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Search of human proteins with 46409282
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|46409282 OTU domain containing 6A [Homo sapiens]
(288 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|46409282 OTU domain containing 6A [Homo sapiens] 569 e-162
gi|157364937 OTU domain containing 6B [Homo sapiens] 320 7e-88
gi|149192871 OTU domain containing 3 [Homo sapiens] 53 4e-07
gi|33457350 OTU domain containing 5 isoform a [Homo sapiens] 52 5e-07
gi|209977021 OTU domain containing 5 isoform b [Homo sapiens] 51 1e-06
gi|209977019 OTU domain containing 5 isoform b [Homo sapiens] 51 1e-06
gi|56549694 enabled homolog isoform a [Homo sapiens] 49 5e-06
gi|39930375 enabled homolog isoform b [Homo sapiens] 49 5e-06
gi|209977067 OTU domain containing 5 isoform c [Homo sapiens] 47 2e-05
gi|148746195 trichohyalin [Homo sapiens] 44 2e-04
gi|4505101 microtubule-associated protein 7 [Homo sapiens] 44 2e-04
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 44 2e-04
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 43 3e-04
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 42 6e-04
gi|92859701 myosin VI [Homo sapiens] 42 6e-04
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 42 8e-04
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 42 8e-04
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 42 8e-04
gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti... 41 0.001
gi|55770834 centromere protein F [Homo sapiens] 41 0.001
gi|21735548 centrosomal protein 2 [Homo sapiens] 41 0.001
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 41 0.001
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 41 0.001
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 41 0.001
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 41 0.001
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 41 0.001
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 41 0.001
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 41 0.001
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 41 0.001
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 41 0.001
>gi|46409282 OTU domain containing 6A [Homo sapiens]
Length = 288
Score = 569 bits (1466), Expect = e-162
Identities = 288/288 (100%), Positives = 288/288 (100%)
Query: 1 MDDPKSEQQRILRRHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHR 60
MDDPKSEQQRILRRHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHR
Sbjct: 1 MDDPKSEQQRILRRHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHR 60
Query: 61 QELEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSEH 120
QELEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSEH
Sbjct: 61 QELEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSEH 120
Query: 121 LAGFKREEEEKLAAILGARGLEMKAIPADGHCMYRAIQDQLVFSVSVEMLRCRTASYMKK 180
LAGFKREEEEKLAAILGARGLEMKAIPADGHCMYRAIQDQLVFSVSVEMLRCRTASYMKK
Sbjct: 121 LAGFKREEEEKLAAILGARGLEMKAIPADGHCMYRAIQDQLVFSVSVEMLRCRTASYMKK 180
Query: 181 HVDEFLPFFSNPETSDSFGYDDFMIYCDNIVRTTAWGGQLELRALSHVLKTPIEVIQADS 240
HVDEFLPFFSNPETSDSFGYDDFMIYCDNIVRTTAWGGQLELRALSHVLKTPIEVIQADS
Sbjct: 181 HVDEFLPFFSNPETSDSFGYDDFMIYCDNIVRTTAWGGQLELRALSHVLKTPIEVIQADS 240
Query: 241 PTLIIGEEYVKKPIILVYLRYAYSLGEHYNSVTPLEAGAAGGVLPRLL 288
PTLIIGEEYVKKPIILVYLRYAYSLGEHYNSVTPLEAGAAGGVLPRLL
Sbjct: 241 PTLIIGEEYVKKPIILVYLRYAYSLGEHYNSVTPLEAGAAGGVLPRLL 288
>gi|157364937 OTU domain containing 6B [Homo sapiens]
Length = 323
Score = 320 bits (821), Expect = 7e-88
Identities = 156/275 (56%), Positives = 218/275 (79%), Gaps = 7/275 (2%)
Query: 7 EQQRILRRHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQELEKF 66
E++++LRRH++E++ELQA+I+ +KN+VPK DK +RKQL +DVA++E EM QKHR+ELE+
Sbjct: 41 EEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHREELEQL 100
Query: 67 Q---DDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSEHLAG 123
+ ++ I+SV +++ + LEN+PPR SKA ++RE+ + E+ER+E I +AE+ E+L G
Sbjct: 101 KLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIAEAEI-ENLTG 159
Query: 124 FKREEEEKLAAILGARGLEMKAIPADGHCMYRAIQDQLV---FSVSVEMLRCRTASYMKK 180
+ E EKLA IL AR LE+K IP+DGHCMY+AI+DQL +++V LR +TA YM+
Sbjct: 160 ARHMESEKLAQILAARQLEIKQIPSDGHCMYKAIEDQLKEKDCALTVVALRSQTAEYMQS 219
Query: 181 HVDEFLPFFSNPETSDSFGYDDFMIYCDNIVRTTAWGGQLELRALSHVLKTPIEVIQADS 240
HV++FLPF +NP T D + ++F YC++IV T AWGGQLELRALSH+L+TPIE+IQADS
Sbjct: 220 HVEDFLPFLTNPNTGDMYTPEEFQKYCEDIVNTAAWGGQLELRALSHILQTPIEIIQADS 279
Query: 241 PTLIIGEEYVKKPIILVYLRYAYSLGEHYNSVTPL 275
P +I+GEEY KKP+ILVY+R+AY LGEHYNSVT L
Sbjct: 280 PPIIVGEEYSKKPLILVYMRHAYGLGEHYNSVTRL 314
>gi|149192871 OTU domain containing 3 [Homo sapiens]
Length = 398
Score = 52.8 bits (125), Expect = 4e-07
Identities = 56/205 (27%), Positives = 91/205 (44%), Gaps = 35/205 (17%)
Query: 81 KMNLENRP---PRSSKAHRKRER------MESEERERQESIFQAEMSEHLAGFKREEEEK 131
K ++RP R ++A RKR+ + E R R ES E F +
Sbjct: 4 KQAAKSRPGSGSRKAEAERKRDERAARRALAKERRNRPESGGGGGCEEEFVSFANQ---- 59
Query: 132 LAAILGARGLEMKAIPADGHCMYRAIQDQLV-FSVSVEMLRCRTASYMKKHVDEFLPFFS 190
L A GL+++ +P DG+C++RA+ DQL S + R T YM K ++F PF
Sbjct: 60 ----LQALGLKLREVPGDGNCLFRALGDQLEGHSRNHLKHRQETVDYMIKQREDFEPFVE 115
Query: 191 NPETSDSFGYDD--FMIYCDNIVRTTAWGGQLELRALSHVLKTPIEVIQADSPT-LIIGE 247
DD F + ++ + + G + A + + + + Q ++P I G
Sbjct: 116 ----------DDIPFEKHVASLAKPGTFAGNDAIVAFARNHQLNVVIHQLNAPLWQIRGT 165
Query: 248 EYVKKPIILVYLRYAYSLGEHYNSV 272
E K + +++ Y Y GEHY+SV
Sbjct: 166 E--KSSVRELHIAYRY--GEHYDSV 186
>gi|33457350 OTU domain containing 5 isoform a [Homo sapiens]
Length = 571
Score = 52.4 bits (124), Expect = 5e-07
Identities = 39/149 (26%), Positives = 69/149 (46%), Gaps = 26/149 (17%)
Query: 134 AILGARGLEMKAIPADGHCMYRAIQDQLVFSVSV-EMLRCRTASYMKKHVDEFLPFFSNP 192
A+ +G +K + DG C++RA+ DQ+ + E++R Y+ K+ D +FSN
Sbjct: 206 ALRDKKGFIIKQMKEDGACLFRAVADQVYGDQDMHEVVRKHCMDYLMKNAD----YFSNY 261
Query: 193 ETSDSFGYDDFMIYCDNIVRTTAWGGQLELRALSHVLKTPIEVIQADSPTLIIGEEYVKK 252
T +DF Y + + G +E++A++ + P+EV Q + T + +
Sbjct: 262 VT------EDFTTYINRKRKNNCHGNHIEMQAMAEMYNRPVEVYQYSTGTSAV------E 309
Query: 253 PIILVY---------LRYAYSLGEHYNSV 272
PI + +R +Y HYNSV
Sbjct: 310 PINTFHGIHQNEDEPIRVSYHRNIHYNSV 338
>gi|209977021 OTU domain containing 5 isoform b [Homo sapiens]
Length = 566
Score = 51.2 bits (121), Expect = 1e-06
Identities = 39/149 (26%), Positives = 67/149 (44%), Gaps = 31/149 (20%)
Query: 134 AILGARGLEMKAIPADGHCMYRAIQDQLVFSVSV-EMLRCRTASYMKKHVDEFLPFFSNP 192
A+ +G +K + DG C++RA+ DQ+ + E++R Y+ K+ D +FSN
Sbjct: 206 ALRDKKGFIIKQMKEDGACLFRAVADQVYGDQDMHEVVRKHCMDYLMKNAD----YFSNY 261
Query: 193 ETSDSFGYDDFMIYCDNIVRTTAWGGQLELRALSHVLKTPIEVIQADSPTLIIGEEYVKK 252
T +DF Y + + G +E++A++ + P+EV Q Y +
Sbjct: 262 VT------EDFTTYINRKRKNNCHGNHIEMQAMAEMYNRPVEVYQ-----------YSTE 304
Query: 253 PIILVY---------LRYAYSLGEHYNSV 272
PI + +R +Y HYNSV
Sbjct: 305 PINTFHGIHQNEDEPIRVSYHRNIHYNSV 333
>gi|209977019 OTU domain containing 5 isoform b [Homo sapiens]
Length = 566
Score = 51.2 bits (121), Expect = 1e-06
Identities = 39/149 (26%), Positives = 67/149 (44%), Gaps = 31/149 (20%)
Query: 134 AILGARGLEMKAIPADGHCMYRAIQDQLVFSVSV-EMLRCRTASYMKKHVDEFLPFFSNP 192
A+ +G +K + DG C++RA+ DQ+ + E++R Y+ K+ D +FSN
Sbjct: 206 ALRDKKGFIIKQMKEDGACLFRAVADQVYGDQDMHEVVRKHCMDYLMKNAD----YFSNY 261
Query: 193 ETSDSFGYDDFMIYCDNIVRTTAWGGQLELRALSHVLKTPIEVIQADSPTLIIGEEYVKK 252
T +DF Y + + G +E++A++ + P+EV Q Y +
Sbjct: 262 VT------EDFTTYINRKRKNNCHGNHIEMQAMAEMYNRPVEVYQ-----------YSTE 304
Query: 253 PIILVY---------LRYAYSLGEHYNSV 272
PI + +R +Y HYNSV
Sbjct: 305 PINTFHGIHQNEDEPIRVSYHRNIHYNSV 333
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 48.9 bits (115), Expect = 5e-06
Identities = 36/135 (26%), Positives = 69/135 (51%), Gaps = 5/135 (3%)
Query: 4 PKSEQQRILRRHQRERQ-ELQAQIRSLKNSVPKTDKTKRKQLLQDVA---RMEAEMAQKH 59
P E+ I RR +E+Q + + + L+ + ++ +R++L ++ R+E E ++
Sbjct: 135 PSQEELEIQRRQLQEQQRQKELERERLERERMERERLERERLERERLERERLEQEQLERE 194
Query: 60 RQELEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSE 119
RQE E+ Q+ + +E ++ + R R + ++RER+E ERERQE Q ++
Sbjct: 195 RQERER-QERLERQERLERQERLERQERLDRERQERQERERLERLERERQERERQEQLER 253
Query: 120 HLAGFKREEEEKLAA 134
++RE AA
Sbjct: 254 EQLEWERERRISSAA 268
Score = 29.3 bits (64), Expect = 4.2
Identities = 25/102 (24%), Positives = 46/102 (45%), Gaps = 5/102 (4%)
Query: 32 SVPKTDKTKRKQLLQDVARMEAEMAQKHRQELEKFQDDSSIESVVEDLAKMNLENRPPRS 91
++P+ + Q+ ++ E E+ ++ QE ++ ++ E + + LE
Sbjct: 119 TLPRQNSQLPAQVQNGPSQEELEIQRRQLQEQQRQKELERERLERERMERERLERERLER 178
Query: 92 SKAHRKRERMESEERERQESIFQAEMSEHLAGFKR-EEEEKL 132
+ R+R E ERERQE E E L +R E +E+L
Sbjct: 179 ERLERERLEQEQLERERQE----RERQERLERQERLERQERL 216
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 48.9 bits (115), Expect = 5e-06
Identities = 36/135 (26%), Positives = 69/135 (51%), Gaps = 5/135 (3%)
Query: 4 PKSEQQRILRRHQRERQ-ELQAQIRSLKNSVPKTDKTKRKQLLQDVA---RMEAEMAQKH 59
P E+ I RR +E+Q + + + L+ + ++ +R++L ++ R+E E ++
Sbjct: 135 PSQEELEIQRRQLQEQQRQKELERERLERERMERERLERERLERERLERERLEQEQLERE 194
Query: 60 RQELEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSE 119
RQE E+ Q+ + +E ++ + R R + ++RER+E ERERQE Q ++
Sbjct: 195 RQERER-QERLERQERLERQERLERQERLDRERQERQERERLERLERERQERERQEQLER 253
Query: 120 HLAGFKREEEEKLAA 134
++RE AA
Sbjct: 254 EQLEWERERRISSAA 268
Score = 29.3 bits (64), Expect = 4.2
Identities = 25/102 (24%), Positives = 46/102 (45%), Gaps = 5/102 (4%)
Query: 32 SVPKTDKTKRKQLLQDVARMEAEMAQKHRQELEKFQDDSSIESVVEDLAKMNLENRPPRS 91
++P+ + Q+ ++ E E+ ++ QE ++ ++ E + + LE
Sbjct: 119 TLPRQNSQLPAQVQNGPSQEELEIQRRQLQEQQRQKELERERLERERMERERLERERLER 178
Query: 92 SKAHRKRERMESEERERQESIFQAEMSEHLAGFKR-EEEEKL 132
+ R+R E ERERQE E E L +R E +E+L
Sbjct: 179 ERLERERLEQEQLERERQE----RERQERLERQERLERQERL 216
>gi|209977067 OTU domain containing 5 isoform c [Homo sapiens]
Length = 349
Score = 47.0 bits (110), Expect = 2e-05
Identities = 36/134 (26%), Positives = 60/134 (44%), Gaps = 31/134 (23%)
Query: 149 DGHCMYRAIQDQLVFSVSV-EMLRCRTASYMKKHVDEFLPFFSNPETSDSFGYDDFMIYC 207
DG C++RA+ DQ+ + E++R Y+ K+ D +FSN T +DF Y
Sbjct: 4 DGACLFRAVADQVYGDQDMHEVVRKHCMDYLMKNAD----YFSNYVT------EDFTTYI 53
Query: 208 DNIVRTTAWGGQLELRALSHVLKTPIEVIQADSPTLIIGEEYVKKPIILVY--------- 258
+ + G +E++A++ + P+EV Q Y +PI +
Sbjct: 54 NRKRKNNCHGNHIEMQAMAEMYNRPVEVYQ-----------YSTEPINTFHGIHQNEDEP 102
Query: 259 LRYAYSLGEHYNSV 272
+R +Y HYNSV
Sbjct: 103 IRVSYHRNIHYNSV 116
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 43.9 bits (102), Expect = 2e-04
Identities = 28/134 (20%), Positives = 63/134 (47%), Gaps = 7/134 (5%)
Query: 3 DPKSEQQRILRRHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQE 62
+ + +Q++ R + ER+E + L+ + + +R+Q L+ E K ++E
Sbjct: 468 EQERRKQQLKRDQEEERRERWLK---LEEEERREQQERREQQLRREQEERREQRLKRQEE 524
Query: 63 LEKFQD----DSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMS 118
E+ Q + + E+ + L+ + + R+ +R++ E+ ER++ + + E
Sbjct: 525 EERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEE 584
Query: 119 EHLAGFKREEEEKL 132
KRE+EE+L
Sbjct: 585 RRQQRLKREQEERL 598
Score = 43.1 bits (100), Expect = 3e-04
Identities = 34/130 (26%), Positives = 66/130 (50%), Gaps = 6/130 (4%)
Query: 3 DPKSEQQRILRRHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQE 62
+ K EQ+R +R +RE++E + ++ + + + +++QL +D E K +E
Sbjct: 435 EQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEE 494
Query: 63 LEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSEHLA 122
+ Q + + + + + E R R + R ++R+ SE++ R+E Q E E L
Sbjct: 495 ERREQQERREQQLRREQEERR-EQRLKRQEEEERLQQRLRSEQQLRRE---QEERREQL- 549
Query: 123 GFKREEEEKL 132
KREEE++L
Sbjct: 550 -LKREEEKRL 558
Score = 42.4 bits (98), Expect = 5e-04
Identities = 35/135 (25%), Positives = 72/135 (53%), Gaps = 12/135 (8%)
Query: 2 DDPKSEQQRILRRHQRERQEL----QAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQ 57
++ + +Q+ LRR Q+ER+E + + L+ + + + +R++ Q++A E E A+
Sbjct: 637 EEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERRE--QELAEEEQEQAR 694
Query: 58 KH-RQELEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAE 116
+ + + K+Q E+ D + + +RP R + R+R+ E E+R R+ES Q +
Sbjct: 695 ERIKSRIPKWQWQLESEA---DARQSKVYSRP-RKQEGQRRRQEQE-EKRRRRESELQWQ 749
Query: 117 MSEHLAGFKREEEEK 131
E ++EEE++
Sbjct: 750 EEERAHRQQQEEEQR 764
Score = 40.4 bits (93), Expect = 0.002
Identities = 31/127 (24%), Positives = 61/127 (48%), Gaps = 11/127 (8%)
Query: 5 KSEQQRILRRHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQELE 64
K E+++ L + +RE Q L+ + ++ + K ++ +R+Q L+ E K R+E+E
Sbjct: 551 KREEEKRLEQERRE-QRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLK-REEVE 608
Query: 65 KFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSEHLAGF 124
+ + E+ + L+ P + + + E EER RQ+ + + +
Sbjct: 609 RLEQ--------EERREQRLKREEPEEERRQQLLKSEEQEER-RQQQLRREQQERREQRL 659
Query: 125 KREEEEK 131
KREEEE+
Sbjct: 660 KREEEEE 666
Score = 40.4 bits (93), Expect = 0.002
Identities = 40/146 (27%), Positives = 67/146 (45%), Gaps = 25/146 (17%)
Query: 2 DDPKSEQQRILR------------RHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVA 49
D+ + E++++LR R RE +ELQ + L + + +T+R+Q L+
Sbjct: 1024 DELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQL---LGEERETRRRQELERQY 1080
Query: 50 RMEAEMAQKH----RQELEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEE 105
R E E+ Q+ R+E EK + E+ E + R + R+R+ +E +
Sbjct: 1081 RKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQY 1140
Query: 106 RERQESIFQAEMSEHLAGFKREEEEK 131
RE +E Q E + L REE EK
Sbjct: 1141 REEEE--VQQEEEQLL----REEPEK 1160
Score = 40.4 bits (93), Expect = 0.002
Identities = 33/131 (25%), Positives = 62/131 (47%), Gaps = 7/131 (5%)
Query: 2 DDPKSEQQRILRRHQRERQELQAQIRSLKNSVP-KTDKTKRKQLLQDVARMEAEMAQKHR 60
++ ++ +++ L R R+ +ELQ + L P K + +R++ ++ ++ E Q R
Sbjct: 1066 EERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLR 1125
Query: 61 QELEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSEH 120
+E EK + E+ E + R R+R+ +E + RE +E Q E +
Sbjct: 1126 EEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEE--LQQEEEQL 1183
Query: 121 LAGFKREEEEK 131
L REE+EK
Sbjct: 1184 L----REEQEK 1190
Score = 39.3 bits (90), Expect = 0.004
Identities = 32/137 (23%), Positives = 63/137 (45%), Gaps = 10/137 (7%)
Query: 5 KSEQQRILR--RHQRERQELQAQIRSLKNSVPKTDKT-------KRKQLLQDVARMEAEM 55
+ E++++LR R +R RQE + Q R K K ++ +R+Q + R E E+
Sbjct: 937 QQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEEL 996
Query: 56 AQKHRQELEKFQDDSSIESVVEDLAKMN-LENRPPRSSKAHRKRERMESEERERQESIFQ 114
Q+ Q L + ++ + K + L+ + + R++ R++ ER+ +E
Sbjct: 997 QQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEEL 1056
Query: 115 AEMSEHLAGFKREEEEK 131
+ E L G +RE +
Sbjct: 1057 QQEEEQLLGEERETRRR 1073
Score = 38.9 bits (89), Expect = 0.005
Identities = 39/151 (25%), Positives = 65/151 (43%), Gaps = 22/151 (14%)
Query: 2 DDPKSEQQRILRRH---------QRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARME 52
D + E QR QR RQ+ Q Q R L +++K +R + +D R +
Sbjct: 112 DRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLE-QRDRQRRD 170
Query: 53 AEMAQKHRQELEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRK--------RERMESE 104
E+ + RQE ++ ++ + E ++ E P R+ RE + +
Sbjct: 171 EEL-WRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQ 229
Query: 105 ERERQESIFQAEMSEHLAGFK---REEEEKL 132
RERQ+ +FQ E + + R+EEEKL
Sbjct: 230 RRERQDRVFQEEEEKEWRKRETVLRKEEEKL 260
Score = 38.9 bits (89), Expect = 0.005
Identities = 27/118 (22%), Positives = 55/118 (46%), Gaps = 12/118 (10%)
Query: 14 RHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQELEKFQDDSSIE 73
+ QRE QE + Q+R L+ + ++ + +Q Q + R E ++ +K +E + Q++
Sbjct: 266 QRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRR-EQQLRRKQEEERREQQEE---- 320
Query: 74 SVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSEHLAGFKREEEEK 131
+ + R + + ++ R E EER Q+ + E +RE+EE+
Sbjct: 321 -------RREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEE 371
Score = 38.9 bits (89), Expect = 0.005
Identities = 29/130 (22%), Positives = 65/130 (50%), Gaps = 8/130 (6%)
Query: 2 DDPKSEQQRILRRHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQ 61
++ + EQQ RR Q+ER+E Q + R + + + + +R+Q L R E E ++ Q
Sbjct: 311 EEERREQQEE-RREQQERREQQEERR--EQQLRREQEERREQQL----RREQE-EERREQ 362
Query: 62 ELEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSEHL 121
+L + Q++ E + ++ E + R + R+++ ++ R++ + + +
Sbjct: 363 QLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 422
Query: 122 AGFKREEEEK 131
+RE+EE+
Sbjct: 423 QQLRREQEEE 432
Score = 38.5 bits (88), Expect = 0.007
Identities = 24/131 (18%), Positives = 65/131 (49%), Gaps = 7/131 (5%)
Query: 5 KSEQQRILRRHQ-RERQELQAQIRSLKNSVPKTDKTKRKQLLQD---VARMEAEMAQKHR 60
+ Q R+ + + +E ++ + +R + + + + ++++L ++ + ++E + ++ R
Sbjct: 231 RERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRER 290
Query: 61 QELEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSEH 120
QE E+ Q E + L + E R + + ++ER E +E R++ + + +
Sbjct: 291 QEEEQQQQRLRRE---QQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERR 347
Query: 121 LAGFKREEEEK 131
+RE+EE+
Sbjct: 348 EQQLRREQEEE 358
Score = 38.5 bits (88), Expect = 0.007
Identities = 31/111 (27%), Positives = 58/111 (52%), Gaps = 21/111 (18%)
Query: 2 DDPKSEQQRILR--RHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKH 59
++ + E++++LR R +R RQEL+ Q R + + + +QLL++ E ++
Sbjct: 1114 EELQQEEEQLLREEREKRRRQELERQYREEEEV-----QQEEEQLLRE------EPEKRR 1162
Query: 60 RQELEK-FQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQ 109
RQELE+ ++++ ++ E L + E R ++RER EE E Q
Sbjct: 1163 RQELERQYREEEELQQEEEQLLREEQEKR-------RQERERQYREEEELQ 1206
Score = 38.1 bits (87), Expect = 0.009
Identities = 43/147 (29%), Positives = 70/147 (47%), Gaps = 29/147 (19%)
Query: 5 KSEQQRILRRHQRERQE-----------LQAQIRSLKNSVPKTDKTKRKQLL--QDVARM 51
+ EQQ LRR Q ER+E LQ ++RS + + + + +R+QLL ++ R+
Sbjct: 502 RREQQ--LRREQEERREQRLKRQEEEERLQQRLRS-EQQLRREQEERREQLLKREEEKRL 558
Query: 52 EAEMAQKHRQELEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKR--ERMESEERERQ 109
E E + Q L++ Q++ + L K E R R + +R +R++ EE ER
Sbjct: 559 EQE---RREQRLKREQEERR-----DQLLKREEERRQQRLKREQEERLEQRLKREEVERL 610
Query: 110 ESIFQAEMSEHLAGFKREEEEKLAAIL 136
E Q E E + EEE+ +L
Sbjct: 611 E---QEERREQRLKREEPEEERRQQLL 634
Score = 37.7 bits (86), Expect = 0.012
Identities = 27/107 (25%), Positives = 49/107 (45%), Gaps = 6/107 (5%)
Query: 5 KSEQQRILRRHQ--RERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQE 62
+ EQ R L R + RERQE + Q + L+ + + +RKQ + + E Q+ R+E
Sbjct: 274 EEEQLRKLERQELRRERQEEEQQQQRLR----REQQLRRKQEEERREQQEERREQQERRE 329
Query: 63 LEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQ 109
++ + + + E+ + L + + R E E RE+Q
Sbjct: 330 QQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQ 376
Score = 37.7 bits (86), Expect = 0.012
Identities = 33/138 (23%), Positives = 65/138 (47%), Gaps = 13/138 (9%)
Query: 5 KSEQQRILRRHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQELE 64
+ EQQ LRR Q E + Q + + K ++ +R+ L+ E ++ +Q+L+
Sbjct: 420 RREQQ--LRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLK 477
Query: 65 KFQDDSSIE---SVVEDLAKMNLENRPP--RSSKAHRKRERME-SEERERQESIFQAEMS 118
+ Q++ E + E+ + E R R + R+ +R++ EE ER + ++E
Sbjct: 478 RDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQ 537
Query: 119 EHLAGFKREEEEKLAAIL 136
+RE+EE+ +L
Sbjct: 538 -----LRREQEERREQLL 550
Score = 37.7 bits (86), Expect = 0.012
Identities = 29/135 (21%), Positives = 66/135 (48%), Gaps = 15/135 (11%)
Query: 2 DDPKSEQQRILRRHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQ 61
++P+ +++ L R RE +ELQ + + + + ++ KR+Q + R E E+ ++ R+
Sbjct: 1156 EEPEKRRRQELERQYREEEELQQE----EEQLLREEQEKRRQERERQYREEEELQRQKRK 1211
Query: 62 ELEKFQDDSS-----IESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAE 116
+ + +D S E E+ + N R ++ R+ E + +R+ Q+ +
Sbjct: 1212 QRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDL---- 1267
Query: 117 MSEHLAGFKREEEEK 131
+HL G ++E + +
Sbjct: 1268 --QHLLGEQQERDRE 1280
Score = 37.4 bits (85), Expect = 0.015
Identities = 30/130 (23%), Positives = 65/130 (50%), Gaps = 8/130 (6%)
Query: 2 DDPKSEQQRILRRHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQ 61
++ + EQQ LRR Q E + Q Q+R + + + + +R+Q L+ ++ E + Q
Sbjct: 356 EEERREQQ--LRREQEEERREQ-QLRR-EQQLRREQQLRREQQLRREQQLRREQQLRREQ 411
Query: 62 ELEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSEHL 121
+L + Q + L + E R + + R+ +R++ E+ ER++ + + E +E
Sbjct: 412 QLRREQQLRR----EQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERH 467
Query: 122 AGFKREEEEK 131
+R+++ K
Sbjct: 468 EQERRKQQLK 477
Score = 36.6 bits (83), Expect = 0.026
Identities = 33/133 (24%), Positives = 61/133 (45%), Gaps = 8/133 (6%)
Query: 2 DDPKSEQQRILRRHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQ 61
++ + EQQ LRR Q+ R+E Q + + + + + +R+Q L+ ++ E + Q
Sbjct: 369 EEERREQQ--LRREQQLRREQQLR---REQQLRREQQLRREQQLRREQQLRREQQLRREQ 423
Query: 62 ELEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRER-MESEERERQESIFQAEMSEH 120
+L + Q++ E E + R + KRE E E+ER++ + + E
Sbjct: 424 QLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEE 483
Query: 121 L--AGFKREEEEK 131
K EEEE+
Sbjct: 484 RRERWLKLEEEER 496
Score = 35.8 bits (81), Expect = 0.045
Identities = 43/174 (24%), Positives = 76/174 (43%), Gaps = 15/174 (8%)
Query: 7 EQQRILRR---HQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQEL 63
E++++L+ Q RQE + R + + + ++ +RK L ++ E+ +K R+E
Sbjct: 1671 EEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQER-ERKFLQEEQQLRRQELERKFREEE 1729
Query: 64 EKFQDDSSIESVVEDLAKMNLEN---RPPRSSKAHRKRER---MESEERERQESIFQAEM 117
+ Q+ + ++ + LE RP R + R++ER EE+ RQE Q
Sbjct: 1730 QLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLR 1789
Query: 118 SEHLAGFKREEEEKLAAILGARGLEMKAIPADGHCMYRAIQDQLVFSVSVEMLR 171
S+ REEE+ L E + P YR ++QL + LR
Sbjct: 1790 SQESDRKFREEEQ-----LRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLR 1838
Score = 35.0 bits (79), Expect = 0.076
Identities = 32/125 (25%), Positives = 56/125 (44%), Gaps = 19/125 (15%)
Query: 7 EQQRILRRHQRERQELQA--QIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQELE 64
E+++ L R QR+R+ LQ Q+R + + RK ++ R E E Q RQE +
Sbjct: 1519 EEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERD 1578
Query: 65 KFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSEHLAGF 124
+ K LE + R + ++R+ ME E++ R++ Q E F
Sbjct: 1579 R---------------KFRLEEQKVR--RQEQERKFMEDEQQLRRQEGQQQLRQERDRKF 1621
Query: 125 KREEE 129
+ +E+
Sbjct: 1622 REDEQ 1626
Score = 33.9 bits (76), Expect = 0.17
Identities = 39/166 (23%), Positives = 69/166 (41%), Gaps = 44/166 (26%)
Query: 8 QQRILRRHQRERQEL------QAQIRS-LKNSVPK------------------------- 35
+QR+ R H+ ER+E Q Q R +K+ +PK
Sbjct: 669 EQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEG 728
Query: 36 -----TDKTKRKQLLQDVARMEAEMAQKHRQELEKFQDDSSIESVVE--DLAKMNLENRP 88
+ KR++ ++ E E A + +QE E+ +D + E + + L RP
Sbjct: 729 QRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARP 788
Query: 89 PRSSKAHRKRERMESEERERQESIF--QAEMSEHLAGFKREEEEKL 132
P + R ++ +EER+++E F + E E +RE E++L
Sbjct: 789 PLREQRER---QLRAEERQQREQRFLPEEEEKEQRRRQRREREKEL 831
Score = 32.7 bits (73), Expect = 0.38
Identities = 28/139 (20%), Positives = 62/139 (44%), Gaps = 9/139 (6%)
Query: 2 DDPKSEQQRILRRHQRERQELQAQI--RSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKH 59
++ + EQ+R +R +RE++E + Q+ R + + + + ++L Q + R E E ++
Sbjct: 554 EEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQE 613
Query: 60 RQELEKFQDDSSIESVVEDLAKMNLEN-------RPPRSSKAHRKRERMESEERERQESI 112
+ ++ + + E + L K + R + + ++ +R E EER Q
Sbjct: 614 ERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLK 673
Query: 113 FQAEMSEHLAGFKREEEEK 131
+ E EE+E+
Sbjct: 674 REHEEERREQELAEEEQEQ 692
Score = 32.0 bits (71), Expect = 0.65
Identities = 25/131 (19%), Positives = 59/131 (45%), Gaps = 9/131 (6%)
Query: 5 KSEQQRILRRHQRERQE-----LQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKH 59
K E+Q + R Q E Q+ + Q+R + + + +R++ Q R + E ++
Sbjct: 280 KLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERRE--QQERREQQE--ERR 335
Query: 60 RQELEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSE 119
Q+L + Q++ + + + + E + R + R+ +++ E++ R+E + E
Sbjct: 336 EQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQL 395
Query: 120 HLAGFKREEEE 130
R E++
Sbjct: 396 RREQQLRREQQ 406
Score = 32.0 bits (71), Expect = 0.65
Identities = 31/139 (22%), Positives = 69/139 (49%), Gaps = 17/139 (12%)
Query: 2 DDPKSEQQRILRRHQRERQELQAQIRSLKNSV---PKTDKTKRK--QLLQDVAR--MEAE 54
+D + + + RR Q+ R +L+ + + ++++ P + RK QLLQ+ E
Sbjct: 858 EDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREE 917
Query: 55 MAQKHRQELEK-FQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRE-RMESEERERQESI 112
++ RQE E+ ++++ ++ E L + E R + R+R+ R + + ++++E +
Sbjct: 918 REKRRRQEQERQYREEEQLQQEEEQLLREEREKR----RRQERERQYRKDKKLQQKEEQL 973
Query: 113 FQAEMSEHLAGFKREEEEK 131
E + +R+E EK
Sbjct: 974 LGEEPEKR----RRQEREK 988
Score = 31.6 bits (70), Expect = 0.84
Identities = 24/113 (21%), Positives = 56/113 (49%), Gaps = 11/113 (9%)
Query: 5 KSEQQRILRRHQRERQEL--QAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQE 62
+ +++R+ +R +RE E Q + R + + ++ +R+QLL+ E ++ +Q+
Sbjct: 592 REQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKS-----EEQEERRQQQ 646
Query: 63 LEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERM----ESEERERQES 111
L + Q + + + + + LE R R + R+ + + + + RER +S
Sbjct: 647 LRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKS 699
Score = 31.2 bits (69), Expect = 1.1
Identities = 30/136 (22%), Positives = 63/136 (46%), Gaps = 20/136 (14%)
Query: 7 EQQRILRRHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQELEK- 65
E+++ +RR +RER+ L+ + + + K + +QLLQ E E Q HRQE ++
Sbjct: 1434 EEEQQVRRQERERKFLEEEQQLRQERHRKF--REEEQLLQ-----EREEQQLHRQERDRK 1486
Query: 66 -FQDDSSIESVVED--LAKMNLENRPPRSS---------KAHRKRERMESEERERQESIF 113
+++ + D + L ++ P + R+R+ ++ E++ R++
Sbjct: 1487 FLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERG 1546
Query: 114 QAEMSEHLAGFKREEE 129
Q + F+ EE+
Sbjct: 1547 QQRRQDRDRKFREEEQ 1562
Score = 31.2 bits (69), Expect = 1.1
Identities = 36/136 (26%), Positives = 59/136 (43%), Gaps = 13/136 (9%)
Query: 5 KSEQQRILRRHQRERQ--ELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQE 62
+ EQQ L R +R+R+ E + Q+R + RK ++ E E Q RQE
Sbjct: 1631 REEQQ--LHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQE 1688
Query: 63 LE-KFQDDSSIESVVEDLAKMNLENRPPRSSKAHRK-------RERMESEERERQESIFQ 114
+ KF+++ E K E + R + RK R+ E E+ RQE ++
Sbjct: 1689 RDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQER-YR 1747
Query: 115 AEMSEHLAGFKREEEE 130
+ E +REE++
Sbjct: 1748 KILEEEQLRPEREEQQ 1763
Score = 30.8 bits (68), Expect = 1.4
Identities = 22/132 (16%), Positives = 62/132 (46%), Gaps = 7/132 (5%)
Query: 5 KSEQQRILRRHQRERQELQAQIRSLKNS---VPKTDKTKRKQLLQDVARMEAEMAQKHRQ 61
+ +++ LRR +R+R+ + ++R + + + + +R++ + + E ++ + R+
Sbjct: 1346 QEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQERE 1405
Query: 62 ELEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRER----MESEERERQESIFQAEM 117
+ + D + L++ + + + R++ER +E E++ RQE +
Sbjct: 1406 QQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFRE 1465
Query: 118 SEHLAGFKREEE 129
E L + E++
Sbjct: 1466 EEQLLQEREEQQ 1477
Score = 29.6 bits (65), Expect = 3.2
Identities = 30/127 (23%), Positives = 53/127 (41%), Gaps = 11/127 (8%)
Query: 7 EQQRILRRHQ-RERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQELEK 65
E+Q++ R+ Q R+ E + Q+R + + RK + E E Q HRQE ++
Sbjct: 1584 EEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDR 1643
Query: 66 FQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSEHLAGFK 125
+E+ ++ + R H + + EE+ QE Q +
Sbjct: 1644 --------KFLEEEPQLRRQER--EQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKF 1693
Query: 126 REEEEKL 132
REEE++L
Sbjct: 1694 REEEQQL 1700
Score = 28.5 bits (62), Expect = 7.2
Identities = 31/134 (23%), Positives = 62/134 (46%), Gaps = 12/134 (8%)
Query: 7 EQQRILRRHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQELE-- 64
E+++ RR QR +E + Q + + + ++ ++ Q +D + + E + Q +
Sbjct: 814 EEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQK 873
Query: 65 -KFQDDSSIESVVEDL-AKMNLENRPPRSSKA-HRKRERMESEERE---RQESIFQAEMS 118
++Q + + L AK L+ + + + + E ++ EERE RQE Q
Sbjct: 874 WRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREE 933
Query: 119 EHLAGFKREEEEKL 132
E L ++EEE+L
Sbjct: 934 EQL----QQEEEQL 943
Score = 28.1 bits (61), Expect = 9.3
Identities = 22/92 (23%), Positives = 42/92 (45%), Gaps = 2/92 (2%)
Query: 50 RMEAEMAQKHRQELEKFQDD-SSIESVVEDLAKMNLENRPPRSSKAHRKRER-MESEERE 107
++E E Q+ RQ+ ++ + + + E E ++ +R R + R+R+ E EER
Sbjct: 128 QLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERR 187
Query: 108 RQESIFQAEMSEHLAGFKREEEEKLAAILGAR 139
+E Q+ F EE+ + +L R
Sbjct: 188 AEEEQLQSCKGHETEEFPDEEQLRRRELLELR 219
>gi|4505101 microtubule-associated protein 7 [Homo sapiens]
Length = 749
Score = 43.9 bits (102), Expect = 2e-04
Identities = 34/123 (27%), Positives = 60/123 (48%), Gaps = 9/123 (7%)
Query: 7 EQQRILRRHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQELEKF 66
EQ+ R +RE++EL+ Q R ++T R++ ++ R+EAE A++ ++L++
Sbjct: 492 EQREKEERERREQEELERQKREELAQRVAEERTTRRE--EESRRLEAEQAREKEEQLQRQ 549
Query: 67 QDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSEHLAGFKR 126
++ ++ + E + + R RE E +ER E FQ E E L KR
Sbjct: 550 AEERALRE------REEAERAQRQKEEEARVREEAERVRQER-EKHFQREEQERLERKKR 602
Query: 127 EEE 129
EE
Sbjct: 603 LEE 605
Score = 42.4 bits (98), Expect = 5e-04
Identities = 33/125 (26%), Positives = 58/125 (46%), Gaps = 12/125 (9%)
Query: 8 QQRILRRHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQELEKFQ 67
++R L R QRE++E + + + ++ KR++L Q VA ++ + LE Q
Sbjct: 485 EKRRLAREQREKEERE------RREQEELERQKREELAQRVAEERTTRREEESRRLEAEQ 538
Query: 68 DDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSEHLAGFKRE 127
E + + L R +A R + + E E R R+E+ + E F+RE
Sbjct: 539 AREKEEQLQRQAEERALRER----EEAERAQRQKEEEARVREEA--ERVRQEREKHFQRE 592
Query: 128 EEEKL 132
E+E+L
Sbjct: 593 EQERL 597
Score = 38.9 bits (89), Expect = 0.005
Identities = 29/104 (27%), Positives = 50/104 (48%), Gaps = 6/104 (5%)
Query: 28 SLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQELEKFQDDSSIESVVEDLAKMNLENR 87
S+K S TD + +LL + R+ E Q+ ++E E+ + + E+LA+ E R
Sbjct: 466 SVKTSAGTTDPEEATRLLAEKRRLARE--QREKEERERREQEELERQKREELAQRVAEER 523
Query: 88 PPRSSKAHRKRERMESEERERQESIFQAEMSEHLAGFKREEEEK 131
R + R+ E ++ E+E Q +E A +REE E+
Sbjct: 524 TTRREEESRRLEAEQAREKEEQ----LQRQAEERALREREEAER 563
>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
Length = 2115
Score = 43.5 bits (101), Expect = 2e-04
Identities = 33/144 (22%), Positives = 68/144 (47%), Gaps = 2/144 (1%)
Query: 2 DDPKSEQQRILRRHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQ 61
++ + Q + + QRE+ EL ++ L+ V +T + ++ + VA +E ++ + ++
Sbjct: 628 NEARDSAQTSVTQAQREKAELSRKVEELQACV-ETARQEQHEAQAQVAELELQLRSEQQK 686
Query: 62 ELEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMES-EERERQESIFQAEMSEH 120
EK + + + E L + + + S KR ++ EE++R S +AE
Sbjct: 687 ATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSL 746
Query: 121 LAGFKREEEEKLAAILGARGLEMK 144
+ KRE +E G +GLE +
Sbjct: 747 VEQHKRERKELEEERAGRKGLEAR 770
Score = 35.4 bits (80), Expect = 0.058
Identities = 44/193 (22%), Positives = 81/193 (41%), Gaps = 38/193 (19%)
Query: 13 RRHQRERQELQAQIRSLK--------------------NSVPKTDKTKRK-------QLL 45
+R Q ERQ+L AQ+ L+ + K + K K +
Sbjct: 1524 QRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQ 1583
Query: 46 QDVARMEAEMAQKHRQELEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEE 105
Q+ R++A++ + Q +K Q + +E AK + + + ++ + + +E +
Sbjct: 1584 QEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEK-AKTHYDAKKQQNQELQEQLRSLEQLQ 1642
Query: 106 RERQESIFQAEMSEH---LAGFKREEEEKLAAILGA--RGLEMKAIPADGHCMYRAIQDQ 160
+E +E +AE H AG K +E E+ L A R LE + AD + ++D
Sbjct: 1643 KENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHAD-----QQLRDL 1697
Query: 161 LVFSVSVEMLRCR 173
F V+ + L+ R
Sbjct: 1698 GKFQVATDALKSR 1710
Score = 33.1 bits (74), Expect = 0.29
Identities = 31/141 (21%), Positives = 66/141 (46%), Gaps = 11/141 (7%)
Query: 3 DPKSEQQRILRRHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQE 62
+ +++ + L++ ++ Q L+ Q+ L +S+ + ++Q L++VA + Q H Q+
Sbjct: 530 EKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQ-----KEQQLKEVAEKQEATRQDHAQQ 584
Query: 63 LEKFQDDSSIESVVEDLAKMNLEN-RPPRSSKAHRKRERMESEERER---QESIFQAEMS 118
L ++ D A LE +++K +++++ R Q S+ QA+
Sbjct: 585 LATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQRE 644
Query: 119 EHLAGFKREEEEKLAAILGAR 139
+ A R+ EE A + AR
Sbjct: 645 K--AELSRKVEELQACVETAR 663
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 43.1 bits (100), Expect = 3e-04
Identities = 41/158 (25%), Positives = 71/158 (44%), Gaps = 16/158 (10%)
Query: 5 KSEQQRIL---RRHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDV-ARMEAEMAQKHR 60
+ E R+L RR RE++E + Q R L+ K + + +QL ++ AR E E + R
Sbjct: 596 REEATRLLAEKRRQAREQREREEQERRLQAERDK--RMREEQLAREAEARAEREAEARRR 653
Query: 61 QELEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKR----------ERMESEERERQE 110
+E E + + + E L K E +A R+R E+ E R+R E
Sbjct: 654 EEQEAREKAQAEQEEQERLQKQKEEAEARSREEAERQRLEREKHFQQQEQERQERRKRLE 713
Query: 111 SIFQAEMSEHLAGFKREEEEKLAAILGARGLEMKAIPA 148
I + ++ K++++ K A G+ +KA+ A
Sbjct: 714 EIMKRTRKSEVSETKQKQDSKEANANGSSPEPVKAVEA 751
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 42.0 bits (97), Expect = 6e-04
Identities = 37/137 (27%), Positives = 68/137 (49%), Gaps = 12/137 (8%)
Query: 12 LRRHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQELEKFQD-DS 70
LRR +++RQEL+ R L+ D T L +A ++A++A+ Q +K ++ +
Sbjct: 1036 LRREEKQRQELEKTRRKLEG-----DST---DLSDQIAELQAQIAELKMQLAKKEEELQA 1087
Query: 71 SIESVVEDLAKMNLENRPPR--SSKAHRKRERMESEERERQESIFQ-AEMSEHLAGFKRE 127
++ V E+ A+ N+ + R S+ +E +ESE R ++ Q ++ E L K E
Sbjct: 1088 ALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTE 1147
Query: 128 EEEKLAAILGARGLEMK 144
E+ L + + L K
Sbjct: 1148 LEDTLDSTAAQQELRSK 1164
Score = 40.4 bits (93), Expect = 0.002
Identities = 37/113 (32%), Positives = 59/113 (52%), Gaps = 14/113 (12%)
Query: 21 ELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQELEKFQD-DSSIESVVEDL 79
ELQAQI LK + K K ++L +AR+E E AQK+ L+K ++ +S I + EDL
Sbjct: 1066 ELQAQIAELKMQLAK----KEEELQAALARVEEEAAQKN-MALKKIRELESQISELQEDL 1120
Query: 80 AKMNLENRPPRSSKAHRKR---ERMESEERERQESIFQAEMSEHLAGFKREEE 129
R R+ +KR E +E+ + E ++++ + L KRE+E
Sbjct: 1121 E----SERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRS-KREQE 1168
Score = 36.2 bits (82), Expect = 0.034
Identities = 32/150 (21%), Positives = 73/150 (48%), Gaps = 15/150 (10%)
Query: 3 DPKSEQQRILRRHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQE 62
+ K+E +R+ ++ + E ++L + + SV + +K+KR L Q V M+ ++ ++ E
Sbjct: 1490 EQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKR-ALEQQVEEMKTQL-EELEDE 1547
Query: 63 LEKFQDDSSIESVVEDLAKMNLE-NRPPRSSKAHRKRERMESEERERQESIFQAEMSEHL 121
L+ +D AK+ LE N ++ R + + + E+++ + + ++ E
Sbjct: 1548 LQATED-----------AKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVR-QVREME 1595
Query: 122 AGFKREEEEKLAAILGARGLEMKAIPADGH 151
A + E +++ A+ + LEM + H
Sbjct: 1596 AELEDERKQRSMAVAARKKLEMDLKDLEAH 1625
Score = 34.7 bits (78), Expect = 0.100
Identities = 23/117 (19%), Positives = 57/117 (48%), Gaps = 2/117 (1%)
Query: 20 QELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQELEKFQDDSSIESVVEDL 79
Q ++AQ + + K+KQL++ V MEAE+ + +Q +E ++DL
Sbjct: 1563 QAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDL 1622
Query: 80 AKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMS-EHLAGFKREEEEKLAAI 135
+ ++++ +A ++ +++++ ++ + S E + +E E+KL ++
Sbjct: 1623 -EAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSM 1678
Score = 33.1 bits (74), Expect = 0.29
Identities = 30/134 (22%), Positives = 64/134 (47%), Gaps = 12/134 (8%)
Query: 2 DDPKSEQQRILRRHQRERQ-ELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHR 60
D+ E+++ L R RE + EL+ + + +V RK+L D+ +EA + ++
Sbjct: 1577 DEQSEEKKKQLVRQVREMEAELEDERKQRSMAV-----AARKKLEMDLKDLEAHIDSANK 1631
Query: 61 QELEKFQDDSSIESVVEDLAKMNLENRPPR------SSKAHRKRERMESEERERQESIFQ 114
E + +++ ++D + + R R + + +K + ME+E + QE +
Sbjct: 1632 NRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAA 1691
Query: 115 AEMSEHLAGFKREE 128
AE ++ A +R+E
Sbjct: 1692 AERAKRQAQQERDE 1705
Score = 32.7 bits (73), Expect = 0.38
Identities = 26/143 (18%), Positives = 66/143 (46%), Gaps = 9/143 (6%)
Query: 1 MDDPKSEQQRILRRHQRERQELQAQIRSLKNSV-----PKTDKTKRKQLLQD-VARMEAE 54
+++ E++ ++ Q E+ +A+++ L+ K K+LL+D +A
Sbjct: 948 LEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTN 1007
Query: 55 MAQKHRQELEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESI-- 112
+ ++ + + + E+++ DL + L + + + R ++E + + + I
Sbjct: 1008 LTEEEEKSKSLAKLKNKHEAMITDLEE-RLRREEKQRQELEKTRRKLEGDSTDLSDQIAE 1066
Query: 113 FQAEMSEHLAGFKREEEEKLAAI 135
QA+++E ++EEE AA+
Sbjct: 1067 LQAQIAELKMQLAKKEEELQAAL 1089
Score = 30.0 bits (66), Expect = 2.5
Identities = 25/119 (21%), Positives = 57/119 (47%), Gaps = 13/119 (10%)
Query: 13 RRHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQ---------KHRQEL 63
++++ RQ+L+ Q + LK + + + T + + + +EA++AQ K RQ
Sbjct: 1774 QKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAA 1833
Query: 64 EK--FQDDSSIESVV--EDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMS 118
K + + ++ V+ D + N E ++ KA + ++++ + E +E +A S
Sbjct: 1834 CKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANAS 1892
Score = 28.5 bits (62), Expect = 7.2
Identities = 34/180 (18%), Positives = 73/180 (40%), Gaps = 19/180 (10%)
Query: 17 RERQELQAQIRSLKNSVPKTDKTKRKQL-----LQDVARMEAEMAQKHRQELEKFQDDSS 71
R+ +E+ A+ L K + KQL L ++ +++++ + Q E+ Q ++
Sbjct: 842 RQEEEMMAKEEELV-------KVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETE 894
Query: 72 IESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSEHLAGFKREEEEK 131
+ + E+L + H R+E EE Q QAE + + EE+
Sbjct: 895 LCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQH--LQAEKKKMQQNIQELEEQL 952
Query: 132 LAAILGARGLEMKAIPADGHCMYRAIQDQLVFSVSVEMLRCRTASYMKKHVDEFLPFFSN 191
+ L+++ + + + + ++Q++ +E C+ A K D F +N
Sbjct: 953 EEEESARQKLQLEKVTTEAK-LKKLEEEQII----LEDQNCKLAKEKKLLEDRIAEFTTN 1007
>gi|92859701 myosin VI [Homo sapiens]
Length = 1285
Score = 42.0 bits (97), Expect = 6e-04
Identities = 43/175 (24%), Positives = 76/175 (43%), Gaps = 20/175 (11%)
Query: 19 RQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQELEKF----QDDSSIES 74
++E A ++S + + K K+++ EAE ++ ++E+EK ++D
Sbjct: 896 QKEYDALVKSSEELLSALQKKKQQE-------EEAERLRRIQEEMEKERKRREEDEKRRR 948
Query: 75 VVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSEHLAGFKREEEEKLAA 134
E+ +M LE +A RK+E E ++RE E QAE+ LA K EE ++ A
Sbjct: 949 KEEEERRMKLE------MEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKEEESQQQAV 1002
Query: 135 I---LGARGLEMKAIPADGHCMYRAIQDQLVFSVSVEMLRCRTASYMKKHVDEFL 186
+ R L ++ ++ + Q L + T M K + EFL
Sbjct: 1003 LEQERRDRELALRIAQSEAELISDEAQADLALRRNDGTRPKMTPEQMAKEMSEFL 1057
Score = 28.9 bits (63), Expect = 5.5
Identities = 21/76 (27%), Positives = 40/76 (52%), Gaps = 4/76 (5%)
Query: 7 EQQRILRRHQRERQELQAQIRSLKNSVP---KTDKTKRKQLLQDVARMEAEM-AQKHRQE 62
E++R R +R+ + + R +K + K ++ +RK+ D R++AE+ AQ RQ+
Sbjct: 934 EKERKRREEDEKRRRKEEEERRMKLEMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQK 993
Query: 63 LEKFQDDSSIESVVED 78
E+ Q + +E D
Sbjct: 994 EEESQQQAVLEQERRD 1009
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 41.6 bits (96), Expect = 8e-04
Identities = 29/128 (22%), Positives = 61/128 (47%), Gaps = 1/128 (0%)
Query: 5 KSEQQRILRRHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQELE 64
K ++R R+ +RE++ + + + K K ++ +RK+ ++ E E +K +++ +
Sbjct: 61 KERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEK 120
Query: 65 KFQDDSSIESVV-EDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSEHLAG 123
K + +S E E + E R R K + + E +ER+++E E E
Sbjct: 121 KERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKE 180
Query: 124 FKREEEEK 131
+R+E +K
Sbjct: 181 KERKERKK 188
Score = 38.9 bits (89), Expect = 0.005
Identities = 28/129 (21%), Positives = 61/129 (47%), Gaps = 3/129 (2%)
Query: 5 KSEQQRILRRHQRERQELQAQIRSLKNSVPKTDKTKR--KQLLQDVARMEAEMAQKHRQE 62
K E++R RR ++E +E + + + K + +T + K+ + R E ++ R++
Sbjct: 92 KEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKK 151
Query: 63 LEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSEHLA 122
E+ ++ E + ++ E R K ++R++ E +ER++ + E E
Sbjct: 152 EEREKERERKERKKRERKQVG-EKEEERKEKERKERKKRERNRKERKKERERKERRERKK 210
Query: 123 GFKREEEEK 131
K++EE K
Sbjct: 211 ERKKKEERK 219
Score = 35.4 bits (80), Expect = 0.058
Identities = 27/125 (21%), Positives = 52/125 (41%), Gaps = 21/125 (16%)
Query: 7 EQQRILRRHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQELEKF 66
E++ +R +R+ +E + + R + + K +RKQ V E E +K R+E +K
Sbjct: 134 ERKEERKREERKERERKKEEREKERERKERKKRERKQ----VGEKEEERKEKERKERKKR 189
Query: 67 QDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSEHLAGFKR 126
+ NR R + RK R +ER+++E + + ++
Sbjct: 190 E-----------------RNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWRE 232
Query: 127 EEEEK 131
+E K
Sbjct: 233 KERGK 237
Score = 33.5 bits (75), Expect = 0.22
Identities = 23/127 (18%), Positives = 62/127 (48%), Gaps = 5/127 (3%)
Query: 7 EQQRILRRHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARME--AEMAQKHRQELE 64
E++R + + ++E +++ + + K + + K+ ++ + E E ++ R+ +
Sbjct: 40 EREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKK 99
Query: 65 KFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSEHLAGF 124
+ ++ + E ++ K + R+SK ++RER E +RE ++ + E +
Sbjct: 100 RRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERK---ERERKKEEREK 156
Query: 125 KREEEEK 131
+RE +E+
Sbjct: 157 ERERKER 163
Score = 30.8 bits (68), Expect = 1.4
Identities = 30/120 (25%), Positives = 51/120 (42%), Gaps = 7/120 (5%)
Query: 17 RERQ-ELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQELEKFQDDSSIESV 75
RER+ E++ + K + K +R++ + R + ++ ++E + + E
Sbjct: 39 REREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERK 98
Query: 76 VEDLAKMNLENRPPRSSKAHRKRER----MESEERERQESIFQAEMSEHLAGFKREEEEK 131
K N E K K+ER E +ERER+E + E E K+EE EK
Sbjct: 99 KRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERER--KKEEREK 156
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 41.6 bits (96), Expect = 8e-04
Identities = 32/140 (22%), Positives = 65/140 (46%), Gaps = 10/140 (7%)
Query: 2 DDPKSEQQRILRRHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQ 61
++ + Q +L++ + E QE + K + ++ +R+Q ++ R E E ++ R+
Sbjct: 654 EEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERR 713
Query: 62 ELEKFQDDSSIESVVEDL-AKMNLENRPP--RSSKAHRKRERMESEERERQESIFQAEMS 118
E E+ + E L A+ L+ R R K +RE E +++E Q+ + + ++
Sbjct: 714 EQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQ 773
Query: 119 EHLAGFKREEEEKLAAILGA 138
E E+E+K GA
Sbjct: 774 E-------EQEKKAKEAAGA 786
Score = 40.0 bits (92), Expect = 0.002
Identities = 36/132 (27%), Positives = 64/132 (48%), Gaps = 21/132 (15%)
Query: 12 LRRHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARME--AEMAQKHRQELEKFQDD 69
L+R +R R+ LQA+ R V + + K+KQ+ Q A+++ E A++ R EK +
Sbjct: 572 LKREERLRKVLQARER-----VEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKK 626
Query: 70 SSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSEHLAGFKREEE 129
++ + + E +E R + +A R R + EE R + + Q + K EE+
Sbjct: 627 AAAKKMEE------VEARRKQEEEARRLRWLQQEEEERRHQELLQKK--------KEEEQ 672
Query: 130 EKLAAILGARGL 141
E+L A+ L
Sbjct: 673 ERLRKAAEAKRL 684
Score = 36.2 bits (82), Expect = 0.034
Identities = 30/154 (19%), Positives = 69/154 (44%), Gaps = 21/154 (13%)
Query: 1 MDDPKSEQQRILRRHQRERQELQAQIRSLKNSVP--------KTDKTKRKQLLQDVARME 52
+++ K +++ LR+ + R+ ++ K + KT+K K ++L ++ A+ +
Sbjct: 567 LEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKK 626
Query: 53 AEMAQKHRQELEKFQDDSS-----IESVVEDLAKMNL--------ENRPPRSSKAHRKRE 99
A + E + Q++ + ++ E+ L + R ++++A R E
Sbjct: 627 AAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAE 686
Query: 100 RMESEERERQESIFQAEMSEHLAGFKREEEEKLA 133
+ E E RE++ + E +RE+E +LA
Sbjct: 687 QREQERREQERREQERREQERREQERREQERQLA 720
Score = 36.2 bits (82), Expect = 0.034
Identities = 37/147 (25%), Positives = 66/147 (44%), Gaps = 16/147 (10%)
Query: 7 EQQRILRRHQR--ERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQELE 64
+Q+ RRHQ ++++ + Q R K + K +R+Q ++ R E E ++ R+E E
Sbjct: 652 QQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQE 711
Query: 65 KFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERER-QESIFQAEMSEHLAG 123
+ + + + + R + +RE E E+ R Q+ Q E+ E
Sbjct: 712 RREQERQLAE----------QERRREQERLQAERELQEREKALRLQKEQLQRELEEKK-- 759
Query: 124 FKREEEEKLAAILGARGLEMKAIPADG 150
K+EE+++LA E KA A G
Sbjct: 760 -KKEEQQRLAERQLQEEQEKKAKEAAG 785
Score = 28.1 bits (61), Expect = 9.3
Identities = 25/131 (19%), Positives = 63/131 (48%), Gaps = 8/131 (6%)
Query: 10 RILRRHQRERQELQAQIRSLKNSVPKT-DKTKRKQLLQDVAR----MEAEMAQKHRQELE 64
+I + ++ ++E A+ ++ K + K ++ + ++ ++ AR ++ E ++ QEL
Sbjct: 605 QIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELL 664
Query: 65 KFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSEHLA-G 123
+ + + E + + L + + + +RE+ E+ R++ + E LA
Sbjct: 665 QKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQE--RREQERQLAEQ 722
Query: 124 FKREEEEKLAA 134
+R E+E+L A
Sbjct: 723 ERRREQERLQA 733
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 41.6 bits (96), Expect = 8e-04
Identities = 32/140 (22%), Positives = 65/140 (46%), Gaps = 10/140 (7%)
Query: 2 DDPKSEQQRILRRHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQ 61
++ + Q +L++ + E QE + K + ++ +R+Q ++ R E E ++ R+
Sbjct: 650 EEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERR 709
Query: 62 ELEKFQDDSSIESVVEDL-AKMNLENRPP--RSSKAHRKRERMESEERERQESIFQAEMS 118
E E+ + E L A+ L+ R R K +RE E +++E Q+ + + ++
Sbjct: 710 EQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQ 769
Query: 119 EHLAGFKREEEEKLAAILGA 138
E E+E+K GA
Sbjct: 770 E-------EQEKKAKEAAGA 782
Score = 40.8 bits (94), Expect = 0.001
Identities = 40/153 (26%), Positives = 67/153 (43%), Gaps = 12/153 (7%)
Query: 1 MDDPKSEQQRI--LRR----HQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAE 54
MD + E+QR+ LRR Q RQ+++ R V + + +++LQ R+E
Sbjct: 528 MDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQM 587
Query: 55 MAQKHRQELEKFQ------DDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERER 108
+K +Q +KF + + E + E+ AK + +A RK+E R
Sbjct: 588 KEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWL 647
Query: 109 QESIFQAEMSEHLAGFKREEEEKLAAILGARGL 141
Q+ + E L K EE+E+L A+ L
Sbjct: 648 QQEEEERRHQELLQKKKEEEQERLRKAAEAKRL 680
Score = 36.2 bits (82), Expect = 0.034
Identities = 30/154 (19%), Positives = 69/154 (44%), Gaps = 21/154 (13%)
Query: 1 MDDPKSEQQRILRRHQRERQELQAQIRSLKNSVP--------KTDKTKRKQLLQDVARME 52
+++ K +++ LR+ + R+ ++ K + KT+K K ++L ++ A+ +
Sbjct: 563 LEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKK 622
Query: 53 AEMAQKHRQELEKFQDDSS-----IESVVEDLAKMNL--------ENRPPRSSKAHRKRE 99
A + E + Q++ + ++ E+ L + R ++++A R E
Sbjct: 623 AAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAE 682
Query: 100 RMESEERERQESIFQAEMSEHLAGFKREEEEKLA 133
+ E E RE++ + E +RE+E +LA
Sbjct: 683 QREQERREQERREQERREQERREQERREQERQLA 716
Score = 36.2 bits (82), Expect = 0.034
Identities = 37/147 (25%), Positives = 66/147 (44%), Gaps = 16/147 (10%)
Query: 7 EQQRILRRHQR--ERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQELE 64
+Q+ RRHQ ++++ + Q R K + K +R+Q ++ R E E ++ R+E E
Sbjct: 648 QQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQE 707
Query: 65 KFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERER-QESIFQAEMSEHLAG 123
+ + + + + R + +RE E E+ R Q+ Q E+ E
Sbjct: 708 RREQERQLAE----------QERRREQERLQAERELQEREKALRLQKEQLQRELEEKK-- 755
Query: 124 FKREEEEKLAAILGARGLEMKAIPADG 150
K+EE+++LA E KA A G
Sbjct: 756 -KKEEQQRLAERQLQEEQEKKAKEAAG 781
Score = 28.1 bits (61), Expect = 9.3
Identities = 25/131 (19%), Positives = 63/131 (48%), Gaps = 8/131 (6%)
Query: 10 RILRRHQRERQELQAQIRSLKNSVPKT-DKTKRKQLLQDVAR----MEAEMAQKHRQELE 64
+I + ++ ++E A+ ++ K + K ++ + ++ ++ AR ++ E ++ QEL
Sbjct: 601 QIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELL 660
Query: 65 KFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSEHLA-G 123
+ + + E + + L + + + +RE+ E+ R++ + E LA
Sbjct: 661 QKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQE--RREQERQLAEQ 718
Query: 124 FKREEEEKLAA 134
+R E+E+L A
Sbjct: 719 ERRREQERLQA 729
>gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial
[Homo sapiens]
Length = 213
Score = 41.2 bits (95), Expect = 0.001
Identities = 32/133 (24%), Positives = 61/133 (45%), Gaps = 5/133 (3%)
Query: 3 DPKSEQQRILRRHQRERQELQAQIRSLKNSVPK---TDKTKRKQLLQDVARMEAEMAQKH 59
D + E+QR R R+RQ + R + + TD+ ++KQ +++ R+ +K
Sbjct: 69 DREGERQRE-RERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQ 127
Query: 60 RQELEKFQDDSSIESVVEDLAKMNLEN-RPPRSSKAHRKRERMESEERERQESIFQAEMS 118
++ + Q D + E A+ E R ++ HR+RER ERER+ + E
Sbjct: 128 KEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERH 187
Query: 119 EHLAGFKREEEEK 131
+ ++ E ++
Sbjct: 188 TDMERERQRETDR 200
Score = 32.0 bits (71), Expect = 0.65
Identities = 26/127 (20%), Positives = 52/127 (40%), Gaps = 15/127 (11%)
Query: 3 DPKSEQQRILRRHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQE 62
+ K+E + R QR+R+ +N D+ + KQ ++ R + RQ
Sbjct: 36 ESKTEDRHSERDRQRDRE---------RNRERDRDREREKQTDREGERQRERERDRDRQR 86
Query: 63 LEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSEHLA 122
+ + D E+ + E R + R+ ER+ ERE+Q+ + + ++
Sbjct: 87 ETERERDKERET------DRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRET 140
Query: 123 GFKREEE 129
+RE +
Sbjct: 141 DRERERQ 147
Score = 30.0 bits (66), Expect = 2.5
Identities = 25/106 (23%), Positives = 51/106 (48%), Gaps = 5/106 (4%)
Query: 5 KSEQQRILRRHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQD-VARMEAEMAQKHRQ-E 62
K +++ + R RER++ Q ++ + + +TD+ + +Q ++ E + +HR+ E
Sbjct: 110 KQKEREMERVRDREREK-QKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERE 168
Query: 63 LEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERER 108
E+ ++ E ++E R + RKR+R ERER
Sbjct: 169 RERKRERERKRETKERERHTDMERE--RQRETDRKRDRQRESERER 212
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 41.2 bits (95), Expect = 0.001
Identities = 46/198 (23%), Positives = 81/198 (40%), Gaps = 27/198 (13%)
Query: 5 KSEQQRILRRHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVA--RMEAEMAQKHRQE 62
KSE +++L + + E++ LQ++I L+ + KT + K + + V M+ E +
Sbjct: 623 KSENEKLLTQMESEKENLQSKINHLETCL-KTQQIKSHEYNERVRTLEMDRENLSVEIRN 681
Query: 63 LEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSEHLA 122
L D S+E + LA M L+ + S + H+K E + L
Sbjct: 682 LHNVLDSKSVEVETQKLAYMELQQKAEFSDQKHQK------------EIENMCLKTSQLT 729
Query: 123 GFKREEEEKLAAILGARGLEMKAIPADGHCMYRAIQDQLVFSVSVEMLRCRTASYM--KK 180
G + E KL +L ++ D H Y +++D +L+ + AS + +
Sbjct: 730 GQVEDLEHKL-QLLSNEIMDKDRCYQDLHAEYESLRD---------LLKSKDASLVTNED 779
Query: 181 HVDEFLPFFSNPETSDSF 198
H L F P SF
Sbjct: 780 HQRSLLAFDQQPAMHHSF 797
Score = 33.1 bits (74), Expect = 0.29
Identities = 27/131 (20%), Positives = 56/131 (42%), Gaps = 16/131 (12%)
Query: 18 ERQELQAQIRSLKNSVPKTDK--TKRKQLLQDVARMEAEMAQKHRQELEKFQD------- 68
E++ L QI+ + + + DK + K LL++ + E ++ ++ + +E Q+
Sbjct: 2211 EKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNE 2270
Query: 69 -------DSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSEHL 121
D I E +E + + R R+E++E+++ + Q + SEH
Sbjct: 2271 AVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHH 2330
Query: 122 AGFKREEEEKL 132
A + E L
Sbjct: 2331 ADLLKGRVENL 2341
Score = 29.3 bits (64), Expect = 4.2
Identities = 31/135 (22%), Positives = 54/135 (40%), Gaps = 12/135 (8%)
Query: 12 LRRHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQELEKFQDDSS 71
L ++ +LQ Q L K + ++ L +M + Q + K Q+D+S
Sbjct: 839 LESQKQMNSDLQKQCEELVQI-----KGEIEENLMKAEQMHQSFVAETSQRISKLQEDTS 893
Query: 72 IESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSEHLAGFKREEEEK 131
V LEN + + +++E+E+ E QE + S HL +E +
Sbjct: 894 AHQNVVAETLSALEN---KEKELQLLNDKVETEQAEIQE----LKKSNHLLEDSLKELQL 946
Query: 132 LAAILGARGLEMKAI 146
L+ L EM +I
Sbjct: 947 LSETLSLEKKEMSSI 961
Score = 28.5 bits (62), Expect = 7.2
Identities = 35/159 (22%), Positives = 71/159 (44%), Gaps = 31/159 (19%)
Query: 1 MDDPKSEQQRILRRHQ----RERQELQAQIRSLKNSVP---------KTDKTKRKQLLQD 47
M++ K E +L+ H RE L+A+++++K + K T ++ +L+D
Sbjct: 481 MEEMKKENN-LLKSHSEQKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLRD 539
Query: 48 VAR--------MEAEMAQKHRQELEKFQDDSS---------IESVVEDLAKMNLENRPPR 90
+ + E + +LEK +D S IE + + L+K E++
Sbjct: 540 LQEKINQQENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKALL 599
Query: 91 SSKAHRKRERMESEERERQESIFQAEMSEHLAGFKREEE 129
S+ +K+E E +E + S +++E + L + E+E
Sbjct: 600 SALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESEKE 638
Score = 28.5 bits (62), Expect = 7.2
Identities = 33/137 (24%), Positives = 62/137 (45%), Gaps = 30/137 (21%)
Query: 22 LQAQIRSLKNSVPKTDKTKRKQLLQDVARMEA----------EMAQKHRQELEKFQDDSS 71
LQ+ ++L+N + T K + ++ V +M A EMAQK + E+ + +
Sbjct: 2586 LQSSYKNLENELELT-KMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKN 2644
Query: 72 ------------IESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSE 119
I+S + L ++ LEN + S ++++E E + R+E I + ++
Sbjct: 2645 RLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKVREE-IAEYQLRL 2703
Query: 120 HLAGFKREEEEKLAAIL 136
H E E+K A+L
Sbjct: 2704 H------EAEKKHQALL 2714
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 40.8 bits (94), Expect = 0.001
Identities = 43/188 (22%), Positives = 87/188 (46%), Gaps = 23/188 (12%)
Query: 5 KSEQQRI-----LRRHQRERQELQAQIRSLKNSVPKTDKTKRKQL-------LQDVARME 52
++E++R+ L + Q+E + Q+ L+ + K K K ++ LQ+ R
Sbjct: 922 ETEKERVSLLETLLQTQKELADASQQLERLRQDM-KVQKLKEQETTGILQTQLQEAQREL 980
Query: 53 AEMAQKHRQELEKFQDDSS--------IESVVEDL-AKMNLENRPPRSSKAHRKRERMES 103
E A++HR +L Q++SS ++ VEDL +++ ++ R + + + E+
Sbjct: 981 KEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRET 1040
Query: 104 EERERQESIFQAEMSEHLAGFKREEEEKLAAILGARGLEMKAIPADGHCMYRAIQDQLVF 163
+E R + + E + L E+E++L + A + + + A M A +Q
Sbjct: 1041 QEYNRIQKELEREKAS-LTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKEL 1099
Query: 164 SVSVEMLR 171
S +E+LR
Sbjct: 1100 SAQMELLR 1107
Score = 35.8 bits (81), Expect = 0.045
Identities = 40/161 (24%), Positives = 72/161 (44%), Gaps = 26/161 (16%)
Query: 12 LRRHQRERQELQAQIRSL----------------KNSVPKTDKTKRKQLLQDVARMEAEM 55
L+ +R+RQ+L Q++ L +NSV + K + + +Q V + + E+
Sbjct: 745 LQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAK-EV 803
Query: 56 AQ------KHRQELEKFQDDSSIESVVEDLAKMNLENRPP--RSSKAHRKRERMESEERE 107
Q K + E+ Q + ++ LA+ E + + AH K E+ E
Sbjct: 804 IQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWE 863
Query: 108 RQESIFQAEMSEHLAGFKREEEEKLAAILGARGLEMKAIPA 148
++ S Q E+++ L +RE+ E L L + EM+AI A
Sbjct: 864 KERSWHQQELAKALESLEREKME-LEMRLKEQQTEMEAIQA 903
Score = 33.1 bits (74), Expect = 0.29
Identities = 24/115 (20%), Positives = 53/115 (46%), Gaps = 5/115 (4%)
Query: 7 EQQRILRRHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQELEKF 66
EQQ + Q +R+E + Q S + + +R LL+ + + + E+A Q+LE+
Sbjct: 893 EQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKELADA-SQQLERL 951
Query: 67 QDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEE----RERQESIFQAEM 117
+ D ++ + E L+ + + + ++ R ++ +E S+ Q +M
Sbjct: 952 RQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKM 1006
Score = 28.9 bits (63), Expect = 5.5
Identities = 29/144 (20%), Positives = 62/144 (43%), Gaps = 14/144 (9%)
Query: 5 KSEQQRILRRHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQELE 64
+ E ++ + ++ER Q ++ S+ + +L + MEA AQ+ + +
Sbjct: 852 EKEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQ 911
Query: 65 --------KFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQES--IFQ 114
+ + + S++E L + E S + R R+ M+ ++ + QE+ I Q
Sbjct: 912 AESALCQMQLETEKERVSLLETLLQTQKE-LADASQQLERLRQDMKVQKLKEQETTGILQ 970
Query: 115 AEMSE---HLAGFKREEEEKLAAI 135
++ E L R+ + LAA+
Sbjct: 971 TQLQEAQRELKEAARQHRDDLAAL 994
Score = 28.1 bits (61), Expect = 9.3
Identities = 41/197 (20%), Positives = 76/197 (38%), Gaps = 26/197 (13%)
Query: 7 EQQRILRRHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQELEKF 66
E +L + ++E LQ Q++ + + K + L + + +AQ+ QELE
Sbjct: 1768 ETSLLLSQREQEIVVLQQQLQEAREQ----GELKEQSLQSQLDEAQRALAQRD-QELEAL 1822
Query: 67 QDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAE---------- 116
Q + E+ K + +AH + E ++ +E + E
Sbjct: 1823 QQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRV 1882
Query: 117 --MSEHLAGFKREEEEKLAAILGARGLEMKAIPADGH-CMYRAIQDQLVFSVSV------ 167
+ E L + E E+ A+L + + A A H RA+QD + + +V
Sbjct: 1883 QALEEVLGDLRAESREQEKALLALQ--QQCAEQAQEHEVETRALQDSWLQAQAVLKERDQ 1940
Query: 168 EMLRCRTASYMKKHVDE 184
E+ R S +H +E
Sbjct: 1941 ELEALRAESQSSRHQEE 1957
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 40.8 bits (94), Expect = 0.001
Identities = 38/145 (26%), Positives = 71/145 (48%), Gaps = 25/145 (17%)
Query: 1 MDDPKSEQQRILRRHQRERQELQAQIRSLKNSVPKTDKTKRKQLL--QDVARMEAEMAQK 58
+ + +E Q LR + E+ E+Q ++ LK K +R QLL Q ++EA+ K
Sbjct: 216 LKEKNAELQEKLRLVESEKSEIQLNVKDLKR------KLERAQLLLPQQQLQVEADRLGK 269
Query: 59 HRQELEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEE----------RER 108
Q + + +++ VE+ NL N+ + K R+ E+++ +E RE+
Sbjct: 270 ELQSV-----SAKLQAQVEENELWNLLNQ-QQEEKMWRQEEKIQEQEEKMCEQELKIREQ 323
Query: 109 QESIFQAEMSEHLAGFK-REEEEKL 132
+E +++ E H K RE+E+K+
Sbjct: 324 EEKMWRQEEKMHEQEEKIREQEDKM 348
Score = 37.7 bits (86), Expect = 0.012
Identities = 29/133 (21%), Positives = 64/133 (48%), Gaps = 5/133 (3%)
Query: 7 EQQRILRRHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEM---AQKHRQEL 63
EQ+ + R + + E + +IR ++ + + ++ R+Q + + E +M +K R++
Sbjct: 322 EQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQE-EKIREQEEKMWRQEEKIREQD 380
Query: 64 EKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIF-QAEMSEHLA 122
EK Q+ E+ + E R + + +K + + RE++E ++ Q E L
Sbjct: 381 EKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELE 440
Query: 123 GFKREEEEKLAAI 135
+++EEKL +
Sbjct: 441 EMMQDQEEKLREV 453
Score = 30.8 bits (68), Expect = 1.4
Identities = 24/105 (22%), Positives = 49/105 (46%), Gaps = 6/105 (5%)
Query: 17 RERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEM---AQKHRQELEKFQDDSSIE 73
R+ ++++ Q + + + +K R+Q + + E EM +K R+ E QD
Sbjct: 392 RQEEKIREQEEKRQEKMWRQEKKMREQD-EKIREQEEEMWRQEEKIRELEEMMQDQEEKL 450
Query: 74 SVVEDLAKMNLENRPPRSSKAHRKRERMESEERE--RQESIFQAE 116
VE+ + E + K R+ E+++ +E + RQE + + E
Sbjct: 451 REVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQE 495
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 40.8 bits (94), Expect = 0.001
Identities = 38/145 (26%), Positives = 71/145 (48%), Gaps = 25/145 (17%)
Query: 1 MDDPKSEQQRILRRHQRERQELQAQIRSLKNSVPKTDKTKRKQLL--QDVARMEAEMAQK 58
+ + +E Q LR + E+ E+Q ++ LK K +R QLL Q ++EA+ K
Sbjct: 216 LKEKNAELQEKLRLVESEKSEIQLNVKDLKR------KLERAQLLLPQQQLQVEADRLGK 269
Query: 59 HRQELEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEE----------RER 108
Q + + +++ VE+ NL N+ + K R+ E+++ +E RE+
Sbjct: 270 ELQSV-----SAKLQAQVEENELWNLLNQ-QQEEKMWRQEEKIQEQEEKMCEQELKIREQ 323
Query: 109 QESIFQAEMSEHLAGFK-REEEEKL 132
+E +++ E H K RE+E+K+
Sbjct: 324 EEKMWRQEEKMHEQEEKIREQEDKM 348
Score = 37.7 bits (86), Expect = 0.012
Identities = 29/133 (21%), Positives = 64/133 (48%), Gaps = 5/133 (3%)
Query: 7 EQQRILRRHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEM---AQKHRQEL 63
EQ+ + R + + E + +IR ++ + + ++ R+Q + + E +M +K R++
Sbjct: 322 EQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQE-EKIREQEEKMWRQEEKIREQD 380
Query: 64 EKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIF-QAEMSEHLA 122
EK Q+ E+ + E R + + +K + + RE++E ++ Q E L
Sbjct: 381 EKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELE 440
Query: 123 GFKREEEEKLAAI 135
+++EEKL +
Sbjct: 441 EMMQDQEEKLREV 453
Score = 30.8 bits (68), Expect = 1.4
Identities = 24/105 (22%), Positives = 49/105 (46%), Gaps = 6/105 (5%)
Query: 17 RERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEM---AQKHRQELEKFQDDSSIE 73
R+ ++++ Q + + + +K R+Q + + E EM +K R+ E QD
Sbjct: 392 RQEEKIREQEEKRQEKMWRQEKKMREQD-EKIREQEEEMWRQEEKIRELEEMMQDQEEKL 450
Query: 74 SVVEDLAKMNLENRPPRSSKAHRKRERMESEERE--RQESIFQAE 116
VE+ + E + K R+ E+++ +E + RQE + + E
Sbjct: 451 REVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQE 495
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 40.8 bits (94), Expect = 0.001
Identities = 35/161 (21%), Positives = 74/161 (45%), Gaps = 15/161 (9%)
Query: 14 RHQRERQELQA--QIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQELEKFQDDSS 71
R Q+E+ E A ++ ++ KT++ +RK + +++ + + Q+ S
Sbjct: 402 REQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSR 461
Query: 72 IESVVEDLAKMNLENRPPRSSKAHRKR---------ERMESEERERQESI---FQAEMSE 119
++ V D+ K + E + + K H K +++++ ERE QE + + SE
Sbjct: 462 VKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSE 521
Query: 120 HLAGFKREEEEKLAAILGARGLEMKAIPADGHCMYRAIQDQ 160
+L +E+E++ + L L+ KAI + R +Q +
Sbjct: 522 YLK-ISQEKEQQESLALEELELQKKAILTESENKLRDLQQE 561
Score = 37.7 bits (86), Expect = 0.012
Identities = 37/153 (24%), Positives = 72/153 (47%), Gaps = 21/153 (13%)
Query: 1 MDDPKSEQQRILRRHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARM--------E 52
M+D KS+ ++ + E + A+I L++ + T KT + L +V +
Sbjct: 1502 MEDDKSKMEKKESNLETELKSQTARIMELEDHI--TQKTIEIESLNEVLKNYNQQKDIEH 1559
Query: 53 AEMAQK--HRQELEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRE--------RME 102
E+ QK H QEL + + D+ ++ E + + + ++ +K+E + +
Sbjct: 1560 KELVQKLQHFQELGE-EKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSK 1618
Query: 103 SEERERQESIFQAEMSEHLAGFKREEEEKLAAI 135
EE + E ++E + LA KR+ E+K+AAI
Sbjct: 1619 EEELKALEDRLESESAAKLAELKRKAEQKIAAI 1651
Score = 35.4 bits (80), Expect = 0.058
Identities = 33/129 (25%), Positives = 60/129 (46%), Gaps = 22/129 (17%)
Query: 6 SEQQRILRRHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAE----------M 55
+E + LR Q+E + + +I L++S+ K+ + + Q +EAE M
Sbjct: 549 TESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVM 608
Query: 56 AQKHRQELE--KFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEER---ERQE 110
+KH+ ELE K Q D+ ++ L + ++ + RE+ E E+ + +E
Sbjct: 609 VEKHKTELESLKHQQDALWTEKLQVL-------KQQYQTEMEKLREKCEQEKETLLKDKE 661
Query: 111 SIFQAEMSE 119
IFQA + E
Sbjct: 662 IIFQAHIEE 670
Score = 28.9 bits (63), Expect = 5.5
Identities = 24/103 (23%), Positives = 50/103 (48%), Gaps = 18/103 (17%)
Query: 33 VPKTDKTKRKQLLQDVARMEA----------------EMAQKHRQELEKFQDDSSIESVV 76
V +D ++QL+Q + RME +M Q+ +++L+ S +S +
Sbjct: 128 VGNSDSLNKEQLIQRLRRMERSLSSYRGKYSELVTAYQMLQREKKKLQGILSQSQDKS-L 186
Query: 77 EDLAKMNLENRPPRSSKAHRKRERMES-EERERQESIFQAEMS 118
+A++ E + + +K H + E S EE+++ S+ Q ++S
Sbjct: 187 RRIAELREELQMDQQAKKHLQEEFDASLEEKDQYISVLQTQVS 229
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 40.8 bits (94), Expect = 0.001
Identities = 40/177 (22%), Positives = 81/177 (45%), Gaps = 17/177 (9%)
Query: 7 EQQRILRRHQRER-QELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKH------ 59
E +R LR+ + ER +++Q + + + S ++KR + A++E + ++H
Sbjct: 1547 EAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQL 1606
Query: 60 RQELEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSE 119
R+E E+ + + A+ LE ++++A R R +++EE +Q+S+ QAE +
Sbjct: 1607 REEAERRAQQQAEAERAREEAERELERWQLKANEALRLR--LQAEEVAQQKSLAQAEAEK 1664
Query: 120 HLAGFKR--------EEEEKLAAILGARGLEMKAIPADGHCMYRAIQDQLVFSVSVE 168
+R EE+ L + LE + A+G R +Q + + E
Sbjct: 1665 QKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAE 1721
Score = 38.9 bits (89), Expect = 0.005
Identities = 24/117 (20%), Positives = 59/117 (50%), Gaps = 2/117 (1%)
Query: 16 QRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQELEKFQDDSSIESV 75
+RE+++LQ + + L+ + +++QLLQ+ ++ + L++ + ++
Sbjct: 2456 EREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAK 2515
Query: 76 VEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSEHLA--GFKREEEE 130
+E L + + + R++++ME E + S+ +A +H A G +R++EE
Sbjct: 2516 LEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEE 2572
Score = 37.4 bits (85), Expect = 0.015
Identities = 37/142 (26%), Positives = 70/142 (49%), Gaps = 14/142 (9%)
Query: 5 KSEQQRILRRHQ--RERQELQAQIRSLKNSVPKTD------KTKRKQLLQD-VARMEAEM 55
KSE+ + +++ Q +E Q LQ S K+S+ + + K K +QL QD VA+ +
Sbjct: 2472 KSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLR 2531
Query: 56 AQKHRQELEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMES-EERERQESIFQ 114
++ RQ+ + Q+ + + +E+ + E RK+E ++ E++ RQ+
Sbjct: 2532 EEQQRQQQQMEQERQRLVASMEEARRRQHE----AEEGVRRKQEELQQLEQQRRQQEELL 2587
Query: 115 AEMSEHLAGFKREEEEKLAAIL 136
AE ++ L + EE+ A L
Sbjct: 2588 AEENQRLREQLQLLEEQHRAAL 2609
Score = 36.6 bits (83), Expect = 0.026
Identities = 36/136 (26%), Positives = 64/136 (47%), Gaps = 15/136 (11%)
Query: 16 QRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEM----AQKHRQELEKFQDDSS 71
+++RQ L+ ++ L+ + KR++L ++A++ AEM A K R E E
Sbjct: 1726 EQQRQLLEEELARLQREAAAATQ-KRQELEAELAKVRAEMEVLLASKARAEEESRS---- 1780
Query: 72 IESVVEDLAKMNLENRPPRSSKAHRKRERMES--EERERQESIFQAEMSEHLAGFKREEE 129
+ +K LE R + + R+ + EE +RQ + + + + A +R
Sbjct: 1781 ----TSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLA 1836
Query: 130 EKLAAILGARGLEMKA 145
EKLAAI A L+ +A
Sbjct: 1837 EKLAAIGEATRLKTEA 1852
Score = 32.7 bits (73), Expect = 0.38
Identities = 27/118 (22%), Positives = 53/118 (44%), Gaps = 5/118 (4%)
Query: 19 RQELQAQIRSLKNSVPKTDKTKRKQLLQDVARME--AEMAQKHRQELEKFQDDSSIESVV 76
+ EL+ ++ ++++ T ++K + L+ + + AE ++ R+ E+ Q + E
Sbjct: 1941 KAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEA 2000
Query: 77 EDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSEHLAGFKREEEEKLAA 134
K LE +K R ER QES Q ++++ A + + EEK A
Sbjct: 2001 ARQRKAALEEVERLKAKVEEARRL---RERAEQESARQLQLAQEAAQKRLQAEEKAHA 2055
Score = 30.8 bits (68), Expect = 1.4
Identities = 24/107 (22%), Positives = 51/107 (47%), Gaps = 9/107 (8%)
Query: 42 KQLLQDVARMEAEMAQKHRQELEKFQDDSSIESVVE---DLAKMNLENRPPRSSKAHRKR 98
K + + + RME E +Q E+ + + +E+ +E LA+ + + + +A +
Sbjct: 1335 KFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQ 1394
Query: 99 ERMESEERERQESIFQAEMSEHLAGFKREEEEKLAAILGARGLEMKA 145
+RM+ E R+E+ A+ KR +E+L + + E++A
Sbjct: 1395 QRMQEEVVRREEAAVDAQQQ------KRSIQEELQQLRQSSEAEIQA 1435
Score = 29.3 bits (64), Expect = 4.2
Identities = 24/134 (17%), Positives = 59/134 (44%), Gaps = 6/134 (4%)
Query: 3 DPKSEQQRILRRHQRERQELQAQIRSLKNSVPKTDKTK-RKQLLQDVARMEAEMAQKHRQ 61
D + +++ I Q+ RQ +A+I++ ++++ R + V R++ E ++ R
Sbjct: 1410 DAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRG 1469
Query: 62 ELEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSEHL 121
E ++++ + + R + +R+ + +R+RQ + A +
Sbjct: 1470 GAE-----GELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAE 1524
Query: 122 AGFKREEEEKLAAI 135
A RE++ L A+
Sbjct: 1525 AEAAREKQRALQAL 1538
Score = 28.9 bits (63), Expect = 5.5
Identities = 30/142 (21%), Positives = 59/142 (41%), Gaps = 21/142 (14%)
Query: 14 RHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQELEKFQDDSSIE 73
+H+ + +E AQ+R +S + ++K L++D R Q+ + E E +S E
Sbjct: 1886 QHKADIEERLAQLRKASDS----ELERQKGLVEDTLR------QRRQVEEEILALKASFE 1935
Query: 74 SVVEDLAKMNLEN-----------RPPRSSKAHRKRERMESEERERQESIFQAEMSEHLA 122
A++ LE R ++ R+R + E ER+ + + + LA
Sbjct: 1936 KAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLA 1995
Query: 123 GFKREEEEKLAAILGARGLEMK 144
+ ++ AA+ L+ K
Sbjct: 1996 AEEEAARQRKAALEEVERLKAK 2017
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 40.8 bits (94), Expect = 0.001
Identities = 40/177 (22%), Positives = 81/177 (45%), Gaps = 17/177 (9%)
Query: 7 EQQRILRRHQRER-QELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKH------ 59
E +R LR+ + ER +++Q + + + S ++KR + A++E + ++H
Sbjct: 1551 EAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQL 1610
Query: 60 RQELEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSE 119
R+E E+ + + A+ LE ++++A R R +++EE +Q+S+ QAE +
Sbjct: 1611 REEAERRAQQQAEAERAREEAERELERWQLKANEALRLR--LQAEEVAQQKSLAQAEAEK 1668
Query: 120 HLAGFKR--------EEEEKLAAILGARGLEMKAIPADGHCMYRAIQDQLVFSVSVE 168
+R EE+ L + LE + A+G R +Q + + E
Sbjct: 1669 QKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAE 1725
Score = 38.9 bits (89), Expect = 0.005
Identities = 24/117 (20%), Positives = 59/117 (50%), Gaps = 2/117 (1%)
Query: 16 QRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQELEKFQDDSSIESV 75
+RE+++LQ + + L+ + +++QLLQ+ ++ + L++ + ++
Sbjct: 2460 EREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAK 2519
Query: 76 VEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSEHLA--GFKREEEE 130
+E L + + + R++++ME E + S+ +A +H A G +R++EE
Sbjct: 2520 LEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEE 2576
Score = 37.4 bits (85), Expect = 0.015
Identities = 37/142 (26%), Positives = 70/142 (49%), Gaps = 14/142 (9%)
Query: 5 KSEQQRILRRHQ--RERQELQAQIRSLKNSVPKTD------KTKRKQLLQD-VARMEAEM 55
KSE+ + +++ Q +E Q LQ S K+S+ + + K K +QL QD VA+ +
Sbjct: 2476 KSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLR 2535
Query: 56 AQKHRQELEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMES-EERERQESIFQ 114
++ RQ+ + Q+ + + +E+ + E RK+E ++ E++ RQ+
Sbjct: 2536 EEQQRQQQQMEQERQRLVASMEEARRRQHE----AEEGVRRKQEELQQLEQQRRQQEELL 2591
Query: 115 AEMSEHLAGFKREEEEKLAAIL 136
AE ++ L + EE+ A L
Sbjct: 2592 AEENQRLREQLQLLEEQHRAAL 2613
Score = 36.6 bits (83), Expect = 0.026
Identities = 36/136 (26%), Positives = 64/136 (47%), Gaps = 15/136 (11%)
Query: 16 QRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEM----AQKHRQELEKFQDDSS 71
+++RQ L+ ++ L+ + KR++L ++A++ AEM A K R E E
Sbjct: 1730 EQQRQLLEEELARLQREAAAATQ-KRQELEAELAKVRAEMEVLLASKARAEEESRS---- 1784
Query: 72 IESVVEDLAKMNLENRPPRSSKAHRKRERMES--EERERQESIFQAEMSEHLAGFKREEE 129
+ +K LE R + + R+ + EE +RQ + + + + A +R
Sbjct: 1785 ----TSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLA 1840
Query: 130 EKLAAILGARGLEMKA 145
EKLAAI A L+ +A
Sbjct: 1841 EKLAAIGEATRLKTEA 1856
Score = 32.7 bits (73), Expect = 0.38
Identities = 27/118 (22%), Positives = 53/118 (44%), Gaps = 5/118 (4%)
Query: 19 RQELQAQIRSLKNSVPKTDKTKRKQLLQDVARME--AEMAQKHRQELEKFQDDSSIESVV 76
+ EL+ ++ ++++ T ++K + L+ + + AE ++ R+ E+ Q + E
Sbjct: 1945 KAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEA 2004
Query: 77 EDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSEHLAGFKREEEEKLAA 134
K LE +K R ER QES Q ++++ A + + EEK A
Sbjct: 2005 ARQRKAALEEVERLKAKVEEARRL---RERAEQESARQLQLAQEAAQKRLQAEEKAHA 2059
Score = 30.8 bits (68), Expect = 1.4
Identities = 24/107 (22%), Positives = 51/107 (47%), Gaps = 9/107 (8%)
Query: 42 KQLLQDVARMEAEMAQKHRQELEKFQDDSSIESVVE---DLAKMNLENRPPRSSKAHRKR 98
K + + + RME E +Q E+ + + +E+ +E LA+ + + + +A +
Sbjct: 1339 KFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQ 1398
Query: 99 ERMESEERERQESIFQAEMSEHLAGFKREEEEKLAAILGARGLEMKA 145
+RM+ E R+E+ A+ KR +E+L + + E++A
Sbjct: 1399 QRMQEEVVRREEAAVDAQQQ------KRSIQEELQQLRQSSEAEIQA 1439
Score = 29.3 bits (64), Expect = 4.2
Identities = 24/134 (17%), Positives = 59/134 (44%), Gaps = 6/134 (4%)
Query: 3 DPKSEQQRILRRHQRERQELQAQIRSLKNSVPKTDKTK-RKQLLQDVARMEAEMAQKHRQ 61
D + +++ I Q+ RQ +A+I++ ++++ R + V R++ E ++ R
Sbjct: 1414 DAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRG 1473
Query: 62 ELEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSEHL 121
E ++++ + + R + +R+ + +R+RQ + A +
Sbjct: 1474 GAE-----GELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAE 1528
Query: 122 AGFKREEEEKLAAI 135
A RE++ L A+
Sbjct: 1529 AEAAREKQRALQAL 1542
Score = 28.9 bits (63), Expect = 5.5
Identities = 30/142 (21%), Positives = 59/142 (41%), Gaps = 21/142 (14%)
Query: 14 RHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQELEKFQDDSSIE 73
+H+ + +E AQ+R +S + ++K L++D R Q+ + E E +S E
Sbjct: 1890 QHKADIEERLAQLRKASDS----ELERQKGLVEDTLR------QRRQVEEEILALKASFE 1939
Query: 74 SVVEDLAKMNLEN-----------RPPRSSKAHRKRERMESEERERQESIFQAEMSEHLA 122
A++ LE R ++ R+R + E ER+ + + + LA
Sbjct: 1940 KAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLA 1999
Query: 123 GFKREEEEKLAAILGARGLEMK 144
+ ++ AA+ L+ K
Sbjct: 2000 AEEEAARQRKAALEEVERLKAK 2021
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 40.8 bits (94), Expect = 0.001
Identities = 40/177 (22%), Positives = 81/177 (45%), Gaps = 17/177 (9%)
Query: 7 EQQRILRRHQRER-QELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKH------ 59
E +R LR+ + ER +++Q + + + S ++KR + A++E + ++H
Sbjct: 1547 EAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQL 1606
Query: 60 RQELEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSE 119
R+E E+ + + A+ LE ++++A R R +++EE +Q+S+ QAE +
Sbjct: 1607 REEAERRAQQQAEAERAREEAERELERWQLKANEALRLR--LQAEEVAQQKSLAQAEAEK 1664
Query: 120 HLAGFKR--------EEEEKLAAILGARGLEMKAIPADGHCMYRAIQDQLVFSVSVE 168
+R EE+ L + LE + A+G R +Q + + E
Sbjct: 1665 QKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAE 1721
Score = 38.9 bits (89), Expect = 0.005
Identities = 24/117 (20%), Positives = 59/117 (50%), Gaps = 2/117 (1%)
Query: 16 QRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQELEKFQDDSSIESV 75
+RE+++LQ + + L+ + +++QLLQ+ ++ + L++ + ++
Sbjct: 2456 EREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAK 2515
Query: 76 VEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSEHLA--GFKREEEE 130
+E L + + + R++++ME E + S+ +A +H A G +R++EE
Sbjct: 2516 LEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEE 2572
Score = 37.4 bits (85), Expect = 0.015
Identities = 37/142 (26%), Positives = 70/142 (49%), Gaps = 14/142 (9%)
Query: 5 KSEQQRILRRHQ--RERQELQAQIRSLKNSVPKTD------KTKRKQLLQD-VARMEAEM 55
KSE+ + +++ Q +E Q LQ S K+S+ + + K K +QL QD VA+ +
Sbjct: 2472 KSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLR 2531
Query: 56 AQKHRQELEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMES-EERERQESIFQ 114
++ RQ+ + Q+ + + +E+ + E RK+E ++ E++ RQ+
Sbjct: 2532 EEQQRQQQQMEQERQRLVASMEEARRRQHE----AEEGVRRKQEELQQLEQQRRQQEELL 2587
Query: 115 AEMSEHLAGFKREEEEKLAAIL 136
AE ++ L + EE+ A L
Sbjct: 2588 AEENQRLREQLQLLEEQHRAAL 2609
Score = 36.6 bits (83), Expect = 0.026
Identities = 36/136 (26%), Positives = 64/136 (47%), Gaps = 15/136 (11%)
Query: 16 QRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEM----AQKHRQELEKFQDDSS 71
+++RQ L+ ++ L+ + KR++L ++A++ AEM A K R E E
Sbjct: 1726 EQQRQLLEEELARLQREAAAATQ-KRQELEAELAKVRAEMEVLLASKARAEEESRS---- 1780
Query: 72 IESVVEDLAKMNLENRPPRSSKAHRKRERMES--EERERQESIFQAEMSEHLAGFKREEE 129
+ +K LE R + + R+ + EE +RQ + + + + A +R
Sbjct: 1781 ----TSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLA 1836
Query: 130 EKLAAILGARGLEMKA 145
EKLAAI A L+ +A
Sbjct: 1837 EKLAAIGEATRLKTEA 1852
Score = 32.7 bits (73), Expect = 0.38
Identities = 27/118 (22%), Positives = 53/118 (44%), Gaps = 5/118 (4%)
Query: 19 RQELQAQIRSLKNSVPKTDKTKRKQLLQDVARME--AEMAQKHRQELEKFQDDSSIESVV 76
+ EL+ ++ ++++ T ++K + L+ + + AE ++ R+ E+ Q + E
Sbjct: 1941 KAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEA 2000
Query: 77 EDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSEHLAGFKREEEEKLAA 134
K LE +K R ER QES Q ++++ A + + EEK A
Sbjct: 2001 ARQRKAALEEVERLKAKVEEARRL---RERAEQESARQLQLAQEAAQKRLQAEEKAHA 2055
Score = 30.8 bits (68), Expect = 1.4
Identities = 24/107 (22%), Positives = 51/107 (47%), Gaps = 9/107 (8%)
Query: 42 KQLLQDVARMEAEMAQKHRQELEKFQDDSSIESVVE---DLAKMNLENRPPRSSKAHRKR 98
K + + + RME E +Q E+ + + +E+ +E LA+ + + + +A +
Sbjct: 1335 KFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQ 1394
Query: 99 ERMESEERERQESIFQAEMSEHLAGFKREEEEKLAAILGARGLEMKA 145
+RM+ E R+E+ A+ KR +E+L + + E++A
Sbjct: 1395 QRMQEEVVRREEAAVDAQQQ------KRSIQEELQQLRQSSEAEIQA 1435
Score = 29.3 bits (64), Expect = 4.2
Identities = 24/134 (17%), Positives = 59/134 (44%), Gaps = 6/134 (4%)
Query: 3 DPKSEQQRILRRHQRERQELQAQIRSLKNSVPKTDKTK-RKQLLQDVARMEAEMAQKHRQ 61
D + +++ I Q+ RQ +A+I++ ++++ R + V R++ E ++ R
Sbjct: 1410 DAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRG 1469
Query: 62 ELEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSEHL 121
E ++++ + + R + +R+ + +R+RQ + A +
Sbjct: 1470 GAE-----GELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAE 1524
Query: 122 AGFKREEEEKLAAI 135
A RE++ L A+
Sbjct: 1525 AEAAREKQRALQAL 1538
Score = 28.9 bits (63), Expect = 5.5
Identities = 30/142 (21%), Positives = 59/142 (41%), Gaps = 21/142 (14%)
Query: 14 RHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQELEKFQDDSSIE 73
+H+ + +E AQ+R +S + ++K L++D R Q+ + E E +S E
Sbjct: 1886 QHKADIEERLAQLRKASDS----ELERQKGLVEDTLR------QRRQVEEEILALKASFE 1935
Query: 74 SVVEDLAKMNLEN-----------RPPRSSKAHRKRERMESEERERQESIFQAEMSEHLA 122
A++ LE R ++ R+R + E ER+ + + + LA
Sbjct: 1936 KAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLA 1995
Query: 123 GFKREEEEKLAAILGARGLEMK 144
+ ++ AA+ L+ K
Sbjct: 1996 AEEEAARQRKAALEEVERLKAK 2017
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 40.8 bits (94), Expect = 0.001
Identities = 40/177 (22%), Positives = 81/177 (45%), Gaps = 17/177 (9%)
Query: 7 EQQRILRRHQRER-QELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKH------ 59
E +R LR+ + ER +++Q + + + S ++KR + A++E + ++H
Sbjct: 1515 EAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQL 1574
Query: 60 RQELEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSE 119
R+E E+ + + A+ LE ++++A R R +++EE +Q+S+ QAE +
Sbjct: 1575 REEAERRAQQQAEAERAREEAERELERWQLKANEALRLR--LQAEEVAQQKSLAQAEAEK 1632
Query: 120 HLAGFKR--------EEEEKLAAILGARGLEMKAIPADGHCMYRAIQDQLVFSVSVE 168
+R EE+ L + LE + A+G R +Q + + E
Sbjct: 1633 QKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAE 1689
Score = 38.9 bits (89), Expect = 0.005
Identities = 24/117 (20%), Positives = 59/117 (50%), Gaps = 2/117 (1%)
Query: 16 QRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQELEKFQDDSSIESV 75
+RE+++LQ + + L+ + +++QLLQ+ ++ + L++ + ++
Sbjct: 2424 EREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAK 2483
Query: 76 VEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSEHLA--GFKREEEE 130
+E L + + + R++++ME E + S+ +A +H A G +R++EE
Sbjct: 2484 LEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEE 2540
Score = 37.4 bits (85), Expect = 0.015
Identities = 37/142 (26%), Positives = 70/142 (49%), Gaps = 14/142 (9%)
Query: 5 KSEQQRILRRHQ--RERQELQAQIRSLKNSVPKTD------KTKRKQLLQD-VARMEAEM 55
KSE+ + +++ Q +E Q LQ S K+S+ + + K K +QL QD VA+ +
Sbjct: 2440 KSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLR 2499
Query: 56 AQKHRQELEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMES-EERERQESIFQ 114
++ RQ+ + Q+ + + +E+ + E RK+E ++ E++ RQ+
Sbjct: 2500 EEQQRQQQQMEQERQRLVASMEEARRRQHE----AEEGVRRKQEELQQLEQQRRQQEELL 2555
Query: 115 AEMSEHLAGFKREEEEKLAAIL 136
AE ++ L + EE+ A L
Sbjct: 2556 AEENQRLREQLQLLEEQHRAAL 2577
Score = 36.6 bits (83), Expect = 0.026
Identities = 36/136 (26%), Positives = 64/136 (47%), Gaps = 15/136 (11%)
Query: 16 QRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEM----AQKHRQELEKFQDDSS 71
+++RQ L+ ++ L+ + KR++L ++A++ AEM A K R E E
Sbjct: 1694 EQQRQLLEEELARLQREAAAATQ-KRQELEAELAKVRAEMEVLLASKARAEEESRS---- 1748
Query: 72 IESVVEDLAKMNLENRPPRSSKAHRKRERMES--EERERQESIFQAEMSEHLAGFKREEE 129
+ +K LE R + + R+ + EE +RQ + + + + A +R
Sbjct: 1749 ----TSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLA 1804
Query: 130 EKLAAILGARGLEMKA 145
EKLAAI A L+ +A
Sbjct: 1805 EKLAAIGEATRLKTEA 1820
Score = 32.7 bits (73), Expect = 0.38
Identities = 27/118 (22%), Positives = 53/118 (44%), Gaps = 5/118 (4%)
Query: 19 RQELQAQIRSLKNSVPKTDKTKRKQLLQDVARME--AEMAQKHRQELEKFQDDSSIESVV 76
+ EL+ ++ ++++ T ++K + L+ + + AE ++ R+ E+ Q + E
Sbjct: 1909 KAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEA 1968
Query: 77 EDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSEHLAGFKREEEEKLAA 134
K LE +K R ER QES Q ++++ A + + EEK A
Sbjct: 1969 ARQRKAALEEVERLKAKVEEARRL---RERAEQESARQLQLAQEAAQKRLQAEEKAHA 2023
Score = 30.8 bits (68), Expect = 1.4
Identities = 24/107 (22%), Positives = 51/107 (47%), Gaps = 9/107 (8%)
Query: 42 KQLLQDVARMEAEMAQKHRQELEKFQDDSSIESVVE---DLAKMNLENRPPRSSKAHRKR 98
K + + + RME E +Q E+ + + +E+ +E LA+ + + + +A +
Sbjct: 1303 KFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQ 1362
Query: 99 ERMESEERERQESIFQAEMSEHLAGFKREEEEKLAAILGARGLEMKA 145
+RM+ E R+E+ A+ KR +E+L + + E++A
Sbjct: 1363 QRMQEEVVRREEAAVDAQQQ------KRSIQEELQQLRQSSEAEIQA 1403
Score = 29.3 bits (64), Expect = 4.2
Identities = 24/134 (17%), Positives = 59/134 (44%), Gaps = 6/134 (4%)
Query: 3 DPKSEQQRILRRHQRERQELQAQIRSLKNSVPKTDKTK-RKQLLQDVARMEAEMAQKHRQ 61
D + +++ I Q+ RQ +A+I++ ++++ R + V R++ E ++ R
Sbjct: 1378 DAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRG 1437
Query: 62 ELEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSEHL 121
E ++++ + + R + +R+ + +R+RQ + A +
Sbjct: 1438 GAE-----GELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAE 1492
Query: 122 AGFKREEEEKLAAI 135
A RE++ L A+
Sbjct: 1493 AEAAREKQRALQAL 1506
Score = 28.9 bits (63), Expect = 5.5
Identities = 30/142 (21%), Positives = 59/142 (41%), Gaps = 21/142 (14%)
Query: 14 RHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQELEKFQDDSSIE 73
+H+ + +E AQ+R +S + ++K L++D R Q+ + E E +S E
Sbjct: 1854 QHKADIEERLAQLRKASDS----ELERQKGLVEDTLR------QRRQVEEEILALKASFE 1903
Query: 74 SVVEDLAKMNLEN-----------RPPRSSKAHRKRERMESEERERQESIFQAEMSEHLA 122
A++ LE R ++ R+R + E ER+ + + + LA
Sbjct: 1904 KAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLA 1963
Query: 123 GFKREEEEKLAAILGARGLEMK 144
+ ++ AA+ L+ K
Sbjct: 1964 AEEEAARQRKAALEEVERLKAK 1985
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 40.8 bits (94), Expect = 0.001
Identities = 40/177 (22%), Positives = 81/177 (45%), Gaps = 17/177 (9%)
Query: 7 EQQRILRRHQRER-QELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKH------ 59
E +R LR+ + ER +++Q + + + S ++KR + A++E + ++H
Sbjct: 1684 EAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQL 1743
Query: 60 RQELEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSE 119
R+E E+ + + A+ LE ++++A R R +++EE +Q+S+ QAE +
Sbjct: 1744 REEAERRAQQQAEAERAREEAERELERWQLKANEALRLR--LQAEEVAQQKSLAQAEAEK 1801
Query: 120 HLAGFKR--------EEEEKLAAILGARGLEMKAIPADGHCMYRAIQDQLVFSVSVE 168
+R EE+ L + LE + A+G R +Q + + E
Sbjct: 1802 QKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAE 1858
Score = 38.9 bits (89), Expect = 0.005
Identities = 24/117 (20%), Positives = 59/117 (50%), Gaps = 2/117 (1%)
Query: 16 QRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQELEKFQDDSSIESV 75
+RE+++LQ + + L+ + +++QLLQ+ ++ + L++ + ++
Sbjct: 2593 EREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAK 2652
Query: 76 VEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSEHLA--GFKREEEE 130
+E L + + + R++++ME E + S+ +A +H A G +R++EE
Sbjct: 2653 LEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEE 2709
Score = 37.4 bits (85), Expect = 0.015
Identities = 37/142 (26%), Positives = 70/142 (49%), Gaps = 14/142 (9%)
Query: 5 KSEQQRILRRHQ--RERQELQAQIRSLKNSVPKTD------KTKRKQLLQD-VARMEAEM 55
KSE+ + +++ Q +E Q LQ S K+S+ + + K K +QL QD VA+ +
Sbjct: 2609 KSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLR 2668
Query: 56 AQKHRQELEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMES-EERERQESIFQ 114
++ RQ+ + Q+ + + +E+ + E RK+E ++ E++ RQ+
Sbjct: 2669 EEQQRQQQQMEQERQRLVASMEEARRRQHE----AEEGVRRKQEELQQLEQQRRQQEELL 2724
Query: 115 AEMSEHLAGFKREEEEKLAAIL 136
AE ++ L + EE+ A L
Sbjct: 2725 AEENQRLREQLQLLEEQHRAAL 2746
Score = 36.6 bits (83), Expect = 0.026
Identities = 36/136 (26%), Positives = 64/136 (47%), Gaps = 15/136 (11%)
Query: 16 QRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEM----AQKHRQELEKFQDDSS 71
+++RQ L+ ++ L+ + KR++L ++A++ AEM A K R E E
Sbjct: 1863 EQQRQLLEEELARLQREAAAATQ-KRQELEAELAKVRAEMEVLLASKARAEEESRS---- 1917
Query: 72 IESVVEDLAKMNLENRPPRSSKAHRKRERMES--EERERQESIFQAEMSEHLAGFKREEE 129
+ +K LE R + + R+ + EE +RQ + + + + A +R
Sbjct: 1918 ----TSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLA 1973
Query: 130 EKLAAILGARGLEMKA 145
EKLAAI A L+ +A
Sbjct: 1974 EKLAAIGEATRLKTEA 1989
Score = 32.7 bits (73), Expect = 0.38
Identities = 27/118 (22%), Positives = 53/118 (44%), Gaps = 5/118 (4%)
Query: 19 RQELQAQIRSLKNSVPKTDKTKRKQLLQDVARME--AEMAQKHRQELEKFQDDSSIESVV 76
+ EL+ ++ ++++ T ++K + L+ + + AE ++ R+ E+ Q + E
Sbjct: 2078 KAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEA 2137
Query: 77 EDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSEHLAGFKREEEEKLAA 134
K LE +K R ER QES Q ++++ A + + EEK A
Sbjct: 2138 ARQRKAALEEVERLKAKVEEARRL---RERAEQESARQLQLAQEAAQKRLQAEEKAHA 2192
Score = 30.8 bits (68), Expect = 1.4
Identities = 24/107 (22%), Positives = 51/107 (47%), Gaps = 9/107 (8%)
Query: 42 KQLLQDVARMEAEMAQKHRQELEKFQDDSSIESVVE---DLAKMNLENRPPRSSKAHRKR 98
K + + + RME E +Q E+ + + +E+ +E LA+ + + + +A +
Sbjct: 1472 KFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQ 1531
Query: 99 ERMESEERERQESIFQAEMSEHLAGFKREEEEKLAAILGARGLEMKA 145
+RM+ E R+E+ A+ KR +E+L + + E++A
Sbjct: 1532 QRMQEEVVRREEAAVDAQQQ------KRSIQEELQQLRQSSEAEIQA 1572
Score = 29.3 bits (64), Expect = 4.2
Identities = 24/134 (17%), Positives = 59/134 (44%), Gaps = 6/134 (4%)
Query: 3 DPKSEQQRILRRHQRERQELQAQIRSLKNSVPKTDKTK-RKQLLQDVARMEAEMAQKHRQ 61
D + +++ I Q+ RQ +A+I++ ++++ R + V R++ E ++ R
Sbjct: 1547 DAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRG 1606
Query: 62 ELEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSEHL 121
E ++++ + + R + +R+ + +R+RQ + A +
Sbjct: 1607 GAE-----GELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAE 1661
Query: 122 AGFKREEEEKLAAI 135
A RE++ L A+
Sbjct: 1662 AEAAREKQRALQAL 1675
Score = 28.9 bits (63), Expect = 5.5
Identities = 30/142 (21%), Positives = 59/142 (41%), Gaps = 21/142 (14%)
Query: 14 RHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQELEKFQDDSSIE 73
+H+ + +E AQ+R +S + ++K L++D R Q+ + E E +S E
Sbjct: 2023 QHKADIEERLAQLRKASDS----ELERQKGLVEDTLR------QRRQVEEEILALKASFE 2072
Query: 74 SVVEDLAKMNLEN-----------RPPRSSKAHRKRERMESEERERQESIFQAEMSEHLA 122
A++ LE R ++ R+R + E ER+ + + + LA
Sbjct: 2073 KAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLA 2132
Query: 123 GFKREEEEKLAAILGARGLEMK 144
+ ++ AA+ L+ K
Sbjct: 2133 AEEEAARQRKAALEEVERLKAK 2154
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 40.8 bits (94), Expect = 0.001
Identities = 40/177 (22%), Positives = 81/177 (45%), Gaps = 17/177 (9%)
Query: 7 EQQRILRRHQRER-QELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKH------ 59
E +R LR+ + ER +++Q + + + S ++KR + A++E + ++H
Sbjct: 1525 EAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQL 1584
Query: 60 RQELEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSE 119
R+E E+ + + A+ LE ++++A R R +++EE +Q+S+ QAE +
Sbjct: 1585 REEAERRAQQQAEAERAREEAERELERWQLKANEALRLR--LQAEEVAQQKSLAQAEAEK 1642
Query: 120 HLAGFKR--------EEEEKLAAILGARGLEMKAIPADGHCMYRAIQDQLVFSVSVE 168
+R EE+ L + LE + A+G R +Q + + E
Sbjct: 1643 QKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAE 1699
Score = 38.9 bits (89), Expect = 0.005
Identities = 24/117 (20%), Positives = 59/117 (50%), Gaps = 2/117 (1%)
Query: 16 QRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQELEKFQDDSSIESV 75
+RE+++LQ + + L+ + +++QLLQ+ ++ + L++ + ++
Sbjct: 2434 EREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAK 2493
Query: 76 VEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSEHLA--GFKREEEE 130
+E L + + + R++++ME E + S+ +A +H A G +R++EE
Sbjct: 2494 LEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEE 2550
Score = 37.4 bits (85), Expect = 0.015
Identities = 37/142 (26%), Positives = 70/142 (49%), Gaps = 14/142 (9%)
Query: 5 KSEQQRILRRHQ--RERQELQAQIRSLKNSVPKTD------KTKRKQLLQD-VARMEAEM 55
KSE+ + +++ Q +E Q LQ S K+S+ + + K K +QL QD VA+ +
Sbjct: 2450 KSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLR 2509
Query: 56 AQKHRQELEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMES-EERERQESIFQ 114
++ RQ+ + Q+ + + +E+ + E RK+E ++ E++ RQ+
Sbjct: 2510 EEQQRQQQQMEQERQRLVASMEEARRRQHE----AEEGVRRKQEELQQLEQQRRQQEELL 2565
Query: 115 AEMSEHLAGFKREEEEKLAAIL 136
AE ++ L + EE+ A L
Sbjct: 2566 AEENQRLREQLQLLEEQHRAAL 2587
Score = 36.6 bits (83), Expect = 0.026
Identities = 36/136 (26%), Positives = 64/136 (47%), Gaps = 15/136 (11%)
Query: 16 QRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEM----AQKHRQELEKFQDDSS 71
+++RQ L+ ++ L+ + KR++L ++A++ AEM A K R E E
Sbjct: 1704 EQQRQLLEEELARLQREAAAATQ-KRQELEAELAKVRAEMEVLLASKARAEEESRS---- 1758
Query: 72 IESVVEDLAKMNLENRPPRSSKAHRKRERMES--EERERQESIFQAEMSEHLAGFKREEE 129
+ +K LE R + + R+ + EE +RQ + + + + A +R
Sbjct: 1759 ----TSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLA 1814
Query: 130 EKLAAILGARGLEMKA 145
EKLAAI A L+ +A
Sbjct: 1815 EKLAAIGEATRLKTEA 1830
Score = 32.7 bits (73), Expect = 0.38
Identities = 27/118 (22%), Positives = 53/118 (44%), Gaps = 5/118 (4%)
Query: 19 RQELQAQIRSLKNSVPKTDKTKRKQLLQDVARME--AEMAQKHRQELEKFQDDSSIESVV 76
+ EL+ ++ ++++ T ++K + L+ + + AE ++ R+ E+ Q + E
Sbjct: 1919 KAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEA 1978
Query: 77 EDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSEHLAGFKREEEEKLAA 134
K LE +K R ER QES Q ++++ A + + EEK A
Sbjct: 1979 ARQRKAALEEVERLKAKVEEARRL---RERAEQESARQLQLAQEAAQKRLQAEEKAHA 2033
Score = 30.8 bits (68), Expect = 1.4
Identities = 24/107 (22%), Positives = 51/107 (47%), Gaps = 9/107 (8%)
Query: 42 KQLLQDVARMEAEMAQKHRQELEKFQDDSSIESVVE---DLAKMNLENRPPRSSKAHRKR 98
K + + + RME E +Q E+ + + +E+ +E LA+ + + + +A +
Sbjct: 1313 KFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQ 1372
Query: 99 ERMESEERERQESIFQAEMSEHLAGFKREEEEKLAAILGARGLEMKA 145
+RM+ E R+E+ A+ KR +E+L + + E++A
Sbjct: 1373 QRMQEEVVRREEAAVDAQQQ------KRSIQEELQQLRQSSEAEIQA 1413
Score = 29.3 bits (64), Expect = 4.2
Identities = 24/134 (17%), Positives = 59/134 (44%), Gaps = 6/134 (4%)
Query: 3 DPKSEQQRILRRHQRERQELQAQIRSLKNSVPKTDKTK-RKQLLQDVARMEAEMAQKHRQ 61
D + +++ I Q+ RQ +A+I++ ++++ R + V R++ E ++ R
Sbjct: 1388 DAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRG 1447
Query: 62 ELEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSEHL 121
E ++++ + + R + +R+ + +R+RQ + A +
Sbjct: 1448 GAE-----GELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAE 1502
Query: 122 AGFKREEEEKLAAI 135
A RE++ L A+
Sbjct: 1503 AEAAREKQRALQAL 1516
Score = 28.9 bits (63), Expect = 5.5
Identities = 30/142 (21%), Positives = 59/142 (41%), Gaps = 21/142 (14%)
Query: 14 RHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQELEKFQDDSSIE 73
+H+ + +E AQ+R +S + ++K L++D R Q+ + E E +S E
Sbjct: 1864 QHKADIEERLAQLRKASDS----ELERQKGLVEDTLR------QRRQVEEEILALKASFE 1913
Query: 74 SVVEDLAKMNLEN-----------RPPRSSKAHRKRERMESEERERQESIFQAEMSEHLA 122
A++ LE R ++ R+R + E ER+ + + + LA
Sbjct: 1914 KAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLA 1973
Query: 123 GFKREEEEKLAAILGARGLEMK 144
+ ++ AA+ L+ K
Sbjct: 1974 AEEEAARQRKAALEEVERLKAK 1995
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.132 0.368
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,353,389
Number of Sequences: 37866
Number of extensions: 434208
Number of successful extensions: 5082
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 108
Number of HSP's successfully gapped in prelim test: 491
Number of HSP's that attempted gapping in prelim test: 3215
Number of HSP's gapped (non-prelim): 1726
length of query: 288
length of database: 18,247,518
effective HSP length: 101
effective length of query: 187
effective length of database: 14,423,052
effective search space: 2697110724
effective search space used: 2697110724
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.