWTNAQNQSFSAILNASSRGFVLHGLE--PASL 595
Query: 488 WVTASTIAGQGPPGPILRLHLPDNTLRWKVLPGILFLWGLFLLGCGLSLATSGRCYHLRH 547
+ A Q L L T L IL L+GL LL L T+ C
Sbjct: 596 YHIHLMAASQAGATNSTVLTLMTLTPEGSELHIILGLFGLLLLLTCLC-GTAWLCCSPNR 654
Query: 548 KVLPRWVWEKVPDPANSSSG-------QPHMEQVP--EAQPLGDLPILEVEEMEPPP 595
K +W VPDPA+SS G + Q+P P+ L +LE +E +P P
Sbjct: 655 K---NPLWPSVPDPAHSSLGSWVPTIMEEDAFQLPGLGTPPITKLTVLEEDEKKPVP 708
>gi|24496783 colony stimulating factor 3 receptor isoform c
precursor [Homo sapiens]
Length = 863
Score = 89.0 bits (219), Expect = 1e-17
Identities = 154/609 (25%), Positives = 228/609 (37%), Gaps = 77/609 (12%)
Query: 50 LNCSWEPLGDLGAPSELHLQSQKYRSN-KTQTVAVAA-----GRSWVAIPREQLTMSDKL 103
L C WEP + P+ L+S K R N +TQ ++ G+S IPR+ L + +
Sbjct: 140 LICQWEPGPETHLPTSFTLKSFKSRGNCQTQGDSILDCVPKDGQSHCCIPRKHLLLYQNM 199
Query: 104 LVW---GTKAGQPLWPPVFVNLETQMKPNAPRLGPDVDFSEDDPLEA---TVHWAPPTWP 157
+W G + P + ++ +K P L E P +A + W P
Sbjct: 200 GIWVQAENALGTSMSPQLCLDPMDVVKLEPPMLRTMDPSPEAAPPQAGCLQLCWEPWQPG 259
Query: 158 SHKVLICQFHYRRCQ-EAAWTLLEPELKTIPLTPV--EIQDLELATGYKVYGRCRMEKEE 214
H C+ ++ + EA+W L+ P +PL + E+ L AT Y + RC
Sbjct: 260 LHINQKCELRHKPQRGEASWALVGP----LPLEALQYELCGLLPATAYTLQIRCIRWPLP 315
Query: 215 DLWGEWSPILSFQTPPSAPK---DVWVSGNLCGTPGGEEPLLLWKAPGPCVQVSYKVWFW 271
W +WSP L +T AP D W + L WK P P + S ++ +
Sbjct: 316 GHWSDWSPSLELRTTERAPTVRLDTWWRQRQLDPRTVQ---LFWK-PVPLEEDSGRIQGY 371
Query: 272 VGGRELSPEGITCCCSLIPSGAEWARVSAVNATSWEPLTNL-------SLVCLDSA--SA 322
V S PSG A + N T +L +LV +SA S
Sbjct: 372 V-------------VSWRPSGQAGAILPLCNTTELSCTFHLPSEAQEVALVAYNSAGTSR 418
Query: 323 PRSVAVSSIAGST------------ELLVTWQPGPGEPLEHVVDWARDGDPLEKLN--WV 368
P V S G L V W+P P +V++W N W
Sbjct: 419 PTPVVFSESRGPALTRLHAMARDPHSLWVGWEPPNPWPQGYVIEWGLGPPSASNSNKTWR 478
Query: 369 RLPPGNLSA-LLPGNFTVGVPYRITVTAVSASGLASASSVWGFREELAPLVGPTLWRLQD 427
G + LL N Y I VT + + + V+ + +E+AP P L L+
Sbjct: 479 MEQNGRATGFLLKENIRPFQLYEIIVTPLYQDTMGPSQHVYAYSQEMAPSHAPEL-HLKH 537
Query: 428 APPGTPAIAWGEVPRHQLRGHLTHYTLCAQSGTSPSVCMNVSGNTQSVTLPDLPWGPCEL 487
+ W P + LTHYT+ + + S ++ +++ L L P L
Sbjct: 538 IGKTWAQLEWVPEPPELGKSPLTHYTIFWTNAQNQSFSAILNASSRGFVLHGLE--PASL 595
Query: 488 WVTASTIAGQGPPGPILRLHLPDNTLRWKVLPGILFLWGLFLLGCGLSLATSGRCYHLRH 547
+ A Q L L T L IL L+GL LL L T+ C
Sbjct: 596 YHIHLMAASQAGATNSTVLTLMTLTPEGSELHIILGLFGLLLLLTCLC-GTAWLCCSPNR 654
Query: 548 KVLPRWVWEKVPDPANSSSGQ---PHMEQVP---EAQPLGDLPILEVEEMEPPPVMESSQ 601
K +W VPDPA+SS G ME++P + Q LG + P V ++ Q
Sbjct: 655 K---NPLWPSVPDPAHSSLGSWVPTIMEELPGPRQGQWLGQTSEMSRALTPHPCVQDAFQ 711
Query: 602 -PAQATAPL 609
P T P+
Sbjct: 712 LPGLGTPPI 720
>gi|28610147 interleukin 6 signal transducer isoform 1 precursor
[Homo sapiens]
Length = 918
Score = 86.7 bits (213), Expect = 6e-17
Identities = 105/498 (21%), Positives = 180/498 (36%), Gaps = 34/498 (6%)
Query: 125 QMKPNAPRLGPDVDFSEDDPLEATVHWAPPTWPSHKVLICQFHYRRCQEAAWTLLEPELK 184
++KPN P V SE+ + W P+ S +L YR + W+ + PE
Sbjct: 219 KVKPNPPH-NLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDT 277
Query: 185 TIPLTPVEIQDLELATGYKVYGRCRMEKEEDLWGEWSPI---LSFQTPPSAPKDVWVSGN 241
+ +QDL+ T Y RC E + W +WS ++++ PS W +
Sbjct: 278 ASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKID 337
Query: 242 LCGTPGGEEPLLLWK------APGPCVQVSYKVWFWVGGRELSPEGITCCCSLIPSGAEW 295
T G L+WK A G + + W + T + +
Sbjct: 338 PSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYL 397
Query: 296 ARVSAVNATSWEPLTNLSLVCLDSASAPRSVAVSSIAGSTELLVTWQPGPGEPLEHVVDW 355
A ++ N L++ D + + + + L V W +++++W
Sbjct: 398 ATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEW 457
Query: 356 ARDGDPLEKL-NWVRLPPGNLSALLPGNFTVGVPYRITVTAVSASGLASASSVWGFREEL 414
D + +W + L GN Y ITVT V A G S S+ + ++
Sbjct: 458 CVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQA 517
Query: 415 APLVGPTLWRLQDAPPGTPAIAWGEVPRHQLRGHLTHYTLCAQSGTSPSVCMNVSGNTQS 474
P GPT+ R + + W ++P G + +YT+ ++ +NV +
Sbjct: 518 PPSKGPTV-RTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTE 576
Query: 475 VTLPDLPWGPCELWVTASTIAGQGPPGPILRLHLP---DNTLRWKVLPGILFLWGLFLLG 531
TL L + A+ G GP P + V+P L LLG
Sbjct: 577 YTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLG 636
Query: 532 CGLSLATSGRCYHLRHKVLPRWVWEKVPDPANSSSGQ--PH---------MEQVPEAQPL 580
C++ R ++ + +W VPDP+ S Q PH +Q+
Sbjct: 637 VLF-------CFNKR-DLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNF 688
Query: 581 GDLPILEVEEMEPPPVME 598
D+ ++E+E + P E
Sbjct: 689 TDVSVVEIEANDKKPFPE 706
>gi|27437042 colony stimulating factor 3 receptor isoform b
precursor [Homo sapiens]
Length = 769
Score = 78.6 bits (192), Expect = 2e-14
Identities = 150/617 (24%), Positives = 220/617 (35%), Gaps = 103/617 (16%)
Query: 50 LNCSWEPLGDLGAPSELHLQSQKYRSN-KTQTVAV-----AAGRSWVAIPREQLTMSDKL 103
L C WEP + P+ L+S K R N +TQ ++ G+S IPR+ L + +
Sbjct: 140 LICQWEPGPETHLPTSFTLKSFKSRGNCQTQGDSILDCVPKDGQSHCCIPRKHLLLYQNM 199
Query: 104 LVW---GTKAGQPLWPPVFVNLETQMKPNAPRLGPDVDFSEDDPLEA---TVHWAPPTWP 157
+W G + P + ++ +K P L E P +A + W P
Sbjct: 200 GIWVQAENALGTSMSPQLCLDPMDVVKLEPPMLRTMDPSPEAAPPQAGCLQLCWEPWQPG 259
Query: 158 SHKVLICQF-HYRRCQEAAWTLLEPELKTIPLTPV--EIQDLELATGYKVYGRCRMEKEE 214
H C+ H + EA+W L+ P +PL + E+ L AT Y + RC
Sbjct: 260 LHINQKCELRHKPQRGEASWALVGP----LPLEALQYELCGLLPATAYTLQIRCIRWPLP 315
Query: 215 DLWGEWSPILSFQTPPSAPK---DVWVSGNLCGTPGGEEPLLLWKAPGPCVQVSYKVWFW 271
W +WSP L +T AP D W L WK P P + S ++ +
Sbjct: 316 GHWSDWSPSLELRTTERAPTVRLDTWWRQRQLDP---RTVQLFWK-PVPLEEDSGRIQGY 371
Query: 272 VGGRELSPEGITCCCSLIPSGAEWARVSAVNATSWEPLTNL-------SLVCLDSA--SA 322
V S PSG A + N T +L +LV +SA S
Sbjct: 372 V-------------VSWRPSGQAGAILPLCNTTELSCTFHLPSEAQEVALVAYNSAGTSR 418
Query: 323 PRSVAVSSIAGST------------ELLVTWQPGPGEPLEHVVDWARDGDPLEKLN--WV 368
P V S G L V W+P P +V++W N W
Sbjct: 419 PTPVVFSESRGPALTRLHAMARDPHSLWVGWEPPNPWPQGYVIEWGLGPPSASNSNKTWR 478
Query: 369 RLPPGNLSA-LLPGNFTVGVPYRITVTAVSASGLASASSVWGFREELAPLVGPTLWRLQD 427
G + LL N Y I VT + + + V+ + +E+AP P L L+
Sbjct: 479 MEQNGRATGFLLKENIRPFQLYEIIVTPLYQDTMGPSQHVYAYSQEMAPSHAPEL-HLKH 537
Query: 428 APPGTPAIAWGEVPRHQLRGHLTHYTLCAQSGTSPSVCMNVSGNTQSVTLPDLPWGPCEL 487
+ W P + LTHYT+ + + S ++ +++ L L P L
Sbjct: 538 IGKTWAQLEWVPEPPELGKSPLTHYTIFWTNAQNQSFSAILNASSRGFVLHGLE--PASL 595
Query: 488 W-----------VTASTI--------AGQGPPGPILRLHLPDNTLRWKVLPGILFLWGLF 528
+ T ST+ AG+ P G + + L T W PG W
Sbjct: 596 YHIHLMAASQAGATNSTVLTLMTLTPAGRIPSGQVSQTQL---TAAW--APGCPQSWRRM 650
Query: 529 LLGCGLSLATSGRCYHLRHKVLPRWVWEKVPDPANSSSGQPHMEQVPEAQPLGDLPILE- 587
C +LA RH W ++ + G P Q P A PL P+
Sbjct: 651 PSSCP-ALA--------RHPSPSSQCWRRM--KRSRCPGSPITAQRPVASPLWSRPMCSR 699
Query: 588 -VEEMEPPPVMESSQPA 603
+E PP S PA
Sbjct: 700 GTQEQFPPSPNPSLAPA 716
>gi|81158224 neuronal cell adhesion molecule isoform B precursor
[Homo sapiens]
Length = 1183
Score = 65.1 bits (157), Expect = 2e-10
Identities = 84/318 (26%), Positives = 119/318 (37%), Gaps = 34/318 (10%)
Query: 221 SPILSFQTPPSAPKDVWV------SGNLCGTPGGEEPLLLWKAPGPCVQVSYKVWFWVGG 274
S +LS P+ P D+ + S L TPG + + K +K W
Sbjct: 622 SAVLSVVDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQ 681
Query: 275 RELSPEGITCCCSLIPSGAEWARVSAVNATSWEPLTNLSLVCLDSASAP--RSVAVSSIA 332
E+S T L P RV AVN+ + S L AS P AV +
Sbjct: 682 TEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLG 741
Query: 333 GSTE-LLVTWQP-------GPGEPLEHVVDWA-RDGDPLEKLNWVRLPPGNLSALLPGNF 383
+ L++TW+P GPG L++ V W +DGD W + N+S +
Sbjct: 742 SEPDNLVITWKPLNGFESNGPG--LQYKVSWRQKDGDD----EWTSVVVANVSKYIVSGT 795
Query: 384 TVGVPYRITVTAVSASGLASASSV-WGFREELAPLVGPTLWRLQDAPPGTPAIAWGEVPR 442
VPY I V A++ G A +V G E P+V P R+ + W VP
Sbjct: 796 PTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPL 855
Query: 443 HQLRGHLTHYTLCAQSGTSPS---------VCMNVSGNTQSVTLPDL-PWGPCELWVTAS 492
+RGHL Y + S S + G+ LP L P+ L V
Sbjct: 856 KSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVV 915
Query: 493 TIAGQGPPGPILRLHLPD 510
G+GP P + P+
Sbjct: 916 NGKGEGPASPDRVFNTPE 933
>gi|4557040 oncostatin M receptor [Homo sapiens]
Length = 979
Score = 64.7 bits (156), Expect = 2e-10
Identities = 90/409 (22%), Positives = 157/409 (38%), Gaps = 54/409 (13%)
Query: 193 IQDLELATGYKVYGRCRMEKEEDLWGEWSP--ILSFQTPPSAPKDVWVSGNLCGTPGGEE 250
+ +LE AT Y RC W EWS + + PS DVW +L PG
Sbjct: 391 LSELEPATEYMARVRCADASHFWKWSEWSGQNFTTLEAAPSEAPDVWRIVSL--EPGNHT 448
Query: 251 PLLLWKAPGPCVQVSYKVWFWVGGRELSPEGITCCCSLIPSGAEWAR-----------VS 299
L WK P + + K+ F+ E + + IP+ A + V
Sbjct: 449 VTLFWK-PLSKLHANGKILFYNVVVENLDKPSSSELHSIPAPANSTKLILDRCSYQICVI 507
Query: 300 AVNATSWEPLTNLSLVCLDSASAPRSVAVSSIAGSTE-LLVTWQPGPGEPLEHVVDWA-R 357
A N+ P S++ + + + V IAG+ ++W+P PG+ + +VVDW
Sbjct: 508 ANNSVGASPA---SVIVISADPENKEVEEERIAGTEGGFSLSWKPQPGDVIGYVVDWCDH 564
Query: 358 DGDPLEKLNWVRLPPGNLSALLPGN-FTVGVPYRITVTAVSASGLAS-ASSVWGFREELA 415
D L W + P S ++ + F GV Y + +S +A G+ +ELA
Sbjct: 565 TQDVLGDFQWKNVGPNTTSTVISTDAFRPGVRYDFRIYGLSTKRIACLLEKKTGYSQELA 624
Query: 416 PLVGPTLWRLQDAPPGTPAIAWGEVPRHQLRGHLTHYTLCAQSG-------------TSP 462
P P + + + ++W + G + Y + +S +
Sbjct: 625 PSDNPHV-LVDTLTSHSFTLSWKDYSTESQPGFIQGYHVYLKSKARQCHPRFEKAVLSDG 683
Query: 463 SVC--MNVSGNTQSVTLPD--LPWGPCELWVTASTIAGQGPPGPILRLHLPD--NTLRWK 516
S C + + + D P E ++T T AG+GP ++ PD +++
Sbjct: 684 SECCKYKIDNPEEKALIVDNLKPESFYEFFITPFTSAGEGPSATFTKVTTPDEHSSMLIH 743
Query: 517 VLPGILFLWGLFLLGCGLSLATSGRCYHLRHKVLPRWVWEKVPDPANSS 565
+L ++F L ++ C +L+ + + + +PDP SS
Sbjct: 744 ILLPMVFCVLLIMVMC-----------YLKSQWIKETCYPDIPDPYKSS 781
>gi|115430248 gp130-like monocyte receptor [Homo sapiens]
Length = 764
Score = 63.5 bits (153), Expect = 6e-10
Identities = 89/389 (22%), Positives = 144/389 (37%), Gaps = 24/389 (6%)
Query: 196 LELATGYKVYGRCRMEKEEDLWGEWSPILSFQTPPSAP--KDVWVSGNLCGTPGGEEPLL 253
L+ T Y + RC + KE W +WS T AP ++W G L
Sbjct: 223 LQPFTEYVIALRCAV-KESKFWSDWSQEKMGMTEEEAPCGLELWRVLKPAEADGRRPVRL 281
Query: 254 LWK----APGPCVQVSYKVWFWVGGRELSPEGITCCCSLIPS--GAE--WARVSAVNATS 305
LWK AP + Y +W++ E + + G E W + + N+
Sbjct: 282 LWKKARGAPVLEKTLGYNIWYYPESNTNLTETMNTTNQQLELHLGGESFWVSMISYNSLG 341
Query: 306 WEPLTNLSLVCLDSASAPRSVAVSSIAGSTELLVTWQPGPGEPLEHVVDWARDGDPLEK- 364
P+ L + + S + + +L+V WQ + +++W D D
Sbjct: 342 KSPVATLRIPAIQEKSFQCIEVMQACVAEDQLVVKWQSSALDVNTWMIEWFPDVDSEPTT 401
Query: 365 LNWVRLPPGNLSALLPGNFTVGVPYRITVTAVSASGLASASSVWGFREELAPLVGPTLWR 424
L+W + + Y I+V + + S+ + +E P GP +
Sbjct: 402 LSWESVSQATNWTIQQDKLKPFWCYNISVYPMLHDKVGEPYSIQAYAKEGVPSEGPET-K 460
Query: 425 LQDAPPGTPAIAWGEVPRHQLRGHLTHYTLCAQSGTSPSVCMNVSGNTQSVTLPDLPWGP 484
+++ T I W E+P+ + +G + +YT+ Q+ V+ + L L
Sbjct: 461 VENIGVKTVTITWKEIPKSERKGIICNYTIFYQAEGGKGFSKTVNSSILQYGLESLKRKT 520
Query: 485 CEL-WVTASTIAGQGPPGPILRLHLPDNTLRWKVLPGILFLWGLFLLGCG-LSLATSGRC 542
+ V AST AG G G + TL + V IL L+G G L L
Sbjct: 521 SYIVQVMASTSAG-GTNGTSINF----KTLSFSVFEIILI---TSLIGGGLLILIILTVA 572
Query: 543 YHLRH-KVLPRWVWEKVPDPANSSSGQPH 570
Y L+ L W VP+PA SS H
Sbjct: 573 YGLKKPNKLTHLCWPTVPNPAESSIATWH 601
>gi|81158226 neuronal cell adhesion molecule isoform A precursor
[Homo sapiens]
Length = 1304
Score = 62.4 bits (150), Expect = 1e-09
Identities = 78/294 (26%), Positives = 109/294 (37%), Gaps = 28/294 (9%)
Query: 239 SGNLCGTPGGEEPLLLWKAPGPCVQVSYKVWFWVGGRELSPEGITCCCSLIPSGAEWARV 298
S L TPG + + K +K W E+S T L P RV
Sbjct: 662 SVQLSWTPGDDNNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRV 721
Query: 299 SAVNATSWEPLTNLSLVCLDSASAP--RSVAVSSIAGSTE-LLVTWQP-------GPGEP 348
AVN+ + S L AS P AV + + L++TW+P GPG
Sbjct: 722 MAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPG-- 779
Query: 349 LEHVVDWA-RDGDPLEKLNWVRLPPGNLSALLPGNFTVGVPYRITVTAVSASGLASASSV 407
L++ V W +DGD W + N+S + VPY I V A++ G A +V
Sbjct: 780 LQYKVSWRQKDGDD----EWTSVVVANVSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAV 835
Query: 408 -WGFREELAPLVGPTLWRLQDAPPGTPAIAWGEVPRHQLRGHLTHYTLCAQSGTSPS--- 463
G E P+V P R+ + W VP +RGHL Y + S S
Sbjct: 836 VMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRN 895
Query: 464 ------VCMNVSGNTQSVTLPDL-PWGPCELWVTASTIAGQGPPGPILRLHLPD 510
+ G+ LP L P+ L V G+GP P + P+
Sbjct: 896 RRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPE 949
>gi|4504993 leukemia inhibitory factor receptor precursor [Homo
sapiens]
Length = 1097
Score = 55.5 bits (132), Expect = 2e-07
Identities = 59/271 (21%), Positives = 108/271 (39%), Gaps = 33/271 (12%)
Query: 217 WGEWS---PILSFQTPPSAPKDVWVSGNLCGTPGGEEPLLLWKAPGPCVQVSYKVWFWVG 273
W +WS L+ + PS D W + G+ ++ WK P P + + K+ +
Sbjct: 519 WSKWSNKKQHLTTEASPSKGPDTWREWS----SDGKNLIIYWK-PLPINEANGKILSY-- 571
Query: 274 GRELSPEGITCCCSLIPSGAEWARVS-----------AVNATSWEPLTNLSLVCLDSASA 322
S + T S IP A + A N+ P + ++ S
Sbjct: 572 NVSCSSDEETQSLSEIPDPQHKAEIRLDKNDYIISVVAKNSVGSSPPSKIA-----SMEI 626
Query: 323 PRS-VAVSSIAGSTE-LLVTWQPGPGEPLEHVVDWARDG--DPLEKLNWVRLPPGNLSAL 378
P + + + G + +L+TW P ++V+ W +P ++W ++P + +
Sbjct: 627 PNDDLKIEQVVGMGKGILLTWHYDPNMTCDYVIKWCNSSRSEPC-LMDWRKVPSNSTETV 685
Query: 379 LPGN-FTVGVPYRITVTAVSASGLASASSVWGFREELAPLVGPTLWRLQDAPPGTPAIAW 437
+ + F G+ Y + G S+ G+ EELAP+V P + ++D + + W
Sbjct: 686 IESDEFRPGIRYNFFLYGCRNQGYQLLRSMIGYIEELAPIVAPN-FTVEDTSADSILVKW 744
Query: 438 GEVPRHQLRGHLTHYTLCAQSGTSPSVCMNV 468
++P +LRG L Y G + M V
Sbjct: 745 EDIPVEELRGFLRGYLFYFGKGERDTSKMRV 775
>gi|189083786 leukemia inhibitory factor receptor precursor [Homo
sapiens]
Length = 1097
Score = 55.5 bits (132), Expect = 2e-07
Identities = 59/271 (21%), Positives = 108/271 (39%), Gaps = 33/271 (12%)
Query: 217 WGEWS---PILSFQTPPSAPKDVWVSGNLCGTPGGEEPLLLWKAPGPCVQVSYKVWFWVG 273
W +WS L+ + PS D W + G+ ++ WK P P + + K+ +
Sbjct: 519 WSKWSNKKQHLTTEASPSKGPDTWREWS----SDGKNLIIYWK-PLPINEANGKILSY-- 571
Query: 274 GRELSPEGITCCCSLIPSGAEWARVS-----------AVNATSWEPLTNLSLVCLDSASA 322
S + T S IP A + A N+ P + ++ S
Sbjct: 572 NVSCSSDEETQSLSEIPDPQHKAEIRLDKNDYIISVVAKNSVGSSPPSKIA-----SMEI 626
Query: 323 PRS-VAVSSIAGSTE-LLVTWQPGPGEPLEHVVDWARDG--DPLEKLNWVRLPPGNLSAL 378
P + + + G + +L+TW P ++V+ W +P ++W ++P + +
Sbjct: 627 PNDDLKIEQVVGMGKGILLTWHYDPNMTCDYVIKWCNSSRSEPC-LMDWRKVPSNSTETV 685
Query: 379 LPGN-FTVGVPYRITVTAVSASGLASASSVWGFREELAPLVGPTLWRLQDAPPGTPAIAW 437
+ + F G+ Y + G S+ G+ EELAP+V P + ++D + + W
Sbjct: 686 IESDEFRPGIRYNFFLYGCRNQGYQLLRSMIGYIEELAPIVAPN-FTVEDTSADSILVKW 744
Query: 438 GEVPRHQLRGHLTHYTLCAQSGTSPSVCMNV 468
++P +LRG L Y G + M V
Sbjct: 745 EDIPVEELRGFLRGYLFYFGKGERDTSKMRV 775
>gi|222352127 sidekick 2 [Homo sapiens]
Length = 2172
Score = 43.5 bits (101), Expect = 6e-04
Identities = 56/235 (23%), Positives = 97/235 (41%), Gaps = 34/235 (14%)
Query: 297 RVSAVNATSWEPLTNLSLVCLDSA---SAPRSVAVSSIAGSTELLVTWQPGPGEPLE--- 350
R+S NA P + V + A +APR+V V A +T+L VTW+P P +
Sbjct: 1598 RMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHG-ATATQLDVTWEPPPLDSQNGDI 1656
Query: 351 ---HVVDW-ARDGDPLEKLNWVRLPPGNLSALLPGNFTVGVPYRITVTAVSASGLASASS 406
+ W A+ G+ E++ + L ++ N T Y ++V A +A+G S+
Sbjct: 1657 QGYKIYFWEAQRGNLTERVKTLFLAENSVKL---KNLTGYTAYMVSVAAFNAAGDGPRST 1713
Query: 407 VWGFREELAPLVGPTLWRLQDAPPGTPAIAW--GEVPRHQLRGHLTHYTLCAQ-SGTSPS 463
+ + A P+ + + + ++W + P L G+ Y C+ G S
Sbjct: 1714 PTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKI 1773
Query: 464 VCMNVSGNTQ----------------SVTLPDLPWGPCELWVTASTIAGQGPPGP 502
V ++V GN+ + +GP E+ +T G+G PGP
Sbjct: 1774 VTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGP-EIEANVTTGPGEGAPGP 1827
>gi|21536468 AXL receptor tyrosine kinase isoform 2 [Homo sapiens]
Length = 885
Score = 42.4 bits (98), Expect = 0.001
Identities = 64/226 (28%), Positives = 85/226 (37%), Gaps = 34/226 (15%)
Query: 335 TELLVTWQPGPGE--PLEHVVDWA---RDG--------DPLEK--LNWVRLPPGNLSALL 379
TEL V W PG PL H A DG DP E+ + +PP L
Sbjct: 239 TELEVAWTPGLSGIYPLTHCTLQAVLSDDGMGIQAGEPDPPEEPLTSQASVPPHQLRL-- 296
Query: 380 PGNFTVGVPYRITVTAVSASGLASASSVWGFREELAPLVGPTLWRLQDAPPGTPAIAWGE 439
G+ PY I V S+ G +S + +GP + G+ A +
Sbjct: 297 -GSLHPHTPYHIRVACTSSQGPSSWTHWLPVETPEGVPLGPPE-NISATRNGSQAFVHWQ 354
Query: 440 VPRHQLRGHLTHYTLCAQSGTSPSVCMNVSGNTQSVTLP---DLPWGPCELWVTASTIAG 496
PR L+G L Y L Q +P V M++ G Q VTL D + V A T AG
Sbjct: 355 EPRAPLQGTLLGYRLAYQGQDTPEVLMDI-GLRQEVTLELQGDGSVSNLTVCVAAYTAAG 413
Query: 497 QGPPGPILRLHLPDNTLRWKVL-----PGILFLWGLFLLGCGLSLA 537
GP LP W+ + P + W LLG ++ A
Sbjct: 414 DGP------WSLPVPLEAWRPVKEPSTPAFSWPWWYVLLGAVVAAA 453
>gi|21536466 AXL receptor tyrosine kinase isoform 1 [Homo sapiens]
Length = 894
Score = 41.6 bits (96), Expect = 0.002
Identities = 64/232 (27%), Positives = 86/232 (37%), Gaps = 37/232 (15%)
Query: 335 TELLVTWQPGPGE--PLEHVVDWA---RDG--------DPLEK--LNWVRLPPGNLSALL 379
TEL V W PG PL H A DG DP E+ + +PP L
Sbjct: 239 TELEVAWTPGLSGIYPLTHCTLQAVLSDDGMGIQAGEPDPPEEPLTSQASVPPHQLRL-- 296
Query: 380 PGNFTVGVPYRITVTAVSASGLASASSVWGFREELAPLVGPTLWRLQDAPPGTPAIAWGE 439
G+ PY I V S+ G +S + +GP + G+ A +
Sbjct: 297 -GSLHPHTPYHIRVACTSSQGPSSWTHWLPVETPEGVPLGPPE-NISATRNGSQAFVHWQ 354
Query: 440 VPRHQLRGHLTHYTLCAQSGTSPSVCMNVSGNTQSVTLP---DLPWGPCELWVTASTIAG 496
PR L+G L Y L Q +P V M++ G Q VTL D + V A T AG
Sbjct: 355 EPRAPLQGTLLGYRLAYQGQDTPEVLMDI-GLRQEVTLELQGDGSVSNLTVCVAAYTAAG 413
Query: 497 QGP-----------PGPILRLHLPDNTLRWKVLPGILFLWGLFLLGCGLSLA 537
GP PG +H ++ P + W LLG ++ A
Sbjct: 414 DGPWSLPVPLEAWRPGQAQPVH---QLVKEPSTPAFSWPWWYVLLGAVVAAA 462
>gi|28610149 interleukin 6 signal transducer isoform 2 precursor
[Homo sapiens]
Length = 329
Score = 41.2 bits (95), Expect = 0.003
Identities = 27/97 (27%), Positives = 41/97 (42%), Gaps = 1/97 (1%)
Query: 125 QMKPNAPRLGPDVDFSEDDPLEATVHWAPPTWPSHKVLICQFHYRRCQEAAWTLLEPELK 184
++KPN P V SE+ + W P+ S +L YR + W+ + PE
Sbjct: 219 KVKPNPPH-NLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDT 277
Query: 185 TIPLTPVEIQDLELATGYKVYGRCRMEKEEDLWGEWS 221
+ +QDL+ T Y RC E + W +WS
Sbjct: 278 ASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWS 314
>gi|119220552 sidekick 1 [Homo sapiens]
Length = 2213
Score = 40.8 bits (94), Expect = 0.004
Identities = 44/164 (26%), Positives = 67/164 (40%), Gaps = 14/164 (8%)
Query: 320 ASAPRSVAVSSIAGSTELLVTWQPGPGEPLEHVVD------WARDG-DPLEKLNWVRLPP 372
A AP++V V+ + S +L VTW P P E + W D + EK+ + LP
Sbjct: 1702 AMAPQNVQVTPLTAS-QLEVTWDPPPPESQNGNIQGYKIYYWEADSQNETEKMKVLFLPE 1760
Query: 373 GNLSALLPGNFTVGVPYRITVTAVSASGLASASSVWGFREELAPLVGPTLWRLQDAPPGT 432
+ N T Y ++++A +A+G S R A P+ + T
Sbjct: 1761 ---PVVRLKNLTSHTKYLVSISAFNAAGDGPKSDPQQGRTHQAAPGAPSFLAFSEITSTT 1817
Query: 433 PAIAWGE--VPRHQLRGHLTHY-TLCAQSGTSPSVCMNVSGNTQ 473
++WGE L+G+ Y L G S V + V GN Q
Sbjct: 1818 LNVSWGEPAAANGILQGYRVVYEPLAPVQGVSKVVTVEVRGNWQ 1861
Score = 30.4 bits (67), Expect = 5.2
Identities = 41/184 (22%), Positives = 70/184 (38%), Gaps = 10/184 (5%)
Query: 288 LIPSGAEWARVSAVNATS---WEPLTNLSLVCLDSASAPRSVAVSSIAGSTELLVTWQPG 344
L P+ RV AVN + T+ ++ + SAP V+S + ++V WQP
Sbjct: 733 LTPARTYQFRVCAVNEVGRGQYSAETSRLMLPEEPPSAPPKNIVASGRTNQSIMVQWQPP 792
Query: 345 P-----GEPLEHVVDWARDGDPLEKLNWVRLPPGNLSALLPGNFTVGVPYRITVTAVSAS 399
P G +++ + G P E + ++ L + + Y I V A + +
Sbjct: 793 PETEHNGVLRGYILRYRLAGLPGE-YQQRNITSPEVNYCLVTDLIIWTQYEIQVAAYNGA 851
Query: 400 GLASAS-SVWGFREELAPLVGPTLWRLQDAPPGTPAIAWGEVPRHQLRGHLTHYTLCAQS 458
GL S +V + + P P + + T W P+ + G Y L A
Sbjct: 852 GLGVFSRAVTEYTLQGVPTAPPQNVQTEAVNSTTIQFLWNPPPQQFINGINQGYKLLAWP 911
Query: 459 GTSP 462
+P
Sbjct: 912 ADAP 915
>gi|221316760 L1 cell adhesion molecule isoform 3 precursor [Homo
sapiens]
Length = 1248
Score = 39.3 bits (90), Expect = 0.011
Identities = 65/257 (25%), Positives = 96/257 (37%), Gaps = 42/257 (16%)
Query: 297 RVSAVNATSWEPLTNLSLVCLDSASAPRSVAVSSIAG----STELLVTWQP-----GPGE 347
RV+A+N + +S + +AP V + G +T +++TW+P
Sbjct: 683 RVTAINKYGPGEPSPVSETVVTPEAAPEKNPVD-VKGEGNETTNMVITWKPLRWMDWNAP 741
Query: 348 PLEHVVDWARDGDPLEKLNWVRLPPGNLSALLPGNFTVGVPYRITVTAVSASGLASASSV 407
+++ V W G + P L+ N + VPY I V AV++ G V
Sbjct: 742 QVQYRVQWRPQGTRGPWQEQIVSDP----FLVVSNTSTFVPYEIKVQAVNSQGKGPEPQV 797
Query: 408 W-GFREELAPLVGPTLWRLQDAPPGTPAIAWGEVPRHQLRGHLTHYTLCA-QSGTSPSVC 465
G+ E P P L ++ + W V Q++GHL Y + + G+
Sbjct: 798 TIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHS 857
Query: 466 MN--------VSGNTQSVTLPDL-PWGPCELWVTASTIAGQGP------------PGPIL 504
V NT SV L L P+ L V A G GP PG
Sbjct: 858 KRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFTFSTPEGVPGHPE 917
Query: 505 RLHL--PDNT---LRWK 516
LHL NT LRW+
Sbjct: 918 ALHLECQSNTSLLLRWQ 934
>gi|13435353 L1 cell adhesion molecule isoform 2 precursor [Homo
sapiens]
Length = 1253
Score = 39.3 bits (90), Expect = 0.011
Identities = 65/257 (25%), Positives = 96/257 (37%), Gaps = 42/257 (16%)
Query: 297 RVSAVNATSWEPLTNLSLVCLDSASAPRSVAVSSIAG----STELLVTWQP-----GPGE 347
RV+A+N + +S + +AP V + G +T +++TW+P
Sbjct: 688 RVTAINKYGPGEPSPVSETVVTPEAAPEKNPVD-VKGEGNETTNMVITWKPLRWMDWNAP 746
Query: 348 PLEHVVDWARDGDPLEKLNWVRLPPGNLSALLPGNFTVGVPYRITVTAVSASGLASASSV 407
+++ V W G + P L+ N + VPY I V AV++ G V
Sbjct: 747 QVQYRVQWRPQGTRGPWQEQIVSDP----FLVVSNTSTFVPYEIKVQAVNSQGKGPEPQV 802
Query: 408 W-GFREELAPLVGPTLWRLQDAPPGTPAIAWGEVPRHQLRGHLTHYTLCA-QSGTSPSVC 465
G+ E P P L ++ + W V Q++GHL Y + + G+
Sbjct: 803 TIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHS 862
Query: 466 MN--------VSGNTQSVTLPDL-PWGPCELWVTASTIAGQGP------------PGPIL 504
V NT SV L L P+ L V A G GP PG
Sbjct: 863 KRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFTFSTPEGVPGHPE 922
Query: 505 RLHL--PDNT---LRWK 516
LHL NT LRW+
Sbjct: 923 ALHLECQSNTSLLLRWQ 939
>gi|4557707 L1 cell adhesion molecule isoform 1 precursor [Homo
sapiens]
Length = 1257
Score = 39.3 bits (90), Expect = 0.011
Identities = 65/257 (25%), Positives = 96/257 (37%), Gaps = 42/257 (16%)
Query: 297 RVSAVNATSWEPLTNLSLVCLDSASAPRSVAVSSIAG----STELLVTWQP-----GPGE 347
RV+A+N + +S + +AP V + G +T +++TW+P
Sbjct: 688 RVTAINKYGPGEPSPVSETVVTPEAAPEKNPVD-VKGEGNETTNMVITWKPLRWMDWNAP 746
Query: 348 PLEHVVDWARDGDPLEKLNWVRLPPGNLSALLPGNFTVGVPYRITVTAVSASGLASASSV 407
+++ V W G + P L+ N + VPY I V AV++ G V
Sbjct: 747 QVQYRVQWRPQGTRGPWQEQIVSDP----FLVVSNTSTFVPYEIKVQAVNSQGKGPEPQV 802
Query: 408 W-GFREELAPLVGPTLWRLQDAPPGTPAIAWGEVPRHQLRGHLTHYTLCA-QSGTSPSVC 465
G+ E P P L ++ + W V Q++GHL Y + + G+
Sbjct: 803 TIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHS 862
Query: 466 MN--------VSGNTQSVTLPDL-PWGPCELWVTASTIAGQGP------------PGPIL 504
V NT SV L L P+ L V A G GP PG
Sbjct: 863 KRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFTFSTPEGVPGHPE 922
Query: 505 RLHL--PDNT---LRWK 516
LHL NT LRW+
Sbjct: 923 ALHLECQSNTSLLLRWQ 939
>gi|112734845 collagen, type XX, alpha 1 [Homo sapiens]
Length = 1284
Score = 39.3 bits (90), Expect = 0.011
Identities = 42/169 (24%), Positives = 66/169 (39%), Gaps = 12/169 (7%)
Query: 315 VCLDSASAPRSVAVSSIAGSTELLVTWQPGPGEPLEHVVDWARDGDPLEKLNWVRLPPGN 374
V A +P ++++ + G L P L + + W G+ K + + +P GN
Sbjct: 642 VTTKKAPSPSQLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPLGEG--KAHEISVP-GN 698
Query: 375 L-SALLPGNFTVGVPYRITVTAVSASGLASASSVWGFREELAPLVGPTLWRLQDAPPGTP 433
L +A+LPG Y +T+ A G S + P+ L P +
Sbjct: 699 LGTAVLPG-LGRHTEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSL 757
Query: 434 AIAWGEVPRHQLRGHLTHY--TLCAQSGTSPSVCMNVSGNTQSVTLPDL 480
++W G + HY T SG P ++V G VTLPDL
Sbjct: 758 QVSWTPP-----LGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDL 801
Score = 38.1 bits (87), Expect = 0.025
Identities = 36/140 (25%), Positives = 57/140 (40%), Gaps = 21/140 (15%)
Query: 317 LDSASAPRSVAVSSIAGSTELLVTWQPGPGEPLEHVVDW--ARDGDPLEKLNWVRLPPGN 374
LD+ AP S+ +S + S+ + ++W P P PL++++ W +R G P E + G
Sbjct: 374 LDTLPAPTSLVLSQVTSSS-IRLSWTPAPRHPLKYLIVWRASRGGTPREV-----VVEGP 427
Query: 375 LSALLPGNFTVGVPYRITVTAVSASGLASASSVWGFR--EELAPLVGPTLWRLQDAPPGT 432
++ N Y ++V + G+ G R APL P L P T
Sbjct: 428 AASTELHNLASRTEYLVSVFPIYEGGVGE-----GLRGLVTTAPLPPPRALTLAAVTPRT 482
Query: 433 PAIAWGEVPRHQLRGHLTHY 452
+ W Q THY
Sbjct: 483 VHLTW------QPSAGATHY 496
Score = 30.4 bits (67), Expect = 5.2
Identities = 26/91 (28%), Positives = 42/91 (46%), Gaps = 3/91 (3%)
Query: 319 SASAPRSVAVSSIAGSTELLVTWQPGPGEPLEHVVDWARDGDPLEKLNWVRLPPGNLSAL 378
S S P ++A++S + L V+W P G L + + +A L V +P
Sbjct: 740 SRSPPSNLALASETPDS-LQVSWTPPLGRVLHYWLTYA-PASGLGPEKSVSVPGARSHVT 797
Query: 379 LPGNFTVGVPYRITVTAVSASGLASASSVWG 409
LP + YR+ V+A+ A+G + A S G
Sbjct: 798 LP-DLQAATKYRVLVSAIYAAGRSEAVSATG 827
>gi|218505839 interleukin 11 receptor, alpha isoform 1 precursor
[Homo sapiens]
Length = 422
Score = 38.9 bits (89), Expect = 0.015
Identities = 40/150 (26%), Positives = 64/150 (42%), Gaps = 14/150 (9%)
Query: 120 VNLETQMKPNAPRLGPDVDFSEDDPLEATVHWA-PPTWPS--HKVLICQFHYRRCQEAAW 176
V+L++ ++P+ P+ G V+ P W P +WP H +L + YR Q AW
Sbjct: 210 VSLQSILRPDPPQ-GLRVESVPGYPRRLRASWTYPASWPCQPHFLLKFRLQYRPAQHPAW 268
Query: 177 TLLEPE-LKTIPLTPVEIQDLELATGYKVYGRCRMEKEEDLWGEWSPILSFQTPPSA--P 233
+ +EP L+ + I D + V R + W WSP ++ TP + P
Sbjct: 269 STVEPAGLEEV------ITDAVAGLPHAVRVSARDFLDAGTWSTWSP-EAWGTPSTGTIP 321
Query: 234 KDVWVSGNLCGTPGGEEPLLLWKAPGPCVQ 263
K++ G L P E + P P +Q
Sbjct: 322 KEIPAWGQLHTQPEVEPQVDSPAPPRPSLQ 351
>gi|22212922 interleukin 11 receptor, alpha isoform 2 precursor
[Homo sapiens]
Length = 390
Score = 38.9 bits (89), Expect = 0.015
Identities = 40/150 (26%), Positives = 64/150 (42%), Gaps = 14/150 (9%)
Query: 120 VNLETQMKPNAPRLGPDVDFSEDDPLEATVHWA-PPTWPS--HKVLICQFHYRRCQEAAW 176
V+L++ ++P+ P+ G V+ P W P +WP H +L + YR Q AW
Sbjct: 210 VSLQSILRPDPPQ-GLRVESVPGYPRRLRASWTYPASWPCQPHFLLKFRLQYRPAQHPAW 268
Query: 177 TLLEPE-LKTIPLTPVEIQDLELATGYKVYGRCRMEKEEDLWGEWSPILSFQTPPSA--P 233
+ +EP L+ + I D + V R + W WSP ++ TP + P
Sbjct: 269 STVEPAGLEEV------ITDAVAGLPHAVRVSARDFLDAGTWSTWSP-EAWGTPSTGTIP 321
Query: 234 KDVWVSGNLCGTPGGEEPLLLWKAPGPCVQ 263
K++ G L P E + P P +Q
Sbjct: 322 KEIPAWGQLHTQPEVEPQVDSPAPPRPSLQ 351
>gi|4758594 interleukin 11 receptor, alpha isoform 1 precursor [Homo
sapiens]
Length = 422
Score = 38.9 bits (89), Expect = 0.015
Identities = 40/150 (26%), Positives = 64/150 (42%), Gaps = 14/150 (9%)
Query: 120 VNLETQMKPNAPRLGPDVDFSEDDPLEATVHWA-PPTWPS--HKVLICQFHYRRCQEAAW 176
V+L++ ++P+ P+ G V+ P W P +WP H +L + YR Q AW
Sbjct: 210 VSLQSILRPDPPQ-GLRVESVPGYPRRLRASWTYPASWPCQPHFLLKFRLQYRPAQHPAW 268
Query: 177 TLLEPE-LKTIPLTPVEIQDLELATGYKVYGRCRMEKEEDLWGEWSPILSFQTPPSA--P 233
+ +EP L+ + I D + V R + W WSP ++ TP + P
Sbjct: 269 STVEPAGLEEV------ITDAVAGLPHAVRVSARDFLDAGTWSTWSP-EAWGTPSTGTIP 321
Query: 234 KDVWVSGNLCGTPGGEEPLLLWKAPGPCVQ 263
K++ G L P E + P P +Q
Sbjct: 322 KEIPAWGQLHTQPEVEPQVDSPAPPRPSLQ 351
>gi|109633041 protein tyrosine phosphatase, receptor type, F isoform
1 precursor [Homo sapiens]
Length = 1907
Score = 37.7 bits (86), Expect = 0.033
Identities = 42/179 (23%), Positives = 71/179 (39%), Gaps = 11/179 (6%)
Query: 334 STELLVTWQPGPGEPLEHV-VDWARDGD--PLEKLNWVRLPPGNLSALLPGNFTVGVPYR 390
+T + +TW G EP+ + + + G P ++++ V ++ L P + Y
Sbjct: 332 ATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPFQEVDGVATTRYSIGGLSPFS-----EYA 386
Query: 391 ITVTAVSASGLASASSVWGFRE-ELAPLVGPTLWRLQDAPPGTPAIAWG--EVPRHQLRG 447
V AV++ G S R E AP P + + T + W E P +RG
Sbjct: 387 FRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLVRG 446
Query: 448 HLTHYTLCAQSGTSPSVCMNVSGNTQSVTLPDLPWGPCELWVTASTIAGQGPPGPILRL 506
+ +YT ++ + N + LP L V A T G GPP P +++
Sbjct: 447 YRVYYTPDSRRPPNAWHKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQV 505
Score = 29.6 bits (65), Expect = 8.9
Identities = 52/234 (22%), Positives = 80/234 (34%), Gaps = 16/234 (6%)
Query: 282 ITCCCSLIPSGAEWARVSAVNATS-WEPLTNLSLVCLDSASAPRSVAVSSIAGSTELLVT 340
+T SL+P RV A A P + + A + + + T + ++
Sbjct: 472 LTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRIQLS 531
Query: 341 WQPGPGEPL--EHVVDWA-RDGDPLEKLNWVRLPPGNLSALLPGNFTVGVPYRITVTAVS 397
W P E + +V WA D D K+ + L L P YR + A S
Sbjct: 532 WLLPPQERIIMYELVYWAAEDEDQQHKVTFDPTSSYTLEDLKPDTL-----YRFQLAARS 586
Query: 398 ASGLASASSVWGFRE-ELAPLVGPTLWRLQDAPPGTPAIAWGEVPRHQLRGHLTHYTLCA 456
G+ + R + P P T ++W P G +T Y++
Sbjct: 587 DMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAY 646
Query: 457 QSGTSPS----VCMNVSGNTQSVTLPDLP-WGPCELWVTASTIAGQGP-PGPIL 504
++ V +S S L L W +WV A T G GP P+L
Sbjct: 647 EAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVL 700
>gi|109633039 protein tyrosine phosphatase, receptor type, F isoform
2 precursor [Homo sapiens]
Length = 1898
Score = 37.7 bits (86), Expect = 0.033
Identities = 42/179 (23%), Positives = 71/179 (39%), Gaps = 11/179 (6%)
Query: 334 STELLVTWQPGPGEPLEHV-VDWARDGD--PLEKLNWVRLPPGNLSALLPGNFTVGVPYR 390
+T + +TW G EP+ + + + G P ++++ V ++ L P + Y
Sbjct: 332 ATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPFQEVDGVATTRYSIGGLSPFS-----EYA 386
Query: 391 ITVTAVSASGLASASSVWGFRE-ELAPLVGPTLWRLQDAPPGTPAIAWG--EVPRHQLRG 447
V AV++ G S R E AP P + + T + W E P +RG
Sbjct: 387 FRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLVRG 446
Query: 448 HLTHYTLCAQSGTSPSVCMNVSGNTQSVTLPDLPWGPCELWVTASTIAGQGPPGPILRL 506
+ +YT ++ + N + LP L V A T G GPP P +++
Sbjct: 447 YRVYYTPDSRRPPNAWHKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQV 505
Score = 29.6 bits (65), Expect = 8.9
Identities = 52/234 (22%), Positives = 80/234 (34%), Gaps = 16/234 (6%)
Query: 282 ITCCCSLIPSGAEWARVSAVNATS-WEPLTNLSLVCLDSASAPRSVAVSSIAGSTELLVT 340
+T SL+P RV A A P + + A + + + T + ++
Sbjct: 472 LTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRIQLS 531
Query: 341 WQPGPGEPL--EHVVDWA-RDGDPLEKLNWVRLPPGNLSALLPGNFTVGVPYRITVTAVS 397
W P E + +V WA D D K+ + L L P YR + A S
Sbjct: 532 WLLPPQERIIMYELVYWAAEDEDQQHKVTFDPTSSYTLEDLKPDTL-----YRFQLAARS 586
Query: 398 ASGLASASSVWGFRE-ELAPLVGPTLWRLQDAPPGTPAIAWGEVPRHQLRGHLTHYTLCA 456
G+ + R + P P T ++W P G +T Y++
Sbjct: 587 DMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAY 646
Query: 457 QSGTSPS----VCMNVSGNTQSVTLPDLP-WGPCELWVTASTIAGQGP-PGPIL 504
++ V +S S L L W +WV A T G GP P+L
Sbjct: 647 EAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVL 700
>gi|24430212 interleukin 23 receptor precursor [Homo sapiens]
Length = 629
Score = 36.2 bits (82), Expect = 0.095
Identities = 45/209 (21%), Positives = 79/209 (37%), Gaps = 29/209 (13%)
Query: 48 GDLNCSWEP--LGDLGAPSELHLQSQKYRSNKTQTVAVAAGRSWVAIPREQLTMSDKLLV 105
G++ C+W L + +H++S + + + S++ I + L K LV
Sbjct: 140 GNMTCTWNAGKLTYIDTKYVVHVKSLETEEEQQYLTS-----SYINISTDSLQGGKKYLV 194
Query: 106 WGTKA---GQPLWPPVFVNLETQMKPNAPRLGPDVDFSEDDPLEATVHWAPPTWPSHKVL 162
W A G + ++L+ + P+A + S + + ATV W S +
Sbjct: 195 WVQAANALGMEESKQLQIHLDDIVIPSAAVI------SRAETINATVPKTIIYWDSQTTI 248
Query: 163 ---ICQFHYRRCQEAAWTLLEPELKTIPLTPVEIQDLELATGYKVYGRCRMEKEEDLWGE 219
C+ Y+ W + E + + E LE Y RC+ E + W
Sbjct: 249 EKVSCEMRYKATTNQTWNVKEFDTNFTYVQQSEFY-LEPNIKYVFQVRCQ-ETGKRYWQP 306
Query: 220 WSPILSFQTPPSAPK--------DVWVSG 240
WS + +TP + P+ D W SG
Sbjct: 307 WSSLFFHKTPETVPQVTSKAFQHDTWNSG 335
>gi|75709184 contactin 3 [Homo sapiens]
Length = 1028
Score = 35.8 bits (81), Expect = 0.12
Identities = 46/179 (25%), Positives = 63/179 (35%), Gaps = 18/179 (10%)
Query: 335 TELLVTWQPGP-----GEPLEHVVDWARDGDPLEKLNWVRL----PPGNLSALLPGNFTV 385
+EL++TW P P GE +VV + PL W++ P +
Sbjct: 715 SELVITWDPVPEELQNGEGFGYVVAFR----PLGVTTWIQTVVTSPDTPRYVFRNESIVP 770
Query: 386 GVPYRITVTAVSASGLASASSVWG-FREELAPLVGPTLWRLQDAPPGTPAIAWGEVPRHQ 444
PY + V + G S V F E P V P+ ++W +P
Sbjct: 771 YSPYEVKVGVYNNKGEGPFSPVTTVFSAEEEPTVAPSQVSANSLSSSEIEVSWNTIPWKL 830
Query: 445 LRGHLTHYTLCAQSG---TSPSVCMNVSGNTQSVTLPDLPWGPCELW-VTASTIAGQGP 499
GHL Y + +G S M V+GN S L L V A AG GP
Sbjct: 831 SNGHLLGYEVRYWNGGGKEESSSKMKVAGNETSARLRGLKSNLAYYTAVRAYNSAGAGP 889
>gi|18860892 protein tyrosine phosphatase, receptor type, D isoform
3 precursor [Homo sapiens]
Length = 1903
Score = 35.8 bits (81), Expect = 0.12
Identities = 51/192 (26%), Positives = 76/192 (39%), Gaps = 15/192 (7%)
Query: 321 SAPRSVAVSSIAGSTELLVTWQPGPGEPLEHVVD------WARDGDPLEKLNWVRLPPGN 374
SAP + ST +LV+WQP P E ++ A DG+ +K + + P +
Sbjct: 610 SAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAVDGED-DKPHEILGIPSD 668
Query: 375 LSALLPGNFTVGVPYRITVTAVSASGLASAS-SVWGFREELAPLVGPTLWRLQDAPPGTP 433
+ L YRITVTA + G S SV E P P ++ +
Sbjct: 669 TTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSV 728
Query: 434 AIAW-GEVPRH---QLRGHLTHYTLC--AQSGTSPSVCMNVSGNTQSVTLPDL-PWGPCE 486
++W VP Q+RG+ HY + P + + + Q + + L P
Sbjct: 729 KVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQDMIISGLQPETSYS 788
Query: 487 LWVTASTIAGQG 498
L VTA T G G
Sbjct: 789 LTVTAYTTKGDG 800
Score = 33.9 bits (76), Expect = 0.47
Identities = 51/229 (22%), Positives = 93/229 (40%), Gaps = 21/229 (9%)
Query: 312 LSLVCLDSASAPRSVAVSSIAGSTELLVTWQPGPGEPLEHVVDWARDGDPLE---KLNWV 368
++ + + + P V + + +T + +TW G EP+ + + + + E +++ V
Sbjct: 314 IAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVSYYIIQHKPKNSEELYKEIDGV 373
Query: 369 RLPPGNLSALLPGNFTVGVPYRITVTAVSASGLASASS-VWGFREELAPLVGPTLWRLQD 427
+++ L P + Y V AV+ G S V E AP P + +
Sbjct: 374 ATTRYSVAGLSPYS-----DYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARM 428
Query: 428 APPGTPAIAW--GEVPRHQLRGHLTHYTLCAQSGTSPSVCMNVSGNTQSVTLPDL-PWGP 484
T + W E P Q++G+ +YT+ + + NV+ ++Q T+ +L P
Sbjct: 429 LSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVA-DSQITTIGNLVPQKT 487
Query: 485 CELWVTASTIAGQGPPGP----ILRLHLPDNTLRWKVLP----GILFLW 525
+ V A T G GP I + +P L +K P IL W
Sbjct: 488 YSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSW 536
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.137 0.460
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,531,657
Number of Sequences: 37866
Number of extensions: 1935764
Number of successful extensions: 5456
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 85
Number of HSP's that attempted gapping in prelim test: 5168
Number of HSP's gapped (non-prelim): 336
length of query: 636
length of database: 18,247,518
effective HSP length: 109
effective length of query: 527
effective length of database: 14,120,124
effective search space: 7441305348
effective search space used: 7441305348
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.