Guide to the Human Genome
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Search of human proteins with 46409442

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|46409442 hypothetical protein LOC389197 [Homo sapiens]
         (276 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|46409442 hypothetical protein LOC389197 [Homo sapiens]             543   e-155
gi|154277118 spectrin repeat containing, nuclear envelope 1 isof...    39   0.006
gi|23097308 spectrin repeat containing, nuclear envelope 1 isofo...    39   0.006
gi|154277116 spectrin repeat containing, nuclear envelope 1 isof...    39   0.006
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]         39   0.006
gi|41322923 plectin 1 isoform 11 [Homo sapiens]                        37   0.014
gi|41322914 plectin 1 isoform 10 [Homo sapiens]                        37   0.014
gi|41322919 plectin 1 isoform 8 [Homo sapiens]                         37   0.014
gi|41322910 plectin 1 isoform 7 [Homo sapiens]                         37   0.014
gi|41322916 plectin 1 isoform 6 [Homo sapiens]                         37   0.014
gi|41322908 plectin 1 isoform 3 [Homo sapiens]                         37   0.014
gi|41322912 plectin 1 isoform 2 [Homo sapiens]                         37   0.014
gi|47607492 plectin 1 isoform 1 [Homo sapiens]                         37   0.014
gi|169204908 PREDICTED: similar to Thyroid hormone receptor inte...    36   0.032
gi|169205597 PREDICTED: similar to Thyroid hormone receptor inte...    36   0.032
gi|169203883 PREDICTED: hypothetical protein [Homo sapiens]            36   0.032
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]                36   0.032
gi|217330634 serine/threonine kinase 36 [Homo sapiens]                 35   0.055
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]    35   0.071
gi|45446749 kinesin family member 5A [Homo sapiens]                    35   0.071
gi|22035604 mitogen-activated protein kinase kinase kinase kinas...    35   0.071
gi|149363664 septin 8 isoform d [Homo sapiens]                         35   0.071
gi|149363638 septin 8 isoform c [Homo sapiens]                         35   0.071
gi|149363689 septin 8 isoform a [Homo sapiens]                         35   0.071
gi|149363661 septin 8 isoform b [Homo sapiens]                         35   0.071
gi|24308303 SH3-binding domain protein 5-like [Homo sapiens]           35   0.071
gi|239787092 A20-binding inhibitor of NF-kappaB activation 2 iso...    34   0.12 
gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]    34   0.12 
gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]    34   0.12 
gi|32698688 citron [Homo sapiens]                                      34   0.12 

>gi|46409442 hypothetical protein LOC389197 [Homo sapiens]
          Length = 276

 Score =  543 bits (1398), Expect = e-155
 Identities = 276/276 (100%), Positives = 276/276 (100%)

Query: 1   MLRDSEAEVTEEDPRLRAQQLHHRVLTLQCQLRDQGAAHQASLDEATRLQEELQAKLEEL 60
           MLRDSEAEVTEEDPRLRAQQLHHRVLTLQCQLRDQGAAHQASLDEATRLQEELQAKLEEL
Sbjct: 1   MLRDSEAEVTEEDPRLRAQQLHHRVLTLQCQLRDQGAAHQASLDEATRLQEELQAKLEEL 60

Query: 61  QKKQHEAKLAVTPLKAKIASLVRKCRERNRLITHLLQELHRHGLGNLLLSELAQNMLNDV 120
           QKKQHEAKLAVTPLKAKIASLVRKCRERNRLITHLLQELHRHGLGNLLLSELAQNMLNDV
Sbjct: 61  QKKQHEAKLAVTPLKAKIASLVRKCRERNRLITHLLQELHRHGLGNLLLSELAQNMLNDV 120

Query: 121 ALAEYTATFLAPGVPETSHHLDVKSEMTAALRAQTYLLNPEMDSVLQSSLSSESWPIPEP 180
           ALAEYTATFLAPGVPETSHHLDVKSEMTAALRAQTYLLNPEMDSVLQSSLSSESWPIPEP
Sbjct: 121 ALAEYTATFLAPGVPETSHHLDVKSEMTAALRAQTYLLNPEMDSVLQSSLSSESWPIPEP 180

Query: 181 EWPAQTAQLDSLKLPLSLVSTLDPGTCLAAVTVEPGLPAQRLQEKGGMPCPALQVDNVPA 240
           EWPAQTAQLDSLKLPLSLVSTLDPGTCLAAVTVEPGLPAQRLQEKGGMPCPALQVDNVPA
Sbjct: 181 EWPAQTAQLDSLKLPLSLVSTLDPGTCLAAVTVEPGLPAQRLQEKGGMPCPALQVDNVPA 240

Query: 241 PSELLSPARILAFHQELRQSICSNSQVHKSPLELEM 276
           PSELLSPARILAFHQELRQSICSNSQVHKSPLELEM
Sbjct: 241 PSELLSPARILAFHQELRQSICSNSQVHKSPLELEM 276


>gi|154277118 spectrin repeat containing, nuclear envelope 1 isoform
           4 [Homo sapiens]
          Length = 3321

 Score = 38.5 bits (88), Expect = 0.006
 Identities = 53/210 (25%), Positives = 86/210 (40%), Gaps = 42/210 (20%)

Query: 31  QLRDQGAAHQASLDEATRLQEELQAKLEELQKKQHEAKLAVTPLKAKIASLVRKCRERNR 90
           QLR+Q   HQ  L+E+  +  EL+A  E+LQ     +      +  ++A L R+  E  +
Sbjct: 85  QLREQYILHQTLLEESKEIDSELEAMTEKLQ--YLTSVYCTEKMSQQVAELGRETEELRQ 142

Query: 91  LITHLLQELHRHGLGNLLLSELAQNMLNDVALAEYTATFLAPGVPETSHHLDVKSEMTAA 150
           +I   LQ L              Q+   D+   E                 ++K    A 
Sbjct: 143 MIKIRLQNL--------------QDAAKDMKKFE----------------AELKKLQAAL 172

Query: 151 LRAQTYLLNPEMDSV-LQSSLSSESWPIPEPEW---PAQTAQL--DSLKLPLSLVSTLDP 204
            +AQ  L +PE+  + L+  LS     + E E      Q  QL   +L++P  +V++L  
Sbjct: 173 EQAQATLTSPEVGRLSLKEQLSHRQHLLSEMESLKPKVQAVQLCQSALRIPEDVVASLP- 231

Query: 205 GTCLAAVTVEPGLPAQRLQEKGGMPCPALQ 234
             C AA+ ++    A RLQ      C  +Q
Sbjct: 232 -LCHAALRLQE--EASRLQHTAIQQCNIMQ 258



 Score = 29.6 bits (65), Expect = 3.0
 Identities = 22/75 (29%), Positives = 36/75 (48%), Gaps = 7/75 (9%)

Query: 32   LRDQG-------AAHQASLDEATRLQEELQAKLEELQKKQHEAKLAVTPLKAKIASLVRK 84
            LR QG       A  Q  L   +  +  LQA+L E+Q+K   A + +   K K+A L++ 
Sbjct: 2139 LRQQGSYILTVEAGKQLLLSADSGAEAALQAELAEIQEKWKSASMRLEEQKKKLAFLLKD 2198

Query: 85   CRERNRLITHLLQEL 99
              +  + I   L++L
Sbjct: 2199 WEKCEKGIADSLEKL 2213


>gi|23097308 spectrin repeat containing, nuclear envelope 1 isoform 2
            [Homo sapiens]
          Length = 8749

 Score = 38.5 bits (88), Expect = 0.006
 Identities = 53/210 (25%), Positives = 86/210 (40%), Gaps = 42/210 (20%)

Query: 31   QLRDQGAAHQASLDEATRLQEELQAKLEELQKKQHEAKLAVTPLKAKIASLVRKCRERNR 90
            QLR+Q   HQ  L+E+  +  EL+A  E+LQ     +      +  ++A L R+  E  +
Sbjct: 5490 QLREQYILHQTLLEESKEIDSELEAMTEKLQ--YLTSVYCTEKMSQQVAELGRETEELRQ 5547

Query: 91   LITHLLQELHRHGLGNLLLSELAQNMLNDVALAEYTATFLAPGVPETSHHLDVKSEMTAA 150
            +I   LQ L              Q+   D+   E                 ++K    A 
Sbjct: 5548 MIKIRLQNL--------------QDAAKDMKKFE----------------AELKKLQAAL 5577

Query: 151  LRAQTYLLNPEMDSV-LQSSLSSESWPIPEPEW---PAQTAQL--DSLKLPLSLVSTLDP 204
             +AQ  L +PE+  + L+  LS     + E E      Q  QL   +L++P  +V++L  
Sbjct: 5578 EQAQATLTSPEVGRLSLKEQLSHRQHLLSEMESLKPKVQAVQLCQSALRIPEDVVASLP- 5636

Query: 205  GTCLAAVTVEPGLPAQRLQEKGGMPCPALQ 234
              C AA+ ++    A RLQ      C  +Q
Sbjct: 5637 -LCHAALRLQE--EASRLQHTAIQQCNIMQ 5663



 Score = 29.6 bits (65), Expect = 3.0
 Identities = 22/75 (29%), Positives = 36/75 (48%), Gaps = 7/75 (9%)

Query: 32   LRDQG-------AAHQASLDEATRLQEELQAKLEELQKKQHEAKLAVTPLKAKIASLVRK 84
            LR QG       A  Q  L   +  +  LQA+L E+Q+K   A + +   K K+A L++ 
Sbjct: 7544 LRQQGSYILTVEAGKQLLLSADSGAEAALQAELAEIQEKWKSASMRLEEQKKKLAFLLKD 7603

Query: 85   CRERNRLITHLLQEL 99
              +  + I   L++L
Sbjct: 7604 WEKCEKGIADSLEKL 7618


>gi|154277116 spectrin repeat containing, nuclear envelope 1 isoform 1
            [Homo sapiens]
          Length = 8797

 Score = 38.5 bits (88), Expect = 0.006
 Identities = 53/210 (25%), Positives = 86/210 (40%), Gaps = 42/210 (20%)

Query: 31   QLRDQGAAHQASLDEATRLQEELQAKLEELQKKQHEAKLAVTPLKAKIASLVRKCRERNR 90
            QLR+Q   HQ  L+E+  +  EL+A  E+LQ     +      +  ++A L R+  E  +
Sbjct: 5561 QLREQYILHQTLLEESKEIDSELEAMTEKLQ--YLTSVYCTEKMSQQVAELGRETEELRQ 5618

Query: 91   LITHLLQELHRHGLGNLLLSELAQNMLNDVALAEYTATFLAPGVPETSHHLDVKSEMTAA 150
            +I   LQ L              Q+   D+   E                 ++K    A 
Sbjct: 5619 MIKIRLQNL--------------QDAAKDMKKFE----------------AELKKLQAAL 5648

Query: 151  LRAQTYLLNPEMDSV-LQSSLSSESWPIPEPEW---PAQTAQL--DSLKLPLSLVSTLDP 204
             +AQ  L +PE+  + L+  LS     + E E      Q  QL   +L++P  +V++L  
Sbjct: 5649 EQAQATLTSPEVGRLSLKEQLSHRQHLLSEMESLKPKVQAVQLCQSALRIPEDVVASLP- 5707

Query: 205  GTCLAAVTVEPGLPAQRLQEKGGMPCPALQ 234
              C AA+ ++    A RLQ      C  +Q
Sbjct: 5708 -LCHAALRLQE--EASRLQHTAIQQCNIMQ 5734



 Score = 29.6 bits (65), Expect = 3.0
 Identities = 22/75 (29%), Positives = 36/75 (48%), Gaps = 7/75 (9%)

Query: 32   LRDQG-------AAHQASLDEATRLQEELQAKLEELQKKQHEAKLAVTPLKAKIASLVRK 84
            LR QG       A  Q  L   +  +  LQA+L E+Q+K   A + +   K K+A L++ 
Sbjct: 7615 LRQQGSYILTVEAGKQLLLSADSGAEAALQAELAEIQEKWKSASMRLEEQKKKLAFLLKD 7674

Query: 85   CRERNRLITHLLQEL 99
              +  + I   L++L
Sbjct: 7675 WEKCEKGIADSLEKL 7689


>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
          Length = 2115

 Score = 38.5 bits (88), Expect = 0.006
 Identities = 27/98 (27%), Positives = 52/98 (53%), Gaps = 8/98 (8%)

Query: 2   LRDSEAEVTEEDPRLRAQQLHHRVLTLQCQLRDQGA-AHQASLDEATRLQEELQAKLEEL 60
           LR+ +A + + +   + +     +L  Q Q+ ++   + Q S+ +A R + EL  K+EEL
Sbjct: 596 LRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEEL 655

Query: 61  Q-------KKQHEAKLAVTPLKAKIASLVRKCRERNRL 91
           Q       ++QHEA+  V  L+ ++ S  +K  E+ R+
Sbjct: 656 QACVETARQEQHEAQAQVAELELQLRSEQQKATEKERV 693



 Score = 30.0 bits (66), Expect = 2.3
 Identities = 26/96 (27%), Positives = 44/96 (45%), Gaps = 15/96 (15%)

Query: 18   AQQLHHRVLTLQCQL--RDQGAAH------------QASLDEATRLQEELQAKLEELQKK 63
            AQ+L  ++  LQ QL  ++Q A H             A   +   LQE+L++ LE+LQK+
Sbjct: 1586 AQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRS-LEQLQKE 1644

Query: 64   QHEAKLAVTPLKAKIASLVRKCRERNRLITHLLQEL 99
              E +     L  ++     K +E  +   HL  ++
Sbjct: 1645 NKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQV 1680



 Score = 28.9 bits (63), Expect = 5.1
 Identities = 45/173 (26%), Positives = 73/173 (42%), Gaps = 24/173 (13%)

Query: 2   LRDSEAEVTEEDPRLRAQQLHHRVLTLQCQLRDQGAAHQASLDEATRLQEELQAKLEELQ 61
           L ++   +TE+D ++   Q     L L   L ++ AA      E     EEL+ K E L 
Sbjct: 237 LAENRKLLTEKDAQIAMMQQRIDRLAL---LNEKQAASPLEPKEL----EELRDKNESLT 289

Query: 62  KKQHEAKLAVTPLKAKIASLVRKCR---ERNRLITHLLQELHRHGLGNLLLSELAQNMLN 118
            + HE       LK + + + RK     E N  ++  L+E   H      L +L Q+ LN
Sbjct: 290 MRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASH------LQQL-QDALN 342

Query: 119 DVALAEYTATFLAPGVPETSHHLDVKSEMTAALRAQTYLLNPEMDSVLQSSLS 171
           ++      AT              ++ E++AAL+ +  L   E + +LQ  LS
Sbjct: 343 ELTEEHSKAT-----QEWLEKQAQLEKELSAALQDKKCL--EEKNEILQGKLS 388



 Score = 28.1 bits (61), Expect = 8.7
 Identities = 46/198 (23%), Positives = 86/198 (43%), Gaps = 19/198 (9%)

Query: 38   AHQASLDEATRLQEELQAKLEELQKKQHEAKLAVTPLK---AKIASLVRKCRERNRLITH 94
            A QA   E+ +  + LQA+L ELQ +  + + A    K    K  +     +++N+ +  
Sbjct: 1574 AVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQE 1633

Query: 95   LLQELHRHGLGNLLLSELAQNMLNDVALAEYTATFLAPGVPETSHHLDVKSEMTAALRAQ 154
             L+ L +    N  L   A+ + +++      A        +T  HL   +    +L AQ
Sbjct: 1634 QLRSLEQLQKENKELRAEAERLGHEL----QQAGLKTKEAEQTCRHL---TAQVRSLEAQ 1686

Query: 155  TYLLNPEMDSVLQSSLSSESWPIPEPE-WPAQTAQLDSLKL------PLSLVSTLDPGTC 207
                + ++  + +  +++++    EP+  P     +DSL L      PLS+ S L P T 
Sbjct: 1687 VAHADQQLRDLGKFQVATDALKSREPQAKPQLDLSIDSLDLSCEEGTPLSITSKL-PRTQ 1745

Query: 208  LAAVTVEPGLPAQRLQEK 225
                +V PG PA  + ++
Sbjct: 1746 PDGTSV-PGEPASPISQR 1762


>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
          Length = 4547

 Score = 37.4 bits (85), Expect = 0.014
 Identities = 25/105 (23%), Positives = 51/105 (48%), Gaps = 13/105 (12%)

Query: 12   EDPRLRAQQLHHRVLTLQCQLRDQGAAHQASLDEATRLQEELQAKLEELQKKQHEAKLAV 71
            E  + + +QL    +    QLR++    Q  +++    ++ L A +EE +++QHEA+  V
Sbjct: 2510 EQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE---RQRLVASMEEARRRQHEAEEGV 2566

Query: 72   TPLKAKIASLVRKCRERNRLIT----------HLLQELHRHGLGN 106
               + ++  L ++ R++  L+            LL+E HR  L +
Sbjct: 2567 RRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAH 2611



 Score = 28.1 bits (61), Expect = 8.7
 Identities = 22/83 (26%), Positives = 39/83 (46%), Gaps = 6/83 (7%)

Query: 11   EEDPRLRAQQL---HHRVLTLQCQLRDQ---GAAHQASLDEATRLQEELQAKLEELQKKQ 64
            EE+ RL  QQ      R+  ++  L  Q     AH  +  +A R  +ELQ +++E   ++
Sbjct: 1345 EEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRR 1404

Query: 65   HEAKLAVTPLKAKIASLVRKCRE 87
             EA +     K  I   +++ R+
Sbjct: 1405 EEAAVDAQQQKRSIQEELQQLRQ 1427



 Score = 28.1 bits (61), Expect = 8.7
 Identities = 21/67 (31%), Positives = 32/67 (47%), Gaps = 4/67 (5%)

Query: 2    LRDSEAEVTEEDPRL-RAQQLHHRVLTLQCQLRDQGAAHQASLDEATRLQEELQAKLEEL 60
            L+   A   E+  +L R+ Q  H  +    QLR++         EA R +EE + +LE  
Sbjct: 1578 LQSKRASFAEKTAQLERSLQEEHVAVA---QLREEAERRAQQQAEAERAREEAERELERW 1634

Query: 61   QKKQHEA 67
            Q K +EA
Sbjct: 1635 QLKANEA 1641


>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
          Length = 4551

 Score = 37.4 bits (85), Expect = 0.014
 Identities = 25/105 (23%), Positives = 51/105 (48%), Gaps = 13/105 (12%)

Query: 12   EDPRLRAQQLHHRVLTLQCQLRDQGAAHQASLDEATRLQEELQAKLEELQKKQHEAKLAV 71
            E  + + +QL    +    QLR++    Q  +++    ++ L A +EE +++QHEA+  V
Sbjct: 2514 EQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE---RQRLVASMEEARRRQHEAEEGV 2570

Query: 72   TPLKAKIASLVRKCRERNRLIT----------HLLQELHRHGLGN 106
               + ++  L ++ R++  L+            LL+E HR  L +
Sbjct: 2571 RRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAH 2615



 Score = 28.1 bits (61), Expect = 8.7
 Identities = 22/83 (26%), Positives = 39/83 (46%), Gaps = 6/83 (7%)

Query: 11   EEDPRLRAQQL---HHRVLTLQCQLRDQ---GAAHQASLDEATRLQEELQAKLEELQKKQ 64
            EE+ RL  QQ      R+  ++  L  Q     AH  +  +A R  +ELQ +++E   ++
Sbjct: 1349 EEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRR 1408

Query: 65   HEAKLAVTPLKAKIASLVRKCRE 87
             EA +     K  I   +++ R+
Sbjct: 1409 EEAAVDAQQQKRSIQEELQQLRQ 1431



 Score = 28.1 bits (61), Expect = 8.7
 Identities = 21/67 (31%), Positives = 32/67 (47%), Gaps = 4/67 (5%)

Query: 2    LRDSEAEVTEEDPRL-RAQQLHHRVLTLQCQLRDQGAAHQASLDEATRLQEELQAKLEEL 60
            L+   A   E+  +L R+ Q  H  +    QLR++         EA R +EE + +LE  
Sbjct: 1582 LQSKRASFAEKTAQLERSLQEEHVAVA---QLREEAERRAQQQAEAERAREEAERELERW 1638

Query: 61   QKKQHEA 67
            Q K +EA
Sbjct: 1639 QLKANEA 1645


>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
          Length = 4547

 Score = 37.4 bits (85), Expect = 0.014
 Identities = 25/105 (23%), Positives = 51/105 (48%), Gaps = 13/105 (12%)

Query: 12   EDPRLRAQQLHHRVLTLQCQLRDQGAAHQASLDEATRLQEELQAKLEELQKKQHEAKLAV 71
            E  + + +QL    +    QLR++    Q  +++    ++ L A +EE +++QHEA+  V
Sbjct: 2510 EQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE---RQRLVASMEEARRRQHEAEEGV 2566

Query: 72   TPLKAKIASLVRKCRERNRLIT----------HLLQELHRHGLGN 106
               + ++  L ++ R++  L+            LL+E HR  L +
Sbjct: 2567 RRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAH 2611



 Score = 28.1 bits (61), Expect = 8.7
 Identities = 22/83 (26%), Positives = 39/83 (46%), Gaps = 6/83 (7%)

Query: 11   EEDPRLRAQQL---HHRVLTLQCQLRDQ---GAAHQASLDEATRLQEELQAKLEELQKKQ 64
            EE+ RL  QQ      R+  ++  L  Q     AH  +  +A R  +ELQ +++E   ++
Sbjct: 1345 EEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRR 1404

Query: 65   HEAKLAVTPLKAKIASLVRKCRE 87
             EA +     K  I   +++ R+
Sbjct: 1405 EEAAVDAQQQKRSIQEELQQLRQ 1427



 Score = 28.1 bits (61), Expect = 8.7
 Identities = 21/67 (31%), Positives = 32/67 (47%), Gaps = 4/67 (5%)

Query: 2    LRDSEAEVTEEDPRL-RAQQLHHRVLTLQCQLRDQGAAHQASLDEATRLQEELQAKLEEL 60
            L+   A   E+  +L R+ Q  H  +    QLR++         EA R +EE + +LE  
Sbjct: 1578 LQSKRASFAEKTAQLERSLQEEHVAVA---QLREEAERRAQQQAEAERAREEAERELERW 1634

Query: 61   QKKQHEA 67
            Q K +EA
Sbjct: 1635 QLKANEA 1641


>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
          Length = 4515

 Score = 37.4 bits (85), Expect = 0.014
 Identities = 25/105 (23%), Positives = 51/105 (48%), Gaps = 13/105 (12%)

Query: 12   EDPRLRAQQLHHRVLTLQCQLRDQGAAHQASLDEATRLQEELQAKLEELQKKQHEAKLAV 71
            E  + + +QL    +    QLR++    Q  +++    ++ L A +EE +++QHEA+  V
Sbjct: 2478 EQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE---RQRLVASMEEARRRQHEAEEGV 2534

Query: 72   TPLKAKIASLVRKCRERNRLIT----------HLLQELHRHGLGN 106
               + ++  L ++ R++  L+            LL+E HR  L +
Sbjct: 2535 RRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAH 2579



 Score = 28.1 bits (61), Expect = 8.7
 Identities = 22/83 (26%), Positives = 39/83 (46%), Gaps = 6/83 (7%)

Query: 11   EEDPRLRAQQL---HHRVLTLQCQLRDQ---GAAHQASLDEATRLQEELQAKLEELQKKQ 64
            EE+ RL  QQ      R+  ++  L  Q     AH  +  +A R  +ELQ +++E   ++
Sbjct: 1313 EEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRR 1372

Query: 65   HEAKLAVTPLKAKIASLVRKCRE 87
             EA +     K  I   +++ R+
Sbjct: 1373 EEAAVDAQQQKRSIQEELQQLRQ 1395



 Score = 28.1 bits (61), Expect = 8.7
 Identities = 21/67 (31%), Positives = 32/67 (47%), Gaps = 4/67 (5%)

Query: 2    LRDSEAEVTEEDPRL-RAQQLHHRVLTLQCQLRDQGAAHQASLDEATRLQEELQAKLEEL 60
            L+   A   E+  +L R+ Q  H  +    QLR++         EA R +EE + +LE  
Sbjct: 1546 LQSKRASFAEKTAQLERSLQEEHVAVA---QLREEAERRAQQQAEAERAREEAERELERW 1602

Query: 61   QKKQHEA 67
            Q K +EA
Sbjct: 1603 QLKANEA 1609


>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
          Length = 4684

 Score = 37.4 bits (85), Expect = 0.014
 Identities = 25/105 (23%), Positives = 51/105 (48%), Gaps = 13/105 (12%)

Query: 12   EDPRLRAQQLHHRVLTLQCQLRDQGAAHQASLDEATRLQEELQAKLEELQKKQHEAKLAV 71
            E  + + +QL    +    QLR++    Q  +++    ++ L A +EE +++QHEA+  V
Sbjct: 2647 EQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE---RQRLVASMEEARRRQHEAEEGV 2703

Query: 72   TPLKAKIASLVRKCRERNRLIT----------HLLQELHRHGLGN 106
               + ++  L ++ R++  L+            LL+E HR  L +
Sbjct: 2704 RRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAH 2748



 Score = 28.1 bits (61), Expect = 8.7
 Identities = 22/83 (26%), Positives = 39/83 (46%), Gaps = 6/83 (7%)

Query: 11   EEDPRLRAQQL---HHRVLTLQCQLRDQ---GAAHQASLDEATRLQEELQAKLEELQKKQ 64
            EE+ RL  QQ      R+  ++  L  Q     AH  +  +A R  +ELQ +++E   ++
Sbjct: 1482 EEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRR 1541

Query: 65   HEAKLAVTPLKAKIASLVRKCRE 87
             EA +     K  I   +++ R+
Sbjct: 1542 EEAAVDAQQQKRSIQEELQQLRQ 1564



 Score = 28.1 bits (61), Expect = 8.7
 Identities = 21/67 (31%), Positives = 32/67 (47%), Gaps = 4/67 (5%)

Query: 2    LRDSEAEVTEEDPRL-RAQQLHHRVLTLQCQLRDQGAAHQASLDEATRLQEELQAKLEEL 60
            L+   A   E+  +L R+ Q  H  +    QLR++         EA R +EE + +LE  
Sbjct: 1715 LQSKRASFAEKTAQLERSLQEEHVAVA---QLREEAERRAQQQAEAERAREEAERELERW 1771

Query: 61   QKKQHEA 67
            Q K +EA
Sbjct: 1772 QLKANEA 1778


>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
          Length = 4525

 Score = 37.4 bits (85), Expect = 0.014
 Identities = 25/105 (23%), Positives = 51/105 (48%), Gaps = 13/105 (12%)

Query: 12   EDPRLRAQQLHHRVLTLQCQLRDQGAAHQASLDEATRLQEELQAKLEELQKKQHEAKLAV 71
            E  + + +QL    +    QLR++    Q  +++    ++ L A +EE +++QHEA+  V
Sbjct: 2488 EQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE---RQRLVASMEEARRRQHEAEEGV 2544

Query: 72   TPLKAKIASLVRKCRERNRLIT----------HLLQELHRHGLGN 106
               + ++  L ++ R++  L+            LL+E HR  L +
Sbjct: 2545 RRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAH 2589



 Score = 28.1 bits (61), Expect = 8.7
 Identities = 22/83 (26%), Positives = 39/83 (46%), Gaps = 6/83 (7%)

Query: 11   EEDPRLRAQQL---HHRVLTLQCQLRDQ---GAAHQASLDEATRLQEELQAKLEELQKKQ 64
            EE+ RL  QQ      R+  ++  L  Q     AH  +  +A R  +ELQ +++E   ++
Sbjct: 1323 EEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRR 1382

Query: 65   HEAKLAVTPLKAKIASLVRKCRE 87
             EA +     K  I   +++ R+
Sbjct: 1383 EEAAVDAQQQKRSIQEELQQLRQ 1405



 Score = 28.1 bits (61), Expect = 8.7
 Identities = 21/67 (31%), Positives = 32/67 (47%), Gaps = 4/67 (5%)

Query: 2    LRDSEAEVTEEDPRL-RAQQLHHRVLTLQCQLRDQGAAHQASLDEATRLQEELQAKLEEL 60
            L+   A   E+  +L R+ Q  H  +    QLR++         EA R +EE + +LE  
Sbjct: 1556 LQSKRASFAEKTAQLERSLQEEHVAVA---QLREEAERRAQQQAEAERAREEAERELERW 1612

Query: 61   QKKQHEA 67
            Q K +EA
Sbjct: 1613 QLKANEA 1619


>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
          Length = 4533

 Score = 37.4 bits (85), Expect = 0.014
 Identities = 25/105 (23%), Positives = 51/105 (48%), Gaps = 13/105 (12%)

Query: 12   EDPRLRAQQLHHRVLTLQCQLRDQGAAHQASLDEATRLQEELQAKLEELQKKQHEAKLAV 71
            E  + + +QL    +    QLR++    Q  +++    ++ L A +EE +++QHEA+  V
Sbjct: 2496 EQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE---RQRLVASMEEARRRQHEAEEGV 2552

Query: 72   TPLKAKIASLVRKCRERNRLIT----------HLLQELHRHGLGN 106
               + ++  L ++ R++  L+            LL+E HR  L +
Sbjct: 2553 RRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAH 2597



 Score = 28.1 bits (61), Expect = 8.7
 Identities = 22/83 (26%), Positives = 39/83 (46%), Gaps = 6/83 (7%)

Query: 11   EEDPRLRAQQL---HHRVLTLQCQLRDQ---GAAHQASLDEATRLQEELQAKLEELQKKQ 64
            EE+ RL  QQ      R+  ++  L  Q     AH  +  +A R  +ELQ +++E   ++
Sbjct: 1331 EEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRR 1390

Query: 65   HEAKLAVTPLKAKIASLVRKCRE 87
             EA +     K  I   +++ R+
Sbjct: 1391 EEAAVDAQQQKRSIQEELQQLRQ 1413



 Score = 28.1 bits (61), Expect = 8.7
 Identities = 21/67 (31%), Positives = 32/67 (47%), Gaps = 4/67 (5%)

Query: 2    LRDSEAEVTEEDPRL-RAQQLHHRVLTLQCQLRDQGAAHQASLDEATRLQEELQAKLEEL 60
            L+   A   E+  +L R+ Q  H  +    QLR++         EA R +EE + +LE  
Sbjct: 1564 LQSKRASFAEKTAQLERSLQEEHVAVA---QLREEAERRAQQQAEAERAREEAERELERW 1620

Query: 61   QKKQHEA 67
            Q K +EA
Sbjct: 1621 QLKANEA 1627


>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
          Length = 4574

 Score = 37.4 bits (85), Expect = 0.014
 Identities = 25/105 (23%), Positives = 51/105 (48%), Gaps = 13/105 (12%)

Query: 12   EDPRLRAQQLHHRVLTLQCQLRDQGAAHQASLDEATRLQEELQAKLEELQKKQHEAKLAV 71
            E  + + +QL    +    QLR++    Q  +++    ++ L A +EE +++QHEA+  V
Sbjct: 2537 EQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE---RQRLVASMEEARRRQHEAEEGV 2593

Query: 72   TPLKAKIASLVRKCRERNRLIT----------HLLQELHRHGLGN 106
               + ++  L ++ R++  L+            LL+E HR  L +
Sbjct: 2594 RRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAH 2638



 Score = 28.1 bits (61), Expect = 8.7
 Identities = 22/83 (26%), Positives = 39/83 (46%), Gaps = 6/83 (7%)

Query: 11   EEDPRLRAQQL---HHRVLTLQCQLRDQ---GAAHQASLDEATRLQEELQAKLEELQKKQ 64
            EE+ RL  QQ      R+  ++  L  Q     AH  +  +A R  +ELQ +++E   ++
Sbjct: 1372 EEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRR 1431

Query: 65   HEAKLAVTPLKAKIASLVRKCRE 87
             EA +     K  I   +++ R+
Sbjct: 1432 EEAAVDAQQQKRSIQEELQQLRQ 1454



 Score = 28.1 bits (61), Expect = 8.7
 Identities = 21/67 (31%), Positives = 32/67 (47%), Gaps = 4/67 (5%)

Query: 2    LRDSEAEVTEEDPRL-RAQQLHHRVLTLQCQLRDQGAAHQASLDEATRLQEELQAKLEEL 60
            L+   A   E+  +L R+ Q  H  +    QLR++         EA R +EE + +LE  
Sbjct: 1605 LQSKRASFAEKTAQLERSLQEEHVAVA---QLREEAERRAQQQAEAERAREEAERELERW 1661

Query: 61   QKKQHEA 67
            Q K +EA
Sbjct: 1662 QLKANEA 1668


>gi|169204908 PREDICTED: similar to Thyroid hormone receptor
           interactor 11 [Homo sapiens]
          Length = 352

 Score = 36.2 bits (82), Expect = 0.032
 Identities = 33/107 (30%), Positives = 56/107 (52%), Gaps = 15/107 (14%)

Query: 17  RAQQLHHRVLTLQCQLRDQGAAHQASLDEATRLQEELQAK---LEELQKKQHEAKLAVTP 73
           +A+ L  +V++LQ +L +  AA    LD A+RL E+L  K   +EEL+K+    +  +  
Sbjct: 81  KAESLERKVISLQERLDEADAA----LDSASRLTEQLDLKEEQIEELKKQNEFQQEMLDD 136

Query: 74  LKAKIASL-------VRKCRERNRLITHL-LQELHRHGLGNLLLSEL 112
           ++ K+ +L       V K   RN  I+H  + +  RH +  L+ S L
Sbjct: 137 VQKKLVNLANSLEGKVDKVLMRNLFISHFHMPKNQRHEVLRLMGSIL 183


>gi|169205597 PREDICTED: similar to Thyroid hormone receptor
           interactor 11 [Homo sapiens]
          Length = 352

 Score = 36.2 bits (82), Expect = 0.032
 Identities = 33/107 (30%), Positives = 56/107 (52%), Gaps = 15/107 (14%)

Query: 17  RAQQLHHRVLTLQCQLRDQGAAHQASLDEATRLQEELQAK---LEELQKKQHEAKLAVTP 73
           +A+ L  +V++LQ +L +  AA    LD A+RL E+L  K   +EEL+K+    +  +  
Sbjct: 81  KAESLERKVISLQERLDEADAA----LDSASRLTEQLDLKEEQIEELKKQNEFQQEMLDD 136

Query: 74  LKAKIASL-------VRKCRERNRLITHL-LQELHRHGLGNLLLSEL 112
           ++ K+ +L       V K   RN  I+H  + +  RH +  L+ S L
Sbjct: 137 VQKKLVNLANSLEGKVDKVLMRNLFISHFHMPKNQRHEVLRLMGSIL 183


>gi|169203883 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 352

 Score = 36.2 bits (82), Expect = 0.032
 Identities = 33/107 (30%), Positives = 56/107 (52%), Gaps = 15/107 (14%)

Query: 17  RAQQLHHRVLTLQCQLRDQGAAHQASLDEATRLQEELQAK---LEELQKKQHEAKLAVTP 73
           +A+ L  +V++LQ +L +  AA    LD A+RL E+L  K   +EEL+K+    +  +  
Sbjct: 81  KAESLERKVISLQERLDEADAA----LDSASRLTEQLDLKEEQIEELKKQNEFQQEMLDD 136

Query: 74  LKAKIASL-------VRKCRERNRLITHL-LQELHRHGLGNLLLSEL 112
           ++ K+ +L       V K   RN  I+H  + +  RH +  L+ S L
Sbjct: 137 VQKKLVNLANSLEGKVDKVLMRNLFISHFHMPKNQRHEVLRLMGSIL 183


>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
          Length = 2017

 Score = 36.2 bits (82), Expect = 0.032
 Identities = 44/163 (26%), Positives = 73/163 (44%), Gaps = 13/163 (7%)

Query: 13   DPRLRAQQLHHRVLTLQCQLRDQGAAHQASLDEATRLQEELQAKLEELQKKQHEAKLAVT 72
            D  L AQ+L       Q  LR+Q AAH+  L    RLQ E +A   EL+ ++ + +   +
Sbjct: 965  DKELMAQKLVQAEREAQASLREQRAAHEEDLQ---RLQREKEAAWRELEAERAQLQ---S 1018

Query: 73   PLKAKIASLVRKCRERNRLITHLLQELHRHGLGNLLLSELAQNMLNDVALAEYTATFLAP 132
             L+ +   L+ +       ++  +  L +     LLL+E  +     ++L E   T L+ 
Sbjct: 1019 QLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQQA--LSLKESEKTALSE 1076

Query: 133  GVPETSHHL-DVKSEMTAALR-AQTYLLNPEMDSVLQSSLSSE 173
             +  T H L  +  EM    R AQ+     E D    ++L+SE
Sbjct: 1077 KLMGTRHSLATISLEMERQKRDAQS---RQEQDRSTVNALTSE 1116



 Score = 28.1 bits (61), Expect = 8.7
 Identities = 28/101 (27%), Positives = 44/101 (43%), Gaps = 12/101 (11%)

Query: 3   RDSEAEVT---EEDPRLRAQQLHHRVLT--LQCQLRDQGAAHQASLD-------EATRLQ 50
           R +E E T   EE  RL   +L   V    L+  LR    A +A          E ++LQ
Sbjct: 774 RQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQ 833

Query: 51  EELQAKLEELQKKQHEAKLAVTPLKAKIASLVRKCRERNRL 91
           E+L     +L  ++ E + A    + ++ +L R  RE+  L
Sbjct: 834 EQLAQLSRQLSGREQELEQARREAQRQVEALERAAREKEAL 874


>gi|217330634 serine/threonine kinase 36 [Homo sapiens]
          Length = 1315

 Score = 35.4 bits (80), Expect = 0.055
 Identities = 36/118 (30%), Positives = 54/118 (45%), Gaps = 9/118 (7%)

Query: 145 SEMTAAL--RAQTYLLNPEMDSVLQSSLSSESWPIPEPEWPAQTAQLDSLKLPLSLVS-T 201
           SEM   L  R    L  PE  S  +  LS  S P PEP+W   + Q  +  L L++ + T
Sbjct: 875 SEMWTVLWHRFSMVLRLPEEASAQEGELSLSSPPSPEPDWTLISPQGMAALLSLAMATFT 934

Query: 202 LDPGTCLAAVTVEPGLPAQRLQEKGGMPCPAL--QVDNVPAPSELLSPARILAFHQEL 257
            +P  CL+ ++    +    L+    + CP+   Q+   P  SE L P  +L+  Q L
Sbjct: 935 QEPQLCLSCLSQHGSILMSILKH---LLCPSFLNQLRQAPHGSEFL-PVVVLSVCQLL 988


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score = 35.0 bits (79), Expect = 0.071
 Identities = 36/173 (20%), Positives = 75/173 (43%), Gaps = 13/173 (7%)

Query: 2    LRDSEAEVTEEDPRLRAQQLHHRVLTLQCQLRDQGAAHQASLDEATRLQEELQAKLEELQ 61
            L+D EA++  E       ++  ++  LQ Q++D    +Q  L+EA   ++E+ A+ +E +
Sbjct: 1626 LKDLEAQI--EAANKARDEVIKQLRKLQAQMKD----YQRELEEARASRDEIFAQSKESE 1679

Query: 62   KKQHEAKLAVTPLKAKIASLVRKCRERNRLITHLLQELHRHGLGNLLLSELAQNMLNDVA 121
            KK    +  +  L+ ++AS  R  R   +    L  E+     G   L       L++  
Sbjct: 1680 KKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSAL-------LDEKR 1732

Query: 122  LAEYTATFLAPGVPETSHHLDVKSEMTAALRAQTYLLNPEMDSVLQSSLSSES 174
              E     L   + E   ++++ ++       Q   LN E+ +   ++  S++
Sbjct: 1733 RLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDN 1785



 Score = 32.0 bits (71), Expect = 0.61
 Identities = 23/106 (21%), Positives = 52/106 (49%), Gaps = 11/106 (10%)

Query: 8   EVTEEDPRLRAQ-----QLHHRVLTLQCQLRDQGAAHQASLDEATRLQEELQA------K 56
           +VT ++  L+A+     ++  +   ++ +L +    HQ  L+E   L E+LQA      +
Sbjct: 846 QVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAE 905

Query: 57  LEELQKKQHEAKLAVTPLKAKIASLVRKCRERNRLITHLLQELHRH 102
            EE++ +    K  +  +   + S V +  ERN+++ +  +++  H
Sbjct: 906 AEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAH 951


>gi|45446749 kinesin family member 5A [Homo sapiens]
          Length = 1032

 Score = 35.0 bits (79), Expect = 0.071
 Identities = 24/75 (32%), Positives = 38/75 (50%), Gaps = 11/75 (14%)

Query: 2   LRDSEAEVTEEDPRLRAQQL--------HHRVLTLQCQLRDQGAAHQASLDEATRLQEEL 53
           L+D E +  + D   +A +L        HHR L    +LRD+    Q ++DE   L ++L
Sbjct: 682 LKDKEPDTQDADEVKKALELQMESHREAHHRQLA---RLRDEINEKQKTIDELKDLNQKL 738

Query: 54  QAKLEELQKKQHEAK 68
           Q +LE+LQ    + K
Sbjct: 739 QLELEKLQADYEKLK 753


>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
           isoform 2 [Homo sapiens]
          Length = 1320

 Score = 35.0 bits (79), Expect = 0.071
 Identities = 42/173 (24%), Positives = 69/173 (39%), Gaps = 19/173 (10%)

Query: 9   VTEEDPRLRAQQLHHRVLTLQCQLRDQGAAHQASLDEATRLQEELQAKLEELQKKQHEAK 68
           + E   R+  Q+   R L  Q Q R++ A  Q   ++  R QEE + +LEEL++++ E +
Sbjct: 392 LAERQKRIEQQKEQRRRLEEQ-QRREREARRQQEREQRRREQEE-KRRLEELERRRKEEE 449

Query: 69  LAVTPLKAKIASLVRKCRERNRLITHLLQELHRHGLGNLLLSELAQNMLNDVALAEYTAT 128
                 + +     R+       I   L+E  RH      L  L Q +L + A+      
Sbjct: 450 -----ERRRAEEEKRRVEREQEYIRRQLEEEQRH------LEVLQQQLLQEQAM------ 492

Query: 129 FLAPGVPETSHHLDVKSEMTAALRAQTYLLNPEMDSVLQSSLSSESWPIPEPE 181
            L     E   H   +       + Q YLL+ + D        S+  P P+ E
Sbjct: 493 LLECRWREMEEHRQAERLQRQLQQEQAYLLSLQHDHRRPHPQHSQQPPPPQQE 545


>gi|149363664 septin 8 isoform d [Homo sapiens]
          Length = 369

 Score = 35.0 bits (79), Expect = 0.071
 Identities = 30/99 (30%), Positives = 44/99 (44%), Gaps = 6/99 (6%)

Query: 2   LRDSEAEVTEEDPRLRAQQLHHRVLTLQCQLRDQGAAHQASLDEATRLQEELQAK----L 57
           LR+    V  ED R +    H+  L  +C+L + G        +   LQE  +AK    L
Sbjct: 216 LREMLIRVNMEDLREQTHSRHYE-LYRRCKLEEMGFQDSDGDSQPFSLQETYEAKRKEFL 274

Query: 58  EELQKKQHEAK-LAVTPLKAKIASLVRKCRERNRLITHL 95
            ELQ+K+ E + + V  +K     L  K RE +    HL
Sbjct: 275 SELQRKEEEMRQMFVNKVKETELELKEKERELHEKFEHL 313


>gi|149363638 septin 8 isoform c [Homo sapiens]
          Length = 442

 Score = 35.0 bits (79), Expect = 0.071
 Identities = 30/99 (30%), Positives = 44/99 (44%), Gaps = 6/99 (6%)

Query: 2   LRDSEAEVTEEDPRLRAQQLHHRVLTLQCQLRDQGAAHQASLDEATRLQEELQAK----L 57
           LR+    V  ED R +    H+  L  +C+L + G        +   LQE  +AK    L
Sbjct: 276 LREMLIRVNMEDLREQTHSRHYE-LYRRCKLEEMGFQDSDGDSQPFSLQETYEAKRKEFL 334

Query: 58  EELQKKQHEAK-LAVTPLKAKIASLVRKCRERNRLITHL 95
            ELQ+K+ E + + V  +K     L  K RE +    HL
Sbjct: 335 SELQRKEEEMRQMFVNKVKETELELKEKERELHEKFEHL 373


>gi|149363689 septin 8 isoform a [Homo sapiens]
          Length = 483

 Score = 35.0 bits (79), Expect = 0.071
 Identities = 30/99 (30%), Positives = 44/99 (44%), Gaps = 6/99 (6%)

Query: 2   LRDSEAEVTEEDPRLRAQQLHHRVLTLQCQLRDQGAAHQASLDEATRLQEELQAK----L 57
           LR+    V  ED R +    H+  L  +C+L + G        +   LQE  +AK    L
Sbjct: 276 LREMLIRVNMEDLREQTHSRHYE-LYRRCKLEEMGFQDSDGDSQPFSLQETYEAKRKEFL 334

Query: 58  EELQKKQHEAK-LAVTPLKAKIASLVRKCRERNRLITHL 95
            ELQ+K+ E + + V  +K     L  K RE +    HL
Sbjct: 335 SELQRKEEEMRQMFVNKVKETELELKEKERELHEKFEHL 373


>gi|149363661 septin 8 isoform b [Homo sapiens]
          Length = 429

 Score = 35.0 bits (79), Expect = 0.071
 Identities = 30/99 (30%), Positives = 44/99 (44%), Gaps = 6/99 (6%)

Query: 2   LRDSEAEVTEEDPRLRAQQLHHRVLTLQCQLRDQGAAHQASLDEATRLQEELQAK----L 57
           LR+    V  ED R +    H+  L  +C+L + G        +   LQE  +AK    L
Sbjct: 276 LREMLIRVNMEDLREQTHSRHYE-LYRRCKLEEMGFQDSDGDSQPFSLQETYEAKRKEFL 334

Query: 58  EELQKKQHEAK-LAVTPLKAKIASLVRKCRERNRLITHL 95
            ELQ+K+ E + + V  +K     L  K RE +    HL
Sbjct: 335 SELQRKEEEMRQMFVNKVKETELELKEKERELHEKFEHL 373


>gi|24308303 SH3-binding domain protein 5-like [Homo sapiens]
          Length = 393

 Score = 35.0 bits (79), Expect = 0.071
 Identities = 32/111 (28%), Positives = 56/111 (50%), Gaps = 7/111 (6%)

Query: 1   MLRDSEAEVTE-EDPRLRAQQLHHRVLTLQCQLRDQGAAHQASLDEA---TRLQEELQAK 56
           ML  +  +V E E+ RLR ++ H RV  L  Q   +  A Q +L  A   +R   EL+A+
Sbjct: 172 MLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELKAQ 231

Query: 57  LEELQKKQHEAKLAVTPLKAKIASLVRKCRERNRLITHLLQELHRHGLGNL 107
             ++  ++H+AK  VT L+ ++A    +     R +  + +++H    G L
Sbjct: 232 FSQI-LEEHKAK--VTELEQQVAQAKTRYSVALRNLEQISEQIHARRRGGL 279


>gi|239787092 A20-binding inhibitor of NF-kappaB activation 2
           isoform 1 [Homo sapiens]
          Length = 429

 Score = 34.3 bits (77), Expect = 0.12
 Identities = 43/185 (23%), Positives = 75/185 (40%), Gaps = 10/185 (5%)

Query: 21  LHHRVLTLQCQLRDQ--GAAHQASLDEATRLQEELQAKLEELQ----KKQHEAKLAVTPL 74
           L  +V   + QLR Q  GAA      E  RL E L+ K  E+Q    + QHE +  V  L
Sbjct: 67  LLEQVARFREQLRRQEGGAAEAQMRQEIERLTERLEEKEREMQQLLSQPQHEREKEVVLL 126

Query: 75  KAKIASLVRKCRERNRLITHLLQELHRHGLGNLLLSELAQNMLNDVALAEYTATFLAPGV 134
           +  +A   R     + L   L  E H+        + + Q++   +   ++    +    
Sbjct: 127 RRSMAEGERARAASDVLCRSLANETHQLRRTLTATAHMCQHLAKCLDERQHAQRNVGERS 186

Query: 135 PETSHHLDVKSEMTAA---LRAQTYLLNPEMDSVLQSSLSSESWPIPEPEW-PAQTAQLD 190
           P+ S H D  + + +    L+ +  LL  ++  V   +   + +     E+     AQL 
Sbjct: 187 PDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNAKWQRYNASRDEYVRGLHAQLR 246

Query: 191 SLKLP 195
            L++P
Sbjct: 247 GLQIP 251


>gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]
          Length = 488

 Score = 34.3 bits (77), Expect = 0.12
 Identities = 31/94 (32%), Positives = 43/94 (45%), Gaps = 15/94 (15%)

Query: 22  HHRVLTLQCQLRDQGAA---------HQAS----LDEATR-LQEELQAKLEELQKKQHEA 67
           HH  L+L C   DQ A          H+A     LD+AT+  +E+LQ  LE L++K  E 
Sbjct: 110 HHEALSLFCY-EDQEAVCLICAISHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEI 168

Query: 68  KLAVTPLKAKIASLVRKCRERNRLITHLLQELHR 101
               +  + K   L R    R + I    +ELHR
Sbjct: 169 TRCKSSEEKKPGELKRLVESRRQQILREFEELHR 202


>gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]
          Length = 518

 Score = 34.3 bits (77), Expect = 0.12
 Identities = 31/94 (32%), Positives = 43/94 (45%), Gaps = 15/94 (15%)

Query: 22  HHRVLTLQCQLRDQGAA---------HQAS----LDEATR-LQEELQAKLEELQKKQHEA 67
           HH  L+L C   DQ A          H+A     LD+AT+  +E+LQ  LE L++K  E 
Sbjct: 110 HHEALSLFCY-EDQEAVCLICAISHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEI 168

Query: 68  KLAVTPLKAKIASLVRKCRERNRLITHLLQELHR 101
               +  + K   L R    R + I    +ELHR
Sbjct: 169 TRCKSSEEKKPGELKRLVESRRQQILREFEELHR 202


>gi|32698688 citron [Homo sapiens]
          Length = 2027

 Score = 34.3 bits (77), Expect = 0.12
 Identities = 21/83 (25%), Positives = 43/83 (51%), Gaps = 5/83 (6%)

Query: 6   EAEVTEEDPRLRAQQLHHRVLTLQCQLRDQGAAHQASLDEATRLQEELQAKLEELQKKQH 65
           E+ +  E+ + +A +  H++L    + +DQG        +  ++  E Q K++ELQ+K  
Sbjct: 591 ESRLAAEEFKRKATECQHKLL----KAKDQGKPEVGEYAKLEKINAEQQLKIQELQEKLE 646

Query: 66  EAKLAVTPLKAKIASLVRKCRER 88
           +A  A T    ++   +R+ +ER
Sbjct: 647 KAVKASTE-ATELLQNIRQAKER 668



 Score = 28.5 bits (62), Expect = 6.7
 Identities = 19/80 (23%), Positives = 35/80 (43%)

Query: 23  HRVLTLQCQLRDQGAAHQASLDEATRLQEELQAKLEELQKKQHEAKLAVTPLKAKIASLV 82
           +R+L L+ +LR+    H+    E  R   ELQ  L+E + +    + A   L++++    
Sbjct: 849 NRLLELETRLREVSLEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALESQLRQAK 908

Query: 83  RKCRERNRLITHLLQELHRH 102
            +  E        +Q L  H
Sbjct: 909 TELEETTAEAEEEIQALTAH 928


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.128    0.362 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,833,352
Number of Sequences: 37866
Number of extensions: 507780
Number of successful extensions: 3719
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 79
Number of HSP's successfully gapped in prelim test: 212
Number of HSP's that attempted gapping in prelim test: 3176
Number of HSP's gapped (non-prelim): 746
length of query: 276
length of database: 18,247,518
effective HSP length: 101
effective length of query: 175
effective length of database: 14,423,052
effective search space: 2524034100
effective search space used: 2524034100
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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