Guide to the Human Genome
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Search of human proteins with 4759264

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4759264 COP9 constitutive photomorphogenic homolog subunit 2
isoform 1 [Homo sapiens]
         (443 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4759264 COP9 constitutive photomorphogenic homolog subunit 2 ...   888   0.0  
gi|219842262 COP9 constitutive photomorphogenic homolog subunit ...   881   0.0  
gi|28872725 proteasome 26S non-ATPase subunit 11 [Homo sapiens]       114   2e-25
gi|47078240 G protein pathway suppressor 1 isoform 2 [Homo sapiens]    46   8e-05
gi|47078238 G protein pathway suppressor 1 isoform 1 [Homo sapiens]    46   8e-05
gi|4506221 proteasome 26S non-ATPase subunit 12 isoform 1 [Homo ...    41   0.002
gi|28872765 proteasome 26S non-ATPase subunit 12 isoform 2 [Homo...    41   0.002
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho...    39   0.007
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho...    39   0.007
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho...    39   0.007
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho...    39   0.007
gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens]          39   0.009
gi|120432044 vav 3 guanine nucleotide exchange factor isoform 1 ...    36   0.080
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]     35   0.18 
gi|87299626 hypothetical protein LOC283461 [Homo sapiens]              34   0.30 
gi|4503521 eukaryotic translation initiation factor 3, subunit 6...    34   0.30 
gi|116256333 membrane metallo-endopeptidase [Homo sapiens]             33   0.40 
gi|116256331 membrane metallo-endopeptidase [Homo sapiens]             33   0.40 
gi|116256327 membrane metallo-endopeptidase [Homo sapiens]             33   0.40 
gi|116256329 membrane metallo-endopeptidase [Homo sapiens]             33   0.40 
gi|23397429 eukaryotic translation initiation factor 3, subunit ...    33   0.40 
gi|12232385 COP9 constitutive photomorphogenic homolog subunit 7...    33   0.40 
gi|7661914 proteasome (prosome, macropain) 26S subunit, non-ATPa...    33   0.40 
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]               33   0.52 
gi|54607116 leiomodin 3 (fetal) [Homo sapiens]                         33   0.52 
gi|211059431 RANBP2-like and GRIP domain containing 4 [Homo sapi...    32   1.2  
gi|27734905 aprataxin and PNKP like factor [Homo sapiens]              32   1.5  
gi|189217904 RPGRIP1-like isoform b [Homo sapiens]                     32   1.5  
gi|118442834 RPGRIP1-like isoform a [Homo sapiens]                     32   1.5  
gi|46049110 myosin binding protein C, slow type isoform 4 [Homo ...    32   1.5  

>gi|4759264 COP9 constitutive photomorphogenic homolog subunit 2
           isoform 1 [Homo sapiens]
          Length = 443

 Score =  888 bits (2295), Expect = 0.0
 Identities = 443/443 (100%), Positives = 443/443 (100%)

Query: 1   MSDMEDDFMCDDEEDYDLEYSEDSNSEPNVDLENQYYNSKALKEDDPKAALSSFQKVLEL 60
           MSDMEDDFMCDDEEDYDLEYSEDSNSEPNVDLENQYYNSKALKEDDPKAALSSFQKVLEL
Sbjct: 1   MSDMEDDFMCDDEEDYDLEYSEDSNSEPNVDLENQYYNSKALKEDDPKAALSSFQKVLEL 60

Query: 61  EGEKGEWGFKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYIS 120
           EGEKGEWGFKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYIS
Sbjct: 61  EGEKGEWGFKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYIS 120

Query: 121 TSKQMDLLQEFYETTLEALKDAKNDRLWFKTNTKLGKLYLEREEYGKLQKILRQLHQSCQ 180
           TSKQMDLLQEFYETTLEALKDAKNDRLWFKTNTKLGKLYLEREEYGKLQKILRQLHQSCQ
Sbjct: 121 TSKQMDLLQEFYETTLEALKDAKNDRLWFKTNTKLGKLYLEREEYGKLQKILRQLHQSCQ 180

Query: 181 TDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPLIMGVIREC 240
           TDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPLIMGVIREC
Sbjct: 181 TDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPLIMGVIREC 240

Query: 241 GGKMHLREGEFEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGINPFDSQEAK 300
           GGKMHLREGEFEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGINPFDSQEAK
Sbjct: 241 GGKMHLREGEFEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGINPFDSQEAK 300

Query: 301 PYKNDPEILAMTNLVSAYQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRNIRTQVLI 360
           PYKNDPEILAMTNLVSAYQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRNIRTQVLI
Sbjct: 301 PYKNDPEILAMTNLVSAYQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRNIRTQVLI 360

Query: 361 KLIKPYTRIHIPFISKELNIDVADVESLLVQCILDNTIHGRIDQVNQLLELDHQKRGGAR 420
           KLIKPYTRIHIPFISKELNIDVADVESLLVQCILDNTIHGRIDQVNQLLELDHQKRGGAR
Sbjct: 361 KLIKPYTRIHIPFISKELNIDVADVESLLVQCILDNTIHGRIDQVNQLLELDHQKRGGAR 420

Query: 421 YTALDKWTNQLNSLNQAVVSKLA 443
           YTALDKWTNQLNSLNQAVVSKLA
Sbjct: 421 YTALDKWTNQLNSLNQAVVSKLA 443


>gi|219842262 COP9 constitutive photomorphogenic homolog subunit 2
           isoform 2 [Homo sapiens]
          Length = 450

 Score =  881 bits (2277), Expect = 0.0
 Identities = 443/450 (98%), Positives = 443/450 (98%), Gaps = 7/450 (1%)

Query: 1   MSDMEDDFMCDDEEDYDLEYSEDSNSEPNVDLENQYYNSKALKEDDPKAALSSFQKVLEL 60
           MSDMEDDFMCDDEEDYDLEYSEDSNSEPNVDLENQYYNSKALKEDDPKAALSSFQKVLEL
Sbjct: 1   MSDMEDDFMCDDEEDYDLEYSEDSNSEPNVDLENQYYNSKALKEDDPKAALSSFQKVLEL 60

Query: 61  EGEKGEWGFKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYIS 120
           EGEKGEWGFKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYIS
Sbjct: 61  EGEKGEWGFKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYIS 120

Query: 121 TSKQ-------MDLLQEFYETTLEALKDAKNDRLWFKTNTKLGKLYLEREEYGKLQKILR 173
           TSKQ       MDLLQEFYETTLEALKDAKNDRLWFKTNTKLGKLYLEREEYGKLQKILR
Sbjct: 121 TSKQNSDFLCQMDLLQEFYETTLEALKDAKNDRLWFKTNTKLGKLYLEREEYGKLQKILR 180

Query: 174 QLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPLI 233
           QLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPLI
Sbjct: 181 QLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHPLI 240

Query: 234 MGVIRECGGKMHLREGEFEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGINP 293
           MGVIRECGGKMHLREGEFEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGINP
Sbjct: 241 MGVIRECGGKMHLREGEFEKAHTDFFEAFKNYDESGSPRRTTCLKYLVLANMLMKSGINP 300

Query: 294 FDSQEAKPYKNDPEILAMTNLVSAYQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRN 353
           FDSQEAKPYKNDPEILAMTNLVSAYQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRN
Sbjct: 301 FDSQEAKPYKNDPEILAMTNLVSAYQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRN 360

Query: 354 IRTQVLIKLIKPYTRIHIPFISKELNIDVADVESLLVQCILDNTIHGRIDQVNQLLELDH 413
           IRTQVLIKLIKPYTRIHIPFISKELNIDVADVESLLVQCILDNTIHGRIDQVNQLLELDH
Sbjct: 361 IRTQVLIKLIKPYTRIHIPFISKELNIDVADVESLLVQCILDNTIHGRIDQVNQLLELDH 420

Query: 414 QKRGGARYTALDKWTNQLNSLNQAVVSKLA 443
           QKRGGARYTALDKWTNQLNSLNQAVVSKLA
Sbjct: 421 QKRGGARYTALDKWTNQLNSLNQAVVSKLA 450


>gi|28872725 proteasome 26S non-ATPase subunit 11 [Homo sapiens]
          Length = 422

 Score =  114 bits (284), Expect = 2e-25
 Identities = 90/325 (27%), Positives = 157/325 (48%), Gaps = 28/325 (8%)

Query: 95  LLTYIR---SAVTRNYSEKSINSILDYI-----STSKQMDLLQEFYETTLEALKDAKNDR 146
           LL Y+R   +++++  + + + S+LD       +T ++++L  E     +E  K  K   
Sbjct: 69  LLKYVRPFLNSISKAKAARLVRSLLDLFLDMEAATGQEVELCLE----CIEWAKSEKRTF 124

Query: 147 LWFKTNTKLGKLYLEREEYGKLQKILRQLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYT 206
           L      +L  LY + + Y +   +  QL +  +  D +        L+E+  LE + Y 
Sbjct: 125 LRQALEARLVSLYFDTKRYQEALHLGSQLLRELKKMDDK------ALLVEVQLLESKTYH 178

Query: 207 AQKNNKKLKALYEQSLHIKSAIP-HPLIMGVIRECGGKMHL-REGEFEKAHTDFFEAFKN 264
           A  N  K +A    +    +AI   P +   +    G +H   E +++ A++ F+EAF+ 
Sbjct: 179 ALSNLPKARAALTSARTTANAIYCPPKLQATLDMQSGIIHAAEEKDWKTAYSYFYEAFEG 238

Query: 265 YDESGSPRRTTCLKYLVLANMLMKSGINPFDSQEAKPYK-----NDPEILAMTNLVSAYQ 319
           YD   SP+  T LKY++L  +++ +   P D Q     K        +  A+  +  A +
Sbjct: 239 YDSIDSPKAITSLKYMLLCKIMLNT---PEDVQALVSGKLALRYAGRQTEALKCVAQASK 295

Query: 320 NNDITEFEKILKTNHSNIMDDPFIREHIEELLRNIRTQVLIKLIKPYTRIHIPFISKELN 379
           N  + +FEK L    + + DDP I  H+ +L  N+  Q LI++I+P++R+ I  IS  + 
Sbjct: 296 NRSLADFEKALTDYRAELRDDPIISTHLAKLYDNLLEQNLIRVIEPFSRVQIEHISSLIK 355

Query: 380 IDVADVESLLVQCILDNTIHGRIDQ 404
           +  ADVE  L Q ILD   HG +DQ
Sbjct: 356 LSKADVERKLSQMILDKKFHGILDQ 380


>gi|47078240 G protein pathway suppressor 1 isoform 2 [Homo sapiens]
          Length = 491

 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 24/82 (29%), Positives = 41/82 (50%)

Query: 328 KILKTNHSNIMDDPFIREHIEELLRNIRTQVLIKLIKPYTRIHIPFISKELNIDVADVES 387
           K+L     N++ D ++  H+  L   IR + LI+   PY    +  ++   N  VA +E 
Sbjct: 343 KMLDEMKDNLLLDMYLAPHVRTLYTQIRNRALIQYFSPYVSADMHRMAAAFNTTVAALED 402

Query: 388 LLVQCILDNTIHGRIDQVNQLL 409
            L Q IL+  I  R+D  +++L
Sbjct: 403 ELTQLILEGLISARVDSHSKIL 424


>gi|47078238 G protein pathway suppressor 1 isoform 1 [Homo sapiens]
          Length = 527

 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 24/82 (29%), Positives = 41/82 (50%)

Query: 328 KILKTNHSNIMDDPFIREHIEELLRNIRTQVLIKLIKPYTRIHIPFISKELNIDVADVES 387
           K+L     N++ D ++  H+  L   IR + LI+   PY    +  ++   N  VA +E 
Sbjct: 379 KMLDEMKDNLLLDMYLAPHVRTLYTQIRNRALIQYFSPYVSADMHRMAAAFNTTVAALED 438

Query: 388 LLVQCILDNTIHGRIDQVNQLL 409
            L Q IL+  I  R+D  +++L
Sbjct: 439 ELTQLILEGLISARVDSHSKIL 460


>gi|4506221 proteasome 26S non-ATPase subunit 12 isoform 1 [Homo
           sapiens]
          Length = 456

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 56/319 (17%), Positives = 137/319 (42%), Gaps = 49/319 (15%)

Query: 156 GKLYLEREEYGKLQKILRQLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLK 215
           GK+Y+E E   +L K L  + +         D+K+   +L+   L+++ Y + +  ++++
Sbjct: 134 GKIYVEIER-ARLTKTLATIKEQ------NGDVKEAASILQ--ELQVETYGSMEKKERVE 184

Query: 216 ALYEQSLHIKSAIPHPLIMGVIRECGGKMHLREGEFEKAHTDFFEAFKNYDESGSPRRTT 275
            + EQ + +  A+   +   +I +       +E   EK    ++      D+      + 
Sbjct: 185 FILEQ-MRLCLAVKDYIRTQIISKKINTKFFQEENTEKLKLKYYNLMIQLDQHEGSYLSI 243

Query: 276 CLKYLV-----------------LANMLMKSGINPFDSQEAKPY------KNDPEILAMT 312
           C  Y                   L ++++   + PFD++++         K   EI    
Sbjct: 244 CKHYRAIYDTPCIQAESEKWQQALKSVVLYVILAPFDNEQSDLVHRISGDKKLEEIPKYK 303

Query: 313 NLVSAYQNNDITEFEKILKTNHSNI----MDDPFI-----REHIEELLRNIRTQVL---I 360
           +L+  +   ++  +  +++     +    ++ P        E  E+  ++++ +V+   I
Sbjct: 304 DLLKLFTTMELMRWSTLVEDYGMELRKGSLESPATDVFGSTEEGEKRWKDLKNRVVEHNI 363

Query: 361 KLI-KPYTRIHIPFISKELNIDVADVESLLVQCILDNTIHGRIDQVNQLLELDHQKRGGA 419
           +++ K YTRI +  +++ L++ V + E+ L   +++ TI  ++D++  ++     K    
Sbjct: 364 RIMAKYYTRITMKRMAQLLDLSVDESEAFLSNLVVNKTIFAKVDRLAGIINFQRPKDPN- 422

Query: 420 RYTALDKWTNQLNSLNQAV 438
               L+ W+ +LNSL   V
Sbjct: 423 --NLLNDWSQKLNSLMSLV 439


>gi|28872765 proteasome 26S non-ATPase subunit 12 isoform 2 [Homo
           sapiens]
          Length = 436

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 56/319 (17%), Positives = 137/319 (42%), Gaps = 49/319 (15%)

Query: 156 GKLYLEREEYGKLQKILRQLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLK 215
           GK+Y+E E   +L K L  + +         D+K+   +L+   L+++ Y + +  ++++
Sbjct: 114 GKIYVEIER-ARLTKTLATIKEQ------NGDVKEAASILQ--ELQVETYGSMEKKERVE 164

Query: 216 ALYEQSLHIKSAIPHPLIMGVIRECGGKMHLREGEFEKAHTDFFEAFKNYDESGSPRRTT 275
            + EQ + +  A+   +   +I +       +E   EK    ++      D+      + 
Sbjct: 165 FILEQ-MRLCLAVKDYIRTQIISKKINTKFFQEENTEKLKLKYYNLMIQLDQHEGSYLSI 223

Query: 276 CLKYLV-----------------LANMLMKSGINPFDSQEAKPY------KNDPEILAMT 312
           C  Y                   L ++++   + PFD++++         K   EI    
Sbjct: 224 CKHYRAIYDTPCIQAESEKWQQALKSVVLYVILAPFDNEQSDLVHRISGDKKLEEIPKYK 283

Query: 313 NLVSAYQNNDITEFEKILKTNHSNI----MDDPFI-----REHIEELLRNIRTQVL---I 360
           +L+  +   ++  +  +++     +    ++ P        E  E+  ++++ +V+   I
Sbjct: 284 DLLKLFTTMELMRWSTLVEDYGMELRKGSLESPATDVFGSTEEGEKRWKDLKNRVVEHNI 343

Query: 361 KLI-KPYTRIHIPFISKELNIDVADVESLLVQCILDNTIHGRIDQVNQLLELDHQKRGGA 419
           +++ K YTRI +  +++ L++ V + E+ L   +++ TI  ++D++  ++     K    
Sbjct: 344 RIMAKYYTRITMKRMAQLLDLSVDESEAFLSNLVVNKTIFAKVDRLAGIINFQRPKDPN- 402

Query: 420 RYTALDKWTNQLNSLNQAV 438
               L+ W+ +LNSL   V
Sbjct: 403 --NLLNDWSQKLNSLMSLV 419


>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
            sapiens]
          Length = 1972

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 52/231 (22%), Positives = 95/231 (41%), Gaps = 27/231 (11%)

Query: 17   DLEYSEDSNSEPNVDLENQYYNSKALKEDD---------PKAALSSFQKVLELEGEKGEW 67
            DL+  ++ N E    L+ Q +  +   ED+          K  L    K LEL+ +    
Sbjct: 1579 DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIK 1638

Query: 68   G-FKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYISTSKQMD 126
            G  +A+KQ+ K+  ++ +F   +   +     I +    N  EK   S+         + 
Sbjct: 1639 GREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKEN--EKKAKSL------EADLM 1690

Query: 127  LLQEFYETTLEALK--DAKNDRLWFKTNTKLGKLYLEREEYGKLQKILRQLHQSCQTDDG 184
             LQE       A K  D + + L  +  + L      ++E  +L+  + QL +  + + G
Sbjct: 1691 QLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQG 1750

Query: 185  -----EDDLKKGTQLLEIYALEI--QMYTAQKNNKKLKALYEQSLHIKSAI 228
                  D ++K TQ  E  + E+  +  TAQKN    + L  Q+  ++S +
Sbjct: 1751 NMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKL 1801


>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
            sapiens]
          Length = 1979

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 52/231 (22%), Positives = 95/231 (41%), Gaps = 27/231 (11%)

Query: 17   DLEYSEDSNSEPNVDLENQYYNSKALKEDD---------PKAALSSFQKVLELEGEKGEW 67
            DL+  ++ N E    L+ Q +  +   ED+          K  L    K LEL+ +    
Sbjct: 1586 DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIK 1645

Query: 68   G-FKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYISTSKQMD 126
            G  +A+KQ+ K+  ++ +F   +   +     I +    N  EK   S+         + 
Sbjct: 1646 GREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKEN--EKKAKSL------EADLM 1697

Query: 127  LLQEFYETTLEALK--DAKNDRLWFKTNTKLGKLYLEREEYGKLQKILRQLHQSCQTDDG 184
             LQE       A K  D + + L  +  + L      ++E  +L+  + QL +  + + G
Sbjct: 1698 QLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQG 1757

Query: 185  -----EDDLKKGTQLLEIYALEI--QMYTAQKNNKKLKALYEQSLHIKSAI 228
                  D ++K TQ  E  + E+  +  TAQKN    + L  Q+  ++S +
Sbjct: 1758 NMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKL 1808


>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
            sapiens]
          Length = 1945

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 52/231 (22%), Positives = 95/231 (41%), Gaps = 27/231 (11%)

Query: 17   DLEYSEDSNSEPNVDLENQYYNSKALKEDD---------PKAALSSFQKVLELEGEKGEW 67
            DL+  ++ N E    L+ Q +  +   ED+          K  L    K LEL+ +    
Sbjct: 1586 DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIK 1645

Query: 68   G-FKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYISTSKQMD 126
            G  +A+KQ+ K+  ++ +F   +   +     I +    N  EK   S+         + 
Sbjct: 1646 GREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKEN--EKKAKSL------EADLM 1697

Query: 127  LLQEFYETTLEALK--DAKNDRLWFKTNTKLGKLYLEREEYGKLQKILRQLHQSCQTDDG 184
             LQE       A K  D + + L  +  + L      ++E  +L+  + QL +  + + G
Sbjct: 1698 QLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQG 1757

Query: 185  -----EDDLKKGTQLLEIYALEI--QMYTAQKNNKKLKALYEQSLHIKSAI 228
                  D ++K TQ  E  + E+  +  TAQKN    + L  Q+  ++S +
Sbjct: 1758 NMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKL 1808


>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
            sapiens]
          Length = 1938

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 52/231 (22%), Positives = 95/231 (41%), Gaps = 27/231 (11%)

Query: 17   DLEYSEDSNSEPNVDLENQYYNSKALKEDD---------PKAALSSFQKVLELEGEKGEW 67
            DL+  ++ N E    L+ Q +  +   ED+          K  L    K LEL+ +    
Sbjct: 1579 DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIK 1638

Query: 68   G-FKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYISTSKQMD 126
            G  +A+KQ+ K+  ++ +F   +   +     I +    N  EK   S+         + 
Sbjct: 1639 GREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKEN--EKKAKSL------EADLM 1690

Query: 127  LLQEFYETTLEALK--DAKNDRLWFKTNTKLGKLYLEREEYGKLQKILRQLHQSCQTDDG 184
             LQE       A K  D + + L  +  + L      ++E  +L+  + QL +  + + G
Sbjct: 1691 QLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQG 1750

Query: 185  -----EDDLKKGTQLLEIYALEI--QMYTAQKNNKKLKALYEQSLHIKSAI 228
                  D ++K TQ  E  + E+  +  TAQKN    + L  Q+  ++S +
Sbjct: 1751 NMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKL 1801


>gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens]
          Length = 4646

 Score = 38.9 bits (89), Expect = 0.009
 Identities = 40/169 (23%), Positives = 75/169 (44%), Gaps = 20/169 (11%)

Query: 108 SEKSINSILDYISTSKQMDLLQEFYET-----TLEALKDAK--NDRLWFKTNTKLGKLYL 160
           S  ++  I  +++  + +  +QE  E+     TL+ LK  K  +  + F T+T L +   
Sbjct: 268 SGTALQEISFWLNLERALYRIQEKRESPEVLLTLDILKHGKRFHATVSFDTDTGLKQALE 327

Query: 161 EREEYGKLQKILRQLHQSCQTDDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQ 220
              +Y  L K           D   +DL   T+L +I    + ++T  +  +  K   ++
Sbjct: 328 TVNDYNPLMK-----------DFPLNDLLSATELDKIRQALVAIFTHLRKIRNTKYPIQR 376

Query: 221 SLHIKSAIPHPLIMGVIRECGGK--MHLREGEFEKAHTDFFEAFKNYDE 267
           +L +  AI   L   +++  G +  MH+   EFEK     FE F+ +D+
Sbjct: 377 ALRLVEAISRDLSSQLLKVLGTRKLMHVAYEEFEKVMVACFEVFQTWDD 425


>gi|120432044 vav 3 guanine nucleotide exchange factor isoform 1
           [Homo sapiens]
          Length = 847

 Score = 35.8 bits (81), Expect = 0.080
 Identities = 38/157 (24%), Positives = 64/157 (40%), Gaps = 33/157 (21%)

Query: 1   MSDMEDDFMCDDEED-YDLEYSEDSNSEPNVDL--ENQYYNSKALKEDDPKAALSSFQKV 57
           + D+ D+ + +DEED YD  Y ED   E   DL    + +  K  + D     L+  ++ 
Sbjct: 144 LPDLIDETLVEDEEDLYDCVYGEDEGGEVYEDLMKAEEAHQPKCPENDIRSCCLAEIKQT 203

Query: 58  LELEGEKGE----WGFKALKQMI---KINFKLTNFPEMMNRYKQLLTYIRSAVTR----- 105
            E   E  E    +    LK+ +   + +    N PE++  ++ L+  I  ++       
Sbjct: 204 EEKYTETLESIEKYFMAPLKRFLTAAEFDSVFINIPELVKLHRNLMQEIHDSIVNKNDQN 263

Query: 106 ------NYSEK------------SINSILDYISTSKQ 124
                 NY E+            S  S LDYIS +K+
Sbjct: 264 LYQVFINYKERLVIYGQYCSGVESAISSLDYISKTKE 300


>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
          Length = 1979

 Score = 34.7 bits (78), Expect = 0.18
 Identities = 61/256 (23%), Positives = 111/256 (43%), Gaps = 36/256 (14%)

Query: 32   LENQYYNSKALKEDDPKAALSSFQKVLELEGEKGEWGFKALKQMIKINFKLTNFPEMMNR 91
            LE +  + + + ED  ++ +   Q + E + E  E+ ++  +QM   + +L  F E    
Sbjct: 908  LEEEIKHHQKIIEDQNQSKMQLLQSLQEQKKEMDEFRYQH-EQMNATHTQL--FLEKDEE 964

Query: 92   YKQLLTYIRSAVTRNYSEK----SINS---------ILDYISTSKQMDLLQEFYETTLEA 138
             K L   I    T+ + E+    + NS          L+  + S++ DL +   E  ++ 
Sbjct: 965  IKSLQKTIEQIKTQLHEERQDIQTDNSDIFQETKVQSLNIENGSEKHDLSKAETERLVKG 1024

Query: 139  LKDAKND-RLWFKTNTKLGKLY--LEREEYGKLQKILRQ-------LHQSCQTDDGEDDL 188
            +K+ + + +L  + N  L K    L ++E GKL +I++Q       LH    +     D+
Sbjct: 1025 IKERELEIKLLNEKNISLTKQIDQLSKDEVGKLTQIIQQKDLEIQALHARISSTSHTQDV 1084

Query: 189  KKGTQLLEIYALEIQMYTAQKN-----NKKLKALYEQSLHIKSAIPHPLIMGVIRECGGK 243
                Q L+ YA+E +   A  N     N  LK  Y + + I +A    LI   +++   K
Sbjct: 1085 VYLQQQLQAYAMEREKVFAVLNEKTRENSHLKTEYHKMMDIVAAKEAALIK--LQDENKK 1142

Query: 244  MHLREGEFEKAHTDFF 259
            +  R   FE +  D F
Sbjct: 1143 LSTR---FESSGQDMF 1155


>gi|87299626 hypothetical protein LOC283461 [Homo sapiens]
          Length = 652

 Score = 33.9 bits (76), Expect = 0.30
 Identities = 35/168 (20%), Positives = 69/168 (41%), Gaps = 22/168 (13%)

Query: 10  CDDEEDYDLEYSEDSNSEPNVDLENQYYNSKALKED------DPKAALSSFQKV------ 57
           C   + Y  EY+++  ++ +   EN YY S + +++        K    S QK       
Sbjct: 371 CQPNKKYQREYNKNERNDLSTSFENDYYPSSSERKEKFENDYQEKTPQKSIQKYPANSMG 430

Query: 58  ---LELEGEKGEWGFKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINS 114
               E    K  W F   + +++     +   + ++  K  L   +S+ + +YS +  +S
Sbjct: 431 NIPSEELHSKQSWDFGLDEILMEEGGIYSLKSKRISTKKISLDSAQSSRSTSYSPRPTDS 490

Query: 115 ILDYISTSKQMDLLQEFYETTLEALKDAKNDRLWFKTNTKLGKLYLER 162
                  S   DL  E  +   + ++D  ++R+  KT  K+   Y+ER
Sbjct: 491 CF-----SSSSDLPSEDEDQISQQIED--SNRMTIKTKEKMNNFYVER 531


>gi|4503521 eukaryotic translation initiation factor 3, subunit 6
           48kDa [Homo sapiens]
          Length = 445

 Score = 33.9 bits (76), Expect = 0.30
 Identities = 28/108 (25%), Positives = 51/108 (47%), Gaps = 6/108 (5%)

Query: 297 QEAKPYKNDPEILAMTNLVSA-YQNNDITEFEKILKTNHSNIMDDPFIREHIEELLRNIR 355
           QE+  YK DP    +T  V   Y N D    +K L+   S +++D F+   +E+ + N R
Sbjct: 283 QESYTYK-DP----ITEFVECLYVNFDFDGAQKKLRECESVLVNDFFLVACLEDFIENAR 337

Query: 356 TQVLIKLIKPYTRIHIPFISKELNIDVADVESLLVQCILDNTIHGRID 403
             +     + +  I I  ++ +LN+   + E  +V  I +  +  +ID
Sbjct: 338 LFIFETFCRIHQCISINMLADKLNMTPEEAERWIVNLIRNARLDAKID 385


>gi|116256333 membrane metallo-endopeptidase [Homo sapiens]
          Length = 750

 Score = 33.5 bits (75), Expect = 0.40
 Identities = 46/224 (20%), Positives = 90/224 (40%), Gaps = 39/224 (17%)

Query: 30  VDLENQYYNSKALKED--DP-----KAALSSFQK--VLELEGEKGEWGFKALKQMIKINF 80
           ++LE +  N+ A  ED  DP     K  L+  Q    LE+ G+   W     + M  +N 
Sbjct: 277 MELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNI 336

Query: 81  KLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYISTSKQMDLLQEFYETTLEALK 140
            +TN  +++    + LT ++  +T+ YS + + +++ +      +  L   Y+ +  A +
Sbjct: 337 SITNEEDVVVYAPEYLTKLKPILTK-YSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFR 395

Query: 141 DA-----KNDRLWFK--------TNTKLGKLYLEREEYGKLQKILRQLHQSCQTDDGEDD 187
            A          W +            +G+LY+E    G+ + ++  L            
Sbjct: 396 KALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLI----------- 444

Query: 188 LKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHP 231
                Q+ E++   +   T      K +A  E++L IK  I +P
Sbjct: 445 ----AQIREVFIQTLDDLTWMDAETKKRA-EEKALAIKERIGYP 483


>gi|116256331 membrane metallo-endopeptidase [Homo sapiens]
          Length = 750

 Score = 33.5 bits (75), Expect = 0.40
 Identities = 46/224 (20%), Positives = 90/224 (40%), Gaps = 39/224 (17%)

Query: 30  VDLENQYYNSKALKED--DP-----KAALSSFQK--VLELEGEKGEWGFKALKQMIKINF 80
           ++LE +  N+ A  ED  DP     K  L+  Q    LE+ G+   W     + M  +N 
Sbjct: 277 MELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNI 336

Query: 81  KLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYISTSKQMDLLQEFYETTLEALK 140
            +TN  +++    + LT ++  +T+ YS + + +++ +      +  L   Y+ +  A +
Sbjct: 337 SITNEEDVVVYAPEYLTKLKPILTK-YSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFR 395

Query: 141 DA-----KNDRLWFK--------TNTKLGKLYLEREEYGKLQKILRQLHQSCQTDDGEDD 187
            A          W +            +G+LY+E    G+ + ++  L            
Sbjct: 396 KALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLI----------- 444

Query: 188 LKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHP 231
                Q+ E++   +   T      K +A  E++L IK  I +P
Sbjct: 445 ----AQIREVFIQTLDDLTWMDAETKKRA-EEKALAIKERIGYP 483


>gi|116256327 membrane metallo-endopeptidase [Homo sapiens]
          Length = 750

 Score = 33.5 bits (75), Expect = 0.40
 Identities = 46/224 (20%), Positives = 90/224 (40%), Gaps = 39/224 (17%)

Query: 30  VDLENQYYNSKALKED--DP-----KAALSSFQK--VLELEGEKGEWGFKALKQMIKINF 80
           ++LE +  N+ A  ED  DP     K  L+  Q    LE+ G+   W     + M  +N 
Sbjct: 277 MELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNI 336

Query: 81  KLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYISTSKQMDLLQEFYETTLEALK 140
            +TN  +++    + LT ++  +T+ YS + + +++ +      +  L   Y+ +  A +
Sbjct: 337 SITNEEDVVVYAPEYLTKLKPILTK-YSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFR 395

Query: 141 DA-----KNDRLWFK--------TNTKLGKLYLEREEYGKLQKILRQLHQSCQTDDGEDD 187
            A          W +            +G+LY+E    G+ + ++  L            
Sbjct: 396 KALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLI----------- 444

Query: 188 LKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHP 231
                Q+ E++   +   T      K +A  E++L IK  I +P
Sbjct: 445 ----AQIREVFIQTLDDLTWMDAETKKRA-EEKALAIKERIGYP 483


>gi|116256329 membrane metallo-endopeptidase [Homo sapiens]
          Length = 750

 Score = 33.5 bits (75), Expect = 0.40
 Identities = 46/224 (20%), Positives = 90/224 (40%), Gaps = 39/224 (17%)

Query: 30  VDLENQYYNSKALKED--DP-----KAALSSFQK--VLELEGEKGEWGFKALKQMIKINF 80
           ++LE +  N+ A  ED  DP     K  L+  Q    LE+ G+   W     + M  +N 
Sbjct: 277 MELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNI 336

Query: 81  KLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYISTSKQMDLLQEFYETTLEALK 140
            +TN  +++    + LT ++  +T+ YS + + +++ +      +  L   Y+ +  A +
Sbjct: 337 SITNEEDVVVYAPEYLTKLKPILTK-YSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFR 395

Query: 141 DA-----KNDRLWFK--------TNTKLGKLYLEREEYGKLQKILRQLHQSCQTDDGEDD 187
            A          W +            +G+LY+E    G+ + ++  L            
Sbjct: 396 KALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLI----------- 444

Query: 188 LKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSAIPHP 231
                Q+ E++   +   T      K +A  E++L IK  I +P
Sbjct: 445 ----AQIREVFIQTLDDLTWMDAETKKRA-EEKALAIKERIGYP 483


>gi|23397429 eukaryotic translation initiation factor 3, subunit M
           [Homo sapiens]
          Length = 374

 Score = 33.5 bits (75), Expect = 0.40
 Identities = 19/100 (19%), Positives = 44/100 (44%), Gaps = 7/100 (7%)

Query: 348 EELLRNIRTQVLIKLIKPYTRIHIPFISKELNIDVADVESLLVQCILDNTIHGRIDQVNQ 407
           E+ +  +R    + +      I    + +EL I   DVE+ ++  +    ++ +IDQ  +
Sbjct: 271 EQNMAKMRLLTFMGMAVENKEISFDTMQQELQIGADDVEAFVIDAVRTKMVYCKIDQTQR 330

Query: 408 LLELDH-------QKRGGARYTALDKWTNQLNSLNQAVVS 440
            + + H       +++    Y  L+ W   LN +  +++S
Sbjct: 331 KVVVSHSTHRTFGKQQWQQLYDTLNAWKQNLNKVKNSLLS 370


>gi|12232385 COP9 constitutive photomorphogenic homolog subunit 7B
           [Homo sapiens]
          Length = 264

 Score = 33.5 bits (75), Expect = 0.40
 Identities = 16/45 (35%), Positives = 32/45 (71%), Gaps = 3/45 (6%)

Query: 371 IPF--ISKELNI-DVADVESLLVQCILDNTIHGRIDQVNQLLELD 412
           IP+  + K+L + ++ ++E L+++ +  + I G++DQ NQLLE+D
Sbjct: 111 IPYSVLLKDLEMRNLRELEDLIIEAVYTDIIQGKLDQRNQLLEVD 155


>gi|7661914 proteasome (prosome, macropain) 26S subunit, non-ATPase,
           6 [Homo sapiens]
          Length = 389

 Score = 33.5 bits (75), Expect = 0.40
 Identities = 17/85 (20%), Positives = 40/85 (47%)

Query: 326 FEKILKTNHSNIMDDPFIREHIEELLRNIRTQVLIKLIKPYTRIHIPFISKELNIDVADV 385
           F + L      +  D     H    +R +R     +L++ Y  + + ++++   + V  +
Sbjct: 271 FFQSLAVVEQEMKKDWLFAPHYRYYVREMRIHAYSQLLESYRSLTLGYMAEAFGVGVEFI 330

Query: 386 ESLLVQCILDNTIHGRIDQVNQLLE 410
           +  L + I    +H +ID+VN+++E
Sbjct: 331 DQELSRFIAAGRLHCKIDKVNEIVE 355


>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
          Length = 1946

 Score = 33.1 bits (74), Expect = 0.52
 Identities = 59/226 (26%), Positives = 103/226 (45%), Gaps = 23/226 (10%)

Query: 12   DEEDYDLEYSEDSNSEPNVDLENQYYNSKALKEDDPKAALSSFQKVLELEGEKG-----E 66
            + E + LE +   N E    +EN   + + L E+  K  L   Q   ++E EKG     +
Sbjct: 1061 ERELHKLEGNLKLNRE---SMENLESSQRHLAEELRKKELELSQMNSKVENEKGLVAQLQ 1117

Query: 67   WGFKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYISTSKQMD 126
               K L+  IK + K     E   R K  +   R+ +T++ ++  +N  L+ +  S    
Sbjct: 1118 KTVKELQTQIK-DLKEKLEAERTTRAK--MERERADLTQDLAD--LNERLEEVGGSSLAQ 1172

Query: 127  L-LQEFYETTLEAL-KDAKNDRLWFKTNT-KLGKLYLER--EEYGKLQKILRQLHQSCQT 181
            L + +  ET  + L +D +   L F+T +  L K + +   E  G+++  L+Q+ Q  + 
Sbjct: 1173 LEITKKQETKFQKLHRDMEEATLHFETTSASLKKRHADSLAELEGQVEN-LQQVKQKLEK 1231

Query: 182  DDGEDDLKKGTQLLEIYALEIQMYTAQKNNKKLKALYEQSLHIKSA 227
            D  +  L+    L  +     QM  A+ N +KL  LYE+ LH  +A
Sbjct: 1232 DKSDLQLEVDDLLTRVE----QMTRAKANAEKLCTLYEERLHEATA 1273


>gi|54607116 leiomodin 3 (fetal) [Homo sapiens]
          Length = 560

 Score = 33.1 bits (74), Expect = 0.52
 Identities = 33/138 (23%), Positives = 59/138 (42%), Gaps = 11/138 (7%)

Query: 5   EDDFMCDDEEDYDLEYSEDSNSEP---------NVDLENQYYNSKALKE--DDPKAALSS 53
           E+D   DDE + D E SE++N E          N +   Q    KA KE  D P+A   S
Sbjct: 150 EEDDDDDDEGEDDGEESEETNREEEGKAKEQIRNCENNCQQVTDKAFKEQRDRPEAQEQS 209

Query: 54  FQKVLELEGEKGEWGFKALKQMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSIN 113
            +K+ +L+ +K       LK   + +   T+    + R ++    ++     N       
Sbjct: 210 EKKISKLDPKKLALDTSFLKVSTRPSGNQTDLDGSLRRVRKNDPDMKELNLNNIENIPKE 269

Query: 114 SILDYISTSKQMDLLQEF 131
            +LD+++  K+   ++ F
Sbjct: 270 MLLDFVNAMKKNKHIKTF 287


>gi|211059431 RANBP2-like and GRIP domain containing 4 [Homo sapiens]
          Length = 1758

 Score = 32.0 bits (71), Expect = 1.2
 Identities = 20/85 (23%), Positives = 39/85 (45%), Gaps = 2/85 (2%)

Query: 12   DEEDYDLEYSEDSNSEPNVDLENQYYNSKALKEDDPKAALSSFQKVLELEGEKGEWGFKA 71
            D++ Y  E S+D + EP V +  +      + E+  K   S   K+   + E  +W  + 
Sbjct: 1024 DDDAYKTEDSDDIHFEPVVQMPEKV--ELVIGEEGEKVLYSQGVKLFRFDAEVRQWKERG 1081

Query: 72   LKQMIKINFKLTNFPEMMNRYKQLL 96
            L  +  +  ++   P M+ R +Q+L
Sbjct: 1082 LGNLKILKNEVNGKPRMLMRREQVL 1106


>gi|27734905 aprataxin and PNKP like factor [Homo sapiens]
          Length = 511

 Score = 31.6 bits (70), Expect = 1.5
 Identities = 17/42 (40%), Positives = 25/42 (59%), Gaps = 1/42 (2%)

Query: 3   DMEDDFMCDDEEDYDLEYSEDSNSEPNVDLENQYYNSKALKE 44
           D+ D F+ D+EEDY+    EDS+ EP  + E +    + LKE
Sbjct: 463 DLNDSFLDDEEEDYE-PTDEDSDWEPGKEDEEKEDVEELLKE 503


>gi|189217904 RPGRIP1-like isoform b [Homo sapiens]
          Length = 1235

 Score = 31.6 bits (70), Expect = 1.5
 Identities = 28/123 (22%), Positives = 53/123 (43%), Gaps = 12/123 (9%)

Query: 321 NDITEFEKILKTNHSNIMDDPFIREHIEELLRNIRTQVLIKLIKPYTRIHIPFISKELNI 380
           ND+ +  ++LK N+  + D  F   H E+           KL +   ++ I  +   L  
Sbjct: 349 NDLEKERELLKENYDKLYDSAFSAAHEEQW----------KLKEQQLKVQIAQLETALKS 398

Query: 381 DVADVESLLVQCILDNTIHGRIDQVNQLLELDH--QKRGGARYTALDKWTNQLNSLNQAV 438
           D+ D   +L +   +   + ++ Q N+ L+L +  QK+         K  NQ N +N   
Sbjct: 399 DLTDKTEILDRLKTERDQNEKLVQENRELQLQYLEQKQQLDELKKRIKLYNQENDINADE 458

Query: 439 VSK 441
           +S+
Sbjct: 459 LSE 461


>gi|118442834 RPGRIP1-like isoform a [Homo sapiens]
          Length = 1315

 Score = 31.6 bits (70), Expect = 1.5
 Identities = 28/123 (22%), Positives = 53/123 (43%), Gaps = 12/123 (9%)

Query: 321 NDITEFEKILKTNHSNIMDDPFIREHIEELLRNIRTQVLIKLIKPYTRIHIPFISKELNI 380
           ND+ +  ++LK N+  + D  F   H E+           KL +   ++ I  +   L  
Sbjct: 349 NDLEKERELLKENYDKLYDSAFSAAHEEQW----------KLKEQQLKVQIAQLETALKS 398

Query: 381 DVADVESLLVQCILDNTIHGRIDQVNQLLELDH--QKRGGARYTALDKWTNQLNSLNQAV 438
           D+ D   +L +   +   + ++ Q N+ L+L +  QK+         K  NQ N +N   
Sbjct: 399 DLTDKTEILDRLKTERDQNEKLVQENRELQLQYLEQKQQLDELKKRIKLYNQENDINADE 458

Query: 439 VSK 441
           +S+
Sbjct: 459 LSE 461


>gi|46049110 myosin binding protein C, slow type isoform 4 [Homo
           sapiens]
          Length = 1123

 Score = 31.6 bits (70), Expect = 1.5
 Identities = 42/187 (22%), Positives = 76/187 (40%), Gaps = 29/187 (15%)

Query: 12  DEEDYDLEYSEDSNSEPNVDLENQYYNSKALKEDDPKAALSSFQKVLELEGEKGE----- 66
           D   +DLE  E + + PN+D+ + +  S   +ED  +   S   K  E++ ++ E     
Sbjct: 151 DSCSFDLEVHESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDV 210

Query: 67  WGFKALK-------QMIKINFKLTNFPEMMNRYKQLLTYIRSAVTRNYSEKSINSILDYI 119
           W  + LK       + I   + +T+   M+ R K++             EK   +    +
Sbjct: 211 W--ELLKNAKPSEYEKIAFQYGITDLRGMLKRLKRM----------RREEKKSAAFAKIL 258

Query: 120 STSKQMDLLQEFYETTLEALKDAKNDRLWFKTNTKLGKLYLEREEYGKLQKILRQLHQSC 179
             + Q+D  +      +  L D K +  W+K   ++        E+   Q+IL     +C
Sbjct: 259 DPAYQVD--KGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRIL--FINNC 314

Query: 180 Q-TDDGE 185
           Q TDD E
Sbjct: 315 QMTDDSE 321


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.133    0.376 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,307,692
Number of Sequences: 37866
Number of extensions: 650388
Number of successful extensions: 2461
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 45
Number of HSP's that attempted gapping in prelim test: 2413
Number of HSP's gapped (non-prelim): 91
length of query: 443
length of database: 18,247,518
effective HSP length: 105
effective length of query: 338
effective length of database: 14,271,588
effective search space: 4823796744
effective search space used: 4823796744
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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