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Search of human proteins with 4758804
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4758804 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 3 isoform 2 [Homo sapiens]
(1068 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4758804 nuclear factor of activated T-cells, cytoplasmic, cal... 2212 0.0
gi|27886559 nuclear factor of activated T-cells, cytoplasmic, ca... 2148 0.0
gi|27886555 nuclear factor of activated T-cells, cytoplasmic, ca... 2145 0.0
gi|27886561 nuclear factor of activated T-cells, cytoplasmic, ca... 2139 0.0
gi|209862845 nuclear factor of activated T-cells, cytoplasmic, c... 591 e-168
gi|27886563 nuclear factor of activated T-cells, cytoplasmic, ca... 591 e-168
gi|19923350 nuclear factor of activated T-cells, cytosolic compo... 561 e-159
gi|27502386 nuclear factor of activated T-cells, cytosolic compo... 559 e-159
gi|27502391 nuclear factor of activated T-cells, cytosolic compo... 559 e-159
gi|27502393 nuclear factor of activated T-cells, cytosolic compo... 558 e-159
gi|27886539 nuclear factor of activated T-cells, cytoplasmic, ca... 453 e-127
gi|27886541 nuclear factor of activated T-cells, cytoplasmic, ca... 453 e-127
gi|209862843 nuclear factor of activated T-cells, cytoplasmic, c... 451 e-126
gi|27502388 nuclear factor of activated T-cells, cytosolic compo... 324 2e-88
gi|5729945 nuclear factor of activated T-cells 5 isoform c [Homo... 226 1e-58
gi|27886520 nuclear factor of activated T-cells 5 isoform a [Hom... 225 2e-58
gi|164419744 nuclear factor of activated T-cells 5 isoform b [Ho... 225 2e-58
gi|27886524 nuclear factor of activated T-cells 5 isoform a [Hom... 225 2e-58
gi|164419746 nuclear factor of activated T-cells 5 isoform d [Ho... 223 7e-58
gi|223468681 v-rel reticuloendotheliosis viral oncogene homolog ... 62 4e-09
gi|223468676 v-rel reticuloendotheliosis viral oncogene homolog ... 61 6e-09
gi|167736355 mucin 4 isoform a [Homo sapiens] 55 4e-07
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 54 6e-07
gi|91982772 mucin 17 [Homo sapiens] 54 6e-07
gi|112382214 SEC24 (S. cerevisiae) homolog B isoform b [Homo sap... 52 2e-06
gi|58530876 melanoma antigen family C, 1 [Homo sapiens] 46 2e-04
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens] 45 3e-04
gi|28558973 mediator complex subunit 14 [Homo sapiens] 45 3e-04
gi|119943102 CREB binding protein isoform b [Homo sapiens] 45 4e-04
gi|119943104 CREB binding protein isoform a [Homo sapiens] 45 4e-04
>gi|4758804 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 3 isoform 2 [Homo sapiens]
Length = 1068
Score = 2212 bits (5732), Expect = 0.0
Identities = 1068/1068 (100%), Positives = 1068/1068 (100%)
Query: 1 MTTANCGAHDELDFKLVFGEDGAPAPPPPGSRPADLEPDDCASIYIFNVDPPPSTLTTPL 60
MTTANCGAHDELDFKLVFGEDGAPAPPPPGSRPADLEPDDCASIYIFNVDPPPSTLTTPL
Sbjct: 1 MTTANCGAHDELDFKLVFGEDGAPAPPPPGSRPADLEPDDCASIYIFNVDPPPSTLTTPL 60
Query: 61 CLPHHGLPSHSSVLSPSFQLQSHKNYEGTCEIPESKYSPLGGPKPFECPSIQITSISPNC 120
CLPHHGLPSHSSVLSPSFQLQSHKNYEGTCEIPESKYSPLGGPKPFECPSIQITSISPNC
Sbjct: 61 CLPHHGLPSHSSVLSPSFQLQSHKNYEGTCEIPESKYSPLGGPKPFECPSIQITSISPNC 120
Query: 121 HQELDAHEDDLQINDPEREFLERPSRDHLYLPLEPSYRESSLSPSPASSISSRSWFSDAS 180
HQELDAHEDDLQINDPEREFLERPSRDHLYLPLEPSYRESSLSPSPASSISSRSWFSDAS
Sbjct: 121 HQELDAHEDDLQINDPEREFLERPSRDHLYLPLEPSYRESSLSPSPASSISSRSWFSDAS 180
Query: 181 SCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCPGEETWHQQYGLGHSLSPRQS 240
SCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCPGEETWHQQYGLGHSLSPRQS
Sbjct: 181 SCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCPGEETWHQQYGLGHSLSPRQS 240
Query: 241 PCHSPRSSVTDENWLSPRPASGPSSRPTSPCGKRRHSSAEVCYAGSLSPHHSPVPSPGHS 300
PCHSPRSSVTDENWLSPRPASGPSSRPTSPCGKRRHSSAEVCYAGSLSPHHSPVPSPGHS
Sbjct: 241 PCHSPRSSVTDENWLSPRPASGPSSRPTSPCGKRRHSSAEVCYAGSLSPHHSPVPSPGHS 300
Query: 301 PRGSVTEDTWLNASVHGGSGLGPAVFPFQYCVETDIPLKTRKTSEDQAAILPGKLELCSD 360
PRGSVTEDTWLNASVHGGSGLGPAVFPFQYCVETDIPLKTRKTSEDQAAILPGKLELCSD
Sbjct: 301 PRGSVTEDTWLNASVHGGSGLGPAVFPFQYCVETDIPLKTRKTSEDQAAILPGKLELCSD 360
Query: 361 DQGSLSPARETSIDDGLGSQYPLKKDSCGDQFLSVPSPFTWSKPKPGHTPIFRTSSLPPL 420
DQGSLSPARETSIDDGLGSQYPLKKDSCGDQFLSVPSPFTWSKPKPGHTPIFRTSSLPPL
Sbjct: 361 DQGSLSPARETSIDDGLGSQYPLKKDSCGDQFLSVPSPFTWSKPKPGHTPIFRTSSLPPL 420
Query: 421 DWPLPAHFGQCELKIEVQPKTHHRAHYETEGSRGAVKASTGGHPVVKLLGYNEKPINLQM 480
DWPLPAHFGQCELKIEVQPKTHHRAHYETEGSRGAVKASTGGHPVVKLLGYNEKPINLQM
Sbjct: 421 DWPLPAHFGQCELKIEVQPKTHHRAHYETEGSRGAVKASTGGHPVVKLLGYNEKPINLQM 480
Query: 481 FIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLLPENNMSASIDCAGI 540
FIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLLPENNMSASIDCAGI
Sbjct: 481 FIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLLPENNMSASIDCAGI 540
Query: 541 LKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELP 600
LKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELP
Sbjct: 541 LKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELP 600
Query: 601 HIEKYSINSCSVNGGHEMVVTGSNFLPESKIIFLEKGQDGRPQWEVEGKIIREKCQGAHI 660
HIEKYSINSCSVNGGHEMVVTGSNFLPESKIIFLEKGQDGRPQWEVEGKIIREKCQGAHI
Sbjct: 601 HIEKYSINSCSVNGGHEMVVTGSNFLPESKIIFLEKGQDGRPQWEVEGKIIREKCQGAHI 660
Query: 661 VLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTPVLMKQEHREEIDLSSVPSLPV 720
VLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTPVLMKQEHREEIDLSSVPSLPV
Sbjct: 661 VLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTPVLMKQEHREEIDLSSVPSLPV 720
Query: 721 PHPAQTQRPSSDSGCSHDSVLSGQRSLICSIPQTYASMVTSSHLPQLQCRDESVSKEQHM 780
PHPAQTQRPSSDSGCSHDSVLSGQRSLICSIPQTYASMVTSSHLPQLQCRDESVSKEQHM
Sbjct: 721 PHPAQTQRPSSDSGCSHDSVLSGQRSLICSIPQTYASMVTSSHLPQLQCRDESVSKEQHM 780
Query: 781 IPSPIVHQPFQVTPTPPVGSSYQPMQTNVVYNGPTCLPINAASSQEFDSVLFQQDATLSG 840
IPSPIVHQPFQVTPTPPVGSSYQPMQTNVVYNGPTCLPINAASSQEFDSVLFQQDATLSG
Sbjct: 781 IPSPIVHQPFQVTPTPPVGSSYQPMQTNVVYNGPTCLPINAASSQEFDSVLFQQDATLSG 840
Query: 841 LVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHSVHTLPHLQSMGYHCSNTGQRSLSSPVAD 900
LVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHSVHTLPHLQSMGYHCSNTGQRSLSSPVAD
Sbjct: 841 LVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHSVHTLPHLQSMGYHCSNTGQRSLSSPVAD 900
Query: 901 QITGQPSSQLQPITYGPSHSGSATTASPAASHPLASSPLSGPPSPQLQPMPYQSPSSGTA 960
QITGQPSSQLQPITYGPSHSGSATTASPAASHPLASSPLSGPPSPQLQPMPYQSPSSGTA
Sbjct: 901 QITGQPSSQLQPITYGPSHSGSATTASPAASHPLASSPLSGPPSPQLQPMPYQSPSSGTA 960
Query: 961 SSPSPATRMHSGQHSTQAQSTGQGGLSAPSSLICHSLCDPASFPPDGATVSIKPEPEDRE 1020
SSPSPATRMHSGQHSTQAQSTGQGGLSAPSSLICHSLCDPASFPPDGATVSIKPEPEDRE
Sbjct: 961 SSPSPATRMHSGQHSTQAQSTGQGGLSAPSSLICHSLCDPASFPPDGATVSIKPEPEDRE 1020
Query: 1021 PNFATIGLQDITLDDDQFISDLEHQPSGSAEKWPNHSVLSCPAPFWRI 1068
PNFATIGLQDITLDDDQFISDLEHQPSGSAEKWPNHSVLSCPAPFWRI
Sbjct: 1021 PNFATIGLQDITLDDDQFISDLEHQPSGSAEKWPNHSVLSCPAPFWRI 1068
>gi|27886559 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 3 isoform 4 [Homo sapiens]
Length = 1045
Score = 2148 bits (5565), Expect = 0.0
Identities = 1039/1042 (99%), Positives = 1041/1042 (99%)
Query: 1 MTTANCGAHDELDFKLVFGEDGAPAPPPPGSRPADLEPDDCASIYIFNVDPPPSTLTTPL 60
MTTANCGAHDELDFKLVFGEDGAPAPPPPGSRPADLEPDDCASIYIFNVDPPPSTLTTPL
Sbjct: 1 MTTANCGAHDELDFKLVFGEDGAPAPPPPGSRPADLEPDDCASIYIFNVDPPPSTLTTPL 60
Query: 61 CLPHHGLPSHSSVLSPSFQLQSHKNYEGTCEIPESKYSPLGGPKPFECPSIQITSISPNC 120
CLPHHGLPSHSSVLSPSFQLQSHKNYEGTCEIPESKYSPLGGPKPFECPSIQITSISPNC
Sbjct: 61 CLPHHGLPSHSSVLSPSFQLQSHKNYEGTCEIPESKYSPLGGPKPFECPSIQITSISPNC 120
Query: 121 HQELDAHEDDLQINDPEREFLERPSRDHLYLPLEPSYRESSLSPSPASSISSRSWFSDAS 180
HQELDAHEDDLQINDPEREFLERPSRDHLYLPLEPSYRESSLSPSPASSISSRSWFSDAS
Sbjct: 121 HQELDAHEDDLQINDPEREFLERPSRDHLYLPLEPSYRESSLSPSPASSISSRSWFSDAS 180
Query: 181 SCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCPGEETWHQQYGLGHSLSPRQS 240
SCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCPGEETWHQQYGLGHSLSPRQS
Sbjct: 181 SCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCPGEETWHQQYGLGHSLSPRQS 240
Query: 241 PCHSPRSSVTDENWLSPRPASGPSSRPTSPCGKRRHSSAEVCYAGSLSPHHSPVPSPGHS 300
PCHSPRSSVTDENWLSPRPASGPSSRPTSPCGKRRHSSAEVCYAGSLSPHHSPVPSPGHS
Sbjct: 241 PCHSPRSSVTDENWLSPRPASGPSSRPTSPCGKRRHSSAEVCYAGSLSPHHSPVPSPGHS 300
Query: 301 PRGSVTEDTWLNASVHGGSGLGPAVFPFQYCVETDIPLKTRKTSEDQAAILPGKLELCSD 360
PRGSVTEDTWLNASVHGGSGLGPAVFPFQYCVETDIPLKTRKTSEDQAAILPGKLELCSD
Sbjct: 301 PRGSVTEDTWLNASVHGGSGLGPAVFPFQYCVETDIPLKTRKTSEDQAAILPGKLELCSD 360
Query: 361 DQGSLSPARETSIDDGLGSQYPLKKDSCGDQFLSVPSPFTWSKPKPGHTPIFRTSSLPPL 420
DQGSLSPARETSIDDGLGSQYPLKKDSCGDQFLSVPSPFTWSKPKPGHTPIFRTSSLPPL
Sbjct: 361 DQGSLSPARETSIDDGLGSQYPLKKDSCGDQFLSVPSPFTWSKPKPGHTPIFRTSSLPPL 420
Query: 421 DWPLPAHFGQCELKIEVQPKTHHRAHYETEGSRGAVKASTGGHPVVKLLGYNEKPINLQM 480
DWPLPAHFGQCELKIEVQPKTHHRAHYETEGSRGAVKASTGGHPVVKLLGYNEKPINLQM
Sbjct: 421 DWPLPAHFGQCELKIEVQPKTHHRAHYETEGSRGAVKASTGGHPVVKLLGYNEKPINLQM 480
Query: 481 FIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLLPENNMSASIDCAGI 540
FIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLLPENNMSASIDCAGI
Sbjct: 481 FIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLLPENNMSASIDCAGI 540
Query: 541 LKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELP 600
LKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELP
Sbjct: 541 LKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELP 600
Query: 601 HIEKYSINSCSVNGGHEMVVTGSNFLPESKIIFLEKGQDGRPQWEVEGKIIREKCQGAHI 660
HIEKYSINSCSVNGGHEMVVTGSNFLPESKIIFLEKGQDGRPQWEVEGKIIREKCQGAHI
Sbjct: 601 HIEKYSINSCSVNGGHEMVVTGSNFLPESKIIFLEKGQDGRPQWEVEGKIIREKCQGAHI 660
Query: 661 VLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTPVLMKQEHREEIDLSSVPSLPV 720
VLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTPVLMKQEHREEIDLSSVPSLPV
Sbjct: 661 VLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTPVLMKQEHREEIDLSSVPSLPV 720
Query: 721 PHPAQTQRPSSDSGCSHDSVLSGQRSLICSIPQTYASMVTSSHLPQLQCRDESVSKEQHM 780
PHPAQTQRPSSDSGCSHDSVLSGQRSLICSIPQTYASMVTSSHLPQLQCRDESVSKEQHM
Sbjct: 721 PHPAQTQRPSSDSGCSHDSVLSGQRSLICSIPQTYASMVTSSHLPQLQCRDESVSKEQHM 780
Query: 781 IPSPIVHQPFQVTPTPPVGSSYQPMQTNVVYNGPTCLPINAASSQEFDSVLFQQDATLSG 840
IPSPIVHQPFQVTPTPPVGSSYQPMQTNVVYNGPTCLPINAASSQEFDSVLFQQDATLSG
Sbjct: 781 IPSPIVHQPFQVTPTPPVGSSYQPMQTNVVYNGPTCLPINAASSQEFDSVLFQQDATLSG 840
Query: 841 LVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHSVHTLPHLQSMGYHCSNTGQRSLSSPVAD 900
LVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHSVHTLPHLQSMGYHCSNTGQRSLSSPVAD
Sbjct: 841 LVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHSVHTLPHLQSMGYHCSNTGQRSLSSPVAD 900
Query: 901 QITGQPSSQLQPITYGPSHSGSATTASPAASHPLASSPLSGPPSPQLQPMPYQSPSSGTA 960
QITGQPSSQLQPITYGPSHSGSATTASPAASHPLASSPLSGPPSPQLQPMPYQSPSSGTA
Sbjct: 901 QITGQPSSQLQPITYGPSHSGSATTASPAASHPLASSPLSGPPSPQLQPMPYQSPSSGTA 960
Query: 961 SSPSPATRMHSGQHSTQAQSTGQGGLSAPSSLICHSLCDPASFPPDGATVSIKPEPEDRE 1020
SSPSPATRMHSGQHSTQAQSTGQGGLSAPSSLICHSLCDPASFPPDGATVSIKPEPEDRE
Sbjct: 961 SSPSPATRMHSGQHSTQAQSTGQGGLSAPSSLICHSLCDPASFPPDGATVSIKPEPEDRE 1020
Query: 1021 PNFATIGLQDITLDDDQFISDL 1042
PNFATIGLQDITLDD +FISD+
Sbjct: 1021 PNFATIGLQDITLDDGKFISDM 1042
>gi|27886555 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 3 isoform 3 [Homo sapiens]
Length = 1065
Score = 2145 bits (5557), Expect = 0.0
Identities = 1038/1041 (99%), Positives = 1039/1041 (99%)
Query: 1 MTTANCGAHDELDFKLVFGEDGAPAPPPPGSRPADLEPDDCASIYIFNVDPPPSTLTTPL 60
MTTANCGAHDELDFKLVFGEDGAPAPPPPGSRPADLEPDDCASIYIFNVDPPPSTLTTPL
Sbjct: 1 MTTANCGAHDELDFKLVFGEDGAPAPPPPGSRPADLEPDDCASIYIFNVDPPPSTLTTPL 60
Query: 61 CLPHHGLPSHSSVLSPSFQLQSHKNYEGTCEIPESKYSPLGGPKPFECPSIQITSISPNC 120
CLPHHGLPSHSSVLSPSFQLQSHKNYEGTCEIPESKYSPLGGPKPFECPSIQITSISPNC
Sbjct: 61 CLPHHGLPSHSSVLSPSFQLQSHKNYEGTCEIPESKYSPLGGPKPFECPSIQITSISPNC 120
Query: 121 HQELDAHEDDLQINDPEREFLERPSRDHLYLPLEPSYRESSLSPSPASSISSRSWFSDAS 180
HQELDAHEDDLQINDPEREFLERPSRDHLYLPLEPSYRESSLSPSPASSISSRSWFSDAS
Sbjct: 121 HQELDAHEDDLQINDPEREFLERPSRDHLYLPLEPSYRESSLSPSPASSISSRSWFSDAS 180
Query: 181 SCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCPGEETWHQQYGLGHSLSPRQS 240
SCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCPGEETWHQQYGLGHSLSPRQS
Sbjct: 181 SCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCPGEETWHQQYGLGHSLSPRQS 240
Query: 241 PCHSPRSSVTDENWLSPRPASGPSSRPTSPCGKRRHSSAEVCYAGSLSPHHSPVPSPGHS 300
PCHSPRSSVTDENWLSPRPASGPSSRPTSPCGKRRHSSAEVCYAGSLSPHHSPVPSPGHS
Sbjct: 241 PCHSPRSSVTDENWLSPRPASGPSSRPTSPCGKRRHSSAEVCYAGSLSPHHSPVPSPGHS 300
Query: 301 PRGSVTEDTWLNASVHGGSGLGPAVFPFQYCVETDIPLKTRKTSEDQAAILPGKLELCSD 360
PRGSVTEDTWLNASVHGGSGLGPAVFPFQYCVETDIPLKTRKTSEDQAAILPGKLELCSD
Sbjct: 301 PRGSVTEDTWLNASVHGGSGLGPAVFPFQYCVETDIPLKTRKTSEDQAAILPGKLELCSD 360
Query: 361 DQGSLSPARETSIDDGLGSQYPLKKDSCGDQFLSVPSPFTWSKPKPGHTPIFRTSSLPPL 420
DQGSLSPARETSIDDGLGSQYPLKKDSCGDQFLSVPSPFTWSKPKPGHTPIFRTSSLPPL
Sbjct: 361 DQGSLSPARETSIDDGLGSQYPLKKDSCGDQFLSVPSPFTWSKPKPGHTPIFRTSSLPPL 420
Query: 421 DWPLPAHFGQCELKIEVQPKTHHRAHYETEGSRGAVKASTGGHPVVKLLGYNEKPINLQM 480
DWPLPAHFGQCELKIEVQPKTHHRAHYETEGSRGAVKASTGGHPVVKLLGYNEKPINLQM
Sbjct: 421 DWPLPAHFGQCELKIEVQPKTHHRAHYETEGSRGAVKASTGGHPVVKLLGYNEKPINLQM 480
Query: 481 FIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLLPENNMSASIDCAGI 540
FIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLLPENNMSASIDCAGI
Sbjct: 481 FIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLLPENNMSASIDCAGI 540
Query: 541 LKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELP 600
LKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELP
Sbjct: 541 LKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELP 600
Query: 601 HIEKYSINSCSVNGGHEMVVTGSNFLPESKIIFLEKGQDGRPQWEVEGKIIREKCQGAHI 660
HIEKYSINSCSVNGGHEMVVTGSNFLPESKIIFLEKGQDGRPQWEVEGKIIREKCQGAHI
Sbjct: 601 HIEKYSINSCSVNGGHEMVVTGSNFLPESKIIFLEKGQDGRPQWEVEGKIIREKCQGAHI 660
Query: 661 VLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTPVLMKQEHREEIDLSSVPSLPV 720
VLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTPVLMKQEHREEIDLSSVPSLPV
Sbjct: 661 VLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTPVLMKQEHREEIDLSSVPSLPV 720
Query: 721 PHPAQTQRPSSDSGCSHDSVLSGQRSLICSIPQTYASMVTSSHLPQLQCRDESVSKEQHM 780
PHPAQTQRPSSDSGCSHDSVLSGQRSLICSIPQTYASMVTSSHLPQLQCRDESVSKEQHM
Sbjct: 721 PHPAQTQRPSSDSGCSHDSVLSGQRSLICSIPQTYASMVTSSHLPQLQCRDESVSKEQHM 780
Query: 781 IPSPIVHQPFQVTPTPPVGSSYQPMQTNVVYNGPTCLPINAASSQEFDSVLFQQDATLSG 840
IPSPIVHQPFQVTPTPPVGSSYQPMQTNVVYNGPTCLPINAASSQEFDSVLFQQDATLSG
Sbjct: 781 IPSPIVHQPFQVTPTPPVGSSYQPMQTNVVYNGPTCLPINAASSQEFDSVLFQQDATLSG 840
Query: 841 LVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHSVHTLPHLQSMGYHCSNTGQRSLSSPVAD 900
LVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHSVHTLPHLQSMGYHCSNTGQRSLSSPVAD
Sbjct: 841 LVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHSVHTLPHLQSMGYHCSNTGQRSLSSPVAD 900
Query: 901 QITGQPSSQLQPITYGPSHSGSATTASPAASHPLASSPLSGPPSPQLQPMPYQSPSSGTA 960
QITGQPSSQLQPITYGPSHSGSATTASPAASHPLASSPLSGPPSPQLQPMPYQSPSSGTA
Sbjct: 901 QITGQPSSQLQPITYGPSHSGSATTASPAASHPLASSPLSGPPSPQLQPMPYQSPSSGTA 960
Query: 961 SSPSPATRMHSGQHSTQAQSTGQGGLSAPSSLICHSLCDPASFPPDGATVSIKPEPEDRE 1020
SSPSPATRMHSGQHSTQAQSTGQGGLSAPSSLICHSLCDPASFPPDGATVSIKPEPEDRE
Sbjct: 961 SSPSPATRMHSGQHSTQAQSTGQGGLSAPSSLICHSLCDPASFPPDGATVSIKPEPEDRE 1020
Query: 1021 PNFATIGLQDITLDDDQFISD 1041
PNFATIGLQDITLDDD F S+
Sbjct: 1021 PNFATIGLQDITLDDDLFTSN 1041
>gi|27886561 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 3 isoform 1 [Homo sapiens]
Length = 1075
Score = 2139 bits (5543), Expect = 0.0
Identities = 1035/1035 (100%), Positives = 1035/1035 (100%)
Query: 1 MTTANCGAHDELDFKLVFGEDGAPAPPPPGSRPADLEPDDCASIYIFNVDPPPSTLTTPL 60
MTTANCGAHDELDFKLVFGEDGAPAPPPPGSRPADLEPDDCASIYIFNVDPPPSTLTTPL
Sbjct: 1 MTTANCGAHDELDFKLVFGEDGAPAPPPPGSRPADLEPDDCASIYIFNVDPPPSTLTTPL 60
Query: 61 CLPHHGLPSHSSVLSPSFQLQSHKNYEGTCEIPESKYSPLGGPKPFECPSIQITSISPNC 120
CLPHHGLPSHSSVLSPSFQLQSHKNYEGTCEIPESKYSPLGGPKPFECPSIQITSISPNC
Sbjct: 61 CLPHHGLPSHSSVLSPSFQLQSHKNYEGTCEIPESKYSPLGGPKPFECPSIQITSISPNC 120
Query: 121 HQELDAHEDDLQINDPEREFLERPSRDHLYLPLEPSYRESSLSPSPASSISSRSWFSDAS 180
HQELDAHEDDLQINDPEREFLERPSRDHLYLPLEPSYRESSLSPSPASSISSRSWFSDAS
Sbjct: 121 HQELDAHEDDLQINDPEREFLERPSRDHLYLPLEPSYRESSLSPSPASSISSRSWFSDAS 180
Query: 181 SCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCPGEETWHQQYGLGHSLSPRQS 240
SCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCPGEETWHQQYGLGHSLSPRQS
Sbjct: 181 SCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCPGEETWHQQYGLGHSLSPRQS 240
Query: 241 PCHSPRSSVTDENWLSPRPASGPSSRPTSPCGKRRHSSAEVCYAGSLSPHHSPVPSPGHS 300
PCHSPRSSVTDENWLSPRPASGPSSRPTSPCGKRRHSSAEVCYAGSLSPHHSPVPSPGHS
Sbjct: 241 PCHSPRSSVTDENWLSPRPASGPSSRPTSPCGKRRHSSAEVCYAGSLSPHHSPVPSPGHS 300
Query: 301 PRGSVTEDTWLNASVHGGSGLGPAVFPFQYCVETDIPLKTRKTSEDQAAILPGKLELCSD 360
PRGSVTEDTWLNASVHGGSGLGPAVFPFQYCVETDIPLKTRKTSEDQAAILPGKLELCSD
Sbjct: 301 PRGSVTEDTWLNASVHGGSGLGPAVFPFQYCVETDIPLKTRKTSEDQAAILPGKLELCSD 360
Query: 361 DQGSLSPARETSIDDGLGSQYPLKKDSCGDQFLSVPSPFTWSKPKPGHTPIFRTSSLPPL 420
DQGSLSPARETSIDDGLGSQYPLKKDSCGDQFLSVPSPFTWSKPKPGHTPIFRTSSLPPL
Sbjct: 361 DQGSLSPARETSIDDGLGSQYPLKKDSCGDQFLSVPSPFTWSKPKPGHTPIFRTSSLPPL 420
Query: 421 DWPLPAHFGQCELKIEVQPKTHHRAHYETEGSRGAVKASTGGHPVVKLLGYNEKPINLQM 480
DWPLPAHFGQCELKIEVQPKTHHRAHYETEGSRGAVKASTGGHPVVKLLGYNEKPINLQM
Sbjct: 421 DWPLPAHFGQCELKIEVQPKTHHRAHYETEGSRGAVKASTGGHPVVKLLGYNEKPINLQM 480
Query: 481 FIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLLPENNMSASIDCAGI 540
FIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLLPENNMSASIDCAGI
Sbjct: 481 FIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLLPENNMSASIDCAGI 540
Query: 541 LKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELP 600
LKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELP
Sbjct: 541 LKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELP 600
Query: 601 HIEKYSINSCSVNGGHEMVVTGSNFLPESKIIFLEKGQDGRPQWEVEGKIIREKCQGAHI 660
HIEKYSINSCSVNGGHEMVVTGSNFLPESKIIFLEKGQDGRPQWEVEGKIIREKCQGAHI
Sbjct: 601 HIEKYSINSCSVNGGHEMVVTGSNFLPESKIIFLEKGQDGRPQWEVEGKIIREKCQGAHI 660
Query: 661 VLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTPVLMKQEHREEIDLSSVPSLPV 720
VLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTPVLMKQEHREEIDLSSVPSLPV
Sbjct: 661 VLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTPVLMKQEHREEIDLSSVPSLPV 720
Query: 721 PHPAQTQRPSSDSGCSHDSVLSGQRSLICSIPQTYASMVTSSHLPQLQCRDESVSKEQHM 780
PHPAQTQRPSSDSGCSHDSVLSGQRSLICSIPQTYASMVTSSHLPQLQCRDESVSKEQHM
Sbjct: 721 PHPAQTQRPSSDSGCSHDSVLSGQRSLICSIPQTYASMVTSSHLPQLQCRDESVSKEQHM 780
Query: 781 IPSPIVHQPFQVTPTPPVGSSYQPMQTNVVYNGPTCLPINAASSQEFDSVLFQQDATLSG 840
IPSPIVHQPFQVTPTPPVGSSYQPMQTNVVYNGPTCLPINAASSQEFDSVLFQQDATLSG
Sbjct: 781 IPSPIVHQPFQVTPTPPVGSSYQPMQTNVVYNGPTCLPINAASSQEFDSVLFQQDATLSG 840
Query: 841 LVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHSVHTLPHLQSMGYHCSNTGQRSLSSPVAD 900
LVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHSVHTLPHLQSMGYHCSNTGQRSLSSPVAD
Sbjct: 841 LVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHSVHTLPHLQSMGYHCSNTGQRSLSSPVAD 900
Query: 901 QITGQPSSQLQPITYGPSHSGSATTASPAASHPLASSPLSGPPSPQLQPMPYQSPSSGTA 960
QITGQPSSQLQPITYGPSHSGSATTASPAASHPLASSPLSGPPSPQLQPMPYQSPSSGTA
Sbjct: 901 QITGQPSSQLQPITYGPSHSGSATTASPAASHPLASSPLSGPPSPQLQPMPYQSPSSGTA 960
Query: 961 SSPSPATRMHSGQHSTQAQSTGQGGLSAPSSLICHSLCDPASFPPDGATVSIKPEPEDRE 1020
SSPSPATRMHSGQHSTQAQSTGQGGLSAPSSLICHSLCDPASFPPDGATVSIKPEPEDRE
Sbjct: 961 SSPSPATRMHSGQHSTQAQSTGQGGLSAPSSLICHSLCDPASFPPDGATVSIKPEPEDRE 1020
Query: 1021 PNFATIGLQDITLDD 1035
PNFATIGLQDITLDD
Sbjct: 1021 PNFATIGLQDITLDD 1035
>gi|209862845 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 4 isoform 1 [Homo sapiens]
Length = 964
Score = 591 bits (1523), Expect = e-168
Identities = 368/783 (46%), Positives = 454/783 (57%), Gaps = 99/783 (12%)
Query: 1 MTTANCGAHDELDFKLVFGEDGAPAPPPPGSRPADLEPDDCASIYIFNVDPPPSTLTTPL 60
M A+C +EL+FKLVFGE+ P G +L+ +D + PP P+
Sbjct: 64 MGAASC-EDEELEFKLVFGEEKEAPPLGAGGLGEELDSEDAPPCCRLALGEPPPYGAAPI 122
Query: 61 CLPHHGLPSHSSVLSPSFQLQSHKNYEGTCEIPESKYSPLGGP----------KPFECPS 110
+P P P S GT E ++ LGGP + ECPS
Sbjct: 123 GIPRPPPPRPGMHSPPPRPAPS----PGTWESQPARSVRLGGPGGGAGGAGGGRVLECPS 178
Query: 111 IQITSISPNCHQELDAHEDDLQINDPEREFLERPSRDHLYLPLEP--SYRESS------- 161
I+ITSISP E + D + + RD Y P E YRE+
Sbjct: 179 IRITSISPT-------PEPPAALEDNPDAWGDGSPRD--YPPPEGFGGYREAGGQGGGAF 229
Query: 162 LSPSP-ASSISSRSWFSDASSCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCP 220
SPSP +SS+SS S+FSDAS +L D+V+SELNEAA+RF LGSPL SP SP
Sbjct: 230 FSPSPGSSSLSSWSFFSDASDEAALYAACDEVESELNEAASRFGLGSPLPSPRASPRPWT 289
Query: 221 GEETWHQQYGLGHSLSPRQSPCHSPRSSVTDENWL-----SPRPASGPSSRPTSPCGKRR 275
E+ W YG SP +++WL P PAS RP SPCGKRR
Sbjct: 290 PEDPW-SLYG------------PSPGGRGPEDSWLLLSAPGPTPAS---PRPASPCGKRR 333
Query: 276 HSSA--------EVCYAGSLSPHHSPVPSPGHSPRGSVTEDTWLNASVHGGSGLGPAVFP 327
+SS+ + GSL S P P P A G G P
Sbjct: 334 YSSSGTPSSASPALSRRGSLGEEGSEPPPPPPLPL----------ARDPGSPG------P 377
Query: 328 FQYC---VETDIPLKTRKTSEDQAAILPGKLELCSDDQGSLSPARETSIDDGLGSQYPLK 384
F Y IP KTR+TS +QA LP E S + G L E S+ GS +
Sbjct: 378 FDYVGAPPAESIPQKTRRTSSEQAVALPRSEEPASCN-GKLPLGAEESVAPPGGS----R 432
Query: 385 KDSCGDQFLSVPSPFTWSKPK-PGHTPIFRTSSLPPLDWPLPAHFGQCELKIEVQPKTHH 443
K+ G +L+VPSP WSK + GH+PIFRTS+LPPLDWPLP+ + Q EL+IEVQP+ HH
Sbjct: 433 KEVAGMDYLAVPSPLAWSKARIGGHSPIFRTSALPPLDWPLPSQYEQLELRIEVQPRAHH 492
Query: 444 RAHYETEGSRGAVKASTGGHPVVKLLGYNEKPINLQMFIGTADDRYLRPHAFYQVHRITG 503
RAHYETEGSRGAVKA+ GGHPVVKLLGY+EKP+ LQMFIGTAD+R LRPHAFYQVHRITG
Sbjct: 493 RAHYETEGSRGAVKAAPGGHPVVKLLGYSEKPLTLQMFIGTADERNLRPHAFYQVHRITG 552
Query: 504 KTVATASQEIIIASTKVLEIPLLPENNMSASIDCAGILKLRNSDIELRKGETDIGRKNTR 563
K VATAS E +++ TKVLE+ LLPENNM+A+IDCAGILKLRNSDIELRKGETDIGRKNTR
Sbjct: 553 KMVATASYEAVVSGTKVLEMTLLPENNMAANIDCAGILKLRNSDIELRKGETDIGRKNTR 612
Query: 564 VRLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELPHIEKYSINSCSVNGGHEMVVTGS 623
VRLVFRVH+PQ GKV+S+Q AS+P+ECSQRSAQELP +E YS ++CSV GG E+V+TGS
Sbjct: 613 VRLVFRVHVPQGGGKVVSVQAASVPIECSQRSAQELPQVEAYSPSACSVRGGEELVLTGS 672
Query: 624 NFLPESKIIFLEKGQDGRPQWEVEGKIIREKCQGAHIVLEVPPYHNPAVTAAVQVHFYLC 683
NFLP+SK++F+E+G DG+ QWE E + R + + L VP Y N V+ VQV+FY+
Sbjct: 673 NFLPDSKVVFIERGPDGKLQWEEEATVNRLQSNEVTLTLTVPEYSNKRVSRPVQVYFYVS 732
Query: 684 NGKRKKSQSQRFTYTPVLMKQEHREEIDLSSVPSLPV-----------PHPAQTQRPSSD 732
NG+RK+S +Q F + PV+ K+E + L PS P P P D
Sbjct: 733 NGRRKRSPTQSFRFLPVICKEEPLPDSSLRGFPSASATPFGTDMDFSPPRPPYPSYPHED 792
Query: 733 SGC 735
C
Sbjct: 793 PAC 795
>gi|27886563 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 4 isoform 2 [Homo sapiens]
Length = 902
Score = 591 bits (1523), Expect = e-168
Identities = 368/783 (46%), Positives = 454/783 (57%), Gaps = 99/783 (12%)
Query: 1 MTTANCGAHDELDFKLVFGEDGAPAPPPPGSRPADLEPDDCASIYIFNVDPPPSTLTTPL 60
M A+C +EL+FKLVFGE+ P G +L+ +D + PP P+
Sbjct: 1 MGAASC-EDEELEFKLVFGEEKEAPPLGAGGLGEELDSEDAPPCCRLALGEPPPYGAAPI 59
Query: 61 CLPHHGLPSHSSVLSPSFQLQSHKNYEGTCEIPESKYSPLGGP----------KPFECPS 110
+P P P S GT E ++ LGGP + ECPS
Sbjct: 60 GIPRPPPPRPGMHSPPPRPAPS----PGTWESQPARSVRLGGPGGGAGGAGGGRVLECPS 115
Query: 111 IQITSISPNCHQELDAHEDDLQINDPEREFLERPSRDHLYLPLEP--SYRESS------- 161
I+ITSISP E + D + + RD Y P E YRE+
Sbjct: 116 IRITSISPT-------PEPPAALEDNPDAWGDGSPRD--YPPPEGFGGYREAGGQGGGAF 166
Query: 162 LSPSP-ASSISSRSWFSDASSCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCP 220
SPSP +SS+SS S+FSDAS +L D+V+SELNEAA+RF LGSPL SP SP
Sbjct: 167 FSPSPGSSSLSSWSFFSDASDEAALYAACDEVESELNEAASRFGLGSPLPSPRASPRPWT 226
Query: 221 GEETWHQQYGLGHSLSPRQSPCHSPRSSVTDENWL-----SPRPASGPSSRPTSPCGKRR 275
E+ W YG SP +++WL P PAS RP SPCGKRR
Sbjct: 227 PEDPW-SLYG------------PSPGGRGPEDSWLLLSAPGPTPAS---PRPASPCGKRR 270
Query: 276 HSSA--------EVCYAGSLSPHHSPVPSPGHSPRGSVTEDTWLNASVHGGSGLGPAVFP 327
+SS+ + GSL S P P P A G G P
Sbjct: 271 YSSSGTPSSASPALSRRGSLGEEGSEPPPPPPLPL----------ARDPGSPG------P 314
Query: 328 FQYC---VETDIPLKTRKTSEDQAAILPGKLELCSDDQGSLSPARETSIDDGLGSQYPLK 384
F Y IP KTR+TS +QA LP E S + G L E S+ GS +
Sbjct: 315 FDYVGAPPAESIPQKTRRTSSEQAVALPRSEEPASCN-GKLPLGAEESVAPPGGS----R 369
Query: 385 KDSCGDQFLSVPSPFTWSKPK-PGHTPIFRTSSLPPLDWPLPAHFGQCELKIEVQPKTHH 443
K+ G +L+VPSP WSK + GH+PIFRTS+LPPLDWPLP+ + Q EL+IEVQP+ HH
Sbjct: 370 KEVAGMDYLAVPSPLAWSKARIGGHSPIFRTSALPPLDWPLPSQYEQLELRIEVQPRAHH 429
Query: 444 RAHYETEGSRGAVKASTGGHPVVKLLGYNEKPINLQMFIGTADDRYLRPHAFYQVHRITG 503
RAHYETEGSRGAVKA+ GGHPVVKLLGY+EKP+ LQMFIGTAD+R LRPHAFYQVHRITG
Sbjct: 430 RAHYETEGSRGAVKAAPGGHPVVKLLGYSEKPLTLQMFIGTADERNLRPHAFYQVHRITG 489
Query: 504 KTVATASQEIIIASTKVLEIPLLPENNMSASIDCAGILKLRNSDIELRKGETDIGRKNTR 563
K VATAS E +++ TKVLE+ LLPENNM+A+IDCAGILKLRNSDIELRKGETDIGRKNTR
Sbjct: 490 KMVATASYEAVVSGTKVLEMTLLPENNMAANIDCAGILKLRNSDIELRKGETDIGRKNTR 549
Query: 564 VRLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELPHIEKYSINSCSVNGGHEMVVTGS 623
VRLVFRVH+PQ GKV+S+Q AS+P+ECSQRSAQELP +E YS ++CSV GG E+V+TGS
Sbjct: 550 VRLVFRVHVPQGGGKVVSVQAASVPIECSQRSAQELPQVEAYSPSACSVRGGEELVLTGS 609
Query: 624 NFLPESKIIFLEKGQDGRPQWEVEGKIIREKCQGAHIVLEVPPYHNPAVTAAVQVHFYLC 683
NFLP+SK++F+E+G DG+ QWE E + R + + L VP Y N V+ VQV+FY+
Sbjct: 610 NFLPDSKVVFIERGPDGKLQWEEEATVNRLQSNEVTLTLTVPEYSNKRVSRPVQVYFYVS 669
Query: 684 NGKRKKSQSQRFTYTPVLMKQEHREEIDLSSVPSLPV-----------PHPAQTQRPSSD 732
NG+RK+S +Q F + PV+ K+E + L PS P P P D
Sbjct: 670 NGRRKRSPTQSFRFLPVICKEEPLPDSSLRGFPSASATPFGTDMDFSPPRPPYPSYPHED 729
Query: 733 SGC 735
C
Sbjct: 730 PAC 732
>gi|19923350 nuclear factor of activated T-cells, cytosolic
component 1 isoform B [Homo sapiens]
Length = 825
Score = 561 bits (1446), Expect = e-159
Identities = 353/753 (46%), Positives = 452/753 (60%), Gaps = 69/753 (9%)
Query: 19 GEDGAPAPPPPGS-RPADLEPDDCASIYIFNVDPPPSTLTTPLCLPHHGLPSHSSVLSPS 77
GE PAP G+ + A+ E AS + P P+ +T L P H L + + + P
Sbjct: 24 GETLGPAPRAGGTMKSAEEEHYGYASSNVSPALPLPTAHST-LPAPCHNLQTSTPGIIPP 82
Query: 78 FQLQSHKNYEGTCEIPESKY-------SPLGGPKPFECPSIQITSISPNCHQELDAHEDD 130
S Y + + Y P G P E P I+ITS H + D
Sbjct: 83 ADHPS--GYGAALDGGPAGYFLSSGHTRPDGAPA-LESPRIEITSCLGLYHNN-NQFFHD 138
Query: 131 LQINDPEREFLERPSRDHLYLPLEPSYRESSLSPSPASSISSRSWFSDASSCESLSHIYD 190
+++ D PS L LP +YR+ S SPASS+SSRS S+ASS ES
Sbjct: 139 VEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCL-SPASSLSSRSCNSEASSYES------ 191
Query: 191 DVDSELNEAAARFTLGSPLTSPGGSPGGCPGEETWHQQYGLGHSL-------SPRQSPCH 243
+ SP TSP SP C +T + G L SPR SP
Sbjct: 192 ---------NYSYPYASPQTSPWQSP--CVSPKTTDPEEGFPRGLGACTLLGSPRHSPST 240
Query: 244 SPRSSVTDENWLSPRPASGPSSRPTSPCGKRRHS--SAEVCYAGSLSPHHSPVPSPGHSP 301
SPR+SVT+E+WL R SSRP SPC KR++S + Y SPHHSP PSP SP
Sbjct: 241 SPRASVTEESWLGAR-----SSRPASPCNKRKYSLNGRQPPY----SPHHSPTPSPHGSP 291
Query: 302 RGSVTEDTWL-NASVHGGSGLGPAVFPFQYCVETD----IPLKTRKTSEDQAAILPGKLE 356
R SVT+D+WL N + + S + A+ D +P+K+RKT+ +Q + K+E
Sbjct: 292 RVSVTDDSWLGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVE 351
Query: 357 LCSDDQGSLSPARETSIDDGLGSQYPLKKDSCGDQFLSVPS-PFTWSKPKPGHTPIFRTS 415
+D GS P + + +D Q+ K C DQ+L+VP P+ W+KPKP + +
Sbjct: 352 PVGEDLGSPPPPADFAPEDYSSFQHIRKGGFC-DQYLAVPQHPYQWAKPKPLSPTSYMSP 410
Query: 416 SLPPLDWPLPAHFGQCELKIEVQPKTHHRAHYETEGSRGAVKASTGGHPVVKLLGYNE-K 474
+LP LDW LP+H G EL+IEVQPK+HHRAHYETEGSRGAVKAS GGHP+V+L GY E +
Sbjct: 411 TLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENE 470
Query: 475 PINLQMFIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLLPENNMSAS 534
P+ LQ+FIGTADDR LRPHAFYQVHRITGKTV+T S E I+++TKVLEIPLLPEN+M A
Sbjct: 471 PLMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAV 530
Query: 535 IDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQR 594
IDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVH+PQPSG+ LSLQ+AS P+ECSQR
Sbjct: 531 IDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQR 590
Query: 595 SAQELPHIEKYSINSCSVNGGHEMVVTGSNFLPESKIIFLEKGQDGRPQWEVEGKIIREK 654
SAQELP +EK S +S V GG +MV++G NFL +SK+IF+EK DG WE+E K R+
Sbjct: 591 SAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDL 650
Query: 655 CQGAHIVLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTPV---LMKQEHREEID 711
C+ +V+E+PP+ N +T+ V V FY+CNGKRK+SQ QRFTY P ++K E ++ +
Sbjct: 651 CKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDDYE 710
Query: 712 LS------SVPSLPVPHPAQTQR---PSSDSGC 735
+ S P+P P +Q+ P S C
Sbjct: 711 PAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSC 743
>gi|27502386 nuclear factor of activated T-cells, cytosolic
component 1 isoform C [Homo sapiens]
Length = 930
Score = 559 bits (1440), Expect = e-159
Identities = 330/662 (49%), Positives = 418/662 (63%), Gaps = 57/662 (8%)
Query: 102 GPKPFECPSIQITSISPNCHQELDAHEDDLQINDPEREFLERPSRDHLYLPLEPSYRESS 161
G E P I+ITS H + D+++ D PS L LP +YR+ S
Sbjct: 98 GAPALESPRIEITSCLGLYHNN-NQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPS 156
Query: 162 LSPSPASSISSRSWFSDASSCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCPG 221
SPASS+SSRS S+ASS ES + SP TSP SP C
Sbjct: 157 CL-SPASSLSSRSCNSEASSYES---------------NYSYPYASPQTSPWQSP--CVS 198
Query: 222 EETWHQQYGLGHSL-------SPRQSPCHSPRSSVTDENWLSPRPASGPSSRPTSPCGKR 274
+T + G L SPR SP SPR+SVT+E+WL R SSRP SPC KR
Sbjct: 199 PKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGAR-----SSRPASPCNKR 253
Query: 275 RHS--SAEVCYAGSLSPHHSPVPSPGHSPRGSVTEDTWL-NASVHGGSGLGPAVFPFQYC 331
++S + Y SPHHSP PSP SPR SVT+D+WL N + + S + A+
Sbjct: 254 KYSLNGRQPPY----SPHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIVAAINALTTD 309
Query: 332 VETD----IPLKTRKTSEDQAAILPGKLELCSDDQGSLSPARETSIDDGLGSQYPLKKDS 387
D +P+K+RKT+ +Q + K+E +D GS P + + +D Q+ K
Sbjct: 310 SSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSSFQHIRKGGF 369
Query: 388 CGDQFLSVPS-PFTWSKPKPGHTPIFRTSSLPPLDWPLPAHFGQCELKIEVQPKTHHRAH 446
C DQ+L+VP P+ W+KPKP + + +LP LDW LP+H G EL+IEVQPK+HHRAH
Sbjct: 370 C-DQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLPSHSGPYELRIEVQPKSHHRAH 428
Query: 447 YETEGSRGAVKASTGGHPVVKLLGYNE-KPINLQMFIGTADDRYLRPHAFYQVHRITGKT 505
YETEGSRGAVKAS GGHP+V+L GY E +P+ LQ+FIGTADDR LRPHAFYQVHRITGKT
Sbjct: 429 YETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQVHRITGKT 488
Query: 506 VATASQEIIIASTKVLEIPLLPENNMSASIDCAGILKLRNSDIELRKGETDIGRKNTRVR 565
V+T S E I+++TKVLEIPLLPEN+M A IDCAGILKLRNSDIELRKGETDIGRKNTRVR
Sbjct: 489 VSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLRNSDIELRKGETDIGRKNTRVR 548
Query: 566 LVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELPHIEKYSINSCSVNGGHEMVVTGSNF 625
LVFRVH+PQPSG+ LSLQ+AS P+ECSQRSAQELP +EK S +S V GG +MV++G NF
Sbjct: 549 LVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEKQSTDSYPVVGGKKMVLSGHNF 608
Query: 626 LPESKIIFLEKGQDGRPQWEVEGKIIREKCQGAHIVLEVPPYHNPAVTAAVQVHFYLCNG 685
L +SK+IF+EK DG WE+E K R+ C+ +V+E+PP+ N +T+ V V FY+CNG
Sbjct: 609 LQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCNG 668
Query: 686 KRKKSQSQRFTYTPV---LMKQEHREEIDLS------SVPSLPVPHPAQTQR---PSSDS 733
KRK+SQ QRFTY P ++K E ++ + + S P+P P +Q+ P S
Sbjct: 669 KRKRSQYQRFTYLPANVPIIKTEPTDDYEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPS 728
Query: 734 GC 735
C
Sbjct: 729 SC 730
>gi|27502391 nuclear factor of activated T-cells, cytosolic
component 1 isoform E [Homo sapiens]
Length = 812
Score = 559 bits (1440), Expect = e-159
Identities = 330/662 (49%), Positives = 418/662 (63%), Gaps = 57/662 (8%)
Query: 102 GPKPFECPSIQITSISPNCHQELDAHEDDLQINDPEREFLERPSRDHLYLPLEPSYRESS 161
G E P I+ITS H + D+++ D PS L LP +YR+ S
Sbjct: 98 GAPALESPRIEITSCLGLYHNN-NQFFHDVEVEDVLPSSKRSPSTATLSLPSLEAYRDPS 156
Query: 162 LSPSPASSISSRSWFSDASSCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCPG 221
SPASS+SSRS S+ASS ES + SP TSP SP C
Sbjct: 157 CL-SPASSLSSRSCNSEASSYES---------------NYSYPYASPQTSPWQSP--CVS 198
Query: 222 EETWHQQYGLGHSL-------SPRQSPCHSPRSSVTDENWLSPRPASGPSSRPTSPCGKR 274
+T + G L SPR SP SPR+SVT+E+WL R SSRP SPC KR
Sbjct: 199 PKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGAR-----SSRPASPCNKR 253
Query: 275 RHS--SAEVCYAGSLSPHHSPVPSPGHSPRGSVTEDTWL-NASVHGGSGLGPAVFPFQYC 331
++S + Y SPHHSP PSP SPR SVT+D+WL N + + S + A+
Sbjct: 254 KYSLNGRQPPY----SPHHSPTPSPHGSPRVSVTDDSWLGNTTQYTSSAIVAAINALTTD 309
Query: 332 VETD----IPLKTRKTSEDQAAILPGKLELCSDDQGSLSPARETSIDDGLGSQYPLKKDS 387
D +P+K+RKT+ +Q + K+E +D GS P + + +D Q+ K
Sbjct: 310 SSLDLGDGVPVKSRKTTLEQPPSVALKVEPVGEDLGSPPPPADFAPEDYSSFQHIRKGGF 369
Query: 388 CGDQFLSVPS-PFTWSKPKPGHTPIFRTSSLPPLDWPLPAHFGQCELKIEVQPKTHHRAH 446
C DQ+L+VP P+ W+KPKP + + +LP LDW LP+H G EL+IEVQPK+HHRAH
Sbjct: 370 C-DQYLAVPQHPYQWAKPKPLSPTSYMSPTLPALDWQLPSHSGPYELRIEVQPKSHHRAH 428
Query: 447 YETEGSRGAVKASTGGHPVVKLLGYNE-KPINLQMFIGTADDRYLRPHAFYQVHRITGKT 505
YETEGSRGAVKAS GGHP+V+L GY E +P+ LQ+FIGTADDR LRPHAFYQVHRITGKT
Sbjct: 429 YETEGSRGAVKASAGGHPIVQLHGYLENEPLMLQLFIGTADDRLLRPHAFYQVHRITGKT 488
Query: 506 VATASQEIIIASTKVLEIPLLPENNMSASIDCAGILKLRNSDIELRKGETDIGRKNTRVR 565
V+T S E I+++TKVLEIPLLPEN+M A IDCAGILKLRNSDIELRKGETDIGRKNTRVR
Sbjct: 489 VSTTSHEAILSNTKVLEIPLLPENSMRAVIDCAGILKLRNSDIELRKGETDIGRKNTRVR 548
Query: 566 LVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELPHIEKYSINSCSVNGGHEMVVTGSNF 625
LVFRVH+PQPSG+ LSLQ+AS P+ECSQRSAQELP +EK S +S V GG +MV++G NF
Sbjct: 549 LVFRVHVPQPSGRTLSLQVASNPIECSQRSAQELPLVEKQSTDSYPVVGGKKMVLSGHNF 608
Query: 626 LPESKIIFLEKGQDGRPQWEVEGKIIREKCQGAHIVLEVPPYHNPAVTAAVQVHFYLCNG 685
L +SK+IF+EK DG WE+E K R+ C+ +V+E+PP+ N +T+ V V FY+CNG
Sbjct: 609 LQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKPNSLVVEIPPFRNQRITSPVHVSFYVCNG 668
Query: 686 KRKKSQSQRFTYTPV---LMKQEHREEIDLS------SVPSLPVPHPAQTQR---PSSDS 733
KRK+SQ QRFTY P ++K E ++ + + S P+P P +Q+ P S
Sbjct: 669 KRKRSQYQRFTYLPANVPIIKTEPTDDYEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPS 728
Query: 734 GC 735
C
Sbjct: 729 SC 730
>gi|27502393 nuclear factor of activated T-cells, cytosolic
component 1 isoform A [Homo sapiens]
Length = 716
Score = 558 bits (1439), Expect = e-159
Identities = 343/705 (48%), Positives = 433/705 (61%), Gaps = 57/705 (8%)
Query: 19 GEDGAPAPPPPGS-RPADLEPDDCASIYIFNVDPPPSTLTTPLCLPHHGLPSHSSVLSPS 77
GE PAP G+ + A+ E AS + P P+ +T L P H L + + + P
Sbjct: 24 GETLGPAPRAGGTMKSAEEEHYGYASSNVSPALPLPTAHST-LPAPCHNLQTSTPGIIPP 82
Query: 78 FQLQSHKNYEGTCEIPESKY-------SPLGGPKPFECPSIQITSISPNCHQELDAHEDD 130
S Y + + Y P G P E P I+ITS H + D
Sbjct: 83 ADHPS--GYGAALDGGPAGYFLSSGHTRPDGAPA-LESPRIEITSCLGLYHNN-NQFFHD 138
Query: 131 LQINDPEREFLERPSRDHLYLPLEPSYRESSLSPSPASSISSRSWFSDASSCESLSHIYD 190
+++ D PS L LP +YR+ S SPASS+SSRS S+ASS ES
Sbjct: 139 VEVEDVLPSSKRSPSTATLSLPSLEAYRDPSCL-SPASSLSSRSCNSEASSYES------ 191
Query: 191 DVDSELNEAAARFTLGSPLTSPGGSPGGCPGEETWHQQYGLGHSL-------SPRQSPCH 243
+ SP TSP SP C +T + G L SPR SP
Sbjct: 192 ---------NYSYPYASPQTSPWQSP--CVSPKTTDPEEGFPRGLGACTLLGSPRHSPST 240
Query: 244 SPRSSVTDENWLSPRPASGPSSRPTSPCGKRRHS--SAEVCYAGSLSPHHSPVPSPGHSP 301
SPR+SVT+E+WL R SSRP SPC KR++S + Y SPHHSP PSP SP
Sbjct: 241 SPRASVTEESWLGAR-----SSRPASPCNKRKYSLNGRQPPY----SPHHSPTPSPHGSP 291
Query: 302 RGSVTEDTWL-NASVHGGSGLGPAVFPFQYCVETD----IPLKTRKTSEDQAAILPGKLE 356
R SVT+D+WL N + + S + A+ D +P+K+RKT+ +Q + K+E
Sbjct: 292 RVSVTDDSWLGNTTQYTSSAIVAAINALTTDSSLDLGDGVPVKSRKTTLEQPPSVALKVE 351
Query: 357 LCSDDQGSLSPARETSIDDGLGSQYPLKKDSCGDQFLSVPS-PFTWSKPKPGHTPIFRTS 415
+D GS P + + +D Q+ K C DQ+L+VP P+ W+KPKP + +
Sbjct: 352 PVGEDLGSPPPPADFAPEDYSSFQHIRKGGFC-DQYLAVPQHPYQWAKPKPLSPTSYMSP 410
Query: 416 SLPPLDWPLPAHFGQCELKIEVQPKTHHRAHYETEGSRGAVKASTGGHPVVKLLGYNE-K 474
+LP LDW LP+H G EL+IEVQPK+HHRAHYETEGSRGAVKAS GGHP+V+L GY E +
Sbjct: 411 TLPALDWQLPSHSGPYELRIEVQPKSHHRAHYETEGSRGAVKASAGGHPIVQLHGYLENE 470
Query: 475 PINLQMFIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLLPENNMSAS 534
P+ LQ+FIGTADDR LRPHAFYQVHRITGKTV+T S E I+++TKVLEIPLLPEN+M A
Sbjct: 471 PLMLQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAV 530
Query: 535 IDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQR 594
IDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVH+PQPSG+ LSLQ+AS P+ECSQR
Sbjct: 531 IDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQR 590
Query: 595 SAQELPHIEKYSINSCSVNGGHEMVVTGSNFLPESKIIFLEKGQDGRPQWEVEGKIIREK 654
SAQELP +EK S +S V GG +MV++G NFL +SK+IF+EK DG WE+E K R+
Sbjct: 591 SAQELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDL 650
Query: 655 CQGAHIVLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTP 699
C+ +V+E+PP+ N +T+ V V FY+CNGKRK+SQ QRFTY P
Sbjct: 651 CKPNSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLP 695
>gi|27886539 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 2 isoform B [Homo sapiens]
Length = 921
Score = 453 bits (1166), Expect = e-127
Identities = 344/895 (38%), Positives = 451/895 (50%), Gaps = 124/895 (13%)
Query: 10 DELDFKLVFGEDGAPAPPPPGSRPADLEPDDCASIYIFNVDPPPSTLTTPLCLPHHGLPS 69
DELDF ++F + P + EP+ V PPS P + +GL
Sbjct: 26 DELDFSILFDYEYL--------NPNEEEPN------AHKVASPPSGPAYPDDVLDYGLKP 71
Query: 70 HSSVLSPSFQLQSHKNYEGTCEIPESKYSPLGGPKPFEC----PSIQITSISPNCHQELD 125
+S + S S + + + K+ L KP P I+IT H+ +
Sbjct: 72 YSPLASLSGEPPGR--FGEPDRVGPQKF--LSAAKPAGASGLSPRIEITP----SHELIQ 123
Query: 126 A------HEDDLQINDPEREFLERPSRDHLYLPLEPSYRESSLSPSPASSISSRSWFSDA 179
A + L + P + R L +P YRE L SPASS SS S+ SD
Sbjct: 124 AVGPLRMRDAGLLVEQPPLAGVAASPRFTLPVPGFEGYREP-LCLSPASSGSSASFISDT 182
Query: 180 SSCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCPGEETWHQQYGLGHSLSPRQ 239
S P TSP SP ++ Q + SPR
Sbjct: 183 FS--------------------------PYTSPCVSPNNGGPDDLCPQFQNIPAHYSPRT 216
Query: 240 SPCHSPRSSVTDENWLSPR-PASGPSSRPTSPCGKRRHSSAEVCYAGSLSPHHSPVPSPG 298
SP SPR+S+ +++ L P P+SR +SP KRRHS AE A L P SP S
Sbjct: 217 SPIMSPRTSLAEDSCLGRHSPVPRPASRSSSPGAKRRHSCAEALVA--LPPGASPQRSRS 274
Query: 299 HSPRGSVTEDTWLNASVHGGSGLGPAVFPFQYCVETDIPLKTRKTSEDQAAILPGKLELC 358
SP+ S + + HG P V ++ L T D +P K+
Sbjct: 275 PSPQPS----SHVAPQDHGSPAGYPPVAGSAVIMDALNSLAT-----DSPCGIPPKMWKT 325
Query: 359 SDDQGSLSPARETSIDDGLGSQ-YPL-----------KKDSCGDQFLSVPSPFTWSKPKP 406
S D +S A + GL YP +++S + L VP TW KP
Sbjct: 326 SPDPSPVSAAPSKA---GLPRHIYPAVEFLGPCEQGERRNSAPESILLVPP--TWPKPLV 380
Query: 407 GHTPIFR---TSSLPPLDWPLPAHFGQCELKIEVQPKTHHRAHYETEGSRGAVKASTGGH 463
PI T+SLPPL+WPL + G EL+IEVQPK HHRAHYETEGSRGAVKA TGGH
Sbjct: 381 PAIPICSIPVTASLPPLEWPLSSQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTGGH 440
Query: 464 PVVKLLGYNE-KPINLQMFIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLE 522
PVV+L GY E KP+ LQ+FIGTAD+R L+PHAFYQVHRITGKTV T S E I+ +TKVLE
Sbjct: 441 PVVQLHGYMENKPLGLQIFIGTADERILKPHAFYQVHRITGKTVTTTSYEKIVGNTKVLE 500
Query: 523 IPLLPENNMSASIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSL 582
IPL P+NNM A+IDCAGILKLRN+DIELRKGETDIGRKNTRVRLVFRVHIP+ SG+++SL
Sbjct: 501 IPLEPKNNMRATIDCAGILKLRNADIELRKGETDIGRKNTRVRLVFRVHIPESSGRIVSL 560
Query: 583 QIASIPVECSQRSAQELPHIEKYSINSCSVNGGHEMVVTGSNFLPESKIIFLEKGQDGRP 642
Q AS P+ECSQRSA ELP +E+ +SC V GG +M++TG NF ESK++F EK DG+
Sbjct: 561 QTASNPIECSQRSAHELPMVERQDTDSCLVYGGQQMILTGQNFTSESKVVFTEKTTDGQQ 620
Query: 643 QWEVEGKIIREKCQGAHIVLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTPV-L 701
WE+E + ++K Q + +E+P Y N + V+V+FY+ NGKRK+SQ Q FTY PV
Sbjct: 621 IWEMEATVDKDKSQPNMLFVEIPEYRNKHIRTPVKVNFYVINGKRKRSQPQHFTYHPVPA 680
Query: 702 MKQEHREEID-----------LSSVPSLPVPHPAQTQRPSS-----------DSGCSHDS 739
+K E +E D L S P P HP + PS +G S
Sbjct: 681 IKTEPTDEYDPTLICSPTHGGLGSQPYYP-QHPMVAESPSCLVATMAPCQQFRTGLSSPD 739
Query: 740 VLSGQRSLICSIPQTYASMVTS---SHLPQLQCRDESVSKEQHMIPSPIVHQPFQVTPTP 796
Q++ + Q S+ S P L S++ S +VH Q +
Sbjct: 740 ARYQQQNPAAVLYQRSKSLSPSLLGYQQPALMAAPLSLADAHR---SVLVHAGSQGQSSA 796
Query: 797 PVGSSYQPMQTN-VVYNGPTCLPINAASSQEFDSVLFQQDATLSGLVNLGCQPLS 850
+ S Q + V++ PT + S QEF +++ ++ G G P+S
Sbjct: 797 LLHPSPTNQQASPVIHYSPTNQQLRCGSHQEFQHIMYCENFA-PGTTRPGPPPVS 850
>gi|27886541 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 2 isoform C [Homo sapiens]
Length = 925
Score = 453 bits (1166), Expect = e-127
Identities = 344/895 (38%), Positives = 451/895 (50%), Gaps = 124/895 (13%)
Query: 10 DELDFKLVFGEDGAPAPPPPGSRPADLEPDDCASIYIFNVDPPPSTLTTPLCLPHHGLPS 69
DELDF ++F + P + EP+ V PPS P + +GL
Sbjct: 26 DELDFSILFDYEYL--------NPNEEEPN------AHKVASPPSGPAYPDDVLDYGLKP 71
Query: 70 HSSVLSPSFQLQSHKNYEGTCEIPESKYSPLGGPKPFEC----PSIQITSISPNCHQELD 125
+S + S S + + + K+ L KP P I+IT H+ +
Sbjct: 72 YSPLASLSGEPPGR--FGEPDRVGPQKF--LSAAKPAGASGLSPRIEITP----SHELIQ 123
Query: 126 A------HEDDLQINDPEREFLERPSRDHLYLPLEPSYRESSLSPSPASSISSRSWFSDA 179
A + L + P + R L +P YRE L SPASS SS S+ SD
Sbjct: 124 AVGPLRMRDAGLLVEQPPLAGVAASPRFTLPVPGFEGYREP-LCLSPASSGSSASFISDT 182
Query: 180 SSCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCPGEETWHQQYGLGHSLSPRQ 239
S P TSP SP ++ Q + SPR
Sbjct: 183 FS--------------------------PYTSPCVSPNNGGPDDLCPQFQNIPAHYSPRT 216
Query: 240 SPCHSPRSSVTDENWLSPR-PASGPSSRPTSPCGKRRHSSAEVCYAGSLSPHHSPVPSPG 298
SP SPR+S+ +++ L P P+SR +SP KRRHS AE A L P SP S
Sbjct: 217 SPIMSPRTSLAEDSCLGRHSPVPRPASRSSSPGAKRRHSCAEALVA--LPPGASPQRSRS 274
Query: 299 HSPRGSVTEDTWLNASVHGGSGLGPAVFPFQYCVETDIPLKTRKTSEDQAAILPGKLELC 358
SP+ S + + HG P V ++ L T D +P K+
Sbjct: 275 PSPQPS----SHVAPQDHGSPAGYPPVAGSAVIMDALNSLAT-----DSPCGIPPKMWKT 325
Query: 359 SDDQGSLSPARETSIDDGLGSQ-YPL-----------KKDSCGDQFLSVPSPFTWSKPKP 406
S D +S A + GL YP +++S + L VP TW KP
Sbjct: 326 SPDPSPVSAAPSKA---GLPRHIYPAVEFLGPCEQGERRNSAPESILLVPP--TWPKPLV 380
Query: 407 GHTPIFR---TSSLPPLDWPLPAHFGQCELKIEVQPKTHHRAHYETEGSRGAVKASTGGH 463
PI T+SLPPL+WPL + G EL+IEVQPK HHRAHYETEGSRGAVKA TGGH
Sbjct: 381 PAIPICSIPVTASLPPLEWPLSSQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTGGH 440
Query: 464 PVVKLLGYNE-KPINLQMFIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLE 522
PVV+L GY E KP+ LQ+FIGTAD+R L+PHAFYQVHRITGKTV T S E I+ +TKVLE
Sbjct: 441 PVVQLHGYMENKPLGLQIFIGTADERILKPHAFYQVHRITGKTVTTTSYEKIVGNTKVLE 500
Query: 523 IPLLPENNMSASIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSL 582
IPL P+NNM A+IDCAGILKLRN+DIELRKGETDIGRKNTRVRLVFRVHIP+ SG+++SL
Sbjct: 501 IPLEPKNNMRATIDCAGILKLRNADIELRKGETDIGRKNTRVRLVFRVHIPESSGRIVSL 560
Query: 583 QIASIPVECSQRSAQELPHIEKYSINSCSVNGGHEMVVTGSNFLPESKIIFLEKGQDGRP 642
Q AS P+ECSQRSA ELP +E+ +SC V GG +M++TG NF ESK++F EK DG+
Sbjct: 561 QTASNPIECSQRSAHELPMVERQDTDSCLVYGGQQMILTGQNFTSESKVVFTEKTTDGQQ 620
Query: 643 QWEVEGKIIREKCQGAHIVLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTPV-L 701
WE+E + ++K Q + +E+P Y N + V+V+FY+ NGKRK+SQ Q FTY PV
Sbjct: 621 IWEMEATVDKDKSQPNMLFVEIPEYRNKHIRTPVKVNFYVINGKRKRSQPQHFTYHPVPA 680
Query: 702 MKQEHREEID-----------LSSVPSLPVPHPAQTQRPSS-----------DSGCSHDS 739
+K E +E D L S P P HP + PS +G S
Sbjct: 681 IKTEPTDEYDPTLICSPTHGGLGSQPYYP-QHPMVAESPSCLVATMAPCQQFRTGLSSPD 739
Query: 740 VLSGQRSLICSIPQTYASMVTS---SHLPQLQCRDESVSKEQHMIPSPIVHQPFQVTPTP 796
Q++ + Q S+ S P L S++ S +VH Q +
Sbjct: 740 ARYQQQNPAAVLYQRSKSLSPSLLGYQQPALMAAPLSLADAHR---SVLVHAGSQGQSSA 796
Query: 797 PVGSSYQPMQTN-VVYNGPTCLPINAASSQEFDSVLFQQDATLSGLVNLGCQPLS 850
+ S Q + V++ PT + S QEF +++ ++ G G P+S
Sbjct: 797 LLHPSPTNQQASPVIHYSPTNQQLRCGSHQEFQHIMYCENFA-PGTTRPGPPPVS 850
>gi|209862843 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 2 isoform D [Homo sapiens]
Length = 901
Score = 451 bits (1160), Expect = e-126
Identities = 315/764 (41%), Positives = 405/764 (53%), Gaps = 92/764 (12%)
Query: 131 LQINDPEREFLERPSRDHLYLPLEPSYRESSLSPSPASSISSRSWFSDASSCESLSHIYD 190
L + P + R L +P YRE L SPASS SS S+ SD S
Sbjct: 115 LLVEQPPLAGVAASPRFTLPVPGFEGYREP-LCLSPASSGSSASFISDTFS--------- 164
Query: 191 DVDSELNEAAARFTLGSPLTSPGGSPGGCPGEETWHQQYGLGHSLSPRQSPCHSPRSSVT 250
P TSP SP ++ Q + SPR SP SPR+S+
Sbjct: 165 -----------------PYTSPCVSPNNGGPDDLCPQFQNIPAHYSPRTSPIMSPRTSLA 207
Query: 251 DENWLSPR-PASGPSSRPTSPCGKRRHSSAEVCYAGSLSPHHSPVPSPGHSPRGSVTEDT 309
+++ L P P+SR +SP KRRHS AE A L P SP S SP+ S +
Sbjct: 208 EDSCLGRHSPVPRPASRSSSPGAKRRHSCAEALVA--LPPGASPQRSRSPSPQPS----S 261
Query: 310 WLNASVHGGSGLGPAVFPFQYCVETDIPLKTRKTSEDQAAILPGKLELCSDDQGSLSPAR 369
+ HG P V ++ L T D +P K+ S D +S A
Sbjct: 262 HVAPQDHGSPAGYPPVAGSAVIMDALNSLAT-----DSPCGIPPKMWKTSPDPSPVSAAP 316
Query: 370 ETSIDDGLGSQ-YPL-----------KKDSCGDQFLSVPSPFTWSKPKPGHTPIFR---T 414
+ GL YP +++S + L VP TW KP PI T
Sbjct: 317 SKA---GLPRHIYPAVEFLGPCEQGERRNSAPESILLVPP--TWPKPLVPAIPICSIPVT 371
Query: 415 SSLPPLDWPLPAHFGQCELKIEVQPKTHHRAHYETEGSRGAVKASTGGHPVVKLLGYNE- 473
+SLPPL+WPL + G EL+IEVQPK HHRAHYETEGSRGAVKA TGGHPVV+L GY E
Sbjct: 372 ASLPPLEWPLSSQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTGGHPVVQLHGYMEN 431
Query: 474 KPINLQMFIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLLPENNMSA 533
KP+ LQ+FIGTAD+R L+PHAFYQVHRITGKTV T S E I+ +TKVLEIPL P+NNM A
Sbjct: 432 KPLGLQIFIGTADERILKPHAFYQVHRITGKTVTTTSYEKIVGNTKVLEIPLEPKNNMRA 491
Query: 534 SIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQ 593
+IDCAGILKLRN+DIELRKGETDIGRKNTRVRLVFRVHIP+ SG+++SLQ AS P+ECSQ
Sbjct: 492 TIDCAGILKLRNADIELRKGETDIGRKNTRVRLVFRVHIPESSGRIVSLQTASNPIECSQ 551
Query: 594 RSAQELPHIEKYSINSCSVNGGHEMVVTGSNFLPESKIIFLEKGQDGRPQWEVEGKIIRE 653
RSA ELP +E+ +SC V GG +M++TG NF ESK++F EK DG+ WE+E + ++
Sbjct: 552 RSAHELPMVERQDTDSCLVYGGQQMILTGQNFTSESKVVFTEKTTDGQQIWEMEATVDKD 611
Query: 654 KCQGAHIVLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTPV-LMKQEHREEID- 711
K Q + +E+P Y N + V+V+FY+ NGKRK+SQ Q FTY PV +K E +E D
Sbjct: 612 KSQPNMLFVEIPEYRNKHIRTPVKVNFYVINGKRKRSQPQHFTYHPVPAIKTEPTDEYDP 671
Query: 712 ----------LSSVPSLPVPHPAQTQRPSS-----------DSGCSHDSVLSGQRSLICS 750
L S P P HP + PS +G S Q++
Sbjct: 672 TLICSPTHGGLGSQPYYP-QHPMVAESPSCLVATMAPCQQFRTGLSSPDARYQQQNPAAV 730
Query: 751 IPQTYASMVTS---SHLPQLQCRDESVSKEQHMIPSPIVHQPFQVTPTPPVGSSYQPMQT 807
+ Q S+ S P L S++ S +VH Q + + S Q
Sbjct: 731 LYQRSKSLSPSLLGYQQPALMAAPLSLADAHR---SVLVHAGSQGQSSALLHPSPTNQQA 787
Query: 808 N-VVYNGPTCLPINAASSQEFDSVLFQQDATLSGLVNLGCQPLS 850
+ V++ PT + S QEF +++ ++ G G P+S
Sbjct: 788 SPVIHYSPTNQQLRCGSHQEFQHIMYCENFA-PGTTRPGPPPVS 830
>gi|27502388 nuclear factor of activated T-cells, cytosolic
component 1 isoform D [Homo sapiens]
Length = 353
Score = 324 bits (831), Expect = 2e-88
Identities = 166/270 (61%), Positives = 204/270 (75%), Gaps = 12/270 (4%)
Query: 478 LQMFIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLLPENNMSASIDC 537
LQ+FIGTADDR LRPHAFYQVHRITGKTV+T S E I+++TKVLEIPLLPEN+M A IDC
Sbjct: 2 LQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDC 61
Query: 538 AGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQ 597
AGILKLRNSDIELRKGETDIGRKNTRVRLVFRVH+PQPSG+ LSLQ+AS P+ECSQRSAQ
Sbjct: 62 AGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRSAQ 121
Query: 598 ELPHIEKYSINSCSVNGGHEMVVTGSNFLPESKIIFLEKGQDGRPQWEVEGKIIREKCQG 657
ELP +EK S +S V GG +MV++G NFL +SK+IF+EK DG WE+E K R+ C+
Sbjct: 122 ELPLVEKQSTDSYPVVGGKKMVLSGHNFLQDSKVIFVEKAPDGHHVWEMEAKTDRDLCKP 181
Query: 658 AHIVLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTPV---LMKQEHREEIDLS- 713
+V+E+PP+ N +T+ V V FY+CNGKRK+SQ QRFTY P ++K E ++ + +
Sbjct: 182 NSLVVEIPPFRNQRITSPVHVSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDDYEPAP 241
Query: 714 -----SVPSLPVPHPAQTQR---PSSDSGC 735
S P+P P +Q+ P S C
Sbjct: 242 TCGPVSQGLSPLPRPYYSQQLAMPPDPSSC 271
>gi|5729945 nuclear factor of activated T-cells 5 isoform c [Homo
sapiens]
Length = 1531
Score = 226 bits (575), Expect = 1e-58
Identities = 204/689 (29%), Positives = 307/689 (44%), Gaps = 76/689 (11%)
Query: 166 PASSISSRSWFSDASSCESL---SHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCPGE 222
P+ IS S D S +SL +YD + EL +R T + ++ G G P
Sbjct: 2 PSDFISLLSADLDLESPKSLYSRESVYDLLPKELQLPPSRETSVASMSQTSGGEAGSPPP 61
Query: 223 ETWHQQYGLGHSLSPRQSPCHS---------PRSSVTDENWLSPRPASGPSSRPTSPCGK 273
S S C S +SVTD + S +
Sbjct: 62 AVVAADASSAPSSSSMGGACSSFTTSSSPTIYSTSVTDSKAMQVESCSSAVGVSNRGVSE 121
Query: 274 RRHSSAEVCYAGSLSPHH-----SPVPSP------------GHSPRGSVTEDTWLNASVH 316
++ +S V S H SP P G + W+ S
Sbjct: 122 KQLTSNTVQQHPSTPKRHTVLYISPPPEDLLDNSRMSCQDEGCGLESEQSCSMWMEDSPS 181
Query: 317 GGSGLGPAVFPFQYCVETDIPLKTRKTSEDQAAILPG-KLELCSDDQGSLSPARETSIDD 375
S + + Y T++P K+RK + Q PG K C + + A D
Sbjct: 182 NFSNMSTS----SYNDNTEVPRKSRKRNPKQR---PGVKRRDCEESNMDIFDA-----DS 229
Query: 376 GLGSQYPLKKDSCGDQFLSVPSPFTWSKPKPGHTPIFRTSSLPPLDWPLPAHFGQCELKI 435
Y L + + ++ S T K T + ++ P L P ELKI
Sbjct: 230 AKAPHYVLSQLTTDNKGNSKAGNGTLENQKG--TGVKKS---PMLCGQYPVKSEGKELKI 284
Query: 436 EVQPKTHHRAHYETEGSRGAVKASTG-GHPVVKLLGYNEKPINLQMFIGTADDRYLRPHA 494
VQP+T HRA Y TEGSRG+VK T G P VKL G+NE P+ LQ+F+G R ++PH
Sbjct: 285 VVQPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGHNE-PVVLQVFVGNDSGR-VKPHG 342
Query: 495 FYQVHRITGKTVATASQEIIIASTKVLEIPLLPENNMSASIDCAGILKLRNSDIELRKGE 554
FYQ R+TG+ T +E+ I T V+E+ L P NNM+ ++DC GILKLRN+D+E R G
Sbjct: 343 FYQACRVTGRNT-TPCKEVDIEGTTVIEVGLDPSNNMTLAVDCVGILKLRNADVEARIGI 401
Query: 555 TDIGRKNTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELPHIEKYSINSCSVNG 614
+K+TR RLVFRV+I + G L+LQ S P+ C+Q + +P I K S++SCSV G
Sbjct: 402 AGSKKKSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPAG--VPEILKKSLHSCSVKG 459
Query: 615 GHEMVVTGSNFLPESKIIFLEKGQDGRPQWEVEGKIIREKCQGAHIVLEVPPYHNPAVTA 674
E+ + G NFL +K+IF E D W+ E +I E H++++VPPYH+ +T
Sbjct: 460 EEEVFLIGKNFLKGTKVIFQENVSD-ENSWKSEAEIDMELFHQNHLIVKVPPYHDQHITL 518
Query: 675 AVQVHFYLCNGKRKKSQSQRFTYTPVLMKQEHREEIDLSSVPSLPVPHPAQTQRPSSDSG 734
V V Y+ + Q FTYTP D ++ +L V + P+
Sbjct: 519 PVSVGIYVVTNAGRSHDVQPFTYTP-----------DPAAAGALNVNVKKEISSPARP-- 565
Query: 735 CSHDSVLSGQRSLICSIPQTYASMVTSSHLPQLQCRDESVSKEQHMIPSPIVHQPFQVT- 793
CS + + ++ C++ + +++ ++ + L S+ K + + P + + T
Sbjct: 566 CSFEEAMKAMKTTGCNLDK--VNIIPNALMTPL--IPSSMIKSEDVTPMEVTAEKRSSTI 621
Query: 794 --PTPPVGSSYQPMQ--TNVVYNGPTCLP 818
T VGS+ Q ++ +N+ NG P
Sbjct: 622 FKTTKSVGSTQQTLENISNIAGNGSFSSP 650
Score = 43.1 bits (100), Expect = 0.001
Identities = 85/407 (20%), Positives = 148/407 (36%), Gaps = 68/407 (16%)
Query: 646 VEGKIIREKCQGAHIVLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTPVLMKQE 705
++G + + Q +I L P +N Q F+ QS + +Q+
Sbjct: 1126 LQGSSVPQDQQSTNIFLSQSPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQ 1185
Query: 706 HREEIDLSSVPSLPVPHPAQTQRPSSDSGCSHDSVLSG----------QRSLICSIPQTY 755
+ + + P +Q Q G V G Q+ + +
Sbjct: 1186 -------APISHIQTPMLSQEQAQPPQQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSI 1238
Query: 756 ASMVTSSHLPQLQCRDESVSKEQHMIPSPIVHQPFQVTPTPPVGSSYQPMQTNVVYNGPT 815
+M ++S + Q + + ++Q I+ T + S QP N+++N P
Sbjct: 1239 VAMQSNSPSQEQQQQQQQQQQQQQQQQQSILFSNQNTMAT--MASPKQP-PPNMIFN-PN 1294
Query: 816 CLPINAASSQEFDSVLFQQDATLSGLVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHSVHT 875
P+ A+ ++ + +F Q + ++ + N QP+ F S + T
Sbjct: 1295 QNPM--ANQEQQNQSIFHQQSNMAPM-NQEQQPMQ---FQSQS----------------T 1332
Query: 876 LPHLQSMGYHCSNTGQRSL--SSPVADQITGQPSSQLQPITYGPSHSGSATTASPAASHP 933
+ LQ+ G S + Q L SSP + G PSSQ Q +T S + + +
Sbjct: 1333 VSSLQNPGPTQSESSQTPLFHSSPQIQLVQGSPSSQEQQVTLFLSPASMSALQTSINQQD 1392
Query: 934 LASSPLSGPPS--PQLQPMPYQSPSSGTASSPSP-ATRMHSGQHSTQAQSTGQGGLSAPS 990
+ SPL P + P +Q G SSP P AT H+ T Q G S +
Sbjct: 1393 MQQSPLYSPQNNMPGIQ---------GATSSPQPQATLFHNTAGGTMNQLQNSPGSSQQT 1443
Query: 991 SLI--------CHSL--CDPASFPPDGATVSIKPEPEDR-EPNFATI 1026
S + C L PA+ P +S +P++ +P T+
Sbjct: 1444 SGMFLFGIQNNCSQLLTSGPATLPDQLMAISQPGQPQNEGQPPVTTL 1490
>gi|27886520 nuclear factor of activated T-cells 5 isoform a [Homo
sapiens]
Length = 1455
Score = 225 bits (573), Expect = 2e-58
Identities = 145/393 (36%), Positives = 217/393 (55%), Gaps = 29/393 (7%)
Query: 432 ELKIEVQPKTHHRAHYETEGSRGAVKASTG-GHPVVKLLGYNEKPINLQMFIGTADDRYL 490
ELKI VQP+T HRA Y TEGSRG+VK T G P VKL G+NE P+ LQ+F+G R +
Sbjct: 205 ELKIVVQPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGHNE-PVVLQVFVGNDSGR-V 262
Query: 491 RPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLLPENNMSASIDCAGILKLRNSDIEL 550
+PH FYQ R+TG+ T +E+ I T V+E+ L P NNM+ ++DC GILKLRN+D+E
Sbjct: 263 KPHGFYQACRVTGRNT-TPCKEVDIEGTTVIEVGLDPSNNMTLAVDCVGILKLRNADVEA 321
Query: 551 RKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELPHIEKYSINSC 610
R G +K+TR RLVFRV+I + G L+LQ S P+ C+Q + +P I K S++SC
Sbjct: 322 RIGIAGSKKKSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPAG--VPEILKKSLHSC 379
Query: 611 SVNGGHEMVVTGSNFLPESKIIFLEKGQDGRPQWEVEGKIIREKCQGAHIVLEVPPYHNP 670
SV G E+ + G NFL +K+IF E D W+ E +I E H++++VPPYH+
Sbjct: 380 SVKGEEEVFLIGKNFLKGTKVIFQENVSD-ENSWKSEAEIDMELFHQNHLIVKVPPYHDQ 438
Query: 671 AVTAAVQVHFYLCNGKRKKSQSQRFTYTPVLMKQEHREEIDLSSVPSLPVPHPAQTQRPS 730
+T V V Y+ + Q FTYTP D ++ +L V + P+
Sbjct: 439 HITLPVSVGIYVVTNAGRSHDVQPFTYTP-----------DPAAAGALNVNVKKEISSPA 487
Query: 731 SDSGCSHDSVLSGQRSLICSIPQTYASMVTSSHLPQLQCRDESVSKEQHMIPSPIVHQPF 790
CS + + ++ C++ + +++ ++ + L S+ K + + P + +
Sbjct: 488 RP--CSFEEAMKAMKTTGCNLDK--VNIIPNALMTPL--IPSSMIKSEDVTPMEVTAEKR 541
Query: 791 QVT---PTPPVGSSYQPMQ--TNVVYNGPTCLP 818
T T VGS+ Q ++ +N+ NG P
Sbjct: 542 SSTIFKTTKSVGSTQQTLENISNIAGNGSFSSP 574
Score = 43.1 bits (100), Expect = 0.001
Identities = 85/407 (20%), Positives = 148/407 (36%), Gaps = 68/407 (16%)
Query: 646 VEGKIIREKCQGAHIVLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTPVLMKQE 705
++G + + Q +I L P +N Q F+ QS + +Q+
Sbjct: 1050 LQGSSVPQDQQSTNIFLSQSPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQ 1109
Query: 706 HREEIDLSSVPSLPVPHPAQTQRPSSDSGCSHDSVLSG----------QRSLICSIPQTY 755
+ + + P +Q Q G V G Q+ + +
Sbjct: 1110 -------APISHIQTPMLSQEQAQPPQQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSI 1162
Query: 756 ASMVTSSHLPQLQCRDESVSKEQHMIPSPIVHQPFQVTPTPPVGSSYQPMQTNVVYNGPT 815
+M ++S + Q + + ++Q I+ T + S QP N+++N P
Sbjct: 1163 VAMQSNSPSQEQQQQQQQQQQQQQQQQQSILFSNQNTMAT--MASPKQP-PPNMIFN-PN 1218
Query: 816 CLPINAASSQEFDSVLFQQDATLSGLVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHSVHT 875
P+ A+ ++ + +F Q + ++ + N QP+ F S + T
Sbjct: 1219 QNPM--ANQEQQNQSIFHQQSNMAPM-NQEQQPMQ---FQSQS----------------T 1256
Query: 876 LPHLQSMGYHCSNTGQRSL--SSPVADQITGQPSSQLQPITYGPSHSGSATTASPAASHP 933
+ LQ+ G S + Q L SSP + G PSSQ Q +T S + + +
Sbjct: 1257 VSSLQNPGPTQSESSQTPLFHSSPQIQLVQGSPSSQEQQVTLFLSPASMSALQTSINQQD 1316
Query: 934 LASSPLSGPPS--PQLQPMPYQSPSSGTASSPSP-ATRMHSGQHSTQAQSTGQGGLSAPS 990
+ SPL P + P +Q G SSP P AT H+ T Q G S +
Sbjct: 1317 MQQSPLYSPQNNMPGIQ---------GATSSPQPQATLFHNTAGGTMNQLQNSPGSSQQT 1367
Query: 991 SLI--------CHSL--CDPASFPPDGATVSIKPEPEDR-EPNFATI 1026
S + C L PA+ P +S +P++ +P T+
Sbjct: 1368 SGMFLFGIQNNCSQLLTSGPATLPDQLMAISQPGQPQNEGQPPVTTL 1414
>gi|164419744 nuclear factor of activated T-cells 5 isoform b [Homo
sapiens]
Length = 1549
Score = 225 bits (573), Expect = 2e-58
Identities = 145/393 (36%), Positives = 217/393 (55%), Gaps = 29/393 (7%)
Query: 432 ELKIEVQPKTHHRAHYETEGSRGAVKASTG-GHPVVKLLGYNEKPINLQMFIGTADDRYL 490
ELKI VQP+T HRA Y TEGSRG+VK T G P VKL G+NE P+ LQ+F+G R +
Sbjct: 299 ELKIVVQPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGHNE-PVVLQVFVGNDSGR-V 356
Query: 491 RPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLLPENNMSASIDCAGILKLRNSDIEL 550
+PH FYQ R+TG+ T +E+ I T V+E+ L P NNM+ ++DC GILKLRN+D+E
Sbjct: 357 KPHGFYQACRVTGRNT-TPCKEVDIEGTTVIEVGLDPSNNMTLAVDCVGILKLRNADVEA 415
Query: 551 RKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELPHIEKYSINSC 610
R G +K+TR RLVFRV+I + G L+LQ S P+ C+Q + +P I K S++SC
Sbjct: 416 RIGIAGSKKKSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPAG--VPEILKKSLHSC 473
Query: 611 SVNGGHEMVVTGSNFLPESKIIFLEKGQDGRPQWEVEGKIIREKCQGAHIVLEVPPYHNP 670
SV G E+ + G NFL +K+IF E D W+ E +I E H++++VPPYH+
Sbjct: 474 SVKGEEEVFLIGKNFLKGTKVIFQENVSD-ENSWKSEAEIDMELFHQNHLIVKVPPYHDQ 532
Query: 671 AVTAAVQVHFYLCNGKRKKSQSQRFTYTPVLMKQEHREEIDLSSVPSLPVPHPAQTQRPS 730
+T V V Y+ + Q FTYTP D ++ +L V + P+
Sbjct: 533 HITLPVSVGIYVVTNAGRSHDVQPFTYTP-----------DPAAAGALNVNVKKEISSPA 581
Query: 731 SDSGCSHDSVLSGQRSLICSIPQTYASMVTSSHLPQLQCRDESVSKEQHMIPSPIVHQPF 790
CS + + ++ C++ + +++ ++ + L S+ K + + P + +
Sbjct: 582 RP--CSFEEAMKAMKTTGCNLDK--VNIIPNALMTPL--IPSSMIKSEDVTPMEVTAEKR 635
Query: 791 QVT---PTPPVGSSYQPMQ--TNVVYNGPTCLP 818
T T VGS+ Q ++ +N+ NG P
Sbjct: 636 SSTIFKTTKSVGSTQQTLENISNIAGNGSFSSP 668
Score = 43.1 bits (100), Expect = 0.001
Identities = 85/407 (20%), Positives = 148/407 (36%), Gaps = 68/407 (16%)
Query: 646 VEGKIIREKCQGAHIVLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTPVLMKQE 705
++G + + Q +I L P +N Q F+ QS + +Q+
Sbjct: 1144 LQGSSVPQDQQSTNIFLSQSPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQ 1203
Query: 706 HREEIDLSSVPSLPVPHPAQTQRPSSDSGCSHDSVLSG----------QRSLICSIPQTY 755
+ + + P +Q Q G V G Q+ + +
Sbjct: 1204 -------APISHIQTPMLSQEQAQPPQQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSI 1256
Query: 756 ASMVTSSHLPQLQCRDESVSKEQHMIPSPIVHQPFQVTPTPPVGSSYQPMQTNVVYNGPT 815
+M ++S + Q + + ++Q I+ T + S QP N+++N P
Sbjct: 1257 VAMQSNSPSQEQQQQQQQQQQQQQQQQQSILFSNQNTMAT--MASPKQP-PPNMIFN-PN 1312
Query: 816 CLPINAASSQEFDSVLFQQDATLSGLVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHSVHT 875
P+ A+ ++ + +F Q + ++ + N QP+ F S + T
Sbjct: 1313 QNPM--ANQEQQNQSIFHQQSNMAPM-NQEQQPMQ---FQSQS----------------T 1350
Query: 876 LPHLQSMGYHCSNTGQRSL--SSPVADQITGQPSSQLQPITYGPSHSGSATTASPAASHP 933
+ LQ+ G S + Q L SSP + G PSSQ Q +T S + + +
Sbjct: 1351 VSSLQNPGPTQSESSQTPLFHSSPQIQLVQGSPSSQEQQVTLFLSPASMSALQTSINQQD 1410
Query: 934 LASSPLSGPPS--PQLQPMPYQSPSSGTASSPSP-ATRMHSGQHSTQAQSTGQGGLSAPS 990
+ SPL P + P +Q G SSP P AT H+ T Q G S +
Sbjct: 1411 MQQSPLYSPQNNMPGIQ---------GATSSPQPQATLFHNTAGGTMNQLQNSPGSSQQT 1461
Query: 991 SLI--------CHSL--CDPASFPPDGATVSIKPEPEDR-EPNFATI 1026
S + C L PA+ P +S +P++ +P T+
Sbjct: 1462 SGMFLFGIQNNCSQLLTSGPATLPDQLMAISQPGQPQNEGQPPVTTL 1508
>gi|27886524 nuclear factor of activated T-cells 5 isoform a [Homo
sapiens]
Length = 1455
Score = 225 bits (573), Expect = 2e-58
Identities = 145/393 (36%), Positives = 217/393 (55%), Gaps = 29/393 (7%)
Query: 432 ELKIEVQPKTHHRAHYETEGSRGAVKASTG-GHPVVKLLGYNEKPINLQMFIGTADDRYL 490
ELKI VQP+T HRA Y TEGSRG+VK T G P VKL G+NE P+ LQ+F+G R +
Sbjct: 205 ELKIVVQPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGHNE-PVVLQVFVGNDSGR-V 262
Query: 491 RPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLLPENNMSASIDCAGILKLRNSDIEL 550
+PH FYQ R+TG+ T +E+ I T V+E+ L P NNM+ ++DC GILKLRN+D+E
Sbjct: 263 KPHGFYQACRVTGRNT-TPCKEVDIEGTTVIEVGLDPSNNMTLAVDCVGILKLRNADVEA 321
Query: 551 RKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELPHIEKYSINSC 610
R G +K+TR RLVFRV+I + G L+LQ S P+ C+Q + +P I K S++SC
Sbjct: 322 RIGIAGSKKKSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPAG--VPEILKKSLHSC 379
Query: 611 SVNGGHEMVVTGSNFLPESKIIFLEKGQDGRPQWEVEGKIIREKCQGAHIVLEVPPYHNP 670
SV G E+ + G NFL +K+IF E D W+ E +I E H++++VPPYH+
Sbjct: 380 SVKGEEEVFLIGKNFLKGTKVIFQENVSD-ENSWKSEAEIDMELFHQNHLIVKVPPYHDQ 438
Query: 671 AVTAAVQVHFYLCNGKRKKSQSQRFTYTPVLMKQEHREEIDLSSVPSLPVPHPAQTQRPS 730
+T V V Y+ + Q FTYTP D ++ +L V + P+
Sbjct: 439 HITLPVSVGIYVVTNAGRSHDVQPFTYTP-----------DPAAAGALNVNVKKEISSPA 487
Query: 731 SDSGCSHDSVLSGQRSLICSIPQTYASMVTSSHLPQLQCRDESVSKEQHMIPSPIVHQPF 790
CS + + ++ C++ + +++ ++ + L S+ K + + P + +
Sbjct: 488 RP--CSFEEAMKAMKTTGCNLDK--VNIIPNALMTPL--IPSSMIKSEDVTPMEVTAEKR 541
Query: 791 QVT---PTPPVGSSYQPMQ--TNVVYNGPTCLP 818
T T VGS+ Q ++ +N+ NG P
Sbjct: 542 SSTIFKTTKSVGSTQQTLENISNIAGNGSFSSP 574
Score = 43.1 bits (100), Expect = 0.001
Identities = 85/407 (20%), Positives = 148/407 (36%), Gaps = 68/407 (16%)
Query: 646 VEGKIIREKCQGAHIVLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTPVLMKQE 705
++G + + Q +I L P +N Q F+ QS + +Q+
Sbjct: 1050 LQGSSVPQDQQSTNIFLSQSPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQ 1109
Query: 706 HREEIDLSSVPSLPVPHPAQTQRPSSDSGCSHDSVLSG----------QRSLICSIPQTY 755
+ + + P +Q Q G V G Q+ + +
Sbjct: 1110 -------APISHIQTPMLSQEQAQPPQQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSI 1162
Query: 756 ASMVTSSHLPQLQCRDESVSKEQHMIPSPIVHQPFQVTPTPPVGSSYQPMQTNVVYNGPT 815
+M ++S + Q + + ++Q I+ T + S QP N+++N P
Sbjct: 1163 VAMQSNSPSQEQQQQQQQQQQQQQQQQQSILFSNQNTMAT--MASPKQP-PPNMIFN-PN 1218
Query: 816 CLPINAASSQEFDSVLFQQDATLSGLVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHSVHT 875
P+ A+ ++ + +F Q + ++ + N QP+ F S + T
Sbjct: 1219 QNPM--ANQEQQNQSIFHQQSNMAPM-NQEQQPMQ---FQSQS----------------T 1256
Query: 876 LPHLQSMGYHCSNTGQRSL--SSPVADQITGQPSSQLQPITYGPSHSGSATTASPAASHP 933
+ LQ+ G S + Q L SSP + G PSSQ Q +T S + + +
Sbjct: 1257 VSSLQNPGPTQSESSQTPLFHSSPQIQLVQGSPSSQEQQVTLFLSPASMSALQTSINQQD 1316
Query: 934 LASSPLSGPPS--PQLQPMPYQSPSSGTASSPSP-ATRMHSGQHSTQAQSTGQGGLSAPS 990
+ SPL P + P +Q G SSP P AT H+ T Q G S +
Sbjct: 1317 MQQSPLYSPQNNMPGIQ---------GATSSPQPQATLFHNTAGGTMNQLQNSPGSSQQT 1367
Query: 991 SLI--------CHSL--CDPASFPPDGATVSIKPEPEDR-EPNFATI 1026
S + C L PA+ P +S +P++ +P T+
Sbjct: 1368 SGMFLFGIQNNCSQLLTSGPATLPDQLMAISQPGQPQNEGQPPVTTL 1414
>gi|164419746 nuclear factor of activated T-cells 5 isoform d [Homo
sapiens]
Length = 1548
Score = 223 bits (568), Expect = 7e-58
Identities = 150/394 (38%), Positives = 216/394 (54%), Gaps = 32/394 (8%)
Query: 432 ELKIEVQPKTHHRAHYETEGSRGAVKASTG-GHPVVKLLGYNEKPINLQMFIGTADDRYL 490
ELKI VQP+T HRA Y TEGSRG+VK T G P VKL G+NE P+ LQ+F+G R +
Sbjct: 299 ELKIVVQPETQHRARYLTEGSRGSVKDRTQQGFPTVKLEGHNE-PVVLQVFVGNDSGR-V 356
Query: 491 RPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLLPENNMSASIDCAGILKLRNSDIEL 550
+PH FYQ R+TG+ T +E+ I T V+E+ L P NNM+ ++DC GILKLRN+D+E
Sbjct: 357 KPHGFYQACRVTGRNT-TPCKEVDIEGTTVIEVGLDPSNNMTLAVDCVGILKLRNADVEA 415
Query: 551 RKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELPHIEKYSINSC 610
R G +K+TR RLVFRV+I + G L+LQ S P+ C+Q + +P I K S++SC
Sbjct: 416 RIGIAGSKKKSTRARLVFRVNIMRKDGSTLTLQTPSSPILCTQPAG--VPEILKKSLHSC 473
Query: 611 SVNGGHEMVVTGSNFLPESKIIFLEKGQDGRPQWEVEGKIIREKCQGAHIVLEVPPYHNP 670
SV G E+ + G NFL +K+IF E D W+ E +I E H++++VPPYH+
Sbjct: 474 SVKGEEEVFLIGKNFLKGTKVIFQENVSD-ENSWKSEAEIDMELFHQNHLIVKVPPYHDQ 532
Query: 671 AVTAAVQVHFYLCNGKRKKSQSQRFTYTP----VLMKQEHREEIDLSSVPSLPVPHPAQT 726
+T V V Y+ + Q FTYTP + ++EI S P+ P +
Sbjct: 533 HITLPVSVGIYVVTNAGRSHDVQPFTYTPDPAAGALNVNVKKEI---SSPARPCSF-EEA 588
Query: 727 QRPSSDSGCSHDSVLSGQRSLICSIPQTYASMVTSSHLPQLQCRDESVSKEQHMIPSPIV 786
+ +GC+ D V +L+ P +SM+ S + ++ E S
Sbjct: 589 MKAMKTTGCNLDKVNIIPNALM--TPLIPSSMIKSEDVTPMEVTAEKRSS---------- 636
Query: 787 HQPFQVTPTPPVGSSYQPMQ--TNVVYNGPTCLP 818
F+ T + VGS+ Q ++ +N+ NG P
Sbjct: 637 -TIFKTTKS--VGSTQQTLENISNIAGNGSFSSP 667
Score = 43.1 bits (100), Expect = 0.001
Identities = 85/407 (20%), Positives = 148/407 (36%), Gaps = 68/407 (16%)
Query: 646 VEGKIIREKCQGAHIVLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTPVLMKQE 705
++G + + Q +I L P +N Q F+ QS + +Q+
Sbjct: 1143 LQGSSVPQDQQSTNIFLSQSPMNNLQTNTVAQEAFFAAPNSISPLQSTSNSEQQAAFQQQ 1202
Query: 706 HREEIDLSSVPSLPVPHPAQTQRPSSDSGCSHDSVLSG----------QRSLICSIPQTY 755
+ + + P +Q Q G V G Q+ + +
Sbjct: 1203 -------APISHIQTPMLSQEQAQPPQQGLFQPQVALGSLPPNPMPQSQQGTMFQSQHSI 1255
Query: 756 ASMVTSSHLPQLQCRDESVSKEQHMIPSPIVHQPFQVTPTPPVGSSYQPMQTNVVYNGPT 815
+M ++S + Q + + ++Q I+ T + S QP N+++N P
Sbjct: 1256 VAMQSNSPSQEQQQQQQQQQQQQQQQQQSILFSNQNTMAT--MASPKQP-PPNMIFN-PN 1311
Query: 816 CLPINAASSQEFDSVLFQQDATLSGLVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHSVHT 875
P+ A+ ++ + +F Q + ++ + N QP+ F S + T
Sbjct: 1312 QNPM--ANQEQQNQSIFHQQSNMAPM-NQEQQPMQ---FQSQS----------------T 1349
Query: 876 LPHLQSMGYHCSNTGQRSL--SSPVADQITGQPSSQLQPITYGPSHSGSATTASPAASHP 933
+ LQ+ G S + Q L SSP + G PSSQ Q +T S + + +
Sbjct: 1350 VSSLQNPGPTQSESSQTPLFHSSPQIQLVQGSPSSQEQQVTLFLSPASMSALQTSINQQD 1409
Query: 934 LASSPLSGPPS--PQLQPMPYQSPSSGTASSPSP-ATRMHSGQHSTQAQSTGQGGLSAPS 990
+ SPL P + P +Q G SSP P AT H+ T Q G S +
Sbjct: 1410 MQQSPLYSPQNNMPGIQ---------GATSSPQPQATLFHNTAGGTMNQLQNSPGSSQQT 1460
Query: 991 SLI--------CHSL--CDPASFPPDGATVSIKPEPEDR-EPNFATI 1026
S + C L PA+ P +S +P++ +P T+
Sbjct: 1461 SGMFLFGIQNNCSQLLTSGPATLPDQLMAISQPGQPQNEGQPPVTTL 1507
>gi|223468681 v-rel reticuloendotheliosis viral oncogene homolog A
isoform 2 [Homo sapiens]
Length = 548
Score = 61.6 bits (148), Expect = 4e-09
Identities = 102/428 (23%), Positives = 166/428 (38%), Gaps = 47/428 (10%)
Query: 419 PLDWPL-PAHFGQCELKIEVQPKTHH-RAHYETEG-SRGAVKA-----STGGHPVVKLLG 470
PL +P PA ++I QPK R Y+ EG S G++ +T HP +K+ G
Sbjct: 6 PLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKING 65
Query: 471 YNEKPINLQMFIGTADDRYLRPHAFYQVHRITGKTVATASQEI------IIASTKVLEIP 524
Y P +++ + T D + RPH H + GK E I S + L I
Sbjct: 66 YTG-PGTVRISLVTKDPPH-RPHP----HELVGKDCRDGFYEAELCPDRCIHSFQNLGIQ 119
Query: 525 LLPENNMSASIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSL-Q 583
+ + ++ +I I N E ++G+ D+ VRL F+V + PSG+ L L
Sbjct: 120 CVKKRDLEQAIS-QRIQTNNNPFQEEQRGDYDLNA----VRLCFQVTVRDPSGRPLRLPP 174
Query: 584 IASIPVECSQRSAQELPHIEKYSINSCSVNGGHEMVVTGSNFLPESKIIFLEKGQDGRPQ 643
+ S P+ ++ I + + NS S GG E+ + E ++ P
Sbjct: 175 VLSHPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFT-----GPG 229
Query: 644 WEVEGKIIR-EKCQGAHIVLEVPPYHNPAVTAAVQVHFYLCN-GKRKKSQSQRFTYTP-- 699
WE G + + + IV PPY +P++ A V+V L R+ S+ F Y P
Sbjct: 230 WEARGSFSQADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDT 289
Query: 700 -----VLMKQEHREEIDLSSVPSLPVPHPAQTQRPSSDSGCSHDSVLSGQRSLICSIPQT 754
+ K++ E S + P P + P S S + P T
Sbjct: 290 DDRHRIEEKRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFT 349
Query: 755 YA-SMVTSSHLPQLQCRDESVSKEQHMIPSPIVHQPFQVTPTPPVGSSYQPMQTNVVYNG 813
+ S + P + +S+ + P+P P P P P + +
Sbjct: 350 SSLSTINYDEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAP------APAMVSALAQA 403
Query: 814 PTCLPINA 821
P +P+ A
Sbjct: 404 PAPVPVLA 411
Score = 30.4 bits (67), Expect = 9.3
Identities = 14/33 (42%), Positives = 17/33 (51%)
Query: 934 LASSPLSGPPSPQLQPMPYQSPSSGTASSPSPA 966
+ SP SGP P+ P PS +AS P PA
Sbjct: 310 MKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPA 342
>gi|223468676 v-rel reticuloendotheliosis viral oncogene homolog A
isoform 1 [Homo sapiens]
Length = 551
Score = 60.8 bits (146), Expect = 6e-09
Identities = 102/432 (23%), Positives = 169/432 (39%), Gaps = 52/432 (12%)
Query: 419 PLDWPL-PAHFGQCELKIEVQPKTHH-RAHYETEG-SRGAVKA-----STGGHPVVKLLG 470
PL +P PA ++I QPK R Y+ EG S G++ +T HP +K+ G
Sbjct: 6 PLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKING 65
Query: 471 YNEKPINLQMFIGTADDRYLRPHAFYQVHRITGKTVATASQEI------IIASTKVLEIP 524
Y P +++ + T D + RPH H + GK E I S + L I
Sbjct: 66 YTG-PGTVRISLVTKDPPH-RPHP----HELVGKDCRDGFYEAELCPDRCIHSFQNLGIQ 119
Query: 525 LLPENNMSASIDCAGILKLRNSD----IELRKGETDIGRKNTRVRLVFRVHIPQPSGKVL 580
+ + ++ +I ++ N+ IE ++G+ D+ VRL F+V + PSG+ L
Sbjct: 120 CVKKRDLEQAISQR--IQTNNNPFQVPIEEQRGDYDLNA----VRLCFQVTVRDPSGRPL 173
Query: 581 SL-QIASIPVECSQRSAQELPHIEKYSINSCSVNGGHEMVVTGSNFLPESKIIFLEKGQD 639
L + S P+ ++ I + + NS S GG E+ + E ++
Sbjct: 174 RLPPVLSHPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFT---- 229
Query: 640 GRPQWEVEGKIIR-EKCQGAHIVLEVPPYHNPAVTAAVQVHFYLCN-GKRKKSQSQRFTY 697
P WE G + + + IV PPY +P++ A V+V L R+ S+ F Y
Sbjct: 230 -GPGWEARGSFSQADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQY 288
Query: 698 TP-------VLMKQEHREEIDLSSVPSLPVPHPAQTQRPSSDSGCSHDSVLSGQRSLICS 750
P + K++ E S + P P + P S S +
Sbjct: 289 LPDTDDRHRIEEKRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQP 348
Query: 751 IPQTYA-SMVTSSHLPQLQCRDESVSKEQHMIPSPIVHQPFQVTPTPPVGSSYQPMQTNV 809
P T + S + P + +S+ + P+P P P P P +
Sbjct: 349 YPFTSSLSTINYDEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAP------APAMVSA 402
Query: 810 VYNGPTCLPINA 821
+ P +P+ A
Sbjct: 403 LAQAPAPVPVLA 414
Score = 30.4 bits (67), Expect = 9.3
Identities = 14/33 (42%), Positives = 17/33 (51%)
Query: 934 LASSPLSGPPSPQLQPMPYQSPSSGTASSPSPA 966
+ SP SGP P+ P PS +AS P PA
Sbjct: 313 MKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPA 345
>gi|167736355 mucin 4 isoform a [Homo sapiens]
Length = 5284
Score = 55.1 bits (131), Expect = 4e-07
Identities = 83/355 (23%), Positives = 126/355 (35%), Gaps = 37/355 (10%)
Query: 714 SVPSLPVPHPAQTQRPSSDSGCSHDSVLSGQRSLICSIPQTYASMVTSSHLPQLQCRDES 773
S+ S + P S SG S + + S +P TYAS ++ H L D S
Sbjct: 941 SITSTGLTSPQTETHTLSPSG-SGKTFTTALISNATPLPVTYASSASTGHTTPLHVTDAS 999
Query: 774 VSKEQHMIPSPIVHQPFQV-----TPTPPVGSSYQ------PMQ----TNVVYNGPTCLP 818
H P P+ P V TP P +S + P+ ++ T LP
Sbjct: 1000 SVSTGHATPLPVT-SPSSVSTGHTTPLPVTDTSSESTGHVTPLPVTSFSSASTGDSTPLP 1058
Query: 819 INAASSQEFDSVLFQQDATLSGLVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHSVHTLPH 878
+ SS V +LS PL P ++S STGH + ++
Sbjct: 1059 VTDTSSASTGHVTPLPVTSLSSASTGDTTPL---PVTDTSSASTGHATSLPVTDTSSV-- 1113
Query: 879 LQSMGYHCSNTGQRSLSSPVADQITGQPSSQLQPITYG---PSHSGSATTASPAASHPLA 935
S G H + SS T P + ++ G P H A++AS + PL
Sbjct: 1114 --STG-HTTPLPVTDTSSASTGHATSLPVTDTSSVSTGHTTPLHVTDASSASTGQATPLP 1170
Query: 936 SSPLSGPPSPQLQPMPYQSPSSGTASSPSPA----TRMHSGQHSTQAQSTGQGGLSAPSS 991
+ LS + P+P SPSS + +P T S H+T T +S
Sbjct: 1171 VTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVTDASSVSTD-- 1228
Query: 992 LICHSLCDPASFPPDGATVSIKPEPEDREPNFATIGLQDITLDDDQFISDLEHQP 1046
H+ P + P +T P P + +T + + D +S + P
Sbjct: 1229 ---HATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTP 1280
Score = 50.8 bits (120), Expect = 7e-06
Identities = 74/321 (23%), Positives = 120/321 (37%), Gaps = 42/321 (13%)
Query: 751 IPQTYASMVTSSHLPQLQCRDESVSKEQHMIPSPIVHQPFQVTPTPPVGSSYQPMQTNVV 810
+P T S ++ H L D S + H P P+ T P +
Sbjct: 1185 LPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVTDASSVSTDHATSLPVTIPSAASTG 1244
Query: 811 YNGPTCLPI---NAASSQEFDSVLFQQDATLSGLVNLGCQPLSSIPFHSSNSGSTGHLLA 867
+ P LP+ ++AS+ + S+L +++S + +P S++S STGH+
Sbjct: 1245 HTTP--LPVTDTSSASTGQATSLLVTDTSSVS------TGDTTPLPVTSTSSASTGHV-- 1294
Query: 868 HTPHSVHTLPHLQSMGY---------HCSNTGQR------SLSSPVADQITGQPSSQLQP 912
TP V T P S G+ ++TG S SS T P +
Sbjct: 1295 -TPLHV-TSPSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASS 1352
Query: 913 ITYG---PSHSGSATTASPAASHPLASSPLSGPPSPQLQPMPYQSPSSGTASSPSPA--- 966
++ G P H A++AS + PL + LS + P+P SPSS + +P
Sbjct: 1353 VSTGHTTPLHVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVT 1412
Query: 967 -TRMHSGQHSTQAQSTGQGGLSAPSSLICHSLCDPASFPPDGATVSIKPEPEDREPNFAT 1025
T S H+T T +S H+ P + P +T P P + +T
Sbjct: 1413 DTSSASTGHATPLPVTDASSVSTD-----HATSLPVTIPSAASTGHTTPLPVTDTSSAST 1467
Query: 1026 IGLQDITLDDDQFISDLEHQP 1046
+ + D +S + P
Sbjct: 1468 GQATSLLVTDTSSVSTGDTTP 1488
Score = 48.5 bits (114), Expect = 3e-05
Identities = 62/270 (22%), Positives = 100/270 (37%), Gaps = 26/270 (9%)
Query: 750 SIPQTYASMVTSSHLPQLQCRDESVSKEQHMIPSPIVH----QPFQVTPTPPVGSSYQPM 805
S+P T S V++ H L D S + P P+ TP P P
Sbjct: 1136 SLPVTDTSSVSTGHTTPLHVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTS----PS 1191
Query: 806 QTNVVYNGPTCLPINAASSQEFDSVLFQQDATLSGLVNLGCQPLSSIPFHSSNSGSTGHL 865
+ + P + +++S + L DA+ ++ +S+P ++ STGH
Sbjct: 1192 SASTGHATPLLVTDTSSASTGHATPLPVTDAS-----SVSTDHATSLPVTIPSAASTGHT 1246
Query: 866 LAHTPHSVHTLPHLQSMGYHCSNTGQRSLSSPVADQITGQPSSQLQPITYGPSHSGSATT 925
+ Q+ ++T S +T S+ +T P H S ++
Sbjct: 1247 TPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVT--PLHVTSPSS 1304
Query: 926 ASPAASHPLASSPLSGPPSPQLQPMPYQSPSSGTASSPSP-----ATRMHSGQ----HST 976
AS + PL + LS + P+P SPSS + +P A+ + +G H T
Sbjct: 1305 ASTGHATPLPVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLHVT 1364
Query: 977 QAQ--STGQGGLSAPSSLICHSLCDPASFP 1004
A STGQ +SL S D P
Sbjct: 1365 DASSASTGQATPLPVTSLSSVSTGDTTPLP 1394
Score = 48.5 bits (114), Expect = 3e-05
Identities = 82/325 (25%), Positives = 121/325 (37%), Gaps = 59/325 (18%)
Query: 717 SLPVPHPAQ------TQRPSSDSGCSHDSVLSGQRSLICSIPQTYASMVTSSHLPQLQCR 770
SLPV P+ T P +D+ SV +G + S+P T AS V++ H L
Sbjct: 2704 SLPVTIPSSASSGHTTPLPVTDAS----SVSTGHAT---SLPVTDASSVSTGHATPLPVT 2756
Query: 771 DESVSKEQHMIPSPIVH----QPFQVTPTPPVGSSYQPMQTNVVYNGPTCLPINAASSQE 826
D S H P P+ TP P +S + T LP+ + SS
Sbjct: 2757 DASSVSTGHATPLPLTSLSSVSTGDTTPLPVTDTS------SASTGQATPLPVTSLSSVS 2810
Query: 827 FDSVLFQQDATLSGLVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHSVHTLPHLQSMGYHC 886
++ + +S+P ++S STGH TP LP +
Sbjct: 2811 TGDT---TPLPVTDTSSASTGHATSLPVTDTSSASTGHA---TP-----LPDTDTSS--- 2856
Query: 887 SNTGQRSL------SSPVADQITGQPSSQLQPITYG---PSHSGSATTASPAASHPLASS 937
++TG +L SS T P + I+ G P H S ++AS + PL +
Sbjct: 2857 ASTGHATLLPVTDTSSASIGHATSLPVTDTSSISTGHATPLHVTSPSSASTGHATPLPVT 2916
Query: 938 PLSGPPSPQLQPMPYQSPSSGTA--SSPSPATRMHSGQHSTQAQSTGQGGLSAPSSLICH 995
S + P+ SPSS + ++P P T T + STG +SL
Sbjct: 2917 DTSSASTGHANPLHVTSPSSASTGHATPLPVT-------DTSSASTGHATPLPVTSLSSV 2969
Query: 996 SLCD----PASFPPDGATVSIKPEP 1016
S D P + P +T P P
Sbjct: 2970 STGDTTPLPVTSPSSASTGHTTPLP 2994
Score = 47.8 bits (112), Expect = 6e-05
Identities = 67/276 (24%), Positives = 97/276 (35%), Gaps = 49/276 (17%)
Query: 718 LPVPHPAQ------TQRPSSDSGCSHDSVLSGQRSLICSIPQTYASMVTSSHLPQLQCRD 771
LPV P+ T P +D+ SV +G + S+P T S ++ H L D
Sbjct: 2129 LPVTSPSSASTGDTTPLPVTDTS----SVSTGHAT---SLPVTDTSSASTGHATSLPVTD 2181
Query: 772 ESVSKEQHMIPSPIVHQPFQVTPTPPVGSSYQPMQTNVVYNGPTCLPINAASSQEFDSVL 831
S + H P P+ T + G + T LP+ + SS +
Sbjct: 2182 TSSASTGHATPLPVTD-----TSSASTGQA-------------TPLPVTSPSSASTGHAI 2223
Query: 832 FQQDATLSGLVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHSVHTLPHLQSMGYHCSNTGQ 891
S PL S+++G T L SV T H ++
Sbjct: 2224 PLLVTDTSSASTGQATPLPVTSLSSASTGDTTPLPVTDASSVST--------GHATSLPV 2275
Query: 892 RSLSSPVADQITGQPSSQLQPITYG---PSHSGSATTASPAASHPLASSPLSGPPSPQLQ 948
SLSS T P + + G P H A++AS + PL + LS +
Sbjct: 2276 TSLSSVSTGDTTPLPVTSPSSASTGHATPLHVTDASSASTGHATPLPVTSLSSASTGDTT 2335
Query: 949 PMPYQSPSSGTASSPSPATRMHSGQHSTQAQSTGQG 984
P+P SPSS + +P H T A S G
Sbjct: 2336 PLPVTSPSSASTGHATPL-------HVTDASSVSTG 2364
Score = 46.2 bits (108), Expect = 2e-04
Identities = 48/219 (21%), Positives = 82/219 (37%), Gaps = 15/219 (6%)
Query: 751 IPQTYASMVTSSHLPQLQCRDESVSKEQHMIPSPIVH----QPFQVTPTPPVGSSYQPMQ 806
+P T AS V++ H L D S + P P+ TP P P
Sbjct: 1345 LPVTDASSVSTGHTTPLHVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTS----PSS 1400
Query: 807 TNVVYNGPTCLPINAASSQEFDSVLFQQDATLSGLVNLGCQPLSSIPFHSSNSGSTGHLL 866
+ + P + +++S + L DA+ ++ +S+P ++ STGH
Sbjct: 1401 ASTGHATPLLVTDTSSASTGHATPLPVTDAS-----SVSTDHATSLPVTIPSAASTGHTT 1455
Query: 867 AHTPHSVHTLPHLQSMGYHCSNTGQRSLSSPVADQITGQPSSQLQPITYGPSHSGSATTA 926
+ Q+ ++T S +T S+ +T P H S ++A
Sbjct: 1456 PLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVT--PLHVTSPSSA 1513
Query: 927 SPAASHPLASSPLSGPPSPQLQPMPYQSPSSGTASSPSP 965
S + PL + LS + P+P SPSS + +P
Sbjct: 1514 STGHATPLPVTSLSSASTGDTMPLPVTSPSSASTGDTTP 1552
Score = 41.6 bits (96), Expect = 0.004
Identities = 59/230 (25%), Positives = 79/230 (34%), Gaps = 31/230 (13%)
Query: 751 IPQTYASMVTSSHLPQLQCRDESVSKEQHMIPSPIVHQPF----QVTPTPPVGSSYQPMQ 806
+P T AS V++ H L S + H P P+ TP P P
Sbjct: 1553 LPVTDASSVSTGHTTPLPVTSPSSASTGHTTPLPVTDTSSASKGDTTPLPVTS----PSS 1608
Query: 807 TNVVYNGPTCLPINAASSQEFDSVLFQQDATLSGLVNLGCQPLSSIPFHSSNSGSTGHLL 866
+ + P LP+ SS S L PL S +S STGH
Sbjct: 1609 ASTGHTTP--LPVTDTSSASTGDTTPLPVTNASSLSTGHATPLHVT---SPSSASTGHA- 1662
Query: 867 AHTPHSVHTLPHLQSMGYHCSNTGQRSLSSPVADQITGQPSSQLQPITYGPSHSGSATTA 926
TP V T S G H + LSS D T P + + ++A
Sbjct: 1663 --TPLPV-TSTSSASTG-HATPLPVTGLSSATTDDTTRLPVTDV-------------SSA 1705
Query: 927 SPAASHPLASSPLSGPPSPQLQPMPYQSPSSGTASSPSPATRMHSGQHST 976
S + PL + LS + P+P SPSS + SP + ST
Sbjct: 1706 STGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHASPLLVTDASSAST 1755
Score = 41.6 bits (96), Expect = 0.004
Identities = 60/255 (23%), Positives = 86/255 (33%), Gaps = 28/255 (10%)
Query: 750 SIPQTYASMVTSSHLPQLQCRDESVSKEQHMIPSPIVHQPFQVTPTPPVGSSYQPMQTNV 809
S+P T S +++ H L S + H P P+ T P +
Sbjct: 2880 SLPVTDTSSISTGHATPLHVTSPSSASTGHATPLPVTDTSSASTGHANPLHVTSPSSAST 2939
Query: 810 VYNGPTCLPINAASSQEFDSVLFQQDATLSGLVNLGCQPLSSIPFHSSNSGSTGHLLAHT 869
+ P LP+ SS +LS + PL P S +S STGH T
Sbjct: 2940 GHATP--LPVTDTSSASTGHATPLPVTSLSSVSTGDTTPL---PVTSPSSASTGHT---T 2991
Query: 870 PHSVHTLPHLQSMGYHCSNTGQRSLSSPVADQITGQPSSQLQPITYGPSHSGSATTASPA 929
P V ++T S A +T S+ T P ++AS
Sbjct: 2992 PLPV-------------TDTSSASTGQATALPVTSTSSASTGDTT--PLPVTDTSSASTG 3036
Query: 930 ASHPLASSPLSGPPSPQLQPMPYQSPSSGTASSPSPATRMHSGQHSTQAQSTGQGGLSAP 989
+ PL + LS + P+P SPSS + +P + STGQ
Sbjct: 3037 QATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLL-----VTDASSASTGQATPLPV 3091
Query: 990 SSLICHSLCDPASFP 1004
+SL S D P
Sbjct: 3092 TSLSSVSTGDTTPLP 3106
Score = 41.2 bits (95), Expect = 0.005
Identities = 68/280 (24%), Positives = 111/280 (39%), Gaps = 34/280 (12%)
Query: 751 IPQTYASMVTSSHLPQLQCRDESVSKEQHMIPSPIVHQPFQVTPTPPVGSSYQPMQTNVV 810
+P T S ++ H L D S + H P P+ T P +
Sbjct: 1393 LPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVTDASSVSTDHATSLPVTIPSAASTG 1452
Query: 811 YNGPTCLPI---NAASSQEFDSVLFQQDATLSGLVNLGCQPLSSIPFHSSNSGSTGHLLA 867
+ P LP+ ++AS+ + S+L +++S + +P S++S STGH+
Sbjct: 1453 HTTP--LPVTDTSSASTGQATSLLVTDTSSVS------TGDTTPLPVTSTSSASTGHV-- 1502
Query: 868 HTPHSVHTLPHLQSMGYHCSNTGQRSLSSPVADQITGQPSSQLQPITYGPSHSGSATTAS 927
TP V T P S G H + SLSS TG + P+T S ++AS
Sbjct: 1503 -TPLHV-TSPSSASTG-HATPLPVTSLSSAS----TGD--TMPLPVT-------SPSSAS 1546
Query: 928 PAASHPLASSPLSGPPSPQLQPMPYQSPSSGTA--SSPSPATRMHSGQHSTQAQSTGQGG 985
+ PL + S + P+P SPSS + ++P P T S +++ +T
Sbjct: 1547 TGDTTPLPVTDASSVSTGHTTPLPVTSPSSASTGHTTPLPVTDTSS---ASKGDTTPLPV 1603
Query: 986 LSAPSSLICHSLCDPASFPPDGATVSIKPEPEDREPNFAT 1025
S S+ H+ P + +T P P + +T
Sbjct: 1604 TSPSSASTGHTTPLPVTDTSSASTGDTTPLPVTNASSLST 1643
Score = 39.7 bits (91), Expect = 0.015
Identities = 60/268 (22%), Positives = 96/268 (35%), Gaps = 31/268 (11%)
Query: 750 SIPQTYASMVTSSHLPQLQCRDESVSKEQHMIPSPIVHQ---------PFQVTPTPPVGS 800
S+P T AS V++ H L D S P P+ P VT V +
Sbjct: 1856 SLPVTDASSVSTGHATSLLVTDASSVSTGDTTPLPVTDTNSASTGDTTPLHVTDASSVST 1915
Query: 801 SYQPMQ-----TNVVYNGPTCLPINAASSQEFDSVLFQQDATLSGLVNLGCQPLSSIPFH 855
+ ++ T LP+ + SS ++ ++ +S+P
Sbjct: 1916 GHATSLPVTSLSSASTGDTTPLPVTSPSSASSGHTT---PLPVTDASSVPTGHATSLPVT 1972
Query: 856 SSNSGSTGHLLAHTPHSVHTLPHLQSMGYHCSNTGQRSLSSPVADQITGQPSSQLQPITY 915
++S STGH TP V + + H + SS Q T P + L +
Sbjct: 1973 DASSVSTGHA---TPLPVTDASSVSTG--HATPLPVTDTSSVSTGQATPLPVTSLSSAST 2027
Query: 916 G---PSHSGSATTASPAASHPLASSPLSGPPSPQLQPMPYQSPSSGTASSPSP-----AT 967
G P ++AS PL + LS + P+P SPSS + +P A+
Sbjct: 2028 GDTTPLPVTDTSSASTGQDTPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDAS 2087
Query: 968 RMHSGQHSTQAQSTGQGGLSAPSSLICH 995
+ +G H+T T +S + H
Sbjct: 2088 SVSTG-HATSLLVTDASSVSTGHATALH 2114
Score = 39.3 bits (90), Expect = 0.020
Identities = 77/311 (24%), Positives = 110/311 (35%), Gaps = 65/311 (20%)
Query: 718 LPVPHPAQ------TQRPSSDSGCSHDSVLSGQRSLICSIPQTYASMVTSSHLPQLQCRD 771
LPV P+ T P +D+ SV +G + S+P T AS V++ H L D
Sbjct: 1937 LPVTSPSSASSGHTTPLPVTDAS----SVPTGHAT---SLPVTDASSVSTGHATPLPVTD 1989
Query: 772 ESVSKEQHMIPSPIVHQPF----QVTPTPPVGSSYQPMQTNVVYNGPTCLPINAASSQEF 827
S H P P+ Q TP P S + T LP+ SS
Sbjct: 1990 ASSVSTGHATPLPVTDTSSVSTGQATPLPVTSLS------SASTGDTTPLPVTDTSSAST 2043
Query: 828 DSVLFQQDATL--SGLVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHSVHTLPHLQSMGYH 885
QD L + L ++ + +P S +S STGH TP V
Sbjct: 2044 G-----QDTPLPVTSLSSVSTGDTTPLPVTSPSSASTGHA---TPLLV------------ 2083
Query: 886 CSNTGQRSLSSPVADQITGQPSSQLQPITYGPSHSGSATTASPAASHPLASSPLSGPPSP 945
T S+S TG +S L + + S +T A H +S LS +
Sbjct: 2084 ---TDASSVS-------TGHATSLLV------TDASSVSTGHATALHVTDASSLS---TG 2124
Query: 946 QLQPMPYQSPSSGTASSPSPATRMHSGQHSTQAQSTGQGGLSAPSSLICHSLCDPASFPP 1005
P+P SPSS + +P + ST +T S+ H+ P +
Sbjct: 2125 DTTPLPVTSPSSASTGDTTPLPVTDTSSVST-GHATSLPVTDTSSASTGHATSLPVTDTS 2183
Query: 1006 DGATVSIKPEP 1016
+T P P
Sbjct: 2184 SASTGHATPLP 2194
Score = 39.3 bits (90), Expect = 0.020
Identities = 64/239 (26%), Positives = 90/239 (37%), Gaps = 31/239 (12%)
Query: 754 TYASMVTSSHLPQLQCRDESVSKEQHMIPSPIVHQPF----QVTPTP-PVGSSYQPMQTN 808
T AS V++ H L D S + P+ Q TP P + SS T
Sbjct: 3524 TDASSVSTGHATPLPVTDTSSASTGDTTRLPVTDTSSASTGQATPLPVTIPSSSSSGHT- 3582
Query: 809 VVYNGPTCLPINAASSQEFDSVLFQQDATLSGLVNLGCQPLSSIPFHSSNSGSTGH---L 865
T LP+ + SS V + S PL P S++S STGH L
Sbjct: 3583 ------TPLPVTSTSSVSTGHVTPLHVTSPSSASTGHVTPL---PVTSTSSASTGHATPL 3633
Query: 866 LAHTPHSVHT-----LPHLQSMGYHCSNTGQRSL---SSPVADQITGQPSSQLQPITYGP 917
L SV T LP + +T + SS Q T P + L ++ G
Sbjct: 3634 LVTDASSVSTGHATPLPVTDASSASTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGD 3693
Query: 918 SHSGSATTASPAASHPLASSPLSGPPSPQL---QPMPYQSPSSGTA--SSPSPATRMHS 971
+ T AS A++ P++ P S P+P SPSS + ++P P T + S
Sbjct: 3694 TTPLPVTDASSASTGHATPLPVTIPSSVSTGDTMPLPVTSPSSASTGHATPLPVTGLSS 3752
Score = 38.5 bits (88), Expect = 0.034
Identities = 61/245 (24%), Positives = 85/245 (34%), Gaps = 33/245 (13%)
Query: 750 SIPQTYASMVTSSHLPQLQCRDESVSKEQHMIPSPIVHQPFQVTPTPPVGSSYQPMQTNV 809
S+P T S ++ H L D S H P P VT T V + +
Sbjct: 3840 SLPVTSRSSASTGHATPLPVTDTSSVSTGHATPLP-------VTSTSSVSTGH------- 3885
Query: 810 VYNGPTCLPINAASSQEFDSVLFQQDATLSGLVNLGCQPLSSIPFHSSNSGSTGHLLAHT 869
T LP+ + SS S ++ + + +P +++S STGH T
Sbjct: 3886 ----ATPLPVTSPSSA---STGHATPVPVTSTSSASTGDTTPLPVTNASSLSTGHA---T 3935
Query: 870 PHSVHTLPHLQSMGYHCSNTGQRSLSSPVADQITGQPSSQLQPITYG---PSHSGSATTA 926
P V T P S G S SS T P + L ++ G P ++A
Sbjct: 3936 PLHV-TSPSSASRG-DTSTLPVTDASSASTGHATPLPLTSLSSVSTGDTTPLPVTDTSSA 3993
Query: 927 SPAASHPLASSPLSGPPSPQLQPMPYQSPSSG----TASSPSPATRMHSGQHSTQAQSTG 982
S + PL + LS + P+P PSS T S P S H T T
Sbjct: 3994 STGQATPLPVTSLSSVSTGDTTPLPVTIPSSASSGHTTSLPVTDASSVSTGHGTPLPVTS 4053
Query: 983 QGGLS 987
S
Sbjct: 4054 TSSAS 4058
Score = 37.4 bits (85), Expect = 0.076
Identities = 59/256 (23%), Positives = 89/256 (34%), Gaps = 25/256 (9%)
Query: 751 IPQTYASMVTSSHLPQLQCRDESVSKEQHMIPSPIVH----QPFQVTPTPPVGSSYQPMQ 806
+P T S ++ H L D S + P P+ TP P G S
Sbjct: 1729 LPVTSPSSASTGHASPLLVTDASSASTGQATPLPVTDTSSVSTAHATPLPVTGLS----- 1783
Query: 807 TNVVYNGPTCLPINAASSQEFDSVLFQQDATLSGLVNLGCQPLSSIPFHSSNSGSTGHLL 866
+ + T LP+ SS + + S PL S+++G T L
Sbjct: 1784 -SASTDDTTRLPVTDVSSASTGQAIPLPVTSPSSASTGDTTPLPVTDASSASTGDTTSLP 1842
Query: 867 AHTPHSV---HT--LPHLQSMGY---HCSNTGQRSLSSPVADQITGQPSSQLQPITYG-- 916
P S HT LP + H ++ SS T P + + G
Sbjct: 1843 VTIPSSASSGHTTSLPVTDASSVSTGHATSLLVTDASSVSTGDTTPLPVTDTNSASTGDT 1902
Query: 917 -PSHSGSATTASPAASHPLASSPLSGPPSPQLQPMPYQSPSSGTA--SSPSPATRMHS-- 971
P H A++ S + L + LS + P+P SPSS ++ ++P P T S
Sbjct: 1903 TPLHVTDASSVSTGHATSLPVTSLSSASTGDTTPLPVTSPSSASSGHTTPLPVTDASSVP 1962
Query: 972 GQHSTQAQSTGQGGLS 987
H+T T +S
Sbjct: 1963 TGHATSLPVTDASSVS 1978
Score = 35.8 bits (81), Expect = 0.22
Identities = 49/216 (22%), Positives = 74/216 (34%), Gaps = 31/216 (14%)
Query: 754 TYASMVTSSHLPQLQCRDESVSKEQHMIP----SPIVHQPFQVTPTPPVGSSYQPMQTNV 809
T S V++ H L D S + H P SP TP P +S +V
Sbjct: 3172 TETSSVSTGHATPLLVTDASSASTGHATPLHVTSPSSASTGDTTPVPVTDTS------SV 3225
Query: 810 VYNGPTCLPINAASSQEFDSVLFQQDATLSGLVNLGCQPLSSIPFHSSNSGSTGHLLAHT 869
T LP+ SS +S PL S ++G T L +
Sbjct: 3226 STGHATPLPVTGLSSASTGDTTRLPVTDISSASTGQATPLPVTNTSSVSTGDTMPLPVTS 3285
Query: 870 PHSVHTLPHLQSMGYHCSNTGQRSLSSPVADQITGQPSSQLQPITYGPSHSGSATTASPA 929
P S T H + +++ ++PV P+T S ++AS
Sbjct: 3286 PSSAST-GHATPLPVTSTSSASTGHATPV-------------PVT-------STSSASTG 3324
Query: 930 ASHPLASSPLSGPPSPQLQPMPYQSPSSGTASSPSP 965
+ PL + S + P+P SPSS + +P
Sbjct: 3325 HTTPLPVTDTSSASTGDTTPLPVTSPSSASTGHTTP 3360
Score = 34.7 bits (78), Expect = 0.49
Identities = 55/238 (23%), Positives = 85/238 (35%), Gaps = 24/238 (10%)
Query: 751 IPQTYASMVTSSHLPQLQCR-DESVSKEQHM---IPSPIVHQPFQVTPTPPVGSSYQPMQ 806
+P T AS ++ H L SVS M + SP TP P G S
Sbjct: 3697 LPVTDASSASTGHATPLPVTIPSSVSTGDTMPLPVTSPSSASTGHATPLPVTGLS----- 3751
Query: 807 TNVVYNGPTCLPINAASSQEFDSVLFQQDATLSGLVNLGCQPLSSIPFHSSNSGSTGHLL 866
+ T LP+ SS S ++ + + +P +S STGH
Sbjct: 3752 -SASTGDTTPLPVTDTSSA---STRHATPLPVTDTSSASTDDTTRLPVTDVSSASTGHAT 3807
Query: 867 AHTPHSVHTLPHLQSMGYHCSNTGQRSLSSPVADQITGQPSSQLQPITYGPSHSGSATTA 926
S + + ++T S + +T + S+ T P S+ +
Sbjct: 3808 PLPVTSTSSASTGDTTPLPVTDTSSVSTGHATSLPVTSRSSASTGHATPLPVTDTSSVST 3867
Query: 927 SPAASHPLASSPLSGPPSPQLQPMPYQSPSSGTA--SSPSPATRMHSGQHSTQAQSTG 982
A P+ S+ S + P+P SPSS + ++P P T ST + STG
Sbjct: 3868 GHATPLPVTST--SSVSTGHATPLPVTSPSSASTGHATPVPVT-------STSSASTG 3916
Score = 33.9 bits (76), Expect = 0.84
Identities = 48/193 (24%), Positives = 70/193 (36%), Gaps = 37/193 (19%)
Query: 157 YRESSLSPSPASSI----SSRSWFSDASSCESLSHIYDDVDSELNEAAARFTLGSPLTSP 212
+ SS SP + I + +W S SS + ++ S AA R G+P T
Sbjct: 466 HERSSFSPGVSQEIFTLHETTTWPSSFSSKGHTTWSQTELPSTSTGAATRLVTGNPSTGT 525
Query: 213 GG---------SPGGCPGEETWHQQY--------GLGHSLSPRQSP-------CHSPRSS 248
G S G PGE T + + G G Q SP S
Sbjct: 526 AGTIPRVPSKVSAIGEPGEPTTYSSHSTTLPKTTGAGAQTQWTQETGTTGEALLSSPSYS 585
Query: 249 VTDENWLSPRPASGP-----SSRPTSPCGKRRHSSAEVCYAGSLSPHHSP-VPSPGHSPR 302
VT + P+S P +S+ + HS+ ++ S SP SP V GH+
Sbjct: 586 VTQMIKTATSPSSSPMLDRHTSQQITTAPSTNHST---IHSTSTSPQESPAVSQRGHTQA 642
Query: 303 GSVTEDTWLNASV 315
T+++ SV
Sbjct: 643 PQTTQESQTTRSV 655
Score = 33.5 bits (75), Expect = 1.1
Identities = 57/233 (24%), Positives = 83/233 (35%), Gaps = 25/233 (10%)
Query: 742 SGQRSLICSIPQTYASMVTSSHLPQLQCRDESVSKEQHMIPSPIVHQPF----QVTPTPP 797
S R ++P T AS ++ H L S P P+ Q TP P
Sbjct: 3944 SASRGDTSTLPVTDASSASTGHATPLPLTSLSSVSTGDTTPLPVTDTSSASTGQATPLPV 4003
Query: 798 VGSSYQPMQTNVVYNGPTCLPINAASSQEFDSVLFQQDATLSGLVNLGCQPLSSIPFHSS 857
+S + T P +P +A+S + + +G + +P S+
Sbjct: 4004 --TSLSSVSTGDTTPLPVTIPSSASSGHTTSLPVTDASSVSTGHG-------TPLPVTST 4054
Query: 858 NSGSTGHLLAHTPHSVHTLPHLQSMGYHCSNTGQRSLSSPVADQITGQPSSQLQPITYG- 916
+S STG TP V T S G H + SS T P + L ++ G
Sbjct: 4055 SSASTGDT---TPLPV-TDTSSASTG-HATPLPVTDTSSASTGHATPLPVTSLSSVSTGH 4109
Query: 917 --PSHSGSATTASPAASHPLASSPLSGPPSPQLQPMPYQSPSSGTASSPSPAT 967
P SAT+AS +S G +P L+ TA+SP P T
Sbjct: 4110 ATPLAVSSATSASTVSSDSPLKMETPGMTTPSLKT----DGGRRTATSPPPTT 4158
Score = 33.1 bits (74), Expect = 1.4
Identities = 78/310 (25%), Positives = 117/310 (37%), Gaps = 41/310 (13%)
Query: 713 SSVPSLPVPHPAQ--TQRPSSDSGCSHDSVLSGQRSLICS------IPQT-YASMVTSSH 763
SS P L H +Q T PS++ H + S Q S S PQT S T S
Sbjct: 597 SSSPMLD-RHTSQQITTAPSTNHSTIHSTSTSPQESPAVSQRGHTQAPQTTQESQTTRSV 655
Query: 764 LPQLQCRD-----ESVSKEQHMIPSPIVHQPFQVTPTPPVGSSYQPMQTNVVYNGPTCLP 818
P + S + H PS IV Q PT +++ P T +
Sbjct: 656 SPMTDTKTVTTPGSSFTASGHS-PSEIVPQD---APTISAATTFAPAPTGDGHTTQAPTT 711
Query: 819 INAASSQEFDSVLFQQDATL---SGLVNLGCQPLSS--------IPFHSSNSGSTGHLLA 867
A+ D+ L T +G + L +S+ +S S T +
Sbjct: 712 ALQAAPSSHDATLGPSGGTSLSKTGALTLANSVVSTPGGPEGQWTSASASTSPDTAAAMT 771
Query: 868 HTPHSVHTLPHLQSMGYHCSNTGQRSLSSPVADQITGQPSSQLQPITYGPSHSGSAT--T 925
HT + T Q+ +++G R+ S+ A + S + G S SG T +
Sbjct: 772 HTHQAESTEASGQTQTSEPASSGSRTTSAGTATPSSSGASGTTPSGSEGISTSGETTRFS 831
Query: 926 ASPAA-SHPLASSP--LSGPPSPQLQPMPYQSPSSGTASSPSPAT-RMHSGQHSTQAQST 981
++P+ SH S+ LS S P+ S+G ASS P T + ST + T
Sbjct: 832 SNPSRDSHTTQSTTELLSASASHGAIPV-----STGMASSIVPGTFHPTLSEASTAGRPT 886
Query: 982 GQGGLSAPSS 991
GQ ++PS+
Sbjct: 887 GQSSPTSPSA 896
Score = 32.3 bits (72), Expect = 2.4
Identities = 70/288 (24%), Positives = 100/288 (34%), Gaps = 31/288 (10%)
Query: 751 IPQTYASMVTSSHLPQLQCRDESVSKEQHMIPSPIVHQPFQVTPTPPVGSSYQPMQTNVV 810
+P T S V++ L S + H P+ T +S T+
Sbjct: 3089 LPVTSLSSVSTGDTTPLPVTSPSSASTGHATSLPVTDTSSASTGDT---TSLPVTDTSSA 3145
Query: 811 YNGPTC-LPINAASSQEFDSVLFQQDATLSGLVNLGCQPLSSIPFHSSNSGSTGHLLAHT 869
Y G T LP+ SS S + PL ++S STGH T
Sbjct: 3146 YTGDTTSLPVTDTSSSSTGDTTPLLVTETSSVSTGHATPLLVT---DASSASTGHA---T 3199
Query: 870 PHSVHTLPHLQSMG----YHCSNTGQRSLSSPVADQITGQPSSQLQPITYGPSHSGSATT 925
P V T P S G ++T S +TG S+ T P S+
Sbjct: 3200 PLHV-TSPSSASTGDTTPVPVTDTSSVSTGHATPLPVTGLSSASTGDTTRLPVTDISS-- 3256
Query: 926 ASPAASHPLASSPLSGPPSPQLQPMPYQSPSSGTA--SSPSPATRMHSGQHSTQAQSTGQ 983
AS + PL + S + P+P SPSS + ++P P T ST + STG
Sbjct: 3257 ASTGQATPLPVTNTSSVSTGDTMPLPVTSPSSASTGHATPLPVT-------STSSASTGH 3309
Query: 984 GG----LSAPSSLICHSLCDPASFPPDGATVSIKPEPEDREPNFATIG 1027
S S+ H+ P + +T P P P+ A+ G
Sbjct: 3310 ATPVPVTSTSSASTGHTTPLPVTDTSSASTGDTTPLPV-TSPSSASTG 3356
Score = 32.0 bits (71), Expect = 3.2
Identities = 64/269 (23%), Positives = 101/269 (37%), Gaps = 40/269 (14%)
Query: 724 AQTQRPSSDSGCSHDSVLSGQRSLICSIPQTYASMVTSSHLPQLQCRDESVSKEQHMIPS 783
AQTQ + ++G + +++LS S S+ Q + + S P L D S++ PS
Sbjct: 563 AQTQW-TQETGTTGEALLS---SPSYSVTQMIKTATSPSSSPML---DRHTSQQITTAPS 615
Query: 784 PIVHQPFQVTPTPPVGSSYQPMQTNVVYNGPTCLPINAASSQEFDSVLFQQDATLSGLVN 843
H T T P S V G T P SQ SV D
Sbjct: 616 TN-HSTIHSTSTSPQESPA------VSQRGHTQAPQTTQESQTTRSVSPMTDT------- 661
Query: 844 LGCQPLSSIPFHSSNSGSTGHLLAH-TPHSVHTLPHLQSMGYHCSNTGQRSLSSPVADQI 902
++ S+ ++GH + P T+ + + + TG + +
Sbjct: 662 ------KTVTTPGSSFTASGHSPSEIVPQDAPTISAATT--FAPAPTGDGHTTQAPTTAL 713
Query: 903 TGQPSSQLQPITYGPSHSGSATTASPAASHPLASSPLSGPPSPQLQPMPYQSPSSGTASS 962
PSS T GPS T+ S + LA+S +S P P+ Q S+ ++S
Sbjct: 714 QAAPSSH--DATLGPS---GGTSLSKTGALTLANSVVSTPGGPE-----GQWTSASASTS 763
Query: 963 PSPATRMHSGQHSTQAQSTGQGGLSAPSS 991
P A M + +++GQ S P+S
Sbjct: 764 PDTAAAMTHTHQAESTEASGQTQTSEPAS 792
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 54.3 bits (129), Expect = 6e-07
Identities = 80/302 (26%), Positives = 114/302 (37%), Gaps = 23/302 (7%)
Query: 712 LSSVPSLPVPHPAQTQRPSSDSGCSHDSVLSGQRSLICSIPQTYASMVTSSHLPQLQCRD 771
L ++P + VPH + + S L SL Q S +T S Q Q
Sbjct: 383 LQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPR-QTQASL 441
Query: 772 ESVSKEQHMIP-SPIVHQPFQVTPTPPVGSSYQPMQTNVVYNGPTCLPINAASSQEFDSV 830
S S+ P SP + P + +PP+ +S P + + + T P+ A SS S
Sbjct: 442 TSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPA-VSPLSSPLTIHPLQALSSLASHS- 499
Query: 831 LFQQDATLSGLVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHSVHTLP--HLQSMGYHCSN 888
A LS L+ + SS+ S L P S+ T P +L S+
Sbjct: 500 ---PQAPLSSLIMPPLETQSSLAPPS---------LQTPPASLTTPPLENLPSLAPPPLQ 547
Query: 889 TGQRSLSSPVADQITGQPSSQLQ----PITYGPSHSGSATTASPAASHP-LASSPLSGPP 943
T L++P + LQ P+T P + S+ P + P LAS PL G P
Sbjct: 548 TASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLP 607
Query: 944 SPQLQPMPYQSPSSGTASSPSPATRMHSGQHSTQAQSTGQGGLSAPSSLICHSLCDPASF 1003
SP L P+ P + + P S S AP++L H L P S
Sbjct: 608 SPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSP 667
Query: 1004 PP 1005
PP
Sbjct: 668 PP 669
Score = 38.5 bits (88), Expect = 0.034
Identities = 39/151 (25%), Positives = 55/151 (36%), Gaps = 28/151 (18%)
Query: 887 SNTGQRSLSSPVADQITGQPSSQ----LQPITYGPSHSGSATTASPAASHPLASSPLSG- 941
+ +G + +P A QP + L+P P +A P +S PLA+ SG
Sbjct: 253 ARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGT 312
Query: 942 ------PPSPQLQPMPYQSPSSGTASSPSPATRMHSGQHSTQAQSTGQGGLSAPSSLICH 995
PP P+P P S ++P P SAP SL
Sbjct: 313 KARPVPPPDNAATPLPATLPPSPPLATPLP---------------LAPPSPSAPPSL--Q 355
Query: 996 SLCDPASFPPDGATVSIKPEPEDREPNFATI 1026
+L P + PP A S+ P P+ TI
Sbjct: 356 TLPSPPATPPSQAPPSMTTPPMQAPPSLQTI 386
Score = 36.6 bits (83), Expect = 0.13
Identities = 44/174 (25%), Positives = 55/174 (31%), Gaps = 30/174 (17%)
Query: 895 SSPVADQIT----GQPSSQLQPITYGPSHSGSATTASPAASHPLASSPLSGPPSPQLQPM 950
S PV+ T PS P+ PS S + A P A PL+ PP Q+ P
Sbjct: 682 SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL-QVPPS 740
Query: 951 PYQSPSSGTASSPSPATRMHSGQHSTQAQSTGQGGLSAPSSLICHSLCDPASFPPDGATV 1010
P SP +++P P P L L P S P
Sbjct: 741 PPASPPMSPSATPPP---------------------RVPPLLAAPPLQVPPSPPASLPMS 779
Query: 1011 SIKPEPEDREPNFATIGLQDITLDDDQFISDLEHQPSGSAEKWPNHSVLSCPAP 1064
+ P P AT LQ + F PS S P L+ P P
Sbjct: 780 PLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSP----LATPPP 829
Score = 32.0 bits (71), Expect = 3.2
Identities = 69/314 (21%), Positives = 106/314 (33%), Gaps = 26/314 (8%)
Query: 717 SLPVPHPAQTQRPSSDSGCSHDSVLSGQRSLICSIPQTYASMVTSSHLPQLQCRDESVSK 776
SLP P QT + S S + ++L + + ++S +P L+ +
Sbjct: 462 SLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPP 521
Query: 777 EQHMIPSPIVHQPFQVTPT---PPVGSSYQPMQTNVVYNGPTCLPINA-ASSQEFDSVLF 832
P+ + P + P+ PP+ ++ P+ T + P P A +
Sbjct: 522 SLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPP 581
Query: 833 QQDATLSGLVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHSVH--TLPHLQSMGYHCSNTG 890
+ ++++ L+S P S L P + LP LQ+ ++
Sbjct: 582 ETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPP 641
Query: 891 QRSLSSPVADQITGQPSSQLQPITYGPSHSGSATTASPAASHPLASSPLSGPPS---PQL 947
L++P LQ P SP AS P+ SP + PPS P L
Sbjct: 642 LSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV--SPSATPPSQAPPSL 699
Query: 948 QPMPYQSPSSGTASSPSPATRMHSGQHSTQAQSTGQGGLSAPSSLICHSLCDPASFPPDG 1007
P Q P S AS P + Q AP L L P S PP
Sbjct: 700 AAPPLQVPPSPPASPPMSPSATPPPQ--------------APPPLAAPPLQVPPS-PPAS 744
Query: 1008 ATVSIKPEPEDREP 1021
+S P R P
Sbjct: 745 PPMSPSATPPPRVP 758
Score = 30.8 bits (68), Expect = 7.1
Identities = 17/52 (32%), Positives = 26/52 (50%), Gaps = 3/52 (5%)
Query: 916 GPSHSGSATTASPAASHPLASSPLSGPPSPQLQPMPYQSP--SSGTASSPSP 965
GP+ S ++ +PA+ P + PP+ P P SP +SGT + P P
Sbjct: 78 GPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGT-TRPGP 128
Score = 30.4 bits (67), Expect = 9.3
Identities = 73/315 (23%), Positives = 107/315 (33%), Gaps = 47/315 (14%)
Query: 26 PPPPGSRPADLEPDDCASIYIFNVDPPPSTLTTPLCL----------------PHHGLPS 69
P P G++ + P D A+ + PP L TPL L P PS
Sbjct: 307 PSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPS 366
Query: 70 HS--SVLSPSFQLQSHKNYEGTCEIPESKYSP--LGGPKPFECPSIQITSI--SPNCHQ- 122
+ S+ +P Q ++P S SP P P S+Q T+ SP
Sbjct: 367 QAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQAT 426
Query: 123 ----ELDAHEDDLQINDPEREFLERPSRDHLYLPLE---PSYRESSLSPS---------- 165
+ + + P R P L PL ++SLSP+
Sbjct: 427 HSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTI 486
Query: 166 -PASSISSRSWFSDASSCESLSHIYDDVDSELNEAAARFTLGSPLTSP-GGSPGGCPGE- 222
P ++SS + S + SL + S L + + S T P P P
Sbjct: 487 HPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPL 546
Query: 223 ETWHQQYGLGHSLSPRQSPCHSPRSSVTDENWLSPRPASGPSSRPTSPCGKRRHSSAEVC 282
+T H +P PC +P + L+ P PSS T P + + A
Sbjct: 547 QTASAPLTTPHLETP---PCPAPCPLQAPPSPLTTPPPETPSSIATPP-PQAPPALASPP 602
Query: 283 YAGSLSPHHSPVPSP 297
G SP SP+ +P
Sbjct: 603 LQGLPSPPLSPLATP 617
Score = 30.4 bits (67), Expect = 9.3
Identities = 42/185 (22%), Positives = 61/185 (32%), Gaps = 13/185 (7%)
Query: 781 IPSPIVHQPFQVTPTPPVGSSYQPMQTNVVYNGPTCLPINAASSQEFDSVLFQQDATLSG 840
+P + P QV P+PP P+ P L + F A S
Sbjct: 757 VPPLLAAPPLQVPPSPPASLPMSPL-AKPPPQAPPALATPPLQALPSPPASFPGQAPFSP 815
Query: 841 LVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHSVHTLPHLQSMGYHCSNTGQRSLSSPVAD 900
+L PL++ P + + L P S P LQ+ R +P D
Sbjct: 816 SASLPMSPLATPPPQAPPVLAAP--LLQVPPSPPASPTLQA---------PRRPPTPGPD 864
Query: 901 QITGQPSSQLQPITYGPSHSGSATTASPAASHPLASSPLSGPPSPQLQPMPYQSPSSGTA 960
P L + GP S + +S + LA S +P+ P G A
Sbjct: 865 TSVSGPRLTL-ALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAA 923
Query: 961 SSPSP 965
+SP P
Sbjct: 924 ASPPP 928
>gi|91982772 mucin 17 [Homo sapiens]
Length = 4493
Score = 54.3 bits (129), Expect = 6e-07
Identities = 82/340 (24%), Positives = 126/340 (37%), Gaps = 25/340 (7%)
Query: 696 TYTPVLMKQEHREEIDLSSVPSLPVPHPAQTQRPSSDSGCSHDSVLSGQRSLICSIPQTY 755
T TPV + ++ S+P ++ P ++ S V+S + S + + P
Sbjct: 3308 TSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDT 3367
Query: 756 ASMVTSSHLPQLQCRDESVSKEQHMIPS----PIVHQPFQVTPTPPVGSSYQPMQTNVVY 811
++ VT+S L + PS P+ P V+ TP V S + T V
Sbjct: 3368 STPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMP--VSTTPVVSSEVNTLSTTPVD 3425
Query: 812 NGPTCLPINAASSQE--FDSVLFQQDATLSGLVNLGCQPLSSIPFHSSNSGSTGHLLAHT 869
+ ASS + T G L PLS+ P SS + + L+ T
Sbjct: 3426 SNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEAST----LSTT 3481
Query: 870 PHSVHTLPHLQSMGYHCSNTGQRSLSSPVADQITGQPSSQLQPITYGPSHSGSATTAS-- 927
P T P S + S T S P + G P++ P S A+T S
Sbjct: 3482 PVDTST-PVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTT 3540
Query: 928 PAASHPLASSPLSGPPSP---QLQPMPYQSPSSGTASSPS---PATRMHSGQHSTQAQST 981
P S+ +S SP Q+ M +PS G++S + +T + S + ST ST
Sbjct: 3541 PVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEAST--PST 3598
Query: 982 GQGGLSAPSSLICHSLCDPASFPPDGATVSIKPEPEDREP 1021
S P + S P PP+ T+ + E P
Sbjct: 3599 PSVDRSTPVTTSTQSNSTPT--PPEVITLPMSTPSEVSTP 3636
Score = 47.0 bits (110), Expect = 1e-04
Identities = 57/292 (19%), Positives = 113/292 (38%), Gaps = 32/292 (10%)
Query: 698 TPVLMKQEHREEIDLSSVPSLPVPHPAQTQRPSSDSGCSHDSVLSGQRSLICSIPQTYAS 757
TP+ E + S+P P++ P + S +V S + S + + P ++
Sbjct: 3251 TPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTST 3310
Query: 758 MVTS----SHLPQLQCRDESVSKEQHMIPSPIVHQPFQVTPTPPVGSSYQPMQTNVVYNG 813
VT+ S P + + +P+ + F TP V S + T V
Sbjct: 3311 PVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPV--VSSEASTLSTTPV--- 3365
Query: 814 PTCLPINAASSQEFDSVLFQQDATLSGLVNLGCQPLSSIPFHSSNSGSTG-HLLAHTPHS 872
T P+ ++ + + + + G PL+S+P ++ S+ + L+ TP
Sbjct: 3366 DTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVD 3425
Query: 873 VHTLPHLQSMGYHCSNTGQRSLSSPVADQITGQPSSQLQPITYGPSHSGSATTASPAASH 932
+TL T + SSP + T P+S ++ ++P +
Sbjct: 3426 SNTLV----------TTSTEASSSPTIAEGTSLPTST------------TSEGSTPLSIM 3463
Query: 933 PLASSPLSGPPSPQLQPMPYQSPSSGTASSPSPATRMHSGQHSTQAQSTGQG 984
PL+++P++ + L P + + T SSP+ ++ + S + G+G
Sbjct: 3464 PLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEG 3515
Score = 46.2 bits (108), Expect = 2e-04
Identities = 75/370 (20%), Positives = 133/370 (35%), Gaps = 43/370 (11%)
Query: 656 QGAHIVLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTPVLMKQEHREEIDLSSV 715
+G+ + VP P V++ H S + T TPV E +
Sbjct: 2394 EGSTPLTSVPVSTMPVVSSEASTH----------STTPVDTSTPVTTSTEASSSPTTAEG 2443
Query: 716 PSLPVPHPAQTQRPSSDSGCSHDSVLSGQRSLICSIPQTYASMVTSSHLPQLQCRDESVS 775
S+P P++ P + S V+S + + + P ++ +T+S + +
Sbjct: 2444 TSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTS----TEASSSPTT 2499
Query: 776 KEQHMIPSPIVHQ------PFQVTPTPPVGSSYQPMQTNVV-YNGPTCLPINAASSQEFD 828
E ++P + V+ TP + T V N P +SS
Sbjct: 2500 AEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSA 2559
Query: 829 SVLFQQDATLS-GLVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHSVHTLPHLQSMGYHCS 887
+T S G L P+S+ P SS + + L+ TP ++P
Sbjct: 2560 EGTSMPTSTYSEGSTPLRSMPVSTKPLASSEAST----LSTTPVDT-SIP---------V 2605
Query: 888 NTGQRSLSSPVADQITGQPSSQLQPITYGPSHSGSATTASPAASHPLASSPLSGPPSPQL 947
T + SSP + T P S PS ++ T+ ++ P+ASS S + +
Sbjct: 2606 TTSTETSSSPTTAKDTSMPIST-------PSEVSTSLTSILVSTMPVASSEASTLSTTPV 2658
Query: 948 QPMPYQSPSSGTASSPSPATRMHSGQHSTQAQSTGQGGLSAPSSLICHSLCDPASFPPDG 1007
+ S+GT+SSP+ A + +ST + ++L+ +S S P
Sbjct: 2659 DTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVD 2718
Query: 1008 ATVSIKPEPE 1017
+ + E
Sbjct: 2719 TSTPVTTSAE 2728
Score = 45.8 bits (107), Expect = 2e-04
Identities = 62/308 (20%), Positives = 116/308 (37%), Gaps = 32/308 (10%)
Query: 690 SQSQRFTYTPVLMKQEHREEIDLSSVP------SLPVPHPAQTQRPSSDSGCSHDSVLSG 743
S++ + TPV K + + SS P S+P P + P + H V S
Sbjct: 1175 SEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASS 1234
Query: 744 QRSLICSIPQTYASMVTSSHLPQLQCRDESVSKEQHMIPSPIVHQPFQVTPTPPVGSSYQ 803
+ S + + P ++ VT+S + + E +P+ + + + PV ++
Sbjct: 1235 EASTLSTSPVDTSTPVTTS----AETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLV 1290
Query: 804 PM-QTNVVYNGPTCLPINAASSQEFDSVLFQQDATL--SGLVNLGCQPLSSIPFHSSNSG 860
+ + + P +S E S + T + + G PL+SIP +++
Sbjct: 1291 TSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVA 1350
Query: 861 STGHLLAHTPHSVHTLPHLQSMGYHCSNTGQRSLSSPVADQITGQPSSQLQPITYGPSHS 920
S+ + T ++ P T + SSP + T P+S PS
Sbjct: 1351 SSAISILSTTPVDNSTP---------VTTSTEACSSPTTSEGTSMPNS-------NPSEG 1394
Query: 921 GSATTASPAASHPLASSPLSGPPSPQLQPMPYQSPSSGTASSPSPATRMHSGQHSTQAQS 980
+ T+ P ++ P+ SS S + P+ +P + +A + S T T S
Sbjct: 1395 TTPLTSIPVSTTPVVSSEAS---TLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPS 1451
Query: 981 TGQGGLSA 988
G+ L +
Sbjct: 1452 EGKTPLKS 1459
Score = 44.7 bits (104), Expect = 5e-04
Identities = 82/355 (23%), Positives = 135/355 (38%), Gaps = 44/355 (12%)
Query: 690 SQSQRFTYTPVLMKQEHREEIDLSSVPSLPVPHPAQTQRPSSDSGCSHDSVLSGQRSLIC 749
S++ T TPV E + +P+ P++ P + S V + S +
Sbjct: 3008 SRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLS 3067
Query: 750 SIP-QTYASMVTSSHLPQLQCRDESVSKEQHMI---PSPIVHQPFQVTPTPPVGSSYQPM 805
+ P + + +VTS+ + E S +P+ P V+ TP S+ +
Sbjct: 3068 TTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVP--VSTTPVTSSAISTL 3125
Query: 806 QTNVVYNGPTCLPINAASSQEFDSVLFQQDATLSGLVNLGCQPLSSIPFHS----SNSGS 861
T V T P+ ++ + + + + G PL+ +P + S+ S
Sbjct: 3126 STTPV---DTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDS 3182
Query: 862 TGHLLAHTPHSVHTLPHLQSMGYHCSNTGQRSLSSPVADQITGQPSSQLQPITYGP---- 917
T L+ TP V T + + S+T S P T PS + P+T P
Sbjct: 3183 T---LSATP--VDTSTPVTTSTEATSSTTAEGTSIP-----TSTPSEGMTPLTSVPVSNT 3232
Query: 918 ---SHSGSATTASPAASH-PLASS--PLSGPPSPQLQPMPYQSPSSGT---ASSPSPATR 968
S S + +P S+ PL +S S PP+ + MP +PS G+ S P T
Sbjct: 3233 PVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTT 3292
Query: 969 MHSGQHSTQAQSTGQGGLSAPSSLICHSLCDPASFPP--DGATVSIKPEPEDREP 1021
+ S + ST ST S P + + +S PP DG ++ E P
Sbjct: 3293 VASSETST--LSTTPADTSTPVT----TYSQASSSPPIADGTSMPTSTYSEGSTP 3341
Score = 44.3 bits (103), Expect = 6e-04
Identities = 79/345 (22%), Positives = 120/345 (34%), Gaps = 49/345 (14%)
Query: 696 TYTPVLMKQEHREEIDLSSVPSLPVPHPAQTQRPSSDSGCSHDSVLSGQRSLICSIPQTY 755
T TPV E + S+P+ P + + P + S V S + S + P
Sbjct: 2955 TRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADT 3014
Query: 756 ASMVTSSHLPQLQCRDESVSKEQHMIP--------SPIVHQPFQVTPTP-PVGSSYQPMQ 806
++ VT+S + + E IP +P+ P TP P S+
Sbjct: 3015 STPVTTS----TEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLS--T 3068
Query: 807 TNVVYNGPTCLPINAASSQEFDSVLFQQDATLSGLVNLGCQPLSSIPFHSSN-SGSTGHL 865
T V N P +SS +T S G PL+ +P ++ + S
Sbjct: 3069 TPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSE----GSTPLTGVPVSTTPVTSSAIST 3124
Query: 866 LAHTPHSVHTLPHLQSMGYHCSNTGQRSLSSPVADQITGQPSSQLQPITYGP-------S 918
L+ TP T P S H S T S P T PS P+TY P S
Sbjct: 3125 LSTTPVDTST-PVTTSTEAHSSPTTSEGTSMP-----TSTPSEGSTPLTYMPVSTMLVVS 3178
Query: 919 HSGSATTASP--------AASHPLASSPLSGPPSPQLQPMPYQSPSSGTASSPSPATRMH 970
S +A+P ++ +S+ G P P +P + S +P
Sbjct: 3179 SEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSE 3238
Query: 971 SGQHST------QAQSTGQGGLSAPSSLICHSLCDPASFPPDGAT 1009
+ ST +T S+P + S+ P S P +G+T
Sbjct: 3239 ASILSTTPVDSNTPLTTSTEASSSPPTAEGTSM--PTSTPSEGST 3281
Score = 42.4 bits (98), Expect = 0.002
Identities = 76/363 (20%), Positives = 130/363 (35%), Gaps = 75/363 (20%)
Query: 698 TPVLMKQEHREEIDLSSVPSLPVPHPAQTQRPSSDSGCSHDSVLSGQRSLICSIPQ-TYA 756
TPV + + + PSL P+ P + S V+S + S + + P T
Sbjct: 245 TPVTISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNI 304
Query: 757 SMVTSSHLPQLQCRDESVSKEQHMIPSPIVHQ---PFQVTP--TPPVGSSYQ------PM 805
++TS+ E S IP+ + P TP T PV +S P+
Sbjct: 305 PVITSTEASSSPTTAEGTS-----IPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPV 359
Query: 806 QTNVVYNG---PTCLPINAASSQEFDSVLFQQDATLSGLVNLGCQPLSSIPFHSSNSGST 862
T+ + P+ LP A ++ S L + L+ + P+S+I SS + +T
Sbjct: 360 DTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNM------PVSTILVASSEASTT 413
Query: 863 GHLLAHTPHSVHTLPHLQSMGYHCSNTGQRSLSSPVADQITGQPSSQLQPITYGPSHSGS 922
+ + V T + SSP + T +S PS +
Sbjct: 414 STIPVDSKTFV--------------TTASEASSSPTTAEDTSIATST-------PSEGST 452
Query: 923 ATTASPAASHPLASSPL---------------------SGPPSPQLQPMPYQSPSSGTAS 961
T+ P ++ P+ASS S PP+ ++ MP +PS G+
Sbjct: 453 PLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGS-- 510
Query: 962 SPSPATRMHSGQ---HSTQAQSTGQGGLSAPSSLICHSLCDPASFPPDGATVSIKPEPED 1018
+P T M S++A + + + + S +S P+G ++ E
Sbjct: 511 --TPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEG 568
Query: 1019 REP 1021
P
Sbjct: 569 STP 571
Score = 42.4 bits (98), Expect = 0.002
Identities = 70/341 (20%), Positives = 124/341 (36%), Gaps = 27/341 (7%)
Query: 696 TYTPVLMKQEHREEIDLSSVPSLPVPHPAQTQRPSSDSGCSHDSVLSGQRSLICSIPQTY 755
T TPV E S+P P++ P ++ S V+S + S + P
Sbjct: 538 TSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADS 597
Query: 756 ASMVTSSHLPQLQCRDESVSKEQHMIPSPIVHQ------PFQVTPTPPVGSSYQPMQTNV 809
+ VT+S + S + E +P+ + V+ T S + T
Sbjct: 598 NTFVTTSS----EASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTP 653
Query: 810 VYNGPTCLPINAASSQEFDSVLFQQDATLSGLVNLGCQPLSSIPFHSS-NSGSTGHLLAH 868
V + P+ ++ S + + + G PL+S+P +++ + S L+
Sbjct: 654 VDSN---TPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLST 710
Query: 869 TPHSVHTLPHLQSMGYHCSNTGQRSLSSPVADQITGQPSSQLQPITYGPSHSGSATTAS- 927
TP T P S S T S P + G P++ S A+T S
Sbjct: 711 TPVDTST-PVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLST 769
Query: 928 ---PAASHPLASSPLS-GPPSPQLQPMPYQSPSSGT---ASSPSPATRMHSGQHSTQAQS 980
++H S+ S P + + MP +PS G+ S P T + S + ST + +
Sbjct: 770 TPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTT 829
Query: 981 TGQGGLSAPSSLICHSLCDPASFPPDGATVSIKPEPEDREP 1021
+ + S + + + P +G ++ E R P
Sbjct: 830 P----VDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTP 866
Score = 40.8 bits (94), Expect = 0.007
Identities = 63/293 (21%), Positives = 104/293 (35%), Gaps = 21/293 (7%)
Query: 698 TPVLMKQEHREEIDLSSVPSLPVPHPAQTQRPSSDSGCSHDSVLSGQRSLICSIPQTYAS 757
TPV E R S S+P P++ P + S VLS + S + + P ++
Sbjct: 1719 TPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTST 1778
Query: 758 MVTSSHLPQLQCRDESVSKEQHMIPSPIVHQ---PFQVTP---TPPVGSSYQPMQTNVVY 811
VT+S + + E IP+ + + P TP T S + T V
Sbjct: 1779 PVTTS----TEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVD 1834
Query: 812 NGPTCLPINAASSQEFDSVLFQQDATLSGLVNLGCQPLSSIPFHSSNSGSTGHLLAHTPH 871
+ + A SS + + + + + G L+SIP ++ S+ T
Sbjct: 1835 SNSPVVTSTAVSSSPTPA---EGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTP 1891
Query: 872 SVHTLPHLQSMGYHCSNTGQRSLSSPVADQITGQPSSQLQPITYGPSHSGS--------A 923
+V + P S T S P + G+P P++ S A
Sbjct: 1892 AVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLA 1951
Query: 924 TTASPAASHPLASSPLSGPPSPQLQPMPYQSPSSGTASSPSPATRMHSGQHST 976
T +P ++ ASS + + Y S+ S P T + S + ST
Sbjct: 1952 DTRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEAST 2004
Score = 40.4 bits (93), Expect = 0.009
Identities = 69/350 (19%), Positives = 130/350 (37%), Gaps = 40/350 (11%)
Query: 656 QGAHIVLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTPVLMKQEHREEIDLSSV 715
+G I P +T+ H + N S++ + TPV + SS
Sbjct: 969 EGTSIPTSTPSEGTTPLTSTPVSHTLVAN-----SEASTLSTTPVDSNTPLTTSTEASSP 1023
Query: 716 P------SLPVPHPAQTQRPSSDSGCSHDSVLSGQRSLICSIPQTYASMVTSSHLPQLQC 769
P S+P P++ P + S V S + S + + P ++ VT+ Q
Sbjct: 1024 PPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYS----QA 1079
Query: 770 RDESVSKEQHMIPSPIVHQ---PFQVTPTPP---VGSSYQPMQTNVVYNGPTCLPINAAS 823
S + + +P+ + P P V S + T V T +P+ ++
Sbjct: 1080 SSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPV---DTSIPVTTST 1136
Query: 824 SQEFDSVLFQQDATLSGLVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHSVHTLPHLQSMG 883
+ + + + G PL+S+P ST +++ +++ T P + S
Sbjct: 1137 EASSSPTTAEGTSIPTSPPSEGTTPLASMPV------STTLVVSSEANTLSTTP-VDSKT 1189
Query: 884 YHCSNTGQRSLSSPVADQITGQPSSQLQPITYGPSHSGSATTASPAASHPLASSPLSGPP 943
++T + S P ++T P+S P + T+ P P+ASS S
Sbjct: 1190 QVATST--EASSPPPTAEVTSMPTST-------PGERSTPLTSMPVRHTPVASSEASTLS 1240
Query: 944 SPQLQPMPYQSPSSGTASSPSPATRMHSGQHSTQAQSTGQGGLSAPSSLI 993
+ + + S+ T+SSP+ A +T ST + ++L+
Sbjct: 1241 TSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLV 1290
Score = 40.0 bits (92), Expect = 0.012
Identities = 73/345 (21%), Positives = 125/345 (36%), Gaps = 46/345 (13%)
Query: 696 TYTPVLMKQEHREEIDLSSVPSLPVPHPAQTQRPSSDSGCSHDSVLSGQRSLICSIPQTY 755
T TPV E R S S+P P++ P + S V++ + S + + P
Sbjct: 2188 TSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDT 2247
Query: 756 ASMVTSSHLPQLQCRDESVSKEQHMIPS-------------PIVH-----QPFQVTPTPP 797
++ VT+S + + E IP+ P+ H T P
Sbjct: 2248 STPVTTS----TEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTP 2303
Query: 798 VGSSYQPMQTNVVYNGP------TCLPINAASSQEFDSVLFQQDATLSGLVNLGCQPLSS 851
V S+ P T+ + P T +P ++S E ++ L + + + + + LS+
Sbjct: 2304 VDSN-TPFTTSTEASSPPPTAEGTSMP--TSTSSEGNTPLTRMPVSTTMVASFETSTLST 2360
Query: 852 IPFHSSNSGSTGHLLAHTPHSVHTLPHLQSMGYHCSNTGQRSLSSPVADQITGQPSSQLQ 911
P +S +T +P T SM + G L+S + S
Sbjct: 2361 TPADTSTPVTTYSQAGSSP----TTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEAST 2416
Query: 912 PITYGPSHSGSATTASPAASHPLASSPLSGPPSPQLQPMPYQSPSSGTASSPSPATRMHS 971
T S TT++ A+S P + S P SP P +P + S +P +
Sbjct: 2417 HSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSP---PSEGTTPLASMPVSTTPVVSSEA 2473
Query: 972 GQHST------QAQSTGQGGLSAPSSLICHSLCDPASFPPDGATV 1010
G ST +T S+P++ + P S +G+T+
Sbjct: 2474 GTLSTTPVDTSTPMTTSTEASSSPTT--AEDIVVPISTASEGSTL 2516
Score = 39.3 bits (90), Expect = 0.020
Identities = 79/337 (23%), Positives = 118/337 (35%), Gaps = 36/337 (10%)
Query: 696 TYTPVLMKQEHREEIDLSSVPSLPVPHPAQTQRPSSDSGCSHDSVLSGQRSLICSIPQTY 755
T TPV E R S S+P P + P + S V+S + + + P
Sbjct: 892 TSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDT 951
Query: 756 ASMVTSSHLPQLQCRDESVSKEQHMIP--------SPIVHQPFQVTPTPPVGSSYQPMQT 807
++ VT+S + + E IP +P+ P V+ T S + T
Sbjct: 952 STPVTTS----TEATSSPTTAEGTSIPTSTPSEGTTPLTSTP--VSHTLVANSEASTLST 1005
Query: 808 NVV-YNGPTCLPINAASSQEFDSVLFQQDATLS-GLVNLGCQPLSSIPFHSSNSGSTGHL 865
V N P A+S +T S G L P+S+ SS + +
Sbjct: 1006 TPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTT 1065
Query: 866 LAHTPHSVHTLPHLQSMGYHCSNTGQRSLSSPVADQITGQPSSQLQPITYGPSHSGSATT 925
A T V T S S+T S P + G P++ S A+T
Sbjct: 1066 PADTSTPVTTYSQASS-----SSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEAST 1120
Query: 926 ASPA---ASHPLASS--PLSGPPSPQLQPMPYQSPSSGT---ASSPSPATRMHSGQHSTQ 977
S S P+ +S S P + + +P PS GT AS P T + S + +T
Sbjct: 1121 LSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTL 1180
Query: 978 AQSTGQGGLSAPSSLICHSLCDPASFPPDGATVSIKP 1014
+ + +S AS PP A V+ P
Sbjct: 1181 STTPVDSKTQVATS-------TEASSPPPTAEVTSMP 1210
Score = 37.7 bits (86), Expect = 0.058
Identities = 62/323 (19%), Positives = 117/323 (36%), Gaps = 29/323 (8%)
Query: 696 TYTPVLMKQEHREEIDLSSVPSLPVPHPAQTQRPSSDSGCSHDSVLSGQRSLICSIPQTY 755
T PV+ E + S+P + P + + S V + + S + P
Sbjct: 302 TNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDT 361
Query: 756 ASMVTSSHLP-QLQCRDESVSKEQHMI---PSPIVHQPF----------QVTPTPPVGSS 801
+++VT+S P L E+ S + +P+ + P T T PV S
Sbjct: 362 STLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSK 421
Query: 802 YQPMQTNVVYNGPTC---LPINAASSQEFDSVLFQQDATLSGLVNLGCQPLSSIPFHSSN 858
+ + PT I ++ E + L + + + + LS+ P S
Sbjct: 422 TFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKT 481
Query: 859 SGSTGHLLAHTPHSVH------TLPHLQSMGYHCSNTGQRSLSSPVADQITGQPSSQLQP 912
+T + +P + + P S + ++S A ++ P P
Sbjct: 482 QVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTP 541
Query: 913 ITYGPSHSGSAT----TASPAASHPLASSPLSGPPSPQLQPMPYQSPSSGTASSPSPATR 968
+T S S+T T+ P ++ S+PL+ P + S +S T+++P+ +
Sbjct: 542 VTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTN--MPVSTRLVVSSEASTTSTTPADSNT 599
Query: 969 MHSGQHSTQAQSTGQGGLSAPSS 991
+ + ST G S P+S
Sbjct: 600 FVTTSSEASSSSTTAEGTSMPTS 622
Score = 36.2 bits (82), Expect = 0.17
Identities = 61/318 (19%), Positives = 117/318 (36%), Gaps = 33/318 (10%)
Query: 696 TYTPVLMKQEHREEIDLSSVPSLPVPHPAQTQRPSSDSGCSHDSVLSGQRSLICSIP-QT 754
T TPV E + S+P ++ P + + SH V + + S + + P +
Sbjct: 1776 TSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDS 1835
Query: 755 YASMVTSSHLPQLQCRDESVSKEQHMIPSPIVHQPFQVTPTPPVGSSYQPMQTNVVYNGP 814
+ +VTS+ + E S + S +T P ++ +TN + P
Sbjct: 1836 NSPVVTSTAVSSSPTPAEGTS----IATSTPSEGSTALTSIPVSTTTVASSETNTLSTTP 1891
Query: 815 --TCLPINAASSQEFDSVLFQQDATLSGLVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHS 872
T P+ + + + G PL+SIP ++ S+
Sbjct: 1892 AVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASS---------E 1942
Query: 873 VHTLPHLQSMGYHCSNTGQRSLSSPVADQITGQPSSQLQPITYGPSHSGSATTASPAASH 932
++TL + T ++ SSP T P+ P++S +T P S
Sbjct: 1943 INTLSTTLADTRTPVTTYSQASSSPTTADGTSMPT---------PAYSEGST---PLTSM 1990
Query: 933 PLASSPLSGPPSPQLQPMPYQSPSSGTASSPSPATRMHSGQHSTQA-----QSTGQGGLS 987
PL+++ + + L P + + T S+ ++ +G S Q ++T G+
Sbjct: 1991 PLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMP 2050
Query: 988 APSSLICHSLCDPASFPP 1005
++L+ S + S P
Sbjct: 2051 VSTTLVVSSEGNTLSTTP 2068
Score = 35.4 bits (80), Expect = 0.29
Identities = 77/352 (21%), Positives = 123/352 (34%), Gaps = 73/352 (20%)
Query: 696 TYTPVLMKQEHREEIDLSSVPSLPVPHPAQTQRPSSDSGCSHDSVLSGQRSLICSIPQTY 755
T TPV + V S+P + P ++ S V S + S + + P
Sbjct: 3485 TSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDS 3544
Query: 756 ASMVTSSHLPQLQCRDESVSKEQHMIPSPIVHQPFQVTPTPPVGSSYQPMQTNVVYNGPT 815
+ VTS S + P+ + +++ TP GSS + T
Sbjct: 3545 NTFVTS-------------SSQASSSPATLQVTTMRMS-TPSEGSS----SLTTMLLSST 3586
Query: 816 CLPINAASSQEFDSVLFQQDATLSGLVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHSVHT 875
+ + AS+ SV T S+ S ST TP V T
Sbjct: 3587 YVTSSEASTPSTPSVDRSTPVTT-----------------STQSNST-----PTPPEVIT 3624
Query: 876 LPHLQSMGYHCSNTGQRSLSSPVADQITGQPSSQLQPITYGPSHSGSATTASPAASHPLA 935
LP S S V+ +T P S S +G+A+T S P+
Sbjct: 3625 LP--------------MSTPSEVSTPLTIMPVSTTSVTI---SEAGTASTLPVDTSTPVI 3667
Query: 936 SSP--LSGPPSPQLQPMPYQSPSSGT---ASSPSPATRMHSGQHSTQAQ---------ST 981
+S S P +P+ MP +PS G+ + P TR+ S + ST + +T
Sbjct: 3668 TSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTT 3727
Query: 982 GQGGLSAPSSL--ICHSLCDPASFPPDGATVSIKPEPEDREPNFATIGLQDI 1031
+S+ ++L S+ P G T+ + P R P +T + +
Sbjct: 3728 STEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSV 3779
Score = 32.7 bits (73), Expect = 1.9
Identities = 74/341 (21%), Positives = 116/341 (34%), Gaps = 29/341 (8%)
Query: 696 TYTPVLMKQEHREEIDLSSVPSLPVPHPAQTQRPSSDSGCSHDSVLSGQRSLICSIPQTY 755
T TP E + S+ P++ P + S V+S + + + + P
Sbjct: 2012 TSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDS 2071
Query: 756 ASMVTSSHLPQLQCRDESVSKEQHMIPSPIVHQPF----QVTPTPPVGSSYQPMQTNVV- 810
+ VT+S E S I +P P ++ TP + T V
Sbjct: 2072 KTQVTNSTEASSSATAEGSSMT---ISAPSEGSPLLTSIPLSTTPVASPEASTLSTTPVD 2128
Query: 811 YNGPTCLPINAASSQEFDSVLFQQDATLSGLVNLGCQPLSSIPFHSSNSGSTG-HLLAHT 869
N P +SS Q +T S PL+S+P ++ S+ L+ T
Sbjct: 2129 SNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRT----PLTSMPVSTTVVASSAISTLSTT 2184
Query: 870 PHSVHTLPHLQSMGYHCSNTGQRSLSSPVADQITGQPSSQLQPITYGPSHSGSATTASPA 929
P T P S S T S P + G P++ P + A+T S
Sbjct: 2185 PVDTST-PVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSAT 2243
Query: 930 ---ASHPLASS--PLSGPPSPQLQPMPYQSPSSGT---ASSPSPATRMHSGQHSTQAQST 981
S P+ +S S P + + +P + S GT S P T + + + ST + +
Sbjct: 2244 PVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTP 2303
Query: 982 GQGGLSAPSSLICHSLCDPASFPPDGATVSIKPEPEDREPN 1022
+S AS PP A + P E N
Sbjct: 2304 VDSNTPFTTS-------TEASSPPPTAEGTSMPTSTSSEGN 2337
Score = 32.3 bits (72), Expect = 2.4
Identities = 37/151 (24%), Positives = 62/151 (41%), Gaps = 15/151 (9%)
Query: 817 LPINAASSQEF--DSVLFQQDATLS--GLVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHS 872
LP AA+ Q+ + ++ +S ++N CQ LS +GS + T +
Sbjct: 19 LPPQAAAEQDLSVNRAVWDGGGCISQGDVLNRQCQQLSQ----HVRTGSAANTATGTTST 74
Query: 873 VHTLPHLQSMGYHCS-NTGQRSLSSPVADQITGQPSSQLQPITYGPSHSGSATTASPAAS 931
P M CS N S+ S V G S+++ P S + S +T+
Sbjct: 75 NVVEPR---MYLSCSTNPEMTSIESSVTSDTPGVSSTRMTPTE---SRTTSESTSDSTTL 128
Query: 932 HPLASSPLSGPPSPQLQPMPYQSPSSGTASS 962
P ++ S P +P+ +P +PS + SS
Sbjct: 129 FPSSTEDTSSPTTPEGTDVPMSTPSEESISS 159
>gi|112382214 SEC24 (S. cerevisiae) homolog B isoform b [Homo sapiens]
Length = 1233
Score = 52.4 bits (124), Expect = 2e-06
Identities = 72/299 (24%), Positives = 111/299 (37%), Gaps = 32/299 (10%)
Query: 736 SHDSVLSGQRSLICSIPQTYASMVTSSHLPQLQCRDESVSKEQHMIPSPIVHQPFQVT-- 793
S S L S Q Y+S V + P + SV+ + PS H
Sbjct: 133 SFQGAASSASHLHTSASQPYSSFVNHYNSPAMYSASSSVASQG--FPSTCGHYAMSTVSN 190
Query: 794 --------PTPPVGSSYQPMQTNVVYNGPTCLPI--NAASSQEFDSVLFQQDATLSGLVN 843
P+ P G +Y M T+ N PT P+ N+ S Q + + L L +
Sbjct: 191 AAYPSVSYPSLPAGDTYGQMFTS--QNAPTVRPVKDNSFSGQ---NTAISHPSPLPPLPS 245
Query: 844 LGCQPLSSIPFHSSNSGSTGHLLAHTPHSVHTLPHLQSMGYHCSN---TGQRSLSSPVAD 900
S+ +S+ + S+ L + + + H S+ +N T SLS PV
Sbjct: 246 QQHHQQQSLSGYSTLTWSSPGLPSTQDNLIRN--HTGSLAVANNNPTITVADSLSCPVMQ 303
Query: 901 QITGQPSSQLQPITYGPSHSGSATTASPAASHPLASSPLSGPPSPQLQPMPYQSPSSGTA 960
+ SS + S S+T P A+HP+ PS LQ S S+ ++
Sbjct: 304 NVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQQKGVDSSSTTSS 363
Query: 961 SSPSPAT--RMHSGQHSTQAQSTGQGGLSAPSSLICHSLCDPASFP-PDGATVSIKPEP 1016
+SP P + + G + S+ P+ DPAS P P A + P+P
Sbjct: 364 ASPMPNSYDALEGGSYPDMLSSSASSPAPDPA-----PEPDPASAPAPASAPAPVVPQP 417
>gi|58530876 melanoma antigen family C, 1 [Homo sapiens]
Length = 1142
Score = 45.8 bits (107), Expect = 2e-04
Identities = 69/270 (25%), Positives = 97/270 (35%), Gaps = 26/270 (9%)
Query: 752 PQTYASMVTSSHLPQLQCRDESVSKEQHMIPSPIVHQPFQVTPTPPVGS-SYQPMQTNVV 810
P + S T S LPQ S + P V P +PP G S P+Q+
Sbjct: 628 PVSICSSSTPSSLPQ------SFPESSQSPPEGPVQSPLHSPQSPPEGMHSQSPLQS--- 678
Query: 811 YNGPTCLPINAASSQEFDSVLFQQDATLSGLVNLGCQPLSSIPFHSSNSGSTGHLLAHTP 870
P +A ++ S L + L G +L P +S S H P
Sbjct: 679 -------PESAPEGEDSLSPLQIPQSPLEGEDSLSSLHFPQSPPEWEDSLSPLHFPQFPP 731
Query: 871 HSVHTLPHLQSMGYHCSNTGQRSLSSPVADQITGQPSSQLQ-PITYGPSHSGSATTASPA 929
LQS CS++ SL + P Q P+ S S T AS
Sbjct: 732 QGEDFQSSLQSPVSICSSSTSLSLPQSFPESPQSPPEGPAQSPLQRPVSSFFSYTLASLL 791
Query: 930 -ASHPLASSPLSGPPSPQLQP--MPYQSPSSGTASSPSPATRMHSGQHSTQAQSTGQGGL 986
+SH SP GP LQ + S +S + S SP + S S+ ++S+ + L
Sbjct: 792 QSSHESPQSPPEGPAQSPLQSPVSSFPSSTSSSLSQSSPVSSFPSSTSSSLSKSSPESPL 851
Query: 987 SAP-----SSLICHSLCDPASFPPDGATVS 1011
+P SS + +S P D T S
Sbjct: 852 QSPVISFSSSTSLSPFSEESSSPVDEYTSS 881
Score = 42.0 bits (97), Expect = 0.003
Identities = 84/316 (26%), Positives = 102/316 (32%), Gaps = 66/316 (20%)
Query: 24 PAPPPPGSR-------PADLEPDDCASIYIFNVDPPPSTLT-TPLCLPHHGLPSH---SS 72
P PP G P + +D S + F PP + +PL P L SS
Sbjct: 565 PQSPPQGEDSLSPHYFPQSPQGEDSLSPHYFPQSPPQGEDSMSPLYFPQSPLQGEEFQSS 624
Query: 73 VLSPSFQLQSHKNYEGTCEIPESKYSPLGGP---------KPFECPSIQITSISPNCHQE 123
+ SP S PES SP GP P E Q SP E
Sbjct: 625 LQSPVSICSSSTPSSLPQSFPESSQSPPEGPVQSPLHSPQSPPEGMHSQSPLQSPESAPE 684
Query: 124 LDAHEDDLQINDPEREFLERPSRDHLYLPLEPSYRESSLSPSP-----------ASSISS 172
+ LQI P+ S L+ P P E SLSP SS+ S
Sbjct: 685 GEDSLSPLQI--PQSPLEGEDSLSSLHFPQSPPEWEDSLSPLHFPQFPPQGEDFQSSLQS 742
Query: 173 RSWFSDASSCESLSHIYDDVDSELNEAAAR------------FTLGSPLTSPGGSPGGCP 220
+S+ SL + + E A+ +TL S L S SP P
Sbjct: 743 PVSICSSSTSLSLPQSFPESPQSPPEGPAQSPLQRPVSSFFSYTLASLLQSSHESPQSPP 802
Query: 221 GEETWHQQYGLGHSLSPRQSPCHSPRSSVTDENWLSPRPASGPSSRPTSPCGKRRHSSAE 280
P QSP SP SS S +S SS P+S SS E
Sbjct: 803 E--------------GPAQSPLQSPVSSFPSSTSSSLSQSSPVSSFPSSTSSSLSKSSPE 848
Query: 281 VCYAGSLSPHHSPVPS 296
SP SPV S
Sbjct: 849 -------SPLQSPVIS 857
Score = 30.4 bits (67), Expect = 9.3
Identities = 69/259 (26%), Positives = 95/259 (36%), Gaps = 49/259 (18%)
Query: 58 TPLCLPHHGLPSHSSV-LSPSFQLQSHKNYEGTCEIPESKYSPLGGPKPFECPSIQITSI 116
+PL +P S++ + L S ++H +EG P+S PL P S + S+
Sbjct: 441 SPLQIPVSSSFSYTLLSLFQSSPERTHSTFEG---FPQS---PLQIPVSSSSSSSTLLSL 494
Query: 117 ---SPNCHQEL--DAHEDDLQI--NDPEREFLERPSRDHLYLPLEPSYRESSLSPSPASS 169
SP C Q + LQI + PE E P L + PS E S SP
Sbjct: 495 FQSSPECTQSTFEGFPQSPLQIPQSPPEGENTHSP------LQIVPSLPEWEDSLSPHYF 548
Query: 170 ISSRSWFSDASSCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCPGEETWHQQY 229
S D+ S H + + G SP P GE++ Y
Sbjct: 549 PQSPPQGEDSLS----PHYFPQSPPQ----------GEDSLSPHYFPQSPQGEDSLSPHY 594
Query: 230 GLGHSLSPRQ-----SPCHSPRSSVTDENWLSPRPASGPSSRPTSPCGKRRHSSAEVCYA 284
SP Q SP + P+S + E + S + P S C SS +
Sbjct: 595 ---FPQSPPQGEDSMSPLYFPQSPLQGEEFQSSLQS------PVSICSSSTPSSLPQSFP 645
Query: 285 -GSLSPHHSPVPSPGHSPR 302
S SP PV SP HSP+
Sbjct: 646 ESSQSPPEGPVQSPLHSPQ 664
>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
Length = 1970
Score = 45.4 bits (106), Expect = 3e-04
Identities = 48/158 (30%), Positives = 67/158 (42%), Gaps = 14/158 (8%)
Query: 150 YLPLEPSYRESSLSPSPAS---SISSRSWFSDASSCESLSHIYDDVDSELNEAAARFTLG 206
Y P PSY +S S SP S S +S S+ + S S Y + + ++
Sbjct: 1650 YSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPT 1709
Query: 207 SPLTSPGGSPGGCPGEETWHQQYGLGHSLSPRQSPCHSPRSSVTDENWLSPRPA---SGP 263
SP SP SP P ++ SP SP SP S T N+ P+ + P
Sbjct: 1710 SPSYSPT-SPSYSPTSPSYSPTSPSYSPTSPSYSPT-SPNYSPTSPNYTPTSPSYSPTSP 1767
Query: 264 SSRPTSPCGKRRHSSAEVCYAGSLSPHHSPVPSPGHSP 301
S PTSP ++ Y+ + SP +SP SP +SP
Sbjct: 1768 SYSPTSP----NYTPTSPNYSPT-SPSYSPT-SPSYSP 1799
Score = 43.1 bits (100), Expect = 0.001
Identities = 47/163 (28%), Positives = 70/163 (42%), Gaps = 15/163 (9%)
Query: 150 YLPLEPSYRESSLSPSPAS---SISSRSWFSDASSCESLSHIYDDVDSELNEAAARFTLG 206
Y P PSY +S S SP S + +S ++ + S S Y + ++ R+T
Sbjct: 1755 YTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQ 1814
Query: 207 SPLTSPGGSPGGCPGEETWHQQYGLGHSLSPRQSPCHSPRSSVTDENWLSPRPASGPSSR 266
SP +P SP P ++ SP SP SP + T + SP + P
Sbjct: 1815 SPTYTP-SSPSYSPSSPSYSPTSPKYTPTSPSYSP-SSPEYTPTSPKY-SP---TSPKYS 1868
Query: 267 PTSPCGKRRHSSAEVCYAGSLSPHHSPVPSPGHSPRGSVTEDT 309
PTSP ++S Y+ + +P +SP SP +SP V T
Sbjct: 1869 PTSP----KYSPTSPTYSPT-TPKYSPT-SPTYSPTSPVYTPT 1905
Score = 42.7 bits (99), Expect = 0.002
Identities = 46/158 (29%), Positives = 68/158 (43%), Gaps = 14/158 (8%)
Query: 150 YLPLEPSYRESSLSPSPAS---SISSRSWFSDASSCESLSHIYDDVDSELNEAAARFTLG 206
Y P PSY +S S SP S S +S ++ + S S Y + + ++
Sbjct: 1608 YTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPT 1667
Query: 207 SPLTSPGGSPGGCPGEETWHQQYGLGHSLSPRQSPCHSPRSSVTDENWLSPRPA---SGP 263
SP SP SP P ++ SP SP SP S T ++ P+ + P
Sbjct: 1668 SPSYSP-TSPSYSPTSPSYSPTSPSYSPTSPSYSPT-SPSYSPTSPSYSPTSPSYSPTSP 1725
Query: 264 SSRPTSPCGKRRHSSAEVCYAGSLSPHHSPVPSPGHSP 301
S PTSP +S Y+ + SP++SP SP ++P
Sbjct: 1726 SYSPTSP----SYSPTSPSYSPT-SPNYSPT-SPNYTP 1757
Score = 40.4 bits (93), Expect = 0.009
Identities = 49/162 (30%), Positives = 72/162 (44%), Gaps = 12/162 (7%)
Query: 150 YLPLEPSYRESSLSPSPAS---SISSRSWFSDASSCESLSHIYDDVDSELNEAAARFTLG 206
Y P PSY SS S SP S + +S S+ + S Y + + + +++
Sbjct: 1818 YTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPT 1877
Query: 207 SPLTSPGGSPGGCPGEETWHQQYGLGHSLSPRQSPCHSPRSSVTDENWLSPRPASGPSSR 266
SP SP +P P T+ + SP+ SP SP S T + SP + P+
Sbjct: 1878 SPTYSP-TTPKYSPTSPTYSPTSPVYTPTSPKYSPT-SPTYSPTSPKY-SP---TSPTYS 1931
Query: 267 PTSPCGKRRHSSAEVCYAGSLSPHHSPVPSPGHSPRGSVTED 308
PTSP G +S Y+ + SP +S + SP SP S E+
Sbjct: 1932 PTSPKGS-TYSPTSPGYSPT-SPTYS-LTSPAISPDDSDEEN 1970
Score = 36.2 bits (82), Expect = 0.17
Identities = 28/109 (25%), Positives = 45/109 (41%), Gaps = 1/109 (0%)
Query: 917 PSHSGSATTASPAASHPLASSPLSGPPSPQLQPM-PYQSPSSGTASSPSPATRMHSGQHS 975
PS+S ++ + SP + +SP P SP P P SP+S + S SP+ S +S
Sbjct: 1641 PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS 1700
Query: 976 TQAQSTGQGGLSAPSSLICHSLCDPASFPPDGATVSIKPEPEDREPNFA 1024
+ S S + +S P+ P + P PN++
Sbjct: 1701 PTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYS 1749
Score = 36.2 bits (82), Expect = 0.17
Identities = 31/109 (28%), Positives = 49/109 (44%), Gaps = 8/109 (7%)
Query: 917 PSHSGSATTASPAASHPLASSPLSGPPSPQLQPMPYQSPS-SGTASSPSPATRMHSGQHS 975
PS+S ++ + SP + + +SP P SP P SPS S T+ S SP++ ++ Q
Sbjct: 1760 PSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSP---TSPSYSPTSPSYSPSSPRYTPQSP 1816
Query: 976 TQAQSTGQGGLSAPSSLICHSLCDPASFPPDGATVSIKPEPEDREPNFA 1024
T S+ S+PS +S P P + PE P ++
Sbjct: 1817 TYTPSSPSYSPSSPS----YSPTSPKYTPTSPSYSPSSPEYTPTSPKYS 1861
Score = 35.4 bits (80), Expect = 0.29
Identities = 55/222 (24%), Positives = 79/222 (35%), Gaps = 20/222 (9%)
Query: 793 TPTPPVGS----SYQPMQTNVVYNGPTCLPINAASSQEFDSVLFQQDATLSGLVNLGCQP 848
TPT P S SY P N P P + + S S + Q
Sbjct: 1756 TPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQS 1815
Query: 849 LSSIPFHSSNSGSTGHLLAHTPHSVHTLPHLQSMGYHCSNTGQRSLSSPVADQITGQPSS 908
+ P S S S+ +P T P + T + + T S
Sbjct: 1816 PTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSPKYS 1875
Query: 909 QLQPITYGPS---HSGSATTASPAASHPLASSPLSGPPSPQLQP-MPYQSPSSGTASSPS 964
P TY P+ +S ++ T SP + +SP P SP P P SP+S T S S
Sbjct: 1876 PTSP-TYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSPTS 1934
Query: 965 PATRMHSGQHSTQAQSTGQGGLSAPSSLICHSLCDPASFPPD 1006
P + ST + ++ ++P+ +SL PA P D
Sbjct: 1935 P-------KGSTYSPTSPGYSPTSPT----YSLTSPAISPDD 1965
Score = 35.0 bits (79), Expect = 0.38
Identities = 27/109 (24%), Positives = 46/109 (42%), Gaps = 1/109 (0%)
Query: 917 PSHSGSATTASPAASHPLASSPLSGPPSPQLQP-MPYQSPSSGTASSPSPATRMHSGQHS 975
PS+S ++ + SP + + +SP P SP P P SP+S + S SP+ S +S
Sbjct: 1620 PSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS 1679
Query: 976 TQAQSTGQGGLSAPSSLICHSLCDPASFPPDGATVSIKPEPEDREPNFA 1024
+ S S + +S P+ P + P P+++
Sbjct: 1680 PTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS 1728
Score = 33.9 bits (76), Expect = 0.84
Identities = 27/109 (24%), Positives = 45/109 (41%), Gaps = 1/109 (0%)
Query: 917 PSHSGSATTASPAASHPLASSPLSGPPSPQLQP-MPYQSPSSGTASSPSPATRMHSGQHS 975
PS+S ++ + SP + +SP P SP P P SP+S + S SP+ S +S
Sbjct: 1613 PSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS 1672
Query: 976 TQAQSTGQGGLSAPSSLICHSLCDPASFPPDGATVSIKPEPEDREPNFA 1024
+ S S + +S P+ P + P P+++
Sbjct: 1673 PTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS 1721
Score = 33.1 bits (74), Expect = 1.4
Identities = 53/235 (22%), Positives = 83/235 (35%), Gaps = 11/235 (4%)
Query: 797 PVGSSYQPMQTNVVYNGPTCLPINAASSQEFDSVLFQQDATLSGLVNLGCQPLSSIPFHS 856
P SY P + P+ P + + S S + N + P
Sbjct: 1701 PTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSP 1760
Query: 857 SNSGSTGHLLAHTPHSVHTLPHLQSMGYHCSNTGQRSLSSPVADQITGQPSSQLQPITY- 915
S S ++ +P+ T P+ S T S S P Q TY
Sbjct: 1761 SYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSP-SYSPTSPSYSPSSPRYTPQSPTYT 1819
Query: 916 --GPSHSGSATTASPAASHPLASSPLSGPPSPQLQP-MPYQSPSSGTASSPSPATRMHSG 972
PS+S S+ + SP + +SP P SP+ P P SP+S S SP +S
Sbjct: 1820 PSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSP---KYSP 1876
Query: 973 QHSTQAQSTGQGGLSAPSSLICHSLCDPAS--FPPDGATVS-IKPEPEDREPNFA 1024
T + +T + ++P+ + P S + P T S P+ P ++
Sbjct: 1877 TSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPTSPTYSPTSPKYSPTSPTYS 1931
Score = 31.6 bits (70), Expect = 4.2
Identities = 40/142 (28%), Positives = 53/142 (37%), Gaps = 19/142 (13%)
Query: 163 SPSPASSISSRSWFSDASSCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCPGE 222
+PSP IS + + + V S + AA F+ + + G SPG P
Sbjct: 1506 APSPMGGISPAMTPWNQGATPAYGAWSPSVGSGMTPGAAGFSPSAASDASGFSPGYSPA- 1564
Query: 223 ETWHQQYGLGHSLSPRQSPCHSPRSSVTDENWLSPRPASGPSSRPTSPCGKRRHSSAEVC 282
W G S P S + P SP A PS PTSP + R
Sbjct: 1565 --WSPTPGSPGSPGP--SSPYIP----------SPGGAMSPSYSPTSPAYEPRSPGGYTP 1610
Query: 283 YAGS---LSPHHSPVPSPGHSP 301
+ S SP +SP SP +SP
Sbjct: 1611 QSPSYSPTSPSYSPT-SPSYSP 1631
Score = 31.6 bits (70), Expect = 4.2
Identities = 25/109 (22%), Positives = 44/109 (40%), Gaps = 1/109 (0%)
Query: 917 PSHSGSATTASPAASHPLASSPLSGPPSPQLQP-MPYQSPSSGTASSPSPATRMHSGQHS 975
PS+S ++ + SP + +SP P SP P P SP+S + S SP+ S +S
Sbjct: 1683 PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS 1742
Query: 976 TQAQSTGQGGLSAPSSLICHSLCDPASFPPDGATVSIKPEPEDREPNFA 1024
+ + + + +S P+ P P P+++
Sbjct: 1743 PTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYS 1791
>gi|28558973 mediator complex subunit 14 [Homo sapiens]
Length = 1454
Score = 45.4 bits (106), Expect = 3e-04
Identities = 44/142 (30%), Positives = 55/142 (38%), Gaps = 35/142 (24%)
Query: 943 PSPQLQPMPYQSPSSGTASSPSPATRMHSGQHST------------QAQSTGQGGLSAPS 990
P PQ QP P Q +SG SP T HS + + A S+ G L APS
Sbjct: 1002 PPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPGNLHAASSPSGALRAPS 1061
Query: 991 SLICHSLCDPASF----PPDGATVSIKPEPEDREPNFATIGLQDITLDDDQFISDLEHQP 1046
PASF PP +SI P P+ TLD + + P
Sbjct: 1062 ---------PASFVPTPPPSSHGISIGPGASFASPHG--------TLDPSSPYTMV--SP 1102
Query: 1047 SGSAEKWPNHSVLSCPAPFWRI 1068
SG A WP +S P+P R+
Sbjct: 1103 SGRAGNWPGSPQVSGPSPAARM 1124
Score = 30.8 bits (68), Expect = 7.1
Identities = 47/194 (24%), Positives = 66/194 (34%), Gaps = 27/194 (13%)
Query: 117 SPNCHQELDAHEDDLQINDPEREFLERPSRDHLY-LPLEPSYRESSLSPSPASSISSRSW 175
SP +D+ LQ ++ F ++P Y L P+ S+++ SP+ +
Sbjct: 986 SPIGGDMMDSLISQLQPPPQQQPFPKQPGTSGAYPLTSPPTSYHSTVNQSPSMMHTQSPG 1045
Query: 176 FSDASSCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPGGCPGEETWHQQYGLGHSL 235
A+S S + + A F P +S G S G PG + H
Sbjct: 1046 NLHAASSPS--------GALRAPSPASFVPTPPPSSHGISIG--PGAS-----FASPHGT 1090
Query: 236 SPRQSPCHSPRSSVTDENWLSPRPASGPSSRPTSPCGKRRHSSAEVCYAGSLSPHHSPVP 295
SP S NW SGPS P + S HSPVP
Sbjct: 1091 LDPSSPYTMVSPSGRAGNWPGSPQVSGPSPAARMPGMSPANPSL-----------HSPVP 1139
Query: 296 SPGHSPRGSVTEDT 309
HSPR + T
Sbjct: 1140 DASHSPRAGTSSQT 1153
Score = 30.8 bits (68), Expect = 7.1
Identities = 33/114 (28%), Positives = 47/114 (41%), Gaps = 9/114 (7%)
Query: 855 HSSNSGSTGHLLAHTPHSVHTLPHLQSMGYHCSNTGQRSLSSPVADQITGQPSSQLQPIT 914
H+++S S G L A +P S P S G S +SP P + + P
Sbjct: 1048 HAASSPS-GALRAPSPASFVPTPPPSSHGISIGPGA--SFASPHGTLDPSSPYTMVSPSG 1104
Query: 915 YGPSHSGSATTASPAASHPLASSPLSGPPSPQLQ-PMP--YQSPSSGTASSPSP 965
+ GS + P+ P A P P +P L P+P SP +GT+S P
Sbjct: 1105 RAGNWPGSPQVSGPS---PAARMPGMSPANPSLHSPVPDASHSPRAGTSSQTMP 1155
>gi|119943102 CREB binding protein isoform b [Homo sapiens]
Length = 2404
Score = 45.1 bits (105), Expect = 4e-04
Identities = 36/111 (32%), Positives = 47/111 (42%), Gaps = 7/111 (6%)
Query: 880 QSMGYHCSNTGQRSLSSPVADQITGQP-SSQLQPITYGPSHSGSATTASPAASHPLASSP 938
Q M + GQ + SP ++GQP +S L S S + +P S S P
Sbjct: 2261 QQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQP 2320
Query: 939 LSGPPSPQLQPMPYQSPSSGTASSPSPATRMHSGQHSTQAQSTGQGGLSAP 989
PSP++QP P SP + + SP H G T A S QG L P
Sbjct: 2321 PHSSPSPRIQPQP--SPHHVSPQTGSP----HPGLAVTMASSIDQGHLGNP 2365
Score = 39.7 bits (91), Expect = 0.015
Identities = 66/258 (25%), Positives = 96/258 (37%), Gaps = 36/258 (13%)
Query: 796 PPVGSSYQPMQTNVVYNGPTCLPINAASSQEFDSVLFQQDATLSGLVNLGCQPLSSIPF- 854
PPV QP++ NGP LP+N + + L P ++ P
Sbjct: 654 PPVIPQAQPVRPP---NGPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMN 710
Query: 855 HSSNSGSTGHL--LAHTPHSVHTLPHLQSMGYHCSNT-GQRSLSSPVADQITGQPSSQLQ 911
HS S G + +A +P + P++ MG H +N Q S Q SS
Sbjct: 711 HSVQMNSMGSVPGMAISPSRMPQPPNM--MGAHTNNMMAQAPAQSQFLPQNQFPSSSGAM 768
Query: 912 PITYG--PSHSGSATTASPAASHPLASSPLS--GPPSPQLQPMPY-QSPSSGTASSPSPA 966
+ G P+ +G + P A+ P +PL+ GP + QL P QSP T S A
Sbjct: 769 SVGMGQPPAQTGVSQGQVPGAALP---NPLNMLGPQASQLPCPPVTQSPLHPTPPPASTA 825
Query: 967 TRMHSGQH-----------------STQAQSTGQGGLSAPSSLICHSLCDPASFPPDGAT 1009
M S QH ST S+GQ P S+ + A
Sbjct: 826 AGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQ 885
Query: 1010 VSIKPEPED--REPNFAT 1025
+ P+P+ + P+ AT
Sbjct: 886 AQVTPQPQTPVQPPSVAT 903
>gi|119943104 CREB binding protein isoform a [Homo sapiens]
Length = 2442
Score = 45.1 bits (105), Expect = 4e-04
Identities = 36/111 (32%), Positives = 47/111 (42%), Gaps = 7/111 (6%)
Query: 880 QSMGYHCSNTGQRSLSSPVADQITGQP-SSQLQPITYGPSHSGSATTASPAASHPLASSP 938
Q M + GQ + SP ++GQP +S L S S + +P S S P
Sbjct: 2299 QQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQP 2358
Query: 939 LSGPPSPQLQPMPYQSPSSGTASSPSPATRMHSGQHSTQAQSTGQGGLSAP 989
PSP++QP P SP + + SP H G T A S QG L P
Sbjct: 2359 PHSSPSPRIQPQP--SPHHVSPQTGSP----HPGLAVTMASSIDQGHLGNP 2403
Score = 39.7 bits (91), Expect = 0.015
Identities = 66/258 (25%), Positives = 96/258 (37%), Gaps = 36/258 (13%)
Query: 796 PPVGSSYQPMQTNVVYNGPTCLPINAASSQEFDSVLFQQDATLSGLVNLGCQPLSSIPF- 854
PPV QP++ NGP LP+N + + L P ++ P
Sbjct: 692 PPVIPQAQPVRPP---NGPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMN 748
Query: 855 HSSNSGSTGHL--LAHTPHSVHTLPHLQSMGYHCSNT-GQRSLSSPVADQITGQPSSQLQ 911
HS S G + +A +P + P++ MG H +N Q S Q SS
Sbjct: 749 HSVQMNSMGSVPGMAISPSRMPQPPNM--MGAHTNNMMAQAPAQSQFLPQNQFPSSSGAM 806
Query: 912 PITYG--PSHSGSATTASPAASHPLASSPLS--GPPSPQLQPMPY-QSPSSGTASSPSPA 966
+ G P+ +G + P A+ P +PL+ GP + QL P QSP T S A
Sbjct: 807 SVGMGQPPAQTGVSQGQVPGAALP---NPLNMLGPQASQLPCPPVTQSPLHPTPPPASTA 863
Query: 967 TRMHSGQH-----------------STQAQSTGQGGLSAPSSLICHSLCDPASFPPDGAT 1009
M S QH ST S+GQ P S+ + A
Sbjct: 864 AGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQ 923
Query: 1010 VSIKPEPED--REPNFAT 1025
+ P+P+ + P+ AT
Sbjct: 924 AQVTPQPQTPVQPPSVAT 941
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.130 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 53,321,037
Number of Sequences: 37866
Number of extensions: 3225613
Number of successful extensions: 16997
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 102
Number of HSP's successfully gapped in prelim test: 737
Number of HSP's that attempted gapping in prelim test: 13454
Number of HSP's gapped (non-prelim): 3701
length of query: 1068
length of database: 18,247,518
effective HSP length: 113
effective length of query: 955
effective length of database: 13,968,660
effective search space: 13340070300
effective search space used: 13340070300
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.