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Search of human proteins with 4758516
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4758516 hepatoma-derived growth factor isoform a [Homo
sapiens]
(240 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4758516 hepatoma-derived growth factor isoform a [Homo sapiens] 494 e-140
gi|186928819 hepatoma-derived growth factor isoform b [Homo sapi... 432 e-121
gi|186928821 hepatoma-derived growth factor isoform c [Homo sapi... 431 e-121
gi|110681712 hepatoma derived growth factor-like 1 [Homo sapiens] 249 2e-66
gi|7705320 hepatoma-derived growth factor, related protein 3 [Ho... 204 7e-53
gi|190014588 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo... 185 3e-47
gi|190014586 PC4 and SFRS1 interacting protein 1 isoform 1 [Homo... 185 3e-47
gi|19923653 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo ... 185 3e-47
gi|48255931 hepatoma-derived growth factor-related protein 2 iso... 167 6e-42
gi|14249158 hepatoma-derived growth factor-related protein 2 iso... 167 6e-42
gi|40556376 cytokine-like nuclear factor n-pac [Homo sapiens] 69 4e-12
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 64 1e-10
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 51 8e-07
gi|19913356 Wolf-Hirschhorn syndrome candidate 1 protein isoform... 51 1e-06
gi|19913358 Wolf-Hirschhorn syndrome candidate 1 protein isoform... 51 1e-06
gi|6594683 Wolf-Hirschhorn syndrome candidate 1 protein isoform ... 51 1e-06
gi|19913350 Wolf-Hirschhorn syndrome candidate 1 protein isoform... 51 1e-06
gi|19913348 Wolf-Hirschhorn syndrome candidate 1 protein isoform... 51 1e-06
gi|109633019 Wolf-Hirschhorn syndrome candidate 1 protein isofor... 51 1e-06
gi|157738619 smoothelin-like 1 [Homo sapiens] 49 4e-06
gi|13540523 nucleosomal binding protein 1 [Homo sapiens] 49 5e-06
gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex... 48 9e-06
gi|156104891 general transcription factor IIF, polypeptide 1, 74... 47 1e-05
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 47 1e-05
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 47 1e-05
gi|15721939 metastatic lymph node 51 [Homo sapiens] 47 2e-05
gi|13699811 WHSC1L1 protein isoform long [Homo sapiens] 46 3e-05
gi|13699813 WHSC1L1 protein isoform short [Homo sapiens] 46 3e-05
gi|21237808 SWI/SNF-related matrix-associated actin-dependent re... 45 4e-05
gi|21237805 SWI/SNF-related matrix-associated actin-dependent re... 45 4e-05
>gi|4758516 hepatoma-derived growth factor isoform a [Homo sapiens]
Length = 240
Score = 494 bits (1272), Expect = e-140
Identities = 240/240 (100%), Positives = 240/240 (100%)
Query: 1 MSRSNRQKEYKCGDLVFAKMKGYPHWPARIDEMPEAAVKSTANKYQVFFFGTHETAFLGP 60
MSRSNRQKEYKCGDLVFAKMKGYPHWPARIDEMPEAAVKSTANKYQVFFFGTHETAFLGP
Sbjct: 1 MSRSNRQKEYKCGDLVFAKMKGYPHWPARIDEMPEAAVKSTANKYQVFFFGTHETAFLGP 60
Query: 61 KDLFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAE 120
KDLFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAE
Sbjct: 61 KDLFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAE 120
Query: 121 GDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEK 180
GDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEK
Sbjct: 121 GDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEK 180
Query: 181 EAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAPGIRDHESL 240
EAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAPGIRDHESL
Sbjct: 181 EAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAPGIRDHESL 240
>gi|186928819 hepatoma-derived growth factor isoform b [Homo
sapiens]
Length = 256
Score = 432 bits (1111), Expect = e-121
Identities = 212/214 (99%), Positives = 212/214 (99%)
Query: 27 PARIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEKFGKPNKRKGFSEGL 86
P IDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEKFGKPNKRKGFSEGL
Sbjct: 43 PHTIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEKFGKPNKRKGFSEGL 102
Query: 87 WEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAK 146
WEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAK
Sbjct: 103 WEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAK 162
Query: 147 EKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGS 206
EKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGS
Sbjct: 163 EKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGS 222
Query: 207 GRGPPQEEEEEEDEEEEATKEDAEAPGIRDHESL 240
GRGPPQEEEEEEDEEEEATKEDAEAPGIRDHESL
Sbjct: 223 GRGPPQEEEEEEDEEEEATKEDAEAPGIRDHESL 256
>gi|186928821 hepatoma-derived growth factor isoform c [Homo
sapiens]
Length = 233
Score = 431 bits (1108), Expect = e-121
Identities = 212/213 (99%), Positives = 212/213 (99%)
Query: 28 ARIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEKFGKPNKRKGFSEGLW 87
A IDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEKFGKPNKRKGFSEGLW
Sbjct: 21 AVIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEKFGKPNKRKGFSEGLW 80
Query: 88 EIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKE 147
EIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKE
Sbjct: 81 EIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKE 140
Query: 148 KNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSG 207
KNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSG
Sbjct: 141 KNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSG 200
Query: 208 RGPPQEEEEEEDEEEEATKEDAEAPGIRDHESL 240
RGPPQEEEEEEDEEEEATKEDAEAPGIRDHESL
Sbjct: 201 RGPPQEEEEEEDEEEEATKEDAEAPGIRDHESL 233
>gi|110681712 hepatoma derived growth factor-like 1 [Homo sapiens]
Length = 251
Score = 249 bits (635), Expect = 2e-66
Identities = 141/251 (56%), Positives = 161/251 (64%), Gaps = 28/251 (11%)
Query: 10 YKCGDLVFAKMKGYPHWPARIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEES 69
YK GDLVFAK+KGY HWPARI+ M + N+YQVFFFGTHETAFL PK LFPY+E
Sbjct: 9 YKSGDLVFAKLKGYAHWPARIEHMTQP------NRYQVFFFGTHETAFLSPKRLFPYKEC 62
Query: 70 KEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNA 129
KEKFGKPNKR+GFS GLWEIENNPTV+AS + +K + P PEPEAAEGD DK +A
Sbjct: 63 KEKFGKPNKRRGFSAGLWEIENNPTVQASDCPLASEKGSGDGPWPEPEAAEGDEDKPTHA 122
Query: 130 EGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKE-------- 181
G DE GK D+P +E EKG LKR AGD ED+PKRPKEA + EE E
Sbjct: 123 GGGGDELGKPDDDKPTEE--EKGPLKRSAGDPPEDAPKRPKEAAPDQEEEAEAERAAEAE 180
Query: 182 -------AATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKE-----DA 229
A ++ E P + VE S PSEPG PPQ EEEE EEE A +E A
Sbjct: 181 RAAAAAAATAVDEESPFLVAVENGSAPSEPGLVCEPPQPEEEELREEEVADEEASQEWHA 240
Query: 230 EAPGIRDHESL 240
EAPG D +SL
Sbjct: 241 EAPGGGDRDSL 251
>gi|7705320 hepatoma-derived growth factor, related protein 3 [Homo
sapiens]
Length = 203
Score = 204 bits (518), Expect = 7e-53
Identities = 110/221 (49%), Positives = 138/221 (62%), Gaps = 23/221 (10%)
Query: 6 RQKEYKCGDLVFAKMKGYPHWPARIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFP 65
R +EYK GDLVFAKMKGYPHWPARIDE+PE AVK ANKY +FFFGTHETAFLGPKDLFP
Sbjct: 5 RPREYKAGDLVFAKMKGYPHWPARIDELPEGAVKPPANKYPIFFFGTHETAFLGPKDLFP 64
Query: 66 YEESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDK 125
Y+E K+KFGK NKRKGF+EGLWEIENNP VK +GYQ+ Q++S ++E +G+
Sbjct: 65 YKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQS----------SSETEGEG 114
Query: 126 KGNAEGSSDEEG-KLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAAT 184
A+ SS+EEG ++ D K KNEK KR+ S K K++ G+E +
Sbjct: 115 GNTADASSEEEGDRVEEDGKGKRKNEKAGSKRKKS---YTSKKSSKQSRKSPGDEDDKDC 171
Query: 185 LEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEAT 225
E E+N + SE G + + + E T
Sbjct: 172 KE---------EENKSSSEGGDAGNDTRNTTSDLQKTSEGT 203
>gi|190014588 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo
sapiens]
Length = 530
Score = 185 bits (469), Expect = 3e-47
Identities = 112/265 (42%), Positives = 154/265 (58%), Gaps = 41/265 (15%)
Query: 8 KEYKCGDLVFAKMKGYPHWPARIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYE 67
+++K GDL+FAKMKGYPHWPAR+DE+P+ AVK NK +FFFGTHETAFLGPKD+FPY
Sbjct: 3 RDFKPGDLIFAKMKGYPHWPARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPKDIFPYS 62
Query: 68 ESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKK----SCVEEPEPEPEAAEGDG 123
E+KEK+GKPNKRKGF+EGLWEI+NNP VK S Q++ K+ S VE E E ++ D
Sbjct: 63 ENKEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDT 122
Query: 124 DKKGNAEGSSDEEGKLVID--------EPAKEKNEKGALKRRAGDL--------LEDSPK 167
D + E +S+E+ +D K K EK AG + L+ SPK
Sbjct: 123 D---HEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPK 179
Query: 168 RPKEA------ENPEGEEKEAATLEVERPLPME----VEKNSTPSEPGSGRGP---PQEE 214
R + A P G K V++P P E E++ + + + P P+++
Sbjct: 180 RGRPAATEVKIPKPRGRPK-----MVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKD 234
Query: 215 EEEEDEEEEATKEDAEAPGIRDHES 239
EE + EE++ KE + G ++ ES
Sbjct: 235 EEGQKEEDKPRKEPDKKEGKKEVES 259
Score = 32.0 bits (71), Expect = 0.49
Identities = 26/116 (22%), Positives = 51/116 (43%), Gaps = 10/116 (8%)
Query: 67 EESKEKFGKPNKRKGFSEGLWEIEN-NPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDK 125
EE +++ KP K EG E+E+ + +G S+ + E E + EG+ +
Sbjct: 235 EEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGVTST------SDSEEEGDDQEGEKKR 288
Query: 126 KGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKE 181
KG + ++ + KE ++ KR+ + +E + E + PE ++ E
Sbjct: 289 KGGRNFQTAHRRNMLKGQHEKEAADR---KRKQEEQMETEQQNKDEGKKPEVKKVE 341
>gi|190014586 PC4 and SFRS1 interacting protein 1 isoform 1 [Homo
sapiens]
Length = 333
Score = 185 bits (469), Expect = 3e-47
Identities = 112/265 (42%), Positives = 154/265 (58%), Gaps = 41/265 (15%)
Query: 8 KEYKCGDLVFAKMKGYPHWPARIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYE 67
+++K GDL+FAKMKGYPHWPAR+DE+P+ AVK NK +FFFGTHETAFLGPKD+FPY
Sbjct: 3 RDFKPGDLIFAKMKGYPHWPARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPKDIFPYS 62
Query: 68 ESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKK----SCVEEPEPEPEAAEGDG 123
E+KEK+GKPNKRKGF+EGLWEI+NNP VK S Q++ K+ S VE E E ++ D
Sbjct: 63 ENKEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDT 122
Query: 124 DKKGNAEGSSDEEGKLVID--------EPAKEKNEKGALKRRAGDL--------LEDSPK 167
D + E +S+E+ +D K K EK AG + L+ SPK
Sbjct: 123 D---HEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPK 179
Query: 168 RPKEA------ENPEGEEKEAATLEVERPLPME----VEKNSTPSEPGSGRGP---PQEE 214
R + A P G K V++P P E E++ + + + P P+++
Sbjct: 180 RGRPAATEVKIPKPRGRPK-----MVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKD 234
Query: 215 EEEEDEEEEATKEDAEAPGIRDHES 239
EE + EE++ KE + G ++ ES
Sbjct: 235 EEGQKEEDKPRKEPDKKEGKKEVES 259
>gi|19923653 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo
sapiens]
Length = 530
Score = 185 bits (469), Expect = 3e-47
Identities = 112/265 (42%), Positives = 154/265 (58%), Gaps = 41/265 (15%)
Query: 8 KEYKCGDLVFAKMKGYPHWPARIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYE 67
+++K GDL+FAKMKGYPHWPAR+DE+P+ AVK NK +FFFGTHETAFLGPKD+FPY
Sbjct: 3 RDFKPGDLIFAKMKGYPHWPARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPKDIFPYS 62
Query: 68 ESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKK----SCVEEPEPEPEAAEGDG 123
E+KEK+GKPNKRKGF+EGLWEI+NNP VK S Q++ K+ S VE E E ++ D
Sbjct: 63 ENKEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDT 122
Query: 124 DKKGNAEGSSDEEGKLVID--------EPAKEKNEKGALKRRAGDL--------LEDSPK 167
D + E +S+E+ +D K K EK AG + L+ SPK
Sbjct: 123 D---HEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPK 179
Query: 168 RPKEA------ENPEGEEKEAATLEVERPLPME----VEKNSTPSEPGSGRGP---PQEE 214
R + A P G K V++P P E E++ + + + P P+++
Sbjct: 180 RGRPAATEVKIPKPRGRPK-----MVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKD 234
Query: 215 EEEEDEEEEATKEDAEAPGIRDHES 239
EE + EE++ KE + G ++ ES
Sbjct: 235 EEGQKEEDKPRKEPDKKEGKKEVES 259
Score = 32.0 bits (71), Expect = 0.49
Identities = 26/116 (22%), Positives = 51/116 (43%), Gaps = 10/116 (8%)
Query: 67 EESKEKFGKPNKRKGFSEGLWEIEN-NPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDK 125
EE +++ KP K EG E+E+ + +G S+ + E E + EG+ +
Sbjct: 235 EEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGVTST------SDSEEEGDDQEGEKKR 288
Query: 126 KGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKE 181
KG + ++ + KE ++ KR+ + +E + E + PE ++ E
Sbjct: 289 KGGRNFQTAHRRNMLKGQHEKEAADR---KRKQEEQMETEQQNKDEGKKPEVKKVE 341
>gi|48255931 hepatoma-derived growth factor-related protein 2
isoform 1 [Homo sapiens]
Length = 671
Score = 167 bits (424), Expect = 6e-42
Identities = 91/214 (42%), Positives = 124/214 (57%), Gaps = 16/214 (7%)
Query: 10 YKCGDLVFAKMKGYPHWPARIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEES 69
+K GDLVFAKMKGYPHWPARID++ + AVK NKY +FFFGTHETAFLGPKDLFPY++
Sbjct: 5 FKPGDLVFAKMKGYPHWPARIDDIADGAVKPPPNKYPIFFFGTHETAFLGPKDLFPYDKC 64
Query: 70 KEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEG-DGDKKGN 128
K+K+GKPNKRKGF+EGLWEI+NNP + Y + S + PE A+G D D+
Sbjct: 65 KDKYGKPNKRKGFNEGLWEIQNNP---HASYSAPPPVSSSDSEAPEANPADGSDADEDDE 121
Query: 129 AEG--------SSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEK 180
G ++ ++ D + + ++ LKR+ L KR ++A + +
Sbjct: 122 DRGVMAVTAVTATAASDRMESDSDSDKSSDNSGLKRKTPALKMSVSKRARKASSDLDQAS 181
Query: 181 EAATLEVERPLPMEVEKNS----TPSEPGSGRGP 210
+ + E E EK S TP + + R P
Sbjct: 182 VSPSEEENSESSSESEKTSDQDFTPEKKAAVRAP 215
Score = 38.1 bits (87), Expect = 0.007
Identities = 34/140 (24%), Positives = 56/140 (40%), Gaps = 13/140 (9%)
Query: 96 KASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALK 155
KA S K+ + +PEP A ++ SSD + + ++ EK K
Sbjct: 227 KAPSASDSDSKADSDGAKPEPVAMARSASSSSSSSSSSDSDVSVKKPPRGRKPAEKPLPK 286
Query: 156 RRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEE 215
R ++PK P ++ + EV+R + + E + R QEEE
Sbjct: 287 PRG--------RKPKPERPPSSSSSDSDSDEVDRISEWKRRDEARRRELEARRRREQEEE 338
Query: 216 -----EEEDEEEEATKEDAE 230
E+E EE+E +E A+
Sbjct: 339 LRRLREQEKEEKERRRERAD 358
Score = 35.4 bits (80), Expect = 0.044
Identities = 31/126 (24%), Positives = 51/126 (40%), Gaps = 6/126 (4%)
Query: 111 EPEPEPEAAEGDGDKKGN---AEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPK 167
+PE P ++ D D +E +E + E + + ++ L+R E+ +
Sbjct: 293 KPERPPSSSSSDSDSDEVDRISEWKRRDEARRRELEARRRREQEEELRRLREQEKEEKER 352
Query: 168 RPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEE-EDEEEEATK 226
R + A+ E E + E L + E G GRGPP + E E E E K
Sbjct: 353 RRERADRGEAERGSGGSSGDE--LREDDEPVKKRGRKGRGRGPPSSSDSEPEAELEREAK 410
Query: 227 EDAEAP 232
+ A+ P
Sbjct: 411 KSAKKP 416
Score = 35.0 bits (79), Expect = 0.058
Identities = 38/141 (26%), Positives = 60/141 (42%), Gaps = 27/141 (19%)
Query: 110 EEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKG---------------AL 154
EE E E A+ ++G+ S DE + DEP K++ KG L
Sbjct: 348 EEKERRRERADRGEAERGSGGSSGDELRE--DDEPVKKRGRKGRGRGPPSSSDSEPEAEL 405
Query: 155 KRRAGDLLEDSPKRPKE-----AENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRG 209
+R A + S K+P+ A P +EK E ++ P++VE+ SE G
Sbjct: 406 EREA----KKSAKKPQSSSTEPARKPGQKEKRVRPEEKQQAKPVKVERTRKRSE-GFSMD 460
Query: 210 PPQEEEEEEDEEEEATKEDAE 230
E+++E EE+ K +E
Sbjct: 461 RKVEKKKEPSVEEKLQKLHSE 481
Score = 32.0 bits (71), Expect = 0.49
Identities = 24/98 (24%), Positives = 38/98 (38%), Gaps = 16/98 (16%)
Query: 143 EPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPS 202
E ++ N+ G K +A + L +EA + E+K + L S
Sbjct: 556 EAVQKVNKAGMEKEKAEEKLAGEELAGEEAPQEKAEDKPSTDL----------------S 599
Query: 203 EPGSGRGPPQEEEEEEDEEEEATKEDAEAPGIRDHESL 240
P +G Q+ E ED+E E ++ E P E L
Sbjct: 600 APVNGEATSQKGESAEDKEHEEGRDSEEGPRCGSSEDL 637
>gi|14249158 hepatoma-derived growth factor-related protein 2
isoform 2 [Homo sapiens]
Length = 670
Score = 167 bits (424), Expect = 6e-42
Identities = 91/214 (42%), Positives = 124/214 (57%), Gaps = 16/214 (7%)
Query: 10 YKCGDLVFAKMKGYPHWPARIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEES 69
+K GDLVFAKMKGYPHWPARID++ + AVK NKY +FFFGTHETAFLGPKDLFPY++
Sbjct: 5 FKPGDLVFAKMKGYPHWPARIDDIADGAVKPPPNKYPIFFFGTHETAFLGPKDLFPYDKC 64
Query: 70 KEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEG-DGDKKGN 128
K+K+GKPNKRKGF+EGLWEI+NNP + Y + S + PE A+G D D+
Sbjct: 65 KDKYGKPNKRKGFNEGLWEIQNNP---HASYSAPPPVSSSDSEAPEANPADGSDADEDDE 121
Query: 129 AEG--------SSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEK 180
G ++ ++ D + + ++ LKR+ L KR ++A + +
Sbjct: 122 DRGVMAVTAVTATAASDRMESDSDSDKSSDNSGLKRKTPALKMSVSKRARKASSDLDQAS 181
Query: 181 EAATLEVERPLPMEVEKNS----TPSEPGSGRGP 210
+ + E E EK S TP + + R P
Sbjct: 182 VSPSEEENSESSSESEKTSDQDFTPEKKAAVRAP 215
Score = 38.1 bits (87), Expect = 0.007
Identities = 34/140 (24%), Positives = 56/140 (40%), Gaps = 13/140 (9%)
Query: 96 KASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALK 155
KA S K+ + +PEP A ++ SSD + + ++ EK K
Sbjct: 227 KAPSASDSDSKADSDGAKPEPVAMARSASSSSSSSSSSDSDVSVKKPPRGRKPAEKPLPK 286
Query: 156 RRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEE 215
R ++PK P ++ + EV+R + + E + R QEEE
Sbjct: 287 PRG--------RKPKPERPPSSSSSDSDSDEVDRISEWKRRDEARRRELEARRRREQEEE 338
Query: 216 -----EEEDEEEEATKEDAE 230
E+E EE+E +E A+
Sbjct: 339 LRRLREQEKEEKERRRERAD 358
Score = 35.4 bits (80), Expect = 0.044
Identities = 31/126 (24%), Positives = 51/126 (40%), Gaps = 6/126 (4%)
Query: 111 EPEPEPEAAEGDGDKKGN---AEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPK 167
+PE P ++ D D +E +E + E + + ++ L+R E+ +
Sbjct: 293 KPERPPSSSSSDSDSDEVDRISEWKRRDEARRRELEARRRREQEEELRRLREQEKEEKER 352
Query: 168 RPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEE-EDEEEEATK 226
R + A+ E E + E L + E G GRGPP + E E E E K
Sbjct: 353 RRERADRGEAERGSGGSSGDE--LREDDEPVKKRGRKGRGRGPPSSSDSEPEAELEREAK 410
Query: 227 EDAEAP 232
+ A+ P
Sbjct: 411 KSAKKP 416
Score = 35.0 bits (79), Expect = 0.058
Identities = 38/141 (26%), Positives = 60/141 (42%), Gaps = 27/141 (19%)
Query: 110 EEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKG---------------AL 154
EE E E A+ ++G+ S DE + DEP K++ KG L
Sbjct: 348 EEKERRRERADRGEAERGSGGSSGDELRE--DDEPVKKRGRKGRGRGPPSSSDSEPEAEL 405
Query: 155 KRRAGDLLEDSPKRPKE-----AENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRG 209
+R A + S K+P+ A P +EK E ++ P++VE+ SE G
Sbjct: 406 EREA----KKSAKKPQSSSTEPARKPGQKEKRVRPEEKQQAKPVKVERTRKRSE-GFSMD 460
Query: 210 PPQEEEEEEDEEEEATKEDAE 230
E+++E EE+ K +E
Sbjct: 461 RKVEKKKEPSVEEKLQKLHSE 481
Score = 32.0 bits (71), Expect = 0.49
Identities = 24/98 (24%), Positives = 38/98 (38%), Gaps = 16/98 (16%)
Query: 143 EPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPS 202
E ++ N+ G K +A + L +EA + E+K + L S
Sbjct: 556 EAVQKVNKAGMEKEKAEEKLAGEELAGEEAPQEKAEDKPSTDL----------------S 599
Query: 203 EPGSGRGPPQEEEEEEDEEEEATKEDAEAPGIRDHESL 240
P +G Q+ E ED+E E ++ E P E L
Sbjct: 600 APVNGEATSQKGESAEDKEHEEGRDSEEGPRCGSSEDL 637
Score = 28.1 bits (61), Expect = 7.1
Identities = 38/157 (24%), Positives = 58/157 (36%), Gaps = 25/157 (15%)
Query: 16 VFAKMKGYPHWPARIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEKFGK 75
V A +K + A D M +AA T K +V LGPK + +K K
Sbjct: 519 VVATLKKIRRYKANKDVMEKAAEVYTRLKSRV----------LGPKIEAVQKVNKAGMEK 568
Query: 76 PNKRKGFSEGLWEIENNPTVKA------------SGYQSSQKKSCVEEPEPEPEAAEGDG 123
+ + E P KA +G +SQK E+ E E +G
Sbjct: 569 EKAEEKLAGEELAGEEAPQEKAEDKPSTDLSAPVNGEATSQKGESAEDKEHEEGRDSEEG 628
Query: 124 DKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGD 160
+ G++E D +D P ++ E+ +R GD
Sbjct: 629 PRCGSSEDLHDVREGPDLDRPGSDRQER---ERARGD 662
>gi|40556376 cytokine-like nuclear factor n-pac [Homo sapiens]
Length = 553
Score = 68.9 bits (167), Expect = 4e-12
Identities = 64/215 (29%), Positives = 94/215 (43%), Gaps = 21/215 (9%)
Query: 11 KCGDLVFAKMKGYPHWPARIDEMPEAAVKSTANK-YQVFFFGTHETAFLGPKDLFPYEES 69
+ GDLV+ K+ YP WP +I P+ K K + V FFGT + A++ + L PY
Sbjct: 7 RLGDLVWGKLGRYPPWPGKIVNPPKDLKKPRGKKCFFVKFFGTEDHAWIKVEQLKPYHAH 66
Query: 70 KEKFGKPNKRKGFSEGLWEIEN-----NPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGD 124
KE+ K NK K F + + +E + S + SS K+ E GD
Sbjct: 67 KEEMIKINKGKRFQQAVDAVEEFLRRAKGKDQTSSHNSSDDKNRRNSSEERSRPNSGDEK 126
Query: 125 KK-GNAEGSSDE---EGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEE- 179
+K +EG + EGK + + E+ K LKR E SP+ K P+ E+
Sbjct: 127 RKLSLSEGKVKKNMGEGKKRVSSGSSERGSKSPLKRAQ----EQSPR--KRGRPPKDEKD 180
Query: 180 ---KEAATLEVERPLPMEVEK-NSTPSEPGSGRGP 210
E++T++ PM K T SEP P
Sbjct: 181 LTIPESSTVKGMMAGPMAAFKWQPTASEPVKDADP 215
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 63.9 bits (154), Expect = 1e-10
Identities = 64/213 (30%), Positives = 90/213 (42%), Gaps = 29/213 (13%)
Query: 22 GYPHWPARIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEKFGKPNKRKG 81
G HW DE E K G E G K+L EE K++ G+ ++K
Sbjct: 665 GAEHWQ---DEEREKGEKDKGR-------GEMERPGEGEKELAEKEEWKKRDGEEQEQKE 714
Query: 82 FSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVI 141
+G + E N ++ G EE E E EGD +++ EG EEG+
Sbjct: 715 REQG-HQKERNQEMEEGG----------EEEHGEGEEEEGDREEEEEKEGEGKEEGE--- 760
Query: 142 DEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTP 201
E + + EK +R+ + K +E + EGEE+E E+ EVE
Sbjct: 761 GEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVE----G 816
Query: 202 SEPGSGRGPPQEEEEE-EDEEEEATKEDAEAPG 233
E G+G +EEEEE E EEEE E+ E G
Sbjct: 817 GEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEG 849
Score = 56.6 bits (135), Expect = 2e-08
Identities = 52/173 (30%), Positives = 78/173 (45%), Gaps = 15/173 (8%)
Query: 67 EESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKK 126
EE +E G+ +G EG E G +++ E E E E EG+G+++
Sbjct: 860 EEGEEGEGEEEGEEGEGEGEEE---------EGEGEGEEEG---EGEGEEEEGEGEGEEE 907
Query: 127 GNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLE 186
G EG +EEG+ +E +E +G + G+ + + +E EGEE+E E
Sbjct: 908 GEGEGE-EEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEG-E 965
Query: 187 VERPLPMEVEKNSTPSEPGSGRGPPQEEE-EEEDEEEEATKEDAEAPGIRDHE 238
E E E+ E G G +EEE EEE EEE +E+ E G + E
Sbjct: 966 GEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEE 1018
Score = 49.3 bits (116), Expect = 3e-06
Identities = 45/166 (27%), Positives = 71/166 (42%), Gaps = 11/166 (6%)
Query: 68 ESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKG 127
E +E GK + EG E E G +++ E E E E EG+G+++G
Sbjct: 913 EEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEE--GEWEGEEEEGEGEGEEEG 970
Query: 128 NAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEV 187
EG EEG + +E+ +G + G+ E+ + + E EGE +E EV
Sbjct: 971 EGEG---EEG----EGEGEEEEGEGEGEEEEGE--EEGEEEGEGEEEGEGEGEEEEEGEV 1021
Query: 188 ERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAPG 233
E + E + E G G +E+E E +E +E+ E G
Sbjct: 1022 EGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEG 1067
Score = 48.5 bits (114), Expect = 5e-06
Identities = 52/171 (30%), Positives = 75/171 (43%), Gaps = 15/171 (8%)
Query: 67 EESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKK 126
EE + G+ + +G E E E V+ + + + EE E E E EG+G+++
Sbjct: 789 EEGDQGEGEEEETEGRGE---EKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEE 845
Query: 127 GNAEGSSDE-EGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATL 185
EG +E EGK + E E+G G+ E + +E E EGEE+E
Sbjct: 846 -EGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEG-EGEEEEGEG- 902
Query: 186 EVERPLPMEVEKNSTPSEPGSGRGPPQEEE---EEEDEEEEATKEDAEAPG 233
E E E + E G G+G + EE E E+EE E ED E G
Sbjct: 903 EGE-----EEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEG 948
Score = 47.0 bits (110), Expect = 1e-05
Identities = 55/191 (28%), Positives = 79/191 (41%), Gaps = 31/191 (16%)
Query: 67 EESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGD-- 124
EE +E G+ + +G EG E E G + + EE E E E EG+G
Sbjct: 869 EEGEEGEGEGEEEEGEGEGEEEGEGE------GEEEEGEGEGEEEGEGEGEEEEGEGKGE 922
Query: 125 ---KKGNAEGSSDE---EGKLVIDEPAKEKNE-KGALKRRAGDLLEDSPKRPKEAENPEG 177
++G EG +E EG+ E +E+ E +G + G+ E+ +E E EG
Sbjct: 923 EEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEG-EG 981
Query: 178 EEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEE--------------EEDE-EE 222
EE+E E E E+ E G G G +EE E EE+E EE
Sbjct: 982 EEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEE 1041
Query: 223 EATKEDAEAPG 233
E + + E G
Sbjct: 1042 EGEEREKEGEG 1052
Score = 45.1 bits (105), Expect = 6e-05
Identities = 49/174 (28%), Positives = 73/174 (41%), Gaps = 19/174 (10%)
Query: 67 EESKEKFG-KPNKRKGFSEGLWEIE-NNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGD 124
E +EK G + +K G E E+E N VK G + + + ++ + E +EG
Sbjct: 585 EIPEEKEGAEDSKGNGIEEQ--EVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGKAK 642
Query: 125 KKGNAEGSSD-------EEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEG 177
G AE + EEG + E+ EKG + G++ + AE E
Sbjct: 643 SVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEW 702
Query: 178 EEKEAATLEV-ERPLPMEVEKNSTPSEPGS---GRGPPQEEEEEEDEEEEATKE 227
++++ E ER + E+N E G G G EEEE D EEE KE
Sbjct: 703 KKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEG----EEEEGDREEEEEKE 752
Score = 45.1 bits (105), Expect = 6e-05
Identities = 46/166 (27%), Positives = 71/166 (42%), Gaps = 23/166 (13%)
Query: 67 EESKEKFGKPNKRKGFSE-GLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDK 125
EE E G+ + +G E G WE E + G + + + E E E E EG+G++
Sbjct: 934 EEEGEGEGEDGEGEGEEEEGEWEGEEEEG-EGEGEEEGEGEGEEGEGEGEEEEGEGEGEE 992
Query: 126 K-GNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAAT 184
+ G EG + EG+ E E+ E+G ++ + + E E EGEE
Sbjct: 993 EEGEEEGEEEGEGE-EEGEGEGEEEEEGEVEGEV-----EGEEGEGEGEEEEGEE----- 1041
Query: 185 LEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAE 230
E E+ E R +EEEEEE + +E +E+ E
Sbjct: 1042 ---------EGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENE 1078
Score = 36.6 bits (83), Expect = 0.020
Identities = 36/133 (27%), Positives = 60/133 (45%), Gaps = 6/133 (4%)
Query: 67 EESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKK 126
E E+ G+ +G EG E E + G + ++ EE E E E EG+G+++
Sbjct: 963 EGEGEEEGEGEGEEGEGEG--EEEEG---EGEGEEEEGEEEGEEEGEGEEEG-EGEGEEE 1016
Query: 127 GNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLE 186
E + EG+ E +E+ E+ +R E++ + +E E EG+ +E E
Sbjct: 1017 EEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEE 1076
Query: 187 VERPLPMEVEKNS 199
ER E +K S
Sbjct: 1077 NERQDGEEYKKVS 1089
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 51.2 bits (121), Expect = 8e-07
Identities = 49/179 (27%), Positives = 83/179 (46%), Gaps = 15/179 (8%)
Query: 68 ESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGD--- 124
+S EK P K + S E +P VK + KS V+E PE A+
Sbjct: 703 KSPEKAKSPVKEEAKSP---EKAKSP-VKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKT 758
Query: 125 ---KKGNAEGSSDEEGKLVIDE-PAKEKN---EKGALKRRAGDLLEDSPKRPKEAENPEG 177
K A+ + EE + D+ P K K+ E+ +A L++ K P E E P+
Sbjct: 759 LDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAP-EKEIPKK 817
Query: 178 EEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAPGIRD 236
EE ++ E E+P ++V++ +E P+ EE+++ ++EEA K++A P + +
Sbjct: 818 EEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEE 876
Score = 49.7 bits (117), Expect = 2e-06
Identities = 44/188 (23%), Positives = 82/188 (43%), Gaps = 22/188 (11%)
Query: 67 EESKEKFGKPNK--RKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDG- 123
+E+KE+ GK + + +EG E +P + + + KS V+E P A+
Sbjct: 476 KEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEK 535
Query: 124 -DKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKR-------------RAGDLLEDSPKRP 169
+ K AE S E+ K E AK E + ++ +A ++ K P
Sbjct: 536 EEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSP 595
Query: 170 KEAENPEG-----EEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEA 224
EA++PE +E+ + E + P+ E + + P + P +EE + ++ +
Sbjct: 596 AEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSP 655
Query: 225 TKEDAEAP 232
KE+A++P
Sbjct: 656 EKEEAKSP 663
Score = 48.5 bits (114), Expect = 5e-06
Identities = 39/138 (28%), Positives = 62/138 (44%), Gaps = 7/138 (5%)
Query: 101 QSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGD 160
+S +K VE+ E E E ++ E ++EE K +E KE+ E G + G
Sbjct: 439 KSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEE-EGGEEEEAEGG 497
Query: 161 LLEDSPKRPKEAENPEGEEKEAATLEVERPLPM---EVEKNSTPSE---PGSGRGPPQEE 214
E +EA +PE E K E + P E E+ +P+E P + P +EE
Sbjct: 498 EEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEE 557
Query: 215 EEEEDEEEEATKEDAEAP 232
+ E + KE+A++P
Sbjct: 558 AKSPPEAKSPEKEEAKSP 575
Score = 46.2 bits (108), Expect = 3e-05
Identities = 40/135 (29%), Positives = 64/135 (47%), Gaps = 20/135 (14%)
Query: 110 EEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAK-EKNEKGALKRRAGDLLEDSPKR 168
E+ E E E +G ++ AEG +E +E A EK K +K A K
Sbjct: 475 EKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEA--------KS 526
Query: 169 PKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQ----EEEEEEDEEEEA 224
P EA++PE EE ++ EV+ P EK +P++ + PP+ E+EE + E
Sbjct: 527 PAEAKSPEKEEAKSPA-EVKSP-----EKAKSPAKE-EAKSPPEAKSPEKEEAKSPAEVK 579
Query: 225 TKEDAEAPGIRDHES 239
+ E A++P + +S
Sbjct: 580 SPEKAKSPAKEEAKS 594
Score = 45.8 bits (107), Expect = 3e-05
Identities = 48/200 (24%), Positives = 78/200 (39%), Gaps = 36/200 (18%)
Query: 67 EESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKK 126
EE+K + K S E ++ P K+ + + KS E PE + + K
Sbjct: 536 EEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSP--EKEEAKSPAEVKSPEKAKSPAKEEAK 593
Query: 127 GNAEGSSDEEGKLVIDEPAKEKNE-KGALKRRAGDLLE------------DSPKRPKEAE 173
AE S E+ K + E AK E K +K A E + K P++A+
Sbjct: 594 SPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAK 653
Query: 174 NPEGEE-----KEAATLEVERPLPMEV-----------EKNSTP-----SEPGSGRGPPQ 212
+PE EE K + ++ E P + EK +P P + P +
Sbjct: 654 SPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVK 713
Query: 213 EEEEEEDEEEEATKEDAEAP 232
EE + ++ + KE+A+ P
Sbjct: 714 EEAKSPEKAKSPVKEEAKTP 733
Score = 40.8 bits (94), Expect = 0.001
Identities = 41/176 (23%), Positives = 72/176 (40%), Gaps = 18/176 (10%)
Query: 68 ESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKG 127
+S EK P K + S E KA + KS E P E A+ + K
Sbjct: 579 KSPEKAKSPAKEEAKSPA----EAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKS 634
Query: 128 NAEGSSDEEGKLVIDEPAKE-KNEKGALKRRAGDLLEDSPKRPKEAENP-----EGEEKE 181
+ S + + E AK + E+ +A ++ K P++A++P + EK
Sbjct: 635 PEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKA 694
Query: 182 AATLEVERPLPMEVEKNSTP-----SEPGSGRGPPQEEEEEEDEEEEATKEDAEAP 232
+ ++ E P EK +P P + P +EE + ++ + KE+A++P
Sbjct: 695 KSPVKEEAKSP---EKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSP 747
Score = 39.3 bits (90), Expect = 0.003
Identities = 48/212 (22%), Positives = 81/212 (38%), Gaps = 47/212 (22%)
Query: 68 ESKEKFGKPNKRKGFS--EGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDK 125
+S EK P K + S E ++ A + KS +E PE A+ +
Sbjct: 599 KSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKE 658
Query: 126 KG------------------------NAEGSSDEEGKLVIDEPAKEK-------NEKGAL 154
+ AE S E+ K + E AK E+
Sbjct: 659 EAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKS 718
Query: 155 KRRAGDLLEDSPKRPKEAENPEGEE----------KEAATLEVERP---LPMEVEKNSTP 201
+A +++ K P++A++P EE ++A TL+V+ P P + E S
Sbjct: 719 PEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPA 778
Query: 202 SE-PGSGRGPPQEEEEEEDEEEEATKEDAEAP 232
+ P + P +EE + ++ + KEDA+AP
Sbjct: 779 DKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAP 810
Score = 37.7 bits (86), Expect = 0.009
Identities = 49/216 (22%), Positives = 86/216 (39%), Gaps = 17/216 (7%)
Query: 28 ARIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEE---SKEKFGKPNKRKGFSE 84
A+ E ++ VK A + E A K P +E S EK P K K
Sbjct: 702 AKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDV 761
Query: 85 GLWEIENNPTVKASGYQSS---QKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVI 141
E + +A + KS V+E PE A+ + A + K +
Sbjct: 762 KSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAP-EKEIPKKEEV 820
Query: 142 DEPAKEKNEKGALK-----RRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVE 196
P KE+ + +K ++A + E +P PK E + +++EA E +P +VE
Sbjct: 821 KSPVKEEEKPQEVKVKEPPKKAEE--EKAPATPKTEEKKDSKKEEAPKKEAPKP---KVE 875
Query: 197 KNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAP 232
+ P+ + ++EE +++++ + EAP
Sbjct: 876 EKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAP 911
Score = 34.3 bits (77), Expect = 0.099
Identities = 31/142 (21%), Positives = 65/142 (45%), Gaps = 13/142 (9%)
Query: 101 QSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGD 160
++ +KK +E P+ EA + ++K +E K+ + K E+ K++
Sbjct: 852 KTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKV------EAKKEEAEDKKKVPT 905
Query: 161 LLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGR--GPPQEEEEEE 218
+++P + + E+ + +EK EV + P + K PS+P + P +++ +EE
Sbjct: 906 PEKEAPAKVEVKEDAKPKEK----TEVAKKEPDDA-KAKEPSKPAEKKEAAPEKKDTKEE 960
Query: 219 DEEEEATKEDAEAPGIRDHESL 240
++ K EA D ++L
Sbjct: 961 KAKKPEEKPKTEAKAKEDDKTL 982
Score = 28.9 bits (63), Expect = 4.2
Identities = 17/76 (22%), Positives = 31/76 (40%)
Query: 103 SQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLL 162
++KK E + E ++K E + E+ K + EP+K K EK
Sbjct: 945 AEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKD 1004
Query: 163 EDSPKRPKEAENPEGE 178
P++ E + +G+
Sbjct: 1005 SKPPEKATEDKAAKGK 1020
Score = 28.5 bits (62), Expect = 5.4
Identities = 23/77 (29%), Positives = 34/77 (44%), Gaps = 7/77 (9%)
Query: 163 EDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEE 222
E + + KEA+ EG+E+E E E E E S P+E + E+E + +
Sbjct: 469 EVTEEEEKEAKEEEGKEEEGG--EEEEAEGGEEETKSPPAEEAAS-----PEKEAKSPVK 521
Query: 223 EATKEDAEAPGIRDHES 239
E K AEA E+
Sbjct: 522 EEAKSPAEAKSPEKEEA 538
>gi|19913356 Wolf-Hirschhorn syndrome candidate 1 protein isoform 3
[Homo sapiens]
Length = 647
Score = 50.8 bits (120), Expect = 1e-06
Identities = 56/219 (25%), Positives = 94/219 (42%), Gaps = 16/219 (7%)
Query: 9 EYKCGDLVFAKMKGYPHWPARIDEMP-------EAAVKSTANKYQVFFFG-THETAFLGP 60
+Y GDLV++K+ GYP WP + P K +A +Y V FFG E A++
Sbjct: 219 KYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFE 278
Query: 61 KDLFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVK-ASGYQSSQKKSCVEEPEPEPEAA 119
K L + E + +F K + + + E +K SG +Q + + + E EAA
Sbjct: 279 KSLVAF-EGEGQFEKLCQESA-KQAPTKAEKIKLLKPISGKLRAQWEMGIVQAE---EAA 333
Query: 120 EGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEE 179
+++ A+ + G + P K E G G++ E S + AENP+
Sbjct: 334 SMSVEER-KAKFTFLYVGDQLHLNPQVAK-EAGIAAESLGEMAESSGVSEEAAENPKSVR 391
Query: 180 KEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEE 218
+E ++ R + + S P G+ PQ+ E +
Sbjct: 392 EECIPMKRRRRAKLCSSAETLESHPDIGKSTPQKTAEAD 430
>gi|19913358 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 50.8 bits (120), Expect = 1e-06
Identities = 56/219 (25%), Positives = 94/219 (42%), Gaps = 16/219 (7%)
Query: 9 EYKCGDLVFAKMKGYPHWPARIDEMP-------EAAVKSTANKYQVFFFG-THETAFLGP 60
+Y GDLV++K+ GYP WP + P K +A +Y V FFG E A++
Sbjct: 219 KYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFE 278
Query: 61 KDLFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVK-ASGYQSSQKKSCVEEPEPEPEAA 119
K L + E + +F K + + + E +K SG +Q + + + E EAA
Sbjct: 279 KSLVAF-EGEGQFEKLCQESA-KQAPTKAEKIKLLKPISGKLRAQWEMGIVQAE---EAA 333
Query: 120 EGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEE 179
+++ A+ + G + P K E G G++ E S + AENP+
Sbjct: 334 SMSVEER-KAKFTFLYVGDQLHLNPQVAK-EAGIAAESLGEMAESSGVSEEAAENPKSVR 391
Query: 180 KEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEE 218
+E ++ R + + S P G+ PQ+ E +
Sbjct: 392 EECIPMKRRRRAKLCSSAETLESHPDIGKSTPQKTAEAD 430
Score = 32.3 bits (72), Expect = 0.38
Identities = 16/60 (26%), Positives = 28/60 (46%), Gaps = 5/60 (8%)
Query: 14 DLVFAKMKGYPHWPARIDEMPEAA-----VKSTANKYQVFFFGTHETAFLGPKDLFPYEE 68
D+++ K+ Y WPA + +K ++ VFFFG+ + + +FPY E
Sbjct: 882 DIIWVKLGNYRWWPAEVCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYME 941
>gi|6594683 Wolf-Hirschhorn syndrome candidate 1 protein isoform 4
[Homo sapiens]
Length = 629
Score = 50.8 bits (120), Expect = 1e-06
Identities = 56/219 (25%), Positives = 94/219 (42%), Gaps = 16/219 (7%)
Query: 9 EYKCGDLVFAKMKGYPHWPARIDEMP-------EAAVKSTANKYQVFFFG-THETAFLGP 60
+Y GDLV++K+ GYP WP + P K +A +Y V FFG E A++
Sbjct: 219 KYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFE 278
Query: 61 KDLFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVK-ASGYQSSQKKSCVEEPEPEPEAA 119
K L + E + +F K + + + E +K SG +Q + + + E EAA
Sbjct: 279 KSLVAF-EGEGQFEKLCQESA-KQAPTKAEKIKLLKPISGKLRAQWEMGIVQAE---EAA 333
Query: 120 EGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEE 179
+++ A+ + G + P K E G G++ E S + AENP+
Sbjct: 334 SMSVEER-KAKFTFLYVGDQLHLNPQVAK-EAGIAAESLGEMAESSGVSEEAAENPKSVR 391
Query: 180 KEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEE 218
+E ++ R + + S P G+ PQ+ E +
Sbjct: 392 EECIPMKRRRRAKLCSSAETLESHPDIGKSTPQKTAEAD 430
>gi|19913350 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 50.8 bits (120), Expect = 1e-06
Identities = 56/219 (25%), Positives = 94/219 (42%), Gaps = 16/219 (7%)
Query: 9 EYKCGDLVFAKMKGYPHWPARIDEMP-------EAAVKSTANKYQVFFFG-THETAFLGP 60
+Y GDLV++K+ GYP WP + P K +A +Y V FFG E A++
Sbjct: 219 KYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFE 278
Query: 61 KDLFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVK-ASGYQSSQKKSCVEEPEPEPEAA 119
K L + E + +F K + + + E +K SG +Q + + + E EAA
Sbjct: 279 KSLVAF-EGEGQFEKLCQESA-KQAPTKAEKIKLLKPISGKLRAQWEMGIVQAE---EAA 333
Query: 120 EGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEE 179
+++ A+ + G + P K E G G++ E S + AENP+
Sbjct: 334 SMSVEER-KAKFTFLYVGDQLHLNPQVAK-EAGIAAESLGEMAESSGVSEEAAENPKSVR 391
Query: 180 KEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEE 218
+E ++ R + + S P G+ PQ+ E +
Sbjct: 392 EECIPMKRRRRAKLCSSAETLESHPDIGKSTPQKTAEAD 430
Score = 32.3 bits (72), Expect = 0.38
Identities = 16/60 (26%), Positives = 28/60 (46%), Gaps = 5/60 (8%)
Query: 14 DLVFAKMKGYPHWPARIDEMPEAA-----VKSTANKYQVFFFGTHETAFLGPKDLFPYEE 68
D+++ K+ Y WPA + +K ++ VFFFG+ + + +FPY E
Sbjct: 882 DIIWVKLGNYRWWPAEVCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYME 941
>gi|19913348 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 50.8 bits (120), Expect = 1e-06
Identities = 56/219 (25%), Positives = 94/219 (42%), Gaps = 16/219 (7%)
Query: 9 EYKCGDLVFAKMKGYPHWPARIDEMP-------EAAVKSTANKYQVFFFG-THETAFLGP 60
+Y GDLV++K+ GYP WP + P K +A +Y V FFG E A++
Sbjct: 219 KYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFE 278
Query: 61 KDLFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVK-ASGYQSSQKKSCVEEPEPEPEAA 119
K L + E + +F K + + + E +K SG +Q + + + E EAA
Sbjct: 279 KSLVAF-EGEGQFEKLCQESA-KQAPTKAEKIKLLKPISGKLRAQWEMGIVQAE---EAA 333
Query: 120 EGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEE 179
+++ A+ + G + P K E G G++ E S + AENP+
Sbjct: 334 SMSVEER-KAKFTFLYVGDQLHLNPQVAK-EAGIAAESLGEMAESSGVSEEAAENPKSVR 391
Query: 180 KEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEE 218
+E ++ R + + S P G+ PQ+ E +
Sbjct: 392 EECIPMKRRRRAKLCSSAETLESHPDIGKSTPQKTAEAD 430
Score = 32.3 bits (72), Expect = 0.38
Identities = 16/60 (26%), Positives = 28/60 (46%), Gaps = 5/60 (8%)
Query: 14 DLVFAKMKGYPHWPARIDEMPEAA-----VKSTANKYQVFFFGTHETAFLGPKDLFPYEE 68
D+++ K+ Y WPA + +K ++ VFFFG+ + + +FPY E
Sbjct: 882 DIIWVKLGNYRWWPAEVCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYME 941
>gi|109633019 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 50.8 bits (120), Expect = 1e-06
Identities = 56/219 (25%), Positives = 94/219 (42%), Gaps = 16/219 (7%)
Query: 9 EYKCGDLVFAKMKGYPHWPARIDEMP-------EAAVKSTANKYQVFFFG-THETAFLGP 60
+Y GDLV++K+ GYP WP + P K +A +Y V FFG E A++
Sbjct: 219 KYNVGDLVWSKVSGYPWWPCMVSADPLLHSYTKLKGQKKSARQYHVQFFGDAPERAWIFE 278
Query: 61 KDLFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVK-ASGYQSSQKKSCVEEPEPEPEAA 119
K L + E + +F K + + + E +K SG +Q + + + E EAA
Sbjct: 279 KSLVAF-EGEGQFEKLCQESA-KQAPTKAEKIKLLKPISGKLRAQWEMGIVQAE---EAA 333
Query: 120 EGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEE 179
+++ A+ + G + P K E G G++ E S + AENP+
Sbjct: 334 SMSVEER-KAKFTFLYVGDQLHLNPQVAK-EAGIAAESLGEMAESSGVSEEAAENPKSVR 391
Query: 180 KEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEE 218
+E ++ R + + S P G+ PQ+ E +
Sbjct: 392 EECIPMKRRRRAKLCSSAETLESHPDIGKSTPQKTAEAD 430
Score = 32.3 bits (72), Expect = 0.38
Identities = 16/60 (26%), Positives = 28/60 (46%), Gaps = 5/60 (8%)
Query: 14 DLVFAKMKGYPHWPARIDEMPEAA-----VKSTANKYQVFFFGTHETAFLGPKDLFPYEE 68
D+++ K+ Y WPA + +K ++ VFFFG+ + + +FPY E
Sbjct: 882 DIIWVKLGNYRWWPAEVCHPKNVPPNIQKMKHEIGEFPVFFFGSKDYYWTHQARVFPYME 941
>gi|157738619 smoothelin-like 1 [Homo sapiens]
Length = 512
Score = 48.9 bits (115), Expect = 4e-06
Identities = 53/230 (23%), Positives = 101/230 (43%), Gaps = 26/230 (11%)
Query: 2 SRSNRQKEYKCGDLVFAKMKGYPHW--PARIDEMPEAAVKSTANKYQVFFFGTHETAFLG 59
+ S +Q++ D + A+++G + +++ EA K A G E +G
Sbjct: 66 TESGKQEKAPAEDGMSAELQGEANGLDEVKVESQREAGGKEDAEAELKKEDGEKEETTVG 125
Query: 60 PKDLFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAA 119
+++ +E E +P + + L + K + +S QK + +PEP+A
Sbjct: 126 SQEMTGRKE--ETKSEPKEAEEKESTLASEKQKAEEKEAKPESGQKADANDRDKPEPKAT 183
Query: 120 EGDGDKK-------GNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEA 172
+ D K G + S E + DE AK +++K ++ +++ PKE
Sbjct: 184 VEEEDAKTASQEETGQRKECSTEPKEKATDEEAKAESQKAVVE-------DEAKAEPKE- 235
Query: 173 ENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEE 222
P+G+E+ + E E E ++ +EPGS P EE+E++ E+E
Sbjct: 236 --PDGKEEAKHGAKEEADAKEEAE-DAEEAEPGS----PSEEQEQDVEKE 278
Score = 40.4 bits (93), Expect = 0.001
Identities = 47/207 (22%), Positives = 78/207 (37%), Gaps = 29/207 (14%)
Query: 60 PKDLFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAA 119
P + E++ + G + +G + GL E++ +A G + ++ + E+ E E E
Sbjct: 65 PTESGKQEKAPAEDGMSAELQGEANGLDEVKVESQREAGGKEDAEAELKKEDGEKE-ETT 123
Query: 120 EGDGDKKGNAEGSSDE-------EGKLVIDEPAKEKNE---KGALKRRAGDLLEDSPKRP 169
G + G E + E E L ++ E+ E + K A D + PK
Sbjct: 124 VGSQEMTGRKEETKSEPKEAEEKESTLASEKQKAEEKEAKPESGQKADANDRDKPEPKAT 183
Query: 170 KEAENPE-------GEEKEAATLEVERPLPMEV-----------EKNSTPSEPGSGRGPP 211
E E+ + G+ KE +T E+ E E + P EP
Sbjct: 184 VEEEDAKTASQEETGQRKECSTEPKEKATDEEAKAESQKAVVEDEAKAEPKEPDGKEEAK 243
Query: 212 QEEEEEEDEEEEATKEDAEAPGIRDHE 238
+EE D +EEA + PG E
Sbjct: 244 HGAKEEADAKEEAEDAEEAEPGSPSEE 270
Score = 35.4 bits (80), Expect = 0.044
Identities = 34/155 (21%), Positives = 63/155 (40%), Gaps = 10/155 (6%)
Query: 88 EIENNPTVKASGYQS---SQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEP 144
E P KA+ ++ SQK +E + EP+ +G + K A+ +D + + E
Sbjct: 202 ECSTEPKEKATDEEAKAESQKAVVEDEAKAEPKEPDGKEEAKHGAKEEADAKEEAEDAEE 261
Query: 145 AK-----EKNEKGALKRRAGD--LLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEK 197
A+ E+ E+ K G ++ SP+ E+ EG L + +
Sbjct: 262 AEPGSPSEEQEQDVEKEPEGGAGVIPSSPEEWPESPTGEGHNLSTDGLGPDCVASGQTSP 321
Query: 198 NSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAP 232
+++ S P P E +++E+A + AP
Sbjct: 322 SASESSPSDVPQSPPESPSSGEKKEKAPERRVSAP 356
>gi|13540523 nucleosomal binding protein 1 [Homo sapiens]
Length = 282
Score = 48.5 bits (114), Expect = 5e-06
Identities = 38/144 (26%), Positives = 62/144 (43%), Gaps = 20/144 (13%)
Query: 101 QSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKEK------------ 148
+ QK+ ++ E + EA + D D+KG +G D+ G E AKEK
Sbjct: 127 EEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGN-EKGEDAKEKEDGKKGEDGKGN 185
Query: 149 ----NEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEP 204
EKG ++ D E + E +G++KE ++V+ E E+ +
Sbjct: 186 GEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKED---EKEREDGKEDE 242
Query: 205 GSGRGPPQEEEEEEDEEEEATKED 228
G +E+E+ EEEE +ED
Sbjct: 243 GGNEEEAGKEKEDLKEEEEGKEED 266
Score = 34.7 bits (78), Expect = 0.076
Identities = 36/149 (24%), Positives = 61/149 (40%), Gaps = 29/149 (19%)
Query: 93 PTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKG 152
P VK SS+K + + + E + D A + +E V++E E + G
Sbjct: 32 PEVKPKRTSSSRKM------KTKSDMMEENIDTSAQAVAETKQEA--VVEEDYNENAKNG 83
Query: 153 ALKRRAG-----DLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSG 207
K +++E + ++A GE+KEA EV KN +
Sbjct: 84 EAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEV---------KNEEEDQ---- 130
Query: 208 RGPPQEEEEEEDEEEEATKEDAEAPGIRD 236
++EE++ +E+ EA KED + G D
Sbjct: 131 ---KEDEEDQNEEKGEAGKEDKDEKGEED 156
Score = 33.1 bits (74), Expect = 0.22
Identities = 26/84 (30%), Positives = 41/84 (48%), Gaps = 3/84 (3%)
Query: 67 EESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKK 126
E+ KEK G+ K + + + + N K G + K V+E E E E +G D+
Sbjct: 187 EDGKEK-GEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKERE--DGKEDEG 243
Query: 127 GNAEGSSDEEGKLVIDEPAKEKNE 150
GN E + E+ L +E KE++E
Sbjct: 244 GNEEEAGKEKEDLKEEEEGKEEDE 267
Score = 32.7 bits (73), Expect = 0.29
Identities = 39/161 (24%), Positives = 66/161 (40%), Gaps = 16/161 (9%)
Query: 88 EIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGN--AEGSSDEEGKLVIDEPA 145
E N K + +S+K+ + E +A E G+KK AE ++EE + E
Sbjct: 78 ENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQ---KEDE 134
Query: 146 KEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPG 205
+++NE+ K AG +D E+ G EK E E E K +
Sbjct: 135 EDQNEE---KGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKE 191
Query: 206 SGRGPPQEEE--------EEEDEEEEATKEDAEAPGIRDHE 238
G +EE+ E ED +E+ K++ + +++ E
Sbjct: 192 KGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDE 232
Score = 30.8 bits (68), Expect = 1.1
Identities = 23/90 (25%), Positives = 38/90 (42%), Gaps = 4/90 (4%)
Query: 96 KASGYQSSQKKSCVEEPEPEPEAAEG----DGDKKGNAEGSSDEEGKLVIDEPAKEKNEK 151
K +G +K +E E E +G DG +KG+ + D + K E K ++
Sbjct: 183 KGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDE 242
Query: 152 GALKRRAGDLLEDSPKRPKEAENPEGEEKE 181
G + AG ED + + E E +E +
Sbjct: 243 GGNEEEAGKEKEDLKEEEEGKEEDEIKEDD 272
>gi|4759128 solute carrier family 24 (sodium/potassium/calcium
exchanger), member 1 [Homo sapiens]
Length = 1099
Score = 47.8 bits (112), Expect = 9e-06
Identities = 35/131 (26%), Positives = 61/131 (46%), Gaps = 3/131 (2%)
Query: 103 SQKKSCVEEPEPEPEAA-EGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDL 161
++ +S E P E E A EG+ ++K E + EG+ +E ++ + + +
Sbjct: 748 AEAESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNE 807
Query: 162 LEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGR--GPPQEEEEEED 219
ED + E +G E E + E+ E + + E G G G +EEEEEE+
Sbjct: 808 GEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEE 867
Query: 220 EEEEATKEDAE 230
E+EE +E+ +
Sbjct: 868 EQEEEEEEEEQ 878
Score = 47.0 bits (110), Expect = 1e-05
Identities = 50/183 (27%), Positives = 75/183 (40%), Gaps = 27/183 (14%)
Query: 59 GPKDLFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEA 118
G +D+ E + E G+ + G EG E ++ + G ++ + EE E E EA
Sbjct: 743 GQEDVAEAESTGEMPGEEGETAG--EGETEEKSGGETQPEGEGETETQGKGEECEDENEA 800
Query: 119 AEGDGDKKGNAEGSSD-EEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEG 177
EG GD +G EG E+G++ +E E E A E + ++ +
Sbjct: 801 -EGKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDS 859
Query: 178 EEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAPGIRDH 237
EE+E E E +EEEEEE EEEE +E+ E G +
Sbjct: 860 EEEEEEEEEQE-----------------------EEEEEEEQEEEEEEEEEEEEKGNEEP 896
Query: 238 ESL 240
SL
Sbjct: 897 LSL 899
>gi|156104891 general transcription factor IIF, polypeptide 1, 74kDa
[Homo sapiens]
Length = 517
Score = 47.4 bits (111), Expect = 1e-05
Identities = 44/163 (26%), Positives = 77/163 (47%), Gaps = 20/163 (12%)
Query: 67 EESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSS-QKKSCVEEPEPEPEAAEGDGDK 125
EE KEK G+ RK + ++E++ + + +S ++ V + + + A+G G K
Sbjct: 191 EEEKEKRGR---RKASELRIHDLEDDLEMSSDASDASGEEGGRVPKAKKKAPLAKG-GRK 246
Query: 126 KGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATL 185
K +GS DE A E ++ G + + D + D +E E E K A
Sbjct: 247 KKKKKGSDDE---------AFEDSDDGDFEGQEVDYMSDGSSSSQE----EPESKAKAPQ 293
Query: 186 EVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKED 228
+ E P V++ S SE PP+E++EEE+E++ T ++
Sbjct: 294 QEEGP--KGVDEQSDSSEESEEEKPPEEDKEEEEEKKAPTPQE 334
Score = 38.9 bits (89), Expect = 0.004
Identities = 39/150 (26%), Positives = 64/150 (42%), Gaps = 12/150 (8%)
Query: 75 KPNKRKGFSEGLWEIENNPTVKAS--GYQSSQKKSCVEEPEPEPEAAEGDGDKKG---NA 129
K K+KG + +E ++ + Y S S EEPE + +A + + KG +
Sbjct: 246 KKKKKKGSDDEAFEDSDDGDFEGQEVDYMSDGSSSSQEEPESKAKAPQQEEGPKGVDEQS 305
Query: 130 EGSSDEEGKLVIDEPAKEKNEKGA----LKRRAGDLLEDSPKRPKEAENPEGEEKEAATL 185
+ S + E + +E +E+ EK A K+R D E+S E + + E A +
Sbjct: 306 DSSEESEEEKPPEEDKEEEEEKKAPTPQEKKRRKDSSEESDS--SEESDIDSEASSALFM 363
Query: 186 EVERPLPMEVEKNSTPSEPGSGR-GPPQEE 214
++ P K S S G+ R G P E
Sbjct: 364 AKKKTPPKRERKPSGGSSRGNSRPGTPSAE 393
Score = 37.7 bits (86), Expect = 0.009
Identities = 32/130 (24%), Positives = 55/130 (42%), Gaps = 18/130 (13%)
Query: 99 GYQSSQKKSCVEEPEPEPEAAEGDG---DKKGNAEGSSDEEGKLVIDEPAKEKNEKGALK 155
G + +KK +E + + + +G D + SS EE + P +E+ KG +
Sbjct: 244 GRKKKKKKGSDDEAFEDSDDGDFEGQEVDYMSDGSSSSQEEPESKAKAPQQEEGPKG-VD 302
Query: 156 RRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEE 215
++ E ++P E + E EEK+A P P E ++ SE +
Sbjct: 303 EQSDSSEESEEEKPPEEDKEEEEEKKA-------PTPQEKKRRKDSSE-------ESDSS 348
Query: 216 EEEDEEEEAT 225
EE D + EA+
Sbjct: 349 EESDIDSEAS 358
Score = 37.4 bits (85), Expect = 0.012
Identities = 40/175 (22%), Positives = 68/175 (38%), Gaps = 21/175 (12%)
Query: 67 EESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKK 126
EE++E++ + NK + + + + +K+ + E E D +
Sbjct: 158 EEAEEEWERRNKVLNHFSIMQQRRLKDQDQDEDEEEKEKRGRRKASELRIHDLEDDLEMS 217
Query: 127 GNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLE 186
+A +S EEG V K KG K+ K+ K +++ E+ + E
Sbjct: 218 SDASDASGEEGGRVPKAKKKAPLAKGGRKK----------KKKKGSDDEAFEDSDDGDFE 267
Query: 187 VERPLPMEVEKNSTPSEPGSGRGPPQEEE-----------EEEDEEEEATKEDAE 230
+ M +S+ EP S PQ+EE EE EEE+ +ED E
Sbjct: 268 GQEVDYMSDGSSSSQEEPESKAKAPQQEEGPKGVDEQSDSSEESEEEKPPEEDKE 322
>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
Length = 709
Score = 47.0 bits (110), Expect = 1e-05
Identities = 47/183 (25%), Positives = 78/183 (42%), Gaps = 19/183 (10%)
Query: 61 KDLFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAE 120
K Y+ + + + NKR +I + + Y++ +K+CV + +PE A
Sbjct: 90 KSATEYKNEEYQRSERNKRLDADR---KIRLSSSASREPYKNQPEKTCVRKRDPERRA-- 144
Query: 121 GDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLED-----SPKRPKEAENP 175
K +GS E L +D A ++ + + + D S ++ N
Sbjct: 145 ----KSPTPDGS--ERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNT 198
Query: 176 EGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAPGIR 235
E EE E +VE EVE+++ E G +EEEEEE+EEEE +E+ R
Sbjct: 199 ENEE-EGVEEDVEED--EEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDER 255
Query: 236 DHE 238
D +
Sbjct: 256 DQK 258
Score = 27.7 bits (60), Expect = 9.2
Identities = 23/97 (23%), Positives = 40/97 (41%), Gaps = 9/97 (9%)
Query: 134 DEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPM 193
+++ +L E ++KNEK KR++ + KR K P ++ V +PL
Sbjct: 25 EQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQK----PSVHSRQL----VSKPLSS 76
Query: 194 EVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAE 230
V N G+ + + EE E + DA+
Sbjct: 77 SVSNNKRIVST-KGKSATEYKNEEYQRSERNKRLDAD 112
>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
Length = 727
Score = 47.0 bits (110), Expect = 1e-05
Identities = 47/183 (25%), Positives = 78/183 (42%), Gaps = 19/183 (10%)
Query: 61 KDLFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAE 120
K Y+ + + + NKR +I + + Y++ +K+CV + +PE A
Sbjct: 90 KSATEYKNEEYQRSERNKRLDADR---KIRLSSSASREPYKNQPEKTCVRKRDPERRA-- 144
Query: 121 GDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLED-----SPKRPKEAENP 175
K +GS E L +D A ++ + + + D S ++ N
Sbjct: 145 ----KSPTPDGS--ERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNT 198
Query: 176 EGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAPGIR 235
E EE E +VE EVE+++ E G +EEEEEE+EEEE +E+ R
Sbjct: 199 ENEE-EGVEEDVEED--EEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDER 255
Query: 236 DHE 238
D +
Sbjct: 256 DQK 258
Score = 27.7 bits (60), Expect = 9.2
Identities = 23/97 (23%), Positives = 40/97 (41%), Gaps = 9/97 (9%)
Query: 134 DEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPM 193
+++ +L E ++KNEK KR++ + KR K P ++ V +PL
Sbjct: 25 EQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQK----PSVHSRQL----VSKPLSS 76
Query: 194 EVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAE 230
V N G+ + + EE E + DA+
Sbjct: 77 SVSNNKRIVST-KGKSATEYKNEEYQRSERNKRLDAD 112
>gi|15721939 metastatic lymph node 51 [Homo sapiens]
Length = 703
Score = 46.6 bits (109), Expect = 2e-05
Identities = 37/130 (28%), Positives = 65/130 (50%), Gaps = 13/130 (10%)
Query: 95 VKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGAL 154
V++ G +S+++ C E E +A D + +AE S EEG E ++E+N K L
Sbjct: 64 VESGGAKSAEESECESEDGIEGDAVLSDYE---SAEDSEGEEG-----EYSEEENSKVEL 115
Query: 155 KRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEE 214
K A D + S K K E P+ + +T+ ER + ++++ P E G+ P+
Sbjct: 116 KSEANDAVNSSTKEEKGEEKPDTK----STVTGERQ-SGDGQESTEPVENKVGKKGPKHL 170
Query: 215 EEEEDEEEEA 224
+++ED + A
Sbjct: 171 DDDEDRKNPA 180
>gi|13699811 WHSC1L1 protein isoform long [Homo sapiens]
Length = 1437
Score = 45.8 bits (107), Expect = 3e-05
Identities = 62/234 (26%), Positives = 97/234 (41%), Gaps = 39/234 (16%)
Query: 9 EYKCGDLVFAKMKGYPHWPARIDEMPEAAVKSTAN-----KYQVFFFGTH-ETAFLGPKD 62
+++ GDLV++K+ YP WP + P+ V + N +Y V FF E A++ K
Sbjct: 267 KFQVGDLVWSKVGTYPWWPCMVSSDPQLEVHTKINTRGAREYHVQFFSNQPERAWVHEKR 326
Query: 63 LFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGD 122
+ Y+ K+ + E L E T +AS + QK + +P P+ E A+ D
Sbjct: 327 VREYKGHKQ----------YEELLAE----ATKQASNHSEKQK---IRKPRPQRERAQWD 369
Query: 123 -----GDK--KGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENP 175
+K K E ++ + ID+ +E + A K A +RP+ N
Sbjct: 370 IGIAHAEKALKMTREERIEQYTFIYIDKQPEEALSQ-AKKSVASKTEVKKTRRPRSVLNT 428
Query: 176 EGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDA 229
+ E+ A EV L +ST S R EEEE + A K A
Sbjct: 429 QPEQTNAG--EVASSL------SSTEIRRHSQRRHTSAEEEEPPPVKIAWKTAA 474
Score = 40.0 bits (92), Expect = 0.002
Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 9/93 (9%)
Query: 3 RSNRQKEYKCGDLVFAKMKGYPHWPARIDEMPEA-----AVKSTANKYQVFFFGTHETAF 57
++ ++ YK +V+ K+ Y WPA I +K + VFFFG+H+ +
Sbjct: 953 KAGKKLHYK--QIVWVKLGNYRWWPAEICNPRSVPLNIQGLKHDLGDFPVFFFGSHDYYW 1010
Query: 58 LGPKDLFPYEESKEKF--GKPNKRKGFSEGLWE 88
+ +FPY E + F G+ + K F + L E
Sbjct: 1011 VHQGRVFPYVEGDKSFAEGQTSINKTFKKALEE 1043
>gi|13699813 WHSC1L1 protein isoform short [Homo sapiens]
Length = 645
Score = 45.8 bits (107), Expect = 3e-05
Identities = 62/234 (26%), Positives = 97/234 (41%), Gaps = 39/234 (16%)
Query: 9 EYKCGDLVFAKMKGYPHWPARIDEMPEAAVKSTAN-----KYQVFFFGTH-ETAFLGPKD 62
+++ GDLV++K+ YP WP + P+ V + N +Y V FF E A++ K
Sbjct: 267 KFQVGDLVWSKVGTYPWWPCMVSSDPQLEVHTKINTRGAREYHVQFFSNQPERAWVHEKR 326
Query: 63 LFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGD 122
+ Y+ K+ + E L E T +AS + QK + +P P+ E A+ D
Sbjct: 327 VREYKGHKQ----------YEELLAE----ATKQASNHSEKQK---IRKPRPQRERAQWD 369
Query: 123 -----GDK--KGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENP 175
+K K E ++ + ID+ +E + A K A +RP+ N
Sbjct: 370 IGIAHAEKALKMTREERIEQYTFIYIDKQPEEALSQ-AKKSVASKTEVKKTRRPRSVLNT 428
Query: 176 EGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDA 229
+ E+ A EV L +ST S R EEEE + A K A
Sbjct: 429 QPEQTNAG--EVASSL------SSTEIRRHSQRRHTSAEEEEPPPVKIAWKTAA 474
>gi|21237808 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin c2 isoform b [Homo sapiens]
Length = 1130
Score = 45.4 bits (106), Expect = 4e-05
Identities = 34/121 (28%), Positives = 59/121 (48%), Gaps = 22/121 (18%)
Query: 115 EPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAEN 174
EPE E G+ + EG + +E K EP + + GA++ A + ++PK+ +E
Sbjct: 778 EPERIEESGNDEARVEGQATDEKK----EPKEPREGGGAIEEEAKEKTSEAPKKDEE--- 830
Query: 175 PEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAPGI 234
+G+E ++ EK S S+ G P++E+E ++ +EE KE E+ G
Sbjct: 831 -KGKEGDS-------------EKESEKSD-GDPIVDPEKEKEPKEGQEEVLKEVVESEGE 875
Query: 235 R 235
R
Sbjct: 876 R 876
Score = 31.6 bits (70), Expect = 0.64
Identities = 21/76 (27%), Positives = 32/76 (42%), Gaps = 11/76 (14%)
Query: 164 DSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEE 223
D P+R +E+ N E + AT ++ P EP G G +EE +E+ E
Sbjct: 777 DEPERIEESGNDEARVEGQAT-----------DEKKEPKEPREGGGAIEEEAKEKTSEAP 825
Query: 224 ATKEDAEAPGIRDHES 239
E+ G + ES
Sbjct: 826 KKDEEKGKEGDSEKES 841
Score = 30.0 bits (66), Expect = 1.9
Identities = 25/105 (23%), Positives = 42/105 (40%), Gaps = 15/105 (14%)
Query: 88 EIENNPTVKASGYQSSQKKS---------CVEEPEPEPEAAEGDGDKKGNAEGSSDEE-- 136
E N + G + +KK +EE E + D++ EG S++E
Sbjct: 783 EESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKESE 842
Query: 137 ---GKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGE 178
G ++D P KEK K + +++E +R + E GE
Sbjct: 843 KSDGDPIVD-PEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGE 886
>gi|21237805 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin c2 isoform a [Homo sapiens]
Length = 1214
Score = 45.4 bits (106), Expect = 4e-05
Identities = 34/121 (28%), Positives = 59/121 (48%), Gaps = 22/121 (18%)
Query: 115 EPEAAEGDGDKKGNAEGSSDEEGKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAEN 174
EPE E G+ + EG + +E K EP + + GA++ A + ++PK+ +E
Sbjct: 747 EPERIEESGNDEARVEGQATDEKK----EPKEPREGGGAIEEEAKEKTSEAPKKDEE--- 799
Query: 175 PEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAPGI 234
+G+E ++ EK S S+ G P++E+E ++ +EE KE E+ G
Sbjct: 800 -KGKEGDS-------------EKESEKSD-GDPIVDPEKEKEPKEGQEEVLKEVVESEGE 844
Query: 235 R 235
R
Sbjct: 845 R 845
Score = 31.6 bits (70), Expect = 0.64
Identities = 21/76 (27%), Positives = 32/76 (42%), Gaps = 11/76 (14%)
Query: 164 DSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEE 223
D P+R +E+ N E + AT ++ P EP G G +EE +E+ E
Sbjct: 746 DEPERIEESGNDEARVEGQAT-----------DEKKEPKEPREGGGAIEEEAKEKTSEAP 794
Query: 224 ATKEDAEAPGIRDHES 239
E+ G + ES
Sbjct: 795 KKDEEKGKEGDSEKES 810
Score = 30.0 bits (66), Expect = 1.9
Identities = 25/105 (23%), Positives = 42/105 (40%), Gaps = 15/105 (14%)
Query: 88 EIENNPTVKASGYQSSQKKS---------CVEEPEPEPEAAEGDGDKKGNAEGSSDEE-- 136
E N + G + +KK +EE E + D++ EG S++E
Sbjct: 752 EESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKESE 811
Query: 137 ---GKLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGE 178
G ++D P KEK K + +++E +R + E GE
Sbjct: 812 KSDGDPIVD-PEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGE 855
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.302 0.126 0.357
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,087,677
Number of Sequences: 37866
Number of extensions: 720349
Number of successful extensions: 14145
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 547
Number of HSP's successfully gapped in prelim test: 676
Number of HSP's that attempted gapping in prelim test: 5605
Number of HSP's gapped (non-prelim): 4951
length of query: 240
length of database: 18,247,518
effective HSP length: 99
effective length of query: 141
effective length of database: 14,498,784
effective search space: 2044328544
effective search space used: 2044328544
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.7 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.