Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 4758516

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4758516 hepatoma-derived growth factor isoform a [Homo
sapiens]
         (240 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4758516 hepatoma-derived growth factor isoform a [Homo sapiens]    494   e-140
gi|186928819 hepatoma-derived growth factor isoform b [Homo sapi...   432   e-121
gi|186928821 hepatoma-derived growth factor isoform c [Homo sapi...   431   e-121
gi|110681712 hepatoma derived growth factor-like 1 [Homo sapiens]     249   2e-66
gi|7705320 hepatoma-derived growth factor, related protein 3 [Ho...   204   7e-53
gi|190014588 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo...   185   3e-47
gi|190014586 PC4 and SFRS1 interacting protein 1 isoform 1 [Homo...   185   3e-47
gi|19923653 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo ...   185   3e-47
gi|48255931 hepatoma-derived growth factor-related protein 2 iso...   167   6e-42
gi|14249158 hepatoma-derived growth factor-related protein 2 iso...   167   6e-42
gi|40556376 cytokine-like nuclear factor n-pac [Homo sapiens]          69   4e-12
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom...    64   1e-10
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     51   8e-07
gi|19913356 Wolf-Hirschhorn syndrome candidate 1 protein isoform...    51   1e-06
gi|19913358 Wolf-Hirschhorn syndrome candidate 1 protein isoform...    51   1e-06
gi|6594683 Wolf-Hirschhorn syndrome candidate 1 protein isoform ...    51   1e-06
gi|19913350 Wolf-Hirschhorn syndrome candidate 1 protein isoform...    51   1e-06
gi|19913348 Wolf-Hirschhorn syndrome candidate 1 protein isoform...    51   1e-06
gi|109633019 Wolf-Hirschhorn syndrome candidate 1 protein isofor...    51   1e-06
gi|157738619 smoothelin-like 1 [Homo sapiens]                          49   4e-06
gi|13540523 nucleosomal binding protein 1 [Homo sapiens]               49   5e-06
gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex...    48   9e-06
gi|156104891 general transcription factor IIF, polypeptide 1, 74...    47   1e-05
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]           47   1e-05
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]           47   1e-05
gi|15721939 metastatic lymph node 51 [Homo sapiens]                    47   2e-05
gi|13699811 WHSC1L1 protein isoform long [Homo sapiens]                46   3e-05
gi|13699813 WHSC1L1 protein isoform short [Homo sapiens]               46   3e-05
gi|21237808 SWI/SNF-related matrix-associated actin-dependent re...    45   4e-05
gi|21237805 SWI/SNF-related matrix-associated actin-dependent re...    45   4e-05

>gi|4758516 hepatoma-derived growth factor isoform a [Homo sapiens]
          Length = 240

 Score =  494 bits (1272), Expect = e-140
 Identities = 240/240 (100%), Positives = 240/240 (100%)

Query: 1   MSRSNRQKEYKCGDLVFAKMKGYPHWPARIDEMPEAAVKSTANKYQVFFFGTHETAFLGP 60
           MSRSNRQKEYKCGDLVFAKMKGYPHWPARIDEMPEAAVKSTANKYQVFFFGTHETAFLGP
Sbjct: 1   MSRSNRQKEYKCGDLVFAKMKGYPHWPARIDEMPEAAVKSTANKYQVFFFGTHETAFLGP 60

Query: 61  KDLFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAE 120
           KDLFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAE
Sbjct: 61  KDLFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAE 120

Query: 121 GDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEK 180
           GDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEK
Sbjct: 121 GDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEK 180

Query: 181 EAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAPGIRDHESL 240
           EAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAPGIRDHESL
Sbjct: 181 EAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAPGIRDHESL 240


>gi|186928819 hepatoma-derived growth factor isoform b [Homo
           sapiens]
          Length = 256

 Score =  432 bits (1111), Expect = e-121
 Identities = 212/214 (99%), Positives = 212/214 (99%)

Query: 27  PARIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEKFGKPNKRKGFSEGL 86
           P  IDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEKFGKPNKRKGFSEGL
Sbjct: 43  PHTIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEKFGKPNKRKGFSEGL 102

Query: 87  WEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAK 146
           WEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAK
Sbjct: 103 WEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAK 162

Query: 147 EKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGS 206
           EKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGS
Sbjct: 163 EKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGS 222

Query: 207 GRGPPQEEEEEEDEEEEATKEDAEAPGIRDHESL 240
           GRGPPQEEEEEEDEEEEATKEDAEAPGIRDHESL
Sbjct: 223 GRGPPQEEEEEEDEEEEATKEDAEAPGIRDHESL 256


>gi|186928821 hepatoma-derived growth factor isoform c [Homo
           sapiens]
          Length = 233

 Score =  431 bits (1108), Expect = e-121
 Identities = 212/213 (99%), Positives = 212/213 (99%)

Query: 28  ARIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEKFGKPNKRKGFSEGLW 87
           A IDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEKFGKPNKRKGFSEGLW
Sbjct: 21  AVIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEKFGKPNKRKGFSEGLW 80

Query: 88  EIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKE 147
           EIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKE
Sbjct: 81  EIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKE 140

Query: 148 KNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSG 207
           KNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSG
Sbjct: 141 KNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSG 200

Query: 208 RGPPQEEEEEEDEEEEATKEDAEAPGIRDHESL 240
           RGPPQEEEEEEDEEEEATKEDAEAPGIRDHESL
Sbjct: 201 RGPPQEEEEEEDEEEEATKEDAEAPGIRDHESL 233


>gi|110681712 hepatoma derived growth factor-like 1 [Homo sapiens]
          Length = 251

 Score =  249 bits (635), Expect = 2e-66
 Identities = 141/251 (56%), Positives = 161/251 (64%), Gaps = 28/251 (11%)

Query: 10  YKCGDLVFAKMKGYPHWPARIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEES 69
           YK GDLVFAK+KGY HWPARI+ M +       N+YQVFFFGTHETAFL PK LFPY+E 
Sbjct: 9   YKSGDLVFAKLKGYAHWPARIEHMTQP------NRYQVFFFGTHETAFLSPKRLFPYKEC 62

Query: 70  KEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNA 129
           KEKFGKPNKR+GFS GLWEIENNPTV+AS    + +K   + P PEPEAAEGD DK  +A
Sbjct: 63  KEKFGKPNKRRGFSAGLWEIENNPTVQASDCPLASEKGSGDGPWPEPEAAEGDEDKPTHA 122

Query: 130 EGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKE-------- 181
            G  DE GK   D+P +E  EKG LKR AGD  ED+PKRPKEA   + EE E        
Sbjct: 123 GGGGDELGKPDDDKPTEE--EKGPLKRSAGDPPEDAPKRPKEAAPDQEEEAEAERAAEAE 180

Query: 182 -------AATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKE-----DA 229
                  A  ++ E P  + VE  S PSEPG    PPQ EEEE  EEE A +E      A
Sbjct: 181 RAAAAAAATAVDEESPFLVAVENGSAPSEPGLVCEPPQPEEEELREEEVADEEASQEWHA 240

Query: 230 EAPGIRDHESL 240
           EAPG  D +SL
Sbjct: 241 EAPGGGDRDSL 251


>gi|7705320 hepatoma-derived growth factor, related protein 3 [Homo
           sapiens]
          Length = 203

 Score =  204 bits (518), Expect = 7e-53
 Identities = 110/221 (49%), Positives = 138/221 (62%), Gaps = 23/221 (10%)

Query: 6   RQKEYKCGDLVFAKMKGYPHWPARIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFP 65
           R +EYK GDLVFAKMKGYPHWPARIDE+PE AVK  ANKY +FFFGTHETAFLGPKDLFP
Sbjct: 5   RPREYKAGDLVFAKMKGYPHWPARIDELPEGAVKPPANKYPIFFFGTHETAFLGPKDLFP 64

Query: 66  YEESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDK 125
           Y+E K+KFGK NKRKGF+EGLWEIENNP VK +GYQ+ Q++S          ++E +G+ 
Sbjct: 65  YKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQS----------SSETEGEG 114

Query: 126 KGNAEGSSDEEG-KLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAAT 184
              A+ SS+EEG ++  D   K KNEK   KR+       S K  K++    G+E +   
Sbjct: 115 GNTADASSEEEGDRVEEDGKGKRKNEKAGSKRKKS---YTSKKSSKQSRKSPGDEDDKDC 171

Query: 185 LEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEAT 225
            E         E+N + SE G      +    +  +  E T
Sbjct: 172 KE---------EENKSSSEGGDAGNDTRNTTSDLQKTSEGT 203


>gi|190014588 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo
           sapiens]
          Length = 530

 Score =  185 bits (469), Expect = 3e-47
 Identities = 112/265 (42%), Positives = 154/265 (58%), Gaps = 41/265 (15%)

Query: 8   KEYKCGDLVFAKMKGYPHWPARIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYE 67
           +++K GDL+FAKMKGYPHWPAR+DE+P+ AVK   NK  +FFFGTHETAFLGPKD+FPY 
Sbjct: 3   RDFKPGDLIFAKMKGYPHWPARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPKDIFPYS 62

Query: 68  ESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKK----SCVEEPEPEPEAAEGDG 123
           E+KEK+GKPNKRKGF+EGLWEI+NNP VK S  Q++ K+    S VE  E E   ++ D 
Sbjct: 63  ENKEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDT 122

Query: 124 DKKGNAEGSSDEEGKLVID--------EPAKEKNEKGALKRRAGDL--------LEDSPK 167
           D   + E +S+E+    +D           K K EK      AG +        L+ SPK
Sbjct: 123 D---HEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPK 179

Query: 168 RPKEA------ENPEGEEKEAATLEVERPLPME----VEKNSTPSEPGSGRGP---PQEE 214
           R + A        P G  K      V++P P E     E++ +  +    + P   P+++
Sbjct: 180 RGRPAATEVKIPKPRGRPK-----MVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKD 234

Query: 215 EEEEDEEEEATKEDAEAPGIRDHES 239
           EE + EE++  KE  +  G ++ ES
Sbjct: 235 EEGQKEEDKPRKEPDKKEGKKEVES 259



 Score = 32.0 bits (71), Expect = 0.49
 Identities = 26/116 (22%), Positives = 51/116 (43%), Gaps = 10/116 (8%)

Query: 67  EESKEKFGKPNKRKGFSEGLWEIEN-NPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDK 125
           EE +++  KP K     EG  E+E+    +  +G  S+       + E E +  EG+  +
Sbjct: 235 EEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGVTST------SDSEEEGDDQEGEKKR 288

Query: 126 KGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKE 181
           KG     +     ++  +  KE  ++   KR+  + +E   +   E + PE ++ E
Sbjct: 289 KGGRNFQTAHRRNMLKGQHEKEAADR---KRKQEEQMETEQQNKDEGKKPEVKKVE 341


>gi|190014586 PC4 and SFRS1 interacting protein 1 isoform 1 [Homo
           sapiens]
          Length = 333

 Score =  185 bits (469), Expect = 3e-47
 Identities = 112/265 (42%), Positives = 154/265 (58%), Gaps = 41/265 (15%)

Query: 8   KEYKCGDLVFAKMKGYPHWPARIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYE 67
           +++K GDL+FAKMKGYPHWPAR+DE+P+ AVK   NK  +FFFGTHETAFLGPKD+FPY 
Sbjct: 3   RDFKPGDLIFAKMKGYPHWPARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPKDIFPYS 62

Query: 68  ESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKK----SCVEEPEPEPEAAEGDG 123
           E+KEK+GKPNKRKGF+EGLWEI+NNP VK S  Q++ K+    S VE  E E   ++ D 
Sbjct: 63  ENKEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDT 122

Query: 124 DKKGNAEGSSDEEGKLVID--------EPAKEKNEKGALKRRAGDL--------LEDSPK 167
           D   + E +S+E+    +D           K K EK      AG +        L+ SPK
Sbjct: 123 D---HEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPK 179

Query: 168 RPKEA------ENPEGEEKEAATLEVERPLPME----VEKNSTPSEPGSGRGP---PQEE 214
           R + A        P G  K      V++P P E     E++ +  +    + P   P+++
Sbjct: 180 RGRPAATEVKIPKPRGRPK-----MVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKD 234

Query: 215 EEEEDEEEEATKEDAEAPGIRDHES 239
           EE + EE++  KE  +  G ++ ES
Sbjct: 235 EEGQKEEDKPRKEPDKKEGKKEVES 259


>gi|19923653 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo
           sapiens]
          Length = 530

 Score =  185 bits (469), Expect = 3e-47
 Identities = 112/265 (42%), Positives = 154/265 (58%), Gaps = 41/265 (15%)

Query: 8   KEYKCGDLVFAKMKGYPHWPARIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYE 67
           +++K GDL+FAKMKGYPHWPAR+DE+P+ AVK   NK  +FFFGTHETAFLGPKD+FPY 
Sbjct: 3   RDFKPGDLIFAKMKGYPHWPARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPKDIFPYS 62

Query: 68  ESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKK----SCVEEPEPEPEAAEGDG 123
           E+KEK+GKPNKRKGF+EGLWEI+NNP VK S  Q++ K+    S VE  E E   ++ D 
Sbjct: 63  ENKEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDT 122

Query: 124 DKKGNAEGSSDEEGKLVID--------EPAKEKNEKGALKRRAGDL--------LEDSPK 167
           D   + E +S+E+    +D           K K EK      AG +        L+ SPK
Sbjct: 123 D---HEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPK 179

Query: 168 RPKEA------ENPEGEEKEAATLEVERPLPME----VEKNSTPSEPGSGRGP---PQEE 214
           R + A        P G  K      V++P P E     E++ +  +    + P   P+++
Sbjct: 180 RGRPAATEVKIPKPRGRPK-----MVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKD 234

Query: 215 EEEEDEEEEATKEDAEAPGIRDHES 239
           EE + EE++  KE  +  G ++ ES
Sbjct: 235 EEGQKEEDKPRKEPDKKEGKKEVES 259



 Score = 32.0 bits (71), Expect = 0.49
 Identities = 26/116 (22%), Positives = 51/116 (43%), Gaps = 10/116 (8%)

Query: 67  EESKEKFGKPNKRKGFSEGLWEIEN-NPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDK 125
           EE +++  KP K     EG  E+E+    +  +G  S+       + E E +  EG+  +
Sbjct: 235 EEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGVTST------SDSEEEGDDQEGEKKR 288

Query: 126 KGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKE 181
           KG     +     ++  +  KE  ++   KR+  + +E   +   E + PE ++ E
Sbjct: 289 KGGRNFQTAHRRNMLKGQHEKEAADR---KRKQEEQMETEQQNKDEGKKPEVKKVE 341


>gi|48255931 hepatoma-derived growth factor-related protein 2
           isoform 1 [Homo sapiens]
          Length = 671

 Score =  167 bits (424), Expect = 6e-42
 Identities = 91/214 (42%), Positives = 124/214 (57%), Gaps = 16/214 (7%)

Query: 10  YKCGDLVFAKMKGYPHWPARIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEES 69
           +K GDLVFAKMKGYPHWPARID++ + AVK   NKY +FFFGTHETAFLGPKDLFPY++ 
Sbjct: 5   FKPGDLVFAKMKGYPHWPARIDDIADGAVKPPPNKYPIFFFGTHETAFLGPKDLFPYDKC 64

Query: 70  KEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEG-DGDKKGN 128
           K+K+GKPNKRKGF+EGLWEI+NNP    + Y +    S  +   PE   A+G D D+   
Sbjct: 65  KDKYGKPNKRKGFNEGLWEIQNNP---HASYSAPPPVSSSDSEAPEANPADGSDADEDDE 121

Query: 129 AEG--------SSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEK 180
             G        ++    ++  D  + + ++   LKR+   L     KR ++A +   +  
Sbjct: 122 DRGVMAVTAVTATAASDRMESDSDSDKSSDNSGLKRKTPALKMSVSKRARKASSDLDQAS 181

Query: 181 EAATLEVERPLPMEVEKNS----TPSEPGSGRGP 210
            + + E       E EK S    TP +  + R P
Sbjct: 182 VSPSEEENSESSSESEKTSDQDFTPEKKAAVRAP 215



 Score = 38.1 bits (87), Expect = 0.007
 Identities = 34/140 (24%), Positives = 56/140 (40%), Gaps = 13/140 (9%)

Query: 96  KASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALK 155
           KA     S  K+  +  +PEP A         ++  SSD +  +      ++  EK   K
Sbjct: 227 KAPSASDSDSKADSDGAKPEPVAMARSASSSSSSSSSSDSDVSVKKPPRGRKPAEKPLPK 286

Query: 156 RRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEE 215
            R         ++PK    P     ++ + EV+R    +    +   E  + R   QEEE
Sbjct: 287 PRG--------RKPKPERPPSSSSSDSDSDEVDRISEWKRRDEARRRELEARRRREQEEE 338

Query: 216 -----EEEDEEEEATKEDAE 230
                E+E EE+E  +E A+
Sbjct: 339 LRRLREQEKEEKERRRERAD 358



 Score = 35.4 bits (80), Expect = 0.044
 Identities = 31/126 (24%), Positives = 51/126 (40%), Gaps = 6/126 (4%)

Query: 111 EPEPEPEAAEGDGDKKGN---AEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPK 167
           +PE  P ++  D D       +E    +E +    E  + + ++  L+R      E+  +
Sbjct: 293 KPERPPSSSSSDSDSDEVDRISEWKRRDEARRRELEARRRREQEEELRRLREQEKEEKER 352

Query: 168 RPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEE-EDEEEEATK 226
           R + A+  E E     +   E  L  + E        G GRGPP   + E E E E   K
Sbjct: 353 RRERADRGEAERGSGGSSGDE--LREDDEPVKKRGRKGRGRGPPSSSDSEPEAELEREAK 410

Query: 227 EDAEAP 232
           + A+ P
Sbjct: 411 KSAKKP 416



 Score = 35.0 bits (79), Expect = 0.058
 Identities = 38/141 (26%), Positives = 60/141 (42%), Gaps = 27/141 (19%)

Query: 110 EEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKG---------------AL 154
           EE E   E A+    ++G+   S DE  +   DEP K++  KG                L
Sbjct: 348 EEKERRRERADRGEAERGSGGSSGDELRE--DDEPVKKRGRKGRGRGPPSSSDSEPEAEL 405

Query: 155 KRRAGDLLEDSPKRPKE-----AENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRG 209
           +R A    + S K+P+      A  P  +EK     E ++  P++VE+    SE G    
Sbjct: 406 EREA----KKSAKKPQSSSTEPARKPGQKEKRVRPEEKQQAKPVKVERTRKRSE-GFSMD 460

Query: 210 PPQEEEEEEDEEEEATKEDAE 230
              E+++E   EE+  K  +E
Sbjct: 461 RKVEKKKEPSVEEKLQKLHSE 481



 Score = 32.0 bits (71), Expect = 0.49
 Identities = 24/98 (24%), Positives = 38/98 (38%), Gaps = 16/98 (16%)

Query: 143 EPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPS 202
           E  ++ N+ G  K +A + L       +EA   + E+K +  L                S
Sbjct: 556 EAVQKVNKAGMEKEKAEEKLAGEELAGEEAPQEKAEDKPSTDL----------------S 599

Query: 203 EPGSGRGPPQEEEEEEDEEEEATKEDAEAPGIRDHESL 240
            P +G    Q+ E  ED+E E  ++  E P     E L
Sbjct: 600 APVNGEATSQKGESAEDKEHEEGRDSEEGPRCGSSEDL 637


>gi|14249158 hepatoma-derived growth factor-related protein 2
           isoform 2 [Homo sapiens]
          Length = 670

 Score =  167 bits (424), Expect = 6e-42
 Identities = 91/214 (42%), Positives = 124/214 (57%), Gaps = 16/214 (7%)

Query: 10  YKCGDLVFAKMKGYPHWPARIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEES 69
           +K GDLVFAKMKGYPHWPARID++ + AVK   NKY +FFFGTHETAFLGPKDLFPY++ 
Sbjct: 5   FKPGDLVFAKMKGYPHWPARIDDIADGAVKPPPNKYPIFFFGTHETAFLGPKDLFPYDKC 64

Query: 70  KEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEG-DGDKKGN 128
           K+K+GKPNKRKGF+EGLWEI+NNP    + Y +    S  +   PE   A+G D D+   
Sbjct: 65  KDKYGKPNKRKGFNEGLWEIQNNP---HASYSAPPPVSSSDSEAPEANPADGSDADEDDE 121

Query: 129 AEG--------SSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEK 180
             G        ++    ++  D  + + ++   LKR+   L     KR ++A +   +  
Sbjct: 122 DRGVMAVTAVTATAASDRMESDSDSDKSSDNSGLKRKTPALKMSVSKRARKASSDLDQAS 181

Query: 181 EAATLEVERPLPMEVEKNS----TPSEPGSGRGP 210
            + + E       E EK S    TP +  + R P
Sbjct: 182 VSPSEEENSESSSESEKTSDQDFTPEKKAAVRAP 215



 Score = 38.1 bits (87), Expect = 0.007
 Identities = 34/140 (24%), Positives = 56/140 (40%), Gaps = 13/140 (9%)

Query: 96  KASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALK 155
           KA     S  K+  +  +PEP A         ++  SSD +  +      ++  EK   K
Sbjct: 227 KAPSASDSDSKADSDGAKPEPVAMARSASSSSSSSSSSDSDVSVKKPPRGRKPAEKPLPK 286

Query: 156 RRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEE 215
            R         ++PK    P     ++ + EV+R    +    +   E  + R   QEEE
Sbjct: 287 PRG--------RKPKPERPPSSSSSDSDSDEVDRISEWKRRDEARRRELEARRRREQEEE 338

Query: 216 -----EEEDEEEEATKEDAE 230
                E+E EE+E  +E A+
Sbjct: 339 LRRLREQEKEEKERRRERAD 358



 Score = 35.4 bits (80), Expect = 0.044
 Identities = 31/126 (24%), Positives = 51/126 (40%), Gaps = 6/126 (4%)

Query: 111 EPEPEPEAAEGDGDKKGN---AEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPK 167
           +PE  P ++  D D       +E    +E +    E  + + ++  L+R      E+  +
Sbjct: 293 KPERPPSSSSSDSDSDEVDRISEWKRRDEARRRELEARRRREQEEELRRLREQEKEEKER 352

Query: 168 RPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEE-EDEEEEATK 226
           R + A+  E E     +   E  L  + E        G GRGPP   + E E E E   K
Sbjct: 353 RRERADRGEAERGSGGSSGDE--LREDDEPVKKRGRKGRGRGPPSSSDSEPEAELEREAK 410

Query: 227 EDAEAP 232
           + A+ P
Sbjct: 411 KSAKKP 416



 Score = 35.0 bits (79), Expect = 0.058
 Identities = 38/141 (26%), Positives = 60/141 (42%), Gaps = 27/141 (19%)

Query: 110 EEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKG---------------AL 154
           EE E   E A+    ++G+   S DE  +   DEP K++  KG                L
Sbjct: 348 EEKERRRERADRGEAERGSGGSSGDELRE--DDEPVKKRGRKGRGRGPPSSSDSEPEAEL 405

Query: 155 KRRAGDLLEDSPKRPKE-----AENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRG 209
           +R A    + S K+P+      A  P  +EK     E ++  P++VE+    SE G    
Sbjct: 406 EREA----KKSAKKPQSSSTEPARKPGQKEKRVRPEEKQQAKPVKVERTRKRSE-GFSMD 460

Query: 210 PPQEEEEEEDEEEEATKEDAE 230
              E+++E   EE+  K  +E
Sbjct: 461 RKVEKKKEPSVEEKLQKLHSE 481



 Score = 32.0 bits (71), Expect = 0.49
 Identities = 24/98 (24%), Positives = 38/98 (38%), Gaps = 16/98 (16%)

Query: 143 EPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPS 202
           E  ++ N+ G  K +A + L       +EA   + E+K +  L                S
Sbjct: 556 EAVQKVNKAGMEKEKAEEKLAGEELAGEEAPQEKAEDKPSTDL----------------S 599

Query: 203 EPGSGRGPPQEEEEEEDEEEEATKEDAEAPGIRDHESL 240
            P +G    Q+ E  ED+E E  ++  E P     E L
Sbjct: 600 APVNGEATSQKGESAEDKEHEEGRDSEEGPRCGSSEDL 637



 Score = 28.1 bits (61), Expect = 7.1
 Identities = 38/157 (24%), Positives = 58/157 (36%), Gaps = 25/157 (15%)

Query: 16  VFAKMKGYPHWPARIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEKFGK 75
           V A +K    + A  D M +AA   T  K +V          LGPK     + +K    K
Sbjct: 519 VVATLKKIRRYKANKDVMEKAAEVYTRLKSRV----------LGPKIEAVQKVNKAGMEK 568

Query: 76  PNKRKGFSEGLWEIENNPTVKA------------SGYQSSQKKSCVEEPEPEPEAAEGDG 123
               +  +      E  P  KA            +G  +SQK    E+ E E      +G
Sbjct: 569 EKAEEKLAGEELAGEEAPQEKAEDKPSTDLSAPVNGEATSQKGESAEDKEHEEGRDSEEG 628

Query: 124 DKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGD 160
            + G++E   D      +D P  ++ E+   +R  GD
Sbjct: 629 PRCGSSEDLHDVREGPDLDRPGSDRQER---ERARGD 662


>gi|40556376 cytokine-like nuclear factor n-pac [Homo sapiens]
          Length = 553

 Score = 68.9 bits (167), Expect = 4e-12
 Identities = 64/215 (29%), Positives = 94/215 (43%), Gaps = 21/215 (9%)

Query: 11  KCGDLVFAKMKGYPHWPARIDEMPEAAVKSTANK-YQVFFFGTHETAFLGPKDLFPYEES 69
           + GDLV+ K+  YP WP +I   P+   K    K + V FFGT + A++  + L PY   
Sbjct: 7   RLGDLVWGKLGRYPPWPGKIVNPPKDLKKPRGKKCFFVKFFGTEDHAWIKVEQLKPYHAH 66

Query: 70  KEKFGKPNKRKGFSEGLWEIEN-----NPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGD 124
           KE+  K NK K F + +  +E          + S + SS  K+     E       GD  
Sbjct: 67  KEEMIKINKGKRFQQAVDAVEEFLRRAKGKDQTSSHNSSDDKNRRNSSEERSRPNSGDEK 126

Query: 125 KK-GNAEGSSDE---EGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEE- 179
           +K   +EG   +   EGK  +   + E+  K  LKR      E SP+  K    P+ E+ 
Sbjct: 127 RKLSLSEGKVKKNMGEGKKRVSSGSSERGSKSPLKRAQ----EQSPR--KRGRPPKDEKD 180

Query: 180 ---KEAATLEVERPLPMEVEK-NSTPSEPGSGRGP 210
               E++T++     PM   K   T SEP     P
Sbjct: 181 LTIPESSTVKGMMAGPMAAFKWQPTASEPVKDADP 215


>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
           sapiens]
          Length = 1152

 Score = 63.9 bits (154), Expect = 1e-10
 Identities = 64/213 (30%), Positives = 90/213 (42%), Gaps = 29/213 (13%)

Query: 22  GYPHWPARIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEKFGKPNKRKG 81
           G  HW    DE  E   K           G  E    G K+L   EE K++ G+  ++K 
Sbjct: 665 GAEHWQ---DEEREKGEKDKGR-------GEMERPGEGEKELAEKEEWKKRDGEEQEQKE 714

Query: 82  FSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVI 141
             +G  + E N  ++  G          EE   E E  EGD +++   EG   EEG+   
Sbjct: 715 REQG-HQKERNQEMEEGG----------EEEHGEGEEEEGDREEEEEKEGEGKEEGE--- 760

Query: 142 DEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTP 201
            E  + + EK   +R+  +      K  +E +  EGEE+E      E+    EVE     
Sbjct: 761 GEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVE----G 816

Query: 202 SEPGSGRGPPQEEEEE-EDEEEEATKEDAEAPG 233
            E   G+G  +EEEEE E EEEE   E+ E  G
Sbjct: 817 GEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEG 849



 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 52/173 (30%), Positives = 78/173 (45%), Gaps = 15/173 (8%)

Query: 67   EESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKK 126
            EE +E  G+    +G  EG  E          G    +++    E E E E  EG+G+++
Sbjct: 860  EEGEEGEGEEEGEEGEGEGEEE---------EGEGEGEEEG---EGEGEEEEGEGEGEEE 907

Query: 127  GNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLE 186
            G  EG  +EEG+   +E  +E   +G  +   G+  +   +  +E    EGEE+E    E
Sbjct: 908  GEGEGE-EEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEG-E 965

Query: 187  VERPLPMEVEKNSTPSEPGSGRGPPQEEE-EEEDEEEEATKEDAEAPGIRDHE 238
             E     E E+     E   G G  +EEE EEE EEE   +E+ E  G  + E
Sbjct: 966  GEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEE 1018



 Score = 49.3 bits (116), Expect = 3e-06
 Identities = 45/166 (27%), Positives = 71/166 (42%), Gaps = 11/166 (6%)

Query: 68   ESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKG 127
            E +E  GK  +     EG  E E        G    +++    E E E E  EG+G+++G
Sbjct: 913  EEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEE--GEWEGEEEEGEGEGEEEG 970

Query: 128  NAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEV 187
              EG   EEG    +   +E+  +G  +   G+  E+  +  +  E  EGE +E    EV
Sbjct: 971  EGEG---EEG----EGEGEEEEGEGEGEEEEGE--EEGEEEGEGEEEGEGEGEEEEEGEV 1021

Query: 188  ERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAPG 233
            E  +  E  +     E G   G  +E+E E +E     +E+ E  G
Sbjct: 1022 EGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEG 1067



 Score = 48.5 bits (114), Expect = 5e-06
 Identities = 52/171 (30%), Positives = 75/171 (43%), Gaps = 15/171 (8%)

Query: 67  EESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKK 126
           EE  +  G+  + +G  E   E E    V+    +  + +   EE E E E  EG+G+++
Sbjct: 789 EEGDQGEGEEEETEGRGE---EKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEE 845

Query: 127 GNAEGSSDE-EGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATL 185
              EG  +E EGK   +    E  E+G      G+  E   +  +E E  EGEE+E    
Sbjct: 846 -EGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEG-EGEEEEGEG- 902

Query: 186 EVERPLPMEVEKNSTPSEPGSGRGPPQEEE---EEEDEEEEATKEDAEAPG 233
           E E     E  +     E G G+G  + EE   E E+EE E   ED E  G
Sbjct: 903 EGE-----EEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEG 948



 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 55/191 (28%), Positives = 79/191 (41%), Gaps = 31/191 (16%)

Query: 67   EESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGD-- 124
            EE +E  G+  + +G  EG  E E        G +   +    EE E E E  EG+G   
Sbjct: 869  EEGEEGEGEGEEEEGEGEGEEEGEGE------GEEEEGEGEGEEEGEGEGEEEEGEGKGE 922

Query: 125  ---KKGNAEGSSDE---EGKLVIDEPAKEKNE-KGALKRRAGDLLEDSPKRPKEAENPEG 177
               ++G  EG  +E   EG+    E  +E+ E +G  +   G+  E+     +E E  EG
Sbjct: 923  EEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEG-EG 981

Query: 178  EEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEE--------------EEDE-EE 222
            EE+E      E     E E+     E G G G  +EE E              EE+E EE
Sbjct: 982  EEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEE 1041

Query: 223  EATKEDAEAPG 233
            E  + + E  G
Sbjct: 1042 EGEEREKEGEG 1052



 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 49/174 (28%), Positives = 73/174 (41%), Gaps = 19/174 (10%)

Query: 67  EESKEKFG-KPNKRKGFSEGLWEIE-NNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGD 124
           E  +EK G + +K  G  E   E+E N   VK  G +  + +   ++   + E +EG   
Sbjct: 585 EIPEEKEGAEDSKGNGIEEQ--EVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGKAK 642

Query: 125 KKGNAEGSSD-------EEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEG 177
             G AE   +       EEG    +    E+ EKG   +  G++        + AE  E 
Sbjct: 643 SVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEW 702

Query: 178 EEKEAATLEV-ERPLPMEVEKNSTPSEPGS---GRGPPQEEEEEEDEEEEATKE 227
           ++++    E  ER    + E+N    E G    G G    EEEE D EEE  KE
Sbjct: 703 KKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEG----EEEEGDREEEEEKE 752



 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 46/166 (27%), Positives = 71/166 (42%), Gaps = 23/166 (13%)

Query: 67   EESKEKFGKPNKRKGFSE-GLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDK 125
            EE  E  G+  + +G  E G WE E     +  G +  + +    E E E E  EG+G++
Sbjct: 934  EEEGEGEGEDGEGEGEEEEGEWEGEEEEG-EGEGEEEGEGEGEEGEGEGEEEEGEGEGEE 992

Query: 126  K-GNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAAT 184
            + G  EG  + EG+    E   E+ E+G ++        +  +   E E  EGEE     
Sbjct: 993  EEGEEEGEEEGEGE-EEGEGEGEEEEEGEVEGEV-----EGEEGEGEGEEEEGEE----- 1041

Query: 185  LEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAE 230
                     E E+     E    R   +EEEEEE + +E  +E+ E
Sbjct: 1042 ---------EGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENE 1078



 Score = 36.6 bits (83), Expect = 0.020
 Identities = 36/133 (27%), Positives = 60/133 (45%), Gaps = 6/133 (4%)

Query: 67   EESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKK 126
            E   E+ G+    +G  EG  E E     +  G +   ++   EE E E E  EG+G+++
Sbjct: 963  EGEGEEEGEGEGEEGEGEG--EEEEG---EGEGEEEEGEEEGEEEGEGEEEG-EGEGEEE 1016

Query: 127  GNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLE 186
               E   + EG+    E  +E+ E+   +R      E++ +  +E E  EG+ +E    E
Sbjct: 1017 EEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEE 1076

Query: 187  VERPLPMEVEKNS 199
             ER    E +K S
Sbjct: 1077 NERQDGEEYKKVS 1089


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 51.2 bits (121), Expect = 8e-07
 Identities = 49/179 (27%), Positives = 83/179 (46%), Gaps = 15/179 (8%)

Query: 68  ESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGD--- 124
           +S EK   P K +  S    E   +P VK       + KS V+E    PE A+       
Sbjct: 703 KSPEKAKSPVKEEAKSP---EKAKSP-VKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKT 758

Query: 125 ---KKGNAEGSSDEEGKLVIDE-PAKEKN---EKGALKRRAGDLLEDSPKRPKEAENPEG 177
              K   A+  + EE +   D+ P K K+   E+     +A   L++  K P E E P+ 
Sbjct: 759 LDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAP-EKEIPKK 817

Query: 178 EEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAPGIRD 236
           EE ++   E E+P  ++V++    +E       P+ EE+++ ++EEA K++A  P + +
Sbjct: 818 EEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEE 876



 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 44/188 (23%), Positives = 82/188 (43%), Gaps = 22/188 (11%)

Query: 67  EESKEKFGKPNK--RKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDG- 123
           +E+KE+ GK  +   +  +EG  E   +P  + +     + KS V+E    P  A+    
Sbjct: 476 KEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEK 535

Query: 124 -DKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKR-------------RAGDLLEDSPKRP 169
            + K  AE  S E+ K    E AK   E  + ++             +A    ++  K P
Sbjct: 536 EEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSP 595

Query: 170 KEAENPEG-----EEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEA 224
            EA++PE      +E+  +  E + P+  E +  +    P   + P +EE +  ++ +  
Sbjct: 596 AEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSP 655

Query: 225 TKEDAEAP 232
            KE+A++P
Sbjct: 656 EKEEAKSP 663



 Score = 48.5 bits (114), Expect = 5e-06
 Identities = 39/138 (28%), Positives = 62/138 (44%), Gaps = 7/138 (5%)

Query: 101 QSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGD 160
           +S +K   VE+ E E    E   ++    E  ++EE K   +E  KE+ E G  +   G 
Sbjct: 439 KSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEE-EGGEEEEAEGG 497

Query: 161 LLEDSPKRPKEAENPEGEEKEAATLEVERPLPM---EVEKNSTPSE---PGSGRGPPQEE 214
             E      +EA +PE E K     E + P      E E+  +P+E   P   + P +EE
Sbjct: 498 EEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEE 557

Query: 215 EEEEDEEEEATKEDAEAP 232
            +   E +   KE+A++P
Sbjct: 558 AKSPPEAKSPEKEEAKSP 575



 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 40/135 (29%), Positives = 64/135 (47%), Gaps = 20/135 (14%)

Query: 110 EEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAK-EKNEKGALKRRAGDLLEDSPKR 168
           E+   E E  E +G ++  AEG  +E      +E A  EK  K  +K  A        K 
Sbjct: 475 EKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEA--------KS 526

Query: 169 PKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQ----EEEEEEDEEEEA 224
           P EA++PE EE ++   EV+ P     EK  +P++    + PP+    E+EE +   E  
Sbjct: 527 PAEAKSPEKEEAKSPA-EVKSP-----EKAKSPAKE-EAKSPPEAKSPEKEEAKSPAEVK 579

Query: 225 TKEDAEAPGIRDHES 239
           + E A++P   + +S
Sbjct: 580 SPEKAKSPAKEEAKS 594



 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 48/200 (24%), Positives = 78/200 (39%), Gaps = 36/200 (18%)

Query: 67  EESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKK 126
           EE+K      +  K  S    E ++ P  K+   +  + KS  E   PE   +    + K
Sbjct: 536 EEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSP--EKEEAKSPAEVKSPEKAKSPAKEEAK 593

Query: 127 GNAEGSSDEEGKLVIDEPAKEKNE-KGALKRRAGDLLE------------DSPKRPKEAE 173
             AE  S E+ K  + E AK   E K  +K  A    E            +  K P++A+
Sbjct: 594 SPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAK 653

Query: 174 NPEGEE-----KEAATLEVERPLPMEV-----------EKNSTP-----SEPGSGRGPPQ 212
           +PE EE     K  + ++ E   P +            EK  +P       P   + P +
Sbjct: 654 SPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVK 713

Query: 213 EEEEEEDEEEEATKEDAEAP 232
           EE +  ++ +   KE+A+ P
Sbjct: 714 EEAKSPEKAKSPVKEEAKTP 733



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 41/176 (23%), Positives = 72/176 (40%), Gaps = 18/176 (10%)

Query: 68  ESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKG 127
           +S EK   P K +  S      E     KA      + KS  E   P  E A+   + K 
Sbjct: 579 KSPEKAKSPAKEEAKSPA----EAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKS 634

Query: 128 NAEGSSDEEGKLVIDEPAKE-KNEKGALKRRAGDLLEDSPKRPKEAENP-----EGEEKE 181
             +  S  + +    E AK  + E+     +A   ++   K P++A++P     +  EK 
Sbjct: 635 PEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKA 694

Query: 182 AATLEVERPLPMEVEKNSTP-----SEPGSGRGPPQEEEEEEDEEEEATKEDAEAP 232
            + ++ E   P   EK  +P       P   + P +EE +  ++ +   KE+A++P
Sbjct: 695 KSPVKEEAKSP---EKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSP 747



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 48/212 (22%), Positives = 81/212 (38%), Gaps = 47/212 (22%)

Query: 68  ESKEKFGKPNKRKGFS--EGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDK 125
           +S EK   P K +  S  E    ++      A      + KS  +E    PE A+    +
Sbjct: 599 KSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKE 658

Query: 126 KG------------------------NAEGSSDEEGKLVIDEPAKEK-------NEKGAL 154
           +                          AE  S E+ K  + E AK          E+   
Sbjct: 659 EAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKS 718

Query: 155 KRRAGDLLEDSPKRPKEAENPEGEE----------KEAATLEVERP---LPMEVEKNSTP 201
             +A   +++  K P++A++P  EE          ++A TL+V+ P    P + E  S  
Sbjct: 719 PEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPA 778

Query: 202 SE-PGSGRGPPQEEEEEEDEEEEATKEDAEAP 232
            + P   + P +EE +  ++ +   KEDA+AP
Sbjct: 779 DKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAP 810



 Score = 37.7 bits (86), Expect = 0.009
 Identities = 49/216 (22%), Positives = 86/216 (39%), Gaps = 17/216 (7%)

Query: 28  ARIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEE---SKEKFGKPNKRKGFSE 84
           A+  E  ++ VK  A   +       E A    K   P +E   S EK   P K K    
Sbjct: 702 AKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDV 761

Query: 85  GLWEIENNPTVKASGYQSS---QKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVI 141
              E +     +A         + KS V+E    PE A+    +   A    +   K  +
Sbjct: 762 KSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAP-EKEIPKKEEV 820

Query: 142 DEPAKEKNEKGALK-----RRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVE 196
             P KE+ +   +K     ++A +  E +P  PK  E  + +++EA   E  +P   +VE
Sbjct: 821 KSPVKEEEKPQEVKVKEPPKKAEE--EKAPATPKTEEKKDSKKEEAPKKEAPKP---KVE 875

Query: 197 KNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAP 232
           +   P+         + ++EE +++++    + EAP
Sbjct: 876 EKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAP 911



 Score = 34.3 bits (77), Expect = 0.099
 Identities = 31/142 (21%), Positives = 65/142 (45%), Gaps = 13/142 (9%)

Query: 101 QSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGD 160
           ++ +KK   +E  P+ EA +   ++K        +E K+      + K E+   K++   
Sbjct: 852 KTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKV------EAKKEEAEDKKKVPT 905

Query: 161 LLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGR--GPPQEEEEEE 218
             +++P + +  E+ + +EK     EV +  P +  K   PS+P   +   P +++ +EE
Sbjct: 906 PEKEAPAKVEVKEDAKPKEK----TEVAKKEPDDA-KAKEPSKPAEKKEAAPEKKDTKEE 960

Query: 219 DEEEEATKEDAEAPGIRDHESL 240
             ++   K   EA    D ++L
Sbjct: 961 KAKKPEEKPKTEAKAKEDDKTL 982



 Score = 28.9 bits (63), Expect = 4.2
 Identities = 17/76 (22%), Positives = 31/76 (40%)

Query: 103  SQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLL 162
            ++KK    E +   E      ++K   E  + E+ K +  EP+K K EK           
Sbjct: 945  AEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKD 1004

Query: 163  EDSPKRPKEAENPEGE 178
               P++  E +  +G+
Sbjct: 1005 SKPPEKATEDKAAKGK 1020



 Score = 28.5 bits (62), Expect = 5.4
 Identities = 23/77 (29%), Positives = 34/77 (44%), Gaps = 7/77 (9%)

Query: 163 EDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEE 222
           E + +  KEA+  EG+E+E    E E     E E  S P+E  +       E+E +   +
Sbjct: 469 EVTEEEEKEAKEEEGKEEEGG--EEEEAEGGEEETKSPPAEEAAS-----PEKEAKSPVK 521

Query: 223 EATKEDAEAPGIRDHES 239
           E  K  AEA      E+
Sbjct: 522 EEAKSPAEAKSPEKEEA 538


>gi|19913356 Wolf-Hirschhorn syndrome candidate 1 protein isoform 3
           [Homo sapiens]
          Length = 647

 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 56/219 (25%), Positives = 94/219 (42%), Gaps = 16/219 (7%)

Query: 9   EYKCGDLVFAKMKGYPHWPARIDEMP-------EAAVKSTANKYQVFFFG-THETAFLGP 60
           +Y  GDLV++K+ GYP WP  +   P           K +A +Y V FFG   E A++  
Sbjct: 219 KYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFE 278

Query: 61  KDLFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVK-ASGYQSSQKKSCVEEPEPEPEAA 119
           K L  + E + +F K  +     +   + E    +K  SG   +Q +  + + E   EAA
Sbjct: 279 KSLVAF-EGEGQFEKLCQESA-KQAPTKAEKIKLLKPISGKLRAQWEMGIVQAE---EAA 333

Query: 120 EGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEE 179
               +++  A+ +    G  +   P   K E G      G++ E S    + AENP+   
Sbjct: 334 SMSVEER-KAKFTFLYVGDQLHLNPQVAK-EAGIAAESLGEMAESSGVSEEAAENPKSVR 391

Query: 180 KEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEE 218
           +E   ++  R   +     +  S P  G+  PQ+  E +
Sbjct: 392 EECIPMKRRRRAKLCSSAETLESHPDIGKSTPQKTAEAD 430


>gi|19913358 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
           [Homo sapiens]
          Length = 1365

 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 56/219 (25%), Positives = 94/219 (42%), Gaps = 16/219 (7%)

Query: 9   EYKCGDLVFAKMKGYPHWPARIDEMP-------EAAVKSTANKYQVFFFG-THETAFLGP 60
           +Y  GDLV++K+ GYP WP  +   P           K +A +Y V FFG   E A++  
Sbjct: 219 KYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFE 278

Query: 61  KDLFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVK-ASGYQSSQKKSCVEEPEPEPEAA 119
           K L  + E + +F K  +     +   + E    +K  SG   +Q +  + + E   EAA
Sbjct: 279 KSLVAF-EGEGQFEKLCQESA-KQAPTKAEKIKLLKPISGKLRAQWEMGIVQAE---EAA 333

Query: 120 EGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEE 179
               +++  A+ +    G  +   P   K E G      G++ E S    + AENP+   
Sbjct: 334 SMSVEER-KAKFTFLYVGDQLHLNPQVAK-EAGIAAESLGEMAESSGVSEEAAENPKSVR 391

Query: 180 KEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEE 218
           +E   ++  R   +     +  S P  G+  PQ+  E +
Sbjct: 392 EECIPMKRRRRAKLCSSAETLESHPDIGKSTPQKTAEAD 430



 Score = 32.3 bits (72), Expect = 0.38
 Identities = 16/60 (26%), Positives = 28/60 (46%), Gaps = 5/60 (8%)

Query: 14  DLVFAKMKGYPHWPARIDEMPEAA-----VKSTANKYQVFFFGTHETAFLGPKDLFPYEE 68
           D+++ K+  Y  WPA +            +K    ++ VFFFG+ +  +     +FPY E
Sbjct: 882 DIIWVKLGNYRWWPAEVCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYME 941


>gi|6594683 Wolf-Hirschhorn syndrome candidate 1 protein isoform 4
           [Homo sapiens]
          Length = 629

 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 56/219 (25%), Positives = 94/219 (42%), Gaps = 16/219 (7%)

Query: 9   EYKCGDLVFAKMKGYPHWPARIDEMP-------EAAVKSTANKYQVFFFG-THETAFLGP 60
           +Y  GDLV++K+ GYP WP  +   P           K +A +Y V FFG   E A++  
Sbjct: 219 KYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFE 278

Query: 61  KDLFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVK-ASGYQSSQKKSCVEEPEPEPEAA 119
           K L  + E + +F K  +     +   + E    +K  SG   +Q +  + + E   EAA
Sbjct: 279 KSLVAF-EGEGQFEKLCQESA-KQAPTKAEKIKLLKPISGKLRAQWEMGIVQAE---EAA 333

Query: 120 EGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEE 179
               +++  A+ +    G  +   P   K E G      G++ E S    + AENP+   
Sbjct: 334 SMSVEER-KAKFTFLYVGDQLHLNPQVAK-EAGIAAESLGEMAESSGVSEEAAENPKSVR 391

Query: 180 KEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEE 218
           +E   ++  R   +     +  S P  G+  PQ+  E +
Sbjct: 392 EECIPMKRRRRAKLCSSAETLESHPDIGKSTPQKTAEAD 430


>gi|19913350 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
           [Homo sapiens]
          Length = 1365

 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 56/219 (25%), Positives = 94/219 (42%), Gaps = 16/219 (7%)

Query: 9   EYKCGDLVFAKMKGYPHWPARIDEMP-------EAAVKSTANKYQVFFFG-THETAFLGP 60
           +Y  GDLV++K+ GYP WP  +   P           K +A +Y V FFG   E A++  
Sbjct: 219 KYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFE 278

Query: 61  KDLFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVK-ASGYQSSQKKSCVEEPEPEPEAA 119
           K L  + E + +F K  +     +   + E    +K  SG   +Q +  + + E   EAA
Sbjct: 279 KSLVAF-EGEGQFEKLCQESA-KQAPTKAEKIKLLKPISGKLRAQWEMGIVQAE---EAA 333

Query: 120 EGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEE 179
               +++  A+ +    G  +   P   K E G      G++ E S    + AENP+   
Sbjct: 334 SMSVEER-KAKFTFLYVGDQLHLNPQVAK-EAGIAAESLGEMAESSGVSEEAAENPKSVR 391

Query: 180 KEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEE 218
           +E   ++  R   +     +  S P  G+  PQ+  E +
Sbjct: 392 EECIPMKRRRRAKLCSSAETLESHPDIGKSTPQKTAEAD 430



 Score = 32.3 bits (72), Expect = 0.38
 Identities = 16/60 (26%), Positives = 28/60 (46%), Gaps = 5/60 (8%)

Query: 14  DLVFAKMKGYPHWPARIDEMPEAA-----VKSTANKYQVFFFGTHETAFLGPKDLFPYEE 68
           D+++ K+  Y  WPA +            +K    ++ VFFFG+ +  +     +FPY E
Sbjct: 882 DIIWVKLGNYRWWPAEVCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYME 941


>gi|19913348 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
           [Homo sapiens]
          Length = 1365

 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 56/219 (25%), Positives = 94/219 (42%), Gaps = 16/219 (7%)

Query: 9   EYKCGDLVFAKMKGYPHWPARIDEMP-------EAAVKSTANKYQVFFFG-THETAFLGP 60
           +Y  GDLV++K+ GYP WP  +   P           K +A +Y V FFG   E A++  
Sbjct: 219 KYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFE 278

Query: 61  KDLFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVK-ASGYQSSQKKSCVEEPEPEPEAA 119
           K L  + E + +F K  +     +   + E    +K  SG   +Q +  + + E   EAA
Sbjct: 279 KSLVAF-EGEGQFEKLCQESA-KQAPTKAEKIKLLKPISGKLRAQWEMGIVQAE---EAA 333

Query: 120 EGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEE 179
               +++  A+ +    G  +   P   K E G      G++ E S    + AENP+   
Sbjct: 334 SMSVEER-KAKFTFLYVGDQLHLNPQVAK-EAGIAAESLGEMAESSGVSEEAAENPKSVR 391

Query: 180 KEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEE 218
           +E   ++  R   +     +  S P  G+  PQ+  E +
Sbjct: 392 EECIPMKRRRRAKLCSSAETLESHPDIGKSTPQKTAEAD 430



 Score = 32.3 bits (72), Expect = 0.38
 Identities = 16/60 (26%), Positives = 28/60 (46%), Gaps = 5/60 (8%)

Query: 14  DLVFAKMKGYPHWPARIDEMPEAA-----VKSTANKYQVFFFGTHETAFLGPKDLFPYEE 68
           D+++ K+  Y  WPA +            +K    ++ VFFFG+ +  +     +FPY E
Sbjct: 882 DIIWVKLGNYRWWPAEVCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYME 941


>gi|109633019 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
           [Homo sapiens]
          Length = 1365

 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 56/219 (25%), Positives = 94/219 (42%), Gaps = 16/219 (7%)

Query: 9   EYKCGDLVFAKMKGYPHWPARIDEMP-------EAAVKSTANKYQVFFFG-THETAFLGP 60
           +Y  GDLV++K+ GYP WP  +   P           K +A +Y V FFG   E A++  
Sbjct: 219 KYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFE 278

Query: 61  KDLFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVK-ASGYQSSQKKSCVEEPEPEPEAA 119
           K L  + E + +F K  +     +   + E    +K  SG   +Q +  + + E   EAA
Sbjct: 279 KSLVAF-EGEGQFEKLCQESA-KQAPTKAEKIKLLKPISGKLRAQWEMGIVQAE---EAA 333

Query: 120 EGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEE 179
               +++  A+ +    G  +   P   K E G      G++ E S    + AENP+   
Sbjct: 334 SMSVEER-KAKFTFLYVGDQLHLNPQVAK-EAGIAAESLGEMAESSGVSEEAAENPKSVR 391

Query: 180 KEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEE 218
           +E   ++  R   +     +  S P  G+  PQ+  E +
Sbjct: 392 EECIPMKRRRRAKLCSSAETLESHPDIGKSTPQKTAEAD 430



 Score = 32.3 bits (72), Expect = 0.38
 Identities = 16/60 (26%), Positives = 28/60 (46%), Gaps = 5/60 (8%)

Query: 14  DLVFAKMKGYPHWPARIDEMPEAA-----VKSTANKYQVFFFGTHETAFLGPKDLFPYEE 68
           D+++ K+  Y  WPA +            +K    ++ VFFFG+ +  +     +FPY E
Sbjct: 882 DIIWVKLGNYRWWPAEVCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYME 941


>gi|157738619 smoothelin-like 1 [Homo sapiens]
          Length = 512

 Score = 48.9 bits (115), Expect = 4e-06
 Identities = 53/230 (23%), Positives = 101/230 (43%), Gaps = 26/230 (11%)

Query: 2   SRSNRQKEYKCGDLVFAKMKGYPHW--PARIDEMPEAAVKSTANKYQVFFFGTHETAFLG 59
           + S +Q++    D + A+++G  +     +++   EA  K  A        G  E   +G
Sbjct: 66  TESGKQEKAPAEDGMSAELQGEANGLDEVKVESQREAGGKEDAEAELKKEDGEKEETTVG 125

Query: 60  PKDLFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAA 119
            +++   +E  E   +P + +     L   +     K +  +S QK    +  +PEP+A 
Sbjct: 126 SQEMTGRKE--ETKSEPKEAEEKESTLASEKQKAEEKEAKPESGQKADANDRDKPEPKAT 183

Query: 120 EGDGDKK-------GNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEA 172
             + D K       G  +  S E  +   DE AK +++K  ++       +++   PKE 
Sbjct: 184 VEEEDAKTASQEETGQRKECSTEPKEKATDEEAKAESQKAVVE-------DEAKAEPKE- 235

Query: 173 ENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEE 222
             P+G+E+     + E     E E ++  +EPGS    P EE+E++ E+E
Sbjct: 236 --PDGKEEAKHGAKEEADAKEEAE-DAEEAEPGS----PSEEQEQDVEKE 278



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 47/207 (22%), Positives = 78/207 (37%), Gaps = 29/207 (14%)

Query: 60  PKDLFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAA 119
           P +    E++  + G   + +G + GL E++     +A G + ++ +   E+ E E E  
Sbjct: 65  PTESGKQEKAPAEDGMSAELQGEANGLDEVKVESQREAGGKEDAEAELKKEDGEKE-ETT 123

Query: 120 EGDGDKKGNAEGSSDE-------EGKLVIDEPAKEKNE---KGALKRRAGDLLEDSPKRP 169
            G  +  G  E +  E       E  L  ++   E+ E   +   K  A D  +  PK  
Sbjct: 124 VGSQEMTGRKEETKSEPKEAEEKESTLASEKQKAEEKEAKPESGQKADANDRDKPEPKAT 183

Query: 170 KEAENPE-------GEEKEAATLEVERPLPMEV-----------EKNSTPSEPGSGRGPP 211
            E E+ +       G+ KE +T   E+    E            E  + P EP       
Sbjct: 184 VEEEDAKTASQEETGQRKECSTEPKEKATDEEAKAESQKAVVEDEAKAEPKEPDGKEEAK 243

Query: 212 QEEEEEEDEEEEATKEDAEAPGIRDHE 238
              +EE D +EEA   +   PG    E
Sbjct: 244 HGAKEEADAKEEAEDAEEAEPGSPSEE 270



 Score = 35.4 bits (80), Expect = 0.044
 Identities = 34/155 (21%), Positives = 63/155 (40%), Gaps = 10/155 (6%)

Query: 88  EIENNPTVKASGYQS---SQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEP 144
           E    P  KA+  ++   SQK    +E + EP+  +G  + K  A+  +D + +    E 
Sbjct: 202 ECSTEPKEKATDEEAKAESQKAVVEDEAKAEPKEPDGKEEAKHGAKEEADAKEEAEDAEE 261

Query: 145 AK-----EKNEKGALKRRAGD--LLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEK 197
           A+     E+ E+   K   G   ++  SP+   E+   EG       L  +     +   
Sbjct: 262 AEPGSPSEEQEQDVEKEPEGGAGVIPSSPEEWPESPTGEGHNLSTDGLGPDCVASGQTSP 321

Query: 198 NSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAP 232
           +++ S P      P E     +++E+A +    AP
Sbjct: 322 SASESSPSDVPQSPPESPSSGEKKEKAPERRVSAP 356


>gi|13540523 nucleosomal binding protein 1 [Homo sapiens]
          Length = 282

 Score = 48.5 bits (114), Expect = 5e-06
 Identities = 38/144 (26%), Positives = 62/144 (43%), Gaps = 20/144 (13%)

Query: 101 QSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKEK------------ 148
           +  QK+   ++ E + EA + D D+KG  +G  D+ G     E AKEK            
Sbjct: 127 EEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGN-EKGEDAKEKEDGKKGEDGKGN 185

Query: 149 ----NEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEP 204
                EKG  ++   D  E    +  E    +G++KE   ++V+     E E+     + 
Sbjct: 186 GEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKED---EKEREDGKEDE 242

Query: 205 GSGRGPPQEEEEEEDEEEEATKED 228
           G       +E+E+  EEEE  +ED
Sbjct: 243 GGNEEEAGKEKEDLKEEEEGKEED 266



 Score = 34.7 bits (78), Expect = 0.076
 Identities = 36/149 (24%), Positives = 61/149 (40%), Gaps = 29/149 (19%)

Query: 93  PTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKG 152
           P VK     SS+K       + + +  E + D    A   + +E   V++E   E  + G
Sbjct: 32  PEVKPKRTSSSRKM------KTKSDMMEENIDTSAQAVAETKQEA--VVEEDYNENAKNG 83

Query: 153 ALKRRAG-----DLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSG 207
             K         +++E   +  ++A    GE+KEA   EV         KN    +    
Sbjct: 84  EAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEV---------KNEEEDQ---- 130

Query: 208 RGPPQEEEEEEDEEEEATKEDAEAPGIRD 236
               ++EE++ +E+ EA KED +  G  D
Sbjct: 131 ---KEDEEDQNEEKGEAGKEDKDEKGEED 156



 Score = 33.1 bits (74), Expect = 0.22
 Identities = 26/84 (30%), Positives = 41/84 (48%), Gaps = 3/84 (3%)

Query: 67  EESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKK 126
           E+ KEK G+  K +   +   + + N   K  G +   K   V+E E E E  +G  D+ 
Sbjct: 187 EDGKEK-GEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKERE--DGKEDEG 243

Query: 127 GNAEGSSDEEGKLVIDEPAKEKNE 150
           GN E +  E+  L  +E  KE++E
Sbjct: 244 GNEEEAGKEKEDLKEEEEGKEEDE 267



 Score = 32.7 bits (73), Expect = 0.29
 Identities = 39/161 (24%), Positives = 66/161 (40%), Gaps = 16/161 (9%)

Query: 88  EIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGN--AEGSSDEEGKLVIDEPA 145
           E   N   K +   +S+K+    + E   +A E  G+KK    AE  ++EE +    E  
Sbjct: 78  ENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQ---KEDE 134

Query: 146 KEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPG 205
           +++NE+   K  AG   +D        E+  G EK     E E     E  K +      
Sbjct: 135 EDQNEE---KGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKE 191

Query: 206 SGRGPPQEEE--------EEEDEEEEATKEDAEAPGIRDHE 238
            G    +EE+        E ED +E+  K++ +   +++ E
Sbjct: 192 KGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDE 232



 Score = 30.8 bits (68), Expect = 1.1
 Identities = 23/90 (25%), Positives = 38/90 (42%), Gaps = 4/90 (4%)

Query: 96  KASGYQSSQKKSCVEEPEPEPEAAEG----DGDKKGNAEGSSDEEGKLVIDEPAKEKNEK 151
           K +G    +K    +E E   E  +G    DG +KG+ +   D + K    E    K ++
Sbjct: 183 KGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDE 242

Query: 152 GALKRRAGDLLEDSPKRPKEAENPEGEEKE 181
           G  +  AG   ED  +  +  E  E +E +
Sbjct: 243 GGNEEEAGKEKEDLKEEEEGKEEDEIKEDD 272


>gi|4759128 solute carrier family 24 (sodium/potassium/calcium
           exchanger), member 1 [Homo sapiens]
          Length = 1099

 Score = 47.8 bits (112), Expect = 9e-06
 Identities = 35/131 (26%), Positives = 61/131 (46%), Gaps = 3/131 (2%)

Query: 103 SQKKSCVEEPEPEPEAA-EGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDL 161
           ++ +S  E P  E E A EG+ ++K   E   + EG+       +E  ++   + +  + 
Sbjct: 748 AEAESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNE 807

Query: 162 LEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGR--GPPQEEEEEED 219
            ED  +   E    +G E E  + E+      E + +    E G G   G  +EEEEEE+
Sbjct: 808 GEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEE 867

Query: 220 EEEEATKEDAE 230
           E+EE  +E+ +
Sbjct: 868 EQEEEEEEEEQ 878



 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 50/183 (27%), Positives = 75/183 (40%), Gaps = 27/183 (14%)

Query: 59  GPKDLFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEA 118
           G +D+   E + E  G+  +  G  EG  E ++    +  G   ++ +   EE E E EA
Sbjct: 743 GQEDVAEAESTGEMPGEEGETAG--EGETEEKSGGETQPEGEGETETQGKGEECEDENEA 800

Query: 119 AEGDGDKKGNAEGSSD-EEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEG 177
            EG GD +G  EG    E+G++  +E   E  E  A         E   +    ++  + 
Sbjct: 801 -EGKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDS 859

Query: 178 EEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAPGIRDH 237
           EE+E    E E                       +EEEEEE EEEE  +E+ E  G  + 
Sbjct: 860 EEEEEEEEEQE-----------------------EEEEEEEQEEEEEEEEEEEEKGNEEP 896

Query: 238 ESL 240
            SL
Sbjct: 897 LSL 899


>gi|156104891 general transcription factor IIF, polypeptide 1, 74kDa
           [Homo sapiens]
          Length = 517

 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 44/163 (26%), Positives = 77/163 (47%), Gaps = 20/163 (12%)

Query: 67  EESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSS-QKKSCVEEPEPEPEAAEGDGDK 125
           EE KEK G+   RK     + ++E++  + +    +S ++   V + + +   A+G G K
Sbjct: 191 EEEKEKRGR---RKASELRIHDLEDDLEMSSDASDASGEEGGRVPKAKKKAPLAKG-GRK 246

Query: 126 KGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATL 185
           K   +GS DE         A E ++ G  + +  D + D     +E    E E K  A  
Sbjct: 247 KKKKKGSDDE---------AFEDSDDGDFEGQEVDYMSDGSSSSQE----EPESKAKAPQ 293

Query: 186 EVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKED 228
           + E P    V++ S  SE      PP+E++EEE+E++  T ++
Sbjct: 294 QEEGP--KGVDEQSDSSEESEEEKPPEEDKEEEEEKKAPTPQE 334



 Score = 38.9 bits (89), Expect = 0.004
 Identities = 39/150 (26%), Positives = 64/150 (42%), Gaps = 12/150 (8%)

Query: 75  KPNKRKGFSEGLWEIENNPTVKAS--GYQSSQKKSCVEEPEPEPEAAEGDGDKKG---NA 129
           K  K+KG  +  +E  ++   +     Y S    S  EEPE + +A + +   KG    +
Sbjct: 246 KKKKKKGSDDEAFEDSDDGDFEGQEVDYMSDGSSSSQEEPESKAKAPQQEEGPKGVDEQS 305

Query: 130 EGSSDEEGKLVIDEPAKEKNEKGA----LKRRAGDLLEDSPKRPKEAENPEGEEKEAATL 185
           + S + E +   +E  +E+ EK A     K+R  D  E+S     E  + + E   A  +
Sbjct: 306 DSSEESEEEKPPEEDKEEEEEKKAPTPQEKKRRKDSSEESDS--SEESDIDSEASSALFM 363

Query: 186 EVERPLPMEVEKNSTPSEPGSGR-GPPQEE 214
             ++  P    K S  S  G+ R G P  E
Sbjct: 364 AKKKTPPKRERKPSGGSSRGNSRPGTPSAE 393



 Score = 37.7 bits (86), Expect = 0.009
 Identities = 32/130 (24%), Positives = 55/130 (42%), Gaps = 18/130 (13%)

Query: 99  GYQSSQKKSCVEEPEPEPEAAEGDG---DKKGNAEGSSDEEGKLVIDEPAKEKNEKGALK 155
           G +  +KK   +E   + +  + +G   D   +   SS EE +     P +E+  KG + 
Sbjct: 244 GRKKKKKKGSDDEAFEDSDDGDFEGQEVDYMSDGSSSSQEEPESKAKAPQQEEGPKG-VD 302

Query: 156 RRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEE 215
            ++    E   ++P E +  E EEK+A       P P E ++    SE         +  
Sbjct: 303 EQSDSSEESEEEKPPEEDKEEEEEKKA-------PTPQEKKRRKDSSE-------ESDSS 348

Query: 216 EEEDEEEEAT 225
           EE D + EA+
Sbjct: 349 EESDIDSEAS 358



 Score = 37.4 bits (85), Expect = 0.012
 Identities = 40/175 (22%), Positives = 68/175 (38%), Gaps = 21/175 (12%)

Query: 67  EESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKK 126
           EE++E++ + NK       + +       +    +  +K+   +  E      E D +  
Sbjct: 158 EEAEEEWERRNKVLNHFSIMQQRRLKDQDQDEDEEEKEKRGRRKASELRIHDLEDDLEMS 217

Query: 127 GNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLE 186
            +A  +S EEG  V     K    KG  K+          K+ K +++   E+ +    E
Sbjct: 218 SDASDASGEEGGRVPKAKKKAPLAKGGRKK----------KKKKGSDDEAFEDSDDGDFE 267

Query: 187 VERPLPMEVEKNSTPSEPGSGRGPPQEEE-----------EEEDEEEEATKEDAE 230
            +    M    +S+  EP S    PQ+EE            EE EEE+  +ED E
Sbjct: 268 GQEVDYMSDGSSSSQEEPESKAKAPQQEEGPKGVDEQSDSSEESEEEKPPEEDKE 322


>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
          Length = 709

 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 47/183 (25%), Positives = 78/183 (42%), Gaps = 19/183 (10%)

Query: 61  KDLFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAE 120
           K    Y+  + +  + NKR        +I  + +     Y++  +K+CV + +PE  A  
Sbjct: 90  KSATEYKNEEYQRSERNKRLDADR---KIRLSSSASREPYKNQPEKTCVRKRDPERRA-- 144

Query: 121 GDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLED-----SPKRPKEAENP 175
               K    +GS  E   L +D  A   ++    +  + +   D     S    ++  N 
Sbjct: 145 ----KSPTPDGS--ERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNT 198

Query: 176 EGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAPGIR 235
           E EE E    +VE     EVE+++   E     G  +EEEEEE+EEEE  +E+      R
Sbjct: 199 ENEE-EGVEEDVEED--EEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDER 255

Query: 236 DHE 238
           D +
Sbjct: 256 DQK 258



 Score = 27.7 bits (60), Expect = 9.2
 Identities = 23/97 (23%), Positives = 40/97 (41%), Gaps = 9/97 (9%)

Query: 134 DEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPM 193
           +++ +L   E  ++KNEK   KR++  +     KR K    P    ++     V +PL  
Sbjct: 25  EQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQK----PSVHSRQL----VSKPLSS 76

Query: 194 EVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAE 230
            V  N        G+   + + EE    E   + DA+
Sbjct: 77  SVSNNKRIVST-KGKSATEYKNEEYQRSERNKRLDAD 112


>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
          Length = 727

 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 47/183 (25%), Positives = 78/183 (42%), Gaps = 19/183 (10%)

Query: 61  KDLFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAE 120
           K    Y+  + +  + NKR        +I  + +     Y++  +K+CV + +PE  A  
Sbjct: 90  KSATEYKNEEYQRSERNKRLDADR---KIRLSSSASREPYKNQPEKTCVRKRDPERRA-- 144

Query: 121 GDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLED-----SPKRPKEAENP 175
               K    +GS  E   L +D  A   ++    +  + +   D     S    ++  N 
Sbjct: 145 ----KSPTPDGS--ERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNT 198

Query: 176 EGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAPGIR 235
           E EE E    +VE     EVE+++   E     G  +EEEEEE+EEEE  +E+      R
Sbjct: 199 ENEE-EGVEEDVEED--EEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDER 255

Query: 236 DHE 238
           D +
Sbjct: 256 DQK 258



 Score = 27.7 bits (60), Expect = 9.2
 Identities = 23/97 (23%), Positives = 40/97 (41%), Gaps = 9/97 (9%)

Query: 134 DEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPM 193
           +++ +L   E  ++KNEK   KR++  +     KR K    P    ++     V +PL  
Sbjct: 25  EQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQK----PSVHSRQL----VSKPLSS 76

Query: 194 EVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAE 230
            V  N        G+   + + EE    E   + DA+
Sbjct: 77  SVSNNKRIVST-KGKSATEYKNEEYQRSERNKRLDAD 112


>gi|15721939 metastatic lymph node 51 [Homo sapiens]
          Length = 703

 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 37/130 (28%), Positives = 65/130 (50%), Gaps = 13/130 (10%)

Query: 95  VKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGAL 154
           V++ G +S+++  C  E   E +A   D +   +AE S  EEG     E ++E+N K  L
Sbjct: 64  VESGGAKSAEESECESEDGIEGDAVLSDYE---SAEDSEGEEG-----EYSEEENSKVEL 115

Query: 155 KRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEE 214
           K  A D +  S K  K  E P+ +    +T+  ER    + ++++ P E   G+  P+  
Sbjct: 116 KSEANDAVNSSTKEEKGEEKPDTK----STVTGERQ-SGDGQESTEPVENKVGKKGPKHL 170

Query: 215 EEEEDEEEEA 224
           +++ED +  A
Sbjct: 171 DDDEDRKNPA 180


>gi|13699811 WHSC1L1 protein isoform long [Homo sapiens]
          Length = 1437

 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 62/234 (26%), Positives = 97/234 (41%), Gaps = 39/234 (16%)

Query: 9   EYKCGDLVFAKMKGYPHWPARIDEMPEAAVKSTAN-----KYQVFFFGTH-ETAFLGPKD 62
           +++ GDLV++K+  YP WP  +   P+  V +  N     +Y V FF    E A++  K 
Sbjct: 267 KFQVGDLVWSKVGTYPWWPCMVSSDPQLEVHTKINTRGAREYHVQFFSNQPERAWVHEKR 326

Query: 63  LFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGD 122
           +  Y+  K+          + E L E     T +AS +   QK   + +P P+ E A+ D
Sbjct: 327 VREYKGHKQ----------YEELLAE----ATKQASNHSEKQK---IRKPRPQRERAQWD 369

Query: 123 -----GDK--KGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENP 175
                 +K  K   E   ++   + ID+  +E   + A K  A        +RP+   N 
Sbjct: 370 IGIAHAEKALKMTREERIEQYTFIYIDKQPEEALSQ-AKKSVASKTEVKKTRRPRSVLNT 428

Query: 176 EGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDA 229
           + E+  A   EV   L      +ST     S R     EEEE    + A K  A
Sbjct: 429 QPEQTNAG--EVASSL------SSTEIRRHSQRRHTSAEEEEPPPVKIAWKTAA 474



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 9/93 (9%)

Query: 3    RSNRQKEYKCGDLVFAKMKGYPHWPARIDEMPEA-----AVKSTANKYQVFFFGTHETAF 57
            ++ ++  YK   +V+ K+  Y  WPA I            +K     + VFFFG+H+  +
Sbjct: 953  KAGKKLHYK--QIVWVKLGNYRWWPAEICNPRSVPLNIQGLKHDLGDFPVFFFGSHDYYW 1010

Query: 58   LGPKDLFPYEESKEKF--GKPNKRKGFSEGLWE 88
            +    +FPY E  + F  G+ +  K F + L E
Sbjct: 1011 VHQGRVFPYVEGDKSFAEGQTSINKTFKKALEE 1043


>gi|13699813 WHSC1L1 protein isoform short [Homo sapiens]
          Length = 645

 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 62/234 (26%), Positives = 97/234 (41%), Gaps = 39/234 (16%)

Query: 9   EYKCGDLVFAKMKGYPHWPARIDEMPEAAVKSTAN-----KYQVFFFGTH-ETAFLGPKD 62
           +++ GDLV++K+  YP WP  +   P+  V +  N     +Y V FF    E A++  K 
Sbjct: 267 KFQVGDLVWSKVGTYPWWPCMVSSDPQLEVHTKINTRGAREYHVQFFSNQPERAWVHEKR 326

Query: 63  LFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGD 122
           +  Y+  K+          + E L E     T +AS +   QK   + +P P+ E A+ D
Sbjct: 327 VREYKGHKQ----------YEELLAE----ATKQASNHSEKQK---IRKPRPQRERAQWD 369

Query: 123 -----GDK--KGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENP 175
                 +K  K   E   ++   + ID+  +E   + A K  A        +RP+   N 
Sbjct: 370 IGIAHAEKALKMTREERIEQYTFIYIDKQPEEALSQ-AKKSVASKTEVKKTRRPRSVLNT 428

Query: 176 EGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDA 229
           + E+  A   EV   L      +ST     S R     EEEE    + A K  A
Sbjct: 429 QPEQTNAG--EVASSL------SSTEIRRHSQRRHTSAEEEEPPPVKIAWKTAA 474


>gi|21237808 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin c2 isoform b [Homo sapiens]
          Length = 1130

 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 34/121 (28%), Positives = 59/121 (48%), Gaps = 22/121 (18%)

Query: 115 EPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAEN 174
           EPE  E  G+ +   EG + +E K    EP + +   GA++  A +   ++PK+ +E   
Sbjct: 778 EPERIEESGNDEARVEGQATDEKK----EPKEPREGGGAIEEEAKEKTSEAPKKDEE--- 830

Query: 175 PEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAPGI 234
            +G+E ++             EK S  S+ G     P++E+E ++ +EE  KE  E+ G 
Sbjct: 831 -KGKEGDS-------------EKESEKSD-GDPIVDPEKEKEPKEGQEEVLKEVVESEGE 875

Query: 235 R 235
           R
Sbjct: 876 R 876



 Score = 31.6 bits (70), Expect = 0.64
 Identities = 21/76 (27%), Positives = 32/76 (42%), Gaps = 11/76 (14%)

Query: 164 DSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEE 223
           D P+R +E+ N E   +  AT           ++   P EP  G G  +EE +E+  E  
Sbjct: 777 DEPERIEESGNDEARVEGQAT-----------DEKKEPKEPREGGGAIEEEAKEKTSEAP 825

Query: 224 ATKEDAEAPGIRDHES 239
              E+    G  + ES
Sbjct: 826 KKDEEKGKEGDSEKES 841



 Score = 30.0 bits (66), Expect = 1.9
 Identities = 25/105 (23%), Positives = 42/105 (40%), Gaps = 15/105 (14%)

Query: 88  EIENNPTVKASGYQSSQKKS---------CVEEPEPEPEAAEGDGDKKGNAEGSSDEE-- 136
           E   N   +  G  + +KK           +EE   E  +     D++   EG S++E  
Sbjct: 783 EESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKESE 842

Query: 137 ---GKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGE 178
              G  ++D P KEK  K   +    +++E   +R  + E   GE
Sbjct: 843 KSDGDPIVD-PEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGE 886


>gi|21237805 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin c2 isoform a [Homo sapiens]
          Length = 1214

 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 34/121 (28%), Positives = 59/121 (48%), Gaps = 22/121 (18%)

Query: 115 EPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAEN 174
           EPE  E  G+ +   EG + +E K    EP + +   GA++  A +   ++PK+ +E   
Sbjct: 747 EPERIEESGNDEARVEGQATDEKK----EPKEPREGGGAIEEEAKEKTSEAPKKDEE--- 799

Query: 175 PEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAPGI 234
            +G+E ++             EK S  S+ G     P++E+E ++ +EE  KE  E+ G 
Sbjct: 800 -KGKEGDS-------------EKESEKSD-GDPIVDPEKEKEPKEGQEEVLKEVVESEGE 844

Query: 235 R 235
           R
Sbjct: 845 R 845



 Score = 31.6 bits (70), Expect = 0.64
 Identities = 21/76 (27%), Positives = 32/76 (42%), Gaps = 11/76 (14%)

Query: 164 DSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEE 223
           D P+R +E+ N E   +  AT           ++   P EP  G G  +EE +E+  E  
Sbjct: 746 DEPERIEESGNDEARVEGQAT-----------DEKKEPKEPREGGGAIEEEAKEKTSEAP 794

Query: 224 ATKEDAEAPGIRDHES 239
              E+    G  + ES
Sbjct: 795 KKDEEKGKEGDSEKES 810



 Score = 30.0 bits (66), Expect = 1.9
 Identities = 25/105 (23%), Positives = 42/105 (40%), Gaps = 15/105 (14%)

Query: 88  EIENNPTVKASGYQSSQKKS---------CVEEPEPEPEAAEGDGDKKGNAEGSSDEE-- 136
           E   N   +  G  + +KK           +EE   E  +     D++   EG S++E  
Sbjct: 752 EESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKESE 811

Query: 137 ---GKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGE 178
              G  ++D P KEK  K   +    +++E   +R  + E   GE
Sbjct: 812 KSDGDPIVD-PEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGE 855


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.302    0.126    0.357 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,087,677
Number of Sequences: 37866
Number of extensions: 720349
Number of successful extensions: 14145
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 547
Number of HSP's successfully gapped in prelim test: 676
Number of HSP's that attempted gapping in prelim test: 5605
Number of HSP's gapped (non-prelim): 4951
length of query: 240
length of database: 18,247,518
effective HSP length: 99
effective length of query: 141
effective length of database: 14,498,784
effective search space: 2044328544
effective search space used: 2044328544
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.7 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press