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Search of human proteins with 4758472
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4758472 G protein pathway suppressor 2 [Homo sapiens]
(327 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4758472 G protein pathway suppressor 2 [Homo sapiens] 664 0.0
gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens] 62 7e-10
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 60 3e-09
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 60 3e-09
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 60 3e-09
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 60 3e-09
gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens] 59 5e-09
gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens] 59 5e-09
gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens] 59 5e-09
gi|148746195 trichohyalin [Homo sapiens] 56 5e-08
gi|239752551 PREDICTED: hypothetical protein [Homo sapiens] 55 7e-08
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 54 1e-07
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 54 2e-07
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 53 3e-07
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 51 1e-06
gi|154354979 myosin X [Homo sapiens] 51 2e-06
gi|92859701 myosin VI [Homo sapiens] 50 2e-06
gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo ... 50 2e-06
gi|221219020 NYD-SP11 protein [Homo sapiens] 50 3e-06
gi|56549694 enabled homolog isoform a [Homo sapiens] 50 3e-06
gi|39930375 enabled homolog isoform b [Homo sapiens] 50 3e-06
gi|22035606 mitogen-activated protein kinase kinase kinase kinas... 50 3e-06
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 50 4e-06
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 50 4e-06
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 50 4e-06
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 50 4e-06
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 49 5e-06
gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo sa... 49 5e-06
gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo sa... 49 5e-06
gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo sa... 49 5e-06
>gi|4758472 G protein pathway suppressor 2 [Homo sapiens]
Length = 327
Score = 664 bits (1712), Expect = 0.0
Identities = 327/327 (100%), Positives = 327/327 (100%)
Query: 1 MPALLERPKLSNAMARALHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERM 60
MPALLERPKLSNAMARALHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERM
Sbjct: 1 MPALLERPKLSNAMARALHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERM 60
Query: 61 SLEETKEQILKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQSDLTTLTSAAYQQSL 120
SLEETKEQILKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQSDLTTLTSAAYQQSL
Sbjct: 61 SLEETKEQILKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQSDLTTLTSAAYQQSL 120
Query: 121 TVHTGTHLLSMQGSPGGHNRPGTLMAADRAKQMFGPQVLTTRHYVGSAAAFAGTPEHGQF 180
TVHTGTHLLSMQGSPGGHNRPGTLMAADRAKQMFGPQVLTTRHYVGSAAAFAGTPEHGQF
Sbjct: 121 TVHTGTHLLSMQGSPGGHNRPGTLMAADRAKQMFGPQVLTTRHYVGSAAAFAGTPEHGQF 180
Query: 181 QGSPGGAYGTAQPPPHYGPTQPAYSPSQQLRAPSAFPAVQYLSQPQPQPYAVHGHFQPTQ 240
QGSPGGAYGTAQPPPHYGPTQPAYSPSQQLRAPSAFPAVQYLSQPQPQPYAVHGHFQPTQ
Sbjct: 181 QGSPGGAYGTAQPPPHYGPTQPAYSPSQQLRAPSAFPAVQYLSQPQPQPYAVHGHFQPTQ 240
Query: 241 TGFLQPGGALSLQKQMEHANQQTGFSDSSSLRPMHPQALHPAPGLLASPQLPVQMQPAGK 300
TGFLQPGGALSLQKQMEHANQQTGFSDSSSLRPMHPQALHPAPGLLASPQLPVQMQPAGK
Sbjct: 241 TGFLQPGGALSLQKQMEHANQQTGFSDSSSLRPMHPQALHPAPGLLASPQLPVQMQPAGK 300
Query: 301 SGFAATSQPGPRLPFIQHSQNPRFYHK 327
SGFAATSQPGPRLPFIQHSQNPRFYHK
Sbjct: 301 SGFAATSQPGPRLPFIQHSQNPRFYHK 327
>gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens]
Length = 1312
Score = 62.0 bits (149), Expect = 7e-10
Identities = 60/224 (26%), Positives = 104/224 (46%), Gaps = 15/224 (6%)
Query: 20 RHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLAL 79
+H++ +R+R+ +E++E + +E++ + E+E+RK +E E++ LE+ Q L+ EE+
Sbjct: 388 KHLLHQRQRRIEEQKEERRRVEEQQRREREQRKLQEKEQQRRLEDM--QALRREEERRQA 445
Query: 80 QEEKHQLFLQLKKVLHEEEKRR--RKEQSDLTTLTSAAYQQSLTVHTGTHLLSMQGSPGG 137
+ E+ QL++ E +R ++E + L +L QQ L LL P
Sbjct: 446 EREQEYKRKQLEEQRQSERLQRQLQQEHAYLKSLQQQQQQQQLQKQQQQQLLPGDRKPLY 505
Query: 138 HNRPGTLMAADR---AKQMFGPQVLTTRHYVGSAAAFAGT--PEHGQFQGSPGGAYGTAQ 192
H G + AD+ A+++ + + A + G+ PE Q SPG +Q
Sbjct: 506 HYGRG-MNPADKPAWAREVEERTRMNKQQNSPLAKSKPGSTGPEPPIPQASPGPPGPLSQ 564
Query: 193 PPPHYGPTQPAYSPSQQL-----RAPSAFPAVQYLSQPQPQPYA 231
PP P +P P + L R +AFPA P P A
Sbjct: 565 TPPMQRPVEPQEGPHKSLQDQPTRNLAAFPASHDPDPAIPAPTA 608
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 59.7 bits (143), Expect = 3e-09
Identities = 34/103 (33%), Positives = 62/103 (60%), Gaps = 4/103 (3%)
Query: 5 LERPKLSNAMARALHRHIMMERERK---RQEEEEVDKMMEQKMKEEQERRKKKEMEERMS 61
L R K A+ R + I + R+R+ RQ++EE + +E++ +EE+ERRK++E+ +
Sbjct: 779 LARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQE 838
Query: 62 LEETKEQILKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKE 104
EE + + EE L+E + ++ + ++ HEEE+R+RKE
Sbjct: 839 -EEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKE 880
Score = 47.4 bits (111), Expect = 2e-05
Identities = 33/120 (27%), Positives = 63/120 (52%), Gaps = 18/120 (15%)
Query: 2 PALLERPKLSNAMARALH--------RHIMMERERKRQEEEEVDKMMEQKMKEEQERRKK 53
PAL + +L A A L R E ERKRQEE + + E+ ++ +QE +K
Sbjct: 715 PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEE--LRRQQEEILRRQQEEERK 772
Query: 54 KEMEERMSLEETKEQILKLEEKLLALQ--------EEKHQLFLQLKKVLHEEEKRRRKEQ 105
+ EE ++ + +E + + E+ +AL+ +++ + +L++ EEE+RR++E+
Sbjct: 773 RREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE 832
Score = 38.1 bits (87), Expect = 0.011
Identities = 34/118 (28%), Positives = 60/118 (50%), Gaps = 14/118 (11%)
Query: 6 ERPKLSNAMARALHRHIMMERERKRQEEEEVDKMMEQKMK---EEQERRKKKEMEERMSL 62
ER + A+ R R E E +R++EE + K E+ K EE+E +++ E E R+ +
Sbjct: 806 ERQQQEEALRRLEERR--REEEERRKQEELLRKQEEEAAKWAREEEEAQRRLE-ENRLRM 862
Query: 63 EETKEQILKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQSDLTTLTSAAYQQSL 120
EE ++ EE + ++ +L +Q +K E ++R+++Q L L QQ L
Sbjct: 863 EEEAARLRHEEE-----ERKRKELEVQRQK---ELMRQRQQQQEALRRLQQQQQQQQL 912
Score = 37.4 bits (85), Expect = 0.018
Identities = 28/82 (34%), Positives = 44/82 (53%), Gaps = 11/82 (13%)
Query: 27 ERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKHQL 86
E+ +Q E+ +EQ+ + E E R K+E EER EE + Q +E++L Q+E+
Sbjct: 718 EQLQQLEKAKAAKLEQE-RREAEMRAKREEEERKRQEELRRQ----QEEILRRQQEEE-- 770
Query: 87 FLQLKKVLHEEEKRRRKEQSDL 108
+K EEE RRK++ L
Sbjct: 771 ----RKRREEEELARRKQEEAL 788
Score = 35.8 bits (81), Expect = 0.053
Identities = 28/127 (22%), Positives = 60/127 (47%), Gaps = 25/127 (19%)
Query: 5 LERPKLSNAMARALHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEE 64
LE +L A RH ER+RK E + ++M Q+ ++++ R+ ++ +++ L +
Sbjct: 855 LEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQ 914
Query: 65 TK------------------------EQILKLEEKL-LALQEEKHQLFLQLKKVLHEEEK 99
K +I KLEE+ L+EE+ + +L K L ++++
Sbjct: 915 MKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQ 974
Query: 100 RRRKEQS 106
+++++ S
Sbjct: 975 QQQQKLS 981
Score = 34.7 bits (78), Expect = 0.12
Identities = 23/71 (32%), Positives = 41/71 (57%), Gaps = 3/71 (4%)
Query: 25 ERERKRQEEEEVDKMMEQ--KMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEE 82
E E +R+ EE +M E+ +++ E+E RK+KE+E + +E Q + +E L LQ++
Sbjct: 848 EEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQ-KELMRQRQQQQEALRRLQQQ 906
Query: 83 KHQLFLQLKKV 93
+ Q L K+
Sbjct: 907 QQQQQLAQMKL 917
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 59.7 bits (143), Expect = 3e-09
Identities = 34/103 (33%), Positives = 62/103 (60%), Gaps = 4/103 (3%)
Query: 5 LERPKLSNAMARALHRHIMMERERK---RQEEEEVDKMMEQKMKEEQERRKKKEMEERMS 61
L R K A+ R + I + R+R+ RQ++EE + +E++ +EE+ERRK++E+ +
Sbjct: 806 LARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQE 865
Query: 62 LEETKEQILKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKE 104
EE + + EE L+E + ++ + ++ HEEE+R+RKE
Sbjct: 866 -EEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKE 907
Score = 47.4 bits (111), Expect = 2e-05
Identities = 33/120 (27%), Positives = 63/120 (52%), Gaps = 18/120 (15%)
Query: 2 PALLERPKLSNAMARALH--------RHIMMERERKRQEEEEVDKMMEQKMKEEQERRKK 53
PAL + +L A A L R E ERKRQEE + + E+ ++ +QE +K
Sbjct: 742 PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEE--LRRQQEEILRRQQEEERK 799
Query: 54 KEMEERMSLEETKEQILKLEEKLLALQ--------EEKHQLFLQLKKVLHEEEKRRRKEQ 105
+ EE ++ + +E + + E+ +AL+ +++ + +L++ EEE+RR++E+
Sbjct: 800 RREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE 859
Score = 38.1 bits (87), Expect = 0.011
Identities = 34/118 (28%), Positives = 60/118 (50%), Gaps = 14/118 (11%)
Query: 6 ERPKLSNAMARALHRHIMMERERKRQEEEEVDKMMEQKMK---EEQERRKKKEMEERMSL 62
ER + A+ R R E E +R++EE + K E+ K EE+E +++ E E R+ +
Sbjct: 833 ERQQQEEALRRLEERR--REEEERRKQEELLRKQEEEAAKWAREEEEAQRRLE-ENRLRM 889
Query: 63 EETKEQILKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQSDLTTLTSAAYQQSL 120
EE ++ EE + ++ +L +Q +K E ++R+++Q L L QQ L
Sbjct: 890 EEEAARLRHEEE-----ERKRKELEVQRQK---ELMRQRQQQQEALRRLQQQQQQQQL 939
Score = 37.4 bits (85), Expect = 0.018
Identities = 28/82 (34%), Positives = 44/82 (53%), Gaps = 11/82 (13%)
Query: 27 ERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKHQL 86
E+ +Q E+ +EQ+ + E E R K+E EER EE + Q +E++L Q+E+
Sbjct: 745 EQLQQLEKAKAAKLEQE-RREAEMRAKREEEERKRQEELRRQ----QEEILRRQQEEE-- 797
Query: 87 FLQLKKVLHEEEKRRRKEQSDL 108
+K EEE RRK++ L
Sbjct: 798 ----RKRREEEELARRKQEEAL 815
Score = 35.8 bits (81), Expect = 0.053
Identities = 28/127 (22%), Positives = 60/127 (47%), Gaps = 25/127 (19%)
Query: 5 LERPKLSNAMARALHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEE 64
LE +L A RH ER+RK E + ++M Q+ ++++ R+ ++ +++ L +
Sbjct: 882 LEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQ 941
Query: 65 TK------------------------EQILKLEEKL-LALQEEKHQLFLQLKKVLHEEEK 99
K +I KLEE+ L+EE+ + +L K L ++++
Sbjct: 942 MKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQ 1001
Query: 100 RRRKEQS 106
+++++ S
Sbjct: 1002 QQQQKLS 1008
Score = 34.7 bits (78), Expect = 0.12
Identities = 23/71 (32%), Positives = 41/71 (57%), Gaps = 3/71 (4%)
Query: 25 ERERKRQEEEEVDKMMEQ--KMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEE 82
E E +R+ EE +M E+ +++ E+E RK+KE+E + +E Q + +E L LQ++
Sbjct: 875 EEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQ-KELMRQRQQQQEALRRLQQQ 933
Query: 83 KHQLFLQLKKV 93
+ Q L K+
Sbjct: 934 QQQQQLAQMKL 944
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 59.7 bits (143), Expect = 3e-09
Identities = 34/103 (33%), Positives = 62/103 (60%), Gaps = 4/103 (3%)
Query: 5 LERPKLSNAMARALHRHIMMERERK---RQEEEEVDKMMEQKMKEEQERRKKKEMEERMS 61
L R K A+ R + I + R+R+ RQ++EE + +E++ +EE+ERRK++E+ +
Sbjct: 785 LARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQE 844
Query: 62 LEETKEQILKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKE 104
EE + + EE L+E + ++ + ++ HEEE+R+RKE
Sbjct: 845 -EEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKE 886
Score = 47.4 bits (111), Expect = 2e-05
Identities = 33/120 (27%), Positives = 63/120 (52%), Gaps = 18/120 (15%)
Query: 2 PALLERPKLSNAMARALH--------RHIMMERERKRQEEEEVDKMMEQKMKEEQERRKK 53
PAL + +L A A L R E ERKRQEE + + E+ ++ +QE +K
Sbjct: 721 PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEE--LRRQQEEILRRQQEEERK 778
Query: 54 KEMEERMSLEETKEQILKLEEKLLALQ--------EEKHQLFLQLKKVLHEEEKRRRKEQ 105
+ EE ++ + +E + + E+ +AL+ +++ + +L++ EEE+RR++E+
Sbjct: 779 RREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE 838
Score = 38.1 bits (87), Expect = 0.011
Identities = 34/118 (28%), Positives = 60/118 (50%), Gaps = 14/118 (11%)
Query: 6 ERPKLSNAMARALHRHIMMERERKRQEEEEVDKMMEQKMK---EEQERRKKKEMEERMSL 62
ER + A+ R R E E +R++EE + K E+ K EE+E +++ E E R+ +
Sbjct: 812 ERQQQEEALRRLEERR--REEEERRKQEELLRKQEEEAAKWAREEEEAQRRLE-ENRLRM 868
Query: 63 EETKEQILKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQSDLTTLTSAAYQQSL 120
EE ++ EE + ++ +L +Q +K E ++R+++Q L L QQ L
Sbjct: 869 EEEAARLRHEEE-----ERKRKELEVQRQK---ELMRQRQQQQEALRRLQQQQQQQQL 918
Score = 37.4 bits (85), Expect = 0.018
Identities = 28/82 (34%), Positives = 44/82 (53%), Gaps = 11/82 (13%)
Query: 27 ERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKHQL 86
E+ +Q E+ +EQ+ + E E R K+E EER EE + Q +E++L Q+E+
Sbjct: 724 EQLQQLEKAKAAKLEQE-RREAEMRAKREEEERKRQEELRRQ----QEEILRRQQEEE-- 776
Query: 87 FLQLKKVLHEEEKRRRKEQSDL 108
+K EEE RRK++ L
Sbjct: 777 ----RKRREEEELARRKQEEAL 794
Score = 35.8 bits (81), Expect = 0.053
Identities = 28/127 (22%), Positives = 60/127 (47%), Gaps = 25/127 (19%)
Query: 5 LERPKLSNAMARALHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEE 64
LE +L A RH ER+RK E + ++M Q+ ++++ R+ ++ +++ L +
Sbjct: 861 LEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQ 920
Query: 65 TK------------------------EQILKLEEKL-LALQEEKHQLFLQLKKVLHEEEK 99
K +I KLEE+ L+EE+ + +L K L ++++
Sbjct: 921 MKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQ 980
Query: 100 RRRKEQS 106
+++++ S
Sbjct: 981 QQQQKLS 987
Score = 34.7 bits (78), Expect = 0.12
Identities = 23/71 (32%), Positives = 41/71 (57%), Gaps = 3/71 (4%)
Query: 25 ERERKRQEEEEVDKMMEQ--KMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEE 82
E E +R+ EE +M E+ +++ E+E RK+KE+E + +E Q + +E L LQ++
Sbjct: 854 EEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQ-KELMRQRQQQQEALRRLQQQ 912
Query: 83 KHQLFLQLKKV 93
+ Q L K+
Sbjct: 913 QQQQQLAQMKL 923
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 59.7 bits (143), Expect = 3e-09
Identities = 34/103 (33%), Positives = 62/103 (60%), Gaps = 4/103 (3%)
Query: 5 LERPKLSNAMARALHRHIMMERERK---RQEEEEVDKMMEQKMKEEQERRKKKEMEERMS 61
L R K A+ R + I + R+R+ RQ++EE + +E++ +EE+ERRK++E+ +
Sbjct: 785 LARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQE 844
Query: 62 LEETKEQILKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKE 104
EE + + EE L+E + ++ + ++ HEEE+R+RKE
Sbjct: 845 -EEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKE 886
Score = 47.4 bits (111), Expect = 2e-05
Identities = 33/120 (27%), Positives = 63/120 (52%), Gaps = 18/120 (15%)
Query: 2 PALLERPKLSNAMARALH--------RHIMMERERKRQEEEEVDKMMEQKMKEEQERRKK 53
PAL + +L A A L R E ERKRQEE + + E+ ++ +QE +K
Sbjct: 721 PALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEE--LRRQQEEILRRQQEEERK 778
Query: 54 KEMEERMSLEETKEQILKLEEKLLALQ--------EEKHQLFLQLKKVLHEEEKRRRKEQ 105
+ EE ++ + +E + + E+ +AL+ +++ + +L++ EEE+RR++E+
Sbjct: 779 RREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEE 838
Score = 38.1 bits (87), Expect = 0.011
Identities = 34/118 (28%), Positives = 60/118 (50%), Gaps = 14/118 (11%)
Query: 6 ERPKLSNAMARALHRHIMMERERKRQEEEEVDKMMEQKMK---EEQERRKKKEMEERMSL 62
ER + A+ R R E E +R++EE + K E+ K EE+E +++ E E R+ +
Sbjct: 812 ERQQQEEALRRLEERR--REEEERRKQEELLRKQEEEAAKWAREEEEAQRRLE-ENRLRM 868
Query: 63 EETKEQILKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQSDLTTLTSAAYQQSL 120
EE ++ EE + ++ +L +Q +K E ++R+++Q L L QQ L
Sbjct: 869 EEEAARLRHEEE-----ERKRKELEVQRQK---ELMRQRQQQQEALRRLQQQQQQQQL 918
Score = 37.4 bits (85), Expect = 0.018
Identities = 28/82 (34%), Positives = 44/82 (53%), Gaps = 11/82 (13%)
Query: 27 ERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKHQL 86
E+ +Q E+ +EQ+ + E E R K+E EER EE + Q +E++L Q+E+
Sbjct: 724 EQLQQLEKAKAAKLEQE-RREAEMRAKREEEERKRQEELRRQ----QEEILRRQQEEE-- 776
Query: 87 FLQLKKVLHEEEKRRRKEQSDL 108
+K EEE RRK++ L
Sbjct: 777 ----RKRREEEELARRKQEEAL 794
Score = 35.8 bits (81), Expect = 0.053
Identities = 28/127 (22%), Positives = 60/127 (47%), Gaps = 25/127 (19%)
Query: 5 LERPKLSNAMARALHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEE 64
LE +L A RH ER+RK E + ++M Q+ ++++ R+ ++ +++ L +
Sbjct: 861 LEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQ 920
Query: 65 TK------------------------EQILKLEEKL-LALQEEKHQLFLQLKKVLHEEEK 99
K +I KLEE+ L+EE+ + +L K L ++++
Sbjct: 921 MKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQ 980
Query: 100 RRRKEQS 106
+++++ S
Sbjct: 981 QQQQKLS 987
Score = 34.7 bits (78), Expect = 0.12
Identities = 23/71 (32%), Positives = 41/71 (57%), Gaps = 3/71 (4%)
Query: 25 ERERKRQEEEEVDKMMEQ--KMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEE 82
E E +R+ EE +M E+ +++ E+E RK+KE+E + +E Q + +E L LQ++
Sbjct: 854 EEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQ-KELMRQRQQQQEALRRLQQQ 912
Query: 83 KHQLFLQLKKV 93
+ Q L K+
Sbjct: 913 QQQQQLAQMKL 923
>gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens]
Length = 1303
Score = 59.3 bits (142), Expect = 5e-09
Identities = 53/200 (26%), Positives = 96/200 (48%), Gaps = 10/200 (5%)
Query: 20 RHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLAL 79
+H++ +R+R+ +E++E + +E++ + E+E+RK +E E++ LE+ Q L+ EE+
Sbjct: 388 KHLLHQRQRRIEEQKEERRRVEEQQRREREQRKLQEKEQQRRLEDM--QALRREEERRQA 445
Query: 80 QEEKHQLFLQLKKVLHEEEKRR--RKEQSDLTTLTSAAYQQSLTVHTGTHLLSMQGSPGG 137
+ E+ QL++ E +R ++E + L +L QQ L LL P
Sbjct: 446 EREQEYKRKQLEEQRQSERLQRQLQQEHAYLKSLQQQQQQQQLQKQQQQQLLPGDRKPLY 505
Query: 138 HNRPGTLMAADR---AKQMFGPQVLTTRHYVGSAAAFAGT--PEHGQFQGSPGGAYGTAQ 192
H G + AD+ A+++ + + A + G+ PE Q SPG +Q
Sbjct: 506 HYGRG-MNPADKPAWAREVEERTRMNKQQNSPLAKSKPGSTGPEPPIPQASPGPPGPLSQ 564
Query: 193 PPPHYGPTQPAYSPSQQLRA 212
PP P +P P + L A
Sbjct: 565 TPPMQRPVEPQEGPHKSLVA 584
>gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens]
Length = 1332
Score = 59.3 bits (142), Expect = 5e-09
Identities = 53/200 (26%), Positives = 96/200 (48%), Gaps = 10/200 (5%)
Query: 20 RHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLAL 79
+H++ +R+R+ +E++E + +E++ + E+E+RK +E E++ LE+ Q L+ EE+
Sbjct: 388 KHLLHQRQRRIEEQKEERRRVEEQQRREREQRKLQEKEQQRRLEDM--QALRREEERRQA 445
Query: 80 QEEKHQLFLQLKKVLHEEEKRR--RKEQSDLTTLTSAAYQQSLTVHTGTHLLSMQGSPGG 137
+ E+ QL++ E +R ++E + L +L QQ L LL P
Sbjct: 446 EREQEYKRKQLEEQRQSERLQRQLQQEHAYLKSLQQQQQQQQLQKQQQQQLLPGDRKPLY 505
Query: 138 HNRPGTLMAADR---AKQMFGPQVLTTRHYVGSAAAFAGT--PEHGQFQGSPGGAYGTAQ 192
H G + AD+ A+++ + + A + G+ PE Q SPG +Q
Sbjct: 506 HYGRG-MNPADKPAWAREVEERTRMNKQQNSPLAKSKPGSTGPEPPIPQASPGPPGPLSQ 564
Query: 193 PPPHYGPTQPAYSPSQQLRA 212
PP P +P P + L A
Sbjct: 565 TPPMQRPVEPQEGPHKSLVA 584
>gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens]
Length = 1295
Score = 59.3 bits (142), Expect = 5e-09
Identities = 53/200 (26%), Positives = 96/200 (48%), Gaps = 10/200 (5%)
Query: 20 RHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLAL 79
+H++ +R+R+ +E++E + +E++ + E+E+RK +E E++ LE+ Q L+ EE+
Sbjct: 388 KHLLHQRQRRIEEQKEERRRVEEQQRREREQRKLQEKEQQRRLEDM--QALRREEERRQA 445
Query: 80 QEEKHQLFLQLKKVLHEEEKRR--RKEQSDLTTLTSAAYQQSLTVHTGTHLLSMQGSPGG 137
+ E+ QL++ E +R ++E + L +L QQ L LL P
Sbjct: 446 EREQEYKRKQLEEQRQSERLQRQLQQEHAYLKSLQQQQQQQQLQKQQQQQLLPGDRKPLY 505
Query: 138 HNRPGTLMAADR---AKQMFGPQVLTTRHYVGSAAAFAGT--PEHGQFQGSPGGAYGTAQ 192
H G + AD+ A+++ + + A + G+ PE Q SPG +Q
Sbjct: 506 HYGRG-MNPADKPAWAREVEERTRMNKQQNSPLAKSKPGSTGPEPPIPQASPGPPGPLSQ 564
Query: 193 PPPHYGPTQPAYSPSQQLRA 212
PP P +P P + L A
Sbjct: 565 TPPMQRPVEPQEGPHKSLVA 584
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 55.8 bits (133), Expect = 5e-08
Identities = 31/91 (34%), Positives = 61/91 (67%), Gaps = 10/91 (10%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQERRKKKEME----ERMSLEETKEQILKLEEKLLALQ 80
ERER+ +EEEE+ + EQ ++EE+E+R+++E+E E +++ +EQ+L+ E + Q
Sbjct: 1105 ERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQ 1164
Query: 81 E------EKHQLFLQLKKVLHEEEKRRRKEQ 105
E E+ +L + +++L EE+++RR+E+
Sbjct: 1165 ELERQYREEEELQQEEEQLLREEQEKRRQER 1195
Score = 55.1 bits (131), Expect = 9e-08
Identities = 31/91 (34%), Positives = 60/91 (65%), Gaps = 10/91 (10%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQERRKKKEME----ERMSLEETKEQILKLEEKLLALQ 80
ERE+K +EEEE+ + EQ ++EE+E+R+++E E ++ L++ +EQ+L+ E + LQ
Sbjct: 985 EREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQ 1044
Query: 81 E------EKHQLFLQLKKVLHEEEKRRRKEQ 105
E E+ +L + +++L EE + RR+++
Sbjct: 1045 ERERQYREEEELQQEEEQLLGEERETRRRQE 1075
Score = 53.1 bits (126), Expect = 3e-07
Identities = 34/93 (36%), Positives = 59/93 (63%), Gaps = 11/93 (11%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERM----SLEETKEQILKLEEKLLA 78
+ ERER+ +EEEE+ + EQ + EE+E R+++E+E + L++ +EQ+L+ E +
Sbjct: 1043 LQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRR 1102
Query: 79 LQE------EKHQLFLQLKKVLHEE-EKRRRKE 104
QE E+ +L + +++L EE EKRRR+E
Sbjct: 1103 RQERERQCREEEELQQEEEQLLREEREKRRRQE 1135
Score = 49.7 bits (117), Expect = 4e-06
Identities = 27/100 (27%), Positives = 53/100 (53%)
Query: 6 ERPKLSNAMARALHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEET 65
ER + R E R++Q E ++ EQ+++ EQE ++++ R EE
Sbjct: 313 ERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEER 372
Query: 66 KEQILKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
+EQ L+ E++L Q+ + + L+ ++ L E++ RR++Q
Sbjct: 373 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 412
Score = 49.7 bits (117), Expect = 4e-06
Identities = 32/91 (35%), Positives = 58/91 (63%), Gaps = 11/91 (12%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERM----SLEETKEQILKLEEKLLALQ 80
E+ER+ +EEE++ + EQ ++EE+E+R+++E E + L++ +EQ+L E + Q
Sbjct: 925 EQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQ 984
Query: 81 E------EKHQLFLQLKKVLHEE-EKRRRKE 104
E E+ +L + +++L EE EKRRR+E
Sbjct: 985 EREKKYREEEELQQEEEQLLREEREKRRRQE 1015
Score = 49.3 bits (116), Expect = 5e-06
Identities = 32/91 (35%), Positives = 57/91 (62%), Gaps = 11/91 (12%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQERRKKKEME----ERMSLEETKEQILKLEEKLLALQ 80
E ER+ ++EEE+ + EQ ++EE E+R+++E E E L++ +EQ+L+ E + Q
Sbjct: 1075 ELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQ 1134
Query: 81 E------EKHQLFLQLKKVLHEE-EKRRRKE 104
E E+ ++ + +++L EE EKRRR+E
Sbjct: 1135 ELERQYREEEEVQQEEEQLLREEPEKRRRQE 1165
Score = 49.3 bits (116), Expect = 5e-06
Identities = 30/81 (37%), Positives = 52/81 (64%), Gaps = 4/81 (4%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKH 84
E ER+ +EEEEV + EQ ++EE E+R+++E+E + EE +Q EE+LL ++EK
Sbjct: 1135 ELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQE---EEQLLREEQEKR 1191
Query: 85 QLFLQLKKVLHEEEKRRRKEQ 105
+ + ++ EEE +R+K +
Sbjct: 1192 RQERE-RQYREEEELQRQKRK 1211
Score = 48.9 bits (115), Expect = 6e-06
Identities = 25/89 (28%), Positives = 51/89 (57%)
Query: 19 HRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLA 78
H E+ KR++EE D + ++ E E+ ++K+ +R EE +E+ LKLEE+
Sbjct: 438 HEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERR 497
Query: 79 LQEEKHQLFLQLKKVLHEEEKRRRKEQSD 107
Q+E+ + L+ ++ E++ +R+E+ +
Sbjct: 498 EQQERREQQLRREQEERREQRLKRQEEEE 526
Score = 48.1 bits (113), Expect = 1e-05
Identities = 31/94 (32%), Positives = 54/94 (57%), Gaps = 15/94 (15%)
Query: 25 ERERKRQEEEEVDKMM-------EQKMKEEQE----RRKKKEMEERMSLEETKEQILKLE 73
E+ KR++EE D+++ +Q++K EQE +R K+E ER+ EE +EQ LK E
Sbjct: 564 EQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKRE 623
Query: 74 EKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQSD 107
E +EE+ Q L+ ++ +++ R+EQ +
Sbjct: 624 EP----EEERRQQLLKSEEQEERRQQQLRREQQE 653
Score = 47.8 bits (112), Expect = 1e-05
Identities = 24/85 (28%), Positives = 52/85 (61%), Gaps = 1/85 (1%)
Query: 24 MERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKE-QILKLEEKLLALQEE 82
+ RER+ +E+++ EQ+++ +QE ++++ EER +E +E Q + E++L QEE
Sbjct: 286 LRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEE 345
Query: 83 KHQLFLQLKKVLHEEEKRRRKEQSD 107
+ + L+ ++ E++ R+EQ +
Sbjct: 346 RREQQLRREQEEERREQQLRREQEE 370
Score = 47.0 bits (110), Expect = 2e-05
Identities = 30/110 (27%), Positives = 61/110 (55%), Gaps = 6/110 (5%)
Query: 2 PALLERPKLSNAMARALHRHIMME-RERKRQEEEEVDKMMEQKMKEEQER-----RKKKE 55
PAL E+ + + + + E RE++R++E+E E+++++E+E+ R+K+
Sbjct: 893 PALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRR 952
Query: 56 MEERMSLEETKEQILKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
+ER +++ + EE+LL + EK + + KK EEE ++ +EQ
Sbjct: 953 RQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQ 1002
Score = 46.2 bits (108), Expect = 4e-05
Identities = 26/88 (29%), Positives = 52/88 (59%), Gaps = 10/88 (11%)
Query: 20 RHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLAL 79
R + +E E +R+++E ++ + ++ +E +E+R K++ EE E +Q L+ E++L
Sbjct: 487 RWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEE-----ERLQQRLRSEQQLRRE 541
Query: 80 QEEKHQLFLQLKKVLHEEEKRRRKEQSD 107
QEE+ + L+ EEEKR +E+ +
Sbjct: 542 QEERREQLLK-----REEEKRLEQERRE 564
Score = 46.2 bits (108), Expect = 4e-05
Identities = 27/80 (33%), Positives = 51/80 (63%), Gaps = 1/80 (1%)
Query: 26 RERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKHQ 85
R+RK QEE+++ + ++ + QE +K EE++ L+E +EQ L+ +E+ +EE+ +
Sbjct: 1310 RDRKSQEEKQLLREEREEKRRRQETDRKFREEEQL-LQEREEQPLRRQERDRKFREEELR 1368
Query: 86 LFLQLKKVLHEEEKRRRKEQ 105
Q +K L EE++ RR+E+
Sbjct: 1369 HQEQGRKFLEEEQRLRRQER 1388
Score = 45.8 bits (107), Expect = 5e-05
Identities = 29/110 (26%), Positives = 60/110 (54%), Gaps = 7/110 (6%)
Query: 5 LERPKLSNAMARALHRHIMMERERK----RQEEEEVDKMMEQKMKEEQERRKKKEMEERM 60
L R +L + RER+ ++EEE+ + E +++E+E+ +++E + +
Sbjct: 210 LRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQR 269
Query: 61 SLEETKEQILKLEEKLL---ALQEEKHQLFLQLKKVLHEEEKRRRKEQSD 107
L+E +EQ+ KLE + L +EE+ Q L+ ++ L +++ R+EQ +
Sbjct: 270 ELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQE 319
Score = 45.8 bits (107), Expect = 5e-05
Identities = 30/90 (33%), Positives = 54/90 (60%), Gaps = 5/90 (5%)
Query: 16 RALHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEK 75
R R +ER+ + EEEEV + EQ ++EE E+R+++E+E + EE +Q EE+
Sbjct: 1128 REKRRRQELERQYR--EEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQ---EEEQ 1182
Query: 76 LLALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
LL ++EK + + + EE +R++++Q
Sbjct: 1183 LLREEQEKRRQERERQYREEEELQRQKRKQ 1212
Score = 45.8 bits (107), Expect = 5e-05
Identities = 33/89 (37%), Positives = 53/89 (59%), Gaps = 6/89 (6%)
Query: 18 LHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLL 77
LHR ER+RK EEE + E++ + +R +K EE++ L+E +EQ L+ +E+
Sbjct: 1636 LHRQ---ERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQL-LQEGEEQQLRRQERDR 1691
Query: 78 ALQEEKHQLFLQ--LKKVLHEEEKRRRKE 104
+EE+ QL Q +K L EE++ RR+E
Sbjct: 1692 KFREEEQQLRRQERERKFLQEEQQLRRQE 1720
Score = 45.4 bits (106), Expect = 7e-05
Identities = 24/86 (27%), Positives = 54/86 (62%), Gaps = 2/86 (2%)
Query: 20 RHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLAL 79
R + RE++ + E+++ + E++ +E+Q RR+++E ER + +EQ L+ E++L
Sbjct: 335 REQQLRREQEERREQQLRREQEEERREQQLRREQEE--ERREQQLRREQQLRREQQLRRE 392
Query: 80 QEEKHQLFLQLKKVLHEEEKRRRKEQ 105
Q+ + + L+ ++ L E++ RR++Q
Sbjct: 393 QQLRREQQLRREQQLRREQQLRREQQ 418
Score = 45.4 bits (106), Expect = 7e-05
Identities = 26/87 (29%), Positives = 50/87 (57%), Gaps = 2/87 (2%)
Query: 22 IMMERERKRQEEEEVD-KMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQ 80
++ ERE + +E D K E++++ +++ RK E E+R+ +E + + LK EE+ L Q
Sbjct: 1344 LLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLK-EEQQLRCQ 1402
Query: 81 EEKHQLFLQLKKVLHEEEKRRRKEQSD 107
E + QL + EEE++ +++ D
Sbjct: 1403 EREQQLRQDRDRKFREEEQQLSRQERD 1429
Score = 45.1 bits (105), Expect = 9e-05
Identities = 29/90 (32%), Positives = 55/90 (61%), Gaps = 12/90 (13%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSL------EETKEQILKLE----- 73
ER +R + EEV+++ +++ +E++ +R++ E E R L EE ++Q L+ E
Sbjct: 596 ERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERR 655
Query: 74 EKLLALQEEKHQLFLQLKKVLHEEEKRRRK 103
E+ L +EE+ +L +LK+ HEEE+R ++
Sbjct: 656 EQRLKREEEEERLEQRLKRE-HEEERREQE 684
Score = 45.1 bits (105), Expect = 9e-05
Identities = 31/101 (30%), Positives = 59/101 (58%), Gaps = 18/101 (17%)
Query: 25 ERERKRQEEEE----VDKMMEQK----MKEEQERRKKKEME----ERMSLEETKEQILKL 72
ERE++R++E E DK ++QK + EE E+R+++E E E L++ +EQ+L+
Sbjct: 947 EREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLRE 1006
Query: 73 EEKLLALQE------EKHQLFLQLKKVLHEEEKRRRKEQSD 107
E + QE +K +L + +++L EE ++RR ++ +
Sbjct: 1007 EREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERE 1047
Score = 44.3 bits (103), Expect = 2e-04
Identities = 27/94 (28%), Positives = 55/94 (58%), Gaps = 6/94 (6%)
Query: 18 LHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSL----EETK--EQILK 71
L R + RE++ + E+E ++ ++ +E +E+R K+E EER EET+ EQ +
Sbjct: 413 LRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERR 472
Query: 72 LEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
++ +EE+ + +L+L++ E++ RR++Q
Sbjct: 473 KQQLKRDQEEERRERWLKLEEEERREQQERREQQ 506
Score = 44.3 bits (103), Expect = 2e-04
Identities = 26/86 (30%), Positives = 53/86 (61%), Gaps = 11/86 (12%)
Query: 25 ERERKRQ------EEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLA 78
E+ER++Q EEE ++ ++ + +E +E+++++E + R EE +EQ LK +E
Sbjct: 468 EQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQE---- 523
Query: 79 LQEEKHQLFLQLKKVLHEEEKRRRKE 104
+EE+ Q L+ ++ L E++ RR++
Sbjct: 524 -EEERLQQRLRSEQQLRREQEERREQ 548
Score = 44.3 bits (103), Expect = 2e-04
Identities = 30/95 (31%), Positives = 60/95 (63%), Gaps = 10/95 (10%)
Query: 20 RHIMMERERK-RQEEEEVDKM-MEQKMKEEQER-----RKKKEMEERMSLEETKEQILKL 72
+ + +R+RK R+EE+++ + ++K +EE+++ R++K +EE L + + + +
Sbjct: 1406 QQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFRE 1465
Query: 73 EEKLLALQEEKHQLFLQL--KKVLHEEEKRRRKEQ 105
EE+LL +EE+ QL Q +K L EE++ RR+E+
Sbjct: 1466 EEQLLQEREEQ-QLHRQERDRKFLEEEQQLRRQER 1499
Score = 44.3 bits (103), Expect = 2e-04
Identities = 32/93 (34%), Positives = 53/93 (56%), Gaps = 7/93 (7%)
Query: 20 RHIMMERERKRQEEEEVDKMMEQKMKEEQER-RKKKEMEERMSLEET----KEQILKLEE 74
+ + ER RK +EEE++ + E++ QER RK E E+++ +E +EQ L+ +E
Sbjct: 1453 QQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQE 1512
Query: 75 KLLALQEEKHQLFLQ--LKKVLHEEEKRRRKEQ 105
EE+ QL Q +K L EE++ RR+E+
Sbjct: 1513 PERKFLEEEQQLHRQQRQRKFLQEEQQLRRQER 1545
Score = 43.9 bits (102), Expect = 2e-04
Identities = 34/122 (27%), Positives = 63/122 (51%), Gaps = 20/122 (16%)
Query: 4 LLERPKLSNAMARALHRHIMMERERK-RQEEEEVDKMMEQKMKEEQERRKKKEMEERMSL 62
L E P+L RH +R+RK R+EE+ + + EQ+++ ++ RK +E E+++
Sbjct: 1646 LEEEPQLRRQEREQQLRH---DRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRR 1702
Query: 63 EETKEQILKLEEKL--------------LALQEEKHQLFLQ--LKKVLHEEEKRRRKEQS 106
+E + + L+ E++L L + E+ QL Q +K+L EE+ R +E+
Sbjct: 1703 QERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQ 1762
Query: 107 DL 108
L
Sbjct: 1763 QL 1764
Score = 43.5 bits (101), Expect = 3e-04
Identities = 32/91 (35%), Positives = 53/91 (58%), Gaps = 11/91 (12%)
Query: 25 ERERKRQEEEEVDKMM---EQKMKEEQERRKK---KEMEERMSLEETKEQILKLE----- 73
E+ KRQEEEE + EQ+++ EQE R++ K EE+ +E +EQ LK E
Sbjct: 516 EQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERR 575
Query: 74 EKLLALQEEKHQLFLQLKKVLHEEEKRRRKE 104
++LL +EE+ Q L+ ++ E++ +R+E
Sbjct: 576 DQLLKREEERRQQRLKREQEERLEQRLKREE 606
Score = 43.5 bits (101), Expect = 3e-04
Identities = 29/97 (29%), Positives = 58/97 (59%), Gaps = 14/97 (14%)
Query: 20 RHIMMERERKRQEEE---EVDKMMEQKMKEEQERRKKKE--MEERMSLEETKE----QIL 70
R +++RE +R+++ E ++ +EQ++K E+ R ++E E+R+ EE +E Q+L
Sbjct: 575 RDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLL 634
Query: 71 KLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQSD 107
K EE QEE+ Q L+ ++ E++ +R+E+ +
Sbjct: 635 KSEE-----QEERRQQQLRREQQERREQRLKREEEEE 666
Score = 43.5 bits (101), Expect = 3e-04
Identities = 26/88 (29%), Positives = 52/88 (59%), Gaps = 4/88 (4%)
Query: 18 LHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLE-EKL 76
LHR +R+RK +EE+ + E+ + Q+R +K EE++ E ++Q+ + E ++
Sbjct: 1524 LHRQ---QRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRK 1580
Query: 77 LALQEEKHQLFLQLKKVLHEEEKRRRKE 104
L+E+K + Q +K + +E++ RR+E
Sbjct: 1581 FRLEEQKVRRQEQERKFMEDEQQLRRQE 1608
Score = 43.1 bits (100), Expect = 3e-04
Identities = 29/102 (28%), Positives = 59/102 (57%), Gaps = 7/102 (6%)
Query: 5 LERPKLSNAMARALHRHIMMERERK-RQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLE 63
LER +L + + RE++ R+++EE + +++ +E+QERR ++ EER +
Sbjct: 281 LERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERR--EQQEERREQQ 338
Query: 64 ETKEQILKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
+EQ + E++L QEE+ + +++ E+E+ RR++Q
Sbjct: 339 LRREQEERREQQLRREQEEER----REQQLRREQEEERREQQ 376
Score = 43.1 bits (100), Expect = 3e-04
Identities = 27/95 (28%), Positives = 51/95 (53%), Gaps = 9/95 (9%)
Query: 20 RHIMMERERKRQEEEEVDKMMEQKMKEEQERR----KKKEMEERMSLEETKEQILKLEE- 74
+ + E+E +R E++ + EQ++K EQE R K++E ER E K+Q+ + +E
Sbjct: 423 QQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEE 482
Query: 75 ----KLLALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
+ L L+EE+ + + ++ E+ R+EQ
Sbjct: 483 ERRERWLKLEEEERREQQERREQQLRREQEERREQ 517
Score = 43.1 bits (100), Expect = 3e-04
Identities = 24/78 (30%), Positives = 49/78 (62%), Gaps = 7/78 (8%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQ-ERRKKKEMEERMSLEETKEQILKLEEKLLALQEEK 83
E++ +R++EE ++ ++++ +EE+ ++R + E + R EE +EQ+LK EE+ QE +
Sbjct: 504 EQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERR 563
Query: 84 HQLFLQLKKVLHEEEKRR 101
Q ++ E+E+RR
Sbjct: 564 EQ------RLKREQEERR 575
Score = 42.7 bits (99), Expect = 4e-04
Identities = 23/87 (26%), Positives = 53/87 (60%), Gaps = 4/87 (4%)
Query: 20 RHIMMERERKRQEEEEVDKMMEQKMKEEQERR-KKKEMEERMSLEETKEQILKLEEKLLA 78
R ++ +E ++ +EEE + E + +EEQ R+ +++E+ EE ++Q L+ E++L
Sbjct: 249 RETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRR 308
Query: 79 LQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
QEE+ + + ++ E+++RR +++
Sbjct: 309 KQEEERR---EQQEERREQQERREQQE 332
Score = 42.7 bits (99), Expect = 4e-04
Identities = 25/83 (30%), Positives = 48/83 (57%), Gaps = 2/83 (2%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKH 84
+R+RK +EEE++ + E++ QER +K +EE+ + +E+ +E+ L QE +
Sbjct: 1552 DRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQ 1611
Query: 85 QLFLQLKKVLHEEEK--RRRKEQ 105
QL + + E+E+ + R+EQ
Sbjct: 1612 QLRQERDRKFREDEQLLQEREEQ 1634
Score = 42.7 bits (99), Expect = 4e-04
Identities = 26/89 (29%), Positives = 52/89 (58%), Gaps = 8/89 (8%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILK------LEEKLLA 78
E++ RQE + ++ EQK++ +++ RK E E+++ +E ++Q+ + E++ L
Sbjct: 1569 EQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLL 1628
Query: 79 LQEEKHQLFLQL--KKVLHEEEKRRRKEQ 105
+ E+ QL Q +K L EE + RR+E+
Sbjct: 1629 QEREEQQLHRQERDRKFLEEEPQLRRQER 1657
Score = 42.4 bits (98), Expect = 6e-04
Identities = 23/88 (26%), Positives = 49/88 (55%), Gaps = 2/88 (2%)
Query: 18 LHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLL 77
L R ER ++ E+ ++ EQ+++ EQ+ R+++++ L +EQ L+ E++L
Sbjct: 351 LRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLR--REQQLRREQQLR 408
Query: 78 ALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
Q+ + + L+ ++ L E++ R EQ
Sbjct: 409 REQQLRREQQLRREQQLRREQEEERHEQ 436
Score = 42.4 bits (98), Expect = 6e-04
Identities = 29/107 (27%), Positives = 62/107 (57%), Gaps = 12/107 (11%)
Query: 5 LERPKLSNAMARALHRHIMMERERKRQEEEEVDKMMEQKMKEE-QERRKKKEMEERMSLE 63
L+R + + + L + RE++ + E+ + + E+++++E +E+R K+E EER
Sbjct: 519 LKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEER---- 574
Query: 64 ETKEQILKLEE-----KLLALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
++Q+LK EE +L QEE+ + L+ ++V E++ RR+++
Sbjct: 575 --RDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQR 619
Score = 42.4 bits (98), Expect = 6e-04
Identities = 26/85 (30%), Positives = 51/85 (60%), Gaps = 3/85 (3%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQER-RKKKEMEERMSLEETKEQILKLEEKLLALQEEK 83
ERERK +EE+ + E++ + Q+R RK +E E+++S +E + EE+ ++E+
Sbjct: 1387 ERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKF--REEEQQVRRQER 1444
Query: 84 HQLFLQLKKVLHEEEKRRRKEQSDL 108
+ FL+ ++ L +E R+ +E+ L
Sbjct: 1445 ERKFLEEEQQLRQERHRKFREEEQL 1469
Score = 42.4 bits (98), Expect = 6e-04
Identities = 30/93 (32%), Positives = 50/93 (53%), Gaps = 9/93 (9%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILK-------LEEKLL 77
E ERK +EEE++ + EQ+ QER +K EE++ E ++Q+ + EE+ L
Sbjct: 1720 ELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQL 1779
Query: 78 ALQEEKHQLFLQL--KKVLHEEEKRRRKEQSDL 108
+ E+ QL Q +K EE+ R+ +E+ L
Sbjct: 1780 RQEREEQQLRSQESDRKFREEEQLRQEREEQQL 1812
Score = 42.0 bits (97), Expect = 7e-04
Identities = 22/94 (23%), Positives = 53/94 (56%), Gaps = 4/94 (4%)
Query: 18 LHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEET----KEQILKLE 73
L R RE++ + E+E ++ +Q +E++E R+++++ L +EQ L+ E
Sbjct: 339 LRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRRE 398
Query: 74 EKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQSD 107
++L Q+ + + L+ ++ L E++ RR+++ +
Sbjct: 399 QQLRREQQLRREQQLRREQQLRREQQLRREQEEE 432
Score = 42.0 bits (97), Expect = 7e-04
Identities = 27/98 (27%), Positives = 56/98 (57%), Gaps = 3/98 (3%)
Query: 6 ERPKLSNAMARALHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEET 65
ER + + L R RE++ + +EE +++ ++ E+Q RR+++E E++ L+
Sbjct: 495 ERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQL-LKRE 553
Query: 66 KEQILKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRK 103
+E+ L+ E + L+ E+ + QL K EEE+R+++
Sbjct: 554 EEKRLEQERREQRLKREQEERRDQLLK--REEERRQQR 589
Score = 42.0 bits (97), Expect = 7e-04
Identities = 34/93 (36%), Positives = 53/93 (56%), Gaps = 12/93 (12%)
Query: 25 ERERKRQEEEEVD-KMMEQKMKEEQERRK----KKEMEERM-----SLEETKEQILKLEE 74
E+ KR+EE+ ++ + EQ++K EQE R+ K+E E R EE EQ LK EE
Sbjct: 547 EQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREE 606
Query: 75 KLLALQEEKHQLFLQLKKVLHEEEKRRRKEQSD 107
QEE+ + +LK+ EEE+R++ +S+
Sbjct: 607 VERLEQEERRE--QRLKREEPEEERRQQLLKSE 637
Score = 41.6 bits (96), Expect = 0.001
Identities = 32/102 (31%), Positives = 50/102 (49%), Gaps = 17/102 (16%)
Query: 4 LLERPKLSNAMARALHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLE 63
L RP L R L +RE++ EEE ++EQ RR+++E E+ +
Sbjct: 784 LSARPPLREQRERQLRAEERQQREQRFLPEEE---------EKEQRRRQRREREKELQFL 834
Query: 64 ETKEQILKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
E +EQ L+ E+ LQEE+ L ++E+RR +EQ
Sbjct: 835 EEEEQ-LQRRERAQQLQEEEDGL-------QEDQERRRSQEQ 868
Score = 41.6 bits (96), Expect = 0.001
Identities = 24/84 (28%), Positives = 50/84 (59%), Gaps = 2/84 (2%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKH 84
ER+RK +EEE+ + E++ K +E ++ ++ R EE EQ+L+ E+ ++E+
Sbjct: 1427 ERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREE--EQLLQEREEQQLHRQERD 1484
Query: 85 QLFLQLKKVLHEEEKRRRKEQSDL 108
+ FL+ ++ L +E+ R+ + +L
Sbjct: 1485 RKFLEEEQQLRRQERDRKFREQEL 1508
Score = 41.6 bits (96), Expect = 0.001
Identities = 29/98 (29%), Positives = 55/98 (56%), Gaps = 3/98 (3%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEK--LLALQEE 82
ER+RK +EEE++ + E++ QE +K EE++ +E +EQ L+ +++ +EE
Sbjct: 1768 ERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLR-QEREEQQLRPQQRDGKYRWEEE 1826
Query: 83 KHQLFLQLKKVLHEEEKRRRKEQSDLTTLTSAAYQQSL 120
+ QL Q +++ E +++ R E+ T S +Q L
Sbjct: 1827 QLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQEL 1864
Score = 40.8 bits (94), Expect = 0.002
Identities = 28/98 (28%), Positives = 57/98 (58%), Gaps = 17/98 (17%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQERRK----------KKEMEERMSLEETKEQILKLEE 74
++ER+R +E+ D+ +++EE++RR+ ++ +E+ L+E +E++ + E
Sbjct: 859 DQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREER 918
Query: 75 KLLALQE------EKHQLFLQLKKVLHEE-EKRRRKEQ 105
+ QE E+ QL + +++L EE EKRRR+E+
Sbjct: 919 EKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQER 956
Score = 40.8 bits (94), Expect = 0.002
Identities = 25/93 (26%), Positives = 50/93 (53%), Gaps = 4/93 (4%)
Query: 16 RALHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEK 75
R R +R+R EEE+ +E++ ++E +RR +K EE+ L E +E+ + +E
Sbjct: 1279 REQERRRWQQRDRHFPEEEQ----LEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQET 1334
Query: 76 LLALQEEKHQLFLQLKKVLHEEEKRRRKEQSDL 108
+EE+ L + ++ L +E+ R+ + +L
Sbjct: 1335 DRKFREEEQLLQEREEQPLRRQERDRKFREEEL 1367
Score = 40.8 bits (94), Expect = 0.002
Identities = 23/85 (27%), Positives = 55/85 (64%), Gaps = 5/85 (5%)
Query: 25 ERERK-RQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEK 83
ERE++ RQ+ + + EQ++ ++ RK +E E+++ +E + + L+ E++L ++E+
Sbjct: 1403 EREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQL---RQER 1459
Query: 84 HQLFLQLKKVLHE-EEKRRRKEQSD 107
H+ F + +++L E EE++ +++ D
Sbjct: 1460 HRKFREEEQLLQEREEQQLHRQERD 1484
Score = 40.8 bits (94), Expect = 0.002
Identities = 34/106 (32%), Positives = 57/106 (53%), Gaps = 17/106 (16%)
Query: 25 ERERKRQEEEEVDKMMEQKMK---EEQERRK----KKEMEERMSLEETKEQILK------ 71
ER+RK +EEE+ + E++ K EEQ+ R+ +K EE +ET+++ L+
Sbjct: 1688 ERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYR 1747
Query: 72 --LEEKLLALQEEKHQLFLQL--KKVLHEEEKRRRKEQSDLTTLTS 113
LEE+ L + E+ QL Q +K EE+ R+ +E+ L + S
Sbjct: 1748 KILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQES 1793
Score = 40.4 bits (93), Expect = 0.002
Identities = 26/92 (28%), Positives = 55/92 (59%), Gaps = 9/92 (9%)
Query: 18 LHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEME--ERMSLEETKEQILKLEEK 75
L R + RE++ + E+++ + EQ+++ EQ+ R+++E E E+ +E +EQ LK E+
Sbjct: 395 LRREQQLRREQQLRREQQLRR--EQQLRREQQLRREQEEERHEQKHEQERREQRLKREQ- 451
Query: 76 LLALQEEKHQLFLQLKKVLHEEEKRRRKEQSD 107
+E + L + + HE+E+R+++ + D
Sbjct: 452 ----EERRDWLKREEETERHEQERRKQQLKRD 479
Score = 40.4 bits (93), Expect = 0.002
Identities = 32/105 (30%), Positives = 57/105 (54%), Gaps = 16/105 (15%)
Query: 20 RHIMMERERKRQEEEEVDKMMEQKMKEEQERRK---KKEMEERMSLEETKEQILKLE--- 73
R ++RE + + E+ + + K +E+ERR+ K E EER +E +EQ L+ E
Sbjct: 454 RRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEE 513
Query: 74 --EKLLALQEEKHQLFLQLK---KVLHEEEKR-----RRKEQSDL 108
E+ L QEE+ +L +L+ ++ E+E+R +R+E+ L
Sbjct: 514 RREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRL 558
Score = 40.4 bits (93), Expect = 0.002
Identities = 31/104 (29%), Positives = 57/104 (54%), Gaps = 20/104 (19%)
Query: 22 IMMERERKRQEEE---------EVDKMMEQKMKEEQERRKKKEME----ERMSLEETKEQ 68
++ E KR+ +E E+ + EQ ++EE+E+R+ +E E E L++ +EQ
Sbjct: 1003 LLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQ 1062
Query: 69 ILKLEEKLLALQE------EKHQLFLQLKKVLHEE-EKRRRKEQ 105
+L E + QE ++ +L + +++L EE EKRRR+E+
Sbjct: 1063 LLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQER 1106
Score = 40.0 bits (92), Expect = 0.003
Identities = 23/84 (27%), Positives = 45/84 (53%), Gaps = 5/84 (5%)
Query: 28 RKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKHQLF 87
R++QEEE+ Q EE+ R ++ + R L E +E+ L+ EE+ +++ Q F
Sbjct: 756 RQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEER-----QQREQRF 810
Query: 88 LQLKKVLHEEEKRRRKEQSDLTTL 111
L ++ + ++RR+ + +L L
Sbjct: 811 LPEEEEKEQRRRQRREREKELQFL 834
Score = 40.0 bits (92), Expect = 0.003
Identities = 28/111 (25%), Positives = 56/111 (50%), Gaps = 10/111 (9%)
Query: 6 ERPKLSNAMARALHRHIMMERERKRQEEEEV-------DKMMEQKMKEEQERRKKKEMEE 58
E L + LHR ER+RK EEE+ K EQ+++ ++ RK E E+
Sbjct: 1466 EEQLLQEREEQQLHRQ---ERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQ 1522
Query: 59 RMSLEETKEQILKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQSDLT 109
++ ++ + + L+ E++L + + + + +K EE+ R+ +E+ L+
Sbjct: 1523 QLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLS 1573
Score = 39.7 bits (91), Expect = 0.004
Identities = 28/104 (26%), Positives = 54/104 (51%), Gaps = 24/104 (23%)
Query: 23 MMERERKRQ-----EEEEVDKM--------------MEQKMKEEQERRKKKEMEERMSLE 63
+ E E +RQ EEE++ K+ +Q+++ EQ+ R+K+E E R E
Sbjct: 260 LQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQE 319
Query: 64 ETKEQILKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQSD 107
E +EQ + E+ QEE+ + L+ ++ E++ RR+++ +
Sbjct: 320 ERREQQERREQ-----QEERREQQLRREQEERREQQLRREQEEE 358
Score = 39.7 bits (91), Expect = 0.004
Identities = 26/97 (26%), Positives = 58/97 (59%), Gaps = 13/97 (13%)
Query: 20 RHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLAL 79
R + RE++ + E+++ + EQ+++ EQ+ R+++++ L +EQ L+ E++L
Sbjct: 373 REQQLRREQQLRREQQLRR--EQQLRREQQLRREQQLRREQQLR--REQQLRREQQLRRE 428
Query: 80 QEE-----KHQLFLQLKKVLHEEEKRR----RKEQSD 107
QEE KH+ + +++ E+E+RR R+E+++
Sbjct: 429 QEEERHEQKHEQERREQRLKREQEERRDWLKREEETE 465
Score = 39.7 bits (91), Expect = 0.004
Identities = 31/93 (33%), Positives = 49/93 (52%), Gaps = 11/93 (11%)
Query: 24 MERERKRQEEEEVDKMMEQK--MKEEQERRKKKEMEE----RMSLEETKEQILKLEEKLL 77
+E E + Q E ++ E++ ++E+QERR+ +E R LEE +++
Sbjct: 834 LEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKP 893
Query: 78 ALQEE--KHQLFLQLKK---VLHEEEKRRRKEQ 105
ALQE+ K Q LQ ++ E EKRRR+EQ
Sbjct: 894 ALQEQLRKEQQLLQEEEEELQREEREKRRRQEQ 926
Score = 39.7 bits (91), Expect = 0.004
Identities = 26/83 (31%), Positives = 50/83 (60%), Gaps = 3/83 (3%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKH 84
E+ERK E+E+ + E + + QER +K +E++ L+E +EQ L +E+ EE+
Sbjct: 1592 EQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQL-LQEREEQQLHRQERDRKFLEEEP 1650
Query: 85 QLFLQLK--KVLHEEEKRRRKEQ 105
QL Q + ++ H+ +++ R+E+
Sbjct: 1651 QLRRQEREQQLRHDRDRKFREEE 1673
Score = 38.9 bits (89), Expect = 0.006
Identities = 25/89 (28%), Positives = 50/89 (56%), Gaps = 4/89 (4%)
Query: 20 RHIMMERERKRQEEEEVDKMMEQKMKE---EQERRKKKEMEERMSLEETKEQILKLEEKL 76
R ERE +R EEE++ + +E E++ R+++ +E R E K+Q + E +
Sbjct: 177 RQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQ-QRRERQD 235
Query: 77 LALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
QEE+ + + + + VL +EE++ ++E+
Sbjct: 236 RVFQEEEEKEWRKRETVLRKEEEKLQEEE 264
Score = 38.9 bits (89), Expect = 0.006
Identities = 26/108 (24%), Positives = 60/108 (55%), Gaps = 7/108 (6%)
Query: 4 LLERPKLSNAMARALHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEM---EERM 60
LL+ + + L R RE++ + EEE +++ ++ +E +E R+++E+ E+
Sbjct: 633 LLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQ 692
Query: 61 SLEETKEQILKLEEKLLALQEEKH-QLFLQLKKVLHEEEKRRRKEQSD 107
+ E K +I K + +L + + + +++ + +K +E +RRR+EQ +
Sbjct: 693 ARERIKSRIPKWQWQLESEADARQSKVYSRPRK---QEGQRRRQEQEE 737
Score = 38.5 bits (88), Expect = 0.008
Identities = 26/86 (30%), Positives = 47/86 (54%), Gaps = 5/86 (5%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKH 84
E+ R+R+ E K E+K ++ +ER+ + EE +E +L+ EE+ L +E +
Sbjct: 208 EQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQR 267
Query: 85 QLFL-----QLKKVLHEEEKRRRKEQ 105
Q L QL+K+ +E +R R+E+
Sbjct: 268 QRELQEEEEQLRKLERQELRRERQEE 293
Score = 38.1 bits (87), Expect = 0.011
Identities = 27/106 (25%), Positives = 61/106 (57%), Gaps = 5/106 (4%)
Query: 5 LERPKLSNAMARALHRHIMMER-ERKRQEEEEVDKMMEQKMKEEQ--ERRKKKEMEERMS 61
LE +L + ++ +H++ E+ ER R++E + ++ EE+ ER ++KE + R
Sbjct: 1253 LEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDR 1312
Query: 62 LEETKEQILKLEEKLLALQEEKHQLFLQLKKVLHEEEKR--RRKEQ 105
+ ++Q+L+ E + ++E + F + +++L E E++ RR+E+
Sbjct: 1313 KSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQER 1358
Score = 38.1 bits (87), Expect = 0.011
Identities = 21/92 (22%), Positives = 53/92 (57%), Gaps = 6/92 (6%)
Query: 20 RHIMMERERKR--QEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLL 77
R + E ++ R + E+++ + ++K +EE+++ ++E + + EE + + + E K L
Sbjct: 1390 RKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFL 1449
Query: 78 ----ALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
L++E+H+ F + +++L E E+++ Q
Sbjct: 1450 EEEQQLRQERHRKFREEEQLLQEREEQQLHRQ 1481
Score = 37.4 bits (85), Expect = 0.018
Identities = 28/83 (33%), Positives = 46/83 (55%), Gaps = 8/83 (9%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKH 84
ER RK EEE++ E++ QER +K EE++ +E +EQ L+ +E +EE+
Sbjct: 1744 ERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLR-QEREEQQLRSQESDRKFREEE- 1801
Query: 85 QLFLQLKKVLHEEEKRRRKEQSD 107
QL++ EE++ R +Q D
Sbjct: 1802 ----QLRQ--EREEQQLRPQQRD 1818
Score = 37.0 bits (84), Expect = 0.024
Identities = 23/95 (24%), Positives = 49/95 (51%), Gaps = 2/95 (2%)
Query: 7 RPKLSNAMARALHRHIMMERE--RKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEE 64
RP+ + R + +E + R RQE + + EQ +E+ RR+++E+ + +
Sbjct: 1813 RPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKR 1872
Query: 65 TKEQILKLEEKLLALQEEKHQLFLQLKKVLHEEEK 99
+E+ KL E+ + Q+++ Q Q+ ++ +E K
Sbjct: 1873 RQERERKLREEHIRRQQKEEQRHRQVGEIKSQEGK 1907
Score = 36.6 bits (83), Expect = 0.031
Identities = 23/81 (28%), Positives = 47/81 (58%), Gaps = 4/81 (4%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKH 84
+R+ K + EEE ++ EQ+ + QER ++ EE+ + +E + EE+ L +EE+
Sbjct: 1816 QRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRR----EEQELWQEEEQK 1871
Query: 85 QLFLQLKKVLHEEEKRRRKEQ 105
+ + +K+ E +R++KE+
Sbjct: 1872 RRQERERKLREEHIRRQQKEE 1892
Score = 36.2 bits (82), Expect = 0.041
Identities = 31/110 (28%), Positives = 59/110 (53%), Gaps = 29/110 (26%)
Query: 24 MERERKR-----------QEEEEVDKMMEQKMKEE-----QERRKKKEME----ERMSLE 63
+E ERKR QE+ ++ + Q+ +EE +E+R+++E E E L+
Sbjct: 878 LEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQ 937
Query: 64 ETKEQILKLEEKLLALQEEKHQLFLQLKKVLHEE--------EKRRRKEQ 105
+ +EQ+L+ EE+ ++E+ + + + KK+ +E EKRRR+E+
Sbjct: 938 QEEEQLLR-EEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQER 986
Score = 35.8 bits (81), Expect = 0.053
Identities = 28/89 (31%), Positives = 47/89 (52%), Gaps = 8/89 (8%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILK------LEEKLLA 78
E+E + QE E EQ++ +Q +RK + E+++ +E +Q + EE+ L
Sbjct: 1505 EQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLR 1564
Query: 79 LQEEKHQLFLQL--KKVLHEEEKRRRKEQ 105
+ E+ QL Q +K EE+K RR+EQ
Sbjct: 1565 QEREEQQLSRQERDRKFRLEEQKVRRQEQ 1593
Score = 35.4 bits (80), Expect = 0.070
Identities = 20/91 (21%), Positives = 45/91 (49%)
Query: 15 ARALHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEE 74
AR + +++ R+ +++ + Q +E +RR++K E+ L E +EQ K E
Sbjct: 101 ARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQER 160
Query: 75 KLLALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
++ + + + ++ E E+RR +E+
Sbjct: 161 LEQRDRQRRDEELWRQRQEWQEREERRAEEE 191
Score = 35.4 bits (80), Expect = 0.070
Identities = 26/102 (25%), Positives = 49/102 (48%)
Query: 5 LERPKLSNAMARALHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEE 64
L+R + + L + E R++Q E + EQ++K E+E + ++ +R EE
Sbjct: 620 LKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEE 679
Query: 65 TKEQILKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQS 106
+EQ L EE+ A + K ++ ++ E + R+ K S
Sbjct: 680 RREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYS 721
Score = 35.4 bits (80), Expect = 0.070
Identities = 28/95 (29%), Positives = 50/95 (52%), Gaps = 16/95 (16%)
Query: 25 ERERKRQEEEEVDKMMEQK-----------MKEEQERRKKKEMEERMSLEE---TKEQIL 70
E E+ RQE EE +Q+ EEQE+R ++E + + EE T+E+
Sbjct: 1799 EEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSR 1858
Query: 71 KLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
+ E++L QEE+ + + ++ L EE RR++++
Sbjct: 1859 REEQEL--WQEEEQKRRQERERKLREEHIRRQQKE 1891
Score = 34.7 bits (78), Expect = 0.12
Identities = 24/89 (26%), Positives = 48/89 (53%), Gaps = 3/89 (3%)
Query: 19 HRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLA 78
+R I+ E + + + EE+ + E+ K +E + ++E EE+ + ++ + EE+ L
Sbjct: 1746 YRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFR-EEEQLR 1804
Query: 79 LQEEKHQLFLQLK--KVLHEEEKRRRKEQ 105
+ E+ QL Q + K EEE+ + +EQ
Sbjct: 1805 QEREEQQLRPQQRDGKYRWEEEQLQLEEQ 1833
Score = 34.3 bits (77), Expect = 0.16
Identities = 23/81 (28%), Positives = 44/81 (54%), Gaps = 8/81 (9%)
Query: 27 ERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKHQL 86
+R RQ +E Q+ +E +ERR ++E + ET+E EE+L + +
Sbjct: 163 QRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEE--FPDEEQL------RRRE 214
Query: 87 FLQLKKVLHEEEKRRRKEQSD 107
L+L++ EE++++R+E+ D
Sbjct: 215 LLELRRKGREEKQQQRRERQD 235
Score = 34.3 bits (77), Expect = 0.16
Identities = 24/86 (27%), Positives = 50/86 (58%), Gaps = 10/86 (11%)
Query: 25 ERERKRQEEEEVDKMMEQK-----MKEEQERRKKKEMEERMSLEETKEQILKLEEKLLAL 79
E E+ RQE EE +++ ++E++ RR++ +ER +E+ EQ L+ +E L
Sbjct: 1559 EEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQE---QERKFMED--EQQLRRQEGQQQL 1613
Query: 80 QEEKHQLFLQLKKVLHEEEKRRRKEQ 105
++E+ + F + +++L E E+++ Q
Sbjct: 1614 RQERDRKFREDEQLLQEREEQQLHRQ 1639
Score = 33.9 bits (76), Expect = 0.20
Identities = 26/96 (27%), Positives = 47/96 (48%), Gaps = 14/96 (14%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQE--- 81
ERERK EEE+ E+ K +E + +E EE+ + +++ EE+ L QE
Sbjct: 1443 ERERKFLEEEQ-QLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDR 1501
Query: 82 ----------EKHQLFLQLKKVLHEEEKRRRKEQSD 107
E + FL+ ++ LH ++++R+ Q +
Sbjct: 1502 KFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEE 1537
Score = 33.9 bits (76), Expect = 0.20
Identities = 25/98 (25%), Positives = 56/98 (57%), Gaps = 12/98 (12%)
Query: 20 RHIMMERERKRQEE------EEVDKMM---EQKMKEEQERRKKKEMEERMSLEETKEQIL 70
R M + ++ R++E +E D+ EQ ++E +E++ ++ +R LEE E L
Sbjct: 1595 RKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEE--EPQL 1652
Query: 71 KLEEKLLALQEEKHQLFLQLKKVLHE-EEKRRRKEQSD 107
+ +E+ L+ ++ + F + +++L E EE++ R+++ D
Sbjct: 1653 RRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERD 1690
Score = 33.1 bits (74), Expect = 0.35
Identities = 24/111 (21%), Positives = 51/111 (45%), Gaps = 10/111 (9%)
Query: 5 LERPKLSNAMARALHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSL-- 62
LER + ++ E + KR++E E E++++ ++ +++ ++ ++R L
Sbjct: 1166 LERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKW 1225
Query: 63 --EETKEQILKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQSDLTTL 111
E KE ++ + K+ E Q + L + + R R+ Q DL L
Sbjct: 1226 QWEPEKENAVR-DNKVYCKGRENEQF-----RQLEDSQLRDRQSQQDLQHL 1270
Score = 33.1 bits (74), Expect = 0.35
Identities = 20/63 (31%), Positives = 34/63 (53%), Gaps = 6/63 (9%)
Query: 15 ARALHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEE 74
+R + + E E+KR++E E +K++EE RR++KE + + E K Q K
Sbjct: 1857 SRREEQELWQEEEQKRRQERE------RKLREEHIRRQQKEEQRHRQVGEIKSQEGKGHG 1910
Query: 75 KLL 77
+LL
Sbjct: 1911 RLL 1913
Score = 31.6 bits (70), Expect = 1.0
Identities = 25/113 (22%), Positives = 53/113 (46%), Gaps = 16/113 (14%)
Query: 9 KLSNAMARALHRHIMMERERKRQEEEEVDKMMEQKMKEEQ---------------ERRKK 53
K++ A AL + ++ E++ + + + + +++ +E+Q +RR++
Sbjct: 80 KVAQACYYALGQATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQ 139
Query: 54 KEMEERMSLEETKEQILKLEE-KLLALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
K E+ L E +EQ K E + Q +L+ Q ++ EE+R +EQ
Sbjct: 140 KRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQ 192
>gi|239752551 PREDICTED: hypothetical protein [Homo sapiens]
Length = 238
Score = 55.5 bits (132), Expect = 7e-08
Identities = 30/89 (33%), Positives = 59/89 (66%), Gaps = 6/89 (6%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQERRKKKE---MEERMSLEETKEQILKLEEKLLAL 79
M ERE+K +EEEE+ + E+KM+E++E+ +++E E+ ++E +E++ + EEK+
Sbjct: 7 MREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQ 66
Query: 80 QE---EKHQLFLQLKKVLHEEEKRRRKEQ 105
+E E+ +L Q +K+ ++E+ R KE+
Sbjct: 67 EEKMWEQQRLPEQKEKMWEQDERLREKEE 95
Score = 50.1 bits (118), Expect = 3e-06
Identities = 32/90 (35%), Positives = 57/90 (63%), Gaps = 12/90 (13%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQE--RRKKKEMEERMS-----LEETKEQILKLEEK 75
M E++ + +E+EE +M EQKM ++ E R KKK EE+M ++E +E + + EEK
Sbjct: 83 MWEQDERLREKEE--RMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEK 140
Query: 76 LLALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
+ QE++ +++ Q +K+ +EEK R +E+
Sbjct: 141 M---QEQEEKMWEQEEKMREQEEKMREQEE 167
Score = 47.0 bits (110), Expect = 2e-05
Identities = 30/86 (34%), Positives = 55/86 (63%), Gaps = 7/86 (8%)
Query: 22 IMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKL---LA 78
+M E+E K QE+EE + E+KM E++E K +E EE+M E +E++ + EEK+
Sbjct: 20 MMREQEEKMQEQEEKMREQEEKMWEQEE--KMQEQEEKM--WEQEEKMWEQEEKMWEQQR 75
Query: 79 LQEEKHQLFLQLKKVLHEEEKRRRKE 104
L E+K +++ Q +++ +EE+ R ++
Sbjct: 76 LPEQKEKMWEQDERLREKEERMREQK 101
Score = 42.0 bits (97), Expect = 7e-04
Identities = 22/67 (32%), Positives = 44/67 (65%)
Query: 33 EEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKHQLFLQLKK 92
EEE + E+KM+EE+E +++E + + E+ +EQ K+ E+ +QE++ +++ Q +K
Sbjct: 3 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62
Query: 93 VLHEEEK 99
+ +EEK
Sbjct: 63 MWEQEEK 69
Score = 42.0 bits (97), Expect = 7e-04
Identities = 29/98 (29%), Positives = 55/98 (56%), Gaps = 8/98 (8%)
Query: 7 RPKLSNAMARALHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETK 66
R K + + + + RE+K+ +EE KM EQ+ K +++ E EE+M +E +
Sbjct: 91 REKEERMREQKMWQQVEKMREKKKTQEE---KMQEQEEKMQEQEEMMWEQEEKM--QEQE 145
Query: 67 EQILKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKE 104
E++ + EEK ++E++ ++ Q +K+ +EEK R E
Sbjct: 146 EKMWEQEEK---MREQEEKMREQEEKMQGQEEKMRDVE 180
Score = 40.8 bits (94), Expect = 0.002
Identities = 26/99 (26%), Positives = 58/99 (58%), Gaps = 13/99 (13%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQER--RKKKEMEERMSLEETKEQILKLEEKLLALQ 80
M E+E K E+EE + E+KM E++E+ ++++M E+ L E KE++ + +E+L +
Sbjct: 35 MREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKE 94
Query: 81 EE--KHQLFLQLKKVLH---------EEEKRRRKEQSDL 108
E + +++ Q++K+ +E++ + +EQ ++
Sbjct: 95 ERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEM 133
Score = 38.9 bits (89), Expect = 0.006
Identities = 27/94 (28%), Positives = 54/94 (57%), Gaps = 11/94 (11%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKE------EQERRK---KKEMEERMSLEETKEQILKLE 73
M E+E K +E+EE E+KM+E EQE + +++M E+ L E KE++ + +
Sbjct: 28 MQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQD 87
Query: 74 EKLLALQE--EKHQLFLQLKKVLHEEEKRRRKEQ 105
E+L +E + +++ Q++K+ +++ + K Q
Sbjct: 88 ERLREKEERMREQKMWQQVEKMREKKKTQEEKMQ 121
Score = 35.4 bits (80), Expect = 0.070
Identities = 17/59 (28%), Positives = 38/59 (64%)
Query: 47 EQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
E+ER +++E + R E +EQ K++E+ ++E++ +++ Q +K+ +EEK +E+
Sbjct: 3 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 54.3 bits (129), Expect = 1e-07
Identities = 29/92 (31%), Positives = 59/92 (64%), Gaps = 9/92 (9%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQERRKKKE---MEERMSLEETKEQILKLEEKLLA- 78
M ERE+K +EEEE+ + E+KM+E++E+ +++E E+ ++E +E++ + EEK+
Sbjct: 562 MREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQ 621
Query: 79 -----LQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
+QE++ ++ Q +K+ +EEK +E+
Sbjct: 622 EEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEE 653
Score = 52.4 bits (124), Expect = 6e-07
Identities = 30/88 (34%), Positives = 54/88 (61%), Gaps = 8/88 (9%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQER-----RKKKEMEERMSLEETKEQILKLEEKLL 77
M E+E K +E+EE E+KM+E++E+ K E EE ++E +E + + EEK+
Sbjct: 583 MQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKM- 641
Query: 78 ALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
QE++ +++ Q +K+ +EEK R +E+
Sbjct: 642 --QEQEEKMWEQEEKMREQEEKMREQEE 667
Score = 50.1 bits (118), Expect = 3e-06
Identities = 25/89 (28%), Positives = 59/89 (66%), Gaps = 6/89 (6%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQE--RRKKKEMEERMSLEETKEQILKLEEKLLA-- 78
+ E+E K +E+EE + E++++E+++ R ++KE+ E+ L E +EQ+ + EEK+
Sbjct: 264 LREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQE 323
Query: 79 --LQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
++E++ +++ Q +++ +E++ R +EQ
Sbjct: 324 EKMREQEEKMWRQEERLWEQEKQMREQEQ 352
Score = 48.9 bits (115), Expect = 6e-06
Identities = 25/84 (29%), Positives = 56/84 (66%), Gaps = 1/84 (1%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKH 84
++E K +EEE + + E+KM+EE+E +++E + + E+ +EQ K+ E+ +QE++
Sbjct: 551 DQEEKMREEERM-REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEE 609
Query: 85 QLFLQLKKVLHEEEKRRRKEQSDL 108
+++ Q +K+ +EE+ + +EQ ++
Sbjct: 610 KMWEQEEKMWEQEEEDKMQEQEEM 633
Score = 48.5 bits (114), Expect = 8e-06
Identities = 26/81 (32%), Positives = 52/81 (64%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKH 84
E E K QE+EE+ E+KM+E++E+ ++E + R E+ +EQ K++ + ++E++
Sbjct: 622 EEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEE 681
Query: 85 QLFLQLKKVLHEEEKRRRKEQ 105
++ Q +K+ +EEK R +E+
Sbjct: 682 KMQGQEEKMREQEEKMRGQEE 702
Score = 48.1 bits (113), Expect = 1e-05
Identities = 26/83 (31%), Positives = 53/83 (63%), Gaps = 1/83 (1%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEE 82
M +E + +E+E + E+KM+ +++R +++E E R +E +EQ KL E+ +QE+
Sbjct: 257 MWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQ-KKLREQEEQMQEQ 315
Query: 83 KHQLFLQLKKVLHEEEKRRRKEQ 105
+ +++ Q +K+ +EEK R+E+
Sbjct: 316 EEKMWEQEEKMREQEEKMWRQEE 338
Score = 47.8 bits (112), Expect = 1e-05
Identities = 31/83 (37%), Positives = 49/83 (59%), Gaps = 5/83 (6%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEE 82
M E+E K QE+EE E+KM E++E K +E EE M +E K Q + EEK+ +E+
Sbjct: 597 MWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQ--EQEEKMWEQEEK 654
Query: 83 KHQLFLQLKKVLHEEEKRRRKEQ 105
+ Q +K+ +EEK + +E+
Sbjct: 655 MRE---QEEKMREQEEKMQGQEE 674
Score = 47.8 bits (112), Expect = 1e-05
Identities = 30/86 (34%), Positives = 53/86 (61%), Gaps = 4/86 (4%)
Query: 22 IMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETK--EQILKLEEKLLAL 79
+M E+E K QE+EE KM EQ+ K ++ K +E EE+M +E K EQ K++ + +
Sbjct: 633 MMWEQEEKMQEQEE--KMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKM 690
Query: 80 QEEKHQLFLQLKKVLHEEEKRRRKEQ 105
+E++ ++ Q +K+ +EEK +E+
Sbjct: 691 REQEEKMRGQEEKMWGQEEKMWGQEE 716
Score = 47.0 bits (110), Expect = 2e-05
Identities = 34/115 (29%), Positives = 61/115 (53%), Gaps = 14/115 (12%)
Query: 5 LERPK--LSNAMARALHRHIMMERERKRQEEEEVDKMMEQKMKEEQERR----KKKEMEE 58
LER K L L + + E R++E+++ K E+ ++E+ R K +E EE
Sbjct: 217 LERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEE 276
Query: 59 RMSLEETK----EQILKLEEKLL----ALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
+M +E + E+ L+ +EK L L+E++ Q+ Q +K+ +EEK R +E+
Sbjct: 277 KMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEE 331
Score = 47.0 bits (110), Expect = 2e-05
Identities = 31/92 (33%), Positives = 56/92 (60%), Gaps = 11/92 (11%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQER-----RKKKEMEERMSLEETK----EQILKLE 73
M E+E K E+EE + E+KM+E++E+ K +E EE+M +E K E+ ++ +
Sbjct: 641 MQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQ 700
Query: 74 EKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
E+ + QEEK ++ Q +K+ +EE R ++E+
Sbjct: 701 EEKMWGQEEK--MWGQEEKMWGQEEMREKEER 730
Score = 46.6 bits (109), Expect = 3e-05
Identities = 28/84 (33%), Positives = 52/84 (61%), Gaps = 4/84 (4%)
Query: 24 MERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETK--EQILKLEEKLLALQE 81
M R+ KR E+E K + ++ KE +E++K +E EE+M +E K EQ K+ E+ +
Sbjct: 278 MRRQEKRLREQE--KELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWR 335
Query: 82 EKHQLFLQLKKVLHEEEKRRRKEQ 105
++ +L+ Q K++ +E+K R +E+
Sbjct: 336 QEERLWEQEKQMREQEQKMRDQEE 359
Score = 45.8 bits (107), Expect = 5e-05
Identities = 28/115 (24%), Positives = 62/115 (53%), Gaps = 19/115 (16%)
Query: 6 ERPKLSNAMARALHRHIMMERERKRQEEEEVDKMMEQKMKEEQER--------------- 50
E+ K+ + + ERE+K +EEEE + E+KM++++E
Sbjct: 377 EQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLP 436
Query: 51 RKKKEMEERMSLEETKEQILKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
+K+++ E+ ++E +E+I + EEK+ ++ +++ Q KK+ +E+ R +++Q
Sbjct: 437 EQKEKLWEQEKMQEQEEKIWEQEEKI----RDQEEMWGQEKKMWRQEKMREQEDQ 487
Score = 44.7 bits (104), Expect = 1e-04
Identities = 32/88 (36%), Positives = 53/88 (60%), Gaps = 9/88 (10%)
Query: 27 ERKRQEEE---EVDKMMEQ--KMKEEQ--ERRKKKEMEERMSLEETKEQILKLEEKLLAL 79
ER R++EE E +KM EQ KM+EE+ R+KK EE ++ E +E++ K EE +
Sbjct: 366 ERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQ 425
Query: 80 QEE--KHQLFLQLKKVLHEEEKRRRKEQ 105
+E+ + Q + K+ L E+EK + +E+
Sbjct: 426 EEKEWQQQRLPEQKEKLWEQEKMQEQEE 453
Score = 44.7 bits (104), Expect = 1e-04
Identities = 37/106 (34%), Positives = 57/106 (53%), Gaps = 14/106 (13%)
Query: 9 KLSNAMARALHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQ 68
+L R + M E+E K QEEE + + E+KM+EE+E +E EE+M +E E
Sbjct: 367 RLREKEERMREQEKMWEQEEKMQEEERI-REREKKMREEEE--TMREQEEKMQKQE--EN 421
Query: 69 ILKLEEK---LLALQEEKHQLFLQLK------KVLHEEEKRRRKEQ 105
+ + EEK L E+K +L+ Q K K+ +EEK R +E+
Sbjct: 422 MWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEE 467
Score = 44.3 bits (103), Expect = 2e-04
Identities = 31/83 (37%), Positives = 53/83 (63%), Gaps = 7/83 (8%)
Query: 26 RERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEET---KEQILKLEEKLLALQEE 82
RE+K+ ++E +KM E+K +EQE+ K + EE+M EE +E+ ++ EE+++ QEE
Sbjct: 524 REQKKMWQQE-EKMREEKKTQEQEK-KTWDQEEKMREEERMREREKKMREEEEMMREQEE 581
Query: 83 KHQLFLQLKKVLHEEEKRRRKEQ 105
K Q Q +K+ +EEK +E+
Sbjct: 582 KMQ--EQEEKMREQEEKMWEQEE 602
Score = 42.7 bits (99), Expect = 4e-04
Identities = 24/86 (27%), Positives = 50/86 (58%), Gaps = 7/86 (8%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQER---RKKKEMEERMSLEETKEQILKLEEKLLAL 79
M E+E K E+EE + E+KM ++ER ++K+ E+ + + +E++ + +E+L
Sbjct: 312 MQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERL--- 368
Query: 80 QEEKHQLFLQLKKVLHEEEKRRRKEQ 105
EK + + +K+ +EEK + +E+
Sbjct: 369 -REKEERMREQEKMWEQEEKMQEEER 393
Score = 42.4 bits (98), Expect = 6e-04
Identities = 23/84 (27%), Positives = 54/84 (64%), Gaps = 4/84 (4%)
Query: 24 MERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETK--EQILKLEEKLLALQE 81
+ ++K +E+EE + E+KM E++E K +E EE+M +E + EQ ++ E+ +++
Sbjct: 299 LREQKKLREQEEQMQEQEEKMWEQEE--KMREQEEKMWRQEERLWEQEKQMREQEQKMRD 356
Query: 82 EKHQLFLQLKKVLHEEEKRRRKEQ 105
++ +++ Q +++ +EE+ R +E+
Sbjct: 357 QEERMWEQDERLREKEERMREQEK 380
Score = 42.0 bits (97), Expect = 7e-04
Identities = 28/95 (29%), Positives = 56/95 (58%), Gaps = 14/95 (14%)
Query: 23 MMERERKRQEEEE-----VDKMMEQKMKEEQERRKKKEMEERMSLEE----TKEQILKLE 73
M E+E K +E+EE +++ EQ+ + ++ +K ++ EERM ++ KE+ ++ +
Sbjct: 319 MWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQ 378
Query: 74 EKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQSDL 108
EK+ QEEK +Q ++ + E EK+ R+E+ +
Sbjct: 379 EKMWE-QEEK----MQEEERIREREKKMREEEETM 408
Score = 40.8 bits (94), Expect = 0.002
Identities = 28/96 (29%), Positives = 54/96 (56%), Gaps = 4/96 (4%)
Query: 14 MARALHRHIMMERERKRQEEE--EVDKMMEQKMKEEQERRKKKEMEERMSLEETK--EQI 69
M R R E+E + QE+E E K+ EQ+ + +++ K E EE+M +E K Q
Sbjct: 278 MRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQE 337
Query: 70 LKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
+L E+ ++E++ ++ Q +++ ++E+ R KE+
Sbjct: 338 ERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEE 373
Score = 40.8 bits (94), Expect = 0.002
Identities = 30/92 (32%), Positives = 58/92 (63%), Gaps = 13/92 (14%)
Query: 23 MMERERKRQEEEEVDKMMEQ--KMKEEQERRKKK----EMEERMSLEE---TKEQILKLE 73
M E+E+K +++EE +M EQ +++E++ER +++ E EE+M EE +E+ ++ E
Sbjct: 347 MREQEQKMRDQEE--RMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREE 404
Query: 74 EKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
E+ + QEEK Q Q + + +EEK ++++
Sbjct: 405 EETMREQEEKMQ--KQEENMWEQEEKEWQQQR 434
Score = 40.0 bits (92), Expect = 0.003
Identities = 27/83 (32%), Positives = 46/83 (55%), Gaps = 2/83 (2%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEE 82
M E+E + E+EE + EQKM +++ER +++ R E +EQ +++ +E+
Sbjct: 481 MREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEK 540
Query: 83 KHQLFLQLKKVLHEEEKRRRKEQ 105
K Q Q KK +EEK R +E+
Sbjct: 541 KTQ--EQEKKTWDQEEKMREEER 561
Score = 39.3 bits (90), Expect = 0.005
Identities = 18/83 (21%), Positives = 54/83 (65%), Gaps = 3/83 (3%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEE 82
+ E+E+ +++EE++ + E+ +E+ ++K+M + + E ++Q+ + EEK ++++
Sbjct: 442 LWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEK---MRDQ 498
Query: 83 KHQLFLQLKKVLHEEEKRRRKEQ 105
+ +++ Q +++ ++E+ R KE+
Sbjct: 499 EQKMWDQEERMWEQDERLREKEE 521
Score = 38.5 bits (88), Expect = 0.008
Identities = 24/83 (28%), Positives = 47/83 (56%), Gaps = 2/83 (2%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEE 82
M E+E K +++E+ E++M E+ ER ++KE R + +++ EEK QE+
Sbjct: 488 MWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEK--KTQEQ 545
Query: 83 KHQLFLQLKKVLHEEEKRRRKEQ 105
+ + + Q +K+ EE R R+++
Sbjct: 546 EKKTWDQEEKMREEERMREREKK 568
Score = 36.2 bits (82), Expect = 0.041
Identities = 26/112 (23%), Positives = 56/112 (50%), Gaps = 11/112 (9%)
Query: 6 ERPKLSNAMARALHRHIMMERERKRQEEEEVDKMMEQKMKEEQER-RKKKEMEERMSLEE 64
++ +L + + M E+E K E+EE + E+ +E++ R++K E+ + E
Sbjct: 431 QQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWE 490
Query: 65 TKEQILKLEEKLLALQE----------EKHQLFLQLKKVLHEEEKRRRKEQS 106
+E++ E+K+ +E EK + + KK+ +EEK R ++++
Sbjct: 491 QEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKT 542
Score = 34.7 bits (78), Expect = 0.12
Identities = 30/121 (24%), Positives = 61/121 (50%), Gaps = 21/121 (17%)
Query: 6 ERPKLSNAMARALHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERM----- 60
E K +A++ L+R+ + E K++ E +K+ + ++ + + KE++ ++
Sbjct: 163 ELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKF 222
Query: 61 --------SLEE---TKEQILKLEEKLLALQEEK-----HQLFLQLKKVLHEEEKRRRKE 104
+L+E +E+ L+ +EK + QEEK +L Q K+ +EEK RR+E
Sbjct: 223 LLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQE 282
Query: 105 Q 105
+
Sbjct: 283 K 283
Score = 34.7 bits (78), Expect = 0.12
Identities = 28/86 (32%), Positives = 49/86 (56%), Gaps = 11/86 (12%)
Query: 24 MERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEK 83
M R+ K +E+E D+M EQ+ K + +K + EERM EQ +L EK ++E+K
Sbjct: 475 MWRQEKMREQE--DQMWEQEEKMRDQEQKMWDQEERMW-----EQDERLREKEERMREQK 527
Query: 84 HQLFLQLKKVLHEEEKRRRKEQSDLT 109
+++ Q +K+ E+++ +EQ T
Sbjct: 528 -KMWQQEEKM---REEKKTQEQEKKT 549
Score = 34.7 bits (78), Expect = 0.12
Identities = 26/88 (29%), Positives = 53/88 (60%), Gaps = 5/88 (5%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQER-RKKKEM---EERMSLEE-TKEQILKLEEKLL 77
M ++E+K ++EE +++++E++ER R++K+M EE+M E+ T+EQ K ++
Sbjct: 495 MRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEE 554
Query: 78 ALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
++EE+ + K EE R ++E+
Sbjct: 555 KMREEERMREREKKMREEEEMMREQEEK 582
Score = 32.7 bits (73), Expect = 0.45
Identities = 19/108 (17%), Positives = 57/108 (52%), Gaps = 3/108 (2%)
Query: 4 LLERPKLSNAMARALHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLE 63
L E+ +L+ + + ++ + + + + + ++ ++EE R++++ E+ +
Sbjct: 192 LQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIR 251
Query: 64 ETKEQILKLEEKLLALQ---EEKHQLFLQLKKVLHEEEKRRRKEQSDL 108
+ +E++ + EE+L + E+ + + +K L E+EK R+++ +L
Sbjct: 252 KQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKEL 299
Score = 31.6 bits (70), Expect = 1.0
Identities = 26/92 (28%), Positives = 45/92 (48%), Gaps = 20/92 (21%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQERRKKKE-----MEERMSLEETK----------- 66
M +E K +E+EE + E+KM+E++E+ + +E EE+M +E K
Sbjct: 669 MQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKE 728
Query: 67 ----EQILKLEEKLLALQEEKHQLFLQLKKVL 94
+Q K++E+L +E + L KVL
Sbjct: 729 ERIRDQKEKMQERLPEHEERCSEPCLPPSKVL 760
Score = 28.9 bits (63), Expect = 6.5
Identities = 33/132 (25%), Positives = 58/132 (43%), Gaps = 12/132 (9%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQE--E 82
E + + QEE KM Q+ K ++ K + EE+M +E E++ EEK+ +E E
Sbjct: 673 EEKMREQEE----KMQGQEEKMREQEEKMRGQEEKMWGQE--EKMWGQEEKMWGQEEMRE 726
Query: 83 KHQLFLQLKKVLHEEEKRRRKEQSDLTTLTSAAYQQSLTVHTGTHLLSMQGSPGGHNRPG 142
K + K+ + +E +E+ L + +++ HTG+ + G G P
Sbjct: 727 KEERIRDQKEKM-QERLPEHEERCSEPCLPPSKVLCNMS-HTGS--VEPAGGEAGEGSPQ 782
Query: 143 TLMAADRAKQMF 154
A Q+F
Sbjct: 783 DNPTAQEIMQLF 794
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 53.5 bits (127), Expect = 2e-07
Identities = 32/87 (36%), Positives = 56/87 (64%), Gaps = 4/87 (4%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKL-EEKLLALQE 81
M ERE+K +EEEE+ + E+KM+E++E+ +++E E E+ EQ K+ E++ L Q+
Sbjct: 715 MREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQK 774
Query: 82 EK---HQLFLQLKKVLHEEEKRRRKEQ 105
EK H+ + +K+ +EEK R +E+
Sbjct: 775 EKLWEHEKMQEQEKIWEQEEKMRDQEE 801
Score = 52.4 bits (124), Expect = 6e-07
Identities = 29/88 (32%), Positives = 57/88 (64%), Gaps = 5/88 (5%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQERRKKKE---MEERMSLEETKEQILKLEEKLLAL 79
M ERE+K +EEEE+ + E+KM+E++E+ +++E E+ ++E +E++ + EEK+
Sbjct: 591 MREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQ 650
Query: 80 QEE--KHQLFLQLKKVLHEEEKRRRKEQ 105
+E+ + Q + K+ L E EK + +E+
Sbjct: 651 EEKMWEQQRLPEQKEKLWEHEKMQEQEK 678
Score = 48.1 bits (113), Expect = 1e-05
Identities = 29/86 (33%), Positives = 54/86 (62%), Gaps = 4/86 (4%)
Query: 24 MERERKRQEEEEVDKMMEQKMKEEQE-RRKKKEM-EERMSLEETKEQILKLEEKLLALQE 81
M E+K QE+E+ + E+KM+EE+ R ++K+M EE ++ E +E++ K EE + +E
Sbjct: 426 MREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEE 485
Query: 82 E--KHQLFLQLKKVLHEEEKRRRKEQ 105
+ + Q + K+ L E+EK + +E+
Sbjct: 486 KEWQQQRLPEQKEKLWEQEKMQEQEE 511
Score = 47.0 bits (110), Expect = 2e-05
Identities = 35/95 (36%), Positives = 56/95 (58%), Gaps = 8/95 (8%)
Query: 22 IMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETK--EQILKL-EEKLLA 78
+M E+E K QE+EE KM EQ+ K ++ K +E EE+M +E K EQ K+ E++ L
Sbjct: 604 MMREQEEKMQEQEE--KMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLP 661
Query: 79 LQEEK---HQLFLQLKKVLHEEEKRRRKEQSDLTT 110
Q+EK H+ + +K+ +EEK +E+ + T
Sbjct: 662 EQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKT 696
Score = 46.6 bits (109), Expect = 3e-05
Identities = 23/84 (27%), Positives = 52/84 (61%), Gaps = 3/84 (3%)
Query: 25 ERERKRQEE---EEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQE 81
+ ER R++E E+V+KM E+K +EQE++ + + E+ E +E+ K+ E+ ++E
Sbjct: 409 KEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMRE 468
Query: 82 EKHQLFLQLKKVLHEEEKRRRKEQ 105
++ ++ Q + + +EEK ++++
Sbjct: 469 QEEKMQKQEENMWEQEEKEWQQQR 492
Score = 46.6 bits (109), Expect = 3e-05
Identities = 27/82 (32%), Positives = 54/82 (65%), Gaps = 3/82 (3%)
Query: 24 MERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEK 83
ME++ + QE++ D+ E+KM+EE ER +++E + R E +EQ K++E+ +QE++
Sbjct: 567 MEKKTQEQEKKTWDQ--EEKMREE-ERMREREKKMREEEEMMREQEEKMQEQEEKMQEQE 623
Query: 84 HQLFLQLKKVLHEEEKRRRKEQ 105
+++ Q +K+ +EEK +E+
Sbjct: 624 EKMWEQEEKMQEQEEKMWEQEE 645
Score = 46.2 bits (108), Expect = 4e-05
Identities = 31/91 (34%), Positives = 53/91 (58%), Gaps = 5/91 (5%)
Query: 18 LHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEET---KEQILKLEE 74
L H M+ + K QE+EE E+ K+ QE+ KK +E+M EE+ +E+ ++ EE
Sbjct: 667 LWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEE 726
Query: 75 KLLALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
+++ QEEK Q Q +K+ +EE+ +E+
Sbjct: 727 EMMREQEEKMQ--EQEEKMQEQEEEMWEQEE 755
Score = 45.8 bits (107), Expect = 5e-05
Identities = 33/95 (34%), Positives = 55/95 (57%), Gaps = 14/95 (14%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQERRKKK---------EMEERMSLEE---TKEQIL 70
M E+E + E+EE + EQKM +++ER +KK + EE+M EE +E+ +
Sbjct: 539 MREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKM 598
Query: 71 KLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
+ EE+++ QEEK Q Q +K+ +EEK +E+
Sbjct: 599 REEEEMMREQEEKMQ--EQEEKMQEQEEKMWEQEE 631
Score = 45.4 bits (106), Expect = 7e-05
Identities = 27/91 (29%), Positives = 57/91 (62%), Gaps = 10/91 (10%)
Query: 23 MMERERKRQEEEEVDKMMEQKMK----EEQERRKKKEMEERMSLEETKEQILKLEEKLL- 77
+ E+E K +E+EE KM Q+ + E++ R ++KE+ E+ L E +EQ+ + EEK+
Sbjct: 302 LREQEGKMREQEE--KMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWE 359
Query: 78 ---ALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
++E++ +++ Q +++ +E++ R +EQ
Sbjct: 360 QEEKMREQEEKMWRQEERLWEQEKQMREQEQ 390
Score = 45.4 bits (106), Expect = 7e-05
Identities = 26/96 (27%), Positives = 56/96 (58%), Gaps = 19/96 (19%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQER---------------RKKKEMEERMSLEETKEQI 69
ERE+K +EEEE + E+KM++++E +K+++ E+ ++E +E+I
Sbjct: 454 EREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKI 513
Query: 70 LKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
+ EEK+ ++ +++ Q KK+ +E+ R +++Q
Sbjct: 514 WEQEEKI----RDQEEMWGQEKKMWRQEKMREQEDQ 545
Score = 45.1 bits (105), Expect = 9e-05
Identities = 36/116 (31%), Positives = 62/116 (53%), Gaps = 16/116 (13%)
Query: 5 LERPK--LSNAMARALHRHIMMERERKRQEEEEVDKMMEQKMKEEQER-----RKKKEME 57
LER K L L + + E R++E+++ K E+KM ++ER K +E E
Sbjct: 255 LERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQ-EEKMWRQEERLREQEGKMREQE 313
Query: 58 ERMSLEETK----EQILKLEEKLL----ALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
E+M +E + E+ L+ +EK L L+E++ Q+ Q +K+ +EEK R +E+
Sbjct: 314 EKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEE 369
Score = 44.7 bits (104), Expect = 1e-04
Identities = 25/83 (30%), Positives = 52/83 (62%), Gaps = 1/83 (1%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEE 82
M +E + +E+E + E+KM +++R +++E E R +E +EQ +L E+ +QE+
Sbjct: 295 MWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQ-KELREQEEQMQEQ 353
Query: 83 KHQLFLQLKKVLHEEEKRRRKEQ 105
+ +++ Q +K+ +EEK R+E+
Sbjct: 354 EEKMWEQEEKMREQEEKMWRQEE 376
Score = 44.7 bits (104), Expect = 1e-04
Identities = 24/75 (32%), Positives = 50/75 (66%), Gaps = 1/75 (1%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKH 84
++E K +EEE + + E+KM+EE+E +++E + + E+ +EQ K+ E+ +QE++
Sbjct: 580 DQEEKMREEERM-REREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEE 638
Query: 85 QLFLQLKKVLHEEEK 99
+++ Q +K+ +EEK
Sbjct: 639 KMWEQEEKMWEQEEK 653
Score = 44.3 bits (103), Expect = 2e-04
Identities = 28/88 (31%), Positives = 52/88 (59%), Gaps = 14/88 (15%)
Query: 23 MMERERKRQEEEEVDKMM---------EQKMKEEQ--ERRKKKEMEERMSLEETKEQILK 71
M E+E K E+E+++K ++KM+EE+ R+KK EE + E +E++ +
Sbjct: 679 MQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQE 738
Query: 72 LEEKLLALQEEKHQLFLQLKKVLHEEEK 99
EEK +QE++ +++ Q +K+ +EEK
Sbjct: 739 QEEK---MQEQEEEMWEQEEKMWEQEEK 763
Score = 43.9 bits (102), Expect = 2e-04
Identities = 27/84 (32%), Positives = 52/84 (61%), Gaps = 4/84 (4%)
Query: 24 MERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETK--EQILKLEEKLLALQE 81
M R+ KR E+E K + ++ KE +E+++ +E EE+M +E K EQ K+ E+ +
Sbjct: 316 MWRQEKRLREQE--KELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWR 373
Query: 82 EKHQLFLQLKKVLHEEEKRRRKEQ 105
++ +L+ Q K++ +E+K R +E+
Sbjct: 374 QEERLWEQEKQMREQEQKMRDQEE 397
Score = 43.9 bits (102), Expect = 2e-04
Identities = 30/91 (32%), Positives = 57/91 (62%), Gaps = 7/91 (7%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETK-EQILKL-EEKLLALQ 80
+ E+E++ +E+E+ + E++M E+ ER ++KE ERM +E EQ+ K+ EEK + Q
Sbjct: 378 LWEQEKQMREQEQKMRDQEERMWEQDERLREKE--ERMREQEKMWEQVEKMREEKKMQEQ 435
Query: 81 EEK---HQLFLQLKKVLHEEEKRRRKEQSDL 108
E+K + +Q ++ + E EK+ R+E+ +
Sbjct: 436 EKKTRDQEEKMQEEERIREREKKMREEEETM 466
Score = 42.4 bits (98), Expect = 6e-04
Identities = 25/97 (25%), Positives = 57/97 (58%), Gaps = 11/97 (11%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQER---RKKKEMEERMSLEETKEQILKLEEKLLAL 79
M E+E K E+EE + E+KM ++ER ++K+ E+ + + +E++ + +E+L
Sbjct: 350 MQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREK 409
Query: 80 QE---EKHQLFLQLKKV-----LHEEEKRRRKEQSDL 108
+E E+ +++ Q++K+ + E+EK+ R ++ +
Sbjct: 410 EERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKM 446
Score = 42.4 bits (98), Expect = 6e-04
Identities = 29/90 (32%), Positives = 50/90 (55%), Gaps = 9/90 (10%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQERRKKKE-------MEERMSLEETKEQILKLEEK 75
M E+E K E+EE E+KM E+Q ++KE M+E+ ++E +E+I + E+
Sbjct: 633 MQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKM 692
Query: 76 LLALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
QE++ + + Q K + EEE R +E+
Sbjct: 693 EKKTQEQEKKTWDQEK--MREEESMREREK 720
Score = 42.4 bits (98), Expect = 6e-04
Identities = 24/84 (28%), Positives = 51/84 (60%), Gaps = 5/84 (5%)
Query: 27 ERKRQEEEEVDKMMEQKMKEEQERRKKKE---MEERMSLEETKEQILKLEEKLLALQEE- 82
++++ EEE + E+KM+EE+E +++E E+ ++E +E++ + EEK+ +E+
Sbjct: 705 DQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKM 764
Query: 83 -KHQLFLQLKKVLHEEEKRRRKEQ 105
+ Q + K+ L E EK + +E+
Sbjct: 765 WEQQRLPEQKEKLWEHEKMQEQEK 788
Score = 41.2 bits (95), Expect = 0.001
Identities = 24/91 (26%), Positives = 53/91 (58%), Gaps = 12/91 (13%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQERRKKKE--------MEERMSLEETKEQILKLEE 74
M E+E+K +++EE +++++E++ER +++E M E ++E +++ EE
Sbjct: 385 MREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEE 444
Query: 75 KLLALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
K+ +E+ ++ + KK+ EEE R +E+
Sbjct: 445 KM----QEEERIREREKKMREEEETMREQEE 471
Score = 40.8 bits (94), Expect = 0.002
Identities = 23/92 (25%), Positives = 54/92 (58%), Gaps = 6/92 (6%)
Query: 16 RALHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETK--EQILKLE 73
R + + ++E + QEE+ M EQ+ K ++ K +E EE+M +E + EQ ++
Sbjct: 331 REQEKELREQKELREQEEQ----MQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMR 386
Query: 74 EKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
E+ +++++ +++ Q +++ +EE+ R +E+
Sbjct: 387 EQEQKMRDQEERMWEQDERLREKEERMREQEK 418
Score = 40.8 bits (94), Expect = 0.002
Identities = 29/90 (32%), Positives = 54/90 (60%), Gaps = 10/90 (11%)
Query: 23 MMERERKRQEEEEV-----DKMMEQKMKEEQERRKKKEMEERMSLEETKEQ--ILKLEEK 75
M E+E K QE+EE +KM EQ+ K +++R ++ E+ E+ +EQ I + EEK
Sbjct: 736 MQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEK 795
Query: 76 LLALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
+++++ ++ Q +K+ +EEK R +E+
Sbjct: 796 ---MRDQEEKMRGQEEKMRGQEEKMRGQEE 822
Score = 38.9 bits (89), Expect = 0.006
Identities = 27/100 (27%), Positives = 54/100 (54%), Gaps = 2/100 (2%)
Query: 6 ERPKLSNAMARALHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEET 65
E K+ + + M+ E + +E E+ + E+ M+E++E+ +K+E E EE
Sbjct: 428 EEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQE-ENMWEQEEK 486
Query: 66 KEQILKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
+ Q +L E+ L E++ ++ Q +K+ +EEK R +E+
Sbjct: 487 EWQQQRLPEQKEKLWEQE-KMQEQEEKIWEQEEKIRDQEE 525
Score = 38.9 bits (89), Expect = 0.006
Identities = 29/99 (29%), Positives = 55/99 (55%), Gaps = 11/99 (11%)
Query: 18 LHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKE-----MEERMSLEETK-----E 67
L H M+ + K E+EE + E+KM+ ++E+ + +E EE+M +E K E
Sbjct: 777 LWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEE 836
Query: 68 QILKLEEKLLALQEE-KHQLFLQLKKVLHEEEKRRRKEQ 105
++ EEK+ +E+ + ++ Q +K+ +EEK R +E+
Sbjct: 837 KMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEE 875
Score = 38.1 bits (87), Expect = 0.011
Identities = 24/95 (25%), Positives = 52/95 (54%), Gaps = 12/95 (12%)
Query: 23 MMERERKRQEEEEV---DKMMEQKMKEEQE---------RRKKKEMEERMSLEETKEQIL 70
M E++R +++E++ +KM EQ+ +EQE +K +E E++ +E +
Sbjct: 654 MWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEE 713
Query: 71 KLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
+ E+ ++EE+ + Q +K+ +EEK + +E+
Sbjct: 714 SMREREKKMREEEEMMREQEEKMQEQEEKMQEQEE 748
Score = 37.4 bits (85), Expect = 0.018
Identities = 21/88 (23%), Positives = 56/88 (63%), Gaps = 8/88 (9%)
Query: 26 RERKRQEEEEVDKMMEQK-MKEEQERRKKKE---MEERMSLEETKEQILKLEEKL----L 77
RE++++ E+ ++ EQK ++E++E+ +++E E+ + E +E++ + EE+L
Sbjct: 324 REQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEK 383
Query: 78 ALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
++E++ ++ Q +++ ++E+ R KE+
Sbjct: 384 QMREQEQKMRDQEERMWEQDERLREKEE 411
Score = 37.4 bits (85), Expect = 0.018
Identities = 26/82 (31%), Positives = 46/82 (56%), Gaps = 3/82 (3%)
Query: 24 MERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEK 83
M R+ K +E+E D+M EQ+ K + +K + EERM ++T+EQ K ++ ++EE+
Sbjct: 533 MWRQEKMREQE--DQMWEQEEKMRDQEQKMWDQEERME-KKTQEQEKKTWDQEEKMREEE 589
Query: 84 HQLFLQLKKVLHEEEKRRRKEQ 105
+ K EE R ++E+
Sbjct: 590 RMREREKKMREEEEMMREQEEK 611
Score = 36.2 bits (82), Expect = 0.041
Identities = 31/100 (31%), Positives = 52/100 (52%), Gaps = 8/100 (8%)
Query: 6 ERPKLSNAMARALHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEET 65
E+ +L + M E+E+ ++EE KM +Q+ K + K + EE+M +E
Sbjct: 766 EQQRLPEQKEKLWEHEKMQEQEKIWEQEE---KMRDQEEKMRGQEEKMRGQEEKMRGQE- 821
Query: 66 KEQILKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
E++ EEK+ QEEK ++ Q +K+ +EEK K Q
Sbjct: 822 -EKMWGQEEKMWG-QEEK--MWGQEEKMWGQEEKMEEKMQ 857
Score = 35.8 bits (81), Expect = 0.053
Identities = 17/78 (21%), Positives = 47/78 (60%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEE 82
+ E+E+ +++EE++ + E+ +E+ ++K+M + + E ++Q+ + EEK+ +++
Sbjct: 500 LWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQK 559
Query: 83 KHQLFLQLKKVLHEEEKR 100
+++K E+EK+
Sbjct: 560 MWDQEERMEKKTQEQEKK 577
Score = 35.4 bits (80), Expect = 0.070
Identities = 22/101 (21%), Positives = 53/101 (52%), Gaps = 1/101 (0%)
Query: 6 ERPKLSNAMARALHRHIMMERERKRQEEEEVDKMMEQKMKEEQER-RKKKEMEERMSLEE 64
++ +L + + M E+E K E+EE + E+ +E++ R++K E+ + E
Sbjct: 489 QQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWE 548
Query: 65 TKEQILKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
+E++ E+K+ +E + + +K ++E++ R+E+
Sbjct: 549 QEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEE 589
Score = 34.3 bits (77), Expect = 0.16
Identities = 23/93 (24%), Positives = 47/93 (50%), Gaps = 10/93 (10%)
Query: 23 MMERERKRQEEE----------EVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKL 72
M E+E K +++ E +KM EQ+ K ++ K ++ EE E+ + K+
Sbjct: 480 MWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKM 539
Query: 73 EEKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
E+ + E++ ++ Q +K+ +EE+ +K Q
Sbjct: 540 REQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQ 572
Score = 33.5 bits (75), Expect = 0.26
Identities = 26/103 (25%), Positives = 53/103 (51%), Gaps = 6/103 (5%)
Query: 6 ERPKLSNAMARALHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEME---ERMSL 62
E K +A++ L+R+ + E K++ E +K+ + ++ + + KE++ ER
Sbjct: 201 ELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKF 260
Query: 63 EETKEQILKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
+ Q L+E++ +EE + Q KK+ +EEK R+E+
Sbjct: 261 LLPQVQTNTLQEEMWRQEEELRE---QEKKIRKQEEKMWRQEE 300
Score = 33.5 bits (75), Expect = 0.26
Identities = 21/90 (23%), Positives = 53/90 (58%), Gaps = 8/90 (8%)
Query: 26 RERKRQEEEE---VDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLL----A 78
+E KR+ E + ++ ++EE R++++ E+ + + +E++ + EE+L
Sbjct: 249 KELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGK 308
Query: 79 LQEEKHQLFLQLKKVLHEEEKRRRKEQSDL 108
++E++ +++ Q K+ L E+EK R+++ +L
Sbjct: 309 MREQEEKMWRQEKR-LREQEKELREQEKEL 337
Score = 31.6 bits (70), Expect = 1.0
Identities = 19/61 (31%), Positives = 35/61 (57%), Gaps = 1/61 (1%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEE 82
M +E K +EE E+KM+E+ + +++K E+ + +E++ + EEK+ QEE
Sbjct: 831 MWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRG-QEE 889
Query: 83 K 83
K
Sbjct: 890 K 890
Score = 31.2 bits (69), Expect = 1.3
Identities = 24/89 (26%), Positives = 51/89 (57%), Gaps = 20/89 (22%)
Query: 25 ERERKRQEEEEV----DKM--MEQKMKEEQERR--KKKEMEERMSLEETKEQILKLEEKL 76
+ E+ R +EE++ +KM E+KM ++E+ ++++MEE+M +E K
Sbjct: 813 QEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEK---------- 862
Query: 77 LALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
++E++ ++ Q +K+ +EEK R +E+
Sbjct: 863 --MREQEEKMRGQEEKMREQEEKMRGQEE 889
Score = 29.3 bits (64), Expect = 5.0
Identities = 19/61 (31%), Positives = 33/61 (54%), Gaps = 1/61 (1%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEE 82
M +E K +EE E+KM ++E+ ++K + + E +E++ EEK+ QEE
Sbjct: 824 MWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMRE-QEE 882
Query: 83 K 83
K
Sbjct: 883 K 883
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 53.1 bits (126), Expect = 3e-07
Identities = 26/92 (28%), Positives = 58/92 (63%), Gaps = 4/92 (4%)
Query: 18 LHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKL- 76
+H + E KRQE+EE+ + E+ ++E+ R+K++M E+ + + +E++ + EEK+
Sbjct: 446 IHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMH 505
Query: 77 ---LALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
++E++ +++ Q +K+ +EEK R +E+
Sbjct: 506 DQEEKIREQEEKMWRQEEKIREQEEKIREQEE 537
Score = 52.0 bits (123), Expect = 7e-07
Identities = 28/89 (31%), Positives = 55/89 (61%), Gaps = 6/89 (6%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQERRKKKE---MEERMSLEETKEQILKLEEKLLAL 79
+ E E K QE+EE + E+K++E++E+ +++E E+ + +E + + EEK+ L
Sbjct: 309 IQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRL 368
Query: 80 QE---EKHQLFLQLKKVLHEEEKRRRKEQ 105
+E EK + +L++ +HE+EK R +E+
Sbjct: 369 EEMMWEKEEKIRELEEKMHEQEKIREQEE 397
Score = 48.9 bits (115), Expect = 6e-06
Identities = 25/83 (30%), Positives = 56/83 (67%), Gaps = 1/83 (1%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEE 82
M E+E K QE+E++ + E+K++E++E+ ++++ + R E+ EQ K+ E+ +QE+
Sbjct: 553 MGEQEEKMQEQEKM-RRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQ 611
Query: 83 KHQLFLQLKKVLHEEEKRRRKEQ 105
+ +++ Q +K+ +EEK + +E+
Sbjct: 612 EEKMWEQEEKMCEQEEKMQEQEE 634
Score = 48.5 bits (114), Expect = 8e-06
Identities = 24/81 (29%), Positives = 53/81 (65%), Gaps = 1/81 (1%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKH 84
E+E K +E+EE+ + E+KM E++E+ +++E R E+ +EQ K+ E+ ++E++
Sbjct: 534 EQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQE-EKIREQEEKIREQKEKIREQEE 592
Query: 85 QLFLQLKKVLHEEEKRRRKEQ 105
+++ Q +K+ +EE + +E+
Sbjct: 593 KIWEQEEKIREQEEMMQEQEE 613
Score = 47.8 bits (112), Expect = 1e-05
Identities = 30/89 (33%), Positives = 59/89 (66%), Gaps = 7/89 (7%)
Query: 23 MMERERKRQEEEEV----DKM--MEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKL 76
M E+E+ R++EE+V +KM E+K++E++E+ ++E + R E+ +EQ K+ E+
Sbjct: 484 MHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQE 543
Query: 77 LALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
+QE++ ++ Q +K + E+EK RR+E+
Sbjct: 544 EMMQEQEEKMGEQEEK-MQEQEKMRRQEE 571
Score = 47.4 bits (111), Expect = 2e-05
Identities = 24/83 (28%), Positives = 56/83 (67%), Gaps = 1/83 (1%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEE 82
M E+E+ R++EE++ + E+K++E++E+ +++E + E+ +EQ ++E+ + E+
Sbjct: 560 MQEQEKMRRQEEKI-REQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQ 618
Query: 83 KHQLFLQLKKVLHEEEKRRRKEQ 105
+ ++ Q +K+ +EEK RR+E+
Sbjct: 619 EEKMCEQEEKMQEQEEKMRRQEE 641
Score = 46.6 bits (109), Expect = 3e-05
Identities = 28/81 (34%), Positives = 52/81 (64%), Gaps = 11/81 (13%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKH 84
E+E KRQEEE K+ EQ+ ++EQE + ++ E+ + E +E+I + E+K+ +E+ H
Sbjct: 394 EQEEKRQEEE---KIREQEKRQEQEAKMWRQEEK---IREQEEKIREQEKKMWRQEEKIH 447
Query: 85 QLFLQLKKVLHEEEKRRRKEQ 105
+ ++ + EEEKR+ +E+
Sbjct: 448 E-----QEKIREEEKRQEQEE 463
Score = 45.4 bits (106), Expect = 7e-05
Identities = 27/82 (32%), Positives = 51/82 (62%), Gaps = 3/82 (3%)
Query: 25 ERERKRQEEEEVDKMMEQK-MKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEK 83
E+E K +E+EE K+ EQ+ M +EQE + ++ E+ E+ + Q K+ E+ ++E+K
Sbjct: 527 EQEEKIREQEE--KIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQK 584
Query: 84 HQLFLQLKKVLHEEEKRRRKEQ 105
++ Q +K+ +EEK R +E+
Sbjct: 585 EKIREQEEKIWEQEEKIREQEE 606
Score = 43.5 bits (101), Expect = 3e-04
Identities = 27/100 (27%), Positives = 54/100 (54%), Gaps = 5/100 (5%)
Query: 6 ERPKLSNAMARALHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEET 65
E K+ R M +E K +E+EE + E+KM ++E+ ++E +
Sbjct: 401 EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQE 460
Query: 66 KEQILKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
+E++ + EEK+ E+ +++ Q K+ +HE+EK R++E+
Sbjct: 461 QEEMWRQEEKI----REQEEIWRQ-KEKMHEQEKIRKQEE 495
Score = 43.1 bits (100), Expect = 3e-04
Identities = 30/95 (31%), Positives = 54/95 (56%), Gaps = 11/95 (11%)
Query: 22 IMMERERKRQEEEEVDKMMEQKMKEEQE-----RRKKKEMEERM-SLEETKEQILKLEEK 75
+M E+E K + +EE+ E+KM+ +E K +E+EE+M E+ +EQ K +E+
Sbjct: 343 MMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEE 402
Query: 76 LLALQEEKHQ-----LFLQLKKVLHEEEKRRRKEQ 105
++EK Q ++ Q +K+ +EEK R +E+
Sbjct: 403 EKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEK 437
Score = 43.1 bits (100), Expect = 3e-04
Identities = 27/91 (29%), Positives = 57/91 (62%), Gaps = 11/91 (12%)
Query: 22 IMMERERK-RQ------EEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEE 74
+M E+E K R+ E+E++ + E++ +EE+ R ++K E+ + +E+I + EE
Sbjct: 371 MMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEE 430
Query: 75 KLLALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
K ++E++ +++ Q +K+ HE+EK R +E+
Sbjct: 431 K---IREQEKKMWRQEEKI-HEQEKIREEEK 457
Score = 43.1 bits (100), Expect = 3e-04
Identities = 27/83 (32%), Positives = 53/83 (63%), Gaps = 8/83 (9%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEE 82
M ++E K +E+EE E+K++E++E K +E EE++ +E++++ +E+ + QEE
Sbjct: 504 MHDQEEKIREQEEKMWRQEEKIREQEE--KIREQEEKI---REQEEMMQEQEEKMGEQEE 558
Query: 83 KHQLFLQLKKVLHEEEKRRRKEQ 105
K Q + +K+ +EEK R +E+
Sbjct: 559 KMQ---EQEKMRRQEEKIREQEE 578
Score = 42.7 bits (99), Expect = 4e-04
Identities = 25/81 (30%), Positives = 48/81 (59%), Gaps = 8/81 (9%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKH 84
E+E K + +EE+ E+KM+ ++E +KE + R +E + + EEK+ L+E+ H
Sbjct: 332 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR----RLEEMMWEKEEKIRELEEKMH 387
Query: 85 QLFLQLKKVLHEEEKRRRKEQ 105
+ +K+ +EEKR+ +E+
Sbjct: 388 ----EQEKIREQEEKRQEEEK 404
Score = 42.4 bits (98), Expect = 6e-04
Identities = 27/87 (31%), Positives = 53/87 (60%), Gaps = 9/87 (10%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETK----EQILKLEEKLLA 78
M +E K +E+EE + E+K++E++E + E EE+M +E K E++ + EEK+
Sbjct: 518 MWRQEEKIREQEEKIREQEEKIREQEEMMQ--EQEEKMGEQEEKMQEQEKMRRQEEKI-- 573
Query: 79 LQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
+E++ ++ Q +K+ +EEK +E+
Sbjct: 574 -REQEEKIREQKEKIREQEEKIWEQEE 599
Score = 41.6 bits (96), Expect = 0.001
Identities = 27/83 (32%), Positives = 52/83 (62%), Gaps = 4/83 (4%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETK--EQILKLEEKLLALQEE 82
E+E K +E++E + E+K+ E++E K +E EE M +E K EQ K+ E+ +QE+
Sbjct: 575 EQEEKIREQKEKIREQEEKIWEQEE--KIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ 632
Query: 83 KHQLFLQLKKVLHEEEKRRRKEQ 105
+ ++ Q +K+ +E + R++E+
Sbjct: 633 EEKMRRQEEKMWEQEVRLRQQEE 655
Score = 40.4 bits (93), Expect = 0.002
Identities = 22/74 (29%), Positives = 46/74 (62%), Gaps = 3/74 (4%)
Query: 32 EEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKHQLFLQLK 91
EE E+ + Q+ +E+ R+++K E ++E +E+I + EEK+ +E++ ++ Q +
Sbjct: 286 EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKI---REQEEKMRRQEE 342
Query: 92 KVLHEEEKRRRKEQ 105
+ +EEK RR+E+
Sbjct: 343 MMWEKEEKMRRQEE 356
Score = 39.7 bits (91), Expect = 0.004
Identities = 24/69 (34%), Positives = 42/69 (60%), Gaps = 7/69 (10%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQER-----RKKKEMEERMSLEETK--EQILKLEEKLL 77
E+E K +E+EE+ + E+KM E++E+ K +E EE+M +E K EQ ++L ++
Sbjct: 596 EQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEE 655
Query: 78 ALQEEKHQL 86
+QE + L
Sbjct: 656 KMQEHQEHL 664
Score = 39.3 bits (90), Expect = 0.005
Identities = 28/98 (28%), Positives = 54/98 (55%), Gaps = 6/98 (6%)
Query: 9 KLSNAMARALHRHIMMERERKRQEEEEVDKMMEQKMKE-EQERRKKKEMEERMSLEETKE 67
KL A + + E + +E + V ++ +++E E R ++ EE+M +E E
Sbjct: 250 KLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQE--E 307
Query: 68 QILKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
+I + EEK+ QE++ ++ Q +K+ +EEK RR+E+
Sbjct: 308 KIQEWEEKI---QEQEEKIREQEEKIREQEEKMRRQEE 342
Score = 39.3 bits (90), Expect = 0.005
Identities = 25/91 (27%), Positives = 57/91 (62%), Gaps = 11/91 (12%)
Query: 23 MMERERKRQEEEEV----DKMMEQ-KMKEEQE---RRKKKEMEERMSLEETKEQILKLEE 74
M +E K +E+EE+ +KM EQ K+++++E R+++K ++ + E +E++ + EE
Sbjct: 464 MWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEE 523
Query: 75 KLLALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
K ++E++ ++ Q +K+ +EE + +E+
Sbjct: 524 K---IREQEEKIREQEEKIREQEEMMQEQEE 551
Score = 38.1 bits (87), Expect = 0.011
Identities = 22/78 (28%), Positives = 46/78 (58%)
Query: 28 RKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKHQLF 87
R Q++EE E+K++E +E+ +++E + R E+ +EQ K+ + + E++ ++
Sbjct: 293 RLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMR 352
Query: 88 LQLKKVLHEEEKRRRKEQ 105
Q + + +EEK RR E+
Sbjct: 353 RQEEMMWEKEEKMRRLEE 370
Score = 37.4 bits (85), Expect = 0.018
Identities = 23/70 (32%), Positives = 42/70 (60%), Gaps = 9/70 (12%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQER---RKKKEMEERMSLEETKEQILKLEEKL----- 76
E+E K E+EE + E+ M+E++E+ +++K E+ ++E +E++ + EEK+
Sbjct: 589 EQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV 648
Query: 77 -LALQEEKHQ 85
L QEEK Q
Sbjct: 649 RLRQQEEKMQ 658
Score = 35.8 bits (81), Expect = 0.053
Identities = 20/60 (33%), Positives = 38/60 (63%), Gaps = 3/60 (5%)
Query: 22 IMMERERKRQEEEEVDKMMEQKMKEEQE---RRKKKEMEERMSLEETKEQILKLEEKLLA 78
+M E+E K E+EE E+KM+E++E R+++K E+ + L + +E++ + +E L A
Sbjct: 607 MMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEA 666
Score = 33.1 bits (74), Expect = 0.35
Identities = 18/70 (25%), Positives = 42/70 (60%), Gaps = 1/70 (1%)
Query: 32 EEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKHQLFLQLK 91
++++ D+ +E+ KE ++ + ++ EE KE+ KL+EKL ++ EK ++ L +K
Sbjct: 187 QKKKADRYIEELTKE-RDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVK 245
Query: 92 KVLHEEEKRR 101
++ + E+ +
Sbjct: 246 ELKRKLERAK 255
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 51.2 bits (121), Expect = 1e-06
Identities = 25/81 (30%), Positives = 53/81 (65%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKH 84
E+E K E+EE E+KM+E++E+ +++E + R ++ +EQ K+ E+ +QE++
Sbjct: 610 EQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEE 669
Query: 85 QLFLQLKKVLHEEEKRRRKEQ 105
+++ Q +K+ +EEK + +E+
Sbjct: 670 KMWEQEEKMCEQEEKMQEQEE 690
Score = 50.1 bits (118), Expect = 3e-06
Identities = 28/94 (29%), Positives = 60/94 (63%), Gaps = 7/94 (7%)
Query: 18 LHRHIMMERERKRQEEEEVDKMMEQKMKEEQE--RRKKKEMEERMSLEETKEQILKLEEK 75
+H + E KRQE+EE+ + E+K++E++E R+K+K E+ + + +E++ + EEK
Sbjct: 507 IHEQEKIREEEKRQEQEEMWR-QEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEK 565
Query: 76 L----LALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
+ ++E++ +++ Q +K+ +EEK R +E+
Sbjct: 566 MHDQEEKIREQEEKVWRQEEKIREQEEKIREQEE 599
Score = 50.1 bits (118), Expect = 3e-06
Identities = 26/83 (31%), Positives = 53/83 (63%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEE 82
M E+E K E+EE + E+KM+ ++E+ +++E + R E+ +EQ ++E+ + E+
Sbjct: 615 MGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQ 674
Query: 83 KHQLFLQLKKVLHEEEKRRRKEQ 105
+ ++ Q +K+ +EEK RR+E+
Sbjct: 675 EEKMCEQEEKMQEQEEKMRRQEE 697
Score = 49.7 bits (117), Expect = 4e-06
Identities = 27/89 (30%), Positives = 54/89 (60%), Gaps = 6/89 (6%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQERRKKKE---MEERMSLEETKEQILKLEEKLLAL 79
+ E E K QE+EE + E+K++E++E+ +++E E+ + +E + + EEK+
Sbjct: 370 IQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQ 429
Query: 80 QE---EKHQLFLQLKKVLHEEEKRRRKEQ 105
+E EK + +L++ +HE+EK R +E+
Sbjct: 430 EEMMWEKEEKIRELEEKMHEQEKIREQEE 458
Score = 48.1 bits (113), Expect = 1e-05
Identities = 25/81 (30%), Positives = 52/81 (64%), Gaps = 4/81 (4%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKH 84
E E K E+E++ + E++ +EE+ R ++K E+ + +E+I + EEK ++E++
Sbjct: 442 ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEK---IREQEE 498
Query: 85 QLFLQLKKVLHEEEKRRRKEQ 105
+++ Q +K+ HE+EK R +E+
Sbjct: 499 KMWRQEEKI-HEQEKIREEEK 518
Score = 48.1 bits (113), Expect = 1e-05
Identities = 29/81 (35%), Positives = 52/81 (64%), Gaps = 11/81 (13%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKH 84
E+E KRQEEE K+ EQ+ ++EQE + ++ E+ + E +E+I + EEK+ +E+ H
Sbjct: 455 EQEEKRQEEE---KIREQEKRQEQEAKMWRQEEK---IREQEEKIREQEEKMWRQEEKIH 508
Query: 85 QLFLQLKKVLHEEEKRRRKEQ 105
+ ++ + EEEKR+ +E+
Sbjct: 509 E-----QEKIREEEKRQEQEE 524
Score = 46.6 bits (109), Expect = 3e-05
Identities = 26/83 (31%), Positives = 53/83 (63%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEE 82
M ++E K +E+EE E+K++E++E+ +++E + R E T+EQ K+ E+ + E+
Sbjct: 566 MHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQ 625
Query: 83 KHQLFLQLKKVLHEEEKRRRKEQ 105
+ ++ Q +K+ +EEK R +E+
Sbjct: 626 EEKMQEQEEKMRRQEEKIREQEK 648
Score = 46.2 bits (108), Expect = 4e-05
Identities = 25/84 (29%), Positives = 51/84 (60%), Gaps = 7/84 (8%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQERRKKKE---MEERMSLEETKEQILKLEEKLLALQE 81
E+E K +E+EE + E+ M E++E+ +++E E+ + +E + + EEK+ L+E
Sbjct: 386 EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEE 445
Query: 82 EKHQLFLQLKKVLHEEEKRRRKEQ 105
+ H + +K+ +EEKR+ +E+
Sbjct: 446 KMH----EQEKIREQEEKRQEEEK 465
Score = 46.2 bits (108), Expect = 4e-05
Identities = 27/82 (32%), Positives = 52/82 (63%), Gaps = 4/82 (4%)
Query: 26 RERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETK--EQILKLEEKLLALQEEK 83
+E K +E+EE + E+K++E++E + E EE+M +E K EQ K++E+ ++ ++
Sbjct: 583 QEEKIREQEEKIREQEEKIREQEEMTQ--EQEEKMGEQEEKMCEQEEKMQEQEEKMRRQE 640
Query: 84 HQLFLQLKKVLHEEEKRRRKEQ 105
++ Q KK+ +EEK R +E+
Sbjct: 641 EKIREQEKKIREQEEKIREQEE 662
Score = 45.4 bits (106), Expect = 7e-05
Identities = 30/95 (31%), Positives = 55/95 (57%), Gaps = 11/95 (11%)
Query: 22 IMMERERKRQEEEEVDKMMEQKMKEEQE-----RRKKKEMEERM-SLEETKEQILKLEEK 75
+M E+E K + +EE+ E+KM+ ++E K +E+EE+M E+ +EQ K +E+
Sbjct: 404 MMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEE 463
Query: 76 LLALQEEKHQ-----LFLQLKKVLHEEEKRRRKEQ 105
++EK Q ++ Q +K+ +EEK R +E+
Sbjct: 464 EKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEE 498
Score = 45.4 bits (106), Expect = 7e-05
Identities = 28/85 (32%), Positives = 53/85 (62%), Gaps = 4/85 (4%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETK--EQILKLEEKLLALQ 80
M E+E K + +EE + E+K++E++E K +E EE M +E K EQ K+ E+ +Q
Sbjct: 629 MQEQEEKMRRQEEKIREQEKKIREQEE--KIREQEEMMQEQEEKMWEQEEKMCEQEEKMQ 686
Query: 81 EEKHQLFLQLKKVLHEEEKRRRKEQ 105
E++ ++ Q +K+ +E + R++E+
Sbjct: 687 EQEEKMRRQEEKMWEQEVRLRQQEE 711
Score = 44.7 bits (104), Expect = 1e-04
Identities = 26/100 (26%), Positives = 53/100 (53%), Gaps = 4/100 (4%)
Query: 6 ERPKLSNAMARALHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEET 65
E K+ R M +E K +E+EE + E+KM ++E+ ++E +
Sbjct: 462 EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQE 521
Query: 66 KEQILKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
+E++ + EEK+ E+ +++ Q +K+ +EEK R++E+
Sbjct: 522 QEEMWRQEEKI----REQEEIWRQKEKIHEQEEKIRKQEE 557
Score = 43.5 bits (101), Expect = 3e-04
Identities = 26/89 (29%), Positives = 53/89 (59%), Gaps = 4/89 (4%)
Query: 21 HIMMERERKRQE----EEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKL 76
H E+ RK++E +EE E+K++E++E+ ++E + R E+ +EQ K+ E+
Sbjct: 546 HEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQE 605
Query: 77 LALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
QE++ ++ Q +K+ +EEK + +E+
Sbjct: 606 EMTQEQEEKMGEQEEKMCEQEEKMQEQEE 634
Score = 42.7 bits (99), Expect = 4e-04
Identities = 28/87 (32%), Positives = 58/87 (66%), Gaps = 9/87 (10%)
Query: 25 ERERK--RQEEE--EVDKMMEQKMKEEQER--RKKKEMEERMSLEETKEQILKLEEKLLA 78
E+E K RQEE+ E +K+ E++ ++EQE R+++++ E+ + KE+I + EEK
Sbjct: 495 EQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEK--- 551
Query: 79 LQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
+++++ +++ Q +K+ +EEK R +E+
Sbjct: 552 IRKQEEKMWRQEEKMHDQEEKIREQEE 578
Score = 42.0 bits (97), Expect = 7e-04
Identities = 25/88 (28%), Positives = 50/88 (56%), Gaps = 4/88 (4%)
Query: 22 IMMERERKRQEEEEVDKMMEQKMKEEQER----RKKKEMEERMSLEETKEQILKLEEKLL 77
+M E+E K + +EE+ E+K++E +E+ K +E EE+ EE + K +E+
Sbjct: 418 MMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEA 477
Query: 78 ALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
+ ++ ++ Q +K+ +EEK R+E+
Sbjct: 478 KMWRQEEKIREQEEKIREQEEKMWRQEE 505
Score = 40.4 bits (93), Expect = 0.002
Identities = 22/74 (29%), Positives = 46/74 (62%), Gaps = 3/74 (4%)
Query: 32 EEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKHQLFLQLK 91
EE E+ + Q+ +E+ R+++K E ++E +E+I + EEK+ +E++ ++ Q +
Sbjct: 347 EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKI---REQEEKMRRQEE 403
Query: 92 KVLHEEEKRRRKEQ 105
+ +EEK RR+E+
Sbjct: 404 MMWEKEEKMRRQEE 417
Score = 39.7 bits (91), Expect = 0.004
Identities = 24/69 (34%), Positives = 42/69 (60%), Gaps = 7/69 (10%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQER-----RKKKEMEERMSLEETK--EQILKLEEKLL 77
E+E K +E+EE+ + E+KM E++E+ K +E EE+M +E K EQ ++L ++
Sbjct: 652 EQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEE 711
Query: 78 ALQEEKHQL 86
+QE + L
Sbjct: 712 KMQEHQEHL 720
Score = 39.3 bits (90), Expect = 0.005
Identities = 28/98 (28%), Positives = 54/98 (55%), Gaps = 6/98 (6%)
Query: 9 KLSNAMARALHRHIMMERERKRQEEEEVDKMMEQKMKE-EQERRKKKEMEERMSLEETKE 67
KL A + + E + +E + V ++ +++E E R ++ EE+M +E E
Sbjct: 311 KLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQE--E 368
Query: 68 QILKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
+I + EEK+ QE++ ++ Q +K+ +EEK RR+E+
Sbjct: 369 KIQEWEEKI---QEQEEKIREQEEKIREQEEKMRRQEE 403
Score = 39.3 bits (90), Expect = 0.005
Identities = 22/78 (28%), Positives = 47/78 (60%)
Query: 28 RKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKHQLF 87
R Q++EE E+K++E +E+ +++E + R E+ +EQ K+ + + E++ ++
Sbjct: 354 RLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMR 413
Query: 88 LQLKKVLHEEEKRRRKEQ 105
Q + + +EEK RR+E+
Sbjct: 414 RQEEMMWEKEEKMRRQEE 431
Score = 39.3 bits (90), Expect = 0.005
Identities = 23/70 (32%), Positives = 44/70 (62%), Gaps = 9/70 (12%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQER---RKKKEMEERMSLEETKEQILKLEEKL----- 76
E+E+K +E+EE + E+ M+E++E+ +++K E+ ++E +E++ + EEK+
Sbjct: 645 EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV 704
Query: 77 -LALQEEKHQ 85
L QEEK Q
Sbjct: 705 RLRQQEEKMQ 714
Score = 36.6 bits (83), Expect = 0.031
Identities = 30/89 (33%), Positives = 52/89 (58%), Gaps = 16/89 (17%)
Query: 25 ERERKRQEE---EEVDKMMEQK-MKEEQERRKKKEMEERMSLEETKEQILKLEEKL---- 76
E + +RQEE E+ +KM Q+ M E+E + +++ E + E +E+I +LEEK+
Sbjct: 395 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEE---MMWEKEEKIRELEEKMHEQE 451
Query: 77 -LALQEEKHQLFLQLKKVLHEEEKRRRKE 104
+ QEEK Q ++ + E+EKR+ +E
Sbjct: 452 KIREQEEKR----QEEEKIREQEKRQEQE 476
Score = 35.8 bits (81), Expect = 0.053
Identities = 20/60 (33%), Positives = 38/60 (63%), Gaps = 3/60 (5%)
Query: 22 IMMERERKRQEEEEVDKMMEQKMKEEQE---RRKKKEMEERMSLEETKEQILKLEEKLLA 78
+M E+E K E+EE E+KM+E++E R+++K E+ + L + +E++ + +E L A
Sbjct: 663 MMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEA 722
Score = 33.1 bits (74), Expect = 0.35
Identities = 18/70 (25%), Positives = 42/70 (60%), Gaps = 1/70 (1%)
Query: 32 EEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKHQLFLQLK 91
++++ D+ +E+ KE ++ + ++ EE KE+ KL+EKL ++ EK ++ L +K
Sbjct: 248 QKKKADRYIEELTKE-RDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVK 306
Query: 92 KVLHEEEKRR 101
++ + E+ +
Sbjct: 307 ELKRKLERAK 316
>gi|154354979 myosin X [Homo sapiens]
Length = 2058
Score = 50.8 bits (120), Expect = 2e-06
Identities = 36/128 (28%), Positives = 73/128 (57%), Gaps = 13/128 (10%)
Query: 3 ALLERPKLSNAMARALHRHIMMER---ERKRQEEEEVDKMMEQKMKEEQERRKKKEMEER 59
A++ + +L +AR ++R ++ E+ E K+++EEE K E++ +E + R++ E+ +
Sbjct: 792 AIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQ 851
Query: 60 MSLEETKEQILKL-----EEKLLALQEEKHQLFLQLKKVLHEEEK----RRRKEQSDLTT 110
E K+Q L+ +E L + EK + Q++++L E++ +R KEQ +L +
Sbjct: 852 QEEETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQEL-S 910
Query: 111 LTSAAYQQ 118
LT A+ Q+
Sbjct: 911 LTEASLQK 918
>gi|92859701 myosin VI [Homo sapiens]
Length = 1285
Score = 50.4 bits (119), Expect = 2e-06
Identities = 52/172 (30%), Positives = 81/172 (47%), Gaps = 21/172 (12%)
Query: 5 LERPKLSNAMARALHR-HIMMERERKRQEEEEVDKMMEQ---KMKEEQERRKKKEMEERM 60
L++ K A L R ME+ERKR+EE+E + E+ +MK E E ++K+E EER
Sbjct: 913 LQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAKRKQEEEERK 972
Query: 61 SLEETKEQILKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQSDLTTLTSAAYQQSL 120
E+ +++I E LA Q+E+ Q + VL +E + R L A + L
Sbjct: 973 KREDDEKRIQAEVEAQLARQKEEES---QQQAVLEQERRDRE------LALRIAQSEAEL 1023
Query: 121 TVHTGTHLLSMQGSPGGHNRPGTLMAADRAKQMF-----GPQVLTTRHYVGS 167
L+++ + G RP + AK+M GP VL T+ G+
Sbjct: 1024 ISDEAQADLALRRNDG--TRP-KMTPEQMAKEMSEFLSRGPAVLATKAAAGT 1072
Score = 39.3 bits (90), Expect = 0.005
Identities = 20/86 (23%), Positives = 47/86 (54%), Gaps = 3/86 (3%)
Query: 22 IMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQE 81
I E + + EE+ +++K ++E+E + + ++E M E + + +EK +E
Sbjct: 895 IQKEYDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRRE---EDEKRRRKEE 951
Query: 82 EKHQLFLQLKKVLHEEEKRRRKEQSD 107
E+ ++ L+++ +EE+ R+K + D
Sbjct: 952 EERRMKLEMEAKRKQEEEERKKREDD 977
Score = 35.4 bits (80), Expect = 0.070
Identities = 23/69 (33%), Positives = 38/69 (55%), Gaps = 4/69 (5%)
Query: 39 MMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKHQLFLQLKKVLHEEE 98
MM Q+ +++ K EE +S + K+Q + E+L +QEE + +K E+E
Sbjct: 889 MMTQEQIQKEYDALVKSSEELLSALQKKKQQEEEAERLRRIQEEME----KERKRREEDE 944
Query: 99 KRRRKEQSD 107
KRRRKE+ +
Sbjct: 945 KRRRKEEEE 953
>gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo
sapiens]
Length = 956
Score = 50.4 bits (119), Expect = 2e-06
Identities = 32/89 (35%), Positives = 55/89 (61%), Gaps = 5/89 (5%)
Query: 24 MERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETK---EQILKLEEKLLALQ 80
++ E KR +EE K E+K +E+ERR+K+E +E+ E+ + E+ + +E L A
Sbjct: 360 LKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKL 419
Query: 81 EEKHQLFLQLKKVLHEEEKRRRKEQSDLT 109
EEK + + +K L EEEKR + E++++T
Sbjct: 420 EEKRK--KEEEKRLREEEKRIKAEKAEIT 446
Score = 39.7 bits (91), Expect = 0.004
Identities = 17/65 (26%), Positives = 44/65 (67%), Gaps = 1/65 (1%)
Query: 23 MMERERK-RQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQE 81
+ E+ER+ ++E++E +K +Q++KEE+ + +++ +E ++ + KE+ +L E+ ++
Sbjct: 381 LKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKA 440
Query: 82 EKHQL 86
EK ++
Sbjct: 441 EKAEI 445
Score = 36.2 bits (82), Expect = 0.041
Identities = 26/97 (26%), Positives = 55/97 (56%), Gaps = 10/97 (10%)
Query: 22 IMMERERKR---QEEEEVDKMMEQKMKEE-----QERRKKKEMEERMSLEETKEQILKLE 73
+ ++R+++R Q + ++ ++K+KEE +E +KKKE E+ + +E +E+ K E
Sbjct: 335 LRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDE 394
Query: 74 EKLLALQEEKHQLFLQLKKVLHE--EEKRRRKEQSDL 108
++ Q K + + ++ L EEKR+++E+ L
Sbjct: 395 KEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRL 431
Score = 30.4 bits (67), Expect = 2.2
Identities = 16/51 (31%), Positives = 34/51 (66%), Gaps = 3/51 (5%)
Query: 16 RALHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETK 66
+A + + ER ++RQ E ++ +E+K K+E+E+R ++E E+R+ E+ +
Sbjct: 397 KAEKQRLKEERRKERQ--EALEAKLEEKRKKEEEKRLREE-EKRIKAEKAE 444
Score = 28.5 bits (62), Expect = 8.5
Identities = 19/80 (23%), Positives = 42/80 (52%), Gaps = 2/80 (2%)
Query: 43 KMKEEQERRKK--KEMEERMSLEETKEQILKLEEKLLALQEEKHQLFLQLKKVLHEEEKR 100
+++ +QER K K ER E+ KE+ + +E+ +EE+ +L + ++ E++++
Sbjct: 336 RLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEK 395
Query: 101 RRKEQSDLTTLTSAAYQQSL 120
+ E+ L Q++L
Sbjct: 396 EKAEKQRLKEERRKERQEAL 415
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 50.1 bits (118), Expect = 3e-06
Identities = 26/83 (31%), Positives = 53/83 (63%), Gaps = 2/83 (2%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKH 84
E E +R+EEEE ++ E+ +EE+ER++++E EE+ +E +E+ K +EK +EK
Sbjct: 2246 EEEEEREEEEEREE--EEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKE 2303
Query: 85 QLFLQLKKVLHEEEKRRRKEQSD 107
++F + ++++ EEE ++ +
Sbjct: 2304 EVFEEKEEIMSEEETESLSDEEE 2326
Score = 47.0 bits (110), Expect = 2e-05
Identities = 29/84 (34%), Positives = 52/84 (61%), Gaps = 4/84 (4%)
Query: 25 ERERKRQEEEE---VDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQE 81
E ERK +EE E V+K E+K K+++E+ KK+E++E+ + E KE+I+ EE E
Sbjct: 2266 EEERKEEEEGEEKQVEKEEEEKKKKKKEK-KKEEVQEKEEVFEEKEEIMSEEETESLSDE 2324
Query: 82 EKHQLFLQLKKVLHEEEKRRRKEQ 105
E+ + L++ + E++ +KE+
Sbjct: 2325 EEEEESCSLEEEVDREKEILKKEK 2348
Score = 45.1 bits (105), Expect = 9e-05
Identities = 40/144 (27%), Positives = 70/144 (48%), Gaps = 11/144 (7%)
Query: 6 ERPKLSNAM-ARALHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERM---- 60
E+ KL+ A A R + E E K +EEE+ ++++K K Q + K E EER+
Sbjct: 1745 EKKKLAEEEEALAWQREKLSEEETKLAQEEEL--LIQEKEKLAQHKEKMPEEEERLGRKR 1802
Query: 61 -SLEETKEQILKLEEKLLALQEE--KHQLFLQLKKVLHEEEKRRRKEQSDLT-TLTSAAY 116
L E K ++ + E+ + EE K+++ L KK L +E+K +E+ L + Y
Sbjct: 1803 EQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLY 1862
Query: 117 QQSLTVHTGTHLLSMQGSPGGHNR 140
+ H+ L+ ++ G N+
Sbjct: 1863 NKERLTHSKKQLVQVKNKLGMFNK 1886
Score = 40.0 bits (92), Expect = 0.003
Identities = 32/86 (37%), Positives = 49/86 (56%), Gaps = 10/86 (11%)
Query: 24 MERERKRQEE--EEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQE 81
ME ++EE +E K++E+K K +E E++S EETK L EE+LL ++
Sbjct: 1725 MEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETK---LAQEEELLIQEK 1781
Query: 82 EKHQLFLQLKKVLHEEEKR--RRKEQ 105
EK Q K+ + EEE+R R++EQ
Sbjct: 1782 EK---LAQHKEKMPEEEERLGRKREQ 1804
Score = 37.0 bits (84), Expect = 0.024
Identities = 24/81 (29%), Positives = 47/81 (58%), Gaps = 7/81 (8%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKH 84
E E + EE++ ++++ E+QE +E EER EE +E+ ++ EE+ +EE
Sbjct: 2219 EVESEEHFSEEMESLLDE--LEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGE 2276
Query: 85 QLFLQLKKVLHEEEKRRRKEQ 105
+ K+V EEE++++K++
Sbjct: 2277 E-----KQVEKEEEEKKKKKK 2292
Score = 36.2 bits (82), Expect = 0.041
Identities = 25/92 (27%), Positives = 46/92 (50%), Gaps = 7/92 (7%)
Query: 21 HIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKE-------QILKLE 73
H E E E E+ + + ++ +E +E +++E E R EE KE Q+ K E
Sbjct: 2225 HFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEE 2284
Query: 74 EKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
E+ ++EK + +Q K+ + EE++ E+
Sbjct: 2285 EEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEE 2316
Score = 35.8 bits (81), Expect = 0.053
Identities = 25/89 (28%), Positives = 45/89 (50%), Gaps = 9/89 (10%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKE----EQERRKKKEMEERMSLEETKEQILKLEEKLLA 78
+ R RKR+E + DK E+ + E E +EME + E +E + EE+
Sbjct: 2193 LKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEERE 2252
Query: 79 LQEEKHQLFLQLKKVLHEEEKRRRKEQSD 107
+EE+ + ++V EEE+R+ +E+ +
Sbjct: 2253 EEEEREE-----EEVREEEEERKEEEEGE 2276
Score = 35.8 bits (81), Expect = 0.053
Identities = 26/78 (33%), Positives = 48/78 (61%), Gaps = 9/78 (11%)
Query: 25 ERERKRQEEEEVDKMMEQK---MKEEQER--RKKKEMEERMSLEE---TKEQILKLEEKL 76
++E+K++E +E +++ E+K M EE+ ++E EE SLEE +++ILK +EK
Sbjct: 2291 KKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILK-KEKQ 2349
Query: 77 LALQEEKHQLFLQLKKVL 94
LQE++ + ++VL
Sbjct: 2350 FKLQEQRRKSLRGRERVL 2367
Score = 35.0 bits (79), Expect = 0.091
Identities = 24/95 (25%), Positives = 50/95 (52%), Gaps = 4/95 (4%)
Query: 14 MARALHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLE----ETKEQI 69
+AR I+ + E EEEEV ++++ ++ +E ++ + +E+ S + E++E
Sbjct: 2167 LARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHF 2226
Query: 70 LKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKE 104
+ E LL E++ L + ++ EEE+R +E
Sbjct: 2227 SEEMESLLDELEKQESLSSEEEEEREEEEEREEEE 2261
Score = 33.9 bits (76), Expect = 0.20
Identities = 30/107 (28%), Positives = 57/107 (53%), Gaps = 8/107 (7%)
Query: 4 LLERPKLSNAMARALHRHIMMERERKRQEEEEV---DKMMEQKMKEEQERRKKK-EMEER 59
L E KL A + M++ ++K + EE + M+ K KE+Q + +++ +EE
Sbjct: 1490 LQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEE 1549
Query: 60 MSLE-ETKEQILKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
+S E E KEQ + E++ + +E+H+ +K E+KR ++E+
Sbjct: 1550 VSREGEEKEQQVTEEQRHI---QEEHKWARIHRKRARAEKKRAQEER 1593
Score = 32.7 bits (73), Expect = 0.45
Identities = 29/106 (27%), Positives = 50/106 (47%), Gaps = 11/106 (10%)
Query: 6 ERPKLSNAMARALHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEME---ERMSL 62
E K A + ++ E E+ Q E++ E++M +E ++ K +E + E M
Sbjct: 1473 ETRKSWKAWKEEWEKRLLQEEEKLHQAGEKLSP--EEEMLQEDKKLKWEEWKQVWENMLS 1530
Query: 63 EETKEQILK------LEEKLLALQEEKHQLFLQLKKVLHEEEKRRR 102
++KEQ K LEE++ EEK Q + ++ + EE K R
Sbjct: 1531 SKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWAR 1576
Score = 32.7 bits (73), Expect = 0.45
Identities = 28/125 (22%), Positives = 58/125 (46%), Gaps = 8/125 (6%)
Query: 6 ERPKLSNAMARALHRHIMMERERKRQEEE-----EVDKMMEQKMKEEQERRKKKEMEERM 60
E KL+ + + + RE ++ ++ EV ++ QK++E +R + + +E+
Sbjct: 1654 EAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKE 1713
Query: 61 SLEETKEQILKLEE---KLLALQEEKHQLFLQLKKVLHEEEKRRRKEQSDLTTLTSAAYQ 117
+E +E +EE K L +E+ +L + KK+ EEE + + T A +
Sbjct: 1714 LAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQE 1773
Query: 118 QSLTV 122
+ L +
Sbjct: 1774 EELLI 1778
Score = 32.7 bits (73), Expect = 0.45
Identities = 26/104 (25%), Positives = 55/104 (52%), Gaps = 12/104 (11%)
Query: 40 MEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEE--KHQLFLQLKKVLHEE 97
+E+K+ +E+E KK+ + L ET+++++++E+ L QE+ + ++ L L+K + +
Sbjct: 1891 VEEKLTQEKETVIKKKEK----LAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQG 1946
Query: 98 EKRRR------KEQSDLTTLTSAAYQQSLTVHTGTHLLSMQGSP 135
+KR R KE+ L ++ + + G LS +P
Sbjct: 1947 KKRLRGELDIAKEEKALNLEMKRLAEEKMRLVEGKETLSKGETP 1990
Score = 32.3 bits (72), Expect = 0.59
Identities = 24/90 (26%), Positives = 47/90 (52%), Gaps = 6/90 (6%)
Query: 20 RHIMMERERKRQEE----EEVDKMMEQKMKEEQERRKKKEMEERMSLEETK--EQILKLE 73
R + E E+ QEE +E K+ + +K Q+ R+ + E + + +E ++ KL
Sbjct: 1593 RKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLS 1652
Query: 74 EKLLALQEEKHQLFLQLKKVLHEEEKRRRK 103
++ L +++ +L + +KV EEEK +K
Sbjct: 1653 QEAEKLAQKRKKLAKKWEKVAREEEKLAKK 1682
Score = 31.2 bits (69), Expect = 1.3
Identities = 28/108 (25%), Positives = 55/108 (50%), Gaps = 14/108 (12%)
Query: 3 ALLERPKLSNAMARALHRHIMMERERKRQEEEEVDKMM------EQKMKEEQERRKKKEM 56
+L + P N + +AL + ER + QEE ++ KM E+++ EQ + KE
Sbjct: 2065 SLSKEPAKLNKILKALQKLTRDER-KLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEW 2123
Query: 57 EERMSLEETKEQILKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKE 104
+ E + ++ K E+KL Q + L ++++++++EEK +E
Sbjct: 2124 D----FSEKRSELTKDEKKLARKQRK---LANKMRRMINKEEKMTEEE 2164
Score = 30.4 bits (67), Expect = 2.2
Identities = 28/100 (28%), Positives = 53/100 (53%), Gaps = 15/100 (15%)
Query: 22 IMMERERKRQ-EEEEVDKMMEQKMKEEQER-----RKKKEMEERMSLEETK----EQILK 71
+ +E E R+ EE+E EQ+ +E+ + RK+ E++ + EE K E+ L
Sbjct: 1544 VTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLA 1603
Query: 72 LEEKLLALQEEK-HQLFLQL----KKVLHEEEKRRRKEQS 106
EE+ LA +E K Q ++++ +++ E K +KE++
Sbjct: 1604 QEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEET 1643
Score = 30.0 bits (66), Expect = 2.9
Identities = 19/61 (31%), Positives = 36/61 (59%), Gaps = 6/61 (9%)
Query: 22 IMMERERKR---QEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLA 78
IM E E + +EEEE +E+++ E+E KK E++ L+E + + L+ E++L+
Sbjct: 2312 IMSEEETESLSDEEEEEESCSLEEEVDREKEILKK---EKQFKLQEQRRKSLRGRERVLS 2368
Query: 79 L 79
+
Sbjct: 2369 I 2369
Score = 29.3 bits (64), Expect = 5.0
Identities = 18/50 (36%), Positives = 31/50 (62%), Gaps = 5/50 (10%)
Query: 31 QEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQ 80
Q+E +V K+ + KE ER +E+EE +LE E+++K E KL+ ++
Sbjct: 1408 QKERKVGKIKREMTKE--ERDMSEEVEEMATLE---EKVVKQEGKLVMIE 1452
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 50.1 bits (118), Expect = 3e-06
Identities = 62/234 (26%), Positives = 102/234 (43%), Gaps = 32/234 (13%)
Query: 5 LERPKLSNAMARALHRHIMMER-ERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLE 63
LER +L R + ER ER+R E E +++ ++ ++E+ER+++ E +ER+ +
Sbjct: 156 LERERLERE--RMERERLERERLERERLERERLEQEQLERERQERERQERLERQERLERQ 213
Query: 64 ETKEQILKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQSDLTTL--------TSAA 115
E E+ +L+ + QE + +L+++ E ++R R+EQ + L +SAA
Sbjct: 214 ERLERQERLDRERQERQERE-----RLERLERERQERERQEQLEREQLEWERERRISSAA 268
Query: 116 YQQSLTVHTGTHLLSMQGSPGGHNRPGTLMAADRAKQMFGPQVLTTRHYVGSAAAFAGTP 175
S+ T L S+ G + PG L AA + + Q + +G A P
Sbjct: 269 APASVE----TPLNSVLGDSSA-SEPG-LQAASQPAETPSQQGIV----LGPLAPPPPPP 318
Query: 176 EHGQFQGSPGGAYGTAQPPPHYGPTQPAYSPSQQLRAPSAFPAVQYLSQPQPQP 229
PG A + PP GP P PS P P + P P P
Sbjct: 319 L------PPGPAQASVALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQVPPPPPP 366
Score = 38.1 bits (87), Expect = 0.011
Identities = 23/85 (27%), Positives = 52/85 (61%), Gaps = 2/85 (2%)
Query: 24 MERERKRQEEEEVDKMMEQKMKEEQERRKKKEME-ERMSLEETKEQILKLEEKLLALQEE 82
+E +R++ +E++ K +E++ + E+ER +++ +E ER+ E + + L+ E+ QE
Sbjct: 140 LEIQRRQLQEQQRQKELERE-RLERERMERERLERERLERERLERERLEQEQLERERQER 198
Query: 83 KHQLFLQLKKVLHEEEKRRRKEQSD 107
+ Q L+ ++ L +E+ R+E+ D
Sbjct: 199 ERQERLERQERLERQERLERQERLD 223
Score = 28.5 bits (62), Expect = 8.5
Identities = 16/75 (21%), Positives = 39/75 (52%), Gaps = 2/75 (2%)
Query: 31 QEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKHQLFLQL 90
QEE E+ + Q+ + ++E +++ ERM E + + +LE + L + + + +
Sbjct: 137 QEELEIQRRQLQEQQRQKELERERLERERMERERLERE--RLERERLERERLEQEQLERE 194
Query: 91 KKVLHEEEKRRRKEQ 105
++ +E+ R+E+
Sbjct: 195 RQERERQERLERQER 209
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 50.1 bits (118), Expect = 3e-06
Identities = 62/234 (26%), Positives = 102/234 (43%), Gaps = 32/234 (13%)
Query: 5 LERPKLSNAMARALHRHIMMER-ERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLE 63
LER +L R + ER ER+R E E +++ ++ ++E+ER+++ E +ER+ +
Sbjct: 156 LERERLERE--RMERERLERERLERERLERERLEQEQLERERQERERQERLERQERLERQ 213
Query: 64 ETKEQILKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQSDLTTL--------TSAA 115
E E+ +L+ + QE + +L+++ E ++R R+EQ + L +SAA
Sbjct: 214 ERLERQERLDRERQERQERE-----RLERLERERQERERQEQLEREQLEWERERRISSAA 268
Query: 116 YQQSLTVHTGTHLLSMQGSPGGHNRPGTLMAADRAKQMFGPQVLTTRHYVGSAAAFAGTP 175
S+ T L S+ G + PG L AA + + Q + +G A P
Sbjct: 269 APASVE----TPLNSVLGDSSA-SEPG-LQAASQPAETPSQQGIV----LGPLAPPPPPP 318
Query: 176 EHGQFQGSPGGAYGTAQPPPHYGPTQPAYSPSQQLRAPSAFPAVQYLSQPQPQP 229
PG A + PP GP P PS P P + P P P
Sbjct: 319 L------PPGPAQASVALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQVPPPPPP 366
Score = 38.1 bits (87), Expect = 0.011
Identities = 23/85 (27%), Positives = 52/85 (61%), Gaps = 2/85 (2%)
Query: 24 MERERKRQEEEEVDKMMEQKMKEEQERRKKKEME-ERMSLEETKEQILKLEEKLLALQEE 82
+E +R++ +E++ K +E++ + E+ER +++ +E ER+ E + + L+ E+ QE
Sbjct: 140 LEIQRRQLQEQQRQKELERE-RLERERMERERLERERLERERLERERLEQEQLERERQER 198
Query: 83 KHQLFLQLKKVLHEEEKRRRKEQSD 107
+ Q L+ ++ L +E+ R+E+ D
Sbjct: 199 ERQERLERQERLERQERLERQERLD 223
Score = 28.5 bits (62), Expect = 8.5
Identities = 16/75 (21%), Positives = 39/75 (52%), Gaps = 2/75 (2%)
Query: 31 QEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKHQLFLQL 90
QEE E+ + Q+ + ++E +++ ERM E + + +LE + L + + + +
Sbjct: 137 QEELEIQRRQLQEQQRQKELERERLERERMERERLERE--RLERERLERERLEQEQLERE 194
Query: 91 KKVLHEEEKRRRKEQ 105
++ +E+ R+E+
Sbjct: 195 RQERERQERLERQER 209
>gi|22035606 mitogen-activated protein kinase kinase kinase kinase 4
isoform 3 [Homo sapiens]
Length = 1212
Score = 50.1 bits (118), Expect = 3e-06
Identities = 64/279 (22%), Positives = 112/279 (40%), Gaps = 76/279 (27%)
Query: 20 RHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLAL 79
R ++ ER+++ ++++E + +E++ + E+E R+++E E+R +E K ++ +LE +
Sbjct: 389 RQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKE- 447
Query: 80 QEEKHQLFLQLKKVLHEEEKRRR---KEQSDLTTLTSAAYQ-QSLTVHTGTHLLSMQGSP 135
+EE+ + + ++V E+E RR +EQ L L Q Q++ +H
Sbjct: 448 EEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAMLLH------------ 495
Query: 136 GGHNRPGTLMAADRAKQMFGPQVLTTRHYVGSAAAFAGTPEHGQFQGSPGGAYGTAQPPP 195
H RP P+H Q QPPP
Sbjct: 496 -DHRRP--------------------------------HPQHSQ------------QPPP 510
Query: 196 HYGPTQPAYSPSQQLRAPSAFPAVQYLSQPQPQPYAVHGHFQPTQTGFLQPGGALSLQKQ 255
P Q PS AP P Y +P + V F+ T + + KQ
Sbjct: 511 ---PQQERSKPS--FHAPE--PKAHY--EPADRAREVEDRFRKTNHSSPE-----AQSKQ 556
Query: 256 MEHANQQTGFSDSSSLRPMHPQALHPAPGLLASPQLPVQ 294
+ S S S + +++HPA A PQ+PV+
Sbjct: 557 TGRVLEPPVPSRSESFSNGNSESVHPALQRPAEPQVPVR 595
Score = 47.0 bits (110), Expect = 2e-05
Identities = 30/97 (30%), Positives = 55/97 (56%), Gaps = 5/97 (5%)
Query: 6 ERPKLSNAMARALHRHIMMERERKRQEEEEVDKM--MEQKMKEEQERRKKKEMEERMSLE 63
+R +L R ERE++R+E+EE ++ +E++ KEE+ERR+ + EE+ +E
Sbjct: 405 QRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAE--EEKRRVE 462
Query: 64 ETKEQILK-LEEKLLALQEEKHQLFLQLKKVLHEEEK 99
+E I + LEE+ L+ + QL + +LH+ +
Sbjct: 463 REQEYIRRQLEEEQRHLEVLQQQLLQEQAMLLHDHRR 499
Score = 28.9 bits (63), Expect = 6.5
Identities = 24/118 (20%), Positives = 50/118 (42%), Gaps = 23/118 (19%)
Query: 24 MERERKRQEEEEVDKMMEQKMKEEQERRKKKE-----------------------MEERM 60
++R RK++ E++ + +EE+E ++E E +
Sbjct: 306 IDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKE 365
Query: 61 SLEETKEQILKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQSDLTTLTSAAYQQ 118
E + Q L E++L +E K QL + +K + +++++RR+ + A QQ
Sbjct: 366 RSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQ 423
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 49.7 bits (117), Expect = 4e-06
Identities = 28/86 (32%), Positives = 56/86 (65%), Gaps = 6/86 (6%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQERRKKKE---MEERMSLEETKEQILKLEEKLLAL 79
M E+E + +E+EE + E++M+E++E+ K+E E++ + E KEQ+ K EE+ +
Sbjct: 298 MREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQ---M 354
Query: 80 QEEKHQLFLQLKKVLHEEEKRRRKEQ 105
E++ Q+ Q ++V +EE+ R++E+
Sbjct: 355 GEQEEQMQKQEEQVRKQEEQMRKQEE 380
Score = 47.0 bits (110), Expect = 2e-05
Identities = 26/83 (31%), Positives = 51/83 (61%), Gaps = 6/83 (7%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQERRKKKEM--EERMSLEETKEQILKLEEKLLALQEE 82
+ E+ ++EE+V K EQ K+E++ RK++E E+ + E +EQ+LK +E+ E+
Sbjct: 232 QEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQT----EQ 287
Query: 83 KHQLFLQLKKVLHEEEKRRRKEQ 105
+ Q Q +++ +EE+ R +E+
Sbjct: 288 EEQTGEQEEQMREQEEQMREQEE 310
Score = 45.8 bits (107), Expect = 5e-05
Identities = 27/99 (27%), Positives = 58/99 (58%), Gaps = 5/99 (5%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQERRKKKEM---EERMSLEETKEQILKLEEKLLAL 79
M E+E + E+EE + E++M E++E+ +K+E E+ +++ +EQ+ K EE++
Sbjct: 201 MGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQ 260
Query: 80 QEEKHQLFLQLKKVLHEEEKRRRKEQSDLTTLTSAAYQQ 118
+E+ + Q+++ EE+ ++KEQ++ T +Q
Sbjct: 261 EEQMREQEEQMRE--QEEQMLKQKEQTEQEEQTGEQEEQ 297
Score = 44.3 bits (103), Expect = 2e-04
Identities = 21/81 (25%), Positives = 53/81 (65%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKH 84
E+E + E+EE + E++M+E++E+ +++E + R E+ +Q ++ E+ + E+K
Sbjct: 286 EQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKE 345
Query: 85 QLFLQLKKVLHEEEKRRRKEQ 105
Q++ Q +++ +EE+ +++E+
Sbjct: 346 QMWKQEEQMGEQEEQMQKQEE 366
Score = 43.5 bits (101), Expect = 3e-04
Identities = 20/82 (24%), Positives = 53/82 (64%)
Query: 24 MERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEK 83
M +++++ E+EE E++M+E++E+ +++E + R E+ +EQ ++ ++ + E+K
Sbjct: 278 MLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQK 337
Query: 84 HQLFLQLKKVLHEEEKRRRKEQ 105
Q++ Q +++ +EE+ +E+
Sbjct: 338 EQMWEQKEQMWKQEEQMGEQEE 359
Score = 43.1 bits (100), Expect = 3e-04
Identities = 20/83 (24%), Positives = 54/83 (65%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEE 82
M ++E + E+EE + E+++++++E+ +K+E + R E+ ++Q ++ E+ + E+
Sbjct: 347 MWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQ 406
Query: 83 KHQLFLQLKKVLHEEEKRRRKEQ 105
K Q+ Q +++ ++E+ R++E+
Sbjct: 407 KEQMREQEEQMGEQKEQMRKQEE 429
Score = 42.0 bits (97), Expect = 7e-04
Identities = 25/86 (29%), Positives = 53/86 (61%), Gaps = 5/86 (5%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQER---RKKKEMEERMSLEETKEQILKLEEKLLAL 79
M E+E + +E+EE E++M E++E+ +K++ ++ + E +EQ+ K EE++
Sbjct: 312 MREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQ 371
Query: 80 QEEKHQLFLQLKKVLHEEEKRRRKEQ 105
+E+ + Q++K EE+ R+++EQ
Sbjct: 372 EEQMRKQEEQMRK--QEEQMRKQEEQ 395
Score = 41.2 bits (95), Expect = 0.001
Identities = 24/105 (22%), Positives = 59/105 (56%), Gaps = 5/105 (4%)
Query: 6 ERPKLSNAMARALHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEM-EERMSLEE 64
E+ + R + + E+ R++EE++ K EQ +EEQ ++++M E+ + E
Sbjct: 248 EQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMRE 307
Query: 65 TKEQILKLEEKLLALQE----EKHQLFLQLKKVLHEEEKRRRKEQ 105
+EQ+ + EE++ +E ++ Q++ Q +++ ++E+ ++E+
Sbjct: 308 QEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEE 352
Score = 40.8 bits (94), Expect = 0.002
Identities = 23/89 (25%), Positives = 53/89 (59%), Gaps = 6/89 (6%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKE------EQERRKKKEMEERMSLEETKEQILKLEEKL 76
+ ++E + Q++EE + E++M+E EQE + K+ E+ E+T EQ ++ E+
Sbjct: 243 VQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQE 302
Query: 77 LALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
++E++ Q+ Q +++ +EE+ ++E+
Sbjct: 303 EQMREQEEQMREQEEQMREQEEQMGKQEE 331
Score = 40.4 bits (93), Expect = 0.002
Identities = 22/86 (25%), Positives = 53/86 (61%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEE 82
M E+E + E+EE E++M++++E+ ++E + R E+ EQ +++++ +Q++
Sbjct: 194 MGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQ 253
Query: 83 KHQLFLQLKKVLHEEEKRRRKEQSDL 108
+ Q+ Q +++ +EE+ R +E+ L
Sbjct: 254 EEQMRKQEEQMREQEEQMREQEEQML 279
Score = 39.7 bits (91), Expect = 0.004
Identities = 27/84 (32%), Positives = 48/84 (57%), Gaps = 7/84 (8%)
Query: 25 ERERKRQEE---EEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQE 81
E + +QEE E+ ++M EQK + ++ + E EE+M +E EQ+ K EE++ +E
Sbjct: 323 EEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQE--EQVRKQEEQMRKQEE 380
Query: 82 EKHQLFLQLKKVLHEEEKRRRKEQ 105
+ + Q++K EE+ +KEQ
Sbjct: 381 QMRKQEEQMRK--QEEQMGEQKEQ 402
Score = 38.5 bits (88), Expect = 0.008
Identities = 24/80 (30%), Positives = 50/80 (62%), Gaps = 5/80 (6%)
Query: 26 RERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKHQ 85
RE++ Q E+ +M EQ+ + ++ + ++ EE+M E +EQ+ K EE++ E++ Q
Sbjct: 188 REQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMG--EQEEQMRKQEEQM---GEQEEQ 242
Query: 86 LFLQLKKVLHEEEKRRRKEQ 105
+ Q ++V +EE+ R++E+
Sbjct: 243 VQKQEEQVQKQEEQMRKQEE 262
Score = 37.7 bits (86), Expect = 0.014
Identities = 21/84 (25%), Positives = 52/84 (61%), Gaps = 1/84 (1%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEE 82
M E++ + ++EE E++M++++E+ +K+E + R E+ ++Q ++ ++ + E+
Sbjct: 340 MWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQ 399
Query: 83 KHQLFLQLKKVLHEEEKR-RRKEQ 105
K Q+ Q +++ +EE+ +KEQ
Sbjct: 400 KEQMGEQKEQMREQEEQMGEQKEQ 423
Score = 37.0 bits (84), Expect = 0.024
Identities = 21/79 (26%), Positives = 50/79 (63%), Gaps = 6/79 (7%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQERRKKKEM---EERMSLEETKEQILKLEEKLLAL 79
M ++E + +++EE + E++M++++E+ +K+E E++ + E KEQ+ + EE+ +
Sbjct: 361 MQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQ---M 417
Query: 80 QEEKHQLFLQLKKVLHEEE 98
E+K Q+ Q + + ++E
Sbjct: 418 GEQKEQMRKQEEHMGEQKE 436
Score = 34.3 bits (77), Expect = 0.16
Identities = 22/80 (27%), Positives = 49/80 (61%), Gaps = 5/80 (6%)
Query: 26 RERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKHQ 85
RE++ Q E+ ++ EQ+ + ++ + E EE+M E +EQ+ K EE++ E++ Q
Sbjct: 174 REQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMG--EQEEQMQKQEEQM---GEQEEQ 228
Query: 86 LFLQLKKVLHEEEKRRRKEQ 105
+ Q +++ +EE+ +++E+
Sbjct: 229 MRKQEEQMGEQEEQVQKQEE 248
Score = 31.2 bits (69), Expect = 1.3
Identities = 18/81 (22%), Positives = 49/81 (60%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKH 84
E+E + +E+E + E +++E++ + +++E + R + EQ ++ E+ + E++
Sbjct: 154 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEE 213
Query: 85 QLFLQLKKVLHEEEKRRRKEQ 105
Q+ Q +++ +EE+ R++E+
Sbjct: 214 QMQKQEEQMGEQEEQMRKQEE 234
Score = 30.4 bits (67), Expect = 2.2
Identities = 17/81 (20%), Positives = 50/81 (61%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKH 84
E+E + +E+E + E +++E++ + +++E + R + +EQ ++ E+ + E++
Sbjct: 140 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEG 199
Query: 85 QLFLQLKKVLHEEEKRRRKEQ 105
Q+ Q +++ +EE+ +++E+
Sbjct: 200 QMGEQEEQMGEQEEQMQKQEE 220
Score = 29.3 bits (64), Expect = 5.0
Identities = 15/66 (22%), Positives = 37/66 (56%)
Query: 43 KMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRR 102
++ E+ + K E++E + L ET++ ++L K L + E ++ L + + E+E + R
Sbjct: 3 RITNEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVR 62
Query: 103 KEQSDL 108
+++ +
Sbjct: 63 EQEGQV 68
Score = 29.3 bits (64), Expect = 5.0
Identities = 17/81 (20%), Positives = 48/81 (59%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKH 84
E+E + +E+E + E +++E++ + +++E + R + +EQ ++ E+ + E++
Sbjct: 147 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEE 206
Query: 85 QLFLQLKKVLHEEEKRRRKEQ 105
Q+ Q +++ +EE+ +E+
Sbjct: 207 QMGEQEEQMQKQEEQMGEQEE 227
Score = 28.5 bits (62), Expect = 8.5
Identities = 20/84 (23%), Positives = 49/84 (58%), Gaps = 5/84 (5%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQERRKKKE---MEERMSLEETKEQILKLEEKLLALQE 81
E+E + +E+E + E +++E++ + +++E E+ + E +EQ+ + EE++ +E
Sbjct: 161 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEE 220
Query: 82 EKHQLFLQLKKVLHEEEKRRRKEQ 105
+ + Q++K EE+ ++EQ
Sbjct: 221 QMGEQEEQMRK--QEEQMGEQEEQ 242
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 49.7 bits (117), Expect = 4e-06
Identities = 31/84 (36%), Positives = 54/84 (64%), Gaps = 5/84 (5%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQER--RKKKEMEERMSLEETKEQILKLEEKLLALQ 80
M E E K QE+EE + E+K++E++E+ R++K +++ + E +E++ + EEK+ Q
Sbjct: 457 MQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWE-Q 515
Query: 81 EEKHQLFLQLKKVLHEEEKRRRKE 104
EEK Q Q +K+ +EEK R +E
Sbjct: 516 EEKMQE--QEEKMQRQEEKMREQE 537
Score = 49.3 bits (116), Expect = 5e-06
Identities = 30/81 (37%), Positives = 52/81 (64%), Gaps = 7/81 (8%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEE 82
M E+E K +E+E DKM Q+ K ++ K +E EE+M +E E+I + +EK+ QE+
Sbjct: 334 MHEQEEKIREQE--DKMWRQEEKIREQEEKIREQEEKMWRQE--EKIREQDEKI---QEQ 386
Query: 83 KHQLFLQLKKVLHEEEKRRRK 103
+ +++ Q +K+ +EEKR+ K
Sbjct: 387 EEEMWRQEEKIREQEEKRQEK 407
Score = 48.5 bits (114), Expect = 8e-06
Identities = 30/94 (31%), Positives = 59/94 (62%), Gaps = 13/94 (13%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQERRKKKE-----MEERMSLEETK----EQILKLEEK 75
E E Q++EE + +E+KM+EE+E+ +++E EE++ +E K E++LK EEK
Sbjct: 438 ELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEK 497
Query: 76 LLALQE----EKHQLFLQLKKVLHEEEKRRRKEQ 105
+ +E ++ +++ Q +K+ +EEK +R+E+
Sbjct: 498 IWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEE 531
Score = 46.6 bits (109), Expect = 3e-05
Identities = 29/86 (33%), Positives = 55/86 (63%), Gaps = 6/86 (6%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQE---RRKKKEMEERMSLEETKEQILKLEEKLLALQE 81
E+E K +EE + E+K++E++E R+++K E+ ++E +E++ + EEK+ QE
Sbjct: 343 EQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKI-REQE 401
Query: 82 EKHQ--LFLQLKKVLHEEEKRRRKEQ 105
EK Q ++ Q KK+ ++EK R +E+
Sbjct: 402 EKRQEKMWRQEKKMREQDEKIREQEE 427
Score = 45.8 bits (107), Expect = 5e-05
Identities = 31/96 (32%), Positives = 55/96 (57%), Gaps = 13/96 (13%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKE-----EQERRKKKEMEERMSLEETK-----EQILKL 72
M E++ K +E+EE E+K++E + + K +E+EE+M EE K E+I +
Sbjct: 415 MREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQ 474
Query: 73 EEKLLALQEE---KHQLFLQLKKVLHEEEKRRRKEQ 105
EEK+ +E+ + +L Q +K+ +EEK R+E+
Sbjct: 475 EEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEE 510
Score = 45.4 bits (106), Expect = 7e-05
Identities = 24/84 (28%), Positives = 53/84 (63%), Gaps = 4/84 (4%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKH 84
E++ K QE+EE E+K++E++E+R++K + + E E+I + EE++ QEEK
Sbjct: 378 EQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWR-QEEK- 435
Query: 85 QLFLQLKKVLHEEEKRRRKEQSDL 108
+L++++ ++E++ R+ + +
Sbjct: 436 --IRELEEMMQDQEEKLREVEEKM 457
Score = 44.7 bits (104), Expect = 1e-04
Identities = 26/83 (31%), Positives = 55/83 (66%), Gaps = 7/83 (8%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEE 82
M +E+K +E++E + E++M ++E K +E+EE M ++ +E++ ++EEK +QEE
Sbjct: 408 MWRQEKKMREQDEKIREQEEEMWRQEE--KIRELEEMM--QDQEEKLREVEEK---MQEE 460
Query: 83 KHQLFLQLKKVLHEEEKRRRKEQ 105
+ ++ Q +K+ +EEK + +E+
Sbjct: 461 EEKMQEQEEKIQRQEEKIQEQEE 483
Score = 44.3 bits (103), Expect = 2e-04
Identities = 29/83 (34%), Positives = 49/83 (59%), Gaps = 7/83 (8%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEE 82
M +E K QE+EE KM EQ++K ++ K EE+M E +E+I + E+K+ +E+
Sbjct: 299 MWRQEEKIQEQEE--KMCEQELKIREQEEKMWRQEEKM--HEQEEKIREQEDKMWRQEEK 354
Query: 83 KHQLFLQLKKVLHEEEKRRRKEQ 105
+ Q +K+ +EEK R+E+
Sbjct: 355 IRE---QEEKIREQEEKMWRQEE 374
Score = 42.4 bits (98), Expect = 6e-04
Identities = 21/75 (28%), Positives = 48/75 (64%)
Query: 31 QEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKHQLFLQL 90
Q++EE E+K++E++E+ ++E++ R E+ Q K+ E+ ++E++ +++ Q
Sbjct: 293 QQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQE 352
Query: 91 KKVLHEEEKRRRKEQ 105
+K+ +EEK R +E+
Sbjct: 353 EKIREQEEKIREQEE 367
Score = 39.3 bits (90), Expect = 0.005
Identities = 21/74 (28%), Positives = 45/74 (60%), Gaps = 3/74 (4%)
Query: 32 EEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKHQLFLQLK 91
EE E+ ++ Q+ +E+ R+++K E+ + E + +I + EEK+ +E+ H+ Q +
Sbjct: 283 EENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHE---QEE 339
Query: 92 KVLHEEEKRRRKEQ 105
K+ +E+K R+E+
Sbjct: 340 KIREQEDKMWRQEE 353
Score = 37.0 bits (84), Expect = 0.024
Identities = 25/80 (31%), Positives = 43/80 (53%), Gaps = 5/80 (6%)
Query: 6 ERPKLSNAMARALHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEET 65
+ K+ + + ++++E K E+EE E+KM E++E K +E EE+M +E
Sbjct: 474 QEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEE--KMQEQEEKMQRQEE 531
Query: 66 KEQILKLEEKLLALQEEKHQ 85
K ++ +E L QEEK Q
Sbjct: 532 K---MREQEVRLWQQEEKMQ 548
Score = 37.0 bits (84), Expect = 0.024
Identities = 30/91 (32%), Positives = 47/91 (51%), Gaps = 11/91 (12%)
Query: 23 MMERERKRQEEEEV-----DKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLL 77
M E+E K QE+EE +KM EQ+++ Q+ K +E E R L+E +E++ KL +K
Sbjct: 512 MWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVR--LQELEERLGKLGQKAE 569
Query: 78 AL----QEEKHQLFLQLKKVLHEEEKRRRKE 104
L +E Q L +L E K + +
Sbjct: 570 LLGGAGRESGSQRLPTLTPILQVELKSQEAQ 600
Score = 36.2 bits (82), Expect = 0.041
Identities = 23/86 (26%), Positives = 54/86 (62%), Gaps = 7/86 (8%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQE---RRKKKEMEERMSLEETKEQILKLEEKLLAL 79
+ E+E K +E++ K E+K+ E++E R+++K E+ ++E +E++ + EEK +
Sbjct: 478 IQEQEEKTWRQEKLLKQ-EEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEK---M 533
Query: 80 QEEKHQLFLQLKKVLHEEEKRRRKEQ 105
+E++ +L+ Q +K+ +E + + E+
Sbjct: 534 REQEVRLWQQEEKMQEQEVRLQELEE 559
Score = 34.7 bits (78), Expect = 0.12
Identities = 19/62 (30%), Positives = 37/62 (59%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKH 84
E+E K +EE E+KM+E++E+ +++E + R +Q K++E+ + LQE +
Sbjct: 500 EQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEE 559
Query: 85 QL 86
+L
Sbjct: 560 RL 561
Score = 30.0 bits (66), Expect = 2.9
Identities = 15/58 (25%), Positives = 34/58 (58%)
Query: 42 QKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKHQLFLQLKKVLHEEEK 99
+K+ +E++ + ++ EE KE+ +L+EKL ++ EK ++ L +K + + E+
Sbjct: 193 EKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLER 250
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 49.7 bits (117), Expect = 4e-06
Identities = 31/84 (36%), Positives = 54/84 (64%), Gaps = 5/84 (5%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQER--RKKKEMEERMSLEETKEQILKLEEKLLALQ 80
M E E K QE+EE + E+K++E++E+ R++K +++ + E +E++ + EEK+ Q
Sbjct: 457 MQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWE-Q 515
Query: 81 EEKHQLFLQLKKVLHEEEKRRRKE 104
EEK Q Q +K+ +EEK R +E
Sbjct: 516 EEKMQE--QEEKMQRQEEKMREQE 537
Score = 49.3 bits (116), Expect = 5e-06
Identities = 30/81 (37%), Positives = 52/81 (64%), Gaps = 7/81 (8%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEE 82
M E+E K +E+E DKM Q+ K ++ K +E EE+M +E E+I + +EK+ QE+
Sbjct: 334 MHEQEEKIREQE--DKMWRQEEKIREQEEKIREQEEKMWRQE--EKIREQDEKI---QEQ 386
Query: 83 KHQLFLQLKKVLHEEEKRRRK 103
+ +++ Q +K+ +EEKR+ K
Sbjct: 387 EEEMWRQEEKIREQEEKRQEK 407
Score = 48.5 bits (114), Expect = 8e-06
Identities = 30/94 (31%), Positives = 59/94 (62%), Gaps = 13/94 (13%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQERRKKKE-----MEERMSLEETK----EQILKLEEK 75
E E Q++EE + +E+KM+EE+E+ +++E EE++ +E K E++LK EEK
Sbjct: 438 ELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEK 497
Query: 76 LLALQE----EKHQLFLQLKKVLHEEEKRRRKEQ 105
+ +E ++ +++ Q +K+ +EEK +R+E+
Sbjct: 498 IWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEE 531
Score = 46.6 bits (109), Expect = 3e-05
Identities = 29/86 (33%), Positives = 55/86 (63%), Gaps = 6/86 (6%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQE---RRKKKEMEERMSLEETKEQILKLEEKLLALQE 81
E+E K +EE + E+K++E++E R+++K E+ ++E +E++ + EEK+ QE
Sbjct: 343 EQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKI-REQE 401
Query: 82 EKHQ--LFLQLKKVLHEEEKRRRKEQ 105
EK Q ++ Q KK+ ++EK R +E+
Sbjct: 402 EKRQEKMWRQEKKMREQDEKIREQEE 427
Score = 45.8 bits (107), Expect = 5e-05
Identities = 31/96 (32%), Positives = 55/96 (57%), Gaps = 13/96 (13%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKE-----EQERRKKKEMEERMSLEETK-----EQILKL 72
M E++ K +E+EE E+K++E + + K +E+EE+M EE K E+I +
Sbjct: 415 MREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQ 474
Query: 73 EEKLLALQEE---KHQLFLQLKKVLHEEEKRRRKEQ 105
EEK+ +E+ + +L Q +K+ +EEK R+E+
Sbjct: 475 EEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEE 510
Score = 45.4 bits (106), Expect = 7e-05
Identities = 24/84 (28%), Positives = 53/84 (63%), Gaps = 4/84 (4%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKH 84
E++ K QE+EE E+K++E++E+R++K + + E E+I + EE++ QEEK
Sbjct: 378 EQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWR-QEEK- 435
Query: 85 QLFLQLKKVLHEEEKRRRKEQSDL 108
+L++++ ++E++ R+ + +
Sbjct: 436 --IRELEEMMQDQEEKLREVEEKM 457
Score = 44.7 bits (104), Expect = 1e-04
Identities = 26/83 (31%), Positives = 55/83 (66%), Gaps = 7/83 (8%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEE 82
M +E+K +E++E + E++M ++E K +E+EE M ++ +E++ ++EEK +QEE
Sbjct: 408 MWRQEKKMREQDEKIREQEEEMWRQEE--KIRELEEMM--QDQEEKLREVEEK---MQEE 460
Query: 83 KHQLFLQLKKVLHEEEKRRRKEQ 105
+ ++ Q +K+ +EEK + +E+
Sbjct: 461 EEKMQEQEEKIQRQEEKIQEQEE 483
Score = 44.3 bits (103), Expect = 2e-04
Identities = 29/83 (34%), Positives = 49/83 (59%), Gaps = 7/83 (8%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEE 82
M +E K QE+EE KM EQ++K ++ K EE+M E +E+I + E+K+ +E+
Sbjct: 299 MWRQEEKIQEQEE--KMCEQELKIREQEEKMWRQEEKM--HEQEEKIREQEDKMWRQEEK 354
Query: 83 KHQLFLQLKKVLHEEEKRRRKEQ 105
+ Q +K+ +EEK R+E+
Sbjct: 355 IRE---QEEKIREQEEKMWRQEE 374
Score = 42.4 bits (98), Expect = 6e-04
Identities = 21/75 (28%), Positives = 48/75 (64%)
Query: 31 QEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKHQLFLQL 90
Q++EE E+K++E++E+ ++E++ R E+ Q K+ E+ ++E++ +++ Q
Sbjct: 293 QQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQE 352
Query: 91 KKVLHEEEKRRRKEQ 105
+K+ +EEK R +E+
Sbjct: 353 EKIREQEEKIREQEE 367
Score = 39.3 bits (90), Expect = 0.005
Identities = 21/74 (28%), Positives = 45/74 (60%), Gaps = 3/74 (4%)
Query: 32 EEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKHQLFLQLK 91
EE E+ ++ Q+ +E+ R+++K E+ + E + +I + EEK+ +E+ H+ Q +
Sbjct: 283 EENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHE---QEE 339
Query: 92 KVLHEEEKRRRKEQ 105
K+ +E+K R+E+
Sbjct: 340 KIREQEDKMWRQEE 353
Score = 37.0 bits (84), Expect = 0.024
Identities = 25/80 (31%), Positives = 43/80 (53%), Gaps = 5/80 (6%)
Query: 6 ERPKLSNAMARALHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEET 65
+ K+ + + ++++E K E+EE E+KM E++E K +E EE+M +E
Sbjct: 474 QEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEE--KMQEQEEKMQRQEE 531
Query: 66 KEQILKLEEKLLALQEEKHQ 85
K ++ +E L QEEK Q
Sbjct: 532 K---MREQEVRLWQQEEKMQ 548
Score = 37.0 bits (84), Expect = 0.024
Identities = 30/91 (32%), Positives = 47/91 (51%), Gaps = 11/91 (12%)
Query: 23 MMERERKRQEEEEV-----DKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLL 77
M E+E K QE+EE +KM EQ+++ Q+ K +E E R L+E +E++ KL +K
Sbjct: 512 MWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVR--LQELEERLGKLGQKAE 569
Query: 78 AL----QEEKHQLFLQLKKVLHEEEKRRRKE 104
L +E Q L +L E K + +
Sbjct: 570 LLGGAGRESGSQRLPTLTPILQVELKSQEAQ 600
Score = 36.2 bits (82), Expect = 0.041
Identities = 23/86 (26%), Positives = 54/86 (62%), Gaps = 7/86 (8%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQE---RRKKKEMEERMSLEETKEQILKLEEKLLAL 79
+ E+E K +E++ K E+K+ E++E R+++K E+ ++E +E++ + EEK +
Sbjct: 478 IQEQEEKTWRQEKLLKQ-EEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEK---M 533
Query: 80 QEEKHQLFLQLKKVLHEEEKRRRKEQ 105
+E++ +L+ Q +K+ +E + + E+
Sbjct: 534 REQEVRLWQQEEKMQEQEVRLQELEE 559
Score = 34.7 bits (78), Expect = 0.12
Identities = 19/62 (30%), Positives = 37/62 (59%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKH 84
E+E K +EE E+KM+E++E+ +++E + R +Q K++E+ + LQE +
Sbjct: 500 EQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEE 559
Query: 85 QL 86
+L
Sbjct: 560 RL 561
Score = 30.0 bits (66), Expect = 2.9
Identities = 15/58 (25%), Positives = 34/58 (58%)
Query: 42 QKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKHQLFLQLKKVLHEEEK 99
+K+ +E++ + ++ EE KE+ +L+EKL ++ EK ++ L +K + + E+
Sbjct: 193 EKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLER 250
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 49.7 bits (117), Expect = 4e-06
Identities = 30/83 (36%), Positives = 52/83 (62%), Gaps = 8/83 (9%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEE 82
+ ERE K QE+EE + E+KM+ ++E +K EE+M +E E + + EEK+ L+E+
Sbjct: 297 IQEREEKIQEQEEKIREQEEKMRRQEEMMWEK--EEKMRRQE--EMMWEKEEKIRELEEK 352
Query: 83 KHQLFLQLKKVLHEEEKRRRKEQ 105
H + +K+ +EEKR+ +E+
Sbjct: 353 MH----EQEKIREQEEKRQEEEK 371
Score = 49.7 bits (117), Expect = 4e-06
Identities = 30/85 (35%), Positives = 55/85 (64%), Gaps = 10/85 (11%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQE----RRKKKEMEERMSLEETKEQILKLEEKLLALQ 80
E+E KRQEEE K+ EQ+ ++EQE R+++K E+ + E +E + + EEK +
Sbjct: 361 EQEEKRQEEE---KIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEK---MG 414
Query: 81 EEKHQLFLQLKKVLHEEEKRRRKEQ 105
E++ +++ Q +++ +EEK RR+E+
Sbjct: 415 EQEEKMWEQEEEMQEQEEKMRRQEE 439
Score = 49.7 bits (117), Expect = 4e-06
Identities = 30/90 (33%), Positives = 58/90 (64%), Gaps = 7/90 (7%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQER-RKKKEM----EERMSLEETK--EQILKLEEK 75
M E+E K + +EE + E+K++E++E+ R+++EM EE+M +E K EQ K++E+
Sbjct: 427 MQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQ 486
Query: 76 LLALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
++ ++ ++ Q KK+ +EEK R +E+
Sbjct: 487 EEKMRRQEEKIREQEKKIREQEEKIREQEE 516
Score = 49.7 bits (117), Expect = 4e-06
Identities = 25/84 (29%), Positives = 53/84 (63%)
Query: 22 IMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQE 81
+M E+E K E+E E KM+E++E+ +++E + R ++ +EQ K+ E+ +QE
Sbjct: 461 MMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQE 520
Query: 82 EKHQLFLQLKKVLHEEEKRRRKEQ 105
++ +++ Q +K+ +EEK + +E+
Sbjct: 521 QEEKMWEQEEKMCEQEEKMQEQEE 544
Score = 48.9 bits (115), Expect = 6e-06
Identities = 26/83 (31%), Positives = 52/83 (62%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEE 82
M E+E K E+EE + E+KM+ ++E+ +++E + R E+ +EQ ++E+ + E+
Sbjct: 413 MGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQ 472
Query: 83 KHQLFLQLKKVLHEEEKRRRKEQ 105
+ ++ Q K+ +EEK RR+E+
Sbjct: 473 EGKMCEQEAKMQEQEEKMRRQEE 495
Score = 48.9 bits (115), Expect = 6e-06
Identities = 30/85 (35%), Positives = 55/85 (64%), Gaps = 6/85 (7%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQERRKKKE---MEERMSLEETKEQILKLEEKLLAL 79
M E+E K QE+EE + E+K++E++++ +++E E+ ++E +E++ + EEK+
Sbjct: 476 MCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCE- 534
Query: 80 QEEKHQLFLQLKKVLHEEEKRRRKE 104
QEEK Q Q +K+ +EEK R +E
Sbjct: 535 QEEKMQ--EQEEKMRRQEEKMREQE 557
Score = 48.5 bits (114), Expect = 8e-06
Identities = 29/90 (32%), Positives = 55/90 (61%), Gaps = 7/90 (7%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQER-----RKKKEMEERMSLEETK--EQILKLEEK 75
M E+E + QE+EE + E+K++E++++ K +E EE M +E K EQ K+ E+
Sbjct: 420 MWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQ 479
Query: 76 LLALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
+QE++ ++ Q +K+ +E+K R +E+
Sbjct: 480 EAKMQEQEEKMRRQEEKIREQEKKIREQEE 509
Score = 47.0 bits (110), Expect = 2e-05
Identities = 24/84 (28%), Positives = 52/84 (61%)
Query: 22 IMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQE 81
+M E+E K E+EE E++M+E++E+ +++E + R ++ +EQ K+ E+ +QE
Sbjct: 405 MMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQE 464
Query: 82 EKHQLFLQLKKVLHEEEKRRRKEQ 105
++ ++ Q K+ +E K + +E+
Sbjct: 465 QEEKMGEQEGKMCEQEAKMQEQEE 488
Score = 46.2 bits (108), Expect = 4e-05
Identities = 29/91 (31%), Positives = 54/91 (59%), Gaps = 7/91 (7%)
Query: 18 LHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLL 77
L + ++E K +EE + E+K++E++E K +E EE+M +E E + + EEK+
Sbjct: 278 LWNRLNQQQEEKMWRQEEKIQEREEKIQEQEE--KIREQEEKMRRQE--EMMWEKEEKMR 333
Query: 78 ALQE---EKHQLFLQLKKVLHEEEKRRRKEQ 105
+E EK + +L++ +HE+EK R +E+
Sbjct: 334 RQEEMMWEKEEKIRELEEKMHEQEKIREQEE 364
Score = 44.7 bits (104), Expect = 1e-04
Identities = 25/83 (30%), Positives = 52/83 (62%), Gaps = 3/83 (3%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEE 82
M E+E+ R++EE K E++ EQE+R+++E + E+ +EQ K+ E+ +QE+
Sbjct: 353 MHEQEKIREQEE---KRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQ 409
Query: 83 KHQLFLQLKKVLHEEEKRRRKEQ 105
+ ++ Q +K+ +EE+ + +E+
Sbjct: 410 EEKMGEQEEKMWEQEEEMQEQEE 432
Score = 44.3 bits (103), Expect = 2e-04
Identities = 26/106 (24%), Positives = 60/106 (56%), Gaps = 6/106 (5%)
Query: 6 ERPKLSNAMARALHRHIMMERERKRQEEEEV----DKMMEQKMKEEQERRKKKEMEERMS 61
E+ K+ + + E+E+++++E ++ +K+ EQ+ K ++ +E EE+M
Sbjct: 355 EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMG 414
Query: 62 LEETK--EQILKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
+E K EQ +++E+ ++ ++ ++ Q KK+ +EEK R +E+
Sbjct: 415 EQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEE 460
Score = 43.5 bits (101), Expect = 3e-04
Identities = 23/84 (27%), Positives = 51/84 (60%), Gaps = 3/84 (3%)
Query: 22 IMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQE 81
+M E+E K + +EE+ E+K++E +E+ ++E + +E+ ++ +EK QE
Sbjct: 324 MMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEK---RQE 380
Query: 82 EKHQLFLQLKKVLHEEEKRRRKEQ 105
++ +++ Q +K+ +EEK R +E+
Sbjct: 381 QEAKMWRQEEKIREQEEKIREQEE 404
Score = 40.0 bits (92), Expect = 0.003
Identities = 25/83 (30%), Positives = 53/83 (63%), Gaps = 7/83 (8%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEE 82
M +E K +E+E+ + E+K++E++E +E EE+M E +E++ + EEK +QE+
Sbjct: 490 MRRQEEKIREQEKKIREQEEKIREQEE--MMQEQEEKM--WEQEEKMCEQEEK---MQEQ 542
Query: 83 KHQLFLQLKKVLHEEEKRRRKEQ 105
+ ++ Q +K+ +E + R++E+
Sbjct: 543 EEKMRRQEEKMREQEVRLRQQEE 565
Score = 39.7 bits (91), Expect = 0.004
Identities = 26/65 (40%), Positives = 40/65 (61%), Gaps = 6/65 (9%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETK----EQILKLEEKLLALQ 80
E+E K +E+EE+ + E+KM E++E K E EE+M +E K E+ ++ +E L Q
Sbjct: 506 EQEEKIREQEEMMQEQEEKMWEQEE--KMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQ 563
Query: 81 EEKHQ 85
EEK Q
Sbjct: 564 EEKMQ 568
Score = 35.8 bits (81), Expect = 0.053
Identities = 19/74 (25%), Positives = 43/74 (58%), Gaps = 3/74 (4%)
Query: 32 EEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKHQLFLQLK 91
EE E+ + Q+ +E+ R+++K E ++E +E+I + EEK+ + ++ ++ + +
Sbjct: 274 EENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKM---RRQEEMMWEKEE 330
Query: 92 KVLHEEEKRRRKEQ 105
K+ +EE KE+
Sbjct: 331 KMRRQEEMMWEKEE 344
Score = 33.9 bits (76), Expect = 0.20
Identities = 15/45 (33%), Positives = 29/45 (64%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKE 67
M E+E K E+EE + E+KM+ ++E+ +++E+ R E+ +E
Sbjct: 525 MWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
Score = 33.1 bits (74), Expect = 0.35
Identities = 18/70 (25%), Positives = 42/70 (60%), Gaps = 1/70 (1%)
Query: 32 EEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKHQLFLQLK 91
++++ D+ +E+ KE ++ + ++ EE KE+ KL+EKL ++ EK ++ L +K
Sbjct: 175 QKKKADRYIEELTKE-RDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVK 233
Query: 92 KVLHEEEKRR 101
++ + E+ +
Sbjct: 234 ELKRKLERAK 243
Score = 31.6 bits (70), Expect = 1.0
Identities = 24/98 (24%), Positives = 49/98 (50%), Gaps = 13/98 (13%)
Query: 9 KLSNAMARALHRHIMMERERKRQEEEEVDKMMEQKMKE-EQERRKKKEMEERMSLEETKE 67
KL A + + E + +E + V ++ +++E E R ++ EE+M +E K
Sbjct: 238 KLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEK- 296
Query: 68 QILKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
++E+ +QE++ +K+ +EEK RR+E+
Sbjct: 297 ----IQEREEKIQEQE-------EKIREQEEKMRRQEE 323
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 49.3 bits (116), Expect = 5e-06
Identities = 28/91 (30%), Positives = 56/91 (61%), Gaps = 6/91 (6%)
Query: 18 LHRHIMMERERKRQEEEEVDKMMEQKMKEEQE---RRKKKEMEERMSLEETKEQILKLEE 74
+H + E KRQE+E+ E+K++E++E R+++K E+ +E +E++ K EE
Sbjct: 553 MHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEE 612
Query: 75 KLLALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
K ++E++ ++ Q +K+ +EEK R +E+
Sbjct: 613 K---IREQEEKIQEQEEKIREQEEKIREQEE 640
Score = 48.9 bits (115), Expect = 6e-06
Identities = 28/90 (31%), Positives = 57/90 (63%), Gaps = 6/90 (6%)
Query: 18 LHRHIMMERERKRQEEEEVDKMMEQKMKEEQE--RRKKKEMEERMSLEETKEQILKLEEK 75
+H + E KRQE+EE+ + E+K+ E++E R+K+K E+ + + +E++ + EEK
Sbjct: 460 IHEQEKIREEEKRQEQEEMWR-QEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEK 518
Query: 76 LLALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
++E++ ++ Q +K+ +EEK R +E+
Sbjct: 519 ---IREQEEKIREQEEKMWRQEEKIREQEE 545
Score = 48.9 bits (115), Expect = 6e-06
Identities = 29/83 (34%), Positives = 52/83 (62%), Gaps = 4/83 (4%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETK--EQILKLEEKLLALQEE 82
E+E K QE+EE + E+K++E++E +E EE+M +E K EQ K++E+ + +
Sbjct: 616 EQEEKIQEQEEKIREQEEKIREQEE--MTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQ 673
Query: 83 KHQLFLQLKKVLHEEEKRRRKEQ 105
+ ++ Q KK+ +EEK R +E+
Sbjct: 674 EEKIREQEKKIREQEEKIREQEE 696
Score = 48.5 bits (114), Expect = 8e-06
Identities = 30/95 (31%), Positives = 55/95 (57%), Gaps = 14/95 (14%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQER-----RKKKEMEERMSLEETK---------EQIL 70
E+E K +E+EE+ + E+KM E++E+ K +E EE M +E K EQ
Sbjct: 630 EQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEE 689
Query: 71 KLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
K+ E+ +QE++ +++ Q +K+ +EEK + +E+
Sbjct: 690 KIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEE 724
Score = 48.1 bits (113), Expect = 1e-05
Identities = 29/83 (34%), Positives = 53/83 (63%), Gaps = 7/83 (8%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEE 82
M E+E K QE+EE E+K++E++ +K +E EE+ + E +E + + EEK + E+
Sbjct: 656 MCEQEEKMQEQEETMWRQEEKIREQE--KKIREQEEK--IREQEEMMQEQEEK---MWEQ 708
Query: 83 KHQLFLQLKKVLHEEEKRRRKEQ 105
+ ++ Q +K+ +EEK RR+E+
Sbjct: 709 EEKMCEQEEKMQEQEEKMRRQEE 731
Score = 47.8 bits (112), Expect = 1e-05
Identities = 26/82 (31%), Positives = 52/82 (63%), Gaps = 7/82 (8%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKH 84
E+E KRQE+EE E+K++E++E+ +++E E+ +EQ K+ E+ QE++
Sbjct: 595 EQEEKRQEQEEKMWKQEEKIREQEEKIQEQE-------EKIREQEEKIREQEEMTQEQEE 647
Query: 85 QLFLQLKKVLHEEEKRRRKEQS 106
++ Q +K+ +EEK + +E++
Sbjct: 648 KMGEQEEKMCEQEEKMQEQEET 669
Score = 47.8 bits (112), Expect = 1e-05
Identities = 27/86 (31%), Positives = 58/86 (67%), Gaps = 6/86 (6%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQER-RKKKEM--EERMSLEETKEQILKLEEKLLAL 79
M ++E K +E+EE + E+K++E++E+ R+++EM E+ + E +E++ + EEK +
Sbjct: 607 MWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEK---M 663
Query: 80 QEEKHQLFLQLKKVLHEEEKRRRKEQ 105
QE++ ++ Q +K+ +E+K R +E+
Sbjct: 664 QEQEETMWRQEEKIREQEKKIREQEE 689
Score = 46.6 bits (109), Expect = 3e-05
Identities = 28/81 (34%), Positives = 52/81 (64%), Gaps = 11/81 (13%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKH 84
E+E KRQEEE K+ EQ+ ++EQE + ++ E+ + E +E+I + E+K+ +E+ H
Sbjct: 408 EQEEKRQEEE---KIREQEKRQEQEAKMWRQEEK---IREQEEKIREQEKKMWRQEEKIH 461
Query: 85 QLFLQLKKVLHEEEKRRRKEQ 105
+ ++ + EEEKR+ +E+
Sbjct: 462 E-----QEKIREEEKRQEQEE 477
Score = 46.2 bits (108), Expect = 4e-05
Identities = 28/84 (33%), Positives = 52/84 (61%), Gaps = 8/84 (9%)
Query: 22 IMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQE 81
+M E+E K + +EE+ E+KM+ ++E +K EE+M +E E + + EEK+ L+E
Sbjct: 343 MMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEK--EEKMRRQE--EMMWEKEEKIRELEE 398
Query: 82 EKHQLFLQLKKVLHEEEKRRRKEQ 105
+ H + +K+ +EEKR+ +E+
Sbjct: 399 KMH----EQEKIREQEEKRQEEEK 418
Score = 45.8 bits (107), Expect = 5e-05
Identities = 29/103 (28%), Positives = 59/103 (57%), Gaps = 20/103 (19%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQERRKKK-----EMEERMSLEE----TKEQILKLE 73
+ E E K QE+EE + E+K++E++E+ +++ E EE+M +E KE+ ++ +
Sbjct: 309 IQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQ 368
Query: 74 EKLLALQE-----------EKHQLFLQLKKVLHEEEKRRRKEQ 105
E+++ +E EK + +L++ +HE+EK R +E+
Sbjct: 369 EEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEE 411
Score = 44.7 bits (104), Expect = 1e-04
Identities = 30/87 (34%), Positives = 54/87 (62%), Gaps = 8/87 (9%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEET----KEQILKLEEKLLA 78
M +E K QE EE + E+K++E++E K +E EE+M +E KE+ ++ +E+++
Sbjct: 302 MWRQEEKIQEWEEKIQEQEEKIREQEE--KIREQEEKMRRQEEMMWEKEEKMRRQEEMMW 359
Query: 79 LQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
+EEK + Q + + +EEK RR+E+
Sbjct: 360 EKEEKMRR--QEEMMWEKEEKMRRQEE 384
Score = 44.7 bits (104), Expect = 1e-04
Identities = 21/81 (25%), Positives = 52/81 (64%), Gaps = 3/81 (3%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKH 84
E+E K +EE + E+ +EE++ +++++ E +E ++++ + EEK ++E++
Sbjct: 528 EQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEK---IREQEE 584
Query: 85 QLFLQLKKVLHEEEKRRRKEQ 105
+++ Q +K+ +EEKR+ +E+
Sbjct: 585 KVWRQEEKIREQEEKRQEQEE 605
Score = 43.5 bits (101), Expect = 3e-04
Identities = 26/100 (26%), Positives = 53/100 (53%), Gaps = 4/100 (4%)
Query: 6 ERPKLSNAMARALHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEET 65
E K+ R M +E K +E+EE + E+KM ++E+ ++E +
Sbjct: 415 EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQE 474
Query: 66 KEQILKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
+E++ + EEK+ E+ +++ Q +K+ +EEK R++E+
Sbjct: 475 QEEMWRQEEKI----HEQEEIWRQKEKMHEQEEKIRKQEE 510
Score = 43.5 bits (101), Expect = 3e-04
Identities = 27/87 (31%), Positives = 59/87 (67%), Gaps = 9/87 (10%)
Query: 25 ERERK--RQEEE--EVDKMMEQKMKEEQER--RKKKEMEERMSLEETKEQILKLEEKLLA 78
E+E+K RQEE+ E +K+ E++ ++EQE R+++++ E+ + KE++ + EEK
Sbjct: 448 EQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEK--- 504
Query: 79 LQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
+++++ +++ Q +K+ +EEK R +E+
Sbjct: 505 IRKQEEKVWRQEEKIREQEEKIREQEE 531
Score = 43.1 bits (100), Expect = 3e-04
Identities = 23/84 (27%), Positives = 51/84 (60%), Gaps = 3/84 (3%)
Query: 22 IMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQE 81
+M E+E K + +EE+ E+K++E +E+ ++E + +E+ ++ +EK QE
Sbjct: 371 MMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEK---RQE 427
Query: 82 EKHQLFLQLKKVLHEEEKRRRKEQ 105
++ +++ Q +K+ +EEK R +E+
Sbjct: 428 QEAKMWRQEEKIREQEEKIREQEK 451
Score = 43.1 bits (100), Expect = 3e-04
Identities = 29/90 (32%), Positives = 57/90 (63%), Gaps = 9/90 (10%)
Query: 22 IMMERERKRQEEEEVDKMMEQKMKEEQERRKKKE--MEERMSLEETKEQILKLEEKLL-- 77
+M E+E K +E EE KM EQ+ EQE ++++E + E+ +E + ++ + EEK+
Sbjct: 385 MMWEKEEKIRELEE--KMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ 442
Query: 78 --ALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
++E++ +++ Q +K+ HE+EK R +E+
Sbjct: 443 EEKIREQEKKMWRQEEKI-HEQEKIREEEK 471
Score = 43.1 bits (100), Expect = 3e-04
Identities = 32/91 (35%), Positives = 55/91 (60%), Gaps = 12/91 (13%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQ---ERRKKKEMEERM-----SLEETKEQILKLEE 74
M +E K +E+EE+ + E+KM E++ E K++E E++M + E +E++ + EE
Sbjct: 533 MWRQEEKIREQEEMWRE-EEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEE 591
Query: 75 KLLALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
K+ QEEK Q Q +K+ +EEK R +E+
Sbjct: 592 KIRE-QEEKRQE--QEEKMWKQEEKIREQEE 619
Score = 40.4 bits (93), Expect = 0.002
Identities = 22/74 (29%), Positives = 46/74 (62%), Gaps = 3/74 (4%)
Query: 32 EEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKHQLFLQLK 91
EE E+ + Q+ +E+ R+++K E ++E +E+I + EEK+ +E++ ++ Q +
Sbjct: 286 EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKI---REQEEKMRRQEE 342
Query: 92 KVLHEEEKRRRKEQ 105
+ +EEK RR+E+
Sbjct: 343 MMWEKEEKMRRQEE 356
Score = 40.0 bits (92), Expect = 0.003
Identities = 25/83 (30%), Positives = 53/83 (63%), Gaps = 7/83 (8%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEE 82
M +E K +E+E+ + E+K++E++E +E EE+M E +E++ + EEK +QE+
Sbjct: 670 MWRQEEKIREQEKKIREQEEKIREQEE--MMQEQEEKM--WEQEEKMCEQEEK---MQEQ 722
Query: 83 KHQLFLQLKKVLHEEEKRRRKEQ 105
+ ++ Q +K+ +E + R++E+
Sbjct: 723 EEKMRRQEEKMWEQEVRLRQQEE 745
Score = 39.3 bits (90), Expect = 0.005
Identities = 28/98 (28%), Positives = 54/98 (55%), Gaps = 6/98 (6%)
Query: 9 KLSNAMARALHRHIMMERERKRQEEEEVDKMMEQKMKE-EQERRKKKEMEERMSLEETKE 67
KL A + + E + +E + V ++ +++E E R ++ EE+M +E E
Sbjct: 250 KLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQE--E 307
Query: 68 QILKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQ 105
+I + EEK+ QE++ ++ Q +K+ +EEK RR+E+
Sbjct: 308 KIQEWEEKI---QEQEEKIREQEEKIREQEEKMRRQEE 342
Score = 39.3 bits (90), Expect = 0.005
Identities = 22/78 (28%), Positives = 47/78 (60%)
Query: 28 RKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKHQLF 87
R Q++EE E+K++E +E+ +++E + R E+ +EQ K+ + + E++ ++
Sbjct: 293 RLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMR 352
Query: 88 LQLKKVLHEEEKRRRKEQ 105
Q + + +EEK RR+E+
Sbjct: 353 RQEEMMWEKEEKMRRQEE 370
Score = 39.3 bits (90), Expect = 0.005
Identities = 23/70 (32%), Positives = 44/70 (62%), Gaps = 9/70 (12%)
Query: 25 ERERKRQEEEEVDKMMEQKMKEEQER---RKKKEMEERMSLEETKEQILKLEEKL----- 76
E+E+K +E+EE + E+ M+E++E+ +++K E+ ++E +E++ + EEK+
Sbjct: 679 EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV 738
Query: 77 -LALQEEKHQ 85
L QEEK Q
Sbjct: 739 RLRQQEEKMQ 748
Score = 33.1 bits (74), Expect = 0.35
Identities = 18/70 (25%), Positives = 42/70 (60%), Gaps = 1/70 (1%)
Query: 32 EEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLALQEEKHQLFLQLK 91
++++ D+ +E+ KE ++ + ++ EE KE+ KL+EKL ++ EK ++ L +K
Sbjct: 187 QKKKADRYIEELTKE-RDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVK 245
Query: 92 KVLHEEEKRR 101
++ + E+ +
Sbjct: 246 ELKRKLERAK 255
Score = 32.0 bits (71), Expect = 0.77
Identities = 15/45 (33%), Positives = 28/45 (62%)
Query: 23 MMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKE 67
M E+E K E+EE + E+KM+ ++E+ ++E+ R E+ +E
Sbjct: 705 MWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
>gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo
sapiens]
Length = 1297
Score = 49.3 bits (116), Expect = 5e-06
Identities = 33/123 (26%), Positives = 65/123 (52%), Gaps = 13/123 (10%)
Query: 20 RHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLA- 78
R ++ ER+++ +E++E + +E++ + E+E RK++E E+R E EQ+ + EE+ A
Sbjct: 385 RQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYE---EQMRREEERRRAE 441
Query: 79 ---------LQEEKHQLFLQLKKVLHEEEKRRRKEQSDLTTLTSAAYQQSLTVHTGTHLL 129
L+EE+ QL + +++LHE+ ++ L A Q +L+
Sbjct: 442 HEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQLEEQRQAERLQRQLKQERDYLV 501
Query: 130 SMQ 132
S+Q
Sbjct: 502 SLQ 504
Score = 42.4 bits (98), Expect = 6e-04
Identities = 25/91 (27%), Positives = 49/91 (53%), Gaps = 5/91 (5%)
Query: 22 IMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLE-----EKL 76
+ ++ K + E + +EQ+ +E +E +++ E + +EE KEQ +LE EK
Sbjct: 355 LRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKE 414
Query: 77 LALQEEKHQLFLQLKKVLHEEEKRRRKEQSD 107
L Q+E+ Q +++ EEE+RR + + +
Sbjct: 415 LRKQQEREQRRHYEEQMRREEERRRAEHEQE 445
Score = 40.8 bits (94), Expect = 0.002
Identities = 30/105 (28%), Positives = 52/105 (49%), Gaps = 14/105 (13%)
Query: 6 ERPKLSNAMARALHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEE--RMSLE 63
+R +L R ERE++R EE+ M+ E+ERR+ + +E R LE
Sbjct: 401 QRRRLEEQQRREKELRKQQEREQRRHYEEQ--------MRREEERRRAEHEQEYIRRQLE 452
Query: 64 ETKEQILKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQSDL 108
E + Q+ L+++LL + L L+ K+ EE+++ + Q L
Sbjct: 453 EEQRQLEILQQQLL----HEQALLLEYKRKQLEEQRQAERLQRQL 493
Score = 37.4 bits (85), Expect = 0.018
Identities = 71/337 (21%), Positives = 124/337 (36%), Gaps = 71/337 (21%)
Query: 19 HRHIMMERERKRQEEEEVDKMMEQKMKEEQERR-----------------KKKEMEERMS 61
H M RE +R+ E + + ++++EEQ + K+K++EE+
Sbjct: 426 HYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQLEEQRQ 485
Query: 62 LEETKEQILKLEEKLLALQEEKHQLFLQLKKVLH--------EEEKRRRKEQSDLTTLTS 113
E + Q+ + + L++LQ ++ + KK L+ E+ KE L + S
Sbjct: 486 AERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEIPHLVAVKS 545
Query: 114 -------------------AAYQQSLTVHTGTHLLSMQGS-PGGHN--RPGTLMAADRA- 150
+ +Q++L V + + Q S P N P + DR+
Sbjct: 546 QGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSS 605
Query: 151 ----KQMFGPQVLTTRHYVGSAAAFAGTPEHGQFQGSPGGAYGTAQPPPHYGPTQPAY-S 205
++ P+V + A A +P +G G G+ P T+P S
Sbjct: 606 WLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILES 665
Query: 206 PSQQLRAPSAFPAVQYLSQPQPQPYAVHGHFQPTQTGFLQPGG-ALSLQKQMEHANQQTG 264
P Q+ + S+ + SQP Q G QPG A S ++ AN +
Sbjct: 666 PLQRTSSGSSSSSSTPSSQPSSQ-------------GGSQPGSQAGSSERTRVRANSK-- 710
Query: 265 FSDSSSLRPMHPQALHPAPGL-LASPQLPVQMQPAGK 300
S+ S + P P + P + P P + K
Sbjct: 711 -SEGSPVLPHEPAKVKPEESRDITRPSRPADLTALAK 746
>gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo
sapiens]
Length = 1305
Score = 49.3 bits (116), Expect = 5e-06
Identities = 33/123 (26%), Positives = 65/123 (52%), Gaps = 13/123 (10%)
Query: 20 RHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLA- 78
R ++ ER+++ +E++E + +E++ + E+E RK++E E+R E EQ+ + EE+ A
Sbjct: 385 RQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYE---EQMRREEERRRAE 441
Query: 79 ---------LQEEKHQLFLQLKKVLHEEEKRRRKEQSDLTTLTSAAYQQSLTVHTGTHLL 129
L+EE+ QL + +++LHE+ ++ L A Q +L+
Sbjct: 442 HEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQLEEQRQAERLQRQLKQERDYLV 501
Query: 130 SMQ 132
S+Q
Sbjct: 502 SLQ 504
Score = 42.4 bits (98), Expect = 6e-04
Identities = 25/91 (27%), Positives = 49/91 (53%), Gaps = 5/91 (5%)
Query: 22 IMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLE-----EKL 76
+ ++ K + E + +EQ+ +E +E +++ E + +EE KEQ +LE EK
Sbjct: 355 LRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKE 414
Query: 77 LALQEEKHQLFLQLKKVLHEEEKRRRKEQSD 107
L Q+E+ Q +++ EEE+RR + + +
Sbjct: 415 LRKQQEREQRRHYEEQMRREEERRRAEHEQE 445
Score = 40.8 bits (94), Expect = 0.002
Identities = 30/105 (28%), Positives = 52/105 (49%), Gaps = 14/105 (13%)
Query: 6 ERPKLSNAMARALHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEE--RMSLE 63
+R +L R ERE++R EE+ M+ E+ERR+ + +E R LE
Sbjct: 401 QRRRLEEQQRREKELRKQQEREQRRHYEEQ--------MRREEERRRAEHEQEYIRRQLE 452
Query: 64 ETKEQILKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQSDL 108
E + Q+ L+++LL + L L+ K+ EE+++ + Q L
Sbjct: 453 EEQRQLEILQQQLL----HEQALLLEYKRKQLEEQRQAERLQRQL 493
Score = 37.0 bits (84), Expect = 0.024
Identities = 68/317 (21%), Positives = 119/317 (37%), Gaps = 70/317 (22%)
Query: 19 HRHIMMERERKRQEEEEVDKMMEQKMKEEQERR-----------------KKKEMEERMS 61
H M RE +R+ E + + ++++EEQ + K+K++EE+
Sbjct: 426 HYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQLEEQRQ 485
Query: 62 LEETKEQILKLEEKLLALQEEKHQLFLQLKKVLH--------EEEKRRRKEQSDLTTLTS 113
E + Q+ + + L++LQ ++ + KK L+ E+ KE L + S
Sbjct: 486 AERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEIPHLVAVKS 545
Query: 114 -------------------AAYQQSLTVHTGTHLLSMQGS-PGGHN--RPGTLMAADRA- 150
+ +Q++L V + + Q S P N P + DR+
Sbjct: 546 QGPALTASQSVHEQPTKGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSS 605
Query: 151 ----KQMFGPQVLTTRHYVGSAAAFAGTPEHGQFQGSPGGAYGTAQPPPHYGPTQPAY-S 205
++ P+V + A A +P +G G G+ P T+P S
Sbjct: 606 WLRQEEDIPPKVPQRTTSISPALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILES 665
Query: 206 PSQQLRAPSAFPAVQYLSQPQPQPYAVHGHFQPTQTGFLQPGG-ALSLQKQMEHANQQTG 264
P Q+ + S+ + SQP Q G QPG A S ++ AN +
Sbjct: 666 PLQRTSSGSSSSSSTPSSQPSSQ-------------GGSQPGSQAGSSERTRVRANSK-- 710
Query: 265 FSDSSSLRPMHPQALHP 281
S+ S + P P + P
Sbjct: 711 -SEGSPVLPHEPAKVKP 726
>gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo
sapiens]
Length = 1352
Score = 49.3 bits (116), Expect = 5e-06
Identities = 33/123 (26%), Positives = 65/123 (52%), Gaps = 13/123 (10%)
Query: 20 RHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLEEKLLA- 78
R ++ ER+++ +E++E + +E++ + E+E RK++E E+R E EQ+ + EE+ A
Sbjct: 385 RQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYE---EQMRREEERRRAE 441
Query: 79 ---------LQEEKHQLFLQLKKVLHEEEKRRRKEQSDLTTLTSAAYQQSLTVHTGTHLL 129
L+EE+ QL + +++LHE+ ++ L A Q +L+
Sbjct: 442 HEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQLEEQRQAERLQRQLKQERDYLV 501
Query: 130 SMQ 132
S+Q
Sbjct: 502 SLQ 504
Score = 42.4 bits (98), Expect = 6e-04
Identities = 25/91 (27%), Positives = 49/91 (53%), Gaps = 5/91 (5%)
Query: 22 IMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEERMSLEETKEQILKLE-----EKL 76
+ ++ K + E + +EQ+ +E +E +++ E + +EE KEQ +LE EK
Sbjct: 355 LRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKE 414
Query: 77 LALQEEKHQLFLQLKKVLHEEEKRRRKEQSD 107
L Q+E+ Q +++ EEE+RR + + +
Sbjct: 415 LRKQQEREQRRHYEEQMRREEERRRAEHEQE 445
Score = 40.8 bits (94), Expect = 0.002
Identities = 30/105 (28%), Positives = 52/105 (49%), Gaps = 14/105 (13%)
Query: 6 ERPKLSNAMARALHRHIMMERERKRQEEEEVDKMMEQKMKEEQERRKKKEMEE--RMSLE 63
+R +L R ERE++R EE+ M+ E+ERR+ + +E R LE
Sbjct: 401 QRRRLEEQQRREKELRKQQEREQRRHYEEQ--------MRREEERRRAEHEQEYIRRQLE 452
Query: 64 ETKEQILKLEEKLLALQEEKHQLFLQLKKVLHEEEKRRRKEQSDL 108
E + Q+ L+++LL + L L+ K+ EE+++ + Q L
Sbjct: 453 EEQRQLEILQQQLL----HEQALLLEYKRKQLEEQRQAERLQRQL 493
Score = 33.5 bits (75), Expect = 0.26
Identities = 22/98 (22%), Positives = 47/98 (47%), Gaps = 18/98 (18%)
Query: 19 HRHIMMERERKRQEEEEVDKMMEQKMKEEQERR-----------------KKKEMEERMS 61
H M RE +R+ E + + ++++EEQ + K+K++EE+
Sbjct: 426 HYEEQMRREEERRRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQLEEQRQ 485
Query: 62 LEETKEQILKLEEKLLALQEEK-HQLFLQLKKVLHEEE 98
E + Q+ + + L++LQ ++ Q ++ K + H +E
Sbjct: 486 AERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKE 523
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.128 0.369
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,804,464
Number of Sequences: 37866
Number of extensions: 975191
Number of successful extensions: 23913
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 715
Number of HSP's successfully gapped in prelim test: 1107
Number of HSP's that attempted gapping in prelim test: 8549
Number of HSP's gapped (non-prelim): 9745
length of query: 327
length of database: 18,247,518
effective HSP length: 103
effective length of query: 224
effective length of database: 14,347,320
effective search space: 3213799680
effective search space used: 3213799680
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.