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Search of human proteins with 46358403
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|46358403 ring finger protein 216 isoform a [Homo sapiens]
(923 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|46358403 ring finger protein 216 isoform a [Homo sapiens] 1930 0.0
gi|46370057 ring finger protein 216 isoform b [Homo sapiens] 1746 0.0
gi|38045938 ring finger protein 144 [Homo sapiens] 83 1e-15
gi|5454168 RanBP-type and C3HC4-type zinc finger containing 1 is... 70 9e-12
gi|144953898 RanBP-type and C3HC4-type zinc finger containing 1 ... 70 9e-12
gi|35493801 ring finger protein 19 [Homo sapiens] 69 2e-11
gi|35493782 ring finger protein 19 [Homo sapiens] 69 2e-11
gi|34577102 ring finger protein 14 isoform 1 [Homo sapiens] 64 6e-10
gi|34577100 ring finger protein 14 isoform 1 [Homo sapiens] 64 6e-10
gi|34577098 ring finger protein 14 isoform 1 [Homo sapiens] 64 6e-10
gi|34577096 ring finger protein 14 isoform 2 [Homo sapiens] 64 6e-10
gi|4757762 ring finger protein 14 isoform 1 [Homo sapiens] 64 6e-10
gi|188219577 ring finger protein 19B isoform a [Homo sapiens] 64 8e-10
gi|188219579 ring finger protein 19B isoform b [Homo sapiens] 62 2e-09
gi|187761373 ariadne ubiquitin-conjugating enzyme E2 binding pro... 62 2e-09
gi|5453557 ariadne homolog 2 [Homo sapiens] 62 3e-09
gi|22749145 ring finger protein 217 [Homo sapiens] 58 4e-08
gi|50284696 IBR domain containing 2 [Homo sapiens] 55 4e-07
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 50 1e-05
gi|157168329 formin 1 [Homo sapiens] 45 4e-04
gi|169790973 parkin isoform 3 [Homo sapiens] 44 5e-04
gi|169790971 parkin isoform 2 [Homo sapiens] 44 5e-04
gi|169790969 parkin isoform 1 [Homo sapiens] 44 5e-04
gi|215820635 protein phosphatase 1, regulatory subunit 13 like [... 44 7e-04
gi|63003907 protein phosphatase 1, regulatory subunit 13 like [H... 44 7e-04
gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3 ... 42 0.003
gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2 ... 42 0.003
gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1 [... 42 0.003
gi|239753435 PREDICTED: hypothetical protein XP_002345651 [Homo ... 41 0.006
gi|239747993 PREDICTED: hypothetical protein XP_002346504 [Homo ... 41 0.006
>gi|46358403 ring finger protein 216 isoform a [Homo sapiens]
Length = 923
Score = 1930 bits (4999), Expect = 0.0
Identities = 923/923 (100%), Positives = 923/923 (100%)
Query: 1 MEEGNNNEEVIHLNNFHCHRGQEWINLRDGPITISDSSDEERIPMLVTPAPQQHEEEDLD 60
MEEGNNNEEVIHLNNFHCHRGQEWINLRDGPITISDSSDEERIPMLVTPAPQQHEEEDLD
Sbjct: 1 MEEGNNNEEVIHLNNFHCHRGQEWINLRDGPITISDSSDEERIPMLVTPAPQQHEEEDLD 60
Query: 61 DDVILTETNKPQRSRPNLIKPAAQWQDLKRLGEERPKKSRAAFESDKSSYFSVCNNPLFD 120
DDVILTETNKPQRSRPNLIKPAAQWQDLKRLGEERPKKSRAAFESDKSSYFSVCNNPLFD
Sbjct: 61 DDVILTETNKPQRSRPNLIKPAAQWQDLKRLGEERPKKSRAAFESDKSSYFSVCNNPLFD 120
Query: 121 SGAQDDSEDDYGEFLDLGPPGISEFTKPSGQTEREPKPGPSHNQAANDIVNPRSEQKVII 180
SGAQDDSEDDYGEFLDLGPPGISEFTKPSGQTEREPKPGPSHNQAANDIVNPRSEQKVII
Sbjct: 121 SGAQDDSEDDYGEFLDLGPPGISEFTKPSGQTEREPKPGPSHNQAANDIVNPRSEQKVII 180
Query: 181 LEEGSLLYTESDPLETQNQSSEDSETELLSNLGESAALADDQAIEEDCWLDHPYFQSLNQ 240
LEEGSLLYTESDPLETQNQSSEDSETELLSNLGESAALADDQAIEEDCWLDHPYFQSLNQ
Sbjct: 181 LEEGSLLYTESDPLETQNQSSEDSETELLSNLGESAALADDQAIEEDCWLDHPYFQSLNQ 240
Query: 241 QPREITNQVVPQERQPEAELGRLLFQHEFPGPAFPRPEPQQGGISGPSSPQPAHPLGEFE 300
QPREITNQVVPQERQPEAELGRLLFQHEFPGPAFPRPEPQQGGISGPSSPQPAHPLGEFE
Sbjct: 241 QPREITNQVVPQERQPEAELGRLLFQHEFPGPAFPRPEPQQGGISGPSSPQPAHPLGEFE 300
Query: 301 DQQLASDDEEPGPAFPMQESQEPNLENIWGQEAAEVDQELVELLVKETEARFPDVANGFI 360
DQQLASDDEEPGPAFPMQESQEPNLENIWGQEAAEVDQELVELLVKETEARFPDVANGFI
Sbjct: 301 DQQLASDDEEPGPAFPMQESQEPNLENIWGQEAAEVDQELVELLVKETEARFPDVANGFI 360
Query: 361 EEIIHFKNYYDLNVLCNFLLENPDYPKREDRIIINPSSSLLASQDETKLPKIDFFDYSKL 420
EEIIHFKNYYDLNVLCNFLLENPDYPKREDRIIINPSSSLLASQDETKLPKIDFFDYSKL
Sbjct: 361 EEIIHFKNYYDLNVLCNFLLENPDYPKREDRIIINPSSSLLASQDETKLPKIDFFDYSKL 420
Query: 421 TPLDQRCFIQAADLLMADFKVLSSQDIKWALHELKGHYAITRKALSDAIKKWQELSPETS 480
TPLDQRCFIQAADLLMADFKVLSSQDIKWALHELKGHYAITRKALSDAIKKWQELSPETS
Sbjct: 421 TPLDQRCFIQAADLLMADFKVLSSQDIKWALHELKGHYAITRKALSDAIKKWQELSPETS 480
Query: 481 GKRKKRKQMNQYSYIDFKFEQGDIKIEKRMFFLENKRRHCRSYDRRALLPAVQQEQEFYE 540
GKRKKRKQMNQYSYIDFKFEQGDIKIEKRMFFLENKRRHCRSYDRRALLPAVQQEQEFYE
Sbjct: 481 GKRKKRKQMNQYSYIDFKFEQGDIKIEKRMFFLENKRRHCRSYDRRALLPAVQQEQEFYE 540
Query: 541 QKIKEMAEHEDFLLALQMNEEQYQKDGQLIECRCCYGEFPFEELTQCADAHLFCKECLIR 600
QKIKEMAEHEDFLLALQMNEEQYQKDGQLIECRCCYGEFPFEELTQCADAHLFCKECLIR
Sbjct: 541 QKIKEMAEHEDFLLALQMNEEQYQKDGQLIECRCCYGEFPFEELTQCADAHLFCKECLIR 600
Query: 601 YAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKYYERKAEEEVAAAYADELV 660
YAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKYYERKAEEEVAAAYADELV
Sbjct: 601 YAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKYYERKAEEEVAAAYADELV 660
Query: 661 RCPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNGLTCEELAEKDDIKYRTSI 720
RCPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNGLTCEELAEKDDIKYRTSI
Sbjct: 661 RCPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNGLTCEELAEKDDIKYRTSI 720
Query: 721 EEKMTAARIRKCHKCGTGLIKSEGCNRMSCRCGAQMCYLCRVSINGYDHFCQHPRSPGAP 780
EEKMTAARIRKCHKCGTGLIKSEGCNRMSCRCGAQMCYLCRVSINGYDHFCQHPRSPGAP
Sbjct: 721 EEKMTAARIRKCHKCGTGLIKSEGCNRMSCRCGAQMCYLCRVSINGYDHFCQHPRSPGAP 780
Query: 781 CQECSRCSLWTDPTEDDEKLIEEIQKEAEEEQKRKNGENTFKRIGPPLEKPVEKVQRVEA 840
CQECSRCSLWTDPTEDDEKLIEEIQKEAEEEQKRKNGENTFKRIGPPLEKPVEKVQRVEA
Sbjct: 781 CQECSRCSLWTDPTEDDEKLIEEIQKEAEEEQKRKNGENTFKRIGPPLEKPVEKVQRVEA 840
Query: 841 LPRPVPQNLPQPQMPPYAFAHPPFPLPPVRPVFNNFPLNMGPIPAPYVPPLPNVRVNYDF 900
LPRPVPQNLPQPQMPPYAFAHPPFPLPPVRPVFNNFPLNMGPIPAPYVPPLPNVRVNYDF
Sbjct: 841 LPRPVPQNLPQPQMPPYAFAHPPFPLPPVRPVFNNFPLNMGPIPAPYVPPLPNVRVNYDF 900
Query: 901 GPIHMPLEHNLPMHFGPQPRHRF 923
GPIHMPLEHNLPMHFGPQPRHRF
Sbjct: 901 GPIHMPLEHNLPMHFGPQPRHRF 923
>gi|46370057 ring finger protein 216 isoform b [Homo sapiens]
Length = 866
Score = 1746 bits (4523), Expect = 0.0
Identities = 849/923 (91%), Positives = 855/923 (92%), Gaps = 57/923 (6%)
Query: 1 MEEGNNNEEVIHLNNFHCHRGQEWINLRDGPITISDSSDEERIPMLVTPAPQQHEEEDLD 60
MEEGNNNEEVIHLNNFHCHRGQEWINLRDGPITISDSSDEERIPM
Sbjct: 1 MEEGNNNEEVIHLNNFHCHRGQEWINLRDGPITISDSSDEERIPM--------------- 45
Query: 61 DDVILTETNKPQRSRPNLIKPAAQWQDLKRLGEERPKKSRAAFESDKSSYFSVCNNPLFD 120
L+ PA Q + + L ++
Sbjct: 46 -----------------LVTPAPQQHEEEDLDDDVIL----------------------- 65
Query: 121 SGAQDDSEDDYGEFLDLGPPGISEFTKPSGQTEREPKPGPSHNQAANDIVNPRSEQKVII 180
+DDSEDDYGEFLDLGPPGISEFTKPSGQTEREPKPGPSHNQAANDIVNPRSEQKVII
Sbjct: 66 --TEDDSEDDYGEFLDLGPPGISEFTKPSGQTEREPKPGPSHNQAANDIVNPRSEQKVII 123
Query: 181 LEEGSLLYTESDPLETQNQSSEDSETELLSNLGESAALADDQAIEEDCWLDHPYFQSLNQ 240
LEEGSLLYTESDPLETQNQSSEDSETELLSNLGESAALADDQAIEEDCWLDHPYFQSLNQ
Sbjct: 124 LEEGSLLYTESDPLETQNQSSEDSETELLSNLGESAALADDQAIEEDCWLDHPYFQSLNQ 183
Query: 241 QPREITNQVVPQERQPEAELGRLLFQHEFPGPAFPRPEPQQGGISGPSSPQPAHPLGEFE 300
QPREITNQVVPQERQPEAELGRLLFQHEFPGPAFPRPEPQQGGISGPSSPQPAHPLGEFE
Sbjct: 184 QPREITNQVVPQERQPEAELGRLLFQHEFPGPAFPRPEPQQGGISGPSSPQPAHPLGEFE 243
Query: 301 DQQLASDDEEPGPAFPMQESQEPNLENIWGQEAAEVDQELVELLVKETEARFPDVANGFI 360
DQQLASDDEEPGPAFPMQESQEPNLENIWGQEAAEVDQELVELLVKETEARFPDVANGFI
Sbjct: 244 DQQLASDDEEPGPAFPMQESQEPNLENIWGQEAAEVDQELVELLVKETEARFPDVANGFI 303
Query: 361 EEIIHFKNYYDLNVLCNFLLENPDYPKREDRIIINPSSSLLASQDETKLPKIDFFDYSKL 420
EEIIHFKNYYDLNVLCNFLLENPDYPKREDRIIINPSSSLLASQDETKLPKIDFFDYSKL
Sbjct: 304 EEIIHFKNYYDLNVLCNFLLENPDYPKREDRIIINPSSSLLASQDETKLPKIDFFDYSKL 363
Query: 421 TPLDQRCFIQAADLLMADFKVLSSQDIKWALHELKGHYAITRKALSDAIKKWQELSPETS 480
TPLDQRCFIQAADLLMADFKVLSSQDIKWALHELKGHYAITRKALSDAIKKWQELSPETS
Sbjct: 364 TPLDQRCFIQAADLLMADFKVLSSQDIKWALHELKGHYAITRKALSDAIKKWQELSPETS 423
Query: 481 GKRKKRKQMNQYSYIDFKFEQGDIKIEKRMFFLENKRRHCRSYDRRALLPAVQQEQEFYE 540
GKRKKRKQMNQYSYIDFKFEQGDIKIEKRMFFLENKRRHCRSYDRRALLPAVQQEQEFYE
Sbjct: 424 GKRKKRKQMNQYSYIDFKFEQGDIKIEKRMFFLENKRRHCRSYDRRALLPAVQQEQEFYE 483
Query: 541 QKIKEMAEHEDFLLALQMNEEQYQKDGQLIECRCCYGEFPFEELTQCADAHLFCKECLIR 600
QKIKEMAEHEDFLLALQMNEEQYQKDGQLIECRCCYGEFPFEELTQCADAHLFCKECLIR
Sbjct: 484 QKIKEMAEHEDFLLALQMNEEQYQKDGQLIECRCCYGEFPFEELTQCADAHLFCKECLIR 543
Query: 601 YAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKYYERKAEEEVAAAYADELV 660
YAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKYYERKAEEEVAAAYADELV
Sbjct: 544 YAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKYYERKAEEEVAAAYADELV 603
Query: 661 RCPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNGLTCEELAEKDDIKYRTSI 720
RCPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNGLTCEELAEKDDIKYRTSI
Sbjct: 604 RCPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNGLTCEELAEKDDIKYRTSI 663
Query: 721 EEKMTAARIRKCHKCGTGLIKSEGCNRMSCRCGAQMCYLCRVSINGYDHFCQHPRSPGAP 780
EEKMTAARIRKCHKCGTGLIKSEGCNRMSCRCGAQMCYLCRVSINGYDHFCQHPRSPGAP
Sbjct: 664 EEKMTAARIRKCHKCGTGLIKSEGCNRMSCRCGAQMCYLCRVSINGYDHFCQHPRSPGAP 723
Query: 781 CQECSRCSLWTDPTEDDEKLIEEIQKEAEEEQKRKNGENTFKRIGPPLEKPVEKVQRVEA 840
CQECSRCSLWTDPTEDDEKLIEEIQKEAEEEQKRKNGENTFKRIGPPLEKPVEKVQRVEA
Sbjct: 724 CQECSRCSLWTDPTEDDEKLIEEIQKEAEEEQKRKNGENTFKRIGPPLEKPVEKVQRVEA 783
Query: 841 LPRPVPQNLPQPQMPPYAFAHPPFPLPPVRPVFNNFPLNMGPIPAPYVPPLPNVRVNYDF 900
LPRPVPQNLPQPQMPPYAFAHPPFPLPPVRPVFNNFPLNMGPIPAPYVPPLPNVRVNYDF
Sbjct: 784 LPRPVPQNLPQPQMPPYAFAHPPFPLPPVRPVFNNFPLNMGPIPAPYVPPLPNVRVNYDF 843
Query: 901 GPIHMPLEHNLPMHFGPQPRHRF 923
GPIHMPLEHNLPMHFGPQPRHRF
Sbjct: 844 GPIHMPLEHNLPMHFGPQPRHRF 866
>gi|38045938 ring finger protein 144 [Homo sapiens]
Length = 292
Score = 83.2 bits (204), Expect = 1e-15
Identities = 57/207 (27%), Positives = 93/207 (44%), Gaps = 14/207 (6%)
Query: 569 LIECRCCYGEFPFEELTQCADAH-LFCKECLIRYAQEAVFGSGKLELSCMEGSCTCS--F 625
L+ C+ C GE+P E++T A +FC CL +Y + + + +SC + +C
Sbjct: 17 LVSCKLCLGEYPVEQMTTIAQCQCIFCTLCLKQYVELLIKEGLETAISCPDAACPKQGHL 76
Query: 626 PTSELEKVLPQTILYKYYERKAEEEVAAAYADELVRCPSCSFPALLDSDVKRFSCPNP-- 683
+E+E ++ I+ +Y + + E EV + CP+ + A+ P P
Sbjct: 77 QENEIECMVAAEIMQRYKKLQFEREV--LFDPCRTWCPASTCQAVCQLQDVGLQTPQPVQ 134
Query: 684 --HCRKETCRKCQGLWKEHNGLTCEELAEKDDIKYRTSIEEKMTA--ARIRKCHKCGTGL 739
CR E C C+ W H G C E + TS KM A I++C KC +
Sbjct: 135 CKACRMEFCSTCKASW--HPGQGCPETMPITFLPGETSAAFKMEEDDAPIKRCPKCKVYI 192
Query: 740 IKSEGCNRMSCR-CGAQMCYLCRVSIN 765
+ EGC +M C+ C C+ C S++
Sbjct: 193 ERDEGCAQMMCKNCKHAFCWYCLESLD 219
>gi|5454168 RanBP-type and C3HC4-type zinc finger containing 1
isoform 1 [Homo sapiens]
Length = 468
Score = 70.1 bits (170), Expect = 9e-12
Identities = 68/296 (22%), Positives = 119/296 (40%), Gaps = 56/296 (18%)
Query: 524 DRRALLPAVQQEQEFYEQKIKEMAEHEDFLLALQMNEEQYQKDGQLIECRCCYGEF-PFE 582
+ RA L ++ Y+Q+ K+ + ++L +Q+++ + + EC CY P E
Sbjct: 193 EERARLAGEEEALRQYQQR-KQQQQEGNYLQHVQLDQRSLVLNTEPAECPVCYSVLAPGE 251
Query: 583 ELTQCADAHLFCKECLIRYAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKY 642
+ H FC+ECL Q + S + E+SC T S LE+ + + +
Sbjct: 252 AVVLRECLHTFCRECL----QGTIRNSQEAEVSCPFIDNTYSCSGKLLEREIKALLTPED 307
Query: 643 YERK-------AEEEVAAAYADELVRCPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQG 695
Y+R AE A +Y + P C + DV F+C P C C C+
Sbjct: 308 YQRFLDLGISIAENRSAFSYH---CKTPDCKGWCFFEDDVNEFTC--PVCFHVNCLLCKA 362
Query: 696 LWKEHNGLTCEELAEKDDIKYRTSIEEKMTAARIR---------KCHKCGTGLIKSEGCN 746
+ H + C+E E ++ + + + T ++ +C +C + K +GC+
Sbjct: 363 I---HEQMNCKEYQEDLALRAQNDVAARQTTEMLKVMLQQGEAMRCPQCQIVVQKKDGCD 419
Query: 747 RMSCR-CGAQMCYL-----------------CRVSINGYDHFCQHPRSPGAPCQEC 784
+ C C ++C++ CR +NG C HP CQ C
Sbjct: 420 WIRCTVCHTEICWVTKGPRWGPGGPGDTSGGCRCRVNGIP--C-HP-----SCQNC 467
>gi|144953898 RanBP-type and C3HC4-type zinc finger containing 1
isoform 2 [Homo sapiens]
Length = 510
Score = 70.1 bits (170), Expect = 9e-12
Identities = 68/296 (22%), Positives = 119/296 (40%), Gaps = 56/296 (18%)
Query: 524 DRRALLPAVQQEQEFYEQKIKEMAEHEDFLLALQMNEEQYQKDGQLIECRCCYGEF-PFE 582
+ RA L ++ Y+Q+ K+ + ++L +Q+++ + + EC CY P E
Sbjct: 235 EERARLAGEEEALRQYQQR-KQQQQEGNYLQHVQLDQRSLVLNTEPAECPVCYSVLAPGE 293
Query: 583 ELTQCADAHLFCKECLIRYAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKY 642
+ H FC+ECL Q + S + E+SC T S LE+ + + +
Sbjct: 294 AVVLRECLHTFCRECL----QGTIRNSQEAEVSCPFIDNTYSCSGKLLEREIKALLTPED 349
Query: 643 YERK-------AEEEVAAAYADELVRCPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQG 695
Y+R AE A +Y + P C + DV F+C P C C C+
Sbjct: 350 YQRFLDLGISIAENRSAFSYH---CKTPDCKGWCFFEDDVNEFTC--PVCFHVNCLLCKA 404
Query: 696 LWKEHNGLTCEELAEKDDIKYRTSIEEKMTAARIR---------KCHKCGTGLIKSEGCN 746
+ H + C+E E ++ + + + T ++ +C +C + K +GC+
Sbjct: 405 I---HEQMNCKEYQEDLALRAQNDVAARQTTEMLKVMLQQGEAMRCPQCQIVVQKKDGCD 461
Query: 747 RMSCR-CGAQMCYL-----------------CRVSINGYDHFCQHPRSPGAPCQEC 784
+ C C ++C++ CR +NG C HP CQ C
Sbjct: 462 WIRCTVCHTEICWVTKGPRWGPGGPGDTSGGCRCRVNGIP--C-HP-----SCQNC 509
>gi|35493801 ring finger protein 19 [Homo sapiens]
Length = 838
Score = 69.3 bits (168), Expect = 2e-11
Identities = 62/243 (25%), Positives = 98/243 (40%), Gaps = 38/243 (15%)
Query: 567 GQLIECRCC---YGEFPFEELTQCADAHLFCKECLIRYAQEAVFGSGKLELSCMEGSCTC 623
G IEC C + + F ++ C H C +CL +Y + + S ++ +SC E CT
Sbjct: 127 GDFIECPLCLLRHSKDRFPDIMTCH--HRSCVDCLRQYLRIEISES-RVNISCPE--CTE 181
Query: 624 SFPTSELEKVLPQTILYKYYERKAEEEVAAAYAD-ELVRCPSCSFPALLD--SDVKRFSC 680
F ++ +L +L + YE A D P C + + + + +C
Sbjct: 182 RFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTC 241
Query: 681 PNPHCRKETCRKCQGLWKEHNGLTCEELAEK--DDIKYRT--------SIEEKMTAARIR 730
C E C C+ +W H TC+ ++ ++ RT S E A I+
Sbjct: 242 GREGCGTEFCYHCKQIW--HPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIK 299
Query: 731 KCHKCGTGLIKSE--GCNRMSCR-CGAQMCYLCRVSINGYDHFCQHPRSPGAPCQECSRC 787
C +C +IK CN M+C CG + C+LC I+ H SP S C
Sbjct: 300 PCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDL-----HYLSP-------SGC 347
Query: 788 SLW 790
+ W
Sbjct: 348 TFW 350
>gi|35493782 ring finger protein 19 [Homo sapiens]
Length = 838
Score = 69.3 bits (168), Expect = 2e-11
Identities = 62/243 (25%), Positives = 98/243 (40%), Gaps = 38/243 (15%)
Query: 567 GQLIECRCC---YGEFPFEELTQCADAHLFCKECLIRYAQEAVFGSGKLELSCMEGSCTC 623
G IEC C + + F ++ C H C +CL +Y + + S ++ +SC E CT
Sbjct: 127 GDFIECPLCLLRHSKDRFPDIMTCH--HRSCVDCLRQYLRIEISES-RVNISCPE--CTE 181
Query: 624 SFPTSELEKVLPQTILYKYYERKAEEEVAAAYAD-ELVRCPSCSFPALLD--SDVKRFSC 680
F ++ +L +L + YE A D P C + + + + +C
Sbjct: 182 RFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTC 241
Query: 681 PNPHCRKETCRKCQGLWKEHNGLTCEELAEK--DDIKYRT--------SIEEKMTAARIR 730
C E C C+ +W H TC+ ++ ++ RT S E A I+
Sbjct: 242 GREGCGTEFCYHCKQIW--HPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIK 299
Query: 731 KCHKCGTGLIKSE--GCNRMSCR-CGAQMCYLCRVSINGYDHFCQHPRSPGAPCQECSRC 787
C +C +IK CN M+C CG + C+LC I+ H SP S C
Sbjct: 300 PCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDL-----HYLSP-------SGC 347
Query: 788 SLW 790
+ W
Sbjct: 348 TFW 350
>gi|34577102 ring finger protein 14 isoform 1 [Homo sapiens]
Length = 474
Score = 63.9 bits (154), Expect = 6e-10
Identities = 72/287 (25%), Positives = 115/287 (40%), Gaps = 47/287 (16%)
Query: 532 VQQEQEFYEQKIKEMAEHEDFLLA-LQMNEEQYQK--DGQLIECRCCYGEFPFEELTQCA 588
V QE+ E+ ++++ + + L ++ Q K + +L C C+ E E
Sbjct: 177 VDQEEIVDERAVQDVESLSNLIQEILDFDQAQQIKCFNSKLFLCSICFCEKLGSECMYFL 236
Query: 589 DA-HLFCKECLIRYAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKYYERKA 647
+ H++CK CL Y + + L+C E C S T K L + L+ Y+R
Sbjct: 237 ECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCP-SVATPGQVKELVEAELFARYDRLL 295
Query: 648 EEEVAAAYADELVRCPS--CSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNGLTC 705
+ AD +V CP C P + + C + C C C+ + H C
Sbjct: 296 LQSSLDLMAD-VVYCPRPCCQLPVMQEPGCTMGICSS--CNFAFCTLCRLTY--HGVSPC 350
Query: 706 EELAEK-----------DDIKYRT------------SIEEKMTAARIRK----CHKCGTG 738
+ AEK D+ R ++EE + + K C CGT
Sbjct: 351 KVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESKEWLEKNSKSCPCCGTP 410
Query: 739 LIKSEGCNRMSCR-CGAQMCYLCRVSI---NGYDHFCQHPRSPGAPC 781
+ K +GCN+M+C C C++C S+ N Y HF PG+PC
Sbjct: 411 IEKLDGCNKMTCTGCMQYFCWICMGSLSRANPYKHF----NDPGSPC 453
>gi|34577100 ring finger protein 14 isoform 1 [Homo sapiens]
Length = 474
Score = 63.9 bits (154), Expect = 6e-10
Identities = 72/287 (25%), Positives = 115/287 (40%), Gaps = 47/287 (16%)
Query: 532 VQQEQEFYEQKIKEMAEHEDFLLA-LQMNEEQYQK--DGQLIECRCCYGEFPFEELTQCA 588
V QE+ E+ ++++ + + L ++ Q K + +L C C+ E E
Sbjct: 177 VDQEEIVDERAVQDVESLSNLIQEILDFDQAQQIKCFNSKLFLCSICFCEKLGSECMYFL 236
Query: 589 DA-HLFCKECLIRYAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKYYERKA 647
+ H++CK CL Y + + L+C E C S T K L + L+ Y+R
Sbjct: 237 ECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCP-SVATPGQVKELVEAELFARYDRLL 295
Query: 648 EEEVAAAYADELVRCPS--CSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNGLTC 705
+ AD +V CP C P + + C + C C C+ + H C
Sbjct: 296 LQSSLDLMAD-VVYCPRPCCQLPVMQEPGCTMGICSS--CNFAFCTLCRLTY--HGVSPC 350
Query: 706 EELAEK-----------DDIKYRT------------SIEEKMTAARIRK----CHKCGTG 738
+ AEK D+ R ++EE + + K C CGT
Sbjct: 351 KVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESKEWLEKNSKSCPCCGTP 410
Query: 739 LIKSEGCNRMSCR-CGAQMCYLCRVSI---NGYDHFCQHPRSPGAPC 781
+ K +GCN+M+C C C++C S+ N Y HF PG+PC
Sbjct: 411 IEKLDGCNKMTCTGCMQYFCWICMGSLSRANPYKHF----NDPGSPC 453
>gi|34577098 ring finger protein 14 isoform 1 [Homo sapiens]
Length = 474
Score = 63.9 bits (154), Expect = 6e-10
Identities = 72/287 (25%), Positives = 115/287 (40%), Gaps = 47/287 (16%)
Query: 532 VQQEQEFYEQKIKEMAEHEDFLLA-LQMNEEQYQK--DGQLIECRCCYGEFPFEELTQCA 588
V QE+ E+ ++++ + + L ++ Q K + +L C C+ E E
Sbjct: 177 VDQEEIVDERAVQDVESLSNLIQEILDFDQAQQIKCFNSKLFLCSICFCEKLGSECMYFL 236
Query: 589 DA-HLFCKECLIRYAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKYYERKA 647
+ H++CK CL Y + + L+C E C S T K L + L+ Y+R
Sbjct: 237 ECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCP-SVATPGQVKELVEAELFARYDRLL 295
Query: 648 EEEVAAAYADELVRCPS--CSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNGLTC 705
+ AD +V CP C P + + C + C C C+ + H C
Sbjct: 296 LQSSLDLMAD-VVYCPRPCCQLPVMQEPGCTMGICSS--CNFAFCTLCRLTY--HGVSPC 350
Query: 706 EELAEK-----------DDIKYRT------------SIEEKMTAARIRK----CHKCGTG 738
+ AEK D+ R ++EE + + K C CGT
Sbjct: 351 KVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESKEWLEKNSKSCPCCGTP 410
Query: 739 LIKSEGCNRMSCR-CGAQMCYLCRVSI---NGYDHFCQHPRSPGAPC 781
+ K +GCN+M+C C C++C S+ N Y HF PG+PC
Sbjct: 411 IEKLDGCNKMTCTGCMQYFCWICMGSLSRANPYKHF----NDPGSPC 453
>gi|34577096 ring finger protein 14 isoform 2 [Homo sapiens]
Length = 348
Score = 63.9 bits (154), Expect = 6e-10
Identities = 72/287 (25%), Positives = 115/287 (40%), Gaps = 47/287 (16%)
Query: 532 VQQEQEFYEQKIKEMAEHEDFLLA-LQMNEEQYQK--DGQLIECRCCYGEFPFEELTQCA 588
V QE+ E+ ++++ + + L ++ Q K + +L C C+ E E
Sbjct: 51 VDQEEIVDERAVQDVESLSNLIQEILDFDQAQQIKCFNSKLFLCSICFCEKLGSECMYFL 110
Query: 589 DA-HLFCKECLIRYAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKYYERKA 647
+ H++CK CL Y + + L+C E C S T K L + L+ Y+R
Sbjct: 111 ECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCP-SVATPGQVKELVEAELFARYDRLL 169
Query: 648 EEEVAAAYADELVRCPS--CSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNGLTC 705
+ AD +V CP C P + + C + C C C+ + H C
Sbjct: 170 LQSSLDLMAD-VVYCPRPCCQLPVMQEPGCTMGICSS--CNFAFCTLCRLTY--HGVSPC 224
Query: 706 EELAEK-----------DDIKYRT------------SIEEKMTAARIRK----CHKCGTG 738
+ AEK D+ R ++EE + + K C CGT
Sbjct: 225 KVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESKEWLEKNSKSCPCCGTP 284
Query: 739 LIKSEGCNRMSCR-CGAQMCYLCRVSI---NGYDHFCQHPRSPGAPC 781
+ K +GCN+M+C C C++C S+ N Y HF PG+PC
Sbjct: 285 IEKLDGCNKMTCTGCMQYFCWICMGSLSRANPYKHF----NDPGSPC 327
>gi|4757762 ring finger protein 14 isoform 1 [Homo sapiens]
Length = 474
Score = 63.9 bits (154), Expect = 6e-10
Identities = 72/287 (25%), Positives = 115/287 (40%), Gaps = 47/287 (16%)
Query: 532 VQQEQEFYEQKIKEMAEHEDFLLA-LQMNEEQYQK--DGQLIECRCCYGEFPFEELTQCA 588
V QE+ E+ ++++ + + L ++ Q K + +L C C+ E E
Sbjct: 177 VDQEEIVDERAVQDVESLSNLIQEILDFDQAQQIKCFNSKLFLCSICFCEKLGSECMYFL 236
Query: 589 DA-HLFCKECLIRYAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKYYERKA 647
+ H++CK CL Y + + L+C E C S T K L + L+ Y+R
Sbjct: 237 ECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCP-SVATPGQVKELVEAELFARYDRLL 295
Query: 648 EEEVAAAYADELVRCPS--CSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNGLTC 705
+ AD +V CP C P + + C + C C C+ + H C
Sbjct: 296 LQSSLDLMAD-VVYCPRPCCQLPVMQEPGCTMGICSS--CNFAFCTLCRLTY--HGVSPC 350
Query: 706 EELAEK-----------DDIKYRT------------SIEEKMTAARIRK----CHKCGTG 738
+ AEK D+ R ++EE + + K C CGT
Sbjct: 351 KVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESKEWLEKNSKSCPCCGTP 410
Query: 739 LIKSEGCNRMSCR-CGAQMCYLCRVSI---NGYDHFCQHPRSPGAPC 781
+ K +GCN+M+C C C++C S+ N Y HF PG+PC
Sbjct: 411 IEKLDGCNKMTCTGCMQYFCWICMGSLSRANPYKHF----NDPGSPC 453
>gi|188219577 ring finger protein 19B isoform a [Homo sapiens]
Length = 732
Score = 63.5 bits (153), Expect = 8e-10
Identities = 56/237 (23%), Positives = 96/237 (40%), Gaps = 33/237 (13%)
Query: 570 IECRCCYGEFPFEELTQCADA-HLFCKECLIRYAQEAVFGSGKLELSCMEGSCTCSFPTS 628
+EC C P E + H C++CL Y + + S ++ +SC E C+
Sbjct: 117 VECPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISES-RVPISCPE--CSERLNPH 173
Query: 629 ELEKVLPQT-ILYKYYERKAEEEVAAAYADELVRCPSCSFPALLD--SDVKRFSCPNPHC 685
++ +L +++KY E +A+ P C + + + + +C C
Sbjct: 174 DIRLLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREGC 233
Query: 686 RKETCRKCQGLWKEHNGLTCEELAEK--DDIKYRTSI-------EEKMTAARIRKCHKCG 736
+ E C C+ +W H TC+ ++ ++ RT +E A I+ C +C
Sbjct: 234 QTEFCYHCKQIW--HPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGPADDIKPCPRCS 291
Query: 737 TGLIKSE--GCNRMSCR-CGAQMCYLCRVSINGYDHFCQHPRSPGAPCQECSRCSLW 790
+IK CN M+C CG + C+LC I+ H SP S C+ W
Sbjct: 292 AYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDL-----HYLSP-------SGCTFW 336
>gi|188219579 ring finger protein 19B isoform b [Homo sapiens]
Length = 587
Score = 62.4 bits (150), Expect = 2e-09
Identities = 55/236 (23%), Positives = 96/236 (40%), Gaps = 32/236 (13%)
Query: 570 IECRCCYGEFPFEELTQCADA-HLFCKECLIRYAQEAVFGSGKLELSCMEGSCTCSFPTS 628
+EC C P E + H C++CL Y + + S ++ +SC E C+
Sbjct: 117 VECPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISES-RVPISCPE--CSERLNPH 173
Query: 629 ELEKVLPQT-ILYKYYERKAEEEVAAAYADELVRCPSCSFPALLD--SDVKRFSCPNPHC 685
++ +L +++KY E +A+ P C + + + + +C C
Sbjct: 174 DIRLLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREGC 233
Query: 686 RKETCRKCQGLWKEHNGLTCEELAEK--DDIKYRT------SIEEKMTAARIRKCHKCGT 737
+ E C C+ +W H TC+ ++ ++ RT S ++ I+ C +C
Sbjct: 234 QTEFCYHCKQIW--HPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGPDDIKPCPRCSA 291
Query: 738 GLIKSE--GCNRMSCR-CGAQMCYLCRVSINGYDHFCQHPRSPGAPCQECSRCSLW 790
+IK CN M+C CG + C+LC I+ H SP S C+ W
Sbjct: 292 YIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDL-----HYLSP-------SGCTFW 335
>gi|187761373 ariadne ubiquitin-conjugating enzyme E2 binding
protein homolog 1 [Homo sapiens]
Length = 557
Score = 62.4 bits (150), Expect = 2e-09
Identities = 64/268 (23%), Positives = 100/268 (37%), Gaps = 38/268 (14%)
Query: 557 QMNEEQYQKDGQLIECRCCYGEFPFEELTQCADAHLFCKECLIRYAQEAVFGSGKLE-LS 615
QMN +D + C+ CY +P T H FC +C Y + G + +S
Sbjct: 174 QMNTRSSAQD---MPCQICYLNYPNSYFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTIS 230
Query: 616 CMEGSCTCSFPTSELEKVLPQT-ILYKYYERKAEEEVAAAYADELVRCPSCSFPALLD-S 673
C C + + +++ + + KY V + P C +
Sbjct: 231 CPAHGCDILVDDNTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYP 290
Query: 674 DVKRFSCPNPHCRKETCRKCQGLWKEHNGLTCEELAE---KDDIKYRTSIEEKMTAARIR 730
D K C C ++ C C W H+ + C+ L + K D TS AA +
Sbjct: 291 DAKPVRCK---CGRQFCFNCGENW--HDPVKCKWLKKWIKKCDDDSETS---NWIAANTK 342
Query: 731 KCHKCGTGLIKSEGCNRMSCR---CGAQMCYLCRVSINGYDHFCQHPRSP-GAPCQECSR 786
+C KC + K GCN M CR C A+ C++ C P P G+ C+R
Sbjct: 343 ECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWV-----------CLGPWEPHGSAWYNCNR 391
Query: 787 CSLWTDPTEDDEKLIEEIQKEAEEEQKR 814
+ EDD K + Q+ + +R
Sbjct: 392 YN------EDDAKAARDAQERSRAALQR 413
Score = 40.0 bits (92), Expect = 0.010
Identities = 25/90 (27%), Positives = 32/90 (35%), Gaps = 3/90 (3%)
Query: 648 EEEVAAAYADELVRCPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNG--LTC 705
+ E + A CP C D C N +C+ E C C G W+ H C
Sbjct: 330 DSETSNWIAANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLGPWEPHGSAWYNC 389
Query: 706 EELAEKDDIKYRTSIEEKMTAARIRKCHKC 735
E DD K +E+ AA R C
Sbjct: 390 NRYNE-DDAKAARDAQERSRAALQRYLFYC 418
>gi|5453557 ariadne homolog 2 [Homo sapiens]
Length = 493
Score = 61.6 bits (148), Expect = 3e-09
Identities = 46/193 (23%), Positives = 75/193 (38%), Gaps = 9/193 (4%)
Query: 572 CRCCYGEFPFEELTQCADAHLFCKECLIRYAQEAVFGSGKLELSCMEGSCTCSFPTSELE 631
C C E L A H FC+ C ++ V + +SCM C P +
Sbjct: 139 CAVCMQFVRKENLLSLACQHQFCRSCWEQHCSVLVKDGVGVGVSCMAQDCPLRTPEDFVF 198
Query: 632 KVLPQTILYKYYERKAEEEVAAAYADELVRCPSCSFPALL---DSDVKRFSCPNPHCRKE 688
+LP L + Y R + ++ +L CP P ++ + +R C C +
Sbjct: 199 PLLPNEELREKYRRYLFRDYVESHY-QLQLCPGADCPMVIRVQEPRARRVQC--NRCNEV 255
Query: 689 TCRKCQGLWKEHNGLTCEELAEKDDIKYRTSIEEKMTAARIRKCHKCGTGLIKSEGCNRM 748
C KC+ ++ H C + + S +A + C KC + K+ GCN M
Sbjct: 256 FCFKCRQMY--HAPTDCATIRKWLTKCADDSETANYISAHTKDCPKCNICIEKNGGCNHM 313
Query: 749 SC-RCGAQMCYLC 760
C +C C++C
Sbjct: 314 QCSKCKHDFCWMC 326
Score = 30.8 bits (68), Expect = 6.1
Identities = 19/77 (24%), Positives = 28/77 (36%), Gaps = 5/77 (6%)
Query: 641 KYYERKAEEEVAAAYADELVR-CPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKE 699
K+ + A++ A Y + CP C+ + C C+ + C C G WK
Sbjct: 275 KWLTKCADDSETANYISAHTKDCPKCNICIEKNGGCNHMQCSK--CKHDFCWMCLGDWKT 332
Query: 700 HNG--LTCEELAEKDDI 714
H C E DI
Sbjct: 333 HGSEYYECSRYKENPDI 349
>gi|22749145 ring finger protein 217 [Homo sapiens]
Length = 275
Score = 58.2 bits (139), Expect = 4e-08
Identities = 46/169 (27%), Positives = 71/169 (42%), Gaps = 29/169 (17%)
Query: 611 KLELSCMEGSCTCSFPTSELEKVLPQTILYKYYERKAEEEVAAAYADELVR-------CP 663
K++L +E C P +E + L +T + Y E+ + Y EL R CP
Sbjct: 2 KVQLGQVEIKC----PITECFEFLEETTVV--YNLTHEDSIKYKYFLELGRIDSSTKPCP 55
Query: 664 SCS----------FPALLDSDVK-RFSCPNPHCRKETCRKCQGLWKEHNGLTCEELAEKD 712
C P S+ K + CP C+ C KC W H G+ C+E + D
Sbjct: 56 QCKHFTTFKKKGHIPTPSRSESKYKIQCPT--CQFVWCFKCHSPW--HEGVNCKEYKKGD 111
Query: 713 DIKYRTSIEEKMTAARIRKCHKCGTGLIKSEGCNRMSC-RCGAQMCYLC 760
+ + E + +KC KC + ++EGC+ M+C +C CY C
Sbjct: 112 KLLRHWASEIEHGQRNAQKCPKCKIHIQRTEGCDHMTCSQCNTNFCYRC 160
>gi|50284696 IBR domain containing 2 [Homo sapiens]
Length = 303
Score = 54.7 bits (130), Expect = 4e-07
Identities = 55/225 (24%), Positives = 93/225 (41%), Gaps = 37/225 (16%)
Query: 569 LIECRCCYGEFPFEELTQCADAH-LFCKECLIRYAQEAVFGSGKLELSCMEGSCTC--SF 625
LI C+ C E +++T + +FC CL +Y Q A+ ++C + C +
Sbjct: 27 LITCKLCLCEQSLDKMTTLQECQCIFCTACLKQYMQLAIREGCGSPITCPDMVCLNHGTL 86
Query: 626 PTSELEKVLPQTILYKYYERKAEEEVA-------AAYADELVRCPSCSF----PALLDSD 674
+E+ ++P Y K E EV AD CP S P L++
Sbjct: 87 QEAEIACLVPVDQFQLYQRLKFEREVHLDPYRTWCPVADCQTVCPVASSDPGQPVLVE-- 144
Query: 675 VKRFSCPNPHCRKETCRKCQGLWKEHNGLTCEE-----LAEKDDIKYRTSIEEKMTAARI 729
CP+ C + C C+ W H ++C + L + + T E A I
Sbjct: 145 -----CPS--CHLKFCSCCKDAW--HAEVSCRDSQPIVLPTEHRALFGTDAE-----API 190
Query: 730 RKCHKCGTGLIKSEGCNRMSCR-CGAQMCYLCRVSINGYDHFCQH 773
++C C + ++EGC +M C+ C C+ C +++ D F +H
Sbjct: 191 KQCPVCRVYIERNEGCAQMMCKNCKHTFCWYCLQNLDN-DIFLRH 234
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 50.1 bits (118), Expect = 1e-05
Identities = 30/98 (30%), Positives = 50/98 (51%), Gaps = 7/98 (7%)
Query: 795 EDDEKLIEEIQKEAEEEQKRKNGENTFKRIGPPLEKPVEKVQRVEALPRPV--PQNLPQP 852
+ ++KL +E +++ EEE+K K GE +R P + + + P P+ P P P
Sbjct: 356 KQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPP 415
Query: 853 QMPPYAFAHPPFPLPPVRPVFNNFPLNMGPIPAPYVPP 890
+PP + + PP PP P P++ P+P+P PP
Sbjct: 416 PLPPPSTSPPPPLCPPPPP-----PVSPPPLPSPPPPP 448
>gi|157168329 formin 1 [Homo sapiens]
Length = 1196
Score = 44.7 bits (104), Expect = 4e-04
Identities = 26/56 (46%), Positives = 29/56 (51%), Gaps = 5/56 (8%)
Query: 842 PRPVPQNL----PQPQMPPYAFAHPPFPLPPVRPVFNNFPLNMGPIPAPYVPPLPN 893
P P+P L P P MPP + A PP P PP P P + GP P P PPLPN
Sbjct: 655 PPPLPSGLGSLSPAPPMPPVS-AGPPLPPPPPPPPPLPPPSSAGPPPPPPPPPLPN 709
Score = 37.0 bits (84), Expect = 0.085
Identities = 24/64 (37%), Positives = 28/64 (43%), Gaps = 5/64 (7%)
Query: 831 PVEKVQRVEALPRPVPQNLPQPQMPPYAFAHPPFPLPPVRPVFNNFPLNMGPIPAPYVPP 890
P+ V LP P P P P +PP + A PP P PP P N P P P PP
Sbjct: 670 PMPPVSAGPPLPPPPP---PPPPLPPPSSAGPPPPPPP--PPLPNSPAPPNPGGPPPAPP 724
Query: 891 LPNV 894
P +
Sbjct: 725 PPGL 728
>gi|169790973 parkin isoform 3 [Homo sapiens]
Length = 316
Score = 44.3 bits (103), Expect = 5e-04
Identities = 31/110 (28%), Positives = 39/110 (35%), Gaps = 25/110 (22%)
Query: 593 FCKECLIRYAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKYYERKAEEEVA 652
FC+EC Y EG C+ F S T Y+ ER AE+
Sbjct: 215 FCRECKEAYH---------------EGECSAVFEASGTT-----TQAYRVDERAAEQARW 254
Query: 653 AAYADELVR-----CPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLW 697
A + E ++ CP C P + CP P CR E C C W
Sbjct: 255 EAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEW 304
Score = 42.4 bits (98), Expect = 0.002
Identities = 44/198 (22%), Positives = 75/198 (37%), Gaps = 23/198 (11%)
Query: 586 QCADAHLFCKECLIRYAQEAVFGSGKLELSCMEGS--CTCSFPTSELEKVLPQTIL---- 639
QC H+ C +C Y + + + S C P S ++++ IL
Sbjct: 103 QCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQ 162
Query: 640 YKYYERKAEEEVAAAYADELVRCPSCSFPALLDSDVKRFSCPNPH---CRKETCRKCQGL 696
Y Y++ EE L P C L + D ++ +C + C CR+C+
Sbjct: 163 YNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEA 222
Query: 697 WKEH--------NGLTCE--ELAEKDDIKYRTSIEEKMTAARIRK-CHKCGTGLIKSEGC 745
+ E +G T + + E+ + R K T + K C +C + K+ GC
Sbjct: 223 YHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGC 282
Query: 746 NRMSC---RCGAQMCYLC 760
M C +C + C+ C
Sbjct: 283 MHMKCPQPQCRLEWCWNC 300
>gi|169790971 parkin isoform 2 [Homo sapiens]
Length = 437
Score = 44.3 bits (103), Expect = 5e-04
Identities = 31/110 (28%), Positives = 39/110 (35%), Gaps = 25/110 (22%)
Query: 593 FCKECLIRYAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKYYERKAEEEVA 652
FC+EC Y EG C+ F S T Y+ ER AE+
Sbjct: 336 FCRECKEAYH---------------EGECSAVFEASGTT-----TQAYRVDERAAEQARW 375
Query: 653 AAYADELVR-----CPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLW 697
A + E ++ CP C P + CP P CR E C C W
Sbjct: 376 EAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEW 425
Score = 42.4 bits (98), Expect = 0.002
Identities = 44/198 (22%), Positives = 75/198 (37%), Gaps = 23/198 (11%)
Query: 586 QCADAHLFCKECLIRYAQEAVFGSGKLELSCMEGS--CTCSFPTSELEKVLPQTIL---- 639
QC H+ C +C Y + + + S C P S ++++ IL
Sbjct: 224 QCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQ 283
Query: 640 YKYYERKAEEEVAAAYADELVRCPSCSFPALLDSDVKRFSCPNPH---CRKETCRKCQGL 696
Y Y++ EE L P C L + D ++ +C + C CR+C+
Sbjct: 284 YNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEA 343
Query: 697 WKEH--------NGLTCE--ELAEKDDIKYRTSIEEKMTAARIRK-CHKCGTGLIKSEGC 745
+ E +G T + + E+ + R K T + K C +C + K+ GC
Sbjct: 344 YHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGC 403
Query: 746 NRMSC---RCGAQMCYLC 760
M C +C + C+ C
Sbjct: 404 MHMKCPQPQCRLEWCWNC 421
>gi|169790969 parkin isoform 1 [Homo sapiens]
Length = 465
Score = 44.3 bits (103), Expect = 5e-04
Identities = 31/110 (28%), Positives = 39/110 (35%), Gaps = 25/110 (22%)
Query: 593 FCKECLIRYAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKYYERKAEEEVA 652
FC+EC Y EG C+ F S T Y+ ER AE+
Sbjct: 364 FCRECKEAYH---------------EGECSAVFEASGTT-----TQAYRVDERAAEQARW 403
Query: 653 AAYADELVR-----CPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLW 697
A + E ++ CP C P + CP P CR E C C W
Sbjct: 404 EAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEW 453
Score = 42.4 bits (98), Expect = 0.002
Identities = 44/198 (22%), Positives = 75/198 (37%), Gaps = 23/198 (11%)
Query: 586 QCADAHLFCKECLIRYAQEAVFGSGKLELSCMEGS--CTCSFPTSELEKVLPQTIL---- 639
QC H+ C +C Y + + + S C P S ++++ IL
Sbjct: 252 QCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQ 311
Query: 640 YKYYERKAEEEVAAAYADELVRCPSCSFPALLDSDVKRFSCPNPH---CRKETCRKCQGL 696
Y Y++ EE L P C L + D ++ +C + C CR+C+
Sbjct: 312 YNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEA 371
Query: 697 WKEH--------NGLTCE--ELAEKDDIKYRTSIEEKMTAARIRK-CHKCGTGLIKSEGC 745
+ E +G T + + E+ + R K T + K C +C + K+ GC
Sbjct: 372 YHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGC 431
Query: 746 NRMSC---RCGAQMCYLC 760
M C +C + C+ C
Sbjct: 432 MHMKCPQPQCRLEWCWNC 449
>gi|215820635 protein phosphatase 1, regulatory subunit 13 like
[Homo sapiens]
Length = 828
Score = 43.9 bits (102), Expect = 7e-04
Identities = 33/102 (32%), Positives = 43/102 (42%), Gaps = 18/102 (17%)
Query: 817 GENTFKRIGPPLEKPVEKVQRVEALPRPVPQNLPQPQMPPYAFAHPPFPLP-PVRPVFNN 875
G F R PP +P + P+P PQ+ PQPQ+PP P P P P P
Sbjct: 394 GSPLFTRAPPPKLQP-------QPQPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTW 446
Query: 876 FPLNMG-PIPAPYVPPLPNVR---------VNYDFGPIHMPL 907
P+N G P P + P P + + D GP+ PL
Sbjct: 447 PPVNEGPPKPPTELEPEPEIEGLLTPVLEAGDVDEGPVARPL 488
>gi|63003907 protein phosphatase 1, regulatory subunit 13 like [Homo
sapiens]
Length = 828
Score = 43.9 bits (102), Expect = 7e-04
Identities = 33/102 (32%), Positives = 43/102 (42%), Gaps = 18/102 (17%)
Query: 817 GENTFKRIGPPLEKPVEKVQRVEALPRPVPQNLPQPQMPPYAFAHPPFPLP-PVRPVFNN 875
G F R PP +P + P+P PQ+ PQPQ+PP P P P P P
Sbjct: 394 GSPLFTRAPPPKLQP-------QPQPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTW 446
Query: 876 FPLNMG-PIPAPYVPPLPNVR---------VNYDFGPIHMPL 907
P+N G P P + P P + + D GP+ PL
Sbjct: 447 PPVNEGPPKPPTELEPEPEIEGLLTPVLEAGDVDEGPVARPL 488
>gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3
[Homo sapiens]
Length = 1125
Score = 42.0 bits (97), Expect = 0.003
Identities = 33/107 (30%), Positives = 45/107 (42%), Gaps = 8/107 (7%)
Query: 804 IQKEAEEEQKRKNG-ENTFKRIGPPLEKPVEKVQRVEALPRPVPQNLPQPQMPPYAFAHP 862
I K+ E E + G E + P+ KP+ V +P P P +P PQ+PP+ P
Sbjct: 633 IPKKPENEVAQNGGAETSHTEPVSPIPKPLPVP--VPPIPVPAPITVPPPQVPPHQPGPP 690
Query: 863 ---PFPLPPVRPVFNNFPLNMGPIPAPYVPPLPNVRVNYDFGPIHMP 906
P P P GP P PP P +R F P+H+P
Sbjct: 691 VVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPG--FNPMHLP 735
>gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2
[Homo sapiens]
Length = 1132
Score = 42.0 bits (97), Expect = 0.003
Identities = 33/107 (30%), Positives = 45/107 (42%), Gaps = 8/107 (7%)
Query: 804 IQKEAEEEQKRKNG-ENTFKRIGPPLEKPVEKVQRVEALPRPVPQNLPQPQMPPYAFAHP 862
I K+ E E + G E + P+ KP+ V +P P P +P PQ+PP+ P
Sbjct: 618 IPKKPENEVAQNGGAETSHTEPVSPIPKPLPVP--VPPIPVPAPITVPPPQVPPHQPGPP 675
Query: 863 ---PFPLPPVRPVFNNFPLNMGPIPAPYVPPLPNVRVNYDFGPIHMP 906
P P P GP P PP P +R F P+H+P
Sbjct: 676 VVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPG--FNPMHLP 720
>gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1
[Homo sapiens]
Length = 1147
Score = 42.0 bits (97), Expect = 0.003
Identities = 33/107 (30%), Positives = 45/107 (42%), Gaps = 8/107 (7%)
Query: 804 IQKEAEEEQKRKNG-ENTFKRIGPPLEKPVEKVQRVEALPRPVPQNLPQPQMPPYAFAHP 862
I K+ E E + G E + P+ KP+ V +P P P +P PQ+PP+ P
Sbjct: 633 IPKKPENEVAQNGGAETSHTEPVSPIPKPLPVP--VPPIPVPAPITVPPPQVPPHQPGPP 690
Query: 863 ---PFPLPPVRPVFNNFPLNMGPIPAPYVPPLPNVRVNYDFGPIHMP 906
P P P GP P PP P +R F P+H+P
Sbjct: 691 VVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPG--FNPMHLP 735
>gi|239753435 PREDICTED: hypothetical protein XP_002345651 [Homo
sapiens]
Length = 218
Score = 40.8 bits (94), Expect = 0.006
Identities = 24/66 (36%), Positives = 29/66 (43%), Gaps = 2/66 (3%)
Query: 826 PPLEKPVEKVQRVEALPRPVPQNLPQPQMPPYAFAHPPFPLPPVRPVFNNFPLNMGPIPA 885
PP P K R PRP+P N P+P +PP P PLPP RP PL +
Sbjct: 24 PPPPLPPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKP--PLPPPRPPKPPSPLGLAQSKV 81
Query: 886 PYVPPL 891
P +
Sbjct: 82 TLFPSI 87
Score = 33.5 bits (75), Expect = 0.94
Identities = 20/46 (43%), Positives = 22/46 (47%), Gaps = 3/46 (6%)
Query: 850 PQPQMPPYAFAHPPFPLPPVRPVFNNFPLNMGPIPAPYVPPLPNVR 895
P P +PP PP P P RP+ N P P P P PPLP R
Sbjct: 24 PPPPLPP---RKPPRPPKPPRPLPPNPPRPPLPPPRPPKPPLPPPR 66
>gi|239747993 PREDICTED: hypothetical protein XP_002346504 [Homo
sapiens]
Length = 218
Score = 40.8 bits (94), Expect = 0.006
Identities = 24/66 (36%), Positives = 29/66 (43%), Gaps = 2/66 (3%)
Query: 826 PPLEKPVEKVQRVEALPRPVPQNLPQPQMPPYAFAHPPFPLPPVRPVFNNFPLNMGPIPA 885
PP P K R PRP+P N P+P +PP P PLPP RP PL +
Sbjct: 24 PPPPLPPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKP--PLPPPRPPKPPSPLGLAQSKV 81
Query: 886 PYVPPL 891
P +
Sbjct: 82 TLFPSI 87
Score = 33.5 bits (75), Expect = 0.94
Identities = 20/46 (43%), Positives = 22/46 (47%), Gaps = 3/46 (6%)
Query: 850 PQPQMPPYAFAHPPFPLPPVRPVFNNFPLNMGPIPAPYVPPLPNVR 895
P P +PP PP P P RP+ N P P P P PPLP R
Sbjct: 24 PPPPLPP---RKPPRPPKPPRPLPPNPPRPPLPPPRPPKPPLPPPR 66
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.135 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,800,979
Number of Sequences: 37866
Number of extensions: 2553365
Number of successful extensions: 15792
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 54
Number of HSP's successfully gapped in prelim test: 360
Number of HSP's that attempted gapping in prelim test: 13837
Number of HSP's gapped (non-prelim): 1887
length of query: 923
length of database: 18,247,518
effective HSP length: 112
effective length of query: 811
effective length of database: 14,006,526
effective search space: 11359292586
effective search space used: 11359292586
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.