Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 4759144

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4759144 solute carrier family 9 (sodium/hydrogen exchanger),
isoform 5 [Homo sapiens]
         (896 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4759144 solute carrier family 9 (sodium/hydrogen exchanger), ...  1779   0.0  
gi|194239733 solute carrier family 9 (sodium/hydrogen exchanger)...   774   0.0  
gi|15529998 solute carrier family 9 (sodium/hydrogen exchanger),...   526   e-149
gi|27777632 solute carrier family 9, isoform A1 [Homo sapiens]        488   e-137
gi|148727259 solute carrier family 9 (sodium/hydrogen exchanger)...   462   e-130
gi|41872703 sodium/hydrogen exchanger 8 [Homo sapiens]                223   5e-58
gi|27734935 solute carrier family 9 (sodium/hydrogen exchanger),...   220   5e-57
gi|14211919 solute carrier family 9, member 7 [Homo sapiens]          192   2e-48
gi|5454070 solute carrier family 9 (sodium/hydrogen exchanger), ...   189   8e-48
gi|110227626 solute carrier family 9 (sodium/hydrogen exchanger)...   189   8e-48
gi|56786136 sperm-specific sodium proton exchanger [Homo sapiens]      52   3e-06
gi|38373682 pleckstrin homology domain containing family G membe...    44   9e-04
gi|111154084 pleckstrin homology domain containing family G memb...    44   9e-04
gi|111154088 pleckstrin homology domain containing family G memb...    44   9e-04
gi|111154080 pleckstrin homology domain containing family G memb...    44   9e-04
gi|111154078 pleckstrin homology domain containing family G memb...    44   9e-04
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]         40   0.013
gi|45359846 Ras-GTPase activating protein SH3 domain-binding pro...    37   0.082
gi|28274705 family with sequence similarity 9, member A [Homo sa...    37   0.082
gi|4757816 ATPase, H+ transporting, lysosomal 21kDa, V0 subunit ...    37   0.082
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]    37   0.11 
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ...    36   0.14 
gi|209862789 microtubule associated monoxygenase, calponin and L...    36   0.14 
gi|119964726 insulin-like growth factor 2 receptor precursor [Ho...    36   0.18 
gi|86792634 ATPase, H+ transporting, lysosomal 21kDa, V0 subunit...    36   0.18 
gi|157384971 cyclin G associated kinase [Homo sapiens]                 35   0.24 
gi|183396783 BCL-6 interacting corepressor isoform a [Homo sapiens]    35   0.24 
gi|183396787 BCL-6 interacting corepressor isoform c [Homo sapiens]    35   0.24 
gi|183396785 BCL-6 interacting corepressor isoform b [Homo sapiens]    35   0.24 
gi|21071037 BCL-6 interacting corepressor isoform a [Homo sapiens]     35   0.24 

>gi|4759144 solute carrier family 9 (sodium/hydrogen exchanger),
           isoform 5 [Homo sapiens]
          Length = 896

 Score = 1779 bits (4607), Expect = 0.0
 Identities = 896/896 (100%), Positives = 896/896 (100%)

Query: 1   MLRAALSLLALPLAGAAEEPTQKPESPGEPPPGLELFRWQWHEVEAPYLVALWILVASLA 60
           MLRAALSLLALPLAGAAEEPTQKPESPGEPPPGLELFRWQWHEVEAPYLVALWILVASLA
Sbjct: 1   MLRAALSLLALPLAGAAEEPTQKPESPGEPPPGLELFRWQWHEVEAPYLVALWILVASLA 60

Query: 61  KIVFHLSRKVTSLVPESCLLILLGLVLGGIVLAVAKKAEYQLEPGTFFLFLLPPIVLDSG 120
           KIVFHLSRKVTSLVPESCLLILLGLVLGGIVLAVAKKAEYQLEPGTFFLFLLPPIVLDSG
Sbjct: 61  KIVFHLSRKVTSLVPESCLLILLGLVLGGIVLAVAKKAEYQLEPGTFFLFLLPPIVLDSG 120

Query: 121 YFMPSRLFFDNLGAILTYAVVGTLWNAFTTGAALWGLQQAGLVAPRVQAGLLDFLLFGSL 180
           YFMPSRLFFDNLGAILTYAVVGTLWNAFTTGAALWGLQQAGLVAPRVQAGLLDFLLFGSL
Sbjct: 121 YFMPSRLFFDNLGAILTYAVVGTLWNAFTTGAALWGLQQAGLVAPRVQAGLLDFLLFGSL 180

Query: 181 ISAVDPVAVLAVFEEVHVNETLFIIVFGESLLNDAVTVVLYKVCNSFVEMGSANVQATDY 240
           ISAVDPVAVLAVFEEVHVNETLFIIVFGESLLNDAVTVVLYKVCNSFVEMGSANVQATDY
Sbjct: 181 ISAVDPVAVLAVFEEVHVNETLFIIVFGESLLNDAVTVVLYKVCNSFVEMGSANVQATDY 240

Query: 241 LKGVASLFVVSLGGAAVGLVFAFLLALTTRFTKRVRIIEPLLVFLLAYAAYLTAEMASLS 300
           LKGVASLFVVSLGGAAVGLVFAFLLALTTRFTKRVRIIEPLLVFLLAYAAYLTAEMASLS
Sbjct: 241 LKGVASLFVVSLGGAAVGLVFAFLLALTTRFTKRVRIIEPLLVFLLAYAAYLTAEMASLS 300

Query: 301 AILAVTMCGLGCKKYVEANISHKSRTTVKYTMKTLASCAETVIFMLLGISAVDSSKWAWD 360
           AILAVTMCGLGCKKYVEANISHKSRTTVKYTMKTLASCAETVIFMLLGISAVDSSKWAWD
Sbjct: 301 AILAVTMCGLGCKKYVEANISHKSRTTVKYTMKTLASCAETVIFMLLGISAVDSSKWAWD 360

Query: 361 SGLVLGTLIFILFFRALGVVLQTWVLNQFRLVPLDKIDQVVMSYGGLRGAVAFALVILLD 420
           SGLVLGTLIFILFFRALGVVLQTWVLNQFRLVPLDKIDQVVMSYGGLRGAVAFALVILLD
Sbjct: 361 SGLVLGTLIFILFFRALGVVLQTWVLNQFRLVPLDKIDQVVMSYGGLRGAVAFALVILLD 420

Query: 421 RTKVPAKDYFVATTIVVVFFTVIVQGLTIKPLVKWLKVKRSEHHKPTLNQELHEHTFDHI 480
           RTKVPAKDYFVATTIVVVFFTVIVQGLTIKPLVKWLKVKRSEHHKPTLNQELHEHTFDHI
Sbjct: 421 RTKVPAKDYFVATTIVVVFFTVIVQGLTIKPLVKWLKVKRSEHHKPTLNQELHEHTFDHI 480

Query: 481 LAAVEDVVGHHGYHYWRDRWEQFDKKYLSQLLMRRSAYRIRDQIWDVYYRLNIRDAISFV 540
           LAAVEDVVGHHGYHYWRDRWEQFDKKYLSQLLMRRSAYRIRDQIWDVYYRLNIRDAISFV
Sbjct: 481 LAAVEDVVGHHGYHYWRDRWEQFDKKYLSQLLMRRSAYRIRDQIWDVYYRLNIRDAISFV 540

Query: 541 DQGGHVLSSTGLTLPSMPSRNSVAETSVTNLLRESGSGACLDLQVIDTVRSGRDREDAVM 600
           DQGGHVLSSTGLTLPSMPSRNSVAETSVTNLLRESGSGACLDLQVIDTVRSGRDREDAVM
Sbjct: 541 DQGGHVLSSTGLTLPSMPSRNSVAETSVTNLLRESGSGACLDLQVIDTVRSGRDREDAVM 600

Query: 601 HHLLCGGLYKPRRRYKASCSRHFISEDAQERQDKEVFQQNMKRRLESFKSTKHNICFTKS 660
           HHLLCGGLYKPRRRYKASCSRHFISEDAQERQDKEVFQQNMKRRLESFKSTKHNICFTKS
Sbjct: 601 HHLLCGGLYKPRRRYKASCSRHFISEDAQERQDKEVFQQNMKRRLESFKSTKHNICFTKS 660

Query: 661 KPRPRKTGRRKKDGVANAEATNGKHRGLGFQDTAAVILTVESEEEEEESDSSETEKEDDE 720
           KPRPRKTGRRKKDGVANAEATNGKHRGLGFQDTAAVILTVESEEEEEESDSSETEKEDDE
Sbjct: 661 KPRPRKTGRRKKDGVANAEATNGKHRGLGFQDTAAVILTVESEEEEEESDSSETEKEDDE 720

Query: 721 GIIFVARATSEVLQEGKVSGSLEVCPSPRIIPPSPTCAEKELPWKSGQGDLAVYVSSETT 780
           GIIFVARATSEVLQEGKVSGSLEVCPSPRIIPPSPTCAEKELPWKSGQGDLAVYVSSETT
Sbjct: 721 GIIFVARATSEVLQEGKVSGSLEVCPSPRIIPPSPTCAEKELPWKSGQGDLAVYVSSETT 780

Query: 781 KIVPVDMQTGWNQSISSLESLASPPCNQAPILTCLPPHPRGTEEPQVPLHLPSDPRSSFA 840
           KIVPVDMQTGWNQSISSLESLASPPCNQAPILTCLPPHPRGTEEPQVPLHLPSDPRSSFA
Sbjct: 781 KIVPVDMQTGWNQSISSLESLASPPCNQAPILTCLPPHPRGTEEPQVPLHLPSDPRSSFA 840

Query: 841 FPPSLAKAGRSRSESSADLPQQQELQPLMGHKDHTHLSPGTATSHWCIQFNRGSRL 896
           FPPSLAKAGRSRSESSADLPQQQELQPLMGHKDHTHLSPGTATSHWCIQFNRGSRL
Sbjct: 841 FPPSLAKAGRSRSESSADLPQQQELQPLMGHKDHTHLSPGTATSHWCIQFNRGSRL 896


>gi|194239733 solute carrier family 9 (sodium/hydrogen exchanger),
           isoform 3 [Homo sapiens]
          Length = 834

 Score =  774 bits (1999), Expect = 0.0
 Identities = 424/742 (57%), Positives = 535/742 (72%), Gaps = 22/742 (2%)

Query: 8   LLALPLAGAAEEPTQKPESPGE--PPPGLELFRWQWHEVEAPYLVALWILVASLAKIVFH 65
           LLAL L G A     + E  G      G ++  ++W  V+ PY++ALWILVASLAKI FH
Sbjct: 14  LLALALGGLARAGGVEVEPGGAHGESGGFQVVTFEWAHVQDPYVIALWILVASLAKIGFH 73

Query: 66  LSRKVTSLVPESCLLILLGLVLGGIVLAVAKKAEYQLEPGTFFLFLLPPIVLDSGYFMPS 125
           LS KVTS+VPES LLI+LGLVLGGIV A    A + L P  FF +LLPPIVLD+GYFMP+
Sbjct: 74  LSHKVTSVVPESALLIVLGLVLGGIVWAADHIASFTLTPTVFFFYLLPPIVLDAGYFMPN 133

Query: 126 RLFFDNLGAILTYAVVGTLWNAFTTGAALWGLQQAGLVAPRVQAGLLDFLLFGSLISAVD 185
           RLFF NLG IL YAVVGT+WNA TTG +L+G+  +GL+   +Q GLLDFLLFGSL++AVD
Sbjct: 134 RLFFGNLGTILLYAVVGTVWNAATTGLSLYGVFLSGLMGD-LQIGLLDFLLFGSLMAAVD 192

Query: 186 PVAVLAVFEEVHVNETLFIIVFGESLLNDAVTVVLYKVCNSFVEMGSANVQATDYLKGVA 245
           PVAVLAVFEEVHVNE LFIIVFGESLLNDAVTVVLY V  SFV +G  NV   D +KG+ 
Sbjct: 193 PVAVLAVFEEVHVNEVLFIIVFGESLLNDAVTVVLYNVFESFVALGGDNVTGVDCVKGIV 252

Query: 246 SLFVVSLGGAAVGLVFAFLLALTTRFTKRVRIIEPLLVFLLAYAAYLTAEMASLSAILAV 305
           S FVVSLGG  VG+VFAFLL+L TRFTK VRIIEP  VF+++Y +YLT+EM SLSAILA+
Sbjct: 253 SFFVVSLGGTLVGVVFAFLLSLVTRFTKHVRIIEPGFVFIISYLSYLTSEMLSLSAILAI 312

Query: 306 TMCGLGCKKYVEANISHKSRTTVKYTMKTLASCAETVIFMLLGISAVDSSKWAWDSGLVL 365
           T CG+ C+KYV+ANIS +S TTV+YTMK LAS AET+IFM LGISAV+   W W++  VL
Sbjct: 313 TFCGICCQKYVKANISEQSATTVRYTMKMLASSAETIIFMFLGISAVNPFIWTWNTAFVL 372

Query: 366 GTLIFILFFRALGVVLQTWVLNQFRLVPLDKIDQVVMSYGGLRGAVAFALVILLDRTKVP 425
            TL+FI  +RA+GVVLQTW+LN++R+V L+ IDQVV+SYGGLRGAVAFALV+LLD  KV 
Sbjct: 373 LTLVFISVYRAIGVVLQTWLLNRYRMVQLEPIDQVVLSYGGLRGAVAFALVVLLDGDKVK 432

Query: 426 AKDYFVATTIVVVFFTVIVQGLTIKPLVKWLKVKRSEHHKPTLNQELHEHTFDHILAAVE 485
            K+ FV+TTI+VVFFTVI QGLTIKPLV+WLKVKRSEH +P LN++LH   FDHIL+A+E
Sbjct: 433 EKNLFVSTTIIVVFFTVIFQGLTIKPLVQWLKVKRSEHREPRLNEKLHGRAFDHILSAIE 492

Query: 486 DVVGHHGYHYWRDRWEQFDKKYLSQLLMRRSAYRIRDQIWDVYYRLNIRDAISFVDQGGH 545
           D+ G  G++Y RD+W  FD+K+LS++LMRRSA + RD+I +V++ LN++DAIS+V +G  
Sbjct: 493 DISGQIGHNYLRDKWSHFDRKFLSRVLMRRSAQKSRDRILNVFHELNLKDAISYVAEGER 552

Query: 546 VLSSTGLTLPSMPS--------RNSVAETSVTNLLRESGSGACLDLQVID-TVRSGRDRE 596
             S   +  PS  +        R+S  E SV+ LLRE+ S  CLD+Q ++   RS RD E
Sbjct: 553 RGSLAFIRSPSTDNVVNVDFTPRSSTVEASVSYLLRENVSAVCLDMQSLEQRRRSIRDAE 612

Query: 597 DAVMHHLLCGGLYKPRRRYKASCSRHFISEDAQERQDKEVFQQNMKRRLESFKSTKHNIC 656
           D V HH L   LYKPR+ YK   SRH ++    E+QD+E+F + M++RLESFKSTK  + 
Sbjct: 613 DMVTHHTLQQYLYKPRQEYKHLYSRHELTPTEDEKQDREIFHRTMRKRLESFKSTKLGLN 672

Query: 657 FTKSKPRPRKTGRRKKDGVANAEATNGKHRGLGFQDTAAVILTVESEEEEEESDSSETEK 716
             K   +  K  R +K    N+   NGK       ++ A   T++ E++ E SD+ E   
Sbjct: 673 QNKKAAKLYKRERAQKR--RNSSIPNGKLP----MESPAQNFTIK-EKDLELSDTEEPPN 725

Query: 717 EDDE---GIIFVARATSEVLQE 735
            D+E   GI F+A  T +   +
Sbjct: 726 YDEEMSGGIEFLASVTKDTASD 747


>gi|15529998 solute carrier family 9 (sodium/hydrogen exchanger),
           member 2 [Homo sapiens]
          Length = 812

 Score =  526 bits (1355), Expect = e-149
 Identities = 310/755 (41%), Positives = 441/755 (58%), Gaps = 71/755 (9%)

Query: 1   MLRAALSLLALPLAGAAEEPTQKPESPG---EPP-------PG--------LELFRWQWH 42
           ML   L  +A P+   AE     P + G    PP       PG        L +F   + 
Sbjct: 17  MLLLLLLQVAGPVGALAETLLNAPRAMGTSSSPPSPASVVAPGTTLFEESRLPVFTLDYP 76

Query: 43  EVEAPYLVALWILVASLAKIVFHLSRKVTSLVPESCLLILLGLVLGGIVLAVAKKAEYQL 102
            V+ P+ + LWIL+ASLAKI FHL  K+ ++VPESCLLI++GL+LGGI+  V +K+   +
Sbjct: 77  HVQIPFEITLWILLASLAKIGFHLYHKLPTIVPESCLLIMVGLLLGGIIFGVDEKSPPAM 136

Query: 103 EPGTFFLFLLPPIVLDSGYFMPSRLFFDNLGAILTYAVVGTLWNAFTTGAALWGLQQAGL 162
           +   FFL+LLPPIVLD+GYFMP+R FF+N+G I  YAVVGTLWN+   G +L+G+ Q   
Sbjct: 137 KTDVFFLYLLPPIVLDAGYFMPTRPFFENIGTIFWYAVVGTLWNSIGIGVSLFGICQIEA 196

Query: 163 VAPRVQAGLLDFLLFGSLISAVDPVAVLAVFEEVHVNETLFIIVFGESLLNDAVTVVLYK 222
                   LL  LLFGSLISAVDPVAVLAVFE +HVNE L+I+VFGESLLNDAVTVVLY 
Sbjct: 197 FGLS-DITLLQNLLFGSLISAVDPVAVLAVFENIHVNEQLYILVFGESLLNDAVTVVLYN 255

Query: 223 VCNSFVEMGSANVQATDYLKGVASLFVVSLGGAAVGLVFAFLLALTTRFTKRVRIIEPLL 282
           +  SF +M +  ++  D   G+A+ FVV +GG  +G+   F+ A TTRFT  +R+IEPL 
Sbjct: 256 LFKSFCQMKT--IETIDVFAGIANFFVVGIGGVLIGIFLGFIAAFTTRFTHNIRVIEPLF 313

Query: 283 VFLLAYAAYLTAEMASLSAILAVTMCGLGCKKYVEANISHKSRTTVKYTMKTLASCAETV 342
           VFL +Y +Y+TAEM  LS I+A+T C +   KYVE N+S KS TT+KY MK L+S +ET+
Sbjct: 314 VFLYSYLSYITAEMFHLSGIMAITACAMTMNKYVEENVSQKSYTTIKYFMKMLSSVSETL 373

Query: 343 IFMLLGISAVDSS-KWAWDSGLVLGTLIFILFFRALGVVLQTWVLNQFRLVPLDKIDQVV 401
           IF+ +G+S V  + +W W    V  TL F L +RALGV + T V+N+FR +PL   DQ +
Sbjct: 374 IFIFMGVSTVGKNHEWNW--AFVCFTLAFCLMWRALGVFVLTQVINRFRTIPLTFKDQFI 431

Query: 402 MSYGGLRGAVAFALVILLDRTKVPAKDYFVATTIVVVFFTVIVQGLTIKPLVKWLKVKRS 461
           ++YGGLRGA+ FALV LL     P K  F+   IVV+FFTV + G+TI+PLV++L VKRS
Sbjct: 432 IAYGGLRGAICFALVFLLPAAVFPRKKLFITAAIVVIFFTVFILGITIRPLVEFLDVKRS 491

Query: 462 EHHKPTLNQELHEHTFDHILAAVEDVVGHHGYHYWRDRWEQFDKKYLSQLLMRRSAYRIR 521
              +  +++E++   FDH+   +EDV GH G+++WRD++++FD KYL +LL+R +  + +
Sbjct: 492 NKKQQAVSEEIYCRLFDHVKTGIEDVCGHWGHNFWRDKFKKFDDKYLRKLLIREN--QPK 549

Query: 522 DQIWDVYYRLNIRDAISFVDQGGHVLSSTGLTLPSMPSRNSVAETSVTNLLRESGSGACL 581
             I  +Y +L I+ AI   + G  ++S    T+P+  S N   E                
Sbjct: 550 SSIVSLYKKLEIKHAIEMAETG--MIS----TVPTFASLNDCRE---------------- 587

Query: 582 DLQVIDTVRSGRDREDAVMHHLLCGGLYKPRRRYKASCSRHFISEDAQERQDKEVF---- 637
                + +R     E   +  LL   LY+ R+R   S +RH ++ D  ERQ KE+     
Sbjct: 588 -----EKIRKVTSSETDEIRELLSRNLYQIRQR-TLSYNRHSLTADTSERQAKEILIRRR 641

Query: 638 ---------QQNMKRRLESFKSTKHNICFTKSKPRPRKTGRRKKDGVANAEATNGKHRG- 687
                      ++ R   +  ST   +   K+   P K  +R+   +A+  +++      
Sbjct: 642 HSLRESIRKDSSLNREHRASTSTSRYLSLPKNTKLPEKLQKRRTISIADGNSSDSDADAG 701

Query: 688 ---LGFQDTAAVILTVESEEEEEESDSSETEKEDD 719
              L  Q  A   L  +  ++  +S   E + E D
Sbjct: 702 TTVLNLQPRARRFLPEQFSKKSPQSYKMEWKNEVD 736


>gi|27777632 solute carrier family 9, isoform A1 [Homo sapiens]
          Length = 815

 Score =  488 bits (1256), Expect = e-137
 Identities = 272/602 (45%), Positives = 387/602 (64%), Gaps = 27/602 (4%)

Query: 44  VEAPYLVALWILVASLAKIVFHLSRKVTSLVPESCLLILLGLVLGGIVLAVAKKAEYQLE 103
           V  P+ ++LWIL+A L KI FH+   ++S+VPESCLLI++GL++GG++  V +   + L+
Sbjct: 99  VRTPFEISLWILLACLMKIGFHVIPTISSIVPESCLLIVVGLLVGGLIKGVGETPPF-LQ 157

Query: 104 PGTFFLFLLPPIVLDSGYFMPSRLFFDNLGAILTYAVVGTLWNAFTTGAALWGLQQAGLV 163
              FFLFLLPPI+LD+GYF+P R F +NLG IL +AVVGTLWNAF  G  ++ +   G  
Sbjct: 158 SDVFFLFLLPPIILDAGYFLPLRQFTENLGTILIFAVVGTLWNAFFLGGLMYAVCLVGGE 217

Query: 164 APRVQAGLLDFLLFGSLISAVDPVAVLAVFEEVHVNETLFIIVFGESLLNDAVTVVLYKV 223
                 GLLD LLFGS+ISAVDPVAVLAVFEE+H+NE L I+VFGESLLNDAVTVVLY +
Sbjct: 218 QIN-NIGLLDNLLFGSIISAVDPVAVLAVFEEIHINELLHILVFGESLLNDAVTVVLYHL 276

Query: 224 CNSFVEMGSANVQATDYLKGVASLFVVSLGGAAVGLVFAFLLALTTRFTKRVRIIEPLLV 283
              F      +V   D   G  S FVV+LGG  VG+V+  + A T+RFT  +R+IEPL V
Sbjct: 277 FEEFANY--EHVGIVDIFLGFLSFFVVALGGVLVGVVYGVIAAFTSRFTSHIRVIEPLFV 334

Query: 284 FLLAYAAYLTAEMASLSAILAVTMCGLGCKKYVEANISHKSRTTVKYTMKTLASCAETVI 343
           FL +Y AYL+AE+  LS I+A+   G+  + YVEANISHKS TT+KY +K  +S +ET+I
Sbjct: 335 FLYSYMAYLSAELFHLSGIMALIASGVVMRPYVEANISHKSHTTIKYFLKMWSSVSETLI 394

Query: 344 FMLLGISAVDSSK-WAWDSGLVLGTLIFILFFRALGVVLQTWVLNQFRLVPLDKIDQVVM 402
           F+ LG+S V  S  W W    V+ TL+F L  R LGV+  TW +N+FR+V L   DQ ++
Sbjct: 395 FIFLGVSTVAGSHHWNWT--FVISTLLFCLIARVLGVLGLTWFINKFRIVKLTPKDQFII 452

Query: 403 SYGGLRGAVAFALVILLDRTKVPAKDYFVATTIVVVFFTVIVQGLTIKPLVKWLKVKRSE 462
           +YGGLRGA+AF+L  LLD+   P  D F+   I V+FFTV VQG+TI+PLV  L VK+ +
Sbjct: 453 AYGGLRGAIAFSLGYLLDKKHFPMCDLFLTAIITVIFFTVFVQGMTIRPLVDLLAVKKKQ 512

Query: 463 HHKPTLNQELHEHTFDHILAAVEDVVGHHGYHYWRDRWEQFDKKYLSQLLMRRSAYRIRD 522
             K ++N+E+H    DH+L  +ED+ GH+G+H+W+D+  +F+KKY+ + L+     +   
Sbjct: 513 ETKRSINEEIHTQFLDHLLTGIEDICGHYGHHHWKDKLNRFNKKYVKKCLIAGERSK-EP 571

Query: 523 QIWDVYYRLNIRDAISFVDQGGHVLSSTGLTLPSMPSRNSVAETSVTNLLRESGSGACLD 582
           Q+   Y+++ ++ AI  V+ GG         +  +PS  +V+  S+ N+  +S     L 
Sbjct: 572 QLIAFYHKMEMKQAIELVESGG---------MGKIPS--AVSTVSMQNIHPKS-----LP 615

Query: 583 LQVIDTVRSGRDREDAVMHHLLCGGLYKPRRRYKASCSRHFISEDAQERQDKEVFQQNMK 642
            + I    S +D+E+ +   +L   L K R+R + S +RH +  D  E    ++  +  K
Sbjct: 616 SERILPALS-KDKEEEI-RKILRNNLQKTRQRLR-SYNRHTLVADPYEEAWNQMLLRRQK 672

Query: 643 RR 644
            R
Sbjct: 673 AR 674


>gi|148727259 solute carrier family 9 (sodium/hydrogen exchanger),
           member 4 [Homo sapiens]
          Length = 798

 Score =  462 bits (1189), Expect = e-130
 Identities = 269/666 (40%), Positives = 396/666 (59%), Gaps = 39/666 (5%)

Query: 29  EPPPGLELFRWQWHEVEAPYLVALWILVASLAKIVFHLSRKVTSLVPESCLLILLGLVLG 88
           EP  G+ +F   +  V+ PY V LWIL+ASLAKI FHL  ++  L+PESCLLIL+G ++G
Sbjct: 52  EPEEGISVFELDYDYVQIPYEVTLWILLASLAKIGFHLYHRLPGLMPESCLLILVGALVG 111

Query: 89  GIVLAVAKKAEYQLEPGTFFLFLLPPIVLDSGYFMPSRLFFDNLGAILTYAVVGTLWNAF 148
           GI+     K+   ++   +FL+LLPPIVL+ GYFMP+R FF+N+G+IL +AV+G L NA 
Sbjct: 112 GIIFGTDHKSPPVMDSSIYFLYLLPPIVLEGGYFMPTRPFFENIGSILWWAVLGALINAL 171

Query: 149 TTGAALWGLQQAGLVAPRVQAGLLDFLLFGSLISAVDPVAVLAVFEEVHVNETLFIIVFG 208
             G +L+ + Q           LL  LLFGSLISAVDPVAVLAVFEE  VNE L++++FG
Sbjct: 172 GIGLSLYLICQVKAFG-LGDVNLLQNLLFGSLISAVDPVAVLAVFEEARVNEQLYMMIFG 230

Query: 209 ESLLNDAVTVVLYKVCNSFVEMGS-ANVQATDYLKGVASLFVVSLGGAAVGLVFAFLLAL 267
           E+LLND +TVVLY +  +F +M    +++  D L G A   VV LGG   G+VF F+ A 
Sbjct: 231 EALLNDGITVVLYNMLIAFTKMHKFEDIETVDILAGCARFIVVGLGGVLFGIVFGFISAF 290

Query: 268 TTRFTKRVRIIEPLLVFLLAYAAYLTAEMASLSAILAVTMCGLGCKKYVEANISHKSRTT 327
            TRFT+ +  IEPL+VF+ +Y +YL AE   LS ILA+T C +  KKYVE N+S  S TT
Sbjct: 291 ITRFTQNISAIEPLIVFMFSYLSYLAAETLYLSGILAITACAVTMKKYVEENVSQTSYTT 350

Query: 328 VKYTMKTLASCAETVIFMLLGISAVDSS-KWAWDSGLVLGTLIFILFFRALGVVLQTWVL 386
           +KY MK L+S +ET+IF+ +G+S V  + +W W    +  TL F   +RA+ V    ++ 
Sbjct: 351 IKYFMKMLSSVSETLIFIFMGVSTVGKNHEWNW--AFICFTLAFCQIWRAISVFALFYIS 408

Query: 387 NQFRLVPLDKIDQVVMSYGGLRGAVAFALVILLDRTKVPAKDYFVATTIVVVFFTVIVQG 446
           NQFR  P    DQ ++ Y G+RGA +F+L  LL  +  P K  FV  T+VV++FTV +QG
Sbjct: 409 NQFRTFPFSIKDQCIIFYSGVRGAGSFSLAFLLPLSLFPRKKMFVTATLVVIYFTVFIQG 468

Query: 447 LTIKPLVKWLKVKRSEHHKPTLNQELHEHTFDHILAAVEDVVGHHGYHYWRDRWEQFDKK 506
           +T+ PLV++L VK++ + K ++N+ELH    DH+ A +EDV GH  ++  RD++++FD +
Sbjct: 469 ITVGPLVRYLDVKKT-NKKESINEELHIRLMDHLKAGIEDVCGHWSHYQVRDKFKKFDHR 527

Query: 507 YLSQLLMRRSAYRIRDQIWDVYYRLNIRDAISFVDQGGHVLSSTGLTLPSMPSRNSVAET 566
           YL ++L+R++    +  I  +Y +L ++ AI  V+ G  +LSST  ++P    R      
Sbjct: 528 YLRKILIRKNL--PKSSIVSLYKKLEMKQAIEMVETG--ILSSTAFSIPHQAQR------ 577

Query: 567 SVTNLLRESGSGACLDLQVIDTVRSGRDREDAVMHHLLCGGLYKPRRRYKASCSRHFISE 626
            +  + R S           + V S RD        +L   +Y+ R+R   S +++ +  
Sbjct: 578 -IQGIKRLSP----------EDVESIRD--------ILTSNMYQVRQR-TLSYNKYNLKP 617

Query: 627 DAQERQDKEVFQQNMKRRLESFKSTKHNICFTKSKPRPRKTGRRKKDGVANAEATNGKHR 686
              E+Q KE+  +      ES +   H++ +   KP   K  R       N ++     R
Sbjct: 618 QTSEKQAKEILIRRQNTLRESMRK-GHSLPW--GKPAGTKNIRYLSYPYGNPQSAGRDTR 674

Query: 687 GLGFQD 692
             GF D
Sbjct: 675 AAGFSD 680


>gi|41872703 sodium/hydrogen exchanger 8 [Homo sapiens]
          Length = 581

 Score =  223 bits (569), Expect = 5e-58
 Identities = 143/467 (30%), Positives = 243/467 (52%), Gaps = 26/467 (5%)

Query: 9   LALPLAGAAEEPTQKPESPGEPPPGLELFRWQWHEVEAPYLVALWILVASLAKIVFHLS- 67
           L LP  G    P Q  E              Q  E  +   +   +LV ++  I+ HL  
Sbjct: 33  LVLPTPGKPILPVQTGEQA------------QQEEQSSGMTIFFSLLVLAICIILVHLLI 80

Query: 68  RKVTSLVPESCLLILLGLVLGGIVLAVAKKA------EYQLEPGTFFLFLLPPIVLDSGY 121
           R     +PES  ++ LG+++G ++  +  K       E    P  FFL LLPPI+ +SGY
Sbjct: 81  RYRLHFLPESVAVVSLGILMGAVIKIIEFKKLANWKEEEMFRPNMFFLLLLPPIIFESGY 140

Query: 122 FMPSRLFFDNLGAILTYAVVGTLWNAFTTGAALWGLQQAGLVAPRVQAGLLDFLLFGSLI 181
            +    FF N+G+I  +AV GT  +AF  G  ++ L QA +++   +  + D   FGSLI
Sbjct: 141 SLHKGNFFQNIGSITLFAVFGTAISAFVVGGGIYFLGQADVIS---KLNMTDSFAFGSLI 197

Query: 182 SAVDPVAVLAVFEEVHVNETLFIIVFGESLLNDAVTVVLYKVCNSFVEMGSANVQA-TDY 240
           SAVDPVA +A+F  +HV+  L ++VFGES+LNDAV++VL            ++V     +
Sbjct: 198 SAVDPVATIAIFNALHVDPVLNMLVFGESILNDAVSIVLTNTAEGLTRKNMSDVSGWQTF 257

Query: 241 LKGVASLFVVSLGGAAVGLVFAFLLALTTRF--TKRVRIIEPLLVFLLAYAAYLTAEMAS 298
           L+ +     +  G AA+G +   + AL  +    ++   +E  ++ + AY  Y  AE  S
Sbjct: 258 LQALDYFLKMFFGSAALGTLTGLISALVLKHIDLRKTPSLEFGMMIIFAYLPYGLAEGIS 317

Query: 299 LSAILAVTMCGLGCKKYVEANISHKSRTTVKYTMKTLASCAETVIFMLLGISAVDSSKWA 358
           LS I+A+   G+    Y   N+S  ++  ++ T++T+A   ET +F  LG+S + S    
Sbjct: 318 LSGIMAILFSGIVMSHYTHHNLSPVTQILMQQTLRTVAFLCETCVFAFLGLS-IFSFPHK 376

Query: 359 WDSGLVLGTLIFILFFRALGVVLQTWVLNQFRLVPLDKIDQVVMSYGGLRGAVAFALVIL 418
           ++   V+  ++ +LF RA+ +   +++LN FR   +      +M + GLRGA+ +AL + 
Sbjct: 377 FEISFVIWCIVLVLFGRAVNIFPLSYLLNFFRDHKITPKMMFIMWFSGLRGAIPYALSLH 436

Query: 419 LDRTKVPAKDYFVATTIVVVFFTVIVQGLTIKPLVKWLKVKRSEHHK 465
           LD   +  +     TTIV+V FT+++ G +  PL++ + ++ ++ H+
Sbjct: 437 LDLEPMEKRQLIGTTTIVIVLFTILLLGGSTMPLIRLMDIEDAKAHR 483


>gi|27734935 solute carrier family 9 (sodium/hydrogen exchanger),
           member 9 [Homo sapiens]
          Length = 645

 Score =  220 bits (560), Expect = 5e-57
 Identities = 144/421 (34%), Positives = 222/421 (52%), Gaps = 20/421 (4%)

Query: 103 EPGTFFLFLLPPIVLDSGYFMPSRLFFDNLGAILTYAVVGTLWNAFTTGAALWGLQQAGL 162
           +P  FF  LLPPI+  +GY +  R FF NLG+ILTYA +GT  +    G  ++G  +A +
Sbjct: 130 DPEIFFNVLLPPIIFHAGYSLKKRHFFQNLGSILTYAFLGTAISCIVIGLIMYGFVKAMI 189

Query: 163 VAPRVQAG---LLDFLLFGSLISAVDPVAVLAVFEEVHVNETLFIIVFGESLLNDAVTVV 219
            A +++ G     D L FGSL+SA DPV VLA+F E+HV+  L+ ++FGES+LNDAV +V
Sbjct: 190 HAGQLKNGDFHFTDCLFFGSLMSATDPVTVLAIFHELHVDPDLYTLLFGESVLNDAVAIV 249

Query: 220 LYKVCNSFVEMGSANV-QATDYLKGVASLFVVSLGGAAVGLVFAFLLALTTRFTKRVR-- 276
           L    + +    + N   A  + + V +   +  G  A+G  +A + AL T+FTK     
Sbjct: 250 LTYSISIYSPKENPNAFDAAAFFQSVGNFLGIFAGSFAMGSAYAIITALLTKFTKLCEFP 309

Query: 277 IIEPLLVFLLAYAAYLTAEMASLSAILAVTMCGLGCKKYVEANISHKSRTTVKYTMKTLA 336
           ++E  L FLL+++A+L+AE A L+ I+AV  CG+    Y   N+S  S+   K   + + 
Sbjct: 310 MLETGLFFLLSWSAFLSAEAAGLTGIVAVLFCGVTQAHYTYNNLSSDSKIRTKQLFEFMN 369

Query: 337 SCAETVIFMLLGISAVDSSKWAWDSGLVLGTLIFILFFRALGVVLQTWVLNQFRLVPLDK 396
             AE VIF  +G++        +++  +LG  + I   RA  +   +++LN  R   +  
Sbjct: 370 FLAENVIFCYMGLALFTFQNHIFNALFILGAFLAIFVARACNIYPLSFLLNLGRKQKIPW 429

Query: 397 IDQVVMSYGGLRGAVAFALVILLDRTKVPAKDYFVATTIVVVFFTVIVQGLTIKPLVKWL 456
             Q +M + GLRGA+AFAL I    T+   K     TT+++VFFTV V G    P++ WL
Sbjct: 430 NFQHMMMFSGLRGAIAFALAI--RNTESQPKQMMFTTTLLLVFFTVWVFGGGTTPMLTWL 487

Query: 457 KVKRSEHHKPTL-----NQELHEHTFDHILAAVEDVVGHHGYHYWRDRWEQFDKKYLSQL 511
           +++        L     +Q    +  D  +   E          +R  W  FD KYL  +
Sbjct: 488 QIRVGVDLDENLKEDPSSQHQEANNLDKNMTKAESA------RLFR-MWYSFDHKYLKPI 540

Query: 512 L 512
           L
Sbjct: 541 L 541


>gi|14211919 solute carrier family 9, member 7 [Homo sapiens]
          Length = 725

 Score =  192 bits (487), Expect = 2e-48
 Identities = 126/379 (33%), Positives = 197/379 (51%), Gaps = 21/379 (5%)

Query: 103 EPGTFFLFLLPPIVLDSGYFMPSRLFFDNLGAILTYAVVGTLWNAFTTGAALWGLQQAGL 162
           +P  FF  LLPPI+  +GY +  R FF NLG+IL YA +GT  + F  G  ++G+ +   
Sbjct: 179 DPEVFFNILLPPIIFHAGYSLKKRHFFRNLGSILAYAFLGTAVSCFIIGNLMYGVVKLMK 238

Query: 163 VAPRVQAGLL--DFLLFGSLISAVDPVAVLAVFEEVHVNETLFIIVFGESLLNDAVTVVL 220
           +  ++       D L FG++ISA DPV VLA+F E+H +  L+ ++FGES+LNDAV +VL
Sbjct: 239 IMGQLSDKFYYTDCLFFGAIISATDPVTVLAIFNELHADVDLYALLFGESVLNDAVAIVL 298

Query: 221 YKVCNSFVEMGSANVQATD---YLKGVASLFVVSLGGAAVGLVFAFLLALTTRFTKR--V 275
                ++   G  N  A D   + K V     +  G   +G V   + A  T+FTK    
Sbjct: 299 SSSIVAYQPAG-LNTHAFDAAAFFKSVGIFLGIFSGSFTMGAVTG-VNANVTKFTKLHCF 356

Query: 276 RIIEPLLVFLLAYAAYLTAEMASLSAILAVTMCGLGCKKYVEANISHKSRTTVKYTMKTL 335
            ++E  L FL++++ +L AE    + ++AV  CG+    Y   N+S +SR+  K   + L
Sbjct: 357 PLLETALFFLMSWSTFLLAEACGFTGVVAVLFCGITQAHYTYNNLSVESRSRTKQLFEVL 416

Query: 336 ASCAETVIFMLLGISAVDSSKWAWDSGLVLGTLIFILFFRALGVVLQTWVLNQFRLVPLD 395
              AE  IF  +G++     K  +    ++G  + I   RA  +   ++ LN  R   + 
Sbjct: 417 HFLAENFIFSYMGLALFTFQKHVFSPIFIIGAFVAIFLGRAAHIYPLSFFLNLGRRHKIG 476

Query: 396 KIDQVVMSYGGLRGAVAFALVILLDRTKVPAKDYFVATTIVVVFFTVIVQGLTIKPLVKW 455
              Q +M + GLRGA+AFAL I    T   A+     TT+++VFFTV + G    P++ W
Sbjct: 477 WNFQHMMMFSGLRGAMAFALAI--RDTASYARQMMFTTTLLIVFFTVWIIGGGTTPMLSW 534

Query: 456 LKVK----------RSEHH 464
           L ++          ++EHH
Sbjct: 535 LNIRVGVEEPSEEDQNEHH 553


>gi|5454070 solute carrier family 9 (sodium/hydrogen exchanger),
           member 6 isoform b [Homo sapiens]
          Length = 669

 Score =  189 bits (481), Expect = 8e-48
 Identities = 120/350 (34%), Positives = 185/350 (52%), Gaps = 8/350 (2%)

Query: 103 EPGTFFLFLLPPIVLDSGYFMPSRLFFDNLGAILTYAVVGTLWNAFTTGAALWGLQQAGL 162
           +P  FF  LLPPI+  +GY +  R FF NLG+IL YA +GT  + F  G+ ++G      
Sbjct: 147 DPEVFFNILLPPIIFYAGYSLKRRHFFRNLGSILAYAFLGTAISCFVIGSIMYGCVTLMK 206

Query: 163 VAPRVQAGLL--DFLLFGSLISAVDPVAVLAVFEEVHVNETLFIIVFGESLLNDAVTVVL 220
           V  ++       D LLFG+++SA DPV VLA+F E+ V+  L+ ++FGES+LNDAV +VL
Sbjct: 207 VTGQLAGDFYFTDCLLFGAIVSATDPVTVLAIFHELQVDVELYALLFGESVLNDAVAIVL 266

Query: 221 YKVCNSFVEMG--SANVQATDYLKGVASLFVVSLGGAAVGLVFAFLLALTTRFTK--RVR 276
                ++   G  S     T   K +     +  G  A+G     + AL T+FTK    +
Sbjct: 267 SSSIVAYQPAGDNSHTFDVTAMFKSIGIFLGIFSGSFAMGAATGVVTALVTKFTKLREFQ 326

Query: 277 IIEPLLVFLLAYAAYLTAEMASLSAILAVTMCGLGCKKYVEANISHKSRTTVKYTMKTLA 336
           ++E  L FL++++ +L AE    + ++AV  CG+    Y   N+S +S+   K   + L 
Sbjct: 327 LLETGLFFLMSWSTFLLAEAWGFTGVVAVLFCGITQAHYTYNNLSTESQHRTKQLFELLN 386

Query: 337 SCAETVIFMLLGISAVDSSKWAWDSGLVLGTLIFILFFRALGVVLQTWVLNQFRLVPLDK 396
             AE  IF  +G++        ++   V+G  + I   RA  +   + +LN  R   +  
Sbjct: 387 FLAENFIFSYMGLTLFTFQNHVFNPTFVVGAFVAIFLGRAANIYPLSLLLNLGRRSKIGS 446

Query: 397 IDQVVMSYGGLRGAVAFALVILLDRTKVPAKDYFVATTIVVVFFTVIVQG 446
             Q +M + GLRGA+AFAL I    T   A+    +TT+++VFFTV V G
Sbjct: 447 NFQHMMMFAGLRGAMAFALAI--RDTATYARQMMFSTTLLIVFFTVWVFG 494


>gi|110227626 solute carrier family 9 (sodium/hydrogen exchanger),
           member 6 isoform a [Homo sapiens]
          Length = 701

 Score =  189 bits (481), Expect = 8e-48
 Identities = 120/350 (34%), Positives = 185/350 (52%), Gaps = 8/350 (2%)

Query: 103 EPGTFFLFLLPPIVLDSGYFMPSRLFFDNLGAILTYAVVGTLWNAFTTGAALWGLQQAGL 162
           +P  FF  LLPPI+  +GY +  R FF NLG+IL YA +GT  + F  G+ ++G      
Sbjct: 179 DPEVFFNILLPPIIFYAGYSLKRRHFFRNLGSILAYAFLGTAISCFVIGSIMYGCVTLMK 238

Query: 163 VAPRVQAGLL--DFLLFGSLISAVDPVAVLAVFEEVHVNETLFIIVFGESLLNDAVTVVL 220
           V  ++       D LLFG+++SA DPV VLA+F E+ V+  L+ ++FGES+LNDAV +VL
Sbjct: 239 VTGQLAGDFYFTDCLLFGAIVSATDPVTVLAIFHELQVDVELYALLFGESVLNDAVAIVL 298

Query: 221 YKVCNSFVEMG--SANVQATDYLKGVASLFVVSLGGAAVGLVFAFLLALTTRFTK--RVR 276
                ++   G  S     T   K +     +  G  A+G     + AL T+FTK    +
Sbjct: 299 SSSIVAYQPAGDNSHTFDVTAMFKSIGIFLGIFSGSFAMGAATGVVTALVTKFTKLREFQ 358

Query: 277 IIEPLLVFLLAYAAYLTAEMASLSAILAVTMCGLGCKKYVEANISHKSRTTVKYTMKTLA 336
           ++E  L FL++++ +L AE    + ++AV  CG+    Y   N+S +S+   K   + L 
Sbjct: 359 LLETGLFFLMSWSTFLLAEAWGFTGVVAVLFCGITQAHYTYNNLSTESQHRTKQLFELLN 418

Query: 337 SCAETVIFMLLGISAVDSSKWAWDSGLVLGTLIFILFFRALGVVLQTWVLNQFRLVPLDK 396
             AE  IF  +G++        ++   V+G  + I   RA  +   + +LN  R   +  
Sbjct: 419 FLAENFIFSYMGLTLFTFQNHVFNPTFVVGAFVAIFLGRAANIYPLSLLLNLGRRSKIGS 478

Query: 397 IDQVVMSYGGLRGAVAFALVILLDRTKVPAKDYFVATTIVVVFFTVIVQG 446
             Q +M + GLRGA+AFAL I    T   A+    +TT+++VFFTV V G
Sbjct: 479 NFQHMMMFAGLRGAMAFALAI--RDTATYARQMMFSTTLLIVFFTVWVFG 526


>gi|56786136 sperm-specific sodium proton exchanger [Homo sapiens]
          Length = 1177

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 51/249 (20%), Positives = 104/249 (41%), Gaps = 26/249 (10%)

Query: 74  VPESCLLILLGLVLGGIVLAVAKKAEYQ-----LEPGTFFLFLLPPIVLDSGYFMPSRLF 128
           +P   +L LLG     +    ++   Y      + P  FF    P +   + + M + + 
Sbjct: 41  IPVPVILFLLGCSFEVLSFTSSQVQRYANAIQWMSPDLFFRIFTPVVFFTTAFDMDTYML 100

Query: 129 FDNLGAILTYAVVGTLWNAFTTGAALWGLQQAG--LVAPRVQAGLLDFLLFGSLISAVDP 186
                 IL  ++ G L N       LW L      L+ P        +LLF +++ + DP
Sbjct: 101 QKLFWQILLISIPGFLVNYILV---LWHLASVNQLLLKPT------QWLLFSAILVSSDP 151

Query: 187 VAVLAVFEEVHVNETLFIIVFGESLLNDAVTVVLYKVCNSF---VEMGSANVQATDYLKG 243
           +   A   ++ ++ +L  ++ GESL+   ++++ +     F   ++    +  A + + G
Sbjct: 152 MLTAAAIRDLGLSRSLISLINGESLMTSVISLITFTSIMDFDQRLQSKRNHTLAEEIVGG 211

Query: 244 VASLFVVSLGGAAVGLVFAFLLA--LTTRFTKRVRIIEPLLVFLLAYAAYLTAEMASLSA 301
           + S  + S      G++ + L+   ++T F   V  I   L+F + Y  +   E+  +S 
Sbjct: 212 ICSYIIASF---LFGILSSKLIQFWMSTVFGDDVNHIS--LIFSILYLIFYICELVGMSG 266

Query: 302 ILAVTMCGL 310
           I  + + GL
Sbjct: 267 IFTLAIVGL 275


>gi|38373682 pleckstrin homology domain containing family G member 5
           isoform a [Homo sapiens]
          Length = 1006

 Score = 43.5 bits (101), Expect = 9e-04
 Identities = 53/215 (24%), Positives = 90/215 (41%), Gaps = 40/215 (18%)

Query: 701 ESEEEEEESDSSETEKEDDEGIIFVARATSEVLQEGKVSGSLEVCPSPR--------IIP 752
           E E+E+EE +  E E+E+ E     A ++  ++++   S   + C S          ++ 
Sbjct: 706 EEEDEQEEEEEEEEEEEEGEDSGTSAASSPTIMRKSSGSPDSQHCASDGSTETLAMVVVE 765

Query: 753 PSPTCAEKEL---PWKSGQGDLAVYVSSE----TTKIVPVDMQTGWNQSISSLESLASPP 805
           P  T +  E    P+ S   + ++  ++     T++++P+    G + S+ S     SP 
Sbjct: 766 PGDTLSSPEFDSGPFSSQSDETSLSTTASSATPTSELLPLGPVDGRSCSMDSAYGTLSPT 825

Query: 806 CNQ-----APILTCLPPHPRGTEEPQVPLHLPS------DPRSSFAFPPSLAKAGRSRSE 854
             Q      P+   +   PR  E P+VP   PS       P    + PP L K   S+SE
Sbjct: 826 SLQDFVAPGPMAELV---PRAPESPRVPSPPPSPRLRRRTPVQLLSCPPHLLK---SKSE 879

Query: 855 SSADLPQQQELQPLMGHKDH-THLSPGTATSHWCI 888
           +S        LQ L G   H T  +P  + S  C+
Sbjct: 880 ASL-------LQLLAGAGTHGTPSAPSRSLSELCL 907


>gi|111154084 pleckstrin homology domain containing family G member
           5 isoform b [Homo sapiens]
          Length = 1083

 Score = 43.5 bits (101), Expect = 9e-04
 Identities = 53/215 (24%), Positives = 90/215 (41%), Gaps = 40/215 (18%)

Query: 701 ESEEEEEESDSSETEKEDDEGIIFVARATSEVLQEGKVSGSLEVCPSPR--------IIP 752
           E E+E+EE +  E E+E+ E     A ++  ++++   S   + C S          ++ 
Sbjct: 783 EEEDEQEEEEEEEEEEEEGEDSGTSAASSPTIMRKSSGSPDSQHCASDGSTETLAMVVVE 842

Query: 753 PSPTCAEKEL---PWKSGQGDLAVYVSSE----TTKIVPVDMQTGWNQSISSLESLASPP 805
           P  T +  E    P+ S   + ++  ++     T++++P+    G + S+ S     SP 
Sbjct: 843 PGDTLSSPEFDSGPFSSQSDETSLSTTASSATPTSELLPLGPVDGRSCSMDSAYGTLSPT 902

Query: 806 CNQ-----APILTCLPPHPRGTEEPQVPLHLPS------DPRSSFAFPPSLAKAGRSRSE 854
             Q      P+   +   PR  E P+VP   PS       P    + PP L K   S+SE
Sbjct: 903 SLQDFVAPGPMAELV---PRAPESPRVPSPPPSPRLRRRTPVQLLSCPPHLLK---SKSE 956

Query: 855 SSADLPQQQELQPLMGHKDH-THLSPGTATSHWCI 888
           +S        LQ L G   H T  +P  + S  C+
Sbjct: 957 ASL-------LQLLAGAGTHGTPSAPSRSLSELCL 984


>gi|111154088 pleckstrin homology domain containing family G member
           5 isoform a [Homo sapiens]
          Length = 1006

 Score = 43.5 bits (101), Expect = 9e-04
 Identities = 53/215 (24%), Positives = 90/215 (41%), Gaps = 40/215 (18%)

Query: 701 ESEEEEEESDSSETEKEDDEGIIFVARATSEVLQEGKVSGSLEVCPSPR--------IIP 752
           E E+E+EE +  E E+E+ E     A ++  ++++   S   + C S          ++ 
Sbjct: 706 EEEDEQEEEEEEEEEEEEGEDSGTSAASSPTIMRKSSGSPDSQHCASDGSTETLAMVVVE 765

Query: 753 PSPTCAEKEL---PWKSGQGDLAVYVSSE----TTKIVPVDMQTGWNQSISSLESLASPP 805
           P  T +  E    P+ S   + ++  ++     T++++P+    G + S+ S     SP 
Sbjct: 766 PGDTLSSPEFDSGPFSSQSDETSLSTTASSATPTSELLPLGPVDGRSCSMDSAYGTLSPT 825

Query: 806 CNQ-----APILTCLPPHPRGTEEPQVPLHLPS------DPRSSFAFPPSLAKAGRSRSE 854
             Q      P+   +   PR  E P+VP   PS       P    + PP L K   S+SE
Sbjct: 826 SLQDFVAPGPMAELV---PRAPESPRVPSPPPSPRLRRRTPVQLLSCPPHLLK---SKSE 879

Query: 855 SSADLPQQQELQPLMGHKDH-THLSPGTATSHWCI 888
           +S        LQ L G   H T  +P  + S  C+
Sbjct: 880 ASL-------LQLLAGAGTHGTPSAPSRSLSELCL 907


>gi|111154080 pleckstrin homology domain containing family G member
           5 isoform a [Homo sapiens]
          Length = 1006

 Score = 43.5 bits (101), Expect = 9e-04
 Identities = 53/215 (24%), Positives = 90/215 (41%), Gaps = 40/215 (18%)

Query: 701 ESEEEEEESDSSETEKEDDEGIIFVARATSEVLQEGKVSGSLEVCPSPR--------IIP 752
           E E+E+EE +  E E+E+ E     A ++  ++++   S   + C S          ++ 
Sbjct: 706 EEEDEQEEEEEEEEEEEEGEDSGTSAASSPTIMRKSSGSPDSQHCASDGSTETLAMVVVE 765

Query: 753 PSPTCAEKEL---PWKSGQGDLAVYVSSE----TTKIVPVDMQTGWNQSISSLESLASPP 805
           P  T +  E    P+ S   + ++  ++     T++++P+    G + S+ S     SP 
Sbjct: 766 PGDTLSSPEFDSGPFSSQSDETSLSTTASSATPTSELLPLGPVDGRSCSMDSAYGTLSPT 825

Query: 806 CNQ-----APILTCLPPHPRGTEEPQVPLHLPS------DPRSSFAFPPSLAKAGRSRSE 854
             Q      P+   +   PR  E P+VP   PS       P    + PP L K   S+SE
Sbjct: 826 SLQDFVAPGPMAELV---PRAPESPRVPSPPPSPRLRRRTPVQLLSCPPHLLK---SKSE 879

Query: 855 SSADLPQQQELQPLMGHKDH-THLSPGTATSHWCI 888
           +S        LQ L G   H T  +P  + S  C+
Sbjct: 880 ASL-------LQLLAGAGTHGTPSAPSRSLSELCL 907


>gi|111154078 pleckstrin homology domain containing family G member
           5 isoform c [Homo sapiens]
          Length = 1062

 Score = 43.5 bits (101), Expect = 9e-04
 Identities = 53/215 (24%), Positives = 90/215 (41%), Gaps = 40/215 (18%)

Query: 701 ESEEEEEESDSSETEKEDDEGIIFVARATSEVLQEGKVSGSLEVCPSPR--------IIP 752
           E E+E+EE +  E E+E+ E     A ++  ++++   S   + C S          ++ 
Sbjct: 762 EEEDEQEEEEEEEEEEEEGEDSGTSAASSPTIMRKSSGSPDSQHCASDGSTETLAMVVVE 821

Query: 753 PSPTCAEKEL---PWKSGQGDLAVYVSSE----TTKIVPVDMQTGWNQSISSLESLASPP 805
           P  T +  E    P+ S   + ++  ++     T++++P+    G + S+ S     SP 
Sbjct: 822 PGDTLSSPEFDSGPFSSQSDETSLSTTASSATPTSELLPLGPVDGRSCSMDSAYGTLSPT 881

Query: 806 CNQ-----APILTCLPPHPRGTEEPQVPLHLPS------DPRSSFAFPPSLAKAGRSRSE 854
             Q      P+   +   PR  E P+VP   PS       P    + PP L K   S+SE
Sbjct: 882 SLQDFVAPGPMAELV---PRAPESPRVPSPPPSPRLRRRTPVQLLSCPPHLLK---SKSE 935

Query: 855 SSADLPQQQELQPLMGHKDH-THLSPGTATSHWCI 888
           +S        LQ L G   H T  +P  + S  C+
Sbjct: 936 ASL-------LQLLAGAGTHGTPSAPSRSLSELCL 963


>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
          Length = 953

 Score = 39.7 bits (91), Expect = 0.013
 Identities = 51/205 (24%), Positives = 85/205 (41%), Gaps = 24/205 (11%)

Query: 570 NLLRESGSGACLD--------LQVIDTVRSGRDREDAVMHHLLCGGLYKPRRRYKAS--- 618
           ++LR+SGS   LD        L+  ++   G  +E+   H        +P+ + + S   
Sbjct: 27  DILRDSGSDQDLDGAGVRASDLEDEESAARGPSQEEEDNHSDEEDRASEPKSQDQDSEVN 86

Query: 619 -CSRHFISEDAQERQDKEVFQQNMKRRLESFKSTK----HNICFTKSKPR-PRKTGRRKK 672
             SR   S   +E  D+    +    R E+   T+    H + + +  P  P    +  +
Sbjct: 87  ELSRGPTSSPCEEEGDEGEEDRTSDLRDEASSVTRELDEHELDYDEEVPEEPAPAVQEDE 146

Query: 673 DGVANAEATNGKHRGLGFQDTAAVILTVESEEEEEESDSSETEKEDDEGIIFVARATSEV 732
              A AE    K  G   ++  A + +V  +E  E +   E +KEDD+G I       + 
Sbjct: 147 AEKAGAEDDEEKGEGTPREEGKAGVQSVGEKESLEAA--KEKKKEDDDGEIDDGEIDDDD 204

Query: 733 LQEGKVSGSLEVCPSPRIIPPSPTC 757
           L+EG+V       PS R + P PTC
Sbjct: 205 LEEGEVKD-----PSDRKVRPRPTC 224


>gi|45359846 Ras-GTPase activating protein SH3 domain-binding
           protein 2 isoform b [Homo sapiens]
          Length = 449

 Score = 37.0 bits (84), Expect = 0.082
 Identities = 41/161 (25%), Positives = 66/161 (40%), Gaps = 21/161 (13%)

Query: 701 ESEEEEEESDSSETEKEDDEGIIFVARATSEVLQEGKVSGSLEVCPSPRIIPPSPTCAEK 760
           +SE E +E    E E+E +E      + + E +QE   SG  E  P    I       E+
Sbjct: 140 DSEPELDEESEDEVEEEQEE-----RQPSPEPVQENANSGYYEAHPVTNGI-------EE 187

Query: 761 ELPWKSGQGDLAVYVSSETTKIVPVDMQTGWNQSISSLESLASPPCNQAPI-LTCLPPHP 819
            L   S + +      ++T ++ P   +    +++  LE  ++ P    P+ L   PP P
Sbjct: 188 PLEESSHEPEPEPESETKTEELKPQVEE----KNLEELEEKSTTPPPAEPVSLPQEPPKP 243

Query: 820 RGTEEPQVPLHLP----SDPRSSFAFPPSLAKAGRSRSESS 856
           R   +P+V    P      PR    FPP   + GR   E +
Sbjct: 244 RVEAKPEVQSQPPRVREQRPRERPGFPPRGPRPGRGDMEQN 284


>gi|28274705 family with sequence similarity 9, member A [Homo
           sapiens]
          Length = 332

 Score = 37.0 bits (84), Expect = 0.082
 Identities = 27/102 (26%), Positives = 46/102 (45%), Gaps = 8/102 (7%)

Query: 626 EDAQERQDKEVFQQNMKRRLESFKSTKHNICFTKSKPRPRK---TGRRKKDGVANAEATN 682
           + A  R+ K   ++ +K++    K  K +   T+      K     ++K D    AEA  
Sbjct: 141 DKAAYRKTKNTIERALKKK--QLKRQKRDYRHTRKLLNVLKEYIAEKQKDDEAEEAEAAA 198

Query: 683 GKHRGLGFQDTAAV---ILTVESEEEEEESDSSETEKEDDEG 721
                    + AA    ++ VE EEEEE+ +  E E+E++EG
Sbjct: 199 AAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEG 240


>gi|4757816 ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
           isoform 1 [Homo sapiens]
          Length = 205

 Score = 37.0 bits (84), Expect = 0.082
 Identities = 45/184 (24%), Positives = 76/184 (41%), Gaps = 32/184 (17%)

Query: 108 FLFLLPPIVLDSGYFMPSRLFFDNLGAILTYAVVGTLWNAFTTGAALWGLQQAGLVAPRV 167
           F F +   + ++  FM S L    +G  ++ +VVG  W  + TG+++ G    G+ APR+
Sbjct: 33  FRFDVAWFLTETSPFMWSNL---GIGLAISLSVVGAAWGIYITGSSIIG---GGVKAPRI 86

Query: 168 QAGLLDFLLFGSLI------------------SAVDPVAVLAVFEEVHVNETLFIIVFGE 209
           +   L  ++F   +                  SA DP A+       H N      +FG 
Sbjct: 87  KTKNLVSIIFCEAVAIYGIIMAIVISNMAEPFSATDPKAI------GHRNYHAGYSMFGA 140

Query: 210 SLLNDAVTVVLYKVCNSFVEMGSANVQATDYLKGVASLFVVSLGGAAVGLVFAFLLALTT 269
             L   ++ +   VC   V  G+A   A +    V  + +V + G+A+GL    +  L T
Sbjct: 141 G-LTVGLSNLFCGVCVGIVGSGAALADAQNPSLFV-KILIVEIFGSAIGLFGVIVAILQT 198

Query: 270 RFTK 273
              K
Sbjct: 199 SRVK 202


>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
          Length = 1462

 Score = 36.6 bits (83), Expect = 0.11
 Identities = 52/254 (20%), Positives = 96/254 (37%), Gaps = 34/254 (13%)

Query: 613 RRYKASCSR-----------HFISEDAQERQDKEVFQQNMKRRLESFKSTKHNICFTKSK 661
           RR K+SC R           H  S+    + DK+V         +S++S  H+  +++  
Sbjct: 473 RRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYSRGS 532

Query: 662 PRPRKTGRRKKDGVANAEATNGKHRGLGFQDTAAVILTVESEEEEEESDSSETEKEDDEG 721
            R R   +      + +++ +    G   +              +  S  SE +    E 
Sbjct: 533 SRSRTASKSSSHSRSRSKSRSSSKSGHRKR--------ASKSPRKTASQLSENKPVKTEP 584

Query: 722 IIFVARATSEVLQEGKVSGSLEVCPSPRIIPPSPTCAEKELPWKSGQGDLAVYVSSETTK 781
           +         V+ +  V+ ++ V P     PPS      + PWK    +    + ++TT 
Sbjct: 585 LRATMAQNENVVVQPVVAENIPVIPLSDSPPPS-RWKPGQKPWKPSY-ERIQEMKAKTTH 642

Query: 782 IVPVDMQTGWNQSISSLESLASPPCNQAPILTCLPPHPRGTEEPQVPLHLPSDPRSSFAF 841
           ++P+       QS  SL ++     + +          + +E  Q      SD RSS + 
Sbjct: 643 LLPI-------QSTYSLANIKETGSSSS-----YHKREKNSESDQSTYSKYSD-RSSESS 689

Query: 842 PPSLAKAGRSRSES 855
           P S +++ RSRS S
Sbjct: 690 PRSRSRSSRSRSYS 703


>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
           containing B [Homo sapiens]
          Length = 546

 Score = 36.2 bits (82), Expect = 0.14
 Identities = 29/117 (24%), Positives = 47/117 (40%), Gaps = 6/117 (5%)

Query: 601 HHLLCGGLYKPRRRYKASCSRHFISEDAQERQDKEVFQQNMKRRLESFKSTKHNICFTKS 660
           HH    G     R  +    R  +  +A+ER+ +    +++ R LE  +S       ++S
Sbjct: 281 HHREGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRS 340

Query: 661 KPRPRKTGRRKKDGVANAEATNGKHRGLGFQDTAAVILTVESEEEEEESDSSETEKE 717
           + R RK  RR +D     E   G+ R   +           +E E+E   S E  KE
Sbjct: 341 RSRDRKGDRRDRDREREKENERGRRRDRDYDKERG------NEREKERERSRERSKE 391


>gi|209862789 microtubule associated monoxygenase, calponin and LIM
            domain containing 3 isoform 1 [Homo sapiens]
          Length = 2002

 Score = 36.2 bits (82), Expect = 0.14
 Identities = 81/380 (21%), Positives = 145/380 (38%), Gaps = 61/380 (16%)

Query: 529  YRLNIRDAISFVD-----QGGHVLSSTGLTLPSMPSRNSVAETSVTNLLRESGSGACLDL 583
            YRL++R A +  +     Q  H LSS   T     +   VA +S  + + E G     + 
Sbjct: 896  YRLSLRQAEALQEVPEETQAEHNLSSVLDT----GAEEDVASSSSESEMEEEGEEEEEEP 951

Query: 584  QVIDTVRSGRDREDAVMHHLLCGGLYKPRRRYKASCSRHFISEDAQERQDKEVFQQNMKR 643
            ++  +   G   ++AV  H L  G    +   +   S+ F   + +E +++E +++  + 
Sbjct: 952  RLPPSDLGGVPWKEAVRIHALLKG----KSEEELEASKSFGPGNEEEEEEEEEYEEEEEE 1007

Query: 644  RLESFKSTKHNICFTKSKPRPRKTGRRKKDGVANAEATNGKHRGLGFQDTAAVILTVESE 703
                         + + +    + G ++   V +A            +  A V  T   E
Sbjct: 1008 D------------YDEEEEESSEAGNQRLQQVMHAADP--------LEIQADVHWTHIRE 1047

Query: 704  EEEEE-----SDSSETEKEDDEGIIFV------ARATSEVLQEGKVSGSLEVCPSPRIIP 752
             EEEE     S+SS +    DE  +        A    E  ++G    +       +   
Sbjct: 1048 REEEERMAPASESSASGAPLDENDLEEDVDSEPAEIEGEAAEDGDPGDTGAELDDDQHWS 1107

Query: 753  PSPTCAEKELPWK---SGQGDLAVYVSSETTKIV--PVDMQTGWNQSISSLESLASPPCN 807
             SP+ A++EL       G+ +L + VS +  K+   P   + G +Q+ S + S       
Sbjct: 1108 DSPSDADRELRLPCPAEGEAELELRVSEDEEKLPASPKHQERGPSQATSPIRS------P 1161

Query: 808  QAPILTCLPPHPRGTEEPQ---VPLHLPSDPRSSFAFPPSLAKAGRSRSESSADLPQQQ- 863
            Q   L  +P H   TE PQ   VP            FP  L    + ++++ +DL     
Sbjct: 1162 QESALLFIPVHSPSTEGPQLPPVPAATQEKSPEERLFPEPLLPKEKPKADAPSDLKAVHS 1221

Query: 864  --ELQPLMGHKDHTHLSPGT 881
                QP+   +  T +SPG+
Sbjct: 1222 PIRSQPVTLPEARTPVSPGS 1241


>gi|119964726 insulin-like growth factor 2 receptor precursor [Homo
           sapiens]
          Length = 2491

 Score = 35.8 bits (81), Expect = 0.18
 Identities = 32/98 (32%), Positives = 44/98 (44%), Gaps = 20/98 (20%)

Query: 680 ATNGKHRGLGFQDTAAVILTVESEEEEEESDSSETEKEDDEGIIFVARATSEVLQEGKVS 739
           AT+GK R     D +A++   E E+  E  D S+TE E     I +      VLQEGK  
Sbjct: 477 ATDGKKR----YDLSALVRHAEPEQNWEAVDGSQTETEKKHFFINICH---RVLQEGKAR 529

Query: 740 GSLEVCPSPRIIPPSPTCAEKELPWKSGQGDLAVYVSS 777
           G    CP    +     CA      K+G  +L  ++SS
Sbjct: 530 G----CPEDAAV-----CAVD----KNGSKNLGKFISS 554


>gi|86792634 ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
           isoform 2 [Homo sapiens]
          Length = 158

 Score = 35.8 bits (81), Expect = 0.18
 Identities = 39/160 (24%), Positives = 66/160 (41%), Gaps = 29/160 (18%)

Query: 132 LGAILTYAVVGTLWNAFTTGAALWGLQQAGLVAPRVQAGLLDFLLFGSLI---------- 181
           +G  ++ +VVG  W  + TG+++ G    G+ APR++   L  ++F   +          
Sbjct: 7   IGLAISLSVVGAAWGIYITGSSIIG---GGVKAPRIKTKNLVSIIFCEAVAIYGIIMAIV 63

Query: 182 --------SAVDPVAVLAVFEEVHVNETLFIIVFGESLLNDAVTVVLYKVCNSFVEMGSA 233
                   SA DP A+       H N      +FG   L   ++ +   VC   V  G+A
Sbjct: 64  ISNMAEPFSATDPKAI------GHRNYHAGYSMFGAG-LTVGLSNLFCGVCVGIVGSGAA 116

Query: 234 NVQATDYLKGVASLFVVSLGGAAVGLVFAFLLALTTRFTK 273
              A +    V  + +V + G+A+GL    +  L T   K
Sbjct: 117 LADAQNPSLFV-KILIVEIFGSAIGLFGVIVAILQTSRVK 155


>gi|157384971 cyclin G associated kinase [Homo sapiens]
          Length = 1311

 Score = 35.4 bits (80), Expect = 0.24
 Identities = 62/270 (22%), Positives = 94/270 (34%), Gaps = 33/270 (12%)

Query: 645  LESFKSTKHNICFTKSKPR-PRKTGRRKK----DGVANAEATNGKHRGLGFQDTAAVILT 699
            L S +  + +I     KP  PR+ G   +     G   AE T+         D +  + T
Sbjct: 735  LFSSREEQQDILSKFGKPELPRQPGSTAQYDAGAGSPEAEPTDSDSPPSSSADASRFLHT 794

Query: 700  VESEEEEE-ESDSSETEKEDDEGIIFVARATSEVLQEGKVSGSLEVCPSPRIIPPSPTCA 758
            ++ +EE+E E+ +     ++ E  +   R  SEV  EG    S E    PR  P  P  A
Sbjct: 795  LDWQEEKEAETGAENASSKESESALMEDRDESEVSDEGGSPISSE-GQEPRADPEPPGLA 853

Query: 759  ------------------EKELPWKSGQGDLAVYVSSETTKIVPVDMQTGWNQSISSLES 800
                               + +P + G   L ++        VP       + +   L  
Sbjct: 854  AGLVQQDLVFEVETPAVLPEPVPQEDGVDLLGLHSEVGAGPAVPPQACKAPSSNTDLLSC 913

Query: 801  LASPP--CNQAPILTCLPPHPRGTEEPQVPLHLPSDPRSSFAFPPSLAKAGRSRSESSAD 858
            L  PP   +Q P    L   P     P  PL + S PR     PP+ A        SS +
Sbjct: 914  LLGPPEAASQGPPEDLLSEDPLLLASPAPPLSVQSTPRGG---PPAAADPFGPLLPSSGN 970

Query: 859  LPQQQELQPLMG---HKDHTHLSPGTATSH 885
              Q      L G   + D   + P   ++H
Sbjct: 971  NSQPCSNPDLFGEFLNSDSVTVPPSFPSAH 1000


>gi|183396783 BCL-6 interacting corepressor isoform a [Homo sapiens]
          Length = 1721

 Score = 35.4 bits (80), Expect = 0.24
 Identities = 26/85 (30%), Positives = 36/85 (42%), Gaps = 11/85 (12%)

Query: 751 IPPSPTCAEKELPWKSGQGDLAVYVSSETTKIVPVDMQTGWNQSISSLESLASPPCNQAP 810
           IPP   CA+K LPWK G     V   +         +Q      + S +++ S       
Sbjct: 276 IPPLVHCADKSLPWKMG-----VSPGNPVDSHAYPHIQNSKQPRVPSAKAVTSGLPGDTA 330

Query: 811 ILTCLPPHPRGTEEPQVPLHLPSDP 835
           +L  LPP PR    P   +HLP+ P
Sbjct: 331 LL--LPPSPR----PSPRVHLPTQP 349


>gi|183396787 BCL-6 interacting corepressor isoform c [Homo sapiens]
          Length = 1755

 Score = 35.4 bits (80), Expect = 0.24
 Identities = 26/85 (30%), Positives = 36/85 (42%), Gaps = 11/85 (12%)

Query: 751 IPPSPTCAEKELPWKSGQGDLAVYVSSETTKIVPVDMQTGWNQSISSLESLASPPCNQAP 810
           IPP   CA+K LPWK G     V   +         +Q      + S +++ S       
Sbjct: 276 IPPLVHCADKSLPWKMG-----VSPGNPVDSHAYPHIQNSKQPRVPSAKAVTSGLPGDTA 330

Query: 811 ILTCLPPHPRGTEEPQVPLHLPSDP 835
           +L  LPP PR    P   +HLP+ P
Sbjct: 331 LL--LPPSPR----PSPRVHLPTQP 349


>gi|183396785 BCL-6 interacting corepressor isoform b [Homo sapiens]
          Length = 1703

 Score = 35.4 bits (80), Expect = 0.24
 Identities = 26/85 (30%), Positives = 36/85 (42%), Gaps = 11/85 (12%)

Query: 751 IPPSPTCAEKELPWKSGQGDLAVYVSSETTKIVPVDMQTGWNQSISSLESLASPPCNQAP 810
           IPP   CA+K LPWK G     V   +         +Q      + S +++ S       
Sbjct: 276 IPPLVHCADKSLPWKMG-----VSPGNPVDSHAYPHIQNSKQPRVPSAKAVTSGLPGDTA 330

Query: 811 ILTCLPPHPRGTEEPQVPLHLPSDP 835
           +L  LPP PR    P   +HLP+ P
Sbjct: 331 LL--LPPSPR----PSPRVHLPTQP 349


>gi|21071037 BCL-6 interacting corepressor isoform a [Homo sapiens]
          Length = 1721

 Score = 35.4 bits (80), Expect = 0.24
 Identities = 26/85 (30%), Positives = 36/85 (42%), Gaps = 11/85 (12%)

Query: 751 IPPSPTCAEKELPWKSGQGDLAVYVSSETTKIVPVDMQTGWNQSISSLESLASPPCNQAP 810
           IPP   CA+K LPWK G     V   +         +Q      + S +++ S       
Sbjct: 276 IPPLVHCADKSLPWKMG-----VSPGNPVDSHAYPHIQNSKQPRVPSAKAVTSGLPGDTA 330

Query: 811 ILTCLPPHPRGTEEPQVPLHLPSDP 835
           +L  LPP PR    P   +HLP+ P
Sbjct: 331 LL--LPPSPR----PSPRVHLPTQP 349


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.406 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,921,176
Number of Sequences: 37866
Number of extensions: 1554962
Number of successful extensions: 11891
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 133
Number of HSP's that attempted gapping in prelim test: 10951
Number of HSP's gapped (non-prelim): 714
length of query: 896
length of database: 18,247,518
effective HSP length: 111
effective length of query: 785
effective length of database: 14,044,392
effective search space: 11024847720
effective search space used: 11024847720
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press