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Search of human proteins with 46195765
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|46195765 unc-13 homolog D [Homo sapiens]
(1090 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|46195765 unc-13 homolog D [Homo sapiens] 2177 0.0
gi|15451914 BAI1-associated protein 3 [Homo sapiens] 571 e-162
gi|110611226 UNC13 (C. elegans)-like [Homo sapiens] 129 1e-29
gi|122937247 unc-13 homolog A [Homo sapiens] 99 2e-20
gi|122937514 unc-13 homolog C [Homo sapiens] 80 1e-14
gi|211059429 synaptotagmin II [Homo sapiens] 69 2e-11
gi|31543670 synaptotagmin II [Homo sapiens] 69 2e-11
gi|209447073 synaptotagmin I [Homo sapiens] 67 9e-11
gi|5032139 synaptotagmin I [Homo sapiens] 67 9e-11
gi|209447070 synaptotagmin I [Homo sapiens] 67 9e-11
gi|169202933 PREDICTED: similar to hCG21066 [Homo sapiens] 66 2e-10
gi|169203543 PREDICTED: similar to hCG21066 [Homo sapiens] 66 2e-10
gi|239744413 PREDICTED: hypothetical protein LOC390213 [Homo sap... 66 2e-10
gi|38570146 synaptotagmin VII [Homo sapiens] 65 5e-10
gi|92859638 synaptotagmin V [Homo sapiens] 64 6e-10
gi|238550198 synaptotagmin III [Homo sapiens] 60 1e-08
gi|238550196 synaptotagmin III [Homo sapiens] 60 1e-08
gi|14150054 synaptotagmin III [Homo sapiens] 60 1e-08
gi|45504376 synaptotagmin VI [Homo sapiens] 60 1e-08
gi|21361472 neural precursor cell expressed, developmentally dow... 56 2e-07
gi|222352090 neural precursor cell expressed, developmentally do... 56 2e-07
gi|222352088 neural precursor cell expressed, developmentally do... 56 2e-07
gi|222352086 neural precursor cell expressed, developmentally do... 56 2e-07
gi|39752671 synaptotagmin X [Homo sapiens] 56 2e-07
gi|4506067 protein kinase C, alpha [Homo sapiens] 55 4e-07
gi|47078261 double C2-like domains, alpha [Homo sapiens] 54 6e-07
gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens] 54 6e-07
gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens] 54 6e-07
gi|6005997 double C2-like domains, beta [Homo sapiens] 54 8e-07
gi|28376627 synaptotagmin IX [Homo sapiens] 54 1e-06
>gi|46195765 unc-13 homolog D [Homo sapiens]
Length = 1090
Score = 2177 bits (5641), Expect = 0.0
Identities = 1090/1090 (100%), Positives = 1090/1090 (100%)
Query: 1 MATLLSHPQQRPPFLRQAIKIRRRRVRDLQDPPPQMAPEIQPPSHHFSPEQRALLYEDAL 60
MATLLSHPQQRPPFLRQAIKIRRRRVRDLQDPPPQMAPEIQPPSHHFSPEQRALLYEDAL
Sbjct: 1 MATLLSHPQQRPPFLRQAIKIRRRRVRDLQDPPPQMAPEIQPPSHHFSPEQRALLYEDAL 60
Query: 61 YTVLHRLGHPEPNHVTEASELLRYLQEAFHVEPEEHQQTLQRVRELEKPIFCLKATVKQA 120
YTVLHRLGHPEPNHVTEASELLRYLQEAFHVEPEEHQQTLQRVRELEKPIFCLKATVKQA
Sbjct: 61 YTVLHRLGHPEPNHVTEASELLRYLQEAFHVEPEEHQQTLQRVRELEKPIFCLKATVKQA 120
Query: 121 KGILGKDVSGFSDPYCLLGIEQGVGVPGGSPGSRHRQKAVVRHTIPEEETHRTQVITQTL 180
KGILGKDVSGFSDPYCLLGIEQGVGVPGGSPGSRHRQKAVVRHTIPEEETHRTQVITQTL
Sbjct: 121 KGILGKDVSGFSDPYCLLGIEQGVGVPGGSPGSRHRQKAVVRHTIPEEETHRTQVITQTL 180
Query: 181 NPVWDETFILEFEDITNASFHLDMWDLDTVESVRQKLGELTDLHGLRRIFKEARKDKGQD 240
NPVWDETFILEFEDITNASFHLDMWDLDTVESVRQKLGELTDLHGLRRIFKEARKDKGQD
Sbjct: 181 NPVWDETFILEFEDITNASFHLDMWDLDTVESVRQKLGELTDLHGLRRIFKEARKDKGQD 240
Query: 241 DFLGNVVLRLQDLRCREDQWYPLEPRTETYPDRGQCHLQFQLIHKRRATSASRSQPSYTV 300
DFLGNVVLRLQDLRCREDQWYPLEPRTETYPDRGQCHLQFQLIHKRRATSASRSQPSYTV
Sbjct: 241 DFLGNVVLRLQDLRCREDQWYPLEPRTETYPDRGQCHLQFQLIHKRRATSASRSQPSYTV 300
Query: 301 HLHLLQQLVSHEVTQHEAGSTSWDGSLSPQAATVLFLHATQKDLSDFHQSMAQWLAYSRL 360
HLHLLQQLVSHEVTQHEAGSTSWDGSLSPQAATVLFLHATQKDLSDFHQSMAQWLAYSRL
Sbjct: 301 HLHLLQQLVSHEVTQHEAGSTSWDGSLSPQAATVLFLHATQKDLSDFHQSMAQWLAYSRL 360
Query: 361 YQSLEFPSSCLLHPITSIEYQWIQGRLKAEQQEELAASFSSLLTYGLSLIRRFRSVFPLS 420
YQSLEFPSSCLLHPITSIEYQWIQGRLKAEQQEELAASFSSLLTYGLSLIRRFRSVFPLS
Sbjct: 361 YQSLEFPSSCLLHPITSIEYQWIQGRLKAEQQEELAASFSSLLTYGLSLIRRFRSVFPLS 420
Query: 421 VSDSPARLQSLLRVLVQMCKMKAFGELCPNTAPLPQLVTEALQTGTTEWFHLKQQHHQPM 480
VSDSPARLQSLLRVLVQMCKMKAFGELCPNTAPLPQLVTEALQTGTTEWFHLKQQHHQPM
Sbjct: 421 VSDSPARLQSLLRVLVQMCKMKAFGELCPNTAPLPQLVTEALQTGTTEWFHLKQQHHQPM 480
Query: 481 VQGIPEAGKALLGLVQDVIGDLHQCQRTWDKIFHNTLKIHLFSMAFRELQWLVAKRVQDH 540
VQGIPEAGKALLGLVQDVIGDLHQCQRTWDKIFHNTLKIHLFSMAFRELQWLVAKRVQDH
Sbjct: 481 VQGIPEAGKALLGLVQDVIGDLHQCQRTWDKIFHNTLKIHLFSMAFRELQWLVAKRVQDH 540
Query: 541 TTVVGDVVSPEMGESLFQLYISLKELCQLRMSSSERDGVLALDNFHRWFQPAIPSWLQKT 600
TTVVGDVVSPEMGESLFQLYISLKELCQLRMSSSERDGVLALDNFHRWFQPAIPSWLQKT
Sbjct: 541 TTVVGDVVSPEMGESLFQLYISLKELCQLRMSSSERDGVLALDNFHRWFQPAIPSWLQKT 600
Query: 601 YNEALARVQRAVQMDELVPLGELTKHSTSAVDLSTCFAQISHTARQLDWPDPEEAFMITV 660
YNEALARVQRAVQMDELVPLGELTKHSTSAVDLSTCFAQISHTARQLDWPDPEEAFMITV
Sbjct: 601 YNEALARVQRAVQMDELVPLGELTKHSTSAVDLSTCFAQISHTARQLDWPDPEEAFMITV 660
Query: 661 KFVEDTCRLALVYCSLIKARARELSSGQKDQGQAANMLCVVVNDMEQLRLVIGKLPAQLA 720
KFVEDTCRLALVYCSLIKARARELSSGQKDQGQAANMLCVVVNDMEQLRLVIGKLPAQLA
Sbjct: 661 KFVEDTCRLALVYCSLIKARARELSSGQKDQGQAANMLCVVVNDMEQLRLVIGKLPAQLA 720
Query: 721 WEALEQRVGAVLEQGQLQNTLHAQLQSALAGLGHEIRTGVRTLAEQLEVGIAKHIQKLVG 780
WEALEQRVGAVLEQGQLQNTLHAQLQSALAGLGHEIRTGVRTLAEQLEVGIAKHIQKLVG
Sbjct: 721 WEALEQRVGAVLEQGQLQNTLHAQLQSALAGLGHEIRTGVRTLAEQLEVGIAKHIQKLVG 780
Query: 781 VRESVLPEDAILPLMKFLEVELCYMNTNLVQENFSSLLTLLWTHTLTVLVEAAASQRSSS 840
VRESVLPEDAILPLMKFLEVELCYMNTNLVQENFSSLLTLLWTHTLTVLVEAAASQRSSS
Sbjct: 781 VRESVLPEDAILPLMKFLEVELCYMNTNLVQENFSSLLTLLWTHTLTVLVEAAASQRSSS 840
Query: 841 LASNRLKIALQNLEICFHAEGCGLPPKALHTATFQALQRDLELQAASSRELIRKYFCSRI 900
LASNRLKIALQNLEICFHAEGCGLPPKALHTATFQALQRDLELQAASSRELIRKYFCSRI
Sbjct: 841 LASNRLKIALQNLEICFHAEGCGLPPKALHTATFQALQRDLELQAASSRELIRKYFCSRI 900
Query: 901 QQQAETTSEELGAVTVKASYRASEQKLRVELLSASSLLPLDSNGSSDPFVQLTLEPRHEF 960
QQQAETTSEELGAVTVKASYRASEQKLRVELLSASSLLPLDSNGSSDPFVQLTLEPRHEF
Sbjct: 901 QQQAETTSEELGAVTVKASYRASEQKLRVELLSASSLLPLDSNGSSDPFVQLTLEPRHEF 960
Query: 961 PELAARETQKHKKDLHPLFDETFEFLVPAEPCRKAGACLLLTVLDYDTLGADDLEGEAFL 1020
PELAARETQKHKKDLHPLFDETFEFLVPAEPCRKAGACLLLTVLDYDTLGADDLEGEAFL
Sbjct: 961 PELAARETQKHKKDLHPLFDETFEFLVPAEPCRKAGACLLLTVLDYDTLGADDLEGEAFL 1020
Query: 1021 PLREVPGLSGSEEPGEVPQTRLPLTYPAPNGDPILQLLEGRKGDREAQVFVRLRRHRAKQ 1080
PLREVPGLSGSEEPGEVPQTRLPLTYPAPNGDPILQLLEGRKGDREAQVFVRLRRHRAKQ
Sbjct: 1021 PLREVPGLSGSEEPGEVPQTRLPLTYPAPNGDPILQLLEGRKGDREAQVFVRLRRHRAKQ 1080
Query: 1081 ASQHALRPAP 1090
ASQHALRPAP
Sbjct: 1081 ASQHALRPAP 1090
>gi|15451914 BAI1-associated protein 3 [Homo sapiens]
Length = 1187
Score = 571 bits (1472), Expect = e-162
Identities = 370/1068 (34%), Positives = 565/1068 (52%), Gaps = 45/1068 (4%)
Query: 38 PEIQPPS---HHFSPEQRALLYEDALYTVLHRLGHPEPNHVTEASELLRYLQEAFHVEPE 94
PE PS +PE+ +LYE+ALYTVL+R G P+ V + LL YLQ+ F E
Sbjct: 119 PEPVDPSLGLRALAPEEVEMLYEEALYTVLYRAGTMGPDQVDDEEALLSYLQQVFGTSLE 178
Query: 95 EHQQTLQRVRELEKPIFCLKATVKQAKGILGKDVSGFSDPYCLLGIEQGVGVPGGSPGSR 154
EH + ++RVR+ + P + LK +V +AK +L KD +GFSDPYC+LGI P ++
Sbjct: 179 EHTEAIERVRKAKAPTYALKVSVMRAKNLLAKDPNGFSDPYCMLGILPASDATR-EPRAQ 237
Query: 155 HRQKAVVRH------TIPEEETHRTQVITQTLNPVWDETFILEFEDITNASFHLDMWDLD 208
Q+ R +P + T+V + TLNPVW E F+ E ED++ HLD+WD D
Sbjct: 238 KEQRFGFRKGSKRGGPLPAKCIQVTEVKSSTLNPVWKEHFLFEIEDVSTDQLHLDIWDHD 297
Query: 209 T----VESVRQKLGELTDLHGLRRIFKEARK-----------DKGQDDFLGNVVLRLQDL 253
VE+ R KL E+ L G+ R FK+ K + DDFLG + + ++++
Sbjct: 298 DDVSLVEACR-KLNEVIGLKGMGRYFKQIVKSARANGTAGPTEDHTDDFLGCLNIPVREV 356
Query: 254 RCRE-DQWYPLEPRTETYPDRGQCHLQFQLIHKRRATSAS-RSQPSYTVHLHLLQQLVSH 311
D+W+ LEPR+ +G CHL +LI +R T+ S R + + HL LL L+
Sbjct: 357 PVAGVDRWFKLEPRSSASRVQGHCHLVLKLITTQRDTAMSQRGRSGFLSHLLLLSHLLRL 416
Query: 312 EVTQHEAGSTSWDGSLSPQAATVLFLHATQKDLSDFHQSMAQWLAYSRLYQSLEFPSSCL 371
E + E S+SW G LS AAT+L LH Q +LS ++ W SR +Q+ S L
Sbjct: 417 EHSAEEPNSSSWRGELSTPAATILCLHGAQSNLSPLQLAVLHWQVSSRHHQTCTLDYSYL 476
Query: 372 LHPITSIEYQWIQG-RLKAEQQEELAASFSSLLTYGLSLIRRFRSVFPLSVSDSPARLQS 430
L + ++ W + L EQ+E LA S S+ +GL L+R+ R FP + S + RL+
Sbjct: 477 LGLLEDMQAHWEEAPSLPQEQEESLADSLSAFSEFGLQLLRQLRDYFPATNSTAVHRLEL 536
Query: 431 LLRVLVQMCKMKAFGELCPNTAPLPQLVTEALQTGTTEWFHLKQQHHQPMVQGIPEAGKA 490
LL+ L ++ + E+CP + L + AL+ G EW+ P Q P+
Sbjct: 537 LLKCLGKLQLFQPSFEICPFESELNMDIAAALKRGNREWYDRILNDKSPREQPGPQRLPG 596
Query: 491 LLGLVQDVIGDLHQCQRTWDKIFHNTLKIHLFSMAFRELQWLVAKRVQDHTTVVGDVVSP 550
L+ L V DL C + +FH+ L + +F++ FR+L+ LVA+ T + ++
Sbjct: 597 LVVLADAVYDDLQFCYSVYASLFHSILNVDVFTLTFRQLERLVAEEAWVLTEELSPKMTL 656
Query: 551 EMGESLFQLYISLKELCQLRMSSSERDG-VLALDNFHRWFQPAIPSWLQKTYNEALARVQ 609
E+ LF+LY++L +L + S RD LAL H F PA+ W Q ++A R+Q
Sbjct: 657 EVASGLFELYLTLADLQRFWDSIPGRDSRSLALAGIHAPFLPAVKLWFQVLRDQAKWRLQ 716
Query: 610 RAVQMDELVPLGELTKHSTSAVDLSTCFAQISHTARQLDWPDPEEAFMITVKFVEDTCRL 669
AV MD L P+ ++HS+SA C + I +L WPDP +A + + +D C
Sbjct: 717 GAVDMDTLEPVDASSRHSSSAATAGLCLSHIQELWVRLAWPDPAQAQGLGTQLGQDVCEA 776
Query: 670 ALVYCSLIKARARELSSGQKDQGQAAN-MLCVVVNDMEQLRLVIGKLPAQLAWEALEQRV 728
L Y L++ +++ + G+A + LCVV+N++E +R G+ LAW
Sbjct: 777 TLFYTELLR---KKVDTQPGAAGEAVSEALCVVLNNVELVRKAAGQALKGLAWPE----- 828
Query: 729 GAVLEQGQLQNTLHAQLQSALAGLGHEIRTGVRTLAEQLEVGIAKHIQKLVGVRESVLPE 788
GA +G L L + Q+ L E T L ++ I K++Q + +S+ +
Sbjct: 829 GATGPEGVLPRPLLSCTQALDDDLQREAHTVTAHLTSKMVGDIRKYVQHISLSPDSIQND 888
Query: 789 DAILPLMKFLEVELCYMNTNLVQENFSSLLTLLWTHTLTVLVEAAASQRSSSLAS-NRLK 847
+A+ PLMK+L+ +L +N +LV+ N S +L LW L +++A + R S +R
Sbjct: 889 EAVAPLMKYLDEKLALLNASLVKGNLSRVLEALWELLLQAILQALGANRDVSADFYSRFH 948
Query: 848 IALQNLEICFHAEGCGLPPKALHTATFQALQRDLELQAASSRELIRKYFCSRIQQQAETT 907
L+ L FHAEG GLP ++L +++ L+ +L L S+RE I +++ +++Q+
Sbjct: 949 FTLEALVSFFHAEGQGLPLESLRDGSYKRLKEELRLHKCSTRECIEQFYLDKLKQRT-LE 1007
Query: 908 SEELGAVTVKASYRASEQKLRVELLSASSLLPLDSNGSSDPFVQLTLEPRHEFPELAARE 967
G ++V+ Y A+EQ+L VE+L A+ LLPLD+NG SDPFV + L P H FP + ++
Sbjct: 1008 QNRFGRLSVRCHYEAAEQRLAVEVLHAADLLPLDANGLSDPFVIVELGPPHLFPLVRSQR 1067
Query: 968 TQKHKKDLHPLFDETFEFLVPAEPCRKAGACLLLTVLDYDTLGADDLEGEAFLPLREVPG 1027
TQ + LHP++DE F F VPAE CR+ AC+L TV+D+D L +D GEA L L V G
Sbjct: 1068 TQVKTRTLHPVYDELFYFSVPAEACRRRAACVLFTVMDHDWLSTNDFAGEAALGLGGVTG 1127
Query: 1028 LSGSEEPGEV---PQTRLPLTYPAPNGDPILQLLEGRKGDREAQVFVR 1072
++ + G L L P L+ LEGR +EAQ FV+
Sbjct: 1128 VARPQVGGGARAGQPVTLHLCRPRAQVRSALRRLEGRT-SKEAQEFVK 1174
>gi|110611226 UNC13 (C. elegans)-like [Homo sapiens]
Length = 1591
Score = 129 bits (325), Expect = 1e-29
Identities = 237/1100 (21%), Positives = 435/1100 (39%), Gaps = 187/1100 (17%)
Query: 80 ELLRYLQEAFHVEPEEHQQTLQRVRE-----LEKPIFCLKATVKQAKGILGKDVSGFSDP 134
E+ +++ F V H Q ++ V++ K + TV A+G+ KD +G SDP
Sbjct: 564 EIFEVIRDVFTVNKAAHVQQMKTVKQSVLDGTSKWSAKITITVVCAQGLQAKDKTGSSDP 623
Query: 135 YCLLGIEQGVGVPGGSPGSRHRQKAVVRHTIPEEETHRTQVITQTLNPVWDETFILEFED 194
Y + + + RT+ I LNPVW+E F E +
Sbjct: 624 YVTVQVSK--------------------------TKKRTKTIFGNLNPVWEEKFHFECHN 657
Query: 195 ITNASFHLDMWDLDTVESVRQKLGELTDLHGLRRIFKEARKDKGQDDFLGNVVLRLQDLR 254
++ + +WD D R K +R+ +E+ DDFLG ++ ++ L
Sbjct: 658 SSDR-IKVRVWDEDDDIKSRVK----------QRLKRES------DDFLGQTIIEVRTLS 700
Query: 255 CREDQWYPLEPRTETYPDRGQCHLQFQLIHKRRATSASRSQPSYTVHLHLLQQLV----S 310
D WY LE RT+ G LQ + K A +H +L L S
Sbjct: 701 GEMDVWYNLEKRTDKSAVSGAIRLQISVEIKGEEKVAPYHVQYTCLHENLFHYLTDIQGS 760
Query: 311 HEVTQHEA-GSTSWDGSLSPQAATVLFLHATQKDLSDFHQSMAQWLAYSRLYQSLEFPS- 368
V EA G +W A ++ A + + +Q+M + S Y P+
Sbjct: 761 GGVRIPEARGDDAWKVYFDETAQEIVDEFAMRYGIESIYQAMTHFACLSSKYMCPGVPAV 820
Query: 369 -SCLLHPITSIEYQWIQGRLKAEQQEELAAS------FSSLLTYGLSLIR----RFRSVF 417
S LL I + Y + AAS F LL + +R +R+ F
Sbjct: 821 MSTLLANINAY-YAHTTASTNVSASDRFAASNFGKERFVKLLDQLHNSLRIDLSTYRNNF 879
Query: 418 PLSVSDSPARLQSLLRVLVQMCKMKAFG------ELCPNTAPLPQLVTEALQTGTTEWF- 470
P + SP RLQ L + + + F + P + + + +A T E+
Sbjct: 880 P---AGSPERLQDLKSTVDLLTSITFFRMKVQELQSPPRASQVVKDCVKACLNSTYEYIF 936
Query: 471 ---HLKQQHHQPMVQGIP--EAGKALLGL------VQDVIGDLHQCQRTWDKIFH----- 514
H + Q +P E G ++ L + ++ + + + ++ + +
Sbjct: 937 NNCHDLYSRQYQLKQELPPEEQGPSIRNLDFWPKLITLIVSIIEEDKNSYTPVLNQFPQE 996
Query: 515 -NTLKI------HLFSMAFRELQWLVAKRVQDHTTVVGDVVSPEMGES-LFQLYISLKEL 566
N K+ HLF+ +++++ + + +DH D ++ L Y+ ++L
Sbjct: 997 LNVGKVSAEVMWHLFA---QDMKYALEEHEKDHLCKSADYMNLHFKVKWLHNEYV--RDL 1051
Query: 567 CQLRMSSSERDGVLALDNFHRWFQPAIPSWLQKTYNEALARVQRAVQMDELVPLGELTKH 626
L+ E + WF+ + WL + + +L ++ A++ D+ + ++H
Sbjct: 1052 PVLQGQVPE---------YPAWFEQFVLQWLDENEDVSLEFLRGALERDKKDGFQQTSEH 1102
Query: 627 ---STSAVDLSTCFAQISHTARQLDWPDPEEAFMITVKFVEDTCRLALVYCSLIKARARE 683
S S VD+ T Q R+L+ PDP +F + ++ + Y ++
Sbjct: 1103 ALFSCSVVDVFTQLNQSFEIIRKLECPDPSILAHYMRRFAKTIGKVLMQYADILSKDFPA 1162
Query: 684 LSSGQKDQGQAANMLCVVVNDMEQLRLVIGKLPAQLAWEALEQRVGAVLEQGQLQ-NTLH 742
+ +K + C+++N+++QLR+ + K+ + + L+ L++ Q++ NT+
Sbjct: 1163 YCTKEK-------LPCILMNNVQQLRVQLEKMFEAMGGKELDLEAADSLKELQVKLNTVL 1215
Query: 743 AQLQSALAGLGHEIRTG--VRTLAEQLE----VGIAKHIQKLVGVRESVLPEDAILPLMK 796
+L S + G ++R VR +A+ L G A + +++ + + PLM
Sbjct: 1216 DEL-SMVFGNSFQVRIDECVRQMADILGQVRGTGNASPDARASAAQDA---DSVLRPLMD 1271
Query: 797 FLEVELCYMNTNLVQENFSSLLTLLWT-----------------HTLTVLVEAAASQRS- 838
FL+ L T + +L LW T T L+ AA + S
Sbjct: 1272 FLDGNLTLFATVCEKTVLKRVLKELWRVVMNTMERMIVLPPLTDQTGTQLIFTAAKELSH 1331
Query: 839 -SSLASNRLK---------------IALQNLEICFHAEGCGLPPKALHTAT-FQALQRDL 881
S L + ++ +AL ++ FHA G GL L + Q+L+ L
Sbjct: 1332 LSKLKDHMVREETRNLTPKQCAVLDLALDTIKQYFHAGGNGLKKTFLEKSPDLQSLRYAL 1391
Query: 882 ELQAASSRELIRKYFCSRIQQQAETTSEELGAVTVKASY----RASEQKLRVELLSASSL 937
L ++ LI+ + S+ Q + +G V+++ E K+ V++++A+ L
Sbjct: 1392 SLYTQTTDTLIKTFVRSQTTQ-GSGVDDPVGEVSIQVDLFTHPGTGEHKVTVKVVAANDL 1450
Query: 938 LPLDSNGSSDPFVQLTLEPRHEFPELAARETQKHKKDLHPLFDETFEFLVPAEPCRKAGA 997
+ G PFV++T+ H+ + T+ + P ++ETF FL+ E ++
Sbjct: 1451 -KWQTAGMFRPFVEVTMVGPHQSDKKRKFTTKSKSNNWAPKYNETFHFLLGNEEGPESYE 1509
Query: 998 CLLLTVLDYDTLGADDLEGEAFLPLREVPGLSGSEEPGEVPQTRLPL---TYPAPNGDPI 1054
L + V DY D + G A +PLR+V PL + G I
Sbjct: 1510 -LQICVKDYCFAREDRVLGLAVMPLRDVTAKGSC-------ACWCPLGRKIHMDETGLTI 1561
Query: 1055 LQLLEGRKGDREAQVFVRLR 1074
L++L R D A+ FV+L+
Sbjct: 1562 LRILSQRSNDEVAREFVKLK 1581
>gi|122937247 unc-13 homolog A [Homo sapiens]
Length = 1791
Score = 99.4 bits (246), Expect = 2e-20
Identities = 233/1149 (20%), Positives = 420/1149 (36%), Gaps = 223/1149 (19%)
Query: 80 ELLRYLQEAFHVEPEEHQQTLQRVRE-----LEKPIFCLKATVKQAKGILGKDVSGFSDP 134
E+ +QE F V H Q ++ V++ K + TV A+G+ KD +G SDP
Sbjct: 728 EIFELIQEIFAVTKTAHTQQMKAVKQSVLDGTSKWSAKISITVVCAQGLQAKDKTGSSDP 787
Query: 135 YCLLGIEQGVGVPGGSPGSRHRQKAVVRHTIPEEETHRTQVITQTLNPVWDETFILEFED 194
Y + + + RT+ I LNPVW+E F E +
Sbjct: 788 YVTVQV--------------------------GKTKKRTKTIYGNLNPVWEENFHFECHN 821
Query: 195 ITNASFHLDMWDLDTVESVRQKLGELTDLHGLRRIFKEARKDKGQDDFLGNVVLRLQDLR 254
++ + +WD D + ++ ++ + R + DDFLG ++ ++ L
Sbjct: 822 -SSDRIKVRVWDED--DDIKSRV--------------KQRFKRESDDFLGQTIIEVRTLS 864
Query: 255 CREDQWYPLEPRTETYPDRGQCHLQFQLIHKRRATSASRSQPSYTVHLHLLQQLVSHEVT 314
D WY L+ RT+ G L + K A Y V L + + H VT
Sbjct: 865 GEMDVWYNLDKRTDKSAVSGAIRLHISVEIKGEEKVA-----PYHVQYTCLHENLFHFVT 919
Query: 315 QHE----------AGSTSWDGSLSPQAATVLFLHATQKDLSDFHQSMAQWLAYSRLYQSL 364
+ G +W A ++ A + + +Q+M + S Y
Sbjct: 920 DVQNNGVVKIPDAKGDDAWKVYYDETAQEIVDEFAMRYGVESIYQAMTHFACLSSKYMCP 979
Query: 365 EFPS--SCLLHPITSIEYQWIQGRLKAEQQEELAAS------FSSLLTYGLSLIR----R 412
P+ S LL I + Y + AAS F LL + +R
Sbjct: 980 GVPAVMSTLLANINAY-YAHTTASTNVSASDRFAASNFGKERFVKLLDQLHNSLRIDLSM 1038
Query: 413 FRSVFPLSVSDSPARLQSL------------LRVLVQMCK--------MKAFGELCPNTA 452
+R+ FP S SP RLQ L R+ VQ + +K + C N+
Sbjct: 1039 YRNNFPAS---SPERLQDLKSTVDLLTSITFFRMKVQELQSPPRASQVVKDCVKACLNST 1095
Query: 453 ------PLPQLVTEALQTGTTEWFHLKQQHHQPMVQGIPEAGKALLGLVQDVIGDLHQCQ 506
+L + QT + + + P ++ + K L+ L+ +I +
Sbjct: 1096 YEYIFNNCHELYSREYQTDPAKKGEVLPEEQGPSIKNLDFWSK-LITLIVSIIEEDKNSY 1154
Query: 507 RTWDKIFHNTLKIHLFSMAFRELQWLVAKRVQDHTTVVGDVVSPEMGESLFQLYISLKEL 566
F L + S E+ W + + + D L+ +K L
Sbjct: 1155 TPCLNQFPQELNVGKIS---AEVMWNLFAQDMKYAMEEHDKHRLCKSADYMNLHFKVKWL 1211
Query: 567 CQLRMSS--SERDGVLALDNFHRWFQPAIPSWLQKTYNEALAR--VQRAVQMDELVPLGE 622
++ + +D V + WF+P + WL + NE ++R + A++ D+ +
Sbjct: 1212 YNEYVTELPAFKDRV---PEYPAWFEPFVIQWLDE--NEEVSRDFLHGALERDKKDGFQQ 1266
Query: 623 LTKH---STSAVDLSTCFAQISHTARQLDWPDPEEAFMITVKFVEDTCRLALVYCSLIKA 679
++H S S VD+ + Q ++L+ PDP+ +F + + L Y +I
Sbjct: 1267 TSEHALFSCSVVDVFSQLNQSFEIIKKLECPDPQIVGHYMRRFAKTISNVLLQYADIISK 1326
Query: 680 RARELSSGQKDQGQAANMLCVVVNDMEQLRLVIGKLPAQLAWEALEQRVGAVLEQGQLQN 739
S +K++ + C+++N+ +QLR+ + K+ + + L+ +L++
Sbjct: 1327 DFASYCSKEKEK-----VPCILMNNTQQLRVQLEKMFEAMGGKELDAEASDILKE----- 1376
Query: 740 TLHAQLQSALAGLGHEIRTGVRTLAEQLEVGIAKHIQKLVGVRE------SVLPEDA--- 790
L +L + L L T + E+ + + ++ G S + +DA
Sbjct: 1377 -LQVKLNNVLDELSRVFATSFQPHIEECVKQMGDILSQVKGTGNVPASACSSVAQDADNV 1435
Query: 791 ILPLMKFLEVELCYMNTNLVQENFSSLLTLLW-----THTLTVLVEAAASQ--------- 836
+ P+M L+ L + +L LW T T+++ Q
Sbjct: 1436 LQPIMDLLDSNLTLFAKICEKTVLKRVLKELWKLVMNTMEKTIVLPPLTDQTMIGNLLRK 1495
Query: 837 RSSSLASNRLKIALQN--LEICFHA-----------------EGCGLPPK-------ALH 870
L R+K+ + ++ F+A E L PK AL
Sbjct: 1496 HGKGLEKGRVKLPSHSDGTQMIFNAAKELGQLSKLKDHMVREEAKSLTPKQCAVVELALD 1555
Query: 871 TAT--FQA---------LQRDLELQA--------ASSRELIRKYFCSRIQQQAETTSEEL 911
T F A L++ +LQ+ + +L+ K F Q + +
Sbjct: 1556 TIKQYFHAGGVGLKKTFLEKSPDLQSLRYALSLYTQATDLLIKTFVQTQSAQGLGVEDPV 1615
Query: 912 GAVTVKASY----RASEQKLRVELLSASSLLPLDSNGSSDPFVQLTLEPRHEFPELAARE 967
G V+V E K+ V++++A+ L ++G PF+++ + +
Sbjct: 1616 GEVSVHVELFTHPGTGEHKVTVKVVAAND-LKWQTSGIFRPFIEVNIIGPQLSDKKRKFA 1674
Query: 968 TQKHKKDLHPLFDETFEFLVPAE---PCRKAGACLLLTVLDYDTLGADDLEGEAFLPLRE 1024
T+ P ++E+F+F + A+ C + C V DY D G A L LRE
Sbjct: 1675 TKSKNNSWAPKYNESFQFTLSADAGPECYELQVC----VKDYCFAREDRTVGLAVLQLRE 1730
Query: 1025 VPGLSGSEEPGEVPQTRLPL---TYPAPNGDPILQLLEGRKGDREAQVFVRLRRHRAKQA 1081
+ + LPL + G +L++L R D A+ FV+L+ + A
Sbjct: 1731 LAQRGSA-------ACWLPLGRRIHMDDTGLTVLRILSQRSNDEVAKEFVKLKSD-TRSA 1782
Query: 1082 SQHALRPAP 1090
+ PAP
Sbjct: 1783 EEGGAAPAP 1791
>gi|122937514 unc-13 homolog C [Homo sapiens]
Length = 2214
Score = 79.7 bits (195), Expect = 1e-14
Identities = 107/542 (19%), Positives = 223/542 (41%), Gaps = 66/542 (12%)
Query: 581 ALDNFHRWFQPAIPSWLQKTYNEALARVQRAVQMDELVPLGELTKHSTSAVDLSTCFAQI 640
A+ + WF+P + WL + + ++ + A+ D+ + ++H+ + + FAQ+
Sbjct: 1681 AVPEYSLWFEPFVMQWLDENEDVSMEFLHGALGRDKKDGFQQTSEHALFSCSVVDVFAQL 1740
Query: 641 SHT---ARQLDWPDPEEAFMITVKFVEDTCRLALVYCSLIKARARELSSGQKDQGQAANM 697
+ + ++L+ P+PE + +F + ++ L Y +++ SS N+
Sbjct: 1741 NQSFEIIKKLECPNPEALSHLMRRFAKTINKVLLQYAAIV-------SSDFSSHCDKENV 1793
Query: 698 LCVVVNDMEQLRLVIGKLPAQLAWEALEQRVGAVLEQGQLQNTLHAQLQSALAGLGHEIR 757
C+++N+++QLR+ + K+ + + L+ +L+ +LQ L L G +
Sbjct: 1794 PCILMNNIQQLRVQLEKMFESMGGKELDSEASTILK--ELQVKLSGVLDELSVTYGESFQ 1851
Query: 758 TGVRTLAEQL--EVGIAKHIQKLVGVRESVLPEDAIL--PLMKFLEVELCYMNTNLVQEN 813
+ +Q+ E+ + + S + I+ LM FL+ L +
Sbjct: 1852 VIIEECIKQMSFELNQMRANGNTTSNKNSAAMDAEIVLRSLMDFLDKTLSLSAKICEKTV 1911
Query: 814 FSSLLTLLWTHTLT-------------------VLVEAAASQRSSSLASNRLK------- 847
+L LW L + + A + S L + ++
Sbjct: 1912 LKRVLKELWKLVLNKIEKQIVLPPLTDQTGPQMIFIAAKDLGQLSKLKEHMIREDARGLT 1971
Query: 848 --------IALQNLEICFHAEGCGLPPKALH-TATFQALQRDLELQAASSRELIRKYFCS 898
+ L ++ FHA G GL L + Q+L+ L L ++ LI+K+ +
Sbjct: 1972 PRQCAIMEVVLATIKQYFHAGGNGLKKNFLEKSPDLQSLRYALSLYTQTTDALIKKFIDT 2031
Query: 899 RIQQQAETTSEELGAVTVKASYRAS----EQKLRVELLSASSLLPLDSNGSSDPFVQLTL 954
+ Q+ ++ + +G ++V A+ + K+ V++++ + L + PFV++ +
Sbjct: 2032 Q-TSQSRSSKDAVGQISVHVDITATPGTGDHKVTVKVIAIND-LNWQTTAMFRPFVEVCI 2089
Query: 955 EPRHEFPELAARETQKHKKDLHPLFDETFEFLVPAEPCRKAGACLLLTVLDYDTLGADDL 1014
+ + + T+ P ++ETF+F++ E R L L+V DY D +
Sbjct: 2090 LGPNLGDKKRKQGTKTKSNTWSPKYNETFQFILGKEN-RPGAYELHLSVKDYCFAREDRI 2148
Query: 1015 EGEAFLPLREV--PGLSGSEEPGEVPQTRLPLTYPAPNGDPILQLLEGRKGDREAQVFVR 1072
G + L+ + G G+ P L G IL++L R D A+ FVR
Sbjct: 2149 IGMTVIQLQNIAEKGSYGAWYP------LLKNISMDETGLTILRILSQRTSDDVAKEFVR 2202
Query: 1073 LR 1074
L+
Sbjct: 2203 LK 2204
Score = 67.0 bits (162), Expect = 9e-11
Identities = 88/410 (21%), Positives = 157/410 (38%), Gaps = 76/410 (18%)
Query: 57 EDALYTVLHRLGHPEPNHVTEASELLRYLQEAFHVEPEEHQQTLQRVRE-----LEKPIF 111
ED T++ + E+ +QE F + E+ Q + ++ K
Sbjct: 1161 EDKTQTIITAMKERMKIREKNRPEVFEVIQEMFQISKEDFVQFTKAAKQSVLDGTSKWSA 1220
Query: 112 CLKATVKQAKGILGKDVSGFSDPYCLLGIEQGVGVPGGSPGSRHRQKAVVRHTIPEEETH 171
+ TV A+G+ KD +G SDPY + + G R
Sbjct: 1221 KITITVVSAQGLQAKDKTGSSDPYVTVQV-----------GKNKR--------------- 1254
Query: 172 RTQVITQTLNPVWDETFILEFEDITNASFHLDMWDLDTVESVRQKLGELTDLHGLRRIFK 231
RT+ I LNPVWDE F E + T+ + +WD D + ++ ++ ++ FK
Sbjct: 1255 RTKTIFGNLNPVWDEKFYFECHNSTDR-IKVRVWDED--DDIKSRV---------KQHFK 1302
Query: 232 EARKDKGQDDFLGNVVLRLQDLRCREDQWYPLEPRTETYPDRGQCHLQFQLIHKRRATSA 291
K DDFLG ++ ++ L D WY LE RT+ G L+ + K A
Sbjct: 1303 -----KESDDFLGQTIVEVRTLSGEMDVWYNLEKRTDKSAVSGAIRLKINVEIKGEEKVA 1357
Query: 292 SRSQPSYTVHLHLLQQLVSHEVTQHEA----------GSTSWDGSLSPQAATVLFLHATQ 341
Y + L + + H +T+ ++ G +W + ++ A +
Sbjct: 1358 -----PYHIQYTCLHENLFHYLTEVKSNGGVKIPEVKGDEAWKVFFDDASQEIVDEFAMR 1412
Query: 342 KDLSDFHQSMAQWLAYSRLYQSLEFPS--SCLLHPITSI-EYQWIQGRLKAEQQEELAAS 398
+ +Q+M + S Y P+ S LL I + + + ++ + AA+
Sbjct: 1413 YGIESIYQAMTHFSCLSSKYMCPGVPAVMSTLLANINAFYAHTTVSTNIQVSASDRFAAT 1472
Query: 399 ------FSSLLTYGLSLIR----RFRSVFPLSVSDSPARLQSLLRVLVQM 438
F LL + +R ++R FP S ++ L+S + +L +
Sbjct: 1473 NFGREKFIKLLDQLHNSLRIDLSKYRENFPASNTERLQDLKSTVDLLTSI 1522
Score = 32.3 bits (72), Expect = 2.5
Identities = 19/60 (31%), Positives = 31/60 (51%), Gaps = 7/60 (11%)
Query: 926 KLRVELLSASSLLPLDSNGSSDPFVQLTLEPRHEFPELAARETQKHKKDLHPLFDETFEF 985
K+ + ++SA L D GSSDP+V + + R T+ +L+P++DE F F
Sbjct: 1221 KITITVVSAQGLQAKDKTGSSDPYVTVQVGKN-------KRRTKTIFGNLNPVWDEKFYF 1273
>gi|211059429 synaptotagmin II [Homo sapiens]
Length = 419
Score = 68.9 bits (167), Expect = 2e-11
Identities = 41/123 (33%), Positives = 63/123 (51%), Gaps = 6/123 (4%)
Query: 903 QAETTSEELGAVTVKASYRASEQKLRVELLSASSLLPLDSNGSSDPFVQLTLEPRHEFPE 962
+ E E LG + Y +L V +L A+ L LD G+SDP+V++ L P +
Sbjct: 132 EEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLP----DK 187
Query: 963 LAARETQKHKKDLHPLFDETFEFLVPAEPCRKAGACLLLTVLDYDTLGADDLEGEAFLPL 1022
ET+ H+K L+P F+ETF F VP + G L++ + D+D D+ GE +P+
Sbjct: 188 KKKYETKVHRKTLNPAFNETFTFKVPYQ--ELGGKTLVMAIYDFDRFSKHDIIGEVKVPM 245
Query: 1023 REV 1025
V
Sbjct: 246 NTV 248
Score = 67.0 bits (162), Expect = 9e-11
Identities = 40/112 (35%), Positives = 64/112 (57%), Gaps = 4/112 (3%)
Query: 909 EELGAVTVKASYRASEQKLRVELLSASSLLPLDSNGSSDPFVQLTLEPRHEFPELAARET 968
E+LG + Y + KL V +L A +L +D G SDP+V++ L + L ++T
Sbjct: 269 EKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGK--RLKKKKT 326
Query: 969 QKHKKDLHPLFDETFEFLVPAEPCRKAGACLLLTVLDYDTLGADDLEGEAFL 1020
KK L+P F+E+F F +P E +K +++TVLDYD LG ++ G+ F+
Sbjct: 327 TVKKKTLNPYFNESFSFEIPFEQIQKVQ--VVVTVLDYDKLGKNEAIGKIFV 376
Score = 34.7 bits (78), Expect = 0.50
Identities = 28/98 (28%), Positives = 42/98 (42%), Gaps = 23/98 (23%)
Query: 113 LKATVKQAKGILGKDVSGFSDPYCLLGIEQGVGVPGGSPGSRHRQKAVVRHTIPEEETHR 172
L + +AK + DV G SDPY + + Q G R ++K +
Sbjct: 287 LTVCILEAKNLKKMDVGGLSDPYVKIHLMQN--------GKRLKKK-------------K 325
Query: 173 TQVITQTLNPVWDETFILE--FEDITNASFHLDMWDLD 208
T V +TLNP ++E+F E FE I + + D D
Sbjct: 326 TTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYD 363
>gi|31543670 synaptotagmin II [Homo sapiens]
Length = 419
Score = 68.9 bits (167), Expect = 2e-11
Identities = 41/123 (33%), Positives = 63/123 (51%), Gaps = 6/123 (4%)
Query: 903 QAETTSEELGAVTVKASYRASEQKLRVELLSASSLLPLDSNGSSDPFVQLTLEPRHEFPE 962
+ E E LG + Y +L V +L A+ L LD G+SDP+V++ L P +
Sbjct: 132 EEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLP----DK 187
Query: 963 LAARETQKHKKDLHPLFDETFEFLVPAEPCRKAGACLLLTVLDYDTLGADDLEGEAFLPL 1022
ET+ H+K L+P F+ETF F VP + G L++ + D+D D+ GE +P+
Sbjct: 188 KKKYETKVHRKTLNPAFNETFTFKVPYQ--ELGGKTLVMAIYDFDRFSKHDIIGEVKVPM 245
Query: 1023 REV 1025
V
Sbjct: 246 NTV 248
Score = 67.0 bits (162), Expect = 9e-11
Identities = 40/112 (35%), Positives = 64/112 (57%), Gaps = 4/112 (3%)
Query: 909 EELGAVTVKASYRASEQKLRVELLSASSLLPLDSNGSSDPFVQLTLEPRHEFPELAARET 968
E+LG + Y + KL V +L A +L +D G SDP+V++ L + L ++T
Sbjct: 269 EKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGK--RLKKKKT 326
Query: 969 QKHKKDLHPLFDETFEFLVPAEPCRKAGACLLLTVLDYDTLGADDLEGEAFL 1020
KK L+P F+E+F F +P E +K +++TVLDYD LG ++ G+ F+
Sbjct: 327 TVKKKTLNPYFNESFSFEIPFEQIQKVQ--VVVTVLDYDKLGKNEAIGKIFV 376
Score = 34.7 bits (78), Expect = 0.50
Identities = 28/98 (28%), Positives = 42/98 (42%), Gaps = 23/98 (23%)
Query: 113 LKATVKQAKGILGKDVSGFSDPYCLLGIEQGVGVPGGSPGSRHRQKAVVRHTIPEEETHR 172
L + +AK + DV G SDPY + + Q G R ++K +
Sbjct: 287 LTVCILEAKNLKKMDVGGLSDPYVKIHLMQN--------GKRLKKK-------------K 325
Query: 173 TQVITQTLNPVWDETFILE--FEDITNASFHLDMWDLD 208
T V +TLNP ++E+F E FE I + + D D
Sbjct: 326 TTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYD 363
>gi|209447073 synaptotagmin I [Homo sapiens]
Length = 422
Score = 67.0 bits (162), Expect = 9e-11
Identities = 40/121 (33%), Positives = 66/121 (54%), Gaps = 4/121 (3%)
Query: 900 IQQQAETTSEELGAVTVKASYRASEQKLRVELLSASSLLPLDSNGSSDPFVQLTLEPRHE 959
+Q + E+LG + Y + KL V +L A +L +D G SDP+V++ L +
Sbjct: 263 LQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGK 322
Query: 960 FPELAARETQKHKKDLHPLFDETFEFLVPAEPCRKAGACLLLTVLDYDTLGADDLEGEAF 1019
L ++T K L+P ++E+F F VP E +K +++TVLDYD +G +D G+ F
Sbjct: 323 --RLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQ--VVVTVLDYDKIGKNDAIGKVF 378
Query: 1020 L 1020
+
Sbjct: 379 V 379
Score = 65.1 bits (157), Expect = 3e-10
Identities = 39/125 (31%), Positives = 64/125 (51%), Gaps = 6/125 (4%)
Query: 901 QQQAETTSEELGAVTVKASYRASEQKLRVELLSASSLLPLDSNGSSDPFVQLTLEPRHEF 960
+++ E+LG + Y +L V ++ A+ L LD G+SDP+V++ L P +
Sbjct: 133 EKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKK- 191
Query: 961 PELAARETQKHKKDLHPLFDETFEFLVPAEPCRKAGACLLLTVLDYDTLGADDLEGEAFL 1020
ET+ H+K L+P+F+E F F VP G L++ V D+D D+ GE +
Sbjct: 192 ---KKFETKVHRKTLNPVFNEQFTFKVPYSEL--GGKTLVMAVYDFDRFSKHDIIGEFKV 246
Query: 1021 PLREV 1025
P+ V
Sbjct: 247 PMNTV 251
Score = 35.4 bits (80), Expect = 0.30
Identities = 27/100 (27%), Positives = 42/100 (42%), Gaps = 23/100 (23%)
Query: 113 LKATVKQAKGILGKDVSGFSDPYCLLGIEQGVGVPGGSPGSRHRQKAVVRHTIPEEETHR 172
L + +AK + DV G SDPY + + Q G R ++K +
Sbjct: 290 LTVVILEAKNLKKMDVGGLSDPYVKIHLMQN--------GKRLKKK-------------K 328
Query: 173 TQVITQTLNPVWDETFILE--FEDITNASFHLDMWDLDTV 210
T + TLNP ++E+F E FE I + + D D +
Sbjct: 329 TTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKI 368
>gi|5032139 synaptotagmin I [Homo sapiens]
Length = 422
Score = 67.0 bits (162), Expect = 9e-11
Identities = 40/121 (33%), Positives = 66/121 (54%), Gaps = 4/121 (3%)
Query: 900 IQQQAETTSEELGAVTVKASYRASEQKLRVELLSASSLLPLDSNGSSDPFVQLTLEPRHE 959
+Q + E+LG + Y + KL V +L A +L +D G SDP+V++ L +
Sbjct: 263 LQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGK 322
Query: 960 FPELAARETQKHKKDLHPLFDETFEFLVPAEPCRKAGACLLLTVLDYDTLGADDLEGEAF 1019
L ++T K L+P ++E+F F VP E +K +++TVLDYD +G +D G+ F
Sbjct: 323 --RLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQ--VVVTVLDYDKIGKNDAIGKVF 378
Query: 1020 L 1020
+
Sbjct: 379 V 379
Score = 65.1 bits (157), Expect = 3e-10
Identities = 39/125 (31%), Positives = 64/125 (51%), Gaps = 6/125 (4%)
Query: 901 QQQAETTSEELGAVTVKASYRASEQKLRVELLSASSLLPLDSNGSSDPFVQLTLEPRHEF 960
+++ E+LG + Y +L V ++ A+ L LD G+SDP+V++ L P +
Sbjct: 133 EKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKK- 191
Query: 961 PELAARETQKHKKDLHPLFDETFEFLVPAEPCRKAGACLLLTVLDYDTLGADDLEGEAFL 1020
ET+ H+K L+P+F+E F F VP G L++ V D+D D+ GE +
Sbjct: 192 ---KKFETKVHRKTLNPVFNEQFTFKVPYSEL--GGKTLVMAVYDFDRFSKHDIIGEFKV 246
Query: 1021 PLREV 1025
P+ V
Sbjct: 247 PMNTV 251
Score = 35.4 bits (80), Expect = 0.30
Identities = 27/100 (27%), Positives = 42/100 (42%), Gaps = 23/100 (23%)
Query: 113 LKATVKQAKGILGKDVSGFSDPYCLLGIEQGVGVPGGSPGSRHRQKAVVRHTIPEEETHR 172
L + +AK + DV G SDPY + + Q G R ++K +
Sbjct: 290 LTVVILEAKNLKKMDVGGLSDPYVKIHLMQN--------GKRLKKK-------------K 328
Query: 173 TQVITQTLNPVWDETFILE--FEDITNASFHLDMWDLDTV 210
T + TLNP ++E+F E FE I + + D D +
Sbjct: 329 TTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKI 368
>gi|209447070 synaptotagmin I [Homo sapiens]
Length = 422
Score = 67.0 bits (162), Expect = 9e-11
Identities = 40/121 (33%), Positives = 66/121 (54%), Gaps = 4/121 (3%)
Query: 900 IQQQAETTSEELGAVTVKASYRASEQKLRVELLSASSLLPLDSNGSSDPFVQLTLEPRHE 959
+Q + E+LG + Y + KL V +L A +L +D G SDP+V++ L +
Sbjct: 263 LQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGK 322
Query: 960 FPELAARETQKHKKDLHPLFDETFEFLVPAEPCRKAGACLLLTVLDYDTLGADDLEGEAF 1019
L ++T K L+P ++E+F F VP E +K +++TVLDYD +G +D G+ F
Sbjct: 323 --RLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQ--VVVTVLDYDKIGKNDAIGKVF 378
Query: 1020 L 1020
+
Sbjct: 379 V 379
Score = 65.1 bits (157), Expect = 3e-10
Identities = 39/125 (31%), Positives = 64/125 (51%), Gaps = 6/125 (4%)
Query: 901 QQQAETTSEELGAVTVKASYRASEQKLRVELLSASSLLPLDSNGSSDPFVQLTLEPRHEF 960
+++ E+LG + Y +L V ++ A+ L LD G+SDP+V++ L P +
Sbjct: 133 EKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKK- 191
Query: 961 PELAARETQKHKKDLHPLFDETFEFLVPAEPCRKAGACLLLTVLDYDTLGADDLEGEAFL 1020
ET+ H+K L+P+F+E F F VP G L++ V D+D D+ GE +
Sbjct: 192 ---KKFETKVHRKTLNPVFNEQFTFKVPYSEL--GGKTLVMAVYDFDRFSKHDIIGEFKV 246
Query: 1021 PLREV 1025
P+ V
Sbjct: 247 PMNTV 251
Score = 35.4 bits (80), Expect = 0.30
Identities = 27/100 (27%), Positives = 42/100 (42%), Gaps = 23/100 (23%)
Query: 113 LKATVKQAKGILGKDVSGFSDPYCLLGIEQGVGVPGGSPGSRHRQKAVVRHTIPEEETHR 172
L + +AK + DV G SDPY + + Q G R ++K +
Sbjct: 290 LTVVILEAKNLKKMDVGGLSDPYVKIHLMQN--------GKRLKKK-------------K 328
Query: 173 TQVITQTLNPVWDETFILE--FEDITNASFHLDMWDLDTV 210
T + TLNP ++E+F E FE I + + D D +
Sbjct: 329 TTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKI 368
>gi|169202933 PREDICTED: similar to hCG21066 [Homo sapiens]
Length = 451
Score = 66.2 bits (160), Expect = 2e-10
Identities = 46/125 (36%), Positives = 67/125 (53%), Gaps = 6/125 (4%)
Query: 894 KYFCSRIQQQAETTS--EELGAVTVKASYRASEQKLRVELLSASSLLPLDSNGSSDPFVQ 951
K+ +R ++ ET EE G V + Y + + L V +L + L P+D+NG SDPFV+
Sbjct: 289 KHNSARSMEEVETEVAWEECGHVLLSLCYSSQQGGLLVGVLRCAHLAPMDANGYSDPFVR 348
Query: 952 LTLEPRHEFPELAARETQKHKKDLHPLFDETFEFLVPAEPCRKAGACLLLTVLDYDTLGA 1011
L L P + + +T H+K L+P F+E F + P E A LL++V DYD A
Sbjct: 349 LFLHP--NAGKKSKFKTSVHRKTLNPEFNEEFFYSGPRE--ELAQKTLLVSVWDYDLGTA 404
Query: 1012 DDLEG 1016
DD G
Sbjct: 405 DDFIG 409
>gi|169203543 PREDICTED: similar to hCG21066 [Homo sapiens]
Length = 451
Score = 66.2 bits (160), Expect = 2e-10
Identities = 46/125 (36%), Positives = 67/125 (53%), Gaps = 6/125 (4%)
Query: 894 KYFCSRIQQQAETTS--EELGAVTVKASYRASEQKLRVELLSASSLLPLDSNGSSDPFVQ 951
K+ +R ++ ET EE G V + Y + + L V +L + L P+D+NG SDPFV+
Sbjct: 289 KHNSARSMEEVETEVAWEECGHVLLSLCYSSQQGGLLVGVLRCAHLAPMDANGYSDPFVR 348
Query: 952 LTLEPRHEFPELAARETQKHKKDLHPLFDETFEFLVPAEPCRKAGACLLLTVLDYDTLGA 1011
L L P + + +T H+K L+P F+E F + P E A LL++V DYD A
Sbjct: 349 LFLHP--NAGKKSKFKTSVHRKTLNPEFNEEFFYSGPRE--ELAQKTLLVSVWDYDLGTA 404
Query: 1012 DDLEG 1016
DD G
Sbjct: 405 DDFIG 409
>gi|239744413 PREDICTED: hypothetical protein LOC390213 [Homo sapiens]
Length = 431
Score = 65.9 bits (159), Expect = 2e-10
Identities = 43/114 (37%), Positives = 61/114 (53%), Gaps = 4/114 (3%)
Query: 903 QAETTSEELGAVTVKASYRASEQKLRVELLSASSLLPLDSNGSSDPFVQLTLEPRHEFPE 962
+ E EE G V + Y + + L V +L + L P+D+NG SDPFV+L L P +
Sbjct: 280 ETEVAWEECGHVLLSLCYSSQQGGLLVGVLRCAHLAPMDANGYSDPFVRLFLHP--NAGK 337
Query: 963 LAARETQKHKKDLHPLFDETFEFLVPAEPCRKAGACLLLTVLDYDTLGADDLEG 1016
+ +T H+K L+P F+E F + P E A LL++V DYD ADD G
Sbjct: 338 KSKFKTSVHRKTLNPEFNEEFFYSGPRE--ELAQKTLLVSVWDYDLGTADDFIG 389
>gi|38570146 synaptotagmin VII [Homo sapiens]
Length = 403
Score = 64.7 bits (156), Expect = 5e-10
Identities = 34/116 (29%), Positives = 67/116 (57%), Gaps = 4/116 (3%)
Query: 912 GAVTVKASYRASEQKLRVELLSASSLLPLDSNGSSDPFVQLTLEPRHEFPELAARETQKH 971
G + + Y S + V ++ A +L +D G+SDP+V++ L ++ + ++T
Sbjct: 268 GELLLSLCYNPSANSIIVNIIKARNLKAMDIGGTSDPYVKVWL--MYKDKRVEKKKTVTM 325
Query: 972 KKDLHPLFDETFEFLVPAEPCRKAGACLLLTVLDYDTLGADDLEGEAFLPLREVPG 1027
K++L+P+F+E+F F +P E R+ +++TV+D D L +D+ G+ +L + PG
Sbjct: 326 KRNLNPIFNESFAFDIPTEKLRE--TTIIITVMDKDKLSRNDVIGKIYLSWKSGPG 379
Score = 62.0 bits (149), Expect = 3e-09
Identities = 43/120 (35%), Positives = 63/120 (52%), Gaps = 11/120 (9%)
Query: 909 EELGAVTVKASYRASEQKLRVELLSASSLLPLDSNGSSDPFVQLTLEP--RHEFPELAAR 966
E LG + Y E L V+++ A L D +G+SDPFV++ L P +H+
Sbjct: 134 ENLGRIQFSVGYNFQESTLTVKIMKAQELPAKDFSGTSDPFVKIYLLPDKKHKL------ 187
Query: 967 ETQKHKKDLHPLFDETFEFL-VPAEPCRKAGACLLLTVLDYDTLGADDLEGEAFLPLREV 1025
ET+ +K+L+P ++ETF F P E + L L VLDYD +D GE +PL +V
Sbjct: 188 ETKVKRKNLNPHWNETFLFEGFPYE--KVVQRILYLQVLDYDRFSRNDPIGEVSIPLNKV 245
Score = 36.2 bits (82), Expect = 0.17
Identities = 34/147 (23%), Positives = 62/147 (42%), Gaps = 33/147 (22%)
Query: 113 LKATVKQAKGILGKDVSGFSDPYCLLGIEQGVGVPGGSPGSRHRQKAVVRHTIPEEETHR 172
L + +A+ + KD SG SDP+ + + P +H+ +
Sbjct: 152 LTVKIMKAQELPAKDFSGTSDPFVKIYL---------LPDKKHKLE-------------- 188
Query: 173 TQVITQTLNPVWDETFILE---FEDITNASFHLDMWDLDTVESVRQKLGELT------DL 223
T+V + LNP W+ETF+ E +E + +L + D D S +GE++ DL
Sbjct: 189 TKVKRKNLNPHWNETFLFEGFPYEKVVQRILYLQVLDYDRF-SRNDPIGEVSIPLNKVDL 247
Query: 224 HGLRRIFKEARKDKGQDDFLGNVVLRL 250
++ +K+ + G ++L L
Sbjct: 248 TQMQTFWKDLKPCSDGSGSRGELLLSL 274
>gi|92859638 synaptotagmin V [Homo sapiens]
Length = 386
Score = 64.3 bits (155), Expect = 6e-10
Identities = 42/123 (34%), Positives = 59/123 (47%), Gaps = 6/123 (4%)
Query: 903 QAETTSEELGAVTVKASYRASEQKLRVELLSASSLLPLDSNGSSDPFVQLTLEPRHEFPE 962
Q ELG + Y +L V +L A L LD GSSDP+V++ L P +
Sbjct: 101 QQVADKHELGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLP----DK 156
Query: 963 LAARETQKHKKDLHPLFDETFEFLVPAEPCRKAGACLLLTVLDYDTLGADDLEGEAFLPL 1022
ET+ H++ L+P F ETF F VP G L++ V D+D +D GE +P+
Sbjct: 157 RRRYETKVHRQTLNPHFGETFAFKVPY--VELGGRVLVMAVYDFDRFSRNDAIGEVRVPM 214
Query: 1023 REV 1025
V
Sbjct: 215 SSV 217
Score = 58.2 bits (139), Expect = 4e-08
Identities = 38/117 (32%), Positives = 61/117 (52%), Gaps = 4/117 (3%)
Query: 900 IQQQAETTSEELGAVTVKASYRASEQKLRVELLSASSLLPLDSNGSSDPFVQLTLEPRHE 959
+Q E+LG + Y + KL V +L A +L +D G SDP+V++ L +
Sbjct: 229 LQAAPREEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGK 288
Query: 960 FPELAARETQKHKKDLHPLFDETFEFLVPAEPCRKAGACLLLTVLDYDTLGADDLEG 1016
++ ++T K L+P ++E F F VP + +K + LTVLDYD LG ++ G
Sbjct: 289 --KVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQ--VELTVLDYDKLGKNEAIG 341
Score = 33.9 bits (76), Expect = 0.86
Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 23/98 (23%)
Query: 113 LKATVKQAKGILGKDVSGFSDPYCLLGIEQGVGVPGGSPGSRHRQKAVVRHTIPEEETHR 172
L V +AK + DV G SDPY + + QG G + R+K +
Sbjct: 256 LTVIVLEAKNLKKMDVGGLSDPYVKVHLLQG--------GKKVRKK-------------K 294
Query: 173 TQVITQTLNPVWDETFILEF--EDITNASFHLDMWDLD 208
T + TLNP ++E F E + + L + D D
Sbjct: 295 TTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYD 332
>gi|238550198 synaptotagmin III [Homo sapiens]
Length = 590
Score = 60.1 bits (144), Expect = 1e-08
Identities = 39/114 (34%), Positives = 57/114 (50%), Gaps = 6/114 (5%)
Query: 907 TSEELGAVTVKASYRASEQKLRVELLSASSLLPLDSNGSSDPFVQLTLEPRHEFPELAAR 966
T G ++ Y +L V +L A L DSNG SDP+V++ L P +
Sbjct: 296 TGAPCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRK----KKF 351
Query: 967 ETQKHKKDLHPLFDETFEFLVPAEPCRKAGACLLLTVLDYDTLGADDLEGEAFL 1020
+T+ H+K L+P+F+ETF+F VP A L +V D+D DL G+ L
Sbjct: 352 QTKVHRKTLNPVFNETFQFSVPL--AELAQRKLHFSVYDFDRFSRHDLIGQVVL 403
Score = 53.1 bits (126), Expect = 1e-06
Identities = 34/107 (31%), Positives = 55/107 (51%), Gaps = 4/107 (3%)
Query: 910 ELGAVTVKASYRASEQKLRVELLSASSLLPLDSNGSSDPFVQLTLEPRHEFPELAARETQ 969
+LG + Y + +L V ++ AS+L +D G SDP+V+ +L E L R+T
Sbjct: 431 DLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASL--ISEGRRLKKRKTS 488
Query: 970 KHKKDLHPLFDETFEFLVPAEPCRKAGACLLLTVLDYDTLGADDLEG 1016
K L+P ++E F V E G L + V+DYD +G +++ G
Sbjct: 489 IKKNTLNPTYNEALVFDVAPESVENVG--LSIAVVDYDCIGHNEVIG 533
Score = 35.0 bits (79), Expect = 0.39
Identities = 26/99 (26%), Positives = 44/99 (44%), Gaps = 27/99 (27%)
Query: 113 LKATVKQAKGILGKDVSGFSDPYCLLGIEQGVGVPGGSPGSRHRQKAVVRHTIPE-EETH 171
L + QA + KD +GFSDPY V + +P+ ++
Sbjct: 316 LVVRILQALDLPAKDSNGFSDPY------------------------VKIYLLPDRKKKF 351
Query: 172 RTQVITQTLNPVWDET--FILEFEDITNASFHLDMWDLD 208
+T+V +TLNPV++ET F + ++ H ++D D
Sbjct: 352 QTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFD 390
Score = 32.7 bits (73), Expect = 1.9
Identities = 23/100 (23%), Positives = 42/100 (42%), Gaps = 23/100 (23%)
Query: 113 LKATVKQAKGILGKDVSGFSDPYCLLGIEQGVGVPGGSPGSRHRQKAVVRHTIPEEETHR 172
L T+ +A + D++GFSDPY + S G R +++ +
Sbjct: 448 LTVTIIKASNLKAMDLTGFSDPYVKASLI--------SEGRRLKKR-------------K 486
Query: 173 TQVITQTLNPVWDETFILEF--EDITNASFHLDMWDLDTV 210
T + TLNP ++E + + E + N + + D D +
Sbjct: 487 TSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCI 526
>gi|238550196 synaptotagmin III [Homo sapiens]
Length = 590
Score = 60.1 bits (144), Expect = 1e-08
Identities = 39/114 (34%), Positives = 57/114 (50%), Gaps = 6/114 (5%)
Query: 907 TSEELGAVTVKASYRASEQKLRVELLSASSLLPLDSNGSSDPFVQLTLEPRHEFPELAAR 966
T G ++ Y +L V +L A L DSNG SDP+V++ L P +
Sbjct: 296 TGAPCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRK----KKF 351
Query: 967 ETQKHKKDLHPLFDETFEFLVPAEPCRKAGACLLLTVLDYDTLGADDLEGEAFL 1020
+T+ H+K L+P+F+ETF+F VP A L +V D+D DL G+ L
Sbjct: 352 QTKVHRKTLNPVFNETFQFSVPL--AELAQRKLHFSVYDFDRFSRHDLIGQVVL 403
Score = 53.1 bits (126), Expect = 1e-06
Identities = 34/107 (31%), Positives = 55/107 (51%), Gaps = 4/107 (3%)
Query: 910 ELGAVTVKASYRASEQKLRVELLSASSLLPLDSNGSSDPFVQLTLEPRHEFPELAARETQ 969
+LG + Y + +L V ++ AS+L +D G SDP+V+ +L E L R+T
Sbjct: 431 DLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASL--ISEGRRLKKRKTS 488
Query: 970 KHKKDLHPLFDETFEFLVPAEPCRKAGACLLLTVLDYDTLGADDLEG 1016
K L+P ++E F V E G L + V+DYD +G +++ G
Sbjct: 489 IKKNTLNPTYNEALVFDVAPESVENVG--LSIAVVDYDCIGHNEVIG 533
Score = 35.0 bits (79), Expect = 0.39
Identities = 26/99 (26%), Positives = 44/99 (44%), Gaps = 27/99 (27%)
Query: 113 LKATVKQAKGILGKDVSGFSDPYCLLGIEQGVGVPGGSPGSRHRQKAVVRHTIPE-EETH 171
L + QA + KD +GFSDPY V + +P+ ++
Sbjct: 316 LVVRILQALDLPAKDSNGFSDPY------------------------VKIYLLPDRKKKF 351
Query: 172 RTQVITQTLNPVWDET--FILEFEDITNASFHLDMWDLD 208
+T+V +TLNPV++ET F + ++ H ++D D
Sbjct: 352 QTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFD 390
Score = 32.7 bits (73), Expect = 1.9
Identities = 23/100 (23%), Positives = 42/100 (42%), Gaps = 23/100 (23%)
Query: 113 LKATVKQAKGILGKDVSGFSDPYCLLGIEQGVGVPGGSPGSRHRQKAVVRHTIPEEETHR 172
L T+ +A + D++GFSDPY + S G R +++ +
Sbjct: 448 LTVTIIKASNLKAMDLTGFSDPYVKASLI--------SEGRRLKKR-------------K 486
Query: 173 TQVITQTLNPVWDETFILEF--EDITNASFHLDMWDLDTV 210
T + TLNP ++E + + E + N + + D D +
Sbjct: 487 TSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCI 526
>gi|14150054 synaptotagmin III [Homo sapiens]
Length = 590
Score = 60.1 bits (144), Expect = 1e-08
Identities = 39/114 (34%), Positives = 57/114 (50%), Gaps = 6/114 (5%)
Query: 907 TSEELGAVTVKASYRASEQKLRVELLSASSLLPLDSNGSSDPFVQLTLEPRHEFPELAAR 966
T G ++ Y +L V +L A L DSNG SDP+V++ L P +
Sbjct: 296 TGAPCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRK----KKF 351
Query: 967 ETQKHKKDLHPLFDETFEFLVPAEPCRKAGACLLLTVLDYDTLGADDLEGEAFL 1020
+T+ H+K L+P+F+ETF+F VP A L +V D+D DL G+ L
Sbjct: 352 QTKVHRKTLNPVFNETFQFSVPL--AELAQRKLHFSVYDFDRFSRHDLIGQVVL 403
Score = 53.1 bits (126), Expect = 1e-06
Identities = 34/107 (31%), Positives = 55/107 (51%), Gaps = 4/107 (3%)
Query: 910 ELGAVTVKASYRASEQKLRVELLSASSLLPLDSNGSSDPFVQLTLEPRHEFPELAARETQ 969
+LG + Y + +L V ++ AS+L +D G SDP+V+ +L E L R+T
Sbjct: 431 DLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASL--ISEGRRLKKRKTS 488
Query: 970 KHKKDLHPLFDETFEFLVPAEPCRKAGACLLLTVLDYDTLGADDLEG 1016
K L+P ++E F V E G L + V+DYD +G +++ G
Sbjct: 489 IKKNTLNPTYNEALVFDVAPESVENVG--LSIAVVDYDCIGHNEVIG 533
Score = 35.0 bits (79), Expect = 0.39
Identities = 26/99 (26%), Positives = 44/99 (44%), Gaps = 27/99 (27%)
Query: 113 LKATVKQAKGILGKDVSGFSDPYCLLGIEQGVGVPGGSPGSRHRQKAVVRHTIPE-EETH 171
L + QA + KD +GFSDPY V + +P+ ++
Sbjct: 316 LVVRILQALDLPAKDSNGFSDPY------------------------VKIYLLPDRKKKF 351
Query: 172 RTQVITQTLNPVWDET--FILEFEDITNASFHLDMWDLD 208
+T+V +TLNPV++ET F + ++ H ++D D
Sbjct: 352 QTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFD 390
Score = 32.7 bits (73), Expect = 1.9
Identities = 23/100 (23%), Positives = 42/100 (42%), Gaps = 23/100 (23%)
Query: 113 LKATVKQAKGILGKDVSGFSDPYCLLGIEQGVGVPGGSPGSRHRQKAVVRHTIPEEETHR 172
L T+ +A + D++GFSDPY + S G R +++ +
Sbjct: 448 LTVTIIKASNLKAMDLTGFSDPYVKASLI--------SEGRRLKKR-------------K 486
Query: 173 TQVITQTLNPVWDETFILEF--EDITNASFHLDMWDLDTV 210
T + TLNP ++E + + E + N + + D D +
Sbjct: 487 TSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCI 526
>gi|45504376 synaptotagmin VI [Homo sapiens]
Length = 425
Score = 60.1 bits (144), Expect = 1e-08
Identities = 49/160 (30%), Positives = 71/160 (44%), Gaps = 17/160 (10%)
Query: 861 GCGLPPKALHTATFQALQRDLELQAASSRELIRKYFCSRIQQQAETTSEELGAVTVKASY 920
G LPP A + ++ +L Q + E ++E T + G + Y
Sbjct: 106 GNELPPAAEQPTSIGRIKPELYKQKSVDGE----------DAKSEAT-KSCGKINFSLRY 154
Query: 921 RASEQKLRVELLSASSLLPLDSNGSSDPFVQLTLEPRHEFPELAARETQKHKKDLHPLFD 980
+ L V +L A L D GSSDP+V++ L P + +T+ H+K L+P FD
Sbjct: 155 DYETETLIVRILKAFDLPAKDFCGSSDPYVKIYLLPDRK----CKLQTRVHRKTLNPTFD 210
Query: 981 ETFEFLVPAEPCRKAGACLLLTVLDYDTLGADDLEGEAFL 1020
E F F VP E A L L+V D+D D+ GE L
Sbjct: 211 ENFHFPVPYE--ELADRKLHLSVFDFDRFSRHDMIGEVIL 248
Score = 52.8 bits (125), Expect = 2e-06
Identities = 32/115 (27%), Positives = 62/115 (53%), Gaps = 4/115 (3%)
Query: 902 QQAETTSEELGAVTVKASYRASEQKLRVELLSASSLLPLDSNGSSDPFVQLTLEPRHEFP 961
Q A + S +LG + Y + +L + ++ +L +D G SDP+V+++L +
Sbjct: 268 QYATSESVDLGEIMFSLCYLPTAGRLTLTVIKCRNLKAMDITGYSDPYVKVSL--LCDGR 325
Query: 962 ELAARETQKHKKDLHPLFDETFEFLVPAEPCRKAGACLLLTVLDYDTLGADDLEG 1016
L ++T K L+P+++E F +P E + LL++V+DYD +G +++ G
Sbjct: 326 RLKKKKTTIKKNTLNPVYNEAIIFDIPPENMDQVS--LLISVMDYDRVGHNEIIG 378
Score = 38.9 bits (89), Expect = 0.027
Identities = 61/279 (21%), Positives = 105/279 (37%), Gaps = 37/279 (13%)
Query: 6 SHPQQRPPFLR--QAIKIRRRRVRDLQDPPPQMAPEIQPPSHHFSPE-----QRALLYED 58
S P P L Q+ R L+DP E H SP+ Q ++
Sbjct: 9 SSPSSANPPLEALQSPSFRGNMADKLKDPSTLGFLEAAVKISHTSPDIPAEVQMSVKEHI 68
Query: 59 ALYTVLHRLGHPEPNHVTEASELLRYLQEAFHVEPEEHQQTLQRVRELEKPIFCLKATVK 118
+T L R EP T + R+L HV ++ L E I +K +
Sbjct: 69 MRHTRLQRQT-TEPASSTRHTSFKRHLPRQMHVSSVDYGNELPPAAEQPTSIGRIKPELY 127
Query: 119 QAKGILGKDVSGFSDPYC----------------LLGIEQGVGVPGGS-PGSRHRQKAVV 161
+ K + G+D + C ++ I + +P GS +
Sbjct: 128 KQKSVDGEDAKSEATKSCGKINFSLRYDYETETLIVRILKAFDLPAKDFCGSSDPYVKI- 186
Query: 162 RHTIPEEETH-RTQVITQTLNPVWDET--FILEFEDITNASFHLDMWDLDTV-------E 211
+ +P+ + +T+V +TLNP +DE F + +E++ + HL ++D D E
Sbjct: 187 -YLLPDRKCKLQTRVHRKTLNPTFDENFHFPVPYEELADRKLHLSVFDFDRFSRHDMIGE 245
Query: 212 SVRQKLGELTDLHGLRRIFKEARKDKGQDDFLGNVVLRL 250
+ L E +DL I+K+ + + LG ++ L
Sbjct: 246 VILDNLFEASDLSRETSIWKDIQYATSESVDLGEIMFSL 284
Score = 33.5 bits (75), Expect = 1.1
Identities = 27/100 (27%), Positives = 44/100 (44%), Gaps = 23/100 (23%)
Query: 113 LKATVKQAKGILGKDVSGFSDPYCLLGIEQGVGVPGGSPGSRHRQKAVVRHTIPEEETHR 172
L TV + + + D++G+SDPY V V G R ++K +
Sbjct: 293 LTLTVIKCRNLKAMDITGYSDPY--------VKVSLLCDGRRLKKK-------------K 331
Query: 173 TQVITQTLNPVWDETFILEF--EDITNASFHLDMWDLDTV 210
T + TLNPV++E I + E++ S + + D D V
Sbjct: 332 TTIKKNTLNPVYNEAIIFDIPPENMDQVSLLISVMDYDRV 371
>gi|21361472 neural precursor cell expressed, developmentally
down-regulated 4-like isoform 3 [Homo sapiens]
Length = 955
Score = 56.2 bits (134), Expect = 2e-07
Identities = 38/100 (38%), Positives = 54/100 (54%), Gaps = 5/100 (5%)
Query: 927 LRVELLSASSLLPLDSNGSSDPFVQLTLEPRHEFPELAARETQKHKKDLHPLFDETFEFL 986
LRV+++S L D G+SDP+V+L+L E ELA +T+ KK L+P ++E F F
Sbjct: 22 LRVKVVSGIDLAKKDIFGASDPYVKLSLYVADENRELALVQTKTIKKTLNPKWNEEFYFR 81
Query: 987 VPAEPCRKAGACLLLTVLDYDTLGADDLEGEAFLPLREVP 1026
V R LL V D + L DD G+ +PL +P
Sbjct: 82 VNPSNHR-----LLFEVFDENRLTRDDFLGQVDVPLSHLP 116
Score = 32.0 bits (71), Expect = 3.3
Identities = 42/160 (26%), Positives = 59/160 (36%), Gaps = 51/160 (31%)
Query: 113 LKATVKQAKGILGKDVSGFSDPYCLLGIEQGVGVPGGSPGSRHRQKAVVRHTIPEEETHR 172
L+ V + KD+ G SDPY L + +R+ A+V+
Sbjct: 22 LRVKVVSGIDLAKKDIFGASDPYVKLSLYVA---------DENRELALVQ---------- 62
Query: 173 TQVITQTLNPVWDETFILEFEDITNASFHLDMWDLDTVESVRQKLGELTDLHGLRRIFKE 232
T+ I +TLNP W+E F N S H + L E+ D + L R
Sbjct: 63 TKTIKKTLNPKWNEEFYFR----VNPSNH-------------RLLFEVFDENRLTR---- 101
Query: 233 ARKDKGQDDFLGNVVLRLQDLRCREDQWYPLEPRTETYPD 272
DDFLG V + L L + P R T+ D
Sbjct: 102 -------DDFLGQVDVPLSHLPTED----PTMERPYTFKD 130
>gi|222352090 neural precursor cell expressed, developmentally
down-regulated 4-like isoform 5 [Homo sapiens]
Length = 947
Score = 56.2 bits (134), Expect = 2e-07
Identities = 38/100 (38%), Positives = 54/100 (54%), Gaps = 5/100 (5%)
Query: 927 LRVELLSASSLLPLDSNGSSDPFVQLTLEPRHEFPELAARETQKHKKDLHPLFDETFEFL 986
LRV+++S L D G+SDP+V+L+L E ELA +T+ KK L+P ++E F F
Sbjct: 14 LRVKVVSGIDLAKKDIFGASDPYVKLSLYVADENRELALVQTKTIKKTLNPKWNEEFYFR 73
Query: 987 VPAEPCRKAGACLLLTVLDYDTLGADDLEGEAFLPLREVP 1026
V R LL V D + L DD G+ +PL +P
Sbjct: 74 VNPSNHR-----LLFEVFDENRLTRDDFLGQVDVPLSHLP 108
Score = 32.0 bits (71), Expect = 3.3
Identities = 42/160 (26%), Positives = 59/160 (36%), Gaps = 51/160 (31%)
Query: 113 LKATVKQAKGILGKDVSGFSDPYCLLGIEQGVGVPGGSPGSRHRQKAVVRHTIPEEETHR 172
L+ V + KD+ G SDPY L + +R+ A+V+
Sbjct: 14 LRVKVVSGIDLAKKDIFGASDPYVKLSLYVA---------DENRELALVQ---------- 54
Query: 173 TQVITQTLNPVWDETFILEFEDITNASFHLDMWDLDTVESVRQKLGELTDLHGLRRIFKE 232
T+ I +TLNP W+E F N S H + L E+ D + L R
Sbjct: 55 TKTIKKTLNPKWNEEFYFR----VNPSNH-------------RLLFEVFDENRLTR---- 93
Query: 233 ARKDKGQDDFLGNVVLRLQDLRCREDQWYPLEPRTETYPD 272
DDFLG V + L L + P R T+ D
Sbjct: 94 -------DDFLGQVDVPLSHLPTED----PTMERPYTFKD 122
>gi|222352088 neural precursor cell expressed, developmentally
down-regulated 4-like isoform 4 [Homo sapiens]
Length = 967
Score = 56.2 bits (134), Expect = 2e-07
Identities = 38/100 (38%), Positives = 54/100 (54%), Gaps = 5/100 (5%)
Query: 927 LRVELLSASSLLPLDSNGSSDPFVQLTLEPRHEFPELAARETQKHKKDLHPLFDETFEFL 986
LRV+++S L D G+SDP+V+L+L E ELA +T+ KK L+P ++E F F
Sbjct: 14 LRVKVVSGIDLAKKDIFGASDPYVKLSLYVADENRELALVQTKTIKKTLNPKWNEEFYFR 73
Query: 987 VPAEPCRKAGACLLLTVLDYDTLGADDLEGEAFLPLREVP 1026
V R LL V D + L DD G+ +PL +P
Sbjct: 74 VNPSNHR-----LLFEVFDENRLTRDDFLGQVDVPLSHLP 108
Score = 32.0 bits (71), Expect = 3.3
Identities = 42/160 (26%), Positives = 59/160 (36%), Gaps = 51/160 (31%)
Query: 113 LKATVKQAKGILGKDVSGFSDPYCLLGIEQGVGVPGGSPGSRHRQKAVVRHTIPEEETHR 172
L+ V + KD+ G SDPY L + +R+ A+V+
Sbjct: 14 LRVKVVSGIDLAKKDIFGASDPYVKLSLYVA---------DENRELALVQ---------- 54
Query: 173 TQVITQTLNPVWDETFILEFEDITNASFHLDMWDLDTVESVRQKLGELTDLHGLRRIFKE 232
T+ I +TLNP W+E F N S H + L E+ D + L R
Sbjct: 55 TKTIKKTLNPKWNEEFYFR----VNPSNH-------------RLLFEVFDENRLTR---- 93
Query: 233 ARKDKGQDDFLGNVVLRLQDLRCREDQWYPLEPRTETYPD 272
DDFLG V + L L + P R T+ D
Sbjct: 94 -------DDFLGQVDVPLSHLPTED----PTMERPYTFKD 122
>gi|222352086 neural precursor cell expressed, developmentally
down-regulated 4-like isoform 1 [Homo sapiens]
Length = 975
Score = 56.2 bits (134), Expect = 2e-07
Identities = 38/100 (38%), Positives = 54/100 (54%), Gaps = 5/100 (5%)
Query: 927 LRVELLSASSLLPLDSNGSSDPFVQLTLEPRHEFPELAARETQKHKKDLHPLFDETFEFL 986
LRV+++S L D G+SDP+V+L+L E ELA +T+ KK L+P ++E F F
Sbjct: 22 LRVKVVSGIDLAKKDIFGASDPYVKLSLYVADENRELALVQTKTIKKTLNPKWNEEFYFR 81
Query: 987 VPAEPCRKAGACLLLTVLDYDTLGADDLEGEAFLPLREVP 1026
V R LL V D + L DD G+ +PL +P
Sbjct: 82 VNPSNHR-----LLFEVFDENRLTRDDFLGQVDVPLSHLP 116
Score = 32.0 bits (71), Expect = 3.3
Identities = 42/160 (26%), Positives = 59/160 (36%), Gaps = 51/160 (31%)
Query: 113 LKATVKQAKGILGKDVSGFSDPYCLLGIEQGVGVPGGSPGSRHRQKAVVRHTIPEEETHR 172
L+ V + KD+ G SDPY L + +R+ A+V+
Sbjct: 22 LRVKVVSGIDLAKKDIFGASDPYVKLSLYVA---------DENRELALVQ---------- 62
Query: 173 TQVITQTLNPVWDETFILEFEDITNASFHLDMWDLDTVESVRQKLGELTDLHGLRRIFKE 232
T+ I +TLNP W+E F N S H + L E+ D + L R
Sbjct: 63 TKTIKKTLNPKWNEEFYFR----VNPSNH-------------RLLFEVFDENRLTR---- 101
Query: 233 ARKDKGQDDFLGNVVLRLQDLRCREDQWYPLEPRTETYPD 272
DDFLG V + L L + P R T+ D
Sbjct: 102 -------DDFLGQVDVPLSHLPTED----PTMERPYTFKD 130
>gi|39752671 synaptotagmin X [Homo sapiens]
Length = 523
Score = 56.2 bits (134), Expect = 2e-07
Identities = 40/119 (33%), Positives = 60/119 (50%), Gaps = 7/119 (5%)
Query: 912 GAVTVKASYRASEQKLRVELLSASSLLPLDSNGSSDPFVQLTLEPRHEFPELAARETQKH 971
G + Y + L V+++ A L D G+SDP+V++ L P + +T+ H
Sbjct: 233 GKLNFTLQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKMYLLPDRK----KKFQTRVH 288
Query: 972 KKDLHPLFDETFEFLVPAEPCRKAGACLLLTVLDYDTLGADDLEGEAFLP-LREVPGLS 1029
+K L+PLFDETF+F P + + L +V D+D D+ GE L L EV LS
Sbjct: 289 RKTLNPLFDETFQF--PVAYDQLSNRKLHFSVYDFDRFSRHDMIGEVILDNLFEVSDLS 345
Score = 54.7 bits (130), Expect = 5e-07
Identities = 40/146 (27%), Positives = 71/146 (48%), Gaps = 5/146 (3%)
Query: 904 AETTSEELGAVTVKASYRASEQKLRVELLSASSLLPLDSNGSSDPFVQLTLEPRHEFPEL 963
A T S +LG + Y + ++ + ++ +L +D GSSDP+V+++L E L
Sbjct: 357 ATTESIDLGEIMFSLCYLPTAGRMTLTVIKCRNLKAMDITGSSDPYVKVSL--MCEGRRL 414
Query: 964 AARETQKHKKDLHPLFDETFEFLVPAEPCRKAGACLLLTVLDYDTLGADDLEGEAFLPLR 1023
R+T K L+P+++E F +P E + L + V+DYD +G +++ G L
Sbjct: 415 KKRKTTTKKNTLNPVYNEAIIFDIPPENVDQVS--LSIAVMDYDRVGHNEVIGVCRTGL- 471
Query: 1024 EVPGLSGSEEPGEVPQTRLPLTYPAP 1049
+ GL + R P+T+ P
Sbjct: 472 DAEGLGRDHWNEMLAYHRKPITHWHP 497
Score = 39.3 bits (90), Expect = 0.020
Identities = 34/148 (22%), Positives = 64/148 (43%), Gaps = 34/148 (22%)
Query: 113 LKATVKQAKGILGKDVSGFSDPYCLLGIEQGVGVPGGSPGSRHRQKAVVRHTIPE-EETH 171
L + +A + KD +G SDPY V + +P+ ++
Sbjct: 248 LVVKIIKALDLPAKDFTGTSDPY------------------------VKMYLLPDRKKKF 283
Query: 172 RTQVITQTLNPVWDET--FILEFEDITNASFHLDMWDLDTV-------ESVRQKLGELTD 222
+T+V +TLNP++DET F + ++ ++N H ++D D E + L E++D
Sbjct: 284 QTRVHRKTLNPLFDETFQFPVAYDQLSNRKLHFSVYDFDRFSRHDMIGEVILDNLFEVSD 343
Query: 223 LHGLRRIFKEARKDKGQDDFLGNVVLRL 250
L ++K+ + LG ++ L
Sbjct: 344 LSREATVWKDIHCATTESIDLGEIMFSL 371
>gi|4506067 protein kinase C, alpha [Homo sapiens]
Length = 672
Score = 55.1 bits (131), Expect = 4e-07
Identities = 44/155 (28%), Positives = 80/155 (51%), Gaps = 26/155 (16%)
Query: 908 SEELGAVTVKASYRASEQKLRVELLSASSLLPLDSNGSSDPFVQLTL--EPRHEFPELAA 965
+E+ G + +KA +++KL V + A +L+P+D NG SDP+V+L L +P++E +
Sbjct: 156 TEKRGRIYLKAE--VADEKLHVTVRDAKNLIPMDPNGLSDPYVKLKLIPDPKNE----SK 209
Query: 966 RETQKHKKDLHPLFDETFEF-LVPAEPCRKAGACLLLTVLDYDTLGADDLEGEAFLPLRE 1024
++T+ + L+P ++E+F F L P++ R+ L + + D+D +D G + E
Sbjct: 210 QKTKTIRSTLNPQWNESFTFKLKPSDKDRR----LSVEIWDWDRTTRNDFMGSLSFGVSE 265
Query: 1025 VPGLSGS-------EEPGEVPQTRLPLTYPAPNGD 1052
+ + S +E GE P P GD
Sbjct: 266 LMKMPASGWYKLLNQEEGEY------YNVPIPEGD 294
Score = 40.8 bits (94), Expect = 0.007
Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 22/97 (22%)
Query: 113 LKATVKQAKGILGKDVSGFSDPYCLLGIEQGVGVPGGSPGSRHRQKAVVRHTIPEEETHR 172
L TV+ AK ++ D +G SDPY L + +P P + +QK
Sbjct: 173 LHVTVRDAKNLIPMDPNGLSDPYVKLKL-----IP--DPKNESKQK-------------- 211
Query: 173 TQVITQTLNPVWDETFILEFE-DITNASFHLDMWDLD 208
T+ I TLNP W+E+F + + + +++WD D
Sbjct: 212 TKTIRSTLNPQWNESFTFKLKPSDKDRRLSVEIWDWD 248
>gi|47078261 double C2-like domains, alpha [Homo sapiens]
Length = 400
Score = 54.3 bits (129), Expect = 6e-07
Identities = 38/115 (33%), Positives = 58/115 (50%), Gaps = 4/115 (3%)
Query: 902 QQAETTSEELGAVTVKASYRASEQKLRVELLSASSLLPLDSNGSSDPFVQLTLEPRHEFP 961
+Q + EE G + + SY + + L V +L + L +D NG SDP+V+ L P +
Sbjct: 243 EQGQGLLEERGRILLSLSYSSRRRGLLVGILRCAHLAAMDVNGYSDPYVKTYLRP--DVD 300
Query: 962 ELAARETQKHKKDLHPLFDETFEFLVPAEPCRKAGACLLLTVLDYDTLGADDLEG 1016
+ + +T KK L+P F+E EF E A L +TV DYD ++D G
Sbjct: 301 KKSKHKTCVKKKTLNPEFNE--EFFYEIELSTLATKTLEVTVWDYDIGKSNDFIG 353
Score = 43.5 bits (101), Expect = 0.001
Identities = 34/117 (29%), Positives = 56/117 (47%), Gaps = 7/117 (5%)
Query: 911 LGAVTVKASYRASEQKLRVELLSASSLLPLDSNGSSDPFVQLTLEPRHEFPELAARETQK 970
LG + Y + L +L A L P+D NG +DP+V+L L P +TQ+
Sbjct: 90 LGTLEFDLLYDRASCTLHCSILRAKGLKPMDFNGLADPYVKLHLLPGACKANKLKTKTQR 149
Query: 971 HKKDLHPLFDE--TFEFLVPAEPCRKAGACLLLTVLDYDTLGADDLEGEAFLPLREV 1025
+ L+P+++E T+ + + K L + V D D L ++ GE +PLR +
Sbjct: 150 N--TLNPVWNEDLTYSGITDDDITHKV---LRIAVCDEDKLSHNEFIGEIRVPLRRL 201
Score = 38.5 bits (88), Expect = 0.035
Identities = 27/88 (30%), Positives = 41/88 (46%), Gaps = 23/88 (26%)
Query: 127 DVSGFSDPYCLLGIEQGVGVPGGSPGSRHRQKAVVRHTIPEEETHRTQVITQTLNPVWDE 186
DV+G+SDPY K +R + ++ H+T V +TLNP ++E
Sbjct: 282 DVNGYSDPYV---------------------KTYLRPDVDKKSKHKTCVKKKTLNPEFNE 320
Query: 187 TFILEFEDITNASFHLD--MWDLDTVES 212
F E E T A+ L+ +WD D +S
Sbjct: 321 EFFYEIELSTLATKTLEVTVWDYDIGKS 348
Score = 34.3 bits (77), Expect = 0.66
Identities = 30/111 (27%), Positives = 51/111 (45%), Gaps = 25/111 (22%)
Query: 113 LKATVKQAKGILGKDVSGFSDPYCLLGIEQGVGVPGGSPGSRHRQKAVVRHTIPEEETHR 172
L ++ +AKG+ D +G +DPY L + +PG ++ + K T R
Sbjct: 106 LHCSILRAKGLKPMDFNGLADPYVKLHL-----LPGACKANKLKTK-----------TQR 149
Query: 173 TQVITQTLNPVWDETFI---LEFEDITNASFHLDMWDLDTVESVRQKLGEL 220
TLNPVW+E + +DIT+ + + D D + S + +GE+
Sbjct: 150 -----NTLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKL-SHNEFIGEI 194
>gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]
Length = 694
Score = 54.3 bits (129), Expect = 6e-07
Identities = 38/108 (35%), Positives = 56/108 (51%), Gaps = 4/108 (3%)
Query: 909 EELGAVTVKASYRASEQKLRVELLSASSLLPLDSNGSSDPFVQLTLEPRHEFPELAARET 968
EE G + V Y + L V ++ L +D+NG SDPFV+L L+P + + A +T
Sbjct: 549 EERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKP--DMGKKAKHKT 606
Query: 969 QKHKKDLHPLFDETFEFLVPAEPCRKAGACLLLTVLDYDTLGADDLEG 1016
Q KK L+P F+E EF + A L ++V DYD ++D G
Sbjct: 607 QIKKKTLNPEFNE--EFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIG 652
Score = 46.6 bits (109), Expect = 1e-04
Identities = 32/117 (27%), Positives = 58/117 (49%), Gaps = 7/117 (5%)
Query: 911 LGAVTVKASYRASEQKLRVELLSASSLLPLDSNGSSDPFVQLTLEPRHEFPELAARETQK 970
LGA+ Y L+ ++ A L P+DSNG +DP+V+L L P +T +
Sbjct: 393 LGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLR 452
Query: 971 HKKDLHPLFDETFEF--LVPAEPCRKAGACLLLTVLDYDTLGADDLEGEAFLPLREV 1025
+ + +P+++ET + + + RK L ++V D D G ++ GE L+++
Sbjct: 453 NTR--NPIWNETLVYHGITDEDMQRKT---LRISVCDEDKFGHNEFIGETRFSLKKL 504
Score = 40.0 bits (92), Expect = 0.012
Identities = 30/130 (23%), Positives = 56/130 (43%), Gaps = 32/130 (24%)
Query: 94 EEHQQTLQRVRELEKPIFCLKATVKQAKGILG---------KDVSGFSDPYCLLGIEQGV 144
EE + + + E K + L + +Q I+G D +G+SDP+ L ++ +
Sbjct: 539 EEQVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDM 598
Query: 145 GVPGGSPGSRHRQKAVVRHTIPEEETHRTQVITQTLNPVWDETFI--LEFEDITNASFHL 202
G ++ H+TQ+ +TLNP ++E F ++ D+ S +
Sbjct: 599 G---------------------KKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDI 637
Query: 203 DMWDLDTVES 212
+WD D +S
Sbjct: 638 SVWDYDIGKS 647
Score = 39.7 bits (91), Expect = 0.016
Identities = 26/99 (26%), Positives = 46/99 (46%), Gaps = 24/99 (24%)
Query: 113 LKATVKQAKGILGKDVSGFSDPYCLLGIEQGVGVPGGSPGSRHRQKAVVRHTIPEEETHR 172
L+ T+ +AKG+ D +G +DPY L + +PG S ++ R
Sbjct: 409 LQCTIIKAKGLKPMDSNGLADPYVKLHL-----LPGASKSNK----------------LR 447
Query: 173 TQVITQTLNPVWDETFI---LEFEDITNASFHLDMWDLD 208
T+ + T NP+W+ET + + ED+ + + + D D
Sbjct: 448 TKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDED 486
>gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]
Length = 690
Score = 54.3 bits (129), Expect = 6e-07
Identities = 38/108 (35%), Positives = 56/108 (51%), Gaps = 4/108 (3%)
Query: 909 EELGAVTVKASYRASEQKLRVELLSASSLLPLDSNGSSDPFVQLTLEPRHEFPELAARET 968
EE G + V Y + L V ++ L +D+NG SDPFV+L L+P + + A +T
Sbjct: 545 EERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKP--DMGKKAKHKT 602
Query: 969 QKHKKDLHPLFDETFEFLVPAEPCRKAGACLLLTVLDYDTLGADDLEG 1016
Q KK L+P F+E EF + A L ++V DYD ++D G
Sbjct: 603 QIKKKTLNPEFNE--EFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIG 648
Score = 46.6 bits (109), Expect = 1e-04
Identities = 32/117 (27%), Positives = 58/117 (49%), Gaps = 7/117 (5%)
Query: 911 LGAVTVKASYRASEQKLRVELLSASSLLPLDSNGSSDPFVQLTLEPRHEFPELAARETQK 970
LGA+ Y L+ ++ A L P+DSNG +DP+V+L L P +T +
Sbjct: 389 LGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLR 448
Query: 971 HKKDLHPLFDETFEF--LVPAEPCRKAGACLLLTVLDYDTLGADDLEGEAFLPLREV 1025
+ + +P+++ET + + + RK L ++V D D G ++ GE L+++
Sbjct: 449 NTR--NPIWNETLVYHGITDEDMQRKT---LRISVCDEDKFGHNEFIGETRFSLKKL 500
Score = 40.0 bits (92), Expect = 0.012
Identities = 30/130 (23%), Positives = 56/130 (43%), Gaps = 32/130 (24%)
Query: 94 EEHQQTLQRVRELEKPIFCLKATVKQAKGILG---------KDVSGFSDPYCLLGIEQGV 144
EE + + + E K + L + +Q I+G D +G+SDP+ L ++ +
Sbjct: 535 EEQVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDM 594
Query: 145 GVPGGSPGSRHRQKAVVRHTIPEEETHRTQVITQTLNPVWDETFI--LEFEDITNASFHL 202
G ++ H+TQ+ +TLNP ++E F ++ D+ S +
Sbjct: 595 G---------------------KKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDI 633
Query: 203 DMWDLDTVES 212
+WD D +S
Sbjct: 634 SVWDYDIGKS 643
Score = 39.7 bits (91), Expect = 0.016
Identities = 26/99 (26%), Positives = 46/99 (46%), Gaps = 24/99 (24%)
Query: 113 LKATVKQAKGILGKDVSGFSDPYCLLGIEQGVGVPGGSPGSRHRQKAVVRHTIPEEETHR 172
L+ T+ +AKG+ D +G +DPY L + +PG S ++ R
Sbjct: 405 LQCTIIKAKGLKPMDSNGLADPYVKLHL-----LPGASKSNK----------------LR 443
Query: 173 TQVITQTLNPVWDETFI---LEFEDITNASFHLDMWDLD 208
T+ + T NP+W+ET + + ED+ + + + D D
Sbjct: 444 TKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDED 482
>gi|6005997 double C2-like domains, beta [Homo sapiens]
Length = 412
Score = 53.9 bits (128), Expect = 8e-07
Identities = 35/121 (28%), Positives = 61/121 (50%), Gaps = 4/121 (3%)
Query: 900 IQQQAETTSEELGAVTVKASYRASEQKLRVELLSASSLLPLDSNGSSDPFVQLTLEPRHE 959
+ + + + EE G + + Y + +Q L V ++ + L +D+NG SDP+V+ L P +
Sbjct: 256 VDKTEDKSLEERGRILISLKYSSQKQGLLVGIVRCAHLAAMDANGYSDPYVKTYLRP--D 313
Query: 960 FPELAARETQKHKKDLHPLFDETFEFLVPAEPCRKAGACLLLTVLDYDTLGADDLEGEAF 1019
+ + +T KK L+P F+E F + + K L +TV DYD ++D G
Sbjct: 314 VDKKSKHKTAVKKKTLNPEFNEEFCYEIKHGDLAKKS--LEVTVWDYDIGKSNDFIGGVV 371
Query: 1020 L 1020
L
Sbjct: 372 L 372
Score = 42.7 bits (99), Expect = 0.002
Identities = 31/117 (26%), Positives = 54/117 (46%), Gaps = 7/117 (5%)
Query: 911 LGAVTVKASYRASEQKLRVELLSASSLLPLDSNGSSDPFVQLTLEPRHEFPELAARETQK 970
LG + Y L + A L P+D NG +DP+V+L L P + T+
Sbjct: 127 LGTLDFSLLYDQENNALHCTITKAKGLKPMDHNGLADPYVKLHLLPGAS--KANKLRTKT 184
Query: 971 HKKDLHPLFDETFEF--LVPAEPCRKAGACLLLTVLDYDTLGADDLEGEAFLPLREV 1025
+ L+P ++ET + + + RK L ++V D D ++ GE +PL+++
Sbjct: 185 LRNTLNPTWNETLTYYGITDEDMIRKT---LRISVCDEDKFRHNEFIGETRVPLKKL 238
Score = 39.3 bits (90), Expect = 0.020
Identities = 24/88 (27%), Positives = 39/88 (44%), Gaps = 23/88 (26%)
Query: 127 DVSGFSDPYCLLGIEQGVGVPGGSPGSRHRQKAVVRHTIPEEETHRTQVITQTLNPVWDE 186
D +G+SDPY K +R + ++ H+T V +TLNP ++E
Sbjct: 297 DANGYSDPYV---------------------KTYLRPDVDKKSKHKTAVKKKTLNPEFNE 335
Query: 187 TFILEFE--DITNASFHLDMWDLDTVES 212
F E + D+ S + +WD D +S
Sbjct: 336 EFCYEIKHGDLAKKSLEVTVWDYDIGKS 363
Score = 38.9 bits (89), Expect = 0.027
Identities = 27/99 (27%), Positives = 45/99 (45%), Gaps = 24/99 (24%)
Query: 113 LKATVKQAKGILGKDVSGFSDPYCLLGIEQGVGVPGGSPGSRHRQKAVVRHTIPEEETHR 172
L T+ +AKG+ D +G +DPY L + +PG S ++ R
Sbjct: 143 LHCTITKAKGLKPMDHNGLADPYVKLHL-----LPGASKANK----------------LR 181
Query: 173 TQVITQTLNPVWDET---FILEFEDITNASFHLDMWDLD 208
T+ + TLNP W+ET + + ED+ + + + D D
Sbjct: 182 TKTLRNTLNPTWNETLTYYGITDEDMIRKTLRISVCDED 220
>gi|28376627 synaptotagmin IX [Homo sapiens]
Length = 491
Score = 53.5 bits (127), Expect = 1e-06
Identities = 38/125 (30%), Positives = 61/125 (48%), Gaps = 10/125 (8%)
Query: 906 TTSEELGAVTVKASYRASEQKLRVELLSASSLLPLDSNGSSDPFVQLTLEPRHEFPELAA 965
+ S+ G + Y ++L V++ A +L D +G+SDP+V++ L P +
Sbjct: 216 SNSKACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPDRK----TK 271
Query: 966 RETQKHKKDLHPLFDETFEFLVPAEPCRKAGACLLLTVLDYDTLGADDLEGEA----FLP 1021
+T+ H+K L+P+FDE F F VP L +V D+D DL G+ FL
Sbjct: 272 HQTKVHRKTLNPVFDEVFLFPVPYNDLE--ARKLHFSVYDFDRFSRHDLIGQVVVDHFLD 329
Query: 1022 LREVP 1026
L + P
Sbjct: 330 LADFP 334
Score = 50.8 bits (120), Expect = 7e-06
Identities = 30/107 (28%), Positives = 58/107 (54%), Gaps = 4/107 (3%)
Query: 910 ELGAVTVKASYRASEQKLRVELLSASSLLPLDSNGSSDPFVQLTLEPRHEFPELAARETQ 969
+LG + Y + +L + ++ A +L +D G+SDP+V+++L + L R+T
Sbjct: 352 DLGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSL--MCDGRRLKKRKTS 409
Query: 970 KHKKDLHPLFDETFEFLVPAEPCRKAGACLLLTVLDYDTLGADDLEG 1016
+ L+P+++E F VP E + L + V+DYD +G +++ G
Sbjct: 410 TKRNTLNPVYNEAIVFDVPPENIDQIH--LSIAVMDYDRVGHNEIIG 454
Score = 41.2 bits (95), Expect = 0.005
Identities = 26/95 (27%), Positives = 44/95 (46%), Gaps = 27/95 (28%)
Query: 117 VKQAKGILGKDVSGFSDPYCLLGIEQGVGVPGGSPGSRHRQKAVVRHTIPEEET-HRTQV 175
+ +A + KD SG SDPY + + +P+ +T H+T+V
Sbjct: 241 IHKAVNLPAKDFSGTSDPYVKI------------------------YLLPDRKTKHQTKV 276
Query: 176 ITQTLNPVWDETFI--LEFEDITNASFHLDMWDLD 208
+TLNPV+DE F+ + + D+ H ++D D
Sbjct: 277 HRKTLNPVFDEVFLFPVPYNDLEARKLHFSVYDFD 311
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.134 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,011,124
Number of Sequences: 37866
Number of extensions: 1940965
Number of successful extensions: 6550
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 48
Number of HSP's successfully gapped in prelim test: 108
Number of HSP's that attempted gapping in prelim test: 5991
Number of HSP's gapped (non-prelim): 525
length of query: 1090
length of database: 18,247,518
effective HSP length: 113
effective length of query: 977
effective length of database: 13,968,660
effective search space: 13647380820
effective search space used: 13647380820
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.