Search of human proteins with 46249371

Search of human proteins with 46249371

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|46249371 preferentially expressed antigen in melanoma [Homo
sapiens]
         (509 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|46249373 preferentially expressed antigen in melanoma [Homo s...  1020   0.0  
gi|46249371 preferentially expressed antigen in melanoma [Homo s...  1020   0.0  
gi|46249369 preferentially expressed antigen in melanoma [Homo s...  1020   0.0  
gi|46249367 preferentially expressed antigen in melanoma [Homo s...  1020   0.0  
gi|5174641 preferentially expressed antigen in melanoma [Homo sa...  1020   0.0  
gi|124249372 PRAME family member 12 [Homo sapiens]                    468   e-132
gi|239741053 PREDICTED: similar to Putative PRAME family member ...   454   e-128
gi|59676587 PRAME family member 8 [Homo sapiens]                      452   e-127
gi|59676593 PRAME family member 7 [Homo sapiens]                      451   e-127
gi|148356236 PRAME family member 15 [Homo sapiens]                    447   e-125
gi|61102721 PRAME family member 9 [Homo sapiens]                      447   e-125
gi|61696142 PRAME family member 5 [Homo sapiens]                      444   e-125
gi|59958373 PRAME family member 4 [Homo sapiens]                      444   e-124
gi|58219004 PRAME family member 6 [Homo sapiens]                      444   e-124
gi|239741045 PREDICTED: PRAME family member 23 [Homo sapiens]         441   e-124
gi|153792112 PRAME family member 20 [Homo sapiens]                    437   e-122
gi|153945800 PRAME family member 21 [Homo sapiens]                    437   e-122
gi|239741043 PREDICTED: PRAME family member 11 [Homo sapiens]         436   e-122
gi|239741047 PREDICTED: PRAME family member 25-like [Homo sapiens]    398   e-111
gi|226437621 PRAME family member 11 [Homo sapiens]                    386   e-107
gi|194018546 PRAME family member 10 [Homo sapiens]                    361   e-99 
gi|154800493 PRAME family member 22 [Homo sapiens]                    360   2e-99
gi|66954681 PRAME family member 13 [Homo sapiens]                     358   6e-99
gi|157426839 PRAME family member 17 [Homo sapiens]                    353   3e-97
gi|153791443 PRAME family member 18 [Homo sapiens]                    353   3e-97
gi|12738831 PRAME family member 1 [Homo sapiens]                      352   4e-97
gi|194306638 PRAME family member 3 [Homo sapiens]                     352   5e-97
gi|113865933 PRAME family member 16 [Homo sapiens]                    352   5e-97
gi|194306635 PRAME family member 19 [Homo sapiens]                    349   3e-96
gi|12738834 PRAME family member 2 [Homo sapiens]                      341   8e-94

>gi|46249373 preferentially expressed antigen in melanoma [Homo
           sapiens]
          Length = 509

 Score = 1020 bits (2637), Expect = 0.0
 Identities = 509/509 (100%), Positives = 509/509 (100%)

Query: 1   MERRRLWGSIQSRYISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAA 60
           MERRRLWGSIQSRYISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAA
Sbjct: 1   MERRRLWGSIQSRYISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAA 60

Query: 61  FDGRHSQTLKAMVQAWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQ 120
           FDGRHSQTLKAMVQAWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQ
Sbjct: 61  FDGRHSQTLKAMVQAWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQ 120

Query: 121 VLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVD 180
           VLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVD
Sbjct: 121 VLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVD 180

Query: 181 LFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEV 240
           LFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEV
Sbjct: 181 LFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEV 240

Query: 241 TCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQA 300
           TCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQA
Sbjct: 241 TCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQA 300

Query: 301 LYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVM 360
           LYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVM
Sbjct: 301 LYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVM 360

Query: 361 LTDVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISI 420
           LTDVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISI
Sbjct: 361 LTDVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISI 420

Query: 421 SALQSLLQHLIGLSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMV 480
           SALQSLLQHLIGLSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMV
Sbjct: 421 SALQSLLQHLIGLSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMV 480

Query: 481 WLSANPCPHCGDRTFYDPEPILCPCFMPN 509
           WLSANPCPHCGDRTFYDPEPILCPCFMPN
Sbjct: 481 WLSANPCPHCGDRTFYDPEPILCPCFMPN 509


>gi|46249371 preferentially expressed antigen in melanoma [Homo
           sapiens]
          Length = 509

 Score = 1020 bits (2637), Expect = 0.0
 Identities = 509/509 (100%), Positives = 509/509 (100%)

Query: 1   MERRRLWGSIQSRYISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAA 60
           MERRRLWGSIQSRYISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAA
Sbjct: 1   MERRRLWGSIQSRYISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAA 60

Query: 61  FDGRHSQTLKAMVQAWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQ 120
           FDGRHSQTLKAMVQAWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQ
Sbjct: 61  FDGRHSQTLKAMVQAWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQ 120

Query: 121 VLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVD 180
           VLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVD
Sbjct: 121 VLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVD 180

Query: 181 LFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEV 240
           LFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEV
Sbjct: 181 LFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEV 240

Query: 241 TCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQA 300
           TCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQA
Sbjct: 241 TCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQA 300

Query: 301 LYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVM 360
           LYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVM
Sbjct: 301 LYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVM 360

Query: 361 LTDVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISI 420
           LTDVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISI
Sbjct: 361 LTDVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISI 420

Query: 421 SALQSLLQHLIGLSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMV 480
           SALQSLLQHLIGLSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMV
Sbjct: 421 SALQSLLQHLIGLSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMV 480

Query: 481 WLSANPCPHCGDRTFYDPEPILCPCFMPN 509
           WLSANPCPHCGDRTFYDPEPILCPCFMPN
Sbjct: 481 WLSANPCPHCGDRTFYDPEPILCPCFMPN 509


>gi|46249369 preferentially expressed antigen in melanoma [Homo
           sapiens]
          Length = 509

 Score = 1020 bits (2637), Expect = 0.0
 Identities = 509/509 (100%), Positives = 509/509 (100%)

Query: 1   MERRRLWGSIQSRYISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAA 60
           MERRRLWGSIQSRYISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAA
Sbjct: 1   MERRRLWGSIQSRYISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAA 60

Query: 61  FDGRHSQTLKAMVQAWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQ 120
           FDGRHSQTLKAMVQAWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQ
Sbjct: 61  FDGRHSQTLKAMVQAWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQ 120

Query: 121 VLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVD 180
           VLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVD
Sbjct: 121 VLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVD 180

Query: 181 LFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEV 240
           LFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEV
Sbjct: 181 LFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEV 240

Query: 241 TCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQA 300
           TCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQA
Sbjct: 241 TCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQA 300

Query: 301 LYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVM 360
           LYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVM
Sbjct: 301 LYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVM 360

Query: 361 LTDVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISI 420
           LTDVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISI
Sbjct: 361 LTDVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISI 420

Query: 421 SALQSLLQHLIGLSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMV 480
           SALQSLLQHLIGLSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMV
Sbjct: 421 SALQSLLQHLIGLSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMV 480

Query: 481 WLSANPCPHCGDRTFYDPEPILCPCFMPN 509
           WLSANPCPHCGDRTFYDPEPILCPCFMPN
Sbjct: 481 WLSANPCPHCGDRTFYDPEPILCPCFMPN 509


>gi|46249367 preferentially expressed antigen in melanoma [Homo
           sapiens]
          Length = 509

 Score = 1020 bits (2637), Expect = 0.0
 Identities = 509/509 (100%), Positives = 509/509 (100%)

Query: 1   MERRRLWGSIQSRYISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAA 60
           MERRRLWGSIQSRYISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAA
Sbjct: 1   MERRRLWGSIQSRYISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAA 60

Query: 61  FDGRHSQTLKAMVQAWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQ 120
           FDGRHSQTLKAMVQAWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQ
Sbjct: 61  FDGRHSQTLKAMVQAWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQ 120

Query: 121 VLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVD 180
           VLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVD
Sbjct: 121 VLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVD 180

Query: 181 LFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEV 240
           LFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEV
Sbjct: 181 LFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEV 240

Query: 241 TCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQA 300
           TCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQA
Sbjct: 241 TCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQA 300

Query: 301 LYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVM 360
           LYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVM
Sbjct: 301 LYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVM 360

Query: 361 LTDVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISI 420
           LTDVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISI
Sbjct: 361 LTDVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISI 420

Query: 421 SALQSLLQHLIGLSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMV 480
           SALQSLLQHLIGLSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMV
Sbjct: 421 SALQSLLQHLIGLSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMV 480

Query: 481 WLSANPCPHCGDRTFYDPEPILCPCFMPN 509
           WLSANPCPHCGDRTFYDPEPILCPCFMPN
Sbjct: 481 WLSANPCPHCGDRTFYDPEPILCPCFMPN 509


>gi|5174641 preferentially expressed antigen in melanoma [Homo
           sapiens]
          Length = 509

 Score = 1020 bits (2637), Expect = 0.0
 Identities = 509/509 (100%), Positives = 509/509 (100%)

Query: 1   MERRRLWGSIQSRYISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAA 60
           MERRRLWGSIQSRYISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAA
Sbjct: 1   MERRRLWGSIQSRYISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAA 60

Query: 61  FDGRHSQTLKAMVQAWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQ 120
           FDGRHSQTLKAMVQAWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQ
Sbjct: 61  FDGRHSQTLKAMVQAWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQ 120

Query: 121 VLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVD 180
           VLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVD
Sbjct: 121 VLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVD 180

Query: 181 LFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEV 240
           LFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEV
Sbjct: 181 LFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEV 240

Query: 241 TCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQA 300
           TCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQA
Sbjct: 241 TCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQA 300

Query: 301 LYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVM 360
           LYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVM
Sbjct: 301 LYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVM 360

Query: 361 LTDVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISI 420
           LTDVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISI
Sbjct: 361 LTDVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISI 420

Query: 421 SALQSLLQHLIGLSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMV 480
           SALQSLLQHLIGLSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMV
Sbjct: 421 SALQSLLQHLIGLSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMV 480

Query: 481 WLSANPCPHCGDRTFYDPEPILCPCFMPN 509
           WLSANPCPHCGDRTFYDPEPILCPCFMPN
Sbjct: 481 WLSANPCPHCGDRTFYDPEPILCPCFMPN 509


>gi|124249372 PRAME family member 12 [Homo sapiens]
          Length = 483

 Score =  468 bits (1204), Expect = e-132
 Identities = 255/482 (52%), Positives = 327/482 (67%), Gaps = 14/482 (2%)

Query: 22  SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81
           +P RL+ELA QSLL+D ALAI  LE LPRELFPPLFM AF  R  +TL  MVQAWPFTCL
Sbjct: 5   APPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWPFTCL 64

Query: 82  PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141
           PLG LMK    +LE F+AVL+GLD LLAQ+VRPRRWKLQVLDLR N  ++FW +WSG  A
Sbjct: 65  PLGSLMKS--CNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLR-NVDENFWGIWSGASA 121

Query: 142 SLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKR 201
                  PEA   ++K+R          Q   P+ V++DL  K G  DE  ++ +E  K+
Sbjct: 122 L-----SPEA---LSKRRTAGNCPRPGGQQ--PLMVILDLCFKNGMLDECLTHFLEWGKQ 171

Query: 202 KKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMIN 261
           +K +L +CCK+L+IF + +  I  +L  V+LD I+++EV C W+L  L +F+PYLGQM N
Sbjct: 172 RKGLLHVCCKELQIFGIAIHRIIEVLNTVELDCIQEVEVCCPWELSILIRFAPYLGQMRN 231

Query: 262 LRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHVM 321
           LR+L+L +IH S+ I  +++EQ++ QFTSQFL L   Q LY+ S+ FL G LDQLLR + 
Sbjct: 232 LRKLVLFNIHVSACIPLDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCLQ 291

Query: 322 NPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATLQ 381
            PLET+ +T C LSE D+ HLS  PS+ QL  L L G+ LT  SPEPL  LLE+A ATLQ
Sbjct: 292 APLETVVMTECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATLQ 351

Query: 382 DLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVLY 441
            L  ++CGI D QL A+LP+LS CSQL+T SF GN IS++AL++LL+H +GLS L+  LY
Sbjct: 352 TLDLEDCGIVDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELY 411

Query: 442 PVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFYDPEPI 501
           P PLESY D  G L   R + L A L + L +L +P ++  S  PCP CG R  YD EP 
Sbjct: 412 PAPLESY-DAQGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCGIRASYDLEPS 470

Query: 502 LC 503
            C
Sbjct: 471 HC 472


>gi|239741053 PREDICTED: similar to Putative PRAME family member 24
           [Homo sapiens]
          Length = 474

 Score =  454 bits (1168), Expect = e-128
 Identities = 255/485 (52%), Positives = 329/485 (67%), Gaps = 16/485 (3%)

Query: 22  SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81
           +P RL+ELA Q LL+D+ALAI+ +E LPRELFP LFM AF  R  +TLK MVQAWPFT L
Sbjct: 5   APPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWPFTRL 64

Query: 82  PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141
           PLG LMK  HL  E+ K+VL+G+DVLL QEVRPR+ KLQVLDLR N  ++F  ++SG  A
Sbjct: 65  PLGSLMKSPHL--ESLKSVLEGVDVLLTQEVRPRQSKLQVLDLR-NVDENFCDIFSGATA 121

Query: 142 SLYSFPEPEAAQPMTKKRKVDGL-STEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVK 200
           S   FPE      +++K+  D    T  +QPF+   V +DL LK    DE  ++L+E  K
Sbjct: 122 S---FPEA-----LSQKQTADNCPGTGRQQPFM---VFIDLCLKNRTLDECLTHLLEWGK 170

Query: 201 RKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMI 260
           ++K +L +CCK+L++F MP+  I  +L MV+LD I+++EV C W+L TL KF+PYLGQM 
Sbjct: 171 QRKGLLHVCCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMR 230

Query: 261 NLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHV 320
           NLR+L+L +I AS+ I P+ + Q+IA+FTSQFL L   Q L + S+ FL G LDQLLR +
Sbjct: 231 NLRKLVLFNIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCL 290

Query: 321 MNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATL 380
              LE + +T+C LSE D+ HLS  PS+ QL  L L GV LT  SPEPL  LLE+  ATL
Sbjct: 291 QASLEMVVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATL 350

Query: 381 QDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVL 440
           Q L  ++CGI D QL A+LP LS CSQL+T SF GN IS++AL++LL+H +GLS L+  L
Sbjct: 351 QTLDLEDCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLEL 410

Query: 441 YPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFYDPEP 500
           YP PLESY D  G L   R A L A L + L +L +P ++     PCP CG R  YD EP
Sbjct: 411 YPAPLESY-DTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEP 469

Query: 501 ILCPC 505
             C C
Sbjct: 470 SHCLC 474


>gi|59676587 PRAME family member 8 [Homo sapiens]
          Length = 474

 Score =  452 bits (1164), Expect = e-127
 Identities = 254/485 (52%), Positives = 329/485 (67%), Gaps = 16/485 (3%)

Query: 22  SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81
           +P RL+ELA Q LL+D+ALAI+ +E LPRELFP LFM AF  R  +TLK MVQAWPFT L
Sbjct: 5   APPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWPFTRL 64

Query: 82  PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141
           PLG LMK  HL  E+ K+VL+G+DVLL QEVRPR+ KLQVLDLR N  ++F  ++SG  A
Sbjct: 65  PLGSLMKSPHL--ESLKSVLEGVDVLLTQEVRPRQSKLQVLDLR-NVDENFCDIFSGATA 121

Query: 142 SLYSFPEPEAAQPMTKKRKVDGL-STEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVK 200
           S   FPE      +++K+  D    T  +QPF+   V +DL LK    DE  ++L+E  K
Sbjct: 122 S---FPEA-----LSQKQTADNCPGTGRQQPFM---VFIDLCLKNRTLDECLTHLLEWGK 170

Query: 201 RKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMI 260
           ++K +L +CC++L++F MP+  I  +L MV+LD I+++EV C W+L TL KF+PYLGQM 
Sbjct: 171 QRKGLLHVCCQELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMR 230

Query: 261 NLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHV 320
           NLR+L+L +I AS+ I P+ + Q+IA+FTSQFL L   Q L + S+ FL G LDQLLR +
Sbjct: 231 NLRKLVLFNIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCL 290

Query: 321 MNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATL 380
              LE + +T+C LSE D+ HLS  PS+ QL  L L GV LT  SPEPL  LLE+  ATL
Sbjct: 291 QASLEMVVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATL 350

Query: 381 QDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVL 440
           Q L  ++CGI D QL A+LP LS CSQL+T SF GN IS++AL++LL+H +GLS L+  L
Sbjct: 351 QTLDLEDCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLEL 410

Query: 441 YPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFYDPEP 500
           YP PLESY D  G L   R A L A L + L +L +P ++     PCP CG R  YD EP
Sbjct: 411 YPAPLESY-DTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEP 469

Query: 501 ILCPC 505
             C C
Sbjct: 470 SHCLC 474


>gi|59676593 PRAME family member 7 [Homo sapiens]
          Length = 474

 Score =  451 bits (1161), Expect = e-127
 Identities = 254/485 (52%), Positives = 328/485 (67%), Gaps = 16/485 (3%)

Query: 22  SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81
           +P RL+ELA Q LL+D+ALAI+ +E LPRELFP LFM AF  R  +TLK MVQAWPFT L
Sbjct: 5   APPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWPFTRL 64

Query: 82  PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141
           PLG LMK  HL  E+ K+VL+G+DVLL QEVRPR+ KLQVLDLR N  ++F  ++SG  A
Sbjct: 65  PLGSLMKSPHL--ESLKSVLEGVDVLLTQEVRPRQSKLQVLDLR-NVDENFCDIFSGATA 121

Query: 142 SLYSFPEPEAAQPMTKKRKVDGL-STEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVK 200
           S   FPE      +++K+  D    T  +QPF+   V +DL LK    DE  ++L+E  K
Sbjct: 122 S---FPEA-----LSQKQTADNCPGTGRQQPFM---VFIDLCLKNRTLDECLTHLLEWGK 170

Query: 201 RKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMI 260
           ++K +L +CCK+L++F MP+  I  +L MV+LD I+++EV C W+L TL KF+PYLGQM 
Sbjct: 171 QRKGLLHVCCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMR 230

Query: 261 NLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHV 320
           NLR+L+L +I AS+ I P+ + Q+IA+FTSQFL L   Q L + S+ FL G LDQLLR +
Sbjct: 231 NLRKLVLFNIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCL 290

Query: 321 MNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATL 380
              LE + +T+C LSE D+ HLS  PS+ QL  L L GV LT  SPEPL  LLE+  ATL
Sbjct: 291 QASLEMVVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATL 350

Query: 381 QDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVL 440
           Q L  ++CGI D QL A+LP LS CSQL+T SF GN IS++AL++LL+H +GLS L+  L
Sbjct: 351 QTLDLEDCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLEL 410

Query: 441 YPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFYDPEP 500
           YP PLESY D  G L   R A L A L +   +L +P ++     PCP CG R  YD EP
Sbjct: 411 YPAPLESY-DTQGALCWGRFAELGAELMKTPRDLRQPKIIVFCTVPCPRCGIRASYDLEP 469

Query: 501 ILCPC 505
             C C
Sbjct: 470 SHCLC 474


>gi|148356236 PRAME family member 15 [Homo sapiens]
          Length = 478

 Score =  447 bits (1149), Expect = e-125
 Identities = 245/485 (50%), Positives = 322/485 (66%), Gaps = 13/485 (2%)

Query: 15  ISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQ 74
           + MS+ T PR L+ELAG+SLL+D+ALA++ LE LP ELFPPLFM AF  R  + LK MVQ
Sbjct: 1   MKMSIRTPPR-LLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQ 59

Query: 75  AWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWT 134
           AWPF  LPL  L+K   L  E F+AVLDGLD LL Q VRPRRWKLQVLDL+ +  ++FW 
Sbjct: 60  AWPFRRLPLRPLIKMPCL--EAFQAVLDGLDALLTQGVRPRRWKLQVLDLQ-DVCENFWM 116

Query: 135 VWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSY 194
           VWS   A           +P+    ++ G          P+ V V+L+LK    DE  +Y
Sbjct: 117 VWSEAMAHGCFLNAKRNKKPVQDCPRMRGRQ--------PLTVFVELWLKNRTLDEYLTY 168

Query: 195 LIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSP 254
           L+  VK++K++L LCCKKLKI  MP ++I+ ILKMV LD I+++EV C W LP L +F+P
Sbjct: 169 LLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTP 228

Query: 255 YLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLD 314
           YLG M NL++L+LSH+  S Y+SPE++++ + QFT+QFL L+CLQ LY++S+ FL G LD
Sbjct: 229 YLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLD 288

Query: 315 QLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLE 374
           QLL  +   L+ L+ITNC L E D+ HLSQ PS+SQL  L LSG+ LT+ S  PLQ LLE
Sbjct: 289 QLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLE 348

Query: 375 RASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLS 434
           + +ATL+ L  D+CGI D Q+ A+LP+LS C +L T SF GN I ++ L++LL H I L 
Sbjct: 349 KVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILK 408

Query: 435 NLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRT 494
           NL   LYP P ESY    GTL   R A + A L   + +L  P  +    + CP CG+R+
Sbjct: 409 NLCVELYPAPRESY-GADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRS 467

Query: 495 FYDPE 499
           FYD E
Sbjct: 468 FYDLE 472


>gi|61102721 PRAME family member 9 [Homo sapiens]
          Length = 478

 Score =  447 bits (1149), Expect = e-125
 Identities = 245/485 (50%), Positives = 322/485 (66%), Gaps = 13/485 (2%)

Query: 15  ISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQ 74
           + MS+ T PR L+ELAG+SLL+D+ALA++ LE LP ELFPPLFM AF  R  + LK MVQ
Sbjct: 1   MKMSIRTPPR-LLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQ 59

Query: 75  AWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWT 134
           AWPF  LPL  L+K   L  E F+AVLDGLD LL Q VRPRRWKLQVLDL+ +  ++FW 
Sbjct: 60  AWPFRRLPLRPLIKMPCL--EAFQAVLDGLDALLTQGVRPRRWKLQVLDLQ-DVCENFWM 116

Query: 135 VWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSY 194
           VWS   A           +P+    ++ G          P+ V V+L+LK    DE  +Y
Sbjct: 117 VWSEAMAHGCFLNAKRNKKPVQDCPRMRGRQ--------PLTVFVELWLKNRTLDEYLTY 168

Query: 195 LIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSP 254
           L+  VK++K++L LCCKKLKI  MP ++I+ ILKMV LD I+++EV C W LP L +F+P
Sbjct: 169 LLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTP 228

Query: 255 YLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLD 314
           YLG M NL++L+LSH+  S Y+SPE++++ + QFT+QFL L+CLQ LY++S+ FL G LD
Sbjct: 229 YLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLD 288

Query: 315 QLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLE 374
           QLL  +   L+ L+ITNC L E D+ HLSQ PS+SQL  L LSG+ LT+ S  PLQ LLE
Sbjct: 289 QLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLE 348

Query: 375 RASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLS 434
           + +ATL+ L  D+CGI D Q+ A+LP+LS C +L T SF GN I ++ L++LL H I L 
Sbjct: 349 KVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILK 408

Query: 435 NLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRT 494
           NL   LYP P ESY    GTL   R A + A L   + +L  P  +    + CP CG+R+
Sbjct: 409 NLCVELYPAPRESY-GADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRS 467

Query: 495 FYDPE 499
           FYD E
Sbjct: 468 FYDLE 472


>gi|61696142 PRAME family member 5 [Homo sapiens]
          Length = 476

 Score =  444 bits (1143), Expect = e-125
 Identities = 246/489 (50%), Positives = 322/489 (65%), Gaps = 13/489 (2%)

Query: 17  MSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAW 76
           MS+ T PR L+ELAG+SLL+D+ALA++ LE LP ELFPPLFM AF  R  + LK MVQAW
Sbjct: 1   MSIRTPPR-LLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAW 59

Query: 77  PFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVW 136
           PF  LPL  L+K   L  E F+AVLDGLD LL Q V PRRWKLQVLDL+ +  ++FW VW
Sbjct: 60  PFRRLPLRPLIKMPCL--EAFQAVLDGLDALLTQGVHPRRWKLQVLDLQ-DVCENFWMVW 116

Query: 137 SGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLI 196
           S   A           +P+    ++ G          P+ V V+L+LK    DE  + L+
Sbjct: 117 SEAMAHGCFLNAKRNKKPVQDCPRMRGQQ--------PLTVFVELWLKNRTLDEYLTCLL 168

Query: 197 EKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYL 256
             VK++K++L LCCKKLKI  MP ++I+ ILKMV LD I+++EV C W LP L +F+PYL
Sbjct: 169 LWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYL 228

Query: 257 GQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQL 316
           G M NL++L+LSH+  S Y+SPE++++ + QFT+QFL L CLQ L ++S+ FL G LDQL
Sbjct: 229 GHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQL 288

Query: 317 LRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERA 376
           L  +   L+ L+ITNC L E D+ HLSQ PS+SQL  L LSG+ LT+ S  PLQ LLE+ 
Sbjct: 289 LSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKV 348

Query: 377 SATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNL 436
           +ATL+ L  D+CGI D Q+ A+LP+LS C +L T SF GN IS++ L++LL H I L NL
Sbjct: 349 AATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNL 408

Query: 437 THVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFY 496
              LYP P ESY D  GTL   R A + A L + + +L  P  +    + CP CG+R+FY
Sbjct: 409 CVELYPAPRESY-DADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFY 467

Query: 497 DPEPILCPC 505
           D E   C C
Sbjct: 468 DLEADQCCC 476


>gi|59958373 PRAME family member 4 [Homo sapiens]
          Length = 478

 Score =  444 bits (1141), Expect = e-124
 Identities = 243/485 (50%), Positives = 321/485 (66%), Gaps = 13/485 (2%)

Query: 15  ISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQ 74
           + MS+WT PR L+ELAG+SLL+D+ALA++ LE LP ELFPPLFM AF  R  + LK MVQ
Sbjct: 1   MKMSIWTPPR-LLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQ 59

Query: 75  AWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWT 134
           +WPF  LPL  L+K   L  E F+AVLDGLD LL   VRPRRWKLQVLDL+ +  ++FW 
Sbjct: 60  SWPFRRLPLRPLIKMPCL--EAFQAVLDGLDALLNLGVRPRRWKLQVLDLQ-DVCENFWM 116

Query: 135 VWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSY 194
           VWS   A           +P+    ++ G          P+ V V+L+LK    DE  + 
Sbjct: 117 VWSEAMAHGCFLNAKRNKKPVEDCPRMRGRQ--------PLTVFVELWLKNRTLDEYLTC 168

Query: 195 LIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSP 254
           L+  VK++K++L LCCKKLKI  MP ++I+ ILKMV LD I+++EV C W LP L +F+P
Sbjct: 169 LLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTP 228

Query: 255 YLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLD 314
           YLG M NL++L+LSH+  S Y+SPE++++ + QFT+QFL L+CLQ LY++S+ FL G LD
Sbjct: 229 YLGHMRNLQKLILSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLD 288

Query: 315 QLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLE 374
           QLL  +   L+ L+ITNC L E D+ HLSQ PS+SQL  L LSG+ LT+ S  PLQ LLE
Sbjct: 289 QLLSCLKTSLKFLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLE 348

Query: 375 RASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLS 434
           + +ATL+ L  D+CGI D Q+ A+LP+LS C +L T SF GN I ++ L++LL H I L 
Sbjct: 349 KVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILK 408

Query: 435 NLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRT 494
           NL   LYP P ESY    GTL   R A + A L   + +L  P  +    + CP CG+R+
Sbjct: 409 NLCVELYPAPRESY-GADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRS 467

Query: 495 FYDPE 499
           FYD E
Sbjct: 468 FYDLE 472


>gi|58219004 PRAME family member 6 [Homo sapiens]
          Length = 476

 Score =  444 bits (1141), Expect = e-124
 Identities = 246/489 (50%), Positives = 321/489 (65%), Gaps = 13/489 (2%)

Query: 17  MSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAW 76
           MS+ T PR L+ELAG+SLL+D+ALA++ LE LP ELFPPLFM AF  R  + LK MVQAW
Sbjct: 1   MSIRTPPR-LLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAW 59

Query: 77  PFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVW 136
           PF  LPL  L+K   L  E F+AVLDGLD LL Q V PRRWKLQVLDL+ +  ++FW VW
Sbjct: 60  PFRRLPLRPLIKMPCL--EAFQAVLDGLDALLTQGVHPRRWKLQVLDLQ-DVCENFWMVW 116

Query: 137 SGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLI 196
           S   A            P+    ++ G          P+ V V+L+LK    DE  + L+
Sbjct: 117 SEAMARGCFLNAKRNKTPVQDCPRMRGQQ--------PLTVFVELWLKNRTLDEYLTCLL 168

Query: 197 EKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYL 256
             VK++K++L LCCKKLKI  MP ++I+ ILKMV LD I+++EV C W LP L +F+PYL
Sbjct: 169 LWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYL 228

Query: 257 GQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQL 316
           G M NL++L+LSH+  S Y+SPE++++ + QFT+QFL L CLQ L ++S+ FL G LDQL
Sbjct: 229 GHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQL 288

Query: 317 LRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERA 376
           L  +   L+ L+ITNC L E D+ HLSQ PS+SQL  L LSG+ LT+ S  PLQ LLE+ 
Sbjct: 289 LSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKV 348

Query: 377 SATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNL 436
           +ATL+ L  D+CGI D Q+ A+LP+LS C +L T SF GN IS++ L++LL H I L NL
Sbjct: 349 AATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNL 408

Query: 437 THVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFY 496
              LYP P ESY D  GTL   R A + A L + + +L  P  +    + CP CG+R+FY
Sbjct: 409 CVELYPAPRESY-DADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFY 467

Query: 497 DPEPILCPC 505
           D E   C C
Sbjct: 468 DLEADQCCC 476


>gi|239741045 PREDICTED: PRAME family member 23 [Homo sapiens]
          Length = 476

 Score =  441 bits (1135), Expect = e-124
 Identities = 245/489 (50%), Positives = 321/489 (65%), Gaps = 13/489 (2%)

Query: 17  MSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAW 76
           MS+ T PR L+ELAG+SLL+D+ALA++ LE LP ELFPPLFM AF  R  + LK MVQAW
Sbjct: 1   MSIRTPPR-LLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAW 59

Query: 77  PFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVW 136
           PF  LPL  L+K   L  E F+AVLDGLD LL Q V PRRWKLQVLDL+ +  ++FW VW
Sbjct: 60  PFRRLPLRPLIKMPCL--EAFQAVLDGLDALLTQGVHPRRWKLQVLDLQ-DVCENFWMVW 116

Query: 137 SGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLI 196
           S   A           +P+    ++ G          P+ V V+L+LK    DE  + L+
Sbjct: 117 SEAMAHGCFLNAKRNKKPVQDCPRMRGQQ--------PLTVFVELWLKNRTLDEYLTCLL 168

Query: 197 EKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYL 256
             VK++K++L LCCKKLKI  MP ++I+ ILKMV LD I+++EV C W LP L +F+PYL
Sbjct: 169 LWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYL 228

Query: 257 GQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQL 316
           G M NL++L+LSH+  S Y+SPE++++ + QFT+QFL L CLQ L ++S+ FL G LDQL
Sbjct: 229 GHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQL 288

Query: 317 LRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERA 376
           L  +   L+ L+ITNC L E D+ HLSQ PS+SQL  L LSG+ LT+ S  PLQ LLE+ 
Sbjct: 289 LSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKV 348

Query: 377 SATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNL 436
           +ATL+ L  D+CGI D Q+ A+LP+LS C +L T SF GN IS++ L++LL H I L NL
Sbjct: 349 AATLEYLDLDDCGIIDSQVNAILPALSCCFELNTFSFCGNPISMATLENLLSHTIILKNL 408

Query: 437 THVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFY 496
              LYP P ESY D  GTL   R   + A L + + +L  P  +    + CP CG+R+FY
Sbjct: 409 CVELYPAPRESY-DADGTLCWSRFPQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFY 467

Query: 497 DPEPILCPC 505
           D E   C C
Sbjct: 468 DLEADQCCC 476


>gi|153792112 PRAME family member 20 [Homo sapiens]
          Length = 475

 Score =  437 bits (1124), Expect = e-122
 Identities = 251/489 (51%), Positives = 318/489 (65%), Gaps = 14/489 (2%)

Query: 17  MSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAW 76
           MS+ T PR L+ELAG+SLL+DEALAI+ LE LP ELFPPLFM AF  RH + LK MVQAW
Sbjct: 1   MSIRTPPR-LLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAW 59

Query: 77  PFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVW 136
           PF  LPLG LMK      ETF+AVLDGLD LL   VR RRWKLQVLDL+  S ++FW VW
Sbjct: 60  PFLRLPLGSLMKRPCP--ETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVS-ENFWMVW 116

Query: 137 SGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLI 196
           S   A       P A   M +K   D      +QP   + V +DL LK    DE F+ L 
Sbjct: 117 SEAMARRCL---PNAM--MNRKPVQDCPRMRGQQP---LTVFIDLCLKNRTLDEYFTCLF 168

Query: 197 EKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYL 256
             VK+++ ++ LCCKKLK+  M   +I+ ILK V LD I+++EV C W LP LA+F+PYL
Sbjct: 169 LWVKQREGLVHLCCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYL 228

Query: 257 GQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQL 316
           GQM NLR+L+LS I  S YISPE++++++ QFT+QFL L+CLQ LY++S+ FL G LDQ+
Sbjct: 229 GQMRNLRKLVLSDID-SRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQM 287

Query: 317 LRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERA 376
           L  +   L  L+ITNC L E D+ HLS+ PS+ QL  L LSG  L + S  PLQ LLE+ 
Sbjct: 288 LSCLKTSLNILAITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKV 347

Query: 377 SATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNL 436
           +ATL+ L  D+CGI D Q+ A+LP+LS C +LTT SF GN IS + L++LL H I L+NL
Sbjct: 348 AATLEYLDLDDCGIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNL 407

Query: 437 THVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFY 496
              LYP P ESY D+ G +   R A L A L   +  L  P  +    + CP CG+R+ Y
Sbjct: 408 CLELYPAPRESY-DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLY 466

Query: 497 DPEPILCPC 505
           D E   C C
Sbjct: 467 DLEVDRCCC 475


>gi|153945800 PRAME family member 21 [Homo sapiens]
          Length = 475

 Score =  437 bits (1124), Expect = e-122
 Identities = 251/489 (51%), Positives = 318/489 (65%), Gaps = 14/489 (2%)

Query: 17  MSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAW 76
           MS+ T PR L+ELAG+SLL+DEALAI+ LE LP ELFPPLFM AF  RH + LK MVQAW
Sbjct: 1   MSIRTPPR-LLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAW 59

Query: 77  PFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVW 136
           PF  LPLG LMK      ETF+AVLDGLD LL   VR RRWKLQVLDL+  S ++FW VW
Sbjct: 60  PFLRLPLGSLMKRPCP--ETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVS-ENFWMVW 116

Query: 137 SGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLI 196
           S   A       P A   M +K   D      +QP   + V +DL LK    DE F+ L 
Sbjct: 117 SEAMARRCL---PNAM--MNRKPVQDCPRMRGQQP---LTVFIDLCLKNRTLDEYFTCLF 168

Query: 197 EKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYL 256
             VK+++ ++ LCCKKLK+  M   +I+ ILK V LD I+++EV C W LP LA+F+PYL
Sbjct: 169 LWVKQREGLVHLCCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYL 228

Query: 257 GQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQL 316
           GQM NLR+L+LS I  S YISPE++++++ QFT+QFL L+CLQ LY++S+ FL G LDQ+
Sbjct: 229 GQMRNLRKLVLSDID-SRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQM 287

Query: 317 LRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERA 376
           L  +   L  L+ITNC L E D+ HLS+ PS+ QL  L LSG  L + S  PLQ LLE+ 
Sbjct: 288 LSCLKTSLNILAITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKV 347

Query: 377 SATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNL 436
           +ATL+ L  D+CGI D Q+ A+LP+LS C +LTT SF GN IS + L++LL H I L+NL
Sbjct: 348 AATLEYLDLDDCGIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNL 407

Query: 437 THVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFY 496
              LYP P ESY D+ G +   R A L A L   +  L  P  +    + CP CG+R+ Y
Sbjct: 408 CLELYPAPRESY-DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLY 466

Query: 497 DPEPILCPC 505
           D E   C C
Sbjct: 467 DLEVDRCCC 475


>gi|239741043 PREDICTED: PRAME family member 11 [Homo sapiens]
          Length = 513

 Score =  436 bits (1121), Expect = e-122
 Identities = 241/487 (49%), Positives = 318/487 (65%), Gaps = 13/487 (2%)

Query: 13  RYISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAM 72
           R++ MS+   PR L+EL G+SLL+D+ALA++ LE LP ELFPPLFM AF  R  + LK M
Sbjct: 34  RFMKMSIRIPPR-LLELXGRSLLRDQALAVSTLEELPTELFPPLFMEAFSRRRCEALKLM 92

Query: 73  VQAWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDF 132
           VQAWPF  LPL  L+K   L  E F+AVLDGLD LL Q VRPRRWKLQVLDL+ +  ++F
Sbjct: 93  VQAWPFRRLPLRPLIKMPCL--EAFQAVLDGLDALLTQGVRPRRWKLQVLDLQ-DVCENF 149

Query: 133 WTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELF 192
           W VWS   A               K+ K         +   P+ V V+L+LK    DE  
Sbjct: 150 WMVWSEAMA--------HGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTLDEYL 201

Query: 193 SYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKF 252
           + L+  VK+++++L LCCKKLKI  MP ++I+ ILKMV LD I+++EV C W LP L +F
Sbjct: 202 TCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPILTQF 261

Query: 253 SPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGR 312
           +PYLG + NL++L+LSH+  S Y+SPE++++ + QFT+QFL L+CLQ LY++S+ FL G 
Sbjct: 262 TPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGH 321

Query: 313 LDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQAL 372
           LDQLL  +   L+ L+ITNC L E D+ HLSQ PS+SQL  L LSG+ LT+ S  PLQ L
Sbjct: 322 LDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQIL 381

Query: 373 LERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIG 432
           LE+ +ATL+ L  D+CGI D Q+ A+LP+LS C +L T SF GN I ++ L++LL H I 
Sbjct: 382 LEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTII 441

Query: 433 LSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGD 492
           L NL   LYP P ESY    GTL   R A + A L + +  L  P  +    + CP  GD
Sbjct: 442 LKNLCLELYPAPQESY-GADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPDHGD 500

Query: 493 RTFYDPE 499
           R+FYD E
Sbjct: 501 RSFYDLE 507


>gi|239741047 PREDICTED: PRAME family member 25-like [Homo sapiens]
          Length = 474

 Score =  398 bits (1023), Expect = e-111
 Identities = 230/478 (48%), Positives = 306/478 (64%), Gaps = 14/478 (2%)

Query: 22  SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81
           +PRRL+ELAGQSLL D+ALAI+ L+ LPRELFPPLF+ AF  R  + LK MVQAWPF CL
Sbjct: 5   APRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWPFPCL 64

Query: 82  PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141
           PLG LMK   L  E    V+DG+D LLAQ+VRPRR KLQVL+LR +  ++FWT+WSG R 
Sbjct: 65  PLGSLMKTPDL--EILHYVVDGIDCLLAQKVRPRRRKLQVLELR-DVDENFWTIWSGARP 121

Query: 142 SLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKR 201
              S   PEA   M+K++ V+      E+   P++V +D+ LKE   DE  S+    V+ 
Sbjct: 122 LSCS---PEA---MSKRQTVEDCPRTGEKQ--PLKVFMDVCLKEKFMDEDLSFFSGWVQH 173

Query: 202 KKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMIN 261
           ++  + LCC K+  ++M + + + IL+ V  DSI+ LE+        + +FSPYL QM N
Sbjct: 174 RRGSVHLCCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSPYLSQMRN 233

Query: 262 LRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHVM 321
           LR+L +S      Y+     ++ IA FT+QFL L CLQ LY++S+ FL G LDQLL  + 
Sbjct: 234 LRKLFISD--GCRYLLSSDSQEQIAPFTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLK 291

Query: 322 NPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATLQ 381
             L+ L+ITNC L E D+ HLSQ PS+SQL  L LSG+ LT+ S  PLQ LLE+ +ATL+
Sbjct: 292 TSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLE 351

Query: 382 DLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVLY 441
            L  D+CGI D Q+ A+LP+LS C +L T SF GN IS++ L++LL H I L NL   LY
Sbjct: 352 YLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELY 411

Query: 442 PVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFYDPE 499
           P P ESY    GTL   R   + A L + + +L  P  +    + CP CG+R+FYD E
Sbjct: 412 PAPRESY-GADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCPDCGNRSFYDLE 468


>gi|226437621 PRAME family member 11 [Homo sapiens]
          Length = 436

 Score =  386 bits (992), Expect = e-107
 Identities = 214/442 (48%), Positives = 282/442 (63%), Gaps = 12/442 (2%)

Query: 58  MAAFDGRHSQTLKAMVQAWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRW 117
           M AF  R  + LK MVQAWPF  LPL  L+K   L  E F+AVLDGLD LL Q VRPRRW
Sbjct: 1   MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCL--EAFQAVLDGLDALLTQGVRPRRW 58

Query: 118 KLQVLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEV 177
           KLQVLDL+ +  ++FW VWS   A               K+ K         +   P+ V
Sbjct: 59  KLQVLDLQ-DVCENFWMVWSEAMA--------HGCFLNAKRNKTPVQDCPRMRERQPLTV 109

Query: 178 LVDLFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIED 237
            V+L+LK    DE  + L+  VK+++++L LCCKKLKI  MP ++I+ ILKMV LD I++
Sbjct: 110 FVELWLKNRTLDEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQE 169

Query: 238 LEVTCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQC 297
           +EV C W LP L +F+PYLG + NL++L+LSH+  S Y+SPE++++ + QFT+QFL L+C
Sbjct: 170 VEVNCKWILPILTQFTPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRC 229

Query: 298 LQALYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLS 357
           LQ LY++S+ FL G LDQLL  +   L+ L+ITNC L E D+ HLSQ PS+SQL  L LS
Sbjct: 230 LQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLS 289

Query: 358 GVMLTDVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNS 417
           G+ LT+ S  PLQ LLE+ +ATL+ L  D+CGI D Q+ A+LP+LS C +L T SF GN 
Sbjct: 290 GIRLTNYSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNP 349

Query: 418 ISISALQSLLQHLIGLSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRP 477
           I ++ L++LL H I L NL   LYP P ESY    GTL   R A + A L + +  L  P
Sbjct: 350 ICMATLENLLSHTIILKNLCLELYPAPQESY-GADGTLCWSRFAQIRAELMKKVRHLRHP 408

Query: 478 SMVWLSANPCPHCGDRTFYDPE 499
             +    + CP  GDR+FYD E
Sbjct: 409 KRILFCTDNCPDHGDRSFYDLE 430


>gi|194018546 PRAME family member 10 [Homo sapiens]
          Length = 474

 Score =  361 bits (926), Expect = e-99
 Identities = 213/471 (45%), Positives = 291/471 (61%), Gaps = 15/471 (3%)

Query: 22  SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81
           +P RL+ELAGQSLL+++ L I  L+ LPRE+FP +FM AF  R  + LK MVQAWPF  L
Sbjct: 5   APSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWPFLSL 64

Query: 82  PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141
           PLG LMK   LHLET +AVL GLD L+AQ+VRPRRWKLQVLDLR +  ++FWT+WSG R 
Sbjct: 65  PLGSLMKT--LHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLR-DVDENFWTIWSGARV 121

Query: 142 SLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKR 201
              S   PEA   M+K++ V+      E    P++V +DL LKE   DE  SYL   +  
Sbjct: 122 LSCS---PEA---MSKRQTVEDCPRMGEHQ--PLKVFIDLCLKESTLDECLSYLFGWIHY 173

Query: 202 KKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMIN 261
           ++ ++ LCC K++ ++MP    + +L+ +  DSI++LEV     L    KF+PYL QM N
Sbjct: 174 RRGLVHLCCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSN 233

Query: 262 LRRLLLSHIHASS-YISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHV 320
           LR L L+  +    Y+S +     I    S FL L   Q LY+  +  ++  L+ LLR++
Sbjct: 234 LRELFLAFGYERELYVSVQWP--CIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYL 291

Query: 321 MNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATL 380
            NPL     ++  L++ D+  LSQ PS+SQL  L L  +++     EPL  LLE+ +ATL
Sbjct: 292 KNPLGAFIFSDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATL 351

Query: 381 QDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVL 440
           + LV  +C I D QL  LLP+LSHCSQLTT +F+GN  S++AL+ LL+H  GLS L   L
Sbjct: 352 KTLVLKDCRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLEL 411

Query: 441 YPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCG 491
           YP PLES  D  G ++ E L  + A L   L E+ +P  ++    PCP+CG
Sbjct: 412 YPAPLESL-DYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCG 461


>gi|154800493 PRAME family member 22 [Homo sapiens]
          Length = 481

 Score =  360 bits (923), Expect = 2e-99
 Identities = 216/470 (45%), Positives = 295/470 (62%), Gaps = 13/470 (2%)

Query: 22  SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81
           +PRRL+ELAGQSLL D+ALAI+ L+ LPRELFPPLF+ AF  R  + LK MVQAWPF CL
Sbjct: 7   APRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWPFPCL 66

Query: 82  PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141
           PLG LMK   L  E    V+DG+D LLAQ+VRPRRWKLQVL+LR +  ++FWT+WSG R 
Sbjct: 67  PLGSLMKTPDL--EILHYVVDGIDCLLAQKVRPRRWKLQVLELR-DVDENFWTIWSGARP 123

Query: 142 SLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKR 201
              S   PEA   M+K++ V+      E+   P++V +D+ LKE   DE  S+    V+ 
Sbjct: 124 LSCS---PEA---MSKRQTVEDCPRTGEKQ--PLKVFMDVCLKEKFMDEDLSFFSGWVQH 175

Query: 202 KKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMIN 261
           ++  + LCC K+  ++M + + + IL+ V  DSI+ LE+        + +FS YL QM N
Sbjct: 176 RRGSVHLCCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSRYLSQMRN 235

Query: 262 LRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHVM 321
           LR+L +S       +S + +EQ +A+F+S  L L+ LQ LYV  + F RG LDQL+R + 
Sbjct: 236 LRKLFISD-GCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLR 294

Query: 322 NPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATLQ 381
           +PLETL++T   L + D+  L + PS+SQL  L+LS   L  +  EPL+ALLE+ +ATLQ
Sbjct: 295 SPLETLALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQ 354

Query: 382 DLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVLY 441
            L   +CGI D +L  +LP+LS CS LTT  F+GN  S+  L+ LL+H   LSNL+   Y
Sbjct: 355 TLFLVDCGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETY 414

Query: 442 PVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCG 491
           P P ES +D  G +  E L  L A L  +L E+  P  ++     CP CG
Sbjct: 415 PAPRESLDD-RGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCG 463


>gi|66954681 PRAME family member 13 [Homo sapiens]
          Length = 474

 Score =  358 bits (919), Expect = 6e-99
 Identities = 217/482 (45%), Positives = 296/482 (61%), Gaps = 13/482 (2%)

Query: 22  SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81
           +P RL+ELAGQSLL+D+AL+I+A+E LPR L+ PLFM AF  RH QTL  MVQAWPFTCL
Sbjct: 5   APPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWPFTCL 64

Query: 82  PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141
           PLG LMK   LHLET KA+L+GL +LL Q+ RPRRWKLQVLDLR +  ++FW  W G  A
Sbjct: 65  PLGSLMKT--LHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLR-DVDENFWARWPGAWA 121

Query: 142 SLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKR 201
            L  FPE      M+K++  +      E    P++V +D+ LKE   DE   YL + V +
Sbjct: 122 -LSCFPET-----MSKRQTAEDCPRMGEHQ--PLKVFIDICLKEIPQDECLRYLFQWVYQ 173

Query: 202 KKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMIN 261
           ++ ++ LCC KL  +  P++ ++  LK++ L+SI+ LE+        + K   YL +M N
Sbjct: 174 RRGLVHLCCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKN 233

Query: 262 LRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHVM 321
           LR+L+ S  H  S    E E + + +F+S FL L+ LQ L +  + F  G L+QL+R + 
Sbjct: 234 LRKLVFSRCH-HSMSDNELEGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQ 292

Query: 322 NPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATLQ 381
           NPLE L +T   L E D+  LSQ PS+  L  L+LS V+L  +S EPL ALLE+ +A+L+
Sbjct: 293 NPLENLELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLE 352

Query: 382 DLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVLY 441
            L+ + C I   QL A+LP LSHCSQLTT  F  N +S+ AL+ LL+H  GLS L+   Y
Sbjct: 353 TLILEGCQIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETY 412

Query: 442 PVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFYDPEPI 501
           P P ES   +   +  E  A L A L   L E+ +P  +++   PCP CG     + E  
Sbjct: 413 PAPEESLNSL-VRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELH 471

Query: 502 LC 503
           LC
Sbjct: 472 LC 473


>gi|157426839 PRAME family member 17 [Homo sapiens]
          Length = 474

 Score =  353 bits (905), Expect = 3e-97
 Identities = 213/471 (45%), Positives = 286/471 (60%), Gaps = 15/471 (3%)

Query: 22  SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81
           SP RL+ELAGQSLL+++ L I  L+ LPRE+FP +FM A   RH + LK MVQAWPF  L
Sbjct: 5   SPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWPFLRL 64

Query: 82  PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141
           PLG LMK  HL  ET +AVL GLD LLAQ++RPRRWKLQVLDLR +   +FWT+WSG RA
Sbjct: 65  PLGSLMKTPHL--ETLQAVLKGLDTLLAQKLRPRRWKLQVLDLR-DVDGNFWTIWSGARA 121

Query: 142 SLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKR 201
              S   PEA   M+K++ V+      E    P++V +DL  KE   DE  SYL   +  
Sbjct: 122 LSCS---PEA---MSKRQTVEDYPRTGEHQ--PLKVFIDLCQKESTLDECLSYLCRWIHY 173

Query: 202 KKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMIN 261
           ++ ++ LCC K++ ++MP    + +LK V  DSI++LE+     L    KF+PYL QM N
Sbjct: 174 RRGLVHLCCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSN 233

Query: 262 LRRLLLSHIHASS-YISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHV 320
           LR+L L+  +    Y+S +  +Q++      FL L   Q LY+  +  ++  L+ LLR +
Sbjct: 234 LRKLFLAFGYDDELYVSGQ--QQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCL 291

Query: 321 MNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATL 380
            NPL T    +  L++ D+  LSQ PS+SQL  L L  +++   + EPL ALLE+ +ATL
Sbjct: 292 KNPLGTFIFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATL 351

Query: 381 QDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVL 440
           + L   +C I D QL  LLP+LS CSQLTT  F GN  S +AL+ LL H  GLS L   L
Sbjct: 352 EILTLKDCQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLEL 411

Query: 441 YPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCG 491
           YP PLE   D  G ++ E LA + A L   L E+ +P  ++    PCP CG
Sbjct: 412 YPAPLECL-DNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCG 461


>gi|153791443 PRAME family member 18 [Homo sapiens]
          Length = 479

 Score =  353 bits (905), Expect = 3e-97
 Identities = 215/471 (45%), Positives = 295/471 (62%), Gaps = 15/471 (3%)

Query: 22  SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81
           +PRRL+ELAGQSLL+D+ALAI+ L+ LPRELFP LF+ AF  R  + LK MVQAWPF CL
Sbjct: 5   APRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWPFPCL 64

Query: 82  PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141
           PLG LMK   L  E    V+DG+D LLAQ+VRPRRWKLQVL++R +  ++FWT+WSG R 
Sbjct: 65  PLGSLMKTPDL--EILHYVVDGIDCLLAQKVRPRRWKLQVLEMR-DVDENFWTIWSGARP 121

Query: 142 SLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKR 201
              S   PEA   M+K++ V+      E+   P++V +D+ LKE + DE  S+    V+ 
Sbjct: 122 LSCS---PEA---MSKRQTVEDCPRTGEKQ--PLKVFMDVCLKEKSVDEDLSFFSGWVQH 173

Query: 202 KKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMIN 261
           ++  + LCC K+  ++M + + + IL+ V  DSI+ LE+        +A+ S YL QM N
Sbjct: 174 RRRSVHLCCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKN 233

Query: 262 LRRLLLSHIHASSYI-SPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHV 320
           LR+L +S      Y+ S E + Q +A+F+S FL L+ LQ LY+  + F  G LDQL+R +
Sbjct: 234 LRKLFISD--GCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCL 291

Query: 321 MNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATL 380
            +PLETL++T   L E D+  L   PS+SQL  L+LS   L  +  EPL+ALLE+ +ATL
Sbjct: 292 KSPLETLALTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATL 351

Query: 381 QDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVL 440
           Q L   +CGI D +L  +LP+LS CS LTT  F+GN  S+  L+ LL+H   LSNL+   
Sbjct: 352 QTLFLVDCGIGDSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLET 411

Query: 441 YPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCG 491
           YP P ES  D  G +  E L  L A L  +L E+  P+ ++     CP CG
Sbjct: 412 YPAPRESL-DNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCG 461


>gi|12738831 PRAME family member 1 [Homo sapiens]
          Length = 474

 Score =  352 bits (904), Expect = 4e-97
 Identities = 216/483 (44%), Positives = 298/483 (61%), Gaps = 15/483 (3%)

Query: 22  SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81
           +P RL+ELAGQSLL+D+AL+I+A+E LPR L+ PLFM AF  RH QTL  MVQAWPFTCL
Sbjct: 5   APPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWPFTCL 64

Query: 82  PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141
           PLG LMK   LHLET KA+L+GL +LL Q+ RPRRWKLQVLDLR +  ++FW  W G  A
Sbjct: 65  PLGSLMKT--LHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLR-DVDENFWARWPGAWA 121

Query: 142 SLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKR 201
            L  FPE  +     K++  +      E    P++V +D+ LKE   DE   YL + V +
Sbjct: 122 -LSCFPETTS-----KRQTAEDCPRMGEHQ--PLKVFIDICLKEIPQDECLRYLFQWVYQ 173

Query: 202 KKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMIN 261
           ++ ++ LCC KL  +  P++ ++  LK++ L+SI++LE+        + K   YL +M N
Sbjct: 174 RRGLVHLCCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWPRLIRKLRCYLKEMKN 233

Query: 262 LRRLLLSHIHASSYISP-EKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHV 320
           LR+L+ S  H   Y S  E + + +A+F+S FL L+ LQ L +  + F  G L+QL+R +
Sbjct: 234 LRKLVFSRCH--HYTSDNELQGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCL 291

Query: 321 MNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATL 380
            NPLE L +T   L E D+  LSQ PS+  L  L+LS V+L  +S EPL ALLE+ +A+L
Sbjct: 292 QNPLENLELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASL 351

Query: 381 QDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVL 440
           + L+ + C I   QL A+LP+LS CSQLTT  F  N +SI AL+ LL+H  GLS L+   
Sbjct: 352 KTLILEGCQIHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLET 411

Query: 441 YPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFYDPEP 500
           YP P ES   +   ++ E    L A L   L E+ +P  +++   PCP CG     + E 
Sbjct: 412 YPAPEESLNSL-VRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELEL 470

Query: 501 ILC 503
            LC
Sbjct: 471 HLC 473


>gi|194306638 PRAME family member 3 [Homo sapiens]
          Length = 481

 Score =  352 bits (903), Expect = 5e-97
 Identities = 214/470 (45%), Positives = 293/470 (62%), Gaps = 13/470 (2%)

Query: 22  SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81
           +PRRL+ELAGQSLL D+ALAI+ L+ LPRELFPPLF+ AF  R  + LK MVQAWPF CL
Sbjct: 7   APRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWPFPCL 66

Query: 82  PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141
           PLG LMK   L  E    V+DG+D LLAQ+VRPRR KLQVL+LR +  ++FWT+WSG R 
Sbjct: 67  PLGSLMKTPDL--EILHYVVDGIDCLLAQKVRPRRRKLQVLELR-DVDENFWTIWSGARP 123

Query: 142 SLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKR 201
              S   PEA   M+K++ V+      E+   P++V +D+ LKE   DE  S+    V+ 
Sbjct: 124 LSCS---PEA---MSKRQTVEDCPRTGEKQ--PLKVFMDVCLKEKFMDEDLSFFSGWVQH 175

Query: 202 KKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMIN 261
           ++  + LCC K+  ++M + + + IL+ V  DSI+ LE+        + +F  YL QM N
Sbjct: 176 RRGSVHLCCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFIRYLSQMRN 235

Query: 262 LRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHVM 321
           LR+L +S       +S + +EQ +A+F+S  L L+ LQ LYV  + F RG LDQL+R + 
Sbjct: 236 LRKLFISD-GCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLR 294

Query: 322 NPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATLQ 381
           +PLETL++T   L + D+  L + PS+SQL  L+LS   L  +  EPL+ALLE+ +ATLQ
Sbjct: 295 SPLETLALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQ 354

Query: 382 DLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVLY 441
            L   +CGI D +L  +LP+LS CS LTT  F+GN  S+  L+ LL+H   LSNL+   Y
Sbjct: 355 TLFLVDCGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETY 414

Query: 442 PVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCG 491
           P P ES +D  G +  E L  L A L  +L E+  P  ++     CP CG
Sbjct: 415 PAPRESLDD-RGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCG 463


>gi|113865933 PRAME family member 16 [Homo sapiens]
          Length = 474

 Score =  352 bits (903), Expect = 5e-97
 Identities = 213/471 (45%), Positives = 285/471 (60%), Gaps = 15/471 (3%)

Query: 22  SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81
           SP RL+ELAGQSLL+++ L I  L+ LPRE+FP +FM A   RH + LK MVQAWPF  L
Sbjct: 5   SPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWPFLRL 64

Query: 82  PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141
           PLG LMK  HL  ET +AVL GLD LLAQ++RPRRWKLQVLDLR +   +FWT+WSG RA
Sbjct: 65  PLGSLMKTPHL--ETLQAVLKGLDTLLAQKLRPRRWKLQVLDLR-DVDGNFWTIWSGARA 121

Query: 142 SLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKR 201
              S   PEA   M K++ V+      E    P++V +DL  KE   DE  SYL   +  
Sbjct: 122 LSCS---PEA---MRKRQTVEDYPRTGEHQ--PLKVFIDLCQKESTLDECLSYLCRWIHY 173

Query: 202 KKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMIN 261
           ++ ++ LCC K++ ++MP    + +LK V  DSI++LE+     L    KF+PYL QM N
Sbjct: 174 RRGLVHLCCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSN 233

Query: 262 LRRLLLSHIHASS-YISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHV 320
           LR+L L+  +    Y+S +  +Q++      FL L   Q LY+  +  ++  L+ LLR +
Sbjct: 234 LRKLFLAFGYDDELYVSGQ--QQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCL 291

Query: 321 MNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATL 380
            NPL T    +  L++ D+  LSQ PS+SQL  L L  +++   + EPL ALLE+ +ATL
Sbjct: 292 KNPLGTFIFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATL 351

Query: 381 QDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVL 440
           + L   +C I D QL  LLP+LS CSQLTT  F GN  S +AL+ LL H  GLS L   L
Sbjct: 352 EILTLKDCQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLEL 411

Query: 441 YPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCG 491
           YP PLE   D  G ++ E LA + A L   L E+ +P  ++    PCP CG
Sbjct: 412 YPAPLECL-DNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCG 461


>gi|194306635 PRAME family member 19 [Homo sapiens]
          Length = 479

 Score =  349 bits (896), Expect = 3e-96
 Identities = 214/471 (45%), Positives = 294/471 (62%), Gaps = 15/471 (3%)

Query: 22  SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81
           +PRRL+ELAGQSLL+D+ALAI+ L+ LPRELFP LF+ AF  R  + LK MVQAWPF CL
Sbjct: 5   APRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWPFPCL 64

Query: 82  PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141
           PLG LMK   L  E    V+DG+D LLAQ+VRPRRWKLQVL++R +  ++FWT+WSG R 
Sbjct: 65  PLGSLMKTPDL--EILHYVVDGIDCLLAQKVRPRRWKLQVLEMR-DVDENFWTIWSGARP 121

Query: 142 SLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKR 201
              S   PEA   M+K++ V+      E+   P++V +D+ LKE + DE  S+    V+ 
Sbjct: 122 LSCS---PEA---MSKRQTVEDCPRTGEKQ--PLKVFMDVCLKEKSVDEDLSFFSGWVQH 173

Query: 202 KKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMIN 261
           ++  + LCC K+  ++M + + + IL+ V  DSI+ LE+        +A+ S YL QM N
Sbjct: 174 RRRSVHLCCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKN 233

Query: 262 LRRLLLSHIHASSYI-SPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHV 320
           LR+L +S      Y+ S E + Q +A+F+S FL L+ LQ LY+  + F  G LDQL+R +
Sbjct: 234 LRKLFISD--GCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCL 291

Query: 321 MNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATL 380
            +PLETL++T   L E D+  L   PS+SQL  L+LS   L  +  EPL+ALLE+ +ATL
Sbjct: 292 KSPLETLALTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATL 351

Query: 381 QDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVL 440
           Q L   +CGI   +L  +LP+LS CS LTT  F+GN  S+  L+ LL+H   LSNL+   
Sbjct: 352 QTLFLVDCGIGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLET 411

Query: 441 YPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCG 491
           YP P ES  D  G +  E L  L A L  +L E+  P+ ++     CP CG
Sbjct: 412 YPAPRESL-DNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCG 461


>gi|12738834 PRAME family member 2 [Homo sapiens]
          Length = 474

 Score =  341 bits (875), Expect = 8e-94
 Identities = 213/483 (44%), Positives = 291/483 (60%), Gaps = 15/483 (3%)

Query: 22  SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81
           +P RL+ELAGQSLL+D+AL+I+A+E LPR L+ PLF  AF  RH QTL  MVQAWPFTCL
Sbjct: 5   APPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFREAFSRRHFQTLTVMVQAWPFTCL 64

Query: 82  PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141
           PL  LMK   LHLE  KA+L+GL +LL Q+ RPRRWKLQVLDLR +  ++FW  W G  A
Sbjct: 65  PLVSLMKT--LHLEPLKALLEGLHMLLTQKDRPRRWKLQVLDLR-DVDENFWARWPGAWA 121

Query: 142 SLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKR 201
            L  FPE      M+K++  +      E    P++V +D+ LKE   DE   YL + V +
Sbjct: 122 -LSCFPEA-----MSKRQTAEDCPRTGEHQ--PLKVFIDICLKEIPQDECLRYLFQWVYQ 173

Query: 202 KKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMIN 261
           ++ ++ LCC KL  +  P++ ++  LK++ ++SI +LE+  T     + K   YL +M  
Sbjct: 174 RRGLVHLCCSKLVNYLTPIKYLRKSLKIIYINSIGELEIHNTCWPHLIRKLYCYLKEMKT 233

Query: 262 LRRLLLSHIHASSYISPEKEEQY-IAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHV 320
           L +L+ S  H   Y S  + E + + +FTS FL L+ LQ L +  + F  G L+QL+R +
Sbjct: 234 LCKLVFSRCH--HYTSDNELEGWLVTRFTSVFLRLEHLQLLKIKLITFFSGHLEQLIRCL 291

Query: 321 MNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATL 380
            NPLE L +T   L E D+  LSQ PS+  L  L+LS V+L  +S EPL ALLE+ +A+L
Sbjct: 292 QNPLENLELTCGNLLEEDLKCLSQFPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASL 351

Query: 381 QDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVL 440
           + LV + C I   QL A+LP LS CSQLTT  F  N +SI AL+ LL+H  GLS L+   
Sbjct: 352 ETLVLEGCQIHYSQLSAILPGLSCCSQLTTFYFGSNCMSIDALKDLLRHTSGLSKLSLET 411

Query: 441 YPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFYDPEP 500
           YP P ES   +   ++ E    L A L   L E  +P  +++   PCP CG     + E 
Sbjct: 412 YPAPEESLNSL-VRVNWEIFTPLRAELMCTLREFRQPKRIFIGPTPCPSCGSSPSEELEL 470

Query: 501 ILC 503
            LC
Sbjct: 471 HLC 473


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.137    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,184,959
Number of Sequences: 37866
Number of extensions: 826504
Number of successful extensions: 2235
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 51
Number of HSP's successfully gapped in prelim test: 27
Number of HSP's that attempted gapping in prelim test: 1996
Number of HSP's gapped (non-prelim): 133
length of query: 509
length of database: 18,247,518
effective HSP length: 107
effective length of query: 402
effective length of database: 14,195,856
effective search space: 5706734112
effective search space used: 5706734112
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.