Guide to the Human Genome
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Name: HLCS Sequence: fasta or formatted (726aa) NCBI GI: 46255045
Description:

holocarboxylase synthetase

Referenced in:

Vitamin Pathways, Coenzymes, and 1-Carbon Metabolism

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             4.1         30           2
 C cysteine            1.5         11           1
 D aspartate           5.2         38           2
 E glutamate           7.7         56           2
 F phenylalanine       2.9         21           1
 G glycine             7.4         54           3
 H histidine           2.9         21           1
 I isoleucine          5.1         37           1
 K lysine              4.7         34           1
 L leucine            12.0         87           3
 M methionine          2.1         15           1
 N asparagine          3.7         27           1
 P proline             5.5         40           2
 Q glutamine           5.0         36           2
 R arginine            5.0         36           2
 S serine              9.0         65           3
 T threonine           4.1         30           2
 V valine              8.4         61           2
 W tryptophan          0.7          5           1
 Y tyrosine            3.0         22           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   holocarboxylase synthetase 
MAP3K13               0.005   mitogen-activated protein kinase kinase kinase 13 [Ho...
WDR43                 0.005   WD repeat domain 43 
ASXL2                 0.005   additional sex combs like 2 
ZNF469                0.005   zinc finger protein 469 
GTF3C4                0.005   general transcription factor IIIC 4 
DDN                   0.005   dendrin 
ZFYVE26               0.005   zinc finger, FYVE domain containing 26 
AFF1                  0.005   myeloid/lymphoid or mixed-lineage leukemia trithorax ...
RYR1                  0.004   skeletal muscle ryanodine receptor isoform 2 
RYR1                  0.004   skeletal muscle ryanodine receptor isoform 1 
TNKS                  0.004   tankyrase, TRF1-interacting ankyrin-related ADP-ribo...
HCLS1                 0.004   hematopoietic cell-specific Lyn substrate 1 
RGAG4                 0.004   retrotransposon gag domain containing 4 
RP1L1                 0.004   retinitis pigmentosa 1-like 1 
ATP11C                0.004   ATPase, class VI, type 11C isoform b 
ATP11C                0.004   ATPase, class VI, type 11C isoform a 
DBF4                  0.004   activator of S phase kinase 
SALL2                 0.004   sal-like 2 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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