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Search of human proteins with 47519420
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|47519420 reticulon 4 interacting protein 1 precursor [Homo
sapiens]
(396 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|47519420 reticulon 4 interacting protein 1 precursor [Homo sa... 806 0.0
gi|194239674 crystallin, zeta isoform a [Homo sapiens] 93 5e-19
gi|13236495 crystallin, zeta isoform a [Homo sapiens] 93 5e-19
gi|194239676 crystallin, zeta isoform b [Homo sapiens] 89 9e-18
gi|28557745 zinc binding alcohol dehydrogenase domain containing... 73 5e-13
gi|18379349 vesicle amine transport protein 1 [Homo sapiens] 72 7e-13
gi|22538446 tumor protein p53 inducible protein 3 [Homo sapiens] 67 4e-11
gi|22538444 tumor protein p53 inducible protein 3 [Homo sapiens] 67 4e-11
gi|90669511 crystallin, zeta-like 1 [Homo sapiens] 66 6e-11
gi|226059159 prostaglandin reductase 1 isoform 1 [Homo sapiens] 56 5e-08
gi|226059133 prostaglandin reductase 1 isoform 1 [Homo sapiens] 56 5e-08
gi|24308257 vesicle amine transport protein 1 homolog (T. califo... 54 2e-07
gi|156627571 sorbitol dehydrogenase [Homo sapiens] 48 2e-05
gi|226056130 prostaglandin reductase 1 isoform 2 [Homo sapiens] 47 2e-05
gi|67078404 trans-2-enoyl-CoA reductase, mitochondrial isoform a... 47 4e-05
gi|197927207 crystallin, zeta isoform c [Homo sapiens] 44 3e-04
gi|67078406 trans-2-enoyl-CoA reductase, mitochondrial isoform b... 42 7e-04
gi|226246682 prostaglandin reductase 2 [Homo sapiens] 40 0.003
gi|226246680 prostaglandin reductase 2 [Homo sapiens] 40 0.003
gi|22748929 prostaglandin reductase 2 [Homo sapiens] 40 0.003
gi|71565152 class II alcohol dehydrogenase, pi subunit [Homo sap... 38 0.014
gi|7705925 dicarbonyl/L-xylulose reductase [Homo sapiens] 38 0.018
gi|41872631 fatty acid synthase [Homo sapiens] 33 0.59
gi|4501933 class I alcohol dehydrogenase, gamma subunit [Homo sa... 32 1.0
gi|71743840 class IV alcohol dehydrogenase, mu or sigma subunit ... 30 3.8
gi|222136615 exonuclease NEF-sp isoform 2 [Homo sapiens] 30 5.0
gi|222136613 exonuclease NEF-sp isoform 1 [Homo sapiens] 30 5.0
gi|189011544 ubiquitously transcribed tetratricopeptide repeat, ... 29 6.5
gi|7706523 WW domain-containing oxidoreductase isoform 1 [Homo s... 29 6.5
gi|18860884 WW domain-containing oxidoreductase isoform 2 [Homo ... 29 6.5
>gi|47519420 reticulon 4 interacting protein 1 precursor [Homo
sapiens]
Length = 396
Score = 806 bits (2083), Expect = 0.0
Identities = 396/396 (100%), Positives = 396/396 (100%)
Query: 1 MEFLKTCVLRRNACTAVCFWRSKVVQKPSVRRISTTSPRSTVMPAWVIDKYGKNEVLRFT 60
MEFLKTCVLRRNACTAVCFWRSKVVQKPSVRRISTTSPRSTVMPAWVIDKYGKNEVLRFT
Sbjct: 1 MEFLKTCVLRRNACTAVCFWRSKVVQKPSVRRISTTSPRSTVMPAWVIDKYGKNEVLRFT 60
Query: 61 QNMMMPIIHYPNEVIVKVHAASVNPIDVNMRSGYGATALNMKRDPLHVKIKGEEFPLTLG 120
QNMMMPIIHYPNEVIVKVHAASVNPIDVNMRSGYGATALNMKRDPLHVKIKGEEFPLTLG
Sbjct: 61 QNMMMPIIHYPNEVIVKVHAASVNPIDVNMRSGYGATALNMKRDPLHVKIKGEEFPLTLG 120
Query: 121 RDVSGVVMECGLDVKYFKPGDEVWAAVPPWKQGTLSEFVVVSGNEVSHKPKSLTHTQAAS 180
RDVSGVVMECGLDVKYFKPGDEVWAAVPPWKQGTLSEFVVVSGNEVSHKPKSLTHTQAAS
Sbjct: 121 RDVSGVVMECGLDVKYFKPGDEVWAAVPPWKQGTLSEFVVVSGNEVSHKPKSLTHTQAAS 180
Query: 181 LPYVALTAWSAINKVGGLNDKNCTGKRVLILGASGGVGTFAIQVMKAWDAHVTAVCSQDA 240
LPYVALTAWSAINKVGGLNDKNCTGKRVLILGASGGVGTFAIQVMKAWDAHVTAVCSQDA
Sbjct: 181 LPYVALTAWSAINKVGGLNDKNCTGKRVLILGASGGVGTFAIQVMKAWDAHVTAVCSQDA 240
Query: 241 SELVRKLGADDVIDYKSGSVEEQLKSLKPFDFILDNVGGSTETWAPDFLKKWSGATYVTL 300
SELVRKLGADDVIDYKSGSVEEQLKSLKPFDFILDNVGGSTETWAPDFLKKWSGATYVTL
Sbjct: 241 SELVRKLGADDVIDYKSGSVEEQLKSLKPFDFILDNVGGSTETWAPDFLKKWSGATYVTL 300
Query: 301 VTPFLLNMDRLGIADGMLQTGVTVGSKALKHFWKGVHYRWAFFMASGPCLDDIAELVDAG 360
VTPFLLNMDRLGIADGMLQTGVTVGSKALKHFWKGVHYRWAFFMASGPCLDDIAELVDAG
Sbjct: 301 VTPFLLNMDRLGIADGMLQTGVTVGSKALKHFWKGVHYRWAFFMASGPCLDDIAELVDAG 360
Query: 361 KIRPVIEQTFPFSKVPEAFLKVERGHARGKTVINVV 396
KIRPVIEQTFPFSKVPEAFLKVERGHARGKTVINVV
Sbjct: 361 KIRPVIEQTFPFSKVPEAFLKVERGHARGKTVINVV 396
>gi|194239674 crystallin, zeta isoform a [Homo sapiens]
Length = 329
Score = 92.8 bits (229), Expect = 5e-19
Identities = 90/358 (25%), Positives = 167/358 (46%), Gaps = 43/358 (12%)
Query: 42 VMPAWVIDKYGKNEVLRFTQNMMMPIIHYPNEVIVKVHAASVNPIDVNMRSGYGATALNM 101
+M A + ++G EVL+ ++ +PI ++V++KVHA VNP++ +RSG
Sbjct: 7 LMRAVRVFEFGGPEVLKLRSDIAVPIPK-DHQVLIKVHACGVNPVETYIRSG------TY 59
Query: 102 KRDPLHVKIKGEEFPLTLGRDVSGVVMECGLDVKYFKPGDEVWAAVPPWKQGTLSEFVVV 161
R PL P T G DV+GV+ G + FK GD V+ + G +E+ +
Sbjct: 60 SRKPL--------LPYTPGSDVAGVIEAVGDNASAFKKGDRVFTS--STISGGYAEYALA 109
Query: 162 SGNEVSHKPKSLTHTQAASLPYVALTAWSAINKVGGLNDKNCTGKRVLILGASGGVGTFA 221
+ + V P+ L Q A++ TA+ A+ + G+ VL+ GASGGVG A
Sbjct: 110 ADHTVYKLPEKLDFKQGAAIGIPYFTAYRALIHSACVK----AGESVLVHGASGGVGLAA 165
Query: 222 IQVMKAWDAHVTAVC-SQDASELVRKLGADDVIDYKSGSVEEQLKSL---KPFDFILDNV 277
Q+ +A+ + +++ ++V + GA +V +++ + +++K K D I++ +
Sbjct: 166 CQIARAYGLKILGTAGTEEGQKIVLQNGAHEVFNHREVNYIDKIKKYVGEKGIDIIIEML 225
Query: 278 GGSTETWAPDFLKKWSGATYVTLVTPFLLNMD-RLGIADGMLQTGVTVGSKALKHFWKGV 336
+ + D G + + + + ++ R +A GVT+ S + F
Sbjct: 226 --ANVNLSKDLSLLSHGGRVIVVGSRGTIEINPRDTMAKESSIIGVTLFSSTKEEF---- 279
Query: 337 HYRWAFFMASGPCLDDIAELVDAGKIRPVIEQTFPFSKVPEAFLKVERGH-ARGKTVI 393
++A + +G ++ G ++PVI +P KV EA + G A GK ++
Sbjct: 280 -QQYAAALQAG---------MEIGWLKPVIGSQYPLEKVAEAHENIIHGSGATGKMIL 327
>gi|13236495 crystallin, zeta isoform a [Homo sapiens]
Length = 329
Score = 92.8 bits (229), Expect = 5e-19
Identities = 90/358 (25%), Positives = 167/358 (46%), Gaps = 43/358 (12%)
Query: 42 VMPAWVIDKYGKNEVLRFTQNMMMPIIHYPNEVIVKVHAASVNPIDVNMRSGYGATALNM 101
+M A + ++G EVL+ ++ +PI ++V++KVHA VNP++ +RSG
Sbjct: 7 LMRAVRVFEFGGPEVLKLRSDIAVPIPK-DHQVLIKVHACGVNPVETYIRSG------TY 59
Query: 102 KRDPLHVKIKGEEFPLTLGRDVSGVVMECGLDVKYFKPGDEVWAAVPPWKQGTLSEFVVV 161
R PL P T G DV+GV+ G + FK GD V+ + G +E+ +
Sbjct: 60 SRKPL--------LPYTPGSDVAGVIEAVGDNASAFKKGDRVFTS--STISGGYAEYALA 109
Query: 162 SGNEVSHKPKSLTHTQAASLPYVALTAWSAINKVGGLNDKNCTGKRVLILGASGGVGTFA 221
+ + V P+ L Q A++ TA+ A+ + G+ VL+ GASGGVG A
Sbjct: 110 ADHTVYKLPEKLDFKQGAAIGIPYFTAYRALIHSACVK----AGESVLVHGASGGVGLAA 165
Query: 222 IQVMKAWDAHVTAVC-SQDASELVRKLGADDVIDYKSGSVEEQLKSL---KPFDFILDNV 277
Q+ +A+ + +++ ++V + GA +V +++ + +++K K D I++ +
Sbjct: 166 CQIARAYGLKILGTAGTEEGQKIVLQNGAHEVFNHREVNYIDKIKKYVGEKGIDIIIEML 225
Query: 278 GGSTETWAPDFLKKWSGATYVTLVTPFLLNMD-RLGIADGMLQTGVTVGSKALKHFWKGV 336
+ + D G + + + + ++ R +A GVT+ S + F
Sbjct: 226 --ANVNLSKDLSLLSHGGRVIVVGSRGTIEINPRDTMAKESSIIGVTLFSSTKEEF---- 279
Query: 337 HYRWAFFMASGPCLDDIAELVDAGKIRPVIEQTFPFSKVPEAFLKVERGH-ARGKTVI 393
++A + +G ++ G ++PVI +P KV EA + G A GK ++
Sbjct: 280 -QQYAAALQAG---------MEIGWLKPVIGSQYPLEKVAEAHENIIHGSGATGKMIL 327
>gi|194239676 crystallin, zeta isoform b [Homo sapiens]
Length = 295
Score = 88.6 bits (218), Expect = 9e-18
Identities = 89/354 (25%), Positives = 153/354 (43%), Gaps = 69/354 (19%)
Query: 42 VMPAWVIDKYGKNEVLRFTQNMMMPIIHYPNEVIVKVHAASVNPIDVNMRSGYGATALNM 101
+M A + ++G EVL+ ++ +PI ++V++KVHA VNP++ +RSG
Sbjct: 7 LMRAVRVFEFGGPEVLKLRSDIAVPIPK-DHQVLIKVHACGVNPVETYIRSG------TY 59
Query: 102 KRDPLHVKIKGEEFPLTLGRDVSGVVMECGLDVKYFKPGDEVWAAVPPWKQGTLSEFVVV 161
R PL P T G DV+GV+ G + FK GD V+ + G +E+ +
Sbjct: 60 SRKPL--------LPYTPGSDVAGVIEAVGDNASAFKKGDRVFTS--STISGGYAEYALA 109
Query: 162 SGNEVSHKPKSLTHTQAASLPYVALTAWSAINKVGGLNDKNCTGKRVLILGASGGVGTFA 221
+ + V P+ L Q A++ TA+ A+ + G+ VL+ GASGGVG A
Sbjct: 110 ADHTVYKLPEKLDFKQGAAIGIPYFTAYRALIHSACVK----AGESVLVHGASGGVGLAA 165
Query: 222 IQVMKAWDAHVTAVC-SQDASELVRKLGADDVIDYKSGSVEEQLKSLKPFDFILDNVGGS 280
Q+ +A+ + +++ ++V + GA +V +++ + +++K + G+
Sbjct: 166 CQIARAYGLKILGTAGTEEGQKIVLQNGAHEVFNHREVNYIDKIKVV--------GSRGT 217
Query: 281 TETWAPDFLKKWSGATYVTLVTPFLLNMDRLGIADGMLQTGVTVGSKALKHFWKGVHYRW 340
E D + K S VTL + + A LQ G+ +G W
Sbjct: 218 IEINPRDTMAKESSIIGVTLFSSTKEEFQQYAAA---LQAGMEIG-------W------- 260
Query: 341 AFFMASGPCLDDIAELVDAGKIRPVIEQTFPFSKVPEAFLKVERGH-ARGKTVI 393
++PVI +P KV EA + G A GK ++
Sbjct: 261 ---------------------LKPVIGSQYPLEKVAEAHENIIHGSGATGKMIL 293
>gi|28557745 zinc binding alcohol dehydrogenase domain containing 2
[Homo sapiens]
Length = 377
Score = 72.8 bits (177), Expect = 5e-13
Identities = 75/300 (25%), Positives = 129/300 (43%), Gaps = 32/300 (10%)
Query: 73 EVIVKVHAASVNPIDVNMRSGYGATALNMKRDPLHVKIKGEEFPLTLGRDVSGVVMECGL 132
+++V+ VN D+N +G + DP + P +G + G V+ GL
Sbjct: 64 DLLVRNRFVGVNASDINYSAG--------RYDP------SVKPPFDIGFEGIGEVVALGL 109
Query: 133 DVKYFKPGDEVWAAVPPWKQGTLSEFVVVSGNEVSHKPKSLTHTQAASLPYVALTAWSAI 192
+ A + P G+ +E+ VV + + P + +L TA+ ++
Sbjct: 110 SASARYTVGQAVAYMAP---GSFAEYTVVPASIATPVPS--VKPEYLTLLVSGTTAYISL 164
Query: 193 NKVGGLNDKNCTGKRVLILGASGGVGTFAIQVMKAWDAHVTAVCSQD-ASELVRKLGADD 251
++GGL++ GK+VL+ A+GG G FA+Q+ K HV CS D S ++ LG D
Sbjct: 165 KELGGLSE----GKKVLVTAAAGGTGQFAMQLSKKAKCHVIGTCSSDEKSAFLKSLGCDR 220
Query: 252 VIDYKSGSVEEQLKSLKP--FDFILDNVGGSTETWAPDFLKKWSGATYVTLVTPFLLNMD 309
I+YK+ V LK P D + ++VGG+ A D L + ++ +
Sbjct: 221 PINYKTEPVGTVLKQEYPEGVDVVYESVGGAMFDLAVDALATKGRLIVIGFISGYQTPTG 280
Query: 310 RLGIADGMLQTGVTVGSKALKHFWKGVHYRWAFFMASGPCLD-----DIAELVDAGKIRP 364
+ G L + S +++ F+ HY + A L+ D+ VD G + P
Sbjct: 281 LSPVKAGTLPAKLLKKSASVQGFFLN-HYLSKYQAAMSHLLEMCVSGDLVCEVDLGDLSP 339
>gi|18379349 vesicle amine transport protein 1 [Homo sapiens]
Length = 393
Score = 72.4 bits (176), Expect = 7e-13
Identities = 89/358 (24%), Positives = 153/358 (42%), Gaps = 35/358 (9%)
Query: 47 VIDKYGKNEVLRFTQNMMMPIIHYPNEVIVKVHAASVNPIDVNMRSGYGATALNMKRDPL 106
V+ +G + ++ P P ++ +++ A +N D+ R G L + PL
Sbjct: 52 VLTGFGGYDKVKLQSRPAAPPAPGPGQLTLRLRACGLNFADLMARQG-----LYDRLPPL 106
Query: 107 HVKIKGEEFPLTLGRDVSGVVMECGLDVKYFKPGDEVWAAVPPWKQGTLSEFVVVSGNEV 166
P+T G + +GVV+ G V K GD V + G E V V +
Sbjct: 107 ---------PVTPGMEGAGVVIAVGEGVSDRKAGDRVMVLN---RSGMWQEEVTVPSVQT 154
Query: 167 SHKPKSLTHTQAASLPYVALTAWSAINKVGGLNDKNCTGKRVLILGASGGVGTFAIQVMK 226
P+++T +AA+L +TA+ + G L G VL+ A+GGVG A+Q+ +
Sbjct: 155 FLIPEAMTFEEAAALLVNYITAYMVLFDFGNLQ----PGHSVLVHMAAGGVGMAAVQLCR 210
Query: 227 AWD-AHVTAVCSQDASELVRKLGADDVIDYKSGSVEEQLKSLKP--FDFILDNVGGSTET 283
+ V S E +++ G IDY + +++K + P D ++D +GGS
Sbjct: 211 TVENVTVFGTASASKHEALKENGVTHPIDYHTTDYVDEIKKISPKGVDIVMDPLGGSDTA 270
Query: 284 WAPDFLKKWSG-ATY--VTLVTPFLLNMDRLGIADGMLQTGVTV-----GSKALKHFWKG 335
+ LK TY L+T N+ L Q VT ++A+ F G
Sbjct: 271 KGYNLLKPMGKVVTYGMANLLTGPKRNLMALA-RTWWNQFSVTALQLLQANRAVCGFHLG 329
Query: 336 VHYRWAFFMASGPCLDDIAELVDAGKIRPVIEQTFPFSKVPEAFLKVERGHARGKTVI 393
+ + SG + + L + G I+P I+ +PF KV +A +++ GK ++
Sbjct: 330 -YLDGEVELVSG-VVARLLALYNQGHIKPHIDSVWPFEKVADAMKQMQEKKNVGKVLL 385
>gi|22538446 tumor protein p53 inducible protein 3 [Homo sapiens]
Length = 332
Score = 66.6 bits (161), Expect = 4e-11
Identities = 69/218 (31%), Positives = 101/218 (46%), Gaps = 36/218 (16%)
Query: 73 EVIVKVHAASVNPIDVNMRSGY-----GATALNMKRDPLHVKIKGEEFPLTLGRDVSGVV 127
EV++KV A+++N D+ R G GA+ + LG + SG V
Sbjct: 29 EVLLKVAASALNRADLMQRQGQYDPPPGASNI-------------------LGLEASGHV 69
Query: 128 MECGLDVK-YFKPGDEVWAAVPPWKQGTLSEFVVVSGNEVSHKPKSLTHTQAASLPYVAL 186
E G + ++K GD A +P G +++V V + P+ LT TQAA++P L
Sbjct: 70 AELGPGCQGHWKIGDTAMALLPG---GGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWL 126
Query: 187 TAWSAINKVGGLNDKNCTGKRVLILGASGGVGTFAIQVMK-AWDAHVTAVCSQDASELVR 245
TA+ ++ VG + G VLI GVGT AIQ+ + A + SQ ++
Sbjct: 127 TAFQLLHLVGNVQ----AGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAE 182
Query: 246 KLGADDVIDYKSGSVEE-QLKSLK--PFDFILDNVGGS 280
KLGA +YK E LK K + ILD +GGS
Sbjct: 183 KLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGS 220
>gi|22538444 tumor protein p53 inducible protein 3 [Homo sapiens]
Length = 332
Score = 66.6 bits (161), Expect = 4e-11
Identities = 69/218 (31%), Positives = 101/218 (46%), Gaps = 36/218 (16%)
Query: 73 EVIVKVHAASVNPIDVNMRSGY-----GATALNMKRDPLHVKIKGEEFPLTLGRDVSGVV 127
EV++KV A+++N D+ R G GA+ + LG + SG V
Sbjct: 29 EVLLKVAASALNRADLMQRQGQYDPPPGASNI-------------------LGLEASGHV 69
Query: 128 MECGLDVK-YFKPGDEVWAAVPPWKQGTLSEFVVVSGNEVSHKPKSLTHTQAASLPYVAL 186
E G + ++K GD A +P G +++V V + P+ LT TQAA++P L
Sbjct: 70 AELGPGCQGHWKIGDTAMALLPG---GGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWL 126
Query: 187 TAWSAINKVGGLNDKNCTGKRVLILGASGGVGTFAIQVMK-AWDAHVTAVCSQDASELVR 245
TA+ ++ VG + G VLI GVGT AIQ+ + A + SQ ++
Sbjct: 127 TAFQLLHLVGNVQ----AGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAE 182
Query: 246 KLGADDVIDYKSGSVEE-QLKSLK--PFDFILDNVGGS 280
KLGA +YK E LK K + ILD +GGS
Sbjct: 183 KLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGS 220
>gi|90669511 crystallin, zeta-like 1 [Homo sapiens]
Length = 349
Score = 65.9 bits (159), Expect = 6e-11
Identities = 49/157 (31%), Positives = 84/157 (53%), Gaps = 10/157 (6%)
Query: 108 VKIKGEEFPLTLGRDVSGVVMECGLDVKYFKPGDEVWAAVP-PWKQGTLSEFVVVSGNEV 166
+K+K + FP+ GR+++G+V++ G V +F+P DEV +P + L E V V + +
Sbjct: 53 MKMKKDLFPV--GREIAGIVLDVGSKVSFFQPDDEVVGILPLDSEDPGLCEVVRVHEHYL 110
Query: 167 SHKPKSLTHTQAASLPYVALTAWSAINKVGGLNDKNCTGKRVLILGASGGVGTFAIQVMK 226
HKP+ +T T+AA + A++A++ + L+ GK VLI+ + GT AIQ+
Sbjct: 111 VHKPEKVTWTEAAGSIRDGVRAYTALHYLSHLS----PGKSVLIMDGASAFGTIAIQLAH 166
Query: 227 AWDAHV-TAVCSQDASELVRKLGAD--DVIDYKSGSV 260
A V + CS + + + + VID +G V
Sbjct: 167 HRGAKVISTACSLEDKQCLERFRPPIARVIDVSNGKV 203
>gi|226059159 prostaglandin reductase 1 isoform 1 [Homo sapiens]
Length = 329
Score = 56.2 bits (134), Expect = 5e-08
Identities = 61/213 (28%), Positives = 97/213 (45%), Gaps = 17/213 (7%)
Query: 186 LTAWSAINKVGGLNDKNCTGKRVLILGASGGVGTFAIQVMKAWDAHVT-AVCSQDASELV 244
LTA+ + ++ G+ G+ V++ A+G VG+ Q+ K V AV S + +
Sbjct: 127 LTAYFGLLEICGVKG----GETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVAYL 182
Query: 245 RKLGADDVIDYKS-GSVEEQLKSLKP--FDFILDNVGGSTETWAPDFLKKWSGATYVTLV 301
+KLG D V +YK+ S+EE LK P +D DNVGG +KK+ +
Sbjct: 183 QKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAICGAI 242
Query: 302 TPFLLNMDRLG-IADGMLQTGVTVGSKALKHFWKGVHYRWAFFMASGPCLDDIAELVDAG 360
+ + +R G + G V ++ F V YRW A L D+ + V G
Sbjct: 243 STY----NRTGPLPPGPPPEIVIYQELRMEAF---VVYRWQGD-ARQKALKDLLKWVLEG 294
Query: 361 KIRPVIEQTFPFSKVPEAFLKVERGHARGKTVI 393
KI+ F +P AF+ + +G GKT++
Sbjct: 295 KIQYKEYIIEGFENMPAAFMGMLKGDNLGKTIV 327
>gi|226059133 prostaglandin reductase 1 isoform 1 [Homo sapiens]
Length = 329
Score = 56.2 bits (134), Expect = 5e-08
Identities = 61/213 (28%), Positives = 97/213 (45%), Gaps = 17/213 (7%)
Query: 186 LTAWSAINKVGGLNDKNCTGKRVLILGASGGVGTFAIQVMKAWDAHVT-AVCSQDASELV 244
LTA+ + ++ G+ G+ V++ A+G VG+ Q+ K V AV S + +
Sbjct: 127 LTAYFGLLEICGVKG----GETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVAYL 182
Query: 245 RKLGADDVIDYKS-GSVEEQLKSLKP--FDFILDNVGGSTETWAPDFLKKWSGATYVTLV 301
+KLG D V +YK+ S+EE LK P +D DNVGG +KK+ +
Sbjct: 183 QKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAICGAI 242
Query: 302 TPFLLNMDRLG-IADGMLQTGVTVGSKALKHFWKGVHYRWAFFMASGPCLDDIAELVDAG 360
+ + +R G + G V ++ F V YRW A L D+ + V G
Sbjct: 243 STY----NRTGPLPPGPPPEIVIYQELRMEAF---VVYRWQGD-ARQKALKDLLKWVLEG 294
Query: 361 KIRPVIEQTFPFSKVPEAFLKVERGHARGKTVI 393
KI+ F +P AF+ + +G GKT++
Sbjct: 295 KIQYKEYIIEGFENMPAAFMGMLKGDNLGKTIV 327
>gi|24308257 vesicle amine transport protein 1 homolog (T.
californica)-like [Homo sapiens]
Length = 419
Score = 54.3 bits (129), Expect = 2e-07
Identities = 92/372 (24%), Positives = 150/372 (40%), Gaps = 71/372 (19%)
Query: 52 GKNEVLRFTQNMMMPIIHYPNEVIVKVHAASVNPIDVNMRSGYGATALNMKRDPLHVKIK 111
G N++ F + M P E+ ++V A +N ID+ +R G N+ P
Sbjct: 52 GLNKLRLFRKAMPEP---QDGELKIRVKACGLNFIDLMVRQG------NIDNPP------ 96
Query: 112 GEEFPLTLGRDVSGVVMECGLDVKYFKPGDEVWAAVPPWKQGTLSEFVVVSGNEVSHKPK 171
+ PL G + SG+V G VK ++ GD V A V +E V V P
Sbjct: 97 --KTPLVPGFECSGIVEALGDSVKGYEIGDRVMAFV---NYNAWAEVVCTPVEFVYKIPD 151
Query: 172 SLTHTQAASLPYVALTAWSAINKVGGLNDKNCTGKRVLILGASGGVG------------- 218
++ ++AA+ P +TA+ + +V L + G VL+ A GGVG
Sbjct: 152 DMSFSEAAAFPMNFVTAYVMLFEVANLRE----GMSVLVHSAGGGVGQAVAQLCSTVPNV 207
Query: 219 -------TFAIQVMKAWDAHVTAVCSQDASELVR--KLGADDVIDYKSG-SVEEQLKSLK 268
TF + +K H+ + E+ R G D V+D G + + L LK
Sbjct: 208 TVFGTASTFKHEAIKDSVTHLFDRNADYVQEVKRISAEGVDIVLDCLCGDNTGKGLSLLK 267
Query: 269 PF-DFIL----DNVGGSTETWAPDFLKKWSGATYVTLVTPFLLNMDRLGIADGMLQTGVT 323
P +IL + V G T+++ F K W V V P L + IA L +
Sbjct: 268 PLGTYILYGSSNMVTGETKSFF-SFAKSW---WQVEKVNPIKLYEENKVIAGFSLLNLLF 323
Query: 324 VGSKALKHFWKGVHYRWAFFMASGPCLDDIAELVDAGKIRPVIEQTFPFSKVPEAFLKVE 383
+A +GV ++ + L + KI+PV++ + +V EA ++
Sbjct: 324 KQGRA--GLIRGV-------------VEKLIGLYNQKKIKPVVDSLWALEEVKEAMQRIH 368
Query: 384 RGHARGKTVINV 395
GK +++V
Sbjct: 369 DRGNIGKLILDV 380
>gi|156627571 sorbitol dehydrogenase [Homo sapiens]
Length = 357
Score = 47.8 bits (112), Expect = 2e-05
Identities = 54/220 (24%), Positives = 89/220 (40%), Gaps = 48/220 (21%)
Query: 71 PNEVIVKVHAASVNPIDVNMRSGYGATALNMKRDPLHVKIKGEEFPLTLGRDVSGVVMEC 130
PNEV++++H+ + DV+ YG + + P+ LG + SG V +
Sbjct: 32 PNEVLLRMHSVGICGSDVHYWE-YGRIGNFIVKKPM-----------VLGHEASGTVEKV 79
Query: 131 GLDVKYFKPGDEV--------------------------WAAVPPWKQGTLSEFVVVSGN 164
G VK+ KPGD V + A PP G L F +
Sbjct: 80 GSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPP-DDGNLCRFYKHNAA 138
Query: 165 EVSHKPKSLTHTQAASLPYVALTAWSAINKVGGLNDKNCTGKRVLILGASGGVGTFAIQV 224
P ++T + A + +++ + + GG+ G +VL+ GA G +G + V
Sbjct: 139 FCYKLPDNVTFEEGALIEPLSVGIHAC--RRGGVT----LGHKVLVCGA-GPIGMVTLLV 191
Query: 225 MKAWDAHVTAVCSQDASEL--VRKLGADDVIDYKSGSVEE 262
KA A V A+ L +++GAD V+ S +E
Sbjct: 192 AKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQE 231
>gi|226056130 prostaglandin reductase 1 isoform 2 [Homo sapiens]
Length = 301
Score = 47.4 bits (111), Expect = 2e-05
Identities = 37/111 (33%), Positives = 57/111 (51%), Gaps = 8/111 (7%)
Query: 186 LTAWSAINKVGGLNDKNCTGKRVLILGASGGVGTFAIQVMKAWDAHVT-AVCSQDASELV 244
LTA+ + ++ G+ G+ V++ A+G VG+ Q+ K V AV S + +
Sbjct: 127 LTAYFGLLEICGVKG----GETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVAYL 182
Query: 245 RKLGADDVIDYKS-GSVEEQLKSLKP--FDFILDNVGGSTETWAPDFLKKW 292
+KLG D V +YK+ S+EE LK P +D DNVGG +KK+
Sbjct: 183 QKLGFDVVFNYKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKF 233
>gi|67078404 trans-2-enoyl-CoA reductase, mitochondrial isoform a
[Homo sapiens]
Length = 373
Score = 46.6 bits (109), Expect = 4e-05
Identities = 62/238 (26%), Positives = 94/238 (39%), Gaps = 34/238 (14%)
Query: 72 NEVIVKVHAASVNPIDVNMRSG-YGATALNMKRDPLHVKIKGEEFPLTLGRDVSGVVMEC 130
++V VK+ AA +NP D+NM G YG E P G + V+
Sbjct: 71 SDVRVKMLAAPINPSDINMIQGNYGFL---------------PELPAVGGNEGVAQVVAV 115
Query: 131 GLDVKYFKPGDEVWAAVPPWKQGTLSEFVVVSGNEVSHKPKSLTHTQAASLPYVALTAWS 190
G +V KPGD W GT V S + P + AA+L TA+
Sbjct: 116 GSNVTGLKPGD--WVIPANAGLGTWRTEAVFSEEALIQVPSDIPLQSAATLGVNPCTAYR 173
Query: 191 AINKVGGLNDKNCTGKRVLILGASGGVGTFAIQVMKAWDAHVTAVCS-----QDASELVR 245
+ L G V+ ++ GVG IQ+ A V Q S+ ++
Sbjct: 174 MLMDFEQLQ----PGDSVIQNASNSGVGQAVIQIAAALGLRTINVVRDRPDIQKLSDRLK 229
Query: 246 KLGADDVI---DYKSGSVEEQLKSLKPFDFILDNVGGSTETWAPDFLKKWS-GATYVT 299
LGA+ VI + + ++ K + L+ VGG + T + L++ + G T VT
Sbjct: 230 SLGAEHVITEEELRRPEMKNFFKDMPQPRLALNCVGGKSST---ELLRQLARGGTMVT 284
>gi|197927207 crystallin, zeta isoform c [Homo sapiens]
Length = 192
Score = 43.9 bits (102), Expect = 3e-04
Identities = 45/195 (23%), Positives = 91/195 (46%), Gaps = 22/195 (11%)
Query: 205 GKRVLILGASGGVGTFAIQVMKAWDAHVTAVC-SQDASELVRKLGADDVIDYKSGSVEEQ 263
G+ VL+ GASGGVG A Q+ +A+ + +++ ++V + GA +V +++ + ++
Sbjct: 12 GESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQKIVLQNGAHEVFNHREVNYIDK 71
Query: 264 LKSL---KPFDFILDNVGGSTETWAPDFLKKWSGATYVTLVTPFLLNMD-RLGIADGMLQ 319
+K K D I++ + + + D G + + + + ++ R +A
Sbjct: 72 IKKYVGEKGIDIIIEML--ANVNLSKDLSLLSHGGRVIVVGSRGTIEINPRDTMAKESSI 129
Query: 320 TGVTVGSKALKHFWKGVHYRWAFFMASGPCLDDIAELVDAGKIRPVIEQTFPFSKVPEAF 379
GVT+ S + F ++A + +G ++ G ++PVI +P KV EA
Sbjct: 130 IGVTLFSSTKEEF-----QQYAAALQAG---------MEIGWLKPVIGSQYPLEKVAEAH 175
Query: 380 LKVERGH-ARGKTVI 393
+ G A GK ++
Sbjct: 176 ENIIHGSGATGKMIL 190
>gi|67078406 trans-2-enoyl-CoA reductase, mitochondrial isoform b
[Homo sapiens]
Length = 297
Score = 42.4 bits (98), Expect = 7e-04
Identities = 59/230 (25%), Positives = 88/230 (38%), Gaps = 34/230 (14%)
Query: 80 AASVNPIDVNMRSG-YGATALNMKRDPLHVKIKGEEFPLTLGRDVSGVVMECGLDVKYFK 138
AA +NP D+NM G YG E P G + V+ G +V K
Sbjct: 3 AAPINPSDINMIQGNYGFL---------------PELPAVGGNEGVAQVVAVGSNVTGLK 47
Query: 139 PGDEVWAAVPPWKQGTLSEFVVVSGNEVSHKPKSLTHTQAASLPYVALTAWSAINKVGGL 198
PGD W GT V S + P + AA+L TA+ + L
Sbjct: 48 PGD--WVIPANAGLGTWRTEAVFSEEALIQVPSDIPLQSAATLGVNPCTAYRMLMDFEQL 105
Query: 199 NDKNCTGKRVLILGASGGVGTFAIQVMKAWDAHVTAVCS-----QDASELVRKLGADDVI 253
G V+ ++ GVG IQ+ A V Q S+ ++ LGA+ VI
Sbjct: 106 Q----PGDSVIQNASNSGVGQAVIQIAAALGLRTINVVRDRPDIQKLSDRLKSLGAEHVI 161
Query: 254 ---DYKSGSVEEQLKSLKPFDFILDNVGGSTETWAPDFLKKWS-GATYVT 299
+ + ++ K + L+ VGG + T + L++ + G T VT
Sbjct: 162 TEEELRRPEMKNFFKDMPQPRLALNCVGGKSST---ELLRQLARGGTMVT 208
>gi|226246682 prostaglandin reductase 2 [Homo sapiens]
Length = 351
Score = 40.4 bits (93), Expect = 0.003
Identities = 38/150 (25%), Positives = 65/150 (43%), Gaps = 16/150 (10%)
Query: 140 GDEVWAAVPPWKQGTLSEFVVVSGNEVSHKPKSLTHTQAASLPYVALTAWSAINKVGGLN 199
GD V + PW+ V++ GN + L + ++ + + G+
Sbjct: 93 GDFVTSFYWPWQTK-----VILDGNSLEKVDPQLVDGHLSY--FLGAIGMPGLTSLIGIQ 145
Query: 200 DKNC----TGKRVLILGASGGVGTFAIQVMKAWD-AHVTAVCS--QDASELVRKLGADDV 252
+K + K +++ GA+G G+ A Q+ + V +C + L +LG D
Sbjct: 146 EKGHITAGSNKTMVVSGAAGACGSVAGQIGHFLGCSRVVGICGTHEKCILLTSELGFDAA 205
Query: 253 IDYKSGSVEEQLKSLKP--FDFILDNVGGS 280
I+YK +V EQL+ P D DNVGG+
Sbjct: 206 INYKKDNVAEQLRESCPAGVDVYFDNVGGN 235
>gi|226246680 prostaglandin reductase 2 [Homo sapiens]
Length = 351
Score = 40.4 bits (93), Expect = 0.003
Identities = 38/150 (25%), Positives = 65/150 (43%), Gaps = 16/150 (10%)
Query: 140 GDEVWAAVPPWKQGTLSEFVVVSGNEVSHKPKSLTHTQAASLPYVALTAWSAINKVGGLN 199
GD V + PW+ V++ GN + L + ++ + + G+
Sbjct: 93 GDFVTSFYWPWQTK-----VILDGNSLEKVDPQLVDGHLSY--FLGAIGMPGLTSLIGIQ 145
Query: 200 DKNC----TGKRVLILGASGGVGTFAIQVMKAWD-AHVTAVCS--QDASELVRKLGADDV 252
+K + K +++ GA+G G+ A Q+ + V +C + L +LG D
Sbjct: 146 EKGHITAGSNKTMVVSGAAGACGSVAGQIGHFLGCSRVVGICGTHEKCILLTSELGFDAA 205
Query: 253 IDYKSGSVEEQLKSLKP--FDFILDNVGGS 280
I+YK +V EQL+ P D DNVGG+
Sbjct: 206 INYKKDNVAEQLRESCPAGVDVYFDNVGGN 235
>gi|22748929 prostaglandin reductase 2 [Homo sapiens]
Length = 351
Score = 40.4 bits (93), Expect = 0.003
Identities = 38/150 (25%), Positives = 65/150 (43%), Gaps = 16/150 (10%)
Query: 140 GDEVWAAVPPWKQGTLSEFVVVSGNEVSHKPKSLTHTQAASLPYVALTAWSAINKVGGLN 199
GD V + PW+ V++ GN + L + ++ + + G+
Sbjct: 93 GDFVTSFYWPWQTK-----VILDGNSLEKVDPQLVDGHLSY--FLGAIGMPGLTSLIGIQ 145
Query: 200 DKNC----TGKRVLILGASGGVGTFAIQVMKAWD-AHVTAVCS--QDASELVRKLGADDV 252
+K + K +++ GA+G G+ A Q+ + V +C + L +LG D
Sbjct: 146 EKGHITAGSNKTMVVSGAAGACGSVAGQIGHFLGCSRVVGICGTHEKCILLTSELGFDAA 205
Query: 253 IDYKSGSVEEQLKSLKP--FDFILDNVGGS 280
I+YK +V EQL+ P D DNVGG+
Sbjct: 206 INYKKDNVAEQLRESCPAGVDVYFDNVGGN 235
>gi|71565152 class II alcohol dehydrogenase, pi subunit [Homo
sapiens]
Length = 380
Score = 38.1 bits (87), Expect = 0.014
Identities = 78/338 (23%), Positives = 120/338 (35%), Gaps = 84/338 (24%)
Query: 109 KIKGEEFPLTLGRDVSGVVMECGLDVKYFKPGDEVWAAVPPWKQ-------------GTL 155
K +G FP+ +G + +G+V G V KPGD+V P + G +
Sbjct: 57 KFEGLAFPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKI 116
Query: 156 SEFVVVSGNEVSHKPKSLTHTQAASLPY--VALTAWSAINKVGGLN----DKNCTGKRVL 209
S + ++ + K+ T Y + +S V +N D + +RV
Sbjct: 117 SNLKSPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVC 176
Query: 210 ILGAS-------------------------GGVGTFAIQVMKAWDAHVTAVCSQDASELV 244
+LG GGVG A+ KA A ++ + V
Sbjct: 177 LLGCGFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFV 236
Query: 245 --RKLGADDVIDYKS--GSVEEQLKSLKP--FDFILDNVGGS-TETWAPDFLKK-WSGAT 296
+ LGA D ++ + ++E + L DF LD GGS T A D W T
Sbjct: 237 KAKALGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCT 296
Query: 297 YVTLVTPFLLNMDRLGIADGMLQTGVTVGSKALKHFWK----GVHYRWAFFMASGPCLDD 352
++ GV GSK L F + G FF +D
Sbjct: 297 FI----------------------GVAAGSKGLTIFPEELIIGRTINGTFF-GGWKSVDS 333
Query: 353 IAELVDAGK-----IRPVIEQTFPFSKVPEAFLKVERG 385
I +LV K + ++ T PF K+ EAF + +G
Sbjct: 334 IPKLVTDYKNKKFNLDALVTHTLPFDKISEAFDLMNQG 371
>gi|7705925 dicarbonyl/L-xylulose reductase [Homo sapiens]
Length = 244
Score = 37.7 bits (86), Expect = 0.018
Identities = 25/77 (32%), Positives = 38/77 (49%), Gaps = 5/77 (6%)
Query: 205 GKRVLILGASGGVGTFAIQVMKAWDAHVTAV--CSQDASELVRKLGADDVIDYKSG---S 259
G+RVL+ GA G+G +Q + A A V AV D LVR+ + + G +
Sbjct: 7 GRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEPVCVDLGDWEA 66
Query: 260 VEEQLKSLKPFDFILDN 276
E L S+ P D +++N
Sbjct: 67 TERALGSVGPVDLLVNN 83
>gi|41872631 fatty acid synthase [Homo sapiens]
Length = 2511
Score = 32.7 bits (73), Expect = 0.59
Identities = 42/154 (27%), Positives = 65/154 (42%), Gaps = 25/154 (16%)
Query: 71 PNEVIVKVHAASVNPIDVNMRSGYGATALNMKRDPLHVKIKGEEFPLTLGRDVSGVVMEC 130
P + V+ AS+N D+ + +G + + + G EF GRD SG
Sbjct: 1559 PGAQLCTVYYASLNFRDIMLATGKLSPDAIPGKWTSQDSLLGMEFS---GRDASG----- 1610
Query: 131 GLDVKYFKPGDEVWAAVPPWKQGTLSEFVVVSGNEVSHKPKSLTHTQAASLPYVALTAWS 190
V VP L+ V++S + + P + T +AAS+P V TA+
Sbjct: 1611 ----------KRVMGLVPA---KGLATSVLLSPDFLWDVPSNWTLEEAASVPVVYSTAYY 1657
Query: 191 AINKVGGLNDKNCTGKRVLILGASGGVGTFAIQV 224
A+ G + G+ +LI SGGVG AI +
Sbjct: 1658 ALVVRGRVR----PGETLLIHSGSGGVGQAAIAI 1687
>gi|4501933 class I alcohol dehydrogenase, gamma subunit [Homo
sapiens]
Length = 375
Score = 32.0 bits (71), Expect = 1.0
Identities = 89/363 (24%), Positives = 132/363 (36%), Gaps = 92/363 (25%)
Query: 72 NEVIVKVHAASVNPIDVNMRSGYGATALNMKRDPLHVKIKGEEFPLTLGRDVSGVVMECG 131
+EV +K+ AA + D ++ SG T L P+ LG + +G+V G
Sbjct: 35 HEVRIKMVAAGICRSDEHVVSGNLVTPL----------------PVILGHEAAGIVESVG 78
Query: 132 LDVKYFKPGDEVWAAVPPW----------------------KQGTLSEFV---VVSGNEV 166
V KPGD+V P +GTL + SG +
Sbjct: 79 EGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPI 138
Query: 167 SHKPKSLTHTQ--------------AASLPYVAL------TAWSAINKVGGLNDKNCTGK 206
H T +Q A+ L V L T + + KV K G
Sbjct: 139 HHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVA----KVTPGS 194
Query: 207 RVLILGASGGVGTFAIQVMK-AWDAHVTAV-CSQDASELVRKLGADDVI---DYKSGSVE 261
+ G GGVG + K A A + AV ++D ++LGA + I DYK ++
Sbjct: 195 TCAVFGL-GGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKK-PIQ 252
Query: 262 EQLKSLKP--FDFILDNVGGSTETWAPDFL--KKWSGATYVTLVTPFLLNMDRLGIADGM 317
E LK + DF + V G +T L + G + + V P + L I +
Sbjct: 253 EVLKEMTDGGVDFSFE-VIGRLDTMMASLLCCHEACGTSVIVGVPP---DSQNLSINPML 308
Query: 318 LQTGVTVGSKALKHFWKGVHYRWAFFMASGPCLDDIAE-LVDAGKIRPVIEQTFPFSKVP 376
L TG T WKG + S P L +A+ + + +I PF K+
Sbjct: 309 LLTGRT---------WKGAIFGGFKSKESVPKL--VADFMAKKFSLDALITNILPFEKIN 357
Query: 377 EAF 379
E F
Sbjct: 358 EGF 360
>gi|71743840 class IV alcohol dehydrogenase, mu or sigma subunit
[Homo sapiens]
Length = 386
Score = 30.0 bits (66), Expect = 3.8
Identities = 15/37 (40%), Positives = 22/37 (59%), Gaps = 3/37 (8%)
Query: 110 IKG---EEFPLTLGRDVSGVVMECGLDVKYFKPGDEV 143
IKG +FP+ +G + +G+V G V KPGD+V
Sbjct: 66 IKGTMVSKFPVIVGHEATGIVESIGEGVTTVKPGDKV 102
>gi|222136615 exonuclease NEF-sp isoform 2 [Homo sapiens]
Length = 743
Score = 29.6 bits (65), Expect = 5.0
Identities = 22/82 (26%), Positives = 31/82 (37%), Gaps = 8/82 (9%)
Query: 150 WKQGTLSEFVVVSGNEVSHKPKSLTHTQAASLPYVALTAWSAINKVGGLNDKNCTGKRVL 209
W +G E + G V P Q L + + AW K+G L + C G L
Sbjct: 650 WLRGLPPESTRLPGLRVVPPPFEQEALQTLKLDHPKIAAWRWSRKIGKLYNSLCPGTLCL 709
Query: 210 IL--------GASGGVGTFAIQ 223
IL G+ G+G I+
Sbjct: 710 ILLPGTKSTHGSLSGLGLMGIK 731
>gi|222136613 exonuclease NEF-sp isoform 1 [Homo sapiens]
Length = 774
Score = 29.6 bits (65), Expect = 5.0
Identities = 22/82 (26%), Positives = 31/82 (37%), Gaps = 8/82 (9%)
Query: 150 WKQGTLSEFVVVSGNEVSHKPKSLTHTQAASLPYVALTAWSAINKVGGLNDKNCTGKRVL 209
W +G E + G V P Q L + + AW K+G L + C G L
Sbjct: 681 WLRGLPPESTRLPGLRVVPPPFEQEALQTLKLDHPKIAAWRWSRKIGKLYNSLCPGTLCL 740
Query: 210 IL--------GASGGVGTFAIQ 223
IL G+ G+G I+
Sbjct: 741 ILLPGTKSTHGSLSGLGLMGIK 762
>gi|189011544 ubiquitously transcribed tetratricopeptide repeat, X
chromosome [Homo sapiens]
Length = 1401
Score = 29.3 bits (64), Expect = 6.5
Identities = 20/70 (28%), Positives = 30/70 (42%), Gaps = 6/70 (8%)
Query: 89 NMRSGYGATALNMKRDPLHVKIKGEEFPLTLGRDVSGVVMECGLDVKYFKPGDEVWAAVP 148
N+ S G T L M L++K+ G P G + +++ PGD W VP
Sbjct: 1117 NLLSHVGHTILGMNTVQLYMKVPGSRTP---GHQENNNFCSVNINIG---PGDCEWFVVP 1170
Query: 149 PWKQGTLSEF 158
G L++F
Sbjct: 1171 EGYWGVLNDF 1180
>gi|7706523 WW domain-containing oxidoreductase isoform 1 [Homo
sapiens]
Length = 414
Score = 29.3 bits (64), Expect = 6.5
Identities = 17/52 (32%), Positives = 26/52 (50%), Gaps = 2/52 (3%)
Query: 198 LNDKNCTGKRVLILGASGGVGTFAIQVMKAWDAHVTAVCSQ--DASELVRKL 247
L ++ TGK V++ GA+ G+G + AHV C ASE V ++
Sbjct: 117 LQGRDFTGKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVSRI 168
>gi|18860884 WW domain-containing oxidoreductase isoform 2 [Homo
sapiens]
Length = 189
Score = 29.3 bits (64), Expect = 6.5
Identities = 17/52 (32%), Positives = 26/52 (50%), Gaps = 2/52 (3%)
Query: 198 LNDKNCTGKRVLILGASGGVGTFAIQVMKAWDAHVTAVCSQ--DASELVRKL 247
L ++ TGK V++ GA+ G+G + AHV C ASE V ++
Sbjct: 117 LQGRDFTGKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVSRI 168
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.418
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,587,813
Number of Sequences: 37866
Number of extensions: 601030
Number of successful extensions: 1095
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 1055
Number of HSP's gapped (non-prelim): 40
length of query: 396
length of database: 18,247,518
effective HSP length: 104
effective length of query: 292
effective length of database: 14,309,454
effective search space: 4178360568
effective search space used: 4178360568
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.