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Search of human proteins with 4759182
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4759182 syntaxin 1A (brain) [Homo sapiens]
(288 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4759182 syntaxin 1A (brain) [Homo sapiens] 553 e-158
gi|16418379 syntaxin 1B [Homo sapiens] 472 e-133
gi|37577287 syntaxin 2 isoform 1 [Homo sapiens] 366 e-101
gi|37577162 syntaxin 2 isoform 2 [Homo sapiens] 362 e-100
gi|4759184 syntaxin 3 [Homo sapiens] 346 2e-95
gi|20149560 syntaxin 4 [Homo sapiens] 236 2e-62
gi|33667038 syntaxin 11 [Homo sapiens] 154 7e-38
gi|49258196 syntaxin 19 [Homo sapiens] 149 3e-36
gi|170932494 syntaxin 7 [Homo sapiens] 90 3e-18
gi|28933465 syntaxin 12 [Homo sapiens] 87 2e-17
gi|47778943 syntaxin 16 isoform a [Homo sapiens] 85 6e-17
gi|198041692 syntaxin 16 isoform d [Homo sapiens] 85 6e-17
gi|198041688 syntaxin 16 isoform c [Homo sapiens] 85 6e-17
gi|34447229 syntaxin 16 isoform b [Homo sapiens] 85 6e-17
gi|223972648 t-SNARE domain containing 1 [Homo sapiens] 53 4e-07
gi|34577114 cytomatrix protein p110 [Homo sapiens] 50 2e-06
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 48 9e-06
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 46 4e-05
gi|214010216 SMC6 protein [Homo sapiens] 45 7e-05
gi|13375848 SMC6 protein [Homo sapiens] 45 7e-05
gi|45446749 kinesin family member 5A [Homo sapiens] 44 1e-04
gi|45505178 cancer antigen 1 [Homo sapiens] 44 2e-04
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 43 4e-04
gi|5032131 syntaxin 6 [Homo sapiens] 43 4e-04
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 42 5e-04
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] 41 0.001
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 41 0.001
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 41 0.001
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 41 0.001
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 41 0.001
>gi|4759182 syntaxin 1A (brain) [Homo sapiens]
Length = 288
Score = 553 bits (1425), Expect = e-158
Identities = 288/288 (100%), Positives = 288/288 (100%)
Query: 1 MKDRTQELRTAKDSDDDDDVAVTVDRDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSA 60
MKDRTQELRTAKDSDDDDDVAVTVDRDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSA
Sbjct: 1 MKDRTQELRTAKDSDDDDDVAVTVDRDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSA 60
Query: 61 ILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSADLRIRKTQH 120
ILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSADLRIRKTQH
Sbjct: 61 ILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSADLRIRKTQH 120
Query: 121 STLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFASG 180
STLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFASG
Sbjct: 121 STLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFASG 180
Query: 181 IIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHA 240
IIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHA
Sbjct: 181 IIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHA 240
Query: 241 VDYVERAVSDTKKAVKYQSKARRKKIMIIICCVILGIVIASTVGGIFA 288
VDYVERAVSDTKKAVKYQSKARRKKIMIIICCVILGIVIASTVGGIFA
Sbjct: 241 VDYVERAVSDTKKAVKYQSKARRKKIMIIICCVILGIVIASTVGGIFA 288
>gi|16418379 syntaxin 1B [Homo sapiens]
Length = 288
Score = 472 bits (1215), Expect = e-133
Identities = 240/285 (84%), Positives = 270/285 (94%), Gaps = 1/285 (0%)
Query: 1 MKDRTQELRTAKDSDDDDDVAVTVDRDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSA 60
MKDRTQELR+AKDSDD+++V V VDRD FMDEFFEQVEEIRG I+K++E+VE+VK++HSA
Sbjct: 1 MKDRTQELRSAKDSDDEEEV-VHVDRDHFMDEFFEQVEEIRGCIEKLSEDVEQVKKQHSA 59
Query: 61 ILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSADLRIRKTQH 120
ILA+PNPDEKTK+ELE+L +DIKKTANKVRSKLK+IEQSIEQEEGLNRSSADLRIRKTQH
Sbjct: 60 ILAAPNPDEKTKQELEDLTADIKKTANKVRSKLKAIEQSIEQEEGLNRSSADLRIRKTQH 119
Query: 121 STLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFASG 180
STLSRKFVEVM+EYNATQS YR+RCK RIQRQLEITGRTTT+EELEDMLESG AIF
Sbjct: 120 STLSRKFVEVMTEYNATQSKYRDRCKDRIQRQLEITGRTTTNEELEDMLESGKLAIFTDD 179
Query: 181 IIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHA 240
I MDS ++KQAL+EIETRH+EIIKLE SIRELHDMF+DMAMLVESQGEMIDRIEYNVEH+
Sbjct: 180 IKMDSQMTKQALNEIETRHNEIIKLETSIRELHDMFVDMAMLVESQGEMIDRIEYNVEHS 239
Query: 241 VDYVERAVSDTKKAVKYQSKARRKKIMIIICCVILGIVIASTVGG 285
VDYVERAVSDTKKAVKYQSKARRKKIMIIICCV+LG+V+AS++GG
Sbjct: 240 VDYVERAVSDTKKAVKYQSKARRKKIMIIICCVVLGVVLASSIGG 284
>gi|37577287 syntaxin 2 isoform 1 [Homo sapiens]
Length = 287
Score = 366 bits (939), Expect = e-101
Identities = 189/287 (65%), Positives = 232/287 (80%), Gaps = 5/287 (1%)
Query: 1 MKDRTQELRTAKDSDDDDDVAVTVDRDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSA 60
M+DR +L TA +DD D V V++D FMD+FF QVEEIR IDKI + VEEVK+ HS
Sbjct: 1 MRDRLPDL-TACRKNDDGDTVVVVEKDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNHSI 59
Query: 61 ILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSADLRIRKTQH 120
IL++PNP+ K KEELE+L +IKKTANK+R+KLK+IEQS +Q+E NR+S DLRIR+TQH
Sbjct: 60 ILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRTSVDLRIRRTQH 119
Query: 121 STLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFASG 180
S LSRKFVE M+EYN Q+ +RER KGRIQRQLEITGRTTT +ELE+MLESG P+IF S
Sbjct: 120 SVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSD 179
Query: 181 IIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHA 240
II DS I++QAL+EIE+RH +I+KLE SIRELH+MFMDMAM VE+QGEMI+ IE NV +A
Sbjct: 180 IISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVMNA 239
Query: 241 VDYVERAVSDTKKAVKYQSKARRKKIMIIIC----CVILGIVIASTV 283
DYVE A +TKKA+KYQSKARRK + IIIC VILGI++A+T+
Sbjct: 240 TDYVEHAKEETKKAIKYQSKARRKLMFIIICVIVLLVILGIILATTL 286
>gi|37577162 syntaxin 2 isoform 2 [Homo sapiens]
Length = 288
Score = 362 bits (929), Expect = e-100
Identities = 186/284 (65%), Positives = 228/284 (80%), Gaps = 1/284 (0%)
Query: 1 MKDRTQELRTAKDSDDDDDVAVTVDRDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSA 60
M+DR +L TA +DD D V V++D FMD+FF QVEEIR IDKI + VEEVK+ HS
Sbjct: 1 MRDRLPDL-TACRKNDDGDTVVVVEKDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNHSI 59
Query: 61 ILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSADLRIRKTQH 120
IL++PNP+ K KEELE+L +IKKTANK+R+KLK+IEQS +Q+E NR+S DLRIR+TQH
Sbjct: 60 ILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRTSVDLRIRRTQH 119
Query: 121 STLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFASG 180
S LSRKFVE M+EYN Q+ +RER KGRIQRQLEITGRTTT +ELE+MLESG P+IF S
Sbjct: 120 SVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSD 179
Query: 181 IIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHA 240
II DS I++QAL+EIE+RH +I+KLE SIRELH+MFMDMAM VE+QGEMI+ IE NV +A
Sbjct: 180 IISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVMNA 239
Query: 241 VDYVERAVSDTKKAVKYQSKARRKKIMIIICCVILGIVIASTVG 284
DYVE A +TKKA+KYQSKARRKK +II V+L +IA +G
Sbjct: 240 TDYVEHAKEETKKAIKYQSKARRKKWIIIAVSVVLVAIIALIIG 283
>gi|4759184 syntaxin 3 [Homo sapiens]
Length = 289
Score = 346 bits (887), Expect = 2e-95
Identities = 181/286 (63%), Positives = 231/286 (80%), Gaps = 5/286 (1%)
Query: 1 MKDRTQELRTAK--DSDDDDDVAVTVDRDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKH 58
MKDR ++L+ + DD D V + +D FMDEFF ++EE R IDKI+E+VEE K+ +
Sbjct: 1 MKDRLEQLKAKQLTQDDDTDAVEIAIDNTAFMDEFFSEIEETRLNIDKISEHVEEAKKLY 60
Query: 59 SAILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSADLRIRKT 118
S IL++P P+ KTK++LE+L ++IKK AN VR+KLKS+E+ IE++E RSSADLRIRK+
Sbjct: 61 SIILSAPIPEPKTKDDLEQLTTEIKKRANNVRNKLKSMEKHIEEDEV--RSSADLRIRKS 118
Query: 119 QHSTLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFA 178
QHS LSRKFVEVM++YN Q D+RER KGRIQRQLEITG+ TT EELE+MLESGNPAIF
Sbjct: 119 QHSVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEITGKKTTDEELEEMLESGNPAIFT 178
Query: 179 SGIIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVE 238
SGII DS ISKQALSEIE RH +I++LE+SI+ELHDMFMD+AMLVE+QGEM+D IE NV
Sbjct: 179 SGII-DSQISKQALSEIEGRHKDIVRLESSIKELHDMFMDIAMLVENQGEMLDNIELNVM 237
Query: 239 HAVDYVERAVSDTKKAVKYQSKARRKKIMIIICCVILGIVIASTVG 284
H VD+VE+A +TKKAVKYQS+AR+K I+II+ V+L ++A +G
Sbjct: 238 HTVDHVEKARDETKKAVKYQSQARKKLIIIIVLVVVLLGILALIIG 283
>gi|20149560 syntaxin 4 [Homo sapiens]
Length = 297
Score = 236 bits (602), Expect = 2e-62
Identities = 135/298 (45%), Positives = 195/298 (65%), Gaps = 14/298 (4%)
Query: 1 MKDRTQELRTAKDSDDDDD---VAVTVDRDRFM-----DEFFEQVEEIRGFIDKIAENVE 52
M+DRT ELR DS D++D VA+ V +EFF +V IR I K+ V+
Sbjct: 1 MRDRTHELRQGDDSSDEEDKERVALVVHPGTARLGSPDEEFFHKVRTIRQTIVKLGNKVQ 60
Query: 53 EVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSAD 112
E++++ ILA+P P+E K+EL+ L +IK+ ++R +LK+IE E+ + N +S +
Sbjct: 61 ELEKQQVTILATPLPEESMKQELQNLRDEIKQLGREIRLQLKAIEPQKEEADE-NYNSVN 119
Query: 113 LRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTS-EELEDMLES 171
R+RKTQH LS++FVE++++ N+ QS+YRE+ RI+RQL+IT S EELE ML+S
Sbjct: 120 TRMRKTQHGVLSQQFVELINKCNSMQSEYREKNVERIRRQLKITNAGMVSDEELEQMLDS 179
Query: 172 GNPAIFASGIIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMID 231
G +F S I+ D+ +++QAL+EI RHSEI +LE SIRELHD+F +A VE QGEMI+
Sbjct: 180 GQSEVFVSNILKDTQVTRQALNEISARHSEIQQLERSIRELHDIFTFLATEVEMQGEMIN 239
Query: 232 RIEYNVEHAVDYVERAVSDTKKAVKYQSKARRKKIMIIIC----CVILGIVIASTVGG 285
RIE N+ + DYVER K A++ Q KAR+KK++I IC V+L ++I TV G
Sbjct: 240 RIEKNILSSADYVERGQEHVKTALENQKKARKKKVLIAICVSITVVLLAVIIGVTVVG 297
>gi|33667038 syntaxin 11 [Homo sapiens]
Length = 287
Score = 154 bits (390), Expect = 7e-38
Identities = 87/287 (30%), Positives = 155/287 (54%), Gaps = 13/287 (4%)
Query: 1 MKDRTQEL--------RTAKDSDDDDDVA---VTVDRDRFMDEFFEQVEEIRGFIDKIAE 49
MKDR EL + D DD+ D + + D ++ + + +I+ +
Sbjct: 1 MKDRLAELLDLSKQYDQQFPDGDDEFDSPHEDIVFETDHILESLYRDIRDIQDENQLLVA 60
Query: 50 NVEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRS 109
+V+ + ++++ L S K + + IK + KL+++++ E E +
Sbjct: 61 DVKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAAEAQHGP 120
Query: 110 -SADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDM 168
SA RI + Q++ L+ F M +YN + R+ CK RIQRQLEI G+ + +++EDM
Sbjct: 121 HSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIMGKEVSGDQIEDM 180
Query: 169 LESGNPAIFASGIIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGE 228
E G +F+ ++ D ++ AL+EIE+RH E+++LE+ IR++H++F+ MA+LVE Q +
Sbjct: 181 FEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELFLQMAVLVEKQAD 240
Query: 229 MIDRIEYNVEHAVDYVERAVSDTKKAVKYQSKARRKKIMIIICCVIL 275
++ IE NV+ VDY +A + +KAV+Y+ K + + CC L
Sbjct: 241 TLNVIELNVQKTVDYTGQAKAQVRKAVQYEEK-NPCRTLCCFCCPCL 286
>gi|49258196 syntaxin 19 [Homo sapiens]
Length = 294
Score = 149 bits (376), Expect = 3e-36
Identities = 88/283 (31%), Positives = 156/283 (55%), Gaps = 13/283 (4%)
Query: 1 MKDRTQELRTAKDSD------DDDDV----AVTVDRDRFMDEFFEQVEEIRGFIDKIAEN 50
+K RT+E+ ++DS ++ V AV +R+ + ++++++ I+ +A+N
Sbjct: 8 LKQRTKEIELSRDSHVSTTETEEQGVFLQQAVIYEREPVAERHLHEIQKLQESINNLADN 67
Query: 51 VEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNR-S 109
V++ ++ +++AS K E + +IK A + L + + +++ E N S
Sbjct: 68 VQKFGQQQKSLVASMRRFSLLKRE-STITKEIKIQAEYINRSLNDLVKEVKKSEVENGPS 126
Query: 110 SADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDML 169
S RI K+QH+ + R F ++M YN T + +E+CK I RQLE+ G+ + E++ DML
Sbjct: 127 SVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFILRQLEVAGKEMSEEDVNDML 186
Query: 170 ESGNPAIFASGIIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEM 229
G +F ++ + +I+K LSEIE RH E++ LEN I++L D+F+ +++LVE QGE
Sbjct: 187 HQGKWEVFNESLLTEINITKAQLSEIEQRHKELVNLENQIKDLRDLFIQISLLVEEQGES 246
Query: 230 IDRIEYNVEHAVDYVERAVSDTKKAVKYQSKARRKKIMIIICC 272
I+ IE V +YV AVKY+ K +++ CC
Sbjct: 247 INNIEMTVNSTKEYVNNTKEKFGLAVKYK-KRNPCRVLCCWCC 288
>gi|170932494 syntaxin 7 [Homo sapiens]
Length = 261
Score = 89.7 bits (221), Expect = 3e-18
Identities = 62/241 (25%), Positives = 116/241 (48%), Gaps = 5/241 (2%)
Query: 46 KIAENVEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEG 105
+I+ N++++ + I + N T ++ EL +++ K ++ I++
Sbjct: 17 RISSNIQKITQCSVEIQRTLN-QLGTPQDSPELRQQLQQKQQYTNQLAKETDKYIKEFGS 75
Query: 106 LNRSSADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCK---GRIQRQLEITGRTTTS 162
L + ++ R RK Q L +F ++ + Q ER K R++ ++G
Sbjct: 76 LPTTPSEQRQRKIQKDRLVAEFTTSLTNFQKVQRQAAEREKEFVARVRASSRVSGSFPED 135
Query: 163 EELEDMLESGNPAIFASGIIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAML 222
E L S + D I++ L I R S I +LE I +++++F D+ M+
Sbjct: 136 SSKERNLVSWESQTQPQVQVQDEEITEDDLRLIHERESSIRQLEADIMDINEIFKDLGMM 195
Query: 223 VESQGEMIDRIEYNVEHAVDYVERAVSDTKKAVKYQSKARRKKIMIIICCVILGIVIAST 282
+ QG++ID IE NVE+A +V++A +A YQ K+ RK + III +++G+ I S
Sbjct: 196 IHEQGDVIDSIEANVENAEVHVQQANQQLSRAADYQRKS-RKTLCIIILILVIGVAIISL 254
Query: 283 V 283
+
Sbjct: 255 I 255
>gi|28933465 syntaxin 12 [Homo sapiens]
Length = 276
Score = 86.7 bits (213), Expect = 2e-17
Identities = 65/255 (25%), Positives = 124/255 (48%), Gaps = 13/255 (5%)
Query: 32 EFFEQVEEIRGFIDKIAENVEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKVRS 91
+F ++ G I +I++ ++K S L + K +E L++L + A +
Sbjct: 21 DFSSIIQTCSGNIQRISQATAQIKNLMSQ-LGTKQDSSKLQENLQQLQHSTNQLAKETNE 79
Query: 92 KLKSIEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCKGRIQR 151
LK + L S+++ R ++ Q L F ++ + A Q E+ K I R
Sbjct: 80 LLKELGSL-----PLPLSTSEQRQQRLQKERLMNDFSAALNNFQAVQRRVSEKEKESIAR 134
Query: 152 QLEITGRTTTSEELEDMLESGNPAIFASGIIMDS---SISKQALSEIETRHSEIIKLENS 208
+ + + E+ L S + + + +I++Q L I+ R + I +LE
Sbjct: 135 ARAGSRLSAEERQREEQLVSFDSHEEWNQMQSQEDEVAITEQDLELIKERETAIRQLEAD 194
Query: 209 IRELHDMFMDMAMLVESQGEMIDRIEYNVEHAVDYVERAVSDTKKAVKYQSKARRKKIMI 268
I +++ +F D+AM++ QG++ID IE NVE + +VERA ++A YQ K+R+K ++
Sbjct: 195 ILDVNQIFKDLAMMIHDQGDLIDSIEANVESSEVHVERATEQLQRAAYYQKKSRKKMCIL 254
Query: 269 I----ICCVILGIVI 279
+ + +ILG++I
Sbjct: 255 VLVLSVIILILGLII 269
>gi|47778943 syntaxin 16 isoform a [Homo sapiens]
Length = 325
Score = 85.1 bits (209), Expect = 6e-17
Identities = 69/274 (25%), Positives = 138/274 (50%), Gaps = 21/274 (7%)
Query: 17 DDDVAVTVDRDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSAILASPNPDEKTKEE-- 74
D + A+ V + R ++ + V+EI+ + +I + ++E+ H L P D+ ++EE
Sbjct: 63 DPEAAIGVTK-RPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHA 121
Query: 75 LEELMSDIKKTANKVRSKLKSIE---QSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVM 131
+E +I + ++ + ++++ ++ ++EG R+ ++L++ E+
Sbjct: 122 IEITTQEITQLFHRCQRAVQALPSRARACSEQEG--------RLLGNVVASLAQALQELS 173
Query: 132 SEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFASGIIMDSSIS-KQ 190
+ + QS Y +R K R +R TS L D + + ++ G D + +Q
Sbjct: 174 TSFRHAQSGYLKRMKNREERSQHFFD---TSVPLMD--DGDDNTLYHRGFTEDQLVLVEQ 228
Query: 191 ALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHAVDYVERAVSD 250
+E R EI ++ SI +L+++F D+ ++ QG ++DRI+YNVE + E +
Sbjct: 229 NTLMVEEREREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQ 288
Query: 251 TKKAVKYQSKARRKKIMIIICCVILGIVIASTVG 284
KA +YQ K RK ++I+I VI+ ++I VG
Sbjct: 289 LHKAEQYQKK-NRKMLVILILFVIIIVLIVVLVG 321
>gi|198041692 syntaxin 16 isoform d [Homo sapiens]
Length = 308
Score = 85.1 bits (209), Expect = 6e-17
Identities = 69/274 (25%), Positives = 138/274 (50%), Gaps = 21/274 (7%)
Query: 17 DDDVAVTVDRDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSAILASPNPDEKTKEE-- 74
D + A+ V + R ++ + V+EI+ + +I + ++E+ H L P D+ ++EE
Sbjct: 46 DPEAAIGVTK-RPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHA 104
Query: 75 LEELMSDIKKTANKVRSKLKSIE---QSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVM 131
+E +I + ++ + ++++ ++ ++EG R+ ++L++ E+
Sbjct: 105 IEITTQEITQLFHRCQRAVQALPSRARACSEQEG--------RLLGNVVASLAQALQELS 156
Query: 132 SEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFASGIIMDSSIS-KQ 190
+ + QS Y +R K R +R TS L D + + ++ G D + +Q
Sbjct: 157 TSFRHAQSGYLKRMKNREERSQHFFD---TSVPLMD--DGDDNTLYHRGFTEDQLVLVEQ 211
Query: 191 ALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHAVDYVERAVSD 250
+E R EI ++ SI +L+++F D+ ++ QG ++DRI+YNVE + E +
Sbjct: 212 NTLMVEEREREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQ 271
Query: 251 TKKAVKYQSKARRKKIMIIICCVILGIVIASTVG 284
KA +YQ K RK ++I+I VI+ ++I VG
Sbjct: 272 LHKAEQYQKK-NRKMLVILILFVIIIVLIVVLVG 304
>gi|198041688 syntaxin 16 isoform c [Homo sapiens]
Length = 321
Score = 85.1 bits (209), Expect = 6e-17
Identities = 69/274 (25%), Positives = 138/274 (50%), Gaps = 21/274 (7%)
Query: 17 DDDVAVTVDRDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSAILASPNPDEKTKEE-- 74
D + A+ V + R ++ + V+EI+ + +I + ++E+ H L P D+ ++EE
Sbjct: 59 DPEAAIGVTK-RPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHA 117
Query: 75 LEELMSDIKKTANKVRSKLKSIE---QSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVM 131
+E +I + ++ + ++++ ++ ++EG R+ ++L++ E+
Sbjct: 118 IEITTQEITQLFHRCQRAVQALPSRARACSEQEG--------RLLGNVVASLAQALQELS 169
Query: 132 SEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFASGIIMDSSIS-KQ 190
+ + QS Y +R K R +R TS L D + + ++ G D + +Q
Sbjct: 170 TSFRHAQSGYLKRMKNREERSQHFFD---TSVPLMD--DGDDNTLYHRGFTEDQLVLVEQ 224
Query: 191 ALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHAVDYVERAVSD 250
+E R EI ++ SI +L+++F D+ ++ QG ++DRI+YNVE + E +
Sbjct: 225 NTLMVEEREREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQ 284
Query: 251 TKKAVKYQSKARRKKIMIIICCVILGIVIASTVG 284
KA +YQ K RK ++I+I VI+ ++I VG
Sbjct: 285 LHKAEQYQKK-NRKMLVILILFVIIIVLIVVLVG 317
>gi|34447229 syntaxin 16 isoform b [Homo sapiens]
Length = 304
Score = 85.1 bits (209), Expect = 6e-17
Identities = 69/274 (25%), Positives = 138/274 (50%), Gaps = 21/274 (7%)
Query: 17 DDDVAVTVDRDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSAILASPNPDEKTKEE-- 74
D + A+ V + R ++ + V+EI+ + +I + ++E+ H L P D+ ++EE
Sbjct: 42 DPEAAIGVTK-RPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHA 100
Query: 75 LEELMSDIKKTANKVRSKLKSIE---QSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVM 131
+E +I + ++ + ++++ ++ ++EG R+ ++L++ E+
Sbjct: 101 IEITTQEITQLFHRCQRAVQALPSRARACSEQEG--------RLLGNVVASLAQALQELS 152
Query: 132 SEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFASGIIMDSSIS-KQ 190
+ + QS Y +R K R +R TS L D + + ++ G D + +Q
Sbjct: 153 TSFRHAQSGYLKRMKNREERSQHFFD---TSVPLMD--DGDDNTLYHRGFTEDQLVLVEQ 207
Query: 191 ALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHAVDYVERAVSD 250
+E R EI ++ SI +L+++F D+ ++ QG ++DRI+YNVE + E +
Sbjct: 208 NTLMVEEREREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQ 267
Query: 251 TKKAVKYQSKARRKKIMIIICCVILGIVIASTVG 284
KA +YQ K RK ++I+I VI+ ++I VG
Sbjct: 268 LHKAEQYQKK-NRKMLVILILFVIIIVLIVVLVG 300
>gi|223972648 t-SNARE domain containing 1 [Homo sapiens]
Length = 513
Score = 52.8 bits (125), Expect = 4e-07
Identities = 54/263 (20%), Positives = 122/263 (46%), Gaps = 24/263 (9%)
Query: 35 EQVEEIRGFIDKIAENVEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKVRSKLK 94
E +E+ + +I +V ++R + L +P+ ++ ++ L + KT S +K
Sbjct: 259 ELFQEMSANVFRINSSVTSLERSLQS-LGTPSDTQELRDSLHTAQQETNKTIAASASSVK 317
Query: 95 SIEQSIEQ---EEGLNRSSADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCKGRI-- 149
+ + + +E L + L KTQ S + + Y Q E+ + +
Sbjct: 318 QMAELLRSSCPQERLQQERPQLDRLKTQLS-------DAIQCYGVVQKKIAEKSRALLPM 370
Query: 150 -QRQLEITGRTTTSEELED-MLESGNPAIFAS---GIIMDSSISKQALSEIETRHSEIIK 204
QR + + + +E +D + +G+ ++ ++ D I+++ L I R I++
Sbjct: 371 AQRGSKQSPQAPFAELADDEKVFNGSDNMWQGQEQALLPD--ITEEDLEAIRLREEAILQ 428
Query: 205 LENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHAVDYVERAVSDTKKAVKYQSKARRK 264
+E+++ +++ + D+A +V QGE +D IE ++E A + E A A ++Q + +
Sbjct: 429 MESNLLDVNQIIKDLASMVSEQGEAVDSIEASLEAASSHAEAARQLLAGASRHQLQRHKI 488
Query: 265 KIMI----IICCVILGIVIASTV 283
K + +++ I+IA++V
Sbjct: 489 KCCFLSAGVTALLVIIIIIATSV 511
>gi|34577114 cytomatrix protein p110 [Homo sapiens]
Length = 957
Score = 50.4 bits (119), Expect = 2e-06
Identities = 45/171 (26%), Positives = 85/171 (49%), Gaps = 19/171 (11%)
Query: 1 MKDRTQELRTAKDSDDDDDVAVTVD-----RDRFMDEFFEQVE----EIRGFIDKIAENV 51
+KDR + L+T DS + D T++ ++R ++ EQ E E I+ +
Sbjct: 565 LKDRVKSLQT--DSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKEN 622
Query: 52 EEVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSA 111
+++K K +A+ A E + +L+E S + K SKLKS+E +IEQ++ S
Sbjct: 623 KDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKE-ECSKL 681
Query: 112 DLRIRKTQH----STLSRKFVEVMSEYNATQSDYRERC---KGRIQRQLEI 155
+ +++K + S ++ +F + + + + S YR+ C + + R LEI
Sbjct: 682 EAQLKKAHNIEDDSRMNPEFADQIKQLDKEASYYRDECGKAQAEVDRLLEI 732
Score = 45.8 bits (107), Expect = 4e-05
Identities = 44/249 (17%), Positives = 109/249 (43%), Gaps = 17/249 (6%)
Query: 25 DRDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSAILASPNPDEKTKEELEELMSDIKK 84
+++ F+++ +Q++++ +A + ++K N +K E L+E + D K
Sbjct: 501 EKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDK 560
Query: 85 TANKVRSKLKSIEQSIEQ--------EEGLNRSSADLRIRKTQHSTLSRKFVEVMSEYNA 136
++ ++KS++ EE L+ + K Q R+ +E + +
Sbjct: 561 QLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRK 620
Query: 137 TQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFASGIIMDSSISKQALSEIE 196
D +E+ Q E+T + ++ +L++ S + ++G+ DS + ++ IE
Sbjct: 621 ENKDLKEKVNA---LQAELTEKESSLIDLKEHASS----LASAGLKRDSKLKSLEIA-IE 672
Query: 197 TRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHAVDYVERAVSDTKKAVK 256
+ E KLE +++ H++ D M E + I +++ + D +A ++ + ++
Sbjct: 673 QKKEECSKLEAQLKKAHNIEDDSRMNPEF-ADQIKQLDKEASYYRDECGKAQAEVDRLLE 731
Query: 257 YQSKARRKK 265
+ +K
Sbjct: 732 ILKEVENEK 740
Score = 32.0 bits (71), Expect = 0.65
Identities = 22/75 (29%), Positives = 44/75 (58%), Gaps = 11/75 (14%)
Query: 46 KIAENVEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKV---RSKLKSIEQSIEQ 102
K A+ +EEV+R+ ++ D ++EELM+ ++KT ++ +++L S +QS+ +
Sbjct: 778 KNAQLLEEVRRREDSMA-----DNSQHLQIEELMNALEKTRQELDATKARLASTQQSLAE 832
Query: 103 EEGLNRSSADLRIRK 117
+E A+LRI +
Sbjct: 833 KEA---HLANLRIER 844
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 48.1 bits (113), Expect = 9e-06
Identities = 45/219 (20%), Positives = 107/219 (48%), Gaps = 11/219 (5%)
Query: 17 DDDVAVTVDRDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSAILASPNPDEKTKEELE 76
++++A R + M E++ E + ++ A EE+++ S + K K E++
Sbjct: 381 EEEIAQLRSRIKQMTTQGEELREQKEKSERAA--FEELEKALSTAQKTEEARRKLKAEMD 438
Query: 77 ELMSDIKKTANKVRSKLKSIEQSIEQE--EGLNRSSAD--LRIRKTQHSTLSRKFVEVMS 132
E + I+KT+ + R L+ ++QE + + +SS + +++K L+RK E+
Sbjct: 439 EQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTK 498
Query: 133 EYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFASGIIMDSSISKQAL 192
+ + +++E+ K +++ + + +E ++ L + I+ +S + L
Sbjct: 499 KLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDL 558
Query: 193 -SEIETRHSEIIKLEN----SIRELHDMFMDMAMLVESQ 226
E ET + I++LE+ S++E + D+A+ +E++
Sbjct: 559 QQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAE 597
Score = 36.2 bits (82), Expect = 0.034
Identities = 41/191 (21%), Positives = 81/191 (42%), Gaps = 37/191 (19%)
Query: 39 EIRGFIDKIAENVEEVKRKHSAILASPNPDE------KTKEELEELMSDIKKTANKVRSK 92
E + I + E +EE +K+S I+A E + K+ LE + D++KT +
Sbjct: 1789 EDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELT 1848
Query: 93 LKSIEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCKGRIQRQ 152
+ +EQ I++ + L +K H + E+ S+Y ++Q
Sbjct: 1849 CQILEQKIKELDSC------LVRQKEVHRV---EMEELTSKYE------------KLQAL 1887
Query: 153 LEITGRTTTSEELEDMLESGNPAIFASGIIMDSSISKQALSEIETRHSEI-IKLENSIRE 211
++ GR +E LE+ E + + + + LS +E +H+++ KL + RE
Sbjct: 1888 QQMDGRNKPTELLEENTEEKSKS---------HLVQPKLLSNMEAQHNDLEFKLAGAERE 1938
Query: 212 LHDMFMDMAML 222
+ ++ L
Sbjct: 1939 KQKLGKEIVRL 1949
Score = 35.8 bits (81), Expect = 0.045
Identities = 49/225 (21%), Positives = 93/225 (41%), Gaps = 12/225 (5%)
Query: 32 EFFEQVEEIRGFIDKIAENVEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKVRS 91
E E V++++ F + E VK IL N K ELE +++ V+S
Sbjct: 1558 EHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKS 1617
Query: 92 K---LKSIEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCKGR 148
K LK++E +E E A+L+ + Q +K +++S+ + Y++ +
Sbjct: 1618 KEEELKALEDRLESESA--AKLAELKRKAEQKIAAIKK--QLLSQMEEKEEQYKKGTESH 1673
Query: 149 I-QRQLEITGRTTTSEELEDMLESGNPAIFASGIIMDSSISKQALSEIETRHSEII---K 204
+ + ++ R LE+ L+S + + I+ S+ + A +E E S+
Sbjct: 1674 LSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKT 1733
Query: 205 LENSIRELHDMFMDMAMLVESQG-EMIDRIEYNVEHAVDYVERAV 248
E I L + L++ G E + + + E Y ER +
Sbjct: 1734 YEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLI 1778
Score = 30.0 bits (66), Expect = 2.5
Identities = 39/206 (18%), Positives = 91/206 (44%), Gaps = 32/206 (15%)
Query: 69 EKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQ--EEGLNRSSADLRIRKTQHSTLSRK 126
+K +E+ L D++ + + +L+ +++ +Q EE + + DL ++ +STL
Sbjct: 1940 QKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELK--HNSTLK-- 1995
Query: 127 FVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSEELE---DMLESGNPAIFASGIIM 183
++M E+N TQ +E ++LE+T + T ++ E ++LES
Sbjct: 1996 --QLMREFN-TQLAQKE-------QELEMTIKETINKAQEVEAELLES------------ 2033
Query: 184 DSSISKQALSEIETRHSEIIKLENSIRELHD-MFMDMAMLVESQGEMIDRIEYNVEHAVD 242
+ Q L +I + ++ + E+ D +M V ++ ++ + ++
Sbjct: 2034 HQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLE 2093
Query: 243 YVERAVSDTKKAVKYQSKARRKKIMI 268
E +D ++ Q++ +K +I
Sbjct: 2094 QEENPGNDNVTIMELQTQLAQKTTLI 2119
Score = 29.6 bits (65), Expect = 3.2
Identities = 48/247 (19%), Positives = 106/247 (42%), Gaps = 28/247 (11%)
Query: 35 EQVEEIRGFID----KIAENVEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKVR 90
EQ+ E++ + K++E ++K + + EK+ + LE+ + KK + ++
Sbjct: 1155 EQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELA 1214
Query: 91 SKL----KSIEQSIEQE--EGLNRSSADL-----RIRKTQHSTLSRKFVEVMSEYNATQS 139
+L K E +E + E +N SS+ RI QH T K ++ ++
Sbjct: 1215 IQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLIKTCTVSEL 1274
Query: 140 DYRERCKGRIQRQLEITGRTTTS--EELEDMLESGNPAIFA-----SGIIMDSSISKQAL 192
+ + R Q L I+ + T EE E+ ++S I + + + +QA
Sbjct: 1275 EAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAA 1334
Query: 193 SEIET----RHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHAVDYVER-- 246
SE E+ E+ + N++ + + + + + S + + + +++++ E+
Sbjct: 1335 SEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEA 1394
Query: 247 AVSDTKK 253
A+S +K
Sbjct: 1395 AISSLRK 1401
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 45.8 bits (107), Expect = 4e-05
Identities = 44/208 (21%), Positives = 95/208 (45%), Gaps = 23/208 (11%)
Query: 32 EFFEQVEEIRGFIDKIAENVEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKVRS 91
+F ++++E++ I+++ E E++ +H+ ELEE+ +++ + +
Sbjct: 1107 QFQKKIKELQARIEELEE---EIEAEHTLRAKIEKQRSDLARELEEISERLEEASGATSA 1163
Query: 92 KLKSIEQSIEQEEGLNRSSADLRIRKTQH----STLSRKFVEVMSEYNATQSDYRERCKG 147
+ IE + ++E + DL QH +TL +K + ++E Q D +R K
Sbjct: 1164 Q---IEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGE-QIDNLQRVKQ 1219
Query: 148 RIQRQLEITGRTTTSEELEDMLESGNPAIFASGIIMDSSISKQALSEIETRHSEI-IKLE 206
+++++ ++ E++DM + + S ++ +E + SEI K E
Sbjct: 1220 KLEKE-----KSELKMEIDDMASN------IEALSKSKSNIERTCRTVEDQFSEIKAKDE 1268
Query: 207 NSIRELHDMFMDMAMLVESQGEMIDRIE 234
+ +HD+ M A L GE+ R+E
Sbjct: 1269 QQTQLIHDLNMQKARLQTQNGELSHRVE 1296
Score = 44.7 bits (104), Expect = 1e-04
Identities = 43/200 (21%), Positives = 92/200 (46%), Gaps = 16/200 (8%)
Query: 69 EKTKEELEELMSDIKKTAN----KVRSKLKSIEQSIEQEEGLNRSSADLRIRKTQHSTLS 124
E ++ELEE M + + N +V+S+ +++ + E+ EGL +S L + + +
Sbjct: 871 EARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCEGLIKSKILLEAKVKELTERL 930
Query: 125 RKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFASGIIMD 184
+ E+ SE A + + ++C ++R ++ T T E E
Sbjct: 931 EEEEEMNSELVAKKRNLEDKCSS-LKRDIDDLELTLTKVEKEKHATENKV---------- 979
Query: 185 SSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHAVDYV 244
++S++ ++ +E S++ K + S++E H +D + E + + +I +E D +
Sbjct: 980 KNLSEE-MTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDL 1038
Query: 245 ERAVSDTKKAVKYQSKARRK 264
E ++ KK +A+RK
Sbjct: 1039 EGSLEQEKKLRADLERAKRK 1058
Score = 38.5 bits (88), Expect = 0.007
Identities = 48/250 (19%), Positives = 110/250 (44%), Gaps = 12/250 (4%)
Query: 26 RDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSAILASPNPDEKTKEEL----EELMSD 81
R ++ + ++ EE+ K+A+ ++E + + EKTK+ L E+LM D
Sbjct: 1376 RTKYETDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRD 1435
Query: 82 IKKT---ANKVRSKLKSIEQSI-EQEEGLNRSSADLRIRKTQHSTLSRKFVEVMSEYNAT 137
++++ + K ++ ++ + E ++ L+ S A+L + + +LS + ++ + Y
Sbjct: 1436 LERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEV 1495
Query: 138 QSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFASGIIMDSSISKQALSEIE- 196
+ Q EI+ T E L+ + + S + AL E+E
Sbjct: 1496 VDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKT--KKLVEQEKSDLQVALEEVEG 1553
Query: 197 TRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHAVDYVERAVSDTKKAVK 256
+ E K+ EL + ++ V + E I++++ N + A + ++ +V D + +
Sbjct: 1554 SLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQ-SVLDAEIRSR 1612
Query: 257 YQSKARRKKI 266
+ +KK+
Sbjct: 1613 NDALRLKKKM 1622
Score = 31.2 bits (69), Expect = 1.1
Identities = 45/224 (20%), Positives = 99/224 (44%), Gaps = 23/224 (10%)
Query: 31 DEFFEQVEEIRGFIDKIAENVEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKVR 90
+E +Q+E +R + E + ++ + + + EKTK+ +E+ SD++
Sbjct: 1493 EEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVA----- 1547
Query: 91 SKLKSIEQSIEQEEGLNRSSADLRIR---KTQHSTLSRKFVEVMSEYNATQSDYRERCKG 147
L+ +E S+E EE S LR++ S L RK +E E + + +R
Sbjct: 1548 --LEEVEGSLEHEE-----SKILRVQLELSQVKSELDRKVIEKDEEIEQLKRN-SQRAAE 1599
Query: 148 RIQRQLEITGRTTT-----SEELEDMLESGNPAIFASGIIMDSSISKQALSEIETRHSEI 202
+Q L+ R+ +++E L + S M + + + + S+
Sbjct: 1600 ALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQ- 1658
Query: 203 IKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHAVDYVER 246
+ L++++R D+ +A++ G +++ +E ++ A++ ER
Sbjct: 1659 LHLDDALRSNEDLKEQLAIVERRNGLLLEELE-EMKVALEQTER 1701
Score = 28.9 bits (63), Expect = 5.5
Identities = 39/203 (19%), Positives = 90/203 (44%), Gaps = 26/203 (12%)
Query: 70 KTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNR-SSADLRIRKTQHSTLSRKFV 128
++ E+L+E ++ +++ + +L+ ++ ++EQ E R S +L + L +
Sbjct: 1666 RSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNT 1725
Query: 129 EVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFASGIIMDSSIS 188
+++ ++D + C+ ++ ++ ES N A I D+++
Sbjct: 1726 SLINTKKKLEADIAQ-CQAEVENSIQ---------------ESRNAEEKAKKAITDAAMM 1769
Query: 189 KQALSEIE--TRHSEIIK--LENSIRELHDMFMDMAMLVESQG-EMIDRIEYNV---EHA 240
+ L + + + H E +K LE ++++L + L G + I ++E V E+
Sbjct: 1770 AEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLENRVRELENE 1829
Query: 241 VDYVE-RAVSDTKKAVKYQSKAR 262
+D + R K A KY+ K +
Sbjct: 1830 LDVEQKRGAEALKGAHKYERKVK 1852
>gi|214010216 SMC6 protein [Homo sapiens]
Length = 1091
Score = 45.1 bits (105), Expect = 7e-05
Identities = 45/210 (21%), Positives = 88/210 (41%), Gaps = 30/210 (14%)
Query: 51 VEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQ--EEGLNR 108
V E++++ +AI + E L+ M + + N+ K K I+ +E+ EE R
Sbjct: 283 VNEIEKQLNAIRDNIKIGEDRAARLDRKMEEQQVRLNEAEQKYKDIQDKLEKISEETNAR 342
Query: 109 S------SADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTS 162
+ AD+ +K ++ + ++EY A + D + CK RI+ + T ++
Sbjct: 343 APECMALKADVVAKKRAYNEAEVLYNRSLNEYKALKKDDEQLCK-RIEELKKSTDQSLEP 401
Query: 163 EELEDMLESGNPAIFASGIIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAML 222
E LE ++ +S ++ R ENS+ + + F
Sbjct: 402 ERLE---------------------RQKKISWLKERVKAFQNQENSVNQEIEQFQQAIEK 440
Query: 223 VESQGEMIDRIEYNVEHAVDYVERAVSDTK 252
+ + I R E +V+HA+ Y +R + + K
Sbjct: 441 DKEEHGKIKREELDVKHALSYNQRQLKELK 470
>gi|13375848 SMC6 protein [Homo sapiens]
Length = 1091
Score = 45.1 bits (105), Expect = 7e-05
Identities = 45/210 (21%), Positives = 88/210 (41%), Gaps = 30/210 (14%)
Query: 51 VEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQ--EEGLNR 108
V E++++ +AI + E L+ M + + N+ K K I+ +E+ EE R
Sbjct: 283 VNEIEKQLNAIRDNIKIGEDRAARLDRKMEEQQVRLNEAEQKYKDIQDKLEKISEETNAR 342
Query: 109 S------SADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTS 162
+ AD+ +K ++ + ++EY A + D + CK RI+ + T ++
Sbjct: 343 APECMALKADVVAKKRAYNEAEVLYNRSLNEYKALKKDDEQLCK-RIEELKKSTDQSLEP 401
Query: 163 EELEDMLESGNPAIFASGIIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAML 222
E LE ++ +S ++ R ENS+ + + F
Sbjct: 402 ERLE---------------------RQKKISWLKERVKAFQNQENSVNQEIEQFQQAIEK 440
Query: 223 VESQGEMIDRIEYNVEHAVDYVERAVSDTK 252
+ + I R E +V+HA+ Y +R + + K
Sbjct: 441 DKEEHGKIKREELDVKHALSYNQRQLKELK 470
>gi|45446749 kinesin family member 5A [Homo sapiens]
Length = 1032
Score = 44.3 bits (103), Expect = 1e-04
Identities = 52/255 (20%), Positives = 108/255 (42%), Gaps = 34/255 (13%)
Query: 13 DSDDDDDV--AVTVDRDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSAILASPNPDEK 70
D+ D D+V A+ + + + Q+ +R I++ + ++E+K + ++K
Sbjct: 688 DTQDADEVKKALELQMESHREAHHRQLARLRDEINEKQKTIDELK----------DLNQK 737
Query: 71 TKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEV 130
+ ELE+L +D +K ++ K +++ E +S DL K T++R+ +
Sbjct: 738 LQLELEKLQADYEKLKSEEHEKSTKLQELTFLYERHEQSKQDL---KGLEETVARELQTL 794
Query: 131 MSEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFASGIIMDSSISKQ 190
+ D R K + + E +G + ++ LE+ + + + KQ
Sbjct: 795 HNLRKLFVQDVTTRVKKSAEMEPEDSGGIHSQKQKISFLENNLEQL--------TKVHKQ 846
Query: 191 ALSEIETRHSEIIKLENSIRELHDMF--MDMAMLVESQGEMIDRIEYNVEHAVDYVERAV 248
+ + E+ KLE +R + ++ A+ +G M D+ Y E V
Sbjct: 847 LVRDNADLRCELPKLEKRLRATAERVKALEGALKEAKEGAMKDKRRYQQE---------V 897
Query: 249 SDTKKAVKYQSKARR 263
K+AV+Y+S +R
Sbjct: 898 DRIKEAVRYKSSGKR 912
Score = 36.2 bits (82), Expect = 0.034
Identities = 48/260 (18%), Positives = 119/260 (45%), Gaps = 40/260 (15%)
Query: 15 DDDDDVAVTV---DRDRFMDEF---FEQVEEIRGFIDKIAENVEEVKRK----HSAILAS 64
+D+ + V + +R ++ +E ++Q+++ I++ ++ +E++K++ ++++
Sbjct: 400 NDNSSIVVRIAPEERQKYEEEIRRLYKQLDDKDDEINQQSQLIEKLKQQMLDQEELLVST 459
Query: 65 PNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSADLRIRKTQHSTLS 124
+EK + EL L S+ ++V+ L+++E E ++ S ++ + Q+ L
Sbjct: 460 RGDNEKVQRELSHLQSENDAAKDEVKEVLQALE---ELAVNYDQKSQEVEEKSQQNQLL- 515
Query: 125 RKFVEVMSEYNATQSDYRERCKGRIQRQLEITG--RTTTSEELEDMLES--------GN- 173
V+ +S+ AT + +QR E++G R +E L +++ GN
Sbjct: 516 ---VDELSQKVATMLS----LESELQRLQEVSGHQRKRIAEVLNGLMKDLSEFSVIVGNG 568
Query: 174 ----PAIFASGIIMDSSISKQALSEIETRHSEIIK----LENSIRELHDMFMDMAMLVES 225
P + I + ++++ +S+I++ ++K LEN E H + S
Sbjct: 569 EIKLPVEISGAIEEEFTVARLYISKIKSEVKSVVKRCRQLENLQVECHRKMEVTGRELSS 628
Query: 226 QGEMIDRIEYNVEHAVDYVE 245
+I + E + +Y++
Sbjct: 629 CQLLISQHEAKIRSLTEYMQ 648
>gi|45505178 cancer antigen 1 [Homo sapiens]
Length = 641
Score = 43.5 bits (101), Expect = 2e-04
Identities = 40/182 (21%), Positives = 78/182 (42%), Gaps = 23/182 (12%)
Query: 44 IDKIAENVEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQE 103
I+K+ ENVEE+ I+ N +KT + LEE++++ +K + R+ + ++ ++
Sbjct: 218 INKLKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRNDKEMLQLQFKK- 276
Query: 104 EGLNRSSADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSE 163
K + L +++ M + N + S Y E K +++ E+ +
Sbjct: 277 ------------IKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKK 324
Query: 164 ELE-------DMLESGNPAIFASGIIMD---SSISKQALSEIETRHSEIIKLENSIRELH 213
ELE D+L+ A + + + K+ L E + S + KL +R L
Sbjct: 325 ELEKATASALDLLKREKEAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQVRNLQ 384
Query: 214 DM 215
M
Sbjct: 385 FM 386
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 42.7 bits (99), Expect = 4e-04
Identities = 56/257 (21%), Positives = 117/257 (45%), Gaps = 50/257 (19%)
Query: 35 EQVEEIRGFIDKIAENVEEVKRKHSAILASPNPDEKTKEELEELMSDI-------KKTAN 87
E EE++ K+ +++E + ++H +A+ + EKTK L++ + D+ +++A
Sbjct: 1381 ETAEEVKR---KLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSAC 1437
Query: 88 KVRSKLKSIEQSIEQE--------EGLNRSSADLRIRKTQHSTLSRKFVEVMSEYNATQS 139
+ K K +Q + +E E +R+ A+ R ++T+ +L+R E M +
Sbjct: 1438 NLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQ------ 1491
Query: 140 DYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFASGIIMDSSISKQAL-SEIETR 198
K ++R L RT E+ED++ S + + + SK+AL ++E
Sbjct: 1492 ------KAELER-LNKQFRT----EMEDLMSSKDD---VGKSVHELEKSKRALEQQVEEM 1537
Query: 199 HSEIIKLENSIRELHDMFMDM-----AMLVESQGEMIDRIEYNVE------HAVDYVERA 247
+++ +LE+ ++ D + + AM + + ++ R E + E V +E
Sbjct: 1538 KTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAE 1597
Query: 248 VSDTKKAVKYQSKARRK 264
+ D +K AR+K
Sbjct: 1598 LEDERKQRSMAVAARKK 1614
Score = 37.7 bits (86), Expect = 0.012
Identities = 32/146 (21%), Positives = 63/146 (43%), Gaps = 11/146 (7%)
Query: 28 RFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTAN 87
R ++E EQ E+ + +E++ + S + EK+K LE+ + ++K
Sbjct: 1483 RALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLE 1542
Query: 88 KVRSKLKSIEQS-IEQEEGLNRSSA----DLRIRKTQHSTLSRKFVEVMSEYNATQSDYR 142
++ +L++ E + + E L A DL+ R Q ++ V + E A D R
Sbjct: 1543 ELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDER 1602
Query: 143 ERCKGRIQRQLEITGRTTTSEELEDM 168
+ QR + + R +L+D+
Sbjct: 1603 K------QRSMAVAARKKLEMDLKDL 1622
Score = 33.5 bits (75), Expect = 0.22
Identities = 47/303 (15%), Positives = 123/303 (40%), Gaps = 46/303 (15%)
Query: 2 KDRTQELRTAKDSDDD-DDVAVTVDR-DRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHS 59
K R+ + K + D D+ +D ++ DE +Q+ +++ + +++ +
Sbjct: 1603 KQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASRE 1662
Query: 60 AILASPNPDEK-------------------------TKEELEELMSDIKKTANK------ 88
ILA +EK ++E +EL +I ++ K
Sbjct: 1663 EILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALE 1722
Query: 89 ----VRSKLKSIEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRER 144
+ +++ +E+ +E+E+G N + R++K + + ++ ++ N +S ++
Sbjct: 1723 EKRRLEARIAQLEEELEEEQG-NTELINDRLKKA-----NLQIDQINTDLNLERSHAQKN 1776
Query: 145 CKGRIQRQLEITGRTTTSEELEDMLESGNPAIFASGIIMDSSISKQALSEIETRHSEIIK 204
R Q + + +E+E ++S A + + + +Q +E + R + +
Sbjct: 1777 ENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQ 1836
Query: 205 LENSIRELHDMFM---DMAMLVESQGEMIDRIEYNVEHAVDYVERAVSDTKKAVKYQSKA 261
+ + ++L D+ + D E + D+ ++ +E A + ++A + K
Sbjct: 1837 VRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKL 1896
Query: 262 RRK 264
+R+
Sbjct: 1897 QRE 1899
Score = 32.7 bits (73), Expect = 0.38
Identities = 45/255 (17%), Positives = 104/255 (40%), Gaps = 27/255 (10%)
Query: 38 EEIRGFIDKIAENVEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKVR------- 90
+E+ + VEE + + + A ++ +ELEE + + + K++
Sbjct: 911 QELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTE 970
Query: 91 SKLKSIEQS-----------IEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMSEYNATQS 139
+KLK +E+ ++++ L A+ T+ S+ ++ +++ A +
Sbjct: 971 AKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMIT 1030
Query: 140 DYRERCK--GRIQRQLEITGRTT--TSEELEDMLE--SGNPAIFASGIIMDSSISKQALS 193
D ER + + +++LE T R S +L D + A + + AL+
Sbjct: 1031 DLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALA 1090
Query: 194 EIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIE---YNVEHAVDYVERAVSD 250
+E ++ IREL ++ +ES+ ++ E ++ ++ ++ + D
Sbjct: 1091 RVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELED 1150
Query: 251 TKKAVKYQSKARRKK 265
T + Q + R K+
Sbjct: 1151 TLDSTAAQQELRSKR 1165
Score = 28.5 bits (62), Expect = 7.2
Identities = 49/265 (18%), Positives = 105/265 (39%), Gaps = 29/265 (10%)
Query: 27 DRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTA 86
+R E ++V +++ +D + + + K S + + E ++ +EL+ + +
Sbjct: 1265 ERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQK 1324
Query: 87 NKVRSKLKSIE-------QSIEQEE----GLNRSSADLRIRKTQHSTLSRKFVEVMSEYN 135
+ +KLK +E + +E+EE L + A L + V +
Sbjct: 1325 LSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAE 1384
Query: 136 ATQSDYRERCKGRIQR---------QLEITGRTTTSEELEDML-ESGNPAIFASGIIMDS 185
+ ++ +G QR +LE T +T +EL+D+L + + A +
Sbjct: 1385 EVKRKLQKDLEGLSQRHEEKVAAYDKLEKT-KTRLQQELDDLLVDLDHQRQSACNLEKKQ 1443
Query: 186 SISKQALSEIETRHS----EIIKLENSIRELHDMFMDMAMLVESQGEM---IDRIEYNVE 238
Q L+E +T + E + E RE + +A +E E ++R+
Sbjct: 1444 KKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFR 1503
Query: 239 HAVDYVERAVSDTKKAVKYQSKARR 263
++ + + D K+V K++R
Sbjct: 1504 TEMEDLMSSKDDVGKSVHELEKSKR 1528
>gi|5032131 syntaxin 6 [Homo sapiens]
Length = 255
Score = 42.7 bits (99), Expect = 4e-04
Identities = 56/258 (21%), Positives = 105/258 (40%), Gaps = 36/258 (13%)
Query: 40 IRGFIDKIAENVEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQS 99
++G + K + + ++ + +L P+ T+EE++ T N++R+ L+SIE
Sbjct: 10 VKGEVQKAVNTAQGLFQRWTELLQDPST--ATREEIDW-------TTNELRNNLRSIEWD 60
Query: 100 IE-----------QEEGLNRSSADLRIRKTQHSTLSRKFVEVMSEYNATQS-------DY 141
+E N + +L IRK T +R+ V M + +T S
Sbjct: 61 LEDLDETISIVEANPRKFNLDATELSIRKA-FITSTRQVVRDMKDQMSTSSVQALAERKN 119
Query: 142 RERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFASGIIMDSSISKQALSEIETRHSE 201
R+ G Q TG T L+ L+ N S I + +Q + E + E
Sbjct: 120 RQALLGDSGSQNWSTGTTDKYGRLDRELQRAN-----SHFIEEQQAQQQLIVEQQDEQLE 174
Query: 202 IIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHAVDYVERAVSDTKKAVKYQSKA 261
++ SI L +M + +E Q M++ + +E ++ + K V + +
Sbjct: 175 LV--SGSIGVLKNMSQRIGGELEEQAVMLEDFSHELESTQSRLDNVMKKLAK-VSHMTSD 231
Query: 262 RRKKIMIIICCVILGIVI 279
RR+ I I +L +V+
Sbjct: 232 RRQWCAIAILFAVLLVVL 249
>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
Length = 3899
Score = 42.4 bits (98), Expect = 5e-04
Identities = 49/213 (23%), Positives = 99/213 (46%), Gaps = 27/213 (12%)
Query: 36 QVEEIRGFIDKIAENVEEVKRKHSAILASPNP-DEKTKEELEELMSD---IKKTANKVRS 91
+++E+ +I E E + R+ A+ A P +++ +E E+LM + ++ A KVR
Sbjct: 1958 RLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMKEKLEVQCQAEKVRD 2017
Query: 92 KLKS------------IEQSIEQEEGLNRSSADLRIRKT---QHSTLSRKFVEVMSEYNA 136
L+ + + IE E+ N DLR + + RKF++ +
Sbjct: 2018 DLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDRE 2077
Query: 137 TQSDYRERCKGRIQRQLEITGR--TTTSEELEDMLESGNPAIFASGIIMDSSISKQALS- 193
+ D ++ ++++QL++ R + + ++ + N + + +SK+ L
Sbjct: 2078 HERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQR 2137
Query: 194 EIETRHSEIIKLENSIRELHDMFMDMAMLVESQ 226
+I+ R+ EI KLE +REL + A+LVE +
Sbjct: 2138 DIQERNEEIEKLEFRVREL-----EQALLVEDR 2165
Score = 37.7 bits (86), Expect = 0.012
Identities = 37/177 (20%), Positives = 79/177 (44%), Gaps = 12/177 (6%)
Query: 45 DKIAENVEEVKRKHSAILASPNPDEKTKEELEELM---SDIKKTANKVRSKLKSIEQSIE 101
++I + +E+K + S + ++ EE+++LM +++K +K I Q +E
Sbjct: 364 EQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRME 423
Query: 102 QEEGLNRSSADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTT 161
QE + + + + E++ ++ A + + R KG ++ L T
Sbjct: 424 QETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENALRSYSNITV 483
Query: 162 SEELEDMLESGNPAIFASGI-IMDSSISKQALSE-----IETRHSEIIKLENSIREL 212
+ ED ++ N AI I + D++ K+ L E +E + + +LE+ + EL
Sbjct: 484 N---EDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEEL 537
Score = 36.6 bits (83), Expect = 0.026
Identities = 32/116 (27%), Positives = 55/116 (47%), Gaps = 4/116 (3%)
Query: 50 NVEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRS 109
N+E++ H + L+S EKTK LEE + +++ + ++ +LK EQ+ E E +
Sbjct: 1313 NLEDIDVNHKSKLSSLQDLEKTK--LEEQVQELESLISSLQQQLKETEQNYEAEIHCLQK 1370
Query: 110 SADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRERC-KGRIQRQLEITGRTTTSEE 164
T +L V V++E +A ++ Y C K I +E +G EE
Sbjct: 1371 RLQAVSESTVPPSLPVDSV-VITESDAQRTMYPGSCVKKNIDGTIEFSGEFGVKEE 1425
Score = 35.4 bits (80), Expect = 0.058
Identities = 45/213 (21%), Positives = 84/213 (39%), Gaps = 23/213 (10%)
Query: 27 DRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTA 86
DR E E++ F +++ EEV++ H + +ELE+ K
Sbjct: 2191 DRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDM 2250
Query: 87 NKVRSKLKSIEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCK 146
K+ GL +D + QH L KF +++ E E+
Sbjct: 2251 EKL---------------GLAIKESDAMSTQDQH-VLFGKFAQIIQEKEVEIDQLNEQVT 2294
Query: 147 GRIQRQLEITGRTTTSEELEDMLESGNPAIFASGIIMDSS-ISKQALSEIETRHSEIIKL 205
++Q+QL+IT EE +++ I ++ D + + EIE + I KL
Sbjct: 2295 -KLQQQLKITTDNKVIEEKNELIRDLETQI--ECLMSDQECVKRNREEEIEQLNEVIEKL 2351
Query: 206 ENSIRELHDMFMDMAMLVESQGEMIDRIEYNVE 238
+ +EL ++ +M S E D +++ ++
Sbjct: 2352 Q---QELANIGQKTSMNAHSLSEEADSLKHQLD 2381
Score = 33.5 bits (75), Expect = 0.22
Identities = 45/214 (21%), Positives = 92/214 (42%), Gaps = 21/214 (9%)
Query: 38 EEIRGFIDKIAENVEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKVRSKL--KS 95
++I G +++++ +E ++ + ++ N +L+ +I K + +S + KS
Sbjct: 665 QQIDGLQNEMSQKIETMQFEKDNLITKQN----------QLILEISKLKDLQQSLVNSKS 714
Query: 96 IEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCKGRIQR--QL 153
E +++ E L + LR + + TL ++ E+ + + +E+ ++ QL
Sbjct: 715 EEMTLQINE-LQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQL 773
Query: 154 EITGRTTTSEE--LEDMLESGNPAIFASGIIMDSSISKQALSEIETRHSEIIKLENSIRE 211
E E+ LEDML+ P +I SI ++ + + EI+ EN +
Sbjct: 774 EAENSILKDEKKTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEKEIEILIEEN--ED 831
Query: 212 LHDMFMDMAMLVESQGEMIDRIEYNVEHAVDYVE 245
L + + +E Q E N E V+Y E
Sbjct: 832 LKQQCIQLNEEIEKQRNTFSFAEKNFE--VNYQE 863
>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
Length = 1088
Score = 41.2 bits (95), Expect = 0.001
Identities = 42/219 (19%), Positives = 96/219 (43%), Gaps = 20/219 (9%)
Query: 25 DRDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSAILASPNPDEKTKEELEELMSDIKK 84
+++ +++ +Q++++ A + ++K N +K E L+E + D +K
Sbjct: 505 EKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEK 564
Query: 85 TANKVRSKLKSIEQSIEQ--------EEGLNRSSADLRIRKTQHSTLSRKFVEVMSEYNA 136
+ ++ ++KS++ EE L + K Q R+ E + Y
Sbjct: 565 QMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKK 624
Query: 137 TQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFASGIIMDSSISKQALSEIE 196
D +E+ +Q L + L D+ E + ++ +SG+ DS + ++ +E
Sbjct: 625 DLKDLKEKV-SLLQGDL-----SEKEASLLDLKEHAS-SLASSGLKKDSRLKTLEIA-LE 676
Query: 197 TRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEY 235
+ E +K+E+ +++ H + A+ + EM DRI++
Sbjct: 677 QKKEECLKMESQLKKAH----EAALEARASPEMSDRIQH 711
Score = 38.1 bits (87), Expect = 0.009
Identities = 61/298 (20%), Positives = 129/298 (43%), Gaps = 47/298 (15%)
Query: 1 MKDRTQELRTAKDSDDDDDVAVTVD-----RDRFMDEFFEQVE----EIRGFIDKIAENV 51
+K+R + L+ D+ + D T++ ++R ++ EQ + E + ID +++
Sbjct: 569 LKERVKSLQA--DTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDL 626
Query: 52 EEVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQ--EEGLNRS 109
+++K K S + + E + +L+E S + + K S+LK++E ++EQ EE L
Sbjct: 627 KDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKME 686
Query: 110 SADLRIRKTQHSTLSRKFVEVMS------EYNATQ-SDYRERCKGRIQRQLEITGRTTTS 162
S +++K + L + MS E T+ D + + + R LEI
Sbjct: 687 S---QLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENE 743
Query: 163 E--------ELEDMLESGNPAI--FASGIIMDSSISKQALSEIETRHSEI----IKLENS 208
+ ELE ++ N + ++ S Q L E R + +L++S
Sbjct: 744 KNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDS 803
Query: 209 IRELHDMFMDM------AMLVESQGEMI----DRIEYNVEHAVDYVERAVSDTKKAVK 256
+R+ D ++ ++ + ++ EM+ + N E V+ + A+ K+ ++
Sbjct: 804 LRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELE 861
Score = 35.8 bits (81), Expect = 0.045
Identities = 46/225 (20%), Positives = 95/225 (42%), Gaps = 25/225 (11%)
Query: 1 MKDRTQELRTAKDSDDDDDVAVTVDRDRFMDEFFEQVEEIRGFIDK-IAENVEEVKRKHS 59
M DR Q L D+ + DR + E ++VE + DK IAE +VK ++
Sbjct: 705 MSDRIQHLEREITRYKDESSKAQAEVDRLL-EILKEVENEKNDKDKKIAELERQVKDQNK 763
Query: 60 AILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSI--------EQEEGLNRS-- 109
+ + ++ K++ +++ + ++ + + + ++ S+ E EE L S
Sbjct: 764 KVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQ 823
Query: 110 -SADLRIRKTQHS---TLSRKFVE--------VMSEYNATQSDYRERCKGRIQRQLEITG 157
+A+ + Q T + K VE V E + ++ + +++ +T
Sbjct: 824 ITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTN 883
Query: 158 -RTTTSEELEDMLESGNPAIFASGIIMDSSISKQALSEIETRHSE 201
R + LE++LE A+ A+ D++I+ LS + + E
Sbjct: 884 LRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQE 928
Score = 30.8 bits (68), Expect = 1.4
Identities = 44/195 (22%), Positives = 86/195 (44%), Gaps = 25/195 (12%)
Query: 59 SAILASPNPDEKTKEELEELMSDIKKTANKV---RSKLKSIEQSIE-QEEGLNRSSADLR 114
S+ P E T+E + L ++ ++ A ++ R L+ +E IE Q++ LN ++
Sbjct: 251 SSRTGEPCVAELTEENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIK 310
Query: 115 --IRKTQHSTLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSEELE---DML 169
+ Q LS K AT+ D+ ER + + ++ + + E+ E ML
Sbjct: 311 KLLEMLQSKGLSAK---------ATEEDH-ERTRRLAEAEMHVHHLESLLEQKEKENSML 360
Query: 170 ESGNPAIFASGIIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDM----AMLVES 225
F + DS+ +K + IE + S+I +E +R+L + + A+ E
Sbjct: 361 REEMHRRFENA--PDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEE 418
Query: 226 QGEMIDRIEYNVEHA 240
+ E + ++E H+
Sbjct: 419 REEEMKQMEVYRSHS 433
>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
Length = 3907
Score = 41.2 bits (95), Expect = 0.001
Identities = 53/256 (20%), Positives = 115/256 (44%), Gaps = 35/256 (13%)
Query: 36 QVEEIRGFIDKIAENVEEVKRKHSAILASPNP-DEKTKEELEELMSD---IKKTANKVRS 91
+++E+ +I E E + R+ A+ A P +++ +E E+LM + ++ A KVR
Sbjct: 1958 RLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMKEKLEVQCQAEKVRD 2017
Query: 92 KLKS------------IEQSIEQEEGLNRSSADLRIRKT---QHSTLSRKFVEVMSEYNA 136
L+ + + IE E+ N DLR + + RKF++ +
Sbjct: 2018 DLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDRE 2077
Query: 137 TQSDYRERCKGRIQRQLEITGR--TTTSEELEDMLESGNPAIFASGIIMDSSISKQALS- 193
+ D ++ ++++QL++ R + + ++ + N + + +SK+ L
Sbjct: 2078 HERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQR 2137
Query: 194 EIETRHSEIIKLENSIRELHDMFMDMA------------MLVESQGEMIDRIEYNVEH-A 240
+I+ R+ EI KLE +REL + A VE++ E+ ++ E A
Sbjct: 2138 DIQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKHFGAVEAKPELSLEVQLQAERDA 2197
Query: 241 VDYVERAVSDTKKAVK 256
+D E+ +++ ++ ++
Sbjct: 2198 IDRKEKEITNLEEQLE 2213
Score = 37.7 bits (86), Expect = 0.012
Identities = 37/177 (20%), Positives = 79/177 (44%), Gaps = 12/177 (6%)
Query: 45 DKIAENVEEVKRKHSAILASPNPDEKTKEELEELM---SDIKKTANKVRSKLKSIEQSIE 101
++I + +E+K + S + ++ EE+++LM +++K +K I Q +E
Sbjct: 364 EQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRME 423
Query: 102 QEEGLNRSSADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTT 161
QE + + + + E++ ++ A + + R KG ++ L T
Sbjct: 424 QETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENALRSYSNITV 483
Query: 162 SEELEDMLESGNPAIFASGI-IMDSSISKQALSE-----IETRHSEIIKLENSIREL 212
+ ED ++ N AI I + D++ K+ L E +E + + +LE+ + EL
Sbjct: 484 N---EDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEEL 537
Score = 36.6 bits (83), Expect = 0.026
Identities = 32/116 (27%), Positives = 55/116 (47%), Gaps = 4/116 (3%)
Query: 50 NVEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRS 109
N+E++ H + L+S EKTK LEE + +++ + ++ +LK EQ+ E E +
Sbjct: 1313 NLEDIDVNHKSKLSSLQDLEKTK--LEEQVQELESLISSLQQQLKETEQNYEAEIHCLQK 1370
Query: 110 SADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRERC-KGRIQRQLEITGRTTTSEE 164
T +L V V++E +A ++ Y C K I +E +G EE
Sbjct: 1371 RLQAVSESTVPPSLPVDSV-VITESDAQRTMYPGSCVKKNIDGTIEFSGEFGVKEE 1425
Score = 35.4 bits (80), Expect = 0.058
Identities = 45/213 (21%), Positives = 84/213 (39%), Gaps = 23/213 (10%)
Query: 27 DRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTA 86
DR E E++ F +++ EEV++ H + +ELE+ K
Sbjct: 2199 DRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDM 2258
Query: 87 NKVRSKLKSIEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCK 146
K+ GL +D + QH L KF +++ E E+
Sbjct: 2259 EKL---------------GLAIKESDAMSTQDQH-VLFGKFAQIIQEKEVEIDQLNEQVT 2302
Query: 147 GRIQRQLEITGRTTTSEELEDMLESGNPAIFASGIIMDSS-ISKQALSEIETRHSEIIKL 205
++Q+QL+IT EE +++ I ++ D + + EIE + I KL
Sbjct: 2303 -KLQQQLKITTDNKVIEEKNELIRDLETQI--ECLMSDQECVKRNREEEIEQLNEVIEKL 2359
Query: 206 ENSIRELHDMFMDMAMLVESQGEMIDRIEYNVE 238
+ +EL ++ +M S E D +++ ++
Sbjct: 2360 Q---QELANIGQKTSMNAHSLSEEADSLKHQLD 2389
Score = 33.5 bits (75), Expect = 0.22
Identities = 45/214 (21%), Positives = 92/214 (42%), Gaps = 21/214 (9%)
Query: 38 EEIRGFIDKIAENVEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKVRSKL--KS 95
++I G +++++ +E ++ + ++ N +L+ +I K + +S + KS
Sbjct: 665 QQIDGLQNEMSQKIETMQFEKDNLITKQN----------QLILEISKLKDLQQSLVNSKS 714
Query: 96 IEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCKGRIQR--QL 153
E +++ E L + LR + + TL ++ E+ + + +E+ ++ QL
Sbjct: 715 EEMTLQINE-LQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQL 773
Query: 154 EITGRTTTSEE--LEDMLESGNPAIFASGIIMDSSISKQALSEIETRHSEIIKLENSIRE 211
E E+ LEDML+ P +I SI ++ + + EI+ EN +
Sbjct: 774 EAENSILKDEKKTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEKEIEILIEEN--ED 831
Query: 212 LHDMFMDMAMLVESQGEMIDRIEYNVEHAVDYVE 245
L + + +E Q E N E V+Y E
Sbjct: 832 LKQQCIQLNEEIEKQRNTFSFAEKNFE--VNYQE 863
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 41.2 bits (95), Expect = 0.001
Identities = 56/278 (20%), Positives = 118/278 (42%), Gaps = 30/278 (10%)
Query: 11 AKDSDDDDDVAVTVDRDRFMDEFFEQVEE-IRGFIDKIAE------NVEEVKRKHSAILA 63
AK +D++ V D++ + + + +EE I +AE N+ ++K KH ++++
Sbjct: 978 AKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMIS 1037
Query: 64 SPN----PDEKTKEELEELMSDIKKTANKVRSKLKSIEQSI--------EQEEGLNRSSA 111
+EK+++ELE+L ++ A+ ++ ++ I ++EE L + A
Sbjct: 1038 ELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALA 1097
Query: 112 DLRIRKTQHSTLSRKFVEVMSEYNATQSDY--RERCKGRIQRQLEITGR--TTTSEELED 167
L Q + +K E+ + Q D + + ++Q G ELED
Sbjct: 1098 RLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELED 1157
Query: 168 MLES-GNPAIFASGIIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQ 226
L+S + + ++ K+AL E ETR E ++E+ + Q
Sbjct: 1158 TLDSTATQQELRAKREQEVTVLKKALDE-ETRSHEA-----QVQEMRQKHAQAVEELTEQ 1211
Query: 227 GEMIDRIEYNVEHAVDYVERAVSDTKKAVKYQSKARRK 264
E R + N++ +E+ +D ++ +A+++
Sbjct: 1212 LEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQE 1249
Score = 35.8 bits (81), Expect = 0.045
Identities = 31/154 (20%), Positives = 63/154 (40%), Gaps = 11/154 (7%)
Query: 28 RFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTAN 87
R ++E E EE+ + +E++ + + + EK+K LE M ++K
Sbjct: 1490 RALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLE 1549
Query: 88 KVRSKLKSIEQS-----IEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMSEYNATQSDYR 142
++ +L++ E + + + + DL+ R Q+ R+ + EY D R
Sbjct: 1550 ELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDER 1609
Query: 143 ERCKGRIQRQLEITGRTTTSEELEDMLESGNPAI 176
+ QR L + +L+D+ + AI
Sbjct: 1610 K------QRALAAAAKKKLEGDLKDLELQADSAI 1637
Score = 31.2 bits (69), Expect = 1.1
Identities = 44/257 (17%), Positives = 104/257 (40%), Gaps = 31/257 (12%)
Query: 30 MDEFFEQVEEIRGFIDKIAENVEEVKRKHSAIL--------ASPNPDEKTK------EEL 75
++E EQ+E+ + + +N + ++++++ + A + K K +EL
Sbjct: 1205 VEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQEL 1264
Query: 76 EELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMSEYN 135
+ SD ++ ++ K+ ++ +E G+ + I+ L++ + S+
Sbjct: 1265 QSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIK------LAKDVASLSSQLQ 1318
Query: 136 ATQSDYRERCKGRIQ-----RQLEITGRTTTSEELEDMLESGNPAIFASGIIMDSSISKQ 190
TQ +E + ++ RQLE + + E+M N S + + S SK+
Sbjct: 1319 DTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKK 1378
Query: 191 ALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIE---YNVEHAVDYVERA 247
L + S + LE + ++ E + D++E ++ +D +
Sbjct: 1379 KLQDFA---STVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVD 1435
Query: 248 VSDTKKAVKYQSKARRK 264
+ + ++ V K +RK
Sbjct: 1436 LDNQRQLVSNLEKKQRK 1452
Score = 28.9 bits (63), Expect = 5.5
Identities = 49/270 (18%), Positives = 113/270 (41%), Gaps = 38/270 (14%)
Query: 1 MKDRTQELRTAKDSDDDDDVAVTVD--RDRFMDEFFEQVEEIRGFIDKIAENV----EEV 54
MKD +EL A+ S D+ + + + ++ Q++E ++ + EE+
Sbjct: 1654 MKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEEL 1713
Query: 55 KRKHSAILASPNP--DEKTK---------EELEELMSDIKKTANKVRSKLKSIEQSIEQE 103
+ ++ L+ N DEK + EELEE +++ +++VR + EQ + E
Sbjct: 1714 AEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQ-LSNE 1772
Query: 104 EGLNRSSADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSE 163
RS+A + ++ L R+ E+ S+ + + + + K I
Sbjct: 1773 LATERSTA--QKNESARQQLERQNKELRSKLHEMEGAVKSKFKS------TIAALEAKIA 1824
Query: 164 ELEDMLESGNPAIFASGIIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAMLV 223
+LE+ +E + + ++L + + + EI+ R++ + + + A
Sbjct: 1825 QLEEQVEQE---------AREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQA--- 1872
Query: 224 ESQGEMIDRIEYNVEHAVDYVERAVSDTKK 253
E + +++ +E A + +R ++ +K
Sbjct: 1873 EKGNARVKQLKRQLEEAEEESQRINANRRK 1902
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 41.2 bits (95), Expect = 0.001
Identities = 56/278 (20%), Positives = 118/278 (42%), Gaps = 30/278 (10%)
Query: 11 AKDSDDDDDVAVTVDRDRFMDEFFEQVEE-IRGFIDKIAE------NVEEVKRKHSAILA 63
AK +D++ V D++ + + + +EE I +AE N+ ++K KH ++++
Sbjct: 985 AKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMIS 1044
Query: 64 SPN----PDEKTKEELEELMSDIKKTANKVRSKLKSIEQSI--------EQEEGLNRSSA 111
+EK+++ELE+L ++ A+ ++ ++ I ++EE L + A
Sbjct: 1045 ELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALA 1104
Query: 112 DLRIRKTQHSTLSRKFVEVMSEYNATQSDY--RERCKGRIQRQLEITGR--TTTSEELED 167
L Q + +K E+ + Q D + + ++Q G ELED
Sbjct: 1105 RLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELED 1164
Query: 168 MLES-GNPAIFASGIIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQ 226
L+S + + ++ K+AL E ETR E ++E+ + Q
Sbjct: 1165 TLDSTATQQELRAKREQEVTVLKKALDE-ETRSHEA-----QVQEMRQKHAQAVEELTEQ 1218
Query: 227 GEMIDRIEYNVEHAVDYVERAVSDTKKAVKYQSKARRK 264
E R + N++ +E+ +D ++ +A+++
Sbjct: 1219 LEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQE 1256
Score = 35.8 bits (81), Expect = 0.045
Identities = 31/154 (20%), Positives = 63/154 (40%), Gaps = 11/154 (7%)
Query: 28 RFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTAN 87
R ++E E EE+ + +E++ + + + EK+K LE M ++K
Sbjct: 1497 RALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLE 1556
Query: 88 KVRSKLKSIEQS-----IEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMSEYNATQSDYR 142
++ +L++ E + + + + DL+ R Q+ R+ + EY D R
Sbjct: 1557 ELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDER 1616
Query: 143 ERCKGRIQRQLEITGRTTTSEELEDMLESGNPAI 176
+ QR L + +L+D+ + AI
Sbjct: 1617 K------QRALAAAAKKKLEGDLKDLELQADSAI 1644
Score = 31.2 bits (69), Expect = 1.1
Identities = 44/257 (17%), Positives = 104/257 (40%), Gaps = 31/257 (12%)
Query: 30 MDEFFEQVEEIRGFIDKIAENVEEVKRKHSAIL--------ASPNPDEKTK------EEL 75
++E EQ+E+ + + +N + ++++++ + A + K K +EL
Sbjct: 1212 VEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQEL 1271
Query: 76 EELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMSEYN 135
+ SD ++ ++ K+ ++ +E G+ + I+ L++ + S+
Sbjct: 1272 QSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIK------LAKDVASLSSQLQ 1325
Query: 136 ATQSDYRERCKGRIQ-----RQLEITGRTTTSEELEDMLESGNPAIFASGIIMDSSISKQ 190
TQ +E + ++ RQLE + + E+M N S + + S SK+
Sbjct: 1326 DTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKK 1385
Query: 191 ALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIE---YNVEHAVDYVERA 247
L + S + LE + ++ E + D++E ++ +D +
Sbjct: 1386 KLQDFA---STVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVD 1442
Query: 248 VSDTKKAVKYQSKARRK 264
+ + ++ V K +RK
Sbjct: 1443 LDNQRQLVSNLEKKQRK 1459
Score = 28.9 bits (63), Expect = 5.5
Identities = 49/270 (18%), Positives = 113/270 (41%), Gaps = 38/270 (14%)
Query: 1 MKDRTQELRTAKDSDDDDDVAVTVD--RDRFMDEFFEQVEEIRGFIDKIAENV----EEV 54
MKD +EL A+ S D+ + + + ++ Q++E ++ + EE+
Sbjct: 1661 MKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEEL 1720
Query: 55 KRKHSAILASPNP--DEKTK---------EELEELMSDIKKTANKVRSKLKSIEQSIEQE 103
+ ++ L+ N DEK + EELEE +++ +++VR + EQ + E
Sbjct: 1721 AEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQ-LSNE 1779
Query: 104 EGLNRSSADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSE 163
RS+A + ++ L R+ E+ S+ + + + + K I
Sbjct: 1780 LATERSTA--QKNESARQQLERQNKELRSKLHEMEGAVKSKFKS------TIAALEAKIA 1831
Query: 164 ELEDMLESGNPAIFASGIIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAMLV 223
+LE+ +E + + ++L + + + EI+ R++ + + + A
Sbjct: 1832 QLEEQVEQE---------AREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQA--- 1879
Query: 224 ESQGEMIDRIEYNVEHAVDYVERAVSDTKK 253
E + +++ +E A + +R ++ +K
Sbjct: 1880 EKGNARVKQLKRQLEEAEEESQRINANRRK 1909
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 41.2 bits (95), Expect = 0.001
Identities = 56/278 (20%), Positives = 118/278 (42%), Gaps = 30/278 (10%)
Query: 11 AKDSDDDDDVAVTVDRDRFMDEFFEQVEE-IRGFIDKIAE------NVEEVKRKHSAILA 63
AK +D++ V D++ + + + +EE I +AE N+ ++K KH ++++
Sbjct: 985 AKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMIS 1044
Query: 64 SPN----PDEKTKEELEELMSDIKKTANKVRSKLKSIEQSI--------EQEEGLNRSSA 111
+EK+++ELE+L ++ A+ ++ ++ I ++EE L + A
Sbjct: 1045 ELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALA 1104
Query: 112 DLRIRKTQHSTLSRKFVEVMSEYNATQSDY--RERCKGRIQRQLEITGR--TTTSEELED 167
L Q + +K E+ + Q D + + ++Q G ELED
Sbjct: 1105 RLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELED 1164
Query: 168 MLES-GNPAIFASGIIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQ 226
L+S + + ++ K+AL E ETR E ++E+ + Q
Sbjct: 1165 TLDSTATQQELRAKREQEVTVLKKALDE-ETRSHEA-----QVQEMRQKHAQAVEELTEQ 1218
Query: 227 GEMIDRIEYNVEHAVDYVERAVSDTKKAVKYQSKARRK 264
E R + N++ +E+ +D ++ +A+++
Sbjct: 1219 LEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQE 1256
Score = 35.8 bits (81), Expect = 0.045
Identities = 31/154 (20%), Positives = 63/154 (40%), Gaps = 11/154 (7%)
Query: 28 RFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTAN 87
R ++E E EE+ + +E++ + + + EK+K LE M ++K
Sbjct: 1497 RALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLE 1556
Query: 88 KVRSKLKSIEQS-----IEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMSEYNATQSDYR 142
++ +L++ E + + + + DL+ R Q+ R+ + EY D R
Sbjct: 1557 ELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDER 1616
Query: 143 ERCKGRIQRQLEITGRTTTSEELEDMLESGNPAI 176
+ QR L + +L+D+ + AI
Sbjct: 1617 K------QRALAAAAKKKLEGDLKDLELQADSAI 1644
Score = 31.2 bits (69), Expect = 1.1
Identities = 44/257 (17%), Positives = 104/257 (40%), Gaps = 31/257 (12%)
Query: 30 MDEFFEQVEEIRGFIDKIAENVEEVKRKHSAIL--------ASPNPDEKTK------EEL 75
++E EQ+E+ + + +N + ++++++ + A + K K +EL
Sbjct: 1212 VEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQEL 1271
Query: 76 EELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMSEYN 135
+ SD ++ ++ K+ ++ +E G+ + I+ L++ + S+
Sbjct: 1272 QSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIK------LAKDVASLSSQLQ 1325
Query: 136 ATQSDYRERCKGRIQ-----RQLEITGRTTTSEELEDMLESGNPAIFASGIIMDSSISKQ 190
TQ +E + ++ RQLE + + E+M N S + + S SK+
Sbjct: 1326 DTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKK 1385
Query: 191 ALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIE---YNVEHAVDYVERA 247
L + S + LE + ++ E + D++E ++ +D +
Sbjct: 1386 KLQDFA---STVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVD 1442
Query: 248 VSDTKKAVKYQSKARRK 264
+ + ++ V K +RK
Sbjct: 1443 LDNQRQLVSNLEKKQRK 1459
Score = 28.9 bits (63), Expect = 5.5
Identities = 49/270 (18%), Positives = 113/270 (41%), Gaps = 38/270 (14%)
Query: 1 MKDRTQELRTAKDSDDDDDVAVTVD--RDRFMDEFFEQVEEIRGFIDKIAENV----EEV 54
MKD +EL A+ S D+ + + + ++ Q++E ++ + EE+
Sbjct: 1661 MKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEEL 1720
Query: 55 KRKHSAILASPNP--DEKTK---------EELEELMSDIKKTANKVRSKLKSIEQSIEQE 103
+ ++ L+ N DEK + EELEE +++ +++VR + EQ + E
Sbjct: 1721 AEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQ-LSNE 1779
Query: 104 EGLNRSSADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSE 163
RS+A + ++ L R+ E+ S+ + + + + K I
Sbjct: 1780 LATERSTA--QKNESARQQLERQNKELRSKLHEMEGAVKSKFKS------TIAALEAKIA 1831
Query: 164 ELEDMLESGNPAIFASGIIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAMLV 223
+LE+ +E + + ++L + + + EI+ R++ + + + A
Sbjct: 1832 QLEEQVEQE---------AREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQA--- 1879
Query: 224 ESQGEMIDRIEYNVEHAVDYVERAVSDTKK 253
E + +++ +E A + +R ++ +K
Sbjct: 1880 EKGNARVKQLKRQLEEAEEESQRINANRRK 1909
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.129 0.338
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,657,001
Number of Sequences: 37866
Number of extensions: 342673
Number of successful extensions: 3100
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 103
Number of HSP's successfully gapped in prelim test: 384
Number of HSP's that attempted gapping in prelim test: 2302
Number of HSP's gapped (non-prelim): 1100
length of query: 288
length of database: 18,247,518
effective HSP length: 101
effective length of query: 187
effective length of database: 14,423,052
effective search space: 2697110724
effective search space used: 2697110724
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.