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Search of human proteins with 4758024
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4758024 coilin [Homo sapiens]
(576 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4758024 coilin [Homo sapiens] 1149 0.0
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 54 3e-07
gi|133922600 splicing factor, arginine/serine-rich 16 [Homo sapi... 54 5e-07
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 50 7e-06
gi|95147342 chromodomain helicase DNA binding protein 9 [Homo sa... 50 7e-06
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 47 4e-05
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 47 4e-05
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 46 1e-04
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 46 1e-04
gi|239750213 PREDICTED: hypothetical protein [Homo sapiens] 45 1e-04
gi|169167062 PREDICTED: hypothetical protein LOC285556 [Homo sap... 45 2e-04
gi|113416182 PREDICTED: hypothetical protein LOC285556 [Homo sap... 45 2e-04
gi|113415686 PREDICTED: hypothetical protein LOC285556 [Homo sap... 45 2e-04
gi|87299628 biorientation of chromosomes in cell division 1-like... 45 2e-04
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 45 2e-04
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 45 2e-04
gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithora... 44 3e-04
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 44 3e-04
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] 44 3e-04
gi|41055989 M-phase phosphoprotein 8 [Homo sapiens] 44 4e-04
gi|27262628 nuclear autoantigenic sperm protein isoform 2 [Homo ... 44 4e-04
gi|27262634 nuclear autoantigenic sperm protein isoform 1 [Homo ... 44 4e-04
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 44 5e-04
gi|168229156 NFKB activating protein [Homo sapiens] 44 5e-04
gi|239744133 PREDICTED: hypothetical protein [Homo sapiens] 44 5e-04
gi|156104891 general transcription factor IIF, polypeptide 1, 74... 44 5e-04
gi|7661950 SH2 domain binding protein 1 [Homo sapiens] 44 5e-04
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 44 5e-04
gi|239755326 PREDICTED: hypothetical protein [Homo sapiens] 43 7e-04
gi|13376245 zinc finger protein 403 [Homo sapiens] 43 7e-04
>gi|4758024 coilin [Homo sapiens]
Length = 576
Score = 1149 bits (2971), Expect = 0.0
Identities = 576/576 (100%), Positives = 576/576 (100%)
Query: 1 MAASETVRLRLQFDYPPPATPHCTAFWLLVDLNRCRVVTDLISLIRQRFGFSSGAFLGLY 60
MAASETVRLRLQFDYPPPATPHCTAFWLLVDLNRCRVVTDLISLIRQRFGFSSGAFLGLY
Sbjct: 1 MAASETVRLRLQFDYPPPATPHCTAFWLLVDLNRCRVVTDLISLIRQRFGFSSGAFLGLY 60
Query: 61 LEGGLLPPAESARLVRDNDCLRVKLEERGVAENSVVISNGDINLSLRKAKKRAFQLEEGE 120
LEGGLLPPAESARLVRDNDCLRVKLEERGVAENSVVISNGDINLSLRKAKKRAFQLEEGE
Sbjct: 61 LEGGLLPPAESARLVRDNDCLRVKLEERGVAENSVVISNGDINLSLRKAKKRAFQLEEGE 120
Query: 121 ETEPDCKYSKKHWKSRENNNNNEKVLDLEPKAVTDQTVSKKNKRKNKATCGTVGDDNEEA 180
ETEPDCKYSKKHWKSRENNNNNEKVLDLEPKAVTDQTVSKKNKRKNKATCGTVGDDNEEA
Sbjct: 121 ETEPDCKYSKKHWKSRENNNNNEKVLDLEPKAVTDQTVSKKNKRKNKATCGTVGDDNEEA 180
Query: 181 KRKSPKKKEKCEYKKKAKNPKSPKVQAVKDWANQRCSSPKGSARNSLVKAKRKGSVSVCS 240
KRKSPKKKEKCEYKKKAKNPKSPKVQAVKDWANQRCSSPKGSARNSLVKAKRKGSVSVCS
Sbjct: 181 KRKSPKKKEKCEYKKKAKNPKSPKVQAVKDWANQRCSSPKGSARNSLVKAKRKGSVSVCS 240
Query: 241 KESPSSSSESESCDESISDGPSKVTLEARNSSEKLPTELSKEEPSTKNTTADKLAIKLGF 300
KESPSSSSESESCDESISDGPSKVTLEARNSSEKLPTELSKEEPSTKNTTADKLAIKLGF
Sbjct: 241 KESPSSSSESESCDESISDGPSKVTLEARNSSEKLPTELSKEEPSTKNTTADKLAIKLGF 300
Query: 301 SLTPSKGKTSGTTSSSSDSSAESDDQCLMSSSTPECAAGFLKTVGLFAGRGRPGPGLSSQ 360
SLTPSKGKTSGTTSSSSDSSAESDDQCLMSSSTPECAAGFLKTVGLFAGRGRPGPGLSSQ
Sbjct: 301 SLTPSKGKTSGTTSSSSDSSAESDDQCLMSSSTPECAAGFLKTVGLFAGRGRPGPGLSSQ 360
Query: 361 TAGAAGWRRSGSNGGGQAPGASPSVSLPASLGRGWGREENLFSWKGAKGRGMRGRGRGRG 420
TAGAAGWRRSGSNGGGQAPGASPSVSLPASLGRGWGREENLFSWKGAKGRGMRGRGRGRG
Sbjct: 361 TAGAAGWRRSGSNGGGQAPGASPSVSLPASLGRGWGREENLFSWKGAKGRGMRGRGRGRG 420
Query: 421 HPVSCVVNRSTDNQRQQQLNDVVKNSSTIIQNPVETPKKDYSLLPLLAAAPQVGEKIAFK 480
HPVSCVVNRSTDNQRQQQLNDVVKNSSTIIQNPVETPKKDYSLLPLLAAAPQVGEKIAFK
Sbjct: 421 HPVSCVVNRSTDNQRQQQLNDVVKNSSTIIQNPVETPKKDYSLLPLLAAAPQVGEKIAFK 480
Query: 481 LLELTSSYSPDVSDYKEGRILSHNPETQQVDIEILSSLPALREPGKFDLVYHNENGAEVV 540
LLELTSSYSPDVSDYKEGRILSHNPETQQVDIEILSSLPALREPGKFDLVYHNENGAEVV
Sbjct: 481 LLELTSSYSPDVSDYKEGRILSHNPETQQVDIEILSSLPALREPGKFDLVYHNENGAEVV 540
Query: 541 EYAVTQESKITVFWKELIDPRLIIESPSNTSSTEPA 576
EYAVTQESKITVFWKELIDPRLIIESPSNTSSTEPA
Sbjct: 541 EYAVTQESKITVFWKELIDPRLIIESPSNTSSTEPA 576
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 54.3 bits (129), Expect = 3e-07
Identities = 60/245 (24%), Positives = 98/245 (40%), Gaps = 36/245 (14%)
Query: 111 KRAFQLEEGEETEPDCKYSKKHWKSRENNNNNEKVLDLEPKAVTDQTVSKKNKRKNKATC 170
K+A + ++ E+ D S E+++++E+ KAV + +K K A
Sbjct: 310 KKAVEKQQPVESSED--------SSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAES 361
Query: 171 GTVGDDNEEAKRKSPKKKEKCEYKKKAKNPK-SPKVQAVKDWANQRCSSPKGSARNSLVK 229
+ D++ ++ K K + P + K AVK A + P G + L
Sbjct: 362 SSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPK--QPVGGGQKLLT- 418
Query: 230 AKRKGSVSVCSKESPSSSSESESCDESISDGPSKVTLEAR--------------NSSEKL 275
RK S S E SSSSE E + ++ K T +A +SS+
Sbjct: 419 --RKADSS--SSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSD 474
Query: 276 PTELSKEEPSTKNTTADKLAIKLGFSLTPSK------GKTSGTTSSSSDSSAESDDQCLM 329
+ +EE T + K K+ PSK GK + SSSSD S+E +++ L
Sbjct: 475 SSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLK 534
Query: 330 SSSTP 334
+P
Sbjct: 535 GKGSP 539
Score = 43.5 bits (101), Expect = 5e-04
Identities = 45/194 (23%), Positives = 78/194 (40%), Gaps = 25/194 (12%)
Query: 149 EPKAVTDQTVSKKNKRKNKATCGTVGDDNEEAKRKSPKKKEKCEYKKKAKNPKSPKVQAV 208
E K + V+KK K+K ++ + EE + P KK K+ P +A
Sbjct: 65 ERKLQANGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKAS 124
Query: 209 KDWANQRCSSP------KGSARNSLVKAKRKGSVSVCSK-ESPSSSSESESCDESISDGP 261
+ +++ S K VK + K + + K +S S S+S S DE +
Sbjct: 125 ESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQK 184
Query: 262 SKVTLEARNSSEKLPTELSKEEPSTKNTTADKLAIKLGFSLTPSKGKTSGTTSSSSDSSA 321
K+T + K P + ++ P N GK + ++SSSS SS+
Sbjct: 185 PKITPVTVKAQTKAPPKPARAAPKIAN------------------GKAASSSSSSSSSSS 226
Query: 322 ESDDQCLMSSSTPE 335
D + +++TP+
Sbjct: 227 SDDSEEEKAAATPK 240
Score = 37.7 bits (86), Expect = 0.029
Identities = 47/214 (21%), Positives = 85/214 (39%), Gaps = 22/214 (10%)
Query: 124 PDCKYSKKHWKSRENNNNNEKVLDLEPKAVTDQTVSKKN------KRKNKATCGTVG--- 174
P K +KK S ++ +++E+ +++ V K K KA+ +
Sbjct: 73 PVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEES 132
Query: 175 --DDNEEAKRKSPKKKEKCEYKKKAKNPKSPKVQAVKDWANQRCSSPKGSARNSLVKAKR 232
DD+EE ++K P +K K +AK K+P +A ++ SS +N K
Sbjct: 133 SDDDDEEDQKKQPVQK---GVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKI-- 187
Query: 233 KGSVSVCSKESPSSSSESESCDESISDGPSKVTLEARNSSEKLPTELSKEEPSTKNTTAD 292
V K + + I++G + + + +SS ++ +T T
Sbjct: 188 ---TPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVP 244
Query: 293 KLAIKLGFSLTPSKGKTSGTTSSSSDSSAESDDQ 326
K K + P K T+ T SSS + SD++
Sbjct: 245 K---KQVVAKAPVKAATTPTRKSSSSEDSSSDEE 275
Score = 32.7 bits (73), Expect = 0.93
Identities = 52/245 (21%), Positives = 92/245 (37%), Gaps = 42/245 (17%)
Query: 117 EEGEETEPDCKYSKKHWKSRENNNNNEKVLDLEPKAVTDQTVSKKNKRKNKATCGTVGDD 176
EE ++ +P K K K+ + K D + + ++ K +K K T TV
Sbjct: 138 EEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKN--QKPKITPVTV--- 192
Query: 177 NEEAKRKSPKKKEKCEYK----KKAKNPKSPKVQAVKDWANQR--CSSPKGSARNSLVKA 230
+A+ K+P K + K K A + S + D + + ++PK + V A
Sbjct: 193 --KAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVA 250
Query: 231 KRKGSVSVCSKESPSSSSESESCDESISDGPSK---------------------VTLEAR 269
K + SSS +S S +E P K T +
Sbjct: 251 KAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPK 310
Query: 270 NSSEK-LPTELSKEEPSTKNTTAD-------KLAIKLGFSLTPSKGKTSGTTSSSSDSSA 321
+ EK P E S++ +++++ K + + P K + ++S SSDS +
Sbjct: 311 KAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDS 370
Query: 322 ESDDQ 326
DD+
Sbjct: 371 SEDDE 375
>gi|133922600 splicing factor, arginine/serine-rich 16 [Homo
sapiens]
Length = 674
Score = 53.5 bits (127), Expect = 5e-07
Identities = 96/443 (21%), Positives = 161/443 (36%), Gaps = 55/443 (12%)
Query: 61 LEGGLLPPAESARLVRDNDCLRVKLEERGVAENSVVISNGDINLSLRKAKKRAFQLEEGE 120
L GGL P+E E++ +AE I + ++ + +K A + EE E
Sbjct: 141 LYGGLQRPSED--------------EKKKLAEKKASIGYTYEDSTVAEVEKAAEKPEEEE 186
Query: 121 ETEPDCKYSKKHWKSRENNNNNEKVLDLEPKAVTDQTVSKKNKRKNKATCGTVGDDNEEA 180
+ N++ +E + D++ + D+ ++ NK T G + +
Sbjct: 187 SAAEE----------ESNSDEDEVIPDIDVEVDVDELNQEQVADLNKQAT-TYGMADGDF 235
Query: 181 KRKSPKKKEKCEYKKKAKNPKSPKVQAVKDWANQRCSSPKGSARNSLVKAKRKGSVSVCS 240
R K KE+ E K AK + K ++ +R + R ++ ++ S
Sbjct: 236 VRMLRKDKEEAEAIKHAKALEEEKAM----YSGRRSRRQRREFREKRLRGRKISPPSYAR 291
Query: 241 KESPSSSSESESCDESISDGPSKVTLEARNSSEKLPTELS----KEEPSTKNTTADKLAI 296
++SP+ S ES S+ S+ EK+ S EE + A +
Sbjct: 292 RDSPTYDPYKRSPSESSSESRSRSRSPTPGREEKITFITSFGGSDEEAAAAAAAAAASGV 351
Query: 297 KLGFSLTP-------------SKGKTSGTTSSSSDSSAESDDQCLMSSSTPECAAGFLKT 343
G P ++ ++S ++SSSS S S SSS G+ ++
Sbjct: 352 TTGKPPAPPQPGGPAPGRNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRS 411
Query: 344 VGLFAGRGRPGPGLSSQTAGAAGWRRSG--SNGGGQAPGASPSVSLPASLGRGWGREENL 401
R R S++ + R G +GGG G S S G G R
Sbjct: 412 GRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRS 471
Query: 402 FSWKGAK----GRGMRGRGRGRGH---PVSCVVNRSTDNQRQQQLNDVVKNSSTIIQNPV 454
S G + GRG+R R +S +RS R + S + ++
Sbjct: 472 RSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQS 531
Query: 455 ETPKKDYSLLPLLAAAPQVGEKI 477
+P L AA+P VGEK+
Sbjct: 532 PSPSPAREKLTRPAASPAVGEKL 554
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 49.7 bits (117), Expect = 7e-06
Identities = 51/191 (26%), Positives = 76/191 (39%), Gaps = 14/191 (7%)
Query: 199 NPKSP-KVQAVKDWANQRCSSPKGSARNSLVKAKRKGSVSVCSKESPSSSSESESCDESI 257
NPKSP K QA +D A + SS S+ +S S S SS SE+E +E
Sbjct: 2540 NPKSPDKAQAEQDGAEESESSSSSSSGSSS-----------SSSSSSSSGSETEGEEEGD 2588
Query: 258 SDGPSKVTLEARNSSEKLPTELSKEEPSTKNTTADKLAIKLGFSLTPSKGKTSGTTSSSS 317
+G RN S S S+ ++++ + S + S +S ++SSSS
Sbjct: 2589 KNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2648
Query: 318 DSSAESDDQCLMSSSTPECAAGFLKTVGLFAGRGRPGPGLSSQTAGAAGWRRSGSNGGGQ 377
SS+ S SSS+ ++ T + + TAG + + Q
Sbjct: 2649 SSSSSSSSSSSSSSSSSSSSSS--STTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQ 2706
Query: 378 APGASPSVSLP 388
A A PS P
Sbjct: 2707 AGKARPSAHSP 2717
Score = 30.4 bits (67), Expect = 4.6
Identities = 29/127 (22%), Positives = 44/127 (34%)
Query: 107 RKAKKRAFQLEEGEETEPDCKYSKKHWKSRENNNNNEKVLDLEPKAVTDQTVSKKNKRKN 166
RKA+K E G E P+ + R P V+ +K ++
Sbjct: 1969 RKARKLRGPKEPGFEAGPEASDDDLWTRRRSERIFLHDASAAAPAPVSTAPATKTSRCAK 2028
Query: 167 KATCGTVGDDNEEAKRKSPKKKEKCEYKKKAKNPKSPKVQAVKDWANQRCSSPKGSARNS 226
D RK P+KK+K + P+ A+ A +S +A+ S
Sbjct: 2029 GGPLSPRKDAGRAKDRKDPRKKKKGKEAGPGAGLPPPRAPALPSEARAPHASSLTAAKRS 2088
Query: 227 LVKAKRK 233
KAK K
Sbjct: 2089 KAKAKGK 2095
>gi|95147342 chromodomain helicase DNA binding protein 9 [Homo
sapiens]
Length = 2881
Score = 49.7 bits (117), Expect = 7e-06
Identities = 51/216 (23%), Positives = 81/216 (37%), Gaps = 18/216 (8%)
Query: 125 DCKYSKKHWKSRENNNNNEKVLDLEPKA-VTDQTVSKKNKRKNKATCGTVGDDNEEAKRK 183
+ K ++ K ++ E + +E + + + VS KN +AT GD K +
Sbjct: 2044 EMKVKSENLKEEPQSSEEESMSSVETRTLIKSEPVSPKNGVLPQAT----GDQKSGGKCE 2099
Query: 184 SPKKKEKCEYKKKAKNPKSPKVQAVKDWANQRCSSPKGSARNSLVKAKRKGSVSVCSKES 243
+ ++ + NP S K + K + S S R+S S S S
Sbjct: 2100 TDRRMVAARTEPLTPNPASKKPRVHKRGSESSSDSDSDSERSSCSSRSSSSSSSSSCSHS 2159
Query: 244 PSSS--SESESCDESISDGPSKVTLEARNSSEKLPTELSKEEPSTKNTTADKLAIKLGFS 301
S S S S SC + S S + + +SS S EE + K S
Sbjct: 2160 RSGSSSSSSSSCSSASSSSSSSTSSSSSSSSSSSEESDSDEEEAQKRE-----------S 2208
Query: 302 LTPSKGKTSGTTSSSSDSSAESDDQCLMSSSTPECA 337
T K + +S S + E+ D M++ TPE A
Sbjct: 2209 TTHMKAYDEESVASLSTTQDETQDSFQMNNGTPESA 2244
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 47.4 bits (111), Expect = 4e-05
Identities = 49/200 (24%), Positives = 79/200 (39%), Gaps = 18/200 (9%)
Query: 110 KKRAFQLEEGE----ETEPDCKYSKKHWKSRENNNNNEKVLDLEPKAVTDQTVSKKNKRK 165
K+ + + EEGE ETE + + + K + + + + + V D V K K K
Sbjct: 555 KEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAK 614
Query: 166 NKATCGTVGDDNEEAKRKSPKKKEKCEYKKKAKNPKSPKVQAVKDWANQRCSSPKGSA-- 223
+ V E K KSP K E K K+ PKSP + K + KG +
Sbjct: 615 SPVPKSPV-----EEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPV 669
Query: 224 RNSLVKAKRKGSVSVCSKESPSSSSE------SESCDESISDGPSKVTLEARNSSEK-LP 276
S V+ K K V E S +E E ++ + + P + +E + K +P
Sbjct: 670 SKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVP 729
Query: 277 TELSKEEPSTKNTTADKLAI 296
+ E P + A+ + I
Sbjct: 730 EKKKAESPVKEEAVAEVVTI 749
Score = 35.8 bits (81), Expect = 0.11
Identities = 34/163 (20%), Positives = 77/163 (47%), Gaps = 8/163 (4%)
Query: 149 EPKAVTDQTVSKKNKRKNKATCGTVGDDNEEAKRKSPKKKEKCEYKKKAKNPKSPKVQAV 208
EP+A ++ +KK+ K AT V ++ E + + +++E+ E + AK+ ++ + +
Sbjct: 498 EPEAEEEEVAAKKSPVK--ATAPEVKEEEGEKEEEEGQEEEE-EEDEGAKSDQAEEGGSE 554
Query: 209 KDWANQRCSSPKGSARNSLVKAKRKGSVSVCSKESP--SSSSESESCDESISDGPSKVTL 266
K+ ++++ +G +A+ +G + +E S E + +E ++D +
Sbjct: 555 KEGSSEK---EEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPE 611
Query: 267 EARNSSEKLPTELSKEEPSTKNTTADKLAIKLGFSLTPSKGKT 309
+A++ K P E + P K+ +K + S KGK+
Sbjct: 612 KAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKS 654
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 47.4 bits (111), Expect = 4e-05
Identities = 49/200 (24%), Positives = 79/200 (39%), Gaps = 18/200 (9%)
Query: 110 KKRAFQLEEGE----ETEPDCKYSKKHWKSRENNNNNEKVLDLEPKAVTDQTVSKKNKRK 165
K+ + + EEGE ETE + + + K + + + + + V D V K K K
Sbjct: 179 KEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAK 238
Query: 166 NKATCGTVGDDNEEAKRKSPKKKEKCEYKKKAKNPKSPKVQAVKDWANQRCSSPKGSA-- 223
+ V E K KSP K E K K+ PKSP + K + KG +
Sbjct: 239 SPVPKSPV-----EEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPV 293
Query: 224 RNSLVKAKRKGSVSVCSKESPSSSSE------SESCDESISDGPSKVTLEARNSSEK-LP 276
S V+ K K V E S +E E ++ + + P + +E + K +P
Sbjct: 294 SKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVP 353
Query: 277 TELSKEEPSTKNTTADKLAI 296
+ E P + A+ + I
Sbjct: 354 EKKKAESPVKEEAVAEVVTI 373
Score = 35.8 bits (81), Expect = 0.11
Identities = 34/163 (20%), Positives = 77/163 (47%), Gaps = 8/163 (4%)
Query: 149 EPKAVTDQTVSKKNKRKNKATCGTVGDDNEEAKRKSPKKKEKCEYKKKAKNPKSPKVQAV 208
EP+A ++ +KK+ K AT V ++ E + + +++E+ E + AK+ ++ + +
Sbjct: 122 EPEAEEEEVAAKKSPVK--ATAPEVKEEEGEKEEEEGQEEEE-EEDEGAKSDQAEEGGSE 178
Query: 209 KDWANQRCSSPKGSARNSLVKAKRKGSVSVCSKESP--SSSSESESCDESISDGPSKVTL 266
K+ ++++ +G +A+ +G + +E S E + +E ++D +
Sbjct: 179 KEGSSEK---EEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPE 235
Query: 267 EARNSSEKLPTELSKEEPSTKNTTADKLAIKLGFSLTPSKGKT 309
+A++ K P E + P K+ +K + S KGK+
Sbjct: 236 KAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKS 278
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 45.8 bits (107), Expect = 1e-04
Identities = 33/127 (25%), Positives = 58/127 (45%), Gaps = 12/127 (9%)
Query: 107 RKAKKRAFQLEEGEETEPDCKYSKKHWKSRENNNNNEKVLDLEPKAVTDQTVSKKNKRKN 166
+K KK+ + EE EETE + +K K +E K + E K T +T +K K
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRK--EKEKKKKTKETEKRKEKE-- 56
Query: 167 KATCGTVGDDNEEAKRKSPKKKEKCEYKKKAKNPKSPKVQAVKDWANQRCSSPKGSARNS 226
++ ++ KRK KKKE+ E +++ + + K + K+ +R K +
Sbjct: 57 --------EEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEE 108
Query: 227 LVKAKRK 233
+ K+K
Sbjct: 109 EEEKKKK 115
Score = 37.4 bits (85), Expect = 0.038
Identities = 33/129 (25%), Positives = 52/129 (40%), Gaps = 9/129 (6%)
Query: 160 KKNKRKNKATCGTVG-DDNEEAKRKSPKKKEKCEYKKKAKNPKSPKVQAVKDWANQRCSS 218
KK K+K K T T ++ EE + K K+KEK +K K + K + K+ ++
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEK----RKEKRKEKEKKKKTKETEKRKEKE 56
Query: 219 PKGSARNSLVKAKRKGSVSVCSKESPSSSSESESCDESISDGPSKVTLEARNSSEKLPTE 278
+ R K KRK +E E E +E +G + + R E+ +
Sbjct: 57 EEEKKR----KRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEK 112
Query: 279 LSKEEPSTK 287
K TK
Sbjct: 113 KKKRRRKTK 121
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 45.8 bits (107), Expect = 1e-04
Identities = 46/216 (21%), Positives = 81/216 (37%), Gaps = 16/216 (7%)
Query: 117 EEGEETEPDCKYSKKHWKSRENNNNNEKVLDLEPKAVTDQTVSKKNKRKNKATCGTVGDD 176
+ + D Y+ K N ++++ D + + +D S N N DD
Sbjct: 482 DNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGN-----DD 536
Query: 177 NEEAKRKSPKKKEKCEYKKKAKNPKSPKVQAVKDWANQRCSSPKGSARNSLVKAKRKGSV 236
N+++ K + N + D ++ SS S+ + S
Sbjct: 537 NDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSD--------SS 588
Query: 237 SVCSKESPSSSSESESCDESISDGPSKVTLEARNSSEKLPTELSKEEPSTKNTTADKLAI 296
+S SS+ S+S D S S S + + + S+ +E + +K+ ++D +
Sbjct: 589 DSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSS 648
Query: 297 KLGFSLTPSKGKTSGTTSSSSDSSAESDDQCLMSSS 332
S S S +S+SSDSS SD SSS
Sbjct: 649 D---SSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSS 681
Score = 42.0 bits (97), Expect = 0.002
Identities = 47/261 (18%), Positives = 104/261 (39%), Gaps = 19/261 (7%)
Query: 86 EERGVAENSVVISNGDINLSLRKAKKRAFQLE-EGEETEPDCKYSKKHWKSRENNNNNEK 144
E++G ++ +++ G++ K + +E G+++EP K + S N++ +
Sbjct: 400 EDKG--QHGMILGKGNV-----KTQGEVVNIEGPGQKSEPGNKVGHSNTGSDSNSDGYDS 452
Query: 145 VLDLEPKAVTDQTVSKKNKRKNKATCGTVGDDNEEAKRKSPKKKEKCEYKKKAKNPKSPK 204
D + K++ + ++ + D+N ++ + ++ + + K +
Sbjct: 453 Y-DFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAE 511
Query: 205 VQAVKDWANQRCSSPKGSARNSLVKAKR----KGSVSVCSKESPSSSSESESCDESISDG 260
++ S G+ N + KG +S SS+ S+S D S SD
Sbjct: 512 DDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDS 571
Query: 261 PSKVTLEARNSSEKLPTELSKEEPSTKNTTADKLAIKLGFSLTPS------KGKTSGTTS 314
+ +SS+ ++ S + S + ++D + S K +S + S
Sbjct: 572 SDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSES 631
Query: 315 SSSDSSAESDDQCLMSSSTPE 335
SSDS ++SD SS + +
Sbjct: 632 DSSDSDSKSDSSDSNSSDSSD 652
Score = 36.2 bits (82), Expect = 0.084
Identities = 39/204 (19%), Positives = 83/204 (40%), Gaps = 10/204 (4%)
Query: 125 DCKYSKKHWKSRENNNNNEKVLDLEPKAVTDQTVSKKNKRKNKATCGTVGDDNEEAKRKS 184
D S + S +++N+++ + +D + S + + ++ + D+ ++ S
Sbjct: 1077 DSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1136
Query: 185 PKKK--EKCEYKKKAKNPKSPKVQAVKDWANQRCSSPKGSARNSLVKAKRKGSVSVCSKE 242
+ + + + + S D ++ SS + NS S S S +
Sbjct: 1137 DSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNS--------SDSSDSSD 1188
Query: 243 SPSSSSESESCDESISDGPSKVTLEARNSSEKLPTELSKEEPSTKNTTADKLAIKLGFSL 302
S SS S+S D S S S + + +S ++ S S +++ + + S
Sbjct: 1189 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSN 1248
Query: 303 TPSKGKTSGTTSSSSDSSAESDDQ 326
+ +S ++ S+SDS+ ESD Q
Sbjct: 1249 SSDSSDSSDSSDSTSDSNDESDSQ 1272
>gi|239750213 PREDICTED: hypothetical protein [Homo sapiens]
Length = 248
Score = 45.4 bits (106), Expect = 1e-04
Identities = 45/177 (25%), Positives = 74/177 (41%), Gaps = 9/177 (5%)
Query: 87 ERGVAENSVVISNGDINLSLRKAKKRAFQLEEGEETEPDCKYSKKHWKSRENNNNNEKVL 146
++GVA V + + R KK+ + ++ ++T KK +++ K
Sbjct: 5 DKGVAMEKVHVITEKESAWKRGRKKKTTKKKKKKKTTMK---KKKKTTTKKKTTTKTKKR 61
Query: 147 DLEPKAVTDQTVSKKNKRKNKATCGTVGDDNEEAKRKSPKKKEKCEYKKKAKNPKSPKVQ 206
K T T +K K K K + E+ K K KKK+K + KKK N K ++
Sbjct: 62 TTTTKKTTTTTTKEKEKEKEKEKEKEKEKEKEKEKEKKKKKKKKKKKKKKKLNAKVCGLE 121
Query: 207 AVKDWANQ-RCSSPKGSARNSLVKAKRKGSVSVCSKESPSSSSESESCDESISDGPS 262
+ W+ ++ +G + S+V+A VS+ S SPS S E G S
Sbjct: 122 -IASWSEMTTAAAGEGEEQGSMVQA---AGVSI-SNSSPSRSDGKEGWTRFTGHGES 173
Score = 35.0 bits (79), Expect = 0.19
Identities = 44/204 (21%), Positives = 76/204 (37%), Gaps = 28/204 (13%)
Query: 121 ETEPDCKYSKKHWKSRENNNNNEKVLDLEPKAVTDQTVSKKNKRKNKATCGTVGDDNEEA 180
E E K +K K+ + + + + K T + + K K++ T T +E
Sbjct: 18 EKESAWKRGRKK-KTTKKKKKKKTTMKKKKKTTTKKKTTTKTKKRTTTTKKTTTTTTKEK 76
Query: 181 KRKSPKKKEKCEYKKKAKNPKSPKVQAVKDWANQRCSSPKGSARNSLVKAKRKGSVSVCS 240
+++ K+KEK + K+K K + K + K K K+K + VC
Sbjct: 77 EKEKEKEKEKEKEKEKEKEKEKKKKKKKKK-----------------KKKKKKLNAKVCG 119
Query: 241 KESPSSSSESESCDESISDGPSKVTLEARNSSEKLPTELSKEEPSTKNTTADKLAIKLGF 300
E S S + + + S V + S P+ +E T+ T G
Sbjct: 120 LEIASWSEMTTAAAGEGEEQGSMVQAAGVSISNSSPSRSDGKEGWTRFT---------GH 170
Query: 301 SLTPSKGKTSGTTSSSSDSSAESD 324
+P++ KT G S+ A D
Sbjct: 171 GESPTRFKT-GRLYPLSEKKANFD 193
>gi|169167062 PREDICTED: hypothetical protein LOC285556 [Homo
sapiens]
Length = 1826
Score = 45.1 bits (105), Expect = 2e-04
Identities = 35/114 (30%), Positives = 47/114 (41%), Gaps = 3/114 (2%)
Query: 268 ARNSSEKLPTELSKEEPSTKNTTADKLAIKLGFSLTPSKGKTSGTTSSSSDSSAESDDQC 327
+R+ EK E S + PS +N A + S + G S ++SSS + AE D
Sbjct: 258 SRSPKEKAQDEPSSKTPSPQNNPASSQLSRSQHSASEEGGNFSSSSSSSPMNKAEEDGLS 317
Query: 328 LMSSSTPECAAGFLKTVGLFAG-RGRPGPGLSSQTAGAAGWRRSGSNGGGQAPG 380
M ST + G L T G G Q G G + SG GGG+ G
Sbjct: 318 KMEDST--TSTGALATSSSSLGFESESGESEGCQAVGGEGEKISGGGGGGKGGG 369
>gi|113416182 PREDICTED: hypothetical protein LOC285556 [Homo
sapiens]
Length = 1826
Score = 45.1 bits (105), Expect = 2e-04
Identities = 35/114 (30%), Positives = 47/114 (41%), Gaps = 3/114 (2%)
Query: 268 ARNSSEKLPTELSKEEPSTKNTTADKLAIKLGFSLTPSKGKTSGTTSSSSDSSAESDDQC 327
+R+ EK E S + PS +N A + S + G S ++SSS + AE D
Sbjct: 258 SRSPKEKAQDEPSSKTPSPQNNPASSQLSRSQHSASEEGGNFSSSSSSSPMNKAEEDGLS 317
Query: 328 LMSSSTPECAAGFLKTVGLFAG-RGRPGPGLSSQTAGAAGWRRSGSNGGGQAPG 380
M ST + G L T G G Q G G + SG GGG+ G
Sbjct: 318 KMEDST--TSTGALATSSSSLGFESESGESEGCQAVGGEGEKISGGGGGGKGGG 369
>gi|113415686 PREDICTED: hypothetical protein LOC285556 [Homo
sapiens]
Length = 1826
Score = 45.1 bits (105), Expect = 2e-04
Identities = 35/114 (30%), Positives = 47/114 (41%), Gaps = 3/114 (2%)
Query: 268 ARNSSEKLPTELSKEEPSTKNTTADKLAIKLGFSLTPSKGKTSGTTSSSSDSSAESDDQC 327
+R+ EK E S + PS +N A + S + G S ++SSS + AE D
Sbjct: 258 SRSPKEKAQDEPSSKTPSPQNNPASSQLSRSQHSASEEGGNFSSSSSSSPMNKAEEDGLS 317
Query: 328 LMSSSTPECAAGFLKTVGLFAG-RGRPGPGLSSQTAGAAGWRRSGSNGGGQAPG 380
M ST + G L T G G Q G G + SG GGG+ G
Sbjct: 318 KMEDST--TSTGALATSSSSLGFESESGESEGCQAVGGEGEKISGGGGGGKGGG 369
>gi|87299628 biorientation of chromosomes in cell division 1-like
[Homo sapiens]
Length = 3051
Score = 45.1 bits (105), Expect = 2e-04
Identities = 60/230 (26%), Positives = 93/230 (40%), Gaps = 37/230 (16%)
Query: 108 KAKKRAFQLEEGEETEPD--------CKYSKKHWKSRENNNNNEKVLDLEPKAVTDQTVS 159
K K A EG ET P C + ++E+NN L L K V ++
Sbjct: 259 KEKSTADSGGEGLETAPKSEEFSDLPCPVEEIKNYTKEHNN-----LILLNKDVQQESSE 313
Query: 160 KKNKRKNKATCGTVGDDNEEAKRKSPKKKEKCEYKKKAKNPKSPKVQAVKDWANQRCSSP 219
+KNK +K D NE+ +RK +KKEK E KK + KS Q VKD
Sbjct: 314 QKNKSTDKGE--KKPDSNEKGERKK-EKKEKTE-KKFDHSKKSEDTQKVKD--------- 360
Query: 220 KGSARNSLVKAKRKGSVSVCSKESPSSSSESESCDESIS------DGPSKVTLEARNSSE 273
K K S+ + S+++ + + E E S DG + +T+ + ++S+
Sbjct: 361 -----EKQAKEKEVESLKLPSEKNSNKAKTVEGTKEDFSLIDSDVDGLTDITVSSVHTSD 415
Query: 274 KLPTELSKEEPSTKNTTADKLAIKLGFSLTPSKGKTSGTTSSSSDSSAES 323
E EE + + ++ I + KT TS SS+ +S
Sbjct: 416 LSSFEEDTEEEVVTSDSMEEGEITSDDEEKNKQNKTKTQTSDSSEGKTKS 465
Score = 40.0 bits (92), Expect = 0.006
Identities = 51/211 (24%), Positives = 80/211 (37%), Gaps = 34/211 (16%)
Query: 104 LSLRKAKKRAFQLEEGEETEPDCKYSKKHWKSRENNNNNEKVLDLEPKAVTDQTVSKKNK 163
LS++ K + G+ETE S+K K EN + + K +D +K+K
Sbjct: 739 LSVKHKYKGDCMHKTGDETE--LHSSEKGLKVEENIQKQSQ----QTKLSSDDKTERKSK 792
Query: 164 RKNKATCGTVGDDNEEAKRKSPKKKEKCEYKKKAKNPKSPKVQAVKDWANQRCSSPKGSA 223
+N+ +G D + K E +K N K ++ A K A +
Sbjct: 793 HRNERKLSVLGKDGKPVSEYIIKTDENV---RKENNKKERRLSAEKTKAEHK-------- 841
Query: 224 RNSLVKAKRKGSVSVCSKESPSSSSESESCD-ESISDGPSKVTLEARNSSEKLPTE--LS 280
R+ S S K+S S + S S K +++ N L E +
Sbjct: 842 -------SRRSSDSKIQKDSLGSKQHGITLQRRSESYSEDKCDMDSTNMDSNLKPEEVVH 894
Query: 281 KEEPSTKNTTADKLAIKLGFSLTPSKGKTSG 311
KE+ TK+ +KL +K SK KT G
Sbjct: 895 KEKRRTKSLLEEKLVLK-------SKSKTQG 918
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 45.1 bits (105), Expect = 2e-04
Identities = 37/183 (20%), Positives = 78/183 (42%), Gaps = 9/183 (4%)
Query: 110 KKRAFQLEEGEETEPDCKYSKKHWKSRENNNNNEKVLDLEPKAVTDQTVSKKNKRKNKAT 169
K+R E+ +E + + + K+H K R+ E+ + E + + + +K K+ K+
Sbjct: 419 KEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSR 478
Query: 170 CGTVGDDNEEAKRKSPKKKEKCEYKKKAKNPKSPKVQAVKDWANQRCSSPKGSARNSLVK 229
+ R S +++ + + +++P++ K K + R SP+ + +
Sbjct: 479 TPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRK---SSRSPSPRSRNKKDKKR 535
Query: 230 AKRKGSVSVCSKESPSSSSESESCDESISDGPSKVTLEARNSSEKLPTELSKEEPSTKNT 289
K + +S + S+S S D DG K+ +NS+ E +KE S+ +
Sbjct: 536 EKERDHISERRERERSTSMRKSSNDR---DGKEKL---EKNSTSLKEKEHNKEPDSSVSK 589
Query: 290 TAD 292
D
Sbjct: 590 EVD 592
Score = 29.6 bits (65), Expect = 7.9
Identities = 55/234 (23%), Positives = 91/234 (38%), Gaps = 18/234 (7%)
Query: 107 RKAKKRAFQLEEGEETEPDCKYSKK-HWKSRENNNNNEKVLDLEPKAVTDQTVSK---KN 162
RK++ R+ ++ ++T K ++ K RE EK + E + ++ K K+
Sbjct: 365 RKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKD 424
Query: 163 KRKNKATCGTVGDDNEEAKRKSPKKKEKCEYKKKAKNPKSPKVQAVKDWANQRCSSP--- 219
+ K+K + E K + K+KEK + K+K + K K +++ +P
Sbjct: 425 REKDKEKDREREREKEHEKDRD-KEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRS 483
Query: 220 -KGSARNSLVKAKRKGSVSVCSKESPSSS------SESESCDESISDGPSKVTLEARNSS 272
S R+ +R+ S S SP +S S S + K E + S
Sbjct: 484 YNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHIS 543
Query: 273 EKLPTELSKEEPSTKNTTADKLAIKLGFSLTPSKGKTSGTTSSSSDSSAESDDQ 326
E+ E S + N K KL + T K K SS S E DD+
Sbjct: 544 ERRERERSTSMRKSSNDRDGK--EKLEKNSTSLKEKEHNKEPDSS-VSKEVDDK 594
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 45.1 bits (105), Expect = 2e-04
Identities = 37/183 (20%), Positives = 78/183 (42%), Gaps = 9/183 (4%)
Query: 110 KKRAFQLEEGEETEPDCKYSKKHWKSRENNNNNEKVLDLEPKAVTDQTVSKKNKRKNKAT 169
K+R E+ +E + + + K+H K R+ E+ + E + + + +K K+ K+
Sbjct: 303 KEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSR 362
Query: 170 CGTVGDDNEEAKRKSPKKKEKCEYKKKAKNPKSPKVQAVKDWANQRCSSPKGSARNSLVK 229
+ R S +++ + + +++P++ K K + R SP+ + +
Sbjct: 363 TPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRK---SSRSPSPRSRNKKDKKR 419
Query: 230 AKRKGSVSVCSKESPSSSSESESCDESISDGPSKVTLEARNSSEKLPTELSKEEPSTKNT 289
K + +S + S+S S D DG K+ +NS+ E +KE S+ +
Sbjct: 420 EKERDHISERRERERSTSMRKSSNDR---DGKEKL---EKNSTSLKEKEHNKEPDSSVSK 473
Query: 290 TAD 292
D
Sbjct: 474 EVD 476
Score = 29.6 bits (65), Expect = 7.9
Identities = 55/234 (23%), Positives = 91/234 (38%), Gaps = 18/234 (7%)
Query: 107 RKAKKRAFQLEEGEETEPDCKYSKK-HWKSRENNNNNEKVLDLEPKAVTDQTVSK---KN 162
RK++ R+ ++ ++T K ++ K RE EK + E + ++ K K+
Sbjct: 249 RKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKD 308
Query: 163 KRKNKATCGTVGDDNEEAKRKSPKKKEKCEYKKKAKNPKSPKVQAVKDWANQRCSSP--- 219
+ K+K + E K + K+KEK + K+K + K K +++ +P
Sbjct: 309 REKDKEKDREREREKEHEKDRD-KEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRS 367
Query: 220 -KGSARNSLVKAKRKGSVSVCSKESPSSS------SESESCDESISDGPSKVTLEARNSS 272
S R+ +R+ S S SP +S S S + K E + S
Sbjct: 368 YNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHIS 427
Query: 273 EKLPTELSKEEPSTKNTTADKLAIKLGFSLTPSKGKTSGTTSSSSDSSAESDDQ 326
E+ E S + N K KL + T K K SS S E DD+
Sbjct: 428 ERRERERSTSMRKSSNDRDGK--EKLEKNSTSLKEKEHNKEPDSS-VSKEVDDK 478
>gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 1 [Homo sapiens]
Length = 559
Score = 44.3 bits (103), Expect = 3e-04
Identities = 53/212 (25%), Positives = 85/212 (40%), Gaps = 25/212 (11%)
Query: 127 KYSKKHWKSRENNNNNEKVLDLEPKAVTDQTVSKKNKRKNKATCGTVGDDNEEAKRKSPK 186
K SK H ++E+ K D E K+ + + + ++ + +K T +G+ + K+P
Sbjct: 190 KTSKPHKVTKEHRERPRK--DSESKS-SSKELEREQAKSSKDTSRKLGEGRLPKEEKAPP 246
Query: 187 KKEKCEYKKKAKN--------------PKSPKVQAVKDWANQRCSSPKGSARNSLVKAKR 232
K + K A P P SPK SA+ K+
Sbjct: 247 PKAAFKEPKMALKETKLESTSPKGGPPPPPPPPPRASSKRPATADSPKPSAKKQK-KSSS 305
Query: 233 KGSVSVCSKESPSSSSESESCDESISDGPSKVTLEARNSSEKLPTELSKEEPSTKNTTAD 292
KGS S +SSS S S + D S T + +E P E K ++ + D
Sbjct: 306 KGSRSAPGTSPRTSSSSSFSDKKPAKDKSS--TRGEKVKAESEPREAKKALEVEESNSED 363
Query: 293 KLAIKLGFSLTPSKGKTSGTTSSSSDSSAESD 324
+ + K + S + +SSSSDSS++SD
Sbjct: 364 EASFK-----SESAQSSPSNSSSSSDSSSDSD 390
Score = 38.1 bits (87), Expect = 0.022
Identities = 36/163 (22%), Positives = 58/163 (35%), Gaps = 5/163 (3%)
Query: 164 RKNKATCGTVGDDNEEAKRKSPKK--KEKCEYKKKAKNPKSPKVQAVKDWANQRCSSPKG 221
+K K + G+ + E +K P K KE E +K KS + ++ A + +
Sbjct: 173 KKTKPSHGSKDANKESSKTSKPHKVTKEHRERPRKDSESKSSSKELEREQAKSSKDTSRK 232
Query: 222 SARNSLVKAKRKGSVSVCSKESPSSSSESESCDESISDGPSKVTLEARNSSEKLPTELSK 281
L K ++ KE + E++ S GP +S K P
Sbjct: 233 LGEGRLPKEEKAPPPKAAFKEPKMALKETKLESTSPKGGPPPPPPPPPRASSKRPATADS 292
Query: 282 EEPSTKNTTADKLAIKLGFSLTPSKGKTSGTTSSSSDSSAESD 324
+PS K K + G P + ++SS SD D
Sbjct: 293 PKPSAKK---QKKSSSKGSRSAPGTSPRTSSSSSFSDKKPAKD 332
Score = 37.4 bits (85), Expect = 0.038
Identities = 36/163 (22%), Positives = 70/163 (42%), Gaps = 21/163 (12%)
Query: 179 EAKRKSPKKKEKCEYKKKAKNP-KSPKVQAVKDWANQRCSSPKGSARNSLVKAKRKGSVS 237
++ + S KK++K K P SP+ + +++++ + K S R VKA+ + +
Sbjct: 291 DSPKPSAKKQKKSSSKGSRSAPGTSPRTSSSSSFSDKKPAKDKSSTRGEKVKAESEPREA 350
Query: 238 VCSKESPSSSSESESC--DESISDGPSKVTLEARNSSE---------------KLPTELS 280
+ E S+SE E+ ES PS + + +SS+ + +L
Sbjct: 351 KKALEVEESNSEDEASFKSESAQSSPSNSSSSSDSSSDSDFEPSQNHSQGPLRSMVEDLQ 410
Query: 281 KEEPSTKNTTADKLAIKLGFSLTPSKGKTSGTTSSSSDSSAES 323
EE ++++ + A P + + S SD+SA+S
Sbjct: 411 SEESDEDDSSSGEEA---AGKTNPGRDSRLSFSDSESDNSADS 450
Score = 33.5 bits (75), Expect = 0.55
Identities = 40/156 (25%), Positives = 60/156 (38%), Gaps = 12/156 (7%)
Query: 241 KESPSSSSESESCDESISDGPSKVTLEAR------NSSEKLPTELSKEEPSTKNTTADKL 294
K PS S+ + + S + P KVT E R + S+ EL +E+ + T+ KL
Sbjct: 174 KTKPSHGSKDANKESSKTSKPHKVTKEHRERPRKDSESKSSSKELEREQAKSSKDTSRKL 233
Query: 295 AIKLGFSLTPSKGKTSGTTSSSSDSSAESDDQCLMSSSTPECAAGFLKTVGLFAGRGRPG 354
G P + K ++ + + L S+S P+ A RP
Sbjct: 234 ----GEGRLPKEEKAPPPKAAFKEPKMALKETKLESTS-PKGGPPPPPPPPPRASSKRPA 288
Query: 355 PGLSSQTAGAAGWRRSGSNGGGQAPGASPSVSLPAS 390
S A ++S S G APG SP S +S
Sbjct: 289 TA-DSPKPSAKKQKKSSSKGSRSAPGTSPRTSSSSS 323
>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
Length = 2426
Score = 44.3 bits (103), Expect = 3e-04
Identities = 45/205 (21%), Positives = 86/205 (41%), Gaps = 23/205 (11%)
Query: 117 EEGEETEPDCKYSKKHWKSRENNNNNEKVLDLEPKAVTDQTVSKKNKRKNKATCGTVGDD 176
EE ++ E K H KS++N N ++ E + D ++ ++KR + +
Sbjct: 1785 EEKDDYEIFVKVKDTHEKSKKNKNRDKG----EKEKKRDSSLRSRSKRSKSS-------E 1833
Query: 177 NEEAKRKSPKKKEKCEYKKKAKNPKSPKVQAVKDWANQRC--SSPKGSARNSLVKAKRKG 234
++ KR S + + K+K+ +S + +R S K R S+ K KRK
Sbjct: 1834 HKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKR 1893
Query: 235 SVSVCSKESPSSSSESESCDESISDGPSKVTLEARNSSEKLPTELSKEEPSTKNTTADKL 294
S SK S S D ++ T+ AR+ + P+ S+ ++ + +
Sbjct: 1894 SPKHRSKSRERKRKRSSSRD-------NRKTVRARS---RTPSRRSRSHTPSRRRRSRSV 1943
Query: 295 AIKLGFSLTPSKGKTSGTTSSSSDS 319
+ FS++PS+ + + S + S
Sbjct: 1944 GRRRSFSISPSRRSRTPSRRSRTPS 1968
>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
Length = 2303
Score = 44.3 bits (103), Expect = 3e-04
Identities = 45/205 (21%), Positives = 86/205 (41%), Gaps = 23/205 (11%)
Query: 117 EEGEETEPDCKYSKKHWKSRENNNNNEKVLDLEPKAVTDQTVSKKNKRKNKATCGTVGDD 176
EE ++ E K H KS++N N ++ E + D ++ ++KR + +
Sbjct: 1785 EEKDDYEIFVKVKDTHEKSKKNKNRDKG----EKEKKRDSSLRSRSKRSKSS-------E 1833
Query: 177 NEEAKRKSPKKKEKCEYKKKAKNPKSPKVQAVKDWANQRC--SSPKGSARNSLVKAKRKG 234
++ KR S + + K+K+ +S + +R S K R S+ K KRK
Sbjct: 1834 HKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKR 1893
Query: 235 SVSVCSKESPSSSSESESCDESISDGPSKVTLEARNSSEKLPTELSKEEPSTKNTTADKL 294
S SK S S D ++ T+ AR+ + P+ S+ ++ + +
Sbjct: 1894 SPKHRSKSRERKRKRSSSRD-------NRKTVRARS---RTPSRRSRSHTPSRRRRSRSV 1943
Query: 295 AIKLGFSLTPSKGKTSGTTSSSSDS 319
+ FS++PS+ + + S + S
Sbjct: 1944 GRRRSFSISPSRRSRTPSRRSRTPS 1968
>gi|41055989 M-phase phosphoprotein 8 [Homo sapiens]
Length = 860
Score = 43.9 bits (102), Expect = 4e-04
Identities = 55/213 (25%), Positives = 91/213 (42%), Gaps = 18/213 (8%)
Query: 79 DCLRVKLEERG-VAENSVVISNGDIN-LSLRKAKKRA-FQLEEGEETEPDCKYSKKHWKS 135
DC V LE R +AEN DI LSL A ++ ET+ D KK K
Sbjct: 98 DCKEVLLEFRKKIAENKAKAVRKDIQRLSLNNDIFEANSDSDQQSETKEDTSPKKKKKKL 157
Query: 136 RENNNNNEKVLDLEPKAVTDQTVSKKNKRKNKATCGTVGDDNEEAKRKSPKKKEKCEYKK 195
R+ + DL+ K + K+K +++ ++ D KR S K+E K
Sbjct: 158 RQREEKSPD--DLKKKKAKAGKLKDKSKPDLESSLESLVFDLRTKKRISEAKEE----LK 211
Query: 196 KAKNPKSPKVQAVKDWANQRCSSPKGSARNSLVKAKRKGSVSVCSKESPSSSSESESCDE 255
++K PK +V+ K+ + KG R+ K + + +K+ S+ ES
Sbjct: 212 ESKKPKKDEVKETKELKKVK----KGEIRDLKTKTREDPKENRKTKKEKFVESQVESESS 267
Query: 256 SISDGPSKVTLEARNSSEKLPTELSKEEPSTKN 288
++D P + SE L ++ +E+ +TK+
Sbjct: 268 VLNDSPF-----PEDDSEGLHSDSREEKQNTKS 295
>gi|27262628 nuclear autoantigenic sperm protein isoform 2 [Homo
sapiens]
Length = 788
Score = 43.9 bits (102), Expect = 4e-04
Identities = 46/177 (25%), Positives = 72/177 (40%), Gaps = 21/177 (11%)
Query: 117 EEGEETEPDCKYSKKHWKSRENNNN-----NEKVLDLEPKAVTDQTVSKKNKRKNKATCG 171
EEGE+TE + ENN+N E++ + A+ ++ +KK + K+ A
Sbjct: 118 EEGEKTEDESLV--------ENNDNIDEEAREELREQVYDAMGEKEEAKKTEDKSLAKPE 169
Query: 172 TVGDDNEEAKRKSPKKKEKCEYKKKAKNPKSPKVQAVKDWANQRCSSPKGSAR----NSL 227
T D E+ +E + K A+ P+ KV DW + KG A N
Sbjct: 170 T---DKEQDSEMEKGGREDMDISKSAEEPQE-KVDLTLDWLTETSEEAKGGAAPEGPNEA 225
Query: 228 VKAKRKGSVSVCSKESPSSSSESESCDESISDGPSKVTLEARNSSEKLPTELSKEEP 284
K V E S S ++ +E G + E S E+ P E+S+E+P
Sbjct: 226 EVTSGKPEQEVPDAEEEKSVSGTDVQEECREKGGQEKQGEVIVSIEEKPKEVSEEQP 282
>gi|27262634 nuclear autoantigenic sperm protein isoform 1 [Homo
sapiens]
Length = 790
Score = 43.9 bits (102), Expect = 4e-04
Identities = 46/177 (25%), Positives = 72/177 (40%), Gaps = 21/177 (11%)
Query: 117 EEGEETEPDCKYSKKHWKSRENNNN-----NEKVLDLEPKAVTDQTVSKKNKRKNKATCG 171
EEGE+TE + ENN+N E++ + A+ ++ +KK + K+ A
Sbjct: 120 EEGEKTEDESLV--------ENNDNIDEEAREELREQVYDAMGEKEEAKKTEDKSLAKPE 171
Query: 172 TVGDDNEEAKRKSPKKKEKCEYKKKAKNPKSPKVQAVKDWANQRCSSPKGSAR----NSL 227
T D E+ +E + K A+ P+ KV DW + KG A N
Sbjct: 172 T---DKEQDSEMEKGGREDMDISKSAEEPQE-KVDLTLDWLTETSEEAKGGAAPEGPNEA 227
Query: 228 VKAKRKGSVSVCSKESPSSSSESESCDESISDGPSKVTLEARNSSEKLPTELSKEEP 284
K V E S S ++ +E G + E S E+ P E+S+E+P
Sbjct: 228 EVTSGKPEQEVPDAEEEKSVSGTDVQEECREKGGQEKQGEVIVSIEEKPKEVSEEQP 284
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 43.5 bits (101), Expect = 5e-04
Identities = 44/218 (20%), Positives = 92/218 (42%), Gaps = 17/218 (7%)
Query: 109 AKKRAFQLEEGEETEPDCKYSKKHWKSRENNNNNEKVLDLEPKAVTDQTVSKK-NKRKNK 167
+K+R + E C+ S+ K R++ + P + S+ NK +++
Sbjct: 492 SKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRS------PSKERQRRQSRSPNKERDR 545
Query: 168 ATCGTVGDDNEEAKRKSP-KKKEKCEYKKKAKNPKSPKVQAVKDWANQ-RCSSPKGSARN 225
+ + ++ E + +SP K++++ ++ +K + + ++ + + R SP +
Sbjct: 546 SQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGY 605
Query: 226 SLVKAKRKGSVSVCSKESPSSSSESESCDESISDGPSKVTLEARNSSEKLPTELSKEEPS 285
S +A K S+ + S+S S PS+ T+ ++ PT S
Sbjct: 606 SRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSS---L 662
Query: 286 TKNTTADKLAIKLGFSLTPSKGKTSGTTSSSSDSSAES 323
++N T K + S +PS + G T S DS A++
Sbjct: 663 SQNRTPSKTS-----SHSPSTFPSGGQTLSQDDSQADA 695
Score = 38.5 bits (88), Expect = 0.017
Identities = 66/291 (22%), Positives = 112/291 (38%), Gaps = 50/291 (17%)
Query: 217 SSPKGSARNSLVKAKRKGSVSVCSKESPSSSSESESCDESISDGPSKV-----TLEARNS 271
SSPK S++ S+ A S+ + P+S ++S + S P+K ++ + +S
Sbjct: 2 SSPKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSS 61
Query: 272 SEKLPTELSKEEPSTKNTTADKLAIKLGFSLTPSKGKTSGTTSSSSDSSAESDDQCLMSS 331
S+ + +K PS + ++ ++ K + TPS+ T TS +S + SD +C
Sbjct: 62 SKSTKSTSTKRAPSNRPSSRSRVRSK---ARTPSRVSTDTRTSKASKA---SDVRCHQRR 115
Query: 332 STPECAAGFLKTVGLFAGRGRPGPGLSSQTAGAAGWRRSGSNG----GGQAPGASPSVSL 387
T RGR PG + R+ + G G PG + V
Sbjct: 116 GT--------------HSRGRT-PGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRT 160
Query: 388 PASLGRGWGREENLFSWKGAKGRGM-RGRGRGRGHPVSCVVNRSTDNQRQQQLNDVVKNS 446
P S KG++G+ R R R S N S + R + + ++S
Sbjct: 161 PTS------------QQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSS 208
Query: 447 STII-------QNPVETPKKDYSLLPLLAAAPQVGEKIAFKLLELTSSYSP 490
+ Q P P K+ S P +++ +V + SYSP
Sbjct: 209 ELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSP 259
Score = 31.6 bits (70), Expect = 2.1
Identities = 52/216 (24%), Positives = 83/216 (38%), Gaps = 43/216 (19%)
Query: 199 NPKSP-KVQAVKDWANQRCSSPK--GSARNSLVK-AKRKGSVSVCSKESPSSSSESESCD 254
+PK P +++ K R P ++RNS++ + K + S +K +PS+ S S
Sbjct: 25 DPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSSSKSTKSTSTKRAPSNRPSSRSRV 84
Query: 255 ESISDGPSKVTLEARNSSEKLPTELSKEEPSTKNTTADKLAIKLGFSLTPSKGKTSGTTS 314
S + PS+V+ + R S +++ + T S+G+T G
Sbjct: 85 RSKARTPSRVSTDTRTSKASKASDVRCHQRRG----------------THSRGRTPGRRG 128
Query: 315 SSSDSSAESDDQCLMSSSTPECAAGFLKTVGLFAGRGRPGPGLSSQTAGAAGWRRSGSNG 374
S S + S +STP G ++T G G +SQ G+ R S G
Sbjct: 129 SRSSKRSPS------RASTP----GRIRTHGARPGMASRVRTPTSQQKGS----RGKSYG 174
Query: 375 GGQAPGASPSVSLPASL---------GRGWGREENL 401
+ S S P +L G G GR L
Sbjct: 175 RPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSEL 210
>gi|168229156 NFKB activating protein [Homo sapiens]
Length = 415
Score = 43.5 bits (101), Expect = 5e-04
Identities = 40/168 (23%), Positives = 72/168 (42%), Gaps = 12/168 (7%)
Query: 150 PKAVTDQTVSKKNKRKNKATCGTVGDDNEEAKRKSPKKKEKCEYKKKAKNPKSPKVQAVK 209
P+ +D+ +++ K+T + EE K+KS + KE+ + ++K K+ K + +
Sbjct: 153 PEPDSDEHTPVEDEEPKKSTT-SASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSE 211
Query: 210 DWANQRCSSPKGS-------ARNSLVKAKRKGSVSVCSKESPSSSSESESCDESISDGPS 262
D + S S A+ + K K+K S K+ S S ES D S +
Sbjct: 212 DSDSDSDSETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQE 271
Query: 263 KV---TLEARNSSEKLPTELSKEEPSTKNTTADKLAIKLGFSLTPSKG 307
+ + R +E+ + E P T + DK + G +L P +G
Sbjct: 272 EFLENPWKDRTKAEEPSDLIGPEAPKTLTSQDDK-PLNYGHALLPGEG 318
>gi|239744133 PREDICTED: hypothetical protein [Homo sapiens]
Length = 375
Score = 43.5 bits (101), Expect = 5e-04
Identities = 38/184 (20%), Positives = 71/184 (38%), Gaps = 7/184 (3%)
Query: 160 KKNKRKNKATCGTVGDDNEEAKRKSPKKKEKCEYKKKAKNPKSPKVQAVKDWANQRCSSP 219
+ ++ + +C T + +S + C + + S Q+ + + CS
Sbjct: 136 QSSRTSSTCSCQTSRTSSTSCSYQSSRTSSTCSCQSSGTSSTSCNWQSSR--TSSTCSCQ 193
Query: 220 KGSARNSLVKAKRKGSVSVCSKESPSSSSESESCDESISDGPSKVTLEARNSSEKLPTEL 279
++ + G+ S CS +S +SS S SC S G S + SS T
Sbjct: 194 SSGTSSTSYSCQSSGTSSTCSCQSSGTSSTSCSCQ---SSGTSSTC--SCQSSGTSSTSC 248
Query: 280 SKEEPSTKNTTADKLAIKLGFSLTPSKGKTSGTTSSSSDSSAESDDQCLMSSSTPECAAG 339
S + T +T + + + S + TS T S S ++ + C S ++ C+
Sbjct: 249 SWQSSRTSSTCSCQSSRTSSTSCSCQSSGTSSTCSCQSSGTSSTSCSCQSSRTSSTCSCQ 308
Query: 340 FLKT 343
F +T
Sbjct: 309 FSRT 312
Score = 37.0 bits (84), Expect = 0.049
Identities = 39/192 (20%), Positives = 72/192 (37%), Gaps = 10/192 (5%)
Query: 154 TDQTVS-KKNKRKNKATCGTVGDDNEEAKRKSPKKKEKCEYKKKAKNPKSPKVQAVKDWA 212
T T S + ++ + +C + G + +S + C + + S Q+ + +
Sbjct: 25 TSSTCSCQSSQTSSTCSCQSSGTSSTSCNWQSSRISSTCSCQSSGTSSTSCSCQSSETSS 84
Query: 213 NQRCSSPKGSARNSLVKAKRKGSVSVCSKESPSSSSESESCDESISDGPSKVTLEARNS- 271
C S S+ + + R S C +S +SS S SC S + S +R S
Sbjct: 85 TCSCQSSGTSSTSCSWQFSRTSSTCRC--QSSRTSSTSCSCQSSRTSSTSCSCQSSRTSS 142
Query: 272 ------SEKLPTELSKEEPSTKNTTADKLAIKLGFSLTPSKGKTSGTTSSSSDSSAESDD 325
S T S + T +T + + + S +TS T S S ++ +
Sbjct: 143 TCSCQTSRTSSTSCSYQSSRTSSTCSCQSSGTSSTSCNWQSSRTSSTCSCQSSGTSSTSY 202
Query: 326 QCLMSSSTPECA 337
C S ++ C+
Sbjct: 203 SCQSSGTSSTCS 214
>gi|156104891 general transcription factor IIF, polypeptide 1, 74kDa
[Homo sapiens]
Length = 517
Score = 43.5 bits (101), Expect = 5e-04
Identities = 72/304 (23%), Positives = 108/304 (35%), Gaps = 65/304 (21%)
Query: 109 AKKRAFQLEEGEETEPDCKYSKKHWKSRENNNNNEKVLDLEPKAVTDQTVSKKNKRKN-- 166
A+ R EE EE W+ R N+ ++ DQ ++ K K
Sbjct: 150 ARHRTLTAEEAEE----------EWERRNKVLNHFSIMQQRRLKDQDQDEDEEEKEKRGR 199
Query: 167 -KATCGTVGDDNEEAKRKS-------------PKKKEKCEYKK---KAKNPKSPKVQAVK 209
KA+ + D ++ + S PK K+K K K K K +A +
Sbjct: 200 RKASELRIHDLEDDLEMSSDASDASGEEGGRVPKAKKKAPLAKGGRKKKKKKGSDDEAFE 259
Query: 210 DWANQRCSSPKGSARNSLVKAKRKGSVSVCSKESPSSSSESESCDESISDGPSKVTLEAR 269
D S G V GS S S+E P S +++ +E G + + +
Sbjct: 260 D-------SDDGDFEGQEVDYMSDGSSS--SQEEPESKAKAPQQEEG-PKGVDEQSDSSE 309
Query: 270 NSSEKLPTELSKEEPSTKNTTADKLAIKLGFSLTPSKGKTSGTTSSSSDSSAESDDQCLM 329
S E+ P E KEE K TP + K +S SDSS ESD
Sbjct: 310 ESEEEKPPEEDKEEEEEKKAP------------TPQEKKRRKDSSEESDSSEESDIDSEA 357
Query: 330 SSSTPECAAGFLKTVGLFAGRGRPGPGLSSQTAGAAGWRRSGSNGGGQAPGASPSVSLPA 389
SS+ LF + + P + +G + R + G A G S S +L A
Sbjct: 358 SSA-------------LFMAKKKTPPKRERKPSGGSS-RGNSRPGTPSAEGGSTSSTLRA 403
Query: 390 SLGR 393
+ +
Sbjct: 404 AASK 407
Score = 34.7 bits (78), Expect = 0.25
Identities = 44/156 (28%), Positives = 67/156 (42%), Gaps = 10/156 (6%)
Query: 175 DDNEEAKRKSPKKKEKCEYK-KKAKNPKSPKVQAVKDWANQRCSSPKGS----ARNSLVK 229
D +EE++ + P +++K E + KKA P+ K + KD + + SS + A ++L
Sbjct: 306 DSSEESEEEKPPEEDKEEEEEKKAPTPQEKKRR--KDSSEESDSSEESDIDSEASSALFM 363
Query: 230 AKRKGSVSVCSKESPSSS-SESESCDESISDGPSKVTLEARNSSEKLPTELSKEEPSTKN 288
AK+K K S SS S S G + TL A S + +S E P+ K
Sbjct: 364 AKKKTPPKRERKPSGGSSRGNSRPGTPSAEGGSTSSTLRAAASKLEQGKRVS-EMPAAKR 422
Query: 289 TTADKLAIKLGFSLTPSKGKTSGTTSSSSDSSAESD 324
D L TP + + TT +S D D
Sbjct: 423 LRLDTGPQSLSGKSTP-QPPSGKTTPNSGDVQVTED 457
>gi|7661950 SH2 domain binding protein 1 [Homo sapiens]
Length = 1173
Score = 43.5 bits (101), Expect = 5e-04
Identities = 55/235 (23%), Positives = 97/235 (41%), Gaps = 26/235 (11%)
Query: 107 RKAKKRAFQLEEGEETEPDCKYSKKHWKSRENNNNNEKVLDLEPKAVTDQTVSKKNKRKN 166
R K F ++T+ D SKK K R + +E+ + ++ +K K++
Sbjct: 910 RSKKGGEFDEFVNDDTDDDLPISKK--KKRRKGSGSEQ------EGEDEEGGERKKKKRR 961
Query: 167 KATCGTVGDDNEEAKR-KSPKKKE--KCEYKKKAKNPKSPKVQAVKDWANQRCSSPKGSA 223
+ G G D++E + PKK+ K E KK K + P K + SS S+
Sbjct: 962 RHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPERLPPSMKGKIKSKAIISSSDDSS 1021
Query: 224 RNSLVKAKRKGSVSVCSKESPS---------SSSESESCDESISDGPSKVTLEARNSSEK 274
+K +G + S S +SSES+S DE+ + S+ R ++
Sbjct: 1022 DEDKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDS-DENQNKSGSEAGSPRRPRRQR 1080
Query: 275 LPTELSKEEPSTK-----NTTADKLAIKLGFSLTPSKGKTSGTTSSSSDSSAESD 324
+ ++PS K + +D +++ G S + S S S++S ES+
Sbjct: 1081 SDQDSDSDQPSRKRRPSGSEQSDNESVQSGRSHSGVSENDSRPASPSAESDHESE 1135
Score = 37.4 bits (85), Expect = 0.038
Identities = 51/240 (21%), Positives = 86/240 (35%), Gaps = 33/240 (13%)
Query: 155 DQTVSKKNKRKNKATCGTVGDDNEEAKRKS------PKKKEKCEYKKKAKNPKSPKVQAV 208
D +SKK KR+ + G+D E +RK PK +E + + PK K +
Sbjct: 928 DLPISKKKKRRKGSGSEQEGEDEEGGERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPP 987
Query: 209 KDWANQRCSSPKGSARNSLVKAKRKGSVSVCSKESPSSSSESESCDESISDGPSKVTLEA 268
K ++ +PK +K K K + S + S + + DE G + +
Sbjct: 988 K---AEKKKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADE----GHPRNSNSN 1040
Query: 269 RNSSEKLPTELSKEEPSTKNTTADKLAIKLGFSLTPSKGKTSGTTSSSSDS-------SA 321
+S E + S + +K + G P + ++ + S S S
Sbjct: 1041 SDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSE 1100
Query: 322 ESDDQCLMSSSTPECAAGFLKTVGLFAGRGRP-GPGLSSQTAGAAGWRRSGSNGGGQAPG 380
+SD++ + S + G+ RP P S G S + G GQ G
Sbjct: 1101 QSDNESVQSGRSHS---------GVSENDSRPASPSAESDHESERG---SDNEGSGQGSG 1148
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 43.5 bits (101), Expect = 5e-04
Identities = 40/125 (32%), Positives = 53/125 (42%), Gaps = 13/125 (10%)
Query: 222 SARNSLVKAKRKGSVSVCSKESPSSSSESESCDESISDGPS-------------KVTLEA 268
SA +L AK + S S S S SSSS S S S S G S +V L+
Sbjct: 2519 SALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKR 2578
Query: 269 RNSSEKLPTELSKEEPSTKNTTADKLAIKLGFSLTPSKGKTSGTTSSSSDSSAESDDQCL 328
S P E +E + T A + S + S +S ++SSSS SS+ S
Sbjct: 2579 VPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2638
Query: 329 MSSST 333
SSS+
Sbjct: 2639 SSSSS 2643
Score = 40.8 bits (94), Expect = 0.003
Identities = 41/160 (25%), Positives = 66/160 (41%), Gaps = 8/160 (5%)
Query: 201 KSPKVQAVKDWANQRCSSPKGSARNSLVKAKRKGSVSVCSKESPSSSSESESC----DES 256
+ P A A +R SS S+ +S + S S S S SS SE S + +
Sbjct: 2516 QQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVA 2575
Query: 257 ISDGPSKVTLEARNSSEKLPTELSKEEPSTKNTTADKLAIKLGFSLTPSKGKTSGTTSSS 316
+ PS E P E + + +++++ + S + S +S ++SSS
Sbjct: 2576 LKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2635
Query: 317 SDSSAESDDQCLMSSSTPECAAGFLKTVGLFAGRGRPGPG 356
S SS+ S SSS+P A + + A +P PG
Sbjct: 2636 SSSSSSSSS----SSSSPSPAKPGPQALPKPASPKKPPPG 2671
Score = 40.0 bits (92), Expect = 0.006
Identities = 48/211 (22%), Positives = 79/211 (37%), Gaps = 25/211 (11%)
Query: 119 GEETEPDCKYSKKHWKSRENNNNNEKVLDLEPKAVTDQTVSKKNKRKNKATCGTV----- 173
G E+ D K + + + + + + LD++P A + + +KA T
Sbjct: 1518 GSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRS 1577
Query: 174 ----GDDNEEAKRKSPKKKEKCEYKKKAKNPKS-PKVQAVKDWANQRCSSPKGSARNSLV 228
+ + R SP++ + P++ P+ Q+ D + + PK A +L
Sbjct: 1578 RSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPE----PKAPAPRALP 1633
Query: 229 KAKRKGSVSVCSKESPSSSSESESCDESISDGPSKVTLEARNSSEKLPTELSKEEPSTKN 288
+ R GS S SP SS +ES E P K R S S EP TK+
Sbjct: 1634 RRSRSGSSSKGRGPSPEGSSSTESSPEH----PPKSRTARRGSR-------SSPEPKTKS 1682
Query: 289 TTADKLAIKLGFSLTPSKGKTSGTTSSSSDS 319
T + K + S + S+S S
Sbjct: 1683 RTPPRRRSSRSSPELTRKARLSRRSRSASSS 1713
Score = 37.0 bits (84), Expect = 0.049
Identities = 27/113 (23%), Positives = 50/113 (44%), Gaps = 4/113 (3%)
Query: 160 KKNKRKNKATCGTVGDDNEEAKRKSPKKKEKCEYKKKAKNPKSPKVQAVKDWANQRCSSP 219
KK K+K++ E K+ S KKK + E + K + +SP ++ + +++
Sbjct: 189 KKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKK---- 244
Query: 220 KGSARNSLVKAKRKGSVSVCSKESPSSSSESESCDESISDGPSKVTLEARNSS 272
+ +R++ K + + S +S SSS S S S + L R+ S
Sbjct: 245 RKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPS 297
Score = 36.2 bits (82), Expect = 0.084
Identities = 36/191 (18%), Positives = 73/191 (38%), Gaps = 6/191 (3%)
Query: 184 SPKKKEKCEYKKKAKNPKSPKVQA--VKDWANQRCSSPKGSARNSLVKAKRKGSVSVCSK 241
S +K + ++++++ SP+++ + ++ SSP+ A++ L + S C K
Sbjct: 728 SERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPK 787
Query: 242 ESPSSSSESESCDESISDGPSKVTLEARNSSEKLPTELSKEEPSTKNTTADKLAIKLGFS 301
+ + S S+ SS P + + PS ++ ++ K+
Sbjct: 788 QKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSG 847
Query: 302 LTPSKGKTSGTTSSSSDSSAESDDQCLMSSSTPECAAGFLKTVGLFAGRGRPGPGLSSQT 361
P +G + + ++ S C SS PE + +T + G P + S T
Sbjct: 848 TPPRQGSIT-SPQANEQSVTPQRRSCFESSPDPELKS---RTPSRHSCSGSSPPRVKSST 903
Query: 362 AGAAGWRRSGS 372
RS S
Sbjct: 904 PPRQSPSRSSS 914
Score = 32.3 bits (72), Expect = 1.2
Identities = 36/157 (22%), Positives = 57/157 (36%), Gaps = 13/157 (8%)
Query: 184 SPKKKEKCEYKKKAKNPKSPKVQAVKDWANQRCSSPKGSARNSLVKAKRKGSVSVCSKES 243
SP+ EK ++ ++ SP+ + P+G R+ R+ +
Sbjct: 1732 SPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSR--SRSRREKTRTTRRRD 1789
Query: 244 PSSSSESESCDESISDGPSKVTLEARNSSEKLPTELSKEEPSTKNTTADKLAIKLGFSLT 303
S SS+S S S S+VT R S +++E S ++ + G S T
Sbjct: 1790 RSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRR-----RRGRSRT 1844
Query: 304 P------SKGKTSGTTSSSSDSSAESDDQCLMSSSTP 334
P S+ +TS S S A S TP
Sbjct: 1845 PPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTP 1881
Score = 31.6 bits (70), Expect = 2.1
Identities = 33/149 (22%), Positives = 53/149 (35%), Gaps = 4/149 (2%)
Query: 178 EEAKRKSPKKKEKCEYKKKAKNPKSPKVQAVKDWANQRCSSPKGSARNSLVKAKRKGSVS 237
E A ++ P + + P P K ++ SS S+ +S + S S
Sbjct: 2573 EVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSS 2632
Query: 238 VCSKESPSSSSESESCDESISDGPSKVTLEARNSSEKLPTELSKEEPSTKNTTADKLAIK 297
S S SSSS S S GP + + +S K P + S + D L
Sbjct: 2633 SSSSSSSSSSSSSSSSPSPAKPGPQAL---PKPASPKKPPPGERRSRSPRK-PIDSLRDS 2688
Query: 298 LGFSLTPSKGKTSGTTSSSSDSSAESDDQ 326
S +P + + S D + S ++
Sbjct: 2689 RSLSYSPVERRRPSPQPSPRDQQSSSSER 2717
Score = 30.8 bits (68), Expect = 3.5
Identities = 45/217 (20%), Positives = 87/217 (40%), Gaps = 28/217 (12%)
Query: 89 GVAENSVVISNGDINLSLRKAKKRAFQ--------LEEGEETEPDCKYSKKHWKS----R 136
G++++ V S+ D R+AK+ A + E P K KK K R
Sbjct: 140 GISDSYVDGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRR 199
Query: 137 ENNNNNEKVLDLEPKAVTDQTVSKKNKRKNKATCGTVGDDNEEAKRKSPKKKEKCEYKKK 196
+++ + K ++ S+ KRK+++ ++KRKS KK K + +
Sbjct: 200 SESSSPRRERKKSSKKKKHRSESESKKRKHRS-------PTPKSKRKSKDKKRK---RSR 249
Query: 197 AKNPKSPKVQAVKDWANQRCSSPKGSARNSLVKAKRKGSVSVCSKESPSSSSESESCDES 256
+ P +PK + + +S ++R+ A K + + SPS +S ++
Sbjct: 250 STTP-APKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDA 308
Query: 257 ISDGPSKVTLEARNSSEKLPTELSKEEPSTKNTTADK 293
P + + +S E + ++PS+ DK
Sbjct: 309 PFSEPGTTSTQRPSS-----PETATKQPSSPYEDKDK 340
>gi|239755326 PREDICTED: hypothetical protein [Homo sapiens]
Length = 375
Score = 43.1 bits (100), Expect = 7e-04
Identities = 38/184 (20%), Positives = 71/184 (38%), Gaps = 7/184 (3%)
Query: 160 KKNKRKNKATCGTVGDDNEEAKRKSPKKKEKCEYKKKAKNPKSPKVQAVKDWANQRCSSP 219
+ ++ + +C T + +S + C + + S Q+ + + CS
Sbjct: 136 QSSRTSSTCSCQTSRTSSTSCSYQSSRTSSTCSCQSSGTSSTSCNWQSSR--TSSTCSCQ 193
Query: 220 KGSARNSLVKAKRKGSVSVCSKESPSSSSESESCDESISDGPSKVTLEARNSSEKLPTEL 279
++ + G+ S CS +S +SS S SC S G S + SS T
Sbjct: 194 SSGTSSTSYSCQSSGTSSTCSCQSSGTSSTSCSCQ---SSGTSSTC--SCQSSGTSSTSC 248
Query: 280 SKEEPSTKNTTADKLAIKLGFSLTPSKGKTSGTTSSSSDSSAESDDQCLMSSSTPECAAG 339
S + T +T + + + S + TS T S S ++ + C S ++ C+
Sbjct: 249 SWQSSRTSSTCSCQSSGTSSTSCSCQSSGTSSTCSCQSSGTSSTSCSCQSSRTSSTCSCQ 308
Query: 340 FLKT 343
F +T
Sbjct: 309 FSRT 312
Score = 29.6 bits (65), Expect = 7.9
Identities = 29/123 (23%), Positives = 46/123 (37%), Gaps = 6/123 (4%)
Query: 216 CSSPKGSARNSLVKAKRKGSVSVCSKESPSSSSESESCDESISDGPSKVTLEARNSSEKL 275
CS ++ + + S CS +S +SS S SC S + SS
Sbjct: 40 CSCQSSGTSSTSCNWQSSRTSSTCSCQSSGTSSTSCSCQSSETSSTCSC-----QSSGTS 94
Query: 276 PTELSKEEPSTKNTTADKLAIKLGFSLTPSKGKTSGTTSSSSDSSAESDDQCLMS-SSTP 334
T S + T +T + + S + +TS T+ S S S C S +S+
Sbjct: 95 STSCSWQFSRTSSTCCCQSSRTSSTSCSCQSSRTSSTSCSCQSSRTSSTCSCQTSRTSST 154
Query: 335 ECA 337
C+
Sbjct: 155 SCS 157
>gi|13376245 zinc finger protein 403 [Homo sapiens]
Length = 697
Score = 43.1 bits (100), Expect = 7e-04
Identities = 51/213 (23%), Positives = 78/213 (36%), Gaps = 26/213 (12%)
Query: 120 EETEPDCKYSKKHWKSRENNNNNEKVLDLEPKAVTDQTVSKKNKRKNKAT---------- 169
EE + K KK K R+N N+ V D+ QT +K + K T
Sbjct: 362 EERVRELKQEKKRQK-RKNRRKNKCVCDIPTPL---QTADEKEVSQEKETDFIENSSCKA 417
Query: 170 CGTVGDDNEEAKRKSPKKKEKCEYKKKAKNPKSPKVQAVKDWANQRC--------SSPKG 221
CG+ D N + + C SPK+ K + C SS +G
Sbjct: 418 CGSTEDGNTCVEVIVTNENTSCTCPSSGNLLGSPKI---KKGLSPHCNGSDCGYSSSMEG 474
Query: 222 SARNSLVKAKRKGSVSVCSKESPSSSSESESCDESISDGPSKVTLEARNSSEKLPTELSK 281
S S + + +C+ + S C++ DG S V A + + K
Sbjct: 475 SETGSREGSDVACTEGICNHDEHGDDSCVHHCEDKEDDGDSCVECWANSEENDTKGKNKK 534
Query: 282 EEPSTKNTTADKLAIKLGFSLT-PSKGKTSGTT 313
++ +K D+ KLG +T P +TSG T
Sbjct: 535 KKKKSKILKCDEHIQKLGSCITDPGNRETSGNT 567
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.126 0.361
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,102,046
Number of Sequences: 37866
Number of extensions: 1194633
Number of successful extensions: 8494
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 80
Number of HSP's successfully gapped in prelim test: 529
Number of HSP's that attempted gapping in prelim test: 6413
Number of HSP's gapped (non-prelim): 1872
length of query: 576
length of database: 18,247,518
effective HSP length: 108
effective length of query: 468
effective length of database: 14,157,990
effective search space: 6625939320
effective search space used: 6625939320
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.