Guide to the Human Genome
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Name: TYK2 Sequence: fasta or formatted (1187aa) NCBI GI: 187608615
Description:

tyrosine kinase 2

Referenced in:

Protein Tyrosine Phosphatases
Non-Receptor Tyrosine Kinase Pathways

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.9         82           3
 C cysteine            2.7         32           2
 D aspartate           4.5         54           2
 E glutamate           7.2         85           3
 F phenylalanine       4.0         47           1
 G glycine             7.6         90           3
 H histidine           4.3         51           2
 I isoleucine          3.5         42           2
 K lysine              3.8         45           2
 L leucine            11.6        138           3
 M methionine          2.0         24           1
 N asparagine          2.2         26           1
 P proline             6.9         82           2
 Q glutamine           4.4         52           2
 R arginine            7.2         86           2
 S serine              6.4         76           2
 T threonine           4.0         48           1
 V valine              6.1         73           2
 W tryptophan          1.6         19           2
 Y tyrosine            2.9         35           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   tyrosine kinase 2 
JAK1                  0.397   janus kinase 1 
JAK2                  0.300   Janus kinase 2 
JAK3                  0.283   Janus kinase 3 
TNK2                  0.061   tyrosine kinase, non-receptor, 2 isoform 1 
TNK2                  0.061   tyrosine kinase, non-receptor, 2 isoform 2 
NTRK3                 0.059   neurotrophic tyrosine kinase, receptor, type 3 isofo...
ERBB4                 0.059   v-erb-a erythroblastic leukemia viral oncogene homo...
ERBB4                 0.059   v-erb-a erythroblastic leukemia viral oncogene homolo...
NTRK2                 0.058   neurotrophic tyrosine kinase, receptor, type 2 isofo...
NTRK2                 0.058   neurotrophic tyrosine kinase, receptor, type 2 isofo...
PTK2B                 0.058   PTK2B protein tyrosine kinase 2 beta isoform a [Homo...
PTK2B                 0.058   PTK2B protein tyrosine kinase 2 beta isoform b [Homo...
PTK2B                 0.058   PTK2B protein tyrosine kinase 2 beta isoform a [Homo...
PTK2B                 0.058   PTK2B protein tyrosine kinase 2 beta isoform a [Homo...
NTRK1                 0.057   neurotrophic tyrosine kinase, receptor, type 1 isofo...
NTRK1                 0.057   neurotrophic tyrosine kinase, receptor, type 1 isofor...
NTRK1                 0.057   neurotrophic tyrosine kinase, receptor, type 1 isofo...
NTRK3                 0.056   neurotrophic tyrosine kinase, receptor, type 3 isofo...
FGFR4                 0.056   fibroblast growth factor receptor 4 isoform 2 precur...
FGFR4                 0.056   fibroblast growth factor receptor 4 isoform 1 precur...
FGFR4                 0.056   fibroblast growth factor receptor 4 isoform 1 precur...
PTK2                  0.056   PTK2 protein tyrosine kinase 2 isoform b 
PTK2                  0.056   PTK2 protein tyrosine kinase 2 isoform a 
LYN                   0.056   Yamaguchi sarcoma viral (v-yes-1) oncogene homolog ...
LYN                   0.056   Yamaguchi sarcoma viral (v-yes-1) oncogene homolog is...
SYK                   0.055   spleen tyrosine kinase isoform 2 
SYK                   0.055   spleen tyrosine kinase isoform 1 
MATK                  0.055   megakaryocyte-associated tyrosine kinase isoform c [...
MATK                  0.055   megakaryocyte-associated tyrosine kinase isoform b [...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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