Guide to the Human Genome
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Search of human proteins with 4758556

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4758556 PRP3 pre-mRNA processing factor 3 homolog [Homo
sapiens]
         (683 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4758556 PRP3 pre-mRNA processing factor 3 homolog [Homo sapiens]  1349   0.0  
gi|221139926 NHS-like 1 [Homo sapiens]                                 44   4e-04
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         43   0.001
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     42   0.002
gi|41322923 plectin 1 isoform 11 [Homo sapiens]                        41   0.004
gi|41322914 plectin 1 isoform 10 [Homo sapiens]                        41   0.004
gi|41322919 plectin 1 isoform 8 [Homo sapiens]                         41   0.004
gi|41322910 plectin 1 isoform 7 [Homo sapiens]                         41   0.004
gi|41322916 plectin 1 isoform 6 [Homo sapiens]                         41   0.004
gi|41322908 plectin 1 isoform 3 [Homo sapiens]                         41   0.004
gi|41322912 plectin 1 isoform 2 [Homo sapiens]                         41   0.004
gi|47607492 plectin 1 isoform 1 [Homo sapiens]                         41   0.004
gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [H...    40   0.005
gi|7661950 SH2 domain binding protein 1 [Homo sapiens]                 40   0.009
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]             39   0.016
gi|31652264 RNA binding motif protein 26 [Homo sapiens]                37   0.079
gi|78042577 MAP7 domain containing 1 [Homo sapiens]                    37   0.079
gi|46519147 ankyrin repeat and KH domain containing 1 isoform 1 ...    36   0.10 
gi|37620163 ANKHD1-EIF4EBP3 protein [Homo sapiens]                     36   0.10 
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi...    36   0.13 
gi|224591430 Ly1 antibody reactive homolog [Homo sapiens]              36   0.13 
gi|8923398 Ly1 antibody reactive homolog [Homo sapiens]                36   0.13 
gi|168229174 RNA binding motif protein 27 [Homo sapiens]               36   0.13 
gi|224589132 hypothetical protein LOC100132406 [Homo sapiens]          35   0.30 
gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens]             35   0.30 
gi|39930351 dynamin binding protein [Homo sapiens]                     35   0.30 
gi|71061468 centromere protein E [Homo sapiens]                        35   0.30 
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ...    35   0.30 
gi|112821690 G protein-regulated inducer of neurite outgrowth 3 ...    35   0.30 
gi|239741309 PREDICTED: hypothetical protein XP_002344485 [Homo ...    34   0.39 

>gi|4758556 PRP3 pre-mRNA processing factor 3 homolog [Homo sapiens]
          Length = 683

 Score = 1349 bits (3492), Expect = 0.0
 Identities = 683/683 (100%), Positives = 683/683 (100%)

Query: 1   MALSKRELDELKPWIEKTVKRVLGFSEPTVVTAALNCVGKGMDKKKAADHLKPFLDDSTL 60
           MALSKRELDELKPWIEKTVKRVLGFSEPTVVTAALNCVGKGMDKKKAADHLKPFLDDSTL
Sbjct: 1   MALSKRELDELKPWIEKTVKRVLGFSEPTVVTAALNCVGKGMDKKKAADHLKPFLDDSTL 60

Query: 61  RFVDKLFEAVEEGRSSRHSKSSSDRSRKRELKEVFGDDSEISKESSGVKKRRIPRFEEVE 120
           RFVDKLFEAVEEGRSSRHSKSSSDRSRKRELKEVFGDDSEISKESSGVKKRRIPRFEEVE
Sbjct: 61  RFVDKLFEAVEEGRSSRHSKSSSDRSRKRELKEVFGDDSEISKESSGVKKRRIPRFEEVE 120

Query: 121 EEPEVIPGPPSESPGMLTKLQIKQMMEAATRQIEERKKQLSFISPPTPQPKTPSSSQPER 180
           EEPEVIPGPPSESPGMLTKLQIKQMMEAATRQIEERKKQLSFISPPTPQPKTPSSSQPER
Sbjct: 121 EEPEVIPGPPSESPGMLTKLQIKQMMEAATRQIEERKKQLSFISPPTPQPKTPSSSQPER 180

Query: 181 LPIGNTIQPSQAATFMNDAIEKARKAAELQARIQAQLALKPGLIGNANMVGLANLHAMGI 240
           LPIGNTIQPSQAATFMNDAIEKARKAAELQARIQAQLALKPGLIGNANMVGLANLHAMGI
Sbjct: 181 LPIGNTIQPSQAATFMNDAIEKARKAAELQARIQAQLALKPGLIGNANMVGLANLHAMGI 240

Query: 241 APPKVELKDQTKPTPLILDEQGRTVDATGKEIELTHRMPTLKANIRAVKREQFKQQLKEK 300
           APPKVELKDQTKPTPLILDEQGRTVDATGKEIELTHRMPTLKANIRAVKREQFKQQLKEK
Sbjct: 241 APPKVELKDQTKPTPLILDEQGRTVDATGKEIELTHRMPTLKANIRAVKREQFKQQLKEK 300

Query: 301 PSEDMESNTFFDPRVSIAPSQRQRRTFKFHDKGKFEKIAQRLRTKAQLEKLQAEISQAAR 360
           PSEDMESNTFFDPRVSIAPSQRQRRTFKFHDKGKFEKIAQRLRTKAQLEKLQAEISQAAR
Sbjct: 301 PSEDMESNTFFDPRVSIAPSQRQRRTFKFHDKGKFEKIAQRLRTKAQLEKLQAEISQAAR 360

Query: 361 KTGIHTSTRLALIAPKKELKEGDIPEIEWWDSYIIPNGFDLTEENPKREDYFGITNLVEH 420
           KTGIHTSTRLALIAPKKELKEGDIPEIEWWDSYIIPNGFDLTEENPKREDYFGITNLVEH
Sbjct: 361 KTGIHTSTRLALIAPKKELKEGDIPEIEWWDSYIIPNGFDLTEENPKREDYFGITNLVEH 420

Query: 421 PAQLNPPVDNDTPVTLGVYLTKKEQKKLRRQTRREAQKELQEKVRLGLMPPPEPKVRISN 480
           PAQLNPPVDNDTPVTLGVYLTKKEQKKLRRQTRREAQKELQEKVRLGLMPPPEPKVRISN
Sbjct: 421 PAQLNPPVDNDTPVTLGVYLTKKEQKKLRRQTRREAQKELQEKVRLGLMPPPEPKVRISN 480

Query: 481 LMRVLGTEAVQDPTKVEAHVRAQMAKRQKAHEEANAARKLTAEQRKVKKIKKLKEDISQG 540
           LMRVLGTEAVQDPTKVEAHVRAQMAKRQKAHEEANAARKLTAEQRKVKKIKKLKEDISQG
Sbjct: 481 LMRVLGTEAVQDPTKVEAHVRAQMAKRQKAHEEANAARKLTAEQRKVKKIKKLKEDISQG 540

Query: 541 VHISVYRVRNLSNPAKKFKIEANAGQLYLTGVVVLHKDVNVVVVEGGPKAQKKFKRLMLH 600
           VHISVYRVRNLSNPAKKFKIEANAGQLYLTGVVVLHKDVNVVVVEGGPKAQKKFKRLMLH
Sbjct: 541 VHISVYRVRNLSNPAKKFKIEANAGQLYLTGVVVLHKDVNVVVVEGGPKAQKKFKRLMLH 600

Query: 601 RIKWDEQTSNTKGDDDEESDEEAVKKTNKCVLVWEGTAKDRSFGEMKFKQCPTENMAREH 660
           RIKWDEQTSNTKGDDDEESDEEAVKKTNKCVLVWEGTAKDRSFGEMKFKQCPTENMAREH
Sbjct: 601 RIKWDEQTSNTKGDDDEESDEEAVKKTNKCVLVWEGTAKDRSFGEMKFKQCPTENMAREH 660

Query: 661 FKKHGAEHYWDLALSESVLESTD 683
           FKKHGAEHYWDLALSESVLESTD
Sbjct: 661 FKKHGAEHYWDLALSESVLESTD 683


>gi|221139926 NHS-like 1 [Homo sapiens]
          Length = 1606

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 34/117 (29%), Positives = 52/117 (44%), Gaps = 3/117 (2%)

Query: 74   RSSRHSKSSSDRSRKRELKEVFGDDSEISKESSGVKKRRIPRFEEVEEEPEVIPGPPSES 133
            RS R S +SSD  +   LK+    D+     ++ + K   PRF+    EP   P  P ES
Sbjct: 1407 RSIRKSSTSSDNFKALLLKKGSRSDTSARMSAAEMLKNTDPRFQRSRSEPS--PDAP-ES 1463

Query: 134  PGMLTKLQIKQMMEAATRQIEERKKQLSFISPPTPQPKTPSSSQPERLPIGNTIQPS 190
            P   +  + ++  E   +      + LSF  P   + +TP S+   R  + N IQ S
Sbjct: 1464 PSSCSPSKNRRAQEEWAKNEGLMPRSLSFSGPRYGRSRTPPSAASSRYSMRNRIQSS 1520


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 46/187 (24%), Positives = 78/187 (41%), Gaps = 11/187 (5%)

Query: 3   LSKRELDELKPWIEKTVKRVLGFSEPTVVTAALNCVG-KGMDKKKAADHLKPFLDDSTLR 61
           +SK  L+ +KPWI K V  +LGF +  V+    N +  K  D K    +L  FL+    R
Sbjct: 40  MSKVNLEVIKPWITKRVTEILGFEDDVVIEFIFNQLEVKNPDSKMMQINLTGFLNGKNAR 99

Query: 62  -FVDKLFEAVEEGRSS-RHSKSSSDRSRKRELKEVFGDDSEIS---KESSGVKKRRIPRF 116
            F+ +L+  +   + +     S+    +K E+K+   +  +++   K+     KR     
Sbjct: 100 EFMGELWPLLLSAQENIAGIPSAFLELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEK 159

Query: 117 EEVEEEPEVIPGP-----PSESPGMLTKLQIKQMMEAATRQIEERKKQLSFISPPTPQPK 171
           E   E+ E    P      S SP   +    ++   + +R    R K  S    P  + K
Sbjct: 160 ESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEK 219

Query: 172 TPSSSQP 178
           TP   +P
Sbjct: 220 TPELPEP 226


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 104/520 (20%), Positives = 190/520 (36%), Gaps = 56/520 (10%)

Query: 71  EEGRSSRHSKSSSDRSRKRELKEVFGDDSE----ISKESSGVKKRRIPRFEEVEEEPEVI 126
           EEG     ++   + ++    +E    + E    + +E+    + + P  EE +   EV 
Sbjct: 486 EEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVK 545

Query: 127 PGPPSESPGMLTKLQIKQMMEAATRQIEERKKQLSFISPPTP------QPKTPSSSQ-PE 179
               ++SP    K + K   EA + + EE K      SP         + K+P+ ++ PE
Sbjct: 546 SPEKAKSPA---KEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPE 602

Query: 180 RLPIGNTIQPSQAATFMNDAIEKARKAAELQARIQAQLALKPGLIGNANMVGLANLHAMG 239
           +       +    A   +   E+A+  AE+++  +A+   K            A      
Sbjct: 603 KAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEE----------AKSPEKA 652

Query: 240 IAPPKVELKDQTKPTPLILDEQGRTVDATGKEIELTHRMPT-LKANIR--AVKREQFKQQ 296
            +P K E K   K    +  E  ++ +     ++   + P   K+ ++  A   E+ K  
Sbjct: 653 KSPEKEEAKSPEKAKSPVKAE-AKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSP 711

Query: 297 LKE--KPSEDMESNTFFDPRVSIAPSQRQRRTFKFHDKGKFEKIAQRLRTKAQLEKLQAE 354
           +KE  K  E  +S    + +         +   K  +K K  + A+ L  K+   K  A+
Sbjct: 712 VKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAK 771

Query: 355 ISQAARKTGIHTSTRLALIAPKKELKEGDIPEIEWWDSYIIPNGFDLTEENPKREDYFGI 414
             + AR        + A    K+E+K  +  +    +    P      +E PK+E+    
Sbjct: 772 --EEARSPADKFPEK-AKSPVKEEVKSPEKAKSPLKEDAKAPE-----KEIPKKEEVKSP 823

Query: 415 TNLVEHPAQLN---PPVDNDTPVTLGVYLT--KKEQKKLRRQTRREAQKELQEKVRLGLM 469
               E P ++    PP   +         T  KK+ KK     +   + +++EK    + 
Sbjct: 824 VKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVE 883

Query: 470 PPPEPKVRISNLMRVLGTEAVQDPTKV-----EAHVRAQMAKRQKAHEEANAARKLTAEQ 524
            P E KV           E  +D  KV     EA  + ++ +  K  E+   A+K   + 
Sbjct: 884 KPKESKVEAKK-------EEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKK-EPDD 935

Query: 525 RKVKKIKKLKEDISQGVHISVYRVRNLSNPAKKFKIEANA 564
            K K+  K  E           +      P +K K EA A
Sbjct: 936 AKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKA 975



 Score = 30.4 bits (67), Expect = 5.7
 Identities = 59/254 (23%), Positives = 98/254 (38%), Gaps = 36/254 (14%)

Query: 69  AVEEGRSSRHSKSSSDRSR-KRELKEVFGDDSEISKESSGVKKRRIPRFEEVEEEPEVIP 127
           A EE RS         +S  K E+K      S + KE +   ++ IP+ EEV+      P
Sbjct: 770 AKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPL-KEDAKAPEKEIPKKEEVKS-----P 823

Query: 128 GPPSESPGMLTKLQIKQMMEAATRQIEERKKQLSFISPPTPQPKTPSSSQPERLPIGNTI 187
               E P    ++++K+  + A    EE K      +P TP+ +    S+ E  P     
Sbjct: 824 VKEEEKP---QEVKVKEPPKKA----EEEK------APATPKTEEKKDSKKEEAPKKEAP 870

Query: 188 QPSQAATFMNDAIEKARKAAELQARIQAQLALKPGLIGNANMVGLANLHAMGIAPPKVEL 247
           +P +       A+EK +++     + +A+   K                    AP KVE+
Sbjct: 871 KP-KVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKE-------------APAKVEV 916

Query: 248 KDQTKPTPLILDEQGRTVDATGKEIELTHRMPTLKANIRAVKREQFKQQLKEKPSEDMES 307
           K+  KP       +    DA  KE              +  K E+ K+  +EKP  + ++
Sbjct: 917 KEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKP-EEKPKTEAKA 975

Query: 308 NTFFDPRVSIAPSQ 321
               D  +S  PS+
Sbjct: 976 KE-DDKTLSKEPSK 988


>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
          Length = 4547

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 101/518 (19%), Positives = 206/518 (39%), Gaps = 68/518 (13%)

Query: 68   EAVEEGRSSRHSKSSSD---------RSRKRELKEVFGDDSEISKESSGVKKRRIPRFEE 118
            E  + GR  R+ + S+D         R R+ +++ +   DS+  +E    ++  +   EE
Sbjct: 1201 ELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADSQAVREQLRQEQALL---EE 1257

Query: 119  VEEEPEVIPGPPSESPGMLTKLQIKQMMEAATRQIEERKKQLSFISPPTPQPKTPSSSQP 178
            +E   E +     E      K  I  + +    Q+   K QL  ++ P  +PK  S S+ 
Sbjct: 1258 IERHGEKV-----EECQRFAKQYINAIKDYEL-QLVTYKAQLEPVASPAKKPKVQSGSES 1311

Query: 179  ---ERLPIGN-----TIQPSQAATFMNDAI----EKARKAAELQARIQAQLALKPGLIGN 226
               E + +       T   SQ   F+++ +    E+ R A + +A  + +LA     +  
Sbjct: 1312 VIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEK 1371

Query: 227  ANMVGLANLHAMGIAPPKVELKD-QTKPTPLILDEQGRTVDATGKEIELTHRMPTLKANI 285
                 LA  HA   A  + E K+ Q +    ++  +   VDA  ++  +   +  L+ + 
Sbjct: 1372 QRQ--LAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSS 1429

Query: 286  RAVKREQFKQQLKEKPSEDMESNTFFDPRVSIAPSQRQRRTFKFH-------------DK 332
             A  + + +Q    + S           R+ +  ++RQR   +                K
Sbjct: 1430 EAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQK 1489

Query: 333  GKFEKIAQRLRTKAQLE---KLQAEISQAARKTGIHTSTR--------LALIAPKKELKE 381
             + ++ A+RLR + Q E   K QAE+  A+R      + R        L  +  + E  E
Sbjct: 1490 RQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAE 1549

Query: 382  GDIPEIEWWDSYIIPNGFDLTEENPKREDYFGITNLVEHPAQLNPPVDNDTPVTLGVYLT 441
              + + E   +  +    +  + + + E      +  E  AQL   +  +      +   
Sbjct: 1550 RRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQL--- 1606

Query: 442  KKEQKKLRRQTRREAQKELQEKVRLGLMPPPEPKVRISNLMRVLGTEAVQDPTKVEAHVR 501
             +E+ + R Q + EA++  +E  R   +   + K   +  +R+   E  Q  +  +A   
Sbjct: 1607 -REEAERRAQQQAEAERAREEAERE--LERWQLKANEALRLRLQAEEVAQQKSLAQAE-- 1661

Query: 502  AQMAKRQKAHEEANAARKLTAEQRKVKKIKKLKEDISQ 539
               A++QK   E  A R+  AE++ V++ +  ++++ +
Sbjct: 1662 ---AEKQKEEAEREARRRGKAEEQAVRQRELAEQELEK 1696



 Score = 30.8 bits (68), Expect = 4.3
 Identities = 65/382 (17%), Positives = 147/382 (38%), Gaps = 40/382 (10%)

Query: 202  KARKAAELQARIQAQLALKPGLIGNANMVGLANLHAMGIAPPKVELKDQTKPTPLILD-- 259
            + R+ AE ++  Q QLA +        +      HA  +   + EL+   +    +LD  
Sbjct: 2023 RLRERAEQESARQLQLAQEAA---QKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQL 2079

Query: 260  ----EQGRTVDATGKEIELTHRMPTLKANIRAVKREQFKQQLKEKPSEDMESNTFFDPRV 315
                E  R      +E  +       ++  +  + E+ KQ  +E+     ++    +   
Sbjct: 2080 RGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLR 2139

Query: 316  SIAPSQRQRRTFKFHDKGKFEKIAQRLRTKAQLEKLQAEISQAARKTGIHTSTRLALIAP 375
              A  +  RR      + +   + Q+    A++EK +    Q  R+          L   
Sbjct: 2140 KEAEQEAARRA-----QAEQAALRQKQAADAEMEKHKKFAEQTLRQKA---QVEQELTTL 2191

Query: 376  KKELKEGDIPEIEWWDSYIIPNGFDLTEENPKR----EDYFGITNLVEHPAQLNPPVDND 431
            + +L+E D  +    D  +     + TE   +R    E+ F +   +E  ++L   ++ +
Sbjct: 2192 RLQLEETDHQK-NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAE 2250

Query: 432  TPVTLGVYLTKKEQKKLRRQTRREAQKEL-QEKVRLGLMPPPEPKVR------------I 478
                +   L  K+  +   Q   E  K++ +E  RL +      ++R            +
Sbjct: 2251 NRALI---LRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRAL 2307

Query: 479  SNLMRVLGTEAVQDPTKVEAHVRAQMAKRQKAHEEANAARKLTAEQRKVKKIKKLKEDIS 538
            +  M     +AVQ+ T+++A   A++ ++QK   +  A R    +++  +++ +  +   
Sbjct: 2308 AEKMLKEKMQAVQEATRLKA--EAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQ 2365

Query: 539  QGVHISVYRVRNLSNPAKKFKI 560
            + +     R   +S  A++ K+
Sbjct: 2366 RTLEAERQRQLEMSAEAERLKL 2387


>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
          Length = 4551

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 101/518 (19%), Positives = 206/518 (39%), Gaps = 68/518 (13%)

Query: 68   EAVEEGRSSRHSKSSSD---------RSRKRELKEVFGDDSEISKESSGVKKRRIPRFEE 118
            E  + GR  R+ + S+D         R R+ +++ +   DS+  +E    ++  +   EE
Sbjct: 1205 ELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADSQAVREQLRQEQALL---EE 1261

Query: 119  VEEEPEVIPGPPSESPGMLTKLQIKQMMEAATRQIEERKKQLSFISPPTPQPKTPSSSQP 178
            +E   E +     E      K  I  + +    Q+   K QL  ++ P  +PK  S S+ 
Sbjct: 1262 IERHGEKV-----EECQRFAKQYINAIKDYEL-QLVTYKAQLEPVASPAKKPKVQSGSES 1315

Query: 179  ---ERLPIGN-----TIQPSQAATFMNDAI----EKARKAAELQARIQAQLALKPGLIGN 226
               E + +       T   SQ   F+++ +    E+ R A + +A  + +LA     +  
Sbjct: 1316 VIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEK 1375

Query: 227  ANMVGLANLHAMGIAPPKVELKD-QTKPTPLILDEQGRTVDATGKEIELTHRMPTLKANI 285
                 LA  HA   A  + E K+ Q +    ++  +   VDA  ++  +   +  L+ + 
Sbjct: 1376 QRQ--LAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSS 1433

Query: 286  RAVKREQFKQQLKEKPSEDMESNTFFDPRVSIAPSQRQRRTFKFH-------------DK 332
             A  + + +Q    + S           R+ +  ++RQR   +                K
Sbjct: 1434 EAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQK 1493

Query: 333  GKFEKIAQRLRTKAQLE---KLQAEISQAARKTGIHTSTR--------LALIAPKKELKE 381
             + ++ A+RLR + Q E   K QAE+  A+R      + R        L  +  + E  E
Sbjct: 1494 RQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAE 1553

Query: 382  GDIPEIEWWDSYIIPNGFDLTEENPKREDYFGITNLVEHPAQLNPPVDNDTPVTLGVYLT 441
              + + E   +  +    +  + + + E      +  E  AQL   +  +      +   
Sbjct: 1554 RRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQL--- 1610

Query: 442  KKEQKKLRRQTRREAQKELQEKVRLGLMPPPEPKVRISNLMRVLGTEAVQDPTKVEAHVR 501
             +E+ + R Q + EA++  +E  R   +   + K   +  +R+   E  Q  +  +A   
Sbjct: 1611 -REEAERRAQQQAEAERAREEAERE--LERWQLKANEALRLRLQAEEVAQQKSLAQAE-- 1665

Query: 502  AQMAKRQKAHEEANAARKLTAEQRKVKKIKKLKEDISQ 539
               A++QK   E  A R+  AE++ V++ +  ++++ +
Sbjct: 1666 ---AEKQKEEAEREARRRGKAEEQAVRQRELAEQELEK 1700



 Score = 30.8 bits (68), Expect = 4.3
 Identities = 65/382 (17%), Positives = 147/382 (38%), Gaps = 40/382 (10%)

Query: 202  KARKAAELQARIQAQLALKPGLIGNANMVGLANLHAMGIAPPKVELKDQTKPTPLILD-- 259
            + R+ AE ++  Q QLA +        +      HA  +   + EL+   +    +LD  
Sbjct: 2027 RLRERAEQESARQLQLAQEAA---QKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQL 2083

Query: 260  ----EQGRTVDATGKEIELTHRMPTLKANIRAVKREQFKQQLKEKPSEDMESNTFFDPRV 315
                E  R      +E  +       ++  +  + E+ KQ  +E+     ++    +   
Sbjct: 2084 RGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLR 2143

Query: 316  SIAPSQRQRRTFKFHDKGKFEKIAQRLRTKAQLEKLQAEISQAARKTGIHTSTRLALIAP 375
              A  +  RR      + +   + Q+    A++EK +    Q  R+          L   
Sbjct: 2144 KEAEQEAARRA-----QAEQAALRQKQAADAEMEKHKKFAEQTLRQKA---QVEQELTTL 2195

Query: 376  KKELKEGDIPEIEWWDSYIIPNGFDLTEENPKR----EDYFGITNLVEHPAQLNPPVDND 431
            + +L+E D  +    D  +     + TE   +R    E+ F +   +E  ++L   ++ +
Sbjct: 2196 RLQLEETDHQK-NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAE 2254

Query: 432  TPVTLGVYLTKKEQKKLRRQTRREAQKEL-QEKVRLGLMPPPEPKVR------------I 478
                +   L  K+  +   Q   E  K++ +E  RL +      ++R            +
Sbjct: 2255 NRALI---LRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRAL 2311

Query: 479  SNLMRVLGTEAVQDPTKVEAHVRAQMAKRQKAHEEANAARKLTAEQRKVKKIKKLKEDIS 538
            +  M     +AVQ+ T+++A   A++ ++QK   +  A R    +++  +++ +  +   
Sbjct: 2312 AEKMLKEKMQAVQEATRLKA--EAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQ 2369

Query: 539  QGVHISVYRVRNLSNPAKKFKI 560
            + +     R   +S  A++ K+
Sbjct: 2370 RTLEAERQRQLEMSAEAERLKL 2391


>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
          Length = 4547

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 101/518 (19%), Positives = 206/518 (39%), Gaps = 68/518 (13%)

Query: 68   EAVEEGRSSRHSKSSSD---------RSRKRELKEVFGDDSEISKESSGVKKRRIPRFEE 118
            E  + GR  R+ + S+D         R R+ +++ +   DS+  +E    ++  +   EE
Sbjct: 1201 ELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADSQAVREQLRQEQALL---EE 1257

Query: 119  VEEEPEVIPGPPSESPGMLTKLQIKQMMEAATRQIEERKKQLSFISPPTPQPKTPSSSQP 178
            +E   E +     E      K  I  + +    Q+   K QL  ++ P  +PK  S S+ 
Sbjct: 1258 IERHGEKV-----EECQRFAKQYINAIKDYEL-QLVTYKAQLEPVASPAKKPKVQSGSES 1311

Query: 179  ---ERLPIGN-----TIQPSQAATFMNDAI----EKARKAAELQARIQAQLALKPGLIGN 226
               E + +       T   SQ   F+++ +    E+ R A + +A  + +LA     +  
Sbjct: 1312 VIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEK 1371

Query: 227  ANMVGLANLHAMGIAPPKVELKD-QTKPTPLILDEQGRTVDATGKEIELTHRMPTLKANI 285
                 LA  HA   A  + E K+ Q +    ++  +   VDA  ++  +   +  L+ + 
Sbjct: 1372 QRQ--LAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSS 1429

Query: 286  RAVKREQFKQQLKEKPSEDMESNTFFDPRVSIAPSQRQRRTFKFH-------------DK 332
             A  + + +Q    + S           R+ +  ++RQR   +                K
Sbjct: 1430 EAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQK 1489

Query: 333  GKFEKIAQRLRTKAQLE---KLQAEISQAARKTGIHTSTR--------LALIAPKKELKE 381
             + ++ A+RLR + Q E   K QAE+  A+R      + R        L  +  + E  E
Sbjct: 1490 RQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAE 1549

Query: 382  GDIPEIEWWDSYIIPNGFDLTEENPKREDYFGITNLVEHPAQLNPPVDNDTPVTLGVYLT 441
              + + E   +  +    +  + + + E      +  E  AQL   +  +      +   
Sbjct: 1550 RRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQL--- 1606

Query: 442  KKEQKKLRRQTRREAQKELQEKVRLGLMPPPEPKVRISNLMRVLGTEAVQDPTKVEAHVR 501
             +E+ + R Q + EA++  +E  R   +   + K   +  +R+   E  Q  +  +A   
Sbjct: 1607 -REEAERRAQQQAEAERAREEAERE--LERWQLKANEALRLRLQAEEVAQQKSLAQAE-- 1661

Query: 502  AQMAKRQKAHEEANAARKLTAEQRKVKKIKKLKEDISQ 539
               A++QK   E  A R+  AE++ V++ +  ++++ +
Sbjct: 1662 ---AEKQKEEAEREARRRGKAEEQAVRQRELAEQELEK 1696



 Score = 30.8 bits (68), Expect = 4.3
 Identities = 65/382 (17%), Positives = 147/382 (38%), Gaps = 40/382 (10%)

Query: 202  KARKAAELQARIQAQLALKPGLIGNANMVGLANLHAMGIAPPKVELKDQTKPTPLILD-- 259
            + R+ AE ++  Q QLA +        +      HA  +   + EL+   +    +LD  
Sbjct: 2023 RLRERAEQESARQLQLAQEAA---QKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQL 2079

Query: 260  ----EQGRTVDATGKEIELTHRMPTLKANIRAVKREQFKQQLKEKPSEDMESNTFFDPRV 315
                E  R      +E  +       ++  +  + E+ KQ  +E+     ++    +   
Sbjct: 2080 RGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLR 2139

Query: 316  SIAPSQRQRRTFKFHDKGKFEKIAQRLRTKAQLEKLQAEISQAARKTGIHTSTRLALIAP 375
              A  +  RR      + +   + Q+    A++EK +    Q  R+          L   
Sbjct: 2140 KEAEQEAARRA-----QAEQAALRQKQAADAEMEKHKKFAEQTLRQKA---QVEQELTTL 2191

Query: 376  KKELKEGDIPEIEWWDSYIIPNGFDLTEENPKR----EDYFGITNLVEHPAQLNPPVDND 431
            + +L+E D  +    D  +     + TE   +R    E+ F +   +E  ++L   ++ +
Sbjct: 2192 RLQLEETDHQK-NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAE 2250

Query: 432  TPVTLGVYLTKKEQKKLRRQTRREAQKEL-QEKVRLGLMPPPEPKVR------------I 478
                +   L  K+  +   Q   E  K++ +E  RL +      ++R            +
Sbjct: 2251 NRALI---LRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRAL 2307

Query: 479  SNLMRVLGTEAVQDPTKVEAHVRAQMAKRQKAHEEANAARKLTAEQRKVKKIKKLKEDIS 538
            +  M     +AVQ+ T+++A   A++ ++QK   +  A R    +++  +++ +  +   
Sbjct: 2308 AEKMLKEKMQAVQEATRLKA--EAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQ 2365

Query: 539  QGVHISVYRVRNLSNPAKKFKI 560
            + +     R   +S  A++ K+
Sbjct: 2366 RTLEAERQRQLEMSAEAERLKL 2387


>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
          Length = 4515

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 101/518 (19%), Positives = 206/518 (39%), Gaps = 68/518 (13%)

Query: 68   EAVEEGRSSRHSKSSSD---------RSRKRELKEVFGDDSEISKESSGVKKRRIPRFEE 118
            E  + GR  R+ + S+D         R R+ +++ +   DS+  +E    ++  +   EE
Sbjct: 1169 ELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADSQAVREQLRQEQALL---EE 1225

Query: 119  VEEEPEVIPGPPSESPGMLTKLQIKQMMEAATRQIEERKKQLSFISPPTPQPKTPSSSQP 178
            +E   E +     E      K  I  + +    Q+   K QL  ++ P  +PK  S S+ 
Sbjct: 1226 IERHGEKV-----EECQRFAKQYINAIKDYEL-QLVTYKAQLEPVASPAKKPKVQSGSES 1279

Query: 179  ---ERLPIGN-----TIQPSQAATFMNDAI----EKARKAAELQARIQAQLALKPGLIGN 226
               E + +       T   SQ   F+++ +    E+ R A + +A  + +LA     +  
Sbjct: 1280 VIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEK 1339

Query: 227  ANMVGLANLHAMGIAPPKVELKD-QTKPTPLILDEQGRTVDATGKEIELTHRMPTLKANI 285
                 LA  HA   A  + E K+ Q +    ++  +   VDA  ++  +   +  L+ + 
Sbjct: 1340 QRQ--LAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSS 1397

Query: 286  RAVKREQFKQQLKEKPSEDMESNTFFDPRVSIAPSQRQRRTFKFH-------------DK 332
             A  + + +Q    + S           R+ +  ++RQR   +                K
Sbjct: 1398 EAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQK 1457

Query: 333  GKFEKIAQRLRTKAQLE---KLQAEISQAARKTGIHTSTR--------LALIAPKKELKE 381
             + ++ A+RLR + Q E   K QAE+  A+R      + R        L  +  + E  E
Sbjct: 1458 RQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAE 1517

Query: 382  GDIPEIEWWDSYIIPNGFDLTEENPKREDYFGITNLVEHPAQLNPPVDNDTPVTLGVYLT 441
              + + E   +  +    +  + + + E      +  E  AQL   +  +      +   
Sbjct: 1518 RRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQL--- 1574

Query: 442  KKEQKKLRRQTRREAQKELQEKVRLGLMPPPEPKVRISNLMRVLGTEAVQDPTKVEAHVR 501
             +E+ + R Q + EA++  +E  R   +   + K   +  +R+   E  Q  +  +A   
Sbjct: 1575 -REEAERRAQQQAEAERAREEAERE--LERWQLKANEALRLRLQAEEVAQQKSLAQAE-- 1629

Query: 502  AQMAKRQKAHEEANAARKLTAEQRKVKKIKKLKEDISQ 539
               A++QK   E  A R+  AE++ V++ +  ++++ +
Sbjct: 1630 ---AEKQKEEAEREARRRGKAEEQAVRQRELAEQELEK 1664



 Score = 30.8 bits (68), Expect = 4.3
 Identities = 65/382 (17%), Positives = 147/382 (38%), Gaps = 40/382 (10%)

Query: 202  KARKAAELQARIQAQLALKPGLIGNANMVGLANLHAMGIAPPKVELKDQTKPTPLILD-- 259
            + R+ AE ++  Q QLA +        +      HA  +   + EL+   +    +LD  
Sbjct: 1991 RLRERAEQESARQLQLAQEAA---QKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQL 2047

Query: 260  ----EQGRTVDATGKEIELTHRMPTLKANIRAVKREQFKQQLKEKPSEDMESNTFFDPRV 315
                E  R      +E  +       ++  +  + E+ KQ  +E+     ++    +   
Sbjct: 2048 RGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLR 2107

Query: 316  SIAPSQRQRRTFKFHDKGKFEKIAQRLRTKAQLEKLQAEISQAARKTGIHTSTRLALIAP 375
              A  +  RR      + +   + Q+    A++EK +    Q  R+          L   
Sbjct: 2108 KEAEQEAARRA-----QAEQAALRQKQAADAEMEKHKKFAEQTLRQKA---QVEQELTTL 2159

Query: 376  KKELKEGDIPEIEWWDSYIIPNGFDLTEENPKR----EDYFGITNLVEHPAQLNPPVDND 431
            + +L+E D  +    D  +     + TE   +R    E+ F +   +E  ++L   ++ +
Sbjct: 2160 RLQLEETDHQK-NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAE 2218

Query: 432  TPVTLGVYLTKKEQKKLRRQTRREAQKEL-QEKVRLGLMPPPEPKVR------------I 478
                +   L  K+  +   Q   E  K++ +E  RL +      ++R            +
Sbjct: 2219 NRALI---LRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRAL 2275

Query: 479  SNLMRVLGTEAVQDPTKVEAHVRAQMAKRQKAHEEANAARKLTAEQRKVKKIKKLKEDIS 538
            +  M     +AVQ+ T+++A   A++ ++QK   +  A R    +++  +++ +  +   
Sbjct: 2276 AEKMLKEKMQAVQEATRLKA--EAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQ 2333

Query: 539  QGVHISVYRVRNLSNPAKKFKI 560
            + +     R   +S  A++ K+
Sbjct: 2334 RTLEAERQRQLEMSAEAERLKL 2355


>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
          Length = 4684

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 101/518 (19%), Positives = 206/518 (39%), Gaps = 68/518 (13%)

Query: 68   EAVEEGRSSRHSKSSSD---------RSRKRELKEVFGDDSEISKESSGVKKRRIPRFEE 118
            E  + GR  R+ + S+D         R R+ +++ +   DS+  +E    ++  +   EE
Sbjct: 1338 ELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADSQAVREQLRQEQALL---EE 1394

Query: 119  VEEEPEVIPGPPSESPGMLTKLQIKQMMEAATRQIEERKKQLSFISPPTPQPKTPSSSQP 178
            +E   E +     E      K  I  + +    Q+   K QL  ++ P  +PK  S S+ 
Sbjct: 1395 IERHGEKV-----EECQRFAKQYINAIKDYEL-QLVTYKAQLEPVASPAKKPKVQSGSES 1448

Query: 179  ---ERLPIGN-----TIQPSQAATFMNDAI----EKARKAAELQARIQAQLALKPGLIGN 226
               E + +       T   SQ   F+++ +    E+ R A + +A  + +LA     +  
Sbjct: 1449 VIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEK 1508

Query: 227  ANMVGLANLHAMGIAPPKVELKD-QTKPTPLILDEQGRTVDATGKEIELTHRMPTLKANI 285
                 LA  HA   A  + E K+ Q +    ++  +   VDA  ++  +   +  L+ + 
Sbjct: 1509 QRQ--LAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSS 1566

Query: 286  RAVKREQFKQQLKEKPSEDMESNTFFDPRVSIAPSQRQRRTFKFH-------------DK 332
             A  + + +Q    + S           R+ +  ++RQR   +                K
Sbjct: 1567 EAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQK 1626

Query: 333  GKFEKIAQRLRTKAQLE---KLQAEISQAARKTGIHTSTR--------LALIAPKKELKE 381
             + ++ A+RLR + Q E   K QAE+  A+R      + R        L  +  + E  E
Sbjct: 1627 RQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAE 1686

Query: 382  GDIPEIEWWDSYIIPNGFDLTEENPKREDYFGITNLVEHPAQLNPPVDNDTPVTLGVYLT 441
              + + E   +  +    +  + + + E      +  E  AQL   +  +      +   
Sbjct: 1687 RRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQL--- 1743

Query: 442  KKEQKKLRRQTRREAQKELQEKVRLGLMPPPEPKVRISNLMRVLGTEAVQDPTKVEAHVR 501
             +E+ + R Q + EA++  +E  R   +   + K   +  +R+   E  Q  +  +A   
Sbjct: 1744 -REEAERRAQQQAEAERAREEAERE--LERWQLKANEALRLRLQAEEVAQQKSLAQAE-- 1798

Query: 502  AQMAKRQKAHEEANAARKLTAEQRKVKKIKKLKEDISQ 539
               A++QK   E  A R+  AE++ V++ +  ++++ +
Sbjct: 1799 ---AEKQKEEAEREARRRGKAEEQAVRQRELAEQELEK 1833



 Score = 30.8 bits (68), Expect = 4.3
 Identities = 65/382 (17%), Positives = 147/382 (38%), Gaps = 40/382 (10%)

Query: 202  KARKAAELQARIQAQLALKPGLIGNANMVGLANLHAMGIAPPKVELKDQTKPTPLILD-- 259
            + R+ AE ++  Q QLA +        +      HA  +   + EL+   +    +LD  
Sbjct: 2160 RLRERAEQESARQLQLAQEAA---QKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQL 2216

Query: 260  ----EQGRTVDATGKEIELTHRMPTLKANIRAVKREQFKQQLKEKPSEDMESNTFFDPRV 315
                E  R      +E  +       ++  +  + E+ KQ  +E+     ++    +   
Sbjct: 2217 RGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLR 2276

Query: 316  SIAPSQRQRRTFKFHDKGKFEKIAQRLRTKAQLEKLQAEISQAARKTGIHTSTRLALIAP 375
              A  +  RR      + +   + Q+    A++EK +    Q  R+          L   
Sbjct: 2277 KEAEQEAARRA-----QAEQAALRQKQAADAEMEKHKKFAEQTLRQKA---QVEQELTTL 2328

Query: 376  KKELKEGDIPEIEWWDSYIIPNGFDLTEENPKR----EDYFGITNLVEHPAQLNPPVDND 431
            + +L+E D  +    D  +     + TE   +R    E+ F +   +E  ++L   ++ +
Sbjct: 2329 RLQLEETDHQK-NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAE 2387

Query: 432  TPVTLGVYLTKKEQKKLRRQTRREAQKEL-QEKVRLGLMPPPEPKVR------------I 478
                +   L  K+  +   Q   E  K++ +E  RL +      ++R            +
Sbjct: 2388 NRALI---LRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRAL 2444

Query: 479  SNLMRVLGTEAVQDPTKVEAHVRAQMAKRQKAHEEANAARKLTAEQRKVKKIKKLKEDIS 538
            +  M     +AVQ+ T+++A   A++ ++QK   +  A R    +++  +++ +  +   
Sbjct: 2445 AEKMLKEKMQAVQEATRLKA--EAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQ 2502

Query: 539  QGVHISVYRVRNLSNPAKKFKI 560
            + +     R   +S  A++ K+
Sbjct: 2503 RTLEAERQRQLEMSAEAERLKL 2524


>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
          Length = 4525

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 101/518 (19%), Positives = 206/518 (39%), Gaps = 68/518 (13%)

Query: 68   EAVEEGRSSRHSKSSSD---------RSRKRELKEVFGDDSEISKESSGVKKRRIPRFEE 118
            E  + GR  R+ + S+D         R R+ +++ +   DS+  +E    ++  +   EE
Sbjct: 1179 ELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADSQAVREQLRQEQALL---EE 1235

Query: 119  VEEEPEVIPGPPSESPGMLTKLQIKQMMEAATRQIEERKKQLSFISPPTPQPKTPSSSQP 178
            +E   E +     E      K  I  + +    Q+   K QL  ++ P  +PK  S S+ 
Sbjct: 1236 IERHGEKV-----EECQRFAKQYINAIKDYEL-QLVTYKAQLEPVASPAKKPKVQSGSES 1289

Query: 179  ---ERLPIGN-----TIQPSQAATFMNDAI----EKARKAAELQARIQAQLALKPGLIGN 226
               E + +       T   SQ   F+++ +    E+ R A + +A  + +LA     +  
Sbjct: 1290 VIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEK 1349

Query: 227  ANMVGLANLHAMGIAPPKVELKD-QTKPTPLILDEQGRTVDATGKEIELTHRMPTLKANI 285
                 LA  HA   A  + E K+ Q +    ++  +   VDA  ++  +   +  L+ + 
Sbjct: 1350 QRQ--LAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSS 1407

Query: 286  RAVKREQFKQQLKEKPSEDMESNTFFDPRVSIAPSQRQRRTFKFH-------------DK 332
             A  + + +Q    + S           R+ +  ++RQR   +                K
Sbjct: 1408 EAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQK 1467

Query: 333  GKFEKIAQRLRTKAQLE---KLQAEISQAARKTGIHTSTR--------LALIAPKKELKE 381
             + ++ A+RLR + Q E   K QAE+  A+R      + R        L  +  + E  E
Sbjct: 1468 RQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAE 1527

Query: 382  GDIPEIEWWDSYIIPNGFDLTEENPKREDYFGITNLVEHPAQLNPPVDNDTPVTLGVYLT 441
              + + E   +  +    +  + + + E      +  E  AQL   +  +      +   
Sbjct: 1528 RRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQL--- 1584

Query: 442  KKEQKKLRRQTRREAQKELQEKVRLGLMPPPEPKVRISNLMRVLGTEAVQDPTKVEAHVR 501
             +E+ + R Q + EA++  +E  R   +   + K   +  +R+   E  Q  +  +A   
Sbjct: 1585 -REEAERRAQQQAEAERAREEAERE--LERWQLKANEALRLRLQAEEVAQQKSLAQAE-- 1639

Query: 502  AQMAKRQKAHEEANAARKLTAEQRKVKKIKKLKEDISQ 539
               A++QK   E  A R+  AE++ V++ +  ++++ +
Sbjct: 1640 ---AEKQKEEAEREARRRGKAEEQAVRQRELAEQELEK 1674



 Score = 30.8 bits (68), Expect = 4.3
 Identities = 65/382 (17%), Positives = 147/382 (38%), Gaps = 40/382 (10%)

Query: 202  KARKAAELQARIQAQLALKPGLIGNANMVGLANLHAMGIAPPKVELKDQTKPTPLILD-- 259
            + R+ AE ++  Q QLA +        +      HA  +   + EL+   +    +LD  
Sbjct: 2001 RLRERAEQESARQLQLAQEAA---QKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQL 2057

Query: 260  ----EQGRTVDATGKEIELTHRMPTLKANIRAVKREQFKQQLKEKPSEDMESNTFFDPRV 315
                E  R      +E  +       ++  +  + E+ KQ  +E+     ++    +   
Sbjct: 2058 RGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLR 2117

Query: 316  SIAPSQRQRRTFKFHDKGKFEKIAQRLRTKAQLEKLQAEISQAARKTGIHTSTRLALIAP 375
              A  +  RR      + +   + Q+    A++EK +    Q  R+          L   
Sbjct: 2118 KEAEQEAARRA-----QAEQAALRQKQAADAEMEKHKKFAEQTLRQKA---QVEQELTTL 2169

Query: 376  KKELKEGDIPEIEWWDSYIIPNGFDLTEENPKR----EDYFGITNLVEHPAQLNPPVDND 431
            + +L+E D  +    D  +     + TE   +R    E+ F +   +E  ++L   ++ +
Sbjct: 2170 RLQLEETDHQK-NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAE 2228

Query: 432  TPVTLGVYLTKKEQKKLRRQTRREAQKEL-QEKVRLGLMPPPEPKVR------------I 478
                +   L  K+  +   Q   E  K++ +E  RL +      ++R            +
Sbjct: 2229 NRALI---LRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRAL 2285

Query: 479  SNLMRVLGTEAVQDPTKVEAHVRAQMAKRQKAHEEANAARKLTAEQRKVKKIKKLKEDIS 538
            +  M     +AVQ+ T+++A   A++ ++QK   +  A R    +++  +++ +  +   
Sbjct: 2286 AEKMLKEKMQAVQEATRLKA--EAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQ 2343

Query: 539  QGVHISVYRVRNLSNPAKKFKI 560
            + +     R   +S  A++ K+
Sbjct: 2344 RTLEAERQRQLEMSAEAERLKL 2365


>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
          Length = 4533

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 101/518 (19%), Positives = 206/518 (39%), Gaps = 68/518 (13%)

Query: 68   EAVEEGRSSRHSKSSSD---------RSRKRELKEVFGDDSEISKESSGVKKRRIPRFEE 118
            E  + GR  R+ + S+D         R R+ +++ +   DS+  +E    ++  +   EE
Sbjct: 1187 ELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADSQAVREQLRQEQALL---EE 1243

Query: 119  VEEEPEVIPGPPSESPGMLTKLQIKQMMEAATRQIEERKKQLSFISPPTPQPKTPSSSQP 178
            +E   E +     E      K  I  + +    Q+   K QL  ++ P  +PK  S S+ 
Sbjct: 1244 IERHGEKV-----EECQRFAKQYINAIKDYEL-QLVTYKAQLEPVASPAKKPKVQSGSES 1297

Query: 179  ---ERLPIGN-----TIQPSQAATFMNDAI----EKARKAAELQARIQAQLALKPGLIGN 226
               E + +       T   SQ   F+++ +    E+ R A + +A  + +LA     +  
Sbjct: 1298 VIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEK 1357

Query: 227  ANMVGLANLHAMGIAPPKVELKD-QTKPTPLILDEQGRTVDATGKEIELTHRMPTLKANI 285
                 LA  HA   A  + E K+ Q +    ++  +   VDA  ++  +   +  L+ + 
Sbjct: 1358 QRQ--LAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSS 1415

Query: 286  RAVKREQFKQQLKEKPSEDMESNTFFDPRVSIAPSQRQRRTFKFH-------------DK 332
             A  + + +Q    + S           R+ +  ++RQR   +                K
Sbjct: 1416 EAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQK 1475

Query: 333  GKFEKIAQRLRTKAQLE---KLQAEISQAARKTGIHTSTR--------LALIAPKKELKE 381
             + ++ A+RLR + Q E   K QAE+  A+R      + R        L  +  + E  E
Sbjct: 1476 RQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAE 1535

Query: 382  GDIPEIEWWDSYIIPNGFDLTEENPKREDYFGITNLVEHPAQLNPPVDNDTPVTLGVYLT 441
              + + E   +  +    +  + + + E      +  E  AQL   +  +      +   
Sbjct: 1536 RRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQL--- 1592

Query: 442  KKEQKKLRRQTRREAQKELQEKVRLGLMPPPEPKVRISNLMRVLGTEAVQDPTKVEAHVR 501
             +E+ + R Q + EA++  +E  R   +   + K   +  +R+   E  Q  +  +A   
Sbjct: 1593 -REEAERRAQQQAEAERAREEAERE--LERWQLKANEALRLRLQAEEVAQQKSLAQAE-- 1647

Query: 502  AQMAKRQKAHEEANAARKLTAEQRKVKKIKKLKEDISQ 539
               A++QK   E  A R+  AE++ V++ +  ++++ +
Sbjct: 1648 ---AEKQKEEAEREARRRGKAEEQAVRQRELAEQELEK 1682



 Score = 30.8 bits (68), Expect = 4.3
 Identities = 65/382 (17%), Positives = 147/382 (38%), Gaps = 40/382 (10%)

Query: 202  KARKAAELQARIQAQLALKPGLIGNANMVGLANLHAMGIAPPKVELKDQTKPTPLILD-- 259
            + R+ AE ++  Q QLA +        +      HA  +   + EL+   +    +LD  
Sbjct: 2009 RLRERAEQESARQLQLAQEAA---QKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQL 2065

Query: 260  ----EQGRTVDATGKEIELTHRMPTLKANIRAVKREQFKQQLKEKPSEDMESNTFFDPRV 315
                E  R      +E  +       ++  +  + E+ KQ  +E+     ++    +   
Sbjct: 2066 RGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLR 2125

Query: 316  SIAPSQRQRRTFKFHDKGKFEKIAQRLRTKAQLEKLQAEISQAARKTGIHTSTRLALIAP 375
              A  +  RR      + +   + Q+    A++EK +    Q  R+          L   
Sbjct: 2126 KEAEQEAARRA-----QAEQAALRQKQAADAEMEKHKKFAEQTLRQKA---QVEQELTTL 2177

Query: 376  KKELKEGDIPEIEWWDSYIIPNGFDLTEENPKR----EDYFGITNLVEHPAQLNPPVDND 431
            + +L+E D  +    D  +     + TE   +R    E+ F +   +E  ++L   ++ +
Sbjct: 2178 RLQLEETDHQK-NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAE 2236

Query: 432  TPVTLGVYLTKKEQKKLRRQTRREAQKEL-QEKVRLGLMPPPEPKVR------------I 478
                +   L  K+  +   Q   E  K++ +E  RL +      ++R            +
Sbjct: 2237 NRALI---LRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRAL 2293

Query: 479  SNLMRVLGTEAVQDPTKVEAHVRAQMAKRQKAHEEANAARKLTAEQRKVKKIKKLKEDIS 538
            +  M     +AVQ+ T+++A   A++ ++QK   +  A R    +++  +++ +  +   
Sbjct: 2294 AEKMLKEKMQAVQEATRLKA--EAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQ 2351

Query: 539  QGVHISVYRVRNLSNPAKKFKI 560
            + +     R   +S  A++ K+
Sbjct: 2352 RTLEAERQRQLEMSAEAERLKL 2373


>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
          Length = 4574

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 101/518 (19%), Positives = 206/518 (39%), Gaps = 68/518 (13%)

Query: 68   EAVEEGRSSRHSKSSSD---------RSRKRELKEVFGDDSEISKESSGVKKRRIPRFEE 118
            E  + GR  R+ + S+D         R R+ +++ +   DS+  +E    ++  +   EE
Sbjct: 1228 ELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADSQAVREQLRQEQALL---EE 1284

Query: 119  VEEEPEVIPGPPSESPGMLTKLQIKQMMEAATRQIEERKKQLSFISPPTPQPKTPSSSQP 178
            +E   E +     E      K  I  + +    Q+   K QL  ++ P  +PK  S S+ 
Sbjct: 1285 IERHGEKV-----EECQRFAKQYINAIKDYEL-QLVTYKAQLEPVASPAKKPKVQSGSES 1338

Query: 179  ---ERLPIGN-----TIQPSQAATFMNDAI----EKARKAAELQARIQAQLALKPGLIGN 226
               E + +       T   SQ   F+++ +    E+ R A + +A  + +LA     +  
Sbjct: 1339 VIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEK 1398

Query: 227  ANMVGLANLHAMGIAPPKVELKD-QTKPTPLILDEQGRTVDATGKEIELTHRMPTLKANI 285
                 LA  HA   A  + E K+ Q +    ++  +   VDA  ++  +   +  L+ + 
Sbjct: 1399 QRQ--LAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSS 1456

Query: 286  RAVKREQFKQQLKEKPSEDMESNTFFDPRVSIAPSQRQRRTFKFH-------------DK 332
             A  + + +Q    + S           R+ +  ++RQR   +                K
Sbjct: 1457 EAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQK 1516

Query: 333  GKFEKIAQRLRTKAQLE---KLQAEISQAARKTGIHTSTR--------LALIAPKKELKE 381
             + ++ A+RLR + Q E   K QAE+  A+R      + R        L  +  + E  E
Sbjct: 1517 RQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAE 1576

Query: 382  GDIPEIEWWDSYIIPNGFDLTEENPKREDYFGITNLVEHPAQLNPPVDNDTPVTLGVYLT 441
              + + E   +  +    +  + + + E      +  E  AQL   +  +      +   
Sbjct: 1577 RRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQL--- 1633

Query: 442  KKEQKKLRRQTRREAQKELQEKVRLGLMPPPEPKVRISNLMRVLGTEAVQDPTKVEAHVR 501
             +E+ + R Q + EA++  +E  R   +   + K   +  +R+   E  Q  +  +A   
Sbjct: 1634 -REEAERRAQQQAEAERAREEAERE--LERWQLKANEALRLRLQAEEVAQQKSLAQAE-- 1688

Query: 502  AQMAKRQKAHEEANAARKLTAEQRKVKKIKKLKEDISQ 539
               A++QK   E  A R+  AE++ V++ +  ++++ +
Sbjct: 1689 ---AEKQKEEAEREARRRGKAEEQAVRQRELAEQELEK 1723



 Score = 30.8 bits (68), Expect = 4.3
 Identities = 65/382 (17%), Positives = 147/382 (38%), Gaps = 40/382 (10%)

Query: 202  KARKAAELQARIQAQLALKPGLIGNANMVGLANLHAMGIAPPKVELKDQTKPTPLILD-- 259
            + R+ AE ++  Q QLA +        +      HA  +   + EL+   +    +LD  
Sbjct: 2050 RLRERAEQESARQLQLAQEAA---QKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQL 2106

Query: 260  ----EQGRTVDATGKEIELTHRMPTLKANIRAVKREQFKQQLKEKPSEDMESNTFFDPRV 315
                E  R      +E  +       ++  +  + E+ KQ  +E+     ++    +   
Sbjct: 2107 RGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLR 2166

Query: 316  SIAPSQRQRRTFKFHDKGKFEKIAQRLRTKAQLEKLQAEISQAARKTGIHTSTRLALIAP 375
              A  +  RR      + +   + Q+    A++EK +    Q  R+          L   
Sbjct: 2167 KEAEQEAARRA-----QAEQAALRQKQAADAEMEKHKKFAEQTLRQKA---QVEQELTTL 2218

Query: 376  KKELKEGDIPEIEWWDSYIIPNGFDLTEENPKR----EDYFGITNLVEHPAQLNPPVDND 431
            + +L+E D  +    D  +     + TE   +R    E+ F +   +E  ++L   ++ +
Sbjct: 2219 RLQLEETDHQK-NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAE 2277

Query: 432  TPVTLGVYLTKKEQKKLRRQTRREAQKEL-QEKVRLGLMPPPEPKVR------------I 478
                +   L  K+  +   Q   E  K++ +E  RL +      ++R            +
Sbjct: 2278 NRALI---LRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRAL 2334

Query: 479  SNLMRVLGTEAVQDPTKVEAHVRAQMAKRQKAHEEANAARKLTAEQRKVKKIKKLKEDIS 538
            +  M     +AVQ+ T+++A   A++ ++QK   +  A R    +++  +++ +  +   
Sbjct: 2335 AEKMLKEKMQAVQEATRLKA--EAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQ 2392

Query: 539  QGVHISVYRVRNLSNPAKKFKI 560
            + +     R   +S  A++ K+
Sbjct: 2393 RTLEAERQRQLEMSAEAERLKL 2414


>gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [Homo
           sapiens]
          Length = 1251

 Score = 40.4 bits (93), Expect = 0.005
 Identities = 61/270 (22%), Positives = 110/270 (40%), Gaps = 34/270 (12%)

Query: 114 PRFEEV-EEEPEVI------PGPPSESPGMLTKLQIKQMMEAAT---RQIEERKKQLSFI 163
           P+  EV  +EP V       P PP     M  KLQ ++     T    Q +E  K+    
Sbjct: 174 PKSSEVWRDEPAVATGAASDPAPPGRPQEMGPKLQARETPSLPTPIPLQPKEEPKE---- 229

Query: 164 SPPTPQPKTPSSSQPERLPIGNTIQPSQAATFMNDAIEKARKAAELQARIQAQLALKPGL 223
             P P+P+  S +Q   LP   T  P++   ++   +E A     L  +I  Q    PG+
Sbjct: 230 -APAPEPQPGSQAQTSSLP--PTRDPARLVAWVLHRLEMALPQPVLHGKIGEQEPDSPGI 286

Query: 224 IGNANMVGLANLHAMGIAPPKVELKDQTKP-----TPLILDEQG-RTVDATGKEIELTHR 277
                 V   ++   G   P + L++   P       +    QG   V A  +E +   +
Sbjct: 287 CD----VQTISILPGGQVEPDLVLEEVEPPWEDAHQDVSTSPQGTEVVPAYEEENKAVEK 342

Query: 278 MPTLKANIRAVKREQFKQQLKEKPSEDME-SNTFFD----PRVSIAPSQRQ-RRTFKFHD 331
           MP   + I   K ++ +++ +E+  E+ E +    D     +V +  S+    R     D
Sbjct: 343 MPRELSRIEEEKEDEEEEEEEEEEEEEEEVTEVLLDSCVVSQVGVGQSEEDGTRPQSTSD 402

Query: 332 KGKFEKIAQRLRTKAQLEKLQAEISQAARK 361
           +  +E++ +  + +A+ EK + E  + A +
Sbjct: 403 QKLWEEVGEEAKKEAE-EKAKEEAEEVAEE 431


>gi|7661950 SH2 domain binding protein 1 [Homo sapiens]
          Length = 1173

 Score = 39.7 bits (91), Expect = 0.009
 Identities = 39/183 (21%), Positives = 72/183 (39%), Gaps = 13/183 (7%)

Query: 5    KRELDELKPWIEKTVKRVLGFSEPTVVTAALNCVGKGMDKKKAADHLKPFLDDST----- 59
            K+ L++   ++EKT K +L F+  T  T      G G  + K       F++D T     
Sbjct: 872  KKLLEQRAQYVEKT-KNILMFTGETEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLP 930

Query: 60   --LRFVDKLFEAVEEGRSSRHSKSSSDRSRKRELKEVFGDDSEISKESSGVKKRRIPRFE 117
               +   +     E+            + R+R  K   G D + ++     KKRR P+ E
Sbjct: 931  ISKKKKRRKGSGSEQEGEDEEGGERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAE 990

Query: 118  EVEEEPEVIPGPPSESPGMLTKLQIKQMMEAATRQIEERKKQLSFISPPTPQPKTPSSSQ 177
            +     +  P P    P M  K++ K ++ ++    +E K +++    P        S +
Sbjct: 991  K-----KKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDE 1045

Query: 178  PER 180
             E+
Sbjct: 1046 DEQ 1048


>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
          Length = 2817

 Score = 38.9 bits (89), Expect = 0.016
 Identities = 102/488 (20%), Positives = 172/488 (35%), Gaps = 94/488 (19%)

Query: 64   DKLFEAVEEGRSSRH---SKSSSDRSRKRELKEVFGDDSEISKESSGVKKRRIPRFEEVE 120
            +KL E +E    +      K  S+ S  +E + VF       ++S+  +K   P   E E
Sbjct: 594  EKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVF-----TRQDSNRSEKEATPVVHETE 648

Query: 121  EEPEVIPGPPSESPGMLTKLQIK-----QMMEAATRQIEERKKQLSFISPPTPQPKTPSS 175
             E    P P   S G   + Q       Q  +   +Q + +++Q   + P T  P  PSS
Sbjct: 649  PESGSQPRPAVLS-GYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQGVLPQTV-PSQPSS 706

Query: 176  SQ---PERLPIGNTIQPS--------------QAATFMNDAIEKARKAAELQARIQAQLA 218
            S    P   P+   +QP                  ++M+  +   R A ++       + 
Sbjct: 707  STVPPPPHRPLYQPMQPHPQHLASMGFDPRWLMMQSYMDPRMMSGRPAMDIPPIHPGMIP 766

Query: 219  LKPGLIGNANMVGLANL-------------HAMGIAPPKV----------ELKDQTKPTP 255
             KP L+    M G  N              HA+ ++ P++          E +  T P  
Sbjct: 767  PKP-LMRRDQMEGSPNSSESFEHIARSARDHAISLSEPRMLWGSDPYPHAEPQQATTPKA 825

Query: 256  LILDEQGRTVDATGKEIELTHRMPTLKANIRAVKREQFKQQLKEKPSEDMESNTFFDPRV 315
                E  R+  A  +E ++T         + A  +  F ++  E   +   S +  D R 
Sbjct: 826  TEEPEDVRSEAALDQE-QITAAYSVEHNQLEAHPKADFIRESSEAQVQKFLSRSVEDVRP 884

Query: 316  SIAPSQRQRRTFKFHDKGKFEKIAQRLRTKAQLEKLQAEISQAARKTGI-HTSTRLALIA 374
                +  Q   F+  D        Q+  +  Q E++ A  SQ +RK  + H S       
Sbjct: 885  HHTDANNQSACFEAPD--------QKTLSAPQEERISAVESQPSRKRSVSHGSNHTQKPD 936

Query: 375  PKKELKEGDIPE-----------IEWWDSYIIPNGFDLTEENPKREDYF--------GIT 415
             ++      IP+           IE  +      GF  + E PK E  +        G  
Sbjct: 937  EQRSEPSAGIPKVTSRCIDSKEPIERPEEKPKKEGFIRSSEGPKPEKVYKSKSETRWGPR 996

Query: 416  NLVEHPAQLNP-PVDNDTPVTLGVYLTKKEQKKLRRQTRREAQKELQEKV--------RL 466
                   ++N  PV    P+   V    KE+++ R++   E  +++ EKV        + 
Sbjct: 997  PSSNRREEVNDRPVRRSGPIKKPVLRDMKEEREQRKEKEGEKAEKVTEKVVVKPEKTEKK 1056

Query: 467  GLMPPPEP 474
             L PPP P
Sbjct: 1057 DLPPPPPP 1064



 Score = 35.0 bits (79), Expect = 0.23
 Identities = 40/167 (23%), Positives = 64/167 (38%), Gaps = 27/167 (16%)

Query: 79   SKSSSDRSRKRELKEVFGDDSEISKESSGVKKRRIPRF---------EEVEEEPEVIPGP 129
            SK   +R  ++  KE F   SE  K     K +   R+         EEV + P    GP
Sbjct: 956  SKEPIERPEEKPKKEGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGP 1015

Query: 130  PSESPGMLTKLQIKQMMEAATRQIEE---------RKKQLSFISPPTPQPKTPSSSQPER 180
              +      K + +Q  E    + E+          K +   + PP P P+ P+  QP+ 
Sbjct: 1016 IKKPVLRDMKEEREQRKEKEGEKAEKVTEKVVVKPEKTEKKDLPPPPPPPQPPAPIQPQS 1075

Query: 181  LPIGNTIQP-------SQAATFMNDAIEKARKAAELQARIQAQLALK 220
            +P    IQP       ++ AT      +   K  E  + +Q + A+K
Sbjct: 1076 VP--PPIQPEAEKFPSTETATLAQKPSQDTEKPLEPVSTVQVEPAVK 1120


>gi|31652264 RNA binding motif protein 26 [Homo sapiens]
          Length = 980

 Score = 36.6 bits (83), Expect = 0.079
 Identities = 31/118 (26%), Positives = 47/118 (39%), Gaps = 13/118 (11%)

Query: 9   DELKPWIEKTVKRVLGFSEPTVVTAALNCVGKGMDKKK----AADHLKPFLDDSTLRFVD 64
           + LK W+ KT++ +       +    L  V K   +K+      D L  FL   T  FV+
Sbjct: 11  EALKSWLSKTLEPICDADPSALAKYVLALVKKDKSEKELKALCIDQLDVFLQKETQIFVE 70

Query: 65  KLFEAVEEGRSSRHSKSSSDRSRKRELKEVFGDDSEISKESSGVKKRRIPRFEEVEEE 122
           KLF+AV         +  S  S K E             +   +KK  I + EE E++
Sbjct: 71  KLFDAVNTKSYLPPPEQPSSGSLKVEF---------FPHQEKDIKKEEITKEEEREKK 119


>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
          Length = 841

 Score = 36.6 bits (83), Expect = 0.079
 Identities = 37/136 (27%), Positives = 58/136 (42%), Gaps = 19/136 (13%)

Query: 403 EENPKREDYFGITNLVEHPAQLNPPVDNDTPVTLGVYLTKKEQKKLRRQTRREA--QKEL 460
           +E P  E       L   PA   PPV    P  +     ++E  +L  + RR+A  Q+E 
Sbjct: 560 KEQPPAETPTDAAVLTSPPAPA-PPVTPSKP--MAGTTDREEATRLLAEKRRQAREQRER 616

Query: 461 QEKVRLGLMPPPEPKVRISNLMRVLGTEAVQDPTKVEAHVRAQMAKRQKAHEEANAARKL 520
           +E+ R  L    + ++R   L R             EA  RA+     +  EE  A  K 
Sbjct: 617 EEQERR-LQAERDKRMREEQLAR-------------EAEARAEREAEARRREEQEAREKA 662

Query: 521 TAEQRKVKKIKKLKED 536
            AEQ + ++++K KE+
Sbjct: 663 QAEQEEQERLQKQKEE 678



 Score = 32.0 bits (71), Expect = 1.9
 Identities = 28/100 (28%), Positives = 41/100 (41%), Gaps = 1/100 (1%)

Query: 430 NDTPVTLGVYLTKKEQKKLRRQTRREAQKELQEKVRLGLMPPPEPKVRISNLMRVLGTEA 489
           +D+P T        E+ KL ++ R E  K L  K  + L    + K      ++      
Sbjct: 123 SDSPPTKQEVKKAGERHKLAKERREERAKYLAAKKAVWLEKEEKAKALREKQLQERRRRL 182

Query: 490 VQDPTKVEAHVRAQMAKRQKAHEEANAARKLTAEQRKVKK 529
            +   K E   RA + +RQ+   E N  R   A QR VKK
Sbjct: 183 EEQRLKAEQR-RAALEERQRQKLEKNKERYEAAIQRSVKK 221


>gi|46519147 ankyrin repeat and KH domain containing 1 isoform 1 [Homo
            sapiens]
          Length = 2542

 Score = 36.2 bits (82), Expect = 0.10
 Identities = 33/135 (24%), Positives = 52/135 (38%), Gaps = 11/135 (8%)

Query: 69   AVEEGRSSRHSKSSSDRSRKRELKEVFGDDSEISKESSGVKKRRIPRFEEVEEEPEVIPG 128
            A  E R  +  K   ++ RK+E      D+    KE+S      +P  E+ EE  E +  
Sbjct: 1451 AKREKRKEKRKKKKEEQKRKQE-----EDEENKPKENS-----ELPEDEDEEENDEDVEQ 1500

Query: 129  P-PSESPGMLTKLQIKQMMEAATRQIEERKKQLSFISPPTPQPKTPSSSQPERLPIGNTI 187
              P E P   T   I     +AT      KK+ + ++ P+   K   +   E  P  + I
Sbjct: 1501 EVPIEPPSATTTTTIGISATSATFTNVFGKKRANVVTTPSTNRKNKKNKTKETPPTAHLI 1560

Query: 188  QPSQAATFMNDAIEK 202
             P Q  +      +K
Sbjct: 1561 LPEQHMSLAQQKADK 1575


>gi|37620163 ANKHD1-EIF4EBP3 protein [Homo sapiens]
          Length = 2617

 Score = 36.2 bits (82), Expect = 0.10
 Identities = 33/135 (24%), Positives = 52/135 (38%), Gaps = 11/135 (8%)

Query: 69   AVEEGRSSRHSKSSSDRSRKRELKEVFGDDSEISKESSGVKKRRIPRFEEVEEEPEVIPG 128
            A  E R  +  K   ++ RK+E      D+    KE+S      +P  E+ EE  E +  
Sbjct: 1451 AKREKRKEKRKKKKEEQKRKQE-----EDEENKPKENS-----ELPEDEDEEENDEDVEQ 1500

Query: 129  P-PSESPGMLTKLQIKQMMEAATRQIEERKKQLSFISPPTPQPKTPSSSQPERLPIGNTI 187
              P E P   T   I     +AT      KK+ + ++ P+   K   +   E  P  + I
Sbjct: 1501 EVPIEPPSATTTTTIGISATSATFTNVFGKKRANVVTTPSTNRKNKKNKTKETPPTAHLI 1560

Query: 188  QPSQAATFMNDAIEK 202
             P Q  +      +K
Sbjct: 1561 LPEQHMSLAQQKADK 1575


>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo
           sapiens]
          Length = 1341

 Score = 35.8 bits (81), Expect = 0.13
 Identities = 73/325 (22%), Positives = 117/325 (36%), Gaps = 45/325 (13%)

Query: 74  RSSRHSKSSSDRSRKRELKEVFGDDSEISKESSGVKKRRIPRFEEVEEEPEVIPGPPSE- 132
           R+ R+ K+  +   + E +E   DD E   +  G K R  P  +E +EE E IP    E 
Sbjct: 262 RADRNLKTEEEEEEEEEEEE---DDEEEEGDDEGQKSREAPILKEFKEEGEEIPRVKPEE 318

Query: 133 --SPGMLTKLQIKQMMEAA---TRQIEERKKQLSFISPPTPQPKTPSSSQPERLPIGNTI 187
                  T+ Q ++++E     TR  EE +K          + KT S  + E       I
Sbjct: 319 MMDERPKTRSQEQEVLERGGRFTRSQEEARKSHLARQQQEKEMKTTSPLEEEE----REI 374

Query: 188 QPSQAATFMNDAIEKARKAAELQARIQAQLALKPGLIGNANMVGLANLHAMGIAPPKVEL 247
           + SQ     + +    R   +   R +A L   P    +               PP +  
Sbjct: 375 KSSQGLKEKSKSPSPPRLTED---RKKASLVALPEQTASEEE-----------TPPPLLT 420

Query: 248 KDQTKPTP---LILDEQGRTVDATGKEIELTHRMPTLKANIRAVKREQFKQQL------K 298
           K+ + P P   L  +E+   ++     + +    P   A+ R +   Q   QL       
Sbjct: 421 KEASSPPPHPQLHSEEEIEPMEGPAPPVLIQLSPPNTDADTRELLVSQHTVQLVGGLSPL 480

Query: 299 EKPSE-DMESNTFFDPRVSIAPSQRQRRTFKFHDKGKFEKIAQRLRTKAQLEKLQAEISQ 357
             PS+   ES     P  S+ P  ++     +  +   E  + R       + L  +I +
Sbjct: 481 SSPSDTKAESPAEKVPEESVLPLVQKSTLADYSAQKDLEPESDR-----SAQPLPLKIEE 535

Query: 358 AARKTGIHTSTRLALIAPKKELKEG 382
            A   GI   T   L  P  E KEG
Sbjct: 536 LALAKGI---TEECLKQPSLEQKEG 557


>gi|224591430 Ly1 antibody reactive homolog [Homo sapiens]
          Length = 379

 Score = 35.8 bits (81), Expect = 0.13
 Identities = 36/151 (23%), Positives = 69/151 (45%), Gaps = 11/151 (7%)

Query: 38  VGKGMDKKKAADHLKPFLDDSTLRFVDKLFEAVEEG----RSSRHSKSSSDRSRKRELKE 93
           V K  D++       P  + ST     K+ +AVE+     ++ R  K    + RKRE KE
Sbjct: 146 VNKEQDQRPLHPVANPHAEISTKVPASKVKDAVEQQGEVKKNKRERKEERQKKRKREKKE 205

Query: 94  VFGDDSEISKESSGVKKRRIPRFEEVEEEPEVIPGPPSESPGMLTKLQIKQMMEAATRQ- 152
           +  ++ + +  +   KKR+  +  ++E   E +P   + S G  +K + KQ  ++A+ + 
Sbjct: 206 LKLENHQENSRNQKPKKRKKGQEADLEAGGEEVP-EANGSAGKRSKKK-KQRKDSASEEE 263

Query: 153 ----IEERKKQLSFISPPTPQPKTPSSSQPE 179
                 +RK++ S +   + + K      PE
Sbjct: 264 ARVGAGKRKRRHSEVETDSKKKKMKLPEHPE 294


>gi|8923398 Ly1 antibody reactive homolog [Homo sapiens]
          Length = 379

 Score = 35.8 bits (81), Expect = 0.13
 Identities = 36/151 (23%), Positives = 69/151 (45%), Gaps = 11/151 (7%)

Query: 38  VGKGMDKKKAADHLKPFLDDSTLRFVDKLFEAVEEG----RSSRHSKSSSDRSRKRELKE 93
           V K  D++       P  + ST     K+ +AVE+     ++ R  K    + RKRE KE
Sbjct: 146 VNKEQDQRPLHPVANPHAEISTKVPASKVKDAVEQQGEVKKNKRERKEERQKKRKREKKE 205

Query: 94  VFGDDSEISKESSGVKKRRIPRFEEVEEEPEVIPGPPSESPGMLTKLQIKQMMEAATRQ- 152
           +  ++ + +  +   KKR+  +  ++E   E +P   + S G  +K + KQ  ++A+ + 
Sbjct: 206 LKLENHQENSRNQKPKKRKKGQEADLEAGGEEVP-EANGSAGKRSKKK-KQRKDSASEEE 263

Query: 153 ----IEERKKQLSFISPPTPQPKTPSSSQPE 179
                 +RK++ S +   + + K      PE
Sbjct: 264 ARVGAGKRKRRHSEVETDSKKKKMKLPEHPE 294


>gi|168229174 RNA binding motif protein 27 [Homo sapiens]
          Length = 1060

 Score = 35.8 bits (81), Expect = 0.13
 Identities = 21/68 (30%), Positives = 33/68 (48%), Gaps = 4/68 (5%)

Query: 7  ELDELKPWIEKTVKRVLGFSEPTVVTAALNCVGKGMDKKK----AADHLKPFLDDSTLRF 62
          ++D LK W+ K ++ +       +    +  V K   +K+     AD L  FL   T  F
Sbjct: 5  DVDALKSWLAKLLEPICDADPSALANYVVALVKKDKPEKELKAFCADQLDVFLQKETSGF 64

Query: 63 VDKLFEAV 70
          VDKLFE++
Sbjct: 65 VDKLFESL 72


>gi|224589132 hypothetical protein LOC100132406 [Homo sapiens]
          Length = 3628

 Score = 34.7 bits (78), Expect = 0.30
 Identities = 52/227 (22%), Positives = 98/227 (43%), Gaps = 16/227 (7%)

Query: 249 DQTKPTPLILDEQGRTVDATGKEIELTHR-MPTLKANIRAVK-REQFKQQLKEKPSE--D 304
           D+ +    IL   G T  AT   + ++   + + KA +  ++  E+ + QL EK  +  +
Sbjct: 249 DECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRN 308

Query: 305 MESNTFFDPRVSIAPSQRQRRTFKFHDKGKFEKIAQRLRTKAQLEKLQAEISQAAR---- 360
           ++   F         +Q+++  +K+ +     K   R   + + EKL  ++ QA      
Sbjct: 309 LKEKCFLTQLSGFLANQQKK--YKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQY 366

Query: 361 KTGIHTSTRLALIAPKKELKEGDIPEI---EWWDSYIIPNGFDLTEENPKREDYFGITNL 417
           K  +H   R  L   K++L+EG        E   + + P   D ++    +E       L
Sbjct: 367 KVLVHAQER-ELTQLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQDLQEQLAEGCRL 425

Query: 418 VEHPAQ-LNPPVDNDTPVTLGVYLTKKEQK-KLRRQTRREAQKELQE 462
            +H  Q L+P  DND    + V + +K QK    R+ ++  +KE+ E
Sbjct: 426 AQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPE 472


>gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens]
          Length = 2440

 Score = 34.7 bits (78), Expect = 0.30
 Identities = 28/117 (23%), Positives = 46/117 (39%), Gaps = 12/117 (10%)

Query: 68  EAVEEGRSSRHSKSSSDRSRKRELKEVFGDDSEISKESSGVKKRRIPRFEEVEEEPEVIP 127
           E VEE    +  K+      K++ +E   D+ E SKE++  K +     EE EE  +  P
Sbjct: 512 EKVEEKEEDKAEKTEKKEEEKKDEEEK--DEKEDSKENTKEKDKIDGTAEETEEREQATP 569

Query: 128 ------GPPSESPGMLTKLQIKQMMEAATRQIEERKKQLSFISPPTPQPKTPSSSQP 178
                        G +T+    +   A+       ++      PP P P  P S++P
Sbjct: 570 RGRKTANSQGRRKGRITRSMTNEAAAASAAAAAATEEP----PPPLPPPPEPISTEP 622


>gi|39930351 dynamin binding protein [Homo sapiens]
          Length = 1577

 Score = 34.7 bits (78), Expect = 0.30
 Identities = 54/237 (22%), Positives = 102/237 (43%), Gaps = 38/237 (16%)

Query: 117 EEVEEEPEVIPGPPSESPGMLTKLQI------KQMMEAATRQIEERK--KQLSFISPPTP 168
           +++ E  + + GP +E   +L    I      K ++  +++ I E++  ++   + PP P
Sbjct: 554 QQLIEFEKSLAGPGTEPDKILRHFSIMDFNSEKDIVRGSSKLITEQELPERRKALRPPPP 613

Query: 169 QPKTPSSSQPERLPIGNTIQPSQAATFMNDAIEKARKAAELQARIQAQLALKPGLIGNAN 228
           +P TP S+ P  L +   ++P+         +  +R A    +  Q   A+ P L+ + +
Sbjct: 614 RPCTPVSTSPHLL-VDQNLKPAPPL-----VVRPSRPAPLPPSAQQRTNAVSPKLL-SRH 666

Query: 229 MVGLANLHAMGIAPPKVELKDQTKPTPLIL---DEQGRTVDATGK---EIEL-------- 274
                 L   G       L DQT P PL+L   +E  R +D   +   E+ L        
Sbjct: 667 RPTCETLEKEGPGHMGRSL-DQTSPCPLVLVRIEEMERDLDMYSRAQEELNLMLEEKQDE 725

Query: 275 THRMPTL------KANIRAVKREQFKQQLKEKPSEDMESNTFFDPRVSIAPSQRQRR 325
           + R  TL      ++NI ++  E   QQL+E      +S++   P  S++    ++R
Sbjct: 726 SSRAETLEDLKFCESNIESLNME--LQQLREMTLLSSQSSSLVAPSGSVSAENPEQR 780


>gi|71061468 centromere protein E [Homo sapiens]
          Length = 2701

 Score = 34.7 bits (78), Expect = 0.30
 Identities = 75/383 (19%), Positives = 141/383 (36%), Gaps = 54/383 (14%)

Query: 7    ELDELKPWIEKTVKRVLGFSEPTVVTAALNCVGKGMDKKKAADHLKPF----------LD 56
            E D+LK   ++ V ++    E       +  V +  +K    +HLK            ++
Sbjct: 1605 ERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIE 1664

Query: 57   DSTLRFVDKLFEAVEEGRSSRHSKSSSDRSRKRELKEVFGDDSEISKESSGVKKRRIPRF 116
               +R    L E +EE RS      + +R   R ++E    + +  KE+    +  I R 
Sbjct: 1665 TENIRLTQILHENLEEMRSV-----TKERDDLRSVEETLKVERDQLKENL---RETITRD 1716

Query: 117  EEVEEEPEVIPGPPSESPGMLTKLQIKQMMEAATRQIEERKKQLSFISPPTPQPKTPSSS 176
             E +EE +++     E    + KL  + ++   T +I   +K L   +      K     
Sbjct: 1717 LEKQEELKIVHMHLKEHQETIDKL--RGIVSEKTNEISNMQKDLEHSNDAL---KAQDLK 1771

Query: 177  QPERLPIGNTIQPSQAATF---------MNDAIEKARKA-----AELQARIQAQLALKPG 222
              E L I +     Q  T            D +   +K      A+LQ +IQ   A +  
Sbjct: 1772 IQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQ 1831

Query: 223  LIGNANMVGLANLHAMGIAPPKVELKDQTKPTPLILDEQGRTVDATGKEIELTHRMPTLK 282
            LI     V         +   K ++KDQ+     +  E         + +E    +   +
Sbjct: 1832 LITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKER 1891

Query: 283  ANIRAVK------REQFKQQLKEKPSEDMESNTFFDPRVSIAPSQRQRRTFKFHDKGKFE 336
             N+R V+      R+Q K+ L+E  + D+E          I    +  R      K   +
Sbjct: 1892 DNLRRVEETLKLERDQLKESLQETKARDLE----------IQQELKTARMLSKEHKETVD 1941

Query: 337  KIAQRLRTKA-QLEKLQAEISQA 358
            K+ +++  K  Q+  +Q ++ ++
Sbjct: 1942 KLREKISEKTIQISDIQKDLDKS 1964


>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
            transmembrane signal), 1 [Homo sapiens]
          Length = 3259

 Score = 34.7 bits (78), Expect = 0.30
 Identities = 100/532 (18%), Positives = 213/532 (40%), Gaps = 73/532 (13%)

Query: 64   DKLFEAVEEGRSSRHSKSSSDRSRKRELKEVFGDDSEISKESSGVKKRRIPRFEEVEEEP 123
            +KL + +E  +SS+ ++S+  + + +EL++ +    +  +  S   +R     E V +E 
Sbjct: 1584 EKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEK 1643

Query: 124  EVIPGPPSESPGMLTKLQIKQMMEAATRQIEERKKQLSFISPPTPQPKTPSSSQPERL-- 181
            + + G    +     K + ++ ++ A +++EE K+++   +    Q       + +RL  
Sbjct: 1644 QELYGKLRSTEA--NKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRA 1701

Query: 182  ---PIGNTIQPSQAATF-----MNDAIEKARKAAE-LQARIQAQLALKPGLIGNANMVGL 232
               P G+T +            M + +E+ +   E L  + Q+ ++ K  L         
Sbjct: 1702 EVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQ---- 1757

Query: 233  ANLHAMGIAPPKVELKDQTKPTPLILDEQGRTVDATGKEIELTHRMPTLKANIRAVKREQ 292
                         +LK Q +        +   ++AT K    T+       +I     EQ
Sbjct: 1758 -------------DLKHQIEGNV----SKQANLEATEKHDNQTNVTEEGTQSIPGETEEQ 1800

Query: 293  FKQQLKEKP--SEDMESNTFFDPRVSIAPSQRQRRTFKFHDK--GKFEKIAQRLRTKAQL 348
                +  +P  SE + S    +P VS        + F  HD+     ++I Q     A L
Sbjct: 1801 DSLSMSTRPTCSESVPSAKSANPAVS--------KDFSSHDEINNYLQQIDQLKERIAGL 1852

Query: 349  EKLQAEISQAARKTGIHTSTRLALIAPKK-ELK--EGDIPEIEWWDSYIIPNGFDLT--E 403
            E+ + +  + ++      +T L+ I+ K  ELK  + ++ ++   +  I      +T  +
Sbjct: 1853 EEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLK 1912

Query: 404  ENPKREDYFGITNLVEHPAQLNPPVDN----DTPVTLGVYLTKKEQKKLRR---QTRREA 456
            E  + E       L+   A+LN  + N     T   +   L + E K L++   +   E 
Sbjct: 1913 ETAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEK 1972

Query: 457  QKELQEKVRLGLMPPPEPKVRISNLMRVLGTEAVQDPTKVEAHVRAQMAKRQKAHEEANA 516
            Q+ ++EK ++      E ++R   L ++ G  A ++P         Q   ++K  E    
Sbjct: 1973 QQLVKEKTKV------ESEIRKEYLEKIQG--AQKEPGNKSHAKELQELLKEKQQEVKQL 2024

Query: 517  AR-------KLTAEQRKVKKIKKLKEDISQGVHISVYRVRNLSNPAKKFKIE 561
             +       K++A +R VK ++ ++ +  + + I+   +       KK + E
Sbjct: 2025 QKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAE 2076



 Score = 30.4 bits (67), Expect = 5.7
 Identities = 58/251 (23%), Positives = 93/251 (37%), Gaps = 35/251 (13%)

Query: 139 KLQIKQMMEAATRQIEERKKQLSFISPPTPQ-----PKTPSSSQPERLPI---------- 183
           KL  K  + +  + IEE K Q   + P  PQ      K   SS  E + I          
Sbjct: 97  KLHAKAKLTSLNKYIEEMKAQGGTVLPTEPQSEEQLSKHDKSSTEEEMEIEKIKHKLQEK 156

Query: 184 GNTIQPSQAATFMNDAIEKARKAAELQ--ARIQAQLALKPGLIGNANMVGLANLHAMGIA 241
              I   QA      A + A+ + E++    ++ QL  K   I       L+   A   A
Sbjct: 157 EELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEKEEFISTL-QAQLSQTQAEQAA 215

Query: 242 PPKVELKDQTKPTPLIL--DEQGRTVDATGKEIELTHRMPTLKANIR-----AVKREQFK 294
              V  KD    T + L  DE  + V     E E+  ++  L+  +       V R Q  
Sbjct: 216 QQVVREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVV 275

Query: 295 QQLKEKPSEDMESNTFFDPRVSIAPSQRQRRTFKFHDKGKFEKIAQRLRTKAQLEKLQAE 354
             L+++ +   + N           SQ+ ++    H+  +     +R  +K  LEK++ E
Sbjct: 276 DLLQQELTAAEQRNQIL--------SQQLQQMEAEHNTLRNTVETEREESKILLEKMELE 327

Query: 355 ISQAARKTGIH 365
           +  A RK   H
Sbjct: 328 V--AERKLSFH 336


>gi|112821690 G protein-regulated inducer of neurite outgrowth 3
           [Homo sapiens]
          Length = 776

 Score = 34.7 bits (78), Expect = 0.30
 Identities = 49/228 (21%), Positives = 84/228 (36%), Gaps = 33/228 (14%)

Query: 96  GDDSEISKESSGVKKRRIPRFEEVEEEPEVIPGPPSESPGML------TKLQIKQMMEAA 149
           GD  E    S  V K +     +  +   ++  P S+  G        T   I++  E+ 
Sbjct: 533 GDAREKKPASPQVVKEKESTGTDTSDAKTLLLNPKSQESGGTESAANPTPSPIRKNQEST 592

Query: 150 TRQIEERKKQLSFISPPTPQ-PKTPSSSQ--PERLPIGNTIQPSQAATFMNDAIEKARKA 206
             +  + K   S   P  P    +P S +  P R    +  +PS+ + F+ +       A
Sbjct: 593 LEENRQTKTATSLSLPSDPMGDSSPGSGKKTPSRSVKASPRRPSRVSEFLKEQKLNVTAA 652

Query: 207 AELQARIQAQLALKPGLIGNANMVGLANLHAMGIAPPKVELKDQTKPTPLILDEQGRTVD 266
           A       AQ+ L PG       +G         A  K++LK   +   ++ DEQG T +
Sbjct: 653 A-------AQVGLTPG--DKKKQLG---------ADSKLQLKQSKRVRDVVWDEQGMTWE 694

Query: 267 ATGKEIELTHRMPTLKANIRAVKREQFK------QQLKEKPSEDMESN 308
             G  ++       ++ +++   RE  K       Q +   S D  SN
Sbjct: 695 VYGASLDAESLGIAIQNHLQRQIREHEKLIKTQNSQTRRSISSDTSSN 742


>gi|239741309 PREDICTED: hypothetical protein XP_002344485 [Homo
           sapiens]
          Length = 4621

 Score = 34.3 bits (77), Expect = 0.39
 Identities = 52/227 (22%), Positives = 98/227 (43%), Gaps = 16/227 (7%)

Query: 249 DQTKPTPLILDEQGRTVDATGKEIELTHR-MPTLKANIRAVK-REQFKQQLKEKPSE--D 304
           D+ +    IL   G T  AT   + ++   + + KA +  ++  E+   QL EK  +  +
Sbjct: 249 DECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLHPQLAEKKQQFRN 308

Query: 305 MESNTFFDPRVSIAPSQRQRRTFKFHDKGKFEKIAQRLRTKAQLEKLQAEISQAAR---- 360
           ++   F         +Q+++  +K+ +     K   R   + + EKL  ++ QA      
Sbjct: 309 LKERCFVTQLAGFLANQQKK--YKYEECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQY 366

Query: 361 KTGIHTSTRLALIAPKKELKEGDIPEI---EWWDSYIIPNGFDLTEENPKREDYFGITNL 417
           K  +H   R  L   +++L+EG        E   + + P+  D ++    +E       L
Sbjct: 367 KVLVHAQER-ELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRL 425

Query: 418 VEHPAQ-LNPPVDNDTPVTLGVYLTKKEQK-KLRRQTRREAQKELQE 462
            +H  Q L+P  DND    + V L +K QK    R+ ++  +KE+ E
Sbjct: 426 AQHLVQKLSPENDNDDDEDVQVELAEKVQKSSAPREMQKAEEKEVPE 472


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.129    0.361 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,600,847
Number of Sequences: 37866
Number of extensions: 1276080
Number of successful extensions: 6657
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 221
Number of HSP's that attempted gapping in prelim test: 6259
Number of HSP's gapped (non-prelim): 678
length of query: 683
length of database: 18,247,518
effective HSP length: 109
effective length of query: 574
effective length of database: 14,120,124
effective search space: 8104951176
effective search space used: 8104951176
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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