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Search of human proteins with 46049119
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|46049119 myosin binding protein C, slow type isoform 3 [Homo
sapiens]
(1141 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|46049119 myosin binding protein C, slow type isoform 3 [Homo ... 2319 0.0
gi|46049110 myosin binding protein C, slow type isoform 4 [Homo ... 2271 0.0
gi|46049125 myosin binding protein C, slow type isoform 2 [Homo ... 2258 0.0
gi|45976288 myosin binding protein C, slow type isoform 1 [Homo ... 2255 0.0
gi|133908641 myosin binding protein C, fast type [Homo sapiens] 1158 0.0
gi|148596957 myosin binding protein C, cardiac [Homo sapiens] 1139 0.0
gi|55956914 myosin binding protein H [Homo sapiens] 448 e-125
gi|194018539 myosin binding protein H-like [Homo sapiens] 375 e-103
gi|253970427 immunoglobulin superfamily, member 22 [Homo sapiens] 291 3e-78
gi|110349719 titin isoform N2-A [Homo sapiens] 288 2e-77
gi|110349717 titin isoform novex-2 [Homo sapiens] 288 2e-77
gi|110349713 titin isoform novex-1 [Homo sapiens] 288 2e-77
gi|110349715 titin isoform N2-B [Homo sapiens] 288 2e-77
gi|148839296 immunoglobulin-like and fibronectin type III domain... 239 8e-63
gi|110349721 titin isoform novex-3 [Homo sapiens] 139 2e-32
gi|58331253 obscurin, cytoskeletal calmodulin and titin-interact... 129 2e-29
gi|148833506 obscurin, cytoskeletal calmodulin and titin-interac... 129 2e-29
gi|156104903 myomesin 2 [Homo sapiens] 125 2e-28
gi|140560917 myomesin 1 isoform b [Homo sapiens] 122 1e-27
gi|118572606 hemicentin 1 [Homo sapiens] 119 2e-26
gi|144226847 obscurin-like 1 [Homo sapiens] 116 1e-25
gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42... 111 3e-24
gi|21359935 Down syndrome cell adhesion molecule like 1 [Homo sa... 111 4e-24
gi|157785645 SPEG complex locus [Homo sapiens] 110 8e-24
gi|19743806 roundabout 1 isoform b [Homo sapiens] 105 3e-22
gi|4506569 roundabout 1 isoform a [Homo sapiens] 105 3e-22
gi|140560919 myomesin 1 isoform a [Homo sapiens] 105 3e-22
gi|224994173 roundabout 1 isoform d [Homo sapiens] 102 2e-21
gi|224994171 roundabout 1 isoform c [Homo sapiens] 102 2e-21
gi|239748173 PREDICTED: similar to roundabout 1 isoform 1 [Homo ... 102 2e-21
>gi|46049119 myosin binding protein C, slow type isoform 3 [Homo
sapiens]
Length = 1141
Score = 2319 bits (6009), Expect = 0.0
Identities = 1141/1141 (100%), Positives = 1141/1141 (100%)
Query: 1 MPEPTKKEENEVPAPAPPPEEPSKEKEAGTTPAKDWTLVETPPGEEQAKQNANSQLSILF 60
MPEPTKKEENEVPAPAPPPEEPSKEKEAGTTPAKDWTLVETPPGEEQAKQNANSQLSILF
Sbjct: 1 MPEPTKKEENEVPAPAPPPEEPSKEKEAGTTPAKDWTLVETPPGEEQAKQNANSQLSILF 60
Query: 61 IEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAGKHLQLKETFERHS 120
IEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAGKHLQLKETFERHS
Sbjct: 61 IEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAGKHLQLKETFERHS 120
Query: 121 RVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSGE 180
RVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSGE
Sbjct: 121 RVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSGE 180
Query: 181 GQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKR 240
GQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKR
Sbjct: 181 GQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKR 240
Query: 241 LKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIF 300
LKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIF
Sbjct: 241 LKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIF 300
Query: 301 EHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVE 360
EHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVE
Sbjct: 301 EHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVE 360
Query: 361 LECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGG 420
LECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGG
Sbjct: 361 LECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGG 420
Query: 421 QSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVV 480
QSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVV
Sbjct: 421 QSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVV 480
Query: 481 HKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAG 540
HKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAG
Sbjct: 481 HKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAG 540
Query: 541 NKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHIN 600
NKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHIN
Sbjct: 541 NKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHIN 600
Query: 601 LKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKK 660
LKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKK
Sbjct: 601 LKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKK 660
Query: 661 KQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSP 720
KQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSP
Sbjct: 661 KQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSP 720
Query: 721 PTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAE 780
PTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAE
Sbjct: 721 PTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAE 780
Query: 781 DWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIR 840
DWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIR
Sbjct: 781 DWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIR 840
Query: 841 IPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRK 900
IPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRK
Sbjct: 841 IPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRK 900
Query: 901 AERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGN 960
AERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGN
Sbjct: 901 AERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGN 960
Query: 961 AAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMT 1020
AAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMT
Sbjct: 961 AAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMT 1020
Query: 1021 KESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITW 1080
KESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITW
Sbjct: 1021 KESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITW 1080
Query: 1081 MKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVIA 1140
MKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVIA
Sbjct: 1081 MKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVIA 1140
Query: 1141 Q 1141
Q
Sbjct: 1141 Q 1141
>gi|46049110 myosin binding protein C, slow type isoform 4 [Homo
sapiens]
Length = 1123
Score = 2271 bits (5886), Expect = 0.0
Identities = 1122/1141 (98%), Positives = 1123/1141 (98%), Gaps = 18/1141 (1%)
Query: 1 MPEPTKKEENEVPAPAPPPEEPSKEKEAGTTPAKDWTLVETPPGEEQAKQNANSQLSILF 60
MPEPTKKEENEVPAPAPPPEEPSKEKEAGTTPAKDWTLVETPPGEEQAKQNANSQLSILF
Sbjct: 1 MPEPTKKEENEVPAPAPPPEEPSKEKEAGTTPAKDWTLVETPPGEEQAKQNANSQLSILF 60
Query: 61 IEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAGKHLQLKETFERHS 120
IEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAGKHLQLKETFERHS
Sbjct: 61 IEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAGKHLQLKETFERHS 120
Query: 121 RVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSGE 180
RVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSGE
Sbjct: 121 RVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSGE 180
Query: 181 GQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKR 240
GQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKR
Sbjct: 181 GQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKR 240
Query: 241 LKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIF 300
LKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIF
Sbjct: 241 LKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIF 300
Query: 301 EHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVE 360
EHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVE
Sbjct: 301 EHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVE 360
Query: 361 LECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGG 420
LECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGG
Sbjct: 361 LECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGG 420
Query: 421 QSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVV 480
QSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVV
Sbjct: 421 QSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVV 480
Query: 481 HKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAG 540
HKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAG
Sbjct: 481 HKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAG 540
Query: 541 NKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHIN 600
NKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHIN
Sbjct: 541 NKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHIN 600
Query: 601 LKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKK 660
LKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKK
Sbjct: 601 LKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKK 660
Query: 661 KQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSP 720
KQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSP
Sbjct: 661 KQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSP 720
Query: 721 PTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAE 780
PTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEG+ E
Sbjct: 721 PTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGT------------------E 762
Query: 781 DWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIR 840
DWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIR
Sbjct: 763 DWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIR 822
Query: 841 IPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRK 900
IPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRK
Sbjct: 823 IPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRK 882
Query: 901 AERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGN 960
AERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGN
Sbjct: 883 AERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGN 942
Query: 961 AAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMT 1020
AAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMT
Sbjct: 943 AAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMT 1002
Query: 1021 KESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITW 1080
KESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITW
Sbjct: 1003 KESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITW 1062
Query: 1081 MKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVIA 1140
MKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVIA
Sbjct: 1063 MKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVIA 1122
Query: 1141 Q 1141
Q
Sbjct: 1123 Q 1123
>gi|46049125 myosin binding protein C, slow type isoform 2 [Homo
sapiens]
Length = 1148
Score = 2258 bits (5850), Expect = 0.0
Identities = 1122/1166 (96%), Positives = 1123/1166 (96%), Gaps = 43/1166 (3%)
Query: 1 MPEPTKKEENEVPAPAPPPEEPSKEKEAGTTPAKD------------------------- 35
MPEPTKKEENEVPAPAPPPEEPSKEKEAGTTPAKD
Sbjct: 1 MPEPTKKEENEVPAPAPPPEEPSKEKEAGTTPAKDEEEVSPPSALPPGLGSRALERKDSD 60
Query: 36 WTLVETPPGEEQAKQNANSQLSILFIEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWF 95
WTLVETPPGEEQAKQNANSQLSILFIEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWF
Sbjct: 61 WTLVETPPGEEQAKQNANSQLSILFIEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWF 120
Query: 96 KGKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSF 155
KGKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSF
Sbjct: 121 KGKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSF 180
Query: 156 DLEVHESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLK 215
DLEVHESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLK
Sbjct: 181 DLEVHESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLK 240
Query: 216 NAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVE 275
NAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVE
Sbjct: 241 NAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVE 300
Query: 276 LADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTEL 335
LADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTEL
Sbjct: 301 LADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTEL 360
Query: 336 FVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEG 395
FVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEG
Sbjct: 361 FVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEG 420
Query: 396 KKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCE 455
KKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCE
Sbjct: 421 KKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCE 480
Query: 456 ISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAK 515
ISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAK
Sbjct: 481 ISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAK 540
Query: 516 VHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRT 575
VHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRT
Sbjct: 541 VHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRT 600
Query: 576 ESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDW 635
ESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDW
Sbjct: 601 ESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDW 660
Query: 636 CIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIF 695
CIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIF
Sbjct: 661 CIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIF 720
Query: 696 AVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLE 755
AVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLE
Sbjct: 721 AVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLE 780
Query: 756 YCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNA 815
YCFEG+ EDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNA
Sbjct: 781 YCFEGT------------------EDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNA 822
Query: 816 AGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKK 875
AGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKK
Sbjct: 823 AGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKK 882
Query: 876 DGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPP 935
DGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPP
Sbjct: 883 DGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPP 942
Query: 936 QIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITEL 995
QIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITEL
Sbjct: 943 QIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITEL 1002
Query: 996 VIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVN 1055
VIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVN
Sbjct: 1003 VIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVN 1062
Query: 1056 TYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGG 1115
TYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGG
Sbjct: 1063 TYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGG 1122
Query: 1116 TYCCKAVNDLGTVEIECKLEVKVIAQ 1141
TYCCKAVNDLGTVEIECKLEVKVIAQ
Sbjct: 1123 TYCCKAVNDLGTVEIECKLEVKVIAQ 1148
>gi|45976288 myosin binding protein C, slow type isoform 1 [Homo
sapiens]
Length = 1171
Score = 2255 bits (5844), Expect = 0.0
Identities = 1121/1166 (96%), Positives = 1122/1166 (96%), Gaps = 43/1166 (3%)
Query: 1 MPEPTKKEENEVPAPAPPPEEPSKEKEAGTTPAKD------------------------- 35
MPEPTKKEENEVPAPAPPPEEPSKEKEAGTTPAKD
Sbjct: 1 MPEPTKKEENEVPAPAPPPEEPSKEKEAGTTPAKDEEEVSPPSALPPGLGSRALERKDSD 60
Query: 36 WTLVETPPGEEQAKQNANSQLSILFIEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWF 95
WTLVETPPGEEQAKQNANSQLSILFIEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWF
Sbjct: 61 WTLVETPPGEEQAKQNANSQLSILFIEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWF 120
Query: 96 KGKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSF 155
KGKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSF
Sbjct: 121 KGKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSF 180
Query: 156 DLEVHESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLK 215
DLEVHESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLK
Sbjct: 181 DLEVHESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLK 240
Query: 216 NAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVE 275
NAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVE
Sbjct: 241 NAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVE 300
Query: 276 LADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTEL 335
LADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTEL
Sbjct: 301 LADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTEL 360
Query: 336 FVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEG 395
FVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEG
Sbjct: 361 FVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEG 420
Query: 396 KKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCE 455
KKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCE
Sbjct: 421 KKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCE 480
Query: 456 ISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAK 515
ISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAK
Sbjct: 481 ISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAK 540
Query: 516 VHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRT 575
VHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRT
Sbjct: 541 VHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRT 600
Query: 576 ESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDW 635
ESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDW
Sbjct: 601 ESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDW 660
Query: 636 CIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIF 695
CIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIF
Sbjct: 661 CIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIF 720
Query: 696 AVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLE 755
AVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLE
Sbjct: 721 AVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLE 780
Query: 756 YCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNA 815
YCFEG+ EDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNA
Sbjct: 781 YCFEGT------------------EDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNA 822
Query: 816 AGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKK 875
AGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKK
Sbjct: 823 AGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKK 882
Query: 876 DGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPP 935
DGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPP
Sbjct: 883 DGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPP 942
Query: 936 QIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITEL 995
QIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITEL
Sbjct: 943 QIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITEL 1002
Query: 996 VIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVN 1055
VIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVN
Sbjct: 1003 VIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVN 1062
Query: 1056 TYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGG 1115
TYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGG
Sbjct: 1063 TYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGG 1122
Query: 1116 TYCCKAVNDLGTVEIECKLEVKVIAQ 1141
TYCCKAVNDLGTVEIECKLEVKVI Q
Sbjct: 1123 TYCCKAVNDLGTVEIECKLEVKVIYQ 1148
>gi|133908641 myosin binding protein C, fast type [Homo sapiens]
Length = 1141
Score = 1158 bits (2996), Expect = 0.0
Identities = 572/1153 (49%), Positives = 782/1153 (67%), Gaps = 62/1153 (5%)
Query: 13 PAPAPPPEEPSKE-KEAGTTPAKDWTLVETPPGEEQAKQNANSQLSILFIEKPQGGTVKV 71
P APP E P++ KEA P +D ++P EE +F++KP +V+
Sbjct: 22 PKEAPPKEAPAEAPKEA---PPED----QSPTAEEPTG---------VFLKKPDSVSVET 65
Query: 72 GEDITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIK 131
G+D +AKV ++L KPTIKWFKGKW++L SK+G KE+ S VYT E+ I K
Sbjct: 66 GKDAVVVAKVNGKELPDKPTIKWFKGKWLELGSKSGARFSFKESHNSASNVYTVELHIGK 125
Query: 132 AKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSGEGQED-AGELDF 190
G YR EV KD DSC F+++V + S FKR+ E + D AGELDF
Sbjct: 126 VVLGDRGYYRLEVKAKDTCDSCGFNIDVEAPRQDASGQSLES-FKRTSEKKSDTAGELDF 184
Query: 191 SGLLKRREVKQQEEEPQV----------DVWELLKNAKPSEYEKIAFQYGITDLRGMLKR 240
SGLLK+REV ++E++ + ++WELLK AK SEYEKIAFQYGITDLRGMLKR
Sbjct: 185 SGLLKKREVVEEEKKKKKKDDDDLGIPPEIWELLKGAKKSEYEKIAFQYGITDLRGMLKR 244
Query: 241 LKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIF 300
LK+ + E KKSAAF K LDPAYQVD+G +++ +VE++DP L +KW+KNGQEI+PS+KY+F
Sbjct: 245 LKKAKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVF 304
Query: 301 EHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVE 360
E+ G +RIL IN C + DD+ Y V DEKC TELFV+EPP+++ LED + G+RVE
Sbjct: 305 ENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVE 364
Query: 361 LECEVSEDDANVKWFKNGEEIIPGP--KSRYRIRVEGKKHILIIEGATKADAAEYSVMTT 418
+ EVSE+ A V W K+G E+ K+RYR + +GK+HILI + D Y V+T
Sbjct: 365 MAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITN 424
Query: 419 GGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRL 477
GGQ A+L V+ K L++L + D TV ++ KCE+S E + GKW KNG+ V+ S R+
Sbjct: 425 GGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRI 484
Query: 478 KVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVID----------PPKIILD 527
+ H GR HKLVI + EDEGDY F PD Y ++L AK++ ++ PPKI LD
Sbjct: 485 TISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLD 544
Query: 528 --GLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLV 585
G ++N + V+AGNKLRL++ I+GEPPP A W +GD+ GR R E D S+ V
Sbjct: 545 CSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFV 604
Query: 586 IDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAY 645
I+ A+R+D G Y I + N GE ASI ++VVD PDPP A +T VG+DW I+ WEPP Y
Sbjct: 605 IESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMY 664
Query: 646 DGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKP 705
DGG P+ GY +ERKKK S RWM+LNF++ ETT+E KMIEG+ YE+R+FAVNAIG+S+P
Sbjct: 665 DGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQP 724
Query: 706 SMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAK 765
SM ++PF+P+A TS P L V+ VTDTT T++WRPP+ IGA G+DGY++EYC EGS
Sbjct: 725 SMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGS---- 780
Query: 766 QSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYS 825
E+W+ AN + +++ FT+ LPT A+I RV VN AG SEP +
Sbjct: 781 --------------EEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLA 826
Query: 826 QPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQI 885
QP+ ++EI EPPKIR+PRHL+QTYIR+VGE +NLV+PFQGKPRP++ W K GA +D +++
Sbjct: 827 QPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRV 886
Query: 886 NIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWG 945
++R S+ DT+ F+R+A RS SG+Y+L V+++ +TA+I I+++++ GPP V +++VWG
Sbjct: 887 HVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWG 946
Query: 946 ENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRV 1005
N + W PKDDGN+ I GY +QKADKK+MEWF V E TS T+++L++GNEYYFRV
Sbjct: 947 TNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRV 1006
Query: 1006 FSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNAT 1065
++EN+CGLS+ ++K +A I + G +K Y++ DF AP F PL++ +AGY+A
Sbjct: 1007 YTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAA 1066
Query: 1066 LNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDL 1125
LNC+VRG+PKPK+ WMKNK+ I +DP++ + + QGV TL IR+PSP+D GTY C+AVN+L
Sbjct: 1067 LNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNEL 1126
Query: 1126 GTVEIECKLEVKV 1138
G ECKLEV+V
Sbjct: 1127 GEALAECKLEVRV 1139
>gi|148596957 myosin binding protein C, cardiac [Homo sapiens]
Length = 1274
Score = 1139 bits (2946), Expect = 0.0
Identities = 583/1204 (48%), Positives = 776/1204 (64%), Gaps = 95/1204 (7%)
Query: 3 EPTKKEENEVPAPAP------PPEEPSKEKEAGTTPAKDWTLVETPPGEEQAKQN----- 51
E K E PAPAP P E P+ E G + +P G A N
Sbjct: 96 EAEKAEPMLAPAPAPAEATGAPGEAPAPAAELGES-------APSPKGSSSAALNGPTPG 148
Query: 52 ANSQLSILFIEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAGKHLQ 111
A LF+ +PQ G V VG ITF A+V LL+ P +KWFKGKW+DL+SK G+HLQ
Sbjct: 149 APDDPIGLFVMRPQDGEVTVGGSITFSARVAGASLLKPPVVKWFKGKWVDLSSKVGQHLQ 208
Query: 112 LKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDI 171
L ++++R S+VY FE+ I A+ F G+YRCEV+ KDKFD +F+L VHE+ GT ++D+
Sbjct: 209 LHDSYDRASKVYLFELHITDAQPAFTGSYRCEVSTKDKFDCSNFNLTVHEAMGTG-DLDL 267
Query: 172 RSAFKRSG---------EGQEDAGELDFSGLLKRREV------KQQEEEPQVDVWELLKN 216
SAF+R+ + ED G LDFS LLK+R+ + E + DVWE+L+
Sbjct: 268 LSAFRRTSLAGGGRRISDSHEDTGILDFSSLLKKRDSFRTPRDSKLEAPAEEDVWEILRQ 327
Query: 217 AKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVEL 276
A PSEYE+IAFQYG+TDLRGMLKRLK MRR+EKKS AF K L+PAYQV KG ++R VEL
Sbjct: 328 APPSEYERIAFQYGVTDLRGMLKRLKGMRRDEKKSTAFQKKLEPAYQVSKGHKIRLTVEL 387
Query: 277 ADPKLEVKWYKNGQEIRPS-TKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTEL 335
AD EVKW KNGQEI+ S +KYIFE G +R L I+ C + DD+ Y G EKCSTEL
Sbjct: 388 ADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCSTEL 447
Query: 336 FVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEG 395
FV+EPP+++T+ LED G+RVE ECEVSE+ A VKW K+G E+ +YR + +G
Sbjct: 448 FVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDG 507
Query: 396 KKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCE 455
++H LII A DA Y++ T+GGQ+ A+L V K L++ + D V + KCE
Sbjct: 508 QRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVFKCE 567
Query: 456 IS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPA 514
+S EN+ G W KNG + R+KV H GR+HKL I + DE DY F P+ + L A
Sbjct: 568 VSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSA 627
Query: 515 KVHVID----------PPKIILD--GLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSR- 561
K+H ++ PPKI LD G D T+ V+AGNKLRL++PISG+P P +W +
Sbjct: 628 KLHFMEVKIDFVPRQEPPKIHLDCPGRIPD-TIVVVAGNKLRLDVPISGDPAPTVIWQKA 686
Query: 562 -------------------GD--------KAIMEGSGRIRTESYPDSSTLVIDIAERDDS 594
GD K + E GR+R E+ D S ++ AE++D
Sbjct: 687 ITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDE 746
Query: 595 GVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGY 654
GVY + +KN GE ++ VKV+D PD P AP ++ VG+D C + WEPPAYDGG PILGY
Sbjct: 747 GVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGY 806
Query: 655 FIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVP 714
+ERKKK+S RWMRLNFDL +E + E ++MIEGV YE+R++AVNAIG+S+PS S+PF+P
Sbjct: 807 ILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMP 866
Query: 715 LAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAA 774
+ S PT L V+ V+DTTV+++WRPP+ +GA GLDGY +EYC EG +
Sbjct: 867 IGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCS------------ 914
Query: 775 YDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEII 834
+W+ A + L + T + LPT A++ RV+A N AG P ++P+ V+EI+
Sbjct: 915 ------EWVAALQGLTEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEIL 968
Query: 835 EPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDT 894
+ P++++PRHL+QT ++VGE VNL+IPFQGKPRP++TW K+G + +++IRNS TDT
Sbjct: 969 QRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDT 1028
Query: 895 IIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTP 954
I+FIR A R HSG Y + V+++ + A++ +Q++D+P PPQ +++ D WG NVAL W P
Sbjct: 1029 ILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKP 1088
Query: 955 PKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLS 1014
P+D GN + GYT+QKADKK+MEWFTV+EHY RT + EL+IGN YYFRVFS+NM G S
Sbjct: 1089 PQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFS 1148
Query: 1015 EDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNP 1074
+ A TKE I R G Y+ P Y+ DFSEAP FTQPLVN IAGY A L C+VRG+P
Sbjct: 1149 DRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSP 1208
Query: 1075 KPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKL 1134
KPKI+W KN + + +D R+RMFS QGV TLEIRKP P+DGG Y C+A N G EC+L
Sbjct: 1209 KPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRL 1268
Query: 1135 EVKV 1138
EV+V
Sbjct: 1269 EVRV 1272
Score = 39.3 bits (90), Expect = 0.022
Identities = 33/131 (25%), Positives = 51/131 (38%), Gaps = 6/131 (4%)
Query: 248 EKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQR 307
+K +AF+K + +V G F E ++V+W + G +I S KY +G +
Sbjct: 6 KKPVSAFSK-KPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRH 64
Query: 308 ILFINNCQMTDDSEYYVTAGDEKCSTELFV-----REPPIMVTKQLEDTTAYCGERVELE 362
L + D Y V AG K +L V EP + + T GE
Sbjct: 65 TLTVREVGPADQGSYAVIAGSSKVKFDLKVIEAEKAEPMLAPAPAPAEATGAPGEAPAPA 124
Query: 363 CEVSEDDANVK 373
E+ E + K
Sbjct: 125 AELGESAPSPK 135
Score = 39.3 bits (90), Expect = 0.022
Identities = 23/97 (23%), Positives = 41/97 (42%), Gaps = 6/97 (6%)
Query: 338 REPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKK 397
++P +K+ G E E V+W + G +I ++Y + EG +
Sbjct: 6 KKPVSAFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDI--SASNKYGLATEGTR 63
Query: 398 HILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLK 434
H L + AD Y+V+ S+K+ DLK ++
Sbjct: 64 HTLTVREVGPADQGSYAVIA----GSSKVKFDLKVIE 96
>gi|55956914 myosin binding protein H [Homo sapiens]
Length = 477
Score = 448 bits (1153), Expect = e-125
Identities = 222/445 (49%), Positives = 294/445 (66%), Gaps = 23/445 (5%)
Query: 696 AVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLE 755
A A +KP+ PS V S P LLT+D V+ ++VT+ W PP+ +G GL GYVLE
Sbjct: 54 APTASTATKPAPPSED-----VPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLE 108
Query: 756 YCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNA 815
C EG A +W+ + + T+ T+ L K +RV AV++
Sbjct: 109 LCREG------------------ASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSS 150
Query: 816 AGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKK 875
AGA P QPI ++E IE PKIR+PRHL+QTYIR+VGE VNL IPFQGKP+P+ TW
Sbjct: 151 AGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTH 210
Query: 876 DGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPP 935
+G +D ++++R + D+I+FIR A+RS SG+Y+L V+V+ A IDI +I++PGPP
Sbjct: 211 NGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPP 270
Query: 936 QIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITEL 995
+++ DVWG N AL WTPP+D GN + GY +QKADKK+ +WFTV+E YH T+ TI++L
Sbjct: 271 SSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDL 330
Query: 996 VIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVN 1055
+IGN Y FRVFSEN+CGLS AT+TKE A I + K + + DFSEAP FTQPL +
Sbjct: 331 IIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLAD 390
Query: 1056 TYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGG 1115
+ GY+ L CSVR +PKPKI WMKNK+ I +P+YR S QGVCTLEIRKPSP+D G
Sbjct: 391 HTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSG 450
Query: 1116 TYCCKAVNDLGTVEIECKLEVKVIA 1140
Y CKA+N LG ++C+LEVK A
Sbjct: 451 VYTCKAINVLGEASVDCRLEVKASA 475
Score = 89.7 bits (221), Expect = 1e-17
Identities = 50/164 (30%), Positives = 84/164 (51%), Gaps = 3/164 (1%)
Query: 540 GNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHI 599
G + L+IP G+P P+A W+ A+ S R+ + S L I A+R DSG Y +
Sbjct: 189 GETVNLQIPFQGKPKPQATWTHNGHAL--DSQRVSMRTGDQDSILFIRSAQRSDSGRYEL 246
Query: 600 NLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERK 659
++ E EA A I + V++ P PP + + +V + W PP G + +LGY +++
Sbjct: 247 TVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKA 306
Query: 660 KKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGIS 703
K++ +W + + TT +I G +Y R+F+ N G+S
Sbjct: 307 DKKTGQWFTV-LERYHPTTCTISDLIIGNSYSFRVFSENLCGLS 349
Score = 45.1 bits (105), Expect = 4e-04
Identities = 24/94 (25%), Positives = 46/94 (48%)
Query: 618 DFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKET 677
D P P+ T+ +V ++WEPP G + GY +E ++ +S W+ ++ T
Sbjct: 69 DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128
Query: 678 TFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRP 711
+ + G + +R+ AV++ G P+M +P
Sbjct: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQP 162
Score = 38.9 bits (89), Expect = 0.028
Identities = 73/314 (23%), Positives = 118/314 (37%), Gaps = 45/314 (14%)
Query: 337 VREPPIMVTKQLEDT-TAYCGERVELECEVS-EDDANVKWFKNGEEIIPGPKSRYRIRVE 394
+ P I V + L T GE V L+ + W NG + R +R
Sbjct: 169 IEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL---DSQRVSMRTG 225
Query: 395 GKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNL----GKEI 450
+ IL I A ++D+ Y + AK +D+ L I P ++ L G
Sbjct: 226 DQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDI--LVIEKPGPPSSIRLLDVWGCNA 283
Query: 451 CLKCEISENIPGKWTKNGLPVQESDR--------LKVVHKGR--IHKLVIANALTEDEGD 500
L+ ++ G G VQ++D+ L+ H I L+I N+ +
Sbjct: 284 ALQWTPPQDT-GNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFR--- 339
Query: 501 YVFAPDAYNVTLPA----------KVHVIDPPK--IILDGLDADNTVTVIA------GNK 542
VF+ + ++ A K + PK I D +A + +A G
Sbjct: 340 -VFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYS 398
Query: 543 LRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLK 602
+L + P PK +W + +K ++G+ + R S TL I DSGVY
Sbjct: 399 TQLFCSVRASPKPKIIWMK-NKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAI 457
Query: 603 NEAGEAHASIKVKV 616
N GEA +++V
Sbjct: 458 NVLGEASVDCRLEV 471
>gi|194018539 myosin binding protein H-like [Homo sapiens]
Length = 354
Score = 375 bits (963), Expect = e-103
Identities = 172/322 (53%), Positives = 232/322 (72%), Gaps = 4/322 (1%)
Query: 817 GASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKD 876
GA P P L+ I E PKI +PR L+QTYIR+VG+ VNL+IPFQGKP+P+ W D
Sbjct: 35 GAGSPT----PQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHD 90
Query: 877 GAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ 936
G +D ++++RN E D+I+FIR+A+R+ SG+Y L+V++ TA+IDI +I+RPGPPQ
Sbjct: 91 GCALDTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQ 150
Query: 937 IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELV 996
+K+ DVWG + L WTPP+D GN A+ GYT+QKAD KS WFTV+EHYHRTS +++L+
Sbjct: 151 SIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLI 210
Query: 997 IGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNT 1056
IGN Y FRVF+EN CGLSE A +T + A I + +YK + DFSEAP FTQPL +
Sbjct: 211 IGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQPLADC 270
Query: 1057 YAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGT 1116
+ GYN L C VR +P+PKI W+KNK+ I +P+YR ++ G+C+LEIRKP P+DGG
Sbjct: 271 TTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGI 330
Query: 1117 YCCKAVNDLGTVEIECKLEVKV 1138
Y CKAVN LG ++C+++VKV
Sbjct: 331 YTCKAVNPLGEASVDCRVDVKV 352
Score = 81.3 bits (199), Expect = 5e-15
Identities = 48/165 (29%), Positives = 84/165 (50%), Gaps = 3/165 (1%)
Query: 540 GNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHI 599
G+ + L IP G+P P+A+W+ A+ + R+ + S L I A+R DSG Y +
Sbjct: 68 GDTVNLLIPFQGKPKPQAIWTHDGCAL--DTRRVSVRNGEQDSILFIREAQRADSGRYQL 125
Query: 600 NLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERK 659
++ EA A+I + V++ P PP + + +V + W PP G + +LGY +++
Sbjct: 126 RVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKA 185
Query: 660 KKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISK 704
+S W + + T+ +I G +Y R+FA N G+S+
Sbjct: 186 DTKSGLWFTV-LEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE 229
Score = 34.7 bits (78), Expect = 0.53
Identities = 57/260 (21%), Positives = 93/260 (35%), Gaps = 38/260 (14%)
Query: 388 RYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLG 447
R +R + IL I A +AD+ Y + G A ++D+ L I P Q++ L
Sbjct: 98 RVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDI--LVIERPGPPQSIKLV 155
Query: 448 KEICLKCEISENIP---GKWTKNGLPVQESDR--------LKVVHKGR--IHKLVIANA- 493
+ P G G VQ++D L+ H+ + L+I N+
Sbjct: 156 DVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSY 215
Query: 494 -----------------LTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVT 536
+T D A Y A+ + PK D T
Sbjct: 216 AFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQPLADC----T 271
Query: 537 VIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGV 596
+ G +L + P PK +W + +K ++G+ + R ++ +L I D G+
Sbjct: 272 TVTGYNTQLFCCVRASPRPKIIWLK-NKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGI 330
Query: 597 YHINLKNEAGEAHASIKVKV 616
Y N GEA +V V
Sbjct: 331 YTCKAVNPLGEASVDCRVDV 350
>gi|253970427 immunoglobulin superfamily, member 22 [Homo sapiens]
Length = 1326
Score = 291 bits (744), Expect = 3e-78
Identities = 245/906 (27%), Positives = 381/906 (42%), Gaps = 64/906 (7%)
Query: 263 QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 322
+V + R EL + ++W K+GQ + TKY H+G + L I + Q++D EY
Sbjct: 429 RVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEY 488
Query: 323 YVTAGDEKCSTELF------VREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFK 376
V A + TE + V E V + D A G EL ++++ W K
Sbjct: 489 TVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLK 548
Query: 377 NGEEI--IPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPL- 433
+G+EI +PG +I +G H LI +Y+ G +S A + + P
Sbjct: 549 DGKEITDLPG----MQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTI 604
Query: 434 --KILTPLTDQ--TVNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIHK 487
+L L TV +G +K K W K+G+ V E +R+ +
Sbjct: 605 DPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQAL 664
Query: 488 LVIANALTEDEGDYVFA--PDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRL 545
L I+N + ED G + D + T + V+D PK ++ K +
Sbjct: 665 LTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKA 724
Query: 546 EIPISGEPPPKAMWSR---GDKA---IMEGSGRIR---TESYPDSSTLVIDIAERDDSGV 596
G P + + R G K+ I E G++ T + I + GV
Sbjct: 725 PKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGV 784
Query: 597 YHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFI 656
++ E ++ P P VT+V + + W P DGG+P+LGY +
Sbjct: 785 ------SDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIV 838
Query: 657 ERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLA 716
ER+KK S+ W+ +N D + T ++E YE R+ AVN G +PS+PS V
Sbjct: 839 ERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKD 898
Query: 717 VTSPPTL---LTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEA 773
PP L L V +++++++ WR P GY+LE E +
Sbjct: 899 PVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAEDT------------ 944
Query: 774 AYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEI 833
++W K I T +T+ GL K F R++AVN AG EP + +
Sbjct: 945 ------KEWSKCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPP 998
Query: 834 IEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETD 893
PK + LK + R G A+ + F G P P++ W+KDG K + I S+
Sbjct: 999 PAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQKDGVP-TKGRETITKSKNH 1057
Query: 894 TIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWT 953
+ I +RS SG Y + ++ + I +++ D P PP +++ + V LTW
Sbjct: 1058 SQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWN 1117
Query: 954 PPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL 1013
D Y I K D + W+T E T+T L+ G +YYFRV + N G
Sbjct: 1118 HSPDVQEDGEAHYIIMKRDASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGD 1177
Query: 1014 SEDATMTKESAVIARD---GKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSV 1070
SE ++++ +I +D K YE D+ AP F PL + G + T+ C+
Sbjct: 1178 SEPLD-SRDTWLINKDQIQDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAF 1236
Query: 1071 RGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEI 1130
GNP+P +T K V I + ++ S GVCTL I + D G Y N+LG
Sbjct: 1237 LGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRS 1296
Query: 1131 ECKLEV 1136
C L V
Sbjct: 1297 SCTLTV 1302
Score = 251 bits (642), Expect = 2e-66
Identities = 230/941 (24%), Positives = 389/941 (41%), Gaps = 150/941 (15%)
Query: 20 EEPSKEKEAGTTPAKDWTLVETPPGEEQAKQNANSQLSIL-----------------FIE 62
E S E + TT + ++ GEE ++ ++S + F+E
Sbjct: 12 EHVSMEFSSSTTHVQTFSQTTKIVGEEVVRRKSSSIVEFFSLVTRSSNIPAGDSVPEFVE 71
Query: 63 KPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAG--------KHLQLKE 114
KPQ T G+ F A+V+ KP I W + + + A +H+ E
Sbjct: 72 KPQPVTAPEGDKAVFRARVQGN---AKPHISWKRESGIPIKESAKIFYDSINKEHVLKLE 128
Query: 115 TF--------------ERHSRVYTFEMQIIKAKDNFAGNY----RCEVTYKDKFDSCSFD 156
+ +YT + + + ++ R K K + +
Sbjct: 129 PLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKMDFKKMLKKRAPPAPKKKQKKVANE 188
Query: 157 LEVHESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLKN 216
E+ E P D + G DF GLL R++K+ +++ +V+ +LK
Sbjct: 189 KEMLEILSKVPKKDFEKVCM-------EYGFTDFRGLL--RKLKEMKKKVEVEAIRILKP 239
Query: 217 AKPSEYE-----------------------------KIAFQYGITDLRGMLKR------- 240
+ E + +I + G D++ M +
Sbjct: 240 LEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPLRIQYSLGKYDVKQMGTKYMLVISN 299
Query: 241 -------LKRMRREEKKSAAFAKILDPAYQ---------VDKGGRVRFVVELADPKLEVK 284
+ + +K+ +A +LD + V + F + L+ +
Sbjct: 300 VNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSKKEPNFV 359
Query: 285 WYKNGQEIRPSTKY--IFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPI 342
W NG+E++ KY G L I + +++D E+ AG+ +L + PI
Sbjct: 360 WKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQLTIDRIPI 419
Query: 343 MVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILII 402
L++ R LECE++ D ++W K+G+ ++ G K Y + EGK+ LII
Sbjct: 420 KFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTK--YSMNHEGKRAELII 477
Query: 403 EGATKADAAEYSVMT------TGGQSSAKLSVDLKPLKILTPLTDQTVNLGK--EICLKC 454
E A +D EY+V+ T S+A ++V+ + + + ++D G E+C+
Sbjct: 478 EDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVL 537
Query: 455 EISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPA 514
E + G W K+G + + +++V +G +HKL+ + E EG Y F A A
Sbjct: 538 N-DEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKYTFR--AKGTESEA 594
Query: 515 KVHVIDPPKI---ILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSG 571
V + DPP I +L+ L A + +TV G+ +++P G+P PK W + + E
Sbjct: 595 SVFIADPPTIDPSVLEALAA-HAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEE- 652
Query: 572 RIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT-VTE 630
R+ E D + L I R+DSG+ + LKN+ G A A++ + V+D P PP E
Sbjct: 653 RVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLE 712
Query: 631 VGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAY 690
+ M W+ P +GG P+ + +ER+ W+++ K T F K+ EG AY
Sbjct: 713 LSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAY 772
Query: 691 EVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTT---VTMRWRPPDHIGAA 747
+ RI AVN+ G+S P F + PP + VTD T VT+ W P G A
Sbjct: 773 QFRILAVNSEGVSDPLETEEVFAGNPI-EPPGFASQPQVTDVTKEAVTITWNAPTQDGGA 831
Query: 748 GLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIF 807
+ GY++E +GS W+ NKD I TK T+ GL D +
Sbjct: 832 PVLGYIVERRKKGSNL------------------WVPVNKDPIQGTKCTVDGLLEDTEYE 873
Query: 808 VRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQT 848
RV AVN AG +P S ++ K+ ++PP + H+ +
Sbjct: 874 FRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDS 914
Score = 41.6 bits (96), Expect = 0.004
Identities = 29/95 (30%), Positives = 41/95 (43%), Gaps = 1/95 (1%)
Query: 536 TVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSG 595
TV+ G + G P P +GD I S + S TLVI DSG
Sbjct: 1223 TVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANS-KFWYNSTSGVCTLVIPTCTLKDSG 1281
Query: 596 VYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTE 630
Y + ++NE G+ +S + V D D V ++TE
Sbjct: 1282 DYSVLVENELGKDRSSCTLTVYDKDDKSVVASITE 1316
Score = 30.8 bits (68), Expect = 7.7
Identities = 27/124 (21%), Positives = 48/124 (38%), Gaps = 3/124 (2%)
Query: 1002 YFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAG 1061
+ + FS+ + E+ K S+++ + ++ D P F + A G
Sbjct: 24 HVQTFSQTTKIVGEEVVRRKSSSIVEFFSLVTRSSNIPAGD--SVPEFVEKPQPVTAPEG 81
Query: 1062 YNATLNCSVRGNPKPKITWMKNK-VAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCK 1120
A V+GN KP I+W + + I + + S L++ + D Y C
Sbjct: 82 DKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKLEPLTSDDSDNYKCI 141
Query: 1121 AVND 1124
A ND
Sbjct: 142 ASND 145
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 288 bits (738), Expect = 2e-77
Identities = 218/774 (28%), Positives = 346/774 (44%), Gaps = 70/774 (9%)
Query: 272 FVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKC 331
F +L+ K VKWY+NG+EI+ KY FE G L I +C++ D+ EY D K
Sbjct: 12842 FSCQLSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYACGVEDRKS 12901
Query: 332 STELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRI 391
LFV E P+ + + +D G V E+++D V+W +N ++ G K +++
Sbjct: 12902 RARLFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQWLRNNMVVVQGDK--HQM 12959
Query: 392 RVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEIC 451
EGK H L I D EY + ++ AKL + P KI T D V++GK +
Sbjct: 12960 MSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLELAAAP-KIKTADQDLVVDVGKPLT 13018
Query: 452 LKC--EISENIPGKWTKNGLPV----------QESDRL---KVVHKGRIHKLVIANALTE 496
+ + +W K P+ Q S R+ K KGR +K+V+ N +
Sbjct: 13019 MVVPYDAYPKAEAEWFKENEPLSTKTIDTTAEQTSFRILEAKKGDKGR-YKIVLQNKHGK 13077
Query: 497 DEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPK 556
EG + VID P + + + T T L E P++
Sbjct: 13078 AEGFI-------------NLKVIDVPGPVRN---LEVTETFDGEVSLAWEEPLTDGGSKI 13121
Query: 557 AMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG-----EAHAS 611
+ + I + + T+ V + + ++ ++ +N G E
Sbjct: 13122 IGYVVERRDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNP 13181
Query: 612 IKVKV-VDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLN 670
++ + D P PP+ T+T+V + WEPP YDGG+ I Y IE + K S RW
Sbjct: 13182 VEARSKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAM 13241
Query: 671 FDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV----PLAVTSPPTLLTV 726
++ + ++EG Y R+ A N IG+ KPS + PFV P+ SPP LT
Sbjct: 13242 TVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAAT-PFVKVADPIERPSPPVNLTS 13300
Query: 727 DSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVAN 786
T ++V ++W PP G + + GY++E C EG ++WI N
Sbjct: 13301 SDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGK------------------DNWIRCN 13342
Query: 787 KDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLK 846
L+ + + +TGL K RV A N AG S+P P+ + P + + K
Sbjct: 13343 MKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSA-FK 13401
Query: 847 QTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDK-NQINIRNSETDTIIFIRKAERSH 905
V + +++P G PRP TW ++ +++ ++ + I +ERS
Sbjct: 13402 DGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSD 13461
Query: 906 SGKYDLQVKVDKFVETAS--IDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAI 963
G Y L K++ V+T S ID+ +I RP P+ +K D+ ++V LTW PP DDG + +
Sbjct: 13462 KGIYTL--KLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPL 13519
Query: 964 TGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDA 1017
TGY ++K + W V++ T+ +LV G EY F+V + N CG E A
Sbjct: 13520 TGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 13573
Score = 278 bits (711), Expect = 2e-74
Identities = 166/521 (31%), Positives = 269/521 (51%), Gaps = 35/521 (6%)
Query: 511 TLPAKVHV---IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIM 567
TLP V I+PP+I LD D V + A LRL + I G P P+ W + + +
Sbjct: 25091 TLPGSVVAQERIEPPEIELDA-DLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILT 25149
Query: 568 EGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT 627
+ R + E + LVID R DSG Y++ L+N +G A + V+V+D P PV T
Sbjct: 25150 D---RAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLT 25206
Query: 628 VTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEG 687
+ EV D ++WEPP DGG+ I Y +E+++ + + + C +TTF + + EG
Sbjct: 25207 IREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNN-CTKTTFRIENLQEG 25265
Query: 688 VAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAA 747
+Y R+ A N GI P+ + P PP +T+ VT T T++W P+ G +
Sbjct: 25266 CSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGS 25325
Query: 748 GLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIF 807
+ GYV+E +GS E W + + + TI+GL +
Sbjct: 25326 KITGYVVEMQTKGS------------------EKWSTCTQ--VKTLEATISGLTAGEEYV 25365
Query: 808 VRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKP 867
RV AVN G S+P+ P++ ++I P + +P H T+ + E + + +PF+G+P
Sbjct: 25366 FRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFH---TFNVKAREQLKIDVPFKGRP 25422
Query: 868 RPELTWKKDGAEI-DKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDI 926
+ + W+KDG + + ++N+ +S+T T + I++A + G Y+L V T I I
Sbjct: 25423 QATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITI 25482
Query: 927 QIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYH 986
++DRPGPP ++I++V +++ ++W PP+ DG I+ Y ++K + S W V +
Sbjct: 25483 IVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVA 25542
Query: 987 RTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIA 1027
RTS I L G+EY FRV +EN G S + ++ SAV+A
Sbjct: 25543 RTSIKIVRLTTGSEYQFRVCAENRYGKS---SYSESSAVVA 25580
Score = 270 bits (691), Expect = 4e-72
Identities = 179/588 (30%), Positives = 288/588 (48%), Gaps = 53/588 (9%)
Query: 438 PLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQ------ESDRLKVVHKGRIHKLVIA 491
P+ D + I KC++S G+WT P E ++L H+ I
Sbjct: 22861 PIYDGGCEIQGYIVEKCDVSV---GEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAIN 22917
Query: 492 NALTEDEGDYVFAPDAYNVTLPAKVHV---IDPPKIILDGLDADNTVTVIAGNKLRLEIP 548
A + D +P + V ++ P I LD L+ + + AG LRL +P
Sbjct: 22918 KAGVGEHAD-----------VPGPIIVEEKLEAPDIDLD-LELRKIINIRAGGSLRLFVP 22965
Query: 549 ISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEA 608
I G P P+ W + D I + + T S+ ++LV+D R DSG Y + L+N +G
Sbjct: 22966 IKGRPTPEVKWGKVDGEIRDAAIIDVTSSF---TSLVLDNVNRYDSGKYTLTLENSSGTK 23022
Query: 609 HASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMR 668
A + V+V+D P PPV VTE+ D + WEPP DGGS I Y +E+++ +
Sbjct: 23023 SAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAA 23082
Query: 669 LNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDS 728
+ + C + +++ ++ EG +Y R+ A N GI P+ + P V PP +TVD
Sbjct: 23083 VVTN-CHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDD 23141
Query: 729 VTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKD 788
VT +V++ W P+H G + + Y++E AK S++ E A
Sbjct: 23142 VTRNSVSLSWTKPEHDGGSKIIQYIVE------MQAKHSEKWSECA-------------- 23181
Query: 789 LIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQT 848
+ + IT L + RV AVN G S+P+ + PI+ K+++ P + + +
Sbjct: 23182 RVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDV---KPAFSS 23238
Query: 849 YIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDK-NQINIRNSETDTIIFIRKAERSHSG 907
Y +VG+ + + +P G+P+P +TW KDG + + +IN+ +S T + I++ + G
Sbjct: 23239 YSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGG 23298
Query: 908 KYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWGENVALTWTPPKDDGNAAITGY 966
+Y + V +TASI+I +D+P PP+ VK +DV E++ L+W PP G IT Y
Sbjct: 23299 QYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNY 23358
Query: 967 TIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLS 1014
+QK D + W V RT+ +T+L G EY FR+F+EN G S
Sbjct: 23359 IVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQS 23406
Score = 259 bits (662), Expect = 1e-68
Identities = 158/580 (27%), Positives = 280/580 (48%), Gaps = 37/580 (6%)
Query: 519 IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESY 578
++ P++ LD + + V AG R+ IP G P P+ WSR + E + +++ E
Sbjct: 24019 LEAPELDLDS-ELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEG---EFTDKVQIEKG 24074
Query: 579 PDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIM 638
+ + L ID +R+D+G Y + L+N +G A + VKV+D P PP V EV D +
Sbjct: 24075 VNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFL 24134
Query: 639 NWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVN 698
WEPP DGG+ + Y I++++ + ++ C +T+F+ + + EG Y R+ A N
Sbjct: 24135 VWEPPIIDGGAKVKNYVIDKRESTRKAYANVS-SKCSKTSFKVENLTEGAIYYFRVMAEN 24193
Query: 699 AIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCF 758
G+ P SPP +T+ V+ T+ ++ W P+H G + + GYV+E
Sbjct: 24194 EFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQP 24253
Query: 759 EGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGA 818
+G+ E W + + + +TGL + + RVKA N G
Sbjct: 24254 KGT------------------EKWSIVAESKV--CNAVVTGLSSGQEYQFRVKAYNEKGK 24293
Query: 819 SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGA 878
S+P+ P++ K++ P +++P + TY + GE + + IP G+PRP ++W KDG
Sbjct: 24294 SDPRVLGVPVIAKDLTIQPSLKLPFN---TYSIQAGEDLKIEIPVIGRPRPNISWVKDGE 24350
Query: 879 EIDK-NQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPP-Q 936
+ + ++N+ + T T++ I++ + GKY + T ++ + ++++PGPP
Sbjct: 24351 PLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVG 24410
Query: 937 IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELV 996
V+ ++V + V ++W PP G I+ Y ++K D + W V RT+ IT+L
Sbjct: 24411 PVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTIKITKLK 24470
Query: 997 IGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNT 1056
G EY FR+F+EN G S A + ++ ++ +K P F + Q LV
Sbjct: 24471 TGTEYQFRIFAENRYGKS--APLDSKAVIVQYP---FKEPGPPGTPFVTSISKDQMLVQW 24525
Query: 1057 YAIAGYNAT--LNCSVRGNPKPKITWMKNKVAIVDDPRYR 1094
+ T + + K I W+K + D +++
Sbjct: 24526 HEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFK 24565
Score = 248 bits (632), Expect = 3e-65
Identities = 149/496 (30%), Positives = 252/496 (50%), Gaps = 30/496 (6%)
Query: 521 PPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPD 580
PP+I LD D VT+ A LRL +PI G P P+ W+R ++ + T SY
Sbjct: 21857 PPEIELDA-DLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESLDKASIESTSSY-- 21913
Query: 581 SSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNW 640
+ L++ R DSG Y + ++N +G A + V+V+D P PP V EV + W
Sbjct: 21914 -TLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTW 21972
Query: 641 EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAI 700
+PP DGGS I Y +E+++ + + + C +T+++ ++ EG +Y R+ A N
Sbjct: 21973 DPPLLDGGSKIKNYIVEKRESTRKAYSTVATN-CHKTSWKVDQLQEGCSYYFRVLAENEY 22031
Query: 701 GISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEG 760
GI P+ + PP +T+ VT +V++ W P+H G + + GY++E +G
Sbjct: 22032 GIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKG 22091
Query: 761 STSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASE 820
S + W A + T+ TITGL + RV A N G S+
Sbjct: 22092 S------------------DKW--ATCATVKVTEATITGLIQGEEYSFRVSAQNEKGISD 22131
Query: 821 PKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI 880
P+ S P++ K+++ PP ++ L T+ GE + + +PF G+P P +TW KD +
Sbjct: 22132 PRQLSVPVIAKDLVIPPAFKL---LFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPL 22188
Query: 881 DK-NQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IV 938
+ ++N ++E ++++ I+ A R G Y +++ ++++ ++D+PGPP V
Sbjct: 22189 KQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPV 22248
Query: 939 KIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIG 998
K+++V +++ L+W PPK DG ++I Y ++K D + W V RT+ L G
Sbjct: 22249 KMDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVSATVARTTIKACRLKTG 22308
Query: 999 NEYYFRVFSENMCGLS 1014
EY FR+ +EN G S
Sbjct: 22309 CEYQFRIAAENRYGKS 22324
Score = 244 bits (624), Expect = 3e-64
Identities = 156/511 (30%), Positives = 243/511 (47%), Gaps = 35/511 (6%)
Query: 518 VIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRG--DKAIMEGSGRIRT 575
+++PP+I LD V V AG +RL + G P PK W + D + +G +
Sbjct: 18600 ILEPPEIDLDA-SMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKG----QV 18654
Query: 576 ESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDW 635
+ + LVI + RDDSG Y + L N AGE + V+V+D P P V++V
Sbjct: 18655 DLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTS 18714
Query: 636 CIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIF 695
C ++W PP DGGS + Y +E+++ W + ++ K+T+F ++ G Y R+
Sbjct: 18715 CHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEV-KKTSFHVTNLVPGNEYYFRVT 18773
Query: 696 AVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGY 752
AVN G P+ +P + PL+ PP L V +T + T+ W PP G A +DGY
Sbjct: 18774 AVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGY 18833
Query: 753 VLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKA 812
+ Y E + PA+ W ++ +TGL K RV A
Sbjct: 18834 ITSYREE----------------EQPADRW--TEYSVVKDLSLVVTGLKEGKKYKFRVAA 18875
Query: 813 VNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELT 872
NA G S P+ KE + PPKI +P + + G+ + + GKP P
Sbjct: 18876 RNAVGVSLPREAEGVYEAKEQLLPPKILMPEQI----TIKAGKKLRIEAHVYGKPHPTCK 18931
Query: 873 WKKDGAE-IDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDR 931
WKK E + + + + +++ +I+ I+ R SG Y L + +T I + ++D
Sbjct: 18932 WKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDA 18991
Query: 932 PGPPQ-IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSA 990
PGPPQ I D+ + +L+W P +DG + IT Y ++K D +W T + +TS
Sbjct: 18992 PGPPQPPFDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSC 19051
Query: 991 TITELVIGNEYYFRVFSENMCGLSEDATMTK 1021
+ +L+ G EY FRV +EN G+SE T K
Sbjct: 19052 RVGKLIPGQEYIFRVRAENRFGISEPLTSPK 19082
Score = 244 bits (623), Expect = 3e-64
Identities = 143/488 (29%), Positives = 242/488 (49%), Gaps = 34/488 (6%)
Query: 534 TVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSS----TLVIDIA 589
T+ V AG + +P G P P +WS+ D + RT +Y D++ +L I+ A
Sbjct: 26195 TLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDL-------RTRAYVDTTDSRTSLTIENA 26247
Query: 590 ERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGS 649
R+DSG Y + ++N A ++ VKV+D P PP TV +V + +++W+ P DGG+
Sbjct: 26248 NRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGA 26307
Query: 650 PILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPS 709
P+ Y IE+++ W+ + + C +++ + EG Y R+ N G+ P+
Sbjct: 26308 PVKNYHIEKREASKKAWVSVT-NNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETK 26366
Query: 710 RPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDE 769
SPP L V S++ +V++ W P+H G + + YV+E +G
Sbjct: 26367 EGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQ-------- 26418
Query: 770 NGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPIL 829
++W+ + T ++GL +++ F RV A N AG S+P+ P+L
Sbjct: 26419 ----------KNWVKC--AVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVL 26466
Query: 830 VKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKN-QINIR 888
+KE +EPP+I + T R G + + IP GKP P++T +DG + + N
Sbjct: 26467 IKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTE 26526
Query: 889 NSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWGEN 947
+ + I ++++ + +G+Y++ A I+I ++DRPGPP V I D+ E+
Sbjct: 26527 ITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDITEES 26586
Query: 948 VALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFS 1007
V L W PPK DG + +T Y + K + + W V RT + +L G EY FR+ +
Sbjct: 26587 VTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKA 26646
Query: 1008 ENMCGLSE 1015
EN G+S+
Sbjct: 26647 ENRFGISD 26654
Score = 244 bits (622), Expect = 4e-64
Identities = 157/500 (31%), Positives = 254/500 (50%), Gaps = 31/500 (6%)
Query: 522 PKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS 581
P + LD D V V AG +R+ +SG+PPP W+ ++ + + + E+ S
Sbjct: 16522 PDLQLDASVRDRIV-VHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEA---TIETTAIS 16577
Query: 582 STLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTE-VGDDWCIMNW 640
S++VI +R GVY + KNEAGE +I V V+D P P P + + ++ C + W
Sbjct: 16578 SSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTW 16637
Query: 641 EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAI 700
P DGGSPI Y IE+++ W + + + ++ + +I+G AY RI A N+I
Sbjct: 16638 FSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNA-TVQGLIQGKAYFFRIAAENSI 16696
Query: 701 GISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 757
G+ S V P+ V P L V VT TVT+ W PP + G + + YVLE
Sbjct: 16697 GMGPFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESR 16756
Query: 758 FEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAG 817
G+ + V N +L+ + K+T+ GL RV AVN G
Sbjct: 16757 LIGTEKFHK-----------------VTNDNLLSR-KYTVKGLKEGDTYEYRVSAVNIVG 16798
Query: 818 ASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDG 877
+P + ++PI K+ + PP + + K T RVGEA L + GKP+P+++W KD
Sbjct: 16799 QGKPSFCTKPITCKDELAPPTLHLDFRDKLTI--RVGEAFALTGRYSGKPKPKVSWFKDE 16856
Query: 878 AEI-DKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ 936
A++ + ++ +I+ + + KA+RS SGKY + V+ + ++DRPGPP
Sbjct: 16857 ADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPV 16916
Query: 937 -IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITEL 995
V ++V + + ++W PP DDG + IT Y I+K + W V +T+ +++L
Sbjct: 16917 GPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKL 16976
Query: 996 VIGNEYYFRVFSENMCGLSE 1015
+ G +Y FR+ +EN+ G+S+
Sbjct: 16977 LEGKDYIFRIHAENLYGISD 16996
Score = 239 bits (611), Expect = 8e-63
Identities = 151/488 (30%), Positives = 240/488 (49%), Gaps = 28/488 (5%)
Query: 530 DADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIA 589
D TVT+ AG LRL + +SG PPP WS+ + + TESY S L++D
Sbjct: 29451 DLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESY---SLLIVDKV 29507
Query: 590 ERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGS 649
R D+G Y I +N++G+ A++ VKV D P P + V EV D + WE P DGG+
Sbjct: 29508 NRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGA 29567
Query: 650 PILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPS 709
P+ Y +E K++ + R + C +T + ++EG Y R+ N GI +P S
Sbjct: 29568 PVNNYIVE-KREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETS 29626
Query: 710 RPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDE 769
+ V P L V VT +TVT+ W P + G + L GYVLE C G+
Sbjct: 29627 DAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGT-------- 29678
Query: 770 NGEAAYDLPAEDW--IVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQP 827
E W +V K + + T+T L + R++A N G SEP+
Sbjct: 29679 ----------ERWMKVVTLKPTV--LEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTA 29726
Query: 828 ILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI-DKNQIN 886
+ V+++ P I + ++T G V LVIP G+P P +W G+++ + ++
Sbjct: 29727 VTVQDLRVLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVT 29786
Query: 887 IRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWG 945
+ + IR+ +G+Y L++K + +I + I+D+PGPP +KI+++
Sbjct: 29787 VETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDA 29846
Query: 946 ENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRV 1005
++ ++W PP+ DG A ++GY +++ D W V E R++ T L GNEY FRV
Sbjct: 29847 TSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRV 29906
Query: 1006 FSENMCGL 1013
+ N G+
Sbjct: 29907 AATNRFGI 29914
Score = 239 bits (610), Expect = 1e-62
Identities = 152/526 (28%), Positives = 245/526 (46%), Gaps = 40/526 (7%)
Query: 508 YNVTLPAKVHVIDPPKIILDGLDADNT--------------VTVIAGNKLRLEIPISGEP 553
Y V+ K V DP +I L L AD+ + VI N + + +P +G P
Sbjct: 13364 YRVSAENKAGVSDPSEI-LGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYP 13422
Query: 554 PPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIK 613
P A W GDK ++E R++ ++ + LVI +ER D G+Y + L+N I
Sbjct: 13423 RPTATWCFGDK-VLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEID 13481
Query: 614 VKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDL 673
V V+ P P ++ D + WEPP DGGSP+ GY +E+++ W ++ D
Sbjct: 13482 VNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKV-MDF 13540
Query: 674 CKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPF---VPLAVTSPPTLLTVDSVT 730
+ F +++G Y ++ A N G +P+ P P V PP + T
Sbjct: 13541 VTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRT 13600
Query: 731 DTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLI 790
++ + W PP + G + + GY++E C GS + W+ + +
Sbjct: 13601 ANSIFLTWDPPKNDGGSRIKGYIVERCPRGS------------------DKWVACGEP-V 13641
Query: 791 DKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYI 850
+TK +TGL RVKA+N GAS+P ++ I + E P+I + L
Sbjct: 13642 AETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLT 13701
Query: 851 RRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKN-QINIRNSETDTIIFIRKAERSHSGKY 909
+ G + L GKP P++TW K + ++ +I I N + + I ++RS +G Y
Sbjct: 13702 VKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTY 13761
Query: 910 DLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQ 969
++ TA +++ ++D+PGPP I DV E+ LTW PP+DDG + IT Y ++
Sbjct: 13762 IIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVE 13821
Query: 970 KADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1015
+ S W + T+ T+L+ EY FRV +ENM G+ E
Sbjct: 13822 RRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGE 13867
Score = 239 bits (610), Expect = 1e-62
Identities = 138/399 (34%), Positives = 201/399 (50%), Gaps = 21/399 (5%)
Query: 620 PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTF 679
P PP P VT V D ++W P DGGSPILGY +ERK++ W ++ L F
Sbjct: 21259 PGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIF 21318
Query: 680 EPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWR 739
+ + +G+AYE R+ A N G SKPS PS P + L PP ++T TVT++W
Sbjct: 21319 KSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWA 21378
Query: 740 PPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITG 799
P++ G + Y++E DLP W+ AN I + +FT++G
Sbjct: 21379 KPEYTGGFKITSYIVE------------------KRDLPNGRWLKANFSNILENEFTVSG 21420
Query: 800 LPTDAKIFVRVKAVNAAGA-SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVN 858
L DA RV A NAAGA S P S I ++ +E PKI++ K T I + GEA
Sbjct: 21421 LTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVILKAGEAFR 21480
Query: 859 LVIPFQGKPRPELTWKKDGAEIDKN-QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDK 917
L G+P P + W KDG E++ ++ I+ ++ T + + + R SG Y L
Sbjct: 21481 LEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPG 21540
Query: 918 FVETASIDIQIIDRPGPPQ-IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSM 976
+++++DRPGPP+ + + +V E L+W PP DDG A I Y +QK + +
Sbjct: 21541 GFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRL 21600
Query: 977 EWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1015
W V T +T+L+ GNEY FRV + N G+ E
Sbjct: 21601 AWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGE 21639
Score = 239 bits (610), Expect = 1e-62
Identities = 162/609 (26%), Positives = 285/609 (46%), Gaps = 58/609 (9%)
Query: 429 DLKPLKILTPLTDQTVNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIH 486
D+KP + +V +G+++ ++ IS WTK+GLP++++ R+ V +
Sbjct: 23231 DVKPA-----FSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLT 23285
Query: 487 KLVIANALTEDEGDYVFAPDAYNVTLPAKVHVI-----DPPK--IILDGLDADNTVTVIA 539
L I +D G Y A + ++ DPPK + D + A++
Sbjct: 23286 TLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAES------ 23339
Query: 540 GNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRT-----ESYPDSSTLVIDIAERDDS 594
I +S PP + I++ T + +TL + +
Sbjct: 23340 -------ITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTE 23392
Query: 595 GVYHINLKNEAGEAHASIKVKVV-----DFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGS 649
+ I +N G++ A +V P PP P T + D ++ W P +GGS
Sbjct: 23393 YQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGS 23452
Query: 650 PILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPS 709
P++GY +ERK++ S W ++N + +T F+ + + EG+ YE R++A N +G+ K S S
Sbjct: 23453 PVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNS 23512
Query: 710 RPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDE 769
+V PP V +T++W P + G + + GY++E
Sbjct: 23513 ECYVARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVE-------------- 23558
Query: 770 NGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGA-SEPKYYSQPI 828
DLP W+ A+ + +T+FT++GL D + RV A NAAGA S+P + PI
Sbjct: 23559 ----KRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPI 23614
Query: 829 LVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKN-QINI 887
K+ +E P+I + + T + GE L GKP P + W + EI+++ + I
Sbjct: 23615 TAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEI 23674
Query: 888 RNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWGE 946
+N++ ++ ++ A R G+Y L+ ++ ++++++DRPGPP+ V++ V E
Sbjct: 23675 KNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSE 23734
Query: 947 NVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVF 1006
+LTW+PP DG + I+ Y ++K + + W V S +T+L+ GNEY FR+
Sbjct: 23735 KCSLTWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIM 23794
Query: 1007 SENMCGLSE 1015
+ N G+ E
Sbjct: 23795 AVNKYGVGE 23803
Score = 239 bits (610), Expect = 1e-62
Identities = 171/602 (28%), Positives = 283/602 (47%), Gaps = 51/602 (8%)
Query: 436 LTPLTDQTVNL--GKEICLKCEISENIP--GKWTKNGLPVQESDRLKVVHKGRIHKLVIA 491
L+ + +T+++ G+ + L I+ P W G ++ES+R+ V ++ KL I
Sbjct: 29740 LSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIR 29799
Query: 492 NALTEDEGDYVFAPDAYNVTLPA----KVHVIDPP-----KIILDGLDADNTVTVIAGNK 542
D G+Y + NVT KV ++D P I +D +DA + +
Sbjct: 29800 ETTIRDTGEYTL--ELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPE 29857
Query: 543 LRLEIPISG-----EPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVY 597
L P+SG + W +++ + + + + + R G Y
Sbjct: 29858 LDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSY 29917
Query: 598 HINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIE 657
L++E E +SI++ P PP + +V D + W PP DGGS + GY +E
Sbjct: 29918 ---LQSEVIECRSSIRI-----PGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVE 29969
Query: 658 RKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAV 717
RK+ ++ RW+R+N T + + EG+ YE R+ A+NA G KPS PS+P V +
Sbjct: 29970 RKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDP 30029
Query: 718 TSPPTLLTVDSVTDTT---VTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAA 774
+PP VTDTT V++ W P+ G + + GY++E ++ D++
Sbjct: 30030 IAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIE--------MQKVDQH---- 30077
Query: 775 YDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEII 834
+W N ++T+T LP A+ RV A NA G EP + V E++
Sbjct: 30078 ------EWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEML 30131
Query: 835 EPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDT 894
E P + ++ R G + L IP +GKP P W K+G +I K + I SET T
Sbjct: 30132 EYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAM-IATSETHT 30190
Query: 895 IIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWGENVALTWT 953
+ I++A+R SG YDL ++ + I +++I P P+ ++ +D+ +V ++W
Sbjct: 30191 ELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVSWR 30250
Query: 954 PPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL 1013
PP DDG A I GY +++ + W+T+ TS + L EY+FRV +EN G+
Sbjct: 30251 PPADDGGADILGYILERREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGI 30310
Query: 1014 SE 1015
S+
Sbjct: 30311 SK 30312
Score = 238 bits (607), Expect = 2e-62
Identities = 169/578 (29%), Positives = 277/578 (47%), Gaps = 44/578 (7%)
Query: 464 WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVH--VIDP 521
W K+G+ ++E R +++ L + + + D G YV T V+ V+D
Sbjct: 25823 WAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDK 25882
Query: 522 P-----KIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTE 576
P + ++GL A+ + I K S I EG ++
Sbjct: 25883 PGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQM--- 25939
Query: 577 SYPDSSTLVIDIAERDDSGVYHINLKNE--AGEAHASIKVKVVD---FPDPPVAPTVTEV 631
+S V + + ++ ++ + N+ GE S+ +K +D P PP + +T V
Sbjct: 25940 ----TSCKVTKLLKGNEY-IFRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSV 25994
Query: 632 GDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYE 691
+ + W P DGGS I GY IER++K S RW+R+N + + + EG YE
Sbjct: 25995 TKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYE 26054
Query: 692 VRIFAVNAIGISKPSMPS---RPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAG 748
R++A NA G+S PS S R P+ + SPP+ + TT+T+ W P G A
Sbjct: 26055 YRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAP 26114
Query: 749 LDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFV 808
+ GY +EY K+SD+ DW + + L T++TI+GL T A+
Sbjct: 26115 ITGYTVEY--------KKSDDT----------DWKTSIQSLRG-TEYTISGLTTGAEYVF 26155
Query: 809 RVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPR 868
RVK+VN GAS+P S P + KE E P I +++T I + G + + +PF+G+P
Sbjct: 26156 RVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPV 26215
Query: 869 PELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQI 928
P + W K ++ + + + +++ T + I A R+ SGKY L ++ + ++ +++
Sbjct: 26216 PNVLWSKPDTDL-RTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKV 26274
Query: 929 IDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRT 988
+D PGPP + ++DV E+ L+W P++DG A + Y I+K + W +V + +R
Sbjct: 26275 LDTPGPPTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCNRL 26334
Query: 989 SATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVI 1026
S +T L G YYFRV EN G+ A TKE I
Sbjct: 26335 SYKVTNLQEGAIYYFRVSGENEFGVGIPAE-TKEGVKI 26371
Score = 236 bits (603), Expect = 7e-62
Identities = 153/533 (28%), Positives = 261/533 (48%), Gaps = 43/533 (8%)
Query: 518 VIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTES 577
++ PP+ LD D T+ + AG +RL +P+ G PPPK WS+ + + + G + +S
Sbjct: 19687 ILIPPEGELDA-DLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIG-LDIKS 19744
Query: 578 YPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCI 637
+ L + + D+G Y + L+N G+ +I VKV+D P PPV TV E+ D
Sbjct: 19745 TDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAY 19804
Query: 638 MNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAV 697
+ WEPP DGGSPI+ Y ++++ + W + + C +T+F + EG +Y R+FA
Sbjct: 19805 VTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTE-CSKTSFRVANLEEGKSYFFRVFAE 19863
Query: 698 NAIGISKPSMPSRPFVPLAVTSPPTL-LTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEY 756
N GI P +R V + T P + L V SV+ ++ ++ W+ P G + + GYV+++
Sbjct: 19864 NEYGIGDPG-ETRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDF 19922
Query: 757 CFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAA 816
++EN W K L +++ L + RV A N
Sbjct: 19923 L---------TEEN----------KWQRVMKSL--SLQYSAKDLTEGKEYTFRVSAENEN 19961
Query: 817 GASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKK- 875
G P + ++ ++ + P + + Y+ + L IP +GKP P ++WKK
Sbjct: 19962 GEGTPSEIT--VVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKG 20019
Query: 876 DGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPG-P 934
+ ++++ +S +T + + ++S +GKY + +K + +I I+++ +PG P
Sbjct: 20020 EDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKPGIP 20079
Query: 935 PQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITE 994
+K ++V E + L W PPKDDG + IT Y ++K D + +W T +T+ +T
Sbjct: 20080 TGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAVQKTTFRVTR 20139
Query: 995 LVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAP 1047
L G EY FRV +EN G+ E K ++AR FD +AP
Sbjct: 20140 LHEGMEYTFRVSAENKYGVGEG---LKSEPIVAR----------HPFDVPDAP 20179
Score = 236 bits (603), Expect = 7e-62
Identities = 185/698 (26%), Positives = 312/698 (44%), Gaps = 80/698 (11%)
Query: 364 EVSEDDANVKWFK----NGEEII-------PGPKSRYRIRVEGKKHILIIEGATKADAAE 412
+VS+ A++ W K G ++ P ++ I E K ++ G + +
Sbjct: 24223 DVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQ 24282
Query: 413 YSVMTTG--GQSSAKL--------SVDLKPLKILTPLTDQTVNLGKEICLKCEI----SE 458
+ V G+S ++ + ++P + P ++ G+++ ++ +
Sbjct: 24283 FRVKAYNEKGKSDPRVLGVPVIAKDLTIQP-SLKLPFNTYSIQAGEDLKIEIPVIGRPRP 24341
Query: 459 NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAP--DAYNVTLPAKV 516
NI W K+G P++++ R+ V L I +D G Y A T V
Sbjct: 24342 NI--SWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSV 24399
Query: 517 HVIDPP-----KIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSG 571
V++ P + D + AD V IS EPP + I+E
Sbjct: 24400 IVLEKPGPPVGPVRFDEVSADFVV-------------ISWEPPAYTGGCQISNYIVEKRD 24446
Query: 572 RIRTESYPDSSTLV---IDIAERDDSGVYHINL--KNEAGE-AHASIKVKVVDFP----D 621
T + S+T+ I I + Y + +N G+ A K +V +P
Sbjct: 24447 TTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEPG 24506
Query: 622 PPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEP 681
PP P VT + D ++ W P DGG+ I+GY +E+K+K S W++LN ++T F+
Sbjct: 24507 PPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKT 24566
Query: 682 KKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPP 741
+ EG+ YE ++ A N +GI KPS S FV PP +T VT++W+ P
Sbjct: 24567 TGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIVITRNNVTLKWKKP 24626
Query: 742 DHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLP 801
+ G + + GY++E DLP W+ A+ + +T+FT++GL
Sbjct: 24627 AYDGGSKITGYIVE------------------KKDLPDGRWMKASFTNVLETEFTVSGLV 24668
Query: 802 TDAKIFVRVKAVNAAG-ASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLV 860
D + RV A NAAG SEP S I ++ I+ P + K + GE L
Sbjct: 24669 EDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGETFVLE 24728
Query: 861 IPFQGKPRPELTWKKDGAEIDKN--QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKF 918
+GKP P++ W KDG E+++ ++ I+++ T + ++ R+ G+Y L++
Sbjct: 24729 ADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGG 24788
Query: 919 VETASIDIQIIDRPGPPQ-IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSME 977
++ I ++++DRPGPP+ +K+ V E L W PP DG A I+ Y I+K + +
Sbjct: 24789 TKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLS 24848
Query: 978 WFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1015
W V + +T+L+ GNEY FRV + N G+ E
Sbjct: 24849 WTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGE 24886
Score = 234 bits (596), Expect = 5e-61
Identities = 171/604 (28%), Positives = 285/604 (47%), Gaps = 46/604 (7%)
Query: 428 VDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVVHKGRIHK 487
+DLK +LT T+ L E ++ + + K+ + S R+K+ + K
Sbjct: 18203 LDLKLSGVLTVKAGDTIRL--EAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSK 18260
Query: 488 LVIANALTEDEGDYVFAPD--AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRL 545
+ A D G YV A + A V+V+D P G + + ++ ++
Sbjct: 18261 FSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKP-----GPVRNLKIVDVSSDRCT- 18314
Query: 546 EIPISGEPPPKAMWSRGDKAIMEG--SGRIRTESYPDS----STLVIDIAERDDSGVYHI 599
+ +PP I+E + R+ +Y + T V + E ++ ++ +
Sbjct: 18315 ---VCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEY-IFRV 18370
Query: 600 NLKNEAG-----EAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGY 654
+N+ G E+ I D P P P VT+V + + W PP YDGG I GY
Sbjct: 18371 RAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGY 18430
Query: 655 FIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV- 713
F+E+K+K S+RW+ +N E + + ++ Y+ R+ A N IGI +PS+PSRP V
Sbjct: 18431 FLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVA 18490
Query: 714 --PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENG 771
P+ PPT V T ++T+ W P + G A + GYV+E K +D +
Sbjct: 18491 KDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEM------RPKIADAS- 18543
Query: 772 EAAYDLPAEDWIVANKDL-IDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILV 830
P E W N + + +FT+T L + + RV A N G P + I
Sbjct: 18544 ------PDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKP 18597
Query: 831 KEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAE--IDKNQINIR 888
KEI+EPP+I + +++ I R G + L +G+P P++TW+K G + + K Q+++
Sbjct: 18598 KEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDL- 18656
Query: 889 NSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENV 948
+T + I + R SGKY L + + ++++++D PGP +K+ DV +
Sbjct: 18657 -VDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSC 18715
Query: 949 ALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSE 1008
++W PP++DG + +T Y ++K + W TV +TS +T LV GNEYYFRV +
Sbjct: 18716 HVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAV 18775
Query: 1009 NMCG 1012
N G
Sbjct: 18776 NEYG 18779
Score = 233 bits (594), Expect = 8e-61
Identities = 202/725 (27%), Positives = 321/725 (44%), Gaps = 83/725 (11%)
Query: 332 STELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKW----FKNGEEIIP---- 383
S L +REP I V ++ ED +E++ EV+++ + W + G EII
Sbjct: 16705 SEALVIREP-ITVPERPED--------LEVK-EVTKNTVTLTWNPPKYDGGSEIINYVLE 16754
Query: 384 ----GPKSRYRIRVEGK-KHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTP 438
G + +++ + ++G + D EY V K S KP+
Sbjct: 16755 SRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDE 16814
Query: 439 LTDQTVNLGKEICLKCEISE------NIPGK------WTKNGLPVQESDRLKVVHKGRIH 486
L T++L L + E GK W K+ V E DR +
Sbjct: 16815 LAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATL 16874
Query: 487 KLVIANALTEDEGDYVFAPDAYNVTLPAK----VHVIDPPKIILDGLDADNTVTVIAGNK 542
L A D G Y + N T K V+V+D P + + D
Sbjct: 16875 ALEKIKAKRSDSGKYCVVVE--NSTGSRKGFCQVNVVDRPGPPVGPVSFDEVT------- 16925
Query: 543 LRLEIPISGEPPPKAMWSRGDKAIMEGSGRIR------TESYPDSSTLVIDIAERDDSGV 596
+ + IS +PP S+ I+E + T + ++ V + E D +
Sbjct: 16926 -KDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDY-I 16983
Query: 597 YHINLKNEAG--EAHASIKVKVVD---FPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPI 651
+ I+ +N G + S +K D PD P P VTEV D ++ W P +DGG PI
Sbjct: 16984 FRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKP-HDGGKPI 17042
Query: 652 LGYFIERKKKQSSRWMRLNFD-LCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSR 710
Y +E+++ S RW R+ D + T F ++EG YE R+ A N IGI PS PS+
Sbjct: 17043 TNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSK 17102
Query: 711 PFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQS 767
P P+A SPP T +V + W+PP H G + + GY++EY K
Sbjct: 17103 PVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEY-------QKVG 17155
Query: 768 DENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQP 827
DE A P + +TK+ +TGL RV AVNAAG S+P + +P
Sbjct: 17156 DEEWRRANHTP---------ESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEP 17206
Query: 828 ILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINI 887
+LVK+ +EPP++ + ++ + +VG+ + L +G P P++TWKK+ + + I
Sbjct: 17207 VLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAP-TKARI 17265
Query: 888 RNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGEN 947
+ + + IR A G Y L V+ +T S+ + ++D+PGPP+ +++ ++ ++
Sbjct: 17266 DVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDS 17325
Query: 948 VALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFS 1007
LTW P DDG + IT Y +++ D S +W + + S L GN+Y FRV +
Sbjct: 17326 CYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAA 17385
Query: 1008 ENMCG 1012
EN G
Sbjct: 17386 ENQYG 17390
Score = 233 bits (593), Expect = 1e-60
Identities = 172/611 (28%), Positives = 288/611 (47%), Gaps = 45/611 (7%)
Query: 241 LKRMRREEKKSAAFA-------KILDPAYQVDKGGR--VRFVVELADPKLEVKWYKNGQE 291
L R E KSAA +I++P ++ + V F ++ + +KW KNG+E
Sbjct: 12713 LTNHRGENVKSAANLIVEEEDLRIVEPLKDIETMEKKSVTFWCKVNRLNVTLKWTKNGEE 12772
Query: 292 IRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDT 351
+ + + + +L I +C D+ EY VTAG +K EL + E P + LED
Sbjct: 12773 VPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYIVTAGQDKSVAELLIIEAPTEFVEHLEDQ 12832
Query: 352 TAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAA 411
T + C++S + ANVKW++NG EI G K Y+ +G H LII+ D
Sbjct: 12833 TVTEFDDAVFSCQLSREKANVKWYRNGREIKEGKK--YKFEKDGSIHRLIIKDCRLDDEC 12890
Query: 412 EYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLP 470
EY+ +S A+L V+ P++I+ P D G ++ E++ + + +W +N +
Sbjct: 12891 EYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQWLRNNMV 12950
Query: 471 VQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLD 530
V + D+ +++ +G+IH+L I + D+G+Y F A + AK+ + PKI
Sbjct: 12951 VVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFI--AKDKEARAKLELAAAPKI----KT 13004
Query: 531 ADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAE 590
AD + V G L + +P P +A W + ++ + + ++ + ++ I A+
Sbjct: 13005 ADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKT----IDTTAEQTSFRILEAK 13060
Query: 591 RDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSP 650
+ D G Y I L+N+ G+A I +KV+D P P VTE D + WE P DGGS
Sbjct: 13061 KGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSK 13120
Query: 651 ILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIE-GVAYEVRIFAVNAIGISKPSMPS 709
I+GY +ER+ + W+ L D + F + + GV Y R+ A N +G +P
Sbjct: 13121 IIGYVVERRDIKRKTWV-LATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETD 13179
Query: 710 RPFVPLA---VTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQ 766
P + V PP +T+ V V++ W PP++ G A + YV+E TS +
Sbjct: 13180 NPVEARSKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIE--LRDKTSIR- 13236
Query: 767 SDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQ 826
+ A + AED D+++ +++ RV+A N G +P +
Sbjct: 13237 ----WDTAMTVRAEDLSATVTDVVEGQEYSF-----------RVRAQNRIGVGKPSAATP 13281
Query: 827 PILVKEIIEPP 837
+ V + IE P
Sbjct: 13282 FVKVADPIERP 13292
Score = 232 bits (592), Expect = 1e-60
Identities = 158/525 (30%), Positives = 252/525 (48%), Gaps = 40/525 (7%)
Query: 520 DPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWS---RGDKAIMEGSGRI--- 573
+ P++ +D + A + + AG+++R+ I G P PK+ W + KA+ +G I
Sbjct: 15806 EEPEVFID-IGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPED 15864
Query: 574 -RTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVG 632
+ E+ +SS ++I +R +G Y I KN+AG+ A+ +VKV+D P PP V+++
Sbjct: 15865 AQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDIT 15924
Query: 633 DDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEV 692
C ++W+ P DGG I GY IE++ W ++N D C TTF ++ Y
Sbjct: 15925 RGSCRLSWKMPDDDGGDRIKGYVIEKRTIDGKAWTKVNPD-CGSTTFVVPDLLSEQQYFF 15983
Query: 693 RIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGL 749
R+ A N GI P + P+ PP L + +T TV + W+PP + G + +
Sbjct: 15984 RVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPV 16043
Query: 750 DGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVR 809
Y++E T K+ E W NK +++ +FT+ L + R
Sbjct: 16044 THYIVECLAWDPTGTKK-------------EAWRQCNKRDVEELQFTVEDLVEGGEYEFR 16090
Query: 810 VKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRP 869
VKAVNAAG S+P P + PP I LK+ G VN+V +G P P
Sbjct: 16091 VKAVNAAGVSKPSATVGPCDCQRPDMPPSI----DLKEFMEVEEGTNVNIVAKIKGVPFP 16146
Query: 870 ELTW------KKDGAE---IDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVE 920
LTW K D E D + + +T T++ I ++ RS +G Y + +
Sbjct: 16147 TLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLV-IPQSRRSDTGLYTITAVNNLGTA 16205
Query: 921 TASIDIQIIDRPGPP-QIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF 979
+ + + ++ RPGPP +K E V + + L+W PPKDDG + IT Y I+K + W
Sbjct: 16206 SKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWV 16265
Query: 980 TVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESA 1024
V + TI +L+ G+EY FR+ ++N G+ E E+A
Sbjct: 16266 HVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETA 16310
Score = 232 bits (591), Expect = 2e-60
Identities = 174/651 (26%), Positives = 304/651 (46%), Gaps = 60/651 (9%)
Query: 386 KSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVN 445
K++Y+ R + + I + +D +++ LSV +K L TV
Sbjct: 19259 KAQYQFRAIARTAVNISPPSEPSDPV--TILAENVPPRIDLSVAMKSLL--------TVK 19308
Query: 446 LGKEICLKCEI-SENIPG-KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF 503
G +CL + + +P W K+G ++ ++ +K+ + + L + + +D GDY
Sbjct: 19309 AGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTI 19368
Query: 504 APDAYNVTLPA--KVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSR 561
+ + + A K+ V+D P G A + + ++ L S EPP + S
Sbjct: 19369 TAENSSGSKSATIKLKVLDKP-----GPPASVKINKMYSDRAML----SWEPPLEDGGSE 19419
Query: 562 GDKAIMEGSGRIRTESYPDSSTLVI---DIAERDDSGVYHINL--KNEAGEA-----HAS 611
I++ R S+T+ I + + + Y + +N+ G +
Sbjct: 19420 ITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPA 19479
Query: 612 IKVKVVDFP---DPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMR 668
I D P DPPV +T+ D ++W+PPA DGGSPI GY +E+++ Q+ W +
Sbjct: 19480 IAKNPYDPPGRCDPPVISNITK---DHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTK 19536
Query: 669 LNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLT 725
+N E T + + EG YE R+ A+N G KPS S+ P PP
Sbjct: 19537 VNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPK 19596
Query: 726 VDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVA 785
V T ++V++ W P + G + + GY++E K++D + +LP
Sbjct: 19597 VYDTTRSSVSLSWGKPAYDGGSPIIGYLVE--------VKRADSDNWVRCNLPQN----- 19643
Query: 786 NKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHL 845
+ KT+F +TGL D + RV AVN G S+P K+I+ PP+ + L
Sbjct: 19644 ----LQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADL 19699
Query: 846 KQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI-DKNQINIRNSETDTIIFIRKAERS 904
++T I R G + L +P +G+P P++TW K + D+ ++I++++ DT + +
Sbjct: 19700 RKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKY 19759
Query: 905 HSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAIT 964
+GKY L ++ + +I ++++D PGPP V ++++ ++ +TW PP DG + I
Sbjct: 19760 DAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPII 19819
Query: 965 GYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1015
Y +QK D + W TV +TS + L G Y+FRVF+EN G+ +
Sbjct: 19820 NYVVQKRDAERKSWSTVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGD 19870
Score = 229 bits (585), Expect = 9e-60
Identities = 149/513 (29%), Positives = 245/513 (47%), Gaps = 28/513 (5%)
Query: 506 DAYNVTLPAK-VHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDK 564
D+ VT K V + P++ +D + T V AG +RL I G P P A+WS+ D
Sbjct: 28338 DSCEVTGTIKAVDRLTAPELDIDA-NFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDS 28396
Query: 565 AIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPV 624
+ + T+S+ STL ++ R+D+G Y + ++N +G + VKV+D P PP
Sbjct: 28397 NLSLRADIHTTDSF---STLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGPPG 28453
Query: 625 APTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKM 684
T +V + W+ P DGG+ I Y +E+++ W ++ + C F+ +
Sbjct: 28454 PITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVIS-EKCTRQIFKVNDL 28512
Query: 685 IEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHI 744
EGV Y R+ AVN G+ +P P V +PP L V + ++ + W PDH
Sbjct: 28513 AEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHD 28572
Query: 745 GAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDA 804
G + + GY+LE +GS + W+ A + FT+ L
Sbjct: 28573 GGSRITGYLLEMRQKGS------------------DFWVEAGH--TKQLTFTVERLVEKT 28612
Query: 805 KIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQ 864
+ RVKA N AG SEP+ +++KE P + Q + G + +P
Sbjct: 28613 EYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPIS 28672
Query: 865 GKPRPELTWKKDGAEI-DKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETAS 923
G+P P++TWK + + + ++++I ++ T + ++ + R SG+Y L ++ V+T S
Sbjct: 28673 GRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFS 28732
Query: 924 IDIQIIDRPGP-PQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVI 982
+ + +I RPGP +++ V E+ L+W PKD G IT Y ++K + + W V
Sbjct: 28733 VTVVVIGRPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVN 28792
Query: 983 EHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1015
RT +T L EY FRV SEN G+S+
Sbjct: 28793 SSVKRTQIKVTHLTKYMEYSFRVSSENRFGVSK 28825
Score = 229 bits (584), Expect = 1e-59
Identities = 159/586 (27%), Positives = 270/586 (46%), Gaps = 42/586 (7%)
Query: 465 TKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKI 524
+++G+P++ + R + + ++T D G Y + T A ++++
Sbjct: 26511 SRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIV----- 26565
Query: 525 ILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIM---EGSGRIRTESYPDS 581
+LD T V+ + + + EPP S+ I+ E S + TE
Sbjct: 26566 VLDR-PGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATV 26624
Query: 582 STLVIDIAERDDSGVYHINLKNE--------AGEAHASIKVKVVDFPDPPVAPTVTEVGD 633
+ ++ + + Y +K E A ++K+ P PP P VT V
Sbjct: 26625 ARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTT-PGPPSTPWVTNVTR 26683
Query: 634 DWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVR 693
+ + W P +GGS ++GY +E K + S W + N + + T F+ + G+ YE R
Sbjct: 26684 ESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFR 26743
Query: 694 IFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYV 753
++A NA G+ KPS PS P + + PP + + ++ +V++ W+ P G + + GY+
Sbjct: 26744 VYAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYI 26803
Query: 754 LEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAV 813
+E DLP W A+ + +T+F I+GL +++ RV A
Sbjct: 26804 VE------------------RRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFAR 26845
Query: 814 NAAGA-SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELT 872
NA G+ S P PI + P I +P + R G +V L GKP P +
Sbjct: 26846 NAVGSISNPSEVVGPITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIE 26905
Query: 873 WKKDGAEIDKNQINIRNSETD-TIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDR 931
W KD E+ N + + TD I I+ A+R +SG Y+L+++ +A+I +QI+D+
Sbjct: 26906 WYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDK 26965
Query: 932 PGPP-QIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSA 990
PGPP ++ + V E + L W PP DDG A IT Y ++K + + W V EH
Sbjct: 26966 PGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVSEHLEECII 27025
Query: 991 TITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNP 1036
T T+++ GNEY FRV + N G+ E + +V+A++ + P
Sbjct: 27026 TTTKIIKGNEYIFRVRAVNKYGIGEP---LESDSVVAKNAFVTPGP 27068
Score = 228 bits (581), Expect = 3e-59
Identities = 172/638 (26%), Positives = 274/638 (42%), Gaps = 44/638 (6%)
Query: 394 EGKKHILIIEGATKADAAEYSVMTTGGQSSAKL-SVDLKPLKILTPLTDQTVNLGKEICL 452
EGK++ + + S +T + +DLK L L L + N +I +
Sbjct: 19947 EGKEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPI 20006
Query: 453 KCEISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTL 512
K + + ++ W K P+ R+ V L++ + D G Y T
Sbjct: 20007 KGKPAPSV--SWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTK 20064
Query: 513 PA--KVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGS 570
+ V+ P I + D VT A + + PP S I+E
Sbjct: 20065 EGTISIKVVGKPGIPTGPIKFDE-VTAEA-------MTLKWAPPKDDGGSEITNYILEKR 20116
Query: 571 GRIRTE-----SYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVV-----DFP 620
+ + S +T + + ++ +N+ G +V D P
Sbjct: 20117 DSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVP 20176
Query: 621 DPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFE 680
D P P + +V D + W P GGSPI GY +E K++ S W R N + F+
Sbjct: 20177 DAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFK 20236
Query: 681 PKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRP 740
+ EG+ YE R+ A+N G+ KPS+PS P V L PP V ++T +VT+ W
Sbjct: 20237 VTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTE 20296
Query: 741 PDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGL 800
P + G L GY++E DLP++ W+ AN + + FT+T L
Sbjct: 20297 PKYDGGHKLTGYIVE------------------KRDLPSKSWMKANHVNVPECAFTVTDL 20338
Query: 801 PTDAKIFVRVKAVNAAGA-SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNL 859
K R++A N AGA S P ++ I+ K+ E P I + +K + G+ + L
Sbjct: 20339 VEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVL 20398
Query: 860 -VIPFQGKPRPELTWKKDGAEIDKNQI-NIRNSETDTIIFIRKAERSHSGKYDLQVKVDK 917
I GKP P+ +W K G +I + I I ++ T +++ I+ A R +G+Y +
Sbjct: 20399 NAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPF 20458
Query: 918 FVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSME 977
+ + + ++D PGPP V+I +V E LTWTPP +DG + I Y ++K + +
Sbjct: 20459 GTKVEHVKVTVLDVPGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLL 20518
Query: 978 WFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1015
W V E T+L+ GNEY FRV + N G E
Sbjct: 20519 WTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYGKGE 20556
Score = 227 bits (579), Expect = 4e-59
Identities = 156/571 (27%), Positives = 260/571 (45%), Gaps = 50/571 (8%)
Query: 464 WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF--APDAYNVTLPAKVHVIDP 521
W K+G ++E+ R+ V + L I A ED G Y + A ++T+P + V+D
Sbjct: 25428 WRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDR 25487
Query: 522 P----KIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTES 577
P I +D + D+ I IS PP + I+E T
Sbjct: 25488 PGPPGPIRIDEVSCDS-------------ITISWNPPEYDGGCQISNYIVEKKETTSTTW 25534
Query: 578 YPDSSTLV---IDIAERDDSGVYHINL-------KNEAGEAHASIKVKVVDFPDPPVAPT 627
+ S + I I Y + K+ E+ A + P PP P
Sbjct: 25535 HIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPK 25594
Query: 628 VTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEG 687
V ++ W+ P DGGS ++GY +E K++ S W + N L +T + + EG
Sbjct: 25595 VVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIADTQMKVSGLDEG 25654
Query: 688 VAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAA 747
+ YE R++A N GI K S P PP V ++T +V+++W P + G A
Sbjct: 25655 LMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGA 25714
Query: 748 GLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIF 807
+ GY++E +LP W+ N I +T F +T L D +
Sbjct: 25715 KITGYIVE------------------RRELPDGRWLKCNYTNIQETYFEVTELTEDQRYE 25756
Query: 808 VRVKAVNAA-GASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGK 866
RV A NAA SEP + PI+VK+ +EPP++ + + + + GE + + G+
Sbjct: 25757 FRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGR 25816
Query: 867 PRPELTWKKDGAEIDKN-QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASID 925
P P ++W KDG EI++ + I +++ T++ ++ R +G+Y L +K + +++
Sbjct: 25817 PLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVN 25876
Query: 926 IQIIDRPGPPQ-IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEH 984
+++D+PGPP ++I + E +L+W P++DG A I Y ++K + + W
Sbjct: 25877 CKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGE 25936
Query: 985 YHRTSATITELVIGNEYYFRVFSENMCGLSE 1015
TS +T+L+ GNEY FRV N G+ E
Sbjct: 25937 LQMTSCKVTKLLKGNEYIFRVTGVNKYGVGE 25967
Score = 226 bits (575), Expect = 1e-58
Identities = 154/509 (30%), Positives = 238/509 (46%), Gaps = 33/509 (6%)
Query: 519 IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESY 578
++PP++ILD A + G+ LRL I G P PK W + D+ + + R +
Sbjct: 17213 LEPPELILDANMAREQ-HIKVGDTLRLSAIIKGVPFPKVTWKKEDR---DAPTKARIDVT 17268
Query: 579 PDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIM 638
P S L I A +D G+Y + ++N AG S+KV V+D P PP V+E+ D C +
Sbjct: 17269 PVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYL 17328
Query: 639 NWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVN 698
W+ P DGGS I Y +ER+ S++W L+ K++ F K + EG Y R+ A N
Sbjct: 17329 TWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHF-AKHLNEGNQYLFRVAAEN 17387
Query: 699 AIG---ISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLE 755
G + P + PL PP L V T V++ W PD G + + GY++E
Sbjct: 17388 QYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVE 17447
Query: 756 YCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNA 815
Y EG+ +DWI + + +TGL RVKA N
Sbjct: 17448 YQEEGT------------------QDWI--KFKTVTNLECVVTGLQQGKTYRFRVKAENI 17487
Query: 816 AGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKK 875
G P + PI +E + PP + + L + + + G V +G P P W
Sbjct: 17488 VGLGLPD-TTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTT 17546
Query: 876 DGAEIDKNQ-INIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGP 934
DG+EI ++ + +++ I+ R +G+Y + V +T ++ + ++D PGP
Sbjct: 17547 DGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGP 17606
Query: 935 PQ-IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATIT 993
P + I DV E++ ++W PPKDDG + + Y ++K D + W V +T I
Sbjct: 17607 PTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIP 17666
Query: 994 ELVIGNEYYFRVFSENMCGLSE--DATMT 1020
L G EY FRV +EN G+ D+T T
Sbjct: 17667 HLQKGCEYVFRVRAENKIGVGPPLDSTPT 17695
Score = 224 bits (572), Expect = 3e-58
Identities = 142/494 (28%), Positives = 240/494 (48%), Gaps = 29/494 (5%)
Query: 529 LDAD--NTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVI 586
LDA+ T+ V AG +R+ +PI G P P+ W++ + + + TES+ + L+I
Sbjct: 20778 LDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESF---TLLII 20834
Query: 587 DIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYD 646
R D+G + + ++N AG+ + V+V+D P P + T++ D ++W+ P D
Sbjct: 20835 PECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLID 20894
Query: 647 GGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPS 706
GGS I Y +E+++ + C + T++ + EG Y R+ A N GI +P+
Sbjct: 20895 GGSRITNYIVEKREATRKSYSTATTK-CHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPT 20953
Query: 707 MPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQ 766
+ P SPP L + +T +TV++ W P H G + + GYV+E +GS
Sbjct: 20954 ETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGS----- 21008
Query: 767 SDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQ 826
+ W + + + + L + +V AVN+AG S P+ S+
Sbjct: 21009 -------------DQW--THITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPR-ESR 21052
Query: 827 PILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ-I 885
P++VKE P++ + ++ I + G+ + + IP G+P+P +TWKK + + Q +
Sbjct: 21053 PVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRV 21112
Query: 886 NIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVW 944
N + T TI+ I + RS SG Y L + I IQ+ D PGPP +K ++V
Sbjct: 21113 NFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVS 21172
Query: 945 GENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFR 1004
+ V +W PP++DG I+ Y ++ S W + RT+ T L G EY FR
Sbjct: 21173 SDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIRTTYKATRLTTGLEYQFR 21232
Query: 1005 VFSENMCGLSEDAT 1018
V ++N G+ T
Sbjct: 21233 VKAQNRYGVGPGIT 21246
Score = 224 bits (570), Expect = 5e-58
Identities = 165/572 (28%), Positives = 264/572 (46%), Gaps = 51/572 (8%)
Query: 464 WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV--FAPDAYNVTLPAKVHVIDP 521
W K+ +P++++ R+ L I +A ED G YV A V V+D
Sbjct: 22181 WHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDK 22240
Query: 522 P-----KIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTE 576
P + +D + AD+ I +S PP S + I+E T
Sbjct: 22241 PGPPTGPVKMDEVTADS-------------ITLSWGPPKYDGGSSINNYIVEKRDTSTTT 22287
Query: 577 SYPDSSTLVIDI--AERDDSGV---YHINLKNEAGEA-HASIKVKVVDF----PDPPVAP 626
S+T+ A R +G + I +N G++ + + + V + P PP P
Sbjct: 22288 WQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTP 22347
Query: 627 TVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIE 686
VT D + W P DGGS ++GY +ERK++ S W++LN +T F+ + E
Sbjct: 22348 VVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEE 22407
Query: 687 GVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGA 746
GV YE R+ A N +GI KPS S +V PP VT +VT++W+ P + G
Sbjct: 22408 GVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGG 22467
Query: 747 AGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKI 806
+ + GY++E +LP W+ A+ I T F +TGL D +
Sbjct: 22468 SKITGYIVE------------------KKELPEGRWMKASFTNIIDTHFEVTGLVEDHRY 22509
Query: 807 FVRVKAVNAAGA-SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQG 865
RV A NAAG SEP + I ++ ++PP+I + K T + GE+ + G
Sbjct: 22510 EFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYG 22569
Query: 866 KPRPELTWKKDGAEIDKN-QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASI 924
KP P + W K E+ ++ I++++ T + ++ A R SG Y L+ K + ++
Sbjct: 22570 KPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTV 22629
Query: 925 DIQIIDRPGPPQ-IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIE 983
+++++DRPGPP+ V I V E L W PP DG + I Y +++ + + W V
Sbjct: 22630 NVKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDA 22689
Query: 984 HYHRTSATITELVIGNEYYFRVFSENMCGLSE 1015
+ S +T+L+ GNEY FR+ + N G+ E
Sbjct: 22690 NVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGE 22721
Score = 220 bits (560), Expect = 7e-57
Identities = 161/544 (29%), Positives = 248/544 (45%), Gaps = 66/544 (12%)
Query: 520 DPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYP 579
+ P+I LD + +TV AG K+ L ++G+P PK W++ D I++ RI E+ P
Sbjct: 13686 EAPEIFLD-VKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADM-ILKQDKRITIENVP 13743
Query: 580 DSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMN 639
ST+ I ++R D+G Y I N G A A ++V V+D P PP A +T+V ++ C++
Sbjct: 13744 KKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLT 13803
Query: 640 WEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNA 699
W PP DGGS I Y +ER+ S W +L+ K+T F+ K+I Y R+ A N
Sbjct: 13804 WNPPRDDGGSKITNYVVERRATDSEVWHKLS-STVKDTNFKATKLIPNKEYIFRVAAENM 13862
Query: 700 IGISKP--SMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 757
G+ +P + P PPT L +T VT+ W PD G + + GY +E
Sbjct: 13863 YGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVE-- 13920
Query: 758 FEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAG 817
D + W+ NK + T + + GL K RV A N AG
Sbjct: 13921 ----------------RLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAG 13964
Query: 818 ASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKK-- 875
+P ++PIL+K+ I+PP +K GK L W K
Sbjct: 13965 PGKPSKSTEPILIKDPIDPPWPPGKPTVKDV----------------GKTSVRLNWTKPE 14008
Query: 876 --DGAEIDKNQINIRNSETDTIIFIRKAE-----------RSHSGKYDLQVK-VDKFVET 921
GA+I+ I + + TD ++R AE +Y +V+ V+K E+
Sbjct: 14009 HDGGAKIESYVIEMLKTGTDE--WVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGES 14066
Query: 922 ASID-------IQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKK 974
+ + + P PP+ +++ ++ L WT P+ DG + IT Y ++K D +
Sbjct: 14067 EPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVR 14126
Query: 975 SMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYK 1034
W TV T T+T L G+ Y FRV +EN G S+ + E +V+A+D
Sbjct: 14127 RKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEI--EDSVLAKDTFTTP 14184
Query: 1035 NPVY 1038
P Y
Sbjct: 14185 GPPY 14188
Score = 219 bits (559), Expect = 9e-57
Identities = 174/636 (27%), Positives = 290/636 (45%), Gaps = 67/636 (10%)
Query: 428 VDLKPLKILTPLTDQTV-NLGKEICLKCEISENIPG--KWTKNGLPVQESDRLKVVHKGR 484
V+ +K+ D + G+ L+ ++S P +W+K+G ++ + +L++
Sbjct: 21456 VEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADF 21515
Query: 485 IHKLVIANALTEDEGDYV--------FAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVT 536
LV ++ D G Y FA +NV V+D P + VT
Sbjct: 21516 STNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVK------VLDRP----GPPEGPLAVT 21565
Query: 537 VIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIR-----TESYPDSSTLVIDIAER 591
+ K L S PP ++ D I++ R S + L + +
Sbjct: 21566 EVTSEKCVL----SWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLK 21621
Query: 592 DDSGVYHINLKNEAG-----EAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYD 646
+ ++ + N+ G E+ + V PDPP P VT + D ++ W P D
Sbjct: 21622 GNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSD 21681
Query: 647 GGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPS 706
GGS I+ Y +ER+ K RW++ N + ++ + EG YE RI A NA GIS PS
Sbjct: 21682 GGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPS 21741
Query: 707 MPSRPFVPLAVT----SPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGST 762
P+ PF T PP V + +++++ W P + G + + GY++E
Sbjct: 21742 -PTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIA----- 21795
Query: 763 SAKQSDENGEAAYDLPAED-W-IVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASE 820
LP ED W IV + T +TITGL + + +R+ A+N+ G E
Sbjct: 21796 --------------LPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGE 21841
Query: 821 PKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKD-GAE 879
P ++ + PP+I + L++ R + L +P +G+P PE+ W +D G
Sbjct: 21842 PALVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGES 21901
Query: 880 IDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVK 939
+DK +I ++ + T++ + R SGKY L V+ ++A ++++++D PGPPQ +K
Sbjct: 21902 LDK--ASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLK 21959
Query: 940 IEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGN 999
+++V +V LTW PP DG + I Y ++K + + TV + H+TS + +L G
Sbjct: 21960 VKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGC 22019
Query: 1000 EYYFRVFSENMCGL---SEDATMTKESAVIARDGKI 1032
YYFRV +EN G+ +E A K S GKI
Sbjct: 22020 SYYFRVLAENEYGIGLPAETAESVKASERPLPPGKI 22055
Score = 219 bits (557), Expect = 2e-56
Identities = 163/601 (27%), Positives = 258/601 (42%), Gaps = 40/601 (6%)
Query: 430 LKPLKILTPLTDQTVNLGKEICLKCEI--SENIPGKWTKNGLPVQESDRLKVVHKGRIHK 487
L P KIL P T+ GK++ ++ + + KW K V S L V
Sbjct: 18897 LLPPKILMP-EQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSI 18955
Query: 488 LVIANALTEDEGDYVFAPDAYNVTLPAKVHVI-----DPPKIILDGLDADNTVTVIAGNK 542
L+I + +D G Y + + T K+ V+ PP+ D D D
Sbjct: 18956 LIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADAC-----S 19010
Query: 543 LRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLK 602
L IP+ + + G S +S V + + ++ + +
Sbjct: 19011 LSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEY-IFRVRAE 19069
Query: 603 NEAGEAHASIKVKVV-----DFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIE 657
N G + K+V P P VT+V D + W+ P DGGSPI+GY IE
Sbjct: 19070 NRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIE 19129
Query: 658 RKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAV 717
RK++ S W++ N L + T + ++EG+ Y RI+A+N G S PS P+
Sbjct: 19130 RKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMP 19189
Query: 718 TSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDL 777
PP V VT +TV++ W P H G + + GY +E C L
Sbjct: 19190 VDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEAC------------------KL 19231
Query: 778 PAEDWIVAN--KDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIE 835
P + W+ N I + ++T TGL A+ R A A S P S P+ +
Sbjct: 19232 PGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENV 19291
Query: 836 PPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ-INIRNSETDT 894
PP+I + +K + G V L GKP P ++WKKDG + + I +
Sbjct: 19292 PPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLC 19351
Query: 895 IIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTP 954
+ + R SG Y + + ++A+I ++++D+PGPP VKI ++ + L+W P
Sbjct: 19352 TLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEP 19411
Query: 955 PKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLS 1014
P +DG + IT Y + K + W V TS ++ +L+ G+EY FR+ +EN G+
Sbjct: 19412 PLEDGGSEITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVG 19471
Query: 1015 E 1015
+
Sbjct: 19472 D 19472
Score = 219 bits (557), Expect = 2e-56
Identities = 151/565 (26%), Positives = 257/565 (45%), Gaps = 42/565 (7%)
Query: 464 WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPD--AYNVTLPAKVHVIDP 521
W K+GLP++ES+ ++ L I NA E G Y D + +P V + P
Sbjct: 27597 WLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGP 27656
Query: 522 PK-----IILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTE 576
P I D + AD+ + L ++P +S + + + ++
Sbjct: 27657 PSKPKGPIRFDEIKADSVI-------LSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCS 27709
Query: 577 SYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVD-----FPDPPVAPTVTEV 631
S ++ V ++ +D + + +N G + + +V P PP P + V
Sbjct: 27710 SVARTTFKVPNLV-KDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNV 27768
Query: 632 GDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYE 691
D + W+ P YDGGS + G+ +E+K++ S W ++N + ++EG+ Y+
Sbjct: 27769 TSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQ 27828
Query: 692 VRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDG 751
R++A N+ G+S PS PS+ + ++ PP VT T+T++W PP G + + G
Sbjct: 27829 FRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVG 27888
Query: 752 YVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVK 811
Y +E +Q +E W+ N + + ++T+TGL + R+
Sbjct: 27889 YSIE--------KRQGNER-----------WVRCNFTDVSECQYTVTGLSPGDRYEFRII 27929
Query: 812 AVNAAGA-SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPE 870
A NA G S P S I+ ++ PP + I + GE++ + QG+P P
Sbjct: 27930 ARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPR 27989
Query: 871 LTWKKDGAEIDKN-QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQII 929
+TW KDG EI+K + I + T +F+R A R H G Y ++ K A I +++
Sbjct: 27990 VTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 28049
Query: 930 DRPGP-PQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRT 988
D PG ++ ++ GE + L W P +DG A IT Y I+K + + W + +
Sbjct: 28050 DTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQ 28109
Query: 989 SATITELVIGNEYYFRVFSENMCGL 1013
S T +L+ GNEY FRV + N G+
Sbjct: 28110 SYTAIKLINGNEYQFRVSAVNKFGV 28134
Score = 216 bits (551), Expect = 8e-56
Identities = 161/592 (27%), Positives = 267/592 (45%), Gaps = 52/592 (8%)
Query: 463 KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNV----TLPAKVHV 518
+W K + + RL++ L + +A+ D G+Y+ A NV ++ V V
Sbjct: 22576 QWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILK--AKNVAGERSVTVNVKV 22633
Query: 519 IDPP-----KIILDGLDADNTVTVIA-----GNKLRLEIPISGEPPPKAMWSRGDKAIME 568
+D P +++ G+ A+ G + + + +W+ D +
Sbjct: 22634 LDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQT 22693
Query: 569 GSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTV 628
S ++ + T I + G E E+ + PD P AP V
Sbjct: 22694 LSCKVTKLLEGNEYTFRIMAVNKYGVG--------EPLESEPVVAKNPFVVPDAPKAPEV 22745
Query: 629 TEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGV 688
T V D I+ WE PA DGGS ILGY +E++ K+ RW R + L E +IE
Sbjct: 22746 TTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENH 22805
Query: 689 AYEVRIFAVNAIGISKPSMPS---RPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIG 745
YE R+ A NA G+S+PS PS + P+ PP V +T ++V + W P + G
Sbjct: 22806 DYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPIYDG 22865
Query: 746 AAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDL-IDKTKFTITGLPTDA 804
+ GY++E C D+ +W + I+KT + L
Sbjct: 22866 GCEIQGYIVEKC------------------DVSVGEWTMCTPPTGINKTNIEVEKLLEKH 22907
Query: 805 KIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQ 864
+ R+ A+N AG E PI+V+E +E P I + L++ R G ++ L +P +
Sbjct: 22908 EYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIK 22967
Query: 865 GKPRPELTW-KKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETAS 923
G+P PE+ W K DG D I++ +S T + + R SGKY L ++ ++A
Sbjct: 22968 GRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLV--LDNVNRYDSGKYTLTLENSSGTKSAF 23025
Query: 924 IDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIE 983
+ ++++D P PP +K+ ++ ++V++TW PP DG + I Y ++K + + V+
Sbjct: 23026 VTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVT 23085
Query: 984 HYHRTSATITELVIGNEYYFRVFSENMCGL---SEDATMTKESAVIARDGKI 1032
+ H+ S I +L G YYFRV +EN G+ ++ A K + V GKI
Sbjct: 23086 NCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKI 23137
Score = 216 bits (550), Expect = 1e-55
Identities = 154/518 (29%), Positives = 249/518 (48%), Gaps = 36/518 (6%)
Query: 505 PDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDK 564
P N + AK +++ P+I LD + +V AG +++ IP G PPP W R D+
Sbjct: 27253 PIEMNEPVQAK-DILEAPEIDLD-VALRTSVIAKAGEDVQVLIPFKGRPPPTVTW-RKDE 27309
Query: 565 AIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHAS-IKVKVVDFPDPP 623
+ R E+ SS L I R+D+G Y + ++N GE +S + VKV+D P
Sbjct: 27310 KNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAAC 27369
Query: 624 VAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKK 683
V V + W+PP DGGSPI+ Y IE++ W ++ C T+F+
Sbjct: 27370 QKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHK-CSSTSFKLID 27428
Query: 684 MIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDH 743
+ E + R+ A N IGI +P + P V +P L++ T T+V + W PD
Sbjct: 27429 LSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDF 27488
Query: 744 IGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKT-KFTITGLPT 802
G + + YV+E +G + W A I KT + ++ L
Sbjct: 27489 DGGSVITEYVVERKGKGE------------------QTWSHAG---ISKTCEIEVSQLKE 27527
Query: 803 DAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIP 862
+ + RV A N G S+P PI VKE+I P++ + R+G V+L +P
Sbjct: 27528 QSVLEFRVFAKNEKGLSDPVTIG-PITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELP 27586
Query: 863 FQGKPRPELTWKKDGAEIDKNQ-INIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVET 921
++GKP+P ++W KDG + +++ + +E + I+ A++ H GKY V +D V
Sbjct: 27587 YKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYT--VILDNAVCR 27644
Query: 922 ASIDIQIIDRPGPPQI----VKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSME 977
++ I +I GPP ++ +++ ++V L+W P+D+G IT Y+I+K +
Sbjct: 27645 IAVPITVITL-GPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTN 27703
Query: 978 WFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1015
W V RT+ + LV EY FRV +EN G+S+
Sbjct: 27704 WKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQ 27741
Score = 214 bits (546), Expect = 3e-55
Identities = 142/494 (28%), Positives = 224/494 (45%), Gaps = 36/494 (7%)
Query: 573 IRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG-----EAHASIKVKVVDFPDPPVAPT 627
+ S P T I V+ I +N+ G ++ + P P PT
Sbjct: 16265 VHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPT 16324
Query: 628 VTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETT----FEPKK 683
V+ V + +NWE P YDGGSP+ GY++E K S RW R+N D K T ++
Sbjct: 16325 VSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKVTG 16384
Query: 684 MIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRP 740
+IEG Y+ R++A+NA G+ S+PS P P+A PP V T ++ + W P
Sbjct: 16385 LIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPP-FPKVTDWTKSSADLEWSP 16443
Query: 741 PDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGL 800
P G + + GY++EY EG E+W + TK +TGL
Sbjct: 16444 PLKDGGSKVTGYIVEYKEEGK------------------EEWEKGKDKEVRGTKLVVTGL 16485
Query: 801 PTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLV 860
A RV+AVN AG EP + I +K+ + P +++ ++ + G + ++
Sbjct: 16486 KEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRII 16545
Query: 861 IPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVE 920
GKP P +TW + + + + I + + + I+ +RSH G Y L K +
Sbjct: 16546 AYVSGKPPPTVTWNMNERTLPQ-EATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGER 16604
Query: 921 TASIDIQIIDRPGPPQIVKI-EDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF 979
+I + ++D PGP + ++ E+ LTW P+DDG + IT Y I+K + W
Sbjct: 16605 KKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWT 16664
Query: 980 TVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYE 1039
V R +AT+ L+ G Y+FR+ +EN G+ T E+ VI + + P E
Sbjct: 16665 PVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMG-PFVETSEALVIREPITVPERP--E 16721
Query: 1040 DFDFSEAPMFTQPL 1053
D + E T L
Sbjct: 16722 DLEVKEVTKNTVTL 16735
Score = 211 bits (537), Expect = 3e-54
Identities = 160/553 (28%), Positives = 257/553 (46%), Gaps = 70/553 (12%)
Query: 502 VFAPDAYNVTLPAKV--HVI--DP---PKIILDGLDADNTVTVIAGNKLRLEIPISGEPP 554
V A +A V+ P+++ +V+ DP P I L+ D + VI G KL + +P P
Sbjct: 14360 VRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHD----IIVIEGEKLSIPVPFRAVPV 14415
Query: 555 PKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKV 614
P W + K + + S R+ ++ S+ L + + R D+G+Y I L+N+ G A ASI V
Sbjct: 14416 PTVSWHKDGKEV-KASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINV 14474
Query: 615 KVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLC 674
KV+ P P +++ C + WEPP +DGG+PIL Y +ER++ ++ +
Sbjct: 14475 KVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGEN 14534
Query: 675 KETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTD 731
K ++ K +I Y R+ AVN +G + P + P PP + V + T
Sbjct: 14535 K-LSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTA 14593
Query: 732 TTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLID 791
+T+ W+PP + G + + GY++E +G E W N+ L+
Sbjct: 14594 EAMTITWKPPLYDGGSKIMGYIIEKIAKGE------------------ERWKRCNEHLVP 14635
Query: 792 KTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIR 851
+T GL + RV+A NAAG SEP + P + I+ PK+ + L+ ++
Sbjct: 14636 ILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLE---VK 14692
Query: 852 RVGEAVNLVIPFQGKPRPELTWKKD-----GAEIDK------------------------ 882
R G+ + L G P P +TW KD EI K
Sbjct: 14693 R-GDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLT 14751
Query: 883 NQINIRNSET-DTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIE 941
+++I NS+ ++ + +R + R G Y ++V+ D + A + ++D PGPP E
Sbjct: 14752 QRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFE 14811
Query: 942 DVWGENVALTWTPPKDDGNAAITGYTIQKAD--KKSMEWFTVIEHYHRTSATITELVIGN 999
D+ +V W PP DDG + I YT++K D K EW V ++T+L+ G
Sbjct: 14812 DIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGK 14871
Query: 1000 EYYFRVFSENMCG 1012
EY FRV +EN G
Sbjct: 14872 EYLFRVRAENRFG 14884
Score = 210 bits (535), Expect = 5e-54
Identities = 177/671 (26%), Positives = 293/671 (43%), Gaps = 79/671 (11%)
Query: 380 EIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPL 439
+++ G K +RIR + GA A + + + A P +L P
Sbjct: 20337 DLVEGGKYEFRIRAKNTA------GAISAPSESTETIICKDEYEA-------PTIVLDPT 20383
Query: 440 TDQ--TVNLGKEICLKCE--ISENIP-GKWTKNGLPVQESDRLKVVHKGRIHKLVIANAL 494
T+ G I L + + +P W+K G ++ SD ++ L I A
Sbjct: 20384 IKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYAT 20443
Query: 495 TEDEGDY-VFAPDAYNVTLP-AKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGE 552
+D G+Y + A + + + KV V+D P G ++ ++ K L +
Sbjct: 20444 RKDAGEYTITATNPFGTKVEHVKVTVLDVP-----GPPGPVEISNVSAEKATL----TWT 20494
Query: 553 PPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLK----NE---- 604
PP + S I+E ++S L+ + D H+ K NE
Sbjct: 20495 PPLEDGGSPIKSYILEKR---------ETSRLLWTVVSEDIQSCRHVATKLIQGNEYIFR 20545
Query: 605 --------AGEAHASIKVKVVDF---PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILG 653
GE S VK+VD P PP P V+ V + ++W+ P DGGS I G
Sbjct: 20546 VSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITG 20605
Query: 654 YFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV 713
Y +ER++K+S RW+R + + + EG YE R+ A N GI PS S +
Sbjct: 20606 YHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVL 20665
Query: 714 PLAVTSPPTLLTVDSVTDTT---VTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDEN 770
PP + VTDTT ++ W P + G + GYV+E+ G A D
Sbjct: 20666 MKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGD-EAWIKDTT 20724
Query: 771 GEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILV 830
G A + T+F + L T K R+ A+N AG EP +V
Sbjct: 20725 GTA----------------LRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIV 20768
Query: 831 KEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNS 890
+ + P + L++T + R G ++ + +P +G+P PE+TW KD + KN+ NI N+
Sbjct: 20769 EREMAPD-FELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINL-KNRANIENT 20826
Query: 891 ETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVAL 950
E+ T++ I + R +GK+ + ++ ++ ++++++D PGP ++ D+ ++V L
Sbjct: 20827 ESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTL 20886
Query: 951 TWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENM 1010
W P DG + IT Y ++K + + T H+ + +T L G EY+FRV +EN
Sbjct: 20887 HWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENE 20946
Query: 1011 CGLSEDATMTK 1021
G+ E T+
Sbjct: 20947 YGIGEPTETTE 20957
Score = 207 bits (527), Expect = 5e-53
Identities = 119/408 (29%), Positives = 212/408 (51%), Gaps = 24/408 (5%)
Query: 620 PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTF 679
P PP P VT++ + + W P DGGS I GYF+E++ K+S W ++ + ++T
Sbjct: 27066 PGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQ 27125
Query: 680 EPKKMIEGVAYEVRIFAVNAIG---ISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTM 736
+ + E Y+ R+ AVNA G S+PS + P+ PP + + T +++T+
Sbjct: 27126 KVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITL 27185
Query: 737 RWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWI-VANKDLIDKTKF 795
W P + G + + GYV+E +Q +E E+W V+ K + T++
Sbjct: 27186 GWSKPVYDGGSAVTGYVVEI--------RQGEE----------EEWTTVSTKGEVRTTEY 27227
Query: 796 TITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGE 855
++ L + RV AVN AG EP ++P+ K+I+E P+I + L+ + I + GE
Sbjct: 27228 VVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGE 27287
Query: 856 AVNLVIPFQGKPRPELTWKKDGAEIDKN-QINIRNSETDTIIFIRKAERSHSGKYDLQVK 914
V ++IPF+G+P P +TW+KD + + + +I N+++ +++ I + R+ +GKY L ++
Sbjct: 27288 DVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIE 27347
Query: 915 VD-KFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADK 973
+++++ ++++D P Q ++++ V V L W PP DG + I Y I+K D
Sbjct: 27348 NGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDA 27407
Query: 974 KSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTK 1021
W V TS + +L ++FRV +EN G+ E T+
Sbjct: 27408 TKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTE 27455
Score = 206 bits (525), Expect = 8e-53
Identities = 160/599 (26%), Positives = 279/599 (46%), Gaps = 50/599 (8%)
Query: 444 VNLGKEICLKCEI-SENIPGK-WTKNGLPVQESD-RLKVVHKGRIHKLVIANALTEDEGD 500
V+ G+ L+ +I + IP W+K+G ++E+ R+++ + LV+ + + D G
Sbjct: 24719 VHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 24778
Query: 501 YVFAPDAYNVT--LPAKVHVIDPP-----KIILDGLDAD------NTVTVIAGNKLRLEI 547
Y+ T +P V V+D P + + G+ A+ N G + I
Sbjct: 24779 YILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYI 24838
Query: 548 PISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGE 607
I + W++ + + ++ T+ P + + +A Y I E+G
Sbjct: 24839 -IEKRETSRLSWTQVSTEVQALNYKV-TKLLPGNEYIFRVMAVNK----YGIGEPLESGP 24892
Query: 608 AHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWM 667
A K P PP P V+ + D ++ W P DGG+ I GY +E++ K+ RW
Sbjct: 24893 VTACNPYKP---PGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWT 24949
Query: 668 RLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVD 727
+ N + + EG +YE R+ A NA G+ +PS PS + PP +
Sbjct: 24950 KCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNP 25009
Query: 728 SVTDT---TVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIV 784
VTDT +V++ W P + G A + GYV+E EAA A++W
Sbjct: 25010 KVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEV--------------KEAA----ADEWTT 25051
Query: 785 ANKDL-IDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPR 843
+ +FT+T L + + R+ A+N+ G EP ++ +E IEPP+I +
Sbjct: 25052 CTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDA 25111
Query: 844 HLKQTYIRRVGEAVNLVIPFQGKPRPELTWKK-DGAEIDKNQINIRNSETDTIIFIRKAE 902
L++ + R + L + +G+P PE+ W+K +G D+ QI + +S T++ I
Sbjct: 25112 DLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSS--FTMLVIDNVT 25169
Query: 903 RSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAA 962
R SG+Y+L ++ + +TA ++++++D P P + I +V ++V L+W PP DG A
Sbjct: 25170 RFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAK 25229
Query: 963 ITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTK 1021
IT Y ++K + + T+ + +T+ I L G YYFRV + N G+ A T+
Sbjct: 25230 ITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTE 25288
Score = 206 bits (524), Expect = 1e-52
Identities = 159/616 (25%), Positives = 268/616 (43%), Gaps = 73/616 (11%)
Query: 434 KILTPLTDQTVNLGKEICLKCEISENIPG----------KWTKNGLPVQESDRLKVVHKG 483
K++ P + V L + + +K + P KWT +G ++ + V
Sbjct: 17504 KLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDN 17563
Query: 484 RIHKLVIANALTEDEGDYVFAPD--AYNVTLPAKVHVID---PPKIILDGLDADNTVTVI 538
L I N L D G+Y A + T+ + V+D PP ++ LD
Sbjct: 17564 FSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPE---- 17619
Query: 539 AGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIR-----TESYPDSSTLVIDIAERDD 593
+ IS +PP S I+E + S + L I ++
Sbjct: 17620 -------HMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGC 17672
Query: 594 SGVYHINLKNEAG-----EAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGG 648
V+ + +N+ G ++ ++ P PP P VT++ ++ ++W P DGG
Sbjct: 17673 EYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGG 17732
Query: 649 SPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMP 708
SPI GY++ER++ + +W+R+N + F + EG YE R+FA N G+SKPS
Sbjct: 17733 SPITGYYMERREV-TGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPS 17791
Query: 709 SRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAK 765
S P P+ PP + + T + W P G + + GYV+E C + T+
Sbjct: 17792 SDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVE-CQKPGTA-- 17848
Query: 766 QSDENGEAAYDLPAEDWIVANKD-LIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYY 824
W NKD LI + F + GL + R+KA N G EP+
Sbjct: 17849 ---------------QWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPREL 17893
Query: 825 SQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ 884
++ ++ K+I+ PP++ + + RVG+ + ++ +G+P P++TW K+G +
Sbjct: 17894 AESVIAKDILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEG------K 17947
Query: 885 INIRNSETDTI-------IFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQI 937
+ +R D I + I++A R+ GKY + K S + ++DRPGP Q
Sbjct: 17948 VLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQN 18007
Query: 938 VKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVI 997
+K+ +V EN ++W P D+G + IT + ++ W V + L+
Sbjct: 18008 LKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIVASDVTKRLIK-ANLLA 18066
Query: 998 GNEYYFRVFSENMCGL 1013
NEYYFRV +EN G+
Sbjct: 18067 NNEYYFRVCAENKVGV 18082
Score = 204 bits (520), Expect = 3e-52
Identities = 127/423 (30%), Positives = 206/423 (48%), Gaps = 36/423 (8%)
Query: 611 SIKVKVVD---FPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWM 667
S KV + D P PP P V +++W PP +GGSPI GY++E++++ S W
Sbjct: 15587 SDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWS 15646
Query: 668 RLNFDLC-----KETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTS 719
R++ K F +++EGV Y+ R A+NA GI PS PS P V P+
Sbjct: 15647 RVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPG 15706
Query: 720 PPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPA 779
PP+ V T +++++ W+PP G + + GY++E EG+T K+ +E +
Sbjct: 15707 PPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDK------- 15759
Query: 780 EDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKI 839
LI + + L K RVKAVN AG SEP + I +I E P++
Sbjct: 15760 ---------LITTCECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEV 15810
Query: 840 RIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWK---------KDGAEIDKNQINIRNS 890
I + + + G + + +G+P P+ +W+ KDG + +
Sbjct: 15811 FIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETA 15870
Query: 891 ETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVAL 950
E ++I I + +RSH+GKY + K +TA+ ++++D PGPP+ +K+ D+ + L
Sbjct: 15871 ENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRL 15930
Query: 951 TWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENM 1010
+W P DDG I GY I+K W V T+ + +L+ +Y+FRV +EN
Sbjct: 15931 SWKMPDDDGGDRIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENR 15990
Query: 1011 CGL 1013
G+
Sbjct: 15991 FGI 15993
Score = 204 bits (518), Expect = 5e-52
Identities = 146/522 (27%), Positives = 236/522 (45%), Gaps = 39/522 (7%)
Query: 520 DPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYP 579
+PP + LD + + ++AG LR+ ++G P P +W++ + + R+ ++
Sbjct: 15100 EPPAVELD-VSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGEL--DKDRVVIDNVG 15156
Query: 580 DSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMN 639
S L+I A R D G Y I N G A+ +V+V D P P + C++N
Sbjct: 15157 TKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLN 15216
Query: 640 WEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNA 699
W P DGGS I G+ IERK + W R + + + + ++EG Y+ R+ A N
Sbjct: 15217 WSDPEDDGGSEITGFIIERKDAKMHTW-RQPIE-TERSKCDITGLLEGQEYKFRVIAKNK 15274
Query: 700 IGISKPSM--PSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 757
G P P PL + P LT T +T+T+ W+ P G + + GY++E
Sbjct: 15275 FGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIE-- 15332
Query: 758 FEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAG 817
+ +D P D+ NK L T F + L RVKAVN G
Sbjct: 15333 --------------KRRHDKP--DFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIG 15376
Query: 818 ASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIR-RVGEAVNLVIPFQGKPRPELTWKKD 876
SEP +++++ PP I++ ++ I+ + GE V++ G P P++ W K+
Sbjct: 15377 ESEPS-LPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKN 15435
Query: 877 GAEIDK-------NQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQII 929
I+K + + SE T + I KA R G Y + ++ +++
Sbjct: 15436 ETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVY 15495
Query: 930 DRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKAD--KKSMEWFTVIEHYHR 987
DRP PP+ + + D+ E+ LTW P D+G + IT Y I K D +K EW V
Sbjct: 15496 DRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVE 15555
Query: 988 TSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARD 1029
I +L+ +Y FRV + N G+S++ K V+ +D
Sbjct: 15556 KRYGIWKLIPNGQYEFRVRAVNKYGISDEC---KSDKVVIQD 15594
Score = 203 bits (516), Expect = 9e-52
Identities = 164/613 (26%), Positives = 270/613 (44%), Gaps = 62/613 (10%)
Query: 443 TVNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGD 500
T+ G ++ L + K WTK + +++ + + G+ VI D G
Sbjct: 29058 TIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGK 29117
Query: 501 YVFAPDAYNVT--LPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPP---- 554
Y + T + V V+D P G TV+ + K L + E
Sbjct: 29118 YTLTVKNASGTKAVSVMVKVLDSP-----GPCGKLTVSRVTQEKCTLAWSLPQEDGGAEI 29172
Query: 555 -----PKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG--- 606
+ SR + I+EG T SY V+ +++ ++ + N+ G
Sbjct: 29173 THYIVERRETSRLNWVIVEGE--CPTLSY------VVTRLIKNNEYIFRVRAVNKYGPGV 29224
Query: 607 --EAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSS 664
E+ + P PP P G + I+ W P DGG+ I Y +++++K+S
Sbjct: 29225 PVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSL 29284
Query: 665 RWMRLNFD-LCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV----PLAVTS 719
RW R+N D + +T + ++EG Y+ R+ AVNA G S+PS S F+ P
Sbjct: 29285 RWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASN-FISCREPSYTPG 29343
Query: 720 PPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPA 779
PP+ V T ++++ W P + G + GYVLE K +D+
Sbjct: 29344 PPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEM------QEKDTDQ---------- 29387
Query: 780 EDWI-VANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPK 838
W V I T+FT+ L K RV AVN G SE I E IE P
Sbjct: 29388 --WYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPD 29445
Query: 839 IRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFI 898
+ + LK+T R G ++ L++ G+P P +TW K G ++ I I +E+ +++ +
Sbjct: 29446 LELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAI-IDTTESYSLLIV 29504
Query: 899 RKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDD 958
K R +GKY ++ + ++A++ +++ D PGP VK+++V ++V +TW P D
Sbjct: 29505 DKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTID 29564
Query: 959 GNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE--- 1015
G A + Y ++K + + TV +T I+ LV G YYFRV EN+ G+ E
Sbjct: 29565 GGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCE 29624
Query: 1016 --DATMTKESAVI 1026
DA + E ++
Sbjct: 29625 TSDAVLVSEVPLV 29637
Score = 201 bits (512), Expect = 3e-51
Identities = 157/613 (25%), Positives = 280/613 (45%), Gaps = 46/613 (7%)
Query: 420 GQSSAKLSVDLKPLKILTPLTDQ-TVNLGKEICLKCEI-SENIPG-KWTKNGLPVQESDR 476
G +AK V+L + + D VN G+ L+ ++ + +P +W + ++ES R
Sbjct: 23612 GPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESAR 23671
Query: 477 LKVVHKGRIHKLVIANALTEDEGDYVFAPD--AYNVTLPAKVHVIDPPKIILDGLDADNT 534
++ + L++ +A+ D G Y+ A + + P V V+D P +
Sbjct: 23672 CEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRP----GPPEGPVQ 23727
Query: 535 VTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIR-----TESYPDSSTLVIDIA 589
VT + K L + PP + S ++E R S +++L +
Sbjct: 23728 VTGVTSEKCSL----TWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKL 23783
Query: 590 ERDDSGVYHINLKNE--AGEAHASIKVKVVD---FPDPPVAPTVTEVGDDWCIMNWEPPA 644
+ V+ I N+ GE S V + + P PP + VT + D + W P
Sbjct: 23784 LEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPD 23843
Query: 645 YDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISK 704
DGGS I+GY +E++ + RW++ N + + E YE R+ A NA G+ +
Sbjct: 23844 SDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGE 23903
Query: 705 PSMPS---RPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGS 761
PS + + P+ PPT + T ++T+ W P + G + + GYV+E C
Sbjct: 23904 PSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEIC---- 23959
Query: 762 TSAKQSDENGEAAYDLPAEDW-IVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASE 820
++DE E+W IV + + T+F I+ L + +RV A+N G E
Sbjct: 23960 ----KADE----------EEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGE 24005
Query: 821 PKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI 880
+ ++ +E P++ + L++ + R G + + IPF+G+P PE+TW ++ E
Sbjct: 24006 ATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEF 24065
Query: 881 DKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKI 940
+++ I T + I +R+ +GKY L+++ ++A + ++++D PGPPQ + +
Sbjct: 24066 T-DKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAV 24124
Query: 941 EDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNE 1000
++V ++ L W PP DG A + Y I K + + V +TS + L G
Sbjct: 24125 KEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAI 24184
Query: 1001 YYFRVFSENMCGL 1013
YYFRV +EN G+
Sbjct: 24185 YYFRVMAENEFGV 24197
Score = 201 bits (510), Expect = 4e-51
Identities = 139/497 (27%), Positives = 230/497 (46%), Gaps = 32/497 (6%)
Query: 620 PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTF 679
P P P V V + + WE P +DGGS I+GY++E+K++ + W++ N C E +
Sbjct: 28841 PSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNY 28900
Query: 680 EPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWR 739
+ ++EG+ Y+ R +A+NA G+SK S SRP + P V VT +TV++ W
Sbjct: 28901 KVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAPGRPEVTDVTRSTVSLIWS 28960
Query: 740 PPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITG 799
P + G + + GY++E K E G+ W+ N ++ FT+T
Sbjct: 28961 APAYDGGSKVVGYIIE--------RKPVSEVGDGR-------WLKCNYTIVSDNFFTVTA 29005
Query: 800 LPTDAKIFVRVKAVNAAGA-SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIR-RVGEAV 857
L RV A NAAG S+ + P+ ++ PPK + L + R G +
Sbjct: 29006 LSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDL 29065
Query: 858 NLVIPFQGKPRPELTWKKDGAEIDK-NQINIRNSETDTIIFIRKAERSHSGKYDLQVKVD 916
L GKP P++ W K E+D +++++ + I+ +RS SGKY L VK
Sbjct: 29066 VLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNA 29125
Query: 917 KFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSM 976
+ S+ ++++D PGP + + V E L W+ P++DG A IT Y +++ + +
Sbjct: 29126 SGTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRL 29185
Query: 977 EWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNP 1036
W V S +T L+ NEY FRV + N G + ++AR+ +P
Sbjct: 29186 NWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYG---PGVPVESEPIVARNSFTIPSP 29242
Query: 1037 --VYEDFDFSEAPM---FTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMK-NKVAIVDD 1090
+ E+ + + +T+P + G N N V K + W + NK +V D
Sbjct: 29243 PGIPEEVGTGKEHIIIQWTKPESD-----GGNEISNYLVDKREKKSLRWTRVNKDYVVYD 29297
Query: 1091 PRYRMFSNQGVCTLEIR 1107
R ++ S C + R
Sbjct: 29298 TRLKVTSLMEGCDYQFR 29314
Score = 196 bits (497), Expect = 1e-49
Identities = 219/924 (23%), Positives = 366/924 (39%), Gaps = 131/924 (14%)
Query: 263 QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 322
+V + V F E+ + KW++N + I S+KYI K L I + + D + Y
Sbjct: 12650 RVKEQQEVVFNCEVNTEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANY 12709
Query: 323 YVTAGDE-----KCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKN 377
V+ + K + L V E + + + L+D + V C+V+ + +KW KN
Sbjct: 12710 NVSLTNHRGENVKSAANLIVEEEDLRIVEPLKDIETMEKKSVTFWCKVNRLNVTLKWTKN 12769
Query: 378 GEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILT 437
GEE+ + YR V+ KH+L I+ D EY V +S A+L + P + +
Sbjct: 12770 GEEVPFDNRVSYR--VDKYKHMLTIKDCGFPDEGEYIVTAGQDKSVAELLIIEAPTEFVE 12827
Query: 438 PLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTE 496
L DQTV + C++S E KW +NG ++E + K G IH+L+I + +
Sbjct: 12828 HLEDQTVTEFDDAVFSCQLSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLD 12887
Query: 497 DEGDYVFAPD-----AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISG 551
DE +Y + A V +I PP+ IL+ AD V + NK ++E+
Sbjct: 12888 DECEYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGAD-VVFLAELNKDKVEV---- 12942
Query: 552 EPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHAS 611
W R + +++G + DI RD G Y K++ EA A
Sbjct: 12943 ------QWLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQ-GEYRFIAKDK--EARAK 12993
Query: 612 IKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYF-IERKKKQSSRWMRLN 670
+++ AP + D + D G P+ + K + W + N
Sbjct: 12994 LELAA--------APKIKTADQDLVV--------DVGKPLTMVVPYDAYPKAEAEWFKEN 13037
Query: 671 FDL--------CKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPT 722
L ++T+F + +G +I N G ++ + + + V P
Sbjct: 13038 EPLSTKTIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKV---IDVPGPVR 13094
Query: 723 LLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDW 782
L V D V++ W P G + + GYV+E D+ + W
Sbjct: 13095 NLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVE------------------RRDIKRKTW 13136
Query: 783 IVANKDLIDKTKFTITGLPTDAKIFV-RVKAVNAAGASEPKYYSQPILVKEIIEPPKIRI 841
++A D + +FT+TGL ++ RV A N G EP P+ + + P
Sbjct: 13137 VLAT-DRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVP---- 13191
Query: 842 PRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKD----GAEIDKNQINIRNSET---DT 894
G +N+ I + LTW+ GAEI I +R+ + DT
Sbjct: 13192 ------------GPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDT 13239
Query: 895 IIFIRKAERS-------HSGKYDLQVKVDKFV-----ETASIDIQI---IDRPGPPQIVK 939
+ +R + S +Y +V+ + A+ +++ I+RP PP +
Sbjct: 13240 AMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLT 13299
Query: 940 IEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV-IEHYHRTSATITELVIG 998
D +V L W PP DG + I GY I++ ++ W ++ + +T L G
Sbjct: 13300 SSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKG 13359
Query: 999 NEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYA 1058
N+Y +RV +EN G+S+ + + P+ D F E M +
Sbjct: 13360 NKYLYRVSAENKAGVSDPSEIL--------------GPLTADDAFVEPTMDLSAFKDGLE 13405
Query: 1059 IAGYNA-TLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTY 1117
+ N T+ G P+P TW + R +M + L I D G Y
Sbjct: 13406 VIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIY 13465
Query: 1118 CCKAVNDLGTVEIECKLEVKVIAQ 1141
K N + T+ E ++V VIA+
Sbjct: 13466 TLKLENRVKTISGE--IDVNVIAR 13487
Score = 195 bits (496), Expect = 2e-49
Identities = 141/519 (27%), Positives = 228/519 (43%), Gaps = 38/519 (7%)
Query: 518 VIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTES 577
++ PP++ LD + + +TV G +R+ + G P P W++ K ++ R +
Sbjct: 17902 ILHPPEVELD-VTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREK---RVDL 17957
Query: 578 YPDSSTLVIDIAE--RDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDW 635
D + + I E R D G Y I+ KN +G A S V V+D P P VT V +
Sbjct: 17958 IQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKEN 18017
Query: 636 CIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIF 695
C ++WE P +GGS I + +E +K W + D+ K ++ Y R+
Sbjct: 18018 CTISWENPLDNGGSEITNFIVEYRKPNQKGWSIVASDVTKRLI--KANLLANNEYYFRVC 18075
Query: 696 AVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGY 752
A N +G+ P + P+ P L + T V ++WR PD+ G + Y
Sbjct: 18076 AENKVGVGPTIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSY 18135
Query: 753 VLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKA 812
+E +GS +DW +K I +T + + + RV+
Sbjct: 18136 HVERRLKGS------------------DDWERVHKGSIKETHYMVDRCVENQIYEFRVQT 18177
Query: 813 VNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELT 872
N G S+ ++ ++VKE ++ P + + L + G+ + L +GKP PE+
Sbjct: 18178 KNEGGESD-WVKTEEVVVKEDLQKPVLDLK--LSGVLTVKAGDTIRLEAGVRGKPFPEVA 18234
Query: 873 WKKDGAEIDKNQ---INIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQII 929
W KD D + + I + + KA+RS GKY + A + ++
Sbjct: 18235 WTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVL 18294
Query: 930 DRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTS 989
D+PGP + +KI DV + + W PP+DDG I Y ++K + K M W T
Sbjct: 18295 DKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPG 18354
Query: 990 ATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIAR 1028
T+T L+ GNEY FRV +EN G T+ VIA+
Sbjct: 18355 TTVTRLIEGNEYIFRVRAENKIGTGPP---TESKPVIAK 18390
Score = 195 bits (495), Expect = 2e-49
Identities = 123/422 (29%), Positives = 206/422 (48%), Gaps = 28/422 (6%)
Query: 620 PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTF 679
P PP A V +V + WEPP DGG PI Y IE+K++ +RW++ + F
Sbjct: 14184 PGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNF 14243
Query: 680 EPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTM 736
+IEG + ++ A N G+ PS P+ P + SPP L V + +
Sbjct: 14244 RVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAI 14303
Query: 737 RWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFT 796
W+PP+ G + + GY +E C G+ E W+ N I KF
Sbjct: 14304 AWKPPEKNGGSPIIGYHVEMCPVGT------------------EKWMRVNSRPIKDLKFK 14345
Query: 797 IT-GLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGE 855
+ G+ D + +RV+AVNA G SEP S+ ++ K+ P I + H I GE
Sbjct: 14346 VEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETH---DIIVIEGE 14402
Query: 856 AVNLVIPFQGKPRPELTWKKDGAEID-KNQINIRNSETDTIIFIRKAERSHSGKYDLQVK 914
+++ +PF+ P P ++W KDG E+ +++ ++N + + K+ R+ +G Y + ++
Sbjct: 14403 KLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLE 14462
Query: 915 VDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKK 974
TASI++++I PGP + +K D+ + LTW PP+ DG I Y +++ +
Sbjct: 14463 NKLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAG 14522
Query: 975 SMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYK 1034
+ V+ ++ S T+ +L+ EY+FRV + N G E + ++ VIA+D K
Sbjct: 14523 RRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIEL--KNPVIAQDPKQPP 14580
Query: 1035 NP 1036
+P
Sbjct: 14581 DP 14582
Score = 194 bits (493), Expect = 4e-49
Identities = 148/575 (25%), Positives = 258/575 (44%), Gaps = 49/575 (8%)
Query: 464 WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAK----VHVI 519
W K+G+ +++ +++ L + +A + G V+ +A N + AK V V
Sbjct: 27992 WFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRG--VYTVEAKNASGSAKAEIKVKVQ 28049
Query: 520 DPPKIILDGLDADNTVTVIAGNKLRL--EIPISGEPPP-------KAMWSRGDKAIMEGS 570
D P ++ + N I G K+ L + P++ P K SR A++E
Sbjct: 28050 DTPGKVVGPIRFTN----ITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIED- 28104
Query: 571 GRIRTESYPDSSTLVIDIAERDDSGV--YHINLKNEAGEAHASIKVKVVDFPDPPVAPTV 628
+ +SY + + + S V + + ++ A I+ V PD P P
Sbjct: 28105 -KCEAQSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTV---PDAPGIPEP 28160
Query: 629 TEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMR-LNFDLCKETTFEPKKMIEG 687
+ + + + W P DGGS I Y +ER++K+S+RW++ ++ ET F+ + EG
Sbjct: 28161 SNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEG 28220
Query: 688 VAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHI 744
YE + A NA G+ S SR P+ PPT++ V + TTV++ W P
Sbjct: 28221 NEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFD 28280
Query: 745 GAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDA 804
G + GY++E C DW N + KT++T+T L
Sbjct: 28281 GGMEIIGYIIEMC------------------KADLGDWHKVNAEACVKTRYTVTDLQAGE 28322
Query: 805 KIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQ 864
+ RV A+N AG + + I + + P++ I + KQT++ R G ++ L I +Q
Sbjct: 28323 EYKFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQ 28382
Query: 865 GKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASI 924
G+P P W K + + + +I +++ + + + R+ +GKY L V+ + ++ +
Sbjct: 28383 GRPTPTAVWSKPDSNLSL-RADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITF 28441
Query: 925 DIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEH 984
++++D PGPP + +DV + L W P DG A I Y ++K + W + E
Sbjct: 28442 TVKVLDTPGPPGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEK 28501
Query: 985 YHRTSATITELVIGNEYYFRVFSENMCGLSEDATM 1019
R + +L G YYFRV + N G+ E M
Sbjct: 28502 CTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEM 28536
Score = 185 bits (470), Expect = 2e-46
Identities = 172/692 (24%), Positives = 288/692 (41%), Gaps = 92/692 (13%)
Query: 373 KWFKNGEEIIP-----------GPKSRYRIRVEGKKHILIIEGATKA-------DAAEYS 414
+W + E ++P G + ++R+R E I AT DA +
Sbjct: 14625 RWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVI 14684
Query: 415 VMTT-----GGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKC---------EISENI 460
+ T+ G + + S+ P +T + D+ V + +EI + E+ E
Sbjct: 14685 LRTSLEVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEE 14744
Query: 461 PGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYN--VTLPAKVHV 518
P LP+ + + KG +L + ++L D G Y+ + + P V V
Sbjct: 14745 PFV-----LPLTQRLSIDNSKKGE-SQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSV 14798
Query: 519 IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESY 578
+D P ++ + D T + EPP G I+ + + ++
Sbjct: 14799 LDTPGPPINFVFEDIRKTSVL---------CKWEPP----LDDGGSEIINYTLEKKDKTK 14845
Query: 579 PDSSTLVIDIAERD-----------DSGVYHINLKNEAGEAHASIKVKVVDF-----PDP 622
PDS +V+ R ++ + +N G + +V PD
Sbjct: 14846 PDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPFGPPDA 14905
Query: 623 PVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPK 682
P P V +V + ++ W P D GSPILGY++E+++ S+ W R+N L
Sbjct: 14906 PDKPIVEDVTSNSMLVKWNEPK-DNGSPILGYWLEKREVNSTHWSRVNKSLLNALKANVD 14964
Query: 683 KMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSP--PTLLTVDSVTDTTVTMRWRP 740
++EG+ Y R+ A NA G K S PS P SP P + V + TT+ + W P
Sbjct: 14965 GLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIELEWEP 15024
Query: 741 PDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGL 800
P G + GY ++ G+ +W + +I ++T+ +
Sbjct: 15025 PAFNGGGEIVGYFVDKQLVGT------------------NEWSRCTEKMIKVRQYTVKEI 15066
Query: 801 PTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLV 860
A +RV AVNAAG P +QP+ V E EPP + + +K G+ + +
Sbjct: 15067 REGADYKLRVSAVNAAGEGPPG-ETQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIP 15125
Query: 861 IPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVE 920
G+P P W K+ E+DK+++ I N T + + I+ A R G+Y + +
Sbjct: 15126 AVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSK 15185
Query: 921 TASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFT 980
A+ +++ D PGP +K + L W+ P+DDG + ITG+ I++ D K W
Sbjct: 15186 FAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQ 15245
Query: 981 VIEHYHRTSATITELVIGNEYYFRVFSENMCG 1012
IE R+ IT L+ G EY FRV ++N G
Sbjct: 15246 PIE-TERSKCDITGLLEGQEYKFRVIAKNKFG 15276
Score = 184 bits (467), Expect = 4e-46
Identities = 177/720 (24%), Positives = 313/720 (43%), Gaps = 79/720 (10%)
Query: 344 VTKQLEDTTAYCGERVELECE-VSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILII 402
+ K+++D T GE +L C+ V ++KW++ G+E+I K Y++ +G+ H L +
Sbjct: 30535 IRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRK--YKMSSDGRTHTLTV 30592
Query: 403 EGATKADAAEYSVMTTGG----QSSAKLSVDLKP-LKILTPLTDQTVN-LGKEICLKCE- 455
+ D Y+ + T ++S+KL + P PL ++ +G + L
Sbjct: 30593 MTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMY 30652
Query: 456 ISENIPGK-WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPA 514
I +P W +Q S+ + + + LV+ N + Y V L
Sbjct: 30653 IGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAG------KYKVQLSN 30706
Query: 515 KVHVIDPPKIILDGLDADN----TVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIME-- 568
+D ILD D T ++ L+ IS +PP S ++E
Sbjct: 30707 VFGTVDA---ILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKC 30763
Query: 569 -----GSGRIRTESYPDSSTLVIDIAERDDSGVY-HINLKNEAG-----EAHASIKVKV- 616
++ + + ++ ++++ E ++G Y ++ +N G E + + +K
Sbjct: 30764 EAKEGAEWQLVSSAISVTTCRIVNLTE--NAGYYFRVSAQNTFGISDPLEVSSVVIIKSP 30821
Query: 617 VDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKE 676
+ P P PT+T V D C++ W+PPA DGG+ I Y++E+++K+ ++W+ + + +E
Sbjct: 30822 FEKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRE 30881
Query: 677 TTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTM 736
T F K +IEG+ YE R+ N G S+ S S P P + + + + V
Sbjct: 30882 TVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRY 30941
Query: 737 RWRPPDHIGAAGLDGYVLEYCFEG----STSAKQSDENGEAAYDLPAEDWIVANKDLIDK 792
+ G ++++ +G + K + + Y
Sbjct: 30942 QSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYH---------------- 30985
Query: 793 TKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRR 852
+ I + D +V+A N G+ E+ P KI +P+ L+
Sbjct: 30986 -QLIIASVTDDDATVYQVRATNQGGSVSGT------ASLEVEVPAKIHLPKTLEGMGAVH 31038
Query: 853 V--GEAVNLVIPFQGKPRPELTWKKDGAEIDKN---QINIRNSETDTIIFIRKAERSHSG 907
GE V++ IPF GKP P +TW+K ID N Q+ + S T +++F ER +G
Sbjct: 31039 ALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFT-SLVFPNGVERKDAG 31097
Query: 908 KYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYT 967
Y + K ++ ++++ + D P PP+ VK+ DV ++V LTWT P DG + IT Y
Sbjct: 31098 FYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYI 31157
Query: 968 IQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE-----DATMTKE 1022
++K + W V T T+ L Y FRV +EN GLS+ + T+TKE
Sbjct: 31158 VEKCATTAERWLRV-GQARETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKE 31216
Score = 179 bits (455), Expect = 1e-44
Identities = 207/904 (22%), Positives = 363/904 (40%), Gaps = 97/904 (10%)
Query: 270 VRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDE 329
+ F V + + KW KNG EI+ + K K L I N D ++Y AG
Sbjct: 2986 ITFEVTVNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKA 3045
Query: 330 KCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRY 389
+ L+V I K ++D +R ECEVSE D V+W K+ +E+ R
Sbjct: 3046 TSTATLYVEARHIEFRKHIKDIKVLEKKRAMFECEVSEPDITVQWMKDDQEL--QITDRI 3103
Query: 390 RIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKE 449
+I+ E H L+I +DA +Y+V+ G S+AKL V+ + ++I + + V +
Sbjct: 3104 KIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEKQR 3163
Query: 450 ICLKCEISE-NIPGKWTKNGLPV--QESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPD 506
++ E++E ++ W K+G+ + Q +R K V + RIH++ I+ D G+Y F
Sbjct: 3164 AVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAG 3223
Query: 507 AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAI 566
++ V+ +PP++ L VTV +G R ISG P PK W + ++ +
Sbjct: 3224 RNRSSVTLYVNAPEPPQV----LQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLL 3279
Query: 567 MEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG----EAHASIKVKVVDFPD- 621
G + + TL++ A +D+ VY KN+ G A S++V V PD
Sbjct: 3280 STGF-KCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQ 3338
Query: 622 --PPVAPTVTEVGDDWCIMNWEPPAY----DGGSPILGYFIERKKKQSSRWMRLNFDLCK 675
P P + D +P + G + ++ + KK + SR+ R+
Sbjct: 3339 EMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRM------ 3392
Query: 676 ETTFEPKKMIE-GVAY-----EVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSV 729
T FE +E AY A NA+G + L++ +P ++L
Sbjct: 3393 -TQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSST------ANLSLEAPESILHERIE 3445
Query: 730 TDTTVTMRWRPPDHIGAAGLD---GYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVAN 786
+ + M+ P L+ G++ ++ T QS N W A
Sbjct: 3446 QEIEMEMKAAPVIKRKIEPLEVALGHLAKF-----TCEIQSAPNVRF-------QWFKAG 3493
Query: 787 KDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQ--------PILVKEIIEPPK 838
+++ + K +I + + + V G K ++ + V E P
Sbjct: 3494 REIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPPTF 3553
Query: 839 IRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKN-QINIRNSETDTIIF 897
+ P+ L VG+A + G P E W+KDGA + + I ++E I+
Sbjct: 3554 LSRPKSLTTF----VGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWRISDAENKHILE 3609
Query: 898 IRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPG-PPQIVKIEDVWGENVALTWTPPK 956
+ G Y + + ++ IID+P ++ ++ + V L +
Sbjct: 3610 LSNLTIQDRGVYSCKASNKFGADICQAELIIIDKPHFIKELEPVQSAINKKVHLECQVDE 3669
Query: 957 DDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSED 1016
D K ++ W S +L G +Y F + + L
Sbjct: 3670 D--------------RKVTVTW----------SKDGQKLPPGKDYKI-CFEDKIATLEIP 3704
Query: 1017 ATMTKESA--VIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTY-AIAGYNATLNCSVRGN 1073
K+S V + + E P F + + +Y + G +A L+C ++G+
Sbjct: 3705 LAKLKDSGTYVCTASNEAGSSSCSATVTVREPPSFVKKVDPSYLMLPGESARLHCKLKGS 3764
Query: 1074 PKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECK 1133
P ++TW KN + + RM+ L+I D G+Y C+AVND+G+ +
Sbjct: 3765 PVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTE 3824
Query: 1134 LEVK 1137
+ +K
Sbjct: 3825 IVIK 3828
Score = 169 bits (427), Expect = 2e-41
Identities = 165/704 (23%), Positives = 284/704 (40%), Gaps = 93/704 (13%)
Query: 350 DTTAYCGERV-ELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKA 408
D CGE V E + EV+ + KW+ YR++ + +GA+K
Sbjct: 13632 DKWVACGEPVAETKMEVTGLEEG-KWYA------------YRVKALNR------QGASKP 13672
Query: 409 DAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGK--WTK 466
+ Q + ++ +D+K L LT V G +I L ++ K WTK
Sbjct: 13673 SRPTEEIQAVDTQEAPEIFLDVKLLAGLT------VKAGTKIELPATVTGKPEPKITWTK 13726
Query: 467 NGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNV----TLPAKVHVIDP- 521
+ +++ R+ + + + + I ++ D G Y+ +A NV T +V+V+D
Sbjct: 13727 ADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYII--EAVNVCGRATAVVEVNVLDKP 13784
Query: 522 -PKIILDGLDADNTVTVIAGNKLR-------LEIPISGEPPPKAMWSRGDKAIMEGSGRI 573
P D D N ++ N R + +W + + + + +
Sbjct: 13785 GPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFK- 13843
Query: 574 RTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGD 633
T+ P+ + AE +Y + +A A + D P PP +++
Sbjct: 13844 ATKLIPNKEYIFRVAAE----NMYGVGEPVQASPITAKYQ---FDPPGPPTRLEPSDITK 13896
Query: 634 DWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVR 693
D + W P DGGSPI GY++ER + +W+R N K+TT+ K + Y R
Sbjct: 13897 DAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFR 13956
Query: 694 IFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLD 750
+ A N G KPS + P + P+ PP TV V T+V + W P+H G A ++
Sbjct: 13957 VLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIE 14016
Query: 751 GYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRV 810
YV+E G+ ++W+ + + T+ + GL + RV
Sbjct: 14017 SYVIEMLKTGT------------------DEWVRVAEG-VPTTQHLLPGLMEGQEYSFRV 14057
Query: 811 KAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRP- 869
+AVN AG SEP S P+L +E + PP PR L+ I + + +P + P
Sbjct: 14058 RAVNKAGESEPSEPSDPVLCREKLYPPS--PPRWLEVINITKNTADLKWTVPEKDGGSPI 14115
Query: 870 -----------ELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKF 918
W+ + + + ++ R A + G+ D
Sbjct: 14116 TNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTE----- 14170
Query: 919 VETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEW 978
+E + + PGPP + + DV +V L W PPK+DG I Y I+K ++ W
Sbjct: 14171 IEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRW 14230
Query: 979 FTVIEHY-HRTSATITELVIGNEYYFRVFSENMCGLSEDATMTK 1021
+ + +T+++ G E F+V +EN G+ + T+
Sbjct: 14231 VKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTE 14274
Score = 167 bits (423), Expect = 5e-41
Identities = 128/513 (24%), Positives = 216/513 (42%), Gaps = 72/513 (14%)
Query: 28 AGTTPAKDWTLVETPPGEEQAKQNANSQLSILFIEKPQGGTVKVGEDITFIAKVKAEDLL 87
AG+ K ++ P A + A + F+ +PQ V TFIAKV + +
Sbjct: 8424 AGSDTTKSKVTIKDKPAVAPATKKAAVDGRLFFVSEPQSIRVVEKTTATFIAKVGGDPI- 8482
Query: 88 RKPTIKWFKGKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYK 147
P +KW KGKW L + H + +++I +G YRC +
Sbjct: 8483 --PNVKWTKGKWRQLNQGGRVFI--------HQKGDEAKLEIRDTTKTDSGLYRCVAFNE 8532
Query: 148 DKFDSCSFDLEVHESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREV--KQQEEE 205
+ +L+V E +++ E D +LK+ + K EE
Sbjct: 8533 HGEIESNVNLQVDERK------------------KQEKIEGDLRAMLKKTPILKKGAGEE 8574
Query: 206 PQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLK-------------------RLKRMRR 246
++D+ ELLKN P EYEK A YGITD RG+L+ ++R R
Sbjct: 8575 EEIDIMELLKNVDPKEYEKYARMYGITDFRGLLQAFELLKQSQEEETHRLEIEEIERSER 8634
Query: 247 EEKKSAAFAKIL-------DPAYQV----------DKGGRVRFVVELADPKLEVKWYKNG 289
+EK+ + +P + D +++ P++++ WYK
Sbjct: 8635 DEKEFEELVSFIQQRLSQTEPVTLIKDIENQTVLKDNDAVFEIDIKINYPEIKLSWYKGT 8694
Query: 290 QEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLE 349
+++ PS K+ G + L + NCQ+ D Y + G S +L V EP + L+
Sbjct: 8695 EKLEPSDKFEISIDGDRHTLRVKNCQLKDQGNYRLVCGPHIASAKLTVIEP--AWERHLQ 8752
Query: 350 DTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKAD 409
D T G+ + C+ S + +WF+NG I P+ R++ VE K H L I D
Sbjct: 8753 DVTLKEGQTCTMTCQFSVPNVKSEWFRNGR--ILKPQGRHKTEVEHKVHKLTIADVRAED 8810
Query: 410 AAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEIS-ENIPGKWTKNG 468
+Y+ ++SA+L ++ +P++ + + V+ + +CE+S ++ W K
Sbjct: 8811 QGQYTCKYEDLETSAELRIEAEPIQFTKRIQNIVVSEHQSATFECEVSFDDAIVTWYKGP 8870
Query: 469 LPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 501
+ ES + + GR H + I N +DEG Y
Sbjct: 8871 TELTESQKYNFRNDGRCHYMTIHNVTPDDEGVY 8903
Score = 162 bits (411), Expect = 1e-39
Identities = 110/364 (30%), Positives = 175/364 (48%), Gaps = 16/364 (4%)
Query: 264 VDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYY 323
V G F EL+ + V+WY G+++ PS K + +G L + + ++ D E
Sbjct: 12207 VTAGETATFDCELSYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQ 12266
Query: 324 VTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIP 383
+TA D K LFV+EPP+ TK LED T G LECEVS ++A VKWFKNG EI+
Sbjct: 12267 LTAKDFKTHANLFVKEPPVEFTKPLEDQTVEEGATAVLECEVSRENAKVKWFKNGTEILK 12326
Query: 384 GPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQT 443
K Y I +G+ L+I T D Y+ ++S L+V ++ L PLTD
Sbjct: 12327 SKK--YEIVADGRVRKLVIHDCTPEDIKTYTCDAKDFKTSCNLNVVPPHVEFLRPLTDLQ 12384
Query: 444 VNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV 502
V + +CE+S EN KW K+G +++ + ++ KG + LVI L +DE +Y
Sbjct: 12385 VREKEMARFECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEY- 12443
Query: 503 FAPDAYNVTLPAKVHVIDPPKII---LDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMW 559
+ + + V++ + L ++ T T+ KL E+ +P + +W
Sbjct: 12444 -SCEVRTARTSGMLTVLEEEAVFTKNLANIEVSETDTI----KLVCEV---SKPGAEVIW 12495
Query: 560 SRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDF 619
+GD+ I+E +GR + LVI A +D+G Y+ L + + + +F
Sbjct: 12496 YKGDEEIIE-TGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEF 12554
Query: 620 PDPP 623
P
Sbjct: 12555 ISKP 12558
Score = 152 bits (383), Expect = 2e-36
Identities = 107/326 (32%), Positives = 162/326 (49%), Gaps = 37/326 (11%)
Query: 519 IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESY 578
+DPP+I +D D T+ V AG +++ I G+P P W +GD+ + + R+ +S
Sbjct: 22538 VDPPRISMDPKYKD-TIVVHAGESFKVDADIYGKPIPTIQWIKGDQEL-SNTARLEIKST 22595
Query: 579 PDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTV-TEVGDDWCI 637
+++L + A R DSG Y + KN AGE ++ VKV+D P PP P V + V + C
Sbjct: 22596 DFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCT 22655
Query: 638 MNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDL----CKETTFEPKKMIEGVAYEVR 693
+ W+PP DGGS I+ Y +ER++ W ++ ++ CK T K++EG Y R
Sbjct: 22656 LAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVT-----KLLEGNEYTFR 22710
Query: 694 IFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLD 750
I AVN G+ +P + S P V P V P V +VT ++ + W P G + +
Sbjct: 22711 IMAVNKYGVGEP-LESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEIL 22769
Query: 751 GYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRV 810
GYVLE + D+ G W +K LI + + +TGL + RV
Sbjct: 22770 GYVLE----------KRDKEGIR--------WTRCHKRLIGELRLRVTGLIENHDYEFRV 22811
Query: 811 KAVNAAGASEPKYYSQPILVKEIIEP 836
A NAAG SEP S P ++ +P
Sbjct: 22812 SAENAAGLSEP---SPPSAYQKACDP 22834
Score = 150 bits (380), Expect = 5e-36
Identities = 213/914 (23%), Positives = 352/914 (38%), Gaps = 109/914 (11%)
Query: 254 FAKILDPAYQVDKGGRVRFVVELA-DPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFIN 312
F K L+P+ V + R+ ++ P+++V WYK+ EI+ S+K+ +L ++
Sbjct: 7307 FIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEMH 7366
Query: 313 NCQMTDDSEY----YVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEV-SE 367
N + D +Y + AG ST L V+EPPI K+ G V LECE+
Sbjct: 7367 NLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPPIF-RKKPHPIETLKGADVHLECELQGT 7425
Query: 368 DDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTG--GQSSAK 425
+V W+K+ E+ G K Y+I E + I AD EY T G +
Sbjct: 7426 PPFHVSWYKDKRELRSGKK--YKIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTCV 7483
Query: 426 LSVDLK-PLKILTPLTDQTVNLGKEICLKCEI--SENIPGKWTKN-GLPVQESDRLKVVH 481
S+ LK P + + L+D + +GKE+ L+ I +E I W K+ G V+ESD + + +
Sbjct: 7484 GSIALKAPPRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISY 7543
Query: 482 KGRIHKLVIANALTEDEGDYV--FAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIA 539
I L + + G Y DA A + V++P I+ + ++ V
Sbjct: 7544 SENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLEPATIV----EKPESIKVTT 7599
Query: 540 GNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHI 599
G+ LE ++G P W + K + + + + S L I DSGVY
Sbjct: 7600 GDTCTLECTVAGTPELSTKWFKDGKE-LTSDNKYKISFFNKVSGLKIINVAPSDSGVYSF 7658
Query: 600 NLKNEAGEAHASIKVKVVDFPDPP--VAPTVTEVGDDWCIMNWEPPAYDGGSPI-LGYFI 656
++N G+ + ++V D PP G + E Y G PI + +F
Sbjct: 7659 EVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVMECKVY-GSPPISVSWFH 7717
Query: 657 ERKKKQSSRWMR--LNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVP 714
E + S R + L + C T + E + + A N G + S P
Sbjct: 7718 EGNEISSGRKYQTTLTDNTCALTV---NMLEESDSGDYTCIATNMAGSDECS------AP 7768
Query: 715 LAVTSPPTLL----TVDSVTDTTVT----MRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQ 766
L V PP+ + +D +T T VT ++ PP + F+GS+
Sbjct: 7769 LTVREPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVS-----------WFKGSSELVP 7817
Query: 767 SDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQ 826
D + D VA +L D T + V +A A+ + +
Sbjct: 7818 GDRCNVSLED------SVAELELFD----VDTSQSGEYTCIVSNEAGKASCTTHLYIKAP 7867
Query: 827 PILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ-I 885
VK + Y G+ + L F G P +TWKK+G + +Q
Sbjct: 7868 AKFVKRL-------------NDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRC 7914
Query: 886 NIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPG-----PPQIVKI 940
NI +E I+ I + +G+Y+ ++ ++ S I I++ P P V +
Sbjct: 7915 NITTTEKSAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILEPPYFVKQLEPVKVSV 7974
Query: 941 EDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNE 1000
D L TP G + K D K T H+ AT+
Sbjct: 7975 GDSASLQCQLAGTPE--------IGVSWYKGDTKLRPTTTYKMHFRNNVATL-------- 8018
Query: 1001 YYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIA 1060
VF++ S + E++V G++ + + P F++ L +
Sbjct: 8019 ----VFNQVDINDSGEYICKAENSV----GEVSASTFLTVQEQKLPPSFSRQLRDVQETV 8070
Query: 1061 GYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCK 1120
G +C++ G+ ++W K+ + D P + TL I K G Y C
Sbjct: 8071 GLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCT 8130
Query: 1121 AVNDLGTVEIECKL 1134
A N +G+ +L
Sbjct: 8131 ATNPIGSASSSARL 8144
Score = 150 bits (379), Expect = 7e-36
Identities = 100/328 (30%), Positives = 160/328 (48%), Gaps = 26/328 (7%)
Query: 522 PKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS 581
P++ L G+ V AG+ +++EIP+ G P P W +GD+ I++ + R+ E+ S
Sbjct: 21063 PELDLRGI-YQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQ-ILKQTQRVNFETTATS 21120
Query: 582 STLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT-VTEVGDDWCIMNW 640
+ L I+ R DSG Y + +N GE I ++V D P PP P EV D+ +W
Sbjct: 21121 TILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSW 21180
Query: 641 EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAI 700
+PP DGG PI Y +E ++ S+ W+ L + + TT++ ++ G+ Y+ R+ A N
Sbjct: 21181 DPPENDGGVPISNYVVEMRQTDSTTWVELATTVIR-TTYKATRLTTGLEYQFRVKAQNRY 21239
Query: 701 GISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 757
G+ P + S V P V PP V +VT ++T+ W P G + + GY +E
Sbjct: 21240 GVG-PGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVE-- 21296
Query: 758 FEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAG 817
+ + NG W +K L+ F +GL RV A N AG
Sbjct: 21297 --------RKERNGIL--------WQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAG 21340
Query: 818 ASEPKYYSQPILVKEIIEPPKIRIPRHL 845
S+P S+P+L + I+PP +P ++
Sbjct: 21341 KSKPSKPSEPMLALDPIDPPGKPVPLNI 21368
Score = 150 bits (379), Expect = 7e-36
Identities = 103/337 (30%), Positives = 165/337 (48%), Gaps = 25/337 (7%)
Query: 506 DAYNVTLPAKV-HVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDK 564
D + LP + ++PP+I + + +TV V AG+ L+++IPISG+P PK SR D
Sbjct: 26457 DPRELLLPVLIKEQLEPPEIDMKNFPS-HTVYVRAGSNLKVDIPISGKPLPKVTLSR-DG 26514
Query: 565 AIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPV 624
++ + R TE ++ T+ + + D+G Y I N +G A I + V+D P PP
Sbjct: 26515 VPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPT 26574
Query: 625 APTV-TEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKK 683
P V +++ ++ + WEPP YDGGS + Y + +++ ++ W ++ + + T + K
Sbjct: 26575 GPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVAR-TMMKVMK 26633
Query: 684 MIEGVAYEVRIFAVNAIGISK--PSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPP 741
+ G Y+ RI A N GIS S +P PP+ V +VT ++T+ W P
Sbjct: 26634 LTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEP 26693
Query: 742 DHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLP 801
G + + GY LE D N W ANK +I T F +T +
Sbjct: 26694 VSNGGSAVVGYHLE----------MKDRNSIL--------WQKANKLVIRTTHFKVTTIS 26735
Query: 802 TDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPK 838
RV A NAAG +P + S+P+L + EPP+
Sbjct: 26736 AGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACEPPR 26772
Score = 149 bits (377), Expect = 1e-35
Identities = 148/568 (26%), Positives = 234/568 (41%), Gaps = 60/568 (10%)
Query: 360 ELEC-EVSEDDANVKWFK----NGEEII-----------PGPKSRYRIRVEGKKHILIIE 403
ELE +S+D ++W K G+EI+ K + R++ K+ I
Sbjct: 30436 ELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQ--FTIG 30493
Query: 404 GATKADAAEYSVMT---TGGQSSAKLSVDLKPLK-------ILTPLTDQTVNLGKEICLK 453
G +A E+ V TG + ++ +K I + D T LG+ L
Sbjct: 30494 GLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLS 30553
Query: 454 CEI-SENIPG-KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY--VFAPDAYN 509
C+I +P KW + G + +S + K+ GR H L + EDEG Y + +
Sbjct: 30554 CQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGE 30613
Query: 510 VTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEG 569
V +K+ + P+ G G+ LRL + G P P W G K +++
Sbjct: 30614 VETSSKLLLQATPQFH-PGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQK-LLQN 30671
Query: 570 SGRIRTESYPDSSTLVI-DIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTV 628
S I E+ + LV+ ++ + +G Y + L N G A + V++ D PD P P V
Sbjct: 30672 SENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIV 30731
Query: 629 TE-VGDDWCIMNWEPPAYDGGSPILGYFIER-KKKQSSRWMRLNFDLCKETTFEPKKMIE 686
E + + +++W+PPA DGGS I Y +E+ + K+ + W +L TT + E
Sbjct: 30732 IEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEW-QLVSSAISVTTCRIVNLTE 30790
Query: 687 GVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDH 743
Y R+ A N GIS P S + P P T+ +VT + + W+PP
Sbjct: 30791 NAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAWKPPAS 30850
Query: 744 IGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTD 803
G A + Y LE ++ +N WI + I +T F++ L
Sbjct: 30851 DGGAKIRNYYLE--------KREKKQN----------KWISVTTEEIRETVFSVKNLIEG 30892
Query: 804 AKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPF 863
+ RVK N G SE S+PI K + L+ +R A LV
Sbjct: 30893 LEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNA-TLVCKV 30951
Query: 864 QGKPRPELTWKKDGAEIDKNQINIRNSE 891
G P+P + W + G EI + + R E
Sbjct: 30952 TGHPKPIVKWYRQGKEIIADGLKYRIQE 30979
Score = 148 bits (373), Expect = 3e-35
Identities = 104/358 (29%), Positives = 163/358 (45%), Gaps = 33/358 (9%)
Query: 491 ANALTEDEGDYVFAPDAYNVT---LPAKVHVIDPPKIILDGLDA----DNTVTVIAGNKL 543
A LTE + +Y F A N P+++ V+ ++ LD D +
Sbjct: 19942 AKDLTEGK-EYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNF 20000
Query: 544 RLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKN 603
RL+IPI G+P P W +G+ + + R+ ES ++TL++ ++ D+G Y I LKN
Sbjct: 20001 RLKIPIKGKPAPSVSWKKGEDPLATDT-RVSVESSAVNTTLIVYDCQKSDAGKYTITLKN 20059
Query: 604 EAGEAHASIKVKVVDFPDPPVAPT-VTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQ 662
AG +I +KVV P P P EV + + W PP DGGS I Y +E++
Sbjct: 20060 VAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSV 20119
Query: 663 SSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTS 719
+++W+ ++TTF ++ EG+ Y R+ A N G+ + + S P V P V
Sbjct: 20120 NNKWVTCA-SAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGE-GLKSEPIVARHPFDVPD 20177
Query: 720 PPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPA 779
P + V +V++ W P G + + GY LE+ S
Sbjct: 20178 APPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLL---------------- 20221
Query: 780 EDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPP 837
W ANK I F +TGL + RV A+N AG +P S+P++ + I+PP
Sbjct: 20222 --WKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPP 20277
Score = 145 bits (365), Expect = 3e-34
Identities = 110/374 (29%), Positives = 173/374 (46%), Gaps = 19/374 (5%)
Query: 263 QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 322
QV + RF EL+ +VKW+K+G EI+ KY KG RIL IN C + D++EY
Sbjct: 12384 QVREKEMARFECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEY 12443
Query: 323 YVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEII 382
+ S L V E + TK L + + ++L CEVS+ A V W+K EEII
Sbjct: 12444 SCEVRTARTSGMLTVLEEEAVFTKNLANIEVSETDTIKLVCEVSKPGAEVIWYKGDEEII 12503
Query: 383 PGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQ 442
RY I EG+K IL+I+ A DA Y+ ++ K+ V + ++ +
Sbjct: 12504 --ETGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNL 12561
Query: 443 TVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 501
+ G++ C IS E+ P +W ++ ++ D+ V+ G+ LV+ +A +D G Y
Sbjct: 12562 EILEGEKAEFVCSISKESFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTY 12621
Query: 502 VF----APDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKA 557
V A A ++T+ K+ ++ P K D V E+ G KA
Sbjct: 12622 VVMVGAARAAAHLTVIEKLRIVVPLK--------DTRVKEQQEVVFNCEVNTEG---AKA 12670
Query: 558 MWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVV 617
W R ++AI + S I + TL I A DD Y+++L N GE S +V
Sbjct: 12671 KWFRNEEAIFDSSKYIILQK-DLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSAANLIV 12729
Query: 618 DFPDPPVAPTVTEV 631
+ D + + ++
Sbjct: 12730 EEEDLRIVEPLKDI 12743
Score = 144 bits (364), Expect = 4e-34
Identities = 208/930 (22%), Positives = 366/930 (39%), Gaps = 128/930 (13%)
Query: 249 KKSAAFAKILDPAYQVDKGGRVRFVVEL-ADPKLEVKWYKNGQEIRPSTKYIFEHKGCQR 307
++ +F K +DP+Y + G R +L P ++V W+KN +E+ S +
Sbjct: 3734 REPPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEA 3793
Query: 308 ILFINNCQMTDDSEYYVTA----GDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELEC 363
IL I + ++ D Y A G + CSTE+ ++EPP + K LE G L+C
Sbjct: 3794 ILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPPSFI-KTLEPADIVRGTNALLQC 3852
Query: 364 EVSEDDA-NVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIE--GATKADAAEYSVMTTG- 419
EVS + WFK+ ++I +S + R+ +K ++ +E AD EY +
Sbjct: 3853 EVSGTGPFEISWFKDKKQI----RSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVVANE 3908
Query: 420 -GQSSAKLSVDLKPLKILTPLTDQTVNLGKE-ICLKCEI--SENIPGKWTKNGLPVQESD 475
G+ + LK D + LG + + L+ + SE I W K ++E
Sbjct: 3909 VGKCGCMATHLLKEPPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDG 3968
Query: 476 RLKVVHKGRIHKLVIANALTEDEGDYVFAPD--AYNVTLPAKVHVIDPPKIILDGLDADN 533
++K+ + L+I + G Y + A + T ++ V +P KII +
Sbjct: 3969 KIKMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKEPAKII----ERAE 4024
Query: 534 TVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDD 593
+ V AG+ LE ++G P K W + + ++ S + R + + L AE D
Sbjct: 4025 LIQVTAGDPATLEYTVAGTPELKPKWYKDGRPLV-ASKKYRISFKNNVAQLKFYSAELHD 4083
Query: 594 SGVYHINLKNEAGEAHASIKVKVVDFPDPPVAP----TVTEVGDDWCIMNWEPPAYDGGS 649
SG Y + NE G + V+D P V V + C ++ + G
Sbjct: 4084 SGQYTFEISNEVGSSSCETTFTVLDRDIAPFFTKPLRNVDSVVNGTCRLDCK---IAGSL 4140
Query: 650 PI-LGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMP 708
P+ + +F + K+ +S R+ F + + E ++ A A N++G SK S
Sbjct: 4141 PMRVSWFKDGKEIAASDRYRIAF-VEGTASLEIIRVDMNDAGNFTCRATNSVG-SKDSSG 4198
Query: 709 SRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSD 768
+ L V PP+ +T D G+A L+ F+GST
Sbjct: 4199 A-----LIVQEPPSFVTKPGSKDVLP----------GSA----VCLKSTFQGSTPLTIR- 4238
Query: 769 ENGEAAYDLPAEDWIVANKDLIDKTKFTIT--GLPTDAKIFV---------RVKAVNAAG 817
W NK+L+ IT L + ++++ K N AG
Sbjct: 4239 -------------WFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAG 4285
Query: 818 ASEPK---YYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWK 874
E + +P E +EP ++ LK+ G+A L G P ++TW
Sbjct: 4286 GVECSANLFVKEPATFVEKLEPSQL-----LKK------GDATQLACKVTGTPPIKITWF 4334
Query: 875 KDGAEI-DKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRP- 932
+ EI + ++ + E+ ++ + SG+Y + + + + S + + + P
Sbjct: 4335 ANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIVKESPY 4394
Query: 933 -----GPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHR 987
P +++K DV + TPP + IT + + ++ T I+ H
Sbjct: 4395 FTKEFKPIEVLKEYDVM-LLAEVAGTPPFE-----ITWFKDNTILRSGRKYKTFIQD-HL 4447
Query: 988 TSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAP 1047
S I + V + E C ++ + + SA + E P
Sbjct: 4448 VSLQILKFVAADA------GEYQCRVTNEVGSSICSARVT---------------LREPP 4486
Query: 1048 MFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIR 1107
F + + +T ++ G A +++G+ +TW+K+ I +D RM V +L +
Sbjct: 4487 SFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTFENNVASLYLS 4546
Query: 1108 KPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1137
G Y C+A ND G L VK
Sbjct: 4547 GIEVKHDGKYVCQAKNDAGIQRCSALLSVK 4576
Score = 143 bits (360), Expect = 1e-33
Identities = 99/322 (30%), Positives = 145/322 (45%), Gaps = 23/322 (7%)
Query: 519 IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESY 578
ID P LD D + V AG LE I G+P P +WS+ K + E + R+ +S
Sbjct: 24702 IDAPNASLDPKYKD-VIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKST 24760
Query: 579 PDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT-VTEVGDDWCI 637
+TLV+ R D G Y + L N G I VKV+D P PP P VT V + C
Sbjct: 24761 IQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCY 24820
Query: 638 MNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAV 697
+ W PP DGG+ I Y IE+++ W +++ ++ + ++ K++ G Y R+ AV
Sbjct: 24821 LAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEV-QALNYKVTKLLPGNEYIFRVMAV 24879
Query: 698 NAIGISKP--SMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLE 755
N GI +P S P P PP+ V ++T ++ + W P G ++GY+LE
Sbjct: 24880 NKYGIGEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILE 24939
Query: 756 YCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNA 815
+ D+ G W NK + + +TGL RV A NA
Sbjct: 24940 ----------KRDKEGVR--------WTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENA 24981
Query: 816 AGASEPKYYSQPILVKEIIEPP 837
AG EP S + + PP
Sbjct: 24982 AGVGEPSEPSVFYRACDALYPP 25003
Score = 140 bits (352), Expect = 9e-33
Identities = 97/357 (27%), Positives = 171/357 (47%), Gaps = 39/357 (10%)
Query: 496 EDEGDYVF---APDAYNVTLPAK----VHVID---PPKIILDGLDADNTVTVIAGNKLRL 545
E++ Y F A A N++ P++ V ++ PP+I L + + +TV AG + L
Sbjct: 19257 EEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLS-VAMKSLLTVKAGTNVCL 19315
Query: 546 EIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEA 605
+ + G+P P W + D +++ + I+ + TL + R DSG Y I +N +
Sbjct: 19316 DATVFGKPMPTVSWKK-DGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSS 19374
Query: 606 GEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSR 665
G A+IK+KV+D P PP + + ++ D +++WEPP DGGS I Y +++++
Sbjct: 19375 GSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPN 19434
Query: 666 WMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGI-----SKPSMPSRPFVPLAVTSP 720
W +++ + T+ +K+IEG Y+ RI A N G+ ++P++ P+ P P
Sbjct: 19435 WAQVSATV-PITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDP 19493
Query: 721 PTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAE 780
P + ++T +T+ W+PP G + + GY+LE + A
Sbjct: 19494 P---VISNITKDHMTVSWKPPADDGGSPITGYLLE------------------KRETQAV 19532
Query: 781 DWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPP 837
+W N+ I + TGL + RV A+N AG +P S+ ++ PP
Sbjct: 19533 NWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPP 19589
Score = 137 bits (344), Expect = 8e-32
Identities = 104/360 (28%), Positives = 172/360 (47%), Gaps = 10/360 (2%)
Query: 272 FVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKC 331
F VEL+ + VKW+KN Q + + + +G + + + D S+ V A
Sbjct: 11948 FTVELSHDNIRVKWFKNDQRLHTTRSVSMQDEGKTHSITFKDLSIDDTSQIRVEAMGMSS 12007
Query: 332 STELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRI 391
+L V E T +L+D T + V L+CE+S+ DA VKWFK+G+EI P + I
Sbjct: 12008 EAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISKADAPVKWFKDGKEIKPSKNA--VI 12065
Query: 392 RVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEIC 451
+ +GKK +LI++ A K+D +Y+ ++S KL ++ + +K++ PL V +
Sbjct: 12066 KADGKKRMLILKKALKSDIGQYTCDCGTDKTSGKLDIEDREIKLVRPLHSVEVMETETAR 12125
Query: 452 LKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNV 510
+ EISE +I W G + ++ ++ +G+IH LV+ N + G F A NV
Sbjct: 12126 FETEISEDDIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTGGVDF--QAANV 12183
Query: 511 TLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGS 570
A + V P++I L VTV AG + +S E P + +G K +E S
Sbjct: 12184 KSSAHLRV--KPRVI-GLLRPLKDVTVTAGETATFDCELSYEDIPVEWYLKGKK--LEPS 12238
Query: 571 GRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTE 630
++ S TL + + +D+G + K+ A+ +K V+F P TV E
Sbjct: 12239 DKVVPRSEGKVHTLTLRDVKLEDAGEVQLTAKDFKTHANLFVKEPPVEFTKPLEDQTVEE 12298
Score = 137 bits (344), Expect = 8e-32
Identities = 134/554 (24%), Positives = 209/554 (37%), Gaps = 88/554 (15%)
Query: 617 VDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKE 676
+D P PP PTV +VG +NW P +DGG+ I Y IE K + W+R+ +
Sbjct: 13981 IDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTT 14040
Query: 677 TTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTT 733
P M EG Y R+ AVN G S+PS PS P + L SPP L V ++T T
Sbjct: 14041 QHLLPGLM-EGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNT 14099
Query: 734 VTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKT 793
++W P+ G + + Y++E D+ + W + + D T
Sbjct: 14100 ADLKWTVPEKDGGSPITNYIVE------------------KRDVRRKGWQTVDTTVKD-T 14140
Query: 794 KFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRV 853
K T+T L + RV A NA G S+ +L K+ P
Sbjct: 14141 KCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTP---------------- 14184
Query: 854 GEAVNLVIPFQGKPRPELTW---KKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYD 910
G L + K +L W K DG + + + T R + + D
Sbjct: 14185 GPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGT----RWVKAGKTAGPD 14240
Query: 911 LQVKVDKFVETASIDIQI-----------------------IDRPGPPQIVKIEDVWGEN 947
+V +E + Q+ P PP + + D ++
Sbjct: 14241 CNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKH 14300
Query: 948 VALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITE--LVIGNEYYFRV 1005
+A+ W PP+ +G + I GY ++ + +W V + E +V EY RV
Sbjct: 14301 IAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRV 14360
Query: 1006 FSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNAT 1065
+ N G+SE + +++ V+A+D E D I G +
Sbjct: 14361 RAVNAIGVSEPSEISEN--VVAKDPDCKPTIDLETHDI-------------IVIEGEKLS 14405
Query: 1066 LNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDL 1125
+ R P P ++W K+ + R M ++ LE+ K D G Y N L
Sbjct: 14406 IPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKL 14465
Query: 1126 GTVEIECKLEVKVI 1139
G+ + VKVI
Sbjct: 14466 GSA--TASINVKVI 14477
Score = 136 bits (343), Expect = 1e-31
Identities = 105/376 (27%), Positives = 169/376 (44%), Gaps = 13/376 (3%)
Query: 247 EEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQ 306
+ K+ F + L +K F E ++P ++VKWYK+G E+ KY
Sbjct: 2169 QAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKV 2228
Query: 307 RILFINNCQMTDDSEY-YVTAGDE--KCSTELFVREPPIMVTKQLEDTTAYCGERVELEC 363
L I +D +Y V DE K + +L V + K+L+D ELEC
Sbjct: 2229 HFLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGELEC 2288
Query: 364 EVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSS 423
VS ++ KW+ N E+ +Y I + L ++ TK D EYS + G +++
Sbjct: 2289 IVSPENIEGKWYHNDVEL--KSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTT 2346
Query: 424 AKLSVDLKPLKILTPLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKVVHK 482
KL + +P+ IL L+DQ V G + L+ ++S E++ G W K+G VQ SDR+ +V
Sbjct: 2347 CKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVID 2406
Query: 483 GRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNK 542
+ H L+I + ED G+Y F A ++ +V V +D + V VI G K
Sbjct: 2407 KQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYS-----VDVITPLKDVNVIEGTK 2461
Query: 543 LRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLK 602
LE +S W D+ I + R++ LVI+ D G Y + +
Sbjct: 2462 AVLECKVSVPDVTSVKWYLNDEQI-KPDDRVQAIVKGTKQRLVINRTHASDEGPYKLIVG 2520
Query: 603 NEAGEAHASI-KVKVV 617
+ S+ K+K++
Sbjct: 2521 RVETNCNLSVEKIKII 2536
Score = 133 bits (335), Expect = 8e-31
Identities = 197/836 (23%), Positives = 326/836 (38%), Gaps = 110/836 (13%)
Query: 337 VREPPIMVTKQLEDTTAY-CGERVELECEVS-EDDANVKWFKNGEEIIPGPKSRYRIRVE 394
V P I V + +DT GE LE +VS ++W K+G+E+ ++ I++
Sbjct: 21456 VEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKEL--EGTAKLEIKIA 21513
Query: 395 GKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKC 454
L+ + +T+ D+ Y++ T AK ++K L P + + + + KC
Sbjct: 21514 DFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGP-PEGPLAVTEVTSEKC 21572
Query: 455 EISENIP-----GKWTKNGLPVQESDRL---KVVHKGRIHKLVIANALTEDEGDY-VFAP 505
+S P K + +E+ RL V + ++ KL + L +E + V A
Sbjct: 21573 VLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAV 21632
Query: 506 DAYNVTLPAKVHVI---------DPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPK 556
+ Y V P + + DPPK + VT I + + + G P
Sbjct: 21633 NKYGVGEPLESEPVLAVNPYGPPDPPK--------NPEVTTITKDSM---VVCWGHPDSD 21681
Query: 557 A-------MWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG--- 606
+ R DKA + ++ D V + E + + I +N AG
Sbjct: 21682 GGSEIINYIVERRDKAGQRWI-KCNKKTLTDLRYKVSGLTEGHEYE-FRIMAENAAGISA 21739
Query: 607 EAHASIKVKVVDF---PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQS 663
+ S K D P PP P V + + W P YDGGS I GY +E +
Sbjct: 21740 PSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEE 21799
Query: 664 SRWMRLNFDL-CKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSM-PSRPFVPLAVTSPP 721
W + K T++ + E Y++RI+A+N+ G+ +P++ P P + P
Sbjct: 21800 DEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPE 21859
Query: 722 TLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAED 781
L D T+ + G +++ + S ++ ++Y L
Sbjct: 21860 IELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESLDKASIESTSSYTL---- 21915
Query: 782 WIVANKDLIDKTKF--TITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEII----- 834
IV N + D K+ T+ FV V+ ++ G Q + VKE+
Sbjct: 21916 LIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPP------QDLKVKEVTKTSVT 21969
Query: 835 ---EPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSE 891
+PP + +K YI E+ + +WK D + E
Sbjct: 21970 LTWDPPLLDGGSKIKN-YIVEKRESTRKAYSTVATNCHKTSWKVDQLQ-----------E 22017
Query: 892 TDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALT 951
+ F AE + + ETA ++ +RP PP + + DV +V+L+
Sbjct: 22018 GCSYYFRVLAENEYG--------IGLPAETAE-SVKASERPLPPGKITLMDVTRNSVSLS 22068
Query: 952 WTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMC 1011
W P+ DG + I GY ++ K S +W T T ATIT L+ G EY FRV ++N
Sbjct: 22069 WEKPEHDGGSRILGYIVEMQTKGSDKWATCAT-VKVTEATITGLIQGEEYSFRVSAQNEK 22127
Query: 1012 GLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI-AGYNATLNCSV 1070
G+S+ ++ VIA+D I P + L NT+ + AG + ++
Sbjct: 22128 GISDPRQLSVP--VIAKDLVI--------------PPAFKLLFNTFTVLAGEDLKVDVPF 22171
Query: 1071 RGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLG 1126
G P P +TW K+ V + R S + L I+ D G Y K N G
Sbjct: 22172 IGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAG 22227
Score = 133 bits (335), Expect = 8e-31
Identities = 89/320 (27%), Positives = 152/320 (47%), Gaps = 26/320 (8%)
Query: 522 PKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS 581
P L G+ + +T AG+ +++PISG P PK W + + E + R+ + D
Sbjct: 28645 PTADLTGI-TNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKE-TDRVSITTTKDR 28702
Query: 582 STLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT-VTEVGDDWCIMNW 640
+TL + + R DSG Y + L+N AG S+ V V+ P P P V+ V + C+++W
Sbjct: 28703 TTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLSW 28762
Query: 641 EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAI 700
P GG+ I Y +E+++ ++ W +N + K T + + + + Y R+ + N
Sbjct: 28763 GEPKDGGGTEITNYIVEKRESGTTAWQLVNSSV-KRTQIKVTHLTKYMEYSFRVSSENRF 28821
Query: 701 GISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 757
G+SKP + S P + P S PT V V+ +++RW P H G + + GY +E
Sbjct: 28822 GVSKP-LESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVE-- 28878
Query: 758 FEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAG 817
+ + N W+ NK + + +TGL + R A+NAAG
Sbjct: 28879 --------KKERNTIL--------WVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAG 28922
Query: 818 ASEPKYYSQPILVKEIIEPP 837
S+ S+PI+ + ++ P
Sbjct: 28923 VSKASEASRPIMAQNPVDAP 28942
Score = 132 bits (331), Expect = 2e-30
Identities = 210/913 (23%), Positives = 358/913 (39%), Gaps = 101/913 (11%)
Query: 254 FAKILDPAYQVDKGGRVRFVVELA-DPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFIN 312
F K L+ + V G R ++A P++ V W++N E+ S KY ++ +N
Sbjct: 5425 FVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQMN 5484
Query: 313 NCQMTDDSEYYVTA----GDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSED 368
N D ++ A G CST++ V+EPP+ + T E V LECE+S
Sbjct: 5485 NLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPPIVETLKNAE-VSLECELSGT 5543
Query: 369 DA-NVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTG--GQSSAK 425
V W+K+ ++ K Y+I + + I +D EY G +
Sbjct: 5544 PPFEVVWYKDKRQLRSSKK--YKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGSDTCV 5601
Query: 426 LSVDLK-PLKILTPLTDQTVNLGKEICLKCEI--SENIPGKWTKNGLPV-QESDRLKVVH 481
+V LK P + ++ L TV G+ L+ I ++ I +W K V +ES+ +++
Sbjct: 5602 CTVKLKEPPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITF 5661
Query: 482 KGRIHKLVIANALTEDEGDYV--FAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIA 539
+ L A A + G Y+ D A + V++P I+ + +TV
Sbjct: 5662 VENVATLQFAKAEPANAGKYICQIKNDGGMRENMATLMVLEPAVIV----EKAGPMTVTV 5717
Query: 540 GNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHI 599
G LE ++G P W + K ++ S + + Y S+L I ER D+G Y
Sbjct: 5718 GETCTLECKVAGTPELSVEWYKDGK-LLTSSQKHKFSFYNKISSLRILSVERQDAGTYTF 5776
Query: 600 NLKNEAGEAHASIKVKVVDFPDPPVAPTVTE-------VGDDWCIMNWEPPAYDGGSPI- 651
++N G++ + VVD D V P+ T V CI+ + G SPI
Sbjct: 5777 QVQNNVGKSSCT---AVVDVSDRAVPPSFTRRLKNTGGVLGASCILECK---VAGSSPIS 5830
Query: 652 LGYFIERKKKQSSRWMRLNF--DLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPS 709
+ +F E+ K S + F ++C T + + A N G +
Sbjct: 5831 VAWFHEKTKIVSGAKYQTTFSDNVC---TLQLNSLDSSDMGNYTCVAANVAGSDECRAVL 5887
Query: 710 RPFVPLAVTSPPTLLTV---DSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQ 766
P + P L V +VT T+V +R PP + F G+ +
Sbjct: 5888 TVQEPPSFVKEPEPLEVLPGKNVTFTSV-IRGTPPFKVN-----------WFRGARELVK 5935
Query: 767 SDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQ 826
D D AE + N D+ ++T V + NA AS +
Sbjct: 5936 GDRCNIYFEDTVAE-LELFNIDISQSGEYTC------------VVSNNAGQAS----CTT 5978
Query: 827 PILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ-I 885
+ VKE K R+ H + G+++ L + G +TWKKDG I ++
Sbjct: 5979 RLFVKEPAAFLK-RLSDHSVEP-----GKSIILESTYTGTLPISVTWKKDGFNITTSEKC 6032
Query: 886 NIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRP-GPPQIVKIEDVW 944
NI +E I+ I + + +G+Y +++ + + + ++ P ++ +E
Sbjct: 6033 NIVTTEKTCILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEPPYFVTELEPLEAAV 6092
Query: 945 GENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFR 1004
G++V+L + G IT + K D K ++ AT+
Sbjct: 6093 GDSVSLQC---QVAGTPEIT-VSWYKGDTKLRPTPEYRTYFTNNVATL------------ 6136
Query: 1005 VFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNA 1064
VF++ S + T E+++ G V+ + P F + L + G
Sbjct: 6137 VFNKVNINDSGEYTCKAENSI----GTASSKTVFRIQERQLPPSFARQLKDIEQTVGLPV 6192
Query: 1065 TLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVND 1124
TL C + G+ ++ W ++ V + DD + V TL+I + G Y C A N
Sbjct: 6193 TLTCRLNGSAPIQVCWYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNP 6252
Query: 1125 LGTVEIECKLEVK 1137
LGT +L +
Sbjct: 6253 LGTASSSARLTAR 6265
Score = 131 bits (329), Expect = 4e-30
Identities = 159/630 (25%), Positives = 262/630 (41%), Gaps = 95/630 (15%)
Query: 267 GGRVRFVVELAD-PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVT 325
GG +R V + P EVKW K EIR + I + L ++N D +Y +T
Sbjct: 22957 GGSLRLFVPIKGRPTPEVKWGKVDGEIRDAA--IIDVTSSFTSLVLDNVNRYDSGKYTLT 23014
Query: 326 AGDEKCSTELFVR-------EPPI--MVTKQLEDTTAYCGERVELECE-------VSEDD 369
+ + FV PP+ VT+ +D+ + E L+ V + +
Sbjct: 23015 LENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKRE 23074
Query: 370 ANVKWF--------KNG---EEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTT 418
A K + KN +++ G +R+ E + I A A+ +
Sbjct: 23075 ATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGI-----GLPAQTADPIKVAE 23129
Query: 419 GGQSSAKLSVDLKPLKILTPLTDQTVNLG---KEICLKCEISENIPGKWTKNGLPVQESD 475
Q K++VD +T +V+L E +I + I K+ E
Sbjct: 23130 VPQPPGKITVD--------DVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECA 23181
Query: 476 RLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYN-----------VTLPAKVHVIDPPKI 524
R+K + + VI N LT+ E +Y+F A N V + AK VI+P
Sbjct: 23182 RVKSL------QAVITN-LTQGE-EYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEP--- 23230
Query: 525 ILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTL 584
D A ++ +V G L++E+PISG P P W++ D ++ + RI D +TL
Sbjct: 23231 --DVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTK-DGLPLKQTTRINVTDSLDLTTL 23287
Query: 585 VIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT-VTEVGDDWCIMNWEPP 643
I +DD G Y I + N G+ ASI++ +D PDPP P +V + ++W PP
Sbjct: 23288 SIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPP 23347
Query: 644 AYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGIS 703
Y GG I Y ++++ ++ W ++ + + TT + K+ G Y+ RIFA N G S
Sbjct: 23348 LYTGGCQITNYIVQKRDTTTTVWDVVSATVAR-TTLKVTKLKTGTEYQFRIFAENRYGQS 23406
Query: 704 KPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEG 760
++ S P V P PP +++ ++ ++W P + G + + GY LE
Sbjct: 23407 F-ALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLE----- 23460
Query: 761 STSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASE 820
+ + N W NK +I T+F L + RV A N G +
Sbjct: 23461 -----RKERNSIL--------WTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGK 23507
Query: 821 PKYYSQPILVKEIIEPPKIRIPRHLKQTYI 850
S+ + ++ +PP P +K+ I
Sbjct: 23508 ASKNSECYVARDPCDPPGTPEPIMVKRNEI 23537
Score = 131 bits (329), Expect = 4e-30
Identities = 92/316 (29%), Positives = 146/316 (46%), Gaps = 25/316 (7%)
Query: 521 PPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPD 580
PPK LD + VT+ AG+ L L+ + G+P PK +W++GDK ++ ++ +
Sbjct: 29043 PPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKE-LDLCEKVSLQYTGK 29101
Query: 581 SSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNW 640
+T VI +R DSG Y + +KN +G S+ VKV+D P P TV+ V + C + W
Sbjct: 29102 RATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAW 29161
Query: 641 EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAI 700
P DGG+ I Y +ER++ W+ + + C ++ ++I+ Y R+ AVN
Sbjct: 29162 SLPQEDGGAEITHYIVERRETSRLNWVIVEGE-CPTLSYVVTRLIKNNEYIFRVRAVNKY 29220
Query: 701 GISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 757
G P + S P V + SPP + + ++W P+ G + Y+++
Sbjct: 29221 GPGVP-VESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKR 29279
Query: 758 FEGSTSAKQSDENGEAAYDLPAEDWIVANKD-LIDKTKFTITGLPTDAKIFVRVKAVNAA 816
+ S W NKD ++ T+ +T L RV AVNAA
Sbjct: 29280 EKKSLR------------------WTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAA 29321
Query: 817 GASEPKYYSQPILVKE 832
G SEP S I +E
Sbjct: 29322 GNSEPSEASNFISCRE 29337
Score = 130 bits (328), Expect = 5e-30
Identities = 80/234 (34%), Positives = 120/234 (51%), Gaps = 8/234 (3%)
Query: 272 FVVELADPKLE-VKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEK 330
F VEL P ++ V+W KNG + + KY KG L I NC + D+S Y G
Sbjct: 2726 FTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGFRLGRLG 2785
Query: 331 CSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYR 390
S L V + + K+ +D TA V E VS D VKWF EI P K +R
Sbjct: 2786 ASARLHVET--VKIIKKPKDVTALENATVAFEVSVSHDTVPVKWFHKSVEIKPSDK--HR 2841
Query: 391 IRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEI 450
+ E K H L+++ + +DA EY+ + GQ K + ++ L I + + V K
Sbjct: 2842 LVSERKVHKLMLQNISPSDAGEYTAVV--GQLECKAKLFVETLHITKTMKNIEVPETKTA 2899
Query: 451 CLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF 503
+CE+S N+P W KNG+ ++ S++ K+V +G++H+L+I N TED +Y F
Sbjct: 2900 SFECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTF 2953
Score = 130 bits (328), Expect = 5e-30
Identities = 197/914 (21%), Positives = 341/914 (37%), Gaps = 88/914 (9%)
Query: 249 KKSAAFAKILDPAYQVDKGGRVRFVVELAD-PKLEVKWYKNGQEIRPSTKYIFEHKGCQR 307
K+ A F + L+P+ + KG + ++ P +++ W+ N +EI+ S+K+
Sbjct: 4296 KEPATFVEKLEPSQLLKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVESTA 4355
Query: 308 ILFINNCQMTDDSEYYVTA----GDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELEC 363
+L + + + D EY A G + CS+ + V+E P TK+ + V L
Sbjct: 4356 VLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIVKESPYF-TKEFKPIEVLKEYDVMLLA 4414
Query: 364 EVSEDDA-NVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTG--G 420
EV+ + WFK+ + G K Y+ ++ L I ADA EY T G
Sbjct: 4415 EVAGTPPFEITWFKDNTILRSGRK--YKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVG 4472
Query: 421 QSSAKLSVDLKPLKILTPLTDQTVNL-GKEICLKCEISENIP--GKWTKNGLPVQESDRL 477
S V L+ + T +L G + + ++P W K+ + E D +
Sbjct: 4473 SSICSARVTLREPPSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNI 4532
Query: 478 KVVHKGRIHKLVIANALTEDEGDYVFAP--DAYNVTLPAKVHVIDPPKIILDGLDADNTV 535
++ + + L ++ + +G YV DA A + V +P I + + D
Sbjct: 4533 RMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPATITEEAVSID--- 4589
Query: 536 TVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSG 595
V G+ L++ SG A W + + + GS + + S L I E+ DSG
Sbjct: 4590 -VTQGDPATLQVKFSGTKEITAKWFKDGQELTLGS-KYKISVTDTVSILKIISTEKKDSG 4647
Query: 596 VYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYF 655
Y ++N+ G + ++ V+D PP + D + GS +
Sbjct: 4648 EYTFEVQNDVGRSSCKARINVLDLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQ 4707
Query: 656 IERKKKQSSRWMRLNFDLCKETTFEPKKMIEGV-AYEVRIFAVNAIGISKPSMPSRPFVP 714
+ ++ S + F T F +EG + A N G ++ S
Sbjct: 4708 WFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCS------GH 4761
Query: 715 LAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAA 774
L V PP + D R + +G + K +N E
Sbjct: 4762 LTVKEPPYFVEKPQSQDVNPNTRVQLKALVGGT------------APMTIKWFKDNKELH 4809
Query: 775 YDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEII 834
W KD + TD+ ++ + N G + K + VKE
Sbjct: 4810 SGAARSVW----KDDTSTSLELFAAKATDSGTYI-CQLSNDVGTATSK---ATLFVKE-- 4859
Query: 835 EPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQIN-IRNSETD 893
P I+ P + R G++ G P+ ++W DG EI Q + I +
Sbjct: 4860 PPQFIKKP---SPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGL 4916
Query: 894 TIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRP------GPPQIVKIEDVWGEN 947
I A +SG Y + + D + SI++++ + P P ++VK DV E
Sbjct: 4917 ATFQISGARVENSGTYVCEARNDAGTASCSIELKVKEPPTFIRELKPVEVVKYSDVELE- 4975
Query: 948 VALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFS 1007
+T TPP + + + +S + +T+ + + IT+ +
Sbjct: 4976 CEVTGTPPFE------VTWLKNNREIRSSKKYTLTDRVSVFNLHITKCDPSDT------G 5023
Query: 1008 ENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLN 1067
E C +S + S +A E P F + + NT + +AT
Sbjct: 5024 EYQCIVSNEGGSCSCSTRVA---------------LKEPPSFIKKIENTTTVLKSSATFQ 5068
Query: 1068 CSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGT 1127
+V G+P ITW+K+ + +D + V TL+IR G Y C+A N+ G
Sbjct: 5069 STVAGSPPISITWLKDDQILDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNESGV 5128
Query: 1128 VEIECKLEVKVIAQ 1141
L V+ AQ
Sbjct: 5129 ERCYAFLLVQEPAQ 5142
Score = 130 bits (328), Expect = 5e-30
Identities = 91/320 (28%), Positives = 147/320 (45%), Gaps = 24/320 (7%)
Query: 522 PKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS 581
P I+ G + + + + +G LR++ + G P P+ W + D +E + S
Sbjct: 27955 PPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFK-DGVEIEKRMNMEITDVLGS 28013
Query: 582 STLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT-VTEVGDDWCIMNW 640
++L + A RD GVY + KN +G A A IKVKV D P V P T + + + W
Sbjct: 28014 TSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWW 28073
Query: 641 EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAI 700
+ P DG +PI Y IE+++ W + D C+ ++ K+I G Y+ R+ AVN
Sbjct: 28074 DAPLNDGCAPITHYIIEKRETSRLAWALIE-DKCEAQSYTAIKLINGNEYQFRVSAVNKF 28132
Query: 701 GISKP--SMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCF 758
G+ +P S P + V P + ++T ++T+ W P+ G + + Y+LE
Sbjct: 28133 GVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERRE 28192
Query: 759 EGSTSAKQSDENGEAAYDLPAEDWI-VANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAG 817
+ ST W+ V +K I +T+F +TGL + V A NAAG
Sbjct: 28193 KKSTR------------------WVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAG 28234
Query: 818 ASEPKYYSQPILVKEIIEPP 837
S+ I +E + PP
Sbjct: 28235 VGPASGISRLIKCREPVNPP 28254
Score = 128 bits (322), Expect = 3e-29
Identities = 101/352 (28%), Positives = 164/352 (46%), Gaps = 15/352 (4%)
Query: 264 VDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYY 323
V +G FV EL+ K+ V W+KN ++ S + +G L + + D S+
Sbjct: 11585 VKEGETATFVCELSHEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIK 11644
Query: 324 VTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIP 383
+ + +L V E T +L D TA + + L+CEVS+ D VKWFK+GEEI+P
Sbjct: 11645 AQVKELSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSK-DVPVKWFKDGEEIVP 11703
Query: 384 GPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQT 443
PK Y I+ +G + IL I+ A D EY ++ A ++V+ + +K+ PL
Sbjct: 11704 SPK--YSIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPLYGVE 11761
Query: 444 VNLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV 502
V +G+ + E+SE ++ G+W G P+ S +++ G+ H L++ N G+
Sbjct: 11762 VFVGETAHFEIELSEPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTGEVS 11821
Query: 503 FAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRG 562
F A N A + V + P I + L + V V ++ + E +S E P W +G
Sbjct: 11822 F--QAANAKSAANLKVKELPLIFITPL---SDVKVFEKDEAKFECEVSRE-PKTFRWLKG 11875
Query: 563 DKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKV 614
+ I G R ++VI A +D Y EA + H S K+
Sbjct: 11876 TQEI-TGDDRFELIKDGTKHSMVIKSAAFEDEAKYMF----EAEDKHTSGKL 11922
Score = 127 bits (319), Expect = 6e-29
Identities = 199/857 (23%), Positives = 322/857 (37%), Gaps = 121/857 (14%)
Query: 319 DSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAY-CGERVELECEV-SEDDANVKWFK 376
DS +TA DE V P I + + DT GE LE +V + ++W +
Sbjct: 23609 DSTGPITAKDE-------VELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLR 23661
Query: 377 NGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKIL 436
+EI +R I+ K +LI++ A + D +Y + + S V++K L
Sbjct: 23662 GDKEI--EESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRP 23719
Query: 437 TPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVVHKGRIHKL-------- 488
P + V + KC ++ + P + G + VV K +L
Sbjct: 23720 GP-PEGPVQVTGVTSEKCSLTWSPPLQ--DGGSDISHY----VVEKRETSRLAWTVVASE 23772
Query: 489 VIANALTEDE----GDYVF---APDAYNVTLPAK-VHVIDPPKIILDGLDADNTVTVIAG 540
V+ N+L + +YVF A + Y V P + V+ +L G VT IA
Sbjct: 23773 VVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAK 23832
Query: 541 NKLRLEIPISGEPPPKAMWSRGDKA--------IMEGSGRIRTESYPDSSTLVIDIAER- 591
+ + + W+R D I+E R + + D+ R
Sbjct: 23833 DSMTV------------CWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRV 23880
Query: 592 -----DDSGVYHINLKNEAGEAH---ASIKVKVVD---FPDPPVAPTVTEVGDDWCIMNW 640
D + ++ +N AG A++ K D P PP + + + + W
Sbjct: 23881 TGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAW 23940
Query: 641 EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDL-CKETTFEPKKMIEGVAYEVRIFAVNA 699
P YDGGS ILGY +E K W + + T FE K+ E Y++R+ A+N
Sbjct: 23941 GKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNK 24000
Query: 700 IGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFE 759
+G+ + + P P L +DS + +R A G + +
Sbjct: 24001 VGLGEATSVPGTVKPEDKLEAPEL-DLDSELRKGIVVR--------AGGSARIHIPFKGR 24051
Query: 760 GSTSAKQSDENGEAAYDLPAEDWI------VANKDLIDKTKFTIT--GLPTDAKIFVRVK 811
+ S E GE + E + + N D D K+ + FV VK
Sbjct: 24052 PTPEITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVK 24111
Query: 812 AVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPEL 871
++ G Q + VKE+ + + + I + N VI + R
Sbjct: 24112 VLDTPGPP------QNLAVKEVRKDSAFLV---WEPPIIDGGAKVKNYVIDKRESTRK-- 24160
Query: 872 TWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDR 931
+ ++ K + N I + R + G V VET ++ +
Sbjct: 24161 AYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFG-------VGVPVETVDA-VKAAEP 24212
Query: 932 PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSAT 991
P PP V + DV + +L W P+ DG + + GY ++ K + +W V E +A
Sbjct: 24213 PSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAES-KVCNAV 24271
Query: 992 ITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQ 1051
+T L G EY FRV + N G S+ + VIA+D I P
Sbjct: 24272 VTGLSSGQEYQFRVKAYNEKGKSDPRVLGVP--VIAKDLTIQ-------------PSLKL 24316
Query: 1052 PLVNTYAI-AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPS 1110
P NTY+I AG + + V G P+P I+W+K+ + R + L I++ +
Sbjct: 24317 PF-NTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGN 24375
Query: 1111 PYDGGTYCCKAVNDLGT 1127
D G Y A N GT
Sbjct: 24376 KDDFGKYTVTATNSAGT 24392
Score = 126 bits (316), Expect = 1e-28
Identities = 125/552 (22%), Positives = 221/552 (40%), Gaps = 66/552 (11%)
Query: 597 YHINLKNEAG---EAHASIKVKVVD---FPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSP 650
Y + +N AG + S ++ D P PP P + + G + W P +DGG+P
Sbjct: 26055 YRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAP 26114
Query: 651 ILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSR 710
I GY +E KK + W + + + T + + G Y R+ +VN +G S PS S
Sbjct: 26115 ITGYTVEYKKSDDTDW-KTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSD 26173
Query: 711 PFVPLAVTSPP----------TLLTVDSVTDT-TVTMRWRPPDHIGAAGLDGYVLEYCFE 759
P + P TL+ + T TV R RP ++ + D + +
Sbjct: 26174 PQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYV 26233
Query: 760 GSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGAS 819
+T ++ S L E+ AN++ K TI + + A + + VK ++ G
Sbjct: 26234 DTTDSRTS---------LTIEN---ANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGPP 26281
Query: 820 EPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAE 879
I V+++ + + L G A + + + W
Sbjct: 26282 TN------ITVQDVTKESAV-----LSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNN 26330
Query: 880 IDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVK 939
++ + N + I + R SG+ + V + ET ++I ++P PP+ +
Sbjct: 26331 CNRLSYKVTNLQEGAIYYFRV-----SGENEFGVGIP--AETKE-GVKITEKPSPPEKLG 26382
Query: 940 IEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF--TVIEHYHRTSATITELVI 997
+ + ++V+LTW P+ DG + I Y ++ +K W V + H + + E
Sbjct: 26383 VTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKCAVAKSTHHVVSGLRE--- 26439
Query: 998 GNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTY 1057
+EY+FRVF+EN GLS+ + + + E + E M P Y
Sbjct: 26440 NSEYFFRVFAENQAGLSDPREL------------LLPVLIKEQLEPPEIDMKNFPSHTVY 26487
Query: 1058 AIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTY 1117
AG N ++ + G P PK+T ++ V + R+ T+ +++ D G Y
Sbjct: 26488 VRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRY 26547
Query: 1118 CCKAVNDLGTVE 1129
A N GT +
Sbjct: 26548 EITAANSSGTTK 26559
Score = 125 bits (315), Expect = 2e-28
Identities = 87/266 (32%), Positives = 123/266 (46%), Gaps = 11/266 (4%)
Query: 247 EEKKSAAFAKIL--DPAYQV---DKGGRVRFVVEL---ADPKLEVKWYKNGQEIRPSTKY 298
+E S A K+L DP + V DK + + L + VKW+K+G+EI PS KY
Sbjct: 11648 KELSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSKDVPVKWFKDGEEIVPSPKY 11707
Query: 299 IFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGER 358
+ G +RIL I + D EY G +K + V I V K L + GE
Sbjct: 11708 SIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPLYGVEVFVGET 11767
Query: 359 VELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTT 418
E E+SE D + +W G+ + P I +GKKHILI+ E S
Sbjct: 11768 AHFEIELSEPDVHGQWKLKGQPLTASPDC--EIIEDGKKHILILHNCQLGMTGEVSFQAA 11825
Query: 419 GGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRL 477
+S+A L V PL +TPL+D V E +CE+S E +W K + DR
Sbjct: 11826 NAKSAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPKTFRWLKGTQEITGDDRF 11885
Query: 478 KVVHKGRIHKLVIANALTEDEGDYVF 503
+++ G H +VI +A EDE Y+F
Sbjct: 11886 ELIKDGTKHSMVIKSAAFEDEAKYMF 11911
Score = 124 bits (312), Expect = 4e-28
Identities = 135/548 (24%), Positives = 203/548 (37%), Gaps = 95/548 (17%)
Query: 620 PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDL-CKETT 678
P PP P V + ++W PAYDGGSPI+GY +E K+ S W+R N ++T
Sbjct: 19589 PGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTR 19648
Query: 679 FEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPP----------TLLTVDS 728
FE ++E Y+ R++AVN IG S PS P + PP TL+
Sbjct: 19649 FEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAG 19708
Query: 729 VTDTT-VTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANK 787
VT V ++ RPP P W N
Sbjct: 19709 VTMRLYVPVKGRPP------------------------------------PKITWSKPNV 19732
Query: 788 DLIDKTKFTITGLPTDAKIFVRVKAVNAAGASE----------PKYYSQPILVKEIIEPP 837
+L D+ I TD F+R + VN A + K Y+ + V + PP
Sbjct: 19733 NLRDRIGLDIKS--TDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPP 19790
Query: 838 -KIRIPRHLKQT--------YIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIR 888
+ + K + I +N V+ Q + +W E K +
Sbjct: 19791 VNVTVKEISKDSAYVTWEPPIIDGGSPIINYVV--QKRDAERKSWSTVTTECSKTSFRVA 19848
Query: 889 NSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENV 948
N E F R + G D D ++ PGP +K+ V +
Sbjct: 19849 NLEEGKSYFFRVFAENEYGIGDPGETRDA--------VKASQTPGPVVDLKVRSVSKSSC 19900
Query: 949 ALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSE 1008
++ W P DG + I GY + +++ +W V++ + +L G EY FRV +E
Sbjct: 19901 SIGWKKPHSDGGSRIIGYVVDFLTEEN-KWQRVMKSLS-LQYSAKDLTEGKEYTFRVSAE 19958
Query: 1009 NMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNC 1068
N G + +T V+ARD + V D D P A N L
Sbjct: 19959 NENGEGTPSEIT----VVARD-----DVVAPDLDLKGLPDLCY-----LAKENSNFRLKI 20004
Query: 1069 SVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTV 1128
++G P P ++W K + + D R + S+ TL + D G Y N GT
Sbjct: 20005 PIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTK 20064
Query: 1129 EIECKLEV 1136
E ++V
Sbjct: 20065 EGTISIKV 20072
Score = 124 bits (310), Expect = 7e-28
Identities = 201/896 (22%), Positives = 341/896 (38%), Gaps = 98/896 (10%)
Query: 279 PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTA----GDEKCSTE 334
P + V W+ G EI KY L +N + +D +Y A G ++CS
Sbjct: 7709 PPISVSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSAP 7768
Query: 335 LFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDA-NVKWFKNGEEIIPGPKSRYRIRV 393
L VREPP V K + G V V +V WFK E++PG R + +
Sbjct: 7769 LTVREPPSFVQKP-DPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPG--DRCNVSL 7825
Query: 394 EGKKHILIIEGATKADAAEYS--VMTTGGQSSAKLSVDLK-PLKILTPLTDQTVNLGKEI 450
E L + + + EY+ V G++S + +K P K + L D ++ GK +
Sbjct: 7826 EDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAKFVKRLNDYSIEKGKPL 7885
Query: 451 CLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY-VFAPDA 507
L+ + P W KNG+ V S R + + L I ++ ED G Y + +A
Sbjct: 7886 ILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCYIENA 7945
Query: 508 YNV-TLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAI 566
+ A++ +++PP + V V G+ L+ ++G P W +GD +
Sbjct: 7946 SGKDSCSAQILILEPPYFVKQL----EPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKL 8001
Query: 567 MEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPP-VA 625
+ + + +TLV + + +DSG Y +N GE AS + V + PP +
Sbjct: 8002 RPTT-TYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLPPSFS 8060
Query: 626 PTVTEVGDDWCIMNWEPPAYDGGSPI-LGYFIERKKKQSSRWMRLNFDLCKETTFEPKKM 684
+ +V + + A G PI + ++ + K + S ++ +F L T K
Sbjct: 8061 RQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSF-LDNTATLNIFKT 8119
Query: 685 IEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHI 744
+A + A N IG + +S L+ + +R P D +
Sbjct: 8120 DRSLAGQYSCTATNPIG--------------SASSSARLILTEGKNPPFFDIRLAPVDAV 8165
Query: 745 GAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDA 804
D E G+ K S W ++++ K+ I+ L A
Sbjct: 8166 VGESAD---FECHVTGTQPIKVS--------------WAKDSREIRSGGKYQISYLENSA 8208
Query: 805 KIFV-----------RVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRV 853
+ V AVN G + + +KE + PP + L +T
Sbjct: 8209 HLTVLKVDKGDSGQYTCYAVNEVGKDS---CTAQLNIKERLIPPSFT--KRLSETVEETE 8263
Query: 854 GEAVNLVIPFQGKPRPELTWKKDGAEIDKN---QINIRNSETDTIIFIRKAERSHSGKYD 910
G + L G + W K+ EI +I +N+ ++ +RKA + +G Y
Sbjct: 8264 GNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITFKNNTL--VLQVRKAGMNDAGLYT 8321
Query: 911 LQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPK-DDGNAAITGYTIQ 969
+V D + I I + PP V+ +++ TP +G +Q
Sbjct: 8322 CKVSNDAGSALCTSSIVIKEPKKPP-------VFDQHL----TPVTVSEGEYVQLSCHVQ 8370
Query: 970 KADKKSMEWFTV---IEHYHRTS---ATITELVIGNEYYFRVFSENMCGLSEDA-TMTKE 1022
++ ++W I+ R S A+ T ++ + + +C S A + T +
Sbjct: 8371 GSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTK 8430
Query: 1023 SAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMK 1082
S V +D K P + F + + AT V G+P P + W K
Sbjct: 8431 SKVTIKD-KPAVAPATKKAAVDGRLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTK 8489
Query: 1083 NKVAIVDDPRYRMFSNQ--GVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
K ++ R+F +Q LEIR + D G Y C A N+ G +E L+V
Sbjct: 8490 GKWRQLNQGG-RVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQV 8544
Score = 121 bits (304), Expect = 3e-27
Identities = 203/910 (22%), Positives = 347/910 (38%), Gaps = 118/910 (12%)
Query: 254 FAKILDPAYQ-VDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFIN 312
F K L+P ++K + V+ D K+ V W K+GQ++ P Y + L I
Sbjct: 3646 FIKELEPVQSAINKKVHLECQVD-EDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEIP 3704
Query: 313 NCQMTDDSEYYVTAGDE----KCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSED 368
++ D Y TA +E CS + VREPP V K GE L C++
Sbjct: 3705 LAKLKDSGTYVCTASNEAGSSSCSATVTVREPPSFVKKVDPSYLMLPGESARLHCKLKGS 3764
Query: 369 DA-NVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYS---VMTTGGQSSA 424
V WFKN +E+ + R+ + IL I D+ YS V G S +
Sbjct: 3765 PVIQVTWFKNNKEL--SESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCS 3822
Query: 425 KLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHK 482
V +P + L + G L+CE+S P + W K+ ++ S + ++ +
Sbjct: 3823 TEIVIKEPPSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQ 3882
Query: 483 GRIHKLVIANALTEDEGDY--VFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAG 540
+ L I + + D G+Y V A + A H++ P + +D + + G
Sbjct: 3883 KSLVCLEIFSFNSADVGEYECVVANEVGKCGCMA-THLLKEPPTFVKKVD---DLIALGG 3938
Query: 541 NKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHIN 600
+ L+ + G P W +G + I E G+I+ + L+I + G Y
Sbjct: 3939 QTVTLQAAVRGSEPISVTWMKGQEVIRE-DGKIKMSFSNGVAVLIIPDVQISFGGKYTCL 3997
Query: 601 LKNEAGEAHASIKVKVVDFPDPPV--APTVTEVGDDWCIMNW--------EPPAYDGGSP 650
+NEAG + S+ +V P + A + D + + +P Y G P
Sbjct: 3998 AENEAG-SQTSVGELIVKEPAKIIERAELIQVTAGDPATLEYTVAGTPELKPKWYKDGRP 4056
Query: 651 ILGYFIERKKKQSSRWMRLNF-DLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKP---- 705
++ +S+ R++F + + F ++ + Y I N +G S
Sbjct: 4057 LV----------ASKKYRISFKNNVAQLKFYSAELHDSGQYTFEIS--NEVGSSSCETTF 4104
Query: 706 SMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAK 765
++ R P T P L VDSV + T + + AG + + +G A
Sbjct: 4105 TVLDRDIAPF-FTKP--LRNVDSVVNGTCRLDCK------IAGSLPMRVSWFKDGKEIA- 4154
Query: 766 QSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYS 825
+ + A+ + D+ D FT +A N+ G+ + S
Sbjct: 4155 -ASDRYRIAFVEGTASLEIIRVDMNDAGNFTC-------------RATNSVGSKDS---S 4197
Query: 826 QPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAE-IDKNQ 884
++V+E PP K G AV L FQG + W K E +
Sbjct: 4198 GALIVQE---PPSFVTKPGSKDVL---PGSAVCLKSTFQGSTPLTIRWFKGNKELVSGGS 4251
Query: 885 INIRNSETDTIIFIRKAERSHSGKYDLQVK-VDKFVE-TASIDIQ----IIDRPGPPQIV 938
I ++ + + + S SG Y +V V VE +A++ ++ +++ P Q++
Sbjct: 4252 CYITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKEPATFVEKLEPSQLL 4311
Query: 939 KIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIG 998
K D +T TPP IT + + K+S + HR S + V+
Sbjct: 4312 KKGDATQLACKVTGTPP-----IKITWFANDREIKESSK--------HRMSFVESTAVLR 4358
Query: 999 -NEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTY 1057
+ E MC +A S+++ E+P FT+
Sbjct: 4359 LTDVGIEDSGEYMCEAQNEAGSDHCSSIVI---------------VKESPYFTKEFKPIE 4403
Query: 1058 AIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTY 1117
+ Y+ L V G P +ITW K+ + +Y+ F + +L+I K D G Y
Sbjct: 4404 VLKEYDVMLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEY 4463
Query: 1118 CCKAVNDLGT 1127
C+ N++G+
Sbjct: 4464 QCRVTNEVGS 4473
Score = 120 bits (301), Expect = 7e-27
Identities = 130/513 (25%), Positives = 208/513 (40%), Gaps = 41/513 (7%)
Query: 96 KGKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSF 155
KG+W+ + GKHL L S + + I K + G Y TYK S
Sbjct: 2649 KGEWL----RDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEY----TYKVATSKTSA 2700
Query: 156 DLEVH--ESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWEL 213
L+V + T N+ + + + +K V + E+ + V
Sbjct: 2701 KLKVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISV--- 2757
Query: 214 LKNAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVD--KGGRVR 271
K + Y I D RL R+ + KI+ V + V
Sbjct: 2758 ----KGTIYSLRIKNCAIVDESVYGFRLGRLGASARLHVETVKIIKKPKDVTALENATVA 2813
Query: 272 FVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKC 331
F V ++ + VKW+ EI+PS K+ + L + N +D EY G +C
Sbjct: 2814 FEVSVSHDTVPVKWFHKSVEIKPSDKHRLVSERKVHKLMLQNISPSDAGEYTAVVGQLEC 2873
Query: 332 STELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRI 391
+LFV + +TK +++ + ECEVS + W KNG EI K ++I
Sbjct: 2874 KAKLFVE--TLHITKTMKNIEVPETKTASFECEVSHFNVPSMWLKNGVEIEMSEK--FKI 2929
Query: 392 RVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEIC 451
V+GK H LII + D+AEY+ + Q SA L+V P+ I + L D +N ++
Sbjct: 2930 VVQGKLHQLIIMNTSTEDSAEYTFVCGNDQVSATLTV--TPIMITSMLKD--INAEEKDT 2985
Query: 452 LKCEISENIPG---KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPD-- 506
+ E++ N G KW KNG+ ++ +D+ ++ K H L I N D DY F
Sbjct: 2986 ITFEVTVNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKA 3045
Query: 507 AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAI 566
TL + I+ K I D + V+ + E +S EP W + D+
Sbjct: 3046 TSTATLYVEARHIEFRKHIKD-------IKVLEKKRAMFECEVS-EPDITVQWMKDDQE- 3096
Query: 567 MEGSGRIRTESYPDSSTLVIDIAERDDSGVYHI 599
++ + RI+ + L+I D+G Y +
Sbjct: 3097 LQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTV 3129
Score = 120 bits (301), Expect = 7e-27
Identities = 89/317 (28%), Positives = 143/317 (45%), Gaps = 11/317 (3%)
Query: 256 KILDPAYQVD--KGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINN 313
K++ P + V+ + RF E+++ + W G+ + + + +G L ++N
Sbjct: 12108 KLVRPLHSVEVMETETARFETEISEDDIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHN 12167
Query: 314 CQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVK 373
C++ A + K S L V+ I + + L+D T GE +CE+S +D V+
Sbjct: 12168 CRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCELSYEDIPVE 12227
Query: 374 WFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPL 433
W+ G+++ P K R EGK H L + DA E + ++ A L V P+
Sbjct: 12228 WYLKGKKLEPSDK--VVPRSEGKVHTLTLRDVKLEDAGEVQLTAKDFKTHANLFVKEPPV 12285
Query: 434 KILTPLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIAN 492
+ PL DQTV G L+CE+S EN KW KNG + +S + ++V GR+ KLVI +
Sbjct: 12286 EFTKPLEDQTVEEGATAVLECEVSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHD 12345
Query: 493 ALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGE 552
ED Y DA + ++V+ P L L + V R E +S E
Sbjct: 12346 CTPEDIKTYTC--DAKDFKTSCNLNVVPPHVEFLRPL---TDLQVREKEMARFECELSRE 12400
Query: 553 PPPKAMWSRGDKAIMEG 569
K W + I +G
Sbjct: 12401 -NAKVKWFKDGAEIKKG 12416
Score = 120 bits (301), Expect = 7e-27
Identities = 124/479 (25%), Positives = 201/479 (41%), Gaps = 76/479 (15%)
Query: 463 KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY--VFAPDAYNVTLPAKVHVID 520
KWTK G + S R + +LVI A D G Y V + KV VI
Sbjct: 30169 KWTKEGQDI--SKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIG 30226
Query: 521 PPKIILDGLDADNTVTVIAGNKLRLEIPISGEPP------------------PKAMWSRG 562
P L+ D+ + +S PP PKA W
Sbjct: 30227 SPNSPEGPLEYDDIQV--------RSVRVSWRPPADDGGADILGYILERREVPKAAWYTI 30278
Query: 563 DKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG-----EAHASIKVKV- 616
D R+R ++LV+ + + + ++ +N+ G ++ + K
Sbjct: 30279 DS-------RVR------GTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTP 30325
Query: 617 VDFPDPPV-APTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCK 675
++ P+PP P V +V ++W P DGGS + GY+IERK+ + +W+R N
Sbjct: 30326 LNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQIT 30385
Query: 676 ETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDT 732
T + ++ Y+ RI A N +G+S+ S S P V P S P L + S++
Sbjct: 30386 TTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKD 30445
Query: 733 TVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDK 792
+VT++W P+ G + GY +EY ++G++A W +NK+ I
Sbjct: 30446 SVTLQWEKPECDGGKEILGYWVEY-----------RQSGDSA-------WKKSNKERIKD 30487
Query: 793 TKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEII-EPPKIRIPRHLKQTYIR 851
+FTI GL + RV A N G S P+ + I K E P IR + +K
Sbjct: 30488 KQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIR--KEMKDV-TT 30544
Query: 852 RVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDT-IIFIRKAERSHSGKY 909
++GEA L G+P P++ W + G E+ +++ +S+ T + + E+ G Y
Sbjct: 30545 KLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVY 30603
Score = 118 bits (295), Expect = 4e-26
Identities = 143/575 (24%), Positives = 215/575 (37%), Gaps = 93/575 (16%)
Query: 597 YHINLKNEAGEAHASIKVKVVDF------PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSP 650
+ ++ +NE G S K V P PPV P + + + W+PP +DGGS
Sbjct: 17084 FRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSK 17143
Query: 651 ILGYFIERKKKQSSRWMRLNF--DLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMP 708
ILGY +E +K W R N + C ET ++ + +G Y+ R+ AVNA G S P+
Sbjct: 17144 ILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHV 17203
Query: 709 SRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSD 768
P + PP L + D + HI D L +G
Sbjct: 17204 PEPVLVKDRLEPPEL-----ILDANMARE----QHIKVG--DTLRLSAIIKG-------- 17244
Query: 769 ENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAG----ASEPKYY 824
P W ++D K + +T P +K+ +R A G E
Sbjct: 17245 ------VPFPKVTWKKEDRDAPTKARIDVT--PVGSKLEIRNAAHEDGGIYSLTVENPAG 17296
Query: 825 SQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKK---DGAEID 881
S+ + VK ++ K PR L+ + IR K LTWK+ DG +
Sbjct: 17297 SKTVSVKVLVLD-KPGPPRDLEVSEIR--------------KDSCYLTWKEPLDDGGSVI 17341
Query: 882 KNQINIRNSETD---TIIFIRKAERSHSGKY-------------DLQVKVDKFVETASID 925
N + R + + ++SH K+ + Q FVET
Sbjct: 17342 TNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPK-P 17400
Query: 926 IQIIDR---PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVI 982
I+ +D PGPP+ + DV V+L W P DG + ITGY ++ ++ + +W
Sbjct: 17401 IKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIK-F 17459
Query: 983 EHYHRTSATITELVIGNEYYFRVFSENMCGLS-EDATMTKESAVIARDGKIYKNPVYEDF 1041
+ +T L G Y FRV +EN+ GL D T+ E K+ V D
Sbjct: 17460 KTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLPDTTIPIEC-----QEKLVPPSVELDV 17514
Query: 1042 DFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGV 1101
E + AG +RG P P W + I D Y + ++
Sbjct: 17515 KLIEGLVVK---------AGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFS 17565
Query: 1102 CTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
L I+ D G Y N G+ + L V
Sbjct: 17566 SVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 17600
Score = 116 bits (290), Expect = 1e-25
Identities = 185/884 (20%), Positives = 323/884 (36%), Gaps = 156/884 (17%)
Query: 313 NCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDT-TAYCGERVELECEV-SEDDA 370
N DS +TA DE + P + + +D + GE LE ++ +
Sbjct: 24685 NFSEPSDSSGAITARDE-------IDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIP 24737
Query: 371 NVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEY--SVMTTGGQSSAKLSV 428
+V W K+G+E+ +R I+ +K L+++ + D +Y + GG S ++V
Sbjct: 24738 DVVWSKDGKEL-EETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITV 24796
Query: 429 DLK--------PLKIL------------TPLTDQTVNLGKEICLKCEISENIPGKWTKNG 468
+ PLK+ PL D N+ I K E S WT+
Sbjct: 24797 KVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRL---SWTQVS 24853
Query: 469 LPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF---APDAYNVTLPAKVHVID----- 520
VQ + ++ KL+ N +Y+F A + Y + P + +
Sbjct: 24854 TEVQALNY-------KVTKLLPGN-------EYIFRVMAVNKYGIGEPLESGPVTACNPY 24899
Query: 521 -----PPKIILDGLDADNTVTVIA------GNKLRLEIPISGEPPPKAMWSRGDKAIMEG 569
P + + D+ V A G ++ I + W++ +K +
Sbjct: 24900 KPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYI-LEKRDKEGVRWTKCNKKTLTD 24958
Query: 570 SGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGE-AHASIKVKVVDF---PDPPVA 625
R+R + + +A + +GV GE + S+ + D P PP
Sbjct: 24959 L-RLRVTGLTEGHSYEFRVAAENAAGV---------GEPSEPSVFYRACDALYPPGPPSN 25008
Query: 626 PTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETT------F 679
P VT+ + W P YDGG+P+ GY +E K+ + W C T F
Sbjct: 25009 PKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTT-----CTPPTGLQGKQF 25063
Query: 680 EPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTL-----------LTVDS 728
K+ E Y RI A+N+ G+ +P+ V PP + L +
Sbjct: 25064 TVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASA 25123
Query: 729 VTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKD 788
VT++ RP + +G + + TS+ ++ N
Sbjct: 25124 TLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTM--------------LVIDNVT 25169
Query: 789 LIDKTKFTIT--GLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLK 846
D ++ +T FV V+ +++ A P+ + I E K + +
Sbjct: 25170 RFDSGRYNLTLENNSGSKTAFVNVRVLDSPSA--------PVNLT-IREVKKDSVTLSWE 25220
Query: 847 QTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHS 906
I + N ++ + R + K I N + + R S
Sbjct: 25221 PPLIDGGAKITNYIVEKRETTRKAYATITNNCT--KTTFRIENLQEGCSYYFRVLA---S 25275
Query: 907 GKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGY 966
+Y + + + + +++ + P PP V + DV + W P+ DG + ITGY
Sbjct: 25276 NEYGIGLPAE-----TTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGY 25330
Query: 967 TIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVI 1026
++ K S +W T + ATI+ L G EY FRV + N G S+ + VI
Sbjct: 25331 VVEMQTKGSEKWSTCTQ-VKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVP--VI 25387
Query: 1027 ARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVA 1086
ARD +I P P A ++ +G P+ + W K+
Sbjct: 25388 ARDIEI-------------KPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQT 25434
Query: 1087 IVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEI 1130
+ + R + S++ V +L I++ S D GTY N G++ +
Sbjct: 25435 LKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITV 25478
Score = 115 bits (288), Expect = 2e-25
Identities = 180/802 (22%), Positives = 307/802 (38%), Gaps = 107/802 (13%)
Query: 373 KWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKP 432
KW +G EI Y + + +L I+ + D EY + + S ++V L
Sbjct: 17543 KWTTDGSEI--KTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 17600
Query: 433 LKILTPLTDQTVNLG---KEICLKCEISENIPGKWTKNGLPVQESDRLK----VVHKGRI 485
L + P T L + + + + ++ G N + V++ D K VV G
Sbjct: 17601 LDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYI-VEKQDTRKDTWGVVSSGSS 17659
Query: 486 H-KLVIANALTEDEGDYVFAPDAYNV---------TLPAKVHVIDPPKIILDGLDADNTV 535
KL I + + +YVF A N T H PP V
Sbjct: 17660 KTKLKIPHL--QKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSP-----PGKPVV 17712
Query: 536 TVIAGNKLRLE--IPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERD- 592
T I N + +P S P + + + R+ D V + E +
Sbjct: 17713 TDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVNKTPIADLKFRVTGLYEGNT 17772
Query: 593 -DSGVYHINLKNEAGEAHASIKVKV---VDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGG 648
+ V+ NL + + +S +K + P PP+ P + + + + W P DGG
Sbjct: 17773 YEFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGG 17832
Query: 649 SPILGYFIERKKKQSSRWMRLNFD-LCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSM 707
SPILGY +E +K +++W R+N D L ++ F +IEG Y RI A N +G +P
Sbjct: 17833 SPILGYVVECQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRE 17892
Query: 708 PSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAA--GLDGYVLEYCFEGSTSAK 765
+ + + PP + +D +T+R I A G + + EG +
Sbjct: 17893 LAESVIAKDILHPPEV-ELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVR 17951
Query: 766 QSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYS 825
+ + + DLP + + D K+ I+ A N++G ++
Sbjct: 17952 E--KRVDLIQDLPRVELQIKEAVRADHGKYIIS-------------AKNSSG------HA 17990
Query: 826 QPILVKEIIEPPKIRIPRHLKQTYIRRVG--------------EAVNLVIPFQGKPRPEL 871
Q + +++ P ++LK T + + E N ++ ++ KP +
Sbjct: 17991 QGSAIVNVLDRPGPC--QNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYR-KPNQK- 18046
Query: 872 TWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETAS--IDIQII 929
W +++ K I + F AE +V V +ET + + I I
Sbjct: 18047 GWSIVASDVTKRLIKANLLANNEYYFRVCAEN--------KVGVGPTIETKTPILAINPI 18098
Query: 930 DRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTS 989
DRPG P+ + I D V L W P DG + Y +++ K S +W V + + +
Sbjct: 18099 DRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKET 18158
Query: 990 ATITELVIGNEYY-FRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPM 1048
+ + + N+ Y FRV ++N G S+ + E V+ D + P+
Sbjct: 18159 HYMVDRCVENQIYEFRVQTKNEGGESD--WVKTEEVVVKED--------------LQKPV 18202
Query: 1049 FTQPLVNTYAI-AGYNATLNCSVRGNPKPKITWMKNKVA--IVDDPRYRMFSNQGVCTLE 1105
L + AG L VRG P P++ W K+K A + PR ++ +
Sbjct: 18203 LDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFS 18262
Query: 1106 IRKPSPYDGGTYCCKAVNDLGT 1127
+ K DGG Y A N G+
Sbjct: 18263 LTKAKRSDGGKYVVTATNTAGS 18284
Score = 115 bits (288), Expect = 2e-25
Identities = 190/873 (21%), Positives = 328/873 (37%), Gaps = 153/873 (17%)
Query: 324 VTAGDEKCSTELFVREPPIMVTKQLEDT-TAYCGERVELECEV-SEDDANVKWFKNGEEI 381
+TA DE V P I + + +DT + GE +++ ++ + ++W K +E+
Sbjct: 22532 ITARDE-------VDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQEL 22584
Query: 382 IPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTD 441
+R I+ L ++ A + D+ Y + ++V++K L P
Sbjct: 22585 --SNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEG 22642
Query: 442 QTVNLGKEICLKCEISENIPGKWTKNGLPVQE--SDRLKVVHKGR-----IHKLVIANAL 494
V G KC ++ W P+Q+ SD + + + R + +V AN
Sbjct: 22643 PVVISGVT-AEKCTLA------WKP---PLQDGGSDIINYIVERRETSRLVWTVVDANVQ 22692
Query: 495 TED-------EG-DYVF---APDAYNVTLPAKVH--VIDPPKIILDGLDADNTVTVIAGN 541
T EG +Y F A + Y V P + V P ++ D A TV +
Sbjct: 22693 TLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDS 22752
Query: 542 KLRL-EIPISG------------EPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDI 588
+ + E P S W+R K ++ G R+R V +
Sbjct: 22753 MIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLI-GELRLR----------VTGL 22801
Query: 589 AERDDSGVYHINLKNEAGEAHAS---IKVKVVD---FPDPPVAPTVTEVGDDWCIMNWEP 642
E D + ++ +N AG + S K D P PP P V ++ ++W
Sbjct: 22802 IENHDYE-FRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSK 22860
Query: 643 PAYDGGSPILGYFIERKKKQSSRWMRLNFDL-CKETTFEPKKMIEGVAYEVRIFAVNAIG 701
P YDGG I GY +E+ W +T E +K++E Y RI A+N G
Sbjct: 22861 PIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAG 22920
Query: 702 ISKPSMPSRPFVPLAVTSPPTL-----------LTVDSVTDTTVTMRWRPPDHIGAAGLD 750
+ + + P + P + + V ++ RP + +D
Sbjct: 22921 VGEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVD 22980
Query: 751 GYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTIT--GLPTDAKIFV 808
G + + TS+ S ++ N + D K+T+T FV
Sbjct: 22981 GEIRDAAIIDVTSSFTS--------------LVLDNVNRYDSGKYTLTLENSSGTKSAFV 23026
Query: 809 RVKAVNAAGASEPKYYSQPILVKEII----EPPKIRIPRHLKQTYIRRVGEAVNLVIPFQ 864
V+ ++ S P + K+ + EPP + +K + +
Sbjct: 23027 TVRVLDTP--SPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEK------------ 23072
Query: 865 GKPRPELTWKKDGAEID---KNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVET 921
E T K A + KN I + + R + G + +T
Sbjct: 23073 ----REATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYG-------IGLPAQT 23121
Query: 922 ASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV 981
A I++ + P PP + ++DV +V+L+WT P+ DG + I Y ++ K S +W +
Sbjct: 23122 AD-PIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKW-SE 23179
Query: 982 IEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDF 1041
A IT L G EY FRV + N G S+ ++ ++A+D I +
Sbjct: 23180 CARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVP--IVAKDLVIEPD------ 23231
Query: 1042 DFSEAPMFTQPLVNTYAI-AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQG 1100
+P ++Y++ G + + + G PKP ITW K+ + + R + +
Sbjct: 23232 --------VKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLD 23283
Query: 1101 VCTLEIRKPSPYDGGTYCCKAVNDLG--TVEIE 1131
+ TL I++ DGG Y N +G T IE
Sbjct: 23284 LTTLSIKETHKDDGGQYGITVANVVGQKTASIE 23316
Score = 115 bits (287), Expect = 3e-25
Identities = 101/370 (27%), Positives = 158/370 (42%), Gaps = 34/370 (9%)
Query: 266 KGGRVRFVVELAD-----------------PKLEVKWYKNGQEIRPSTKYIFEHKGCQRI 308
+G V FV EL D +E KWY N E++ + KY + ++
Sbjct: 2263 EGAVVEFVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQN 2322
Query: 309 LFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSED 368
L + + D EY +K + +L ++ PI + + L D G+ V+LE +VS +
Sbjct: 2323 LTVKDVTKEDQGEYSFVIDGKKTTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLE 2382
Query: 369 DANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSV 428
W K+G+E+ P R I ++ + H+L+IE TK DA YS S V
Sbjct: 2383 SVEGVWMKDGQEV--QPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRV 2440
Query: 429 DLKPLKILTPLTDQTVNLGKEICLKCEIS--ENIPGKWTKNGLPVQESDRLKVVHKGRIH 486
+ + ++TPL D V G + L+C++S + KW N ++ DR++ + KG
Sbjct: 2441 SVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQ 2500
Query: 487 KLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLE 546
+LVI DEG Y V I I+ GL D T T +E
Sbjct: 2501 RLVINRTHASDEGPYKLIVGRVETNCNLSVEKIK----IIRGL-RDLTCTETQNVVFEVE 2555
Query: 547 IPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG 606
+ SG +W+ DK I + S + + E++ L + +DD G Y AG
Sbjct: 2556 LSHSG---IDVLWNFKDKEI-KPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTF----YAG 2607
Query: 607 EAHASIKVKV 616
E S K+ V
Sbjct: 2608 ENMTSGKLTV 2617
Score = 115 bits (287), Expect = 3e-25
Identities = 246/1161 (21%), Positives = 410/1161 (35%), Gaps = 182/1161 (15%)
Query: 44 GEEQAKQNANSQLSILFIEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWFKGKWMDLA 103
G ++ + Q F+++P+ V G+++TF + ++ + + WF+G +L
Sbjct: 5879 GSDECRAVLTVQEPPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFK---VNWFRGA-RELV 5934
Query: 104 SKAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHEST 163
++ ++T E+++ + +G Y C V+ SC+ L V E
Sbjct: 5935 KGDRCNIYFEDTVA--------ELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEPA 5986
Query: 164 GTTPNIDIRSAFKRSGEGQEDA--GELDFSGLLKRREVKQQEEEP-------QVDVWELL 214
+ S E G L S K+ E + + E+L
Sbjct: 5987 AFLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEIL 6046
Query: 215 KNAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSA--AFAKILDPAYQVDK------ 266
+ K + A QY + E + A L+P Y V +
Sbjct: 6047 NSTK-----RDAGQYSC-----------EIENEAGRDVCGALVSTLEPPYFVTELEPLEA 6090
Query: 267 --GGRVRFVVELAD-PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYY 323
G V ++A P++ V WYK ++RP+ +Y L N + D EY
Sbjct: 6091 AVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYT 6150
Query: 324 VTA------GDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVS-EDDANVKWFK 376
A K + R+ P +QL+D G V L C ++ V W++
Sbjct: 6151 CKAENSIGTASSKTVFRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYR 6210
Query: 377 NGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTG----GQSSAKLSV---- 428
+G ++ ++ V+ + I++ + + +YS + SSA+L+
Sbjct: 6211 DG-VLLRDDENLQTSFVDNVATLKILQ-TDLSHSGQYSCSASNPLGTASSSARLTAREPK 6268
Query: 429 -----DLKPLKILTPLTDQTVNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVVH 481
D+KP+ I V G+ +C ++ P + W+K+ ++ +
Sbjct: 6269 KSPFFDIKPVSI-------DVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITC 6321
Query: 482 KGRIHKLVIANALTEDEGDYV--FAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIA 539
G L I D G Y D A++ V +PPK + L+A
Sbjct: 6322 VGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEPPKFV-KKLEASKVAK--Q 6378
Query: 540 GNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHI 599
G ++LE ISG P K W R D + E S + + L I+ A +DSG Y
Sbjct: 6379 GESIQLECKISGSPEIKVSWFRNDSELHE-SWKYNMSFINSVALLTINEASAEDSGDYIC 6437
Query: 600 NLKNEAGEAHASIKVKVVDFPDPPV-----APTVTEVGDD---WCIMNWEPPAYDGGSPI 651
N G+A S + V PPV +P G D C ++ PP
Sbjct: 6438 EAHNGVGDASCSTALTV---KAPPVFTQKPSPVGALKGSDVILQCEISGTPPFE------ 6488
Query: 652 LGYFIERKKKQSSRWMRL---NFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMP 708
+ + +RK+ ++S+ ++ +FD T+ + E A N +G S
Sbjct: 6489 VVWVKDRKQVRNSKKFKITSKHFD----TSLHILNLEASDVGEYHCKATNEVGSDTCS-- 6542
Query: 709 SRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEG--STSAKQ 766
+ PP + S T T + D L EG S
Sbjct: 6543 ----CSVKFKEPPRFVKKLSDTSTLIG--------------DAVELRAIVEGFQPISVVW 6584
Query: 767 SDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQ 826
+ GE + +E+ ++ D I + K ++K N AG E
Sbjct: 6585 LKDRGEVIRE--SENTRISFIDNIATLQLGSPEASNSGKYICQIK--NDAGMRECS---- 6636
Query: 827 PILVKEIIEPPK-IRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI---DK 882
V ++EP + I P + T G L G P W KDG E+ K
Sbjct: 6637 --AVLTVLEPARIIEKPEPMTVT----TGNPFALECVVTGTPELSAKWFKDGRELSADSK 6690
Query: 883 NQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIV-KIE 941
+ I N + I AE S G Y +VK ++ + + DR PP + K++
Sbjct: 6691 HHITFINKVAS--LKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDRIVPPSFIRKLK 6748
Query: 942 DVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEY 1001
DV N L G + + + + S+ WF E+V G +
Sbjct: 6749 DV---NAIL--------GASVVLECRVSGSAPISVGWF----------QDGNEIVSGPKC 6787
Query: 1002 YFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYED-----FDFSEAPMFTQPLVNT 1056
FSEN+C L+ ++ + + N D E P F Q +
Sbjct: 6788 Q-SSFSENVCTLNLSLLEPSDTGIYT---CVAANVAGSDECSAVLTVQEPPSFEQTPDSV 6843
Query: 1057 YAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGT 1116
+ G + T +RG P K+ W K +V + V LE+ + P + G
Sbjct: 6844 EVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDFVTELELFEVQPLESGD 6903
Query: 1117 YCCKAVNDLGTVEIECKLEVK 1137
Y C ND G+ L VK
Sbjct: 6904 YSCLVTNDAGSASCTTHLFVK 6924
Score = 114 bits (286), Expect = 4e-25
Identities = 235/1151 (20%), Positives = 410/1151 (35%), Gaps = 186/1151 (16%)
Query: 60 FIEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAGKHLQLKETFERH 119
F + P V G +TF + ++ + +KWFKG +L ++ L++
Sbjct: 6836 FEQTPDSVEVLPGMSLTFTSVIRGTPPFK---VKWFKGS-RELVPGESCNISLED----- 6886
Query: 120 SRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSG 179
+ E+++ + + +G+Y C VT SC+ L V E + KR
Sbjct: 6887 ---FVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVKEPA---------TFVKRLA 6934
Query: 180 EGQEDAG-----ELDFSGL-------LKRREVKQQEEEPQVDVWE--LLKNAKPSEYEKI 225
+ + G E ++G +K + Q E + + E + S E
Sbjct: 6935 DFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTILEILESTIEDY 6994
Query: 226 AFQYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVEL--------- 276
A QY L + A +L+P Y ++ V V+
Sbjct: 6995 A-QYSC---------LIENEAGQDICEALVSVLEPPYFIEPLEHVEAVIGEPATLQCKVD 7044
Query: 277 ADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTA----GDEKCS 332
P++ + WYK ++R + Y + K L IN +D EY A G S
Sbjct: 7045 GTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASS 7104
Query: 333 TELFV--REPPIMVTKQLEDTTAYCGERVELECEVS-EDDANVKWFKNGEEIIPGPKSRY 389
L + R+ P ++L+D G V EC ++ + V W+K+G ++ +
Sbjct: 7105 AVLVIKARKLPPFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDG--VLLKDDANL 7162
Query: 390 RIRVEGKKHILIIEGATKADAAEYSVMTTG----GQSSAKLSV---------DLKPLKIL 436
+ L I ++ +Y+ + SSAKL + DLKP+ +
Sbjct: 7163 QTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHEVPPFFDLKPVSV- 7221
Query: 437 TPLTDQTVNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIHKLVIANAL 494
+ LG+ KC ++ P K W K+ ++ K+ L +
Sbjct: 7222 ------DLALGESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVG 7275
Query: 495 TEDEGDYV-FAPD-AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGE 552
D G Y +A + A + A++ V +PP+ I + + V R E I G
Sbjct: 7276 KGDAGQYTCYASNIAGKDSCSAQLGVQEPPRFI---KKLEPSRIVKQDEFTRYECKIGGS 7332
Query: 553 PPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASI 612
P K +W + + I E S + R + L + +DSG Y N AG A +S
Sbjct: 7333 PEIKVLWYKDETEIQE-SSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSST 7391
Query: 613 KVKVVDFPDPPV-----APTVTEVGDD---WCIMNWEPPAYDGGSPILGYFIERKKKQSS 664
+KV +PP+ P T G D C + PP + + ++ ++++ +S
Sbjct: 7392 SLKV---KEPPIFRKKPHPIETLKGADVHLECELQGTPPFH------VSWYKDKRELRSG 7442
Query: 665 RWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV-------PLAV 717
+ + K M E + I V+A I + + V +A+
Sbjct: 7443 K--------------KYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIAL 7488
Query: 718 TSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGS--TSAKQSDENGEAAY 775
+PP + S T V + L+ EG+ S + GE
Sbjct: 7489 KAPPRFVKKLSDISTVVGKEVQ--------------LQTTIEGAEPISVVWFKDKGEIVR 7534
Query: 776 DLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIE 835
+ +++ ++ + I +F+ K ++K N AG E ++E
Sbjct: 7535 E--SDNIWISYSENIATLQFSRVEPANAGKYTCQIK--NDAGMQE------CFATLSVLE 7584
Query: 836 PPKI-RIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI-DKNQINIRNSETD 893
P I P +K T G+ L G P W KDG E+ N+ I
Sbjct: 7585 PATIVEKPESIKVT----TGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKV 7640
Query: 894 TIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIV-KIEDVWGENVALTW 952
+ + I S SG Y +V+ ++ + +Q+ DR PP K+++ G +
Sbjct: 7641 SGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLS----- 7695
Query: 953 TPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCG 1012
G++ + + + S+ WF H + E+ G +Y ++N C
Sbjct: 7696 ------GSSVVMECKVYGSPPISVSWF------HEGN----EISSGRKYQ-TTLTDNTCA 7738
Query: 1013 LSEDATMTKESA--VIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSV 1070
L+ + +S + E P F Q + G N T V
Sbjct: 7739 LTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREPPSFVQKPDPMDVLTGTNVTFTSIV 7798
Query: 1071 RGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEI 1130
+G P ++W K +V R + V LE+ G Y C N+ G
Sbjct: 7799 KGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASC 7858
Query: 1131 ECKLEVKVIAQ 1141
L +K A+
Sbjct: 7859 TTHLYIKAPAK 7869
Score = 110 bits (276), Expect = 6e-24
Identities = 178/830 (21%), Positives = 319/830 (38%), Gaps = 108/830 (13%)
Query: 352 TAYCGERVELECEVS-EDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADA 410
T G + L+ V + + + W K +E+ K ++ GK+ +I+ ++D+
Sbjct: 29058 TIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEK--VSLQYTGKRATAVIKFCDRSDS 29115
Query: 411 AEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIP-----GKWT 465
+Y++ + +SV +K L P TV+ + KC ++ ++P + T
Sbjct: 29116 GKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTVSRVTQE--KCTLAWSLPQEDGGAEIT 29173
Query: 466 KNGLPVQESDRLK-VVHKGRIHKLVIANALTEDEGDYVF---APDAYNVTLPAKVH---- 517
+ +E+ RL V+ +G L +Y+F A + Y +P +
Sbjct: 29174 HYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVA 29233
Query: 518 ----VIDPPKIILDGLDADNTVTVI--------AGNKLRLEIPISGEPPPKAMWSRGDKA 565
I P I + + +I GN++ + + W+R +K
Sbjct: 29234 RNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYL-VDKREKKSLRWTRVNKD 29292
Query: 566 IMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDF-PDPPV 624
+ R++ S + + + +G +E EA I + + P PP
Sbjct: 29293 YVVYDTRLKVTSLMEGCDYQFRVTAVNAAG------NSEPSEASNFISCREPSYTPGPPS 29346
Query: 625 APTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLC-KETTFEPKK 683
AP V + + W P YDGG+ I+GY +E ++K + +W R++ + + T F
Sbjct: 29347 APRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPD 29406
Query: 684 MIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDH 743
+ G Y R+ AVN G+S+ S P+ P L D + T VT+R
Sbjct: 29407 LKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKT-VTIRAGASLR 29465
Query: 744 --IGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLP 801
+ +G V+ + +G A ++ + +Y L IV + D K+TI
Sbjct: 29466 LMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSL----LIVDKVNRYDAGKYTI---- 29517
Query: 802 TDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEP---PKIRIPRHLKQTY-----IRRV 853
+A N +G S +LVK P P +++ + + I +
Sbjct: 29518 ---------EAENQSGKK-----SATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTI 29563
Query: 854 --GEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDL 911
G VN I + + +K + K I T+ + R + G
Sbjct: 29564 DGGAPVNNYI-VEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYG---- 29618
Query: 912 QVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKA 971
+ + ET+ + + + P P +++ DV V L W P DG + +TGY ++
Sbjct: 29619 ---IGEPCETSDA-VLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEAC 29674
Query: 972 DKKSMEWF-------TVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESA 1024
+ W TV+EH T+T L G +Y FR+ ++N G+SE +A
Sbjct: 29675 KAGTERWMKVVTLKPTVLEH------TVTSLNEGEQYLFRIRAQNEKGVSEPRETV--TA 29726
Query: 1025 VIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNK 1084
V +D ++ D S T P + AG L + G P P +W
Sbjct: 29727 VTVQDLRVLPT-----IDLS-----TMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAG 29776
Query: 1085 VAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKL 1134
+ + R + ++ V L IR+ + D G Y + N GT K+
Sbjct: 29777 SKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKV 29826
Score = 109 bits (273), Expect = 1e-23
Identities = 204/910 (22%), Positives = 339/910 (37%), Gaps = 110/910 (12%)
Query: 249 KKSAAFAKILDPAYQVDKGGRVRFVVELAD-PKLEVKWYKNGQEIRPSTKYIFEHKGCQR 307
K+ F + L P +V K V E+ P EV W KN +EIR S KY +
Sbjct: 4952 KEPPTFIRELKPV-EVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVF 5010
Query: 308 ILFINNCQMTDDSEYYVTAGDE----KCSTELFVREPPIMVTKQLEDTTAYCGERVELEC 363
L I C +D EY +E CST + ++EPP + K++E+TT +
Sbjct: 5011 NLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFI-KKIENTTTVLKSSATFQS 5069
Query: 364 EVS-EDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMT---TG 419
V+ ++ W K+ ++I+ + Y I L I + Y+ +G
Sbjct: 5070 TVAGSPPISITWLKD-DQILDEDDNVY-ISFVDSVATLQIRSVDNGHSGRYTCQAKNESG 5127
Query: 420 GQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEI--SENIPGKWTKNGLPVQESDRL 477
+ + +P +I+ V + L+C + + + KW K+G + S
Sbjct: 5128 VERCYAFLLVQEPAQIVEKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYF 5187
Query: 478 KVVHKGRIHKLVIANALTEDEGDYVF--APDAYNVTLPAKVHVID---PPKIILDGLDAD 532
+ + + I + + +D G Y F D + + A + V+D PP D
Sbjct: 5188 SMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQNIPPSFTKKLTKMD 5247
Query: 533 NTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERD 592
+ G+ + +E +SG P A W + K I S + R + S +L ++ E +
Sbjct: 5248 K----VLGSSIHMECKVSGSLPISAQWFKDGKEI-STSAKYRLVCHERSVSLEVNNLELE 5302
Query: 593 DSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPIL 652
D+ Y + N AG+ S + V + P V P + D + E A G+P
Sbjct: 5303 DTANYTCKVSNVAGDDACSGILTVKEPPSFLVKPGRQQAIPDSTV---EFKAILKGTPPF 5359
Query: 653 GYFIERKKKQSSRWMRLNFDLCKETTFEPKKMI--EGVAYEVRIFAVNAIGISKPSMPSR 710
+W + + +L PK I EG + +++V+A SK
Sbjct: 5360 ----------KIKWFKDDVELVS----GPKCFIGLEGSTSFLNLYSVDA---SKTGQ--- 5399
Query: 711 PFVPLAVTSPPTLLTVDSVTDTTVTMRWRPP--------DHIGAAGLDGYVLEYCFEGST 762
VT+ V S + TT+ + PP I AG D LE GS
Sbjct: 5400 --YTCHVTN-----DVGSDSCTTMLLVTEPPKFVKKLEASKIVKAG-DSSRLECKIAGSP 5451
Query: 763 SAKQSDENGEAAYDLPAEDWIVANKDLIDKTK-FTITGLPTDAKIFVRVKAVNAAGASEP 821
+ E ++LPA D ID + L T+ +A N AG++
Sbjct: 5452 EIRVVWFRNE--HELPASD--KYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAGSTS- 5506
Query: 822 KYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI- 880
S ++VK EPP + +T V+L G P E+ W KD ++
Sbjct: 5507 --CSTKVIVK---EPPVFSSFPPIVETL---KNAEVSLECELSGTPPFEVVWYKDKRQLR 5558
Query: 881 DKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKI 940
+ I + T I I + S G+Y + + + +T +++ + PP+ V
Sbjct: 5559 SSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLKE---PPRFV-- 5613
Query: 941 EDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNE 1000
+ +LT G A +I+ A ++W E R S I
Sbjct: 5614 ----SKLNSLTVVA----GEPAELQASIEGAQPIFVQWLKEKEEVIRESENIR------- 5658
Query: 1001 YYFRVFSENMCGL----SEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNT 1056
F EN+ L +E A K I DG + +N E + +
Sbjct: 5659 ---ITFVENVATLQFAKAEPANAGKYICQIKNDGGMREN--MATLMVLEPAVIVEKAGPM 5713
Query: 1057 YAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGT 1116
G TL C V G P+ + W K+ + +++ + +L I D GT
Sbjct: 5714 TVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGT 5773
Query: 1117 YCCKAVNDLG 1126
Y + N++G
Sbjct: 5774 YTFQVQNNVG 5783
Score = 109 bits (272), Expect = 2e-23
Identities = 92/363 (25%), Positives = 161/363 (44%), Gaps = 18/363 (4%)
Query: 269 RVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGD 328
R F E+++P + V+W K+ QE++ + + + + L I + +M+D +Y V AG
Sbjct: 3074 RAMFECEVSEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGG 3133
Query: 329 EKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSR 388
+ +LFV + + ++ +R +E EV+EDD + W+K+G EI + R
Sbjct: 3134 NVSTAKLFVEGRDVRIRSIKKEVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQER 3193
Query: 389 YRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDL-KPLKILTPLTDQTVNLG 447
++ VE + H + I ++DA EY+ + +SS L V+ +P ++L L TV G
Sbjct: 3194 HKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSG 3253
Query: 448 KEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF-A 504
K IS K W K + + K +H G+ + L++ A ED Y A
Sbjct: 3254 KPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEA 3313
Query: 505 PDAYNVTLPAKVHVIDPPKIILDGLD-----------ADNTVTVIAGNKLRLEIPISGEP 553
+ Y V + ++ P+++ + +TVT G R + +SG
Sbjct: 3314 KNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVT-SEGQPARFQCRVSG-T 3371
Query: 554 PPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIK 613
K W DK I + S R + D+ L I A +D G Y N G+ ++
Sbjct: 3372 DLKVSWYSKDKKI-KPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTAN 3430
Query: 614 VKV 616
+ +
Sbjct: 3431 LSL 3433
Score = 108 bits (270), Expect = 3e-23
Identities = 103/437 (23%), Positives = 169/437 (38%), Gaps = 53/437 (12%)
Query: 719 SPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLP 778
SP L D + +V + WRPP G A + GY+LE ++P
Sbjct: 30230 SPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILE------------------RREVP 30271
Query: 779 AEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPK 838
W + + T + GL + + RV A N G S+P +P+ K + PP+
Sbjct: 30272 KAAWYTIDSR-VRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPE 30330
Query: 839 IRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQIN----IRNSETD- 893
P + +V+L +P+ + + G I++ + + +R+++T
Sbjct: 30331 ---PPSNPPEVLDVTKSSVSLS---WSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQI 30384
Query: 894 TIIFIRKAERSHSGKYDLQVKVDKFV---ETASIDIQII-----DRPGPPQIVKIEDVWG 945
T +Y ++ V ET+ ++ D+P P ++I +
Sbjct: 30385 TTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISK 30444
Query: 946 ENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF-TVIEHYHRTSATITELVIGNEYYFR 1004
++V L W P+ DG I GY ++ W + E TI L+ EY FR
Sbjct: 30445 DSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFR 30504
Query: 1005 VFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNA 1064
VF+EN GLS G EAP + + + G A
Sbjct: 30505 VFAENETGLSRPRRTAMSIKTKLTSG--------------EAPGIRKEMKDVTTKLGEAA 30550
Query: 1065 TLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVND 1124
L+C + G P P I W + ++ +Y+M S+ TL + D G Y C A N+
Sbjct: 30551 QLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNE 30610
Query: 1125 LGTVEIECKLEVKVIAQ 1141
+G VE KL ++ Q
Sbjct: 30611 VGEVETSSKLLLQATPQ 30627
Score = 107 bits (268), Expect = 5e-23
Identities = 123/468 (26%), Positives = 198/468 (42%), Gaps = 56/468 (11%)
Query: 196 RREVKQQEEE---PQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSA 252
R + K++ EE + EL K YE++ + +L K + EEKK+
Sbjct: 1998 RSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRK----TKDELLHWTKELTEEEKKAL 2053
Query: 253 AF-AKILDPAYQVDK-----------------------GGRVRFVVELAD-PKLEVKWYK 287
A KI P ++ DK G F V + P E +WYK
Sbjct: 2054 AEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYK 2113
Query: 288 NGQEIRPSTK---YIFEHKGCQRILFINNCQMTDDSEYYV----TAGDEKCSTELFVREP 340
NG +I S + Y E C+ L I + D + V AG+ L V+
Sbjct: 2114 NGVKIERSDRIYWYWPEDNVCE--LVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAK 2171
Query: 341 PIMV-TKQLEDTTAYCGERV-ELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKH 398
++ T++L+D A + + ECE SE VKW+K+G E+ G K YR+ + K H
Sbjct: 2172 QLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGDK--YRMHSDRKVH 2229
Query: 399 ILIIEGATKADAAEYS---VMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCE 455
L I +DA +YS V +++AKL V+ ++ + L D V L+C
Sbjct: 2230 FLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGELECI 2289
Query: 456 IS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPA 514
+S ENI GKW N + ++ + + + + L + + ED+G+Y F D T
Sbjct: 2290 VSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTT--C 2347
Query: 515 KVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIR 574
K+ + P IL GL V G+ ++LE+ +S E + +W + D ++ S R+
Sbjct: 2348 KLKMKPRPIAILQGLSDQK---VCEGDIVQLEVKVSLE-SVEGVWMK-DGQEVQPSDRVH 2402
Query: 575 TESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDP 622
S L+I+ ++D+G Y + + V VD P
Sbjct: 2403 IVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDVITP 2450
Score = 107 bits (268), Expect = 5e-23
Identities = 208/939 (22%), Positives = 343/939 (36%), Gaps = 124/939 (13%)
Query: 239 KRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELAD-PKLEVKWYKNGQEIRPSTK 297
+R+++ E K+A K +V G +F E+ P + +W+K G+EI S K
Sbjct: 3442 ERIEQEIEMEMKAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDK 3501
Query: 298 YIFEHKGCQRILFINNCQMTDDSEYYVTAGDE----KCSTELFVRE--PPIMVTKQLEDT 351
L I Q+ D EY A +E C+ L V E PP +++ +
Sbjct: 3502 CSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPPTFLSRP-KSL 3560
Query: 352 TAYCGERVELECEVSEDDA-NVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADA 410
T + G+ + C V+ W K+G + P P +RI KHIL + T D
Sbjct: 3561 TTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSP--NWRISDAENKHILELSNLTIQDR 3618
Query: 411 AEYSVMTTGGQSS----AKLSVDLKP--LKILTPLTDQTVNLGKEICLKCEISEN--IPG 462
YS + + A+L + KP +K L P+ + K++ L+C++ E+ +
Sbjct: 3619 GVYSCKASNKFGADICQAELIIIDKPHFIKELEPVQSA---INKKVHLECQVDEDRKVTV 3675
Query: 463 KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV--FAPDAYNVTLPAKVHVID 520
W+K+G + K+ + +I L I A +D G YV + +A + + A V V +
Sbjct: 3676 TWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVRE 3735
Query: 521 PPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPD 580
PP + D + ++ G RL + G P + W + +K + E S +R
Sbjct: 3736 PPSFV---KKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKELSE-SNTVRMYFVNS 3791
Query: 581 SSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGD----DWC 636
+ L I + +DSG Y N+ G S ++ + +PP E D
Sbjct: 3792 EAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVI---KEPPSFIKTLEPADIVRGTNA 3848
Query: 637 IMNWEPPAYDGGSPI-LGYFIERKKKQSSRWMRLNFD---LCKETTFEPKKMIEGVAYEV 692
++ E G P + +F ++K+ +SS+ RL +C E F G V
Sbjct: 3849 LLQCE---VSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLE-IFSFNSADVGEYECV 3904
Query: 693 RIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGY 752
V G + P P V L+ + T T+ R + I + G
Sbjct: 3905 VANEVGKCGCMATHLLKEP--PTFVKKVDDLIALGGQT-VTLQAAVRGSEPISVTWMKG- 3960
Query: 753 VLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKA 812
+ K S NG A I+ + + K+T A
Sbjct: 3961 --QEVIREDGKIKMSFSNGVAVL-------IIPDVQISFGGKYTCL-------------A 3998
Query: 813 VNAAGASEPKYYSQPILVKEII--EPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPE 870
N AG+ V E+I EP KI L Q G+ L G P +
Sbjct: 3999 ENEAGSQTS--------VGELIVKEPAKIIERAELIQV---TAGDPATLEYTVAGTPELK 4047
Query: 871 LTWKKDGAEI---DKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQ 927
W KDG + K +I+ +N+ + AE SG+Y ++ + +
Sbjct: 4048 PKWYKDGRPLVASKKYRISFKNNVAQLKFY--SAELHDSGQYTFEISNEVGSSSCETTFT 4105
Query: 928 IIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHR 987
++DR ++A +T P + ++ + G + D K + + +
Sbjct: 4106 VLDR---------------DIAPFFTKPLRNVDSVVNGTC--RLDCKIAGSLPMRVSWFK 4148
Query: 988 TSATITELVIGNEYYFRVFSENMCGLS------EDA---TMTKESAVIARDGKIYKNPVY 1038
I ++ Y F E L DA T ++V ++D
Sbjct: 4149 DGKEIA----ASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSS------- 4197
Query: 1039 EDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSN 1098
E P F + + G L + +G+ I W K +V +
Sbjct: 4198 GALIVQEPPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKE 4257
Query: 1099 QGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1137
+LE+ D GTY CK N G VE L VK
Sbjct: 4258 ALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVK 4296
Score = 107 bits (266), Expect = 8e-23
Identities = 190/903 (21%), Positives = 337/903 (37%), Gaps = 138/903 (15%)
Query: 281 LEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY--YVT--AGDEKCSTELF 336
+++ W K+ +EIRP Y L + D +Y Y + AG + CS +L
Sbjct: 7241 IKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLG 7300
Query: 337 VREPPIMVTKQLEDTTAYCGERVELECEVS-EDDANVKWFKNGEEIIPGPKSRYRIRVEG 395
V+EPP + K E EC++ + V W+K+ EI S++R+
Sbjct: 7301 VQEPPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEI--QESSKFRMSFVD 7358
Query: 396 KKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLK----PLKILTPLTDQTVNLGKEIC 451
+L + + D+ +Y+ SA S LK P+ P +T+ G ++
Sbjct: 7359 SVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPPIFRKKPHPIETLK-GADVH 7417
Query: 452 LKCEISENIPG--KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAP--DA 507
L+CE+ P W K+ ++ + K++ + + + I N D G+Y D
Sbjct: 7418 LECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDV 7477
Query: 508 YNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIM 567
+ T + + PP+ + D ++ + G +++L+ I G P +W + I+
Sbjct: 7478 GSDTCVGSIALKAPPRFVKKLSD----ISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIV 7533
Query: 568 EGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG--EAHASIKV----KVVDFPD 621
S I + +TL E ++G Y +KN+AG E A++ V +V+ P+
Sbjct: 7534 RESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLEPATIVEKPE 7593
Query: 622 PPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEP 681
++ D C + G+P L S++W + +L + ++
Sbjct: 7594 -----SIKVTTGDTCTLE----CTVAGTPEL----------STKWFKDGKELTSDNKYK- 7633
Query: 682 KKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPP 741
+++ ++ + I ++ F + V+D TV PP
Sbjct: 7634 ------ISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTV-----PP 7682
Query: 742 DHI----GAAGLDG--YVLEYCFEGS--TSAKQSDENGEAAYDLPAEDWIVANKDLIDKT 793
GL G V+E GS S E E + + + N
Sbjct: 7683 SFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDN-----TC 7737
Query: 794 KFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRV 853
T+ L A N AG+ E S P+ V+E P ++ P +
Sbjct: 7738 ALTVNMLEESDSGDYTCIATNMAGSDE---CSAPLTVRE--PPSFVQKPDPMDVL----T 7788
Query: 854 GEAVNLVIPFQGKPRPELTWKKDGAEI---DKNQINIRNSETDTIIFIRKAERSHSGKYD 910
G V +G P ++W K +E+ D+ +++ +S + +F + S SG+Y
Sbjct: 7789 GTNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELF--DVDTSQSGEYT 7846
Query: 911 LQVKVD----------------KFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTP 954
V + KFV+ + D I G P I++ +++TW
Sbjct: 7847 CIVSNEAGKASCTTHLYIKAPAKFVKRLN-DYSI--EKGKPLILEGTFTGTPPISVTW-- 7901
Query: 955 PKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLS 1014
K +G I Q+ + + E ++E S+T+ + N Y ++ C
Sbjct: 7902 -KKNG---INVTPSQRCNITTTEKSAILE---IPSSTVEDAGQYNCYIENASGKDSC--- 7951
Query: 1015 EDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNP 1074
SA I + P Y F + L G +A+L C + G P
Sbjct: 7952 --------SAQI-----LILEPPY----------FVKQLEPVKVSVGDSASLQCQLAGTP 7988
Query: 1075 KPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKL 1134
+ ++W K + Y+M V TL + D G Y CKA N +G V L
Sbjct: 7989 EIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFL 8048
Query: 1135 EVK 1137
V+
Sbjct: 8049 TVQ 8051
Score = 107 bits (266), Expect = 8e-23
Identities = 171/808 (21%), Positives = 305/808 (37%), Gaps = 106/808 (13%)
Query: 356 GERVELECEVSEDDA-NVKWFKNGEEIIPGPKSRYRIRVEGKKHI--LIIEGATKADAAE 412
G V+L +S A ++W+K+ +E+ ++ + VE + ++I+ A + ++
Sbjct: 26887 GTSVKLRAGISGKPAPTIEWYKDDKEL----QTNALVCVENTTDLASILIKDADRLNSGC 26942
Query: 413 YSVMTTGGQSSAKLSVDL----KPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNG 468
Y + SA ++ + KP P+ +TV K L +++ K T
Sbjct: 26943 YELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYI 27002
Query: 469 LPVQESDRLK-VVHKGRIHKLVIANALTEDEGDYVF---APDAYNVTLPAKVH-VIDPPK 523
+ +E+ R+ + + + +I +Y+F A + Y + P + V+
Sbjct: 27003 VEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNA 27062
Query: 524 IILDGLDADNTVTVIAGNKLRL----EIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYP 579
+ G VT I N + + I G + DK + G ++ E+
Sbjct: 27063 FVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSL-GWFKVLKETIR 27121
Query: 580 DSSTLVIDIAERDDSGVYHINLKNEAGE---AHASIKVKVVDFPDPPVAPTVTEVGDDW- 635
D+ V + E D Y + N AG+ + S K D DPP P + D
Sbjct: 27122 DTRQKVTGLTENSDYQ-YRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTK 27180
Query: 636 --CIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNF-DLCKETTFEPKKMIEGVAYEV 692
+ W P YDGGS + GY +E ++ + W ++ + T + + GV Y
Sbjct: 27181 SSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYF 27240
Query: 693 RIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGY 752
R+ AVN G +P + P + P + D V +R I AG D
Sbjct: 27241 RVSAVNCAGQGEPIEMNEPVQAKDILEAPEI-------DLDVALR---TSVIAKAGEDVQ 27290
Query: 753 VLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKA 812
VL F+G P W K+L +++I TD+ + +
Sbjct: 27291 VL-IPFKGRPP--------------PTVTWRKDEKNLGSDARYSIEN--TDSSSLLTIPQ 27333
Query: 813 VN-----------AAGASEPKYYSQPILVKEIIEP---PKIRIPRHLKQTYIRRVGE--- 855
V G EPK S + VK + P K+++ +H+ + + + +
Sbjct: 27334 VTRNDTGKYILTIENGVGEPK--SSTVSVKVLDTPAACQKLQV-KHVSRGTVTLLWDPPL 27390
Query: 856 ------AVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKY 909
+N VI + + + TW + + + T F R + G
Sbjct: 27391 IDGGSPIINYVI--EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIG-- 27446
Query: 910 DLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQ 969
+ + ET ++ + P P + + ++D +V L+WT P DG + IT Y ++
Sbjct: 27447 -----IGEPCETTE-PVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVE 27500
Query: 970 KADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARD 1029
+ K W + +++L + FRVF++N GLS+ T+
Sbjct: 27501 RKGKGEQTW-SHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTI---------- 27549
Query: 1030 GKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVD 1089
G I V E E + P G+N L +G PKP I+W+K+ + + +
Sbjct: 27550 GPI---TVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKE 27606
Query: 1090 DPRYRMFSNQGVCTLEIRKPSPYDGGTY 1117
R + TL I+ GG Y
Sbjct: 27607 SEFVRFSKTENKITLSIKNAKKEHGGKY 27634
Score = 106 bits (265), Expect = 1e-22
Identities = 182/920 (19%), Positives = 337/920 (36%), Gaps = 142/920 (15%)
Query: 266 KGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVT 325
+G RF ++ L+V WY ++I+PS + L I D+ Y
Sbjct: 3358 EGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFV 3417
Query: 326 A----GDEKCSTELFVREPPI------------------MVTKQLEDTTAYCGERVELEC 363
A G + L + P ++ +++E G + C
Sbjct: 3418 ASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKAAPVIKRKIEPLEVALGHLAKFTC 3477
Query: 364 EV-SEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIE--GATKADAAEYSVMTTGG 420
E+ S + +WFK G EI K R K+I +E D EY+ +
Sbjct: 3478 EIQSAPNVRFQWFKAGREIYESDKCSIR----SSKYISSLEILRTQVVDCGEYTCKASNE 3533
Query: 421 QSSAKLSVDLK-----PLKILTPLTDQTVNLGKEICLKCEISEN--IPGKWTKNGLPVQE 473
S + L P L+ T +GK C ++ I W K+G +
Sbjct: 3534 YGSVSCTATLTVTEAYPPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSP 3593
Query: 474 SDRLKVVHKGRIHKLVIANALTEDEGDY-VFAPDAYNVTL-PAKVHVIDPPKIILDGLDA 531
S ++ H L ++N +D G Y A + + + A++ +ID P I +
Sbjct: 3594 SPNWRISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDKPHFIKELEPV 3653
Query: 532 DNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSG-RIRTESYPDSSTLVIDIAE 590
+ + K+ LE + + WS+ + + G +I E +TL I +A+
Sbjct: 3654 QSAI----NKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFED--KIATLEIPLAK 3707
Query: 591 RDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYD---G 647
DSG Y NEAG + S V V +PP V +V + ++ E
Sbjct: 3708 LKDSGTYVCTASNEAGSSSCSATVTV---REPP--SFVKKVDPSYLMLPGESARLHCKLK 3762
Query: 648 GSPIL--GYFIERKKKQSSRWMRLNFDLCKETTFE--PKKMIEGVAYEVRIFAVNAIGIS 703
GSP++ +F K+ S +R+ F + E + K+ + +Y AVN +G
Sbjct: 3763 GSPVIQVTWFKNNKELSESNTVRMYF-VNSEAILDITDVKVEDSGSYSCE--AVNDVGSD 3819
Query: 704 KPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTS 763
S + + PP+ + D G+ +
Sbjct: 3820 SCS------TEIVIKEPPSFIKTLEPADIV-------------------------RGTNA 3848
Query: 764 AKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKY 823
Q + +G +++ W K + K+ + + + + + + N+A E
Sbjct: 3849 LLQCEVSGTGPFEI---SWFKDKKQIRSSKKYRL--FSQKSLVCLEIFSFNSADVGE--- 3900
Query: 824 YSQPILVKEIIEPPKIRIPRHLKQ--TYIRRV-------GEAVNLVIPFQGKPRPELTWK 874
+V + LK+ T++++V G+ V L +G +TW
Sbjct: 3901 --YECVVANEVGKCGCMATHLLKEPPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWM 3958
Query: 875 KDGAEI--DKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRP 932
K G E+ + +I + S ++ I + S GKY + + +T+ ++ + +
Sbjct: 3959 K-GQEVIREDGKIKMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKE-- 4015
Query: 933 GPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATI 992
P +I++ E + +T G+ A YT+ + +W+
Sbjct: 4016 -PAKIIE----RAELIQVT------AGDPATLEYTVAGTPELKPKWY-----------KD 4053
Query: 993 TELVIGNEYYFRVFSENMCGLSEDATMTKESA-----VIARDGKIYKNPVYEDFDFSEAP 1047
++ ++ Y F N+ L + +S + G + D AP
Sbjct: 4054 GRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRDIAP 4113
Query: 1048 MFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIR 1107
FT+PL N ++ L+C + G+ +++W K+ I RYR+ +G +LEI
Sbjct: 4114 FFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEII 4173
Query: 1108 KPSPYDGGTYCCKAVNDLGT 1127
+ D G + C+A N +G+
Sbjct: 4174 RVDMNDAGNFTCRATNSVGS 4193
Score = 106 bits (265), Expect = 1e-22
Identities = 117/456 (25%), Positives = 185/456 (40%), Gaps = 83/456 (18%)
Query: 597 YHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFI 656
Y +N + + AS + + D P P VT+V + W PAYDGGS ++GY I
Sbjct: 28916 YALNAAGVSKASEASRPIMAQNPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYII 28975
Query: 657 ERK---KKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIG-ISKPSMPSRPF 712
ERK + RW++ N+ + + F + EG YE R+ A NA G ISK S + P
Sbjct: 28976 ERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPV 29035
Query: 713 VPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGE 772
+PP + VT+R AG D VL+ G K G+
Sbjct: 29036 TCRDEYAPPKAELDARLHGDLVTIR---------AGSD-LVLDAAVGGKPEPKIIWTKGD 29085
Query: 773 AAYDL----------PAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPK 822
DL ++ D D K+T+T NA+G
Sbjct: 29086 KELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLT-------------VKNASGTK--- 29129
Query: 823 YYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTW----KKDGA 878
+ ++VK + P G L + + + L W + GA
Sbjct: 29130 --AVSVMVKVLDSP-----------------GPCGKLTVSRVTQEKCTLAWSLPQEDGGA 29170
Query: 879 EI--------DKNQIN--IRNSETDTIIFIRKAERSHSGKYDLQVK-VDKFVETASIDIQ 927
EI + +++N I E T+ ++ + +Y +V+ V+K+ ++ +
Sbjct: 29171 EITHYIVERRETSRLNWVIVEGECPTLSYV-VTRLIKNNEYIFRVRAVNKYGPGVPVESE 29229
Query: 928 -IIDR-----PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV 981
I+ R P PP I + E++ + WT P+ DG I+ Y + K +KKS+ W V
Sbjct: 29230 PIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRV 29289
Query: 982 IEHY--HRTSATITELVIGNEYYFRVFSENMCGLSE 1015
+ Y + T +T L+ G +Y FRV + N G SE
Sbjct: 29290 NKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSE 29325
Score = 106 bits (264), Expect = 1e-22
Identities = 128/545 (23%), Positives = 211/545 (38%), Gaps = 64/545 (11%)
Query: 620 PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTF 679
P PP P V + + W+PPA DGGSPI GY +E +++ ++ W R+N TT
Sbjct: 15705 PGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTC 15764
Query: 680 E--PKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMR 737
E + E Y R+ AVN G S+PS + + P + +D + +
Sbjct: 15765 ECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVF-IDIGAQDCLVCK 15823
Query: 738 WRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTI 797
I A + +E AK++ ++G +D+P + A + + + I
Sbjct: 15824 AGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDG--VHDIPED----AQLETAENSSVII 15877
Query: 798 TGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAV 857
+P + ++ A + K + + V ++ PPK LK + I R +
Sbjct: 15878 --IPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPK-----DLKVSDITRGSCRL 15930
Query: 858 NLVIP------------FQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIR-KAERS 904
+ +P + + W K + + + ++ F R +AE
Sbjct: 15931 SWKMPDDDGGDRIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAEN- 15989
Query: 905 HSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAIT 964
++ + V+ T + D I P PP +KI + V L+W PPK+DG + +T
Sbjct: 15990 ---RFGIGPPVETIQRTTARDP--IYPPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVT 16044
Query: 965 GYTIQ-----KADKKSMEWFTVIEH-YHRTSATITELVIGNEYYFRVFSENMCGLSEDAT 1018
Y ++ K W + T+ +LV G EY FRV + N G+S+ +
Sbjct: 16045 HYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPSA 16104
Query: 1019 MTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKI 1078
D P + +F E G N + ++G P P +
Sbjct: 16105 TVGPCDCQRPD----MPPSIDLKEFMEVE------------EGTNVNIVAKIKGVPFPTL 16148
Query: 1079 TWMK-------NKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIE 1131
TW K NK ++ D CTL I + D G Y AVN+LGT E
Sbjct: 16149 TWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKE 16208
Query: 1132 CKLEV 1136
+L V
Sbjct: 16209 MRLNV 16213
Score = 105 bits (263), Expect = 2e-22
Identities = 101/375 (26%), Positives = 158/375 (42%), Gaps = 21/375 (5%)
Query: 263 QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 322
+V +G V+ V+++ +E W K+GQE++PS + +L I + D Y
Sbjct: 2366 KVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNY 2425
Query: 323 YVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDD-ANVKWFKNGEEI 381
T ST V + V L+D G + LEC+VS D +VKW+ N E+I
Sbjct: 2426 SFTIPALGLSTSGRVSVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQI 2485
Query: 382 IPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTD 441
P R + V+G K L+I +D Y ++ +++ LSV+ +KI+ L D
Sbjct: 2486 --KPDDRVQAIVKGTKQRLVINRTHASDEGPYKLIVGRVETNCNLSVE--KIKIIRGLRD 2541
Query: 442 QTVNLGKEICLKCEISEN-IPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGD 500
T + + + E+S + I W ++ S + K+ G+I+KL + N + +DEG
Sbjct: 2542 LTCTETQNVVFEVELSHSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGK 2601
Query: 501 YVF--APDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAM 558
Y F + + L I P D TV E+ P K
Sbjct: 2602 YTFYAGENMTSGKLTVAGGAISKPL-------TDQTVAESQEAVFECEV---ANPDSKGE 2651
Query: 559 WSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVD 618
W R K + + IR+ES L+I + DD G Y K + A +KV+ V
Sbjct: 2652 WLRDGKH-LPLTNNIRSESDGHKRRLIIAATKLDDIGEY--TYKVATSKTSAKLKVEAVK 2708
Query: 619 FPDPPVAPTVTEVGD 633
TVTE D
Sbjct: 2709 IKKTLKNLTVTETQD 2723
Score = 103 bits (258), Expect = 7e-22
Identities = 110/456 (24%), Positives = 174/456 (38%), Gaps = 80/456 (17%)
Query: 702 ISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGS 761
+ KP +P+ P + D VT +T++W PP G + + Y+LE
Sbjct: 20073 VGKPGIPTGP------------IKFDEVTAEAMTLKWAPPKDDGGSEITNYILE------ 20114
Query: 762 TSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGA--- 818
K+ N + W+ + KT F +T L + RV A N G
Sbjct: 20115 ---KRDSVNNK---------WVTC-ASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEG 20161
Query: 819 --SEPKYYSQPILVKEIIEPPKIRIPRH----LKQTYIRRVGEAVNLVIPFQGKPRPELT 872
SEP P V + PP I RH L T ++ G + + K R L
Sbjct: 20162 LKSEPIVARHPFDVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLL 20221
Query: 873 WKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETAS--------I 924
WK+ +K I +R+ + + + +Y+ +V +
Sbjct: 20222 WKR----ANKTPIRMRDFKVTGL--------TEGLEYEFRVMAINLAGVGKPSLPSEPVV 20269
Query: 925 DIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIE- 983
+ ID PG P+++ I +V L WT PK DG +TGY ++K D S W
Sbjct: 20270 ALDPIDPPGKPEVINITR---NSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHV 20326
Query: 984 HYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDF 1043
+ + T+T+LV G +Y FR+ ++N G + + E+ +I +D ++
Sbjct: 20327 NVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTET-IICKD------------EY 20373
Query: 1044 SEAPMFTQPLVNTYAI--AGYNATLNC-SVRGNPKPKITWMKNKVAIVDDPRYRMFSNQG 1100
+ P + AG LN S+ G P PK +W K I ++ S
Sbjct: 20374 EAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPT 20433
Query: 1101 VCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
L I+ + D G Y A N GT K+ V
Sbjct: 20434 SSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTV 20469
Score = 102 bits (255), Expect = 2e-21
Identities = 103/389 (26%), Positives = 171/389 (43%), Gaps = 15/389 (3%)
Query: 248 EKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHK-GCQ 306
E+ F K L+ V KG + EL + + +V W K+G+ + I G
Sbjct: 11208 EELPVRFVKTLEEEVTVVKGQPLYLSCEL-NKERDVVWRKDGKIVVEKPGRIVPGVIGLM 11266
Query: 307 RILFINNCQMTDDSEYYVT---AGDEKCSTELFVREP-PIMVTKQLEDTTAYCGERVELE 362
R L IN+ TD Y VT A + +CS+ + V E + K + D
Sbjct: 11267 RALTINDADDTDAGTYTVTVENANNLECSSCVKVVEVIRDWLVKPIRDQHVKPKGTAIFA 11326
Query: 363 CEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQS 422
C++++D N+KWFK +EI P + I +G L I+ A D AEY+V G +
Sbjct: 11327 CDIAKDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGKRY 11386
Query: 423 SAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVH 481
AKL++ + +++L P+ D T+ + EISE +IPG+W G ++ S ++
Sbjct: 11387 PAKLTLGEREVELLKPIEDVTIYEKESASFDAEISEADIPGQWKLKGELLRPSPTCEIKA 11446
Query: 482 KGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGN 541
+G L + + G+ ++ A N A ++ +I LD VTV
Sbjct: 11447 EGGKRFLTLHKVKLDQAGEVLY--QALNAITTA---ILTVKEIELDFAVPLKDVTVPERR 11501
Query: 542 KLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINL 601
+ R E ++ E +WS+G I++ S + + LVI+ ++ DD GVY +
Sbjct: 11502 QARFECVLTRE--ANVIWSKGPD-IIKSSDKFDIIADGKKHILVINDSQFDDEGVYTAEV 11558
Query: 602 KNEAGEAHASIKVKVVDFPDPPVAPTVTE 630
+ + A + + F P TV E
Sbjct: 11559 EGKKTSARLFVTGIRLKFMSPLEDQTVKE 11587
Score = 102 bits (254), Expect = 2e-21
Identities = 85/281 (30%), Positives = 121/281 (43%), Gaps = 16/281 (5%)
Query: 283 VKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPI 342
V W K I+ S K+ G + IL IN+ Q D+ Y +K S LFV +
Sbjct: 11515 VIWSKGPDIIKSSDKFDIIADGKKHILVINDSQFDDEGVYTAEVEGKKTSARLFVTGIRL 11574
Query: 343 MVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILII 402
LED T GE CE+S + +V WFKN ++ I EGK H L +
Sbjct: 11575 KFMSPLEDQTVKEGETATFVCELSHEKMHVVWFKNDAKL--HTSRTVLISSEGKTHKLEM 11632
Query: 403 EGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPG 462
+ T D ++ S+A+L V L D+T EI LKCE+S+++P
Sbjct: 11633 KEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSKDVPV 11692
Query: 463 KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV----FAPDAYNVTLPAKVHV 518
KW K+G + S + + G L I A +D+G+YV NVT+ A++
Sbjct: 11693 KWFKDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIK 11752
Query: 519 IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMW 559
++ P L G V V G EI +S EP W
Sbjct: 11753 VEKP---LYG------VEVFVGETAHFEIELS-EPDVHGQW 11783
Score = 102 bits (254), Expect = 2e-21
Identities = 179/762 (23%), Positives = 289/762 (37%), Gaps = 135/762 (17%)
Query: 340 PPIMVTKQLEDTTAYCGERVELECEV-SEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKH 398
P I++ +Q+ T G+++ +E V + KW K +E++ S +
Sbjct: 18900 PKILMPEQI---TIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTS--SHLAVHKADSSS 18954
Query: 399 ILIIEGATKADAAEYSVMT--TGGQSSAKLSV--------------------DLKPLKIL 436
ILII+ T+ D+ YS+ + G + K+ V D L
Sbjct: 18955 ILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWH 19014
Query: 437 TPLTDQTVNLGKEICLKCEISENIPGKW-TKNGLPVQESDRLKVVHKGRIH--------K 487
PL D N+ I KC++S G W T + S R+ + G+ + +
Sbjct: 19015 IPLEDGGSNITNYIVEKCDVSR---GDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENR 19071
Query: 488 LVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIIL--DGLDADNTVTVIAGNKLRL 545
I+ LT + F + A+V ++ I + D D+D +I
Sbjct: 19072 FGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIG------ 19125
Query: 546 EIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEA 605
I + +W + + + +R+ YP + +++ E + I N+A
Sbjct: 19126 -YLIERKERNSLLWVKANDTL------VRSTEYPCAG--LVEGLEYS----FRIYALNKA 19172
Query: 606 GEAHASIKVKVVDFP---DPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQ 662
G + S + V DPP P V +V + W P +DGGS I+GYF+E K
Sbjct: 19173 GSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLP 19232
Query: 663 SSRWMRLNF--DLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSP 720
+W+R N + + + E Y+ R A A+ IS PS PS P LA P
Sbjct: 19233 GDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVP 19292
Query: 721 P---------TLLTVDSVT----DTTV------TMRWRPPDHIGAAGLDGYVLEYCFEGS 761
P +LLTV + T D TV T+ W+ DG +L+ EG
Sbjct: 19293 PRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKK---------DGTLLKPA-EGI 19342
Query: 762 TSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEP 821
A Q + E + V KD D T T +++K ++ G
Sbjct: 19343 KMAMQRNL-------CTLELFSVNRKDSGDYT-ITAENSSGSKSATIKLKVLDKPGPPAS 19394
Query: 822 ----KYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVG-EAVNLVIPFQGKPRPELTWKKD 876
K YS ++ EPP + G E N ++ + RP W +
Sbjct: 19395 VKINKMYSDRAMLSW--EPP------------LEDGGSEITNYIVDKRETSRPN--WAQV 19438
Query: 877 GAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ 936
A + ++ R + G D F E A I D PG
Sbjct: 19439 SATVPITSCSVEKLIEGHEYQFRICAENKYGVGD-----PVFTEPA-IAKNPYDPPGRCD 19492
Query: 937 IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATI--TE 994
I ++ +++ ++W PP DDG + ITGY ++K + +++ W T + T+ T
Sbjct: 19493 PPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNW-TKVNRKPIIERTLKATG 19551
Query: 995 LVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNP 1036
L G EY FRV + N G + + +K A ARD + P
Sbjct: 19552 LQEGTEYEFRVTAINKAGPGKPSDASK--AAYARDPQYPPGP 19591
Score = 98.6 bits (244), Expect = 3e-20
Identities = 93/361 (25%), Positives = 149/361 (41%), Gaps = 12/361 (3%)
Query: 271 RFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEK 330
+F E++ +W K QEI ++ G + + I + D+++Y A D+
Sbjct: 11858 KFECEVSREPKTFRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKH 11917
Query: 331 CSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYR 390
S +L + + L+D TA E E+S D+ VKWFKN + +
Sbjct: 11918 TSGKLIIEGIRLKFLTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRL--HTTRSVS 11975
Query: 391 IRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEI 450
++ EGK H + + + D ++ V G S AKL+V L D T E+
Sbjct: 11976 MQDEGKTHSITFKDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEV 12035
Query: 451 CLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYN 509
L+CEIS+ + P KW K+G ++ S + G+ L++ AL D G Y D
Sbjct: 12036 ILQCEISKADAPVKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTC--DCGT 12093
Query: 510 VTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWS-RGDKAIME 568
K+ + D ++ L ++V V+ R E IS E A W +G+ +
Sbjct: 12094 DKTSGKLDIEDREIKLVRPL---HSVEVMETETARFETEIS-EDDIHANWKLKGEALLQT 12149
Query: 569 GSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTV 628
I+ E S LV+ D +G N AH +K +V+ P TV
Sbjct: 12150 PDCEIKEEGKIHS--LVLHNCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTV 12207
Query: 629 T 629
T
Sbjct: 12208 T 12208
Score = 97.1 bits (240), Expect = 9e-20
Identities = 126/568 (22%), Positives = 206/568 (36%), Gaps = 75/568 (13%)
Query: 597 YHINLKNEAGEAHASIKVKVV---DFPDPPVAPTVTEVGDDW---CIMNWEPPAYDGGSP 650
+ + +NE G S+ + V D +PP PT V D + W P YDGG+P
Sbjct: 18468 FRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAP 18527
Query: 651 ILGYFIERKKKQSSR-----WMRLNFDL-CKETTFEPKKMIEGVAYEVRIFAVNAIGISK 704
I+GY +E + K + W R N F + E YE R+ A N +GI +
Sbjct: 18528 IIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGR 18587
Query: 705 PSMPSRPFVPLAVTSPPTLLTVDSVTDTTVT-----------MRWRPPDHIG--AAGLDG 751
P+ P + PP + S+ + +R RP + G+D
Sbjct: 18588 PAELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDN 18647
Query: 752 YVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGL-PTDAK-IFVR 809
V + Q D A+ ++ N D K+++T + P K +FV
Sbjct: 18648 VVRK---------GQVDLVDTMAF------LVIPNSTRDDSGKYSLTLVNPAGEKAVFVN 18692
Query: 810 VKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRP 869
V+ ++ G P+ ++ + K H+ G + + +
Sbjct: 18693 VRVLDTPG---------PVSDLKVSDVTKTSC--HVSWAPPENDGGSQVTHYIVEKREAD 18741
Query: 870 ELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQII 929
TW E+ K ++ N + R + G V V + +
Sbjct: 18742 RKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGP-----GVPTDVPKPVLASDPL 18796
Query: 930 DRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGY-TIQKADKKSMEWFTVIEHYHRT 988
P PP+ +++ ++ + L W PP DG A I GY T + +++ + +T
Sbjct: 18797 SEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDL 18856
Query: 989 SATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPM 1048
S +T L G +Y FRV + N G+S + R+ + VYE + P
Sbjct: 18857 SLVVTGLKEGKKYKFRVAARNAVGVS-----------LPREAE----GVYEAKEQLLPPK 18901
Query: 1049 FTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRK 1108
P T AG + V G P P W K + +V + L I+
Sbjct: 18902 ILMPEQITIK-AGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKD 18960
Query: 1109 PSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
+ D G Y A N GT + K+ V
Sbjct: 18961 VTRKDSGYYSLTAENSSGTDTQKIKVVV 18988
Score = 94.4 bits (233), Expect = 6e-19
Identities = 147/655 (22%), Positives = 260/655 (39%), Gaps = 108/655 (16%)
Query: 20 EEPSKEKEAGTTPAKDWTLVETPPGEEQAKQNANSQLSILFIEKPQGGTVKVGEDITFIA 79
E+ SK E + K T E +A + +S+ I + Q TV F
Sbjct: 32816 EKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVI--VTGLQDTTVSSDSVAKFAV 32873
Query: 80 KVKAEDLLRKPTIKWFK--------GKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIK 131
K E +PT W K GK+ K G L++ +T S +YT ++
Sbjct: 32874 KATGEP---RPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVK--- 32927
Query: 132 AKDNFAGNYR--CEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSGEGQEDAGELD 189
N AG+ C++T K D+ + + +++ TP K++ +E + +
Sbjct: 32928 ---NSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQ-------KKAVVQEEISQKAL 32977
Query: 190 FSGLLKRREVKQQE------EEPQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKRLKR 243
S +K E K QE E +V + E +K + + EK IT
Sbjct: 32978 RSEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKTS-------- 33029
Query: 244 MRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHK 303
EE ++ A K +++G R+ +A +VKW NG E+ S +Y +
Sbjct: 33030 QASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGAT-DVKWVLNGVELTNSEEYRYGVS 33088
Query: 304 GCQRILFINNCQMTDDSEYYVTA----GDEKCSTELFVREPPIMVTKQLEDTTAYC---- 355
G + L I D+ + G KC +L ++K+L D A+
Sbjct: 33089 GSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDL-------TLSKELSDAPAFISQPR 33141
Query: 356 ------GERVELECEVS-EDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKA 408
G+ V CE+S E ++WFKN I S I + L I A+ +
Sbjct: 33142 SQNINEGQNVLFTCEISGEPSPEIEWFKNNLPI--SISSNVSISRSRNVYSLEIRNASVS 33199
Query: 409 DAAEYSVMTTG--GQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTK 466
D+ +Y++ GQ SA S+ ++ PL ++ +E+ L+ ++ G ++
Sbjct: 33200 DSGKYTIKAKNFRGQCSATASL------MVLPLVEEP---SREVVLRTSGDTSLQGSFSS 33250
Query: 467 NGLPVQESDR-----------LKVVHKGRIHKLVIANALTEDEGDYVFAPDAY----NVT 511
+ + S + + + + + + + E + ++ N+T
Sbjct: 33251 QSVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMT 33310
Query: 512 ---------LPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRG 562
L A + I PPKI + L +D +++ G L + +GEP P+ WS G
Sbjct: 33311 QLESSTSKMLKAGIRGI-PPKI--EALPSD--ISIDEGKVLTVACAFTGEPTPEVTWSCG 33365
Query: 563 DKAI-MEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKV 616
+ I + GR E+ D +TL+I ++ D G+Y ++L NE G A++ + +
Sbjct: 33366 GRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 33420
Score = 94.0 bits (232), Expect = 7e-19
Identities = 93/416 (22%), Positives = 158/416 (37%), Gaps = 58/416 (13%)
Query: 728 SVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANK 787
+VT +T+ WRPP G A + Y++E E + + +E
Sbjct: 26977 TVTAEKITLLWRPPADDGGAKITHYIVE-----------KRETSRVVWSMVSEH------ 27019
Query: 788 DLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQ 847
+++ T T + + RV+AVN G EP + + P IP K
Sbjct: 27020 --LEECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKI 27077
Query: 848 T-------YIRRVGEAVNLVIPF--QGKPRPELTW---KKDGAEIDKNQINIRNSETDTI 895
T + R + + + + + + + + L W K+ + ++ +D
Sbjct: 27078 TKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQ 27137
Query: 896 IFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPP 955
+ + G + + +F + A ID PGPP ++I D ++ L W+ P
Sbjct: 27138 YRVCAVNAAGQGPFS---EPSEFYKAADP----IDPPGPPAKIRIADSTKSSITLGWSKP 27190
Query: 956 KDDGNAAITGYTIQKADKKSMEWFTVIE--HYHRTSATITELVIGNEYYFRVFSENMCGL 1013
DG +A+TGY ++ + EW TV T ++ L G YYFRV + N G
Sbjct: 27191 VYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQ 27250
Query: 1014 SEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLV---NTYAIAGYNATLNCSV 1070
E M N + D EAP + + A AG + +
Sbjct: 27251 GEPIEM---------------NEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPF 27295
Query: 1071 RGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLG 1126
+G P P +TW K++ + D RY + + L I + + D G Y N +G
Sbjct: 27296 KGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVG 27351
Score = 93.2 bits (230), Expect = 1e-18
Identities = 133/594 (22%), Positives = 227/594 (38%), Gaps = 52/594 (8%)
Query: 60 FIEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAGKHLQLKETFERH 119
F++KP V G ++TF + VK ++ WFKG +L ++ L+++
Sbjct: 7777 FVQKPDPMDVLTGTNVTFTSIVKGTPPF---SVSWFKGS-SELVPGDRCNVSLEDSVA-- 7830
Query: 120 SRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSG 179
E+++ + +G Y C V+ + SC+ L + ++ S K
Sbjct: 7831 ------ELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAKFVKRLNDYSIEKGKP 7884
Query: 180 EGQEDA--GELDFSGLLKRREVKQQEEEPQVDVWELLKNAK---PSEYEKIAFQYGITDL 234
E G S K+ + + + ++ K+A PS + A QY
Sbjct: 7885 LILEGTFTGTPPISVTWKKNGINVTPSQ-RCNITTTEKSAILEIPSSTVEDAGQYNCYIE 7943
Query: 235 RGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELAD-PKLEVKWYKNGQEIR 293
K + + F K L+P +V G +LA P++ V WYK ++R
Sbjct: 7944 NASGKDSCSAQILILEPPYFVKQLEPV-KVSVGDSASLQCQLAGTPEIGVSWYKGDTKLR 8002
Query: 294 PSTKYIFEHKGCQRILFINNCQMTDDSEYYVTA----GDEKCSTELFVREP--PIMVTKQ 347
P+T Y + L N + D EY A G+ ST L V+E P ++Q
Sbjct: 8003 PTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLPPSFSRQ 8062
Query: 348 LEDTTAYCGERVELECEVS-EDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGAT 406
L D G V +C +S + +V W+K+G+ + P + L I
Sbjct: 8063 LRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSP--NVQTSFLDNTATLNIFKTD 8120
Query: 407 KADAAEYSVMTTGGQSSAKLSVDLKPLKILTP------LTDQTVNLGKEICLKCEISENI 460
++ A +YS T SA S L + P L +G+ +C ++
Sbjct: 8121 RSLAGQYSCTATNPIGSASSSARLILTEGKNPPFFDIRLAPVDAVVGESADFECHVTGTQ 8180
Query: 461 PGK--WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV------FAPDAYNVTL 512
P K W K+ ++ + ++ + L + D G Y D+ L
Sbjct: 8181 PIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQL 8240
Query: 513 PAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGR 572
K +I PP TV GN +LE ++G P W + + I S
Sbjct: 8241 NIKERLI-PPSFT---KRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTS-- 8294
Query: 573 IRTESYPDSSTLVIDI--AERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPV 624
E ++TLV+ + A +D+G+Y + N+AG A + + + + PPV
Sbjct: 8295 -NCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPV 8347
Score = 92.0 bits (227), Expect = 3e-18
Identities = 69/216 (31%), Positives = 100/216 (46%), Gaps = 18/216 (8%)
Query: 930 DRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV-IEHYHRT 988
++PG P I V ++ + W PP DG A I Y ++K +KK +W +V E T
Sbjct: 30823 EKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRET 30882
Query: 989 SATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFS-EAP 1047
++ L+ G EY FRV EN+ G SE + +++ P+ D +AP
Sbjct: 30883 VFSVKNLIEGLEYEFRVKCENLGGESEWSEISE--------------PITPKSDVPIQAP 30928
Query: 1048 MFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMK-NKVAIVDDPRYRMFS-NQGVCTLE 1105
F + L N NATL C V G+PKP + W + K I D +YR+ G L
Sbjct: 30929 HFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLI 30988
Query: 1106 IRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVIAQ 1141
I + D Y +A N G+V LEV+V A+
Sbjct: 30989 IASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAK 31024
Score = 89.4 bits (220), Expect = 2e-17
Identities = 139/610 (22%), Positives = 235/610 (38%), Gaps = 87/610 (14%)
Query: 63 KPQGGTVKVGEDITFIAKVKAEDLLRKP--------------TIKWFKGKWMDLASKAGK 108
K G + V E +F+ K ++D+L TI+WFKG +L S
Sbjct: 4194 KDSSGALIVQEPPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGN-KELVSGGSC 4252
Query: 109 HLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPN 168
++ KE E + E+ ++K D+ G Y C+V+ CS +L V E
Sbjct: 4253 YIT-KEALES-----SLELYLVKTSDS--GTYTCKVSNVAGGVECSANLFVKEPATFVEK 4304
Query: 169 IDIRSAFKRSGEGQ-----EDAGELDFSGLLKRREVKQQEEEPQ--VDVWELLKNAKPSE 221
++ K+ Q + + RE+K+ + V+ +L+
Sbjct: 4305 LEPSQLLKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLR------ 4358
Query: 222 YEKIAFQYGITDLRGMLKRLKRMRREE--------KKSAAFAKILDPAYQVDKGGRVRFV 273
GI D + + + K+S F K P +V K V +
Sbjct: 4359 ----LTDVGIEDSGEYMCEAQNEAGSDHCSSIVIVKESPYFTKEFKP-IEVLKEYDVMLL 4413
Query: 274 VELA-DPKLEVKWYKNGQEIRPSTKY---IFEHKGCQRIL-FI------NNCQMTDDSEY 322
E+A P E+ W+K+ +R KY I +H +IL F+ C++T++
Sbjct: 4414 AEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNE--- 4470
Query: 323 YVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSED-DANVKWFKNGEEI 381
G CS + +REPP + K++E T++ G + + V W K+ +EI
Sbjct: 4471 ---VGSSICSARVTLREPPSFI-KKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEI 4526
Query: 382 IPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGG----QSSAKLSVDLKPLKILT 437
R+ E L + G +Y + SA LSV +P I
Sbjct: 4527 T--EDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVK-EPATITE 4583
Query: 438 PLTDQTVNLGKEICLKCEIS--ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALT 495
V G L+ + S + I KW K+G + + K+ + L I +
Sbjct: 4584 EAVSIDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEK 4643
Query: 496 EDEGDYVF--APDAYNVTLPAKVHVID---PPKIILDGLDADNTVTVIAGNKLRLEIPIS 550
+D G+Y F D + A+++V+D PP D+ I G+ + LE ++
Sbjct: 4644 KDSGEYTFEVQNDVGRSSCKARINVLDLIIPPSFTKKLKKMDS----IKGSFIDLECIVA 4699
Query: 551 GEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHA 610
G P W + D+ I S + + + +++ L I E DSG Y + N+AG
Sbjct: 4700 GSHPISIQWFKDDQEI-SASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQC 4758
Query: 611 SIKVKVVDFP 620
S + V + P
Sbjct: 4759 SGHLTVKEPP 4768
Score = 89.4 bits (220), Expect = 2e-17
Identities = 99/438 (22%), Positives = 170/438 (38%), Gaps = 59/438 (13%)
Query: 600 NLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERK 659
N+ ++ + S + +D DPP P + + W P Y GG I Y +E++
Sbjct: 21337 NMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKR 21396
Query: 660 KKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIG-ISKPSMPSRPFVPLAVT 718
+ RW++ NF E F + E AYE R+ A NA G IS PS PS
Sbjct: 21397 DLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDV 21456
Query: 719 SPPTLLTVDSVTDTTVTMRWRPPDHIGA--AGLDGYVLEYCFEGSTSAKQSDENGEAAYD 776
P + VD TV ++ + A +G +E+ +G + G A +
Sbjct: 21457 EAPK-IKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDG------KELEGTAKLE 21509
Query: 777 LPAEDWI--VANKDLI--DKTKFTITGLPTD--AKIFVRVKAVNAAGASEPKYYSQPILV 830
+ D+ + NKD D +T+T AK VK ++ G E P+ V
Sbjct: 21510 IKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPE-----GPLAV 21564
Query: 831 KEIIE--------PPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDK 882
E+ PP + G ++ I Q + L W +E+
Sbjct: 21565 TEVTSEKCVLSWFPP------------LDDGGAKIDHYI-VQKRETSRLAWTNVASEVQV 21611
Query: 883 NQINI-RNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIE 941
++ + + + + IF A + L+ + + P PP+ ++
Sbjct: 21612 TKLKVTKLLKGNEYIFRVMAVNKYGVGEPLE-------SEPVLAVNPYGPPDPPKNPEVT 21664
Query: 942 DVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF-----TVIEHYHRTSATITELV 996
+ +++ + W P DG + I Y +++ DK W T+ + ++ S L
Sbjct: 21665 TITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSG----LT 21720
Query: 997 IGNEYYFRVFSENMCGLS 1014
G+EY FR+ +EN G+S
Sbjct: 21721 EGHEYEFRIMAENAAGIS 21738
Score = 89.0 bits (219), Expect = 2e-17
Identities = 61/198 (30%), Positives = 88/198 (44%), Gaps = 18/198 (9%)
Query: 932 PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSAT 991
P PP+ VK D ++ LTW PPK+DG + I GY +++ + S +W E T
Sbjct: 13588 PDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPVAETKME 13647
Query: 992 ITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAP---M 1048
+T L G Y +RV + N G S+ + T+E + D EAP +
Sbjct: 13648 VTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAV---------------DTQEAPEIFL 13692
Query: 1049 FTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRK 1108
+ L AG L +V G P+PKITW K + + D R + + T+ I
Sbjct: 13693 DVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVD 13752
Query: 1109 PSPYDGGTYCCKAVNDLG 1126
D GTY +AVN G
Sbjct: 13753 SKRSDTGTYIIEAVNVCG 13770
Score = 86.7 bits (213), Expect = 1e-16
Identities = 112/510 (21%), Positives = 197/510 (38%), Gaps = 70/510 (13%)
Query: 648 GSPILGYFIERKKKQSSRWMRLNFDLCKET-TFEPKKMIEGVAYEVRIFAVNAIGISKPS 706
G P+ + R MR N ++ E T K+ + A I A N+ G +K
Sbjct: 26502 GKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAF 26561
Query: 707 MPSRPFVPLAVTSPPT-LLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAK 765
+ V L PPT + + +T+ +VT++W PP + G + + Y+L + TS
Sbjct: 26562 IN---IVVLDRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYIL---LKRETSTA 26615
Query: 766 QSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYS 825
E + +T + L T + R+KA N G S+ S
Sbjct: 26616 VWTEVSAT----------------VARTMMKVMKLTTGEEYQFRIKAENRFGISD-HIDS 26658
Query: 826 QPILVK---EIIEPPKIRIPRHLKQTYI-----RRVGEAVNLVIPF--QGKPRPELTWKK 875
+ VK PP ++ + I V + V+ + + K R + W+K
Sbjct: 26659 ACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQK 26718
Query: 876 DGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETA-----SIDIQIID 930
N++ IR + + S Y+ +V + S + ID
Sbjct: 26719 ------ANKLVIRTTH------FKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAID 26766
Query: 931 RPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV-IEHYHRTS 989
PP+ V+I D+ +V+L+W P DG + ITGY +++ D W + T
Sbjct: 26767 ACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVTETQ 26826
Query: 990 ATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMF 1049
I+ L ++Y FRVF+ N G +++ S V+ P+ D P+
Sbjct: 26827 FIISGLTQNSQYEFRVFARNAVG-----SISNPSEVVG--------PI-TCIDSYGGPVI 26872
Query: 1050 TQPLVNTYAI---AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEI 1106
PL T + AG + L + G P P I W K+ + + + + + ++ I
Sbjct: 26873 DLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILI 26932
Query: 1107 RKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
+ + G Y K N +G+ ++++
Sbjct: 26933 KDADRLNSGCYELKLRNAMGSASATIRVQI 26962
Score = 86.3 bits (212), Expect = 2e-16
Identities = 126/561 (22%), Positives = 206/561 (36%), Gaps = 56/561 (9%)
Query: 91 TIKWFKGKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKF 150
+I+WFK AS+ K F H E+ ++ D+ G Y C T K
Sbjct: 4705 SIQWFKDDQEISASE-------KYKFSFHDNTAFLEISQLEGTDS--GTYTCSATNKAGH 4755
Query: 151 DSCSFDLEVHE---------STGTTPNIDIRSAFKRSGEGQ------EDAGELDFSGLLK 195
+ CS L V E S PN ++ G +D EL
Sbjct: 4756 NQCSGHLTVKEPPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAA-- 4813
Query: 196 RREVKQQEEEPQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFA 255
R V + + ++++ + +++ G + L K+ F
Sbjct: 4814 -RSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLF--------VKEPPQFI 4864
Query: 256 KILDPAYQVDKGGRVRFVVELAD-PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNC 314
K P + G F ++ PK+ V WY +G EI K+ I+
Sbjct: 4865 KKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGA 4924
Query: 315 QMTDDSEYYV----TAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVS-EDD 369
++ + Y AG CS EL V+EPP + ++L+ VELECEV+
Sbjct: 4925 RVENSGTYVCEARNDAGTASCSIELKVKEPPTFI-RELKPVEVVKYSDVELECEVTGTPP 4983
Query: 370 ANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYS--VMTTGGQSSAKLS 427
V W KN EI K Y + L I +D EY V GG S
Sbjct: 4984 FEVTWLKNNREIRSSKK--YTLTDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTR 5041
Query: 428 VDLK-PLKILTPLTDQTVNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGR 484
V LK P + + + T L + ++ + P W K+ + E D + +
Sbjct: 5042 VALKEPPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDNVYISFVDS 5101
Query: 485 IHKLVIANALTEDEGDYVF-APDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKL 543
+ L I + G Y A + V ++ P I ++ +V V + +
Sbjct: 5102 VATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEPAQI---VEKAKSVDVTEKDPM 5158
Query: 544 RLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS-STLVIDIAERDDSGVYHINLK 602
LE ++G P K W + K I+ R + S+ ++ ++ I + DSG Y ++
Sbjct: 5159 TLECVVAGTPELKVKWLKDGKQIV--PSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVE 5216
Query: 603 NEAGEAHASIKVKVVDFPDPP 623
N+ G + ++V+D PP
Sbjct: 5217 NDFGSSSCDAYLRVLDQNIPP 5237
Score = 86.3 bits (212), Expect = 2e-16
Identities = 94/359 (26%), Positives = 158/359 (44%), Gaps = 23/359 (6%)
Query: 285 WYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVT---AGDEKCST-ELFVREP 340
W K+G IR S K+ F G R L I + Q++D EY EK ST +L V E
Sbjct: 11151 WMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEEL 11210
Query: 341 PIMVTKQL-EDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHI 399
P+ K L E+ T G+ + L CE+++ + +V W K+G+ ++ P R V G
Sbjct: 11211 PVRFVKTLEEEVTVVKGQPLYLSCELNK-ERDVVWRKDGKIVVEKP-GRIVPGVIGLMRA 11268
Query: 400 LIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKIL-----TPLTDQTVNLGKEICLKC 454
L I A DA Y+V T ++ + S +K ++++ P+ DQ V C
Sbjct: 11269 LTINDADDTDAGTYTV-TVENANNLECSSCVKVVEVIRDWLVKPIRDQHVKPKGTAIFAC 11327
Query: 455 EISENIPG-KWTK--NGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVT 511
+I+++ P KW K + +P + +D+ +++ G L I NA+ ED +Y A +
Sbjct: 11328 DIAKDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEY--AVEIEGKR 11385
Query: 512 LPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSG 571
PAK+ + + +L ++ VT+ + IS P +G+ ++ S
Sbjct: 11386 YPAKLTLGEREVELLKPIE---DVTIYEKESASFDAEISEADIPGQWKLKGE--LLRPSP 11440
Query: 572 RIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTE 630
++ L + + D +G N A ++K +DF P TV E
Sbjct: 11441 TCEIKAEGGKRFLTLHKVKLDQAGEVLYQALNAITTAILTVKEIELDFAVPLKDVTVPE 11499
Score = 86.3 bits (212), Expect = 2e-16
Identities = 78/292 (26%), Positives = 125/292 (42%), Gaps = 60/292 (20%)
Query: 265 DKGGRVRFV--VELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 322
++GG V++V +E D +V WY +++ S KY ++ IL++ + DD Y
Sbjct: 31580 EEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTY 31639
Query: 323 YVTA----GDEKCSTELFVR---------------------------EPPIMVTKQLEDT 351
G++ ELFV+ E P T L +
Sbjct: 31640 RCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNK 31699
Query: 352 TAYCGERVELECEVS-EDDANVKWFKNGEEIIPGPK-SRYRIRVEGKKHILIIEGATKAD 409
TAY GE V ++ + +V W+K+G++I PG +Y + + L I T D
Sbjct: 31700 TAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDD 31759
Query: 410 AAEYSVMTTG--GQSS--AKLSVDLKPLKILTPLTDQTV-------------NLGKEICL 452
AEY+V+ G+ S AKL+V L P P TD T+ G+ +C
Sbjct: 31760 DAEYTVVARNKYGEDSCKAKLTVTLHP-----PPTDSTLRPMFKRLLANAECQEGQSVCF 31814
Query: 453 KCEISENIPG--KWTKNGLPVQESDRLKVVHKG-RIHKLVIANALTEDEGDY 501
+ +S P KW K+G P+ ++++H+G + L I + L ED G Y
Sbjct: 31815 EIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYY 31866
Score = 85.9 bits (211), Expect = 2e-16
Identities = 91/401 (22%), Positives = 161/401 (40%), Gaps = 47/401 (11%)
Query: 263 QVDKGGRVRFVVELADPKLEVKWYKNGQEI----RPSTKYIFEHKGCQRILFINNCQMTD 318
QV + R E+ + ++ WYK+G EI + KY+ E + +FI+ + +D
Sbjct: 3157 QVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERR--IHRMFISETRQSD 3214
Query: 319 DSEYYVTAGDEKCSTELFVREP-PIMVTKQLEDTTAYCGERVELECEVS-EDDANVKWFK 376
EY AG + S L+V P P V ++L+ T G+ +S + W+K
Sbjct: 3215 AGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYK 3274
Query: 377 NGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAA--------EYSVMTTGGQSSAKL-- 426
+ + G K ++ +G+++ L++ A DAA +Y V TT S ++
Sbjct: 3275 EEQLLSTGFKCKF--LHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPE 3332
Query: 427 ------SVDLKPLKILTPLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKV 479
+ + P I+TPL D + G+ +C +S ++ W ++ S ++
Sbjct: 3333 VVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRM 3392
Query: 480 VHKGRIHKLVIANALTEDEGDYVFAPD--AYNVTLPAKVHVIDPPKIILDGLDAD----- 532
++L IA A EDEG Y F V+ A + + P I+ + ++ +
Sbjct: 3393 TQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEM 3452
Query: 533 ----------NTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSG-RIRTESYPDS 581
+ V G+ + I P + W + + I E IR+ Y
Sbjct: 3453 KAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKY--I 3510
Query: 582 STLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDP 622
S+L I + D G Y NE G + + V + P
Sbjct: 3511 SSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPP 3551
Score = 85.9 bits (211), Expect = 2e-16
Identities = 115/472 (24%), Positives = 174/472 (36%), Gaps = 92/472 (19%)
Query: 693 RIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGY 752
R AVN + KP P+ P L ++ +T ++ W P G A +D Y
Sbjct: 25871 RSVAVNCKVLDKPGPPAGP------------LEINGLTAEKCSLSWGRPQEDGGADIDYY 25918
Query: 753 VLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKA 812
++E E A W + +L T +T L + RV
Sbjct: 25919 IVE-----------KRETSHLA-------WTICEGEL-QMTSCKVTKLLKGNEYIFRVTG 25959
Query: 813 VNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELT 872
VN G EP + + +K + P L+ T + + E++ L RPE
Sbjct: 25960 VNKYGVGEPL---ESVAIKALDPFTVPSPPTSLEITSVTK--ESMTLCWS-----RPE-- 26007
Query: 873 WKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQI---- 928
G+EI I R E +++ ++R ++ YDL+VK E + ++
Sbjct: 26008 -SDGGSEISGYIIERR--EKNSLRWVRVNKKP---VYDLRVKSTGLREGCEYEYRVYAEN 26061
Query: 929 -------------------IDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQ 969
+ P PP KI D + + W P DG A ITGYT++
Sbjct: 26062 AAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVE 26121
Query: 970 KADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARD 1029
+W T I+ T TI+ L G EY FRV S N G S+ + + D
Sbjct: 26122 YKKSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSS--------D 26173
Query: 1030 GKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVD 1089
+I K E ++ M +V AG + T+ RG P P + W K
Sbjct: 26174 PQIAKEREEEPLFDIDSEMRKTLIVK----AGASFTMTVPFRGRPVPNVLWSKPDT---- 26225
Query: 1090 DPRYRMF--SNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVI 1139
D R R + + +L I + D G Y N L + L VKV+
Sbjct: 26226 DLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASL--TLVVKVL 26275
Score = 85.9 bits (211), Expect = 2e-16
Identities = 128/602 (21%), Positives = 222/602 (36%), Gaps = 112/602 (18%)
Query: 581 SSTLVIDIAERDDSGV--YHINLKNEAGEAH----ASIKVKV------VDFPDPPVAPTV 628
S T I++++ + V + + KNE G + I VK VD D P A
Sbjct: 27515 SKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPITVKELIITPEVDLSDIPGAQVT 27574
Query: 629 TEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKET-TFEPKKMIEG 687
+G + ++ E P P + + + + S ++R + K T + + K G
Sbjct: 27575 VRIGHN---VHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHG 27631
Query: 688 VAYEVRI--------FAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWR 739
Y V + + I + PS P P + D + +V + W
Sbjct: 27632 GKYTVILDNAVCRIAVPITVITLGPPSKPKGP------------IRFDEIKADSVILSWD 27679
Query: 740 PPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITG 799
P+ G + Y +E T+ K + + +T F +
Sbjct: 27680 VPEDNGGGEITCYSIEKRETSQTNWKMVCSS-------------------VARTTFKVPN 27720
Query: 800 LPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNL 859
L DA+ RV+A N G S QP++ I+ + RIP G+ V
Sbjct: 27721 LVKDAEYQFRVRAENRYGVS------QPLVSSIIVAKHQFRIPGP--------PGKPVIY 27766
Query: 860 VIPFQGKPRPELTWKKD----GAEIDKNQINIRNSETDTIIFIRKAERSHSGK------- 908
+ G LTW G+E+ ++ E ++I++ + SG+
Sbjct: 27767 NVTSDGM---SLTWDAPVYDGGSEV--TGFHVEKKERNSILWQKVNTSPISGREYRATGL 27821
Query: 909 -----YDLQVKVDKFVETAS--------IDIQIIDRPGPPQIVKIEDVWGENVALTWTPP 955
Y +V + +S + + +D PG P + DV E + L W PP
Sbjct: 27822 VEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYI---DVTRETITLKWNPP 27878
Query: 956 KDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1015
DG + I GY+I+K T+T L G+ Y FR+ + N G
Sbjct: 27879 LRDGGSKIVGYSIEKRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTIS 27938
Query: 1016 DATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPK 1075
+ + ++ RD + P +F P + L+ +G + + V+G P
Sbjct: 27939 PPSQSS-GIIMTRDENV---PPIVEF----GPEYFDGLIIK---SGESLRIKALVQGRPV 27987
Query: 1076 PKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLE 1135
P++TW K+ V I + G +L +R + G Y +A N G+ + E K++
Sbjct: 27988 PRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVK 28047
Query: 1136 VK 1137
V+
Sbjct: 28048 VQ 28049
Score = 85.5 bits (210), Expect = 3e-16
Identities = 203/971 (20%), Positives = 332/971 (34%), Gaps = 208/971 (21%)
Query: 259 DPAYQVDKGGRVRFVVEL-ADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMT 317
D Y + R + + P V W K + T+ E L + +CQ +
Sbjct: 19989 DLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKS 20048
Query: 318 DDSEYYVT----AGDEKCSTELFVREPPIMVTKQL--EDTTAYC------------GERV 359
D +Y +T AG ++ + + V P + T + ++ TA G +
Sbjct: 20049 DAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEI 20108
Query: 360 ELECEVSEDDANVKWFKNGEEIIPGPKSRYRI-----------RVEGKKHILIIEGATKA 408
D N KW + K+ +R+ RV + + EG
Sbjct: 20109 TNYILEKRDSVNNKWVTCASAV---QKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSE 20165
Query: 409 DAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEIC-LKCEISENIPGKWTK- 466
VD++ + TD G I E E W +
Sbjct: 20166 PIVARHPFDVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRA 20225
Query: 467 NGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIIL 526
N P++ D KV LTE +Y F A N+ K + P + L
Sbjct: 20226 NKTPIRMRD-FKVT------------GLTEGL-EYEFRVMAINLAGVGKPSLPSEPVVAL 20271
Query: 527 DGLDAD----------NTVTVI-------AGNKLRLEIPISGEPPPKAMWSRGDKAIMEG 569
D +D N+VT+I G+KL I + P K+ W + +
Sbjct: 20272 DPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKS-WMKANHV---- 20326
Query: 570 SGRIRTESYPDSSTLVIDIAERDDSGVYH--INLKNEAGEAHA-SIKVKVVDFPDPPVAP 626
+ P+ + V D+ E G Y I KN AG A S + + D AP
Sbjct: 20327 -------NVPECAFTVTDLVE---GGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAP 20376
Query: 627 TVTEVGDDWCIMNWEPPAYDG-----GSPIL--GYFIERKKKQSSRWMRLNFDL----CK 675
T+ +P DG G I+ I K S W + D+
Sbjct: 20377 TIV----------LDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDIT 20426
Query: 676 ETTFEPKKMIEGVAYEVR-------IFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDS 728
+ T P + + Y R I A N G + L V PP + + +
Sbjct: 20427 QITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVK---VTVLDVPGPPGPVEISN 20483
Query: 729 VTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKD 788
V+ T+ W PP G + + Y+LE + TS W V ++D
Sbjct: 20484 VSAEKATLTWTPPLEDGGSPIKSYILE---KRETSRLL---------------WTVVSED 20525
Query: 789 LIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQT 848
I + T L + RV AVN G EP S+P+ + + PP
Sbjct: 20526 -IQSCRHVATKLIQGNEYIFRVSAVNHYGKGEP-VQSEPVKMVDRFGPP----------- 20572
Query: 849 YIRRVGEAVNLVIPFQGKPRPELTWKKD----GAEIDKNQINIRNSETDTIIFIRKAERS 904
G + K ++WK+ G+EI + R E ++ ++R +
Sbjct: 20573 -----GPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERR--EKKSLRWVRAIKTP 20625
Query: 905 HSGKYDLQVKVDKFVETASIDIQIIDR-----------------------PGPPQIVKIE 941
S DL+ KV E ++ + ++ PGPP +
Sbjct: 20626 VS---DLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVT 20682
Query: 942 DVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGN-- 999
D ++ +L W P DG ITGY ++ W I+ T+ IT+ V+ +
Sbjct: 20683 DTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAW---IKDTTGTALRITQFVVPDLQ 20739
Query: 1000 ---EYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNT 1056
+Y FR+ + N G+ E A + D +I + + DF+ L T
Sbjct: 20740 TKEKYNFRISAINDAGVGEPAVIP--------DVEIVEREMAPDFELDAE------LRRT 20785
Query: 1057 YAI-AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGG 1115
+ AG + + ++G P P++TW K+ + + + R + + + L I + + YD G
Sbjct: 20786 LVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKN--RANIENTESFTLLIIPECNRYDTG 20843
Query: 1116 TYCCKAVNDLG 1126
+ N G
Sbjct: 20844 KFVMTIENPAG 20854
Score = 85.1 bits (209), Expect = 3e-16
Identities = 128/595 (21%), Positives = 233/595 (39%), Gaps = 66/595 (11%)
Query: 59 LFIEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAGKHLQLKETFER 118
+F +KP G D+ ++ + W K + K ++ + F+
Sbjct: 6459 VFTQKPSPVGALKGSDVILQCEISGTPPFE---VVWVKDR---------KQVRNSKKFKI 6506
Query: 119 HSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLE-------VHESTGTTPNIDI 171
S+ + + I+ + + G Y C+ T + D+CS ++ V + + T+ I
Sbjct: 6507 TSKHFDTSLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPPRFVKKLSDTSTLIGD 6566
Query: 172 RSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLKNAKPSEYEKIA-FQYG 230
+ EG + + L R EV ++ E N + S + IA Q G
Sbjct: 6567 AVELRAIVEGFQ---PISVVWLKDRGEVIRESE-----------NTRISFIDNIATLQLG 6612
Query: 231 ITDLRGMLKRLKRMRREE--KKSAAFAKILDPAYQVDKGGRVRFV---------VELADP 279
+ K + +++ + ++ +A +L+PA ++K + V P
Sbjct: 6613 SPEASNSGKYICQIKNDAGMRECSAVLTVLEPARIIEKPEPMTVTTGNPFALECVVTGTP 6672
Query: 280 KLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYV----TAGDEKCSTEL 335
+L KW+K+G+E+ +K+ L I +M+D Y + G C+ +
Sbjct: 6673 ELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSV 6732
Query: 336 FVRE---PPIMVTKQLEDTTAYCGERVELECEVS-EDDANVKWFKNGEEIIPGPK--SRY 389
V + PP + K L+D A G V LEC VS +V WF++G EI+ GPK S +
Sbjct: 6733 HVSDRIVPPSFIRK-LKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSF 6791
Query: 390 RIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKE 449
V L+ T + + + SA L+V P TP + + + G
Sbjct: 6792 SENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPPSFEQTPDSVEVLP-GMS 6850
Query: 450 ICLKCEISENIP--GKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY--VFAP 505
+ I P KW K + + + + + +L + + GDY +
Sbjct: 6851 LTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTN 6910
Query: 506 DAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKA 565
DA + + + V +P + D +V G+ + LE +G PP W + D+
Sbjct: 6911 DAGSASCTTHLFVKEPATFVKRLAD----FSVETGSPIVLEATYTGTPPISVSWIK-DEY 6965
Query: 566 IMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFP 620
++ S R S+ L I + +D Y ++NEAG+ V V++ P
Sbjct: 6966 LISQSERCSITMTEKSTILEILESTIEDYAQYSCLIENEAGQDICEALVSVLEPP 7020
Score = 85.1 bits (209), Expect = 3e-16
Identities = 105/480 (21%), Positives = 179/480 (37%), Gaps = 70/480 (14%)
Query: 672 DLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTD 731
D C+E + A E I +N I + KP P+ P + +D VT
Sbjct: 22209 DACREDVGHYVVKLTNSAGEA-IETLNVIVLDKPGPPTGP------------VKMDEVTA 22255
Query: 732 TTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLID 791
++T+ W PP + G + ++ Y++E D W + + +
Sbjct: 22256 DSITLSWGPPKYDGGSSINNYIVE------------------KRDTSTTTWQIVSAT-VA 22296
Query: 792 KTKFTITGLPTDAKIFVRVKAVNAAGAS-----EPKYYSQPILVKEIIEPPKIRIPRH-- 844
+T L T + R+ A N G S EP P V P + +
Sbjct: 22297 RTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDS 22356
Query: 845 LKQTYIRRVGEAVNLVIPF--QGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAE 902
++ + + + + VI + + K R + W K ++K I +T + + E
Sbjct: 22357 MEVQWNEPISDGGSRVIGYHLERKERNSILWVK----LNKTPIPQTKFKTTGLEEGVEYE 22412
Query: 903 RSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAA 962
S + + + V + D PG P+ + + +V L W P DG +
Sbjct: 22413 FRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIIVTR---NSVTLQWKKPTYDGGSK 22469
Query: 963 ITGYTIQKADKKSMEWFTV-IEHYHRTSATITELVIGNEYYFRVFSENMCGL-SEDATMT 1020
ITGY ++K + W + T +T LV + Y FRV + N G+ SE + T
Sbjct: 22470 ITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSEST 22529
Query: 1021 KESAVIARDG----KIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKP 1076
A+ ARD +I +P Y+D AG + ++ + G P P
Sbjct: 22530 --GAITARDEVDPPRISMDPKYKD--------------TIVVHAGESFKVDADIYGKPIP 22573
Query: 1077 KITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
I W+K + + R + S +L ++ D G Y KA N G + ++V
Sbjct: 22574 TIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKV 22633
Score = 85.1 bits (209), Expect = 3e-16
Identities = 100/435 (22%), Positives = 171/435 (39%), Gaps = 65/435 (14%)
Query: 720 PPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPA 779
PP + +D V+ ++T+ W PP++ G + Y++E ST+
Sbjct: 25490 PPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTT---------------- 25533
Query: 780 EDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPP-- 837
W + ++ + +T I L T ++ RV A N G S S ++ + PP
Sbjct: 25534 --WHIVSQ-AVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSE-SSAVVAEYPFSPPGP 25589
Query: 838 --KIRIPRHLKQTYIRR----VGEAVNLVIPF--QGKPRPELTWKKDGAEIDKNQINIRN 889
++ K T + V + + VI + + K R + W K N+I I
Sbjct: 25590 PGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSK------ANKILI-- 25641
Query: 890 SETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQII------DRPGPPQIVKIEDV 943
DT + + + +Y + + + S + + D PG P++ I
Sbjct: 25642 --ADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTNITR- 25698
Query: 944 WGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV-IEHYHRTSATITELVIGNEYY 1002
++V+L W+ P DG A ITGY +++ + W + T +TEL Y
Sbjct: 25699 --KSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFEVTELTEDQRYE 25756
Query: 1003 FRVFSENMC-GLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAG 1061
FRVF+ N +SE + T +I +D + V D F + + AG
Sbjct: 25757 FRVFARNAADSVSEPSEST--GPIIVKDD-VEPPRVMMDVKFRDVIVVK---------AG 25804
Query: 1062 YNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKA 1121
+N + G P P I+W K+ + I + R + S L ++ D G Y
Sbjct: 25805 EVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTL 25864
Query: 1122 VNDLGT--VEIECKL 1134
N GT V + CK+
Sbjct: 25865 KNVAGTRSVAVNCKV 25879
Score = 84.0 bits (206), Expect = 8e-16
Identities = 100/460 (21%), Positives = 169/460 (36%), Gaps = 78/460 (16%)
Query: 697 VNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEY 756
+ + + P P PF + + ++ W P G + + Y++E
Sbjct: 18984 IKVVVMDAPGPPQPPF------------DISDIDADACSLSWHIPLEDGGSNITNYIVEK 19031
Query: 757 CFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAA 816
C D+ DW+ A + KT + L + RV+A N
Sbjct: 19032 C------------------DVSRGDWVTALAS-VTKTSCRVGKLIPGQEYIFRVRAENRF 19072
Query: 817 GASEPKYYSQPILVKEI-----IEPPKIRIPRHLKQ----TYIRRVGEAVNLVIPF--QG 865
G SEP + P +V + EP R+ + K + R + + +I + +
Sbjct: 19073 GISEP--LTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIER 19130
Query: 866 KPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERS------HSGKYDLQVKVDKFV 919
K R L W K N +R++E + E S + K ++V
Sbjct: 19131 KERNSLLWVK------ANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYV 19184
Query: 920 ETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF 979
TA + + D PG P+++ DV V+L W PK DG + I GY ++ +W
Sbjct: 19185 -TARMPV---DPPGKPEVI---DVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWV 19237
Query: 980 ---TVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNP 1036
T + T T L +Y FR + +S + + ++A + P
Sbjct: 19238 RCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENV-----P 19292
Query: 1037 VYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMF 1096
D + + T AG N L+ +V G P P ++W K+ + +M
Sbjct: 19293 PRIDLSVAMKSLLTVK-------AGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMA 19345
Query: 1097 SNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
+ +CTLE+ + D G Y A N G+ KL+V
Sbjct: 19346 MQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKV 19385
Score = 82.8 bits (203), Expect = 2e-15
Identities = 59/194 (30%), Positives = 92/194 (47%), Gaps = 21/194 (10%)
Query: 547 IPISGEPPPKAMWSRGDKAIMEGSGRIRTE-------SYPDSSTLVIDIAERDDSGVYHI 599
+ + EPP + ++E R+ T + PD + V D+ E + + +
Sbjct: 14200 VDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQ-FQV 14258
Query: 600 NLKNEAGEAHASIKVKVVDFPDPPVAPT------VTEVGDDWCIMNWEPPAYDGGSPILG 653
+NEAG H S +++ DP P+ VT+ G + W+PP +GGSPI+G
Sbjct: 14259 RAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIG 14318
Query: 654 YFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVA----YEVRIFAVNAIGISKPSMPS 709
Y +E + +WMR+N K+ F K+ EGV Y +R+ AVNAIG+S+PS S
Sbjct: 14319 YHVEMCPVGTEKWMRVNSRPIKDLKF---KVEEGVVPDKEYVLRVRAVNAIGVSEPSEIS 14375
Query: 710 RPFVPLAVTSPPTL 723
V PT+
Sbjct: 14376 ENVVAKDPDCKPTI 14389
Score = 82.4 bits (202), Expect = 2e-15
Identities = 137/626 (21%), Positives = 234/626 (37%), Gaps = 79/626 (12%)
Query: 27 EAGTTPAKDWTLVETPPGEEQAKQNANSQLSILFIEKPQGGTV-KVGEDITFIAKVKAED 85
+ GT +K V+ PP FI+KP V + G+ TF ++
Sbjct: 4845 DVGTATSKATLFVKEPPQ---------------FIKKPSPVLVLRNGQSTTFECQITGTP 4889
Query: 86 LLRKPTIKWF-KGKWMDLASKAG-KHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCE 143
+R + W+ G + K G + TF QI A+ +G Y CE
Sbjct: 4890 KIR---VSWYLDGNEITAIQKHGISFIDGLATF-----------QISGARVENSGTYVCE 4935
Query: 144 VTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSGEGQE----DAGELDFSGLLKRREV 199
SCS +L+V E + K S E + + L RE+
Sbjct: 4936 ARNDAGTASCSIELKVKEPPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREI 4995
Query: 200 KQQEE---EPQVDVWEL-LKNAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFA 255
+ ++ +V V+ L + PS+ + +Q +++ G R+ +E S F
Sbjct: 4996 RSSKKYTLTDRVSVFNLHITKCDPSDTGE--YQCIVSNEGGSCSCSTRVALKEPPS--FI 5051
Query: 256 KILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQ 315
K ++ V K P + + W K+ Q + L I +
Sbjct: 5052 KKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDNVYISFVDSVATLQIRSVD 5111
Query: 316 MTDDSEYYVTA----GDEKCSTELFVREPPIMVTK-QLEDTTAYCGERVELECEVS-EDD 369
Y A G E+C L V+EP +V K + D T + + LEC V+ +
Sbjct: 5112 NGHSGRYTCQAKNESGVERCYAFLLVQEPAQIVEKAKSVDVTE--KDPMTLECVVAGTPE 5169
Query: 370 ANVKWFKNGEEIIPGPKSRY-RIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSV 428
VKW K+G++I+P SRY + E I+ K D+ +Y+ S+
Sbjct: 5170 LKVKWLKDGKQIVP---SRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDA 5226
Query: 429 DLK------PLKILTPLTDQTVNLGKEICLKCEISENIP--GKWTKNGLPVQESDRLKVV 480
L+ P LT LG I ++C++S ++P +W K+G + S + ++V
Sbjct: 5227 YLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLV 5286
Query: 481 HKGRIHKLVIANALTEDEGDY------VFAPDAYNVTLPAKVHVIDPPKIILDGLDADNT 534
R L + N ED +Y V DA + L K +PP ++
Sbjct: 5287 CHERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVK----EPPSFLV----KPGR 5338
Query: 535 VTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDS 594
I + + + + G PP K W + D ++ G + +S L + + +
Sbjct: 5339 QQAIPDSTVEFKAILKGTPPFKIKWFKDDVELVSGP-KCFIGLEGSTSFLNLYSVDASKT 5397
Query: 595 GVYHINLKNEAGEAHASIKVKVVDFP 620
G Y ++ N+ G + + V + P
Sbjct: 5398 GQYTCHVTNDVGSDSCTTMLLVTEPP 5423
Score = 80.9 bits (198), Expect = 6e-15
Identities = 77/261 (29%), Positives = 107/261 (40%), Gaps = 22/261 (8%)
Query: 464 WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPD--AYNVTLPAKVHVIDP 521
W K+G V+ SDRL + + L + ++ D G Y + + T V VI
Sbjct: 14420 WHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGL 14479
Query: 522 PKIILDGLDADNTVTVIAGNKLRLEIP--ISGEPPPKAMWSRGDKA------IMEGSGRI 573
P D +D T + KL E P G P + R + +M G ++
Sbjct: 14480 PGPCKDIKASDITK---SSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKL 14536
Query: 574 R---TESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTE 630
+ P+ A G +I LKN I PDPPV V
Sbjct: 14537 SWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPV------IAQDPKQPPDPPVDVEVHN 14590
Query: 631 VGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAY 690
+ + W+PP YDGGS I+GY IE+ K RW R N L T+ K + EG Y
Sbjct: 14591 PTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEY 14650
Query: 691 EVRIFAVNAIGISKPSMPSRP 711
+ R+ A NA GIS+PS + P
Sbjct: 14651 QFRVRAENAAGISEPSRATPP 14671
Score = 77.8 bits (190), Expect = 5e-14
Identities = 104/452 (23%), Positives = 164/452 (36%), Gaps = 62/452 (13%)
Query: 697 VNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEY 756
++ I + KP P P + D V+ V + W PP + G + Y++E
Sbjct: 24397 LSVIVLEKPGPPVGP------------VRFDEVSADFVVISWEPPAYTGGCQISNYIVE- 24443
Query: 757 CFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAA 816
D W + + + +T IT L T + R+ A N
Sbjct: 24444 -----------------KRDTTTTTWHMVSAT-VARTTIKITKLKTGTEYQFRIFAENRY 24485
Query: 817 GASEPKYYSQPILV----KEIIEPPKIRIPRHLKQTYIRRVGEAVN------LVIPFQGK 866
G S P S+ ++V KE P + K + + E VN + + K
Sbjct: 24486 GKSAP-LDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQK 24544
Query: 867 PRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDI 926
+ + W K ++K I +T + + E S + + + V +
Sbjct: 24545 EKNSILWVK----LNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVAR 24600
Query: 927 QIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV-IEHY 985
D PG P+ + I NV L W P DG + ITGY ++K D W +
Sbjct: 24601 DPCDPPGRPEAIVITR---NNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNV 24657
Query: 986 HRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSE 1045
T T++ LV Y FRV + N G + + A+ ARD N +
Sbjct: 24658 LETEFTVSGLVEDQRYEFRVIARNAAGNFSEPS-DSSGAITARDEIDAPNASLD------ 24710
Query: 1046 APMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDD-PRYRMFSNQGVCTL 1104
P + +V AG L +RG P P + W K+ + + R + S TL
Sbjct: 24711 -PKYKDVIV---VHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTL 24766
Query: 1105 EIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
++ DGG Y K N GT I ++V
Sbjct: 24767 VVKDCIRTDGGQYILKLSNVGGTKSIPITVKV 24798
Score = 77.4 bits (189), Expect = 7e-14
Identities = 118/571 (20%), Positives = 224/571 (39%), Gaps = 53/571 (9%)
Query: 92 IKWFKGKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFD 151
+ W+K K + L+ + ++ S+ + + I+ + G Y C+ + D
Sbjct: 5548 VVWYKDK---------RQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGSD 5598
Query: 152 SCSFDLEVHESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVW 211
+C +++ E ++ S +GE E ++ + + + +K++EE V
Sbjct: 5599 TCVCTVKLKEPPRFVSKLN--SLTVVAGEPAELQASIEGAQPIFVQWLKEKEE-----VI 5651
Query: 212 ELLKNAKPSEYEKIA-FQYGITDLRGMLKRLKRMRRE--EKKSAAFAKILDPAYQVDKGG 268
+N + + E +A Q+ + K + +++ + +++ A +L+PA V+K G
Sbjct: 5652 RESENIRITFVENVATLQFAKAEPANAGKYICQIKNDGGMRENMATLMVLEPAVIVEKAG 5711
Query: 269 RVRFVV---------ELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDD 319
+ V P+L V+WYK+G+ + S K+ F L I + + D
Sbjct: 5712 PMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDA 5771
Query: 320 SEYYV----TAGDEKCSTELFV--REPPIMVTKQLEDTTAYCGERVELECEVS-EDDANV 372
Y G C+ + V R P T++L++T G LEC+V+ +V
Sbjct: 5772 GTYTFQVQNNVGKSSCTAVVDVSDRAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISV 5831
Query: 373 KWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSS----AKLSV 428
WF +I+ G K Y+ L + +D Y+ + S A L+V
Sbjct: 5832 AWFHEKTKIVSGAK--YQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTV 5889
Query: 429 DLKPLKILTPLTDQTVNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIH 486
P + P V GK + I P K W + + + DR + + +
Sbjct: 5890 QEPPSFVKEP-EPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDTVA 5948
Query: 487 KLVIANALTEDEGDY--VFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLR 544
+L + N G+Y V + +A + ++ V +P + D +V G +
Sbjct: 5949 ELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEPAAFLKRLSDH----SVEPGKSII 6004
Query: 545 LEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNE 604
LE +G P W + D + S + + + L I + + D+G Y ++NE
Sbjct: 6005 LESTYTGTLPISVTWKK-DGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIENE 6063
Query: 605 AGEAHASIKVKVVDFP--DPPVAPTVTEVGD 633
AG V ++ P + P VGD
Sbjct: 6064 AGRDVCGALVSTLEPPYFVTELEPLEAAVGD 6094
Score = 77.4 bits (189), Expect = 7e-14
Identities = 50/197 (25%), Positives = 94/197 (47%), Gaps = 14/197 (7%)
Query: 251 SAAFAKILDPAYQ-------VDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHK 303
++A +++PA++ + +G + + P ++ +W++NG+ ++P ++ E +
Sbjct: 8736 ASAKLTVIEPAWERHLQDVTLKEGQTCTMTCQFSVPNVKSEWFRNGRILKPQGRHKTEVE 8795
Query: 304 GCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELEC 363
L I + + D +Y D + S EL + PI TK++++ + EC
Sbjct: 8796 HKVHKLTIADVRAEDQGQYTCKYEDLETSAELRIEAEPIQFTKRIQNIVVSEHQSATFEC 8855
Query: 364 EVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTT----- 418
EVS DDA V W+K E+ K Y R +G+ H + I T D YSV+
Sbjct: 8856 EVSFDDAIVTWYKGPTELTESQK--YNFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRG 8913
Query: 419 GGQSSAKLSVDLKPLKI 435
+S+A+L + K +K+
Sbjct: 8914 EARSTAELYLTTKEIKL 8930
Score = 77.4 bits (189), Expect = 7e-14
Identities = 102/462 (22%), Positives = 169/462 (36%), Gaps = 81/462 (17%)
Query: 696 AVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLE 755
++ + + KP P P + D V+ ++T+ W PP + G + Y+++
Sbjct: 23314 SIEIVTLDKPDPPKGP------------VKFDDVSAESITLSWNPPLYTGGCQITNYIVQ 23361
Query: 756 YCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNA 815
D W V + + +T +T L T + R+ A N
Sbjct: 23362 ------------------KRDTTTTVWDVVSAT-VARTTLKVTKLKTGTEYQFRIFAENR 23402
Query: 816 AGASEPKYYSQPILVKEIIE---PPKIRIPRHL-KQTYIRRVGEAVN------LVIPFQG 865
G S S PI+ + + PP + K + + + E VN + +
Sbjct: 23403 YGQSFA-LESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLER 23461
Query: 866 KPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSG-KYDLQVKVDKFVETAS- 923
K R + W K ++K I+ DT KA+ G +Y+ +V + V
Sbjct: 23462 KERNSILWTK----VNKTIIH------DTQF---KAQNLEEGIEYEFRVYAENIVGVGKA 23508
Query: 924 -------IDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSM 976
+ D PG P+ + ++ + L WT P DG + ITGY ++K D
Sbjct: 23509 SKNSECYVARDPCDPPGTPEPIMVKR---NEITLQWTKPVYDGGSMITGYIVEKRDLPDG 23565
Query: 977 EWFTV-IEHYHRTSATITELVIGNEYYFRVFSENMCG-LSEDATMTKESAVIARDGKIYK 1034
W + T T++ L Y FRV ++N G +S+ + T G I
Sbjct: 23566 RWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDST---------GPITA 23616
Query: 1035 NPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYR 1094
E S P F +V AG L V G P P I W++ I + R
Sbjct: 23617 KDEVELPRISMDPKFRDTIVVN---AGETFRLEADVHGKPLPTIEWLRGDKEIEESARCE 23673
Query: 1095 MFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
+ + L ++ DGG Y +A N G+ ++V
Sbjct: 23674 IKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKV 23715
Score = 77.0 bits (188), Expect = 9e-14
Identities = 106/469 (22%), Positives = 169/469 (36%), Gaps = 97/469 (20%)
Query: 697 VNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEY 756
+ I + KP P+ P + +D + T++T+ W PP+ G A L GYV+E
Sbjct: 29824 IKVIILDKPGPPTGP------------IKIDEIDATSITISWEPPELDGGAPLSGYVVEQ 29871
Query: 757 CFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAA 816
D W+ ++ + ++ F T L + RV A N
Sbjct: 29872 ------------------RDAHRPGWLPVSES-VTRSTFKFTRLTEGNEYVFRVAATNRF 29912
Query: 817 GASEPKYYSQPILVKEIIE-PPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTW-- 873
G L E+IE IRIP G L I + LTW
Sbjct: 29913 GIGS-------YLQSEVIECRSSIRIP-----------GPPETLQIFDVSRDGMTLTWYP 29954
Query: 874 -KKDGAE------IDKNQINIR-----NSETDTIIFIRKAERSHSGKYDLQVKVDKFVET 921
+ DG +++ ++ N T+ R + +Y+ +V +
Sbjct: 29955 PEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGS 30014
Query: 922 AS--------IDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADK 973
+ + I PG PQ ++ D +V+L W+ P+D+G + +TGY I+
Sbjct: 30015 GKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKV 30074
Query: 974 KSMEWF------TVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIA 1027
EW T I Y T+T L G EY FRV + N G E A +
Sbjct: 30075 DQHEWTKCNTTPTKIREY-----TLTHLPQGAEYRFRVLACNAGGPGEPAE-------VP 30122
Query: 1028 RDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAI 1087
K+ + Y D++ E + + G L ++G P P W K I
Sbjct: 30123 GTVKVTEMLEYPDYELDE-----RYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDI 30177
Query: 1088 VDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
R + +++ L I++ D GTY N G + K+ V
Sbjct: 30178 --SKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRV 30224
Score = 73.9 bits (180), Expect = 8e-13
Identities = 64/235 (27%), Positives = 91/235 (38%), Gaps = 46/235 (19%)
Query: 932 PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRT-SA 990
P PP V++ + E + +TW PP DG + I GY I+K K W EH +
Sbjct: 14580 PDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTY 14639
Query: 991 TITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFT 1050
T L G EY FRV +EN G+SE + T + + + D + + T
Sbjct: 14640 TAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAV------------DPIDAPKVILRT 14687
Query: 1051 QPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDD-------PRYRM-------- 1095
V G L+ S+ G+P P ITW+K++ IV + P R
Sbjct: 14688 SLEVKR----GDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEE 14743
Query: 1096 --------------FSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
S +G L +R D G Y K ND G + C + V
Sbjct: 14744 EPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSV 14798
Score = 73.9 bits (180), Expect = 8e-13
Identities = 59/203 (29%), Positives = 83/203 (40%), Gaps = 14/203 (6%)
Query: 926 IQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHY 985
++ + P PP + I D+ V+L W PK DG + ITGY I+ K S +W T I
Sbjct: 20959 VKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQW-THITTV 21017
Query: 986 HRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSE 1045
+ L G EY F+V + N G S +ES + + + + + D
Sbjct: 21018 KGLECVVRNLTEGEEYTFQVMAVNSAGRSAP----RESRPVI----VKEQTMLPELDLRG 21069
Query: 1046 APMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLE 1105
Q LV A AG N + V G PKP +TW K + R + L
Sbjct: 21070 ---IYQKLV--IAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILN 21124
Query: 1106 IRKPSPYDGGTYCCKAVNDLGTV 1128
I + D G Y A N +G V
Sbjct: 21125 INECVRSDSGPYPLTARNIVGEV 21147
Score = 73.2 bits (178), Expect = 1e-12
Identities = 52/197 (26%), Positives = 86/197 (43%), Gaps = 13/197 (6%)
Query: 930 DRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTS 989
++P PP+ + + D + L W P DG + ITGY ++ K S W H + +
Sbjct: 28544 EQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEA-GHTKQLT 28602
Query: 990 ATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMF 1049
T+ LV EY FRV ++N G SE S+VI ++ +I ++
Sbjct: 28603 FTVERLVEKTEYEFRVKAKNDAGYSEPREAF--SSVIIKEPQIEPT--------ADLTGI 28652
Query: 1050 TQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKP 1109
T L+ A G T++ + G P PK+TW ++ + + R + + + TL ++
Sbjct: 28653 TNQLITCKA--GSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDS 28710
Query: 1110 SPYDGGTYCCKAVNDLG 1126
D G Y N G
Sbjct: 28711 MRGDSGRYFLTLENTAG 28727
Score = 72.4 bits (176), Expect = 2e-12
Identities = 56/222 (25%), Positives = 101/222 (45%), Gaps = 17/222 (7%)
Query: 918 FVETASIDI--QIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKS 975
FVET+ + + I P P+ +++++V V LTW PPK DG + I Y ++ +
Sbjct: 16701 FVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGT 16760
Query: 976 MEWFTVI-EHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYK 1034
++ V ++ T+ L G+ Y +RV + N+ G + + TK I ++
Sbjct: 16761 EKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKP---ITCKDELAP 16817
Query: 1035 NPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYR 1094
++ DF T + +A+ G + G PKPK++W K++ +++D R
Sbjct: 16818 PTLHLDF----RDKLTIRVGEAFALTGRYS-------GKPKPKVSWFKDEADVLEDDRTH 16866
Query: 1095 MFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
+ + LE K D G YC N G+ + C++ V
Sbjct: 16867 IKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNV 16908
Score = 71.6 bits (174), Expect = 4e-12
Identities = 134/663 (20%), Positives = 230/663 (34%), Gaps = 120/663 (18%)
Query: 2 PEPTKKEENEVPAP----APPPEEPSKEKEAGTTPAKDWTLVETPPGEEQAKQNANSQLS 57
PEP K V +P +P P P T P TP + Q +
Sbjct: 32669 PEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKP--------TPTEKVQHLPVSAPPKI 32720
Query: 58 ILFIEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAGKHLQLKETFE 117
F++ + ++I + V +LR + W+K GK L+ F+
Sbjct: 32721 TQFLK------AEASKEIAKLTCVVESSVLRAKEVTWYKD---------GKKLKENGHFQ 32765
Query: 118 RH-SRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFK 176
H S T+E++I ++ G Y CE+
Sbjct: 32766 FHYSADGTYELKINNLTESDQGEYVCEI-------------------------------- 32793
Query: 177 RSGEGQEDAGELDFSG---------LLKRREVKQQEEEPQVDVWELLKNAKPSEYEKIAF 227
SGEG L F G + K E K+ +++ + + +P E I+
Sbjct: 32794 -SGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTEST--VTRKTEPKAPEPIS- 32849
Query: 228 QYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYK 287
K + D D + V +P+ W K
Sbjct: 32850 ---------------------SKPVIVTGLQDTTVSSDSVAKFA-VKATGEPRPTAIWTK 32887
Query: 288 NGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVT----AGDEKCSTELFVREPPIM 343
+G+ I KY L I+ +D Y T AG S +L ++ I
Sbjct: 32888 DGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKA--IK 32945
Query: 344 VTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIE 403
T+ + +T E + V +++ + K ++ E + KS+ ++ ++ + ++I
Sbjct: 32946 DTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLALKEEASKVLIS 33005
Query: 404 GATKADAA---EYSVMTTGGQSSAKLSVDLKP-LKILTPLTDQTVNLGKEICLKCEISEN 459
K AA E S++ +++ S +++ +I T ++N G+ + LK I+
Sbjct: 33006 EEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGA 33065
Query: 460 IPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV--------FAPDAYNVT 511
KW NG+ + S+ + G L I A DEG Y++T
Sbjct: 33066 TDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLT 33125
Query: 512 LPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSG 571
L ++ D P I + + G + ISGEP P+ W + + I S
Sbjct: 33126 LSKELS--DAPAFI----SQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPI-SISS 33178
Query: 572 RIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEV 631
+ + +L I A DSG Y I KN G+ A+ + V+ + P V
Sbjct: 33179 NVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRT 33238
Query: 632 GDD 634
D
Sbjct: 33239 SGD 33241
Score = 68.9 bits (167), Expect = 3e-11
Identities = 107/465 (23%), Positives = 175/465 (37%), Gaps = 76/465 (16%)
Query: 696 AVNAIGISKPSMPSR-PFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVL 754
A NA G +K + + P V P + ++T +T+ W P + G A + Y++
Sbjct: 28033 AKNASGSAKAEIKVKVQDTPGKVVGP---IRFTNITGEKMTLWWDAPLNDGCAPITHYII 28089
Query: 755 EYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVN 814
E E A+ L +D + +T L + RV AVN
Sbjct: 28090 E-----------KRETSRLAWALI--------EDKCEAQSYTAIKLINGNEYQFRVSAVN 28130
Query: 815 AAGASEPKYYSQPILVK---EIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPEL 871
G P S P++ + + + P I P ++ G ++ L RPE
Sbjct: 28131 KFGVGRP-LDSDPVVAQIQYTVPDAPGIPEPSNI-------TGNSITLTWA-----RPE- 28176
Query: 872 TWKKDGAEIDKNQINIRNSE-TDTIIFIRKAERSHS----------GKYDLQVKVDKF-- 918
G+EI + + R + T + I K S + +Y+ V +
Sbjct: 28177 --SDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAG 28234
Query: 919 VETASIDIQII------DRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKAD 972
V AS ++I + PGPP +VK+ D V+L W+ P DG I GY I+
Sbjct: 28235 VGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCK 28294
Query: 973 KKSMEWFTV-IEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGK 1031
+W V E +T T+T+L G EY FRV + N G + +T I +
Sbjct: 28295 ADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVT---GTIKAVDR 28351
Query: 1032 IYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDP 1091
+ + D +F + + AG + L + +G P P W K +
Sbjct: 28352 LTAPELDIDANFKQTHVVR---------AGASIRLFIAYQGRPTPTAVWSKPDSNL--SL 28400
Query: 1092 RYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
R + + TL + + D G Y N+ G+ I ++V
Sbjct: 28401 RADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKV 28445
Score = 64.7 bits (156), Expect = 5e-10
Identities = 75/303 (24%), Positives = 129/303 (42%), Gaps = 19/303 (6%)
Query: 341 PIMVTKQLEDT----TAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGK 396
P+ K+++D + + G EC VS A W K+G I PK +R +GK
Sbjct: 11114 PLKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPK--HRFIADGK 11171
Query: 397 KHILIIEGATKADAAEYSVMTTGGQ----SSAKLSVDLKPLKILTPLTDQ-TVNLGKEIC 451
L I +DA EY+ + G S+AKL V+ P++ + L ++ TV G+ +
Sbjct: 11172 DRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLY 11231
Query: 452 LKCEISENIPGKWTKNG-LPVQESDRLKVVHKGRIHKLVIANALTEDEGDY-VFAPDAYN 509
L CE+++ W K+G + V++ R+ G + L I +A D G Y V +A N
Sbjct: 11232 LSCELNKERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVENANN 11291
Query: 510 VTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEG 569
+ + V V++ +I D L + + + P W +G I
Sbjct: 11292 LECSSCVKVVE---VIRDWLVKPIRDQHVKPKGTAIFACDIAKDTPNIKWFKGYDEI-PA 11347
Query: 570 SGRIRTESYPDSSTLVIDI--AERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT 627
+TE D + L + I A +D Y + ++ + A ++ + V+ P T
Sbjct: 11348 EPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGKRYPAKLTLGEREVELLKPIEDVT 11407
Query: 628 VTE 630
+ E
Sbjct: 11408 IYE 11410
Score = 63.5 bits (153), Expect = 1e-09
Identities = 31/92 (33%), Positives = 43/92 (46%)
Query: 1047 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEI 1106
P L N I G + TL C + G P P +TW + I +++ G+ L I
Sbjct: 943 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMI 1002
Query: 1107 RKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1138
R+ D G + C AVN+ GTV C L V+V
Sbjct: 1003 REAFAEDSGRFTCSAVNEAGTVSTSCYLAVQV 1034
Score = 62.4 bits (150), Expect = 2e-09
Identities = 63/287 (21%), Positives = 107/287 (37%), Gaps = 18/287 (6%)
Query: 853 VGEAVNLVIPFQGKPRPELTWKKDGAEIDKN-QINIRNSETDTIIFIRKAERSHSGKYDL 911
VGE+ + G +++W KD EI + I E + + K ++ SG+Y
Sbjct: 8166 VGESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTC 8225
Query: 912 QVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKA 971
+ ++ + + I +R PP K L+ T + +GN+ + +
Sbjct: 8226 YAVNEVGKDSCTAQLNIKERLIPPSFTK---------RLSETVEETEGNSFKLEGRVAGS 8276
Query: 972 DKKSMEWF-TVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDG 1030
++ W+ IE ++ IT R N GL + +
Sbjct: 8277 QPITVAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSS 8336
Query: 1031 KIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDD 1090
+ K P + P+F Q L G L+C V+G+ +I W+K I
Sbjct: 8337 IVIKEP-------KKPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPS 8389
Query: 1091 PRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1137
R G LE+R + D G Y CKA N G+ + K+ +K
Sbjct: 8390 DRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIK 8436
Score = 61.2 bits (147), Expect = 5e-09
Identities = 33/100 (33%), Positives = 54/100 (54%), Gaps = 6/100 (6%)
Query: 931 RPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEH-YHRTS 989
RP PP++ K+ E + + W PP+ DG +ITGY ++K +K S W V +
Sbjct: 18398 RPDPPEVTKVSK---EEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERR 18454
Query: 990 ATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARD 1029
+ L+ +EY FRV +EN G+ E + ++ V+A+D
Sbjct: 18455 MKVQNLLPDHEYQFRVKAENEIGIGEPSLPSR--PVVAKD 18492
Score = 59.7 bits (143), Expect = 2e-08
Identities = 74/324 (22%), Positives = 129/324 (39%), Gaps = 19/324 (5%)
Query: 829 LVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQ--GKPRPELTWKKDGAEID----- 881
L +E P + P + + ++++ E ++V Q G P+P + WKK G +
Sbjct: 1069 LTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRY 1128
Query: 882 KNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIE 941
K N + E +I + A+ +G+Y + V+ +K ET S +++ ++K +
Sbjct: 1129 KVSYNKQTGECKLVISMTFAD--DAGEYTIVVR-NKHGET-SASASLLEEADYELLMKSQ 1184
Query: 942 DVWGENVALTWTPPKDDGNAAITGYTIQKADKK-SMEWFTVIEHYHRTSATITELVIGNE 1000
+T + G+ + +K+ E + + + + + V E
Sbjct: 1185 QEMLYQTQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDTVVVRTYVEDQE 1244
Query: 1001 YYFRVFSENMCGLSEDATM-TKESAVIARDGKIYKNPVYEDFDFSEAPM--FTQPLVNTY 1057
++ F E + E + T ++ DG+ + D SEA F + N
Sbjct: 1245 FHISSFEERLIKEIEYRIIKTTLEELLEEDGE---EKMAVDISESEAVESGFDSRIKNYR 1301
Query: 1058 AIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRM-FSNQGVCTLEIRKPSPYDGGT 1116
+ G T +C + G P PKI W K+ I RY+M F G +L I P D G
Sbjct: 1302 ILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGI 1361
Query: 1117 YCCKAVNDLGTVEIECKLEVKVIA 1140
Y A N G KL V+ A
Sbjct: 1362 YTAFASNIKGNAICSGKLYVEPAA 1385
Score = 59.3 bits (142), Expect = 2e-08
Identities = 96/426 (22%), Positives = 148/426 (34%), Gaps = 58/426 (13%)
Query: 717 VTSPPT-LLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAY 775
+ PPT + D V+ VT W PP++ G + YV+E ST+
Sbjct: 21158 IPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTT------------ 21205
Query: 776 DLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIE 835
W+ +I +T + T L T + RVKA N G P S I+
Sbjct: 21206 ------WVELATTVI-RTTYKATRLTTGLEYQFRVKAQNRYGVG-PGITSACIVANY--- 21254
Query: 836 PPKIRIPRHLKQ-TYIRRVGEAVNLVIPF------------QGKPRPELTWKKDGAEIDK 882
P K+ P Q T + + ++ P + K R + W+ +
Sbjct: 21255 PFKVPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVP 21314
Query: 883 NQINIRNSETDTIIF-IRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIE 941
I + TD I + R + +GK K K E + + ID PG P + I
Sbjct: 21315 GNIFKSSGLTDGIAYEFRVIAENMAGKS----KPSKPSEPM-LALDPIDPPGKPVPLNIT 21369
Query: 942 DVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV-IEHYHRTSATITELVIGNE 1000
V L W P+ G IT Y ++K D + W + T++ L
Sbjct: 21370 R---HTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAA 21426
Query: 1001 YYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIA 1060
Y FRV ++N G + ++ D + K V D F + + A
Sbjct: 21427 YEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKV--DVKFKDTVILK---------A 21475
Query: 1061 GYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCK 1120
G L V G P P + W K+ + + + L + + D G Y
Sbjct: 21476 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLT 21535
Query: 1121 AVNDLG 1126
A N G
Sbjct: 21536 ATNPGG 21541
Score = 57.4 bits (137), Expect = 8e-08
Identities = 95/406 (23%), Positives = 148/406 (36%), Gaps = 54/406 (13%)
Query: 694 IFAVNAIGISKPSMPSRPFVPLAVTSPPT-LLTVDSVTDTTVTMRWRPPDHIGAAGLDGY 752
I AVN +G + M L PP + +SV+ +T+ W PP G + + Y
Sbjct: 16196 ITAVNNLGTASKEMRLNV---LGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNY 16252
Query: 753 VLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKA 812
V+E + + W+ + + + T +TI L + R+ A
Sbjct: 16253 VIE------------------KREANRKTWVHVSSEPKECT-YTIPKLLEGHEYVFRIMA 16293
Query: 813 VNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIP-FQGKPRPEL 871
N G EP S+P + + P P + + R VN P + G
Sbjct: 16294 QNKYGIGEP-LDSEPETARNLFSVPGA--PDKPTVSSVTRNSMTVNWEEPEYDGGSPVTG 16350
Query: 872 TW--KKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKF----VETASID 925
W KD ++N + T+ K G D Q +V V AS+
Sbjct: 16351 YWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEGS-DYQFRVYAINAAGVGPASLP 16409
Query: 926 IQI------IDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF 979
I PGPP K+ D + L W+PP DG + +TGY ++ ++ EW
Sbjct: 16410 SDPATARDPIAPPGPP-FPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWE 16468
Query: 980 TVIEHYHR-TSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVY 1038
+ R T +T L G Y FRV + N+ G+ E +T VI ++ +
Sbjct: 16469 KGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTD---VIEMKDRLVSPDLQ 16525
Query: 1039 EDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNK 1084
D + AG + V G P P +TW N+
Sbjct: 16526 LDASVRD---------RIVVHAGGVIRIIAYVSGKPPPTVTWNMNE 16562
Score = 57.0 bits (136), Expect = 1e-07
Identities = 43/167 (25%), Positives = 72/167 (43%), Gaps = 11/167 (6%)
Query: 345 TKQLEDTTAYCGERVELECEVSEDDA-NVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIE 403
T+ L+ G E +S V WF++G+ I +I + L I
Sbjct: 9 TQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIP 68
Query: 404 GATKADAAEYSVMTTGGQSSAKLSVDL------KPLKILTPLTDQTVNLGKEICLKCEIS 457
TKA++ YS+ T G A + +L P + L TV G ++ L+ ++
Sbjct: 69 AVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVT 128
Query: 458 ENIPG---KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 501
IP K+ ++G +Q S ++ +G ++ L+IA A ED G Y
Sbjct: 129 -GIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTY 174
Score = 56.6 bits (135), Expect = 1e-07
Identities = 39/140 (27%), Positives = 56/140 (40%), Gaps = 9/140 (6%)
Query: 1003 FRVFSENMCGLSEDATM---TKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI 1059
F+ E + +SE T ES V + P+ S P+ L +T
Sbjct: 32811 FKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPI------SSKPVIVTGLQDTTVS 32864
Query: 1060 AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCC 1119
+ A G P+P W K+ AI +Y++ ++G LEI K D G Y C
Sbjct: 32865 SDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTC 32924
Query: 1120 KAVNDLGTVEIECKLEVKVI 1139
N G+V CKL +K I
Sbjct: 32925 TVKNSAGSVSSSCKLTIKAI 32944
Score = 56.6 bits (135), Expect = 1e-07
Identities = 74/348 (21%), Positives = 121/348 (34%), Gaps = 77/348 (22%)
Query: 865 GKPRPELTWKKDGAEIDKN-QINIRNSETDTIIFIRKAERSHSGKYD------------- 910
G+PRP W KDG I + + + + + I K + S SG Y
Sbjct: 32877 GEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSS 32936
Query: 911 --LQVKVDKFVETASIDIQIIDRPGPPQIVKIED------VWGENVALTWTPP------K 956
L +K K E + Q P + +++ + E + ++ K
Sbjct: 32937 CKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLALK 32996
Query: 957 DDGNAAITGYTIQKADKKSMEWFTVIEHYHRTS-------------ATITELVIGNEYYF 1003
++ + + ++K+ S+E V E +TS A T++ I NE
Sbjct: 32997 EEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSI-NEGQR 33055
Query: 1004 RVFSENMCGLSE-----------------------DATMT------KESAVIARDGKIYK 1034
V N+ G ++ D T+T ++ ++ K +
Sbjct: 33056 LVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKE 33115
Query: 1035 NPVYEDFDF------SEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIV 1088
V +D S+AP F + G N C + G P P+I W KN + I
Sbjct: 33116 GIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPIS 33175
Query: 1089 DDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
+ ++ V +LEIR S D G Y KA N G L V
Sbjct: 33176 ISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 33223
Score = 54.7 bits (130), Expect = 5e-07
Identities = 52/221 (23%), Positives = 77/221 (34%), Gaps = 45/221 (20%)
Query: 920 ETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF 979
+TA D++++ RP P E W DG + YT +
Sbjct: 1472 QTARFDLKVVGRPMP------ETFWFH-----------DGQQIVNDYTHK---------- 1504
Query: 980 TVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYE 1039
VI+ S I + + V ++N G S + + AV
Sbjct: 1505 VVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAV-------------- 1550
Query: 1040 DFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDD--PRYRMFS 1097
+ PMF + L N G + GNP P I W+KN IV P+ R+
Sbjct: 1551 --EHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEG 1608
Query: 1098 NQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1138
+G L+I D Y A+N G CK+ V+V
Sbjct: 1609 TKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEV 1649
Score = 52.4 bits (124), Expect = 2e-06
Identities = 26/95 (27%), Positives = 48/95 (50%), Gaps = 1/95 (1%)
Query: 1044 SEAPMFTQPLVNTYAI-AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVC 1102
+E P F + L + + AG ++ L C + G+P+ ++ W +N+ + +YRM V
Sbjct: 5420 TEPPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVA 5479
Query: 1103 TLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1137
+++ S D G + C+A N G+ K+ VK
Sbjct: 5480 VIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVK 5514
Score = 51.2 bits (121), Expect = 5e-06
Identities = 56/305 (18%), Positives = 122/305 (40%), Gaps = 22/305 (7%)
Query: 842 PRHLKQTYIRRVGEAVNLVIPFQ--GKPRPELTWKKDGAEID-KNQINIRNSETDTIIFI 898
P + Q + + E N++ + G+P PE+ W K+ I + ++I S + I
Sbjct: 33134 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEI 33193
Query: 899 RKAERSHSGKYDLQVKVDKFVETASIDIQIIDR-PGPPQIVKIEDVWGENVALTWTPPKD 957
R A S SGKY ++ K + +A+ + ++ P + V + ++ +++
Sbjct: 33194 RNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFSSQSV 33253
Query: 958 DGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDA 1017
+A+ + S T ++ ++ +++ + E + + S + G+S
Sbjct: 33254 QMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSM---QESFVEMSSSSFMGISNMT 33310
Query: 1018 TMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI-AGYNATLNCSVRGNPKP 1076
+ ++ + + G P + L + +I G T+ C+ G P P
Sbjct: 33311 QLESSTSKMLKAG------------IRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTP 33358
Query: 1077 KITWM--KNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKL 1134
++TW K+ + R+ + + + TL I DGG Y N+ G+ +
Sbjct: 33359 EVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNI 33418
Query: 1135 EVKVI 1139
++ I
Sbjct: 33419 HIRSI 33423
Score = 49.3 bits (116), Expect = 2e-05
Identities = 54/269 (20%), Positives = 103/269 (38%), Gaps = 30/269 (11%)
Query: 865 GKPRPELTWKKDGAEIDKNQINIRNSETDTIIF-IRKAERSHSGKYDLQVKVDKFVETAS 923
G P ++ W KDG +I ++ + E + F I+ + SG+Y +V+ D +
Sbjct: 5166 GTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCD 5225
Query: 924 IDIQIIDRPGPP----QIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSME-W 978
++++D+ PP ++ K++ V G ++ + K G+ I+ + + S
Sbjct: 5226 AYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMEC---KVSGSLPISAQWFKDGKEISTSAK 5282
Query: 979 FTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVY 1038
+ ++ H S + L + + + N+ G +DA S ++
Sbjct: 5283 YRLVCHERSVSLEVNNLELEDTANYTCKVSNVAG--DDAC----SGILT----------- 5325
Query: 1039 EDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSN 1098
E P F AI ++G P KI W K+ V +V P+ +
Sbjct: 5326 ----VKEPPSFLVKPGRQQAIPDSTVEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLE 5381
Query: 1099 QGVCTLEIRKPSPYDGGTYCCKAVNDLGT 1127
L + G Y C ND+G+
Sbjct: 5382 GSTSFLNLYSVDASKTGQYTCHVTNDVGS 5410
Score = 48.9 bits (115), Expect = 3e-05
Identities = 59/283 (20%), Positives = 97/283 (34%), Gaps = 70/283 (24%)
Query: 854 GEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQV 913
GE+V L G P P +TW ++ +I+
Sbjct: 957 GESVTLECHISGYPSPTVTWYREDYQIE-------------------------------- 984
Query: 914 KVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADK 973
+SID QI + G +++ E ++ T + + G + + Y +
Sbjct: 985 --------SSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ--- 1033
Query: 974 KSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIY 1033
V E + + + +TE E + F E+ + D ++T+E A Y
Sbjct: 1034 -------VSEEFEKETTAVTEKFTTEE---KRFVESRDVVMTDTSLTEEQAGPGEPAAPY 1083
Query: 1034 KNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRY 1093
T+P+V + G + C V GNPKP + W K+ V + RY
Sbjct: 1084 --------------FITKPVVQKL-VEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRY 1128
Query: 1094 RMFSNQ--GVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKL 1134
++ N+ G C L I D G Y N G L
Sbjct: 1129 KVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1171
Score = 48.1 bits (113), Expect = 5e-05
Identities = 51/213 (23%), Positives = 86/213 (40%), Gaps = 21/213 (9%)
Query: 932 PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSAT 991
P P+ + + + L W P+ +G + I GY I+K ++ V + T++
Sbjct: 15295 PTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSF 15354
Query: 992 ITELVIGNEYY-FRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFT 1050
+ E + ++ Y FRV + N G SE + V+ +D ++ +
Sbjct: 15355 LVENLDEHQMYEFRVKAVNEIGESEPSLPLN---VVIQDDEVPPT----------IKLRL 15401
Query: 1051 QPLVNTYAI-AGYNATLNCSVRGNPKPKITWMKNKVAI------VDDPRYRMFSNQGVCT 1103
+T + AG + V G P PKI W KN+ I + + + ++
Sbjct: 15402 SVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTE 15461
Query: 1104 LEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
L I K D GTY A N LG+V +EV
Sbjct: 15462 LSIPKAVREDKGTYTVTASNRLGSVFRNVHVEV 15494
Score = 47.4 bits (111), Expect = 8e-05
Identities = 28/96 (29%), Positives = 44/96 (45%), Gaps = 2/96 (2%)
Query: 1044 SEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDD--PRYRMFSNQGV 1101
++AP FTQPL + + G AT + G P P+++W ++ I P ++ + G
Sbjct: 3 TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGR 62
Query: 1102 CTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1137
L I + + G Y KA N G +L VK
Sbjct: 63 AKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98
Score = 46.6 bits (109), Expect = 1e-04
Identities = 36/105 (34%), Positives = 48/105 (45%), Gaps = 4/105 (3%)
Query: 512 LPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSG 571
+PA V + P ++ GL VTVI G + LE ISG P P W R D I E S
Sbjct: 932 VPAPVEIPVTPPTLVSGL---KNVTVIEGESVTLECHISGYPSPTVTWYREDYQI-ESSI 987
Query: 572 RIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKV 616
+ + L+I A +DSG + + NEAG S + V
Sbjct: 988 DFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 1032
Score = 46.6 bits (109), Expect = 1e-04
Identities = 29/93 (31%), Positives = 42/93 (45%), Gaps = 3/93 (3%)
Query: 1047 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIV---DDPRYRMFSNQGVCT 1103
P FT PL N A G N ++ +P+P +TW K+ I +D +Y S++G+
Sbjct: 31690 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQ 31749
Query: 1104 LEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
L I + D Y A N G + KL V
Sbjct: 31750 LTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 31782
Score = 45.8 bits (107), Expect = 2e-04
Identities = 29/100 (29%), Positives = 49/100 (49%), Gaps = 5/100 (5%)
Query: 932 PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEH--YHRTS 989
P P + +V ++ +TW P D G IT Y ++K + S W V + + T
Sbjct: 17012 PDAPDQPIVTEVTKDSALVTWNKPHDGGKP-ITNYILEKRETMSKRWARVTKDPIHPYTK 17070
Query: 990 ATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARD 1029
+ +L+ G +Y FRV +EN G+ + + +K V A+D
Sbjct: 17071 FRVPDLLEGCQYEFRVSAENEIGIGDPSPPSK--PVFAKD 17108
Score = 45.1 bits (105), Expect = 4e-04
Identities = 53/231 (22%), Positives = 95/231 (41%), Gaps = 17/231 (7%)
Query: 394 EGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLK 453
E + H L IE +++ E +LS +P+ ++ + +QTV + +
Sbjct: 8618 EEETHRLEIEEIERSERDEKEFEELVSFIQQRLS-QTEPVTLIKDIENQTVLKDNDAVFE 8676
Query: 454 CEISENIPG---KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNV 510
+I N P W K ++ SD+ ++ G H L + N +D+G+Y +
Sbjct: 8677 IDIKINYPEIKLSWYKGTEKLEPSDKFEISIDGDRHTLRVKNCQLKDQGNYRLVCGPHIA 8736
Query: 511 TLPAKVHVIDPP--KIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIME 568
+ AK+ VI+P + + D VT+ G + S P K+ W R + I++
Sbjct: 8737 S--AKLTVIEPAWERHLQD-------VTLKEGQTCTMTCQFS-VPNVKSEWFRNGR-ILK 8785
Query: 569 GSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDF 619
GR +TE L I +D G Y ++ A I+ + + F
Sbjct: 8786 PQGRHKTEVEHKVHKLTIADVRAEDQGQYTCKYEDLETSAELRIEAEPIQF 8836
Score = 44.7 bits (104), Expect = 5e-04
Identities = 62/284 (21%), Positives = 105/284 (36%), Gaps = 51/284 (17%)
Query: 869 PELT--WKKDGAEID-KNQINIRNSETDTIIFIRKAERSHSGKYDL----QVKVDK-FVE 920
P++T W KD E+ ++I I+ + + I S +GKY + V K FVE
Sbjct: 3084 PDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVE 3143
Query: 921 TASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNA------AITGYTIQKADKK 974
+ I+ I + +++ + + + + +DD +A + +Q+ K
Sbjct: 3144 GRDVRIRSIKK-------EVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHK- 3195
Query: 975 SMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYK 1034
+ V HR + T EY F V N ++ +Y
Sbjct: 3196 ----YVVERRIHRMFISETRQSDAGEYTF-VAGRNRSSVT-----------------LYV 3233
Query: 1035 NPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYR 1094
N E P Q L +G A + G P+PKI+W K + + + +
Sbjct: 3234 NA-------PEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCK 3286
Query: 1095 MFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1138
+ TL + + P D Y C+A ND G L V+V
Sbjct: 3287 FLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEV 3330
Score = 44.7 bits (104), Expect = 5e-04
Identities = 23/72 (31%), Positives = 32/72 (44%)
Query: 1065 TLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVND 1124
TL C V G P+ K+ W+K+ IV + M V + I+ D G Y K ND
Sbjct: 5159 TLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVEND 5218
Query: 1125 LGTVEIECKLEV 1136
G+ + L V
Sbjct: 5219 FGSSSCDAYLRV 5230
Score = 44.3 bits (103), Expect = 7e-04
Identities = 29/98 (29%), Positives = 51/98 (52%), Gaps = 1/98 (1%)
Query: 534 TVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDD 593
++TV G+++RL++ ++G P P + R D A ++ S + D +L+I A +D
Sbjct: 112 SMTVRQGSQVRLQVRVTGIPTPVVKFYR-DGAEIQSSLDFQISQEGDLYSLLIAEAYPED 170
Query: 594 SGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEV 631
SG Y +N N G A ++ ++ V + P T T V
Sbjct: 171 SGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIV 208
Score = 44.3 bits (103), Expect = 7e-04
Identities = 64/320 (20%), Positives = 110/320 (34%), Gaps = 40/320 (12%)
Query: 315 QMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEV-SEDDANVK 373
Q T + +Y E S + F + +T ++ CG+ V S+ A VK
Sbjct: 32353 QKTSERKY------EVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVK 32406
Query: 374 WFKNGEEIIPGPKSRYRIRVEGKKHILIIEGAT-------------KADAAEYSVM-TTG 419
W+ NG E+ K Y G + I++ T K +A++Y+ + TG
Sbjct: 32407 WYHNGVELQESSKIHYT-NTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTG 32465
Query: 420 GQSSAKLSV---DLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDR 476
G + S + P + LT E+ + + K+ +
Sbjct: 32466 GDYTTYASQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESL 32525
Query: 477 LKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVT 536
H + + AL E + TL A++ L ++T
Sbjct: 32526 SSYEHSASAE--MKSAALEEKSLEEKSTTRKIKTTLAARI------------LTKPRSMT 32571
Query: 537 VIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGV 596
V G R GEP P W R + ++ S R + + ST I + D G
Sbjct: 32572 VYEGESARFSCDTDGEPVPTVTWLRKGQ-VLSTSARHQVTTTKYKSTFEISSVQASDEGN 32630
Query: 597 YHINLKNEAGEAHASIKVKV 616
Y + ++N G+ A + +
Sbjct: 32631 YSVVVENSEGKQEAEFTLTI 32650
Score = 43.9 bits (102), Expect = 9e-04
Identities = 94/440 (21%), Positives = 160/440 (36%), Gaps = 71/440 (16%)
Query: 246 REEKKSAAFAKILDPAYQVDKGGRVRFVVELAD-PKLEVKWYKNGQEIRPSTKYIFEHKG 304
++EK+ +P +V +G RF + P+ +V WY NGQ IR S ++ + G
Sbjct: 1835 QKEKQKPDIVLYPEPV-RVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDG 1893
Query: 305 CQRILFINNCQMTDDSEYYVTAG------DEKCSTELFVREP------------------ 340
L I +C+ D E VTA + K E+ RE
Sbjct: 1894 I-HYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRPEFHVH 1952
Query: 341 --------------PIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGE-----EI 381
P+ T+ E ER+ E E + FK E
Sbjct: 1953 EPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEA 2012
Query: 382 IPGPKSRYRIRVEGKKHIL-------------IIEGATKADAAEYSV-MTTGGQSSAKLS 427
I + + R + E + +L + E KA A E + + T +LS
Sbjct: 2013 ITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELS 2072
Query: 428 VDLKPLKILTPLTDQTVNLGKEICLKCEI--SENIPGKWTKNGLPVQESDRLK-VVHKGR 484
++ KI + QTV G + + + + +W KNG+ ++ SDR+ +
Sbjct: 2073 PSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDN 2132
Query: 485 IHKLVIANALTEDEGDYVFAPDAYNVTLPAKVH---VIDPPKIILDGLDADNTVTVIAGN 541
+ +LVI + ED + A N+ H ++ ++I + + V
Sbjct: 2133 VCELVIRDVTAEDSASIMV--KAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDT 2190
Query: 542 KLRLEIPISGEPPPKAMWSRGDKAIMEGSG-RIRTE-SYPDSSTLVIDIAERDDSGVYHI 599
E S EP K W + + EG R+ ++ S L ID ++ +D +
Sbjct: 2191 MATFECETS-EPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLV 2249
Query: 600 NLKNEAGEAHASIKVKVVDF 619
+N A ++ VV+F
Sbjct: 2250 EDENVKTTAKLIVEGAVVEF 2269
Score = 43.9 bits (102), Expect = 9e-04
Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 1/79 (1%)
Query: 1059 IAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYC 1118
+ G A C V G P+PK+ W N I R+R+ G+ L+I YD G
Sbjct: 1853 LEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVK 1911
Query: 1119 CKAVNDLGTVEIECKLEVK 1137
A N G +E + KLE++
Sbjct: 1912 VTAENPEGVIEHKVKLEIQ 1930
Score = 43.9 bits (102), Expect = 9e-04
Identities = 59/286 (20%), Positives = 102/286 (35%), Gaps = 24/286 (8%)
Query: 854 GEAVNLVIPFQGKPRPELTWKKDGAEI-DKNQINIRNSETDTIIFIRKAERSHSGKYDLQ 912
G+ ++ Q KP E+ W +G E+ + ++I+ N+ + I SG Y +
Sbjct: 32388 GQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTY--R 32445
Query: 913 VKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKAD 972
+ AS D +D G E V + P A Y +
Sbjct: 32446 AVCTNYKGEAS-DYATLDVTGGDYTTYASQRRDEEVPRSVFPELTRTEA----YAVSSFK 32500
Query: 973 KKS-MEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGK 1031
K S ME + + + +TE E++ A+ +SA +
Sbjct: 32501 KTSEMEASSSVRE---VKSQMTET-----------RESLSSYEHSASAEMKSAALEEKSL 32546
Query: 1032 IYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDP 1091
K+ + A + T+P T G +A +C G P P +TW++ +
Sbjct: 32547 EEKSTTRKIKTTLAARILTKPRSMT-VYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSA 32605
Query: 1092 RYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1137
R+++ + + T EI D G Y N G E E L ++
Sbjct: 32606 RHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 32651
Score = 43.5 bits (101), Expect = 0.001
Identities = 61/263 (23%), Positives = 104/263 (39%), Gaps = 35/263 (13%)
Query: 261 AYQVDKGGRVRFVVEL-ADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDD 319
+++V G RF++ + + P EVKWY NG E++ S+K + + L I +C TDD
Sbjct: 32382 SHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCH-TDD 32440
Query: 320 SEYY------------------VTAGD-EKCSTELFVREPPIMVTKQLEDTTAYCGERVE 360
S Y VT GD +++ E P V +L T AY +
Sbjct: 32441 SGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPRSVFPELTRTEAYAVSSFK 32500
Query: 361 LECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGG 420
E+ E ++V+ K+ + R + +H + + +A +
Sbjct: 32501 KTSEM-EASSSVREVKS-------QMTETRESLSSYEH----SASAEMKSAALEEKSLEE 32548
Query: 421 QSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEI-SENIPG-KWTKNGLPVQESDRLK 478
+S+ + +ILT TV G+ C+ E +P W + G + S R +
Sbjct: 32549 KSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQ 32608
Query: 479 VVHKGRIHKLVIANALTEDEGDY 501
V I++ DEG+Y
Sbjct: 32609 VTTTKYKSTFEISSVQASDEGNY 32631
Score = 43.1 bits (100), Expect = 0.001
Identities = 41/170 (24%), Positives = 67/170 (39%), Gaps = 16/170 (9%)
Query: 464 WTKNGLPVQESDRLKVVHK-GRIHKLVIANALTEDEGDYVFAPD--------AYNVTLPA 514
W +G + KVV K L+I A D G++ + +T+ A
Sbjct: 1490 WFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEA 1549
Query: 515 KVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGS-GRI 573
H + P + + V + G++L +++ +G P P +W + I+ +I
Sbjct: 1550 VEHQVKPMFV-----EKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKI 1604
Query: 574 RTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKV-VDFPDP 622
R E + L ID DS Y N+AG KV V V+F +P
Sbjct: 1605 RIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEP 1654
Score = 43.1 bits (100), Expect = 0.001
Identities = 67/327 (20%), Positives = 116/327 (35%), Gaps = 65/327 (19%)
Query: 344 VTKQLEDTTAYCGERVELECEVSEDDAN--VKWFKNGEEIIPGPKSRYRIRVEGKKHILI 401
V+ Q+ G V+ C++ D + V W+ ++ K Y I E IL
Sbjct: 31570 VSGQIMHAVGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEK--YEITYEDGVAILY 31627
Query: 402 IEGATKADAAEY--SVMTTGGQSSAKLSVDLK---------------------------- 431
++ TK D Y V+ G+ S+ + +K
Sbjct: 31628 VKDITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLE 31687
Query: 432 -PLKILTPLTDQTVNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVV----HKGR 484
P + PL ++T +G+ + I+ + W K+G ++ D K KG
Sbjct: 31688 RPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKG- 31746
Query: 485 IHKLVIANALTEDEGDYV------FAPDAYNVTLPAKVHVIDPP---------KIILDGL 529
+++L I + T+D+ +Y + D+ L +H PP K +L
Sbjct: 31747 LYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLH--PPPTDSTLRPMFKRLLANA 31804
Query: 530 DADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIA 589
+ G + EI +SG PPP W + + + G D L I
Sbjct: 31805 ECQE------GQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDT 31858
Query: 590 ERDDSGVYHINLKNEAGEAHASIKVKV 616
+D+G Y + N AG ++V
Sbjct: 31859 LPEDTGYYRVTATNTAGSTSCQAHLQV 31885
Score = 42.7 bits (99), Expect = 0.002
Identities = 33/111 (29%), Positives = 46/111 (41%), Gaps = 5/111 (4%)
Query: 1021 KESAVIARDGKI----YKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKP 1076
+E +A +GKI +K E EAP + + + G +A V G P P
Sbjct: 2048 EEKKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDP 2107
Query: 1077 KITWMKNKVAIVDDPR-YRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLG 1126
+ W KN V I R Y + VC L IR + D + KA+N G
Sbjct: 2108 ECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAG 2158
Score = 42.0 bits (97), Expect = 0.003
Identities = 27/93 (29%), Positives = 41/93 (44%), Gaps = 2/93 (2%)
Query: 1047 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEI 1106
P F + G A C+V G P + W K+ A+ P +R+ + LE+
Sbjct: 3551 PTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWRISDAENKHILEL 3610
Query: 1107 RKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVI 1139
+ D G Y CKA N G +I C+ E+ +I
Sbjct: 3611 SNLTIQDRGVYSCKASNKFG-ADI-CQAELIII 3641
Score = 41.2 bits (95), Expect = 0.006
Identities = 31/101 (30%), Positives = 45/101 (44%), Gaps = 7/101 (6%)
Query: 1022 ESAVIARDGKIYKNPVYEDFDFSEAPM-FTQPLVNTYAIAGYNATLNCSVRGNPKPKITW 1080
E + A+D K + N + E P+ FT+PL + G A L C V K+ W
Sbjct: 12264 EVQLTAKDFKTHANLFVK-----EPPVEFTKPLEDQTVEEGATAVLECEV-SRENAKVKW 12317
Query: 1081 MKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKA 1121
KN I+ +Y + ++ V L I +P D TY C A
Sbjct: 12318 FKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDA 12358
Score = 40.0 bits (92), Expect = 0.013
Identities = 44/211 (20%), Positives = 95/211 (45%), Gaps = 28/211 (13%)
Query: 245 RREEKKSAAFAKILDPAYQVD-------KGGRVRFVVELAD-PKLEVKWYKNGQEIRP-- 294
R EE + ++ P + + +G RF +++ P E W+ +GQ+I
Sbjct: 1442 RLEETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDY 1501
Query: 295 STKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFV--------REPPIMVTK 346
+ K + + G Q ++ + +D E+ V A + + + V + M +
Sbjct: 1502 THKVVIKEDGTQSLIIVP-ATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVE 1560
Query: 347 QLEDTTAYCGERVELECEVSED-DANVKWFKNGEEIIPGPKSRY-RIRVEGKK--HILII 402
+L++ G R+E++ + + + ++ W KN + I+P +Y +IR+EG K L I
Sbjct: 1561 KLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVP---HKYPKIRIEGTKGEAALKI 1617
Query: 403 EGATKADAAEY--SVMTTGGQSSAKLSVDLK 431
+ D+A Y + + G+ + + V+++
Sbjct: 1618 DSTVSQDSAWYTATAINKAGRDTTRCKVNVE 1648
Score = 40.0 bits (92), Expect = 0.013
Identities = 96/465 (20%), Positives = 165/465 (35%), Gaps = 92/465 (19%)
Query: 20 EEPSKEKEAGTTPAKDWTLVETPPGEEQAKQNANSQLSILFIEKPQGGTVKVGEDITFIA 79
E S + + + K L E E+ + + L+ + KP+ TV GE F
Sbjct: 32523 ESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSC 32582
Query: 80 KVKAEDLLRKPTIKWF-KGKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAG 138
E + PT+ W KG+ + S + +H ++ TFE+ ++A D G
Sbjct: 32583 DTDGEPV---PTVTWLRKGQ---VLSTSARHQVTTTKYKS-----TFEISSVQASDE--G 32629
Query: 139 NYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRRE 198
NY V + F L + ++ T + K S E + + E + +
Sbjct: 32630 NYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVK-SPEPRVKSPE----AVKSPKR 32684
Query: 199 VKQQEEEPQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKIL 258
VK E V KP+ EK+ + K + ++ E K A
Sbjct: 32685 VKSPEPSHPKAVSP--TETKPTPTEKVQH----LPVSAPPKITQFLKAEASKEIA----- 32733
Query: 259 DPAYQVDKGGRVRFVVELADPKL-EVKWYKNGQEIRPSTKYIFEHKGCQRI-LFINNCQM 316
++ VVE + + EV WYK+G++++ + + F + L INN
Sbjct: 32734 ----------KLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTE 32783
Query: 317 TDDSEYY---------------------------------VTAGDEKCSTELFVR--EP- 340
+D EY D+K + R EP
Sbjct: 32784 SDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPK 32843
Query: 341 --------PIMVTKQLEDTTAYCGERVELECEVS-EDDANVKWFKNGEEIIPGPKSRYRI 391
P++VT L+DTT + + + E W K+G+ I G K Y++
Sbjct: 32844 APEPISSKPVIVT-GLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGK--YKL 32900
Query: 392 RVEGKKHILIIEGATKADAAEY--SVMTTGGQSSAKLSVDLKPLK 434
+ L I +D+ Y +V + G S+ + +K +K
Sbjct: 32901 SEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIK 32945
Score = 39.7 bits (91), Expect = 0.017
Identities = 25/98 (25%), Positives = 37/98 (37%)
Query: 1039 EDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSN 1098
+ F AP T + + G N +V+ P ++ W N V + + + +
Sbjct: 32366 QPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNT 32425
Query: 1099 QGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
GV TLEI D GTY N G L+V
Sbjct: 32426 SGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDV 32463
Score = 39.3 bits (90), Expect = 0.022
Identities = 58/327 (17%), Positives = 107/327 (32%), Gaps = 45/327 (13%)
Query: 854 GEAVNLVIPFQGKPRPELTWKKDGAEIDKN---QINIRNSETDTIIFIRKAERSHSGKYD 910
G+ + G+P PE W DG +I + ++ I+ T ++I + A S SG++
Sbjct: 1471 GQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIV-PATPSDSGEWT 1529
Query: 911 L--QVKVDKFVETASIDIQIIDRPGPPQIV----------------KIEDVWGENVALTW 952
+ Q + + + + ++ ++ P V K+ N + W
Sbjct: 1530 VVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVW 1589
Query: 953 TPPKD------------DGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNE 1000
D +G I + W+T ++ T + E
Sbjct: 1590 LKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATA-INKAGRDTTRCKVNVE 1648
Query: 1001 YYFR--------VFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQP 1052
F + E A E + + ++ D + + P F +
Sbjct: 1649 VEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKK 1708
Query: 1053 LVNTYAIAGYNATLNCSVR--GNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPS 1110
L + A C + G+P + W+ + + R RM + G C+L+
Sbjct: 1709 LTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAY 1768
Query: 1111 PYDGGTYCCKAVNDLGTVEIECKLEVK 1137
D G C+A N GT L VK
Sbjct: 1769 SRDSGIITCRATNKYGTDHTSATLIVK 1795
Score = 38.9 bits (89), Expect = 0.028
Identities = 44/162 (27%), Positives = 69/162 (42%), Gaps = 13/162 (8%)
Query: 279 PKLEVKWYKNGQEIRPST--KYIFEHKGCQRILFINNCQMTDDSEYYVTA----GDEKCS 332
P EV W+++GQ I ST + L I + Y + A G +
Sbjct: 33 PVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKATNGSGQATST 92
Query: 333 TELFVR---EPPIMVTKQLEDTTAYCGERVELECEVSE-DDANVKWFKNGEEIIPGPKSR 388
EL V+ PP V ++L+ T G +V L+ V+ VK++++G EI
Sbjct: 93 AELLVKAETAPPNFV-QRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEI--QSSLD 149
Query: 389 YRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDL 430
++I EG + L+I A D+ YSV T A + +L
Sbjct: 150 FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAEL 191
Score = 38.5 bits (88), Expect = 0.037
Identities = 75/342 (21%), Positives = 130/342 (38%), Gaps = 50/342 (14%)
Query: 316 MTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDA-NVKW 374
MTD S AG + + F+ +P +V K +E G V C+V + +V W
Sbjct: 1064 MTDTSLTEEQAGPGEPAAPYFITKP--VVQKLVE------GGSVVFGCQVGGNPKPHVYW 1115
Query: 375 FKNGEEIIPGPKSRYRIRVEGKKHI----LIIEGATKADAAEYSVMTTG--GQSSAKLSV 428
K+G + G YR +V K L+I DA EY+++ G++SA S+
Sbjct: 1116 KKSGVPLTTG----YRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1171
Query: 429 DLKPLKILTPLTDQTVNLGKEICL---KCEISENIPGKWTKNGLPVQESDRLKVVHKGRI 485
+ L + Q + ++ + ++ E PG + + + ++ K
Sbjct: 1172 LEEADYELLMKSQQEMLYQTQVTAFVQEPKVGETAPG-FVYSEYEKEYEKEQALIRKKMA 1230
Query: 486 HKLVIANALTEDEGDYVFAPDA----------YNVTLPAKVHVIDPPKIILD-------- 527
V+ ED+ ++ + + TL + K+ +D
Sbjct: 1231 KDTVVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVE 1290
Query: 528 -GLDAD-NTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS-STL 584
G D+ ++ G + +SG P PK W + K I G R + + D ++L
Sbjct: 1291 SGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGE-RYQMDFLQDGRASL 1349
Query: 585 VIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAP 626
I + +D G+Y N G A S K+ V P AP
Sbjct: 1350 RIPVVLPEDEGIYTAFASNIKGNAICSGKLYV-----EPAAP 1386
Score = 38.1 bits (87), Expect = 0.048
Identities = 27/98 (27%), Positives = 41/98 (41%), Gaps = 3/98 (3%)
Query: 1042 DFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGV 1101
D + PMF + L N G + V G P P + W K+ + P + ++G+
Sbjct: 31790 DSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEII-HEGL 31848
Query: 1102 --CTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1137
L IR P D G Y A N G+ + L+V+
Sbjct: 31849 DYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 31886
Score = 37.7 bits (86), Expect = 0.063
Identities = 26/83 (31%), Positives = 34/83 (40%), Gaps = 5/83 (6%)
Query: 264 VDKGGRVRFVVELAD-PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 322
V G VRF + P KW +G EI+ Y E +L I NC D EY
Sbjct: 17522 VKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEY 17581
Query: 323 YVT----AGDEKCSTELFVREPP 341
+T AG + + L V + P
Sbjct: 17582 QITVSNAAGSKTVAVHLTVLDVP 17604
Score = 37.7 bits (86), Expect = 0.063
Identities = 19/65 (29%), Positives = 31/65 (47%)
Query: 1077 KITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
++TW + + +Y + GV L ++ + D GTY CK VND G +L V
Sbjct: 31599 QVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFV 31658
Query: 1137 KVIAQ 1141
K + +
Sbjct: 31659 KGVRE 31663
Score = 37.0 bits (84), Expect = 0.11
Identities = 25/94 (26%), Positives = 40/94 (42%), Gaps = 1/94 (1%)
Query: 1047 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYR-MFSNQGVCTLE 1105
P+F V+ + G A + V G P P+ W + IV+D ++ + G +L
Sbjct: 1457 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLI 1516
Query: 1106 IRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVI 1139
I +P D G + A N G I L V+ +
Sbjct: 1517 IVPATPSDSGEWTVVAQNRAGRSSISVILTVEAV 1550
Score = 36.6 bits (83), Expect = 0.14
Identities = 53/275 (19%), Positives = 95/275 (34%), Gaps = 51/275 (18%)
Query: 340 PPIMVTKQLEDTTAYCGERVELECEVSE-DDANVKWFKNGEEIIPGPKSRYRIRVEGKKH 398
PP +V+ L++ T GE V LEC +S V W++ +I ++I +
Sbjct: 942 PPTLVSG-LKNVTVIEGESVTLECHISGYPSPTVTWYREDYQI--ESSIDFQITFQSGIA 998
Query: 399 ILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISE 458
L+I A D+ + T VN + C ++
Sbjct: 999 RLMIREAFAEDSGRF--------------------------TCSAVNEAGTVSTSCYLAV 1032
Query: 459 NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIAN-ALTEDEGDYVFAPDAYNVTLPAKVH 517
+ ++ K V E + +V+ + +LTE++ Y +T P
Sbjct: 1033 QVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQK 1092
Query: 518 VIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSG-RIRTE 576
+++ G + + G P P W + + G ++
Sbjct: 1093 LVE-------------------GGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYN 1133
Query: 577 SYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHAS 611
LVI + DD+G Y I ++N+ GE AS
Sbjct: 1134 KQTGECKLVISMTFADDAGEYTIVVRNKHGETSAS 1168
Score = 36.2 bits (82), Expect = 0.18
Identities = 45/250 (18%), Positives = 92/250 (36%), Gaps = 31/250 (12%)
Query: 873 WKKDGAEIDKN-QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDR 931
W KDG EI + + +I+ I+ I+KA+ G+Y DK +++ ++I
Sbjct: 11694 WFKDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKV 11753
Query: 932 PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSAT 991
P V++ + + + P G + G + T++
Sbjct: 11754 EKPLYGVEVFVGETAHFEIELSEPDVHGQWKLKGQPL-------------------TASP 11794
Query: 992 ITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQ 1051
E++ + + + G++ + + +A A + K+ + P+ +F
Sbjct: 11795 DCEIIEDGKKHILILHNCQLGMTGEVSFQAANAKSAANLKVKELPL----------IFIT 11844
Query: 1052 PLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSP 1111
PL + A C V PK W+K I D R+ + + ++ I+ +
Sbjct: 11845 PLSDVKVFEKDEAKFECEVSREPK-TFRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAF 11903
Query: 1112 YDGGTYCCKA 1121
D Y +A
Sbjct: 11904 EDEAKYMFEA 11913
Score = 36.2 bits (82), Expect = 0.18
Identities = 39/146 (26%), Positives = 56/146 (38%), Gaps = 11/146 (7%)
Query: 276 LADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTEL 335
L PK V W K Q ++ + + FE IL IN C +D Y +TA +
Sbjct: 21090 LGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARN------- 21142
Query: 336 FVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEG 395
V E ++T Q+ D ++ + EVS D W E P S Y + +
Sbjct: 21143 IVGEVGDVITIQVHDIPGPPTGPIKFD-EVSSDFVTFSW-DPPENDGGVPISNYVVEMRQ 21200
Query: 396 KKHILIIEGATKADAAEYSV--MTTG 419
+E AT Y +TTG
Sbjct: 21201 TDSTTWVELATTVIRTTYKATRLTTG 21226
Score = 35.8 bits (81), Expect = 0.24
Identities = 25/91 (27%), Positives = 42/91 (46%), Gaps = 1/91 (1%)
Query: 534 TVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS-STLVIDIAERD 592
+V V+ G+ E ISG P P+ W R + I + S+ D + L I +
Sbjct: 14 SVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKA 73
Query: 593 DSGVYHINLKNEAGEAHASIKVKVVDFPDPP 623
+SG Y + N +G+A ++ ++ V PP
Sbjct: 74 NSGRYSLKATNGSGQATSTAELLVKAETAPP 104
Score = 35.8 bits (81), Expect = 0.24
Identities = 23/89 (25%), Positives = 34/89 (38%), Gaps = 2/89 (2%)
Query: 536 TVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSG--RIRTESYPDSSTLVIDIAERDD 593
T G +R + I+ P P W + + I G + ES L I+ DD
Sbjct: 31700 TAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDD 31759
Query: 594 SGVYHINLKNEAGEAHASIKVKVVDFPDP 622
Y + +N+ GE K+ V P P
Sbjct: 31760 DAEYTVVARNKYGEDSCKAKLTVTLHPPP 31788
Score = 35.0 bits (79), Expect = 0.41
Identities = 23/91 (25%), Positives = 37/91 (40%)
Query: 1047 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEI 1106
P F Q L + G L V G P P + + ++ I +++ + +L I
Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLI 163
Query: 1107 RKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1137
+ P D GTY A N +G +L V+
Sbjct: 164 AEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 35.0 bits (79), Expect = 0.41
Identities = 27/90 (30%), Positives = 39/90 (43%), Gaps = 4/90 (4%)
Query: 1047 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEI 1106
P FT L + A+ TL C V + K W K+ IV P+Y + ++ L+I
Sbjct: 11663 PYFTVKLHDKTAVEKDEITLKCEVSKDVPVK--WFKDGEEIVPSPKYSIKADGLRRILKI 11720
Query: 1107 RKPSPYDGGTYCCKAVND--LGTVEIECKL 1134
+K D G Y C D V +E +L
Sbjct: 11721 KKADLKDKGEYVCDCGTDKTKANVTVEARL 11750
Score = 33.9 bits (76), Expect = 0.91
Identities = 27/119 (22%), Positives = 51/119 (42%), Gaps = 11/119 (9%)
Query: 393 VEGKKHILIIEGATKADAAEYSVM-------TTGGQSSAKLSVDLKPLKILTPLTDQTVN 445
VE KK + + T + V+ T + A + + + P +++ L + TV
Sbjct: 896 VEVKKEVGVSITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVI 955
Query: 446 LGKEICLKCEISENIPGK---WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 501
G+ + L+C IS P W + ++ S ++ + I +L+I A ED G +
Sbjct: 956 EGESVTLECHIS-GYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRF 1013
Score = 33.5 bits (75), Expect = 1.2
Identities = 35/140 (25%), Positives = 63/140 (45%), Gaps = 11/140 (7%)
Query: 792 KTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIR 851
+ K TI + +KA N +G + + +LVK PP + L+ +R
Sbjct: 62 RAKLTIPAVTKANSGRYSLKATNGSGQATS---TAELLVKAETAPPNF--VQRLQSMTVR 116
Query: 852 RVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTI--IFIRKAERSHSGKY 909
+ G V L + G P P + + +DGAEI ++ ++ + S+ + + I +A SG Y
Sbjct: 117 Q-GSQVRLQVRVTGIPTPVVKFYRDGAEI-QSSLDFQISQEGDLYSLLIAEAYPEDSGTY 174
Query: 910 DLQV--KVDKFVETASIDIQ 927
+ V + TA + +Q
Sbjct: 175 SVNATNSVGRATSTAELLVQ 194
Score = 33.5 bits (75), Expect = 1.2
Identities = 105/543 (19%), Positives = 203/543 (37%), Gaps = 71/543 (13%)
Query: 3 EPTKKEENEVP-APAPPPEEPSKEKEAGTTPAKDWTLVETPPGEEQAKQNANSQLSILFI 61
+P K EE P P PPE PS E +L + P K + S+++ +I
Sbjct: 30312 KPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRP-----KDDGGSRVTGYYI 30366
Query: 62 EKPQGGTVK-VGEDITFIAKVKAEDLLRKPTIKWF------KGKWMDLASKAGKHLQLKE 114
E+ + T K V + T I P ++ + S A + + K+
Sbjct: 30367 ERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKD 30426
Query: 115 TFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSA 174
F++ S+ E+ I DS + E E G +
Sbjct: 30427 PFDKPSQPGELEILSISK------------------DSVTLQWEKPECDGGKEILGYWVE 30468
Query: 175 FKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLKNAKPSEYEKIAF---QYGI 231
+++SG+ ++ K++ ++ Q + LL+ +EYE F + G+
Sbjct: 30469 YRQSGDSAW------------KKSNKERIKDKQFTIGGLLE---ATEYEFRVFAENETGL 30513
Query: 232 TDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQE 291
+ R +K + ++ D ++ + ++ + + P ++KWY+ G+E
Sbjct: 30514 SRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQI-VGRPLPDIKWYRFGKE 30572
Query: 292 IRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTA----GDEKCSTELFVREPPIMVT-- 345
+ S KY G L + + D+ Y A G+ + S++L ++ P
Sbjct: 30573 LIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGY 30632
Query: 346 KQLEDTTAYCGERVELE-CEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEG 404
E G + L + + WF +G++++ ++ E H+++
Sbjct: 30633 PLKEKYYGAVGSTLRLHVMYIGRPVPAMTWF-HGQKLLQNSENITIENTEHYTHLVMKNV 30691
Query: 405 ATKADAAEYSVMTTG--GQSSAKLSVDL--KPLKILTPLTDQTVNLGKEICLKCEISENI 460
K A +Y V + G A L V++ KP K P+ + + L + + +
Sbjct: 30692 QRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEAL-LKNSAVISWKPPADD 30750
Query: 461 PGKWTKNGL----PVQESDRLKVVHKG-RIHKLVIANALTEDEGDY--VFAPDAYNVTLP 513
G W N + +E ++V + I N LTE+ G Y V A + + ++ P
Sbjct: 30751 GGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVN-LTENAGYYFRVSAQNTFGISDP 30809
Query: 514 AKV 516
+V
Sbjct: 30810 LEV 30812
Score = 33.5 bits (75), Expect = 1.2
Identities = 43/147 (29%), Positives = 59/147 (40%), Gaps = 10/147 (6%)
Query: 279 PKLEVKWYKNGQE-IRPSTKY-IFEHKGCQRILFINNCQMTDDSEYYVTA----GDEKCS 332
PK VKWY+ G+E I KY I E KG L I + D + Y V A G +
Sbjct: 30955 PKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGT 31014
Query: 333 TELFVREP-PIMVTKQLED---TTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSR 388
L V P I + K LE A GE V ++ S V ++ G+++I
Sbjct: 31015 ASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHY 31074
Query: 389 YRIRVEGKKHILIIEGATKADAAEYSV 415
I ++ G + DA Y V
Sbjct: 31075 QVIVTRSFTSLVFPNGVERKDAGFYVV 31101
Score = 33.1 bits (74), Expect = 1.5
Identities = 21/96 (21%), Positives = 41/96 (42%), Gaps = 3/96 (3%)
Query: 847 QTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ---INIRNSETDTIIFIRKAER 903
Q+ + G G P PE++W +DG I + + I S+ + I +
Sbjct: 13 QSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTK 72
Query: 904 SHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVK 939
++SG+Y L+ T++ ++ + PP V+
Sbjct: 73 ANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQ 108
Score = 33.1 bits (74), Expect = 1.5
Identities = 21/93 (22%), Positives = 39/93 (41%), Gaps = 1/93 (1%)
Query: 538 IAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVY 597
+ G R ++ + G P P+ W + I+ + +L+I A DSG +
Sbjct: 1469 LEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEW 1528
Query: 598 HINLKNEAGEAHASIKVKVVDFPDPPVAPTVTE 630
+ +N AG + S+ + V+ + V P E
Sbjct: 1529 TVVAQNRAGRSSISV-ILTVEAVEHQVKPMFVE 1560
Score = 33.1 bits (74), Expect = 1.5
Identities = 19/61 (31%), Positives = 27/61 (44%), Gaps = 1/61 (1%)
Query: 1064 ATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVN 1123
AT C P K+ W K+ + + + +YRM S++ V L I D Y C V
Sbjct: 2192 ATFECET-SEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVE 2250
Query: 1124 D 1124
D
Sbjct: 2251 D 2251
Score = 32.3 bits (72), Expect = 2.6
Identities = 31/118 (26%), Positives = 46/118 (38%), Gaps = 20/118 (16%)
Query: 1038 YEDFDFS-------EAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDD 1090
YED + S E FT+ + N +AT C V + +TW K + +
Sbjct: 8818 YEDLETSAELRIEAEPIQFTKRIQNIVVSEHQSATFECEVSFDDAI-VTWYKGPTELTES 8876
Query: 1091 PRYRMFSNQGVC-TLEIRKPSPYDGGTYC----------CKAVNDLGTVEIECKLEVK 1137
+Y F N G C + I +P D G Y ++ +L E KLE+K
Sbjct: 8877 QKYN-FRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRGEARSTAELYLTTKEIKLELK 8933
Score = 32.3 bits (72), Expect = 2.6
Identities = 27/117 (23%), Positives = 42/117 (35%), Gaps = 9/117 (7%)
Query: 1004 RVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYN 1063
R+ N C L ++A + E G + E +FT+ L N
Sbjct: 12428 RILVINKCLLDDEAEYSCEVRTARTSGMLTV--------LEEEAVFTKNLANIEVSETDT 12479
Query: 1064 ATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCK 1120
L C V P ++ W K I++ RY + + L I+ D G Y C+
Sbjct: 12480 IKLVCEV-SKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNCR 12535
Score = 32.3 bits (72), Expect = 2.6
Identities = 16/45 (35%), Positives = 22/45 (48%), Gaps = 3/45 (6%)
Query: 836 PPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI 880
PP+ +P + K Y VGE V + P P +TW K G +I
Sbjct: 31689 PPEFTLPLYNKTAY---VGENVRFGVTITVHPEPHVTWYKSGQKI 31730
Score = 31.6 bits (70), Expect = 4.5
Identities = 26/88 (29%), Positives = 33/88 (37%), Gaps = 4/88 (4%)
Query: 1052 PLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSP 1111
PL + I G A L C V + W N I D R + L I +
Sbjct: 2450 PLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHA 2509
Query: 1112 YDGGTYCCKAVNDLGTVEIECKLEVKVI 1139
D G Y K + +G VE C L V+ I
Sbjct: 2510 SDEGPY--KLI--VGRVETNCNLSVEKI 2533
Score = 31.2 bits (69), Expect = 5.9
Identities = 15/66 (22%), Positives = 30/66 (45%), Gaps = 1/66 (1%)
Query: 262 YQVDKGGRVRFVVE-LADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDS 320
Y + G ++ + + P+ + W K+G+ ++ +T+ E +L I D
Sbjct: 24321 YSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFG 24380
Query: 321 EYYVTA 326
+Y VTA
Sbjct: 24381 KYTVTA 24386
>gi|110349717 titin isoform novex-2 [Homo sapiens]
Length = 27118
Score = 288 bits (738), Expect = 2e-77
Identities = 218/774 (28%), Positives = 346/774 (44%), Gaps = 70/774 (9%)
Query: 272 FVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKC 331
F +L+ K VKWY+NG+EI+ KY FE G L I +C++ D+ EY D K
Sbjct: 6537 FSCQLSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYACGVEDRKS 6596
Query: 332 STELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRI 391
LFV E P+ + + +D G V E+++D V+W +N ++ G K +++
Sbjct: 6597 RARLFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQWLRNNMVVVQGDK--HQM 6654
Query: 392 RVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEIC 451
EGK H L I D EY + ++ AKL + P KI T D V++GK +
Sbjct: 6655 MSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLELAAAP-KIKTADQDLVVDVGKPLT 6713
Query: 452 LKC--EISENIPGKWTKNGLPV----------QESDRL---KVVHKGRIHKLVIANALTE 496
+ + +W K P+ Q S R+ K KGR +K+V+ N +
Sbjct: 6714 MVVPYDAYPKAEAEWFKENEPLSTKTIDTTAEQTSFRILEAKKGDKGR-YKIVLQNKHGK 6772
Query: 497 DEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPK 556
EG + VID P + + + T T L E P++
Sbjct: 6773 AEGFI-------------NLKVIDVPGPVRN---LEVTETFDGEVSLAWEEPLTDGGSKI 6816
Query: 557 AMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG-----EAHAS 611
+ + I + + T+ V + + ++ ++ +N G E
Sbjct: 6817 IGYVVERRDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNP 6876
Query: 612 IKVKV-VDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLN 670
++ + D P PP+ T+T+V + WEPP YDGG+ I Y IE + K S RW
Sbjct: 6877 VEARSKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAM 6936
Query: 671 FDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV----PLAVTSPPTLLTV 726
++ + ++EG Y R+ A N IG+ KPS + PFV P+ SPP LT
Sbjct: 6937 TVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAAT-PFVKVADPIERPSPPVNLTS 6995
Query: 727 DSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVAN 786
T ++V ++W PP G + + GY++E C EG ++WI N
Sbjct: 6996 SDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGK------------------DNWIRCN 7037
Query: 787 KDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLK 846
L+ + + +TGL K RV A N AG S+P P+ + P + + K
Sbjct: 7038 MKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSA-FK 7096
Query: 847 QTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDK-NQINIRNSETDTIIFIRKAERSH 905
V + +++P G PRP TW ++ +++ ++ + I +ERS
Sbjct: 7097 DGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSD 7156
Query: 906 SGKYDLQVKVDKFVETAS--IDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAI 963
G Y L K++ V+T S ID+ +I RP P+ +K D+ ++V LTW PP DDG + +
Sbjct: 7157 KGIYTL--KLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPL 7214
Query: 964 TGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDA 1017
TGY ++K + W V++ T+ +LV G EY F+V + N CG E A
Sbjct: 7215 TGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 7268
Score = 278 bits (711), Expect = 2e-74
Identities = 166/521 (31%), Positives = 269/521 (51%), Gaps = 35/521 (6%)
Query: 511 TLPAKVHV---IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIM 567
TLP V I+PP+I LD D V + A LRL + I G P P+ W + + +
Sbjct: 18786 TLPGSVVAQERIEPPEIELDA-DLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILT 18844
Query: 568 EGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT 627
+ R + E + LVID R DSG Y++ L+N +G A + V+V+D P PV T
Sbjct: 18845 D---RAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLT 18901
Query: 628 VTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEG 687
+ EV D ++WEPP DGG+ I Y +E+++ + + + C +TTF + + EG
Sbjct: 18902 IREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNN-CTKTTFRIENLQEG 18960
Query: 688 VAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAA 747
+Y R+ A N GI P+ + P PP +T+ VT T T++W P+ G +
Sbjct: 18961 CSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGS 19020
Query: 748 GLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIF 807
+ GYV+E +GS E W + + + TI+GL +
Sbjct: 19021 KITGYVVEMQTKGS------------------EKWSTCTQ--VKTLEATISGLTAGEEYV 19060
Query: 808 VRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKP 867
RV AVN G S+P+ P++ ++I P + +P H T+ + E + + +PF+G+P
Sbjct: 19061 FRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFH---TFNVKAREQLKIDVPFKGRP 19117
Query: 868 RPELTWKKDGAEI-DKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDI 926
+ + W+KDG + + ++N+ +S+T T + I++A + G Y+L V T I I
Sbjct: 19118 QATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITI 19177
Query: 927 QIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYH 986
++DRPGPP ++I++V +++ ++W PP+ DG I+ Y ++K + S W V +
Sbjct: 19178 IVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVA 19237
Query: 987 RTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIA 1027
RTS I L G+EY FRV +EN G S + ++ SAV+A
Sbjct: 19238 RTSIKIVRLTTGSEYQFRVCAENRYGKS---SYSESSAVVA 19275
Score = 270 bits (691), Expect = 4e-72
Identities = 179/588 (30%), Positives = 288/588 (48%), Gaps = 53/588 (9%)
Query: 438 PLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQ------ESDRLKVVHKGRIHKLVIA 491
P+ D + I KC++S G+WT P E ++L H+ I
Sbjct: 16556 PIYDGGCEIQGYIVEKCDVSV---GEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAIN 16612
Query: 492 NALTEDEGDYVFAPDAYNVTLPAKVHV---IDPPKIILDGLDADNTVTVIAGNKLRLEIP 548
A + D +P + V ++ P I LD L+ + + AG LRL +P
Sbjct: 16613 KAGVGEHAD-----------VPGPIIVEEKLEAPDIDLD-LELRKIINIRAGGSLRLFVP 16660
Query: 549 ISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEA 608
I G P P+ W + D I + + T S+ ++LV+D R DSG Y + L+N +G
Sbjct: 16661 IKGRPTPEVKWGKVDGEIRDAAIIDVTSSF---TSLVLDNVNRYDSGKYTLTLENSSGTK 16717
Query: 609 HASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMR 668
A + V+V+D P PPV VTE+ D + WEPP DGGS I Y +E+++ +
Sbjct: 16718 SAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAA 16777
Query: 669 LNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDS 728
+ + C + +++ ++ EG +Y R+ A N GI P+ + P V PP +TVD
Sbjct: 16778 VVTN-CHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDD 16836
Query: 729 VTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKD 788
VT +V++ W P+H G + + Y++E AK S++ E A
Sbjct: 16837 VTRNSVSLSWTKPEHDGGSKIIQYIVE------MQAKHSEKWSECA-------------- 16876
Query: 789 LIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQT 848
+ + IT L + RV AVN G S+P+ + PI+ K+++ P + + +
Sbjct: 16877 RVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDV---KPAFSS 16933
Query: 849 YIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDK-NQINIRNSETDTIIFIRKAERSHSG 907
Y +VG+ + + +P G+P+P +TW KDG + + +IN+ +S T + I++ + G
Sbjct: 16934 YSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGG 16993
Query: 908 KYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWGENVALTWTPPKDDGNAAITGY 966
+Y + V +TASI+I +D+P PP+ VK +DV E++ L+W PP G IT Y
Sbjct: 16994 QYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNY 17053
Query: 967 TIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLS 1014
+QK D + W V RT+ +T+L G EY FR+F+EN G S
Sbjct: 17054 IVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQS 17101
Score = 259 bits (662), Expect = 1e-68
Identities = 158/580 (27%), Positives = 280/580 (48%), Gaps = 37/580 (6%)
Query: 519 IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESY 578
++ P++ LD + + V AG R+ IP G P P+ WSR + E + +++ E
Sbjct: 17714 LEAPELDLDS-ELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEG---EFTDKVQIEKG 17769
Query: 579 PDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIM 638
+ + L ID +R+D+G Y + L+N +G A + VKV+D P PP V EV D +
Sbjct: 17770 VNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFL 17829
Query: 639 NWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVN 698
WEPP DGG+ + Y I++++ + ++ C +T+F+ + + EG Y R+ A N
Sbjct: 17830 VWEPPIIDGGAKVKNYVIDKRESTRKAYANVS-SKCSKTSFKVENLTEGAIYYFRVMAEN 17888
Query: 699 AIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCF 758
G+ P SPP +T+ V+ T+ ++ W P+H G + + GYV+E
Sbjct: 17889 EFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQP 17948
Query: 759 EGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGA 818
+G+ E W + + + +TGL + + RVKA N G
Sbjct: 17949 KGT------------------EKWSIVAESKV--CNAVVTGLSSGQEYQFRVKAYNEKGK 17988
Query: 819 SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGA 878
S+P+ P++ K++ P +++P + TY + GE + + IP G+PRP ++W KDG
Sbjct: 17989 SDPRVLGVPVIAKDLTIQPSLKLPFN---TYSIQAGEDLKIEIPVIGRPRPNISWVKDGE 18045
Query: 879 EIDK-NQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPP-Q 936
+ + ++N+ + T T++ I++ + GKY + T ++ + ++++PGPP
Sbjct: 18046 PLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVG 18105
Query: 937 IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELV 996
V+ ++V + V ++W PP G I+ Y ++K D + W V RT+ IT+L
Sbjct: 18106 PVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTIKITKLK 18165
Query: 997 IGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNT 1056
G EY FR+F+EN G S A + ++ ++ +K P F + Q LV
Sbjct: 18166 TGTEYQFRIFAENRYGKS--APLDSKAVIVQYP---FKEPGPPGTPFVTSISKDQMLVQW 18220
Query: 1057 YAIAGYNAT--LNCSVRGNPKPKITWMKNKVAIVDDPRYR 1094
+ T + + K I W+K + D +++
Sbjct: 18221 HEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFK 18260
Score = 248 bits (632), Expect = 3e-65
Identities = 149/496 (30%), Positives = 252/496 (50%), Gaps = 30/496 (6%)
Query: 521 PPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPD 580
PP+I LD D VT+ A LRL +PI G P P+ W+R ++ + T SY
Sbjct: 15552 PPEIELDA-DLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESLDKASIESTSSY-- 15608
Query: 581 SSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNW 640
+ L++ R DSG Y + ++N +G A + V+V+D P PP V EV + W
Sbjct: 15609 -TLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTW 15667
Query: 641 EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAI 700
+PP DGGS I Y +E+++ + + + C +T+++ ++ EG +Y R+ A N
Sbjct: 15668 DPPLLDGGSKIKNYIVEKRESTRKAYSTVATN-CHKTSWKVDQLQEGCSYYFRVLAENEY 15726
Query: 701 GISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEG 760
GI P+ + PP +T+ VT +V++ W P+H G + + GY++E +G
Sbjct: 15727 GIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKG 15786
Query: 761 STSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASE 820
S + W A + T+ TITGL + RV A N G S+
Sbjct: 15787 S------------------DKW--ATCATVKVTEATITGLIQGEEYSFRVSAQNEKGISD 15826
Query: 821 PKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI 880
P+ S P++ K+++ PP ++ L T+ GE + + +PF G+P P +TW KD +
Sbjct: 15827 PRQLSVPVIAKDLVIPPAFKL---LFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPL 15883
Query: 881 DK-NQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IV 938
+ ++N ++E ++++ I+ A R G Y +++ ++++ ++D+PGPP V
Sbjct: 15884 KQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPV 15943
Query: 939 KIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIG 998
K+++V +++ L+W PPK DG ++I Y ++K D + W V RT+ L G
Sbjct: 15944 KMDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVSATVARTTIKACRLKTG 16003
Query: 999 NEYYFRVFSENMCGLS 1014
EY FR+ +EN G S
Sbjct: 16004 CEYQFRIAAENRYGKS 16019
Score = 244 bits (624), Expect = 3e-64
Identities = 156/511 (30%), Positives = 243/511 (47%), Gaps = 35/511 (6%)
Query: 518 VIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRG--DKAIMEGSGRIRT 575
+++PP+I LD V V AG +RL + G P PK W + D + +G +
Sbjct: 12295 ILEPPEIDLDA-SMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKG----QV 12349
Query: 576 ESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDW 635
+ + LVI + RDDSG Y + L N AGE + V+V+D P P V++V
Sbjct: 12350 DLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTS 12409
Query: 636 CIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIF 695
C ++W PP DGGS + Y +E+++ W + ++ K+T+F ++ G Y R+
Sbjct: 12410 CHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEV-KKTSFHVTNLVPGNEYYFRVT 12468
Query: 696 AVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGY 752
AVN G P+ +P + PL+ PP L V +T + T+ W PP G A +DGY
Sbjct: 12469 AVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGY 12528
Query: 753 VLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKA 812
+ Y E + PA+ W ++ +TGL K RV A
Sbjct: 12529 ITSYREE----------------EQPADRW--TEYSVVKDLSLVVTGLKEGKKYKFRVAA 12570
Query: 813 VNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELT 872
NA G S P+ KE + PPKI +P + + G+ + + GKP P
Sbjct: 12571 RNAVGVSLPREAEGVYEAKEQLLPPKILMPEQI----TIKAGKKLRIEAHVYGKPHPTCK 12626
Query: 873 WKKDGAE-IDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDR 931
WKK E + + + + +++ +I+ I+ R SG Y L + +T I + ++D
Sbjct: 12627 WKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDA 12686
Query: 932 PGPPQ-IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSA 990
PGPPQ I D+ + +L+W P +DG + IT Y ++K D +W T + +TS
Sbjct: 12687 PGPPQPPFDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSC 12746
Query: 991 TITELVIGNEYYFRVFSENMCGLSEDATMTK 1021
+ +L+ G EY FRV +EN G+SE T K
Sbjct: 12747 RVGKLIPGQEYIFRVRAENRFGISEPLTSPK 12777
Score = 244 bits (623), Expect = 3e-64
Identities = 143/488 (29%), Positives = 242/488 (49%), Gaps = 34/488 (6%)
Query: 534 TVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSS----TLVIDIA 589
T+ V AG + +P G P P +WS+ D + RT +Y D++ +L I+ A
Sbjct: 19890 TLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDL-------RTRAYVDTTDSRTSLTIENA 19942
Query: 590 ERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGS 649
R+DSG Y + ++N A ++ VKV+D P PP TV +V + +++W+ P DGG+
Sbjct: 19943 NRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGA 20002
Query: 650 PILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPS 709
P+ Y IE+++ W+ + + C +++ + EG Y R+ N G+ P+
Sbjct: 20003 PVKNYHIEKREASKKAWVSVT-NNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETK 20061
Query: 710 RPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDE 769
SPP L V S++ +V++ W P+H G + + YV+E +G
Sbjct: 20062 EGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQ-------- 20113
Query: 770 NGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPIL 829
++W+ + T ++GL +++ F RV A N AG S+P+ P+L
Sbjct: 20114 ----------KNWVKC--AVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVL 20161
Query: 830 VKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKN-QINIR 888
+KE +EPP+I + T R G + + IP GKP P++T +DG + + N
Sbjct: 20162 IKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTE 20221
Query: 889 NSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWGEN 947
+ + I ++++ + +G+Y++ A I+I ++DRPGPP V I D+ E+
Sbjct: 20222 ITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDITEES 20281
Query: 948 VALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFS 1007
V L W PPK DG + +T Y + K + + W V RT + +L G EY FR+ +
Sbjct: 20282 VTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKA 20341
Query: 1008 ENMCGLSE 1015
EN G+S+
Sbjct: 20342 ENRFGISD 20349
Score = 244 bits (622), Expect = 4e-64
Identities = 157/500 (31%), Positives = 254/500 (50%), Gaps = 31/500 (6%)
Query: 522 PKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS 581
P + LD D V V AG +R+ +SG+PPP W+ ++ + + + E+ S
Sbjct: 10217 PDLQLDASVRDRIV-VHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEA---TIETTAIS 10272
Query: 582 STLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTE-VGDDWCIMNW 640
S++VI +R GVY + KNEAGE +I V V+D P P P + + ++ C + W
Sbjct: 10273 SSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTW 10332
Query: 641 EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAI 700
P DGGSPI Y IE+++ W + + + ++ + +I+G AY RI A N+I
Sbjct: 10333 FSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNA-TVQGLIQGKAYFFRIAAENSI 10391
Query: 701 GISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 757
G+ S V P+ V P L V VT TVT+ W PP + G + + YVLE
Sbjct: 10392 GMGPFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESR 10451
Query: 758 FEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAG 817
G+ + V N +L+ + K+T+ GL RV AVN G
Sbjct: 10452 LIGTEKFHK-----------------VTNDNLLSR-KYTVKGLKEGDTYEYRVSAVNIVG 10493
Query: 818 ASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDG 877
+P + ++PI K+ + PP + + K T RVGEA L + GKP+P+++W KD
Sbjct: 10494 QGKPSFCTKPITCKDELAPPTLHLDFRDKLTI--RVGEAFALTGRYSGKPKPKVSWFKDE 10551
Query: 878 AEI-DKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ 936
A++ + ++ +I+ + + KA+RS SGKY + V+ + ++DRPGPP
Sbjct: 10552 ADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPV 10611
Query: 937 -IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITEL 995
V ++V + + ++W PP DDG + IT Y I+K + W V +T+ +++L
Sbjct: 10612 GPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKL 10671
Query: 996 VIGNEYYFRVFSENMCGLSE 1015
+ G +Y FR+ +EN+ G+S+
Sbjct: 10672 LEGKDYIFRIHAENLYGISD 10691
Score = 239 bits (611), Expect = 8e-63
Identities = 151/488 (30%), Positives = 240/488 (49%), Gaps = 28/488 (5%)
Query: 530 DADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIA 589
D TVT+ AG LRL + +SG PPP WS+ + + TESY S L++D
Sbjct: 23146 DLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESY---SLLIVDKV 23202
Query: 590 ERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGS 649
R D+G Y I +N++G+ A++ VKV D P P + V EV D + WE P DGG+
Sbjct: 23203 NRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGA 23262
Query: 650 PILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPS 709
P+ Y +E K++ + R + C +T + ++EG Y R+ N GI +P S
Sbjct: 23263 PVNNYIVE-KREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETS 23321
Query: 710 RPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDE 769
+ V P L V VT +TVT+ W P + G + L GYVLE C G+
Sbjct: 23322 DAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGT-------- 23373
Query: 770 NGEAAYDLPAEDW--IVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQP 827
E W +V K + + T+T L + R++A N G SEP+
Sbjct: 23374 ----------ERWMKVVTLKPTV--LEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTA 23421
Query: 828 ILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI-DKNQIN 886
+ V+++ P I + ++T G V LVIP G+P P +W G+++ + ++
Sbjct: 23422 VTVQDLRVLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVT 23481
Query: 887 IRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWG 945
+ + IR+ +G+Y L++K + +I + I+D+PGPP +KI+++
Sbjct: 23482 VETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDA 23541
Query: 946 ENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRV 1005
++ ++W PP+ DG A ++GY +++ D W V E R++ T L GNEY FRV
Sbjct: 23542 TSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRV 23601
Query: 1006 FSENMCGL 1013
+ N G+
Sbjct: 23602 AATNRFGI 23609
Score = 239 bits (610), Expect = 1e-62
Identities = 152/526 (28%), Positives = 245/526 (46%), Gaps = 40/526 (7%)
Query: 508 YNVTLPAKVHVIDPPKIILDGLDADNT--------------VTVIAGNKLRLEIPISGEP 553
Y V+ K V DP +I L L AD+ + VI N + + +P +G P
Sbjct: 7059 YRVSAENKAGVSDPSEI-LGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYP 7117
Query: 554 PPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIK 613
P A W GDK ++E R++ ++ + LVI +ER D G+Y + L+N I
Sbjct: 7118 RPTATWCFGDK-VLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEID 7176
Query: 614 VKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDL 673
V V+ P P ++ D + WEPP DGGSP+ GY +E+++ W ++ D
Sbjct: 7177 VNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKV-MDF 7235
Query: 674 CKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPF---VPLAVTSPPTLLTVDSVT 730
+ F +++G Y ++ A N G +P+ P P V PP + T
Sbjct: 7236 VTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRT 7295
Query: 731 DTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLI 790
++ + W PP + G + + GY++E C GS + W+ + +
Sbjct: 7296 ANSIFLTWDPPKNDGGSRIKGYIVERCPRGS------------------DKWVACGEP-V 7336
Query: 791 DKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYI 850
+TK +TGL RVKA+N GAS+P ++ I + E P+I + L
Sbjct: 7337 AETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLT 7396
Query: 851 RRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKN-QINIRNSETDTIIFIRKAERSHSGKY 909
+ G + L GKP P++TW K + ++ +I I N + + I ++RS +G Y
Sbjct: 7397 VKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTY 7456
Query: 910 DLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQ 969
++ TA +++ ++D+PGPP I DV E+ LTW PP+DDG + IT Y ++
Sbjct: 7457 IIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVE 7516
Query: 970 KADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1015
+ S W + T+ T+L+ EY FRV +ENM G+ E
Sbjct: 7517 RRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGE 7562
Score = 239 bits (610), Expect = 1e-62
Identities = 138/399 (34%), Positives = 201/399 (50%), Gaps = 21/399 (5%)
Query: 620 PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTF 679
P PP P VT V D ++W P DGGSPILGY +ERK++ W ++ L F
Sbjct: 14954 PGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIF 15013
Query: 680 EPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWR 739
+ + +G+AYE R+ A N G SKPS PS P + L PP ++T TVT++W
Sbjct: 15014 KSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWA 15073
Query: 740 PPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITG 799
P++ G + Y++E DLP W+ AN I + +FT++G
Sbjct: 15074 KPEYTGGFKITSYIVE------------------KRDLPNGRWLKANFSNILENEFTVSG 15115
Query: 800 LPTDAKIFVRVKAVNAAGA-SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVN 858
L DA RV A NAAGA S P S I ++ +E PKI++ K T I + GEA
Sbjct: 15116 LTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVILKAGEAFR 15175
Query: 859 LVIPFQGKPRPELTWKKDGAEIDKN-QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDK 917
L G+P P + W KDG E++ ++ I+ ++ T + + + R SG Y L
Sbjct: 15176 LEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPG 15235
Query: 918 FVETASIDIQIIDRPGPPQ-IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSM 976
+++++DRPGPP+ + + +V E L+W PP DDG A I Y +QK + +
Sbjct: 15236 GFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRL 15295
Query: 977 EWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1015
W V T +T+L+ GNEY FRV + N G+ E
Sbjct: 15296 AWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGE 15334
Score = 239 bits (610), Expect = 1e-62
Identities = 162/609 (26%), Positives = 285/609 (46%), Gaps = 58/609 (9%)
Query: 429 DLKPLKILTPLTDQTVNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIH 486
D+KP + +V +G+++ ++ IS WTK+GLP++++ R+ V +
Sbjct: 16926 DVKPA-----FSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLT 16980
Query: 487 KLVIANALTEDEGDYVFAPDAYNVTLPAKVHVI-----DPPK--IILDGLDADNTVTVIA 539
L I +D G Y A + ++ DPPK + D + A++
Sbjct: 16981 TLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAES------ 17034
Query: 540 GNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRT-----ESYPDSSTLVIDIAERDDS 594
I +S PP + I++ T + +TL + +
Sbjct: 17035 -------ITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTE 17087
Query: 595 GVYHINLKNEAGEAHASIKVKVV-----DFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGS 649
+ I +N G++ A +V P PP P T + D ++ W P +GGS
Sbjct: 17088 YQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGS 17147
Query: 650 PILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPS 709
P++GY +ERK++ S W ++N + +T F+ + + EG+ YE R++A N +G+ K S S
Sbjct: 17148 PVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNS 17207
Query: 710 RPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDE 769
+V PP V +T++W P + G + + GY++E
Sbjct: 17208 ECYVARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVE-------------- 17253
Query: 770 NGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGA-SEPKYYSQPI 828
DLP W+ A+ + +T+FT++GL D + RV A NAAGA S+P + PI
Sbjct: 17254 ----KRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPI 17309
Query: 829 LVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKN-QINI 887
K+ +E P+I + + T + GE L GKP P + W + EI+++ + I
Sbjct: 17310 TAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEI 17369
Query: 888 RNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWGE 946
+N++ ++ ++ A R G+Y L+ ++ ++++++DRPGPP+ V++ V E
Sbjct: 17370 KNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSE 17429
Query: 947 NVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVF 1006
+LTW+PP DG + I+ Y ++K + + W V S +T+L+ GNEY FR+
Sbjct: 17430 KCSLTWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIM 17489
Query: 1007 SENMCGLSE 1015
+ N G+ E
Sbjct: 17490 AVNKYGVGE 17498
Score = 239 bits (610), Expect = 1e-62
Identities = 171/602 (28%), Positives = 283/602 (47%), Gaps = 51/602 (8%)
Query: 436 LTPLTDQTVNL--GKEICLKCEISENIP--GKWTKNGLPVQESDRLKVVHKGRIHKLVIA 491
L+ + +T+++ G+ + L I+ P W G ++ES+R+ V ++ KL I
Sbjct: 23435 LSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIR 23494
Query: 492 NALTEDEGDYVFAPDAYNVTLPA----KVHVIDPP-----KIILDGLDADNTVTVIAGNK 542
D G+Y + NVT KV ++D P I +D +DA + +
Sbjct: 23495 ETTIRDTGEYTL--ELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPE 23552
Query: 543 LRLEIPISG-----EPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVY 597
L P+SG + W +++ + + + + + R G Y
Sbjct: 23553 LDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSY 23612
Query: 598 HINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIE 657
L++E E +SI++ P PP + +V D + W PP DGGS + GY +E
Sbjct: 23613 ---LQSEVIECRSSIRI-----PGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVE 23664
Query: 658 RKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAV 717
RK+ ++ RW+R+N T + + EG+ YE R+ A+NA G KPS PS+P V +
Sbjct: 23665 RKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDP 23724
Query: 718 TSPPTLLTVDSVTDTT---VTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAA 774
+PP VTDTT V++ W P+ G + + GY++E ++ D++
Sbjct: 23725 IAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIE--------MQKVDQH---- 23772
Query: 775 YDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEII 834
+W N ++T+T LP A+ RV A NA G EP + V E++
Sbjct: 23773 ------EWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEML 23826
Query: 835 EPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDT 894
E P + ++ R G + L IP +GKP P W K+G +I K + I SET T
Sbjct: 23827 EYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAM-IATSETHT 23885
Query: 895 IIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWGENVALTWT 953
+ I++A+R SG YDL ++ + I +++I P P+ ++ +D+ +V ++W
Sbjct: 23886 ELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVSWR 23945
Query: 954 PPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL 1013
PP DDG A I GY +++ + W+T+ TS + L EY+FRV +EN G+
Sbjct: 23946 PPADDGGADILGYILERREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGI 24005
Query: 1014 SE 1015
S+
Sbjct: 24006 SK 24007
Score = 238 bits (607), Expect = 2e-62
Identities = 169/578 (29%), Positives = 277/578 (47%), Gaps = 44/578 (7%)
Query: 464 WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVH--VIDP 521
W K+G+ ++E R +++ L + + + D G YV T V+ V+D
Sbjct: 19518 WAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDK 19577
Query: 522 P-----KIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTE 576
P + ++GL A+ + I K S I EG ++
Sbjct: 19578 PGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQM--- 19634
Query: 577 SYPDSSTLVIDIAERDDSGVYHINLKNE--AGEAHASIKVKVVD---FPDPPVAPTVTEV 631
+S V + + ++ ++ + N+ GE S+ +K +D P PP + +T V
Sbjct: 19635 ----TSCKVTKLLKGNEY-IFRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSV 19689
Query: 632 GDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYE 691
+ + W P DGGS I GY IER++K S RW+R+N + + + EG YE
Sbjct: 19690 TKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYE 19749
Query: 692 VRIFAVNAIGISKPSMPS---RPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAG 748
R++A NA G+S PS S R P+ + SPP+ + TT+T+ W P G A
Sbjct: 19750 YRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAP 19809
Query: 749 LDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFV 808
+ GY +EY K+SD+ DW + + L T++TI+GL T A+
Sbjct: 19810 ITGYTVEY--------KKSDDT----------DWKTSIQSLRG-TEYTISGLTTGAEYVF 19850
Query: 809 RVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPR 868
RVK+VN GAS+P S P + KE E P I +++T I + G + + +PF+G+P
Sbjct: 19851 RVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPV 19910
Query: 869 PELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQI 928
P + W K ++ + + + +++ T + I A R+ SGKY L ++ + ++ +++
Sbjct: 19911 PNVLWSKPDTDL-RTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKV 19969
Query: 929 IDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRT 988
+D PGPP + ++DV E+ L+W P++DG A + Y I+K + W +V + +R
Sbjct: 19970 LDTPGPPTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCNRL 20029
Query: 989 SATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVI 1026
S +T L G YYFRV EN G+ A TKE I
Sbjct: 20030 SYKVTNLQEGAIYYFRVSGENEFGVGIPAE-TKEGVKI 20066
Score = 236 bits (603), Expect = 7e-62
Identities = 153/533 (28%), Positives = 261/533 (48%), Gaps = 43/533 (8%)
Query: 518 VIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTES 577
++ PP+ LD D T+ + AG +RL +P+ G PPPK WS+ + + + G + +S
Sbjct: 13382 ILIPPEGELDA-DLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIG-LDIKS 13439
Query: 578 YPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCI 637
+ L + + D+G Y + L+N G+ +I VKV+D P PPV TV E+ D
Sbjct: 13440 TDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAY 13499
Query: 638 MNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAV 697
+ WEPP DGGSPI+ Y ++++ + W + + C +T+F + EG +Y R+FA
Sbjct: 13500 VTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTE-CSKTSFRVANLEEGKSYFFRVFAE 13558
Query: 698 NAIGISKPSMPSRPFVPLAVTSPPTL-LTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEY 756
N GI P +R V + T P + L V SV+ ++ ++ W+ P G + + GYV+++
Sbjct: 13559 NEYGIGDPG-ETRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDF 13617
Query: 757 CFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAA 816
++EN W K L +++ L + RV A N
Sbjct: 13618 L---------TEEN----------KWQRVMKSL--SLQYSAKDLTEGKEYTFRVSAENEN 13656
Query: 817 GASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKK- 875
G P + ++ ++ + P + + Y+ + L IP +GKP P ++WKK
Sbjct: 13657 GEGTPSEIT--VVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKG 13714
Query: 876 DGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPG-P 934
+ ++++ +S +T + + ++S +GKY + +K + +I I+++ +PG P
Sbjct: 13715 EDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKPGIP 13774
Query: 935 PQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITE 994
+K ++V E + L W PPKDDG + IT Y ++K D + +W T +T+ +T
Sbjct: 13775 TGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAVQKTTFRVTR 13834
Query: 995 LVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAP 1047
L G EY FRV +EN G+ E K ++AR FD +AP
Sbjct: 13835 LHEGMEYTFRVSAENKYGVGEG---LKSEPIVAR----------HPFDVPDAP 13874
Score = 236 bits (603), Expect = 7e-62
Identities = 185/698 (26%), Positives = 312/698 (44%), Gaps = 80/698 (11%)
Query: 364 EVSEDDANVKWFK----NGEEII-------PGPKSRYRIRVEGKKHILIIEGATKADAAE 412
+VS+ A++ W K G ++ P ++ I E K ++ G + +
Sbjct: 17918 DVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQ 17977
Query: 413 YSVMTTG--GQSSAKL--------SVDLKPLKILTPLTDQTVNLGKEICLKCEI----SE 458
+ V G+S ++ + ++P + P ++ G+++ ++ +
Sbjct: 17978 FRVKAYNEKGKSDPRVLGVPVIAKDLTIQP-SLKLPFNTYSIQAGEDLKIEIPVIGRPRP 18036
Query: 459 NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAP--DAYNVTLPAKV 516
NI W K+G P++++ R+ V L I +D G Y A T V
Sbjct: 18037 NI--SWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSV 18094
Query: 517 HVIDPP-----KIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSG 571
V++ P + D + AD V IS EPP + I+E
Sbjct: 18095 IVLEKPGPPVGPVRFDEVSADFVV-------------ISWEPPAYTGGCQISNYIVEKRD 18141
Query: 572 RIRTESYPDSSTLV---IDIAERDDSGVYHINL--KNEAGE-AHASIKVKVVDFP----D 621
T + S+T+ I I + Y + +N G+ A K +V +P
Sbjct: 18142 TTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEPG 18201
Query: 622 PPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEP 681
PP P VT + D ++ W P DGG+ I+GY +E+K+K S W++LN ++T F+
Sbjct: 18202 PPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKT 18261
Query: 682 KKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPP 741
+ EG+ YE ++ A N +GI KPS S FV PP +T VT++W+ P
Sbjct: 18262 TGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIVITRNNVTLKWKKP 18321
Query: 742 DHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLP 801
+ G + + GY++E DLP W+ A+ + +T+FT++GL
Sbjct: 18322 AYDGGSKITGYIVE------------------KKDLPDGRWMKASFTNVLETEFTVSGLV 18363
Query: 802 TDAKIFVRVKAVNAAG-ASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLV 860
D + RV A NAAG SEP S I ++ I+ P + K + GE L
Sbjct: 18364 EDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGETFVLE 18423
Query: 861 IPFQGKPRPELTWKKDGAEIDKN--QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKF 918
+GKP P++ W KDG E+++ ++ I+++ T + ++ R+ G+Y L++
Sbjct: 18424 ADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGG 18483
Query: 919 VETASIDIQIIDRPGPPQ-IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSME 977
++ I ++++DRPGPP+ +K+ V E L W PP DG A I+ Y I+K + +
Sbjct: 18484 TKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLS 18543
Query: 978 WFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1015
W V + +T+L+ GNEY FRV + N G+ E
Sbjct: 18544 WTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGE 18581
Score = 234 bits (596), Expect = 5e-61
Identities = 171/604 (28%), Positives = 285/604 (47%), Gaps = 46/604 (7%)
Query: 428 VDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVVHKGRIHK 487
+DLK +LT T+ L E ++ + + K+ + S R+K+ + K
Sbjct: 11898 LDLKLSGVLTVKAGDTIRL--EAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSK 11955
Query: 488 LVIANALTEDEGDYVFAPD--AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRL 545
+ A D G YV A + A V+V+D P G + + ++ ++
Sbjct: 11956 FSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKP-----GPVRNLKIVDVSSDRCT- 12009
Query: 546 EIPISGEPPPKAMWSRGDKAIMEG--SGRIRTESYPDS----STLVIDIAERDDSGVYHI 599
+ +PP I+E + R+ +Y + T V + E ++ ++ +
Sbjct: 12010 ---VCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEY-IFRV 12065
Query: 600 NLKNEAG-----EAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGY 654
+N+ G E+ I D P P P VT+V + + W PP YDGG I GY
Sbjct: 12066 RAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGY 12125
Query: 655 FIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV- 713
F+E+K+K S+RW+ +N E + + ++ Y+ R+ A N IGI +PS+PSRP V
Sbjct: 12126 FLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVA 12185
Query: 714 --PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENG 771
P+ PPT V T ++T+ W P + G A + GYV+E K +D +
Sbjct: 12186 KDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEM------RPKIADAS- 12238
Query: 772 EAAYDLPAEDWIVANKDL-IDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILV 830
P E W N + + +FT+T L + + RV A N G P + I
Sbjct: 12239 ------PDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKP 12292
Query: 831 KEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAE--IDKNQINIR 888
KEI+EPP+I + +++ I R G + L +G+P P++TW+K G + + K Q+++
Sbjct: 12293 KEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDL- 12351
Query: 889 NSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENV 948
+T + I + R SGKY L + + ++++++D PGP +K+ DV +
Sbjct: 12352 -VDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSC 12410
Query: 949 ALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSE 1008
++W PP++DG + +T Y ++K + W TV +TS +T LV GNEYYFRV +
Sbjct: 12411 HVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAV 12470
Query: 1009 NMCG 1012
N G
Sbjct: 12471 NEYG 12474
Score = 233 bits (594), Expect = 8e-61
Identities = 202/725 (27%), Positives = 321/725 (44%), Gaps = 83/725 (11%)
Query: 332 STELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKW----FKNGEEIIP---- 383
S L +REP I V ++ ED +E++ EV+++ + W + G EII
Sbjct: 10400 SEALVIREP-ITVPERPED--------LEVK-EVTKNTVTLTWNPPKYDGGSEIINYVLE 10449
Query: 384 ----GPKSRYRIRVEGK-KHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTP 438
G + +++ + ++G + D EY V K S KP+
Sbjct: 10450 SRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDE 10509
Query: 439 LTDQTVNLGKEICLKCEISE------NIPGK------WTKNGLPVQESDRLKVVHKGRIH 486
L T++L L + E GK W K+ V E DR +
Sbjct: 10510 LAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATL 10569
Query: 487 KLVIANALTEDEGDYVFAPDAYNVTLPAK----VHVIDPPKIILDGLDADNTVTVIAGNK 542
L A D G Y + N T K V+V+D P + + D
Sbjct: 10570 ALEKIKAKRSDSGKYCVVVE--NSTGSRKGFCQVNVVDRPGPPVGPVSFDEVT------- 10620
Query: 543 LRLEIPISGEPPPKAMWSRGDKAIMEGSGRIR------TESYPDSSTLVIDIAERDDSGV 596
+ + IS +PP S+ I+E + T + ++ V + E D +
Sbjct: 10621 -KDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDY-I 10678
Query: 597 YHINLKNEAG--EAHASIKVKVVD---FPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPI 651
+ I+ +N G + S +K D PD P P VTEV D ++ W P +DGG PI
Sbjct: 10679 FRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKP-HDGGKPI 10737
Query: 652 LGYFIERKKKQSSRWMRLNFD-LCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSR 710
Y +E+++ S RW R+ D + T F ++EG YE R+ A N IGI PS PS+
Sbjct: 10738 TNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSK 10797
Query: 711 PFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQS 767
P P+A SPP T +V + W+PP H G + + GY++EY K
Sbjct: 10798 PVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEY-------QKVG 10850
Query: 768 DENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQP 827
DE A P + +TK+ +TGL RV AVNAAG S+P + +P
Sbjct: 10851 DEEWRRANHTP---------ESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEP 10901
Query: 828 ILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINI 887
+LVK+ +EPP++ + ++ + +VG+ + L +G P P++TWKK+ + + I
Sbjct: 10902 VLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAP-TKARI 10960
Query: 888 RNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGEN 947
+ + + IR A G Y L V+ +T S+ + ++D+PGPP+ +++ ++ ++
Sbjct: 10961 DVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDS 11020
Query: 948 VALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFS 1007
LTW P DDG + IT Y +++ D S +W + + S L GN+Y FRV +
Sbjct: 11021 CYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAA 11080
Query: 1008 ENMCG 1012
EN G
Sbjct: 11081 ENQYG 11085
Score = 233 bits (593), Expect = 1e-60
Identities = 172/611 (28%), Positives = 288/611 (47%), Gaps = 45/611 (7%)
Query: 241 LKRMRREEKKSAAFA-------KILDPAYQVDKGGR--VRFVVELADPKLEVKWYKNGQE 291
L R E KSAA +I++P ++ + V F ++ + +KW KNG+E
Sbjct: 6408 LTNHRGENVKSAANLIVEEEDLRIVEPLKDIETMEKKSVTFWCKVNRLNVTLKWTKNGEE 6467
Query: 292 IRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDT 351
+ + + + +L I +C D+ EY VTAG +K EL + E P + LED
Sbjct: 6468 VPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYIVTAGQDKSVAELLIIEAPTEFVEHLEDQ 6527
Query: 352 TAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAA 411
T + C++S + ANVKW++NG EI G K Y+ +G H LII+ D
Sbjct: 6528 TVTEFDDAVFSCQLSREKANVKWYRNGREIKEGKK--YKFEKDGSIHRLIIKDCRLDDEC 6585
Query: 412 EYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLP 470
EY+ +S A+L V+ P++I+ P D G ++ E++ + + +W +N +
Sbjct: 6586 EYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQWLRNNMV 6645
Query: 471 VQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLD 530
V + D+ +++ +G+IH+L I + D+G+Y F A + AK+ + PKI
Sbjct: 6646 VVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFI--AKDKEARAKLELAAAPKI----KT 6699
Query: 531 ADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAE 590
AD + V G L + +P P +A W + ++ + + ++ + ++ I A+
Sbjct: 6700 ADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKT----IDTTAEQTSFRILEAK 6755
Query: 591 RDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSP 650
+ D G Y I L+N+ G+A I +KV+D P P VTE D + WE P DGGS
Sbjct: 6756 KGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSK 6815
Query: 651 ILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIE-GVAYEVRIFAVNAIGISKPSMPS 709
I+GY +ER+ + W+ L D + F + + GV Y R+ A N +G +P
Sbjct: 6816 IIGYVVERRDIKRKTWV-LATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETD 6874
Query: 710 RPFVPLA---VTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQ 766
P + V PP +T+ V V++ W PP++ G A + YV+E TS +
Sbjct: 6875 NPVEARSKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIE--LRDKTSIR- 6931
Query: 767 SDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQ 826
+ A + AED D+++ +++ RV+A N G +P +
Sbjct: 6932 ----WDTAMTVRAEDLSATVTDVVEGQEYSF-----------RVRAQNRIGVGKPSAATP 6976
Query: 827 PILVKEIIEPP 837
+ V + IE P
Sbjct: 6977 FVKVADPIERP 6987
Score = 232 bits (592), Expect = 1e-60
Identities = 158/525 (30%), Positives = 252/525 (48%), Gaps = 40/525 (7%)
Query: 520 DPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWS---RGDKAIMEGSGRI--- 573
+ P++ +D + A + + AG+++R+ I G P PK+ W + KA+ +G I
Sbjct: 9501 EEPEVFID-IGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPED 9559
Query: 574 -RTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVG 632
+ E+ +SS ++I +R +G Y I KN+AG+ A+ +VKV+D P PP V+++
Sbjct: 9560 AQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDIT 9619
Query: 633 DDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEV 692
C ++W+ P DGG I GY IE++ W ++N D C TTF ++ Y
Sbjct: 9620 RGSCRLSWKMPDDDGGDRIKGYVIEKRTIDGKAWTKVNPD-CGSTTFVVPDLLSEQQYFF 9678
Query: 693 RIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGL 749
R+ A N GI P + P+ PP L + +T TV + W+PP + G + +
Sbjct: 9679 RVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPV 9738
Query: 750 DGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVR 809
Y++E T K+ E W NK +++ +FT+ L + R
Sbjct: 9739 THYIVECLAWDPTGTKK-------------EAWRQCNKRDVEELQFTVEDLVEGGEYEFR 9785
Query: 810 VKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRP 869
VKAVNAAG S+P P + PP I LK+ G VN+V +G P P
Sbjct: 9786 VKAVNAAGVSKPSATVGPCDCQRPDMPPSI----DLKEFMEVEEGTNVNIVAKIKGVPFP 9841
Query: 870 ELTW------KKDGAE---IDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVE 920
LTW K D E D + + +T T++ I ++ RS +G Y + +
Sbjct: 9842 TLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLV-IPQSRRSDTGLYTITAVNNLGTA 9900
Query: 921 TASIDIQIIDRPGPP-QIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF 979
+ + + ++ RPGPP +K E V + + L+W PPKDDG + IT Y I+K + W
Sbjct: 9901 SKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWV 9960
Query: 980 TVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESA 1024
V + TI +L+ G+EY FR+ ++N G+ E E+A
Sbjct: 9961 HVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETA 10005
Score = 232 bits (591), Expect = 2e-60
Identities = 174/651 (26%), Positives = 304/651 (46%), Gaps = 60/651 (9%)
Query: 386 KSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVN 445
K++Y+ R + + I + +D +++ LSV +K L TV
Sbjct: 12954 KAQYQFRAIARTAVNISPPSEPSDPV--TILAENVPPRIDLSVAMKSLL--------TVK 13003
Query: 446 LGKEICLKCEI-SENIPG-KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF 503
G +CL + + +P W K+G ++ ++ +K+ + + L + + +D GDY
Sbjct: 13004 AGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTI 13063
Query: 504 APDAYNVTLPA--KVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSR 561
+ + + A K+ V+D P G A + + ++ L S EPP + S
Sbjct: 13064 TAENSSGSKSATIKLKVLDKP-----GPPASVKINKMYSDRAML----SWEPPLEDGGSE 13114
Query: 562 GDKAIMEGSGRIRTESYPDSSTLVI---DIAERDDSGVYHINL--KNEAGEA-----HAS 611
I++ R S+T+ I + + + Y + +N+ G +
Sbjct: 13115 ITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPA 13174
Query: 612 IKVKVVDFP---DPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMR 668
I D P DPPV +T+ D ++W+PPA DGGSPI GY +E+++ Q+ W +
Sbjct: 13175 IAKNPYDPPGRCDPPVISNITK---DHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTK 13231
Query: 669 LNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLT 725
+N E T + + EG YE R+ A+N G KPS S+ P PP
Sbjct: 13232 VNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPK 13291
Query: 726 VDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVA 785
V T ++V++ W P + G + + GY++E K++D + +LP
Sbjct: 13292 VYDTTRSSVSLSWGKPAYDGGSPIIGYLVE--------VKRADSDNWVRCNLPQN----- 13338
Query: 786 NKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHL 845
+ KT+F +TGL D + RV AVN G S+P K+I+ PP+ + L
Sbjct: 13339 ----LQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADL 13394
Query: 846 KQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI-DKNQINIRNSETDTIIFIRKAERS 904
++T I R G + L +P +G+P P++TW K + D+ ++I++++ DT + +
Sbjct: 13395 RKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKY 13454
Query: 905 HSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAIT 964
+GKY L ++ + +I ++++D PGPP V ++++ ++ +TW PP DG + I
Sbjct: 13455 DAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPII 13514
Query: 965 GYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1015
Y +QK D + W TV +TS + L G Y+FRVF+EN G+ +
Sbjct: 13515 NYVVQKRDAERKSWSTVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGD 13565
Score = 229 bits (585), Expect = 9e-60
Identities = 149/513 (29%), Positives = 245/513 (47%), Gaps = 28/513 (5%)
Query: 506 DAYNVTLPAK-VHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDK 564
D+ VT K V + P++ +D + T V AG +RL I G P P A+WS+ D
Sbjct: 22033 DSCEVTGTIKAVDRLTAPELDIDA-NFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDS 22091
Query: 565 AIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPV 624
+ + T+S+ STL ++ R+D+G Y + ++N +G + VKV+D P PP
Sbjct: 22092 NLSLRADIHTTDSF---STLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGPPG 22148
Query: 625 APTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKM 684
T +V + W+ P DGG+ I Y +E+++ W ++ + C F+ +
Sbjct: 22149 PITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVIS-EKCTRQIFKVNDL 22207
Query: 685 IEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHI 744
EGV Y R+ AVN G+ +P P V +PP L V + ++ + W PDH
Sbjct: 22208 AEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHD 22267
Query: 745 GAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDA 804
G + + GY+LE +GS + W+ A + FT+ L
Sbjct: 22268 GGSRITGYLLEMRQKGS------------------DFWVEAGH--TKQLTFTVERLVEKT 22307
Query: 805 KIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQ 864
+ RVKA N AG SEP+ +++KE P + Q + G + +P
Sbjct: 22308 EYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPIS 22367
Query: 865 GKPRPELTWKKDGAEI-DKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETAS 923
G+P P++TWK + + + ++++I ++ T + ++ + R SG+Y L ++ V+T S
Sbjct: 22368 GRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFS 22427
Query: 924 IDIQIIDRPGP-PQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVI 982
+ + +I RPGP +++ V E+ L+W PKD G IT Y ++K + + W V
Sbjct: 22428 VTVVVIGRPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVN 22487
Query: 983 EHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1015
RT +T L EY FRV SEN G+S+
Sbjct: 22488 SSVKRTQIKVTHLTKYMEYSFRVSSENRFGVSK 22520
Score = 229 bits (584), Expect = 1e-59
Identities = 159/586 (27%), Positives = 270/586 (46%), Gaps = 42/586 (7%)
Query: 465 TKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKI 524
+++G+P++ + R + + ++T D G Y + T A ++++
Sbjct: 20206 SRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIV----- 20260
Query: 525 ILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIM---EGSGRIRTESYPDS 581
+LD T V+ + + + EPP S+ I+ E S + TE
Sbjct: 20261 VLDR-PGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATV 20319
Query: 582 STLVIDIAERDDSGVYHINLKNE--------AGEAHASIKVKVVDFPDPPVAPTVTEVGD 633
+ ++ + + Y +K E A ++K+ P PP P VT V
Sbjct: 20320 ARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTT-PGPPSTPWVTNVTR 20378
Query: 634 DWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVR 693
+ + W P +GGS ++GY +E K + S W + N + + T F+ + G+ YE R
Sbjct: 20379 ESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFR 20438
Query: 694 IFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYV 753
++A NA G+ KPS PS P + + PP + + ++ +V++ W+ P G + + GY+
Sbjct: 20439 VYAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYI 20498
Query: 754 LEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAV 813
+E DLP W A+ + +T+F I+GL +++ RV A
Sbjct: 20499 VE------------------RRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFAR 20540
Query: 814 NAAGA-SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELT 872
NA G+ S P PI + P I +P + R G +V L GKP P +
Sbjct: 20541 NAVGSISNPSEVVGPITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIE 20600
Query: 873 WKKDGAEIDKNQINIRNSETD-TIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDR 931
W KD E+ N + + TD I I+ A+R +SG Y+L+++ +A+I +QI+D+
Sbjct: 20601 WYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDK 20660
Query: 932 PGPP-QIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSA 990
PGPP ++ + V E + L W PP DDG A IT Y ++K + + W V EH
Sbjct: 20661 PGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVSEHLEECII 20720
Query: 991 TITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNP 1036
T T+++ GNEY FRV + N G+ E + +V+A++ + P
Sbjct: 20721 TTTKIIKGNEYIFRVRAVNKYGIGEP---LESDSVVAKNAFVTPGP 20763
Score = 228 bits (581), Expect = 3e-59
Identities = 172/638 (26%), Positives = 274/638 (42%), Gaps = 44/638 (6%)
Query: 394 EGKKHILIIEGATKADAAEYSVMTTGGQSSAKL-SVDLKPLKILTPLTDQTVNLGKEICL 452
EGK++ + + S +T + +DLK L L L + N +I +
Sbjct: 13642 EGKEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPI 13701
Query: 453 KCEISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTL 512
K + + ++ W K P+ R+ V L++ + D G Y T
Sbjct: 13702 KGKPAPSV--SWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTK 13759
Query: 513 PA--KVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGS 570
+ V+ P I + D VT A + + PP S I+E
Sbjct: 13760 EGTISIKVVGKPGIPTGPIKFDE-VTAEA-------MTLKWAPPKDDGGSEITNYILEKR 13811
Query: 571 GRIRTE-----SYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVV-----DFP 620
+ + S +T + + ++ +N+ G +V D P
Sbjct: 13812 DSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVP 13871
Query: 621 DPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFE 680
D P P + +V D + W P GGSPI GY +E K++ S W R N + F+
Sbjct: 13872 DAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFK 13931
Query: 681 PKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRP 740
+ EG+ YE R+ A+N G+ KPS+PS P V L PP V ++T +VT+ W
Sbjct: 13932 VTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTE 13991
Query: 741 PDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGL 800
P + G L GY++E DLP++ W+ AN + + FT+T L
Sbjct: 13992 PKYDGGHKLTGYIVE------------------KRDLPSKSWMKANHVNVPECAFTVTDL 14033
Query: 801 PTDAKIFVRVKAVNAAGA-SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNL 859
K R++A N AGA S P ++ I+ K+ E P I + +K + G+ + L
Sbjct: 14034 VEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVL 14093
Query: 860 -VIPFQGKPRPELTWKKDGAEIDKNQI-NIRNSETDTIIFIRKAERSHSGKYDLQVKVDK 917
I GKP P+ +W K G +I + I I ++ T +++ I+ A R +G+Y +
Sbjct: 14094 NAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPF 14153
Query: 918 FVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSME 977
+ + + ++D PGPP V+I +V E LTWTPP +DG + I Y ++K + +
Sbjct: 14154 GTKVEHVKVTVLDVPGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLL 14213
Query: 978 WFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1015
W V E T+L+ GNEY FRV + N G E
Sbjct: 14214 WTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYGKGE 14251
Score = 227 bits (579), Expect = 4e-59
Identities = 156/571 (27%), Positives = 260/571 (45%), Gaps = 50/571 (8%)
Query: 464 WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF--APDAYNVTLPAKVHVIDP 521
W K+G ++E+ R+ V + L I A ED G Y + A ++T+P + V+D
Sbjct: 19123 WRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDR 19182
Query: 522 P----KIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTES 577
P I +D + D+ I IS PP + I+E T
Sbjct: 19183 PGPPGPIRIDEVSCDS-------------ITISWNPPEYDGGCQISNYIVEKKETTSTTW 19229
Query: 578 YPDSSTLV---IDIAERDDSGVYHINL-------KNEAGEAHASIKVKVVDFPDPPVAPT 627
+ S + I I Y + K+ E+ A + P PP P
Sbjct: 19230 HIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPK 19289
Query: 628 VTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEG 687
V ++ W+ P DGGS ++GY +E K++ S W + N L +T + + EG
Sbjct: 19290 VVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIADTQMKVSGLDEG 19349
Query: 688 VAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAA 747
+ YE R++A N GI K S P PP V ++T +V+++W P + G A
Sbjct: 19350 LMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGA 19409
Query: 748 GLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIF 807
+ GY++E +LP W+ N I +T F +T L D +
Sbjct: 19410 KITGYIVE------------------RRELPDGRWLKCNYTNIQETYFEVTELTEDQRYE 19451
Query: 808 VRVKAVNAA-GASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGK 866
RV A NAA SEP + PI+VK+ +EPP++ + + + + GE + + G+
Sbjct: 19452 FRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGR 19511
Query: 867 PRPELTWKKDGAEIDKN-QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASID 925
P P ++W KDG EI++ + I +++ T++ ++ R +G+Y L +K + +++
Sbjct: 19512 PLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVN 19571
Query: 926 IQIIDRPGPPQ-IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEH 984
+++D+PGPP ++I + E +L+W P++DG A I Y ++K + + W
Sbjct: 19572 CKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGE 19631
Query: 985 YHRTSATITELVIGNEYYFRVFSENMCGLSE 1015
TS +T+L+ GNEY FRV N G+ E
Sbjct: 19632 LQMTSCKVTKLLKGNEYIFRVTGVNKYGVGE 19662
Score = 226 bits (575), Expect = 1e-58
Identities = 154/509 (30%), Positives = 238/509 (46%), Gaps = 33/509 (6%)
Query: 519 IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESY 578
++PP++ILD A + G+ LRL I G P PK W + D+ + + R +
Sbjct: 10908 LEPPELILDANMAREQ-HIKVGDTLRLSAIIKGVPFPKVTWKKEDR---DAPTKARIDVT 10963
Query: 579 PDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIM 638
P S L I A +D G+Y + ++N AG S+KV V+D P PP V+E+ D C +
Sbjct: 10964 PVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYL 11023
Query: 639 NWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVN 698
W+ P DGGS I Y +ER+ S++W L+ K++ F K + EG Y R+ A N
Sbjct: 11024 TWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHF-AKHLNEGNQYLFRVAAEN 11082
Query: 699 AIG---ISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLE 755
G + P + PL PP L V T V++ W PD G + + GY++E
Sbjct: 11083 QYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVE 11142
Query: 756 YCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNA 815
Y EG+ +DWI + + +TGL RVKA N
Sbjct: 11143 YQEEGT------------------QDWI--KFKTVTNLECVVTGLQQGKTYRFRVKAENI 11182
Query: 816 AGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKK 875
G P + PI +E + PP + + L + + + G V +G P P W
Sbjct: 11183 VGLGLPD-TTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTT 11241
Query: 876 DGAEIDKNQ-INIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGP 934
DG+EI ++ + +++ I+ R +G+Y + V +T ++ + ++D PGP
Sbjct: 11242 DGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGP 11301
Query: 935 PQ-IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATIT 993
P + I DV E++ ++W PPKDDG + + Y ++K D + W V +T I
Sbjct: 11302 PTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIP 11361
Query: 994 ELVIGNEYYFRVFSENMCGLSE--DATMT 1020
L G EY FRV +EN G+ D+T T
Sbjct: 11362 HLQKGCEYVFRVRAENKIGVGPPLDSTPT 11390
Score = 224 bits (572), Expect = 3e-58
Identities = 142/494 (28%), Positives = 240/494 (48%), Gaps = 29/494 (5%)
Query: 529 LDAD--NTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVI 586
LDA+ T+ V AG +R+ +PI G P P+ W++ + + + TES+ + L+I
Sbjct: 14473 LDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESF---TLLII 14529
Query: 587 DIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYD 646
R D+G + + ++N AG+ + V+V+D P P + T++ D ++W+ P D
Sbjct: 14530 PECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLID 14589
Query: 647 GGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPS 706
GGS I Y +E+++ + C + T++ + EG Y R+ A N GI +P+
Sbjct: 14590 GGSRITNYIVEKREATRKSYSTATTK-CHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPT 14648
Query: 707 MPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQ 766
+ P SPP L + +T +TV++ W P H G + + GYV+E +GS
Sbjct: 14649 ETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGS----- 14703
Query: 767 SDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQ 826
+ W + + + + L + +V AVN+AG S P+ S+
Sbjct: 14704 -------------DQW--THITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPR-ESR 14747
Query: 827 PILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ-I 885
P++VKE P++ + ++ I + G+ + + IP G+P+P +TWKK + + Q +
Sbjct: 14748 PVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRV 14807
Query: 886 NIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVW 944
N + T TI+ I + RS SG Y L + I IQ+ D PGPP +K ++V
Sbjct: 14808 NFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVS 14867
Query: 945 GENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFR 1004
+ V +W PP++DG I+ Y ++ S W + RT+ T L G EY FR
Sbjct: 14868 SDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIRTTYKATRLTTGLEYQFR 14927
Query: 1005 VFSENMCGLSEDAT 1018
V ++N G+ T
Sbjct: 14928 VKAQNRYGVGPGIT 14941
Score = 224 bits (570), Expect = 5e-58
Identities = 165/572 (28%), Positives = 264/572 (46%), Gaps = 51/572 (8%)
Query: 464 WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV--FAPDAYNVTLPAKVHVIDP 521
W K+ +P++++ R+ L I +A ED G YV A V V+D
Sbjct: 15876 WHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDK 15935
Query: 522 P-----KIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTE 576
P + +D + AD+ I +S PP S + I+E T
Sbjct: 15936 PGPPTGPVKMDEVTADS-------------ITLSWGPPKYDGGSSINNYIVEKRDTSTTT 15982
Query: 577 SYPDSSTLVIDI--AERDDSGV---YHINLKNEAGEA-HASIKVKVVDF----PDPPVAP 626
S+T+ A R +G + I +N G++ + + + V + P PP P
Sbjct: 15983 WQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTP 16042
Query: 627 TVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIE 686
VT D + W P DGGS ++GY +ERK++ S W++LN +T F+ + E
Sbjct: 16043 VVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEE 16102
Query: 687 GVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGA 746
GV YE R+ A N +GI KPS S +V PP VT +VT++W+ P + G
Sbjct: 16103 GVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGG 16162
Query: 747 AGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKI 806
+ + GY++E +LP W+ A+ I T F +TGL D +
Sbjct: 16163 SKITGYIVE------------------KKELPEGRWMKASFTNIIDTHFEVTGLVEDHRY 16204
Query: 807 FVRVKAVNAAGA-SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQG 865
RV A NAAG SEP + I ++ ++PP+I + K T + GE+ + G
Sbjct: 16205 EFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYG 16264
Query: 866 KPRPELTWKKDGAEIDKN-QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASI 924
KP P + W K E+ ++ I++++ T + ++ A R SG Y L+ K + ++
Sbjct: 16265 KPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTV 16324
Query: 925 DIQIIDRPGPPQ-IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIE 983
+++++DRPGPP+ V I V E L W PP DG + I Y +++ + + W V
Sbjct: 16325 NVKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDA 16384
Query: 984 HYHRTSATITELVIGNEYYFRVFSENMCGLSE 1015
+ S +T+L+ GNEY FR+ + N G+ E
Sbjct: 16385 NVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGE 16416
Score = 220 bits (560), Expect = 7e-57
Identities = 161/544 (29%), Positives = 248/544 (45%), Gaps = 66/544 (12%)
Query: 520 DPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYP 579
+ P+I LD + +TV AG K+ L ++G+P PK W++ D I++ RI E+ P
Sbjct: 7381 EAPEIFLD-VKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADM-ILKQDKRITIENVP 7438
Query: 580 DSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMN 639
ST+ I ++R D+G Y I N G A A ++V V+D P PP A +T+V ++ C++
Sbjct: 7439 KKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLT 7498
Query: 640 WEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNA 699
W PP DGGS I Y +ER+ S W +L+ K+T F+ K+I Y R+ A N
Sbjct: 7499 WNPPRDDGGSKITNYVVERRATDSEVWHKLS-STVKDTNFKATKLIPNKEYIFRVAAENM 7557
Query: 700 IGISKP--SMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 757
G+ +P + P PPT L +T VT+ W PD G + + GY +E
Sbjct: 7558 YGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVE-- 7615
Query: 758 FEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAG 817
D + W+ NK + T + + GL K RV A N AG
Sbjct: 7616 ----------------RLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAG 7659
Query: 818 ASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKK-- 875
+P ++PIL+K+ I+PP +K GK L W K
Sbjct: 7660 PGKPSKSTEPILIKDPIDPPWPPGKPTVKDV----------------GKTSVRLNWTKPE 7703
Query: 876 --DGAEIDKNQINIRNSETDTIIFIRKAE-----------RSHSGKYDLQVK-VDKFVET 921
GA+I+ I + + TD ++R AE +Y +V+ V+K E+
Sbjct: 7704 HDGGAKIESYVIEMLKTGTDE--WVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGES 7761
Query: 922 ASID-------IQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKK 974
+ + + P PP+ +++ ++ L WT P+ DG + IT Y ++K D +
Sbjct: 7762 EPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVR 7821
Query: 975 SMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYK 1034
W TV T T+T L G+ Y FRV +EN G S+ + E +V+A+D
Sbjct: 7822 RKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEI--EDSVLAKDTFTTP 7879
Query: 1035 NPVY 1038
P Y
Sbjct: 7880 GPPY 7883
Score = 219 bits (559), Expect = 9e-57
Identities = 174/636 (27%), Positives = 290/636 (45%), Gaps = 67/636 (10%)
Query: 428 VDLKPLKILTPLTDQTV-NLGKEICLKCEISENIPG--KWTKNGLPVQESDRLKVVHKGR 484
V+ +K+ D + G+ L+ ++S P +W+K+G ++ + +L++
Sbjct: 15151 VEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADF 15210
Query: 485 IHKLVIANALTEDEGDYV--------FAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVT 536
LV ++ D G Y FA +NV V+D P + VT
Sbjct: 15211 STNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVK------VLDRP----GPPEGPLAVT 15260
Query: 537 VIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIR-----TESYPDSSTLVIDIAER 591
+ K L S PP ++ D I++ R S + L + +
Sbjct: 15261 EVTSEKCVL----SWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLK 15316
Query: 592 DDSGVYHINLKNEAG-----EAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYD 646
+ ++ + N+ G E+ + V PDPP P VT + D ++ W P D
Sbjct: 15317 GNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSD 15376
Query: 647 GGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPS 706
GGS I+ Y +ER+ K RW++ N + ++ + EG YE RI A NA GIS PS
Sbjct: 15377 GGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPS 15436
Query: 707 MPSRPFVPLAVT----SPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGST 762
P+ PF T PP V + +++++ W P + G + + GY++E
Sbjct: 15437 -PTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIA----- 15490
Query: 763 SAKQSDENGEAAYDLPAED-W-IVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASE 820
LP ED W IV + T +TITGL + + +R+ A+N+ G E
Sbjct: 15491 --------------LPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGE 15536
Query: 821 PKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKD-GAE 879
P ++ + PP+I + L++ R + L +P +G+P PE+ W +D G
Sbjct: 15537 PALVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGES 15596
Query: 880 IDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVK 939
+DK +I ++ + T++ + R SGKY L V+ ++A ++++++D PGPPQ +K
Sbjct: 15597 LDK--ASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLK 15654
Query: 940 IEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGN 999
+++V +V LTW PP DG + I Y ++K + + TV + H+TS + +L G
Sbjct: 15655 VKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGC 15714
Query: 1000 EYYFRVFSENMCGL---SEDATMTKESAVIARDGKI 1032
YYFRV +EN G+ +E A K S GKI
Sbjct: 15715 SYYFRVLAENEYGIGLPAETAESVKASERPLPPGKI 15750
Score = 219 bits (557), Expect = 2e-56
Identities = 163/601 (27%), Positives = 258/601 (42%), Gaps = 40/601 (6%)
Query: 430 LKPLKILTPLTDQTVNLGKEICLKCEI--SENIPGKWTKNGLPVQESDRLKVVHKGRIHK 487
L P KIL P T+ GK++ ++ + + KW K V S L V
Sbjct: 12592 LLPPKILMP-EQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSI 12650
Query: 488 LVIANALTEDEGDYVFAPDAYNVTLPAKVHVI-----DPPKIILDGLDADNTVTVIAGNK 542
L+I + +D G Y + + T K+ V+ PP+ D D D
Sbjct: 12651 LIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADAC-----S 12705
Query: 543 LRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLK 602
L IP+ + + G S +S V + + ++ + +
Sbjct: 12706 LSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEY-IFRVRAE 12764
Query: 603 NEAGEAHASIKVKVV-----DFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIE 657
N G + K+V P P VT+V D + W+ P DGGSPI+GY IE
Sbjct: 12765 NRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIE 12824
Query: 658 RKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAV 717
RK++ S W++ N L + T + ++EG+ Y RI+A+N G S PS P+
Sbjct: 12825 RKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMP 12884
Query: 718 TSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDL 777
PP V VT +TV++ W P H G + + GY +E C L
Sbjct: 12885 VDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEAC------------------KL 12926
Query: 778 PAEDWIVAN--KDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIE 835
P + W+ N I + ++T TGL A+ R A A S P S P+ +
Sbjct: 12927 PGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENV 12986
Query: 836 PPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ-INIRNSETDT 894
PP+I + +K + G V L GKP P ++WKKDG + + I +
Sbjct: 12987 PPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLC 13046
Query: 895 IIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTP 954
+ + R SG Y + + ++A+I ++++D+PGPP VKI ++ + L+W P
Sbjct: 13047 TLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEP 13106
Query: 955 PKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLS 1014
P +DG + IT Y + K + W V TS ++ +L+ G+EY FR+ +EN G+
Sbjct: 13107 PLEDGGSEITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVG 13166
Query: 1015 E 1015
+
Sbjct: 13167 D 13167
Score = 219 bits (557), Expect = 2e-56
Identities = 151/565 (26%), Positives = 257/565 (45%), Gaps = 42/565 (7%)
Query: 464 WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPD--AYNVTLPAKVHVIDP 521
W K+GLP++ES+ ++ L I NA E G Y D + +P V + P
Sbjct: 21292 WLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGP 21351
Query: 522 PK-----IILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTE 576
P I D + AD+ + L ++P +S + + + ++
Sbjct: 21352 PSKPKGPIRFDEIKADSVI-------LSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCS 21404
Query: 577 SYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVD-----FPDPPVAPTVTEV 631
S ++ V ++ +D + + +N G + + +V P PP P + V
Sbjct: 21405 SVARTTFKVPNLV-KDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNV 21463
Query: 632 GDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYE 691
D + W+ P YDGGS + G+ +E+K++ S W ++N + ++EG+ Y+
Sbjct: 21464 TSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQ 21523
Query: 692 VRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDG 751
R++A N+ G+S PS PS+ + ++ PP VT T+T++W PP G + + G
Sbjct: 21524 FRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVG 21583
Query: 752 YVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVK 811
Y +E +Q +E W+ N + + ++T+TGL + R+
Sbjct: 21584 YSIE--------KRQGNER-----------WVRCNFTDVSECQYTVTGLSPGDRYEFRII 21624
Query: 812 AVNAAGA-SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPE 870
A NA G S P S I+ ++ PP + I + GE++ + QG+P P
Sbjct: 21625 ARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPR 21684
Query: 871 LTWKKDGAEIDKN-QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQII 929
+TW KDG EI+K + I + T +F+R A R H G Y ++ K A I +++
Sbjct: 21685 VTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 21744
Query: 930 DRPGP-PQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRT 988
D PG ++ ++ GE + L W P +DG A IT Y I+K + + W + +
Sbjct: 21745 DTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQ 21804
Query: 989 SATITELVIGNEYYFRVFSENMCGL 1013
S T +L+ GNEY FRV + N G+
Sbjct: 21805 SYTAIKLINGNEYQFRVSAVNKFGV 21829
Score = 216 bits (551), Expect = 8e-56
Identities = 161/592 (27%), Positives = 267/592 (45%), Gaps = 52/592 (8%)
Query: 463 KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNV----TLPAKVHV 518
+W K + + RL++ L + +A+ D G+Y+ A NV ++ V V
Sbjct: 16271 QWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILK--AKNVAGERSVTVNVKV 16328
Query: 519 IDPP-----KIILDGLDADNTVTVIA-----GNKLRLEIPISGEPPPKAMWSRGDKAIME 568
+D P +++ G+ A+ G + + + +W+ D +
Sbjct: 16329 LDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQT 16388
Query: 569 GSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTV 628
S ++ + T I + G E E+ + PD P AP V
Sbjct: 16389 LSCKVTKLLEGNEYTFRIMAVNKYGVG--------EPLESEPVVAKNPFVVPDAPKAPEV 16440
Query: 629 TEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGV 688
T V D I+ WE PA DGGS ILGY +E++ K+ RW R + L E +IE
Sbjct: 16441 TTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENH 16500
Query: 689 AYEVRIFAVNAIGISKPSMPS---RPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIG 745
YE R+ A NA G+S+PS PS + P+ PP V +T ++V + W P + G
Sbjct: 16501 DYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPIYDG 16560
Query: 746 AAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDL-IDKTKFTITGLPTDA 804
+ GY++E C D+ +W + I+KT + L
Sbjct: 16561 GCEIQGYIVEKC------------------DVSVGEWTMCTPPTGINKTNIEVEKLLEKH 16602
Query: 805 KIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQ 864
+ R+ A+N AG E PI+V+E +E P I + L++ R G ++ L +P +
Sbjct: 16603 EYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIK 16662
Query: 865 GKPRPELTW-KKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETAS 923
G+P PE+ W K DG D I++ +S T + + R SGKY L ++ ++A
Sbjct: 16663 GRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLV--LDNVNRYDSGKYTLTLENSSGTKSAF 16720
Query: 924 IDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIE 983
+ ++++D P PP +K+ ++ ++V++TW PP DG + I Y ++K + + V+
Sbjct: 16721 VTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVT 16780
Query: 984 HYHRTSATITELVIGNEYYFRVFSENMCGL---SEDATMTKESAVIARDGKI 1032
+ H+ S I +L G YYFRV +EN G+ ++ A K + V GKI
Sbjct: 16781 NCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKI 16832
Score = 216 bits (550), Expect = 1e-55
Identities = 154/518 (29%), Positives = 249/518 (48%), Gaps = 36/518 (6%)
Query: 505 PDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDK 564
P N + AK +++ P+I LD + +V AG +++ IP G PPP W R D+
Sbjct: 20948 PIEMNEPVQAK-DILEAPEIDLD-VALRTSVIAKAGEDVQVLIPFKGRPPPTVTW-RKDE 21004
Query: 565 AIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHAS-IKVKVVDFPDPP 623
+ R E+ SS L I R+D+G Y + ++N GE +S + VKV+D P
Sbjct: 21005 KNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAAC 21064
Query: 624 VAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKK 683
V V + W+PP DGGSPI+ Y IE++ W ++ C T+F+
Sbjct: 21065 QKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHK-CSSTSFKLID 21123
Query: 684 MIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDH 743
+ E + R+ A N IGI +P + P V +P L++ T T+V + W PD
Sbjct: 21124 LSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDF 21183
Query: 744 IGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKT-KFTITGLPT 802
G + + YV+E +G + W A I KT + ++ L
Sbjct: 21184 DGGSVITEYVVERKGKGE------------------QTWSHAG---ISKTCEIEVSQLKE 21222
Query: 803 DAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIP 862
+ + RV A N G S+P PI VKE+I P++ + R+G V+L +P
Sbjct: 21223 QSVLEFRVFAKNEKGLSDPVTIG-PITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELP 21281
Query: 863 FQGKPRPELTWKKDGAEIDKNQ-INIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVET 921
++GKP+P ++W KDG + +++ + +E + I+ A++ H GKY V +D V
Sbjct: 21282 YKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYT--VILDNAVCR 21339
Query: 922 ASIDIQIIDRPGPPQI----VKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSME 977
++ I +I GPP ++ +++ ++V L+W P+D+G IT Y+I+K +
Sbjct: 21340 IAVPITVITL-GPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTN 21398
Query: 978 WFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1015
W V RT+ + LV EY FRV +EN G+S+
Sbjct: 21399 WKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQ 21436
Score = 214 bits (546), Expect = 3e-55
Identities = 142/494 (28%), Positives = 224/494 (45%), Gaps = 36/494 (7%)
Query: 573 IRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG-----EAHASIKVKVVDFPDPPVAPT 627
+ S P T I V+ I +N+ G ++ + P P PT
Sbjct: 9960 VHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPT 10019
Query: 628 VTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETT----FEPKK 683
V+ V + +NWE P YDGGSP+ GY++E K S RW R+N D K T ++
Sbjct: 10020 VSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKVTG 10079
Query: 684 MIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRP 740
+IEG Y+ R++A+NA G+ S+PS P P+A PP V T ++ + W P
Sbjct: 10080 LIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPP-FPKVTDWTKSSADLEWSP 10138
Query: 741 PDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGL 800
P G + + GY++EY EG E+W + TK +TGL
Sbjct: 10139 PLKDGGSKVTGYIVEYKEEGK------------------EEWEKGKDKEVRGTKLVVTGL 10180
Query: 801 PTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLV 860
A RV+AVN AG EP + I +K+ + P +++ ++ + G + ++
Sbjct: 10181 KEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRII 10240
Query: 861 IPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVE 920
GKP P +TW + + + + I + + + I+ +RSH G Y L K +
Sbjct: 10241 AYVSGKPPPTVTWNMNERTLPQ-EATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGER 10299
Query: 921 TASIDIQIIDRPGPPQIVKI-EDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF 979
+I + ++D PGP + ++ E+ LTW P+DDG + IT Y I+K + W
Sbjct: 10300 KKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWT 10359
Query: 980 TVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYE 1039
V R +AT+ L+ G Y+FR+ +EN G+ T E+ VI + + P E
Sbjct: 10360 PVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMG-PFVETSEALVIREPITVPERP--E 10416
Query: 1040 DFDFSEAPMFTQPL 1053
D + E T L
Sbjct: 10417 DLEVKEVTKNTVTL 10430
Score = 211 bits (537), Expect = 3e-54
Identities = 160/553 (28%), Positives = 257/553 (46%), Gaps = 70/553 (12%)
Query: 502 VFAPDAYNVTLPAKV--HVI--DP---PKIILDGLDADNTVTVIAGNKLRLEIPISGEPP 554
V A +A V+ P+++ +V+ DP P I L+ D + VI G KL + +P P
Sbjct: 8055 VRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHD----IIVIEGEKLSIPVPFRAVPV 8110
Query: 555 PKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKV 614
P W + K + + S R+ ++ S+ L + + R D+G+Y I L+N+ G A ASI V
Sbjct: 8111 PTVSWHKDGKEV-KASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINV 8169
Query: 615 KVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLC 674
KV+ P P +++ C + WEPP +DGG+PIL Y +ER++ ++ +
Sbjct: 8170 KVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGEN 8229
Query: 675 KETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTD 731
K ++ K +I Y R+ AVN +G + P + P PP + V + T
Sbjct: 8230 K-LSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTA 8288
Query: 732 TTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLID 791
+T+ W+PP + G + + GY++E +G E W N+ L+
Sbjct: 8289 EAMTITWKPPLYDGGSKIMGYIIEKIAKGE------------------ERWKRCNEHLVP 8330
Query: 792 KTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIR 851
+T GL + RV+A NAAG SEP + P + I+ PK+ + L+ ++
Sbjct: 8331 ILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLE---VK 8387
Query: 852 RVGEAVNLVIPFQGKPRPELTWKKD-----GAEIDK------------------------ 882
R G+ + L G P P +TW KD EI K
Sbjct: 8388 R-GDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLT 8446
Query: 883 NQINIRNSET-DTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIE 941
+++I NS+ ++ + +R + R G Y ++V+ D + A + ++D PGPP E
Sbjct: 8447 QRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFE 8506
Query: 942 DVWGENVALTWTPPKDDGNAAITGYTIQKAD--KKSMEWFTVIEHYHRTSATITELVIGN 999
D+ +V W PP DDG + I YT++K D K EW V ++T+L+ G
Sbjct: 8507 DIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGK 8566
Query: 1000 EYYFRVFSENMCG 1012
EY FRV +EN G
Sbjct: 8567 EYLFRVRAENRFG 8579
Score = 210 bits (535), Expect = 5e-54
Identities = 177/671 (26%), Positives = 293/671 (43%), Gaps = 79/671 (11%)
Query: 380 EIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPL 439
+++ G K +RIR + GA A + + + A P +L P
Sbjct: 14032 DLVEGGKYEFRIRAKNTA------GAISAPSESTETIICKDEYEA-------PTIVLDPT 14078
Query: 440 TDQ--TVNLGKEICLKCE--ISENIP-GKWTKNGLPVQESDRLKVVHKGRIHKLVIANAL 494
T+ G I L + + +P W+K G ++ SD ++ L I A
Sbjct: 14079 IKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYAT 14138
Query: 495 TEDEGDY-VFAPDAYNVTLP-AKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGE 552
+D G+Y + A + + + KV V+D P G ++ ++ K L +
Sbjct: 14139 RKDAGEYTITATNPFGTKVEHVKVTVLDVP-----GPPGPVEISNVSAEKATL----TWT 14189
Query: 553 PPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLK----NE---- 604
PP + S I+E ++S L+ + D H+ K NE
Sbjct: 14190 PPLEDGGSPIKSYILEKR---------ETSRLLWTVVSEDIQSCRHVATKLIQGNEYIFR 14240
Query: 605 --------AGEAHASIKVKVVDF---PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILG 653
GE S VK+VD P PP P V+ V + ++W+ P DGGS I G
Sbjct: 14241 VSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITG 14300
Query: 654 YFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV 713
Y +ER++K+S RW+R + + + EG YE R+ A N GI PS S +
Sbjct: 14301 YHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVL 14360
Query: 714 PLAVTSPPTLLTVDSVTDTT---VTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDEN 770
PP + VTDTT ++ W P + G + GYV+E+ G A D
Sbjct: 14361 MKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGD-EAWIKDTT 14419
Query: 771 GEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILV 830
G A + T+F + L T K R+ A+N AG EP +V
Sbjct: 14420 GTA----------------LRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIV 14463
Query: 831 KEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNS 890
+ + P + L++T + R G ++ + +P +G+P PE+TW KD + KN+ NI N+
Sbjct: 14464 EREMAPD-FELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINL-KNRANIENT 14521
Query: 891 ETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVAL 950
E+ T++ I + R +GK+ + ++ ++ ++++++D PGP ++ D+ ++V L
Sbjct: 14522 ESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTL 14581
Query: 951 TWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENM 1010
W P DG + IT Y ++K + + T H+ + +T L G EY+FRV +EN
Sbjct: 14582 HWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENE 14641
Query: 1011 CGLSEDATMTK 1021
G+ E T+
Sbjct: 14642 YGIGEPTETTE 14652
Score = 207 bits (527), Expect = 5e-53
Identities = 119/408 (29%), Positives = 212/408 (51%), Gaps = 24/408 (5%)
Query: 620 PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTF 679
P PP P VT++ + + W P DGGS I GYF+E++ K+S W ++ + ++T
Sbjct: 20761 PGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQ 20820
Query: 680 EPKKMIEGVAYEVRIFAVNAIG---ISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTM 736
+ + E Y+ R+ AVNA G S+PS + P+ PP + + T +++T+
Sbjct: 20821 KVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITL 20880
Query: 737 RWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWI-VANKDLIDKTKF 795
W P + G + + GYV+E +Q +E E+W V+ K + T++
Sbjct: 20881 GWSKPVYDGGSAVTGYVVEI--------RQGEE----------EEWTTVSTKGEVRTTEY 20922
Query: 796 TITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGE 855
++ L + RV AVN AG EP ++P+ K+I+E P+I + L+ + I + GE
Sbjct: 20923 VVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGE 20982
Query: 856 AVNLVIPFQGKPRPELTWKKDGAEIDKN-QINIRNSETDTIIFIRKAERSHSGKYDLQVK 914
V ++IPF+G+P P +TW+KD + + + +I N+++ +++ I + R+ +GKY L ++
Sbjct: 20983 DVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIE 21042
Query: 915 VD-KFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADK 973
+++++ ++++D P Q ++++ V V L W PP DG + I Y I+K D
Sbjct: 21043 NGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDA 21102
Query: 974 KSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTK 1021
W V TS + +L ++FRV +EN G+ E T+
Sbjct: 21103 TKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTE 21150
Score = 206 bits (525), Expect = 8e-53
Identities = 160/599 (26%), Positives = 279/599 (46%), Gaps = 50/599 (8%)
Query: 444 VNLGKEICLKCEI-SENIPGK-WTKNGLPVQESD-RLKVVHKGRIHKLVIANALTEDEGD 500
V+ G+ L+ +I + IP W+K+G ++E+ R+++ + LV+ + + D G
Sbjct: 18414 VHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 18473
Query: 501 YVFAPDAYNVT--LPAKVHVIDPP-----KIILDGLDAD------NTVTVIAGNKLRLEI 547
Y+ T +P V V+D P + + G+ A+ N G + I
Sbjct: 18474 YILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYI 18533
Query: 548 PISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGE 607
I + W++ + + ++ T+ P + + +A Y I E+G
Sbjct: 18534 -IEKRETSRLSWTQVSTEVQALNYKV-TKLLPGNEYIFRVMAVNK----YGIGEPLESGP 18587
Query: 608 AHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWM 667
A K P PP P V+ + D ++ W P DGG+ I GY +E++ K+ RW
Sbjct: 18588 VTACNPYKP---PGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWT 18644
Query: 668 RLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVD 727
+ N + + EG +YE R+ A NA G+ +PS PS + PP +
Sbjct: 18645 KCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNP 18704
Query: 728 SVTDT---TVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIV 784
VTDT +V++ W P + G A + GYV+E EAA A++W
Sbjct: 18705 KVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEV--------------KEAA----ADEWTT 18746
Query: 785 ANKDL-IDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPR 843
+ +FT+T L + + R+ A+N+ G EP ++ +E IEPP+I +
Sbjct: 18747 CTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDA 18806
Query: 844 HLKQTYIRRVGEAVNLVIPFQGKPRPELTWKK-DGAEIDKNQINIRNSETDTIIFIRKAE 902
L++ + R + L + +G+P PE+ W+K +G D+ QI + +S T++ I
Sbjct: 18807 DLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSS--FTMLVIDNVT 18864
Query: 903 RSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAA 962
R SG+Y+L ++ + +TA ++++++D P P + I +V ++V L+W PP DG A
Sbjct: 18865 RFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAK 18924
Query: 963 ITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTK 1021
IT Y ++K + + T+ + +T+ I L G YYFRV + N G+ A T+
Sbjct: 18925 ITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTE 18983
Score = 206 bits (524), Expect = 1e-52
Identities = 159/616 (25%), Positives = 268/616 (43%), Gaps = 73/616 (11%)
Query: 434 KILTPLTDQTVNLGKEICLKCEISENIPG----------KWTKNGLPVQESDRLKVVHKG 483
K++ P + V L + + +K + P KWT +G ++ + V
Sbjct: 11199 KLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDN 11258
Query: 484 RIHKLVIANALTEDEGDYVFAPD--AYNVTLPAKVHVID---PPKIILDGLDADNTVTVI 538
L I N L D G+Y A + T+ + V+D PP ++ LD
Sbjct: 11259 FSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPE---- 11314
Query: 539 AGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIR-----TESYPDSSTLVIDIAERDD 593
+ IS +PP S I+E + S + L I ++
Sbjct: 11315 -------HMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGC 11367
Query: 594 SGVYHINLKNEAG-----EAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGG 648
V+ + +N+ G ++ ++ P PP P VT++ ++ ++W P DGG
Sbjct: 11368 EYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGG 11427
Query: 649 SPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMP 708
SPI GY++ER++ + +W+R+N + F + EG YE R+FA N G+SKPS
Sbjct: 11428 SPITGYYMERREV-TGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPS 11486
Query: 709 SRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAK 765
S P P+ PP + + T + W P G + + GYV+E C + T+
Sbjct: 11487 SDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVE-CQKPGTA-- 11543
Query: 766 QSDENGEAAYDLPAEDWIVANKD-LIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYY 824
W NKD LI + F + GL + R+KA N G EP+
Sbjct: 11544 ---------------QWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPREL 11588
Query: 825 SQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ 884
++ ++ K+I+ PP++ + + RVG+ + ++ +G+P P++TW K+G +
Sbjct: 11589 AESVIAKDILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEG------K 11642
Query: 885 INIRNSETDTI-------IFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQI 937
+ +R D I + I++A R+ GKY + K S + ++DRPGP Q
Sbjct: 11643 VLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQN 11702
Query: 938 VKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVI 997
+K+ +V EN ++W P D+G + IT + ++ W V + L+
Sbjct: 11703 LKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIVASDVTKRLIK-ANLLA 11761
Query: 998 GNEYYFRVFSENMCGL 1013
NEYYFRV +EN G+
Sbjct: 11762 NNEYYFRVCAENKVGV 11777
Score = 204 bits (520), Expect = 3e-52
Identities = 127/423 (30%), Positives = 206/423 (48%), Gaps = 36/423 (8%)
Query: 611 SIKVKVVD---FPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWM 667
S KV + D P PP P V +++W PP +GGSPI GY++E++++ S W
Sbjct: 9282 SDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWS 9341
Query: 668 RLNFDLC-----KETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTS 719
R++ K F +++EGV Y+ R A+NA GI PS PS P V P+
Sbjct: 9342 RVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPG 9401
Query: 720 PPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPA 779
PP+ V T +++++ W+PP G + + GY++E EG+T K+ +E +
Sbjct: 9402 PPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDK------- 9454
Query: 780 EDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKI 839
LI + + L K RVKAVN AG SEP + I +I E P++
Sbjct: 9455 ---------LITTCECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEV 9505
Query: 840 RIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWK---------KDGAEIDKNQINIRNS 890
I + + + G + + +G+P P+ +W+ KDG + +
Sbjct: 9506 FIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETA 9565
Query: 891 ETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVAL 950
E ++I I + +RSH+GKY + K +TA+ ++++D PGPP+ +K+ D+ + L
Sbjct: 9566 ENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRL 9625
Query: 951 TWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENM 1010
+W P DDG I GY I+K W V T+ + +L+ +Y+FRV +EN
Sbjct: 9626 SWKMPDDDGGDRIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENR 9685
Query: 1011 CGL 1013
G+
Sbjct: 9686 FGI 9688
Score = 204 bits (518), Expect = 5e-52
Identities = 146/522 (27%), Positives = 236/522 (45%), Gaps = 39/522 (7%)
Query: 520 DPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYP 579
+PP + LD + + ++AG LR+ ++G P P +W++ + + R+ ++
Sbjct: 8795 EPPAVELD-VSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGEL--DKDRVVIDNVG 8851
Query: 580 DSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMN 639
S L+I A R D G Y I N G A+ +V+V D P P + C++N
Sbjct: 8852 TKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLN 8911
Query: 640 WEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNA 699
W P DGGS I G+ IERK + W R + + + + ++EG Y+ R+ A N
Sbjct: 8912 WSDPEDDGGSEITGFIIERKDAKMHTW-RQPIE-TERSKCDITGLLEGQEYKFRVIAKNK 8969
Query: 700 IGISKPSM--PSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 757
G P P PL + P LT T +T+T+ W+ P G + + GY++E
Sbjct: 8970 FGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIE-- 9027
Query: 758 FEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAG 817
+ +D P D+ NK L T F + L RVKAVN G
Sbjct: 9028 --------------KRRHDKP--DFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIG 9071
Query: 818 ASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIR-RVGEAVNLVIPFQGKPRPELTWKKD 876
SEP +++++ PP I++ ++ I+ + GE V++ G P P++ W K+
Sbjct: 9072 ESEPS-LPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKN 9130
Query: 877 GAEIDK-------NQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQII 929
I+K + + SE T + I KA R G Y + ++ +++
Sbjct: 9131 ETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVY 9190
Query: 930 DRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKAD--KKSMEWFTVIEHYHR 987
DRP PP+ + + D+ E+ LTW P D+G + IT Y I K D +K EW V
Sbjct: 9191 DRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVE 9250
Query: 988 TSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARD 1029
I +L+ +Y FRV + N G+S++ K V+ +D
Sbjct: 9251 KRYGIWKLIPNGQYEFRVRAVNKYGISDEC---KSDKVVIQD 9289
Score = 203 bits (516), Expect = 9e-52
Identities = 164/613 (26%), Positives = 270/613 (44%), Gaps = 62/613 (10%)
Query: 443 TVNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGD 500
T+ G ++ L + K WTK + +++ + + G+ VI D G
Sbjct: 22753 TIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGK 22812
Query: 501 YVFAPDAYNVT--LPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPP---- 554
Y + T + V V+D P G TV+ + K L + E
Sbjct: 22813 YTLTVKNASGTKAVSVMVKVLDSP-----GPCGKLTVSRVTQEKCTLAWSLPQEDGGAEI 22867
Query: 555 -----PKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG--- 606
+ SR + I+EG T SY V+ +++ ++ + N+ G
Sbjct: 22868 THYIVERRETSRLNWVIVEGE--CPTLSY------VVTRLIKNNEYIFRVRAVNKYGPGV 22919
Query: 607 --EAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSS 664
E+ + P PP P G + I+ W P DGG+ I Y +++++K+S
Sbjct: 22920 PVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSL 22979
Query: 665 RWMRLNFD-LCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV----PLAVTS 719
RW R+N D + +T + ++EG Y+ R+ AVNA G S+PS S F+ P
Sbjct: 22980 RWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASN-FISCREPSYTPG 23038
Query: 720 PPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPA 779
PP+ V T ++++ W P + G + GYVLE K +D+
Sbjct: 23039 PPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEM------QEKDTDQ---------- 23082
Query: 780 EDWI-VANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPK 838
W V I T+FT+ L K RV AVN G SE I E IE P
Sbjct: 23083 --WYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPD 23140
Query: 839 IRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFI 898
+ + LK+T R G ++ L++ G+P P +TW K G ++ I I +E+ +++ +
Sbjct: 23141 LELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAI-IDTTESYSLLIV 23199
Query: 899 RKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDD 958
K R +GKY ++ + ++A++ +++ D PGP VK+++V ++V +TW P D
Sbjct: 23200 DKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTID 23259
Query: 959 GNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE--- 1015
G A + Y ++K + + TV +T I+ LV G YYFRV EN+ G+ E
Sbjct: 23260 GGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCE 23319
Query: 1016 --DATMTKESAVI 1026
DA + E ++
Sbjct: 23320 TSDAVLVSEVPLV 23332
Score = 201 bits (512), Expect = 3e-51
Identities = 157/613 (25%), Positives = 280/613 (45%), Gaps = 46/613 (7%)
Query: 420 GQSSAKLSVDLKPLKILTPLTDQ-TVNLGKEICLKCEI-SENIPG-KWTKNGLPVQESDR 476
G +AK V+L + + D VN G+ L+ ++ + +P +W + ++ES R
Sbjct: 17307 GPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESAR 17366
Query: 477 LKVVHKGRIHKLVIANALTEDEGDYVFAPD--AYNVTLPAKVHVIDPPKIILDGLDADNT 534
++ + L++ +A+ D G Y+ A + + P V V+D P +
Sbjct: 17367 CEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRP----GPPEGPVQ 17422
Query: 535 VTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIR-----TESYPDSSTLVIDIA 589
VT + K L + PP + S ++E R S +++L +
Sbjct: 17423 VTGVTSEKCSL----TWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKL 17478
Query: 590 ERDDSGVYHINLKNE--AGEAHASIKVKVVD---FPDPPVAPTVTEVGDDWCIMNWEPPA 644
+ V+ I N+ GE S V + + P PP + VT + D + W P
Sbjct: 17479 LEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPD 17538
Query: 645 YDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISK 704
DGGS I+GY +E++ + RW++ N + + E YE R+ A NA G+ +
Sbjct: 17539 SDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGE 17598
Query: 705 PSMPS---RPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGS 761
PS + + P+ PPT + T ++T+ W P + G + + GYV+E C
Sbjct: 17599 PSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEIC---- 17654
Query: 762 TSAKQSDENGEAAYDLPAEDW-IVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASE 820
++DE E+W IV + + T+F I+ L + +RV A+N G E
Sbjct: 17655 ----KADE----------EEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGE 17700
Query: 821 PKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI 880
+ ++ +E P++ + L++ + R G + + IPF+G+P PE+TW ++ E
Sbjct: 17701 ATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEF 17760
Query: 881 DKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKI 940
+++ I T + I +R+ +GKY L+++ ++A + ++++D PGPPQ + +
Sbjct: 17761 T-DKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAV 17819
Query: 941 EDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNE 1000
++V ++ L W PP DG A + Y I K + + V +TS + L G
Sbjct: 17820 KEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAI 17879
Query: 1001 YYFRVFSENMCGL 1013
YYFRV +EN G+
Sbjct: 17880 YYFRVMAENEFGV 17892
Score = 201 bits (510), Expect = 4e-51
Identities = 139/497 (27%), Positives = 230/497 (46%), Gaps = 32/497 (6%)
Query: 620 PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTF 679
P P P V V + + WE P +DGGS I+GY++E+K++ + W++ N C E +
Sbjct: 22536 PSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNY 22595
Query: 680 EPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWR 739
+ ++EG+ Y+ R +A+NA G+SK S SRP + P V VT +TV++ W
Sbjct: 22596 KVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAPGRPEVTDVTRSTVSLIWS 22655
Query: 740 PPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITG 799
P + G + + GY++E K E G+ W+ N ++ FT+T
Sbjct: 22656 APAYDGGSKVVGYIIE--------RKPVSEVGDGR-------WLKCNYTIVSDNFFTVTA 22700
Query: 800 LPTDAKIFVRVKAVNAAGA-SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIR-RVGEAV 857
L RV A NAAG S+ + P+ ++ PPK + L + R G +
Sbjct: 22701 LSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDL 22760
Query: 858 NLVIPFQGKPRPELTWKKDGAEIDK-NQINIRNSETDTIIFIRKAERSHSGKYDLQVKVD 916
L GKP P++ W K E+D +++++ + I+ +RS SGKY L VK
Sbjct: 22761 VLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNA 22820
Query: 917 KFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSM 976
+ S+ ++++D PGP + + V E L W+ P++DG A IT Y +++ + +
Sbjct: 22821 SGTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRL 22880
Query: 977 EWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNP 1036
W V S +T L+ NEY FRV + N G + ++AR+ +P
Sbjct: 22881 NWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYG---PGVPVESEPIVARNSFTIPSP 22937
Query: 1037 --VYEDFDFSEAPM---FTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMK-NKVAIVDD 1090
+ E+ + + +T+P + G N N V K + W + NK +V D
Sbjct: 22938 PGIPEEVGTGKEHIIIQWTKPESD-----GGNEISNYLVDKREKKSLRWTRVNKDYVVYD 22992
Query: 1091 PRYRMFSNQGVCTLEIR 1107
R ++ S C + R
Sbjct: 22993 TRLKVTSLMEGCDYQFR 23009
Score = 196 bits (497), Expect = 1e-49
Identities = 219/924 (23%), Positives = 366/924 (39%), Gaps = 131/924 (14%)
Query: 263 QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 322
+V + V F E+ + KW++N + I S+KYI K L I + + D + Y
Sbjct: 6345 RVKEQQEVVFNCEVNTEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANY 6404
Query: 323 YVTAGDE-----KCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKN 377
V+ + K + L V E + + + L+D + V C+V+ + +KW KN
Sbjct: 6405 NVSLTNHRGENVKSAANLIVEEEDLRIVEPLKDIETMEKKSVTFWCKVNRLNVTLKWTKN 6464
Query: 378 GEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILT 437
GEE+ + YR V+ KH+L I+ D EY V +S A+L + P + +
Sbjct: 6465 GEEVPFDNRVSYR--VDKYKHMLTIKDCGFPDEGEYIVTAGQDKSVAELLIIEAPTEFVE 6522
Query: 438 PLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTE 496
L DQTV + C++S E KW +NG ++E + K G IH+L+I + +
Sbjct: 6523 HLEDQTVTEFDDAVFSCQLSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLD 6582
Query: 497 DEGDYVFAPD-----AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISG 551
DE +Y + A V +I PP+ IL+ AD V + NK ++E+
Sbjct: 6583 DECEYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGAD-VVFLAELNKDKVEV---- 6637
Query: 552 EPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHAS 611
W R + +++G + DI RD G Y K++ EA A
Sbjct: 6638 ------QWLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQ-GEYRFIAKDK--EARAK 6688
Query: 612 IKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYF-IERKKKQSSRWMRLN 670
+++ AP + D + D G P+ + K + W + N
Sbjct: 6689 LELAA--------APKIKTADQDLVV--------DVGKPLTMVVPYDAYPKAEAEWFKEN 6732
Query: 671 FDL--------CKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPT 722
L ++T+F + +G +I N G ++ + + + V P
Sbjct: 6733 EPLSTKTIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKV---IDVPGPVR 6789
Query: 723 LLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDW 782
L V D V++ W P G + + GYV+E D+ + W
Sbjct: 6790 NLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVE------------------RRDIKRKTW 6831
Query: 783 IVANKDLIDKTKFTITGLPTDAKIFV-RVKAVNAAGASEPKYYSQPILVKEIIEPPKIRI 841
++A D + +FT+TGL ++ RV A N G EP P+ + + P
Sbjct: 6832 VLAT-DRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVP---- 6886
Query: 842 PRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKD----GAEIDKNQINIRNSET---DT 894
G +N+ I + LTW+ GAEI I +R+ + DT
Sbjct: 6887 ------------GPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDT 6934
Query: 895 IIFIRKAERS-------HSGKYDLQVKVDKFV-----ETASIDIQI---IDRPGPPQIVK 939
+ +R + S +Y +V+ + A+ +++ I+RP PP +
Sbjct: 6935 AMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLT 6994
Query: 940 IEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV-IEHYHRTSATITELVIG 998
D +V L W PP DG + I GY I++ ++ W ++ + +T L G
Sbjct: 6995 SSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKG 7054
Query: 999 NEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYA 1058
N+Y +RV +EN G+S+ + + P+ D F E M +
Sbjct: 7055 NKYLYRVSAENKAGVSDPSEIL--------------GPLTADDAFVEPTMDLSAFKDGLE 7100
Query: 1059 IAGYNA-TLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTY 1117
+ N T+ G P+P TW + R +M + L I D G Y
Sbjct: 7101 VIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIY 7160
Query: 1118 CCKAVNDLGTVEIECKLEVKVIAQ 1141
K N + T+ E ++V VIA+
Sbjct: 7161 TLKLENRVKTISGE--IDVNVIAR 7182
Score = 195 bits (496), Expect = 2e-49
Identities = 141/519 (27%), Positives = 228/519 (43%), Gaps = 38/519 (7%)
Query: 518 VIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTES 577
++ PP++ LD + + +TV G +R+ + G P P W++ K ++ R +
Sbjct: 11597 ILHPPEVELD-VTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREK---RVDL 11652
Query: 578 YPDSSTLVIDIAE--RDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDW 635
D + + I E R D G Y I+ KN +G A S V V+D P P VT V +
Sbjct: 11653 IQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKEN 11712
Query: 636 CIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIF 695
C ++WE P +GGS I + +E +K W + D+ K ++ Y R+
Sbjct: 11713 CTISWENPLDNGGSEITNFIVEYRKPNQKGWSIVASDVTKRLI--KANLLANNEYYFRVC 11770
Query: 696 AVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGY 752
A N +G+ P + P+ P L + T V ++WR PD+ G + Y
Sbjct: 11771 AENKVGVGPTIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSY 11830
Query: 753 VLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKA 812
+E +GS +DW +K I +T + + + RV+
Sbjct: 11831 HVERRLKGS------------------DDWERVHKGSIKETHYMVDRCVENQIYEFRVQT 11872
Query: 813 VNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELT 872
N G S+ ++ ++VKE ++ P + + L + G+ + L +GKP PE+
Sbjct: 11873 KNEGGESD-WVKTEEVVVKEDLQKPVLDLK--LSGVLTVKAGDTIRLEAGVRGKPFPEVA 11929
Query: 873 WKKDGAEIDKNQ---INIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQII 929
W KD D + + I + + KA+RS GKY + A + ++
Sbjct: 11930 WTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVL 11989
Query: 930 DRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTS 989
D+PGP + +KI DV + + W PP+DDG I Y ++K + K M W T
Sbjct: 11990 DKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPG 12049
Query: 990 ATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIAR 1028
T+T L+ GNEY FRV +EN G T+ VIA+
Sbjct: 12050 TTVTRLIEGNEYIFRVRAENKIGTGPP---TESKPVIAK 12085
Score = 195 bits (495), Expect = 2e-49
Identities = 123/422 (29%), Positives = 206/422 (48%), Gaps = 28/422 (6%)
Query: 620 PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTF 679
P PP A V +V + WEPP DGG PI Y IE+K++ +RW++ + F
Sbjct: 7879 PGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNF 7938
Query: 680 EPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTM 736
+IEG + ++ A N G+ PS P+ P + SPP L V + +
Sbjct: 7939 RVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAI 7998
Query: 737 RWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFT 796
W+PP+ G + + GY +E C G+ E W+ N I KF
Sbjct: 7999 AWKPPEKNGGSPIIGYHVEMCPVGT------------------EKWMRVNSRPIKDLKFK 8040
Query: 797 IT-GLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGE 855
+ G+ D + +RV+AVNA G SEP S+ ++ K+ P I + H I GE
Sbjct: 8041 VEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETH---DIIVIEGE 8097
Query: 856 AVNLVIPFQGKPRPELTWKKDGAEID-KNQINIRNSETDTIIFIRKAERSHSGKYDLQVK 914
+++ +PF+ P P ++W KDG E+ +++ ++N + + K+ R+ +G Y + ++
Sbjct: 8098 KLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLE 8157
Query: 915 VDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKK 974
TASI++++I PGP + +K D+ + LTW PP+ DG I Y +++ +
Sbjct: 8158 NKLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAG 8217
Query: 975 SMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYK 1034
+ V+ ++ S T+ +L+ EY+FRV + N G E + ++ VIA+D K
Sbjct: 8218 RRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIEL--KNPVIAQDPKQPP 8275
Query: 1035 NP 1036
+P
Sbjct: 8276 DP 8277
Score = 194 bits (493), Expect = 4e-49
Identities = 148/575 (25%), Positives = 258/575 (44%), Gaps = 49/575 (8%)
Query: 464 WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAK----VHVI 519
W K+G+ +++ +++ L + +A + G V+ +A N + AK V V
Sbjct: 21687 WFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRG--VYTVEAKNASGSAKAEIKVKVQ 21744
Query: 520 DPPKIILDGLDADNTVTVIAGNKLRL--EIPISGEPPP-------KAMWSRGDKAIMEGS 570
D P ++ + N I G K+ L + P++ P K SR A++E
Sbjct: 21745 DTPGKVVGPIRFTN----ITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIED- 21799
Query: 571 GRIRTESYPDSSTLVIDIAERDDSGV--YHINLKNEAGEAHASIKVKVVDFPDPPVAPTV 628
+ +SY + + + S V + + ++ A I+ V PD P P
Sbjct: 21800 -KCEAQSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTV---PDAPGIPEP 21855
Query: 629 TEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMR-LNFDLCKETTFEPKKMIEG 687
+ + + + W P DGGS I Y +ER++K+S+RW++ ++ ET F+ + EG
Sbjct: 21856 SNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEG 21915
Query: 688 VAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHI 744
YE + A NA G+ S SR P+ PPT++ V + TTV++ W P
Sbjct: 21916 NEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFD 21975
Query: 745 GAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDA 804
G + GY++E C DW N + KT++T+T L
Sbjct: 21976 GGMEIIGYIIEMC------------------KADLGDWHKVNAEACVKTRYTVTDLQAGE 22017
Query: 805 KIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQ 864
+ RV A+N AG + + I + + P++ I + KQT++ R G ++ L I +Q
Sbjct: 22018 EYKFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQ 22077
Query: 865 GKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASI 924
G+P P W K + + + +I +++ + + + R+ +GKY L V+ + ++ +
Sbjct: 22078 GRPTPTAVWSKPDSNLSL-RADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITF 22136
Query: 925 DIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEH 984
++++D PGPP + +DV + L W P DG A I Y ++K + W + E
Sbjct: 22137 TVKVLDTPGPPGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEK 22196
Query: 985 YHRTSATITELVIGNEYYFRVFSENMCGLSEDATM 1019
R + +L G YYFRV + N G+ E M
Sbjct: 22197 CTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEM 22231
Score = 185 bits (470), Expect = 2e-46
Identities = 172/692 (24%), Positives = 288/692 (41%), Gaps = 92/692 (13%)
Query: 373 KWFKNGEEIIP-----------GPKSRYRIRVEGKKHILIIEGATKA-------DAAEYS 414
+W + E ++P G + ++R+R E I AT DA +
Sbjct: 8320 RWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVI 8379
Query: 415 VMTT-----GGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKC---------EISENI 460
+ T+ G + + S+ P +T + D+ V + +EI + E+ E
Sbjct: 8380 LRTSLEVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEE 8439
Query: 461 PGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYN--VTLPAKVHV 518
P LP+ + + KG +L + ++L D G Y+ + + P V V
Sbjct: 8440 PFV-----LPLTQRLSIDNSKKGE-SQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSV 8493
Query: 519 IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESY 578
+D P ++ + D T + EPP G I+ + + ++
Sbjct: 8494 LDTPGPPINFVFEDIRKTSVL---------CKWEPP----LDDGGSEIINYTLEKKDKTK 8540
Query: 579 PDSSTLVIDIAERD-----------DSGVYHINLKNEAGEAHASIKVKVVDF-----PDP 622
PDS +V+ R ++ + +N G + +V PD
Sbjct: 8541 PDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPFGPPDA 8600
Query: 623 PVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPK 682
P P V +V + ++ W P D GSPILGY++E+++ S+ W R+N L
Sbjct: 8601 PDKPIVEDVTSNSMLVKWNEPK-DNGSPILGYWLEKREVNSTHWSRVNKSLLNALKANVD 8659
Query: 683 KMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSP--PTLLTVDSVTDTTVTMRWRP 740
++EG+ Y R+ A NA G K S PS P SP P + V + TT+ + W P
Sbjct: 8660 GLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIELEWEP 8719
Query: 741 PDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGL 800
P G + GY ++ G+ +W + +I ++T+ +
Sbjct: 8720 PAFNGGGEIVGYFVDKQLVGT------------------NEWSRCTEKMIKVRQYTVKEI 8761
Query: 801 PTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLV 860
A +RV AVNAAG P +QP+ V E EPP + + +K G+ + +
Sbjct: 8762 REGADYKLRVSAVNAAGEGPPG-ETQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIP 8820
Query: 861 IPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVE 920
G+P P W K+ E+DK+++ I N T + + I+ A R G+Y + +
Sbjct: 8821 AVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSK 8880
Query: 921 TASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFT 980
A+ +++ D PGP +K + L W+ P+DDG + ITG+ I++ D K W
Sbjct: 8881 FAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQ 8940
Query: 981 VIEHYHRTSATITELVIGNEYYFRVFSENMCG 1012
IE R+ IT L+ G EY FRV ++N G
Sbjct: 8941 PIE-TERSKCDITGLLEGQEYKFRVIAKNKFG 8971
Score = 184 bits (467), Expect = 4e-46
Identities = 177/720 (24%), Positives = 313/720 (43%), Gaps = 79/720 (10%)
Query: 344 VTKQLEDTTAYCGERVELECE-VSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILII 402
+ K+++D T GE +L C+ V ++KW++ G+E+I K Y++ +G+ H L +
Sbjct: 24230 IRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRK--YKMSSDGRTHTLTV 24287
Query: 403 EGATKADAAEYSVMTTGG----QSSAKLSVDLKP-LKILTPLTDQTVN-LGKEICLKCE- 455
+ D Y+ + T ++S+KL + P PL ++ +G + L
Sbjct: 24288 MTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMY 24347
Query: 456 ISENIPGK-WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPA 514
I +P W +Q S+ + + + LV+ N + Y V L
Sbjct: 24348 IGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAG------KYKVQLSN 24401
Query: 515 KVHVIDPPKIILDGLDADN----TVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIME-- 568
+D ILD D T ++ L+ IS +PP S ++E
Sbjct: 24402 VFGTVDA---ILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKC 24458
Query: 569 -----GSGRIRTESYPDSSTLVIDIAERDDSGVY-HINLKNEAG-----EAHASIKVKV- 616
++ + + ++ ++++ E ++G Y ++ +N G E + + +K
Sbjct: 24459 EAKEGAEWQLVSSAISVTTCRIVNLTE--NAGYYFRVSAQNTFGISDPLEVSSVVIIKSP 24516
Query: 617 VDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKE 676
+ P P PT+T V D C++ W+PPA DGG+ I Y++E+++K+ ++W+ + + +E
Sbjct: 24517 FEKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRE 24576
Query: 677 TTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTM 736
T F K +IEG+ YE R+ N G S+ S S P P + + + + V
Sbjct: 24577 TVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRY 24636
Query: 737 RWRPPDHIGAAGLDGYVLEYCFEG----STSAKQSDENGEAAYDLPAEDWIVANKDLIDK 792
+ G ++++ +G + K + + Y
Sbjct: 24637 QSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYH---------------- 24680
Query: 793 TKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRR 852
+ I + D +V+A N G+ E+ P KI +P+ L+
Sbjct: 24681 -QLIIASVTDDDATVYQVRATNQGGSVSGT------ASLEVEVPAKIHLPKTLEGMGAVH 24733
Query: 853 V--GEAVNLVIPFQGKPRPELTWKKDGAEIDKN---QINIRNSETDTIIFIRKAERSHSG 907
GE V++ IPF GKP P +TW+K ID N Q+ + S T +++F ER +G
Sbjct: 24734 ALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFT-SLVFPNGVERKDAG 24792
Query: 908 KYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYT 967
Y + K ++ ++++ + D P PP+ VK+ DV ++V LTWT P DG + IT Y
Sbjct: 24793 FYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYI 24852
Query: 968 IQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE-----DATMTKE 1022
++K + W V T T+ L Y FRV +EN GLS+ + T+TKE
Sbjct: 24853 VEKCATTAERWLRV-GQARETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKE 24911
Score = 169 bits (427), Expect = 2e-41
Identities = 165/704 (23%), Positives = 284/704 (40%), Gaps = 93/704 (13%)
Query: 350 DTTAYCGERV-ELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKA 408
D CGE V E + EV+ + KW+ YR++ + +GA+K
Sbjct: 7327 DKWVACGEPVAETKMEVTGLEEG-KWYA------------YRVKALNR------QGASKP 7367
Query: 409 DAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGK--WTK 466
+ Q + ++ +D+K L LT V G +I L ++ K WTK
Sbjct: 7368 SRPTEEIQAVDTQEAPEIFLDVKLLAGLT------VKAGTKIELPATVTGKPEPKITWTK 7421
Query: 467 NGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNV----TLPAKVHVIDP- 521
+ +++ R+ + + + + I ++ D G Y+ +A NV T +V+V+D
Sbjct: 7422 ADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYII--EAVNVCGRATAVVEVNVLDKP 7479
Query: 522 -PKIILDGLDADNTVTVIAGNKLR-------LEIPISGEPPPKAMWSRGDKAIMEGSGRI 573
P D D N ++ N R + +W + + + + +
Sbjct: 7480 GPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFK- 7538
Query: 574 RTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGD 633
T+ P+ + AE +Y + +A A + D P PP +++
Sbjct: 7539 ATKLIPNKEYIFRVAAE----NMYGVGEPVQASPITAKYQ---FDPPGPPTRLEPSDITK 7591
Query: 634 DWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVR 693
D + W P DGGSPI GY++ER + +W+R N K+TT+ K + Y R
Sbjct: 7592 DAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFR 7651
Query: 694 IFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLD 750
+ A N G KPS + P + P+ PP TV V T+V + W P+H G A ++
Sbjct: 7652 VLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIE 7711
Query: 751 GYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRV 810
YV+E G+ ++W+ + + T+ + GL + RV
Sbjct: 7712 SYVIEMLKTGT------------------DEWVRVAEG-VPTTQHLLPGLMEGQEYSFRV 7752
Query: 811 KAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRP- 869
+AVN AG SEP S P+L +E + PP PR L+ I + + +P + P
Sbjct: 7753 RAVNKAGESEPSEPSDPVLCREKLYPPS--PPRWLEVINITKNTADLKWTVPEKDGGSPI 7810
Query: 870 -----------ELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKF 918
W+ + + + ++ R A + G+ D
Sbjct: 7811 TNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTE----- 7865
Query: 919 VETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEW 978
+E + + PGPP + + DV +V L W PPK+DG I Y I+K ++ W
Sbjct: 7866 IEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRW 7925
Query: 979 FTVIEHY-HRTSATITELVIGNEYYFRVFSENMCGLSEDATMTK 1021
+ + +T+++ G E F+V +EN G+ + T+
Sbjct: 7926 VKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTE 7969
Score = 162 bits (411), Expect = 1e-39
Identities = 110/364 (30%), Positives = 175/364 (48%), Gaps = 16/364 (4%)
Query: 264 VDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYY 323
V G F EL+ + V+WY G+++ PS K + +G L + + ++ D E
Sbjct: 5902 VTAGETATFDCELSYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQ 5961
Query: 324 VTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIP 383
+TA D K LFV+EPP+ TK LED T G LECEVS ++A VKWFKNG EI+
Sbjct: 5962 LTAKDFKTHANLFVKEPPVEFTKPLEDQTVEEGATAVLECEVSRENAKVKWFKNGTEILK 6021
Query: 384 GPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQT 443
K Y I +G+ L+I T D Y+ ++S L+V ++ L PLTD
Sbjct: 6022 SKK--YEIVADGRVRKLVIHDCTPEDIKTYTCDAKDFKTSCNLNVVPPHVEFLRPLTDLQ 6079
Query: 444 VNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV 502
V + +CE+S EN KW K+G +++ + ++ KG + LVI L +DE +Y
Sbjct: 6080 VREKEMARFECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEY- 6138
Query: 503 FAPDAYNVTLPAKVHVIDPPKII---LDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMW 559
+ + + V++ + L ++ T T+ KL E+ +P + +W
Sbjct: 6139 -SCEVRTARTSGMLTVLEEEAVFTKNLANIEVSETDTI----KLVCEV---SKPGAEVIW 6190
Query: 560 SRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDF 619
+GD+ I+E +GR + LVI A +D+G Y+ L + + + +F
Sbjct: 6191 YKGDEEIIE-TGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEF 6249
Query: 620 PDPP 623
P
Sbjct: 6250 ISKP 6253
Score = 152 bits (383), Expect = 2e-36
Identities = 107/326 (32%), Positives = 162/326 (49%), Gaps = 37/326 (11%)
Query: 519 IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESY 578
+DPP+I +D D T+ V AG +++ I G+P P W +GD+ + + R+ +S
Sbjct: 16233 VDPPRISMDPKYKD-TIVVHAGESFKVDADIYGKPIPTIQWIKGDQEL-SNTARLEIKST 16290
Query: 579 PDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTV-TEVGDDWCI 637
+++L + A R DSG Y + KN AGE ++ VKV+D P PP P V + V + C
Sbjct: 16291 DFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCT 16350
Query: 638 MNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDL----CKETTFEPKKMIEGVAYEVR 693
+ W+PP DGGS I+ Y +ER++ W ++ ++ CK T K++EG Y R
Sbjct: 16351 LAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVT-----KLLEGNEYTFR 16405
Query: 694 IFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLD 750
I AVN G+ +P + S P V P V P V +VT ++ + W P G + +
Sbjct: 16406 IMAVNKYGVGEP-LESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEIL 16464
Query: 751 GYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRV 810
GYVLE + D+ G W +K LI + + +TGL + RV
Sbjct: 16465 GYVLE----------KRDKEGIR--------WTRCHKRLIGELRLRVTGLIENHDYEFRV 16506
Query: 811 KAVNAAGASEPKYYSQPILVKEIIEP 836
A NAAG SEP S P ++ +P
Sbjct: 16507 SAENAAGLSEP---SPPSAYQKACDP 16529
Score = 150 bits (379), Expect = 7e-36
Identities = 100/328 (30%), Positives = 160/328 (48%), Gaps = 26/328 (7%)
Query: 522 PKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS 581
P++ L G+ V AG+ +++EIP+ G P P W +GD+ I++ + R+ E+ S
Sbjct: 14758 PELDLRGI-YQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQ-ILKQTQRVNFETTATS 14815
Query: 582 STLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT-VTEVGDDWCIMNW 640
+ L I+ R DSG Y + +N GE I ++V D P PP P EV D+ +W
Sbjct: 14816 TILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSW 14875
Query: 641 EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAI 700
+PP DGG PI Y +E ++ S+ W+ L + + TT++ ++ G+ Y+ R+ A N
Sbjct: 14876 DPPENDGGVPISNYVVEMRQTDSTTWVELATTVIR-TTYKATRLTTGLEYQFRVKAQNRY 14934
Query: 701 GISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 757
G+ P + S V P V PP V +VT ++T+ W P G + + GY +E
Sbjct: 14935 GVG-PGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVE-- 14991
Query: 758 FEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAG 817
+ + NG W +K L+ F +GL RV A N AG
Sbjct: 14992 --------RKERNGIL--------WQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAG 15035
Query: 818 ASEPKYYSQPILVKEIIEPPKIRIPRHL 845
S+P S+P+L + I+PP +P ++
Sbjct: 15036 KSKPSKPSEPMLALDPIDPPGKPVPLNI 15063
Score = 150 bits (379), Expect = 7e-36
Identities = 103/337 (30%), Positives = 165/337 (48%), Gaps = 25/337 (7%)
Query: 506 DAYNVTLPAKV-HVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDK 564
D + LP + ++PP+I + + +TV V AG+ L+++IPISG+P PK SR D
Sbjct: 20152 DPRELLLPVLIKEQLEPPEIDMKNFPS-HTVYVRAGSNLKVDIPISGKPLPKVTLSR-DG 20209
Query: 565 AIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPV 624
++ + R TE ++ T+ + + D+G Y I N +G A I + V+D P PP
Sbjct: 20210 VPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPT 20269
Query: 625 APTV-TEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKK 683
P V +++ ++ + WEPP YDGGS + Y + +++ ++ W ++ + + T + K
Sbjct: 20270 GPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVAR-TMMKVMK 20328
Query: 684 MIEGVAYEVRIFAVNAIGISK--PSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPP 741
+ G Y+ RI A N GIS S +P PP+ V +VT ++T+ W P
Sbjct: 20329 LTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEP 20388
Query: 742 DHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLP 801
G + + GY LE D N W ANK +I T F +T +
Sbjct: 20389 VSNGGSAVVGYHLE----------MKDRNSIL--------WQKANKLVIRTTHFKVTTIS 20430
Query: 802 TDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPK 838
RV A NAAG +P + S+P+L + EPP+
Sbjct: 20431 AGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACEPPR 20467
Score = 149 bits (377), Expect = 1e-35
Identities = 148/568 (26%), Positives = 234/568 (41%), Gaps = 60/568 (10%)
Query: 360 ELEC-EVSEDDANVKWFK----NGEEII-----------PGPKSRYRIRVEGKKHILIIE 403
ELE +S+D ++W K G+EI+ K + R++ K+ I
Sbjct: 24131 ELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQ--FTIG 24188
Query: 404 GATKADAAEYSVMT---TGGQSSAKLSVDLKPLK-------ILTPLTDQTVNLGKEICLK 453
G +A E+ V TG + ++ +K I + D T LG+ L
Sbjct: 24189 GLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLS 24248
Query: 454 CEI-SENIPG-KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY--VFAPDAYN 509
C+I +P KW + G + +S + K+ GR H L + EDEG Y + +
Sbjct: 24249 CQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGE 24308
Query: 510 VTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEG 569
V +K+ + P+ G G+ LRL + G P P W G K +++
Sbjct: 24309 VETSSKLLLQATPQFH-PGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQK-LLQN 24366
Query: 570 SGRIRTESYPDSSTLVI-DIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTV 628
S I E+ + LV+ ++ + +G Y + L N G A + V++ D PD P P V
Sbjct: 24367 SENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIV 24426
Query: 629 TE-VGDDWCIMNWEPPAYDGGSPILGYFIER-KKKQSSRWMRLNFDLCKETTFEPKKMIE 686
E + + +++W+PPA DGGS I Y +E+ + K+ + W +L TT + E
Sbjct: 24427 IEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEW-QLVSSAISVTTCRIVNLTE 24485
Query: 687 GVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDH 743
Y R+ A N GIS P S + P P T+ +VT + + W+PP
Sbjct: 24486 NAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAWKPPAS 24545
Query: 744 IGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTD 803
G A + Y LE ++ +N WI + I +T F++ L
Sbjct: 24546 DGGAKIRNYYLE--------KREKKQN----------KWISVTTEEIRETVFSVKNLIEG 24587
Query: 804 AKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPF 863
+ RVK N G SE S+PI K + L+ +R A LV
Sbjct: 24588 LEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNA-TLVCKV 24646
Query: 864 QGKPRPELTWKKDGAEIDKNQINIRNSE 891
G P+P + W + G EI + + R E
Sbjct: 24647 TGHPKPIVKWYRQGKEIIADGLKYRIQE 24674
Score = 148 bits (373), Expect = 3e-35
Identities = 104/358 (29%), Positives = 163/358 (45%), Gaps = 33/358 (9%)
Query: 491 ANALTEDEGDYVFAPDAYNVT---LPAKVHVIDPPKIILDGLDA----DNTVTVIAGNKL 543
A LTE + +Y F A N P+++ V+ ++ LD D +
Sbjct: 13637 AKDLTEGK-EYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNF 13695
Query: 544 RLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKN 603
RL+IPI G+P P W +G+ + + R+ ES ++TL++ ++ D+G Y I LKN
Sbjct: 13696 RLKIPIKGKPAPSVSWKKGEDPLATDT-RVSVESSAVNTTLIVYDCQKSDAGKYTITLKN 13754
Query: 604 EAGEAHASIKVKVVDFPDPPVAPT-VTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQ 662
AG +I +KVV P P P EV + + W PP DGGS I Y +E++
Sbjct: 13755 VAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSV 13814
Query: 663 SSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTS 719
+++W+ ++TTF ++ EG+ Y R+ A N G+ + + S P V P V
Sbjct: 13815 NNKWVTCA-SAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGE-GLKSEPIVARHPFDVPD 13872
Query: 720 PPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPA 779
P + V +V++ W P G + + GY LE+ S
Sbjct: 13873 APPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLL---------------- 13916
Query: 780 EDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPP 837
W ANK I F +TGL + RV A+N AG +P S+P++ + I+PP
Sbjct: 13917 --WKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPP 13972
Score = 145 bits (365), Expect = 3e-34
Identities = 110/374 (29%), Positives = 173/374 (46%), Gaps = 19/374 (5%)
Query: 263 QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 322
QV + RF EL+ +VKW+K+G EI+ KY KG RIL IN C + D++EY
Sbjct: 6079 QVREKEMARFECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEY 6138
Query: 323 YVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEII 382
+ S L V E + TK L + + ++L CEVS+ A V W+K EEII
Sbjct: 6139 SCEVRTARTSGMLTVLEEEAVFTKNLANIEVSETDTIKLVCEVSKPGAEVIWYKGDEEII 6198
Query: 383 PGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQ 442
RY I EG+K IL+I+ A DA Y+ ++ K+ V + ++ +
Sbjct: 6199 --ETGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNL 6256
Query: 443 TVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 501
+ G++ C IS E+ P +W ++ ++ D+ V+ G+ LV+ +A +D G Y
Sbjct: 6257 EILEGEKAEFVCSISKESFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTY 6316
Query: 502 VF----APDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKA 557
V A A ++T+ K+ ++ P K D V E+ G KA
Sbjct: 6317 VVMVGAARAAAHLTVIEKLRIVVPLK--------DTRVKEQQEVVFNCEVNTEG---AKA 6365
Query: 558 MWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVV 617
W R ++AI + S I + TL I A DD Y+++L N GE S +V
Sbjct: 6366 KWFRNEEAIFDSSKYIILQK-DLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSAANLIV 6424
Query: 618 DFPDPPVAPTVTEV 631
+ D + + ++
Sbjct: 6425 EEEDLRIVEPLKDI 6438
Score = 143 bits (360), Expect = 1e-33
Identities = 99/322 (30%), Positives = 145/322 (45%), Gaps = 23/322 (7%)
Query: 519 IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESY 578
ID P LD D + V AG LE I G+P P +WS+ K + E + R+ +S
Sbjct: 18397 IDAPNASLDPKYKD-VIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKST 18455
Query: 579 PDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT-VTEVGDDWCI 637
+TLV+ R D G Y + L N G I VKV+D P PP P VT V + C
Sbjct: 18456 IQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCY 18515
Query: 638 MNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAV 697
+ W PP DGG+ I Y IE+++ W +++ ++ + ++ K++ G Y R+ AV
Sbjct: 18516 LAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEV-QALNYKVTKLLPGNEYIFRVMAV 18574
Query: 698 NAIGISKP--SMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLE 755
N GI +P S P P PP+ V ++T ++ + W P G ++GY+LE
Sbjct: 18575 NKYGIGEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILE 18634
Query: 756 YCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNA 815
+ D+ G W NK + + +TGL RV A NA
Sbjct: 18635 ----------KRDKEGVR--------WTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENA 18676
Query: 816 AGASEPKYYSQPILVKEIIEPP 837
AG EP S + + PP
Sbjct: 18677 AGVGEPSEPSVFYRACDALYPP 18698
Score = 140 bits (352), Expect = 9e-33
Identities = 97/357 (27%), Positives = 171/357 (47%), Gaps = 39/357 (10%)
Query: 496 EDEGDYVF---APDAYNVTLPAK----VHVID---PPKIILDGLDADNTVTVIAGNKLRL 545
E++ Y F A A N++ P++ V ++ PP+I L + + +TV AG + L
Sbjct: 12952 EEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLS-VAMKSLLTVKAGTNVCL 13010
Query: 546 EIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEA 605
+ + G+P P W + D +++ + I+ + TL + R DSG Y I +N +
Sbjct: 13011 DATVFGKPMPTVSWKK-DGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSS 13069
Query: 606 GEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSR 665
G A+IK+KV+D P PP + + ++ D +++WEPP DGGS I Y +++++
Sbjct: 13070 GSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPN 13129
Query: 666 WMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGI-----SKPSMPSRPFVPLAVTSP 720
W +++ + T+ +K+IEG Y+ RI A N G+ ++P++ P+ P P
Sbjct: 13130 WAQVSATV-PITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDP 13188
Query: 721 PTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAE 780
P + ++T +T+ W+PP G + + GY+LE + A
Sbjct: 13189 P---VISNITKDHMTVSWKPPADDGGSPITGYLLE------------------KRETQAV 13227
Query: 781 DWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPP 837
+W N+ I + TGL + RV A+N AG +P S+ ++ PP
Sbjct: 13228 NWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPP 13284
Score = 139 bits (350), Expect = 2e-32
Identities = 112/414 (27%), Positives = 188/414 (45%), Gaps = 21/414 (5%)
Query: 270 VRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDE 329
+ F V + + KW KNG EI+ + K K L I N D ++Y AG
Sbjct: 2940 ITFEVTVNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKA 2999
Query: 330 KCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRY 389
+ L+V I K ++D +R ECEVSE D V+W K+ +E+ R
Sbjct: 3000 TSTATLYVEARHIEFRKHIKDIKVLEKKRAMFECEVSEPDITVQWMKDDQEL--QITDRI 3057
Query: 390 RIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKE 449
+I+ E H L+I +DA +Y+V+ G S+AKL V+ + ++I + + V +
Sbjct: 3058 KIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEKQR 3117
Query: 450 ICLKCEISE-NIPGKWTKNGLPV--QESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPD 506
++ E++E ++ W K+G+ + Q +R K V + RIH++ I+ D G+Y F
Sbjct: 3118 AVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAG 3177
Query: 507 AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAI 566
++ V+ +PP++ L VTV +G R ISG P PK W + ++ +
Sbjct: 3178 RNRSSVTLYVNAPEPPQV----LQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLL 3233
Query: 567 MEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG----EAHASIKVKVVDFPD- 621
G + + TL++ A +D+ VY KN+ G A S++V V PD
Sbjct: 3234 STGF-KCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQ 3292
Query: 622 --PPVAPTVTEVGDDWCIMNWEPPAY----DGGSPILGYFIERKKKQSSRWMRL 669
P P + D +P + G + ++ + KK + SR+ R+
Sbjct: 3293 EMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRM 3346
Score = 137 bits (344), Expect = 8e-32
Identities = 104/360 (28%), Positives = 172/360 (47%), Gaps = 10/360 (2%)
Query: 272 FVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKC 331
F VEL+ + VKW+KN Q + + + +G + + + D S+ V A
Sbjct: 5643 FTVELSHDNIRVKWFKNDQRLHTTRSVSMQDEGKTHSITFKDLSIDDTSQIRVEAMGMSS 5702
Query: 332 STELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRI 391
+L V E T +L+D T + V L+CE+S+ DA VKWFK+G+EI P + I
Sbjct: 5703 EAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISKADAPVKWFKDGKEIKPSKNA--VI 5760
Query: 392 RVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEIC 451
+ +GKK +LI++ A K+D +Y+ ++S KL ++ + +K++ PL V +
Sbjct: 5761 KADGKKRMLILKKALKSDIGQYTCDCGTDKTSGKLDIEDREIKLVRPLHSVEVMETETAR 5820
Query: 452 LKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNV 510
+ EISE +I W G + ++ ++ +G+IH LV+ N + G F A NV
Sbjct: 5821 FETEISEDDIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTGGVDF--QAANV 5878
Query: 511 TLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGS 570
A + V P++I L VTV AG + +S E P + +G K +E S
Sbjct: 5879 KSSAHLRV--KPRVI-GLLRPLKDVTVTAGETATFDCELSYEDIPVEWYLKGKK--LEPS 5933
Query: 571 GRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTE 630
++ S TL + + +D+G + K+ A+ +K V+F P TV E
Sbjct: 5934 DKVVPRSEGKVHTLTLRDVKLEDAGEVQLTAKDFKTHANLFVKEPPVEFTKPLEDQTVEE 5993
Score = 137 bits (344), Expect = 8e-32
Identities = 134/554 (24%), Positives = 209/554 (37%), Gaps = 88/554 (15%)
Query: 617 VDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKE 676
+D P PP PTV +VG +NW P +DGG+ I Y IE K + W+R+ +
Sbjct: 7676 IDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTT 7735
Query: 677 TTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTT 733
P M EG Y R+ AVN G S+PS PS P + L SPP L V ++T T
Sbjct: 7736 QHLLPGLM-EGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNT 7794
Query: 734 VTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKT 793
++W P+ G + + Y++E D+ + W + + D T
Sbjct: 7795 ADLKWTVPEKDGGSPITNYIVE------------------KRDVRRKGWQTVDTTVKD-T 7835
Query: 794 KFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRV 853
K T+T L + RV A NA G S+ +L K+ P
Sbjct: 7836 KCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTP---------------- 7879
Query: 854 GEAVNLVIPFQGKPRPELTW---KKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYD 910
G L + K +L W K DG + + + T R + + D
Sbjct: 7880 GPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGT----RWVKAGKTAGPD 7935
Query: 911 LQVKVDKFVETASIDIQI-----------------------IDRPGPPQIVKIEDVWGEN 947
+V +E + Q+ P PP + + D ++
Sbjct: 7936 CNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKH 7995
Query: 948 VALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITE--LVIGNEYYFRV 1005
+A+ W PP+ +G + I GY ++ + +W V + E +V EY RV
Sbjct: 7996 IAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRV 8055
Query: 1006 FSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNAT 1065
+ N G+SE + +++ V+A+D E D I G +
Sbjct: 8056 RAVNAIGVSEPSEISEN--VVAKDPDCKPTIDLETHDI-------------IVIEGEKLS 8100
Query: 1066 LNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDL 1125
+ R P P ++W K+ + R M ++ LE+ K D G Y N L
Sbjct: 8101 IPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKL 8160
Query: 1126 GTVEIECKLEVKVI 1139
G+ + VKVI
Sbjct: 8161 GSA--TASINVKVI 8172
Score = 136 bits (343), Expect = 1e-31
Identities = 105/376 (27%), Positives = 169/376 (44%), Gaps = 13/376 (3%)
Query: 247 EEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQ 306
+ K+ F + L +K F E ++P ++VKWYK+G E+ KY
Sbjct: 2123 QAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKV 2182
Query: 307 RILFINNCQMTDDSEY-YVTAGDE--KCSTELFVREPPIMVTKQLEDTTAYCGERVELEC 363
L I +D +Y V DE K + +L V + K+L+D ELEC
Sbjct: 2183 HFLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGELEC 2242
Query: 364 EVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSS 423
VS ++ KW+ N E+ +Y I + L ++ TK D EYS + G +++
Sbjct: 2243 IVSPENIEGKWYHNDVEL--KSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTT 2300
Query: 424 AKLSVDLKPLKILTPLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKVVHK 482
KL + +P+ IL L+DQ V G + L+ ++S E++ G W K+G VQ SDR+ +V
Sbjct: 2301 CKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVID 2360
Query: 483 GRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNK 542
+ H L+I + ED G+Y F A ++ +V V +D + V VI G K
Sbjct: 2361 KQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYS-----VDVITPLKDVNVIEGTK 2415
Query: 543 LRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLK 602
LE +S W D+ I + R++ LVI+ D G Y + +
Sbjct: 2416 AVLECKVSVPDVTSVKWYLNDEQI-KPDDRVQAIVKGTKQRLVINRTHASDEGPYKLIVG 2474
Query: 603 NEAGEAHASI-KVKVV 617
+ S+ K+K++
Sbjct: 2475 RVETNCNLSVEKIKII 2490
Score = 133 bits (335), Expect = 8e-31
Identities = 197/836 (23%), Positives = 326/836 (38%), Gaps = 110/836 (13%)
Query: 337 VREPPIMVTKQLEDTTAY-CGERVELECEVS-EDDANVKWFKNGEEIIPGPKSRYRIRVE 394
V P I V + +DT GE LE +VS ++W K+G+E+ ++ I++
Sbjct: 15151 VEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKEL--EGTAKLEIKIA 15208
Query: 395 GKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKC 454
L+ + +T+ D+ Y++ T AK ++K L P + + + + KC
Sbjct: 15209 DFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGP-PEGPLAVTEVTSEKC 15267
Query: 455 EISENIP-----GKWTKNGLPVQESDRL---KVVHKGRIHKLVIANALTEDEGDY-VFAP 505
+S P K + +E+ RL V + ++ KL + L +E + V A
Sbjct: 15268 VLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAV 15327
Query: 506 DAYNVTLPAKVHVI---------DPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPK 556
+ Y V P + + DPPK + VT I + + + G P
Sbjct: 15328 NKYGVGEPLESEPVLAVNPYGPPDPPK--------NPEVTTITKDSM---VVCWGHPDSD 15376
Query: 557 A-------MWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG--- 606
+ R DKA + ++ D V + E + + I +N AG
Sbjct: 15377 GGSEIINYIVERRDKAGQRWI-KCNKKTLTDLRYKVSGLTEGHEYE-FRIMAENAAGISA 15434
Query: 607 EAHASIKVKVVDF---PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQS 663
+ S K D P PP P V + + W P YDGGS I GY +E +
Sbjct: 15435 PSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEE 15494
Query: 664 SRWMRLNFDL-CKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSM-PSRPFVPLAVTSPP 721
W + K T++ + E Y++RI+A+N+ G+ +P++ P P + P
Sbjct: 15495 DEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPE 15554
Query: 722 TLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAED 781
L D T+ + G +++ + S ++ ++Y L
Sbjct: 15555 IELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESLDKASIESTSSYTL---- 15610
Query: 782 WIVANKDLIDKTKF--TITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEII----- 834
IV N + D K+ T+ FV V+ ++ G Q + VKE+
Sbjct: 15611 LIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPP------QDLKVKEVTKTSVT 15664
Query: 835 ---EPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSE 891
+PP + +K YI E+ + +WK D + E
Sbjct: 15665 LTWDPPLLDGGSKIKN-YIVEKRESTRKAYSTVATNCHKTSWKVDQLQ-----------E 15712
Query: 892 TDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALT 951
+ F AE + + ETA ++ +RP PP + + DV +V+L+
Sbjct: 15713 GCSYYFRVLAENEYG--------IGLPAETAE-SVKASERPLPPGKITLMDVTRNSVSLS 15763
Query: 952 WTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMC 1011
W P+ DG + I GY ++ K S +W T T ATIT L+ G EY FRV ++N
Sbjct: 15764 WEKPEHDGGSRILGYIVEMQTKGSDKWATCAT-VKVTEATITGLIQGEEYSFRVSAQNEK 15822
Query: 1012 GLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI-AGYNATLNCSV 1070
G+S+ ++ VIA+D I P + L NT+ + AG + ++
Sbjct: 15823 GISDPRQLSVP--VIAKDLVI--------------PPAFKLLFNTFTVLAGEDLKVDVPF 15866
Query: 1071 RGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLG 1126
G P P +TW K+ V + R S + L I+ D G Y K N G
Sbjct: 15867 IGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAG 15922
Score = 133 bits (335), Expect = 8e-31
Identities = 89/320 (27%), Positives = 152/320 (47%), Gaps = 26/320 (8%)
Query: 522 PKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS 581
P L G+ + +T AG+ +++PISG P PK W + + E + R+ + D
Sbjct: 22340 PTADLTGI-TNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKE-TDRVSITTTKDR 22397
Query: 582 STLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT-VTEVGDDWCIMNW 640
+TL + + R DSG Y + L+N AG S+ V V+ P P P V+ V + C+++W
Sbjct: 22398 TTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLSW 22457
Query: 641 EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAI 700
P GG+ I Y +E+++ ++ W +N + K T + + + + Y R+ + N
Sbjct: 22458 GEPKDGGGTEITNYIVEKRESGTTAWQLVNSSV-KRTQIKVTHLTKYMEYSFRVSSENRF 22516
Query: 701 GISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 757
G+SKP + S P + P S PT V V+ +++RW P H G + + GY +E
Sbjct: 22517 GVSKP-LESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVE-- 22573
Query: 758 FEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAG 817
+ + N W+ NK + + +TGL + R A+NAAG
Sbjct: 22574 --------KKERNTIL--------WVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAG 22617
Query: 818 ASEPKYYSQPILVKEIIEPP 837
S+ S+PI+ + ++ P
Sbjct: 22618 VSKASEASRPIMAQNPVDAP 22637
Score = 131 bits (329), Expect = 4e-30
Identities = 159/630 (25%), Positives = 262/630 (41%), Gaps = 95/630 (15%)
Query: 267 GGRVRFVVELAD-PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVT 325
GG +R V + P EVKW K EIR + I + L ++N D +Y +T
Sbjct: 16652 GGSLRLFVPIKGRPTPEVKWGKVDGEIRDAA--IIDVTSSFTSLVLDNVNRYDSGKYTLT 16709
Query: 326 AGDEKCSTELFVR-------EPPI--MVTKQLEDTTAYCGERVELECE-------VSEDD 369
+ + FV PP+ VT+ +D+ + E L+ V + +
Sbjct: 16710 LENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKRE 16769
Query: 370 ANVKWF--------KNG---EEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTT 418
A K + KN +++ G +R+ E + I A A+ +
Sbjct: 16770 ATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGI-----GLPAQTADPIKVAE 16824
Query: 419 GGQSSAKLSVDLKPLKILTPLTDQTVNLG---KEICLKCEISENIPGKWTKNGLPVQESD 475
Q K++VD +T +V+L E +I + I K+ E
Sbjct: 16825 VPQPPGKITVD--------DVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECA 16876
Query: 476 RLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYN-----------VTLPAKVHVIDPPKI 524
R+K + + VI N LT+ E +Y+F A N V + AK VI+P
Sbjct: 16877 RVKSL------QAVITN-LTQGE-EYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEP--- 16925
Query: 525 ILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTL 584
D A ++ +V G L++E+PISG P P W++ D ++ + RI D +TL
Sbjct: 16926 --DVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTK-DGLPLKQTTRINVTDSLDLTTL 16982
Query: 585 VIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT-VTEVGDDWCIMNWEPP 643
I +DD G Y I + N G+ ASI++ +D PDPP P +V + ++W PP
Sbjct: 16983 SIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPP 17042
Query: 644 AYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGIS 703
Y GG I Y ++++ ++ W ++ + + TT + K+ G Y+ RIFA N G S
Sbjct: 17043 LYTGGCQITNYIVQKRDTTTTVWDVVSATVAR-TTLKVTKLKTGTEYQFRIFAENRYGQS 17101
Query: 704 KPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEG 760
++ S P V P PP +++ ++ ++W P + G + + GY LE
Sbjct: 17102 F-ALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLE----- 17155
Query: 761 STSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASE 820
+ + N W NK +I T+F L + RV A N G +
Sbjct: 17156 -----RKERNSIL--------WTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGK 17202
Query: 821 PKYYSQPILVKEIIEPPKIRIPRHLKQTYI 850
S+ + ++ +PP P +K+ I
Sbjct: 17203 ASKNSECYVARDPCDPPGTPEPIMVKRNEI 17232
Score = 131 bits (329), Expect = 4e-30
Identities = 92/316 (29%), Positives = 146/316 (46%), Gaps = 25/316 (7%)
Query: 521 PPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPD 580
PPK LD + VT+ AG+ L L+ + G+P PK +W++GDK ++ ++ +
Sbjct: 22738 PPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKE-LDLCEKVSLQYTGK 22796
Query: 581 SSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNW 640
+T VI +R DSG Y + +KN +G S+ VKV+D P P TV+ V + C + W
Sbjct: 22797 RATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAW 22856
Query: 641 EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAI 700
P DGG+ I Y +ER++ W+ + + C ++ ++I+ Y R+ AVN
Sbjct: 22857 SLPQEDGGAEITHYIVERRETSRLNWVIVEGE-CPTLSYVVTRLIKNNEYIFRVRAVNKY 22915
Query: 701 GISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 757
G P + S P V + SPP + + ++W P+ G + Y+++
Sbjct: 22916 GPGVP-VESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKR 22974
Query: 758 FEGSTSAKQSDENGEAAYDLPAEDWIVANKD-LIDKTKFTITGLPTDAKIFVRVKAVNAA 816
+ S W NKD ++ T+ +T L RV AVNAA
Sbjct: 22975 EKKSLR------------------WTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAA 23016
Query: 817 GASEPKYYSQPILVKE 832
G SEP S I +E
Sbjct: 23017 GNSEPSEASNFISCRE 23032
Score = 130 bits (328), Expect = 5e-30
Identities = 80/234 (34%), Positives = 120/234 (51%), Gaps = 8/234 (3%)
Query: 272 FVVELADPKLE-VKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEK 330
F VEL P ++ V+W KNG + + KY KG L I NC + D+S Y G
Sbjct: 2680 FTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGFRLGRLG 2739
Query: 331 CSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYR 390
S L V + + K+ +D TA V E VS D VKWF EI P K +R
Sbjct: 2740 ASARLHVET--VKIIKKPKDVTALENATVAFEVSVSHDTVPVKWFHKSVEIKPSDK--HR 2795
Query: 391 IRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEI 450
+ E K H L+++ + +DA EY+ + GQ K + ++ L I + + V K
Sbjct: 2796 LVSERKVHKLMLQNISPSDAGEYTAVV--GQLECKAKLFVETLHITKTMKNIEVPETKTA 2853
Query: 451 CLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF 503
+CE+S N+P W KNG+ ++ S++ K+V +G++H+L+I N TED +Y F
Sbjct: 2854 SFECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTF 2907
Score = 130 bits (328), Expect = 5e-30
Identities = 91/320 (28%), Positives = 147/320 (45%), Gaps = 24/320 (7%)
Query: 522 PKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS 581
P I+ G + + + + +G LR++ + G P P+ W + D +E + S
Sbjct: 21650 PPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFK-DGVEIEKRMNMEITDVLGS 21708
Query: 582 STLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT-VTEVGDDWCIMNW 640
++L + A RD GVY + KN +G A A IKVKV D P V P T + + + W
Sbjct: 21709 TSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWW 21768
Query: 641 EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAI 700
+ P DG +PI Y IE+++ W + D C+ ++ K+I G Y+ R+ AVN
Sbjct: 21769 DAPLNDGCAPITHYIIEKRETSRLAWALIE-DKCEAQSYTAIKLINGNEYQFRVSAVNKF 21827
Query: 701 GISKP--SMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCF 758
G+ +P S P + V P + ++T ++T+ W P+ G + + Y+LE
Sbjct: 21828 GVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERRE 21887
Query: 759 EGSTSAKQSDENGEAAYDLPAEDWI-VANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAG 817
+ ST W+ V +K I +T+F +TGL + V A NAAG
Sbjct: 21888 KKSTR------------------WVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAG 21929
Query: 818 ASEPKYYSQPILVKEIIEPP 837
S+ I +E + PP
Sbjct: 21930 VGPASGISRLIKCREPVNPP 21949
Score = 128 bits (322), Expect = 3e-29
Identities = 101/352 (28%), Positives = 164/352 (46%), Gaps = 15/352 (4%)
Query: 264 VDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYY 323
V +G FV EL+ K+ V W+KN ++ S + +G L + + D S+
Sbjct: 5280 VKEGETATFVCELSHEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIK 5339
Query: 324 VTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIP 383
+ + +L V E T +L D TA + + L+CEVS+ D VKWFK+GEEI+P
Sbjct: 5340 AQVKELSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSK-DVPVKWFKDGEEIVP 5398
Query: 384 GPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQT 443
PK Y I+ +G + IL I+ A D EY ++ A ++V+ + +K+ PL
Sbjct: 5399 SPK--YSIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPLYGVE 5456
Query: 444 VNLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV 502
V +G+ + E+SE ++ G+W G P+ S +++ G+ H L++ N G+
Sbjct: 5457 VFVGETAHFEIELSEPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTGEVS 5516
Query: 503 FAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRG 562
F A N A + V + P I + L + V V ++ + E +S E P W +G
Sbjct: 5517 F--QAANAKSAANLKVKELPLIFITPL---SDVKVFEKDEAKFECEVSRE-PKTFRWLKG 5570
Query: 563 DKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKV 614
+ I G R ++VI A +D Y EA + H S K+
Sbjct: 5571 TQEI-TGDDRFELIKDGTKHSMVIKSAAFEDEAKYMF----EAEDKHTSGKL 5617
Score = 127 bits (319), Expect = 6e-29
Identities = 199/857 (23%), Positives = 322/857 (37%), Gaps = 121/857 (14%)
Query: 319 DSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAY-CGERVELECEV-SEDDANVKWFK 376
DS +TA DE V P I + + DT GE LE +V + ++W +
Sbjct: 17304 DSTGPITAKDE-------VELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLR 17356
Query: 377 NGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKIL 436
+EI +R I+ K +LI++ A + D +Y + + S V++K L
Sbjct: 17357 GDKEI--EESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRP 17414
Query: 437 TPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVVHKGRIHKL-------- 488
P + V + KC ++ + P + G + VV K +L
Sbjct: 17415 GP-PEGPVQVTGVTSEKCSLTWSPPLQ--DGGSDISHY----VVEKRETSRLAWTVVASE 17467
Query: 489 VIANALTEDE----GDYVF---APDAYNVTLPAK-VHVIDPPKIILDGLDADNTVTVIAG 540
V+ N+L + +YVF A + Y V P + V+ +L G VT IA
Sbjct: 17468 VVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAK 17527
Query: 541 NKLRLEIPISGEPPPKAMWSRGDKA--------IMEGSGRIRTESYPDSSTLVIDIAER- 591
+ + + W+R D I+E R + + D+ R
Sbjct: 17528 DSMTV------------CWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRV 17575
Query: 592 -----DDSGVYHINLKNEAGEAH---ASIKVKVVD---FPDPPVAPTVTEVGDDWCIMNW 640
D + ++ +N AG A++ K D P PP + + + + W
Sbjct: 17576 TGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAW 17635
Query: 641 EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDL-CKETTFEPKKMIEGVAYEVRIFAVNA 699
P YDGGS ILGY +E K W + + T FE K+ E Y++R+ A+N
Sbjct: 17636 GKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNK 17695
Query: 700 IGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFE 759
+G+ + + P P L +DS + +R A G + +
Sbjct: 17696 VGLGEATSVPGTVKPEDKLEAPEL-DLDSELRKGIVVR--------AGGSARIHIPFKGR 17746
Query: 760 GSTSAKQSDENGEAAYDLPAEDWI------VANKDLIDKTKFTIT--GLPTDAKIFVRVK 811
+ S E GE + E + + N D D K+ + FV VK
Sbjct: 17747 PTPEITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVK 17806
Query: 812 AVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPEL 871
++ G Q + VKE+ + + + I + N VI + R
Sbjct: 17807 VLDTPGPP------QNLAVKEVRKDSAFLV---WEPPIIDGGAKVKNYVIDKRESTRK-- 17855
Query: 872 TWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDR 931
+ ++ K + N I + R + G V VET ++ +
Sbjct: 17856 AYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFG-------VGVPVETVDA-VKAAEP 17907
Query: 932 PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSAT 991
P PP V + DV + +L W P+ DG + + GY ++ K + +W V E +A
Sbjct: 17908 PSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAES-KVCNAV 17966
Query: 992 ITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQ 1051
+T L G EY FRV + N G S+ + VIA+D I P
Sbjct: 17967 VTGLSSGQEYQFRVKAYNEKGKSDPRVLGVP--VIAKDLTIQ-------------PSLKL 18011
Query: 1052 PLVNTYAI-AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPS 1110
P NTY+I AG + + V G P+P I+W+K+ + R + L I++ +
Sbjct: 18012 PF-NTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGN 18070
Query: 1111 PYDGGTYCCKAVNDLGT 1127
D G Y A N GT
Sbjct: 18071 KDDFGKYTVTATNSAGT 18087
Score = 126 bits (316), Expect = 1e-28
Identities = 125/552 (22%), Positives = 221/552 (40%), Gaps = 66/552 (11%)
Query: 597 YHINLKNEAG---EAHASIKVKVVD---FPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSP 650
Y + +N AG + S ++ D P PP P + + G + W P +DGG+P
Sbjct: 19750 YRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAP 19809
Query: 651 ILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSR 710
I GY +E KK + W + + + T + + G Y R+ +VN +G S PS S
Sbjct: 19810 ITGYTVEYKKSDDTDW-KTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSD 19868
Query: 711 PFVPLAVTSPP----------TLLTVDSVTDT-TVTMRWRPPDHIGAAGLDGYVLEYCFE 759
P + P TL+ + T TV R RP ++ + D + +
Sbjct: 19869 PQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYV 19928
Query: 760 GSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGAS 819
+T ++ S L E+ AN++ K TI + + A + + VK ++ G
Sbjct: 19929 DTTDSRTS---------LTIEN---ANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGPP 19976
Query: 820 EPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAE 879
I V+++ + + L G A + + + W
Sbjct: 19977 TN------ITVQDVTKESAV-----LSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNN 20025
Query: 880 IDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVK 939
++ + N + I + R SG+ + V + ET ++I ++P PP+ +
Sbjct: 20026 CNRLSYKVTNLQEGAIYYFRV-----SGENEFGVGIP--AETKE-GVKITEKPSPPEKLG 20077
Query: 940 IEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF--TVIEHYHRTSATITELVI 997
+ + ++V+LTW P+ DG + I Y ++ +K W V + H + + E
Sbjct: 20078 VTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKCAVAKSTHHVVSGLRE--- 20134
Query: 998 GNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTY 1057
+EY+FRVF+EN GLS+ + + + E + E M P Y
Sbjct: 20135 NSEYFFRVFAENQAGLSDPREL------------LLPVLIKEQLEPPEIDMKNFPSHTVY 20182
Query: 1058 AIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTY 1117
AG N ++ + G P PK+T ++ V + R+ T+ +++ D G Y
Sbjct: 20183 VRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRY 20242
Query: 1118 CCKAVNDLGTVE 1129
A N GT +
Sbjct: 20243 EITAANSSGTTK 20254
Score = 125 bits (315), Expect = 2e-28
Identities = 87/266 (32%), Positives = 123/266 (46%), Gaps = 11/266 (4%)
Query: 247 EEKKSAAFAKIL--DPAYQV---DKGGRVRFVVEL---ADPKLEVKWYKNGQEIRPSTKY 298
+E S A K+L DP + V DK + + L + VKW+K+G+EI PS KY
Sbjct: 5343 KELSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSKDVPVKWFKDGEEIVPSPKY 5402
Query: 299 IFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGER 358
+ G +RIL I + D EY G +K + V I V K L + GE
Sbjct: 5403 SIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPLYGVEVFVGET 5462
Query: 359 VELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTT 418
E E+SE D + +W G+ + P I +GKKHILI+ E S
Sbjct: 5463 AHFEIELSEPDVHGQWKLKGQPLTASPDC--EIIEDGKKHILILHNCQLGMTGEVSFQAA 5520
Query: 419 GGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRL 477
+S+A L V PL +TPL+D V E +CE+S E +W K + DR
Sbjct: 5521 NAKSAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPKTFRWLKGTQEITGDDRF 5580
Query: 478 KVVHKGRIHKLVIANALTEDEGDYVF 503
+++ G H +VI +A EDE Y+F
Sbjct: 5581 ELIKDGTKHSMVIKSAAFEDEAKYMF 5606
Score = 124 bits (312), Expect = 4e-28
Identities = 135/548 (24%), Positives = 203/548 (37%), Gaps = 95/548 (17%)
Query: 620 PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDL-CKETT 678
P PP P V + ++W PAYDGGSPI+GY +E K+ S W+R N ++T
Sbjct: 13284 PGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTR 13343
Query: 679 FEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPP----------TLLTVDS 728
FE ++E Y+ R++AVN IG S PS P + PP TL+
Sbjct: 13344 FEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAG 13403
Query: 729 VTDTT-VTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANK 787
VT V ++ RPP P W N
Sbjct: 13404 VTMRLYVPVKGRPP------------------------------------PKITWSKPNV 13427
Query: 788 DLIDKTKFTITGLPTDAKIFVRVKAVNAAGASE----------PKYYSQPILVKEIIEPP 837
+L D+ I TD F+R + VN A + K Y+ + V + PP
Sbjct: 13428 NLRDRIGLDIKS--TDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPP 13485
Query: 838 -KIRIPRHLKQT--------YIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIR 888
+ + K + I +N V+ Q + +W E K +
Sbjct: 13486 VNVTVKEISKDSAYVTWEPPIIDGGSPIINYVV--QKRDAERKSWSTVTTECSKTSFRVA 13543
Query: 889 NSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENV 948
N E F R + G D D ++ PGP +K+ V +
Sbjct: 13544 NLEEGKSYFFRVFAENEYGIGDPGETRDA--------VKASQTPGPVVDLKVRSVSKSSC 13595
Query: 949 ALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSE 1008
++ W P DG + I GY + +++ +W V++ + +L G EY FRV +E
Sbjct: 13596 SIGWKKPHSDGGSRIIGYVVDFLTEEN-KWQRVMKSLS-LQYSAKDLTEGKEYTFRVSAE 13653
Query: 1009 NMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNC 1068
N G + +T V+ARD + V D D P A N L
Sbjct: 13654 NENGEGTPSEIT----VVARD-----DVVAPDLDLKGLPDLCY-----LAKENSNFRLKI 13699
Query: 1069 SVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTV 1128
++G P P ++W K + + D R + S+ TL + D G Y N GT
Sbjct: 13700 PIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTK 13759
Query: 1129 EIECKLEV 1136
E ++V
Sbjct: 13760 EGTISIKV 13767
Score = 120 bits (301), Expect = 7e-27
Identities = 130/513 (25%), Positives = 208/513 (40%), Gaps = 41/513 (7%)
Query: 96 KGKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSF 155
KG+W+ + GKHL L S + + I K + G Y TYK S
Sbjct: 2603 KGEWL----RDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEY----TYKVATSKTSA 2654
Query: 156 DLEVH--ESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWEL 213
L+V + T N+ + + + +K V + E+ + V
Sbjct: 2655 KLKVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISV--- 2711
Query: 214 LKNAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVD--KGGRVR 271
K + Y I D RL R+ + KI+ V + V
Sbjct: 2712 ----KGTIYSLRIKNCAIVDESVYGFRLGRLGASARLHVETVKIIKKPKDVTALENATVA 2767
Query: 272 FVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKC 331
F V ++ + VKW+ EI+PS K+ + L + N +D EY G +C
Sbjct: 2768 FEVSVSHDTVPVKWFHKSVEIKPSDKHRLVSERKVHKLMLQNISPSDAGEYTAVVGQLEC 2827
Query: 332 STELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRI 391
+LFV + +TK +++ + ECEVS + W KNG EI K ++I
Sbjct: 2828 KAKLFVE--TLHITKTMKNIEVPETKTASFECEVSHFNVPSMWLKNGVEIEMSEK--FKI 2883
Query: 392 RVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEIC 451
V+GK H LII + D+AEY+ + Q SA L+V P+ I + L D +N ++
Sbjct: 2884 VVQGKLHQLIIMNTSTEDSAEYTFVCGNDQVSATLTV--TPIMITSMLKD--INAEEKDT 2939
Query: 452 LKCEISENIPG---KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPD-- 506
+ E++ N G KW KNG+ ++ +D+ ++ K H L I N D DY F
Sbjct: 2940 ITFEVTVNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKA 2999
Query: 507 AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAI 566
TL + I+ K I D + V+ + E +S EP W + D+
Sbjct: 3000 TSTATLYVEARHIEFRKHIKD-------IKVLEKKRAMFECEVS-EPDITVQWMKDDQE- 3050
Query: 567 MEGSGRIRTESYPDSSTLVIDIAERDDSGVYHI 599
++ + RI+ + L+I D+G Y +
Sbjct: 3051 LQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTV 3083
Score = 120 bits (301), Expect = 7e-27
Identities = 89/317 (28%), Positives = 143/317 (45%), Gaps = 11/317 (3%)
Query: 256 KILDPAYQVD--KGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINN 313
K++ P + V+ + RF E+++ + W G+ + + + +G L ++N
Sbjct: 5803 KLVRPLHSVEVMETETARFETEISEDDIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHN 5862
Query: 314 CQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVK 373
C++ A + K S L V+ I + + L+D T GE +CE+S +D V+
Sbjct: 5863 CRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCELSYEDIPVE 5922
Query: 374 WFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPL 433
W+ G+++ P K R EGK H L + DA E + ++ A L V P+
Sbjct: 5923 WYLKGKKLEPSDK--VVPRSEGKVHTLTLRDVKLEDAGEVQLTAKDFKTHANLFVKEPPV 5980
Query: 434 KILTPLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIAN 492
+ PL DQTV G L+CE+S EN KW KNG + +S + ++V GR+ KLVI +
Sbjct: 5981 EFTKPLEDQTVEEGATAVLECEVSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHD 6040
Query: 493 ALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGE 552
ED Y DA + ++V+ P L L + V R E +S E
Sbjct: 6041 CTPEDIKTYTC--DAKDFKTSCNLNVVPPHVEFLRPL---TDLQVREKEMARFECELSRE 6095
Query: 553 PPPKAMWSRGDKAIMEG 569
K W + I +G
Sbjct: 6096 -NAKVKWFKDGAEIKKG 6111
Score = 120 bits (301), Expect = 7e-27
Identities = 124/479 (25%), Positives = 201/479 (41%), Gaps = 76/479 (15%)
Query: 463 KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY--VFAPDAYNVTLPAKVHVID 520
KWTK G + S R + +LVI A D G Y V + KV VI
Sbjct: 23864 KWTKEGQDI--SKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIG 23921
Query: 521 PPKIILDGLDADNTVTVIAGNKLRLEIPISGEPP------------------PKAMWSRG 562
P L+ D+ + +S PP PKA W
Sbjct: 23922 SPNSPEGPLEYDDIQV--------RSVRVSWRPPADDGGADILGYILERREVPKAAWYTI 23973
Query: 563 DKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG-----EAHASIKVKV- 616
D R+R ++LV+ + + + ++ +N+ G ++ + K
Sbjct: 23974 DS-------RVR------GTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTP 24020
Query: 617 VDFPDPPV-APTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCK 675
++ P+PP P V +V ++W P DGGS + GY+IERK+ + +W+R N
Sbjct: 24021 LNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQIT 24080
Query: 676 ETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDT 732
T + ++ Y+ RI A N +G+S+ S S P V P S P L + S++
Sbjct: 24081 TTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKD 24140
Query: 733 TVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDK 792
+VT++W P+ G + GY +EY ++G++A W +NK+ I
Sbjct: 24141 SVTLQWEKPECDGGKEILGYWVEY-----------RQSGDSA-------WKKSNKERIKD 24182
Query: 793 TKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEII-EPPKIRIPRHLKQTYIR 851
+FTI GL + RV A N G S P+ + I K E P IR + +K
Sbjct: 24183 KQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIR--KEMKDV-TT 24239
Query: 852 RVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDT-IIFIRKAERSHSGKY 909
++GEA L G+P P++ W + G E+ +++ +S+ T + + E+ G Y
Sbjct: 24240 KLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVY 24298
Score = 118 bits (295), Expect = 4e-26
Identities = 143/575 (24%), Positives = 215/575 (37%), Gaps = 93/575 (16%)
Query: 597 YHINLKNEAGEAHASIKVKVVDF------PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSP 650
+ ++ +NE G S K V P PPV P + + + W+PP +DGGS
Sbjct: 10779 FRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSK 10838
Query: 651 ILGYFIERKKKQSSRWMRLNF--DLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMP 708
ILGY +E +K W R N + C ET ++ + +G Y+ R+ AVNA G S P+
Sbjct: 10839 ILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHV 10898
Query: 709 SRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSD 768
P + PP L + D + HI D L +G
Sbjct: 10899 PEPVLVKDRLEPPEL-----ILDANMARE----QHIKVG--DTLRLSAIIKG-------- 10939
Query: 769 ENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAG----ASEPKYY 824
P W ++D K + +T P +K+ +R A G E
Sbjct: 10940 ------VPFPKVTWKKEDRDAPTKARIDVT--PVGSKLEIRNAAHEDGGIYSLTVENPAG 10991
Query: 825 SQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKK---DGAEID 881
S+ + VK ++ K PR L+ + IR K LTWK+ DG +
Sbjct: 10992 SKTVSVKVLVLD-KPGPPRDLEVSEIR--------------KDSCYLTWKEPLDDGGSVI 11036
Query: 882 KNQINIRNSETD---TIIFIRKAERSHSGKY-------------DLQVKVDKFVETASID 925
N + R + + ++SH K+ + Q FVET
Sbjct: 11037 TNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPK-P 11095
Query: 926 IQIIDR---PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVI 982
I+ +D PGPP+ + DV V+L W P DG + ITGY ++ ++ + +W
Sbjct: 11096 IKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIK-F 11154
Query: 983 EHYHRTSATITELVIGNEYYFRVFSENMCGLS-EDATMTKESAVIARDGKIYKNPVYEDF 1041
+ +T L G Y FRV +EN+ GL D T+ E K+ V D
Sbjct: 11155 KTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLPDTTIPIEC-----QEKLVPPSVELDV 11209
Query: 1042 DFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGV 1101
E + AG +RG P P W + I D Y + ++
Sbjct: 11210 KLIEGLVVK---------AGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFS 11260
Query: 1102 CTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
L I+ D G Y N G+ + L V
Sbjct: 11261 SVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 11295
Score = 116 bits (290), Expect = 1e-25
Identities = 185/884 (20%), Positives = 323/884 (36%), Gaps = 156/884 (17%)
Query: 313 NCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDT-TAYCGERVELECEV-SEDDA 370
N DS +TA DE + P + + +D + GE LE ++ +
Sbjct: 18380 NFSEPSDSSGAITARDE-------IDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIP 18432
Query: 371 NVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEY--SVMTTGGQSSAKLSV 428
+V W K+G+E+ +R I+ +K L+++ + D +Y + GG S ++V
Sbjct: 18433 DVVWSKDGKEL-EETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITV 18491
Query: 429 DLK--------PLKIL------------TPLTDQTVNLGKEICLKCEISENIPGKWTKNG 468
+ PLK+ PL D N+ I K E S WT+
Sbjct: 18492 KVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRL---SWTQVS 18548
Query: 469 LPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF---APDAYNVTLPAKVHVID----- 520
VQ + ++ KL+ N +Y+F A + Y + P + +
Sbjct: 18549 TEVQALNY-------KVTKLLPGN-------EYIFRVMAVNKYGIGEPLESGPVTACNPY 18594
Query: 521 -----PPKIILDGLDADNTVTVIA------GNKLRLEIPISGEPPPKAMWSRGDKAIMEG 569
P + + D+ V A G ++ I + W++ +K +
Sbjct: 18595 KPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYI-LEKRDKEGVRWTKCNKKTLTD 18653
Query: 570 SGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGE-AHASIKVKVVDF---PDPPVA 625
R+R + + +A + +GV GE + S+ + D P PP
Sbjct: 18654 L-RLRVTGLTEGHSYEFRVAAENAAGV---------GEPSEPSVFYRACDALYPPGPPSN 18703
Query: 626 PTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETT------F 679
P VT+ + W P YDGG+P+ GY +E K+ + W C T F
Sbjct: 18704 PKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTT-----CTPPTGLQGKQF 18758
Query: 680 EPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTL-----------LTVDS 728
K+ E Y RI A+N+ G+ +P+ V PP + L +
Sbjct: 18759 TVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASA 18818
Query: 729 VTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKD 788
VT++ RP + +G + + TS+ ++ N
Sbjct: 18819 TLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTM--------------LVIDNVT 18864
Query: 789 LIDKTKFTIT--GLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLK 846
D ++ +T FV V+ +++ A P+ + I E K + +
Sbjct: 18865 RFDSGRYNLTLENNSGSKTAFVNVRVLDSPSA--------PVNLT-IREVKKDSVTLSWE 18915
Query: 847 QTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHS 906
I + N ++ + R + K I N + + R S
Sbjct: 18916 PPLIDGGAKITNYIVEKRETTRKAYATITNNCT--KTTFRIENLQEGCSYYFRVLA---S 18970
Query: 907 GKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGY 966
+Y + + + + +++ + P PP V + DV + W P+ DG + ITGY
Sbjct: 18971 NEYGIGLPAE-----TTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGY 19025
Query: 967 TIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVI 1026
++ K S +W T + ATI+ L G EY FRV + N G S+ + VI
Sbjct: 19026 VVEMQTKGSEKWSTCTQ-VKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVP--VI 19082
Query: 1027 ARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVA 1086
ARD +I P P A ++ +G P+ + W K+
Sbjct: 19083 ARDIEI-------------KPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQT 19129
Query: 1087 IVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEI 1130
+ + R + S++ V +L I++ S D GTY N G++ +
Sbjct: 19130 LKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITV 19173
Score = 115 bits (288), Expect = 2e-25
Identities = 180/802 (22%), Positives = 307/802 (38%), Gaps = 107/802 (13%)
Query: 373 KWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKP 432
KW +G EI Y + + +L I+ + D EY + + S ++V L
Sbjct: 11238 KWTTDGSEI--KTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 11295
Query: 433 LKILTPLTDQTVNLG---KEICLKCEISENIPGKWTKNGLPVQESDRLK----VVHKGRI 485
L + P T L + + + + ++ G N + V++ D K VV G
Sbjct: 11296 LDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYI-VEKQDTRKDTWGVVSSGSS 11354
Query: 486 H-KLVIANALTEDEGDYVFAPDAYNV---------TLPAKVHVIDPPKIILDGLDADNTV 535
KL I + + +YVF A N T H PP V
Sbjct: 11355 KTKLKIPHL--QKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSP-----PGKPVV 11407
Query: 536 TVIAGNKLRLE--IPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERD- 592
T I N + +P S P + + + R+ D V + E +
Sbjct: 11408 TDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVNKTPIADLKFRVTGLYEGNT 11467
Query: 593 -DSGVYHINLKNEAGEAHASIKVKV---VDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGG 648
+ V+ NL + + +S +K + P PP+ P + + + + W P DGG
Sbjct: 11468 YEFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGG 11527
Query: 649 SPILGYFIERKKKQSSRWMRLNFD-LCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSM 707
SPILGY +E +K +++W R+N D L ++ F +IEG Y RI A N +G +P
Sbjct: 11528 SPILGYVVECQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRE 11587
Query: 708 PSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAA--GLDGYVLEYCFEGSTSAK 765
+ + + PP + +D +T+R I A G + + EG +
Sbjct: 11588 LAESVIAKDILHPPEV-ELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVR 11646
Query: 766 QSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYS 825
+ + + DLP + + D K+ I+ A N++G ++
Sbjct: 11647 E--KRVDLIQDLPRVELQIKEAVRADHGKYIIS-------------AKNSSG------HA 11685
Query: 826 QPILVKEIIEPPKIRIPRHLKQTYIRRVG--------------EAVNLVIPFQGKPRPEL 871
Q + +++ P ++LK T + + E N ++ ++ KP +
Sbjct: 11686 QGSAIVNVLDRPGPC--QNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYR-KPNQK- 11741
Query: 872 TWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETAS--IDIQII 929
W +++ K I + F AE +V V +ET + + I I
Sbjct: 11742 GWSIVASDVTKRLIKANLLANNEYYFRVCAEN--------KVGVGPTIETKTPILAINPI 11793
Query: 930 DRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTS 989
DRPG P+ + I D V L W P DG + Y +++ K S +W V + + +
Sbjct: 11794 DRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKET 11853
Query: 990 ATITELVIGNEYY-FRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPM 1048
+ + + N+ Y FRV ++N G S+ + E V+ D + P+
Sbjct: 11854 HYMVDRCVENQIYEFRVQTKNEGGESD--WVKTEEVVVKED--------------LQKPV 11897
Query: 1049 FTQPLVNTYAI-AGYNATLNCSVRGNPKPKITWMKNKVA--IVDDPRYRMFSNQGVCTLE 1105
L + AG L VRG P P++ W K+K A + PR ++ +
Sbjct: 11898 LDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFS 11957
Query: 1106 IRKPSPYDGGTYCCKAVNDLGT 1127
+ K DGG Y A N G+
Sbjct: 11958 LTKAKRSDGGKYVVTATNTAGS 11979
Score = 115 bits (288), Expect = 2e-25
Identities = 190/873 (21%), Positives = 328/873 (37%), Gaps = 153/873 (17%)
Query: 324 VTAGDEKCSTELFVREPPIMVTKQLEDT-TAYCGERVELECEV-SEDDANVKWFKNGEEI 381
+TA DE V P I + + +DT + GE +++ ++ + ++W K +E+
Sbjct: 16227 ITARDE-------VDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQEL 16279
Query: 382 IPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTD 441
+R I+ L ++ A + D+ Y + ++V++K L P
Sbjct: 16280 --SNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEG 16337
Query: 442 QTVNLGKEICLKCEISENIPGKWTKNGLPVQE--SDRLKVVHKGR-----IHKLVIANAL 494
V G KC ++ W P+Q+ SD + + + R + +V AN
Sbjct: 16338 PVVISGVT-AEKCTLA------WKP---PLQDGGSDIINYIVERRETSRLVWTVVDANVQ 16387
Query: 495 TED-------EG-DYVF---APDAYNVTLPAKVH--VIDPPKIILDGLDADNTVTVIAGN 541
T EG +Y F A + Y V P + V P ++ D A TV +
Sbjct: 16388 TLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDS 16447
Query: 542 KLRL-EIPISG------------EPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDI 588
+ + E P S W+R K ++ G R+R V +
Sbjct: 16448 MIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLI-GELRLR----------VTGL 16496
Query: 589 AERDDSGVYHINLKNEAGEAHAS---IKVKVVD---FPDPPVAPTVTEVGDDWCIMNWEP 642
E D + ++ +N AG + S K D P PP P V ++ ++W
Sbjct: 16497 IENHDYE-FRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSK 16555
Query: 643 PAYDGGSPILGYFIERKKKQSSRWMRLNFDL-CKETTFEPKKMIEGVAYEVRIFAVNAIG 701
P YDGG I GY +E+ W +T E +K++E Y RI A+N G
Sbjct: 16556 PIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAG 16615
Query: 702 ISKPSMPSRPFVPLAVTSPPTL-----------LTVDSVTDTTVTMRWRPPDHIGAAGLD 750
+ + + P + P + + V ++ RP + +D
Sbjct: 16616 VGEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVD 16675
Query: 751 GYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTIT--GLPTDAKIFV 808
G + + TS+ S ++ N + D K+T+T FV
Sbjct: 16676 GEIRDAAIIDVTSSFTS--------------LVLDNVNRYDSGKYTLTLENSSGTKSAFV 16721
Query: 809 RVKAVNAAGASEPKYYSQPILVKEII----EPPKIRIPRHLKQTYIRRVGEAVNLVIPFQ 864
V+ ++ S P + K+ + EPP + +K + +
Sbjct: 16722 TVRVLDTP--SPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEK------------ 16767
Query: 865 GKPRPELTWKKDGAEID---KNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVET 921
E T K A + KN I + + R + G + +T
Sbjct: 16768 ----REATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYG-------IGLPAQT 16816
Query: 922 ASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV 981
A I++ + P PP + ++DV +V+L+WT P+ DG + I Y ++ K S +W +
Sbjct: 16817 AD-PIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKW-SE 16874
Query: 982 IEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDF 1041
A IT L G EY FRV + N G S+ ++ ++A+D I +
Sbjct: 16875 CARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVP--IVAKDLVIEPD------ 16926
Query: 1042 DFSEAPMFTQPLVNTYAI-AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQG 1100
+P ++Y++ G + + + G PKP ITW K+ + + R + +
Sbjct: 16927 --------VKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLD 16978
Query: 1101 VCTLEIRKPSPYDGGTYCCKAVNDLG--TVEIE 1131
+ TL I++ DGG Y N +G T IE
Sbjct: 16979 LTTLSIKETHKDDGGQYGITVANVVGQKTASIE 17011
Score = 115 bits (287), Expect = 3e-25
Identities = 101/370 (27%), Positives = 158/370 (42%), Gaps = 34/370 (9%)
Query: 266 KGGRVRFVVELAD-----------------PKLEVKWYKNGQEIRPSTKYIFEHKGCQRI 308
+G V FV EL D +E KWY N E++ + KY + ++
Sbjct: 2217 EGAVVEFVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQN 2276
Query: 309 LFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSED 368
L + + D EY +K + +L ++ PI + + L D G+ V+LE +VS +
Sbjct: 2277 LTVKDVTKEDQGEYSFVIDGKKTTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLE 2336
Query: 369 DANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSV 428
W K+G+E+ P R I ++ + H+L+IE TK DA YS S V
Sbjct: 2337 SVEGVWMKDGQEV--QPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRV 2394
Query: 429 DLKPLKILTPLTDQTVNLGKEICLKCEIS--ENIPGKWTKNGLPVQESDRLKVVHKGRIH 486
+ + ++TPL D V G + L+C++S + KW N ++ DR++ + KG
Sbjct: 2395 SVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQ 2454
Query: 487 KLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLE 546
+LVI DEG Y V I I+ GL D T T +E
Sbjct: 2455 RLVINRTHASDEGPYKLIVGRVETNCNLSVEKIK----IIRGL-RDLTCTETQNVVFEVE 2509
Query: 547 IPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG 606
+ SG +W+ DK I + S + + E++ L + +DD G Y AG
Sbjct: 2510 LSHSG---IDVLWNFKDKEI-KPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTF----YAG 2561
Query: 607 EAHASIKVKV 616
E S K+ V
Sbjct: 2562 ENMTSGKLTV 2571
Score = 111 bits (278), Expect = 3e-24
Identities = 96/369 (26%), Positives = 166/369 (44%), Gaps = 22/369 (5%)
Query: 269 RVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGD 328
R F E+++P + V+W K+ QE++ + + + + L I + +M+D +Y V AG
Sbjct: 3028 RAMFECEVSEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGG 3087
Query: 329 EKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSR 388
+ +LFV + + ++ +R +E EV+EDD + W+K+G EI + R
Sbjct: 3088 NVSTAKLFVEGRDVRIRSIKKEVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQER 3147
Query: 389 YRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDL-KPLKILTPLTDQTVNLG 447
++ VE + H + I ++DA EY+ + +SS L V+ +P ++L L TV G
Sbjct: 3148 HKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSG 3207
Query: 448 KEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF-A 504
K IS K W K + + K +H G+ + L++ A ED Y A
Sbjct: 3208 KPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEA 3267
Query: 505 PDAYNVTLPAKVHVIDPPKIILDGLD-----------ADNTVTVIAGNKLRLEIPISGEP 553
+ Y V + ++ P+++ + +TVT G R + +SG
Sbjct: 3268 KNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVT-SEGQPARFQCRVSG-T 3325
Query: 554 PPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGE----AH 609
K W DK I + S R + D+ L I A +D G Y N G+ A+
Sbjct: 3326 DLKVSWYSKDKKI-KPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTAN 3384
Query: 610 ASIKVKVVD 618
S++V+ +D
Sbjct: 3385 LSLEVQALD 3393
Score = 110 bits (276), Expect = 6e-24
Identities = 178/830 (21%), Positives = 319/830 (38%), Gaps = 108/830 (13%)
Query: 352 TAYCGERVELECEVS-EDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADA 410
T G + L+ V + + + W K +E+ K ++ GK+ +I+ ++D+
Sbjct: 22753 TIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEK--VSLQYTGKRATAVIKFCDRSDS 22810
Query: 411 AEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIP-----GKWT 465
+Y++ + +SV +K L P TV+ + KC ++ ++P + T
Sbjct: 22811 GKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTVSRVTQE--KCTLAWSLPQEDGGAEIT 22868
Query: 466 KNGLPVQESDRLK-VVHKGRIHKLVIANALTEDEGDYVF---APDAYNVTLPAKVH---- 517
+ +E+ RL V+ +G L +Y+F A + Y +P +
Sbjct: 22869 HYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVA 22928
Query: 518 ----VIDPPKIILDGLDADNTVTVI--------AGNKLRLEIPISGEPPPKAMWSRGDKA 565
I P I + + +I GN++ + + W+R +K
Sbjct: 22929 RNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYL-VDKREKKSLRWTRVNKD 22987
Query: 566 IMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDF-PDPPV 624
+ R++ S + + + +G +E EA I + + P PP
Sbjct: 22988 YVVYDTRLKVTSLMEGCDYQFRVTAVNAAG------NSEPSEASNFISCREPSYTPGPPS 23041
Query: 625 APTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLC-KETTFEPKK 683
AP V + + W P YDGG+ I+GY +E ++K + +W R++ + + T F
Sbjct: 23042 APRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPD 23101
Query: 684 MIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDH 743
+ G Y R+ AVN G+S+ S P+ P L D + T VT+R
Sbjct: 23102 LKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKT-VTIRAGASLR 23160
Query: 744 --IGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLP 801
+ +G V+ + +G A ++ + +Y L IV + D K+TI
Sbjct: 23161 LMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSL----LIVDKVNRYDAGKYTI---- 23212
Query: 802 TDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEP---PKIRIPRHLKQTY-----IRRV 853
+A N +G S +LVK P P +++ + + I +
Sbjct: 23213 ---------EAENQSGKK-----SATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTI 23258
Query: 854 --GEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDL 911
G VN I + + +K + K I T+ + R + G
Sbjct: 23259 DGGAPVNNYI-VEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYG---- 23313
Query: 912 QVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKA 971
+ + ET+ + + + P P +++ DV V L W P DG + +TGY ++
Sbjct: 23314 ---IGEPCETSDA-VLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEAC 23369
Query: 972 DKKSMEWF-------TVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESA 1024
+ W TV+EH T+T L G +Y FR+ ++N G+SE +A
Sbjct: 23370 KAGTERWMKVVTLKPTVLEH------TVTSLNEGEQYLFRIRAQNEKGVSEPRETV--TA 23421
Query: 1025 VIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNK 1084
V +D ++ D S T P + AG L + G P P +W
Sbjct: 23422 VTVQDLRVLPT-----IDLS-----TMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAG 23471
Query: 1085 VAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKL 1134
+ + R + ++ V L IR+ + D G Y + N GT K+
Sbjct: 23472 SKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKV 23521
Score = 108 bits (270), Expect = 3e-23
Identities = 103/437 (23%), Positives = 169/437 (38%), Gaps = 53/437 (12%)
Query: 719 SPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLP 778
SP L D + +V + WRPP G A + GY+LE ++P
Sbjct: 23925 SPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILE------------------RREVP 23966
Query: 779 AEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPK 838
W + + T + GL + + RV A N G S+P +P+ K + PP+
Sbjct: 23967 KAAWYTIDSR-VRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPE 24025
Query: 839 IRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQIN----IRNSETD- 893
P + +V+L +P+ + + G I++ + + +R+++T
Sbjct: 24026 ---PPSNPPEVLDVTKSSVSLS---WSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQI 24079
Query: 894 TIIFIRKAERSHSGKYDLQVKVDKFV---ETASIDIQII-----DRPGPPQIVKIEDVWG 945
T +Y ++ V ET+ ++ D+P P ++I +
Sbjct: 24080 TTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISK 24139
Query: 946 ENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF-TVIEHYHRTSATITELVIGNEYYFR 1004
++V L W P+ DG I GY ++ W + E TI L+ EY FR
Sbjct: 24140 DSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFR 24199
Query: 1005 VFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNA 1064
VF+EN GLS G EAP + + + G A
Sbjct: 24200 VFAENETGLSRPRRTAMSIKTKLTSG--------------EAPGIRKEMKDVTTKLGEAA 24245
Query: 1065 TLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVND 1124
L+C + G P P I W + ++ +Y+M S+ TL + D G Y C A N+
Sbjct: 24246 QLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNE 24305
Query: 1125 LGTVEIECKLEVKVIAQ 1141
+G VE KL ++ Q
Sbjct: 24306 VGEVETSSKLLLQATPQ 24322
Score = 107 bits (268), Expect = 5e-23
Identities = 123/468 (26%), Positives = 198/468 (42%), Gaps = 56/468 (11%)
Query: 196 RREVKQQEEE---PQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSA 252
R + K++ EE + EL K YE++ + +L K + EEKK+
Sbjct: 1952 RSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRK----TKDELLHWTKELTEEEKKAL 2007
Query: 253 AF-AKILDPAYQVDK-----------------------GGRVRFVVELAD-PKLEVKWYK 287
A KI P ++ DK G F V + P E +WYK
Sbjct: 2008 AEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYK 2067
Query: 288 NGQEIRPSTK---YIFEHKGCQRILFINNCQMTDDSEYYV----TAGDEKCSTELFVREP 340
NG +I S + Y E C+ L I + D + V AG+ L V+
Sbjct: 2068 NGVKIERSDRIYWYWPEDNVCE--LVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAK 2125
Query: 341 PIMV-TKQLEDTTAYCGERV-ELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKH 398
++ T++L+D A + + ECE SE VKW+K+G E+ G K YR+ + K H
Sbjct: 2126 QLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGDK--YRMHSDRKVH 2183
Query: 399 ILIIEGATKADAAEYS---VMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCE 455
L I +DA +YS V +++AKL V+ ++ + L D V L+C
Sbjct: 2184 FLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGELECI 2243
Query: 456 IS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPA 514
+S ENI GKW N + ++ + + + + L + + ED+G+Y F D T
Sbjct: 2244 VSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTT--C 2301
Query: 515 KVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIR 574
K+ + P IL GL V G+ ++LE+ +S E + +W + D ++ S R+
Sbjct: 2302 KLKMKPRPIAILQGLSDQK---VCEGDIVQLEVKVSLE-SVEGVWMK-DGQEVQPSDRVH 2356
Query: 575 TESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDP 622
S L+I+ ++D+G Y + + V VD P
Sbjct: 2357 IVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDVITP 2404
Score = 107 bits (266), Expect = 8e-23
Identities = 171/808 (21%), Positives = 305/808 (37%), Gaps = 106/808 (13%)
Query: 356 GERVELECEVSEDDA-NVKWFKNGEEIIPGPKSRYRIRVEGKKHI--LIIEGATKADAAE 412
G V+L +S A ++W+K+ +E+ ++ + VE + ++I+ A + ++
Sbjct: 20582 GTSVKLRAGISGKPAPTIEWYKDDKEL----QTNALVCVENTTDLASILIKDADRLNSGC 20637
Query: 413 YSVMTTGGQSSAKLSVDL----KPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNG 468
Y + SA ++ + KP P+ +TV K L +++ K T
Sbjct: 20638 YELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYI 20697
Query: 469 LPVQESDRLK-VVHKGRIHKLVIANALTEDEGDYVF---APDAYNVTLPAKVH-VIDPPK 523
+ +E+ R+ + + + +I +Y+F A + Y + P + V+
Sbjct: 20698 VEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNA 20757
Query: 524 IILDGLDADNTVTVIAGNKLRL----EIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYP 579
+ G VT I N + + I G + DK + G ++ E+
Sbjct: 20758 FVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSL-GWFKVLKETIR 20816
Query: 580 DSSTLVIDIAERDDSGVYHINLKNEAGE---AHASIKVKVVDFPDPPVAPTVTEVGDDW- 635
D+ V + E D Y + N AG+ + S K D DPP P + D
Sbjct: 20817 DTRQKVTGLTENSDYQ-YRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTK 20875
Query: 636 --CIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNF-DLCKETTFEPKKMIEGVAYEV 692
+ W P YDGGS + GY +E ++ + W ++ + T + + GV Y
Sbjct: 20876 SSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYF 20935
Query: 693 RIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGY 752
R+ AVN G +P + P + P + D V +R I AG D
Sbjct: 20936 RVSAVNCAGQGEPIEMNEPVQAKDILEAPEI-------DLDVALR---TSVIAKAGEDVQ 20985
Query: 753 VLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKA 812
VL F+G P W K+L +++I TD+ + +
Sbjct: 20986 VL-IPFKGRPP--------------PTVTWRKDEKNLGSDARYSIEN--TDSSSLLTIPQ 21028
Query: 813 VN-----------AAGASEPKYYSQPILVKEIIEP---PKIRIPRHLKQTYIRRVGE--- 855
V G EPK S + VK + P K+++ +H+ + + + +
Sbjct: 21029 VTRNDTGKYILTIENGVGEPK--SSTVSVKVLDTPAACQKLQV-KHVSRGTVTLLWDPPL 21085
Query: 856 ------AVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKY 909
+N VI + + + TW + + + T F R + G
Sbjct: 21086 IDGGSPIINYVI--EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIG-- 21141
Query: 910 DLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQ 969
+ + ET ++ + P P + + ++D +V L+WT P DG + IT Y ++
Sbjct: 21142 -----IGEPCETTE-PVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVE 21195
Query: 970 KADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARD 1029
+ K W + +++L + FRVF++N GLS+ T+
Sbjct: 21196 RKGKGEQTW-SHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTI---------- 21244
Query: 1030 GKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVD 1089
G I V E E + P G+N L +G PKP I+W+K+ + + +
Sbjct: 21245 GPI---TVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKE 21301
Query: 1090 DPRYRMFSNQGVCTLEIRKPSPYDGGTY 1117
R + TL I+ GG Y
Sbjct: 21302 SEFVRFSKTENKITLSIKNAKKEHGGKY 21329
Score = 106 bits (265), Expect = 1e-22
Identities = 117/456 (25%), Positives = 185/456 (40%), Gaps = 83/456 (18%)
Query: 597 YHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFI 656
Y +N + + AS + + D P P VT+V + W PAYDGGS ++GY I
Sbjct: 22611 YALNAAGVSKASEASRPIMAQNPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYII 22670
Query: 657 ERK---KKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIG-ISKPSMPSRPF 712
ERK + RW++ N+ + + F + EG YE R+ A NA G ISK S + P
Sbjct: 22671 ERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPV 22730
Query: 713 VPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGE 772
+PP + VT+R AG D VL+ G K G+
Sbjct: 22731 TCRDEYAPPKAELDARLHGDLVTIR---------AGSD-LVLDAAVGGKPEPKIIWTKGD 22780
Query: 773 AAYDL----------PAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPK 822
DL ++ D D K+T+T NA+G
Sbjct: 22781 KELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLT-------------VKNASGTK--- 22824
Query: 823 YYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTW----KKDGA 878
+ ++VK + P G L + + + L W + GA
Sbjct: 22825 --AVSVMVKVLDSP-----------------GPCGKLTVSRVTQEKCTLAWSLPQEDGGA 22865
Query: 879 EI--------DKNQIN--IRNSETDTIIFIRKAERSHSGKYDLQVK-VDKFVETASIDIQ 927
EI + +++N I E T+ ++ + +Y +V+ V+K+ ++ +
Sbjct: 22866 EITHYIVERRETSRLNWVIVEGECPTLSYV-VTRLIKNNEYIFRVRAVNKYGPGVPVESE 22924
Query: 928 -IIDR-----PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV 981
I+ R P PP I + E++ + WT P+ DG I+ Y + K +KKS+ W V
Sbjct: 22925 PIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRV 22984
Query: 982 IEHY--HRTSATITELVIGNEYYFRVFSENMCGLSE 1015
+ Y + T +T L+ G +Y FRV + N G SE
Sbjct: 22985 NKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSE 23020
Score = 106 bits (264), Expect = 1e-22
Identities = 128/545 (23%), Positives = 211/545 (38%), Gaps = 64/545 (11%)
Query: 620 PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTF 679
P PP P V + + W+PPA DGGSPI GY +E +++ ++ W R+N TT
Sbjct: 9400 PGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTC 9459
Query: 680 E--PKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMR 737
E + E Y R+ AVN G S+PS + + P + +D + +
Sbjct: 9460 ECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVF-IDIGAQDCLVCK 9518
Query: 738 WRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTI 797
I A + +E AK++ ++G +D+P + A + + + I
Sbjct: 9519 AGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDG--VHDIPED----AQLETAENSSVII 9572
Query: 798 TGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAV 857
+P + ++ A + K + + V ++ PPK LK + I R +
Sbjct: 9573 --IPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPK-----DLKVSDITRGSCRL 9625
Query: 858 NLVIP------------FQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIR-KAERS 904
+ +P + + W K + + + ++ F R +AE
Sbjct: 9626 SWKMPDDDGGDRIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAEN- 9684
Query: 905 HSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAIT 964
++ + V+ T + D I P PP +KI + V L+W PPK+DG + +T
Sbjct: 9685 ---RFGIGPPVETIQRTTARDP--IYPPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVT 9739
Query: 965 GYTIQ-----KADKKSMEWFTVIEH-YHRTSATITELVIGNEYYFRVFSENMCGLSEDAT 1018
Y ++ K W + T+ +LV G EY FRV + N G+S+ +
Sbjct: 9740 HYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPSA 9799
Query: 1019 MTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKI 1078
D P + +F E G N + ++G P P +
Sbjct: 9800 TVGPCDCQRPD----MPPSIDLKEFMEVE------------EGTNVNIVAKIKGVPFPTL 9843
Query: 1079 TWMK-------NKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIE 1131
TW K NK ++ D CTL I + D G Y AVN+LGT E
Sbjct: 9844 TWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKE 9903
Query: 1132 CKLEV 1136
+L V
Sbjct: 9904 MRLNV 9908
Score = 105 bits (263), Expect = 2e-22
Identities = 101/375 (26%), Positives = 158/375 (42%), Gaps = 21/375 (5%)
Query: 263 QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 322
+V +G V+ V+++ +E W K+GQE++PS + +L I + D Y
Sbjct: 2320 KVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNY 2379
Query: 323 YVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDD-ANVKWFKNGEEI 381
T ST V + V L+D G + LEC+VS D +VKW+ N E+I
Sbjct: 2380 SFTIPALGLSTSGRVSVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQI 2439
Query: 382 IPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTD 441
P R + V+G K L+I +D Y ++ +++ LSV+ +KI+ L D
Sbjct: 2440 --KPDDRVQAIVKGTKQRLVINRTHASDEGPYKLIVGRVETNCNLSVE--KIKIIRGLRD 2495
Query: 442 QTVNLGKEICLKCEISEN-IPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGD 500
T + + + E+S + I W ++ S + K+ G+I+KL + N + +DEG
Sbjct: 2496 LTCTETQNVVFEVELSHSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGK 2555
Query: 501 YVF--APDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAM 558
Y F + + L I P D TV E+ P K
Sbjct: 2556 YTFYAGENMTSGKLTVAGGAISKPL-------TDQTVAESQEAVFECEV---ANPDSKGE 2605
Query: 559 WSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVD 618
W R K + + IR+ES L+I + DD G Y K + A +KV+ V
Sbjct: 2606 WLRDGKH-LPLTNNIRSESDGHKRRLIIAATKLDDIGEY--TYKVATSKTSAKLKVEAVK 2662
Query: 619 FPDPPVAPTVTEVGD 633
TVTE D
Sbjct: 2663 IKKTLKNLTVTETQD 2677
Score = 103 bits (258), Expect = 7e-22
Identities = 110/456 (24%), Positives = 174/456 (38%), Gaps = 80/456 (17%)
Query: 702 ISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGS 761
+ KP +P+ P + D VT +T++W PP G + + Y+LE
Sbjct: 13768 VGKPGIPTGP------------IKFDEVTAEAMTLKWAPPKDDGGSEITNYILE------ 13809
Query: 762 TSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGA--- 818
K+ N + W+ + KT F +T L + RV A N G
Sbjct: 13810 ---KRDSVNNK---------WVTC-ASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEG 13856
Query: 819 --SEPKYYSQPILVKEIIEPPKIRIPRH----LKQTYIRRVGEAVNLVIPFQGKPRPELT 872
SEP P V + PP I RH L T ++ G + + K R L
Sbjct: 13857 LKSEPIVARHPFDVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLL 13916
Query: 873 WKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETAS--------I 924
WK+ +K I +R+ + + + +Y+ +V +
Sbjct: 13917 WKR----ANKTPIRMRDFKVTGL--------TEGLEYEFRVMAINLAGVGKPSLPSEPVV 13964
Query: 925 DIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIE- 983
+ ID PG P+++ I +V L WT PK DG +TGY ++K D S W
Sbjct: 13965 ALDPIDPPGKPEVINITR---NSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHV 14021
Query: 984 HYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDF 1043
+ + T+T+LV G +Y FR+ ++N G + + E+ +I +D ++
Sbjct: 14022 NVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTET-IICKD------------EY 14068
Query: 1044 SEAPMFTQPLVNTYAI--AGYNATLNC-SVRGNPKPKITWMKNKVAIVDDPRYRMFSNQG 1100
+ P + AG LN S+ G P PK +W K I ++ S
Sbjct: 14069 EAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPT 14128
Query: 1101 VCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
L I+ + D G Y A N GT K+ V
Sbjct: 14129 SSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTV 14164
Score = 102 bits (255), Expect = 2e-21
Identities = 103/389 (26%), Positives = 171/389 (43%), Gaps = 15/389 (3%)
Query: 248 EKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHK-GCQ 306
E+ F K L+ V KG + EL + + +V W K+G+ + I G
Sbjct: 4903 EELPVRFVKTLEEEVTVVKGQPLYLSCEL-NKERDVVWRKDGKIVVEKPGRIVPGVIGLM 4961
Query: 307 RILFINNCQMTDDSEYYVT---AGDEKCSTELFVREP-PIMVTKQLEDTTAYCGERVELE 362
R L IN+ TD Y VT A + +CS+ + V E + K + D
Sbjct: 4962 RALTINDADDTDAGTYTVTVENANNLECSSCVKVVEVIRDWLVKPIRDQHVKPKGTAIFA 5021
Query: 363 CEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQS 422
C++++D N+KWFK +EI P + I +G L I+ A D AEY+V G +
Sbjct: 5022 CDIAKDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGKRY 5081
Query: 423 SAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVH 481
AKL++ + +++L P+ D T+ + EISE +IPG+W G ++ S ++
Sbjct: 5082 PAKLTLGEREVELLKPIEDVTIYEKESASFDAEISEADIPGQWKLKGELLRPSPTCEIKA 5141
Query: 482 KGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGN 541
+G L + + G+ ++ A N A ++ +I LD VTV
Sbjct: 5142 EGGKRFLTLHKVKLDQAGEVLY--QALNAITTA---ILTVKEIELDFAVPLKDVTVPERR 5196
Query: 542 KLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINL 601
+ R E ++ E +WS+G I++ S + + LVI+ ++ DD GVY +
Sbjct: 5197 QARFECVLTRE--ANVIWSKGPD-IIKSSDKFDIIADGKKHILVINDSQFDDEGVYTAEV 5253
Query: 602 KNEAGEAHASIKVKVVDFPDPPVAPTVTE 630
+ + A + + F P TV E
Sbjct: 5254 EGKKTSARLFVTGIRLKFMSPLEDQTVKE 5282
Score = 102 bits (254), Expect = 2e-21
Identities = 85/281 (30%), Positives = 121/281 (43%), Gaps = 16/281 (5%)
Query: 283 VKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPI 342
V W K I+ S K+ G + IL IN+ Q D+ Y +K S LFV +
Sbjct: 5210 VIWSKGPDIIKSSDKFDIIADGKKHILVINDSQFDDEGVYTAEVEGKKTSARLFVTGIRL 5269
Query: 343 MVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILII 402
LED T GE CE+S + +V WFKN ++ I EGK H L +
Sbjct: 5270 KFMSPLEDQTVKEGETATFVCELSHEKMHVVWFKNDAKL--HTSRTVLISSEGKTHKLEM 5327
Query: 403 EGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPG 462
+ T D ++ S+A+L V L D+T EI LKCE+S+++P
Sbjct: 5328 KEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSKDVPV 5387
Query: 463 KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV----FAPDAYNVTLPAKVHV 518
KW K+G + S + + G L I A +D+G+YV NVT+ A++
Sbjct: 5388 KWFKDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIK 5447
Query: 519 IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMW 559
++ P L G V V G EI +S EP W
Sbjct: 5448 VEKP---LYG------VEVFVGETAHFEIELS-EPDVHGQW 5478
Score = 102 bits (254), Expect = 2e-21
Identities = 179/762 (23%), Positives = 289/762 (37%), Gaps = 135/762 (17%)
Query: 340 PPIMVTKQLEDTTAYCGERVELECEV-SEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKH 398
P I++ +Q+ T G+++ +E V + KW K +E++ S +
Sbjct: 12595 PKILMPEQI---TIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTS--SHLAVHKADSSS 12649
Query: 399 ILIIEGATKADAAEYSVMT--TGGQSSAKLSV--------------------DLKPLKIL 436
ILII+ T+ D+ YS+ + G + K+ V D L
Sbjct: 12650 ILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWH 12709
Query: 437 TPLTDQTVNLGKEICLKCEISENIPGKW-TKNGLPVQESDRLKVVHKGRIH--------K 487
PL D N+ I KC++S G W T + S R+ + G+ + +
Sbjct: 12710 IPLEDGGSNITNYIVEKCDVSR---GDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENR 12766
Query: 488 LVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIIL--DGLDADNTVTVIAGNKLRL 545
I+ LT + F + A+V ++ I + D D+D +I
Sbjct: 12767 FGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIG------ 12820
Query: 546 EIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEA 605
I + +W + + + +R+ YP + +++ E + I N+A
Sbjct: 12821 -YLIERKERNSLLWVKANDTL------VRSTEYPCAG--LVEGLEYS----FRIYALNKA 12867
Query: 606 GEAHASIKVKVVDFP---DPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQ 662
G + S + V DPP P V +V + W P +DGGS I+GYF+E K
Sbjct: 12868 GSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLP 12927
Query: 663 SSRWMRLNF--DLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSP 720
+W+R N + + + E Y+ R A A+ IS PS PS P LA P
Sbjct: 12928 GDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVP 12987
Query: 721 P---------TLLTVDSVT----DTTV------TMRWRPPDHIGAAGLDGYVLEYCFEGS 761
P +LLTV + T D TV T+ W+ DG +L+ EG
Sbjct: 12988 PRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKK---------DGTLLKPA-EGI 13037
Query: 762 TSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEP 821
A Q + E + V KD D T T +++K ++ G
Sbjct: 13038 KMAMQRNL-------CTLELFSVNRKDSGDYT-ITAENSSGSKSATIKLKVLDKPGPPAS 13089
Query: 822 ----KYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVG-EAVNLVIPFQGKPRPELTWKKD 876
K YS ++ EPP + G E N ++ + RP W +
Sbjct: 13090 VKINKMYSDRAMLSW--EPP------------LEDGGSEITNYIVDKRETSRPN--WAQV 13133
Query: 877 GAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ 936
A + ++ R + G D F E A I D PG
Sbjct: 13134 SATVPITSCSVEKLIEGHEYQFRICAENKYGVGD-----PVFTEPA-IAKNPYDPPGRCD 13187
Query: 937 IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATI--TE 994
I ++ +++ ++W PP DDG + ITGY ++K + +++ W T + T+ T
Sbjct: 13188 PPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNW-TKVNRKPIIERTLKATG 13246
Query: 995 LVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNP 1036
L G EY FRV + N G + + +K A ARD + P
Sbjct: 13247 LQEGTEYEFRVTAINKAGPGKPSDASK--AAYARDPQYPPGP 13286
Score = 98.6 bits (244), Expect = 3e-20
Identities = 93/361 (25%), Positives = 149/361 (41%), Gaps = 12/361 (3%)
Query: 271 RFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEK 330
+F E++ +W K QEI ++ G + + I + D+++Y A D+
Sbjct: 5553 KFECEVSREPKTFRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKH 5612
Query: 331 CSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYR 390
S +L + + L+D TA E E+S D+ VKWFKN + +
Sbjct: 5613 TSGKLIIEGIRLKFLTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRL--HTTRSVS 5670
Query: 391 IRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEI 450
++ EGK H + + + D ++ V G S AKL+V L D T E+
Sbjct: 5671 MQDEGKTHSITFKDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEV 5730
Query: 451 CLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYN 509
L+CEIS+ + P KW K+G ++ S + G+ L++ AL D G Y D
Sbjct: 5731 ILQCEISKADAPVKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTC--DCGT 5788
Query: 510 VTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWS-RGDKAIME 568
K+ + D ++ L ++V V+ R E IS E A W +G+ +
Sbjct: 5789 DKTSGKLDIEDREIKLVRPL---HSVEVMETETARFETEIS-EDDIHANWKLKGEALLQT 5844
Query: 569 GSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTV 628
I+ E S LV+ D +G N AH +K +V+ P TV
Sbjct: 5845 PDCEIKEEGKIHS--LVLHNCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTV 5902
Query: 629 T 629
T
Sbjct: 5903 T 5903
Score = 97.1 bits (240), Expect = 9e-20
Identities = 126/568 (22%), Positives = 206/568 (36%), Gaps = 75/568 (13%)
Query: 597 YHINLKNEAGEAHASIKVKVV---DFPDPPVAPTVTEVGDDW---CIMNWEPPAYDGGSP 650
+ + +NE G S+ + V D +PP PT V D + W P YDGG+P
Sbjct: 12163 FRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAP 12222
Query: 651 ILGYFIERKKKQSSR-----WMRLNFDL-CKETTFEPKKMIEGVAYEVRIFAVNAIGISK 704
I+GY +E + K + W R N F + E YE R+ A N +GI +
Sbjct: 12223 IIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGR 12282
Query: 705 PSMPSRPFVPLAVTSPPTLLTVDSVTDTTVT-----------MRWRPPDHIG--AAGLDG 751
P+ P + PP + S+ + +R RP + G+D
Sbjct: 12283 PAELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDN 12342
Query: 752 YVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGL-PTDAK-IFVR 809
V + Q D A+ ++ N D K+++T + P K +FV
Sbjct: 12343 VVRK---------GQVDLVDTMAF------LVIPNSTRDDSGKYSLTLVNPAGEKAVFVN 12387
Query: 810 VKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRP 869
V+ ++ G P+ ++ + K H+ G + + +
Sbjct: 12388 VRVLDTPG---------PVSDLKVSDVTKTSC--HVSWAPPENDGGSQVTHYIVEKREAD 12436
Query: 870 ELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQII 929
TW E+ K ++ N + R + G V V + +
Sbjct: 12437 RKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGP-----GVPTDVPKPVLASDPL 12491
Query: 930 DRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGY-TIQKADKKSMEWFTVIEHYHRT 988
P PP+ +++ ++ + L W PP DG A I GY T + +++ + +T
Sbjct: 12492 SEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDL 12551
Query: 989 SATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPM 1048
S +T L G +Y FRV + N G+S + R+ + VYE + P
Sbjct: 12552 SLVVTGLKEGKKYKFRVAARNAVGVS-----------LPREAE----GVYEAKEQLLPPK 12596
Query: 1049 FTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRK 1108
P T AG + V G P P W K + +V + L I+
Sbjct: 12597 ILMPEQITIK-AGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKD 12655
Query: 1109 PSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
+ D G Y A N GT + K+ V
Sbjct: 12656 VTRKDSGYYSLTAENSSGTDTQKIKVVV 12683
Score = 94.4 bits (233), Expect = 6e-19
Identities = 147/655 (22%), Positives = 260/655 (39%), Gaps = 108/655 (16%)
Query: 20 EEPSKEKEAGTTPAKDWTLVETPPGEEQAKQNANSQLSILFIEKPQGGTVKVGEDITFIA 79
E+ SK E + K T E +A + +S+ I + Q TV F
Sbjct: 26511 EKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVI--VTGLQDTTVSSDSVAKFAV 26568
Query: 80 KVKAEDLLRKPTIKWFK--------GKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIK 131
K E +PT W K GK+ K G L++ +T S +YT ++
Sbjct: 26569 KATGEP---RPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVK--- 26622
Query: 132 AKDNFAGNYR--CEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSGEGQEDAGELD 189
N AG+ C++T K D+ + + +++ TP K++ +E + +
Sbjct: 26623 ---NSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQ-------KKAVVQEEISQKAL 26672
Query: 190 FSGLLKRREVKQQE------EEPQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKRLKR 243
S +K E K QE E +V + E +K + + EK IT
Sbjct: 26673 RSEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKTS-------- 26724
Query: 244 MRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHK 303
EE ++ A K +++G R+ +A +VKW NG E+ S +Y +
Sbjct: 26725 QASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGAT-DVKWVLNGVELTNSEEYRYGVS 26783
Query: 304 GCQRILFINNCQMTDDSEYYVTA----GDEKCSTELFVREPPIMVTKQLEDTTAYC---- 355
G + L I D+ + G KC +L ++K+L D A+
Sbjct: 26784 GSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDL-------TLSKELSDAPAFISQPR 26836
Query: 356 ------GERVELECEVS-EDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKA 408
G+ V CE+S E ++WFKN I S I + L I A+ +
Sbjct: 26837 SQNINEGQNVLFTCEISGEPSPEIEWFKNNLPI--SISSNVSISRSRNVYSLEIRNASVS 26894
Query: 409 DAAEYSVMTTG--GQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTK 466
D+ +Y++ GQ SA S+ ++ PL ++ +E+ L+ ++ G ++
Sbjct: 26895 DSGKYTIKAKNFRGQCSATASL------MVLPLVEEP---SREVVLRTSGDTSLQGSFSS 26945
Query: 467 NGLPVQESDR-----------LKVVHKGRIHKLVIANALTEDEGDYVFAPDAY----NVT 511
+ + S + + + + + + + E + ++ N+T
Sbjct: 26946 QSVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMT 27005
Query: 512 ---------LPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRG 562
L A + I PPKI + L +D +++ G L + +GEP P+ WS G
Sbjct: 27006 QLESSTSKMLKAGIRGI-PPKI--EALPSD--ISIDEGKVLTVACAFTGEPTPEVTWSCG 27060
Query: 563 DKAI-MEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKV 616
+ I + GR E+ D +TL+I ++ D G+Y ++L NE G A++ + +
Sbjct: 27061 GRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 27115
Score = 94.0 bits (232), Expect = 7e-19
Identities = 93/416 (22%), Positives = 158/416 (37%), Gaps = 58/416 (13%)
Query: 728 SVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANK 787
+VT +T+ WRPP G A + Y++E E + + +E
Sbjct: 20672 TVTAEKITLLWRPPADDGGAKITHYIVE-----------KRETSRVVWSMVSEH------ 20714
Query: 788 DLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQ 847
+++ T T + + RV+AVN G EP + + P IP K
Sbjct: 20715 --LEECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKI 20772
Query: 848 T-------YIRRVGEAVNLVIPF--QGKPRPELTW---KKDGAEIDKNQINIRNSETDTI 895
T + R + + + + + + + + L W K+ + ++ +D
Sbjct: 20773 TKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQ 20832
Query: 896 IFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPP 955
+ + G + + +F + A ID PGPP ++I D ++ L W+ P
Sbjct: 20833 YRVCAVNAAGQGPFS---EPSEFYKAADP----IDPPGPPAKIRIADSTKSSITLGWSKP 20885
Query: 956 KDDGNAAITGYTIQKADKKSMEWFTVIE--HYHRTSATITELVIGNEYYFRVFSENMCGL 1013
DG +A+TGY ++ + EW TV T ++ L G YYFRV + N G
Sbjct: 20886 VYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQ 20945
Query: 1014 SEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLV---NTYAIAGYNATLNCSV 1070
E M N + D EAP + + A AG + +
Sbjct: 20946 GEPIEM---------------NEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPF 20990
Query: 1071 RGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLG 1126
+G P P +TW K++ + D RY + + L I + + D G Y N +G
Sbjct: 20991 KGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVG 21046
Score = 92.0 bits (227), Expect = 3e-18
Identities = 69/216 (31%), Positives = 100/216 (46%), Gaps = 18/216 (8%)
Query: 930 DRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV-IEHYHRT 988
++PG P I V ++ + W PP DG A I Y ++K +KK +W +V E T
Sbjct: 24518 EKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRET 24577
Query: 989 SATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFS-EAP 1047
++ L+ G EY FRV EN+ G SE + +++ P+ D +AP
Sbjct: 24578 VFSVKNLIEGLEYEFRVKCENLGGESEWSEISE--------------PITPKSDVPIQAP 24623
Query: 1048 MFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMK-NKVAIVDDPRYRMFS-NQGVCTLE 1105
F + L N NATL C V G+PKP + W + K I D +YR+ G L
Sbjct: 24624 HFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLI 24683
Query: 1106 IRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVIAQ 1141
I + D Y +A N G+V LEV+V A+
Sbjct: 24684 IASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAK 24719
Score = 89.4 bits (220), Expect = 2e-17
Identities = 99/438 (22%), Positives = 170/438 (38%), Gaps = 59/438 (13%)
Query: 600 NLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERK 659
N+ ++ + S + +D DPP P + + W P Y GG I Y +E++
Sbjct: 15032 NMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKR 15091
Query: 660 KKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIG-ISKPSMPSRPFVPLAVT 718
+ RW++ NF E F + E AYE R+ A NA G IS PS PS
Sbjct: 15092 DLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDV 15151
Query: 719 SPPTLLTVDSVTDTTVTMRWRPPDHIGA--AGLDGYVLEYCFEGSTSAKQSDENGEAAYD 776
P + VD TV ++ + A +G +E+ +G + G A +
Sbjct: 15152 EAPK-IKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDG------KELEGTAKLE 15204
Query: 777 LPAEDWI--VANKDLI--DKTKFTITGLPTD--AKIFVRVKAVNAAGASEPKYYSQPILV 830
+ D+ + NKD D +T+T AK VK ++ G E P+ V
Sbjct: 15205 IKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPE-----GPLAV 15259
Query: 831 KEIIE--------PPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDK 882
E+ PP + G ++ I Q + L W +E+
Sbjct: 15260 TEVTSEKCVLSWFPP------------LDDGGAKIDHYI-VQKRETSRLAWTNVASEVQV 15306
Query: 883 NQINI-RNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIE 941
++ + + + + IF A + L+ + + P PP+ ++
Sbjct: 15307 TKLKVTKLLKGNEYIFRVMAVNKYGVGEPLE-------SEPVLAVNPYGPPDPPKNPEVT 15359
Query: 942 DVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF-----TVIEHYHRTSATITELV 996
+ +++ + W P DG + I Y +++ DK W T+ + ++ S L
Sbjct: 15360 TITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSG----LT 15415
Query: 997 IGNEYYFRVFSENMCGLS 1014
G+EY FR+ +EN G+S
Sbjct: 15416 EGHEYEFRIMAENAAGIS 15433
Score = 89.0 bits (219), Expect = 2e-17
Identities = 61/198 (30%), Positives = 88/198 (44%), Gaps = 18/198 (9%)
Query: 932 PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSAT 991
P PP+ VK D ++ LTW PPK+DG + I GY +++ + S +W E T
Sbjct: 7283 PDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPVAETKME 7342
Query: 992 ITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAP---M 1048
+T L G Y +RV + N G S+ + T+E + D EAP +
Sbjct: 7343 VTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAV---------------DTQEAPEIFL 7387
Query: 1049 FTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRK 1108
+ L AG L +V G P+PKITW K + + D R + + T+ I
Sbjct: 7388 DVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVD 7447
Query: 1109 PSPYDGGTYCCKAVNDLG 1126
D GTY +AVN G
Sbjct: 7448 SKRSDTGTYIIEAVNVCG 7465
Score = 86.7 bits (213), Expect = 1e-16
Identities = 112/510 (21%), Positives = 197/510 (38%), Gaps = 70/510 (13%)
Query: 648 GSPILGYFIERKKKQSSRWMRLNFDLCKET-TFEPKKMIEGVAYEVRIFAVNAIGISKPS 706
G P+ + R MR N ++ E T K+ + A I A N+ G +K
Sbjct: 20197 GKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAF 20256
Query: 707 MPSRPFVPLAVTSPPT-LLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAK 765
+ V L PPT + + +T+ +VT++W PP + G + + Y+L + TS
Sbjct: 20257 IN---IVVLDRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYIL---LKRETSTA 20310
Query: 766 QSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYS 825
E + +T + L T + R+KA N G S+ S
Sbjct: 20311 VWTEVSAT----------------VARTMMKVMKLTTGEEYQFRIKAENRFGISD-HIDS 20353
Query: 826 QPILVK---EIIEPPKIRIPRHLKQTYI-----RRVGEAVNLVIPF--QGKPRPELTWKK 875
+ VK PP ++ + I V + V+ + + K R + W+K
Sbjct: 20354 ACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQK 20413
Query: 876 DGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETA-----SIDIQIID 930
N++ IR + + S Y+ +V + S + ID
Sbjct: 20414 ------ANKLVIRTTH------FKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAID 20461
Query: 931 RPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV-IEHYHRTS 989
PP+ V+I D+ +V+L+W P DG + ITGY +++ D W + T
Sbjct: 20462 ACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVTETQ 20521
Query: 990 ATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMF 1049
I+ L ++Y FRVF+ N G +++ S V+ P+ D P+
Sbjct: 20522 FIISGLTQNSQYEFRVFARNAVG-----SISNPSEVVG--------PI-TCIDSYGGPVI 20567
Query: 1050 TQPLVNTYAI---AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEI 1106
PL T + AG + L + G P P I W K+ + + + + + ++ I
Sbjct: 20568 DLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILI 20627
Query: 1107 RKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
+ + G Y K N +G+ ++++
Sbjct: 20628 KDADRLNSGCYELKLRNAMGSASATIRVQI 20657
Score = 86.3 bits (212), Expect = 2e-16
Identities = 94/359 (26%), Positives = 158/359 (44%), Gaps = 23/359 (6%)
Query: 285 WYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVT---AGDEKCST-ELFVREP 340
W K+G IR S K+ F G R L I + Q++D EY EK ST +L V E
Sbjct: 4846 WMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEEL 4905
Query: 341 PIMVTKQL-EDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHI 399
P+ K L E+ T G+ + L CE+++ + +V W K+G+ ++ P R V G
Sbjct: 4906 PVRFVKTLEEEVTVVKGQPLYLSCELNK-ERDVVWRKDGKIVVEKP-GRIVPGVIGLMRA 4963
Query: 400 LIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKIL-----TPLTDQTVNLGKEICLKC 454
L I A DA Y+V T ++ + S +K ++++ P+ DQ V C
Sbjct: 4964 LTINDADDTDAGTYTV-TVENANNLECSSCVKVVEVIRDWLVKPIRDQHVKPKGTAIFAC 5022
Query: 455 EISENIPG-KWTK--NGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVT 511
+I+++ P KW K + +P + +D+ +++ G L I NA+ ED +Y A +
Sbjct: 5023 DIAKDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEY--AVEIEGKR 5080
Query: 512 LPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSG 571
PAK+ + + +L ++ VT+ + IS P +G+ ++ S
Sbjct: 5081 YPAKLTLGEREVELLKPIE---DVTIYEKESASFDAEISEADIPGQWKLKGE--LLRPSP 5135
Query: 572 RIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTE 630
++ L + + D +G N A ++K +DF P TV E
Sbjct: 5136 TCEIKAEGGKRFLTLHKVKLDQAGEVLYQALNAITTAILTVKEIELDFAVPLKDVTVPE 5194
Score = 86.3 bits (212), Expect = 2e-16
Identities = 78/292 (26%), Positives = 125/292 (42%), Gaps = 60/292 (20%)
Query: 265 DKGGRVRFV--VELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 322
++GG V++V +E D +V WY +++ S KY ++ IL++ + DD Y
Sbjct: 25275 EEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTY 25334
Query: 323 YVTA----GDEKCSTELFVR---------------------------EPPIMVTKQLEDT 351
G++ ELFV+ E P T L +
Sbjct: 25335 RCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNK 25394
Query: 352 TAYCGERVELECEVS-EDDANVKWFKNGEEIIPGPK-SRYRIRVEGKKHILIIEGATKAD 409
TAY GE V ++ + +V W+K+G++I PG +Y + + L I T D
Sbjct: 25395 TAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDD 25454
Query: 410 AAEYSVMTTG--GQSS--AKLSVDLKPLKILTPLTDQTV-------------NLGKEICL 452
AEY+V+ G+ S AKL+V L P P TD T+ G+ +C
Sbjct: 25455 DAEYTVVARNKYGEDSCKAKLTVTLHP-----PPTDSTLRPMFKRLLANAECQEGQSVCF 25509
Query: 453 KCEISENIPG--KWTKNGLPVQESDRLKVVHKG-RIHKLVIANALTEDEGDY 501
+ +S P KW K+G P+ ++++H+G + L I + L ED G Y
Sbjct: 25510 EIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYY 25561
Score = 85.9 bits (211), Expect = 2e-16
Identities = 115/472 (24%), Positives = 174/472 (36%), Gaps = 92/472 (19%)
Query: 693 RIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGY 752
R AVN + KP P+ P L ++ +T ++ W P G A +D Y
Sbjct: 19566 RSVAVNCKVLDKPGPPAGP------------LEINGLTAEKCSLSWGRPQEDGGADIDYY 19613
Query: 753 VLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKA 812
++E E A W + +L T +T L + RV
Sbjct: 19614 IVE-----------KRETSHLA-------WTICEGEL-QMTSCKVTKLLKGNEYIFRVTG 19654
Query: 813 VNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELT 872
VN G EP + + +K + P L+ T + + E++ L RPE
Sbjct: 19655 VNKYGVGEPL---ESVAIKALDPFTVPSPPTSLEITSVTK--ESMTLCWS-----RPE-- 19702
Query: 873 WKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQI---- 928
G+EI I R E +++ ++R ++ YDL+VK E + ++
Sbjct: 19703 -SDGGSEISGYIIERR--EKNSLRWVRVNKKP---VYDLRVKSTGLREGCEYEYRVYAEN 19756
Query: 929 -------------------IDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQ 969
+ P PP KI D + + W P DG A ITGYT++
Sbjct: 19757 AAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVE 19816
Query: 970 KADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARD 1029
+W T I+ T TI+ L G EY FRV S N G S+ + + D
Sbjct: 19817 YKKSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSS--------D 19868
Query: 1030 GKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVD 1089
+I K E ++ M +V AG + T+ RG P P + W K
Sbjct: 19869 PQIAKEREEEPLFDIDSEMRKTLIVK----AGASFTMTVPFRGRPVPNVLWSKPDT---- 19920
Query: 1090 DPRYRMF--SNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVI 1139
D R R + + +L I + D G Y N L + L VKV+
Sbjct: 19921 DLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASL--TLVVKVL 19970
Score = 85.9 bits (211), Expect = 2e-16
Identities = 128/602 (21%), Positives = 222/602 (36%), Gaps = 112/602 (18%)
Query: 581 SSTLVIDIAERDDSGV--YHINLKNEAGEAH----ASIKVKV------VDFPDPPVAPTV 628
S T I++++ + V + + KNE G + I VK VD D P A
Sbjct: 21210 SKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPITVKELIITPEVDLSDIPGAQVT 21269
Query: 629 TEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKET-TFEPKKMIEG 687
+G + ++ E P P + + + + S ++R + K T + + K G
Sbjct: 21270 VRIGHN---VHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHG 21326
Query: 688 VAYEVRI--------FAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWR 739
Y V + + I + PS P P + D + +V + W
Sbjct: 21327 GKYTVILDNAVCRIAVPITVITLGPPSKPKGP------------IRFDEIKADSVILSWD 21374
Query: 740 PPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITG 799
P+ G + Y +E T+ K + + +T F +
Sbjct: 21375 VPEDNGGGEITCYSIEKRETSQTNWKMVCSS-------------------VARTTFKVPN 21415
Query: 800 LPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNL 859
L DA+ RV+A N G S QP++ I+ + RIP G+ V
Sbjct: 21416 LVKDAEYQFRVRAENRYGVS------QPLVSSIIVAKHQFRIPGP--------PGKPVIY 21461
Query: 860 VIPFQGKPRPELTWKKD----GAEIDKNQINIRNSETDTIIFIRKAERSHSGK------- 908
+ G LTW G+E+ ++ E ++I++ + SG+
Sbjct: 21462 NVTSDGM---SLTWDAPVYDGGSEV--TGFHVEKKERNSILWQKVNTSPISGREYRATGL 21516
Query: 909 -----YDLQVKVDKFVETAS--------IDIQIIDRPGPPQIVKIEDVWGENVALTWTPP 955
Y +V + +S + + +D PG P + DV E + L W PP
Sbjct: 21517 VEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYI---DVTRETITLKWNPP 21573
Query: 956 KDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1015
DG + I GY+I+K T+T L G+ Y FR+ + N G
Sbjct: 21574 LRDGGSKIVGYSIEKRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTIS 21633
Query: 1016 DATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPK 1075
+ + ++ RD + P +F P + L+ +G + + V+G P
Sbjct: 21634 PPSQSS-GIIMTRDENV---PPIVEF----GPEYFDGLIIK---SGESLRIKALVQGRPV 21682
Query: 1076 PKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLE 1135
P++TW K+ V I + G +L +R + G Y +A N G+ + E K++
Sbjct: 21683 PRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVK 21742
Query: 1136 VK 1137
V+
Sbjct: 21743 VQ 21744
Score = 85.5 bits (210), Expect = 3e-16
Identities = 203/971 (20%), Positives = 332/971 (34%), Gaps = 208/971 (21%)
Query: 259 DPAYQVDKGGRVRFVVEL-ADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMT 317
D Y + R + + P V W K + T+ E L + +CQ +
Sbjct: 13684 DLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKS 13743
Query: 318 DDSEYYVT----AGDEKCSTELFVREPPIMVTKQL--EDTTAYC------------GERV 359
D +Y +T AG ++ + + V P + T + ++ TA G +
Sbjct: 13744 DAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEI 13803
Query: 360 ELECEVSEDDANVKWFKNGEEIIPGPKSRYRI-----------RVEGKKHILIIEGATKA 408
D N KW + K+ +R+ RV + + EG
Sbjct: 13804 TNYILEKRDSVNNKWVTCASAV---QKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSE 13860
Query: 409 DAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEIC-LKCEISENIPGKWTK- 466
VD++ + TD G I E E W +
Sbjct: 13861 PIVARHPFDVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRA 13920
Query: 467 NGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIIL 526
N P++ D KV LTE +Y F A N+ K + P + L
Sbjct: 13921 NKTPIRMRD-FKVT------------GLTEGL-EYEFRVMAINLAGVGKPSLPSEPVVAL 13966
Query: 527 DGLDAD----------NTVTVI-------AGNKLRLEIPISGEPPPKAMWSRGDKAIMEG 569
D +D N+VT+I G+KL I + P K+ W + +
Sbjct: 13967 DPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKS-WMKANHV---- 14021
Query: 570 SGRIRTESYPDSSTLVIDIAERDDSGVYH--INLKNEAGEAHA-SIKVKVVDFPDPPVAP 626
+ P+ + V D+ E G Y I KN AG A S + + D AP
Sbjct: 14022 -------NVPECAFTVTDLVE---GGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAP 14071
Query: 627 TVTEVGDDWCIMNWEPPAYDG-----GSPIL--GYFIERKKKQSSRWMRLNFDL----CK 675
T+ +P DG G I+ I K S W + D+
Sbjct: 14072 TIV----------LDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDIT 14121
Query: 676 ETTFEPKKMIEGVAYEVR-------IFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDS 728
+ T P + + Y R I A N G + L V PP + + +
Sbjct: 14122 QITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVK---VTVLDVPGPPGPVEISN 14178
Query: 729 VTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKD 788
V+ T+ W PP G + + Y+LE + TS W V ++D
Sbjct: 14179 VSAEKATLTWTPPLEDGGSPIKSYILE---KRETSRLL---------------WTVVSED 14220
Query: 789 LIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQT 848
I + T L + RV AVN G EP S+P+ + + PP
Sbjct: 14221 -IQSCRHVATKLIQGNEYIFRVSAVNHYGKGEP-VQSEPVKMVDRFGPP----------- 14267
Query: 849 YIRRVGEAVNLVIPFQGKPRPELTWKKD----GAEIDKNQINIRNSETDTIIFIRKAERS 904
G + K ++WK+ G+EI + R E ++ ++R +
Sbjct: 14268 -----GPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERR--EKKSLRWVRAIKTP 14320
Query: 905 HSGKYDLQVKVDKFVETASIDIQIIDR-----------------------PGPPQIVKIE 941
S DL+ KV E ++ + ++ PGPP +
Sbjct: 14321 VS---DLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVT 14377
Query: 942 DVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGN-- 999
D ++ +L W P DG ITGY ++ W I+ T+ IT+ V+ +
Sbjct: 14378 DTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAW---IKDTTGTALRITQFVVPDLQ 14434
Query: 1000 ---EYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNT 1056
+Y FR+ + N G+ E A + D +I + + DF+ L T
Sbjct: 14435 TKEKYNFRISAINDAGVGEPAVIP--------DVEIVEREMAPDFELDAE------LRRT 14480
Query: 1057 YAI-AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGG 1115
+ AG + + ++G P P++TW K+ + + + R + + + L I + + YD G
Sbjct: 14481 LVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKN--RANIENTESFTLLIIPECNRYDTG 14538
Query: 1116 TYCCKAVNDLG 1126
+ N G
Sbjct: 14539 KFVMTIENPAG 14549
Score = 85.1 bits (209), Expect = 3e-16
Identities = 105/480 (21%), Positives = 179/480 (37%), Gaps = 70/480 (14%)
Query: 672 DLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTD 731
D C+E + A E I +N I + KP P+ P + +D VT
Sbjct: 15904 DACREDVGHYVVKLTNSAGEA-IETLNVIVLDKPGPPTGP------------VKMDEVTA 15950
Query: 732 TTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLID 791
++T+ W PP + G + ++ Y++E D W + + +
Sbjct: 15951 DSITLSWGPPKYDGGSSINNYIVE------------------KRDTSTTTWQIVSAT-VA 15991
Query: 792 KTKFTITGLPTDAKIFVRVKAVNAAGAS-----EPKYYSQPILVKEIIEPPKIRIPRH-- 844
+T L T + R+ A N G S EP P V P + +
Sbjct: 15992 RTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDS 16051
Query: 845 LKQTYIRRVGEAVNLVIPF--QGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAE 902
++ + + + + VI + + K R + W K ++K I +T + + E
Sbjct: 16052 MEVQWNEPISDGGSRVIGYHLERKERNSILWVK----LNKTPIPQTKFKTTGLEEGVEYE 16107
Query: 903 RSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAA 962
S + + + V + D PG P+ + + +V L W P DG +
Sbjct: 16108 FRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIIVTR---NSVTLQWKKPTYDGGSK 16164
Query: 963 ITGYTIQKADKKSMEWFTV-IEHYHRTSATITELVIGNEYYFRVFSENMCGL-SEDATMT 1020
ITGY ++K + W + T +T LV + Y FRV + N G+ SE + T
Sbjct: 16165 ITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSEST 16224
Query: 1021 KESAVIARDG----KIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKP 1076
A+ ARD +I +P Y+D AG + ++ + G P P
Sbjct: 16225 --GAITARDEVDPPRISMDPKYKD--------------TIVVHAGESFKVDADIYGKPIP 16268
Query: 1077 KITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
I W+K + + R + S +L ++ D G Y KA N G + ++V
Sbjct: 16269 TIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKV 16328
Score = 85.1 bits (209), Expect = 3e-16
Identities = 100/435 (22%), Positives = 171/435 (39%), Gaps = 65/435 (14%)
Query: 720 PPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPA 779
PP + +D V+ ++T+ W PP++ G + Y++E ST+
Sbjct: 19185 PPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTT---------------- 19228
Query: 780 EDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPP-- 837
W + ++ + +T I L T ++ RV A N G S S ++ + PP
Sbjct: 19229 --WHIVSQ-AVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSE-SSAVVAEYPFSPPGP 19284
Query: 838 --KIRIPRHLKQTYIRR----VGEAVNLVIPF--QGKPRPELTWKKDGAEIDKNQINIRN 889
++ K T + V + + VI + + K R + W K N+I I
Sbjct: 19285 PGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSK------ANKILI-- 19336
Query: 890 SETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQII------DRPGPPQIVKIEDV 943
DT + + + +Y + + + S + + D PG P++ I
Sbjct: 19337 --ADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTNITR- 19393
Query: 944 WGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV-IEHYHRTSATITELVIGNEYY 1002
++V+L W+ P DG A ITGY +++ + W + T +TEL Y
Sbjct: 19394 --KSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFEVTELTEDQRYE 19451
Query: 1003 FRVFSENMC-GLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAG 1061
FRVF+ N +SE + T +I +D + V D F + + AG
Sbjct: 19452 FRVFARNAADSVSEPSEST--GPIIVKDD-VEPPRVMMDVKFRDVIVVK---------AG 19499
Query: 1062 YNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKA 1121
+N + G P P I+W K+ + I + R + S L ++ D G Y
Sbjct: 19500 EVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTL 19559
Query: 1122 VNDLGT--VEIECKL 1134
N GT V + CK+
Sbjct: 19560 KNVAGTRSVAVNCKV 19574
Score = 84.0 bits (206), Expect = 8e-16
Identities = 100/460 (21%), Positives = 169/460 (36%), Gaps = 78/460 (16%)
Query: 697 VNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEY 756
+ + + P P PF + + ++ W P G + + Y++E
Sbjct: 12679 IKVVVMDAPGPPQPPF------------DISDIDADACSLSWHIPLEDGGSNITNYIVEK 12726
Query: 757 CFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAA 816
C D+ DW+ A + KT + L + RV+A N
Sbjct: 12727 C------------------DVSRGDWVTALAS-VTKTSCRVGKLIPGQEYIFRVRAENRF 12767
Query: 817 GASEPKYYSQPILVKEI-----IEPPKIRIPRHLKQ----TYIRRVGEAVNLVIPF--QG 865
G SEP + P +V + EP R+ + K + R + + +I + +
Sbjct: 12768 GISEP--LTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIER 12825
Query: 866 KPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERS------HSGKYDLQVKVDKFV 919
K R L W K N +R++E + E S + K ++V
Sbjct: 12826 KERNSLLWVK------ANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYV 12879
Query: 920 ETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF 979
TA + + D PG P+++ DV V+L W PK DG + I GY ++ +W
Sbjct: 12880 -TARMPV---DPPGKPEVI---DVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWV 12932
Query: 980 ---TVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNP 1036
T + T T L +Y FR + +S + + ++A + P
Sbjct: 12933 RCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENV-----P 12987
Query: 1037 VYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMF 1096
D + + T AG N L+ +V G P P ++W K+ + +M
Sbjct: 12988 PRIDLSVAMKSLLTVK-------AGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMA 13040
Query: 1097 SNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
+ +CTLE+ + D G Y A N G+ KL+V
Sbjct: 13041 MQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKV 13080
Score = 82.8 bits (203), Expect = 2e-15
Identities = 59/194 (30%), Positives = 92/194 (47%), Gaps = 21/194 (10%)
Query: 547 IPISGEPPPKAMWSRGDKAIMEGSGRIRTE-------SYPDSSTLVIDIAERDDSGVYHI 599
+ + EPP + ++E R+ T + PD + V D+ E + + +
Sbjct: 7895 VDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQ-FQV 7953
Query: 600 NLKNEAGEAHASIKVKVVDFPDPPVAPT------VTEVGDDWCIMNWEPPAYDGGSPILG 653
+NEAG H S +++ DP P+ VT+ G + W+PP +GGSPI+G
Sbjct: 7954 RAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIG 8013
Query: 654 YFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVA----YEVRIFAVNAIGISKPSMPS 709
Y +E + +WMR+N K+ F K+ EGV Y +R+ AVNAIG+S+PS S
Sbjct: 8014 YHVEMCPVGTEKWMRVNSRPIKDLKF---KVEEGVVPDKEYVLRVRAVNAIGVSEPSEIS 8070
Query: 710 RPFVPLAVTSPPTL 723
V PT+
Sbjct: 8071 ENVVAKDPDCKPTI 8084
Score = 80.9 bits (198), Expect = 6e-15
Identities = 77/261 (29%), Positives = 107/261 (40%), Gaps = 22/261 (8%)
Query: 464 WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPD--AYNVTLPAKVHVIDP 521
W K+G V+ SDRL + + L + ++ D G Y + + T V VI
Sbjct: 8115 WHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGL 8174
Query: 522 PKIILDGLDADNTVTVIAGNKLRLEIP--ISGEPPPKAMWSRGDKA------IMEGSGRI 573
P D +D T + KL E P G P + R + +M G ++
Sbjct: 8175 PGPCKDIKASDITK---SSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKL 8231
Query: 574 R---TESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTE 630
+ P+ A G +I LKN I PDPPV V
Sbjct: 8232 SWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPV------IAQDPKQPPDPPVDVEVHN 8285
Query: 631 VGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAY 690
+ + W+PP YDGGS I+GY IE+ K RW R N L T+ K + EG Y
Sbjct: 8286 PTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEY 8345
Query: 691 EVRIFAVNAIGISKPSMPSRP 711
+ R+ A NA GIS+PS + P
Sbjct: 8346 QFRVRAENAAGISEPSRATPP 8366
Score = 77.8 bits (190), Expect = 5e-14
Identities = 66/264 (25%), Positives = 116/264 (43%), Gaps = 27/264 (10%)
Query: 263 QVDKGGRVRFVVELADPKLEVKWYKNGQEI----RPSTKYIFEHKGCQRILFINNCQMTD 318
QV + R E+ + ++ WYK+G EI + KY+ E + +FI+ + +D
Sbjct: 3111 QVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERR--IHRMFISETRQSD 3168
Query: 319 DSEYYVTAGDEKCSTELFVREP-PIMVTKQLEDTTAYCGERVELECEVS-EDDANVKWFK 376
EY AG + S L+V P P V ++L+ T G+ +S + W+K
Sbjct: 3169 AGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYK 3228
Query: 377 NGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAA--------EYSVMTTGGQSSAKL-- 426
+ + G K ++ +G+++ L++ A DAA +Y V TT S ++
Sbjct: 3229 EEQLLSTGFKCKF--LHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPE 3286
Query: 427 ------SVDLKPLKILTPLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKV 479
+ + P I+TPL D + G+ +C +S ++ W ++ S ++
Sbjct: 3287 VVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRM 3346
Query: 480 VHKGRIHKLVIANALTEDEGDYVF 503
++L IA A EDEG Y F
Sbjct: 3347 TQFEDTYQLEIAEAYPEDEGTYTF 3370
Score = 77.8 bits (190), Expect = 5e-14
Identities = 104/452 (23%), Positives = 164/452 (36%), Gaps = 62/452 (13%)
Query: 697 VNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEY 756
++ I + KP P P + D V+ V + W PP + G + Y++E
Sbjct: 18092 LSVIVLEKPGPPVGP------------VRFDEVSADFVVISWEPPAYTGGCQISNYIVE- 18138
Query: 757 CFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAA 816
D W + + + +T IT L T + R+ A N
Sbjct: 18139 -----------------KRDTTTTTWHMVSAT-VARTTIKITKLKTGTEYQFRIFAENRY 18180
Query: 817 GASEPKYYSQPILV----KEIIEPPKIRIPRHLKQTYIRRVGEAVN------LVIPFQGK 866
G S P S+ ++V KE P + K + + E VN + + K
Sbjct: 18181 GKSAP-LDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQK 18239
Query: 867 PRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDI 926
+ + W K ++K I +T + + E S + + + V +
Sbjct: 18240 EKNSILWVK----LNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVAR 18295
Query: 927 QIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV-IEHY 985
D PG P+ + I NV L W P DG + ITGY ++K D W +
Sbjct: 18296 DPCDPPGRPEAIVITR---NNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNV 18352
Query: 986 HRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSE 1045
T T++ LV Y FRV + N G + + A+ ARD N +
Sbjct: 18353 LETEFTVSGLVEDQRYEFRVIARNAAGNFSEPS-DSSGAITARDEIDAPNASLD------ 18405
Query: 1046 APMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDD-PRYRMFSNQGVCTL 1104
P + +V AG L +RG P P + W K+ + + R + S TL
Sbjct: 18406 -PKYKDVIV---VHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTL 18461
Query: 1105 EIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
++ DGG Y K N GT I ++V
Sbjct: 18462 VVKDCIRTDGGQYILKLSNVGGTKSIPITVKV 18493
Score = 77.4 bits (189), Expect = 7e-14
Identities = 102/462 (22%), Positives = 169/462 (36%), Gaps = 81/462 (17%)
Query: 696 AVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLE 755
++ + + KP P P + D V+ ++T+ W PP + G + Y+++
Sbjct: 17009 SIEIVTLDKPDPPKGP------------VKFDDVSAESITLSWNPPLYTGGCQITNYIVQ 17056
Query: 756 YCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNA 815
D W V + + +T +T L T + R+ A N
Sbjct: 17057 ------------------KRDTTTTVWDVVSAT-VARTTLKVTKLKTGTEYQFRIFAENR 17097
Query: 816 AGASEPKYYSQPILVKEIIE---PPKIRIPRHL-KQTYIRRVGEAVN------LVIPFQG 865
G S S PI+ + + PP + K + + + E VN + +
Sbjct: 17098 YGQSFA-LESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLER 17156
Query: 866 KPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSG-KYDLQVKVDKFVETAS- 923
K R + W K ++K I+ DT KA+ G +Y+ +V + V
Sbjct: 17157 KERNSILWTK----VNKTIIH------DTQF---KAQNLEEGIEYEFRVYAENIVGVGKA 17203
Query: 924 -------IDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSM 976
+ D PG P+ + ++ + L WT P DG + ITGY ++K D
Sbjct: 17204 SKNSECYVARDPCDPPGTPEPIMVKR---NEITLQWTKPVYDGGSMITGYIVEKRDLPDG 17260
Query: 977 EWFTV-IEHYHRTSATITELVIGNEYYFRVFSENMCG-LSEDATMTKESAVIARDGKIYK 1034
W + T T++ L Y FRV ++N G +S+ + T G I
Sbjct: 17261 RWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDST---------GPITA 17311
Query: 1035 NPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYR 1094
E S P F +V AG L V G P P I W++ I + R
Sbjct: 17312 KDEVELPRISMDPKFRDTIVVN---AGETFRLEADVHGKPLPTIEWLRGDKEIEESARCE 17368
Query: 1095 MFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
+ + L ++ DGG Y +A N G+ ++V
Sbjct: 17369 IKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKV 17410
Score = 77.0 bits (188), Expect = 9e-14
Identities = 106/469 (22%), Positives = 169/469 (36%), Gaps = 97/469 (20%)
Query: 697 VNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEY 756
+ I + KP P+ P + +D + T++T+ W PP+ G A L GYV+E
Sbjct: 23519 IKVIILDKPGPPTGP------------IKIDEIDATSITISWEPPELDGGAPLSGYVVEQ 23566
Query: 757 CFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAA 816
D W+ ++ + ++ F T L + RV A N
Sbjct: 23567 ------------------RDAHRPGWLPVSES-VTRSTFKFTRLTEGNEYVFRVAATNRF 23607
Query: 817 GASEPKYYSQPILVKEIIE-PPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTW-- 873
G L E+IE IRIP G L I + LTW
Sbjct: 23608 GIGS-------YLQSEVIECRSSIRIP-----------GPPETLQIFDVSRDGMTLTWYP 23649
Query: 874 -KKDGAE------IDKNQINIR-----NSETDTIIFIRKAERSHSGKYDLQVKVDKFVET 921
+ DG +++ ++ N T+ R + +Y+ +V +
Sbjct: 23650 PEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGS 23709
Query: 922 AS--------IDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADK 973
+ + I PG PQ ++ D +V+L W+ P+D+G + +TGY I+
Sbjct: 23710 GKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKV 23769
Query: 974 KSMEWF------TVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIA 1027
EW T I Y T+T L G EY FRV + N G E A +
Sbjct: 23770 DQHEWTKCNTTPTKIREY-----TLTHLPQGAEYRFRVLACNAGGPGEPAE-------VP 23817
Query: 1028 RDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAI 1087
K+ + Y D++ E + + G L ++G P P W K I
Sbjct: 23818 GTVKVTEMLEYPDYELDE-----RYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDI 23872
Query: 1088 VDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
R + +++ L I++ D GTY N G + K+ V
Sbjct: 23873 --SKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRV 23919
Score = 73.9 bits (180), Expect = 8e-13
Identities = 64/235 (27%), Positives = 91/235 (38%), Gaps = 46/235 (19%)
Query: 932 PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRT-SA 990
P PP V++ + E + +TW PP DG + I GY I+K K W EH +
Sbjct: 8275 PDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTY 8334
Query: 991 TITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFT 1050
T L G EY FRV +EN G+SE + T + + + D + + T
Sbjct: 8335 TAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAV------------DPIDAPKVILRT 8382
Query: 1051 QPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDD-------PRYRM-------- 1095
V G L+ S+ G+P P ITW+K++ IV + P R
Sbjct: 8383 SLEVKR----GDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEE 8438
Query: 1096 --------------FSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
S +G L +R D G Y K ND G + C + V
Sbjct: 8439 EPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSV 8493
Score = 73.9 bits (180), Expect = 8e-13
Identities = 59/203 (29%), Positives = 83/203 (40%), Gaps = 14/203 (6%)
Query: 926 IQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHY 985
++ + P PP + I D+ V+L W PK DG + ITGY I+ K S +W T I
Sbjct: 14654 VKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQW-THITTV 14712
Query: 986 HRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSE 1045
+ L G EY F+V + N G S +ES + + + + + D
Sbjct: 14713 KGLECVVRNLTEGEEYTFQVMAVNSAGRSAP----RESRPVI----VKEQTMLPELDLRG 14764
Query: 1046 APMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLE 1105
Q LV A AG N + V G PKP +TW K + R + L
Sbjct: 14765 ---IYQKLV--IAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILN 14819
Query: 1106 IRKPSPYDGGTYCCKAVNDLGTV 1128
I + D G Y A N +G V
Sbjct: 14820 INECVRSDSGPYPLTARNIVGEV 14842
Score = 73.2 bits (178), Expect = 1e-12
Identities = 52/197 (26%), Positives = 86/197 (43%), Gaps = 13/197 (6%)
Query: 930 DRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTS 989
++P PP+ + + D + L W P DG + ITGY ++ K S W H + +
Sbjct: 22239 EQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEA-GHTKQLT 22297
Query: 990 ATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMF 1049
T+ LV EY FRV ++N G SE S+VI ++ +I ++
Sbjct: 22298 FTVERLVEKTEYEFRVKAKNDAGYSEPREAF--SSVIIKEPQIEPT--------ADLTGI 22347
Query: 1050 TQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKP 1109
T L+ A G T++ + G P PK+TW ++ + + R + + + TL ++
Sbjct: 22348 TNQLITCKA--GSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDS 22405
Query: 1110 SPYDGGTYCCKAVNDLG 1126
D G Y N G
Sbjct: 22406 MRGDSGRYFLTLENTAG 22422
Score = 72.4 bits (176), Expect = 2e-12
Identities = 56/222 (25%), Positives = 101/222 (45%), Gaps = 17/222 (7%)
Query: 918 FVETASIDI--QIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKS 975
FVET+ + + I P P+ +++++V V LTW PPK DG + I Y ++ +
Sbjct: 10396 FVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGT 10455
Query: 976 MEWFTVI-EHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYK 1034
++ V ++ T+ L G+ Y +RV + N+ G + + TK I ++
Sbjct: 10456 EKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKP---ITCKDELAP 10512
Query: 1035 NPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYR 1094
++ DF T + +A+ G + G PKPK++W K++ +++D R
Sbjct: 10513 PTLHLDF----RDKLTIRVGEAFALTGRYS-------GKPKPKVSWFKDEADVLEDDRTH 10561
Query: 1095 MFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
+ + LE K D G YC N G+ + C++ V
Sbjct: 10562 IKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNV 10603
Score = 71.6 bits (174), Expect = 4e-12
Identities = 134/663 (20%), Positives = 230/663 (34%), Gaps = 120/663 (18%)
Query: 2 PEPTKKEENEVPAP----APPPEEPSKEKEAGTTPAKDWTLVETPPGEEQAKQNANSQLS 57
PEP K V +P +P P P T P TP + Q +
Sbjct: 26364 PEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKP--------TPTEKVQHLPVSAPPKI 26415
Query: 58 ILFIEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAGKHLQLKETFE 117
F++ + ++I + V +LR + W+K GK L+ F+
Sbjct: 26416 TQFLK------AEASKEIAKLTCVVESSVLRAKEVTWYKD---------GKKLKENGHFQ 26460
Query: 118 RH-SRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFK 176
H S T+E++I ++ G Y CE+
Sbjct: 26461 FHYSADGTYELKINNLTESDQGEYVCEI-------------------------------- 26488
Query: 177 RSGEGQEDAGELDFSG---------LLKRREVKQQEEEPQVDVWELLKNAKPSEYEKIAF 227
SGEG L F G + K E K+ +++ + + +P E I+
Sbjct: 26489 -SGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTEST--VTRKTEPKAPEPIS- 26544
Query: 228 QYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYK 287
K + D D + V +P+ W K
Sbjct: 26545 ---------------------SKPVIVTGLQDTTVSSDSVAKFA-VKATGEPRPTAIWTK 26582
Query: 288 NGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVT----AGDEKCSTELFVREPPIM 343
+G+ I KY L I+ +D Y T AG S +L ++ I
Sbjct: 26583 DGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKA--IK 26640
Query: 344 VTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIE 403
T+ + +T E + V +++ + K ++ E + KS+ ++ ++ + ++I
Sbjct: 26641 DTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLALKEEASKVLIS 26700
Query: 404 GATKADAA---EYSVMTTGGQSSAKLSVDLKP-LKILTPLTDQTVNLGKEICLKCEISEN 459
K AA E S++ +++ S +++ +I T ++N G+ + LK I+
Sbjct: 26701 EEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGA 26760
Query: 460 IPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV--------FAPDAYNVT 511
KW NG+ + S+ + G L I A DEG Y++T
Sbjct: 26761 TDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLT 26820
Query: 512 LPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSG 571
L ++ D P I + + G + ISGEP P+ W + + I S
Sbjct: 26821 LSKELS--DAPAFI----SQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPI-SISS 26873
Query: 572 RIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEV 631
+ + +L I A DSG Y I KN G+ A+ + V+ + P V
Sbjct: 26874 NVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRT 26933
Query: 632 GDD 634
D
Sbjct: 26934 SGD 26936
Score = 68.9 bits (167), Expect = 3e-11
Identities = 107/465 (23%), Positives = 175/465 (37%), Gaps = 76/465 (16%)
Query: 696 AVNAIGISKPSMPSR-PFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVL 754
A NA G +K + + P V P + ++T +T+ W P + G A + Y++
Sbjct: 21728 AKNASGSAKAEIKVKVQDTPGKVVGP---IRFTNITGEKMTLWWDAPLNDGCAPITHYII 21784
Query: 755 EYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVN 814
E E A+ L +D + +T L + RV AVN
Sbjct: 21785 E-----------KRETSRLAWALI--------EDKCEAQSYTAIKLINGNEYQFRVSAVN 21825
Query: 815 AAGASEPKYYSQPILVK---EIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPEL 871
G P S P++ + + + P I P ++ G ++ L RPE
Sbjct: 21826 KFGVGRP-LDSDPVVAQIQYTVPDAPGIPEPSNI-------TGNSITLTWA-----RPE- 21871
Query: 872 TWKKDGAEIDKNQINIRNSE-TDTIIFIRKAERSHS----------GKYDLQVKVDKF-- 918
G+EI + + R + T + I K S + +Y+ V +
Sbjct: 21872 --SDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAG 21929
Query: 919 VETASIDIQII------DRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKAD 972
V AS ++I + PGPP +VK+ D V+L W+ P DG I GY I+
Sbjct: 21930 VGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCK 21989
Query: 973 KKSMEWFTV-IEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGK 1031
+W V E +T T+T+L G EY FRV + N G + +T I +
Sbjct: 21990 ADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVT---GTIKAVDR 22046
Query: 1032 IYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDP 1091
+ + D +F + + AG + L + +G P P W K +
Sbjct: 22047 LTAPELDIDANFKQTHVVR---------AGASIRLFIAYQGRPTPTAVWSKPDSNL--SL 22095
Query: 1092 RYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
R + + TL + + D G Y N+ G+ I ++V
Sbjct: 22096 RADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKV 22140
Score = 64.7 bits (156), Expect = 5e-10
Identities = 75/303 (24%), Positives = 129/303 (42%), Gaps = 19/303 (6%)
Query: 341 PIMVTKQLEDT----TAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGK 396
P+ K+++D + + G EC VS A W K+G I PK +R +GK
Sbjct: 4809 PLKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPK--HRFIADGK 4866
Query: 397 KHILIIEGATKADAAEYSVMTTGGQ----SSAKLSVDLKPLKILTPLTDQ-TVNLGKEIC 451
L I +DA EY+ + G S+AKL V+ P++ + L ++ TV G+ +
Sbjct: 4867 DRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLY 4926
Query: 452 LKCEISENIPGKWTKNG-LPVQESDRLKVVHKGRIHKLVIANALTEDEGDY-VFAPDAYN 509
L CE+++ W K+G + V++ R+ G + L I +A D G Y V +A N
Sbjct: 4927 LSCELNKERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVENANN 4986
Query: 510 VTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEG 569
+ + V V++ +I D L + + + P W +G I
Sbjct: 4987 LECSSCVKVVE---VIRDWLVKPIRDQHVKPKGTAIFACDIAKDTPNIKWFKGYDEI-PA 5042
Query: 570 SGRIRTESYPDSSTLVIDI--AERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT 627
+TE D + L + I A +D Y + ++ + A ++ + V+ P T
Sbjct: 5043 EPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGKRYPAKLTLGEREVELLKPIEDVT 5102
Query: 628 VTE 630
+ E
Sbjct: 5103 IYE 5105
Score = 63.5 bits (153), Expect = 1e-09
Identities = 31/92 (33%), Positives = 43/92 (46%)
Query: 1047 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEI 1106
P L N I G + TL C + G P P +TW + I +++ G+ L I
Sbjct: 897 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMI 956
Query: 1107 RKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1138
R+ D G + C AVN+ GTV C L V+V
Sbjct: 957 REAFAEDSGRFTCSAVNEAGTVSTSCYLAVQV 988
Score = 61.2 bits (147), Expect = 5e-09
Identities = 33/100 (33%), Positives = 54/100 (54%), Gaps = 6/100 (6%)
Query: 931 RPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEH-YHRTS 989
RP PP++ K+ E + + W PP+ DG +ITGY ++K +K S W V +
Sbjct: 12093 RPDPPEVTKVSK---EEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERR 12149
Query: 990 ATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARD 1029
+ L+ +EY FRV +EN G+ E + ++ V+A+D
Sbjct: 12150 MKVQNLLPDHEYQFRVKAENEIGIGEPSLPSR--PVVAKD 12187
Score = 59.7 bits (143), Expect = 2e-08
Identities = 74/324 (22%), Positives = 129/324 (39%), Gaps = 19/324 (5%)
Query: 829 LVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQ--GKPRPELTWKKDGAEID----- 881
L +E P + P + + ++++ E ++V Q G P+P + WKK G +
Sbjct: 1023 LTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRY 1082
Query: 882 KNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIE 941
K N + E +I + A+ +G+Y + V+ +K ET S +++ ++K +
Sbjct: 1083 KVSYNKQTGECKLVISMTFAD--DAGEYTIVVR-NKHGET-SASASLLEEADYELLMKSQ 1138
Query: 942 DVWGENVALTWTPPKDDGNAAITGYTIQKADKK-SMEWFTVIEHYHRTSATITELVIGNE 1000
+T + G+ + +K+ E + + + + + V E
Sbjct: 1139 QEMLYQTQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDTVVVRTYVEDQE 1198
Query: 1001 YYFRVFSENMCGLSEDATM-TKESAVIARDGKIYKNPVYEDFDFSEAPM--FTQPLVNTY 1057
++ F E + E + T ++ DG+ + D SEA F + N
Sbjct: 1199 FHISSFEERLIKEIEYRIIKTTLEELLEEDGE---EKMAVDISESEAVESGFDSRIKNYR 1255
Query: 1058 AIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRM-FSNQGVCTLEIRKPSPYDGGT 1116
+ G T +C + G P PKI W K+ I RY+M F G +L I P D G
Sbjct: 1256 ILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGI 1315
Query: 1117 YCCKAVNDLGTVEIECKLEVKVIA 1140
Y A N G KL V+ A
Sbjct: 1316 YTAFASNIKGNAICSGKLYVEPAA 1339
Score = 59.3 bits (142), Expect = 2e-08
Identities = 96/426 (22%), Positives = 148/426 (34%), Gaps = 58/426 (13%)
Query: 717 VTSPPT-LLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAY 775
+ PPT + D V+ VT W PP++ G + YV+E ST+
Sbjct: 14853 IPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTT------------ 14900
Query: 776 DLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIE 835
W+ +I +T + T L T + RVKA N G P S I+
Sbjct: 14901 ------WVELATTVI-RTTYKATRLTTGLEYQFRVKAQNRYGVG-PGITSACIVANY--- 14949
Query: 836 PPKIRIPRHLKQ-TYIRRVGEAVNLVIPF------------QGKPRPELTWKKDGAEIDK 882
P K+ P Q T + + ++ P + K R + W+ +
Sbjct: 14950 PFKVPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVP 15009
Query: 883 NQINIRNSETDTIIF-IRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIE 941
I + TD I + R + +GK K K E + + ID PG P + I
Sbjct: 15010 GNIFKSSGLTDGIAYEFRVIAENMAGKS----KPSKPSEPM-LALDPIDPPGKPVPLNIT 15064
Query: 942 DVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV-IEHYHRTSATITELVIGNE 1000
V L W P+ G IT Y ++K D + W + T++ L
Sbjct: 15065 R---HTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAA 15121
Query: 1001 YYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIA 1060
Y FRV ++N G + ++ D + K V D F + + A
Sbjct: 15122 YEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKV--DVKFKDTVILK---------A 15170
Query: 1061 GYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCK 1120
G L V G P P + W K+ + + + L + + D G Y
Sbjct: 15171 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLT 15230
Query: 1121 AVNDLG 1126
A N G
Sbjct: 15231 ATNPGG 15236
Score = 57.4 bits (137), Expect = 8e-08
Identities = 95/406 (23%), Positives = 148/406 (36%), Gaps = 54/406 (13%)
Query: 694 IFAVNAIGISKPSMPSRPFVPLAVTSPPT-LLTVDSVTDTTVTMRWRPPDHIGAAGLDGY 752
I AVN +G + M L PP + +SV+ +T+ W PP G + + Y
Sbjct: 9891 ITAVNNLGTASKEMRLNV---LGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNY 9947
Query: 753 VLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKA 812
V+E + + W+ + + + T +TI L + R+ A
Sbjct: 9948 VIE------------------KREANRKTWVHVSSEPKECT-YTIPKLLEGHEYVFRIMA 9988
Query: 813 VNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIP-FQGKPRPEL 871
N G EP S+P + + P P + + R VN P + G
Sbjct: 9989 QNKYGIGEP-LDSEPETARNLFSVPGA--PDKPTVSSVTRNSMTVNWEEPEYDGGSPVTG 10045
Query: 872 TW--KKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKF----VETASID 925
W KD ++N + T+ K G D Q +V V AS+
Sbjct: 10046 YWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEGS-DYQFRVYAINAAGVGPASLP 10104
Query: 926 IQI------IDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF 979
I PGPP K+ D + L W+PP DG + +TGY ++ ++ EW
Sbjct: 10105 SDPATARDPIAPPGPP-FPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWE 10163
Query: 980 TVIEHYHR-TSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVY 1038
+ R T +T L G Y FRV + N+ G+ E +T VI ++ +
Sbjct: 10164 KGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTD---VIEMKDRLVSPDLQ 10220
Query: 1039 EDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNK 1084
D + AG + V G P P +TW N+
Sbjct: 10221 LDASVRD---------RIVVHAGGVIRIIAYVSGKPPPTVTWNMNE 10257
Score = 57.0 bits (136), Expect = 1e-07
Identities = 43/167 (25%), Positives = 72/167 (43%), Gaps = 11/167 (6%)
Query: 345 TKQLEDTTAYCGERVELECEVSEDDA-NVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIE 403
T+ L+ G E +S V WF++G+ I +I + L I
Sbjct: 9 TQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIP 68
Query: 404 GATKADAAEYSVMTTGGQSSAKLSVDL------KPLKILTPLTDQTVNLGKEICLKCEIS 457
TKA++ YS+ T G A + +L P + L TV G ++ L+ ++
Sbjct: 69 AVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVT 128
Query: 458 ENIPG---KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 501
IP K+ ++G +Q S ++ +G ++ L+IA A ED G Y
Sbjct: 129 -GIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTY 174
Score = 56.6 bits (135), Expect = 1e-07
Identities = 39/140 (27%), Positives = 56/140 (40%), Gaps = 9/140 (6%)
Query: 1003 FRVFSENMCGLSEDATM---TKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI 1059
F+ E + +SE T ES V + P+ S P+ L +T
Sbjct: 26506 FKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPI------SSKPVIVTGLQDTTVS 26559
Query: 1060 AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCC 1119
+ A G P+P W K+ AI +Y++ ++G LEI K D G Y C
Sbjct: 26560 SDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTC 26619
Query: 1120 KAVNDLGTVEIECKLEVKVI 1139
N G+V CKL +K I
Sbjct: 26620 TVKNSAGSVSSSCKLTIKAI 26639
Score = 56.6 bits (135), Expect = 1e-07
Identities = 74/348 (21%), Positives = 121/348 (34%), Gaps = 77/348 (22%)
Query: 865 GKPRPELTWKKDGAEIDKN-QINIRNSETDTIIFIRKAERSHSGKYD------------- 910
G+PRP W KDG I + + + + + I K + S SG Y
Sbjct: 26572 GEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSS 26631
Query: 911 --LQVKVDKFVETASIDIQIIDRPGPPQIVKIED------VWGENVALTWTPP------K 956
L +K K E + Q P + +++ + E + ++ K
Sbjct: 26632 CKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLALK 26691
Query: 957 DDGNAAITGYTIQKADKKSMEWFTVIEHYHRTS-------------ATITELVIGNEYYF 1003
++ + + ++K+ S+E V E +TS A T++ I NE
Sbjct: 26692 EEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSI-NEGQR 26750
Query: 1004 RVFSENMCGLSE-----------------------DATMT------KESAVIARDGKIYK 1034
V N+ G ++ D T+T ++ ++ K +
Sbjct: 26751 LVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKE 26810
Query: 1035 NPVYEDFDF------SEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIV 1088
V +D S+AP F + G N C + G P P+I W KN + I
Sbjct: 26811 GIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPIS 26870
Query: 1089 DDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
+ ++ V +LEIR S D G Y KA N G L V
Sbjct: 26871 ISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 26918
Score = 54.7 bits (130), Expect = 5e-07
Identities = 52/221 (23%), Positives = 77/221 (34%), Gaps = 45/221 (20%)
Query: 920 ETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF 979
+TA D++++ RP P E W DG + YT +
Sbjct: 1426 QTARFDLKVVGRPMP------ETFWFH-----------DGQQIVNDYTHK---------- 1458
Query: 980 TVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYE 1039
VI+ S I + + V ++N G S + + AV
Sbjct: 1459 VVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAV-------------- 1504
Query: 1040 DFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDD--PRYRMFS 1097
+ PMF + L N G + GNP P I W+KN IV P+ R+
Sbjct: 1505 --EHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEG 1562
Query: 1098 NQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1138
+G L+I D Y A+N G CK+ V+V
Sbjct: 1563 TKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEV 1603
Score = 51.2 bits (121), Expect = 5e-06
Identities = 56/305 (18%), Positives = 122/305 (40%), Gaps = 22/305 (7%)
Query: 842 PRHLKQTYIRRVGEAVNLVIPFQ--GKPRPELTWKKDGAEID-KNQINIRNSETDTIIFI 898
P + Q + + E N++ + G+P PE+ W K+ I + ++I S + I
Sbjct: 26829 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEI 26888
Query: 899 RKAERSHSGKYDLQVKVDKFVETASIDIQIIDR-PGPPQIVKIEDVWGENVALTWTPPKD 957
R A S SGKY ++ K + +A+ + ++ P + V + ++ +++
Sbjct: 26889 RNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFSSQSV 26948
Query: 958 DGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDA 1017
+A+ + S T ++ ++ +++ + E + + S + G+S
Sbjct: 26949 QMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSM---QESFVEMSSSSFMGISNMT 27005
Query: 1018 TMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI-AGYNATLNCSVRGNPKP 1076
+ ++ + + G P + L + +I G T+ C+ G P P
Sbjct: 27006 QLESSTSKMLKAG------------IRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTP 27053
Query: 1077 KITWM--KNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKL 1134
++TW K+ + R+ + + + TL I DGG Y N+ G+ +
Sbjct: 27054 EVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNI 27113
Query: 1135 EVKVI 1139
++ I
Sbjct: 27114 HIRSI 27118
Score = 49.7 bits (117), Expect = 2e-05
Identities = 111/565 (19%), Positives = 201/565 (35%), Gaps = 77/565 (13%)
Query: 110 LQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNI 169
L++ E + YTF + + N EV D+ S +V ES +
Sbjct: 3355 LEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEVQALDRQSSGK---DVRESAKSQAVA 3411
Query: 170 DIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLKNAKPSEYEKIAFQY 229
D + S Q++ F G EV+ E Q + A + ++
Sbjct: 3412 DSSFTKEESKISQKEIKS--FQGSSYEYEVQVFESVSQSSI----HTAASVQDTQLCHTA 3465
Query: 230 GITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPK-LEVKWYKN 288
++ + + K +E A + V G +F+ L D ++V W
Sbjct: 3466 SLSQIAESTELSKECAKESTGEAPKIFLHLQDVTVKCGDTAQFLCVLKDDSFIDVTWTHE 3525
Query: 289 GQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY----YVTAGDEKCSTELFVREPPIMV 344
G +I S + G + L I N Q+ D Y + G+ S L V P +
Sbjct: 3526 GAKIEESERLKQSQNGNIQFLTICNVQLVDQGLYSCIVHNDCGERTTSAVLSVEGAPESI 3585
Query: 345 TKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEG 404
ER+E E E+ + + + EE + + + ++ +L
Sbjct: 3586 LH----------ERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLS-KINETLELL---- 3630
Query: 405 ATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPG-- 462
+E V T S + + + + +++ +++G L + IP
Sbjct: 3631 ------SESPVYPTKFDSEKEGTGPI----FIKEVSNADISMGDVATLSVTVI-GIPKPK 3679
Query: 463 -KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV-FAPDAYNVTLPAKVHVID 520
+W NG+ + S K V G H L+I EDEG+Y A + Y T+ + I+
Sbjct: 3680 IQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKIN 3739
Query: 521 PPKIILDGLDADNTVTVIAGNKLRL-------------------------EIPISGEPPP 555
+G T + +A + +L E + GEP P
Sbjct: 3740 SKG---EGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAP 3796
Query: 556 KAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVK 615
W + +K + + S T +++ +R+DSG+Y +N GE+ + ++
Sbjct: 3797 TVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELL 3856
Query: 616 VV----DFPDPPV-APTVTEVGDDW 635
V+ D D P A + E +D+
Sbjct: 3857 VLLEDTDMTDTPCKAKSTPEAPEDF 3881
Score = 48.9 bits (115), Expect = 3e-05
Identities = 59/283 (20%), Positives = 97/283 (34%), Gaps = 70/283 (24%)
Query: 854 GEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQV 913
GE+V L G P P +TW ++ +I+
Sbjct: 911 GESVTLECHISGYPSPTVTWYREDYQIE-------------------------------- 938
Query: 914 KVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADK 973
+SID QI + G +++ E ++ T + + G + + Y +
Sbjct: 939 --------SSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ--- 987
Query: 974 KSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIY 1033
V E + + + +TE E + F E+ + D ++T+E A Y
Sbjct: 988 -------VSEEFEKETTAVTEKFTTEE---KRFVESRDVVMTDTSLTEEQAGPGEPAAPY 1037
Query: 1034 KNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRY 1093
T+P+V + G + C V GNPKP + W K+ V + RY
Sbjct: 1038 --------------FITKPVVQKL-VEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRY 1082
Query: 1094 RMFSNQ--GVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKL 1134
++ N+ G C L I D G Y N G L
Sbjct: 1083 KVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125
Score = 48.9 bits (115), Expect = 3e-05
Identities = 86/372 (23%), Positives = 145/372 (38%), Gaps = 68/372 (18%)
Query: 784 VANKDLIDKTKFTITGLPTDAKIFVRV---KAVNAAGASE-PKYYSQPILVKEIIEPPKI 839
V +DL+ K ++G+P + ++ +++ +A+ AA ASE P +S+ + E +E +
Sbjct: 4201 VQGRDLLSKESL-LSGIPEEQRLNLKIQICRALQAAVASEQPGLFSEWLRNIEKVEVEAV 4259
Query: 840 RI---PRHLKQTYI----RRVGEAVNLVIPFQGKPRPELTWKKDGA--EIDKNQINIRNS 890
I PRH+ Y+ + V E V ++I L + A I +I+I +
Sbjct: 4260 NITQEPRHIMCMYLVTSAKSVTEEVTIIIEDVDPQMANLKMELRDALCAIIYEEIDILTA 4319
Query: 891 ETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVA- 949
E I K LQ ++D F + ++ ++ E+V NV
Sbjct: 4320 EGPRI--------QQGAKTSLQEEMDSFSGSQKVEPITEPEVESKYLISTEEVSYFNVQS 4371
Query: 950 ----LTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRV 1005
L TP +A+ +D+K E E +S+
Sbjct: 4372 RVKYLDATPVTKGVASAVV------SDEKQDESLKPSEEKEESSSE-------------- 4411
Query: 1006 FSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNAT 1065
G E AT+ + A +G + K + PM PLV+T + G
Sbjct: 4412 -----SGTEEVATVKIQEA----EGGLIKE---------DGPMIHTPLVDTVSEEGDIVH 4453
Query: 1066 LNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDG-GTYCCKAVND 1124
L S+ N K ++ W + D +++ +Q TL I K + D G Y C+A+ND
Sbjct: 4454 LTTSIT-NAK-EVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALND 4511
Query: 1125 LGTVEIECKLEV 1136
G KL V
Sbjct: 4512 SGKTATSAKLTV 4523
Score = 48.1 bits (113), Expect = 5e-05
Identities = 51/213 (23%), Positives = 86/213 (40%), Gaps = 21/213 (9%)
Query: 932 PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSAT 991
P P+ + + + L W P+ +G + I GY I+K ++ V + T++
Sbjct: 8990 PTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSF 9049
Query: 992 ITELVIGNEYY-FRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFT 1050
+ E + ++ Y FRV + N G SE + V+ +D ++ +
Sbjct: 9050 LVENLDEHQMYEFRVKAVNEIGESEPSLPLN---VVIQDDEVPPT----------IKLRL 9096
Query: 1051 QPLVNTYAI-AGYNATLNCSVRGNPKPKITWMKNKVAI------VDDPRYRMFSNQGVCT 1103
+T + AG + V G P PKI W KN+ I + + + ++
Sbjct: 9097 SVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTE 9156
Query: 1104 LEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
L I K D GTY A N LG+V +EV
Sbjct: 9157 LSIPKAVREDKGTYTVTASNRLGSVFRNVHVEV 9189
Score = 47.8 bits (112), Expect = 6e-05
Identities = 61/279 (21%), Positives = 101/279 (36%), Gaps = 22/279 (7%)
Query: 266 KGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVT 325
+G RF ++ L+V WY ++I+PS + L I D+ Y
Sbjct: 3312 EGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFV 3371
Query: 326 A----GDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEI 381
A G + L + + +D + + +++++ + + +EI
Sbjct: 3372 ASNAVGQVSSTANLSLEVQALDRQSSGKDVRESAKSQAVADSSFTKEESKI----SQKEI 3427
Query: 382 IPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDL----------K 431
S Y V+ + + T A + + T S S +L +
Sbjct: 3428 KSFQGSSYEYEVQVFESVSQSSIHTAASVQDTQLCHTASLSQIAESTELSKECAKESTGE 3487
Query: 432 PLKILTPLTDQTVNLGKEICLKCEISEN--IPGKWTKNGLPVQESDRLKVVHKGRIHKLV 489
KI L D TV G C + ++ I WT G ++ES+RLK G I L
Sbjct: 3488 APKIFLHLQDVTVKCGDTAQFLCVLKDDSFIDVTWTHEGAKIEESERLKQSQNGNIQFLT 3547
Query: 490 IANALTEDEGDY--VFAPDAYNVTLPAKVHVIDPPKIIL 526
I N D+G Y + D T A + V P+ IL
Sbjct: 3548 ICNVQLVDQGLYSCIVHNDCGERTTSAVLSVEGAPESIL 3586
Score = 47.4 bits (111), Expect = 8e-05
Identities = 28/96 (29%), Positives = 44/96 (45%), Gaps = 2/96 (2%)
Query: 1044 SEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDD--PRYRMFSNQGV 1101
++AP FTQPL + + G AT + G P P+++W ++ I P ++ + G
Sbjct: 3 TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGR 62
Query: 1102 CTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1137
L I + + G Y KA N G +L VK
Sbjct: 63 AKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98
Score = 46.6 bits (109), Expect = 1e-04
Identities = 36/105 (34%), Positives = 48/105 (45%), Gaps = 4/105 (3%)
Query: 512 LPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSG 571
+PA V + P ++ GL VTVI G + LE ISG P P W R D I E S
Sbjct: 886 VPAPVEIPVTPPTLVSGL---KNVTVIEGESVTLECHISGYPSPTVTWYREDYQI-ESSI 941
Query: 572 RIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKV 616
+ + L+I A +DSG + + NEAG S + V
Sbjct: 942 DFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 986
Score = 46.6 bits (109), Expect = 1e-04
Identities = 29/93 (31%), Positives = 42/93 (45%), Gaps = 3/93 (3%)
Query: 1047 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIV---DDPRYRMFSNQGVCT 1103
P FT PL N A G N ++ +P+P +TW K+ I +D +Y S++G+
Sbjct: 25385 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQ 25444
Query: 1104 LEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
L I + D Y A N G + KL V
Sbjct: 25445 LTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25477
Score = 46.2 bits (108), Expect = 2e-04
Identities = 34/107 (31%), Positives = 47/107 (43%), Gaps = 4/107 (3%)
Query: 1034 KNPVYEDFDFSE----APMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVD 1089
++PVY SE P+F + + N G ATL+ +V G PKPKI W N V +
Sbjct: 3632 ESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTP 3691
Query: 1090 DPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
Y+ + +L I D G Y C A ND G L++
Sbjct: 3692 SADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKI 3738
Score = 46.2 bits (108), Expect = 2e-04
Identities = 25/93 (26%), Positives = 42/93 (45%)
Query: 1046 APMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLE 1105
AP+ + + G+ A C ++ P + W K I + + + S++ + +LE
Sbjct: 4528 APVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLE 4587
Query: 1106 IRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1138
I + D G Y CKA N+ G+V L V V
Sbjct: 4588 ILRTQVVDCGEYTCKASNEYGSVSCTATLTVTV 4620
Score = 45.8 bits (107), Expect = 2e-04
Identities = 30/96 (31%), Positives = 39/96 (40%), Gaps = 3/96 (3%)
Query: 1047 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSN-QGVCTLE 1105
P F + L G A +V G P P +TW K + Y + N G T
Sbjct: 3767 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3826
Query: 1106 IRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVIAQ 1141
+ P D G Y CKA N LG E C E+ V+ +
Sbjct: 3827 VNDPQREDSGLYICKAENMLG--ESTCAAELLVLLE 3860
Score = 45.8 bits (107), Expect = 2e-04
Identities = 29/100 (29%), Positives = 49/100 (49%), Gaps = 5/100 (5%)
Query: 932 PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEH--YHRTS 989
P P + +V ++ +TW P D G IT Y ++K + S W V + + T
Sbjct: 10707 PDAPDQPIVTEVTKDSALVTWNKPHDGGKP-ITNYILEKRETMSKRWARVTKDPIHPYTK 10765
Query: 990 ATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARD 1029
+ +L+ G +Y FRV +EN G+ + + +K V A+D
Sbjct: 10766 FRVPDLLEGCQYEFRVSAENEIGIGDPSPPSK--PVFAKD 10803
Score = 44.7 bits (104), Expect = 5e-04
Identities = 62/284 (21%), Positives = 105/284 (36%), Gaps = 51/284 (17%)
Query: 869 PELT--WKKDGAEID-KNQINIRNSETDTIIFIRKAERSHSGKYDL----QVKVDK-FVE 920
P++T W KD E+ ++I I+ + + I S +GKY + V K FVE
Sbjct: 3038 PDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVE 3097
Query: 921 TASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNA------AITGYTIQKADKK 974
+ I+ I + +++ + + + + +DD +A + +Q+ K
Sbjct: 3098 GRDVRIRSIKK-------EVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHK- 3149
Query: 975 SMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYK 1034
+ V HR + T EY F V N ++ +Y
Sbjct: 3150 ----YVVERRIHRMFISETRQSDAGEYTF-VAGRNRSSVT-----------------LYV 3187
Query: 1035 NPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYR 1094
N E P Q L +G A + G P+PKI+W K + + + +
Sbjct: 3188 NA-------PEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCK 3240
Query: 1095 MFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1138
+ TL + + P D Y C+A ND G L V+V
Sbjct: 3241 FLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEV 3284
Score = 44.3 bits (103), Expect = 7e-04
Identities = 29/98 (29%), Positives = 51/98 (52%), Gaps = 1/98 (1%)
Query: 534 TVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDD 593
++TV G+++RL++ ++G P P + R D A ++ S + D +L+I A +D
Sbjct: 112 SMTVRQGSQVRLQVRVTGIPTPVVKFYR-DGAEIQSSLDFQISQEGDLYSLLIAEAYPED 170
Query: 594 SGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEV 631
SG Y +N N G A ++ ++ V + P T T V
Sbjct: 171 SGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIV 208
Score = 44.3 bits (103), Expect = 7e-04
Identities = 64/320 (20%), Positives = 110/320 (34%), Gaps = 40/320 (12%)
Query: 315 QMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEV-SEDDANVK 373
Q T + +Y E S + F + +T ++ CG+ V S+ A VK
Sbjct: 26048 QKTSERKY------EVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVK 26101
Query: 374 WFKNGEEIIPGPKSRYRIRVEGKKHILIIEGAT-------------KADAAEYSVM-TTG 419
W+ NG E+ K Y G + I++ T K +A++Y+ + TG
Sbjct: 26102 WYHNGVELQESSKIHYT-NTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTG 26160
Query: 420 GQSSAKLSV---DLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDR 476
G + S + P + LT E+ + + K+ +
Sbjct: 26161 GDYTTYASQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESL 26220
Query: 477 LKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVT 536
H + + AL E + TL A++ L ++T
Sbjct: 26221 SSYEHSASAE--MKSAALEEKSLEEKSTTRKIKTTLAARI------------LTKPRSMT 26266
Query: 537 VIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGV 596
V G R GEP P W R + ++ S R + + ST I + D G
Sbjct: 26267 VYEGESARFSCDTDGEPVPTVTWLRKGQ-VLSTSARHQVTTTKYKSTFEISSVQASDEGN 26325
Query: 597 YHINLKNEAGEAHASIKVKV 616
Y + ++N G+ A + +
Sbjct: 26326 YSVVVENSEGKQEAEFTLTI 26345
Score = 43.9 bits (102), Expect = 9e-04
Identities = 94/440 (21%), Positives = 160/440 (36%), Gaps = 71/440 (16%)
Query: 246 REEKKSAAFAKILDPAYQVDKGGRVRFVVELAD-PKLEVKWYKNGQEIRPSTKYIFEHKG 304
++EK+ +P +V +G RF + P+ +V WY NGQ IR S ++ + G
Sbjct: 1789 QKEKQKPDIVLYPEPV-RVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDG 1847
Query: 305 CQRILFINNCQMTDDSEYYVTAG------DEKCSTELFVREP------------------ 340
L I +C+ D E VTA + K E+ RE
Sbjct: 1848 I-HYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRPEFHVH 1906
Query: 341 --------------PIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGE-----EI 381
P+ T+ E ER+ E E + FK E
Sbjct: 1907 EPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEA 1966
Query: 382 IPGPKSRYRIRVEGKKHIL-------------IIEGATKADAAEYSV-MTTGGQSSAKLS 427
I + + R + E + +L + E KA A E + + T +LS
Sbjct: 1967 ITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELS 2026
Query: 428 VDLKPLKILTPLTDQTVNLGKEICLKCEI--SENIPGKWTKNGLPVQESDRLK-VVHKGR 484
++ KI + QTV G + + + + +W KNG+ ++ SDR+ +
Sbjct: 2027 PSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDN 2086
Query: 485 IHKLVIANALTEDEGDYVFAPDAYNVTLPAKVH---VIDPPKIILDGLDADNTVTVIAGN 541
+ +LVI + ED + A N+ H ++ ++I + + V
Sbjct: 2087 VCELVIRDVTAEDSASIMV--KAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDT 2144
Query: 542 KLRLEIPISGEPPPKAMWSRGDKAIMEGSG-RIRTE-SYPDSSTLVIDIAERDDSGVYHI 599
E S EP K W + + EG R+ ++ S L ID ++ +D +
Sbjct: 2145 MATFECETS-EPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLV 2203
Query: 600 NLKNEAGEAHASIKVKVVDF 619
+N A ++ VV+F
Sbjct: 2204 EDENVKTTAKLIVEGAVVEF 2223
Score = 43.9 bits (102), Expect = 9e-04
Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 1/79 (1%)
Query: 1059 IAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYC 1118
+ G A C V G P+PK+ W N I R+R+ G+ L+I YD G
Sbjct: 1807 LEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVK 1865
Query: 1119 CKAVNDLGTVEIECKLEVK 1137
A N G +E + KLE++
Sbjct: 1866 VTAENPEGVIEHKVKLEIQ 1884
Score = 43.9 bits (102), Expect = 9e-04
Identities = 59/286 (20%), Positives = 102/286 (35%), Gaps = 24/286 (8%)
Query: 854 GEAVNLVIPFQGKPRPELTWKKDGAEI-DKNQINIRNSETDTIIFIRKAERSHSGKYDLQ 912
G+ ++ Q KP E+ W +G E+ + ++I+ N+ + I SG Y +
Sbjct: 26083 GQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTY--R 26140
Query: 913 VKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKAD 972
+ AS D +D G E V + P A Y +
Sbjct: 26141 AVCTNYKGEAS-DYATLDVTGGDYTTYASQRRDEEVPRSVFPELTRTEA----YAVSSFK 26195
Query: 973 KKS-MEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGK 1031
K S ME + + + +TE E++ A+ +SA +
Sbjct: 26196 KTSEMEASSSVRE---VKSQMTET-----------RESLSSYEHSASAEMKSAALEEKSL 26241
Query: 1032 IYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDP 1091
K+ + A + T+P T G +A +C G P P +TW++ +
Sbjct: 26242 EEKSTTRKIKTTLAARILTKPRSMT-VYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSA 26300
Query: 1092 RYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1137
R+++ + + T EI D G Y N G E E L ++
Sbjct: 26301 RHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 26346
Score = 43.5 bits (101), Expect = 0.001
Identities = 61/263 (23%), Positives = 104/263 (39%), Gaps = 35/263 (13%)
Query: 261 AYQVDKGGRVRFVVEL-ADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDD 319
+++V G RF++ + + P EVKWY NG E++ S+K + + L I +C TDD
Sbjct: 26077 SHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCH-TDD 26135
Query: 320 SEYY------------------VTAGD-EKCSTELFVREPPIMVTKQLEDTTAYCGERVE 360
S Y VT GD +++ E P V +L T AY +
Sbjct: 26136 SGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPRSVFPELTRTEAYAVSSFK 26195
Query: 361 LECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGG 420
E+ E ++V+ K+ + R + +H + + +A +
Sbjct: 26196 KTSEM-EASSSVREVKS-------QMTETRESLSSYEH----SASAEMKSAALEEKSLEE 26243
Query: 421 QSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEI-SENIPG-KWTKNGLPVQESDRLK 478
+S+ + +ILT TV G+ C+ E +P W + G + S R +
Sbjct: 26244 KSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQ 26303
Query: 479 VVHKGRIHKLVIANALTEDEGDY 501
V I++ DEG+Y
Sbjct: 26304 VTTTKYKSTFEISSVQASDEGNY 26326
Score = 43.1 bits (100), Expect = 0.001
Identities = 41/170 (24%), Positives = 67/170 (39%), Gaps = 16/170 (9%)
Query: 464 WTKNGLPVQESDRLKVVHK-GRIHKLVIANALTEDEGDYVFAPD--------AYNVTLPA 514
W +G + KVV K L+I A D G++ + +T+ A
Sbjct: 1444 WFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEA 1503
Query: 515 KVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGS-GRI 573
H + P + + V + G++L +++ +G P P +W + I+ +I
Sbjct: 1504 VEHQVKPMFV-----EKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKI 1558
Query: 574 RTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKV-VDFPDP 622
R E + L ID DS Y N+AG KV V V+F +P
Sbjct: 1559 RIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEP 1608
Score = 43.1 bits (100), Expect = 0.001
Identities = 67/327 (20%), Positives = 116/327 (35%), Gaps = 65/327 (19%)
Query: 344 VTKQLEDTTAYCGERVELECEVSEDDAN--VKWFKNGEEIIPGPKSRYRIRVEGKKHILI 401
V+ Q+ G V+ C++ D + V W+ ++ K Y I E IL
Sbjct: 25265 VSGQIMHAVGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEK--YEITYEDGVAILY 25322
Query: 402 IEGATKADAAEY--SVMTTGGQSSAKLSVDLK---------------------------- 431
++ TK D Y V+ G+ S+ + +K
Sbjct: 25323 VKDITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLE 25382
Query: 432 -PLKILTPLTDQTVNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVV----HKGR 484
P + PL ++T +G+ + I+ + W K+G ++ D K KG
Sbjct: 25383 RPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKG- 25441
Query: 485 IHKLVIANALTEDEGDYV------FAPDAYNVTLPAKVHVIDPP---------KIILDGL 529
+++L I + T+D+ +Y + D+ L +H PP K +L
Sbjct: 25442 LYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLH--PPPTDSTLRPMFKRLLANA 25499
Query: 530 DADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIA 589
+ G + EI +SG PPP W + + + G D L I
Sbjct: 25500 ECQE------GQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDT 25553
Query: 590 ERDDSGVYHINLKNEAGEAHASIKVKV 616
+D+G Y + N AG ++V
Sbjct: 25554 LPEDTGYYRVTATNTAGSTSCQAHLQV 25580
Score = 42.7 bits (99), Expect = 0.002
Identities = 33/111 (29%), Positives = 46/111 (41%), Gaps = 5/111 (4%)
Query: 1021 KESAVIARDGKI----YKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKP 1076
+E +A +GKI +K E EAP + + + G +A V G P P
Sbjct: 2002 EEKKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDP 2061
Query: 1077 KITWMKNKVAIVDDPR-YRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLG 1126
+ W KN V I R Y + VC L IR + D + KA+N G
Sbjct: 2062 ECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAG 2112
Score = 42.4 bits (98), Expect = 0.003
Identities = 75/321 (23%), Positives = 117/321 (36%), Gaps = 33/321 (10%)
Query: 831 KEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQ-GKPRPELTWKKDGAEIDKNQINIRN 889
K +E +RI K+ +V E V+ F+ + + W KDG EI+
Sbjct: 3093 KLFVEGRDVRIRSIKKEV---QVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHK 3149
Query: 890 SETDTII---FIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGE 946
+ I FI + +S +G+Y ++ T ++ P PPQ+++ E
Sbjct: 3150 YVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTL-----YVNAPEPPQVLQ------E 3198
Query: 947 NVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEY---YF 1003
+T K A+ I + + W+ E T L G EY
Sbjct: 3199 LQPVTVQSGKPARFCAV----ISGRPQPKISWYKE-EQLLSTGFKCKFLHDGQEYTLLLI 3253
Query: 1004 RVFSENM----CGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI 1059
F E+ C D + SA ++ + +P E + P PL +T
Sbjct: 3254 EAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYP--PAIITPLQDTVTS 3311
Query: 1060 AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCC 1119
G A C V G K++W I +RM + LEI + P D GTY
Sbjct: 3312 EGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTF 3370
Query: 1120 KAVNDLGTVEIECKLEVKVIA 1140
A N +G V L ++V A
Sbjct: 3371 VASNAVGQVSSTANLSLEVQA 3391
Score = 41.2 bits (95), Expect = 0.006
Identities = 31/101 (30%), Positives = 45/101 (44%), Gaps = 7/101 (6%)
Query: 1022 ESAVIARDGKIYKNPVYEDFDFSEAPM-FTQPLVNTYAIAGYNATLNCSVRGNPKPKITW 1080
E + A+D K + N + E P+ FT+PL + G A L C V K+ W
Sbjct: 5959 EVQLTAKDFKTHANLFVK-----EPPVEFTKPLEDQTVEEGATAVLECEV-SRENAKVKW 6012
Query: 1081 MKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKA 1121
KN I+ +Y + ++ V L I +P D TY C A
Sbjct: 6013 FKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDA 6053
Score = 40.0 bits (92), Expect = 0.013
Identities = 44/211 (20%), Positives = 95/211 (45%), Gaps = 28/211 (13%)
Query: 245 RREEKKSAAFAKILDPAYQVD-------KGGRVRFVVELAD-PKLEVKWYKNGQEIRP-- 294
R EE + ++ P + + +G RF +++ P E W+ +GQ+I
Sbjct: 1396 RLEETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDY 1455
Query: 295 STKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFV--------REPPIMVTK 346
+ K + + G Q ++ + +D E+ V A + + + V + M +
Sbjct: 1456 THKVVIKEDGTQSLIIVP-ATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVE 1514
Query: 347 QLEDTTAYCGERVELECEVSED-DANVKWFKNGEEIIPGPKSRY-RIRVEGKK--HILII 402
+L++ G R+E++ + + + ++ W KN + I+P +Y +IR+EG K L I
Sbjct: 1515 KLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVP---HKYPKIRIEGTKGEAALKI 1571
Query: 403 EGATKADAAEY--SVMTTGGQSSAKLSVDLK 431
+ D+A Y + + G+ + + V+++
Sbjct: 1572 DSTVSQDSAWYTATAINKAGRDTTRCKVNVE 1602
Score = 40.0 bits (92), Expect = 0.013
Identities = 96/465 (20%), Positives = 165/465 (35%), Gaps = 92/465 (19%)
Query: 20 EEPSKEKEAGTTPAKDWTLVETPPGEEQAKQNANSQLSILFIEKPQGGTVKVGEDITFIA 79
E S + + + K L E E+ + + L+ + KP+ TV GE F
Sbjct: 26218 ESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSC 26277
Query: 80 KVKAEDLLRKPTIKWF-KGKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAG 138
E + PT+ W KG+ + S + +H ++ TFE+ ++A D G
Sbjct: 26278 DTDGEPV---PTVTWLRKGQ---VLSTSARHQVTTTKYKS-----TFEISSVQASDE--G 26324
Query: 139 NYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRRE 198
NY V + F L + ++ T + K S E + + E + +
Sbjct: 26325 NYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVK-SPEPRVKSPE----AVKSPKR 26379
Query: 199 VKQQEEEPQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKIL 258
VK E V KP+ EK+ + K + ++ E K A
Sbjct: 26380 VKSPEPSHPKAVSP--TETKPTPTEKVQH----LPVSAPPKITQFLKAEASKEIA----- 26428
Query: 259 DPAYQVDKGGRVRFVVELADPKL-EVKWYKNGQEIRPSTKYIFEHKGCQRI-LFINNCQM 316
++ VVE + + EV WYK+G++++ + + F + L INN
Sbjct: 26429 ----------KLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTE 26478
Query: 317 TDDSEYY---------------------------------VTAGDEKCSTELFVR--EP- 340
+D EY D+K + R EP
Sbjct: 26479 SDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPK 26538
Query: 341 --------PIMVTKQLEDTTAYCGERVELECEVS-EDDANVKWFKNGEEIIPGPKSRYRI 391
P++VT L+DTT + + + E W K+G+ I G K Y++
Sbjct: 26539 APEPISSKPVIVT-GLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGK--YKL 26595
Query: 392 RVEGKKHILIIEGATKADAAEY--SVMTTGGQSSAKLSVDLKPLK 434
+ L I +D+ Y +V + G S+ + +K +K
Sbjct: 26596 SEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIK 26640
Score = 39.7 bits (91), Expect = 0.017
Identities = 25/98 (25%), Positives = 37/98 (37%)
Query: 1039 EDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSN 1098
+ F AP T + + G N +V+ P ++ W N V + + + +
Sbjct: 26061 QPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNT 26120
Query: 1099 QGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
GV TLEI D GTY N G L+V
Sbjct: 26121 SGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDV 26158
Score = 39.3 bits (90), Expect = 0.022
Identities = 58/327 (17%), Positives = 107/327 (32%), Gaps = 45/327 (13%)
Query: 854 GEAVNLVIPFQGKPRPELTWKKDGAEIDKN---QINIRNSETDTIIFIRKAERSHSGKYD 910
G+ + G+P PE W DG +I + ++ I+ T ++I + A S SG++
Sbjct: 1425 GQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIV-PATPSDSGEWT 1483
Query: 911 L--QVKVDKFVETASIDIQIIDRPGPPQIV----------------KIEDVWGENVALTW 952
+ Q + + + + ++ ++ P V K+ N + W
Sbjct: 1484 VVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVW 1543
Query: 953 TPPKD------------DGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNE 1000
D +G I + W+T ++ T + E
Sbjct: 1544 LKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATA-INKAGRDTTRCKVNVE 1602
Query: 1001 YYFR--------VFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQP 1052
F + E A E + + ++ D + + P F +
Sbjct: 1603 VEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKK 1662
Query: 1053 LVNTYAIAGYNATLNCSVR--GNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPS 1110
L + A C + G+P + W+ + + R RM + G C+L+
Sbjct: 1663 LTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAY 1722
Query: 1111 PYDGGTYCCKAVNDLGTVEIECKLEVK 1137
D G C+A N GT L VK
Sbjct: 1723 SRDSGIITCRATNKYGTDHTSATLIVK 1749
Score = 38.9 bits (89), Expect = 0.028
Identities = 44/162 (27%), Positives = 69/162 (42%), Gaps = 13/162 (8%)
Query: 279 PKLEVKWYKNGQEIRPST--KYIFEHKGCQRILFINNCQMTDDSEYYVTA----GDEKCS 332
P EV W+++GQ I ST + L I + Y + A G +
Sbjct: 33 PVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKATNGSGQATST 92
Query: 333 TELFVR---EPPIMVTKQLEDTTAYCGERVELECEVSE-DDANVKWFKNGEEIIPGPKSR 388
EL V+ PP V ++L+ T G +V L+ V+ VK++++G EI
Sbjct: 93 AELLVKAETAPPNFV-QRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEI--QSSLD 149
Query: 389 YRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDL 430
++I EG + L+I A D+ YSV T A + +L
Sbjct: 150 FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAEL 191
Score = 38.5 bits (88), Expect = 0.037
Identities = 75/342 (21%), Positives = 130/342 (38%), Gaps = 50/342 (14%)
Query: 316 MTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDA-NVKW 374
MTD S AG + + F+ +P +V K +E G V C+V + +V W
Sbjct: 1018 MTDTSLTEEQAGPGEPAAPYFITKP--VVQKLVE------GGSVVFGCQVGGNPKPHVYW 1069
Query: 375 FKNGEEIIPGPKSRYRIRVEGKKHI----LIIEGATKADAAEYSVMTTG--GQSSAKLSV 428
K+G + G YR +V K L+I DA EY+++ G++SA S+
Sbjct: 1070 KKSGVPLTTG----YRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125
Query: 429 DLKPLKILTPLTDQTVNLGKEICL---KCEISENIPGKWTKNGLPVQESDRLKVVHKGRI 485
+ L + Q + ++ + ++ E PG + + + ++ K
Sbjct: 1126 LEEADYELLMKSQQEMLYQTQVTAFVQEPKVGETAPG-FVYSEYEKEYEKEQALIRKKMA 1184
Query: 486 HKLVIANALTEDEGDYVFAPDA----------YNVTLPAKVHVIDPPKIILD-------- 527
V+ ED+ ++ + + TL + K+ +D
Sbjct: 1185 KDTVVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVE 1244
Query: 528 -GLDAD-NTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS-STL 584
G D+ ++ G + +SG P PK W + K I G R + + D ++L
Sbjct: 1245 SGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGE-RYQMDFLQDGRASL 1303
Query: 585 VIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAP 626
I + +D G+Y N G A S K+ V P AP
Sbjct: 1304 RIPVVLPEDEGIYTAFASNIKGNAICSGKLYV-----EPAAP 1340
Score = 38.1 bits (87), Expect = 0.048
Identities = 38/173 (21%), Positives = 68/173 (39%), Gaps = 11/173 (6%)
Query: 337 VREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGK 396
++E M+ L DT + G+ V L ++ +F+N +++P + +++ +
Sbjct: 4430 IKEDGPMIHTPLVDTVSEEGDIVHLTTSITNAKEVNWYFEN--KLVPSDE-KFKCLQDQN 4486
Query: 397 KHILIIEGATKAD-AAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVN-----LGKEI 450
+ L+I+ D EY S L +K P+ + + LG
Sbjct: 4487 TYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLA 4546
Query: 451 CLKCEISE--NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 501
CEI N+ +W K G + ESD+ + I L I D G+Y
Sbjct: 4547 KFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEY 4599
Score = 38.1 bits (87), Expect = 0.048
Identities = 27/98 (27%), Positives = 41/98 (41%), Gaps = 3/98 (3%)
Query: 1042 DFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGV 1101
D + PMF + L N G + V G P P + W K+ + P + ++G+
Sbjct: 25485 DSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEII-HEGL 25543
Query: 1102 --CTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1137
L IR P D G Y A N G+ + L+V+
Sbjct: 25544 DYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 25581
Score = 37.7 bits (86), Expect = 0.063
Identities = 26/83 (31%), Positives = 34/83 (40%), Gaps = 5/83 (6%)
Query: 264 VDKGGRVRFVVELAD-PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 322
V G VRF + P KW +G EI+ Y E +L I NC D EY
Sbjct: 11217 VKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEY 11276
Query: 323 YVT----AGDEKCSTELFVREPP 341
+T AG + + L V + P
Sbjct: 11277 QITVSNAAGSKTVAVHLTVLDVP 11299
Score = 37.7 bits (86), Expect = 0.063
Identities = 19/65 (29%), Positives = 31/65 (47%)
Query: 1077 KITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
++TW + + +Y + GV L ++ + D GTY CK VND G +L V
Sbjct: 25294 QVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFV 25353
Query: 1137 KVIAQ 1141
K + +
Sbjct: 25354 KGVRE 25358
Score = 37.0 bits (84), Expect = 0.11
Identities = 25/94 (26%), Positives = 40/94 (42%), Gaps = 1/94 (1%)
Query: 1047 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYR-MFSNQGVCTLE 1105
P+F V+ + G A + V G P P+ W + IV+D ++ + G +L
Sbjct: 1411 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLI 1470
Query: 1106 IRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVI 1139
I +P D G + A N G I L V+ +
Sbjct: 1471 IVPATPSDSGEWTVVAQNRAGRSSISVILTVEAV 1504
Score = 36.6 bits (83), Expect = 0.14
Identities = 53/275 (19%), Positives = 95/275 (34%), Gaps = 51/275 (18%)
Query: 340 PPIMVTKQLEDTTAYCGERVELECEVSE-DDANVKWFKNGEEIIPGPKSRYRIRVEGKKH 398
PP +V+ L++ T GE V LEC +S V W++ +I ++I +
Sbjct: 896 PPTLVSG-LKNVTVIEGESVTLECHISGYPSPTVTWYREDYQI--ESSIDFQITFQSGIA 952
Query: 399 ILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISE 458
L+I A D+ + T VN + C ++
Sbjct: 953 RLMIREAFAEDSGRF--------------------------TCSAVNEAGTVSTSCYLAV 986
Query: 459 NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIAN-ALTEDEGDYVFAPDAYNVTLPAKVH 517
+ ++ K V E + +V+ + +LTE++ Y +T P
Sbjct: 987 QVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQK 1046
Query: 518 VIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSG-RIRTE 576
+++ G + + G P P W + + G ++
Sbjct: 1047 LVE-------------------GGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYN 1087
Query: 577 SYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHAS 611
LVI + DD+G Y I ++N+ GE AS
Sbjct: 1088 KQTGECKLVISMTFADDAGEYTIVVRNKHGETSAS 1122
Score = 36.2 bits (82), Expect = 0.18
Identities = 45/250 (18%), Positives = 92/250 (36%), Gaps = 31/250 (12%)
Query: 873 WKKDGAEIDKN-QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDR 931
W KDG EI + + +I+ I+ I+KA+ G+Y DK +++ ++I
Sbjct: 5389 WFKDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKV 5448
Query: 932 PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSAT 991
P V++ + + + P G + G + T++
Sbjct: 5449 EKPLYGVEVFVGETAHFEIELSEPDVHGQWKLKGQPL-------------------TASP 5489
Query: 992 ITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQ 1051
E++ + + + G++ + + +A A + K+ + P+ +F
Sbjct: 5490 DCEIIEDGKKHILILHNCQLGMTGEVSFQAANAKSAANLKVKELPL----------IFIT 5539
Query: 1052 PLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSP 1111
PL + A C V PK W+K I D R+ + + ++ I+ +
Sbjct: 5540 PLSDVKVFEKDEAKFECEVSREPK-TFRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAF 5598
Query: 1112 YDGGTYCCKA 1121
D Y +A
Sbjct: 5599 EDEAKYMFEA 5608
Score = 36.2 bits (82), Expect = 0.18
Identities = 39/146 (26%), Positives = 56/146 (38%), Gaps = 11/146 (7%)
Query: 276 LADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTEL 335
L PK V W K Q ++ + + FE IL IN C +D Y +TA +
Sbjct: 14785 LGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARN------- 14837
Query: 336 FVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEG 395
V E ++T Q+ D ++ + EVS D W E P S Y + +
Sbjct: 14838 IVGEVGDVITIQVHDIPGPPTGPIKFD-EVSSDFVTFSW-DPPENDGGVPISNYVVEMRQ 14895
Query: 396 KKHILIIEGATKADAAEYSV--MTTG 419
+E AT Y +TTG
Sbjct: 14896 TDSTTWVELATTVIRTTYKATRLTTG 14921
Score = 35.8 bits (81), Expect = 0.24
Identities = 25/91 (27%), Positives = 42/91 (46%), Gaps = 1/91 (1%)
Query: 534 TVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS-STLVIDIAERD 592
+V V+ G+ E ISG P P+ W R + I + S+ D + L I +
Sbjct: 14 SVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKA 73
Query: 593 DSGVYHINLKNEAGEAHASIKVKVVDFPDPP 623
+SG Y + N +G+A ++ ++ V PP
Sbjct: 74 NSGRYSLKATNGSGQATSTAELLVKAETAPP 104
Score = 35.8 bits (81), Expect = 0.24
Identities = 23/89 (25%), Positives = 34/89 (38%), Gaps = 2/89 (2%)
Query: 536 TVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSG--RIRTESYPDSSTLVIDIAERDD 593
T G +R + I+ P P W + + I G + ES L I+ DD
Sbjct: 25395 TAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDD 25454
Query: 594 SGVYHINLKNEAGEAHASIKVKVVDFPDP 622
Y + +N+ GE K+ V P P
Sbjct: 25455 DAEYTVVARNKYGEDSCKAKLTVTLHPPP 25483
Score = 35.0 bits (79), Expect = 0.41
Identities = 23/91 (25%), Positives = 37/91 (40%)
Query: 1047 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEI 1106
P F Q L + G L V G P P + + ++ I +++ + +L I
Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLI 163
Query: 1107 RKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1137
+ P D GTY A N +G +L V+
Sbjct: 164 AEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 35.0 bits (79), Expect = 0.41
Identities = 27/90 (30%), Positives = 39/90 (43%), Gaps = 4/90 (4%)
Query: 1047 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEI 1106
P FT L + A+ TL C V + K W K+ IV P+Y + ++ L+I
Sbjct: 5358 PYFTVKLHDKTAVEKDEITLKCEVSKDVPVK--WFKDGEEIVPSPKYSIKADGLRRILKI 5415
Query: 1107 RKPSPYDGGTYCCKAVND--LGTVEIECKL 1134
+K D G Y C D V +E +L
Sbjct: 5416 KKADLKDKGEYVCDCGTDKTKANVTVEARL 5445
Score = 33.9 bits (76), Expect = 0.91
Identities = 27/119 (22%), Positives = 51/119 (42%), Gaps = 11/119 (9%)
Query: 393 VEGKKHILIIEGATKADAAEYSVM-------TTGGQSSAKLSVDLKPLKILTPLTDQTVN 445
VE KK + + T + V+ T + A + + + P +++ L + TV
Sbjct: 850 VEVKKEVGVSITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVI 909
Query: 446 LGKEICLKCEISENIPGK---WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 501
G+ + L+C IS P W + ++ S ++ + I +L+I A ED G +
Sbjct: 910 EGESVTLECHIS-GYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRF 967
Score = 33.5 bits (75), Expect = 1.2
Identities = 35/140 (25%), Positives = 63/140 (45%), Gaps = 11/140 (7%)
Query: 792 KTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIR 851
+ K TI + +KA N +G + + +LVK PP + L+ +R
Sbjct: 62 RAKLTIPAVTKANSGRYSLKATNGSGQATS---TAELLVKAETAPPNF--VQRLQSMTVR 116
Query: 852 RVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTI--IFIRKAERSHSGKY 909
+ G V L + G P P + + +DGAEI ++ ++ + S+ + + I +A SG Y
Sbjct: 117 Q-GSQVRLQVRVTGIPTPVVKFYRDGAEI-QSSLDFQISQEGDLYSLLIAEAYPEDSGTY 174
Query: 910 DLQV--KVDKFVETASIDIQ 927
+ V + TA + +Q
Sbjct: 175 SVNATNSVGRATSTAELLVQ 194
Score = 33.5 bits (75), Expect = 1.2
Identities = 105/543 (19%), Positives = 203/543 (37%), Gaps = 71/543 (13%)
Query: 3 EPTKKEENEVP-APAPPPEEPSKEKEAGTTPAKDWTLVETPPGEEQAKQNANSQLSILFI 61
+P K EE P P PPE PS E +L + P K + S+++ +I
Sbjct: 24007 KPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRP-----KDDGGSRVTGYYI 24061
Query: 62 EKPQGGTVK-VGEDITFIAKVKAEDLLRKPTIKWF------KGKWMDLASKAGKHLQLKE 114
E+ + T K V + T I P ++ + S A + + K+
Sbjct: 24062 ERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKD 24121
Query: 115 TFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSA 174
F++ S+ E+ I DS + E E G +
Sbjct: 24122 PFDKPSQPGELEILSISK------------------DSVTLQWEKPECDGGKEILGYWVE 24163
Query: 175 FKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLKNAKPSEYEKIAF---QYGI 231
+++SG+ ++ K++ ++ Q + LL+ +EYE F + G+
Sbjct: 24164 YRQSGDSAW------------KKSNKERIKDKQFTIGGLLE---ATEYEFRVFAENETGL 24208
Query: 232 TDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQE 291
+ R +K + ++ D ++ + ++ + + P ++KWY+ G+E
Sbjct: 24209 SRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQI-VGRPLPDIKWYRFGKE 24267
Query: 292 IRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTA----GDEKCSTELFVREPPIMVT-- 345
+ S KY G L + + D+ Y A G+ + S++L ++ P
Sbjct: 24268 LIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGY 24327
Query: 346 KQLEDTTAYCGERVELE-CEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEG 404
E G + L + + WF +G++++ ++ E H+++
Sbjct: 24328 PLKEKYYGAVGSTLRLHVMYIGRPVPAMTWF-HGQKLLQNSENITIENTEHYTHLVMKNV 24386
Query: 405 ATKADAAEYSVMTTG--GQSSAKLSVDL--KPLKILTPLTDQTVNLGKEICLKCEISENI 460
K A +Y V + G A L V++ KP K P+ + + L + + +
Sbjct: 24387 QRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEAL-LKNSAVISWKPPADD 24445
Query: 461 PGKWTKNGL----PVQESDRLKVVHKG-RIHKLVIANALTEDEGDY--VFAPDAYNVTLP 513
G W N + +E ++V + I N LTE+ G Y V A + + ++ P
Sbjct: 24446 GGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVN-LTENAGYYFRVSAQNTFGISDP 24504
Query: 514 AKV 516
+V
Sbjct: 24505 LEV 24507
Score = 33.5 bits (75), Expect = 1.2
Identities = 43/147 (29%), Positives = 59/147 (40%), Gaps = 10/147 (6%)
Query: 279 PKLEVKWYKNGQE-IRPSTKY-IFEHKGCQRILFINNCQMTDDSEYYVTA----GDEKCS 332
PK VKWY+ G+E I KY I E KG L I + D + Y V A G +
Sbjct: 24650 PKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGT 24709
Query: 333 TELFVREP-PIMVTKQLED---TTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSR 388
L V P I + K LE A GE V ++ S V ++ G+++I
Sbjct: 24710 ASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHY 24769
Query: 389 YRIRVEGKKHILIIEGATKADAAEYSV 415
I ++ G + DA Y V
Sbjct: 24770 QVIVTRSFTSLVFPNGVERKDAGFYVV 24796
Score = 33.1 bits (74), Expect = 1.5
Identities = 21/96 (21%), Positives = 41/96 (42%), Gaps = 3/96 (3%)
Query: 847 QTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ---INIRNSETDTIIFIRKAER 903
Q+ + G G P PE++W +DG I + + I S+ + I +
Sbjct: 13 QSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTK 72
Query: 904 SHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVK 939
++SG+Y L+ T++ ++ + PP V+
Sbjct: 73 ANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQ 108
Score = 33.1 bits (74), Expect = 1.5
Identities = 21/93 (22%), Positives = 39/93 (41%), Gaps = 1/93 (1%)
Query: 538 IAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVY 597
+ G R ++ + G P P+ W + I+ + +L+I A DSG +
Sbjct: 1423 LEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEW 1482
Query: 598 HINLKNEAGEAHASIKVKVVDFPDPPVAPTVTE 630
+ +N AG + S+ + V+ + V P E
Sbjct: 1483 TVVAQNRAGRSSISV-ILTVEAVEHQVKPMFVE 1514
Score = 33.1 bits (74), Expect = 1.5
Identities = 19/61 (31%), Positives = 27/61 (44%), Gaps = 1/61 (1%)
Query: 1064 ATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVN 1123
AT C P K+ W K+ + + + +YRM S++ V L I D Y C V
Sbjct: 2146 ATFECET-SEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVE 2204
Query: 1124 D 1124
D
Sbjct: 2205 D 2205
Score = 32.3 bits (72), Expect = 2.6
Identities = 28/116 (24%), Positives = 51/116 (43%), Gaps = 8/116 (6%)
Query: 105 KAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTG 164
KAG+ + + S Y ++I++ + G Y C+ + + SC+ L V
Sbjct: 4564 KAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV----- 4618
Query: 165 TTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLKNAKPS 220
T P + + E E+ +L++R +EEEP+V+ +L K KP+
Sbjct: 4619 TVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKR---PEEEEPKVEPKKLEKVKKPA 4671
Score = 32.3 bits (72), Expect = 2.6
Identities = 27/117 (23%), Positives = 42/117 (35%), Gaps = 9/117 (7%)
Query: 1004 RVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYN 1063
R+ N C L ++A + E G + E +FT+ L N
Sbjct: 6123 RILVINKCLLDDEAEYSCEVRTARTSGMLTV--------LEEEAVFTKNLANIEVSETDT 6174
Query: 1064 ATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCK 1120
L C V P ++ W K I++ RY + + L I+ D G Y C+
Sbjct: 6175 IKLVCEV-SKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNCR 6230
Score = 32.3 bits (72), Expect = 2.6
Identities = 16/45 (35%), Positives = 22/45 (48%), Gaps = 3/45 (6%)
Query: 836 PPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI 880
PP+ +P + K Y VGE V + P P +TW K G +I
Sbjct: 25384 PPEFTLPLYNKTAY---VGENVRFGVTITVHPEPHVTWYKSGQKI 25425
Score = 32.0 bits (71), Expect = 3.4
Identities = 27/97 (27%), Positives = 39/97 (40%), Gaps = 5/97 (5%)
Query: 249 KKSAAFAKILDPAYQVDKGGRVRFVVELAD-PKLEVKWYKNGQEIRPSTKYIFEHKGCQR 307
K++A K +V G +F E+ P + +W+K G+EI S K
Sbjct: 4525 KRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYIS 4584
Query: 308 ILFINNCQMTDDSEYYVTAGDE----KCSTELFVREP 340
L I Q+ D EY A +E C+ L V P
Sbjct: 4585 SLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVP 4621
Score = 31.6 bits (70), Expect = 4.5
Identities = 26/88 (29%), Positives = 33/88 (37%), Gaps = 4/88 (4%)
Query: 1052 PLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSP 1111
PL + I G A L C V + W N I D R + L I +
Sbjct: 2404 PLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHA 2463
Query: 1112 YDGGTYCCKAVNDLGTVEIECKLEVKVI 1139
D G Y K + +G VE C L V+ I
Sbjct: 2464 SDEGPY--KLI--VGRVETNCNLSVEKI 2487
Score = 31.2 bits (69), Expect = 5.9
Identities = 23/93 (24%), Positives = 32/93 (34%)
Query: 1045 EAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTL 1104
EAP L + G A C ++ + +TW I + R + N + L
Sbjct: 3487 EAPKIFLHLQDVTVKCGDTAQFLCVLKDDSFIDVTWTHEGAKIEESERLKQSQNGNIQFL 3546
Query: 1105 EIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1137
I D G Y C ND G L V+
Sbjct: 3547 TICNVQLVDQGLYSCIVHNDCGERTTSAVLSVE 3579
Score = 31.2 bits (69), Expect = 5.9
Identities = 15/66 (22%), Positives = 30/66 (45%), Gaps = 1/66 (1%)
Query: 262 YQVDKGGRVRFVVE-LADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDS 320
Y + G ++ + + P+ + W K+G+ ++ +T+ E +L I D
Sbjct: 18016 YSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFG 18075
Query: 321 EYYVTA 326
+Y VTA
Sbjct: 18076 KYTVTA 18081
>gi|110349713 titin isoform novex-1 [Homo sapiens]
Length = 27051
Score = 288 bits (738), Expect = 2e-77
Identities = 218/774 (28%), Positives = 346/774 (44%), Gaps = 70/774 (9%)
Query: 272 FVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKC 331
F +L+ K VKWY+NG+EI+ KY FE G L I +C++ D+ EY D K
Sbjct: 6470 FSCQLSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYACGVEDRKS 6529
Query: 332 STELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRI 391
LFV E P+ + + +D G V E+++D V+W +N ++ G K +++
Sbjct: 6530 RARLFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQWLRNNMVVVQGDK--HQM 6587
Query: 392 RVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEIC 451
EGK H L I D EY + ++ AKL + P KI T D V++GK +
Sbjct: 6588 MSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLELAAAP-KIKTADQDLVVDVGKPLT 6646
Query: 452 LKC--EISENIPGKWTKNGLPV----------QESDRL---KVVHKGRIHKLVIANALTE 496
+ + +W K P+ Q S R+ K KGR +K+V+ N +
Sbjct: 6647 MVVPYDAYPKAEAEWFKENEPLSTKTIDTTAEQTSFRILEAKKGDKGR-YKIVLQNKHGK 6705
Query: 497 DEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPK 556
EG + VID P + + + T T L E P++
Sbjct: 6706 AEGFI-------------NLKVIDVPGPVRN---LEVTETFDGEVSLAWEEPLTDGGSKI 6749
Query: 557 AMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG-----EAHAS 611
+ + I + + T+ V + + ++ ++ +N G E
Sbjct: 6750 IGYVVERRDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNP 6809
Query: 612 IKVKV-VDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLN 670
++ + D P PP+ T+T+V + WEPP YDGG+ I Y IE + K S RW
Sbjct: 6810 VEARSKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAM 6869
Query: 671 FDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV----PLAVTSPPTLLTV 726
++ + ++EG Y R+ A N IG+ KPS + PFV P+ SPP LT
Sbjct: 6870 TVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAAT-PFVKVADPIERPSPPVNLTS 6928
Query: 727 DSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVAN 786
T ++V ++W PP G + + GY++E C EG ++WI N
Sbjct: 6929 SDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGK------------------DNWIRCN 6970
Query: 787 KDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLK 846
L+ + + +TGL K RV A N AG S+P P+ + P + + K
Sbjct: 6971 MKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSA-FK 7029
Query: 847 QTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDK-NQINIRNSETDTIIFIRKAERSH 905
V + +++P G PRP TW ++ +++ ++ + I +ERS
Sbjct: 7030 DGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSD 7089
Query: 906 SGKYDLQVKVDKFVETAS--IDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAI 963
G Y L K++ V+T S ID+ +I RP P+ +K D+ ++V LTW PP DDG + +
Sbjct: 7090 KGIYTL--KLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPL 7147
Query: 964 TGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDA 1017
TGY ++K + W V++ T+ +LV G EY F+V + N CG E A
Sbjct: 7148 TGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 7201
Score = 278 bits (711), Expect = 2e-74
Identities = 166/521 (31%), Positives = 269/521 (51%), Gaps = 35/521 (6%)
Query: 511 TLPAKVHV---IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIM 567
TLP V I+PP+I LD D V + A LRL + I G P P+ W + + +
Sbjct: 18719 TLPGSVVAQERIEPPEIELDA-DLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILT 18777
Query: 568 EGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT 627
+ R + E + LVID R DSG Y++ L+N +G A + V+V+D P PV T
Sbjct: 18778 D---RAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLT 18834
Query: 628 VTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEG 687
+ EV D ++WEPP DGG+ I Y +E+++ + + + C +TTF + + EG
Sbjct: 18835 IREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNN-CTKTTFRIENLQEG 18893
Query: 688 VAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAA 747
+Y R+ A N GI P+ + P PP +T+ VT T T++W P+ G +
Sbjct: 18894 CSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGS 18953
Query: 748 GLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIF 807
+ GYV+E +GS E W + + + TI+GL +
Sbjct: 18954 KITGYVVEMQTKGS------------------EKWSTCTQ--VKTLEATISGLTAGEEYV 18993
Query: 808 VRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKP 867
RV AVN G S+P+ P++ ++I P + +P H T+ + E + + +PF+G+P
Sbjct: 18994 FRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFH---TFNVKAREQLKIDVPFKGRP 19050
Query: 868 RPELTWKKDGAEI-DKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDI 926
+ + W+KDG + + ++N+ +S+T T + I++A + G Y+L V T I I
Sbjct: 19051 QATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITI 19110
Query: 927 QIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYH 986
++DRPGPP ++I++V +++ ++W PP+ DG I+ Y ++K + S W V +
Sbjct: 19111 IVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVA 19170
Query: 987 RTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIA 1027
RTS I L G+EY FRV +EN G S + ++ SAV+A
Sbjct: 19171 RTSIKIVRLTTGSEYQFRVCAENRYGKS---SYSESSAVVA 19208
Score = 270 bits (691), Expect = 4e-72
Identities = 179/588 (30%), Positives = 288/588 (48%), Gaps = 53/588 (9%)
Query: 438 PLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQ------ESDRLKVVHKGRIHKLVIA 491
P+ D + I KC++S G+WT P E ++L H+ I
Sbjct: 16489 PIYDGGCEIQGYIVEKCDVSV---GEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAIN 16545
Query: 492 NALTEDEGDYVFAPDAYNVTLPAKVHV---IDPPKIILDGLDADNTVTVIAGNKLRLEIP 548
A + D +P + V ++ P I LD L+ + + AG LRL +P
Sbjct: 16546 KAGVGEHAD-----------VPGPIIVEEKLEAPDIDLD-LELRKIINIRAGGSLRLFVP 16593
Query: 549 ISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEA 608
I G P P+ W + D I + + T S+ ++LV+D R DSG Y + L+N +G
Sbjct: 16594 IKGRPTPEVKWGKVDGEIRDAAIIDVTSSF---TSLVLDNVNRYDSGKYTLTLENSSGTK 16650
Query: 609 HASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMR 668
A + V+V+D P PPV VTE+ D + WEPP DGGS I Y +E+++ +
Sbjct: 16651 SAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAA 16710
Query: 669 LNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDS 728
+ + C + +++ ++ EG +Y R+ A N GI P+ + P V PP +TVD
Sbjct: 16711 VVTN-CHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDD 16769
Query: 729 VTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKD 788
VT +V++ W P+H G + + Y++E AK S++ E A
Sbjct: 16770 VTRNSVSLSWTKPEHDGGSKIIQYIVE------MQAKHSEKWSECA-------------- 16809
Query: 789 LIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQT 848
+ + IT L + RV AVN G S+P+ + PI+ K+++ P + + +
Sbjct: 16810 RVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDV---KPAFSS 16866
Query: 849 YIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDK-NQINIRNSETDTIIFIRKAERSHSG 907
Y +VG+ + + +P G+P+P +TW KDG + + +IN+ +S T + I++ + G
Sbjct: 16867 YSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGG 16926
Query: 908 KYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWGENVALTWTPPKDDGNAAITGY 966
+Y + V +TASI+I +D+P PP+ VK +DV E++ L+W PP G IT Y
Sbjct: 16927 QYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNY 16986
Query: 967 TIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLS 1014
+QK D + W V RT+ +T+L G EY FR+F+EN G S
Sbjct: 16987 IVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQS 17034
Score = 259 bits (662), Expect = 1e-68
Identities = 158/580 (27%), Positives = 280/580 (48%), Gaps = 37/580 (6%)
Query: 519 IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESY 578
++ P++ LD + + V AG R+ IP G P P+ WSR + E + +++ E
Sbjct: 17647 LEAPELDLDS-ELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEG---EFTDKVQIEKG 17702
Query: 579 PDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIM 638
+ + L ID +R+D+G Y + L+N +G A + VKV+D P PP V EV D +
Sbjct: 17703 VNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFL 17762
Query: 639 NWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVN 698
WEPP DGG+ + Y I++++ + ++ C +T+F+ + + EG Y R+ A N
Sbjct: 17763 VWEPPIIDGGAKVKNYVIDKRESTRKAYANVS-SKCSKTSFKVENLTEGAIYYFRVMAEN 17821
Query: 699 AIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCF 758
G+ P SPP +T+ V+ T+ ++ W P+H G + + GYV+E
Sbjct: 17822 EFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQP 17881
Query: 759 EGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGA 818
+G+ E W + + + +TGL + + RVKA N G
Sbjct: 17882 KGT------------------EKWSIVAESKV--CNAVVTGLSSGQEYQFRVKAYNEKGK 17921
Query: 819 SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGA 878
S+P+ P++ K++ P +++P + TY + GE + + IP G+PRP ++W KDG
Sbjct: 17922 SDPRVLGVPVIAKDLTIQPSLKLPFN---TYSIQAGEDLKIEIPVIGRPRPNISWVKDGE 17978
Query: 879 EIDK-NQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPP-Q 936
+ + ++N+ + T T++ I++ + GKY + T ++ + ++++PGPP
Sbjct: 17979 PLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVG 18038
Query: 937 IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELV 996
V+ ++V + V ++W PP G I+ Y ++K D + W V RT+ IT+L
Sbjct: 18039 PVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTIKITKLK 18098
Query: 997 IGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNT 1056
G EY FR+F+EN G S A + ++ ++ +K P F + Q LV
Sbjct: 18099 TGTEYQFRIFAENRYGKS--APLDSKAVIVQYP---FKEPGPPGTPFVTSISKDQMLVQW 18153
Query: 1057 YAIAGYNAT--LNCSVRGNPKPKITWMKNKVAIVDDPRYR 1094
+ T + + K I W+K + D +++
Sbjct: 18154 HEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFK 18193
Score = 248 bits (632), Expect = 3e-65
Identities = 149/496 (30%), Positives = 252/496 (50%), Gaps = 30/496 (6%)
Query: 521 PPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPD 580
PP+I LD D VT+ A LRL +PI G P P+ W+R ++ + T SY
Sbjct: 15485 PPEIELDA-DLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESLDKASIESTSSY-- 15541
Query: 581 SSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNW 640
+ L++ R DSG Y + ++N +G A + V+V+D P PP V EV + W
Sbjct: 15542 -TLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTW 15600
Query: 641 EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAI 700
+PP DGGS I Y +E+++ + + + C +T+++ ++ EG +Y R+ A N
Sbjct: 15601 DPPLLDGGSKIKNYIVEKRESTRKAYSTVATN-CHKTSWKVDQLQEGCSYYFRVLAENEY 15659
Query: 701 GISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEG 760
GI P+ + PP +T+ VT +V++ W P+H G + + GY++E +G
Sbjct: 15660 GIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKG 15719
Query: 761 STSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASE 820
S + W A + T+ TITGL + RV A N G S+
Sbjct: 15720 S------------------DKW--ATCATVKVTEATITGLIQGEEYSFRVSAQNEKGISD 15759
Query: 821 PKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI 880
P+ S P++ K+++ PP ++ L T+ GE + + +PF G+P P +TW KD +
Sbjct: 15760 PRQLSVPVIAKDLVIPPAFKL---LFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPL 15816
Query: 881 DK-NQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IV 938
+ ++N ++E ++++ I+ A R G Y +++ ++++ ++D+PGPP V
Sbjct: 15817 KQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPV 15876
Query: 939 KIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIG 998
K+++V +++ L+W PPK DG ++I Y ++K D + W V RT+ L G
Sbjct: 15877 KMDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVSATVARTTIKACRLKTG 15936
Query: 999 NEYYFRVFSENMCGLS 1014
EY FR+ +EN G S
Sbjct: 15937 CEYQFRIAAENRYGKS 15952
Score = 244 bits (624), Expect = 3e-64
Identities = 156/511 (30%), Positives = 243/511 (47%), Gaps = 35/511 (6%)
Query: 518 VIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRG--DKAIMEGSGRIRT 575
+++PP+I LD V V AG +RL + G P PK W + D + +G +
Sbjct: 12228 ILEPPEIDLDA-SMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKG----QV 12282
Query: 576 ESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDW 635
+ + LVI + RDDSG Y + L N AGE + V+V+D P P V++V
Sbjct: 12283 DLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTS 12342
Query: 636 CIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIF 695
C ++W PP DGGS + Y +E+++ W + ++ K+T+F ++ G Y R+
Sbjct: 12343 CHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEV-KKTSFHVTNLVPGNEYYFRVT 12401
Query: 696 AVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGY 752
AVN G P+ +P + PL+ PP L V +T + T+ W PP G A +DGY
Sbjct: 12402 AVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGY 12461
Query: 753 VLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKA 812
+ Y E + PA+ W ++ +TGL K RV A
Sbjct: 12462 ITSYREE----------------EQPADRW--TEYSVVKDLSLVVTGLKEGKKYKFRVAA 12503
Query: 813 VNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELT 872
NA G S P+ KE + PPKI +P + + G+ + + GKP P
Sbjct: 12504 RNAVGVSLPREAEGVYEAKEQLLPPKILMPEQI----TIKAGKKLRIEAHVYGKPHPTCK 12559
Query: 873 WKKDGAE-IDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDR 931
WKK E + + + + +++ +I+ I+ R SG Y L + +T I + ++D
Sbjct: 12560 WKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDA 12619
Query: 932 PGPPQ-IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSA 990
PGPPQ I D+ + +L+W P +DG + IT Y ++K D +W T + +TS
Sbjct: 12620 PGPPQPPFDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSC 12679
Query: 991 TITELVIGNEYYFRVFSENMCGLSEDATMTK 1021
+ +L+ G EY FRV +EN G+SE T K
Sbjct: 12680 RVGKLIPGQEYIFRVRAENRFGISEPLTSPK 12710
Score = 244 bits (623), Expect = 3e-64
Identities = 143/488 (29%), Positives = 242/488 (49%), Gaps = 34/488 (6%)
Query: 534 TVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSS----TLVIDIA 589
T+ V AG + +P G P P +WS+ D + RT +Y D++ +L I+ A
Sbjct: 19823 TLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDL-------RTRAYVDTTDSRTSLTIENA 19875
Query: 590 ERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGS 649
R+DSG Y + ++N A ++ VKV+D P PP TV +V + +++W+ P DGG+
Sbjct: 19876 NRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGA 19935
Query: 650 PILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPS 709
P+ Y IE+++ W+ + + C +++ + EG Y R+ N G+ P+
Sbjct: 19936 PVKNYHIEKREASKKAWVSVT-NNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETK 19994
Query: 710 RPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDE 769
SPP L V S++ +V++ W P+H G + + YV+E +G
Sbjct: 19995 EGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQ-------- 20046
Query: 770 NGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPIL 829
++W+ + T ++GL +++ F RV A N AG S+P+ P+L
Sbjct: 20047 ----------KNWVKC--AVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVL 20094
Query: 830 VKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKN-QINIR 888
+KE +EPP+I + T R G + + IP GKP P++T +DG + + N
Sbjct: 20095 IKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTE 20154
Query: 889 NSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWGEN 947
+ + I ++++ + +G+Y++ A I+I ++DRPGPP V I D+ E+
Sbjct: 20155 ITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDITEES 20214
Query: 948 VALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFS 1007
V L W PPK DG + +T Y + K + + W V RT + +L G EY FR+ +
Sbjct: 20215 VTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKA 20274
Query: 1008 ENMCGLSE 1015
EN G+S+
Sbjct: 20275 ENRFGISD 20282
Score = 244 bits (622), Expect = 4e-64
Identities = 157/500 (31%), Positives = 254/500 (50%), Gaps = 31/500 (6%)
Query: 522 PKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS 581
P + LD D V V AG +R+ +SG+PPP W+ ++ + + + E+ S
Sbjct: 10150 PDLQLDASVRDRIV-VHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEA---TIETTAIS 10205
Query: 582 STLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTE-VGDDWCIMNW 640
S++VI +R GVY + KNEAGE +I V V+D P P P + + ++ C + W
Sbjct: 10206 SSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTW 10265
Query: 641 EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAI 700
P DGGSPI Y IE+++ W + + + ++ + +I+G AY RI A N+I
Sbjct: 10266 FSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNA-TVQGLIQGKAYFFRIAAENSI 10324
Query: 701 GISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 757
G+ S V P+ V P L V VT TVT+ W PP + G + + YVLE
Sbjct: 10325 GMGPFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESR 10384
Query: 758 FEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAG 817
G+ + V N +L+ + K+T+ GL RV AVN G
Sbjct: 10385 LIGTEKFHK-----------------VTNDNLLSR-KYTVKGLKEGDTYEYRVSAVNIVG 10426
Query: 818 ASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDG 877
+P + ++PI K+ + PP + + K T RVGEA L + GKP+P+++W KD
Sbjct: 10427 QGKPSFCTKPITCKDELAPPTLHLDFRDKLTI--RVGEAFALTGRYSGKPKPKVSWFKDE 10484
Query: 878 AEI-DKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ 936
A++ + ++ +I+ + + KA+RS SGKY + V+ + ++DRPGPP
Sbjct: 10485 ADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPV 10544
Query: 937 -IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITEL 995
V ++V + + ++W PP DDG + IT Y I+K + W V +T+ +++L
Sbjct: 10545 GPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKL 10604
Query: 996 VIGNEYYFRVFSENMCGLSE 1015
+ G +Y FR+ +EN+ G+S+
Sbjct: 10605 LEGKDYIFRIHAENLYGISD 10624
Score = 239 bits (611), Expect = 8e-63
Identities = 151/488 (30%), Positives = 240/488 (49%), Gaps = 28/488 (5%)
Query: 530 DADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIA 589
D TVT+ AG LRL + +SG PPP WS+ + + TESY S L++D
Sbjct: 23079 DLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESY---SLLIVDKV 23135
Query: 590 ERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGS 649
R D+G Y I +N++G+ A++ VKV D P P + V EV D + WE P DGG+
Sbjct: 23136 NRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGA 23195
Query: 650 PILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPS 709
P+ Y +E K++ + R + C +T + ++EG Y R+ N GI +P S
Sbjct: 23196 PVNNYIVE-KREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETS 23254
Query: 710 RPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDE 769
+ V P L V VT +TVT+ W P + G + L GYVLE C G+
Sbjct: 23255 DAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGT-------- 23306
Query: 770 NGEAAYDLPAEDW--IVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQP 827
E W +V K + + T+T L + R++A N G SEP+
Sbjct: 23307 ----------ERWMKVVTLKPTV--LEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTA 23354
Query: 828 ILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI-DKNQIN 886
+ V+++ P I + ++T G V LVIP G+P P +W G+++ + ++
Sbjct: 23355 VTVQDLRVLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVT 23414
Query: 887 IRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWG 945
+ + IR+ +G+Y L++K + +I + I+D+PGPP +KI+++
Sbjct: 23415 VETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDA 23474
Query: 946 ENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRV 1005
++ ++W PP+ DG A ++GY +++ D W V E R++ T L GNEY FRV
Sbjct: 23475 TSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRV 23534
Query: 1006 FSENMCGL 1013
+ N G+
Sbjct: 23535 AATNRFGI 23542
Score = 239 bits (610), Expect = 1e-62
Identities = 152/526 (28%), Positives = 245/526 (46%), Gaps = 40/526 (7%)
Query: 508 YNVTLPAKVHVIDPPKIILDGLDADNT--------------VTVIAGNKLRLEIPISGEP 553
Y V+ K V DP +I L L AD+ + VI N + + +P +G P
Sbjct: 6992 YRVSAENKAGVSDPSEI-LGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYP 7050
Query: 554 PPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIK 613
P A W GDK ++E R++ ++ + LVI +ER D G+Y + L+N I
Sbjct: 7051 RPTATWCFGDK-VLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEID 7109
Query: 614 VKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDL 673
V V+ P P ++ D + WEPP DGGSP+ GY +E+++ W ++ D
Sbjct: 7110 VNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKV-MDF 7168
Query: 674 CKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPF---VPLAVTSPPTLLTVDSVT 730
+ F +++G Y ++ A N G +P+ P P V PP + T
Sbjct: 7169 VTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRT 7228
Query: 731 DTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLI 790
++ + W PP + G + + GY++E C GS + W+ + +
Sbjct: 7229 ANSIFLTWDPPKNDGGSRIKGYIVERCPRGS------------------DKWVACGEP-V 7269
Query: 791 DKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYI 850
+TK +TGL RVKA+N GAS+P ++ I + E P+I + L
Sbjct: 7270 AETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLT 7329
Query: 851 RRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKN-QINIRNSETDTIIFIRKAERSHSGKY 909
+ G + L GKP P++TW K + ++ +I I N + + I ++RS +G Y
Sbjct: 7330 VKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTY 7389
Query: 910 DLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQ 969
++ TA +++ ++D+PGPP I DV E+ LTW PP+DDG + IT Y ++
Sbjct: 7390 IIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVE 7449
Query: 970 KADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1015
+ S W + T+ T+L+ EY FRV +ENM G+ E
Sbjct: 7450 RRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGE 7495
Score = 239 bits (610), Expect = 1e-62
Identities = 138/399 (34%), Positives = 201/399 (50%), Gaps = 21/399 (5%)
Query: 620 PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTF 679
P PP P VT V D ++W P DGGSPILGY +ERK++ W ++ L F
Sbjct: 14887 PGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIF 14946
Query: 680 EPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWR 739
+ + +G+AYE R+ A N G SKPS PS P + L PP ++T TVT++W
Sbjct: 14947 KSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWA 15006
Query: 740 PPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITG 799
P++ G + Y++E DLP W+ AN I + +FT++G
Sbjct: 15007 KPEYTGGFKITSYIVE------------------KRDLPNGRWLKANFSNILENEFTVSG 15048
Query: 800 LPTDAKIFVRVKAVNAAGA-SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVN 858
L DA RV A NAAGA S P S I ++ +E PKI++ K T I + GEA
Sbjct: 15049 LTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVILKAGEAFR 15108
Query: 859 LVIPFQGKPRPELTWKKDGAEIDKN-QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDK 917
L G+P P + W KDG E++ ++ I+ ++ T + + + R SG Y L
Sbjct: 15109 LEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPG 15168
Query: 918 FVETASIDIQIIDRPGPPQ-IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSM 976
+++++DRPGPP+ + + +V E L+W PP DDG A I Y +QK + +
Sbjct: 15169 GFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRL 15228
Query: 977 EWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1015
W V T +T+L+ GNEY FRV + N G+ E
Sbjct: 15229 AWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGE 15267
Score = 239 bits (610), Expect = 1e-62
Identities = 162/609 (26%), Positives = 285/609 (46%), Gaps = 58/609 (9%)
Query: 429 DLKPLKILTPLTDQTVNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIH 486
D+KP + +V +G+++ ++ IS WTK+GLP++++ R+ V +
Sbjct: 16859 DVKPA-----FSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLT 16913
Query: 487 KLVIANALTEDEGDYVFAPDAYNVTLPAKVHVI-----DPPK--IILDGLDADNTVTVIA 539
L I +D G Y A + ++ DPPK + D + A++
Sbjct: 16914 TLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAES------ 16967
Query: 540 GNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRT-----ESYPDSSTLVIDIAERDDS 594
I +S PP + I++ T + +TL + +
Sbjct: 16968 -------ITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTE 17020
Query: 595 GVYHINLKNEAGEAHASIKVKVV-----DFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGS 649
+ I +N G++ A +V P PP P T + D ++ W P +GGS
Sbjct: 17021 YQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGS 17080
Query: 650 PILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPS 709
P++GY +ERK++ S W ++N + +T F+ + + EG+ YE R++A N +G+ K S S
Sbjct: 17081 PVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNS 17140
Query: 710 RPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDE 769
+V PP V +T++W P + G + + GY++E
Sbjct: 17141 ECYVARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVE-------------- 17186
Query: 770 NGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGA-SEPKYYSQPI 828
DLP W+ A+ + +T+FT++GL D + RV A NAAGA S+P + PI
Sbjct: 17187 ----KRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPI 17242
Query: 829 LVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKN-QINI 887
K+ +E P+I + + T + GE L GKP P + W + EI+++ + I
Sbjct: 17243 TAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEI 17302
Query: 888 RNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWGE 946
+N++ ++ ++ A R G+Y L+ ++ ++++++DRPGPP+ V++ V E
Sbjct: 17303 KNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSE 17362
Query: 947 NVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVF 1006
+LTW+PP DG + I+ Y ++K + + W V S +T+L+ GNEY FR+
Sbjct: 17363 KCSLTWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIM 17422
Query: 1007 SENMCGLSE 1015
+ N G+ E
Sbjct: 17423 AVNKYGVGE 17431
Score = 239 bits (610), Expect = 1e-62
Identities = 171/602 (28%), Positives = 283/602 (47%), Gaps = 51/602 (8%)
Query: 436 LTPLTDQTVNL--GKEICLKCEISENIP--GKWTKNGLPVQESDRLKVVHKGRIHKLVIA 491
L+ + +T+++ G+ + L I+ P W G ++ES+R+ V ++ KL I
Sbjct: 23368 LSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIR 23427
Query: 492 NALTEDEGDYVFAPDAYNVTLPA----KVHVIDPP-----KIILDGLDADNTVTVIAGNK 542
D G+Y + NVT KV ++D P I +D +DA + +
Sbjct: 23428 ETTIRDTGEYTL--ELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPE 23485
Query: 543 LRLEIPISG-----EPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVY 597
L P+SG + W +++ + + + + + R G Y
Sbjct: 23486 LDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSY 23545
Query: 598 HINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIE 657
L++E E +SI++ P PP + +V D + W PP DGGS + GY +E
Sbjct: 23546 ---LQSEVIECRSSIRI-----PGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVE 23597
Query: 658 RKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAV 717
RK+ ++ RW+R+N T + + EG+ YE R+ A+NA G KPS PS+P V +
Sbjct: 23598 RKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDP 23657
Query: 718 TSPPTLLTVDSVTDTT---VTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAA 774
+PP VTDTT V++ W P+ G + + GY++E ++ D++
Sbjct: 23658 IAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIE--------MQKVDQH---- 23705
Query: 775 YDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEII 834
+W N ++T+T LP A+ RV A NA G EP + V E++
Sbjct: 23706 ------EWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEML 23759
Query: 835 EPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDT 894
E P + ++ R G + L IP +GKP P W K+G +I K + I SET T
Sbjct: 23760 EYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAM-IATSETHT 23818
Query: 895 IIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWGENVALTWT 953
+ I++A+R SG YDL ++ + I +++I P P+ ++ +D+ +V ++W
Sbjct: 23819 ELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVSWR 23878
Query: 954 PPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL 1013
PP DDG A I GY +++ + W+T+ TS + L EY+FRV +EN G+
Sbjct: 23879 PPADDGGADILGYILERREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGI 23938
Query: 1014 SE 1015
S+
Sbjct: 23939 SK 23940
Score = 238 bits (607), Expect = 2e-62
Identities = 169/578 (29%), Positives = 277/578 (47%), Gaps = 44/578 (7%)
Query: 464 WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVH--VIDP 521
W K+G+ ++E R +++ L + + + D G YV T V+ V+D
Sbjct: 19451 WAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDK 19510
Query: 522 P-----KIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTE 576
P + ++GL A+ + I K S I EG ++
Sbjct: 19511 PGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQM--- 19567
Query: 577 SYPDSSTLVIDIAERDDSGVYHINLKNE--AGEAHASIKVKVVD---FPDPPVAPTVTEV 631
+S V + + ++ ++ + N+ GE S+ +K +D P PP + +T V
Sbjct: 19568 ----TSCKVTKLLKGNEY-IFRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSV 19622
Query: 632 GDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYE 691
+ + W P DGGS I GY IER++K S RW+R+N + + + EG YE
Sbjct: 19623 TKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYE 19682
Query: 692 VRIFAVNAIGISKPSMPS---RPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAG 748
R++A NA G+S PS S R P+ + SPP+ + TT+T+ W P G A
Sbjct: 19683 YRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAP 19742
Query: 749 LDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFV 808
+ GY +EY K+SD+ DW + + L T++TI+GL T A+
Sbjct: 19743 ITGYTVEY--------KKSDDT----------DWKTSIQSLRG-TEYTISGLTTGAEYVF 19783
Query: 809 RVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPR 868
RVK+VN GAS+P S P + KE E P I +++T I + G + + +PF+G+P
Sbjct: 19784 RVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPV 19843
Query: 869 PELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQI 928
P + W K ++ + + + +++ T + I A R+ SGKY L ++ + ++ +++
Sbjct: 19844 PNVLWSKPDTDL-RTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKV 19902
Query: 929 IDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRT 988
+D PGPP + ++DV E+ L+W P++DG A + Y I+K + W +V + +R
Sbjct: 19903 LDTPGPPTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCNRL 19962
Query: 989 SATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVI 1026
S +T L G YYFRV EN G+ A TKE I
Sbjct: 19963 SYKVTNLQEGAIYYFRVSGENEFGVGIPAE-TKEGVKI 19999
Score = 236 bits (603), Expect = 7e-62
Identities = 153/533 (28%), Positives = 261/533 (48%), Gaps = 43/533 (8%)
Query: 518 VIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTES 577
++ PP+ LD D T+ + AG +RL +P+ G PPPK WS+ + + + G + +S
Sbjct: 13315 ILIPPEGELDA-DLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIG-LDIKS 13372
Query: 578 YPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCI 637
+ L + + D+G Y + L+N G+ +I VKV+D P PPV TV E+ D
Sbjct: 13373 TDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAY 13432
Query: 638 MNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAV 697
+ WEPP DGGSPI+ Y ++++ + W + + C +T+F + EG +Y R+FA
Sbjct: 13433 VTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTE-CSKTSFRVANLEEGKSYFFRVFAE 13491
Query: 698 NAIGISKPSMPSRPFVPLAVTSPPTL-LTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEY 756
N GI P +R V + T P + L V SV+ ++ ++ W+ P G + + GYV+++
Sbjct: 13492 NEYGIGDPG-ETRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDF 13550
Query: 757 CFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAA 816
++EN W K L +++ L + RV A N
Sbjct: 13551 L---------TEEN----------KWQRVMKSL--SLQYSAKDLTEGKEYTFRVSAENEN 13589
Query: 817 GASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKK- 875
G P + ++ ++ + P + + Y+ + L IP +GKP P ++WKK
Sbjct: 13590 GEGTPSEIT--VVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKG 13647
Query: 876 DGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPG-P 934
+ ++++ +S +T + + ++S +GKY + +K + +I I+++ +PG P
Sbjct: 13648 EDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKPGIP 13707
Query: 935 PQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITE 994
+K ++V E + L W PPKDDG + IT Y ++K D + +W T +T+ +T
Sbjct: 13708 TGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAVQKTTFRVTR 13767
Query: 995 LVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAP 1047
L G EY FRV +EN G+ E K ++AR FD +AP
Sbjct: 13768 LHEGMEYTFRVSAENKYGVGEG---LKSEPIVAR----------HPFDVPDAP 13807
Score = 236 bits (603), Expect = 7e-62
Identities = 185/698 (26%), Positives = 312/698 (44%), Gaps = 80/698 (11%)
Query: 364 EVSEDDANVKWFK----NGEEII-------PGPKSRYRIRVEGKKHILIIEGATKADAAE 412
+VS+ A++ W K G ++ P ++ I E K ++ G + +
Sbjct: 17851 DVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQ 17910
Query: 413 YSVMTTG--GQSSAKL--------SVDLKPLKILTPLTDQTVNLGKEICLKCEI----SE 458
+ V G+S ++ + ++P + P ++ G+++ ++ +
Sbjct: 17911 FRVKAYNEKGKSDPRVLGVPVIAKDLTIQP-SLKLPFNTYSIQAGEDLKIEIPVIGRPRP 17969
Query: 459 NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAP--DAYNVTLPAKV 516
NI W K+G P++++ R+ V L I +D G Y A T V
Sbjct: 17970 NI--SWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSV 18027
Query: 517 HVIDPP-----KIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSG 571
V++ P + D + AD V IS EPP + I+E
Sbjct: 18028 IVLEKPGPPVGPVRFDEVSADFVV-------------ISWEPPAYTGGCQISNYIVEKRD 18074
Query: 572 RIRTESYPDSSTLV---IDIAERDDSGVYHINL--KNEAGE-AHASIKVKVVDFP----D 621
T + S+T+ I I + Y + +N G+ A K +V +P
Sbjct: 18075 TTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEPG 18134
Query: 622 PPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEP 681
PP P VT + D ++ W P DGG+ I+GY +E+K+K S W++LN ++T F+
Sbjct: 18135 PPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKT 18194
Query: 682 KKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPP 741
+ EG+ YE ++ A N +GI KPS S FV PP +T VT++W+ P
Sbjct: 18195 TGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIVITRNNVTLKWKKP 18254
Query: 742 DHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLP 801
+ G + + GY++E DLP W+ A+ + +T+FT++GL
Sbjct: 18255 AYDGGSKITGYIVE------------------KKDLPDGRWMKASFTNVLETEFTVSGLV 18296
Query: 802 TDAKIFVRVKAVNAAG-ASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLV 860
D + RV A NAAG SEP S I ++ I+ P + K + GE L
Sbjct: 18297 EDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGETFVLE 18356
Query: 861 IPFQGKPRPELTWKKDGAEIDKN--QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKF 918
+GKP P++ W KDG E+++ ++ I+++ T + ++ R+ G+Y L++
Sbjct: 18357 ADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGG 18416
Query: 919 VETASIDIQIIDRPGPPQ-IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSME 977
++ I ++++DRPGPP+ +K+ V E L W PP DG A I+ Y I+K + +
Sbjct: 18417 TKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLS 18476
Query: 978 WFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1015
W V + +T+L+ GNEY FRV + N G+ E
Sbjct: 18477 WTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGE 18514
Score = 234 bits (596), Expect = 5e-61
Identities = 171/604 (28%), Positives = 285/604 (47%), Gaps = 46/604 (7%)
Query: 428 VDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVVHKGRIHK 487
+DLK +LT T+ L E ++ + + K+ + S R+K+ + K
Sbjct: 11831 LDLKLSGVLTVKAGDTIRL--EAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSK 11888
Query: 488 LVIANALTEDEGDYVFAPD--AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRL 545
+ A D G YV A + A V+V+D P G + + ++ ++
Sbjct: 11889 FSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKP-----GPVRNLKIVDVSSDRCT- 11942
Query: 546 EIPISGEPPPKAMWSRGDKAIMEG--SGRIRTESYPDS----STLVIDIAERDDSGVYHI 599
+ +PP I+E + R+ +Y + T V + E ++ ++ +
Sbjct: 11943 ---VCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEY-IFRV 11998
Query: 600 NLKNEAG-----EAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGY 654
+N+ G E+ I D P P P VT+V + + W PP YDGG I GY
Sbjct: 11999 RAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGY 12058
Query: 655 FIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV- 713
F+E+K+K S+RW+ +N E + + ++ Y+ R+ A N IGI +PS+PSRP V
Sbjct: 12059 FLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVA 12118
Query: 714 --PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENG 771
P+ PPT V T ++T+ W P + G A + GYV+E K +D +
Sbjct: 12119 KDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEM------RPKIADAS- 12171
Query: 772 EAAYDLPAEDWIVANKDL-IDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILV 830
P E W N + + +FT+T L + + RV A N G P + I
Sbjct: 12172 ------PDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKP 12225
Query: 831 KEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAE--IDKNQINIR 888
KEI+EPP+I + +++ I R G + L +G+P P++TW+K G + + K Q+++
Sbjct: 12226 KEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDL- 12284
Query: 889 NSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENV 948
+T + I + R SGKY L + + ++++++D PGP +K+ DV +
Sbjct: 12285 -VDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSC 12343
Query: 949 ALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSE 1008
++W PP++DG + +T Y ++K + W TV +TS +T LV GNEYYFRV +
Sbjct: 12344 HVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAV 12403
Query: 1009 NMCG 1012
N G
Sbjct: 12404 NEYG 12407
Score = 233 bits (594), Expect = 8e-61
Identities = 202/725 (27%), Positives = 321/725 (44%), Gaps = 83/725 (11%)
Query: 332 STELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKW----FKNGEEIIP---- 383
S L +REP I V ++ ED +E++ EV+++ + W + G EII
Sbjct: 10333 SEALVIREP-ITVPERPED--------LEVK-EVTKNTVTLTWNPPKYDGGSEIINYVLE 10382
Query: 384 ----GPKSRYRIRVEGK-KHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTP 438
G + +++ + ++G + D EY V K S KP+
Sbjct: 10383 SRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDE 10442
Query: 439 LTDQTVNLGKEICLKCEISE------NIPGK------WTKNGLPVQESDRLKVVHKGRIH 486
L T++L L + E GK W K+ V E DR +
Sbjct: 10443 LAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATL 10502
Query: 487 KLVIANALTEDEGDYVFAPDAYNVTLPAK----VHVIDPPKIILDGLDADNTVTVIAGNK 542
L A D G Y + N T K V+V+D P + + D
Sbjct: 10503 ALEKIKAKRSDSGKYCVVVE--NSTGSRKGFCQVNVVDRPGPPVGPVSFDEVT------- 10553
Query: 543 LRLEIPISGEPPPKAMWSRGDKAIMEGSGRIR------TESYPDSSTLVIDIAERDDSGV 596
+ + IS +PP S+ I+E + T + ++ V + E D +
Sbjct: 10554 -KDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDY-I 10611
Query: 597 YHINLKNEAG--EAHASIKVKVVD---FPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPI 651
+ I+ +N G + S +K D PD P P VTEV D ++ W P +DGG PI
Sbjct: 10612 FRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKP-HDGGKPI 10670
Query: 652 LGYFIERKKKQSSRWMRLNFD-LCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSR 710
Y +E+++ S RW R+ D + T F ++EG YE R+ A N IGI PS PS+
Sbjct: 10671 TNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSK 10730
Query: 711 PFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQS 767
P P+A SPP T +V + W+PP H G + + GY++EY K
Sbjct: 10731 PVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEY-------QKVG 10783
Query: 768 DENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQP 827
DE A P + +TK+ +TGL RV AVNAAG S+P + +P
Sbjct: 10784 DEEWRRANHTP---------ESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEP 10834
Query: 828 ILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINI 887
+LVK+ +EPP++ + ++ + +VG+ + L +G P P++TWKK+ + + I
Sbjct: 10835 VLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAP-TKARI 10893
Query: 888 RNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGEN 947
+ + + IR A G Y L V+ +T S+ + ++D+PGPP+ +++ ++ ++
Sbjct: 10894 DVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDS 10953
Query: 948 VALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFS 1007
LTW P DDG + IT Y +++ D S +W + + S L GN+Y FRV +
Sbjct: 10954 CYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAA 11013
Query: 1008 ENMCG 1012
EN G
Sbjct: 11014 ENQYG 11018
Score = 233 bits (593), Expect = 1e-60
Identities = 172/611 (28%), Positives = 288/611 (47%), Gaps = 45/611 (7%)
Query: 241 LKRMRREEKKSAAFA-------KILDPAYQVDKGGR--VRFVVELADPKLEVKWYKNGQE 291
L R E KSAA +I++P ++ + V F ++ + +KW KNG+E
Sbjct: 6341 LTNHRGENVKSAANLIVEEEDLRIVEPLKDIETMEKKSVTFWCKVNRLNVTLKWTKNGEE 6400
Query: 292 IRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDT 351
+ + + + +L I +C D+ EY VTAG +K EL + E P + LED
Sbjct: 6401 VPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYIVTAGQDKSVAELLIIEAPTEFVEHLEDQ 6460
Query: 352 TAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAA 411
T + C++S + ANVKW++NG EI G K Y+ +G H LII+ D
Sbjct: 6461 TVTEFDDAVFSCQLSREKANVKWYRNGREIKEGKK--YKFEKDGSIHRLIIKDCRLDDEC 6518
Query: 412 EYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLP 470
EY+ +S A+L V+ P++I+ P D G ++ E++ + + +W +N +
Sbjct: 6519 EYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQWLRNNMV 6578
Query: 471 VQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLD 530
V + D+ +++ +G+IH+L I + D+G+Y F A + AK+ + PKI
Sbjct: 6579 VVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFI--AKDKEARAKLELAAAPKI----KT 6632
Query: 531 ADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAE 590
AD + V G L + +P P +A W + ++ + + ++ + ++ I A+
Sbjct: 6633 ADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKT----IDTTAEQTSFRILEAK 6688
Query: 591 RDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSP 650
+ D G Y I L+N+ G+A I +KV+D P P VTE D + WE P DGGS
Sbjct: 6689 KGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSK 6748
Query: 651 ILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIE-GVAYEVRIFAVNAIGISKPSMPS 709
I+GY +ER+ + W+ L D + F + + GV Y R+ A N +G +P
Sbjct: 6749 IIGYVVERRDIKRKTWV-LATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETD 6807
Query: 710 RPFVPLA---VTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQ 766
P + V PP +T+ V V++ W PP++ G A + YV+E TS +
Sbjct: 6808 NPVEARSKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIE--LRDKTSIR- 6864
Query: 767 SDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQ 826
+ A + AED D+++ +++ RV+A N G +P +
Sbjct: 6865 ----WDTAMTVRAEDLSATVTDVVEGQEYSF-----------RVRAQNRIGVGKPSAATP 6909
Query: 827 PILVKEIIEPP 837
+ V + IE P
Sbjct: 6910 FVKVADPIERP 6920
Score = 232 bits (592), Expect = 1e-60
Identities = 158/525 (30%), Positives = 252/525 (48%), Gaps = 40/525 (7%)
Query: 520 DPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWS---RGDKAIMEGSGRI--- 573
+ P++ +D + A + + AG+++R+ I G P PK+ W + KA+ +G I
Sbjct: 9434 EEPEVFID-IGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPED 9492
Query: 574 -RTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVG 632
+ E+ +SS ++I +R +G Y I KN+AG+ A+ +VKV+D P PP V+++
Sbjct: 9493 AQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDIT 9552
Query: 633 DDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEV 692
C ++W+ P DGG I GY IE++ W ++N D C TTF ++ Y
Sbjct: 9553 RGSCRLSWKMPDDDGGDRIKGYVIEKRTIDGKAWTKVNPD-CGSTTFVVPDLLSEQQYFF 9611
Query: 693 RIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGL 749
R+ A N GI P + P+ PP L + +T TV + W+PP + G + +
Sbjct: 9612 RVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPV 9671
Query: 750 DGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVR 809
Y++E T K+ E W NK +++ +FT+ L + R
Sbjct: 9672 THYIVECLAWDPTGTKK-------------EAWRQCNKRDVEELQFTVEDLVEGGEYEFR 9718
Query: 810 VKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRP 869
VKAVNAAG S+P P + PP I LK+ G VN+V +G P P
Sbjct: 9719 VKAVNAAGVSKPSATVGPCDCQRPDMPPSI----DLKEFMEVEEGTNVNIVAKIKGVPFP 9774
Query: 870 ELTW------KKDGAE---IDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVE 920
LTW K D E D + + +T T++ I ++ RS +G Y + +
Sbjct: 9775 TLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLV-IPQSRRSDTGLYTITAVNNLGTA 9833
Query: 921 TASIDIQIIDRPGPP-QIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF 979
+ + + ++ RPGPP +K E V + + L+W PPKDDG + IT Y I+K + W
Sbjct: 9834 SKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWV 9893
Query: 980 TVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESA 1024
V + TI +L+ G+EY FR+ ++N G+ E E+A
Sbjct: 9894 HVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETA 9938
Score = 232 bits (591), Expect = 2e-60
Identities = 174/651 (26%), Positives = 304/651 (46%), Gaps = 60/651 (9%)
Query: 386 KSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVN 445
K++Y+ R + + I + +D +++ LSV +K L TV
Sbjct: 12887 KAQYQFRAIARTAVNISPPSEPSDPV--TILAENVPPRIDLSVAMKSLL--------TVK 12936
Query: 446 LGKEICLKCEI-SENIPG-KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF 503
G +CL + + +P W K+G ++ ++ +K+ + + L + + +D GDY
Sbjct: 12937 AGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTI 12996
Query: 504 APDAYNVTLPA--KVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSR 561
+ + + A K+ V+D P G A + + ++ L S EPP + S
Sbjct: 12997 TAENSSGSKSATIKLKVLDKP-----GPPASVKINKMYSDRAML----SWEPPLEDGGSE 13047
Query: 562 GDKAIMEGSGRIRTESYPDSSTLVI---DIAERDDSGVYHINL--KNEAGEA-----HAS 611
I++ R S+T+ I + + + Y + +N+ G +
Sbjct: 13048 ITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPA 13107
Query: 612 IKVKVVDFP---DPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMR 668
I D P DPPV +T+ D ++W+PPA DGGSPI GY +E+++ Q+ W +
Sbjct: 13108 IAKNPYDPPGRCDPPVISNITK---DHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTK 13164
Query: 669 LNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLT 725
+N E T + + EG YE R+ A+N G KPS S+ P PP
Sbjct: 13165 VNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPK 13224
Query: 726 VDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVA 785
V T ++V++ W P + G + + GY++E K++D + +LP
Sbjct: 13225 VYDTTRSSVSLSWGKPAYDGGSPIIGYLVE--------VKRADSDNWVRCNLPQN----- 13271
Query: 786 NKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHL 845
+ KT+F +TGL D + RV AVN G S+P K+I+ PP+ + L
Sbjct: 13272 ----LQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADL 13327
Query: 846 KQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI-DKNQINIRNSETDTIIFIRKAERS 904
++T I R G + L +P +G+P P++TW K + D+ ++I++++ DT + +
Sbjct: 13328 RKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKY 13387
Query: 905 HSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAIT 964
+GKY L ++ + +I ++++D PGPP V ++++ ++ +TW PP DG + I
Sbjct: 13388 DAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPII 13447
Query: 965 GYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1015
Y +QK D + W TV +TS + L G Y+FRVF+EN G+ +
Sbjct: 13448 NYVVQKRDAERKSWSTVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGD 13498
Score = 229 bits (585), Expect = 9e-60
Identities = 149/513 (29%), Positives = 245/513 (47%), Gaps = 28/513 (5%)
Query: 506 DAYNVTLPAK-VHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDK 564
D+ VT K V + P++ +D + T V AG +RL I G P P A+WS+ D
Sbjct: 21966 DSCEVTGTIKAVDRLTAPELDIDA-NFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDS 22024
Query: 565 AIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPV 624
+ + T+S+ STL ++ R+D+G Y + ++N +G + VKV+D P PP
Sbjct: 22025 NLSLRADIHTTDSF---STLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGPPG 22081
Query: 625 APTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKM 684
T +V + W+ P DGG+ I Y +E+++ W ++ + C F+ +
Sbjct: 22082 PITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVIS-EKCTRQIFKVNDL 22140
Query: 685 IEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHI 744
EGV Y R+ AVN G+ +P P V +PP L V + ++ + W PDH
Sbjct: 22141 AEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHD 22200
Query: 745 GAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDA 804
G + + GY+LE +GS + W+ A + FT+ L
Sbjct: 22201 GGSRITGYLLEMRQKGS------------------DFWVEAGH--TKQLTFTVERLVEKT 22240
Query: 805 KIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQ 864
+ RVKA N AG SEP+ +++KE P + Q + G + +P
Sbjct: 22241 EYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPIS 22300
Query: 865 GKPRPELTWKKDGAEI-DKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETAS 923
G+P P++TWK + + + ++++I ++ T + ++ + R SG+Y L ++ V+T S
Sbjct: 22301 GRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFS 22360
Query: 924 IDIQIIDRPGP-PQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVI 982
+ + +I RPGP +++ V E+ L+W PKD G IT Y ++K + + W V
Sbjct: 22361 VTVVVIGRPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVN 22420
Query: 983 EHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1015
RT +T L EY FRV SEN G+S+
Sbjct: 22421 SSVKRTQIKVTHLTKYMEYSFRVSSENRFGVSK 22453
Score = 229 bits (584), Expect = 1e-59
Identities = 159/586 (27%), Positives = 270/586 (46%), Gaps = 42/586 (7%)
Query: 465 TKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKI 524
+++G+P++ + R + + ++T D G Y + T A ++++
Sbjct: 20139 SRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIV----- 20193
Query: 525 ILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIM---EGSGRIRTESYPDS 581
+LD T V+ + + + EPP S+ I+ E S + TE
Sbjct: 20194 VLDR-PGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATV 20252
Query: 582 STLVIDIAERDDSGVYHINLKNE--------AGEAHASIKVKVVDFPDPPVAPTVTEVGD 633
+ ++ + + Y +K E A ++K+ P PP P VT V
Sbjct: 20253 ARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTT-PGPPSTPWVTNVTR 20311
Query: 634 DWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVR 693
+ + W P +GGS ++GY +E K + S W + N + + T F+ + G+ YE R
Sbjct: 20312 ESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFR 20371
Query: 694 IFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYV 753
++A NA G+ KPS PS P + + PP + + ++ +V++ W+ P G + + GY+
Sbjct: 20372 VYAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYI 20431
Query: 754 LEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAV 813
+E DLP W A+ + +T+F I+GL +++ RV A
Sbjct: 20432 VE------------------RRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFAR 20473
Query: 814 NAAGA-SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELT 872
NA G+ S P PI + P I +P + R G +V L GKP P +
Sbjct: 20474 NAVGSISNPSEVVGPITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIE 20533
Query: 873 WKKDGAEIDKNQINIRNSETD-TIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDR 931
W KD E+ N + + TD I I+ A+R +SG Y+L+++ +A+I +QI+D+
Sbjct: 20534 WYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDK 20593
Query: 932 PGPP-QIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSA 990
PGPP ++ + V E + L W PP DDG A IT Y ++K + + W V EH
Sbjct: 20594 PGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVSEHLEECII 20653
Query: 991 TITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNP 1036
T T+++ GNEY FRV + N G+ E + +V+A++ + P
Sbjct: 20654 TTTKIIKGNEYIFRVRAVNKYGIGEP---LESDSVVAKNAFVTPGP 20696
Score = 228 bits (581), Expect = 3e-59
Identities = 172/638 (26%), Positives = 274/638 (42%), Gaps = 44/638 (6%)
Query: 394 EGKKHILIIEGATKADAAEYSVMTTGGQSSAKL-SVDLKPLKILTPLTDQTVNLGKEICL 452
EGK++ + + S +T + +DLK L L L + N +I +
Sbjct: 13575 EGKEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPI 13634
Query: 453 KCEISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTL 512
K + + ++ W K P+ R+ V L++ + D G Y T
Sbjct: 13635 KGKPAPSV--SWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTK 13692
Query: 513 PA--KVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGS 570
+ V+ P I + D VT A + + PP S I+E
Sbjct: 13693 EGTISIKVVGKPGIPTGPIKFDE-VTAEA-------MTLKWAPPKDDGGSEITNYILEKR 13744
Query: 571 GRIRTE-----SYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVV-----DFP 620
+ + S +T + + ++ +N+ G +V D P
Sbjct: 13745 DSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVP 13804
Query: 621 DPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFE 680
D P P + +V D + W P GGSPI GY +E K++ S W R N + F+
Sbjct: 13805 DAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFK 13864
Query: 681 PKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRP 740
+ EG+ YE R+ A+N G+ KPS+PS P V L PP V ++T +VT+ W
Sbjct: 13865 VTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTE 13924
Query: 741 PDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGL 800
P + G L GY++E DLP++ W+ AN + + FT+T L
Sbjct: 13925 PKYDGGHKLTGYIVE------------------KRDLPSKSWMKANHVNVPECAFTVTDL 13966
Query: 801 PTDAKIFVRVKAVNAAGA-SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNL 859
K R++A N AGA S P ++ I+ K+ E P I + +K + G+ + L
Sbjct: 13967 VEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVL 14026
Query: 860 -VIPFQGKPRPELTWKKDGAEIDKNQI-NIRNSETDTIIFIRKAERSHSGKYDLQVKVDK 917
I GKP P+ +W K G +I + I I ++ T +++ I+ A R +G+Y +
Sbjct: 14027 NAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPF 14086
Query: 918 FVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSME 977
+ + + ++D PGPP V+I +V E LTWTPP +DG + I Y ++K + +
Sbjct: 14087 GTKVEHVKVTVLDVPGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLL 14146
Query: 978 WFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1015
W V E T+L+ GNEY FRV + N G E
Sbjct: 14147 WTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYGKGE 14184
Score = 227 bits (579), Expect = 4e-59
Identities = 156/571 (27%), Positives = 260/571 (45%), Gaps = 50/571 (8%)
Query: 464 WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF--APDAYNVTLPAKVHVIDP 521
W K+G ++E+ R+ V + L I A ED G Y + A ++T+P + V+D
Sbjct: 19056 WRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDR 19115
Query: 522 P----KIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTES 577
P I +D + D+ I IS PP + I+E T
Sbjct: 19116 PGPPGPIRIDEVSCDS-------------ITISWNPPEYDGGCQISNYIVEKKETTSTTW 19162
Query: 578 YPDSSTLV---IDIAERDDSGVYHINL-------KNEAGEAHASIKVKVVDFPDPPVAPT 627
+ S + I I Y + K+ E+ A + P PP P
Sbjct: 19163 HIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPK 19222
Query: 628 VTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEG 687
V ++ W+ P DGGS ++GY +E K++ S W + N L +T + + EG
Sbjct: 19223 VVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIADTQMKVSGLDEG 19282
Query: 688 VAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAA 747
+ YE R++A N GI K S P PP V ++T +V+++W P + G A
Sbjct: 19283 LMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGA 19342
Query: 748 GLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIF 807
+ GY++E +LP W+ N I +T F +T L D +
Sbjct: 19343 KITGYIVE------------------RRELPDGRWLKCNYTNIQETYFEVTELTEDQRYE 19384
Query: 808 VRVKAVNAA-GASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGK 866
RV A NAA SEP + PI+VK+ +EPP++ + + + + GE + + G+
Sbjct: 19385 FRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGR 19444
Query: 867 PRPELTWKKDGAEIDKN-QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASID 925
P P ++W KDG EI++ + I +++ T++ ++ R +G+Y L +K + +++
Sbjct: 19445 PLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVN 19504
Query: 926 IQIIDRPGPPQ-IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEH 984
+++D+PGPP ++I + E +L+W P++DG A I Y ++K + + W
Sbjct: 19505 CKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGE 19564
Query: 985 YHRTSATITELVIGNEYYFRVFSENMCGLSE 1015
TS +T+L+ GNEY FRV N G+ E
Sbjct: 19565 LQMTSCKVTKLLKGNEYIFRVTGVNKYGVGE 19595
Score = 226 bits (575), Expect = 1e-58
Identities = 154/509 (30%), Positives = 238/509 (46%), Gaps = 33/509 (6%)
Query: 519 IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESY 578
++PP++ILD A + G+ LRL I G P PK W + D+ + + R +
Sbjct: 10841 LEPPELILDANMAREQ-HIKVGDTLRLSAIIKGVPFPKVTWKKEDR---DAPTKARIDVT 10896
Query: 579 PDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIM 638
P S L I A +D G+Y + ++N AG S+KV V+D P PP V+E+ D C +
Sbjct: 10897 PVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYL 10956
Query: 639 NWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVN 698
W+ P DGGS I Y +ER+ S++W L+ K++ F K + EG Y R+ A N
Sbjct: 10957 TWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHF-AKHLNEGNQYLFRVAAEN 11015
Query: 699 AIG---ISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLE 755
G + P + PL PP L V T V++ W PD G + + GY++E
Sbjct: 11016 QYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVE 11075
Query: 756 YCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNA 815
Y EG+ +DWI + + +TGL RVKA N
Sbjct: 11076 YQEEGT------------------QDWI--KFKTVTNLECVVTGLQQGKTYRFRVKAENI 11115
Query: 816 AGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKK 875
G P + PI +E + PP + + L + + + G V +G P P W
Sbjct: 11116 VGLGLPD-TTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTT 11174
Query: 876 DGAEIDKNQ-INIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGP 934
DG+EI ++ + +++ I+ R +G+Y + V +T ++ + ++D PGP
Sbjct: 11175 DGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGP 11234
Query: 935 PQ-IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATIT 993
P + I DV E++ ++W PPKDDG + + Y ++K D + W V +T I
Sbjct: 11235 PTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIP 11294
Query: 994 ELVIGNEYYFRVFSENMCGLSE--DATMT 1020
L G EY FRV +EN G+ D+T T
Sbjct: 11295 HLQKGCEYVFRVRAENKIGVGPPLDSTPT 11323
Score = 224 bits (572), Expect = 3e-58
Identities = 142/494 (28%), Positives = 240/494 (48%), Gaps = 29/494 (5%)
Query: 529 LDAD--NTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVI 586
LDA+ T+ V AG +R+ +PI G P P+ W++ + + + TES+ + L+I
Sbjct: 14406 LDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESF---TLLII 14462
Query: 587 DIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYD 646
R D+G + + ++N AG+ + V+V+D P P + T++ D ++W+ P D
Sbjct: 14463 PECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLID 14522
Query: 647 GGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPS 706
GGS I Y +E+++ + C + T++ + EG Y R+ A N GI +P+
Sbjct: 14523 GGSRITNYIVEKREATRKSYSTATTK-CHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPT 14581
Query: 707 MPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQ 766
+ P SPP L + +T +TV++ W P H G + + GYV+E +GS
Sbjct: 14582 ETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGS----- 14636
Query: 767 SDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQ 826
+ W + + + + L + +V AVN+AG S P+ S+
Sbjct: 14637 -------------DQW--THITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPR-ESR 14680
Query: 827 PILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ-I 885
P++VKE P++ + ++ I + G+ + + IP G+P+P +TWKK + + Q +
Sbjct: 14681 PVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRV 14740
Query: 886 NIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVW 944
N + T TI+ I + RS SG Y L + I IQ+ D PGPP +K ++V
Sbjct: 14741 NFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVS 14800
Query: 945 GENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFR 1004
+ V +W PP++DG I+ Y ++ S W + RT+ T L G EY FR
Sbjct: 14801 SDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIRTTYKATRLTTGLEYQFR 14860
Query: 1005 VFSENMCGLSEDAT 1018
V ++N G+ T
Sbjct: 14861 VKAQNRYGVGPGIT 14874
Score = 224 bits (570), Expect = 5e-58
Identities = 165/572 (28%), Positives = 264/572 (46%), Gaps = 51/572 (8%)
Query: 464 WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV--FAPDAYNVTLPAKVHVIDP 521
W K+ +P++++ R+ L I +A ED G YV A V V+D
Sbjct: 15809 WHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDK 15868
Query: 522 P-----KIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTE 576
P + +D + AD+ I +S PP S + I+E T
Sbjct: 15869 PGPPTGPVKMDEVTADS-------------ITLSWGPPKYDGGSSINNYIVEKRDTSTTT 15915
Query: 577 SYPDSSTLVIDI--AERDDSGV---YHINLKNEAGEA-HASIKVKVVDF----PDPPVAP 626
S+T+ A R +G + I +N G++ + + + V + P PP P
Sbjct: 15916 WQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTP 15975
Query: 627 TVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIE 686
VT D + W P DGGS ++GY +ERK++ S W++LN +T F+ + E
Sbjct: 15976 VVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEE 16035
Query: 687 GVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGA 746
GV YE R+ A N +GI KPS S +V PP VT +VT++W+ P + G
Sbjct: 16036 GVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGG 16095
Query: 747 AGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKI 806
+ + GY++E +LP W+ A+ I T F +TGL D +
Sbjct: 16096 SKITGYIVE------------------KKELPEGRWMKASFTNIIDTHFEVTGLVEDHRY 16137
Query: 807 FVRVKAVNAAGA-SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQG 865
RV A NAAG SEP + I ++ ++PP+I + K T + GE+ + G
Sbjct: 16138 EFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYG 16197
Query: 866 KPRPELTWKKDGAEIDKN-QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASI 924
KP P + W K E+ ++ I++++ T + ++ A R SG Y L+ K + ++
Sbjct: 16198 KPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTV 16257
Query: 925 DIQIIDRPGPPQ-IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIE 983
+++++DRPGPP+ V I V E L W PP DG + I Y +++ + + W V
Sbjct: 16258 NVKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDA 16317
Query: 984 HYHRTSATITELVIGNEYYFRVFSENMCGLSE 1015
+ S +T+L+ GNEY FR+ + N G+ E
Sbjct: 16318 NVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGE 16349
Score = 220 bits (560), Expect = 7e-57
Identities = 161/544 (29%), Positives = 248/544 (45%), Gaps = 66/544 (12%)
Query: 520 DPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYP 579
+ P+I LD + +TV AG K+ L ++G+P PK W++ D I++ RI E+ P
Sbjct: 7314 EAPEIFLD-VKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADM-ILKQDKRITIENVP 7371
Query: 580 DSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMN 639
ST+ I ++R D+G Y I N G A A ++V V+D P PP A +T+V ++ C++
Sbjct: 7372 KKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLT 7431
Query: 640 WEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNA 699
W PP DGGS I Y +ER+ S W +L+ K+T F+ K+I Y R+ A N
Sbjct: 7432 WNPPRDDGGSKITNYVVERRATDSEVWHKLS-STVKDTNFKATKLIPNKEYIFRVAAENM 7490
Query: 700 IGISKP--SMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 757
G+ +P + P PPT L +T VT+ W PD G + + GY +E
Sbjct: 7491 YGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVE-- 7548
Query: 758 FEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAG 817
D + W+ NK + T + + GL K RV A N AG
Sbjct: 7549 ----------------RLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAG 7592
Query: 818 ASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKK-- 875
+P ++PIL+K+ I+PP +K GK L W K
Sbjct: 7593 PGKPSKSTEPILIKDPIDPPWPPGKPTVKDV----------------GKTSVRLNWTKPE 7636
Query: 876 --DGAEIDKNQINIRNSETDTIIFIRKAE-----------RSHSGKYDLQVK-VDKFVET 921
GA+I+ I + + TD ++R AE +Y +V+ V+K E+
Sbjct: 7637 HDGGAKIESYVIEMLKTGTDE--WVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGES 7694
Query: 922 ASID-------IQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKK 974
+ + + P PP+ +++ ++ L WT P+ DG + IT Y ++K D +
Sbjct: 7695 EPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVR 7754
Query: 975 SMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYK 1034
W TV T T+T L G+ Y FRV +EN G S+ + E +V+A+D
Sbjct: 7755 RKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEI--EDSVLAKDTFTTP 7812
Query: 1035 NPVY 1038
P Y
Sbjct: 7813 GPPY 7816
Score = 219 bits (559), Expect = 9e-57
Identities = 174/636 (27%), Positives = 290/636 (45%), Gaps = 67/636 (10%)
Query: 428 VDLKPLKILTPLTDQTV-NLGKEICLKCEISENIPG--KWTKNGLPVQESDRLKVVHKGR 484
V+ +K+ D + G+ L+ ++S P +W+K+G ++ + +L++
Sbjct: 15084 VEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADF 15143
Query: 485 IHKLVIANALTEDEGDYV--------FAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVT 536
LV ++ D G Y FA +NV V+D P + VT
Sbjct: 15144 STNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVK------VLDRP----GPPEGPLAVT 15193
Query: 537 VIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIR-----TESYPDSSTLVIDIAER 591
+ K L S PP ++ D I++ R S + L + +
Sbjct: 15194 EVTSEKCVL----SWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLK 15249
Query: 592 DDSGVYHINLKNEAG-----EAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYD 646
+ ++ + N+ G E+ + V PDPP P VT + D ++ W P D
Sbjct: 15250 GNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSD 15309
Query: 647 GGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPS 706
GGS I+ Y +ER+ K RW++ N + ++ + EG YE RI A NA GIS PS
Sbjct: 15310 GGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPS 15369
Query: 707 MPSRPFVPLAVT----SPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGST 762
P+ PF T PP V + +++++ W P + G + + GY++E
Sbjct: 15370 -PTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIA----- 15423
Query: 763 SAKQSDENGEAAYDLPAED-W-IVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASE 820
LP ED W IV + T +TITGL + + +R+ A+N+ G E
Sbjct: 15424 --------------LPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGE 15469
Query: 821 PKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKD-GAE 879
P ++ + PP+I + L++ R + L +P +G+P PE+ W +D G
Sbjct: 15470 PALVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGES 15529
Query: 880 IDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVK 939
+DK +I ++ + T++ + R SGKY L V+ ++A ++++++D PGPPQ +K
Sbjct: 15530 LDK--ASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLK 15587
Query: 940 IEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGN 999
+++V +V LTW PP DG + I Y ++K + + TV + H+TS + +L G
Sbjct: 15588 VKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGC 15647
Query: 1000 EYYFRVFSENMCGL---SEDATMTKESAVIARDGKI 1032
YYFRV +EN G+ +E A K S GKI
Sbjct: 15648 SYYFRVLAENEYGIGLPAETAESVKASERPLPPGKI 15683
Score = 219 bits (557), Expect = 2e-56
Identities = 163/601 (27%), Positives = 258/601 (42%), Gaps = 40/601 (6%)
Query: 430 LKPLKILTPLTDQTVNLGKEICLKCEI--SENIPGKWTKNGLPVQESDRLKVVHKGRIHK 487
L P KIL P T+ GK++ ++ + + KW K V S L V
Sbjct: 12525 LLPPKILMP-EQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSI 12583
Query: 488 LVIANALTEDEGDYVFAPDAYNVTLPAKVHVI-----DPPKIILDGLDADNTVTVIAGNK 542
L+I + +D G Y + + T K+ V+ PP+ D D D
Sbjct: 12584 LIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADAC-----S 12638
Query: 543 LRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLK 602
L IP+ + + G S +S V + + ++ + +
Sbjct: 12639 LSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEY-IFRVRAE 12697
Query: 603 NEAGEAHASIKVKVV-----DFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIE 657
N G + K+V P P VT+V D + W+ P DGGSPI+GY IE
Sbjct: 12698 NRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIE 12757
Query: 658 RKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAV 717
RK++ S W++ N L + T + ++EG+ Y RI+A+N G S PS P+
Sbjct: 12758 RKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMP 12817
Query: 718 TSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDL 777
PP V VT +TV++ W P H G + + GY +E C L
Sbjct: 12818 VDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEAC------------------KL 12859
Query: 778 PAEDWIVAN--KDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIE 835
P + W+ N I + ++T TGL A+ R A A S P S P+ +
Sbjct: 12860 PGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENV 12919
Query: 836 PPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ-INIRNSETDT 894
PP+I + +K + G V L GKP P ++WKKDG + + I +
Sbjct: 12920 PPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLC 12979
Query: 895 IIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTP 954
+ + R SG Y + + ++A+I ++++D+PGPP VKI ++ + L+W P
Sbjct: 12980 TLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEP 13039
Query: 955 PKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLS 1014
P +DG + IT Y + K + W V TS ++ +L+ G+EY FR+ +EN G+
Sbjct: 13040 PLEDGGSEITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVG 13099
Query: 1015 E 1015
+
Sbjct: 13100 D 13100
Score = 219 bits (557), Expect = 2e-56
Identities = 151/565 (26%), Positives = 257/565 (45%), Gaps = 42/565 (7%)
Query: 464 WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPD--AYNVTLPAKVHVIDP 521
W K+GLP++ES+ ++ L I NA E G Y D + +P V + P
Sbjct: 21225 WLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGP 21284
Query: 522 PK-----IILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTE 576
P I D + AD+ + L ++P +S + + + ++
Sbjct: 21285 PSKPKGPIRFDEIKADSVI-------LSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCS 21337
Query: 577 SYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVD-----FPDPPVAPTVTEV 631
S ++ V ++ +D + + +N G + + +V P PP P + V
Sbjct: 21338 SVARTTFKVPNLV-KDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNV 21396
Query: 632 GDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYE 691
D + W+ P YDGGS + G+ +E+K++ S W ++N + ++EG+ Y+
Sbjct: 21397 TSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQ 21456
Query: 692 VRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDG 751
R++A N+ G+S PS PS+ + ++ PP VT T+T++W PP G + + G
Sbjct: 21457 FRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVG 21516
Query: 752 YVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVK 811
Y +E +Q +E W+ N + + ++T+TGL + R+
Sbjct: 21517 YSIE--------KRQGNER-----------WVRCNFTDVSECQYTVTGLSPGDRYEFRII 21557
Query: 812 AVNAAGA-SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPE 870
A NA G S P S I+ ++ PP + I + GE++ + QG+P P
Sbjct: 21558 ARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPR 21617
Query: 871 LTWKKDGAEIDKN-QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQII 929
+TW KDG EI+K + I + T +F+R A R H G Y ++ K A I +++
Sbjct: 21618 VTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 21677
Query: 930 DRPGP-PQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRT 988
D PG ++ ++ GE + L W P +DG A IT Y I+K + + W + +
Sbjct: 21678 DTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQ 21737
Query: 989 SATITELVIGNEYYFRVFSENMCGL 1013
S T +L+ GNEY FRV + N G+
Sbjct: 21738 SYTAIKLINGNEYQFRVSAVNKFGV 21762
Score = 216 bits (551), Expect = 8e-56
Identities = 161/592 (27%), Positives = 267/592 (45%), Gaps = 52/592 (8%)
Query: 463 KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNV----TLPAKVHV 518
+W K + + RL++ L + +A+ D G+Y+ A NV ++ V V
Sbjct: 16204 QWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILK--AKNVAGERSVTVNVKV 16261
Query: 519 IDPP-----KIILDGLDADNTVTVIA-----GNKLRLEIPISGEPPPKAMWSRGDKAIME 568
+D P +++ G+ A+ G + + + +W+ D +
Sbjct: 16262 LDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQT 16321
Query: 569 GSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTV 628
S ++ + T I + G E E+ + PD P AP V
Sbjct: 16322 LSCKVTKLLEGNEYTFRIMAVNKYGVG--------EPLESEPVVAKNPFVVPDAPKAPEV 16373
Query: 629 TEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGV 688
T V D I+ WE PA DGGS ILGY +E++ K+ RW R + L E +IE
Sbjct: 16374 TTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENH 16433
Query: 689 AYEVRIFAVNAIGISKPSMPS---RPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIG 745
YE R+ A NA G+S+PS PS + P+ PP V +T ++V + W P + G
Sbjct: 16434 DYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPIYDG 16493
Query: 746 AAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDL-IDKTKFTITGLPTDA 804
+ GY++E C D+ +W + I+KT + L
Sbjct: 16494 GCEIQGYIVEKC------------------DVSVGEWTMCTPPTGINKTNIEVEKLLEKH 16535
Query: 805 KIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQ 864
+ R+ A+N AG E PI+V+E +E P I + L++ R G ++ L +P +
Sbjct: 16536 EYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIK 16595
Query: 865 GKPRPELTW-KKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETAS 923
G+P PE+ W K DG D I++ +S T + + R SGKY L ++ ++A
Sbjct: 16596 GRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLV--LDNVNRYDSGKYTLTLENSSGTKSAF 16653
Query: 924 IDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIE 983
+ ++++D P PP +K+ ++ ++V++TW PP DG + I Y ++K + + V+
Sbjct: 16654 VTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVT 16713
Query: 984 HYHRTSATITELVIGNEYYFRVFSENMCGL---SEDATMTKESAVIARDGKI 1032
+ H+ S I +L G YYFRV +EN G+ ++ A K + V GKI
Sbjct: 16714 NCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKI 16765
Score = 216 bits (550), Expect = 1e-55
Identities = 154/518 (29%), Positives = 249/518 (48%), Gaps = 36/518 (6%)
Query: 505 PDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDK 564
P N + AK +++ P+I LD + +V AG +++ IP G PPP W R D+
Sbjct: 20881 PIEMNEPVQAK-DILEAPEIDLD-VALRTSVIAKAGEDVQVLIPFKGRPPPTVTW-RKDE 20937
Query: 565 AIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHAS-IKVKVVDFPDPP 623
+ R E+ SS L I R+D+G Y + ++N GE +S + VKV+D P
Sbjct: 20938 KNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAAC 20997
Query: 624 VAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKK 683
V V + W+PP DGGSPI+ Y IE++ W ++ C T+F+
Sbjct: 20998 QKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHK-CSSTSFKLID 21056
Query: 684 MIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDH 743
+ E + R+ A N IGI +P + P V +P L++ T T+V + W PD
Sbjct: 21057 LSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDF 21116
Query: 744 IGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKT-KFTITGLPT 802
G + + YV+E +G + W A I KT + ++ L
Sbjct: 21117 DGGSVITEYVVERKGKGE------------------QTWSHAG---ISKTCEIEVSQLKE 21155
Query: 803 DAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIP 862
+ + RV A N G S+P PI VKE+I P++ + R+G V+L +P
Sbjct: 21156 QSVLEFRVFAKNEKGLSDPVTIG-PITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELP 21214
Query: 863 FQGKPRPELTWKKDGAEIDKNQ-INIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVET 921
++GKP+P ++W KDG + +++ + +E + I+ A++ H GKY V +D V
Sbjct: 21215 YKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYT--VILDNAVCR 21272
Query: 922 ASIDIQIIDRPGPPQI----VKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSME 977
++ I +I GPP ++ +++ ++V L+W P+D+G IT Y+I+K +
Sbjct: 21273 IAVPITVITL-GPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTN 21331
Query: 978 WFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1015
W V RT+ + LV EY FRV +EN G+S+
Sbjct: 21332 WKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQ 21369
Score = 214 bits (546), Expect = 3e-55
Identities = 142/494 (28%), Positives = 224/494 (45%), Gaps = 36/494 (7%)
Query: 573 IRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG-----EAHASIKVKVVDFPDPPVAPT 627
+ S P T I V+ I +N+ G ++ + P P PT
Sbjct: 9893 VHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPT 9952
Query: 628 VTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETT----FEPKK 683
V+ V + +NWE P YDGGSP+ GY++E K S RW R+N D K T ++
Sbjct: 9953 VSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKVTG 10012
Query: 684 MIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRP 740
+IEG Y+ R++A+NA G+ S+PS P P+A PP V T ++ + W P
Sbjct: 10013 LIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPP-FPKVTDWTKSSADLEWSP 10071
Query: 741 PDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGL 800
P G + + GY++EY EG E+W + TK +TGL
Sbjct: 10072 PLKDGGSKVTGYIVEYKEEGK------------------EEWEKGKDKEVRGTKLVVTGL 10113
Query: 801 PTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLV 860
A RV+AVN AG EP + I +K+ + P +++ ++ + G + ++
Sbjct: 10114 KEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRII 10173
Query: 861 IPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVE 920
GKP P +TW + + + + I + + + I+ +RSH G Y L K +
Sbjct: 10174 AYVSGKPPPTVTWNMNERTLPQ-EATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGER 10232
Query: 921 TASIDIQIIDRPGPPQIVKI-EDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF 979
+I + ++D PGP + ++ E+ LTW P+DDG + IT Y I+K + W
Sbjct: 10233 KKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWT 10292
Query: 980 TVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYE 1039
V R +AT+ L+ G Y+FR+ +EN G+ T E+ VI + + P E
Sbjct: 10293 PVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMG-PFVETSEALVIREPITVPERP--E 10349
Query: 1040 DFDFSEAPMFTQPL 1053
D + E T L
Sbjct: 10350 DLEVKEVTKNTVTL 10363
Score = 211 bits (537), Expect = 3e-54
Identities = 160/553 (28%), Positives = 257/553 (46%), Gaps = 70/553 (12%)
Query: 502 VFAPDAYNVTLPAKV--HVI--DP---PKIILDGLDADNTVTVIAGNKLRLEIPISGEPP 554
V A +A V+ P+++ +V+ DP P I L+ D + VI G KL + +P P
Sbjct: 7988 VRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHD----IIVIEGEKLSIPVPFRAVPV 8043
Query: 555 PKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKV 614
P W + K + + S R+ ++ S+ L + + R D+G+Y I L+N+ G A ASI V
Sbjct: 8044 PTVSWHKDGKEV-KASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINV 8102
Query: 615 KVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLC 674
KV+ P P +++ C + WEPP +DGG+PIL Y +ER++ ++ +
Sbjct: 8103 KVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGEN 8162
Query: 675 KETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTD 731
K ++ K +I Y R+ AVN +G + P + P PP + V + T
Sbjct: 8163 K-LSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTA 8221
Query: 732 TTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLID 791
+T+ W+PP + G + + GY++E +G E W N+ L+
Sbjct: 8222 EAMTITWKPPLYDGGSKIMGYIIEKIAKGE------------------ERWKRCNEHLVP 8263
Query: 792 KTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIR 851
+T GL + RV+A NAAG SEP + P + I+ PK+ + L+ ++
Sbjct: 8264 ILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLE---VK 8320
Query: 852 RVGEAVNLVIPFQGKPRPELTWKKD-----GAEIDK------------------------ 882
R G+ + L G P P +TW KD EI K
Sbjct: 8321 R-GDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLT 8379
Query: 883 NQINIRNSET-DTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIE 941
+++I NS+ ++ + +R + R G Y ++V+ D + A + ++D PGPP E
Sbjct: 8380 QRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFE 8439
Query: 942 DVWGENVALTWTPPKDDGNAAITGYTIQKAD--KKSMEWFTVIEHYHRTSATITELVIGN 999
D+ +V W PP DDG + I YT++K D K EW V ++T+L+ G
Sbjct: 8440 DIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGK 8499
Query: 1000 EYYFRVFSENMCG 1012
EY FRV +EN G
Sbjct: 8500 EYLFRVRAENRFG 8512
Score = 210 bits (535), Expect = 5e-54
Identities = 177/671 (26%), Positives = 293/671 (43%), Gaps = 79/671 (11%)
Query: 380 EIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPL 439
+++ G K +RIR + GA A + + + A P +L P
Sbjct: 13965 DLVEGGKYEFRIRAKNTA------GAISAPSESTETIICKDEYEA-------PTIVLDPT 14011
Query: 440 TDQ--TVNLGKEICLKCE--ISENIP-GKWTKNGLPVQESDRLKVVHKGRIHKLVIANAL 494
T+ G I L + + +P W+K G ++ SD ++ L I A
Sbjct: 14012 IKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYAT 14071
Query: 495 TEDEGDY-VFAPDAYNVTLP-AKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGE 552
+D G+Y + A + + + KV V+D P G ++ ++ K L +
Sbjct: 14072 RKDAGEYTITATNPFGTKVEHVKVTVLDVP-----GPPGPVEISNVSAEKATL----TWT 14122
Query: 553 PPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLK----NE---- 604
PP + S I+E ++S L+ + D H+ K NE
Sbjct: 14123 PPLEDGGSPIKSYILEKR---------ETSRLLWTVVSEDIQSCRHVATKLIQGNEYIFR 14173
Query: 605 --------AGEAHASIKVKVVDF---PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILG 653
GE S VK+VD P PP P V+ V + ++W+ P DGGS I G
Sbjct: 14174 VSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITG 14233
Query: 654 YFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV 713
Y +ER++K+S RW+R + + + EG YE R+ A N GI PS S +
Sbjct: 14234 YHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVL 14293
Query: 714 PLAVTSPPTLLTVDSVTDTT---VTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDEN 770
PP + VTDTT ++ W P + G + GYV+E+ G A D
Sbjct: 14294 MKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGD-EAWIKDTT 14352
Query: 771 GEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILV 830
G A + T+F + L T K R+ A+N AG EP +V
Sbjct: 14353 GTA----------------LRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIV 14396
Query: 831 KEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNS 890
+ + P + L++T + R G ++ + +P +G+P PE+TW KD + KN+ NI N+
Sbjct: 14397 EREMAPD-FELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINL-KNRANIENT 14454
Query: 891 ETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVAL 950
E+ T++ I + R +GK+ + ++ ++ ++++++D PGP ++ D+ ++V L
Sbjct: 14455 ESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTL 14514
Query: 951 TWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENM 1010
W P DG + IT Y ++K + + T H+ + +T L G EY+FRV +EN
Sbjct: 14515 HWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENE 14574
Query: 1011 CGLSEDATMTK 1021
G+ E T+
Sbjct: 14575 YGIGEPTETTE 14585
Score = 207 bits (527), Expect = 5e-53
Identities = 119/408 (29%), Positives = 212/408 (51%), Gaps = 24/408 (5%)
Query: 620 PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTF 679
P PP P VT++ + + W P DGGS I GYF+E++ K+S W ++ + ++T
Sbjct: 20694 PGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQ 20753
Query: 680 EPKKMIEGVAYEVRIFAVNAIG---ISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTM 736
+ + E Y+ R+ AVNA G S+PS + P+ PP + + T +++T+
Sbjct: 20754 KVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITL 20813
Query: 737 RWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWI-VANKDLIDKTKF 795
W P + G + + GYV+E +Q +E E+W V+ K + T++
Sbjct: 20814 GWSKPVYDGGSAVTGYVVEI--------RQGEE----------EEWTTVSTKGEVRTTEY 20855
Query: 796 TITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGE 855
++ L + RV AVN AG EP ++P+ K+I+E P+I + L+ + I + GE
Sbjct: 20856 VVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGE 20915
Query: 856 AVNLVIPFQGKPRPELTWKKDGAEIDKN-QINIRNSETDTIIFIRKAERSHSGKYDLQVK 914
V ++IPF+G+P P +TW+KD + + + +I N+++ +++ I + R+ +GKY L ++
Sbjct: 20916 DVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIE 20975
Query: 915 VD-KFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADK 973
+++++ ++++D P Q ++++ V V L W PP DG + I Y I+K D
Sbjct: 20976 NGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDA 21035
Query: 974 KSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTK 1021
W V TS + +L ++FRV +EN G+ E T+
Sbjct: 21036 TKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTE 21083
Score = 206 bits (525), Expect = 8e-53
Identities = 160/599 (26%), Positives = 279/599 (46%), Gaps = 50/599 (8%)
Query: 444 VNLGKEICLKCEI-SENIPGK-WTKNGLPVQESD-RLKVVHKGRIHKLVIANALTEDEGD 500
V+ G+ L+ +I + IP W+K+G ++E+ R+++ + LV+ + + D G
Sbjct: 18347 VHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 18406
Query: 501 YVFAPDAYNVT--LPAKVHVIDPP-----KIILDGLDAD------NTVTVIAGNKLRLEI 547
Y+ T +P V V+D P + + G+ A+ N G + I
Sbjct: 18407 YILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYI 18466
Query: 548 PISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGE 607
I + W++ + + ++ T+ P + + +A Y I E+G
Sbjct: 18467 -IEKRETSRLSWTQVSTEVQALNYKV-TKLLPGNEYIFRVMAVNK----YGIGEPLESGP 18520
Query: 608 AHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWM 667
A K P PP P V+ + D ++ W P DGG+ I GY +E++ K+ RW
Sbjct: 18521 VTACNPYKP---PGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWT 18577
Query: 668 RLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVD 727
+ N + + EG +YE R+ A NA G+ +PS PS + PP +
Sbjct: 18578 KCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNP 18637
Query: 728 SVTDT---TVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIV 784
VTDT +V++ W P + G A + GYV+E EAA A++W
Sbjct: 18638 KVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEV--------------KEAA----ADEWTT 18679
Query: 785 ANKDL-IDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPR 843
+ +FT+T L + + R+ A+N+ G EP ++ +E IEPP+I +
Sbjct: 18680 CTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDA 18739
Query: 844 HLKQTYIRRVGEAVNLVIPFQGKPRPELTWKK-DGAEIDKNQINIRNSETDTIIFIRKAE 902
L++ + R + L + +G+P PE+ W+K +G D+ QI + +S T++ I
Sbjct: 18740 DLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSS--FTMLVIDNVT 18797
Query: 903 RSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAA 962
R SG+Y+L ++ + +TA ++++++D P P + I +V ++V L+W PP DG A
Sbjct: 18798 RFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAK 18857
Query: 963 ITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTK 1021
IT Y ++K + + T+ + +T+ I L G YYFRV + N G+ A T+
Sbjct: 18858 ITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTE 18916
Score = 206 bits (524), Expect = 1e-52
Identities = 159/616 (25%), Positives = 268/616 (43%), Gaps = 73/616 (11%)
Query: 434 KILTPLTDQTVNLGKEICLKCEISENIPG----------KWTKNGLPVQESDRLKVVHKG 483
K++ P + V L + + +K + P KWT +G ++ + V
Sbjct: 11132 KLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDN 11191
Query: 484 RIHKLVIANALTEDEGDYVFAPD--AYNVTLPAKVHVID---PPKIILDGLDADNTVTVI 538
L I N L D G+Y A + T+ + V+D PP ++ LD
Sbjct: 11192 FSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPE---- 11247
Query: 539 AGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIR-----TESYPDSSTLVIDIAERDD 593
+ IS +PP S I+E + S + L I ++
Sbjct: 11248 -------HMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGC 11300
Query: 594 SGVYHINLKNEAG-----EAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGG 648
V+ + +N+ G ++ ++ P PP P VT++ ++ ++W P DGG
Sbjct: 11301 EYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGG 11360
Query: 649 SPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMP 708
SPI GY++ER++ + +W+R+N + F + EG YE R+FA N G+SKPS
Sbjct: 11361 SPITGYYMERREV-TGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPS 11419
Query: 709 SRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAK 765
S P P+ PP + + T + W P G + + GYV+E C + T+
Sbjct: 11420 SDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVE-CQKPGTA-- 11476
Query: 766 QSDENGEAAYDLPAEDWIVANKD-LIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYY 824
W NKD LI + F + GL + R+KA N G EP+
Sbjct: 11477 ---------------QWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPREL 11521
Query: 825 SQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ 884
++ ++ K+I+ PP++ + + RVG+ + ++ +G+P P++TW K+G +
Sbjct: 11522 AESVIAKDILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEG------K 11575
Query: 885 INIRNSETDTI-------IFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQI 937
+ +R D I + I++A R+ GKY + K S + ++DRPGP Q
Sbjct: 11576 VLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQN 11635
Query: 938 VKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVI 997
+K+ +V EN ++W P D+G + IT + ++ W V + L+
Sbjct: 11636 LKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIVASDVTKRLIK-ANLLA 11694
Query: 998 GNEYYFRVFSENMCGL 1013
NEYYFRV +EN G+
Sbjct: 11695 NNEYYFRVCAENKVGV 11710
Score = 204 bits (520), Expect = 3e-52
Identities = 127/423 (30%), Positives = 206/423 (48%), Gaps = 36/423 (8%)
Query: 611 SIKVKVVD---FPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWM 667
S KV + D P PP P V +++W PP +GGSPI GY++E++++ S W
Sbjct: 9215 SDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWS 9274
Query: 668 RLNFDLC-----KETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTS 719
R++ K F +++EGV Y+ R A+NA GI PS PS P V P+
Sbjct: 9275 RVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPG 9334
Query: 720 PPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPA 779
PP+ V T +++++ W+PP G + + GY++E EG+T K+ +E +
Sbjct: 9335 PPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDK------- 9387
Query: 780 EDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKI 839
LI + + L K RVKAVN AG SEP + I +I E P++
Sbjct: 9388 ---------LITTCECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEV 9438
Query: 840 RIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWK---------KDGAEIDKNQINIRNS 890
I + + + G + + +G+P P+ +W+ KDG + +
Sbjct: 9439 FIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETA 9498
Query: 891 ETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVAL 950
E ++I I + +RSH+GKY + K +TA+ ++++D PGPP+ +K+ D+ + L
Sbjct: 9499 ENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRL 9558
Query: 951 TWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENM 1010
+W P DDG I GY I+K W V T+ + +L+ +Y+FRV +EN
Sbjct: 9559 SWKMPDDDGGDRIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENR 9618
Query: 1011 CGL 1013
G+
Sbjct: 9619 FGI 9621
Score = 204 bits (518), Expect = 5e-52
Identities = 146/522 (27%), Positives = 236/522 (45%), Gaps = 39/522 (7%)
Query: 520 DPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYP 579
+PP + LD + + ++AG LR+ ++G P P +W++ + + R+ ++
Sbjct: 8728 EPPAVELD-VSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGEL--DKDRVVIDNVG 8784
Query: 580 DSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMN 639
S L+I A R D G Y I N G A+ +V+V D P P + C++N
Sbjct: 8785 TKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLN 8844
Query: 640 WEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNA 699
W P DGGS I G+ IERK + W R + + + + ++EG Y+ R+ A N
Sbjct: 8845 WSDPEDDGGSEITGFIIERKDAKMHTW-RQPIE-TERSKCDITGLLEGQEYKFRVIAKNK 8902
Query: 700 IGISKPSM--PSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 757
G P P PL + P LT T +T+T+ W+ P G + + GY++E
Sbjct: 8903 FGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIE-- 8960
Query: 758 FEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAG 817
+ +D P D+ NK L T F + L RVKAVN G
Sbjct: 8961 --------------KRRHDKP--DFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIG 9004
Query: 818 ASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIR-RVGEAVNLVIPFQGKPRPELTWKKD 876
SEP +++++ PP I++ ++ I+ + GE V++ G P P++ W K+
Sbjct: 9005 ESEPS-LPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKN 9063
Query: 877 GAEIDK-------NQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQII 929
I+K + + SE T + I KA R G Y + ++ +++
Sbjct: 9064 ETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVY 9123
Query: 930 DRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKAD--KKSMEWFTVIEHYHR 987
DRP PP+ + + D+ E+ LTW P D+G + IT Y I K D +K EW V
Sbjct: 9124 DRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVE 9183
Query: 988 TSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARD 1029
I +L+ +Y FRV + N G+S++ K V+ +D
Sbjct: 9184 KRYGIWKLIPNGQYEFRVRAVNKYGISDEC---KSDKVVIQD 9222
Score = 203 bits (516), Expect = 9e-52
Identities = 164/613 (26%), Positives = 270/613 (44%), Gaps = 62/613 (10%)
Query: 443 TVNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGD 500
T+ G ++ L + K WTK + +++ + + G+ VI D G
Sbjct: 22686 TIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGK 22745
Query: 501 YVFAPDAYNVT--LPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPP---- 554
Y + T + V V+D P G TV+ + K L + E
Sbjct: 22746 YTLTVKNASGTKAVSVMVKVLDSP-----GPCGKLTVSRVTQEKCTLAWSLPQEDGGAEI 22800
Query: 555 -----PKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG--- 606
+ SR + I+EG T SY V+ +++ ++ + N+ G
Sbjct: 22801 THYIVERRETSRLNWVIVEGE--CPTLSY------VVTRLIKNNEYIFRVRAVNKYGPGV 22852
Query: 607 --EAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSS 664
E+ + P PP P G + I+ W P DGG+ I Y +++++K+S
Sbjct: 22853 PVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSL 22912
Query: 665 RWMRLNFD-LCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV----PLAVTS 719
RW R+N D + +T + ++EG Y+ R+ AVNA G S+PS S F+ P
Sbjct: 22913 RWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASN-FISCREPSYTPG 22971
Query: 720 PPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPA 779
PP+ V T ++++ W P + G + GYVLE K +D+
Sbjct: 22972 PPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEM------QEKDTDQ---------- 23015
Query: 780 EDWI-VANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPK 838
W V I T+FT+ L K RV AVN G SE I E IE P
Sbjct: 23016 --WYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPD 23073
Query: 839 IRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFI 898
+ + LK+T R G ++ L++ G+P P +TW K G ++ I I +E+ +++ +
Sbjct: 23074 LELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAI-IDTTESYSLLIV 23132
Query: 899 RKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDD 958
K R +GKY ++ + ++A++ +++ D PGP VK+++V ++V +TW P D
Sbjct: 23133 DKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTID 23192
Query: 959 GNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE--- 1015
G A + Y ++K + + TV +T I+ LV G YYFRV EN+ G+ E
Sbjct: 23193 GGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCE 23252
Query: 1016 --DATMTKESAVI 1026
DA + E ++
Sbjct: 23253 TSDAVLVSEVPLV 23265
Score = 201 bits (512), Expect = 3e-51
Identities = 157/613 (25%), Positives = 280/613 (45%), Gaps = 46/613 (7%)
Query: 420 GQSSAKLSVDLKPLKILTPLTDQ-TVNLGKEICLKCEI-SENIPG-KWTKNGLPVQESDR 476
G +AK V+L + + D VN G+ L+ ++ + +P +W + ++ES R
Sbjct: 17240 GPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESAR 17299
Query: 477 LKVVHKGRIHKLVIANALTEDEGDYVFAPD--AYNVTLPAKVHVIDPPKIILDGLDADNT 534
++ + L++ +A+ D G Y+ A + + P V V+D P +
Sbjct: 17300 CEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRP----GPPEGPVQ 17355
Query: 535 VTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIR-----TESYPDSSTLVIDIA 589
VT + K L + PP + S ++E R S +++L +
Sbjct: 17356 VTGVTSEKCSL----TWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKL 17411
Query: 590 ERDDSGVYHINLKNE--AGEAHASIKVKVVD---FPDPPVAPTVTEVGDDWCIMNWEPPA 644
+ V+ I N+ GE S V + + P PP + VT + D + W P
Sbjct: 17412 LEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPD 17471
Query: 645 YDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISK 704
DGGS I+GY +E++ + RW++ N + + E YE R+ A NA G+ +
Sbjct: 17472 SDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGE 17531
Query: 705 PSMPS---RPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGS 761
PS + + P+ PPT + T ++T+ W P + G + + GYV+E C
Sbjct: 17532 PSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEIC---- 17587
Query: 762 TSAKQSDENGEAAYDLPAEDW-IVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASE 820
++DE E+W IV + + T+F I+ L + +RV A+N G E
Sbjct: 17588 ----KADE----------EEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGE 17633
Query: 821 PKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI 880
+ ++ +E P++ + L++ + R G + + IPF+G+P PE+TW ++ E
Sbjct: 17634 ATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEF 17693
Query: 881 DKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKI 940
+++ I T + I +R+ +GKY L+++ ++A + ++++D PGPPQ + +
Sbjct: 17694 T-DKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAV 17752
Query: 941 EDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNE 1000
++V ++ L W PP DG A + Y I K + + V +TS + L G
Sbjct: 17753 KEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAI 17812
Query: 1001 YYFRVFSENMCGL 1013
YYFRV +EN G+
Sbjct: 17813 YYFRVMAENEFGV 17825
Score = 201 bits (510), Expect = 4e-51
Identities = 139/497 (27%), Positives = 230/497 (46%), Gaps = 32/497 (6%)
Query: 620 PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTF 679
P P P V V + + WE P +DGGS I+GY++E+K++ + W++ N C E +
Sbjct: 22469 PSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNY 22528
Query: 680 EPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWR 739
+ ++EG+ Y+ R +A+NA G+SK S SRP + P V VT +TV++ W
Sbjct: 22529 KVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAPGRPEVTDVTRSTVSLIWS 22588
Query: 740 PPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITG 799
P + G + + GY++E K E G+ W+ N ++ FT+T
Sbjct: 22589 APAYDGGSKVVGYIIE--------RKPVSEVGDGR-------WLKCNYTIVSDNFFTVTA 22633
Query: 800 LPTDAKIFVRVKAVNAAGA-SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIR-RVGEAV 857
L RV A NAAG S+ + P+ ++ PPK + L + R G +
Sbjct: 22634 LSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDL 22693
Query: 858 NLVIPFQGKPRPELTWKKDGAEIDK-NQINIRNSETDTIIFIRKAERSHSGKYDLQVKVD 916
L GKP P++ W K E+D +++++ + I+ +RS SGKY L VK
Sbjct: 22694 VLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNA 22753
Query: 917 KFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSM 976
+ S+ ++++D PGP + + V E L W+ P++DG A IT Y +++ + +
Sbjct: 22754 SGTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRL 22813
Query: 977 EWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNP 1036
W V S +T L+ NEY FRV + N G + ++AR+ +P
Sbjct: 22814 NWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYG---PGVPVESEPIVARNSFTIPSP 22870
Query: 1037 --VYEDFDFSEAPM---FTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMK-NKVAIVDD 1090
+ E+ + + +T+P + G N N V K + W + NK +V D
Sbjct: 22871 PGIPEEVGTGKEHIIIQWTKPESD-----GGNEISNYLVDKREKKSLRWTRVNKDYVVYD 22925
Query: 1091 PRYRMFSNQGVCTLEIR 1107
R ++ S C + R
Sbjct: 22926 TRLKVTSLMEGCDYQFR 22942
Score = 196 bits (497), Expect = 1e-49
Identities = 219/924 (23%), Positives = 366/924 (39%), Gaps = 131/924 (14%)
Query: 263 QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 322
+V + V F E+ + KW++N + I S+KYI K L I + + D + Y
Sbjct: 6278 RVKEQQEVVFNCEVNTEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANY 6337
Query: 323 YVTAGDE-----KCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKN 377
V+ + K + L V E + + + L+D + V C+V+ + +KW KN
Sbjct: 6338 NVSLTNHRGENVKSAANLIVEEEDLRIVEPLKDIETMEKKSVTFWCKVNRLNVTLKWTKN 6397
Query: 378 GEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILT 437
GEE+ + YR V+ KH+L I+ D EY V +S A+L + P + +
Sbjct: 6398 GEEVPFDNRVSYR--VDKYKHMLTIKDCGFPDEGEYIVTAGQDKSVAELLIIEAPTEFVE 6455
Query: 438 PLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTE 496
L DQTV + C++S E KW +NG ++E + K G IH+L+I + +
Sbjct: 6456 HLEDQTVTEFDDAVFSCQLSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLD 6515
Query: 497 DEGDYVFAPD-----AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISG 551
DE +Y + A V +I PP+ IL+ AD V + NK ++E+
Sbjct: 6516 DECEYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGAD-VVFLAELNKDKVEV---- 6570
Query: 552 EPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHAS 611
W R + +++G + DI RD G Y K++ EA A
Sbjct: 6571 ------QWLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQ-GEYRFIAKDK--EARAK 6621
Query: 612 IKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYF-IERKKKQSSRWMRLN 670
+++ AP + D + D G P+ + K + W + N
Sbjct: 6622 LELAA--------APKIKTADQDLVV--------DVGKPLTMVVPYDAYPKAEAEWFKEN 6665
Query: 671 FDL--------CKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPT 722
L ++T+F + +G +I N G ++ + + + V P
Sbjct: 6666 EPLSTKTIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKV---IDVPGPVR 6722
Query: 723 LLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDW 782
L V D V++ W P G + + GYV+E D+ + W
Sbjct: 6723 NLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVE------------------RRDIKRKTW 6764
Query: 783 IVANKDLIDKTKFTITGLPTDAKIFV-RVKAVNAAGASEPKYYSQPILVKEIIEPPKIRI 841
++A D + +FT+TGL ++ RV A N G EP P+ + + P
Sbjct: 6765 VLAT-DRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVP---- 6819
Query: 842 PRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKD----GAEIDKNQINIRNSET---DT 894
G +N+ I + LTW+ GAEI I +R+ + DT
Sbjct: 6820 ------------GPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDT 6867
Query: 895 IIFIRKAERS-------HSGKYDLQVKVDKFV-----ETASIDIQI---IDRPGPPQIVK 939
+ +R + S +Y +V+ + A+ +++ I+RP PP +
Sbjct: 6868 AMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLT 6927
Query: 940 IEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV-IEHYHRTSATITELVIG 998
D +V L W PP DG + I GY I++ ++ W ++ + +T L G
Sbjct: 6928 SSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKG 6987
Query: 999 NEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYA 1058
N+Y +RV +EN G+S+ + + P+ D F E M +
Sbjct: 6988 NKYLYRVSAENKAGVSDPSEIL--------------GPLTADDAFVEPTMDLSAFKDGLE 7033
Query: 1059 IAGYNA-TLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTY 1117
+ N T+ G P+P TW + R +M + L I D G Y
Sbjct: 7034 VIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIY 7093
Query: 1118 CCKAVNDLGTVEIECKLEVKVIAQ 1141
K N + T+ E ++V VIA+
Sbjct: 7094 TLKLENRVKTISGE--IDVNVIAR 7115
Score = 195 bits (496), Expect = 2e-49
Identities = 141/519 (27%), Positives = 228/519 (43%), Gaps = 38/519 (7%)
Query: 518 VIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTES 577
++ PP++ LD + + +TV G +R+ + G P P W++ K ++ R +
Sbjct: 11530 ILHPPEVELD-VTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREK---RVDL 11585
Query: 578 YPDSSTLVIDIAE--RDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDW 635
D + + I E R D G Y I+ KN +G A S V V+D P P VT V +
Sbjct: 11586 IQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKEN 11645
Query: 636 CIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIF 695
C ++WE P +GGS I + +E +K W + D+ K ++ Y R+
Sbjct: 11646 CTISWENPLDNGGSEITNFIVEYRKPNQKGWSIVASDVTKRLI--KANLLANNEYYFRVC 11703
Query: 696 AVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGY 752
A N +G+ P + P+ P L + T V ++WR PD+ G + Y
Sbjct: 11704 AENKVGVGPTIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSY 11763
Query: 753 VLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKA 812
+E +GS +DW +K I +T + + + RV+
Sbjct: 11764 HVERRLKGS------------------DDWERVHKGSIKETHYMVDRCVENQIYEFRVQT 11805
Query: 813 VNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELT 872
N G S+ ++ ++VKE ++ P + + L + G+ + L +GKP PE+
Sbjct: 11806 KNEGGESD-WVKTEEVVVKEDLQKPVLDLK--LSGVLTVKAGDTIRLEAGVRGKPFPEVA 11862
Query: 873 WKKDGAEIDKNQ---INIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQII 929
W KD D + + I + + KA+RS GKY + A + ++
Sbjct: 11863 WTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVL 11922
Query: 930 DRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTS 989
D+PGP + +KI DV + + W PP+DDG I Y ++K + K M W T
Sbjct: 11923 DKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPG 11982
Query: 990 ATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIAR 1028
T+T L+ GNEY FRV +EN G T+ VIA+
Sbjct: 11983 TTVTRLIEGNEYIFRVRAENKIGTGPP---TESKPVIAK 12018
Score = 195 bits (495), Expect = 2e-49
Identities = 123/422 (29%), Positives = 206/422 (48%), Gaps = 28/422 (6%)
Query: 620 PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTF 679
P PP A V +V + WEPP DGG PI Y IE+K++ +RW++ + F
Sbjct: 7812 PGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNF 7871
Query: 680 EPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTM 736
+IEG + ++ A N G+ PS P+ P + SPP L V + +
Sbjct: 7872 RVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAI 7931
Query: 737 RWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFT 796
W+PP+ G + + GY +E C G+ E W+ N I KF
Sbjct: 7932 AWKPPEKNGGSPIIGYHVEMCPVGT------------------EKWMRVNSRPIKDLKFK 7973
Query: 797 IT-GLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGE 855
+ G+ D + +RV+AVNA G SEP S+ ++ K+ P I + H I GE
Sbjct: 7974 VEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETH---DIIVIEGE 8030
Query: 856 AVNLVIPFQGKPRPELTWKKDGAEID-KNQINIRNSETDTIIFIRKAERSHSGKYDLQVK 914
+++ +PF+ P P ++W KDG E+ +++ ++N + + K+ R+ +G Y + ++
Sbjct: 8031 KLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLE 8090
Query: 915 VDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKK 974
TASI++++I PGP + +K D+ + LTW PP+ DG I Y +++ +
Sbjct: 8091 NKLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAG 8150
Query: 975 SMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYK 1034
+ V+ ++ S T+ +L+ EY+FRV + N G E + ++ VIA+D K
Sbjct: 8151 RRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIEL--KNPVIAQDPKQPP 8208
Query: 1035 NP 1036
+P
Sbjct: 8209 DP 8210
Score = 194 bits (493), Expect = 4e-49
Identities = 148/575 (25%), Positives = 258/575 (44%), Gaps = 49/575 (8%)
Query: 464 WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAK----VHVI 519
W K+G+ +++ +++ L + +A + G V+ +A N + AK V V
Sbjct: 21620 WFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRG--VYTVEAKNASGSAKAEIKVKVQ 21677
Query: 520 DPPKIILDGLDADNTVTVIAGNKLRL--EIPISGEPPP-------KAMWSRGDKAIMEGS 570
D P ++ + N I G K+ L + P++ P K SR A++E
Sbjct: 21678 DTPGKVVGPIRFTN----ITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIED- 21732
Query: 571 GRIRTESYPDSSTLVIDIAERDDSGV--YHINLKNEAGEAHASIKVKVVDFPDPPVAPTV 628
+ +SY + + + S V + + ++ A I+ V PD P P
Sbjct: 21733 -KCEAQSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTV---PDAPGIPEP 21788
Query: 629 TEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMR-LNFDLCKETTFEPKKMIEG 687
+ + + + W P DGGS I Y +ER++K+S+RW++ ++ ET F+ + EG
Sbjct: 21789 SNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEG 21848
Query: 688 VAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHI 744
YE + A NA G+ S SR P+ PPT++ V + TTV++ W P
Sbjct: 21849 NEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFD 21908
Query: 745 GAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDA 804
G + GY++E C DW N + KT++T+T L
Sbjct: 21909 GGMEIIGYIIEMC------------------KADLGDWHKVNAEACVKTRYTVTDLQAGE 21950
Query: 805 KIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQ 864
+ RV A+N AG + + I + + P++ I + KQT++ R G ++ L I +Q
Sbjct: 21951 EYKFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQ 22010
Query: 865 GKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASI 924
G+P P W K + + + +I +++ + + + R+ +GKY L V+ + ++ +
Sbjct: 22011 GRPTPTAVWSKPDSNLSL-RADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITF 22069
Query: 925 DIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEH 984
++++D PGPP + +DV + L W P DG A I Y ++K + W + E
Sbjct: 22070 TVKVLDTPGPPGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEK 22129
Query: 985 YHRTSATITELVIGNEYYFRVFSENMCGLSEDATM 1019
R + +L G YYFRV + N G+ E M
Sbjct: 22130 CTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEM 22164
Score = 185 bits (470), Expect = 2e-46
Identities = 172/692 (24%), Positives = 288/692 (41%), Gaps = 92/692 (13%)
Query: 373 KWFKNGEEIIP-----------GPKSRYRIRVEGKKHILIIEGATKA-------DAAEYS 414
+W + E ++P G + ++R+R E I AT DA +
Sbjct: 8253 RWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVI 8312
Query: 415 VMTT-----GGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKC---------EISENI 460
+ T+ G + + S+ P +T + D+ V + +EI + E+ E
Sbjct: 8313 LRTSLEVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEE 8372
Query: 461 PGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYN--VTLPAKVHV 518
P LP+ + + KG +L + ++L D G Y+ + + P V V
Sbjct: 8373 PFV-----LPLTQRLSIDNSKKGE-SQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSV 8426
Query: 519 IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESY 578
+D P ++ + D T + EPP G I+ + + ++
Sbjct: 8427 LDTPGPPINFVFEDIRKTSVL---------CKWEPP----LDDGGSEIINYTLEKKDKTK 8473
Query: 579 PDSSTLVIDIAERD-----------DSGVYHINLKNEAGEAHASIKVKVVDF-----PDP 622
PDS +V+ R ++ + +N G + +V PD
Sbjct: 8474 PDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPFGPPDA 8533
Query: 623 PVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPK 682
P P V +V + ++ W P D GSPILGY++E+++ S+ W R+N L
Sbjct: 8534 PDKPIVEDVTSNSMLVKWNEPK-DNGSPILGYWLEKREVNSTHWSRVNKSLLNALKANVD 8592
Query: 683 KMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSP--PTLLTVDSVTDTTVTMRWRP 740
++EG+ Y R+ A NA G K S PS P SP P + V + TT+ + W P
Sbjct: 8593 GLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIELEWEP 8652
Query: 741 PDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGL 800
P G + GY ++ G+ +W + +I ++T+ +
Sbjct: 8653 PAFNGGGEIVGYFVDKQLVGT------------------NEWSRCTEKMIKVRQYTVKEI 8694
Query: 801 PTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLV 860
A +RV AVNAAG P +QP+ V E EPP + + +K G+ + +
Sbjct: 8695 REGADYKLRVSAVNAAGEGPPG-ETQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIP 8753
Query: 861 IPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVE 920
G+P P W K+ E+DK+++ I N T + + I+ A R G+Y + +
Sbjct: 8754 AVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSK 8813
Query: 921 TASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFT 980
A+ +++ D PGP +K + L W+ P+DDG + ITG+ I++ D K W
Sbjct: 8814 FAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQ 8873
Query: 981 VIEHYHRTSATITELVIGNEYYFRVFSENMCG 1012
IE R+ IT L+ G EY FRV ++N G
Sbjct: 8874 PIE-TERSKCDITGLLEGQEYKFRVIAKNKFG 8904
Score = 184 bits (467), Expect = 4e-46
Identities = 177/720 (24%), Positives = 313/720 (43%), Gaps = 79/720 (10%)
Query: 344 VTKQLEDTTAYCGERVELECE-VSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILII 402
+ K+++D T GE +L C+ V ++KW++ G+E+I K Y++ +G+ H L +
Sbjct: 24163 IRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRK--YKMSSDGRTHTLTV 24220
Query: 403 EGATKADAAEYSVMTTGG----QSSAKLSVDLKP-LKILTPLTDQTVN-LGKEICLKCE- 455
+ D Y+ + T ++S+KL + P PL ++ +G + L
Sbjct: 24221 MTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMY 24280
Query: 456 ISENIPGK-WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPA 514
I +P W +Q S+ + + + LV+ N + Y V L
Sbjct: 24281 IGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAG------KYKVQLSN 24334
Query: 515 KVHVIDPPKIILDGLDADN----TVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIME-- 568
+D ILD D T ++ L+ IS +PP S ++E
Sbjct: 24335 VFGTVDA---ILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKC 24391
Query: 569 -----GSGRIRTESYPDSSTLVIDIAERDDSGVY-HINLKNEAG-----EAHASIKVKV- 616
++ + + ++ ++++ E ++G Y ++ +N G E + + +K
Sbjct: 24392 EAKEGAEWQLVSSAISVTTCRIVNLTE--NAGYYFRVSAQNTFGISDPLEVSSVVIIKSP 24449
Query: 617 VDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKE 676
+ P P PT+T V D C++ W+PPA DGG+ I Y++E+++K+ ++W+ + + +E
Sbjct: 24450 FEKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRE 24509
Query: 677 TTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTM 736
T F K +IEG+ YE R+ N G S+ S S P P + + + + V
Sbjct: 24510 TVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRY 24569
Query: 737 RWRPPDHIGAAGLDGYVLEYCFEG----STSAKQSDENGEAAYDLPAEDWIVANKDLIDK 792
+ G ++++ +G + K + + Y
Sbjct: 24570 QSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYH---------------- 24613
Query: 793 TKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRR 852
+ I + D +V+A N G+ E+ P KI +P+ L+
Sbjct: 24614 -QLIIASVTDDDATVYQVRATNQGGSVSGT------ASLEVEVPAKIHLPKTLEGMGAVH 24666
Query: 853 V--GEAVNLVIPFQGKPRPELTWKKDGAEIDKN---QINIRNSETDTIIFIRKAERSHSG 907
GE V++ IPF GKP P +TW+K ID N Q+ + S T +++F ER +G
Sbjct: 24667 ALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFT-SLVFPNGVERKDAG 24725
Query: 908 KYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYT 967
Y + K ++ ++++ + D P PP+ VK+ DV ++V LTWT P DG + IT Y
Sbjct: 24726 FYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYI 24785
Query: 968 IQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE-----DATMTKE 1022
++K + W V T T+ L Y FRV +EN GLS+ + T+TKE
Sbjct: 24786 VEKCATTAERWLRV-GQARETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKE 24844
Score = 169 bits (427), Expect = 2e-41
Identities = 165/704 (23%), Positives = 284/704 (40%), Gaps = 93/704 (13%)
Query: 350 DTTAYCGERV-ELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKA 408
D CGE V E + EV+ + KW+ YR++ + +GA+K
Sbjct: 7260 DKWVACGEPVAETKMEVTGLEEG-KWYA------------YRVKALNR------QGASKP 7300
Query: 409 DAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGK--WTK 466
+ Q + ++ +D+K L LT V G +I L ++ K WTK
Sbjct: 7301 SRPTEEIQAVDTQEAPEIFLDVKLLAGLT------VKAGTKIELPATVTGKPEPKITWTK 7354
Query: 467 NGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNV----TLPAKVHVIDP- 521
+ +++ R+ + + + + I ++ D G Y+ +A NV T +V+V+D
Sbjct: 7355 ADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYII--EAVNVCGRATAVVEVNVLDKP 7412
Query: 522 -PKIILDGLDADNTVTVIAGNKLR-------LEIPISGEPPPKAMWSRGDKAIMEGSGRI 573
P D D N ++ N R + +W + + + + +
Sbjct: 7413 GPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFK- 7471
Query: 574 RTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGD 633
T+ P+ + AE +Y + +A A + D P PP +++
Sbjct: 7472 ATKLIPNKEYIFRVAAE----NMYGVGEPVQASPITAKYQ---FDPPGPPTRLEPSDITK 7524
Query: 634 DWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVR 693
D + W P DGGSPI GY++ER + +W+R N K+TT+ K + Y R
Sbjct: 7525 DAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFR 7584
Query: 694 IFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLD 750
+ A N G KPS + P + P+ PP TV V T+V + W P+H G A ++
Sbjct: 7585 VLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIE 7644
Query: 751 GYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRV 810
YV+E G+ ++W+ + + T+ + GL + RV
Sbjct: 7645 SYVIEMLKTGT------------------DEWVRVAEG-VPTTQHLLPGLMEGQEYSFRV 7685
Query: 811 KAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRP- 869
+AVN AG SEP S P+L +E + PP PR L+ I + + +P + P
Sbjct: 7686 RAVNKAGESEPSEPSDPVLCREKLYPPS--PPRWLEVINITKNTADLKWTVPEKDGGSPI 7743
Query: 870 -----------ELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKF 918
W+ + + + ++ R A + G+ D
Sbjct: 7744 TNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTE----- 7798
Query: 919 VETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEW 978
+E + + PGPP + + DV +V L W PPK+DG I Y I+K ++ W
Sbjct: 7799 IEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRW 7858
Query: 979 FTVIEHY-HRTSATITELVIGNEYYFRVFSENMCGLSEDATMTK 1021
+ + +T+++ G E F+V +EN G+ + T+
Sbjct: 7859 VKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTE 7902
Score = 162 bits (411), Expect = 1e-39
Identities = 110/364 (30%), Positives = 175/364 (48%), Gaps = 16/364 (4%)
Query: 264 VDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYY 323
V G F EL+ + V+WY G+++ PS K + +G L + + ++ D E
Sbjct: 5835 VTAGETATFDCELSYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQ 5894
Query: 324 VTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIP 383
+TA D K LFV+EPP+ TK LED T G LECEVS ++A VKWFKNG EI+
Sbjct: 5895 LTAKDFKTHANLFVKEPPVEFTKPLEDQTVEEGATAVLECEVSRENAKVKWFKNGTEILK 5954
Query: 384 GPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQT 443
K Y I +G+ L+I T D Y+ ++S L+V ++ L PLTD
Sbjct: 5955 SKK--YEIVADGRVRKLVIHDCTPEDIKTYTCDAKDFKTSCNLNVVPPHVEFLRPLTDLQ 6012
Query: 444 VNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV 502
V + +CE+S EN KW K+G +++ + ++ KG + LVI L +DE +Y
Sbjct: 6013 VREKEMARFECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEY- 6071
Query: 503 FAPDAYNVTLPAKVHVIDPPKII---LDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMW 559
+ + + V++ + L ++ T T+ KL E+ +P + +W
Sbjct: 6072 -SCEVRTARTSGMLTVLEEEAVFTKNLANIEVSETDTI----KLVCEV---SKPGAEVIW 6123
Query: 560 SRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDF 619
+GD+ I+E +GR + LVI A +D+G Y+ L + + + +F
Sbjct: 6124 YKGDEEIIE-TGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEF 6182
Query: 620 PDPP 623
P
Sbjct: 6183 ISKP 6186
Score = 152 bits (383), Expect = 2e-36
Identities = 107/326 (32%), Positives = 162/326 (49%), Gaps = 37/326 (11%)
Query: 519 IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESY 578
+DPP+I +D D T+ V AG +++ I G+P P W +GD+ + + R+ +S
Sbjct: 16166 VDPPRISMDPKYKD-TIVVHAGESFKVDADIYGKPIPTIQWIKGDQEL-SNTARLEIKST 16223
Query: 579 PDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTV-TEVGDDWCI 637
+++L + A R DSG Y + KN AGE ++ VKV+D P PP P V + V + C
Sbjct: 16224 DFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCT 16283
Query: 638 MNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDL----CKETTFEPKKMIEGVAYEVR 693
+ W+PP DGGS I+ Y +ER++ W ++ ++ CK T K++EG Y R
Sbjct: 16284 LAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVT-----KLLEGNEYTFR 16338
Query: 694 IFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLD 750
I AVN G+ +P + S P V P V P V +VT ++ + W P G + +
Sbjct: 16339 IMAVNKYGVGEP-LESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEIL 16397
Query: 751 GYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRV 810
GYVLE + D+ G W +K LI + + +TGL + RV
Sbjct: 16398 GYVLE----------KRDKEGIR--------WTRCHKRLIGELRLRVTGLIENHDYEFRV 16439
Query: 811 KAVNAAGASEPKYYSQPILVKEIIEP 836
A NAAG SEP S P ++ +P
Sbjct: 16440 SAENAAGLSEP---SPPSAYQKACDP 16462
Score = 150 bits (379), Expect = 7e-36
Identities = 100/328 (30%), Positives = 160/328 (48%), Gaps = 26/328 (7%)
Query: 522 PKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS 581
P++ L G+ V AG+ +++EIP+ G P P W +GD+ I++ + R+ E+ S
Sbjct: 14691 PELDLRGI-YQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQ-ILKQTQRVNFETTATS 14748
Query: 582 STLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT-VTEVGDDWCIMNW 640
+ L I+ R DSG Y + +N GE I ++V D P PP P EV D+ +W
Sbjct: 14749 TILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSW 14808
Query: 641 EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAI 700
+PP DGG PI Y +E ++ S+ W+ L + + TT++ ++ G+ Y+ R+ A N
Sbjct: 14809 DPPENDGGVPISNYVVEMRQTDSTTWVELATTVIR-TTYKATRLTTGLEYQFRVKAQNRY 14867
Query: 701 GISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 757
G+ P + S V P V PP V +VT ++T+ W P G + + GY +E
Sbjct: 14868 GVG-PGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVE-- 14924
Query: 758 FEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAG 817
+ + NG W +K L+ F +GL RV A N AG
Sbjct: 14925 --------RKERNGIL--------WQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAG 14968
Query: 818 ASEPKYYSQPILVKEIIEPPKIRIPRHL 845
S+P S+P+L + I+PP +P ++
Sbjct: 14969 KSKPSKPSEPMLALDPIDPPGKPVPLNI 14996
Score = 150 bits (379), Expect = 7e-36
Identities = 103/337 (30%), Positives = 165/337 (48%), Gaps = 25/337 (7%)
Query: 506 DAYNVTLPAKV-HVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDK 564
D + LP + ++PP+I + + +TV V AG+ L+++IPISG+P PK SR D
Sbjct: 20085 DPRELLLPVLIKEQLEPPEIDMKNFPS-HTVYVRAGSNLKVDIPISGKPLPKVTLSR-DG 20142
Query: 565 AIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPV 624
++ + R TE ++ T+ + + D+G Y I N +G A I + V+D P PP
Sbjct: 20143 VPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPT 20202
Query: 625 APTV-TEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKK 683
P V +++ ++ + WEPP YDGGS + Y + +++ ++ W ++ + + T + K
Sbjct: 20203 GPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVAR-TMMKVMK 20261
Query: 684 MIEGVAYEVRIFAVNAIGISK--PSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPP 741
+ G Y+ RI A N GIS S +P PP+ V +VT ++T+ W P
Sbjct: 20262 LTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEP 20321
Query: 742 DHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLP 801
G + + GY LE D N W ANK +I T F +T +
Sbjct: 20322 VSNGGSAVVGYHLE----------MKDRNSIL--------WQKANKLVIRTTHFKVTTIS 20363
Query: 802 TDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPK 838
RV A NAAG +P + S+P+L + EPP+
Sbjct: 20364 AGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACEPPR 20400
Score = 149 bits (377), Expect = 1e-35
Identities = 148/568 (26%), Positives = 234/568 (41%), Gaps = 60/568 (10%)
Query: 360 ELEC-EVSEDDANVKWFK----NGEEII-----------PGPKSRYRIRVEGKKHILIIE 403
ELE +S+D ++W K G+EI+ K + R++ K+ I
Sbjct: 24064 ELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQ--FTIG 24121
Query: 404 GATKADAAEYSVMT---TGGQSSAKLSVDLKPLK-------ILTPLTDQTVNLGKEICLK 453
G +A E+ V TG + ++ +K I + D T LG+ L
Sbjct: 24122 GLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLS 24181
Query: 454 CEI-SENIPG-KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY--VFAPDAYN 509
C+I +P KW + G + +S + K+ GR H L + EDEG Y + +
Sbjct: 24182 CQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGE 24241
Query: 510 VTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEG 569
V +K+ + P+ G G+ LRL + G P P W G K +++
Sbjct: 24242 VETSSKLLLQATPQFH-PGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQK-LLQN 24299
Query: 570 SGRIRTESYPDSSTLVI-DIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTV 628
S I E+ + LV+ ++ + +G Y + L N G A + V++ D PD P P V
Sbjct: 24300 SENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIV 24359
Query: 629 TE-VGDDWCIMNWEPPAYDGGSPILGYFIER-KKKQSSRWMRLNFDLCKETTFEPKKMIE 686
E + + +++W+PPA DGGS I Y +E+ + K+ + W +L TT + E
Sbjct: 24360 IEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEW-QLVSSAISVTTCRIVNLTE 24418
Query: 687 GVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDH 743
Y R+ A N GIS P S + P P T+ +VT + + W+PP
Sbjct: 24419 NAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAWKPPAS 24478
Query: 744 IGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTD 803
G A + Y LE ++ +N WI + I +T F++ L
Sbjct: 24479 DGGAKIRNYYLE--------KREKKQN----------KWISVTTEEIRETVFSVKNLIEG 24520
Query: 804 AKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPF 863
+ RVK N G SE S+PI K + L+ +R A LV
Sbjct: 24521 LEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNA-TLVCKV 24579
Query: 864 QGKPRPELTWKKDGAEIDKNQINIRNSE 891
G P+P + W + G EI + + R E
Sbjct: 24580 TGHPKPIVKWYRQGKEIIADGLKYRIQE 24607
Score = 148 bits (373), Expect = 3e-35
Identities = 104/358 (29%), Positives = 163/358 (45%), Gaps = 33/358 (9%)
Query: 491 ANALTEDEGDYVFAPDAYNVT---LPAKVHVIDPPKIILDGLDA----DNTVTVIAGNKL 543
A LTE + +Y F A N P+++ V+ ++ LD D +
Sbjct: 13570 AKDLTEGK-EYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNF 13628
Query: 544 RLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKN 603
RL+IPI G+P P W +G+ + + R+ ES ++TL++ ++ D+G Y I LKN
Sbjct: 13629 RLKIPIKGKPAPSVSWKKGEDPLATDT-RVSVESSAVNTTLIVYDCQKSDAGKYTITLKN 13687
Query: 604 EAGEAHASIKVKVVDFPDPPVAPT-VTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQ 662
AG +I +KVV P P P EV + + W PP DGGS I Y +E++
Sbjct: 13688 VAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSV 13747
Query: 663 SSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTS 719
+++W+ ++TTF ++ EG+ Y R+ A N G+ + + S P V P V
Sbjct: 13748 NNKWVTCA-SAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGE-GLKSEPIVARHPFDVPD 13805
Query: 720 PPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPA 779
P + V +V++ W P G + + GY LE+ S
Sbjct: 13806 APPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLL---------------- 13849
Query: 780 EDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPP 837
W ANK I F +TGL + RV A+N AG +P S+P++ + I+PP
Sbjct: 13850 --WKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPP 13905
Score = 145 bits (365), Expect = 3e-34
Identities = 110/374 (29%), Positives = 173/374 (46%), Gaps = 19/374 (5%)
Query: 263 QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 322
QV + RF EL+ +VKW+K+G EI+ KY KG RIL IN C + D++EY
Sbjct: 6012 QVREKEMARFECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEY 6071
Query: 323 YVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEII 382
+ S L V E + TK L + + ++L CEVS+ A V W+K EEII
Sbjct: 6072 SCEVRTARTSGMLTVLEEEAVFTKNLANIEVSETDTIKLVCEVSKPGAEVIWYKGDEEII 6131
Query: 383 PGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQ 442
RY I EG+K IL+I+ A DA Y+ ++ K+ V + ++ +
Sbjct: 6132 --ETGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNL 6189
Query: 443 TVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 501
+ G++ C IS E+ P +W ++ ++ D+ V+ G+ LV+ +A +D G Y
Sbjct: 6190 EILEGEKAEFVCSISKESFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTY 6249
Query: 502 VF----APDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKA 557
V A A ++T+ K+ ++ P K D V E+ G KA
Sbjct: 6250 VVMVGAARAAAHLTVIEKLRIVVPLK--------DTRVKEQQEVVFNCEVNTEG---AKA 6298
Query: 558 MWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVV 617
W R ++AI + S I + TL I A DD Y+++L N GE S +V
Sbjct: 6299 KWFRNEEAIFDSSKYIILQK-DLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSAANLIV 6357
Query: 618 DFPDPPVAPTVTEV 631
+ D + + ++
Sbjct: 6358 EEEDLRIVEPLKDI 6371
Score = 143 bits (360), Expect = 1e-33
Identities = 99/322 (30%), Positives = 145/322 (45%), Gaps = 23/322 (7%)
Query: 519 IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESY 578
ID P LD D + V AG LE I G+P P +WS+ K + E + R+ +S
Sbjct: 18330 IDAPNASLDPKYKD-VIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKST 18388
Query: 579 PDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT-VTEVGDDWCI 637
+TLV+ R D G Y + L N G I VKV+D P PP P VT V + C
Sbjct: 18389 IQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCY 18448
Query: 638 MNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAV 697
+ W PP DGG+ I Y IE+++ W +++ ++ + ++ K++ G Y R+ AV
Sbjct: 18449 LAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEV-QALNYKVTKLLPGNEYIFRVMAV 18507
Query: 698 NAIGISKP--SMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLE 755
N GI +P S P P PP+ V ++T ++ + W P G ++GY+LE
Sbjct: 18508 NKYGIGEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILE 18567
Query: 756 YCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNA 815
+ D+ G W NK + + +TGL RV A NA
Sbjct: 18568 ----------KRDKEGVR--------WTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENA 18609
Query: 816 AGASEPKYYSQPILVKEIIEPP 837
AG EP S + + PP
Sbjct: 18610 AGVGEPSEPSVFYRACDALYPP 18631
Score = 140 bits (352), Expect = 9e-33
Identities = 97/357 (27%), Positives = 171/357 (47%), Gaps = 39/357 (10%)
Query: 496 EDEGDYVF---APDAYNVTLPAK----VHVID---PPKIILDGLDADNTVTVIAGNKLRL 545
E++ Y F A A N++ P++ V ++ PP+I L + + +TV AG + L
Sbjct: 12885 EEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLS-VAMKSLLTVKAGTNVCL 12943
Query: 546 EIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEA 605
+ + G+P P W + D +++ + I+ + TL + R DSG Y I +N +
Sbjct: 12944 DATVFGKPMPTVSWKK-DGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSS 13002
Query: 606 GEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSR 665
G A+IK+KV+D P PP + + ++ D +++WEPP DGGS I Y +++++
Sbjct: 13003 GSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPN 13062
Query: 666 WMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGI-----SKPSMPSRPFVPLAVTSP 720
W +++ + T+ +K+IEG Y+ RI A N G+ ++P++ P+ P P
Sbjct: 13063 WAQVSATV-PITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDP 13121
Query: 721 PTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAE 780
P + ++T +T+ W+PP G + + GY+LE + A
Sbjct: 13122 P---VISNITKDHMTVSWKPPADDGGSPITGYLLE------------------KRETQAV 13160
Query: 781 DWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPP 837
+W N+ I + TGL + RV A+N AG +P S+ ++ PP
Sbjct: 13161 NWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPP 13217
Score = 139 bits (350), Expect = 2e-32
Identities = 112/414 (27%), Positives = 188/414 (45%), Gaps = 21/414 (5%)
Query: 270 VRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDE 329
+ F V + + KW KNG EI+ + K K L I N D ++Y AG
Sbjct: 2940 ITFEVTVNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKA 2999
Query: 330 KCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRY 389
+ L+V I K ++D +R ECEVSE D V+W K+ +E+ R
Sbjct: 3000 TSTATLYVEARHIEFRKHIKDIKVLEKKRAMFECEVSEPDITVQWMKDDQEL--QITDRI 3057
Query: 390 RIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKE 449
+I+ E H L+I +DA +Y+V+ G S+AKL V+ + ++I + + V +
Sbjct: 3058 KIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEKQR 3117
Query: 450 ICLKCEISE-NIPGKWTKNGLPV--QESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPD 506
++ E++E ++ W K+G+ + Q +R K V + RIH++ I+ D G+Y F
Sbjct: 3118 AVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAG 3177
Query: 507 AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAI 566
++ V+ +PP++ L VTV +G R ISG P PK W + ++ +
Sbjct: 3178 RNRSSVTLYVNAPEPPQV----LQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLL 3233
Query: 567 MEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG----EAHASIKVKVVDFPD- 621
G + + TL++ A +D+ VY KN+ G A S++V V PD
Sbjct: 3234 STGF-KCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQ 3292
Query: 622 --PPVAPTVTEVGDDWCIMNWEPPAY----DGGSPILGYFIERKKKQSSRWMRL 669
P P + D +P + G + ++ + KK + SR+ R+
Sbjct: 3293 EMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRM 3346
Score = 137 bits (344), Expect = 8e-32
Identities = 104/360 (28%), Positives = 172/360 (47%), Gaps = 10/360 (2%)
Query: 272 FVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKC 331
F VEL+ + VKW+KN Q + + + +G + + + D S+ V A
Sbjct: 5576 FTVELSHDNIRVKWFKNDQRLHTTRSVSMQDEGKTHSITFKDLSIDDTSQIRVEAMGMSS 5635
Query: 332 STELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRI 391
+L V E T +L+D T + V L+CE+S+ DA VKWFK+G+EI P + I
Sbjct: 5636 EAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISKADAPVKWFKDGKEIKPSKNA--VI 5693
Query: 392 RVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEIC 451
+ +GKK +LI++ A K+D +Y+ ++S KL ++ + +K++ PL V +
Sbjct: 5694 KADGKKRMLILKKALKSDIGQYTCDCGTDKTSGKLDIEDREIKLVRPLHSVEVMETETAR 5753
Query: 452 LKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNV 510
+ EISE +I W G + ++ ++ +G+IH LV+ N + G F A NV
Sbjct: 5754 FETEISEDDIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTGGVDF--QAANV 5811
Query: 511 TLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGS 570
A + V P++I L VTV AG + +S E P + +G K +E S
Sbjct: 5812 KSSAHLRV--KPRVI-GLLRPLKDVTVTAGETATFDCELSYEDIPVEWYLKGKK--LEPS 5866
Query: 571 GRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTE 630
++ S TL + + +D+G + K+ A+ +K V+F P TV E
Sbjct: 5867 DKVVPRSEGKVHTLTLRDVKLEDAGEVQLTAKDFKTHANLFVKEPPVEFTKPLEDQTVEE 5926
Score = 137 bits (344), Expect = 8e-32
Identities = 134/554 (24%), Positives = 209/554 (37%), Gaps = 88/554 (15%)
Query: 617 VDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKE 676
+D P PP PTV +VG +NW P +DGG+ I Y IE K + W+R+ +
Sbjct: 7609 IDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTT 7668
Query: 677 TTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTT 733
P M EG Y R+ AVN G S+PS PS P + L SPP L V ++T T
Sbjct: 7669 QHLLPGLM-EGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNT 7727
Query: 734 VTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKT 793
++W P+ G + + Y++E D+ + W + + D T
Sbjct: 7728 ADLKWTVPEKDGGSPITNYIVE------------------KRDVRRKGWQTVDTTVKD-T 7768
Query: 794 KFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRV 853
K T+T L + RV A NA G S+ +L K+ P
Sbjct: 7769 KCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTP---------------- 7812
Query: 854 GEAVNLVIPFQGKPRPELTW---KKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYD 910
G L + K +L W K DG + + + T R + + D
Sbjct: 7813 GPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGT----RWVKAGKTAGPD 7868
Query: 911 LQVKVDKFVETASIDIQI-----------------------IDRPGPPQIVKIEDVWGEN 947
+V +E + Q+ P PP + + D ++
Sbjct: 7869 CNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKH 7928
Query: 948 VALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITE--LVIGNEYYFRV 1005
+A+ W PP+ +G + I GY ++ + +W V + E +V EY RV
Sbjct: 7929 IAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRV 7988
Query: 1006 FSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNAT 1065
+ N G+SE + +++ V+A+D E D I G +
Sbjct: 7989 RAVNAIGVSEPSEISEN--VVAKDPDCKPTIDLETHDI-------------IVIEGEKLS 8033
Query: 1066 LNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDL 1125
+ R P P ++W K+ + R M ++ LE+ K D G Y N L
Sbjct: 8034 IPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKL 8093
Query: 1126 GTVEIECKLEVKVI 1139
G+ + VKVI
Sbjct: 8094 GSA--TASINVKVI 8105
Score = 136 bits (343), Expect = 1e-31
Identities = 105/376 (27%), Positives = 169/376 (44%), Gaps = 13/376 (3%)
Query: 247 EEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQ 306
+ K+ F + L +K F E ++P ++VKWYK+G E+ KY
Sbjct: 2123 QAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKV 2182
Query: 307 RILFINNCQMTDDSEY-YVTAGDE--KCSTELFVREPPIMVTKQLEDTTAYCGERVELEC 363
L I +D +Y V DE K + +L V + K+L+D ELEC
Sbjct: 2183 HFLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGELEC 2242
Query: 364 EVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSS 423
VS ++ KW+ N E+ +Y I + L ++ TK D EYS + G +++
Sbjct: 2243 IVSPENIEGKWYHNDVEL--KSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTT 2300
Query: 424 AKLSVDLKPLKILTPLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKVVHK 482
KL + +P+ IL L+DQ V G + L+ ++S E++ G W K+G VQ SDR+ +V
Sbjct: 2301 CKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVID 2360
Query: 483 GRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNK 542
+ H L+I + ED G+Y F A ++ +V V +D + V VI G K
Sbjct: 2361 KQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYS-----VDVITPLKDVNVIEGTK 2415
Query: 543 LRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLK 602
LE +S W D+ I + R++ LVI+ D G Y + +
Sbjct: 2416 AVLECKVSVPDVTSVKWYLNDEQI-KPDDRVQAIVKGTKQRLVINRTHASDEGPYKLIVG 2474
Query: 603 NEAGEAHASI-KVKVV 617
+ S+ K+K++
Sbjct: 2475 RVETNCNLSVEKIKII 2490
Score = 133 bits (335), Expect = 8e-31
Identities = 197/836 (23%), Positives = 326/836 (38%), Gaps = 110/836 (13%)
Query: 337 VREPPIMVTKQLEDTTAY-CGERVELECEVS-EDDANVKWFKNGEEIIPGPKSRYRIRVE 394
V P I V + +DT GE LE +VS ++W K+G+E+ ++ I++
Sbjct: 15084 VEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKEL--EGTAKLEIKIA 15141
Query: 395 GKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKC 454
L+ + +T+ D+ Y++ T AK ++K L P + + + + KC
Sbjct: 15142 DFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGP-PEGPLAVTEVTSEKC 15200
Query: 455 EISENIP-----GKWTKNGLPVQESDRL---KVVHKGRIHKLVIANALTEDEGDY-VFAP 505
+S P K + +E+ RL V + ++ KL + L +E + V A
Sbjct: 15201 VLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAV 15260
Query: 506 DAYNVTLPAKVHVI---------DPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPK 556
+ Y V P + + DPPK + VT I + + + G P
Sbjct: 15261 NKYGVGEPLESEPVLAVNPYGPPDPPK--------NPEVTTITKDSM---VVCWGHPDSD 15309
Query: 557 A-------MWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG--- 606
+ R DKA + ++ D V + E + + I +N AG
Sbjct: 15310 GGSEIINYIVERRDKAGQRWI-KCNKKTLTDLRYKVSGLTEGHEYE-FRIMAENAAGISA 15367
Query: 607 EAHASIKVKVVDF---PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQS 663
+ S K D P PP P V + + W P YDGGS I GY +E +
Sbjct: 15368 PSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEE 15427
Query: 664 SRWMRLNFDL-CKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSM-PSRPFVPLAVTSPP 721
W + K T++ + E Y++RI+A+N+ G+ +P++ P P + P
Sbjct: 15428 DEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPE 15487
Query: 722 TLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAED 781
L D T+ + G +++ + S ++ ++Y L
Sbjct: 15488 IELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESLDKASIESTSSYTL---- 15543
Query: 782 WIVANKDLIDKTKF--TITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEII----- 834
IV N + D K+ T+ FV V+ ++ G Q + VKE+
Sbjct: 15544 LIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPP------QDLKVKEVTKTSVT 15597
Query: 835 ---EPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSE 891
+PP + +K YI E+ + +WK D + E
Sbjct: 15598 LTWDPPLLDGGSKIKN-YIVEKRESTRKAYSTVATNCHKTSWKVDQLQ-----------E 15645
Query: 892 TDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALT 951
+ F AE + + ETA ++ +RP PP + + DV +V+L+
Sbjct: 15646 GCSYYFRVLAENEYG--------IGLPAETAE-SVKASERPLPPGKITLMDVTRNSVSLS 15696
Query: 952 WTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMC 1011
W P+ DG + I GY ++ K S +W T T ATIT L+ G EY FRV ++N
Sbjct: 15697 WEKPEHDGGSRILGYIVEMQTKGSDKWATCAT-VKVTEATITGLIQGEEYSFRVSAQNEK 15755
Query: 1012 GLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI-AGYNATLNCSV 1070
G+S+ ++ VIA+D I P + L NT+ + AG + ++
Sbjct: 15756 GISDPRQLSVP--VIAKDLVI--------------PPAFKLLFNTFTVLAGEDLKVDVPF 15799
Query: 1071 RGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLG 1126
G P P +TW K+ V + R S + L I+ D G Y K N G
Sbjct: 15800 IGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAG 15855
Score = 133 bits (335), Expect = 8e-31
Identities = 89/320 (27%), Positives = 152/320 (47%), Gaps = 26/320 (8%)
Query: 522 PKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS 581
P L G+ + +T AG+ +++PISG P PK W + + E + R+ + D
Sbjct: 22273 PTADLTGI-TNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKE-TDRVSITTTKDR 22330
Query: 582 STLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT-VTEVGDDWCIMNW 640
+TL + + R DSG Y + L+N AG S+ V V+ P P P V+ V + C+++W
Sbjct: 22331 TTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLSW 22390
Query: 641 EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAI 700
P GG+ I Y +E+++ ++ W +N + K T + + + + Y R+ + N
Sbjct: 22391 GEPKDGGGTEITNYIVEKRESGTTAWQLVNSSV-KRTQIKVTHLTKYMEYSFRVSSENRF 22449
Query: 701 GISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 757
G+SKP + S P + P S PT V V+ +++RW P H G + + GY +E
Sbjct: 22450 GVSKP-LESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVE-- 22506
Query: 758 FEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAG 817
+ + N W+ NK + + +TGL + R A+NAAG
Sbjct: 22507 --------KKERNTIL--------WVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAG 22550
Query: 818 ASEPKYYSQPILVKEIIEPP 837
S+ S+PI+ + ++ P
Sbjct: 22551 VSKASEASRPIMAQNPVDAP 22570
Score = 131 bits (329), Expect = 4e-30
Identities = 159/630 (25%), Positives = 262/630 (41%), Gaps = 95/630 (15%)
Query: 267 GGRVRFVVELAD-PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVT 325
GG +R V + P EVKW K EIR + I + L ++N D +Y +T
Sbjct: 16585 GGSLRLFVPIKGRPTPEVKWGKVDGEIRDAA--IIDVTSSFTSLVLDNVNRYDSGKYTLT 16642
Query: 326 AGDEKCSTELFVR-------EPPI--MVTKQLEDTTAYCGERVELECE-------VSEDD 369
+ + FV PP+ VT+ +D+ + E L+ V + +
Sbjct: 16643 LENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKRE 16702
Query: 370 ANVKWF--------KNG---EEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTT 418
A K + KN +++ G +R+ E + I A A+ +
Sbjct: 16703 ATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGI-----GLPAQTADPIKVAE 16757
Query: 419 GGQSSAKLSVDLKPLKILTPLTDQTVNLG---KEICLKCEISENIPGKWTKNGLPVQESD 475
Q K++VD +T +V+L E +I + I K+ E
Sbjct: 16758 VPQPPGKITVD--------DVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECA 16809
Query: 476 RLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYN-----------VTLPAKVHVIDPPKI 524
R+K + + VI N LT+ E +Y+F A N V + AK VI+P
Sbjct: 16810 RVKSL------QAVITN-LTQGE-EYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEP--- 16858
Query: 525 ILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTL 584
D A ++ +V G L++E+PISG P P W++ D ++ + RI D +TL
Sbjct: 16859 --DVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTK-DGLPLKQTTRINVTDSLDLTTL 16915
Query: 585 VIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT-VTEVGDDWCIMNWEPP 643
I +DD G Y I + N G+ ASI++ +D PDPP P +V + ++W PP
Sbjct: 16916 SIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPP 16975
Query: 644 AYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGIS 703
Y GG I Y ++++ ++ W ++ + + TT + K+ G Y+ RIFA N G S
Sbjct: 16976 LYTGGCQITNYIVQKRDTTTTVWDVVSATVAR-TTLKVTKLKTGTEYQFRIFAENRYGQS 17034
Query: 704 KPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEG 760
++ S P V P PP +++ ++ ++W P + G + + GY LE
Sbjct: 17035 F-ALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLE----- 17088
Query: 761 STSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASE 820
+ + N W NK +I T+F L + RV A N G +
Sbjct: 17089 -----RKERNSIL--------WTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGK 17135
Query: 821 PKYYSQPILVKEIIEPPKIRIPRHLKQTYI 850
S+ + ++ +PP P +K+ I
Sbjct: 17136 ASKNSECYVARDPCDPPGTPEPIMVKRNEI 17165
Score = 131 bits (329), Expect = 4e-30
Identities = 92/316 (29%), Positives = 146/316 (46%), Gaps = 25/316 (7%)
Query: 521 PPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPD 580
PPK LD + VT+ AG+ L L+ + G+P PK +W++GDK ++ ++ +
Sbjct: 22671 PPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKE-LDLCEKVSLQYTGK 22729
Query: 581 SSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNW 640
+T VI +R DSG Y + +KN +G S+ VKV+D P P TV+ V + C + W
Sbjct: 22730 RATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAW 22789
Query: 641 EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAI 700
P DGG+ I Y +ER++ W+ + + C ++ ++I+ Y R+ AVN
Sbjct: 22790 SLPQEDGGAEITHYIVERRETSRLNWVIVEGE-CPTLSYVVTRLIKNNEYIFRVRAVNKY 22848
Query: 701 GISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 757
G P + S P V + SPP + + ++W P+ G + Y+++
Sbjct: 22849 GPGVP-VESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKR 22907
Query: 758 FEGSTSAKQSDENGEAAYDLPAEDWIVANKD-LIDKTKFTITGLPTDAKIFVRVKAVNAA 816
+ S W NKD ++ T+ +T L RV AVNAA
Sbjct: 22908 EKKSLR------------------WTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAA 22949
Query: 817 GASEPKYYSQPILVKE 832
G SEP S I +E
Sbjct: 22950 GNSEPSEASNFISCRE 22965
Score = 130 bits (328), Expect = 5e-30
Identities = 80/234 (34%), Positives = 120/234 (51%), Gaps = 8/234 (3%)
Query: 272 FVVELADPKLE-VKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEK 330
F VEL P ++ V+W KNG + + KY KG L I NC + D+S Y G
Sbjct: 2680 FTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGFRLGRLG 2739
Query: 331 CSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYR 390
S L V + + K+ +D TA V E VS D VKWF EI P K +R
Sbjct: 2740 ASARLHVET--VKIIKKPKDVTALENATVAFEVSVSHDTVPVKWFHKSVEIKPSDK--HR 2795
Query: 391 IRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEI 450
+ E K H L+++ + +DA EY+ + GQ K + ++ L I + + V K
Sbjct: 2796 LVSERKVHKLMLQNISPSDAGEYTAVV--GQLECKAKLFVETLHITKTMKNIEVPETKTA 2853
Query: 451 CLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF 503
+CE+S N+P W KNG+ ++ S++ K+V +G++H+L+I N TED +Y F
Sbjct: 2854 SFECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTF 2907
Score = 130 bits (328), Expect = 5e-30
Identities = 91/320 (28%), Positives = 147/320 (45%), Gaps = 24/320 (7%)
Query: 522 PKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS 581
P I+ G + + + + +G LR++ + G P P+ W + D +E + S
Sbjct: 21583 PPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFK-DGVEIEKRMNMEITDVLGS 21641
Query: 582 STLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT-VTEVGDDWCIMNW 640
++L + A RD GVY + KN +G A A IKVKV D P V P T + + + W
Sbjct: 21642 TSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWW 21701
Query: 641 EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAI 700
+ P DG +PI Y IE+++ W + D C+ ++ K+I G Y+ R+ AVN
Sbjct: 21702 DAPLNDGCAPITHYIIEKRETSRLAWALIE-DKCEAQSYTAIKLINGNEYQFRVSAVNKF 21760
Query: 701 GISKP--SMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCF 758
G+ +P S P + V P + ++T ++T+ W P+ G + + Y+LE
Sbjct: 21761 GVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERRE 21820
Query: 759 EGSTSAKQSDENGEAAYDLPAEDWI-VANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAG 817
+ ST W+ V +K I +T+F +TGL + V A NAAG
Sbjct: 21821 KKSTR------------------WVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAG 21862
Query: 818 ASEPKYYSQPILVKEIIEPP 837
S+ I +E + PP
Sbjct: 21863 VGPASGISRLIKCREPVNPP 21882
Score = 128 bits (322), Expect = 3e-29
Identities = 101/352 (28%), Positives = 164/352 (46%), Gaps = 15/352 (4%)
Query: 264 VDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYY 323
V +G FV EL+ K+ V W+KN ++ S + +G L + + D S+
Sbjct: 5213 VKEGETATFVCELSHEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIK 5272
Query: 324 VTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIP 383
+ + +L V E T +L D TA + + L+CEVS+ D VKWFK+GEEI+P
Sbjct: 5273 AQVKELSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSK-DVPVKWFKDGEEIVP 5331
Query: 384 GPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQT 443
PK Y I+ +G + IL I+ A D EY ++ A ++V+ + +K+ PL
Sbjct: 5332 SPK--YSIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPLYGVE 5389
Query: 444 VNLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV 502
V +G+ + E+SE ++ G+W G P+ S +++ G+ H L++ N G+
Sbjct: 5390 VFVGETAHFEIELSEPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTGEVS 5449
Query: 503 FAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRG 562
F A N A + V + P I + L + V V ++ + E +S E P W +G
Sbjct: 5450 F--QAANAKSAANLKVKELPLIFITPL---SDVKVFEKDEAKFECEVSRE-PKTFRWLKG 5503
Query: 563 DKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKV 614
+ I G R ++VI A +D Y EA + H S K+
Sbjct: 5504 TQEI-TGDDRFELIKDGTKHSMVIKSAAFEDEAKYMF----EAEDKHTSGKL 5550
Score = 127 bits (319), Expect = 6e-29
Identities = 199/857 (23%), Positives = 322/857 (37%), Gaps = 121/857 (14%)
Query: 319 DSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAY-CGERVELECEV-SEDDANVKWFK 376
DS +TA DE V P I + + DT GE LE +V + ++W +
Sbjct: 17237 DSTGPITAKDE-------VELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLR 17289
Query: 377 NGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKIL 436
+EI +R I+ K +LI++ A + D +Y + + S V++K L
Sbjct: 17290 GDKEI--EESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRP 17347
Query: 437 TPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVVHKGRIHKL-------- 488
P + V + KC ++ + P + G + VV K +L
Sbjct: 17348 GP-PEGPVQVTGVTSEKCSLTWSPPLQ--DGGSDISHY----VVEKRETSRLAWTVVASE 17400
Query: 489 VIANALTEDE----GDYVF---APDAYNVTLPAK-VHVIDPPKIILDGLDADNTVTVIAG 540
V+ N+L + +YVF A + Y V P + V+ +L G VT IA
Sbjct: 17401 VVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAK 17460
Query: 541 NKLRLEIPISGEPPPKAMWSRGDKA--------IMEGSGRIRTESYPDSSTLVIDIAER- 591
+ + + W+R D I+E R + + D+ R
Sbjct: 17461 DSMTV------------CWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRV 17508
Query: 592 -----DDSGVYHINLKNEAGEAH---ASIKVKVVD---FPDPPVAPTVTEVGDDWCIMNW 640
D + ++ +N AG A++ K D P PP + + + + W
Sbjct: 17509 TGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAW 17568
Query: 641 EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDL-CKETTFEPKKMIEGVAYEVRIFAVNA 699
P YDGGS ILGY +E K W + + T FE K+ E Y++R+ A+N
Sbjct: 17569 GKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNK 17628
Query: 700 IGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFE 759
+G+ + + P P L +DS + +R A G + +
Sbjct: 17629 VGLGEATSVPGTVKPEDKLEAPEL-DLDSELRKGIVVR--------AGGSARIHIPFKGR 17679
Query: 760 GSTSAKQSDENGEAAYDLPAEDWI------VANKDLIDKTKFTIT--GLPTDAKIFVRVK 811
+ S E GE + E + + N D D K+ + FV VK
Sbjct: 17680 PTPEITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVK 17739
Query: 812 AVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPEL 871
++ G Q + VKE+ + + + I + N VI + R
Sbjct: 17740 VLDTPGPP------QNLAVKEVRKDSAFLV---WEPPIIDGGAKVKNYVIDKRESTRK-- 17788
Query: 872 TWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDR 931
+ ++ K + N I + R + G V VET ++ +
Sbjct: 17789 AYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFG-------VGVPVETVDA-VKAAEP 17840
Query: 932 PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSAT 991
P PP V + DV + +L W P+ DG + + GY ++ K + +W V E +A
Sbjct: 17841 PSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAES-KVCNAV 17899
Query: 992 ITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQ 1051
+T L G EY FRV + N G S+ + VIA+D I P
Sbjct: 17900 VTGLSSGQEYQFRVKAYNEKGKSDPRVLGVP--VIAKDLTIQ-------------PSLKL 17944
Query: 1052 PLVNTYAI-AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPS 1110
P NTY+I AG + + V G P+P I+W+K+ + R + L I++ +
Sbjct: 17945 PF-NTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGN 18003
Query: 1111 PYDGGTYCCKAVNDLGT 1127
D G Y A N GT
Sbjct: 18004 KDDFGKYTVTATNSAGT 18020
Score = 126 bits (316), Expect = 1e-28
Identities = 125/552 (22%), Positives = 221/552 (40%), Gaps = 66/552 (11%)
Query: 597 YHINLKNEAG---EAHASIKVKVVD---FPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSP 650
Y + +N AG + S ++ D P PP P + + G + W P +DGG+P
Sbjct: 19683 YRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAP 19742
Query: 651 ILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSR 710
I GY +E KK + W + + + T + + G Y R+ +VN +G S PS S
Sbjct: 19743 ITGYTVEYKKSDDTDW-KTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSD 19801
Query: 711 PFVPLAVTSPP----------TLLTVDSVTDT-TVTMRWRPPDHIGAAGLDGYVLEYCFE 759
P + P TL+ + T TV R RP ++ + D + +
Sbjct: 19802 PQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYV 19861
Query: 760 GSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGAS 819
+T ++ S L E+ AN++ K TI + + A + + VK ++ G
Sbjct: 19862 DTTDSRTS---------LTIEN---ANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGPP 19909
Query: 820 EPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAE 879
I V+++ + + L G A + + + W
Sbjct: 19910 TN------ITVQDVTKESAV-----LSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNN 19958
Query: 880 IDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVK 939
++ + N + I + R SG+ + V + ET ++I ++P PP+ +
Sbjct: 19959 CNRLSYKVTNLQEGAIYYFRV-----SGENEFGVGIP--AETKE-GVKITEKPSPPEKLG 20010
Query: 940 IEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF--TVIEHYHRTSATITELVI 997
+ + ++V+LTW P+ DG + I Y ++ +K W V + H + + E
Sbjct: 20011 VTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKCAVAKSTHHVVSGLRE--- 20067
Query: 998 GNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTY 1057
+EY+FRVF+EN GLS+ + + + E + E M P Y
Sbjct: 20068 NSEYFFRVFAENQAGLSDPREL------------LLPVLIKEQLEPPEIDMKNFPSHTVY 20115
Query: 1058 AIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTY 1117
AG N ++ + G P PK+T ++ V + R+ T+ +++ D G Y
Sbjct: 20116 VRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRY 20175
Query: 1118 CCKAVNDLGTVE 1129
A N GT +
Sbjct: 20176 EITAANSSGTTK 20187
Score = 125 bits (315), Expect = 2e-28
Identities = 87/266 (32%), Positives = 123/266 (46%), Gaps = 11/266 (4%)
Query: 247 EEKKSAAFAKIL--DPAYQV---DKGGRVRFVVEL---ADPKLEVKWYKNGQEIRPSTKY 298
+E S A K+L DP + V DK + + L + VKW+K+G+EI PS KY
Sbjct: 5276 KELSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSKDVPVKWFKDGEEIVPSPKY 5335
Query: 299 IFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGER 358
+ G +RIL I + D EY G +K + V I V K L + GE
Sbjct: 5336 SIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPLYGVEVFVGET 5395
Query: 359 VELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTT 418
E E+SE D + +W G+ + P I +GKKHILI+ E S
Sbjct: 5396 AHFEIELSEPDVHGQWKLKGQPLTASPDC--EIIEDGKKHILILHNCQLGMTGEVSFQAA 5453
Query: 419 GGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRL 477
+S+A L V PL +TPL+D V E +CE+S E +W K + DR
Sbjct: 5454 NAKSAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPKTFRWLKGTQEITGDDRF 5513
Query: 478 KVVHKGRIHKLVIANALTEDEGDYVF 503
+++ G H +VI +A EDE Y+F
Sbjct: 5514 ELIKDGTKHSMVIKSAAFEDEAKYMF 5539
Score = 124 bits (312), Expect = 4e-28
Identities = 135/548 (24%), Positives = 203/548 (37%), Gaps = 95/548 (17%)
Query: 620 PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDL-CKETT 678
P PP P V + ++W PAYDGGSPI+GY +E K+ S W+R N ++T
Sbjct: 13217 PGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTR 13276
Query: 679 FEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPP----------TLLTVDS 728
FE ++E Y+ R++AVN IG S PS P + PP TL+
Sbjct: 13277 FEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAG 13336
Query: 729 VTDTT-VTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANK 787
VT V ++ RPP P W N
Sbjct: 13337 VTMRLYVPVKGRPP------------------------------------PKITWSKPNV 13360
Query: 788 DLIDKTKFTITGLPTDAKIFVRVKAVNAAGASE----------PKYYSQPILVKEIIEPP 837
+L D+ I TD F+R + VN A + K Y+ + V + PP
Sbjct: 13361 NLRDRIGLDIKS--TDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPP 13418
Query: 838 -KIRIPRHLKQT--------YIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIR 888
+ + K + I +N V+ Q + +W E K +
Sbjct: 13419 VNVTVKEISKDSAYVTWEPPIIDGGSPIINYVV--QKRDAERKSWSTVTTECSKTSFRVA 13476
Query: 889 NSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENV 948
N E F R + G D D ++ PGP +K+ V +
Sbjct: 13477 NLEEGKSYFFRVFAENEYGIGDPGETRDA--------VKASQTPGPVVDLKVRSVSKSSC 13528
Query: 949 ALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSE 1008
++ W P DG + I GY + +++ +W V++ + +L G EY FRV +E
Sbjct: 13529 SIGWKKPHSDGGSRIIGYVVDFLTEEN-KWQRVMKSLS-LQYSAKDLTEGKEYTFRVSAE 13586
Query: 1009 NMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNC 1068
N G + +T V+ARD + V D D P A N L
Sbjct: 13587 NENGEGTPSEIT----VVARD-----DVVAPDLDLKGLPDLCY-----LAKENSNFRLKI 13632
Query: 1069 SVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTV 1128
++G P P ++W K + + D R + S+ TL + D G Y N GT
Sbjct: 13633 PIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTK 13692
Query: 1129 EIECKLEV 1136
E ++V
Sbjct: 13693 EGTISIKV 13700
Score = 120 bits (301), Expect = 7e-27
Identities = 130/513 (25%), Positives = 208/513 (40%), Gaps = 41/513 (7%)
Query: 96 KGKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSF 155
KG+W+ + GKHL L S + + I K + G Y TYK S
Sbjct: 2603 KGEWL----RDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEY----TYKVATSKTSA 2654
Query: 156 DLEVH--ESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWEL 213
L+V + T N+ + + + +K V + E+ + V
Sbjct: 2655 KLKVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISV--- 2711
Query: 214 LKNAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVD--KGGRVR 271
K + Y I D RL R+ + KI+ V + V
Sbjct: 2712 ----KGTIYSLRIKNCAIVDESVYGFRLGRLGASARLHVETVKIIKKPKDVTALENATVA 2767
Query: 272 FVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKC 331
F V ++ + VKW+ EI+PS K+ + L + N +D EY G +C
Sbjct: 2768 FEVSVSHDTVPVKWFHKSVEIKPSDKHRLVSERKVHKLMLQNISPSDAGEYTAVVGQLEC 2827
Query: 332 STELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRI 391
+LFV + +TK +++ + ECEVS + W KNG EI K ++I
Sbjct: 2828 KAKLFVE--TLHITKTMKNIEVPETKTASFECEVSHFNVPSMWLKNGVEIEMSEK--FKI 2883
Query: 392 RVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEIC 451
V+GK H LII + D+AEY+ + Q SA L+V P+ I + L D +N ++
Sbjct: 2884 VVQGKLHQLIIMNTSTEDSAEYTFVCGNDQVSATLTV--TPIMITSMLKD--INAEEKDT 2939
Query: 452 LKCEISENIPG---KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPD-- 506
+ E++ N G KW KNG+ ++ +D+ ++ K H L I N D DY F
Sbjct: 2940 ITFEVTVNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKA 2999
Query: 507 AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAI 566
TL + I+ K I D + V+ + E +S EP W + D+
Sbjct: 3000 TSTATLYVEARHIEFRKHIKD-------IKVLEKKRAMFECEVS-EPDITVQWMKDDQE- 3050
Query: 567 MEGSGRIRTESYPDSSTLVIDIAERDDSGVYHI 599
++ + RI+ + L+I D+G Y +
Sbjct: 3051 LQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTV 3083
Score = 120 bits (301), Expect = 7e-27
Identities = 89/317 (28%), Positives = 143/317 (45%), Gaps = 11/317 (3%)
Query: 256 KILDPAYQVD--KGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINN 313
K++ P + V+ + RF E+++ + W G+ + + + +G L ++N
Sbjct: 5736 KLVRPLHSVEVMETETARFETEISEDDIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHN 5795
Query: 314 CQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVK 373
C++ A + K S L V+ I + + L+D T GE +CE+S +D V+
Sbjct: 5796 CRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCELSYEDIPVE 5855
Query: 374 WFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPL 433
W+ G+++ P K R EGK H L + DA E + ++ A L V P+
Sbjct: 5856 WYLKGKKLEPSDK--VVPRSEGKVHTLTLRDVKLEDAGEVQLTAKDFKTHANLFVKEPPV 5913
Query: 434 KILTPLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIAN 492
+ PL DQTV G L+CE+S EN KW KNG + +S + ++V GR+ KLVI +
Sbjct: 5914 EFTKPLEDQTVEEGATAVLECEVSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHD 5973
Query: 493 ALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGE 552
ED Y DA + ++V+ P L L + V R E +S E
Sbjct: 5974 CTPEDIKTYTC--DAKDFKTSCNLNVVPPHVEFLRPL---TDLQVREKEMARFECELSRE 6028
Query: 553 PPPKAMWSRGDKAIMEG 569
K W + I +G
Sbjct: 6029 -NAKVKWFKDGAEIKKG 6044
Score = 120 bits (301), Expect = 7e-27
Identities = 124/479 (25%), Positives = 201/479 (41%), Gaps = 76/479 (15%)
Query: 463 KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY--VFAPDAYNVTLPAKVHVID 520
KWTK G + S R + +LVI A D G Y V + KV VI
Sbjct: 23797 KWTKEGQDI--SKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIG 23854
Query: 521 PPKIILDGLDADNTVTVIAGNKLRLEIPISGEPP------------------PKAMWSRG 562
P L+ D+ + +S PP PKA W
Sbjct: 23855 SPNSPEGPLEYDDIQV--------RSVRVSWRPPADDGGADILGYILERREVPKAAWYTI 23906
Query: 563 DKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG-----EAHASIKVKV- 616
D R+R ++LV+ + + + ++ +N+ G ++ + K
Sbjct: 23907 DS-------RVR------GTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTP 23953
Query: 617 VDFPDPPV-APTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCK 675
++ P+PP P V +V ++W P DGGS + GY+IERK+ + +W+R N
Sbjct: 23954 LNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQIT 24013
Query: 676 ETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDT 732
T + ++ Y+ RI A N +G+S+ S S P V P S P L + S++
Sbjct: 24014 TTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKD 24073
Query: 733 TVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDK 792
+VT++W P+ G + GY +EY ++G++A W +NK+ I
Sbjct: 24074 SVTLQWEKPECDGGKEILGYWVEY-----------RQSGDSA-------WKKSNKERIKD 24115
Query: 793 TKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEII-EPPKIRIPRHLKQTYIR 851
+FTI GL + RV A N G S P+ + I K E P IR + +K
Sbjct: 24116 KQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIR--KEMKDV-TT 24172
Query: 852 RVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDT-IIFIRKAERSHSGKY 909
++GEA L G+P P++ W + G E+ +++ +S+ T + + E+ G Y
Sbjct: 24173 KLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVY 24231
Score = 118 bits (295), Expect = 4e-26
Identities = 143/575 (24%), Positives = 215/575 (37%), Gaps = 93/575 (16%)
Query: 597 YHINLKNEAGEAHASIKVKVVDF------PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSP 650
+ ++ +NE G S K V P PPV P + + + W+PP +DGGS
Sbjct: 10712 FRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSK 10771
Query: 651 ILGYFIERKKKQSSRWMRLNF--DLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMP 708
ILGY +E +K W R N + C ET ++ + +G Y+ R+ AVNA G S P+
Sbjct: 10772 ILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHV 10831
Query: 709 SRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSD 768
P + PP L + D + HI D L +G
Sbjct: 10832 PEPVLVKDRLEPPEL-----ILDANMARE----QHIKVG--DTLRLSAIIKG-------- 10872
Query: 769 ENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAG----ASEPKYY 824
P W ++D K + +T P +K+ +R A G E
Sbjct: 10873 ------VPFPKVTWKKEDRDAPTKARIDVT--PVGSKLEIRNAAHEDGGIYSLTVENPAG 10924
Query: 825 SQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKK---DGAEID 881
S+ + VK ++ K PR L+ + IR K LTWK+ DG +
Sbjct: 10925 SKTVSVKVLVLD-KPGPPRDLEVSEIR--------------KDSCYLTWKEPLDDGGSVI 10969
Query: 882 KNQINIRNSETD---TIIFIRKAERSHSGKY-------------DLQVKVDKFVETASID 925
N + R + + ++SH K+ + Q FVET
Sbjct: 10970 TNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPK-P 11028
Query: 926 IQIIDR---PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVI 982
I+ +D PGPP+ + DV V+L W P DG + ITGY ++ ++ + +W
Sbjct: 11029 IKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIK-F 11087
Query: 983 EHYHRTSATITELVIGNEYYFRVFSENMCGLS-EDATMTKESAVIARDGKIYKNPVYEDF 1041
+ +T L G Y FRV +EN+ GL D T+ E K+ V D
Sbjct: 11088 KTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLPDTTIPIEC-----QEKLVPPSVELDV 11142
Query: 1042 DFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGV 1101
E + AG +RG P P W + I D Y + ++
Sbjct: 11143 KLIEGLVVK---------AGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFS 11193
Query: 1102 CTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
L I+ D G Y N G+ + L V
Sbjct: 11194 SVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 11228
Score = 116 bits (290), Expect = 1e-25
Identities = 185/884 (20%), Positives = 323/884 (36%), Gaps = 156/884 (17%)
Query: 313 NCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDT-TAYCGERVELECEV-SEDDA 370
N DS +TA DE + P + + +D + GE LE ++ +
Sbjct: 18313 NFSEPSDSSGAITARDE-------IDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIP 18365
Query: 371 NVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEY--SVMTTGGQSSAKLSV 428
+V W K+G+E+ +R I+ +K L+++ + D +Y + GG S ++V
Sbjct: 18366 DVVWSKDGKEL-EETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITV 18424
Query: 429 DLK--------PLKIL------------TPLTDQTVNLGKEICLKCEISENIPGKWTKNG 468
+ PLK+ PL D N+ I K E S WT+
Sbjct: 18425 KVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRL---SWTQVS 18481
Query: 469 LPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF---APDAYNVTLPAKVHVID----- 520
VQ + ++ KL+ N +Y+F A + Y + P + +
Sbjct: 18482 TEVQALNY-------KVTKLLPGN-------EYIFRVMAVNKYGIGEPLESGPVTACNPY 18527
Query: 521 -----PPKIILDGLDADNTVTVIA------GNKLRLEIPISGEPPPKAMWSRGDKAIMEG 569
P + + D+ V A G ++ I + W++ +K +
Sbjct: 18528 KPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYI-LEKRDKEGVRWTKCNKKTLTD 18586
Query: 570 SGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGE-AHASIKVKVVDF---PDPPVA 625
R+R + + +A + +GV GE + S+ + D P PP
Sbjct: 18587 L-RLRVTGLTEGHSYEFRVAAENAAGV---------GEPSEPSVFYRACDALYPPGPPSN 18636
Query: 626 PTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETT------F 679
P VT+ + W P YDGG+P+ GY +E K+ + W C T F
Sbjct: 18637 PKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTT-----CTPPTGLQGKQF 18691
Query: 680 EPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTL-----------LTVDS 728
K+ E Y RI A+N+ G+ +P+ V PP + L +
Sbjct: 18692 TVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASA 18751
Query: 729 VTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKD 788
VT++ RP + +G + + TS+ ++ N
Sbjct: 18752 TLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTM--------------LVIDNVT 18797
Query: 789 LIDKTKFTIT--GLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLK 846
D ++ +T FV V+ +++ A P+ + I E K + +
Sbjct: 18798 RFDSGRYNLTLENNSGSKTAFVNVRVLDSPSA--------PVNLT-IREVKKDSVTLSWE 18848
Query: 847 QTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHS 906
I + N ++ + R + K I N + + R S
Sbjct: 18849 PPLIDGGAKITNYIVEKRETTRKAYATITNNCT--KTTFRIENLQEGCSYYFRVLA---S 18903
Query: 907 GKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGY 966
+Y + + + + +++ + P PP V + DV + W P+ DG + ITGY
Sbjct: 18904 NEYGIGLPAE-----TTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGY 18958
Query: 967 TIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVI 1026
++ K S +W T + ATI+ L G EY FRV + N G S+ + VI
Sbjct: 18959 VVEMQTKGSEKWSTCTQ-VKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVP--VI 19015
Query: 1027 ARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVA 1086
ARD +I P P A ++ +G P+ + W K+
Sbjct: 19016 ARDIEI-------------KPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQT 19062
Query: 1087 IVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEI 1130
+ + R + S++ V +L I++ S D GTY N G++ +
Sbjct: 19063 LKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITV 19106
Score = 115 bits (288), Expect = 2e-25
Identities = 180/802 (22%), Positives = 307/802 (38%), Gaps = 107/802 (13%)
Query: 373 KWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKP 432
KW +G EI Y + + +L I+ + D EY + + S ++V L
Sbjct: 11171 KWTTDGSEI--KTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 11228
Query: 433 LKILTPLTDQTVNLG---KEICLKCEISENIPGKWTKNGLPVQESDRLK----VVHKGRI 485
L + P T L + + + + ++ G N + V++ D K VV G
Sbjct: 11229 LDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYI-VEKQDTRKDTWGVVSSGSS 11287
Query: 486 H-KLVIANALTEDEGDYVFAPDAYNV---------TLPAKVHVIDPPKIILDGLDADNTV 535
KL I + + +YVF A N T H PP V
Sbjct: 11288 KTKLKIPHL--QKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSP-----PGKPVV 11340
Query: 536 TVIAGNKLRLE--IPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERD- 592
T I N + +P S P + + + R+ D V + E +
Sbjct: 11341 TDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVNKTPIADLKFRVTGLYEGNT 11400
Query: 593 -DSGVYHINLKNEAGEAHASIKVKV---VDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGG 648
+ V+ NL + + +S +K + P PP+ P + + + + W P DGG
Sbjct: 11401 YEFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGG 11460
Query: 649 SPILGYFIERKKKQSSRWMRLNFD-LCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSM 707
SPILGY +E +K +++W R+N D L ++ F +IEG Y RI A N +G +P
Sbjct: 11461 SPILGYVVECQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRE 11520
Query: 708 PSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAA--GLDGYVLEYCFEGSTSAK 765
+ + + PP + +D +T+R I A G + + EG +
Sbjct: 11521 LAESVIAKDILHPPEV-ELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVR 11579
Query: 766 QSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYS 825
+ + + DLP + + D K+ I+ A N++G ++
Sbjct: 11580 E--KRVDLIQDLPRVELQIKEAVRADHGKYIIS-------------AKNSSG------HA 11618
Query: 826 QPILVKEIIEPPKIRIPRHLKQTYIRRVG--------------EAVNLVIPFQGKPRPEL 871
Q + +++ P ++LK T + + E N ++ ++ KP +
Sbjct: 11619 QGSAIVNVLDRPGPC--QNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYR-KPNQK- 11674
Query: 872 TWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETAS--IDIQII 929
W +++ K I + F AE +V V +ET + + I I
Sbjct: 11675 GWSIVASDVTKRLIKANLLANNEYYFRVCAEN--------KVGVGPTIETKTPILAINPI 11726
Query: 930 DRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTS 989
DRPG P+ + I D V L W P DG + Y +++ K S +W V + + +
Sbjct: 11727 DRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKET 11786
Query: 990 ATITELVIGNEYY-FRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPM 1048
+ + + N+ Y FRV ++N G S+ + E V+ D + P+
Sbjct: 11787 HYMVDRCVENQIYEFRVQTKNEGGESD--WVKTEEVVVKED--------------LQKPV 11830
Query: 1049 FTQPLVNTYAI-AGYNATLNCSVRGNPKPKITWMKNKVA--IVDDPRYRMFSNQGVCTLE 1105
L + AG L VRG P P++ W K+K A + PR ++ +
Sbjct: 11831 LDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFS 11890
Query: 1106 IRKPSPYDGGTYCCKAVNDLGT 1127
+ K DGG Y A N G+
Sbjct: 11891 LTKAKRSDGGKYVVTATNTAGS 11912
Score = 115 bits (288), Expect = 2e-25
Identities = 190/873 (21%), Positives = 328/873 (37%), Gaps = 153/873 (17%)
Query: 324 VTAGDEKCSTELFVREPPIMVTKQLEDT-TAYCGERVELECEV-SEDDANVKWFKNGEEI 381
+TA DE V P I + + +DT + GE +++ ++ + ++W K +E+
Sbjct: 16160 ITARDE-------VDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQEL 16212
Query: 382 IPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTD 441
+R I+ L ++ A + D+ Y + ++V++K L P
Sbjct: 16213 --SNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEG 16270
Query: 442 QTVNLGKEICLKCEISENIPGKWTKNGLPVQE--SDRLKVVHKGR-----IHKLVIANAL 494
V G KC ++ W P+Q+ SD + + + R + +V AN
Sbjct: 16271 PVVISGVT-AEKCTLA------WKP---PLQDGGSDIINYIVERRETSRLVWTVVDANVQ 16320
Query: 495 TED-------EG-DYVF---APDAYNVTLPAKVH--VIDPPKIILDGLDADNTVTVIAGN 541
T EG +Y F A + Y V P + V P ++ D A TV +
Sbjct: 16321 TLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDS 16380
Query: 542 KLRL-EIPISG------------EPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDI 588
+ + E P S W+R K ++ G R+R V +
Sbjct: 16381 MIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLI-GELRLR----------VTGL 16429
Query: 589 AERDDSGVYHINLKNEAGEAHAS---IKVKVVD---FPDPPVAPTVTEVGDDWCIMNWEP 642
E D + ++ +N AG + S K D P PP P V ++ ++W
Sbjct: 16430 IENHDYE-FRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSK 16488
Query: 643 PAYDGGSPILGYFIERKKKQSSRWMRLNFDL-CKETTFEPKKMIEGVAYEVRIFAVNAIG 701
P YDGG I GY +E+ W +T E +K++E Y RI A+N G
Sbjct: 16489 PIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAG 16548
Query: 702 ISKPSMPSRPFVPLAVTSPPTL-----------LTVDSVTDTTVTMRWRPPDHIGAAGLD 750
+ + + P + P + + V ++ RP + +D
Sbjct: 16549 VGEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVD 16608
Query: 751 GYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTIT--GLPTDAKIFV 808
G + + TS+ S ++ N + D K+T+T FV
Sbjct: 16609 GEIRDAAIIDVTSSFTS--------------LVLDNVNRYDSGKYTLTLENSSGTKSAFV 16654
Query: 809 RVKAVNAAGASEPKYYSQPILVKEII----EPPKIRIPRHLKQTYIRRVGEAVNLVIPFQ 864
V+ ++ S P + K+ + EPP + +K + +
Sbjct: 16655 TVRVLDTP--SPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEK------------ 16700
Query: 865 GKPRPELTWKKDGAEID---KNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVET 921
E T K A + KN I + + R + G + +T
Sbjct: 16701 ----REATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYG-------IGLPAQT 16749
Query: 922 ASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV 981
A I++ + P PP + ++DV +V+L+WT P+ DG + I Y ++ K S +W +
Sbjct: 16750 AD-PIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKW-SE 16807
Query: 982 IEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDF 1041
A IT L G EY FRV + N G S+ ++ ++A+D I +
Sbjct: 16808 CARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVP--IVAKDLVIEPD------ 16859
Query: 1042 DFSEAPMFTQPLVNTYAI-AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQG 1100
+P ++Y++ G + + + G PKP ITW K+ + + R + +
Sbjct: 16860 --------VKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLD 16911
Query: 1101 VCTLEIRKPSPYDGGTYCCKAVNDLG--TVEIE 1131
+ TL I++ DGG Y N +G T IE
Sbjct: 16912 LTTLSIKETHKDDGGQYGITVANVVGQKTASIE 16944
Score = 115 bits (287), Expect = 3e-25
Identities = 101/370 (27%), Positives = 158/370 (42%), Gaps = 34/370 (9%)
Query: 266 KGGRVRFVVELAD-----------------PKLEVKWYKNGQEIRPSTKYIFEHKGCQRI 308
+G V FV EL D +E KWY N E++ + KY + ++
Sbjct: 2217 EGAVVEFVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQN 2276
Query: 309 LFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSED 368
L + + D EY +K + +L ++ PI + + L D G+ V+LE +VS +
Sbjct: 2277 LTVKDVTKEDQGEYSFVIDGKKTTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLE 2336
Query: 369 DANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSV 428
W K+G+E+ P R I ++ + H+L+IE TK DA YS S V
Sbjct: 2337 SVEGVWMKDGQEV--QPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRV 2394
Query: 429 DLKPLKILTPLTDQTVNLGKEICLKCEIS--ENIPGKWTKNGLPVQESDRLKVVHKGRIH 486
+ + ++TPL D V G + L+C++S + KW N ++ DR++ + KG
Sbjct: 2395 SVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQ 2454
Query: 487 KLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLE 546
+LVI DEG Y V I I+ GL D T T +E
Sbjct: 2455 RLVINRTHASDEGPYKLIVGRVETNCNLSVEKIK----IIRGL-RDLTCTETQNVVFEVE 2509
Query: 547 IPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG 606
+ SG +W+ DK I + S + + E++ L + +DD G Y AG
Sbjct: 2510 LSHSG---IDVLWNFKDKEI-KPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTF----YAG 2561
Query: 607 EAHASIKVKV 616
E S K+ V
Sbjct: 2562 ENMTSGKLTV 2571
Score = 110 bits (276), Expect = 6e-24
Identities = 178/830 (21%), Positives = 319/830 (38%), Gaps = 108/830 (13%)
Query: 352 TAYCGERVELECEVS-EDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADA 410
T G + L+ V + + + W K +E+ K ++ GK+ +I+ ++D+
Sbjct: 22686 TIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEK--VSLQYTGKRATAVIKFCDRSDS 22743
Query: 411 AEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIP-----GKWT 465
+Y++ + +SV +K L P TV+ + KC ++ ++P + T
Sbjct: 22744 GKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTVSRVTQE--KCTLAWSLPQEDGGAEIT 22801
Query: 466 KNGLPVQESDRLK-VVHKGRIHKLVIANALTEDEGDYVF---APDAYNVTLPAKVH---- 517
+ +E+ RL V+ +G L +Y+F A + Y +P +
Sbjct: 22802 HYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVA 22861
Query: 518 ----VIDPPKIILDGLDADNTVTVI--------AGNKLRLEIPISGEPPPKAMWSRGDKA 565
I P I + + +I GN++ + + W+R +K
Sbjct: 22862 RNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYL-VDKREKKSLRWTRVNKD 22920
Query: 566 IMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDF-PDPPV 624
+ R++ S + + + +G +E EA I + + P PP
Sbjct: 22921 YVVYDTRLKVTSLMEGCDYQFRVTAVNAAG------NSEPSEASNFISCREPSYTPGPPS 22974
Query: 625 APTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLC-KETTFEPKK 683
AP V + + W P YDGG+ I+GY +E ++K + +W R++ + + T F
Sbjct: 22975 APRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPD 23034
Query: 684 MIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDH 743
+ G Y R+ AVN G+S+ S P+ P L D + T VT+R
Sbjct: 23035 LKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKT-VTIRAGASLR 23093
Query: 744 --IGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLP 801
+ +G V+ + +G A ++ + +Y L IV + D K+TI
Sbjct: 23094 LMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSL----LIVDKVNRYDAGKYTI---- 23145
Query: 802 TDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEP---PKIRIPRHLKQTY-----IRRV 853
+A N +G S +LVK P P +++ + + I +
Sbjct: 23146 ---------EAENQSGKK-----SATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTI 23191
Query: 854 --GEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDL 911
G VN I + + +K + K I T+ + R + G
Sbjct: 23192 DGGAPVNNYI-VEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYG---- 23246
Query: 912 QVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKA 971
+ + ET+ + + + P P +++ DV V L W P DG + +TGY ++
Sbjct: 23247 ---IGEPCETSDA-VLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEAC 23302
Query: 972 DKKSMEWF-------TVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESA 1024
+ W TV+EH T+T L G +Y FR+ ++N G+SE +A
Sbjct: 23303 KAGTERWMKVVTLKPTVLEH------TVTSLNEGEQYLFRIRAQNEKGVSEPRETV--TA 23354
Query: 1025 VIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNK 1084
V +D ++ D S T P + AG L + G P P +W
Sbjct: 23355 VTVQDLRVLPT-----IDLS-----TMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAG 23404
Query: 1085 VAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKL 1134
+ + R + ++ V L IR+ + D G Y + N GT K+
Sbjct: 23405 SKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKV 23454
Score = 110 bits (275), Expect = 8e-24
Identities = 93/366 (25%), Positives = 162/366 (44%), Gaps = 18/366 (4%)
Query: 269 RVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGD 328
R F E+++P + V+W K+ QE++ + + + + L I + +M+D +Y V AG
Sbjct: 3028 RAMFECEVSEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGG 3087
Query: 329 EKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSR 388
+ +LFV + + ++ +R +E EV+EDD + W+K+G EI + R
Sbjct: 3088 NVSTAKLFVEGRDVRIRSIKKEVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQER 3147
Query: 389 YRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDL-KPLKILTPLTDQTVNLG 447
++ VE + H + I ++DA EY+ + +SS L V+ +P ++L L TV G
Sbjct: 3148 HKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSG 3207
Query: 448 KEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF-A 504
K IS K W K + + K +H G+ + L++ A ED Y A
Sbjct: 3208 KPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEA 3267
Query: 505 PDAYNVTLPAKVHVIDPPKIILDGLD-----------ADNTVTVIAGNKLRLEIPISGEP 553
+ Y V + ++ P+++ + +TVT G R + +SG
Sbjct: 3268 KNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVT-SEGQPARFQCRVSG-T 3325
Query: 554 PPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIK 613
K W DK I + S R + D+ L I A +D G Y N G+ ++
Sbjct: 3326 DLKVSWYSKDKKI-KPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTAN 3384
Query: 614 VKVVDF 619
+ + F
Sbjct: 3385 LSLEGF 3390
Score = 108 bits (270), Expect = 3e-23
Identities = 103/437 (23%), Positives = 169/437 (38%), Gaps = 53/437 (12%)
Query: 719 SPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLP 778
SP L D + +V + WRPP G A + GY+LE ++P
Sbjct: 23858 SPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILE------------------RREVP 23899
Query: 779 AEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPK 838
W + + T + GL + + RV A N G S+P +P+ K + PP+
Sbjct: 23900 KAAWYTIDSR-VRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPE 23958
Query: 839 IRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQIN----IRNSETD- 893
P + +V+L +P+ + + G I++ + + +R+++T
Sbjct: 23959 ---PPSNPPEVLDVTKSSVSLS---WSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQI 24012
Query: 894 TIIFIRKAERSHSGKYDLQVKVDKFV---ETASIDIQII-----DRPGPPQIVKIEDVWG 945
T +Y ++ V ET+ ++ D+P P ++I +
Sbjct: 24013 TTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISK 24072
Query: 946 ENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF-TVIEHYHRTSATITELVIGNEYYFR 1004
++V L W P+ DG I GY ++ W + E TI L+ EY FR
Sbjct: 24073 DSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFR 24132
Query: 1005 VFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNA 1064
VF+EN GLS G EAP + + + G A
Sbjct: 24133 VFAENETGLSRPRRTAMSIKTKLTSG--------------EAPGIRKEMKDVTTKLGEAA 24178
Query: 1065 TLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVND 1124
L+C + G P P I W + ++ +Y+M S+ TL + D G Y C A N+
Sbjct: 24179 QLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNE 24238
Query: 1125 LGTVEIECKLEVKVIAQ 1141
+G VE KL ++ Q
Sbjct: 24239 VGEVETSSKLLLQATPQ 24255
Score = 107 bits (268), Expect = 5e-23
Identities = 123/468 (26%), Positives = 198/468 (42%), Gaps = 56/468 (11%)
Query: 196 RREVKQQEEE---PQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSA 252
R + K++ EE + EL K YE++ + +L K + EEKK+
Sbjct: 1952 RSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRK----TKDELLHWTKELTEEEKKAL 2007
Query: 253 AF-AKILDPAYQVDK-----------------------GGRVRFVVELAD-PKLEVKWYK 287
A KI P ++ DK G F V + P E +WYK
Sbjct: 2008 AEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYK 2067
Query: 288 NGQEIRPSTK---YIFEHKGCQRILFINNCQMTDDSEYYV----TAGDEKCSTELFVREP 340
NG +I S + Y E C+ L I + D + V AG+ L V+
Sbjct: 2068 NGVKIERSDRIYWYWPEDNVCE--LVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAK 2125
Query: 341 PIMV-TKQLEDTTAYCGERV-ELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKH 398
++ T++L+D A + + ECE SE VKW+K+G E+ G K YR+ + K H
Sbjct: 2126 QLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGDK--YRMHSDRKVH 2183
Query: 399 ILIIEGATKADAAEYS---VMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCE 455
L I +DA +YS V +++AKL V+ ++ + L D V L+C
Sbjct: 2184 FLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGELECI 2243
Query: 456 IS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPA 514
+S ENI GKW N + ++ + + + + L + + ED+G+Y F D T
Sbjct: 2244 VSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTT--C 2301
Query: 515 KVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIR 574
K+ + P IL GL V G+ ++LE+ +S E + +W + D ++ S R+
Sbjct: 2302 KLKMKPRPIAILQGLSDQK---VCEGDIVQLEVKVSLE-SVEGVWMK-DGQEVQPSDRVH 2356
Query: 575 TESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDP 622
S L+I+ ++D+G Y + + V VD P
Sbjct: 2357 IVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDVITP 2404
Score = 107 bits (266), Expect = 8e-23
Identities = 171/808 (21%), Positives = 305/808 (37%), Gaps = 106/808 (13%)
Query: 356 GERVELECEVSEDDA-NVKWFKNGEEIIPGPKSRYRIRVEGKKHI--LIIEGATKADAAE 412
G V+L +S A ++W+K+ +E+ ++ + VE + ++I+ A + ++
Sbjct: 20515 GTSVKLRAGISGKPAPTIEWYKDDKEL----QTNALVCVENTTDLASILIKDADRLNSGC 20570
Query: 413 YSVMTTGGQSSAKLSVDL----KPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNG 468
Y + SA ++ + KP P+ +TV K L +++ K T
Sbjct: 20571 YELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYI 20630
Query: 469 LPVQESDRLK-VVHKGRIHKLVIANALTEDEGDYVF---APDAYNVTLPAKVH-VIDPPK 523
+ +E+ R+ + + + +I +Y+F A + Y + P + V+
Sbjct: 20631 VEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNA 20690
Query: 524 IILDGLDADNTVTVIAGNKLRL----EIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYP 579
+ G VT I N + + I G + DK + G ++ E+
Sbjct: 20691 FVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSL-GWFKVLKETIR 20749
Query: 580 DSSTLVIDIAERDDSGVYHINLKNEAGE---AHASIKVKVVDFPDPPVAPTVTEVGDDW- 635
D+ V + E D Y + N AG+ + S K D DPP P + D
Sbjct: 20750 DTRQKVTGLTENSDYQ-YRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTK 20808
Query: 636 --CIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNF-DLCKETTFEPKKMIEGVAYEV 692
+ W P YDGGS + GY +E ++ + W ++ + T + + GV Y
Sbjct: 20809 SSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYF 20868
Query: 693 RIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGY 752
R+ AVN G +P + P + P + D V +R I AG D
Sbjct: 20869 RVSAVNCAGQGEPIEMNEPVQAKDILEAPEI-------DLDVALR---TSVIAKAGEDVQ 20918
Query: 753 VLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKA 812
VL F+G P W K+L +++I TD+ + +
Sbjct: 20919 VL-IPFKGRPP--------------PTVTWRKDEKNLGSDARYSIEN--TDSSSLLTIPQ 20961
Query: 813 VN-----------AAGASEPKYYSQPILVKEIIEP---PKIRIPRHLKQTYIRRVGE--- 855
V G EPK S + VK + P K+++ +H+ + + + +
Sbjct: 20962 VTRNDTGKYILTIENGVGEPK--SSTVSVKVLDTPAACQKLQV-KHVSRGTVTLLWDPPL 21018
Query: 856 ------AVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKY 909
+N VI + + + TW + + + T F R + G
Sbjct: 21019 IDGGSPIINYVI--EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIG-- 21074
Query: 910 DLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQ 969
+ + ET ++ + P P + + ++D +V L+WT P DG + IT Y ++
Sbjct: 21075 -----IGEPCETTE-PVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVE 21128
Query: 970 KADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARD 1029
+ K W + +++L + FRVF++N GLS+ T+
Sbjct: 21129 RKGKGEQTW-SHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTI---------- 21177
Query: 1030 GKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVD 1089
G I V E E + P G+N L +G PKP I+W+K+ + + +
Sbjct: 21178 GPI---TVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKE 21234
Query: 1090 DPRYRMFSNQGVCTLEIRKPSPYDGGTY 1117
R + TL I+ GG Y
Sbjct: 21235 SEFVRFSKTENKITLSIKNAKKEHGGKY 21262
Score = 106 bits (265), Expect = 1e-22
Identities = 117/456 (25%), Positives = 185/456 (40%), Gaps = 83/456 (18%)
Query: 597 YHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFI 656
Y +N + + AS + + D P P VT+V + W PAYDGGS ++GY I
Sbjct: 22544 YALNAAGVSKASEASRPIMAQNPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYII 22603
Query: 657 ERK---KKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIG-ISKPSMPSRPF 712
ERK + RW++ N+ + + F + EG YE R+ A NA G ISK S + P
Sbjct: 22604 ERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPV 22663
Query: 713 VPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGE 772
+PP + VT+R AG D VL+ G K G+
Sbjct: 22664 TCRDEYAPPKAELDARLHGDLVTIR---------AGSD-LVLDAAVGGKPEPKIIWTKGD 22713
Query: 773 AAYDL----------PAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPK 822
DL ++ D D K+T+T NA+G
Sbjct: 22714 KELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLT-------------VKNASGTK--- 22757
Query: 823 YYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTW----KKDGA 878
+ ++VK + P G L + + + L W + GA
Sbjct: 22758 --AVSVMVKVLDSP-----------------GPCGKLTVSRVTQEKCTLAWSLPQEDGGA 22798
Query: 879 EI--------DKNQIN--IRNSETDTIIFIRKAERSHSGKYDLQVK-VDKFVETASIDIQ 927
EI + +++N I E T+ ++ + +Y +V+ V+K+ ++ +
Sbjct: 22799 EITHYIVERRETSRLNWVIVEGECPTLSYV-VTRLIKNNEYIFRVRAVNKYGPGVPVESE 22857
Query: 928 -IIDR-----PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV 981
I+ R P PP I + E++ + WT P+ DG I+ Y + K +KKS+ W V
Sbjct: 22858 PIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRV 22917
Query: 982 IEHY--HRTSATITELVIGNEYYFRVFSENMCGLSE 1015
+ Y + T +T L+ G +Y FRV + N G SE
Sbjct: 22918 NKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSE 22953
Score = 106 bits (264), Expect = 1e-22
Identities = 128/545 (23%), Positives = 211/545 (38%), Gaps = 64/545 (11%)
Query: 620 PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTF 679
P PP P V + + W+PPA DGGSPI GY +E +++ ++ W R+N TT
Sbjct: 9333 PGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTC 9392
Query: 680 E--PKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMR 737
E + E Y R+ AVN G S+PS + + P + +D + +
Sbjct: 9393 ECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVF-IDIGAQDCLVCK 9451
Query: 738 WRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTI 797
I A + +E AK++ ++G +D+P + A + + + I
Sbjct: 9452 AGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDG--VHDIPED----AQLETAENSSVII 9505
Query: 798 TGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAV 857
+P + ++ A + K + + V ++ PPK LK + I R +
Sbjct: 9506 --IPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPK-----DLKVSDITRGSCRL 9558
Query: 858 NLVIP------------FQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIR-KAERS 904
+ +P + + W K + + + ++ F R +AE
Sbjct: 9559 SWKMPDDDGGDRIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAEN- 9617
Query: 905 HSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAIT 964
++ + V+ T + D I P PP +KI + V L+W PPK+DG + +T
Sbjct: 9618 ---RFGIGPPVETIQRTTARDP--IYPPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVT 9672
Query: 965 GYTIQ-----KADKKSMEWFTVIEH-YHRTSATITELVIGNEYYFRVFSENMCGLSEDAT 1018
Y ++ K W + T+ +LV G EY FRV + N G+S+ +
Sbjct: 9673 HYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPSA 9732
Query: 1019 MTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKI 1078
D P + +F E G N + ++G P P +
Sbjct: 9733 TVGPCDCQRPD----MPPSIDLKEFMEVE------------EGTNVNIVAKIKGVPFPTL 9776
Query: 1079 TWMK-------NKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIE 1131
TW K NK ++ D CTL I + D G Y AVN+LGT E
Sbjct: 9777 TWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKE 9836
Query: 1132 CKLEV 1136
+L V
Sbjct: 9837 MRLNV 9841
Score = 105 bits (263), Expect = 2e-22
Identities = 101/375 (26%), Positives = 158/375 (42%), Gaps = 21/375 (5%)
Query: 263 QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 322
+V +G V+ V+++ +E W K+GQE++PS + +L I + D Y
Sbjct: 2320 KVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNY 2379
Query: 323 YVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDD-ANVKWFKNGEEI 381
T ST V + V L+D G + LEC+VS D +VKW+ N E+I
Sbjct: 2380 SFTIPALGLSTSGRVSVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQI 2439
Query: 382 IPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTD 441
P R + V+G K L+I +D Y ++ +++ LSV+ +KI+ L D
Sbjct: 2440 --KPDDRVQAIVKGTKQRLVINRTHASDEGPYKLIVGRVETNCNLSVE--KIKIIRGLRD 2495
Query: 442 QTVNLGKEICLKCEISEN-IPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGD 500
T + + + E+S + I W ++ S + K+ G+I+KL + N + +DEG
Sbjct: 2496 LTCTETQNVVFEVELSHSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGK 2555
Query: 501 YVF--APDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAM 558
Y F + + L I P D TV E+ P K
Sbjct: 2556 YTFYAGENMTSGKLTVAGGAISKPL-------TDQTVAESQEAVFECEV---ANPDSKGE 2605
Query: 559 WSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVD 618
W R K + + IR+ES L+I + DD G Y K + A +KV+ V
Sbjct: 2606 WLRDGKH-LPLTNNIRSESDGHKRRLIIAATKLDDIGEY--TYKVATSKTSAKLKVEAVK 2662
Query: 619 FPDPPVAPTVTEVGD 633
TVTE D
Sbjct: 2663 IKKTLKNLTVTETQD 2677
Score = 103 bits (258), Expect = 7e-22
Identities = 110/456 (24%), Positives = 174/456 (38%), Gaps = 80/456 (17%)
Query: 702 ISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGS 761
+ KP +P+ P + D VT +T++W PP G + + Y+LE
Sbjct: 13701 VGKPGIPTGP------------IKFDEVTAEAMTLKWAPPKDDGGSEITNYILE------ 13742
Query: 762 TSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGA--- 818
K+ N + W+ + KT F +T L + RV A N G
Sbjct: 13743 ---KRDSVNNK---------WVTC-ASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEG 13789
Query: 819 --SEPKYYSQPILVKEIIEPPKIRIPRH----LKQTYIRRVGEAVNLVIPFQGKPRPELT 872
SEP P V + PP I RH L T ++ G + + K R L
Sbjct: 13790 LKSEPIVARHPFDVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLL 13849
Query: 873 WKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETAS--------I 924
WK+ +K I +R+ + + + +Y+ +V +
Sbjct: 13850 WKR----ANKTPIRMRDFKVTGL--------TEGLEYEFRVMAINLAGVGKPSLPSEPVV 13897
Query: 925 DIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIE- 983
+ ID PG P+++ I +V L WT PK DG +TGY ++K D S W
Sbjct: 13898 ALDPIDPPGKPEVINITR---NSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHV 13954
Query: 984 HYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDF 1043
+ + T+T+LV G +Y FR+ ++N G + + E+ +I +D ++
Sbjct: 13955 NVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTET-IICKD------------EY 14001
Query: 1044 SEAPMFTQPLVNTYAI--AGYNATLNC-SVRGNPKPKITWMKNKVAIVDDPRYRMFSNQG 1100
+ P + AG LN S+ G P PK +W K I ++ S
Sbjct: 14002 EAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPT 14061
Query: 1101 VCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
L I+ + D G Y A N GT K+ V
Sbjct: 14062 SSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTV 14097
Score = 102 bits (255), Expect = 2e-21
Identities = 103/389 (26%), Positives = 171/389 (43%), Gaps = 15/389 (3%)
Query: 248 EKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHK-GCQ 306
E+ F K L+ V KG + EL + + +V W K+G+ + I G
Sbjct: 4836 EELPVRFVKTLEEEVTVVKGQPLYLSCEL-NKERDVVWRKDGKIVVEKPGRIVPGVIGLM 4894
Query: 307 RILFINNCQMTDDSEYYVT---AGDEKCSTELFVREP-PIMVTKQLEDTTAYCGERVELE 362
R L IN+ TD Y VT A + +CS+ + V E + K + D
Sbjct: 4895 RALTINDADDTDAGTYTVTVENANNLECSSCVKVVEVIRDWLVKPIRDQHVKPKGTAIFA 4954
Query: 363 CEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQS 422
C++++D N+KWFK +EI P + I +G L I+ A D AEY+V G +
Sbjct: 4955 CDIAKDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGKRY 5014
Query: 423 SAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVH 481
AKL++ + +++L P+ D T+ + EISE +IPG+W G ++ S ++
Sbjct: 5015 PAKLTLGEREVELLKPIEDVTIYEKESASFDAEISEADIPGQWKLKGELLRPSPTCEIKA 5074
Query: 482 KGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGN 541
+G L + + G+ ++ A N A ++ +I LD VTV
Sbjct: 5075 EGGKRFLTLHKVKLDQAGEVLY--QALNAITTA---ILTVKEIELDFAVPLKDVTVPERR 5129
Query: 542 KLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINL 601
+ R E ++ E +WS+G I++ S + + LVI+ ++ DD GVY +
Sbjct: 5130 QARFECVLTRE--ANVIWSKGPD-IIKSSDKFDIIADGKKHILVINDSQFDDEGVYTAEV 5186
Query: 602 KNEAGEAHASIKVKVVDFPDPPVAPTVTE 630
+ + A + + F P TV E
Sbjct: 5187 EGKKTSARLFVTGIRLKFMSPLEDQTVKE 5215
Score = 102 bits (254), Expect = 2e-21
Identities = 85/281 (30%), Positives = 121/281 (43%), Gaps = 16/281 (5%)
Query: 283 VKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPI 342
V W K I+ S K+ G + IL IN+ Q D+ Y +K S LFV +
Sbjct: 5143 VIWSKGPDIIKSSDKFDIIADGKKHILVINDSQFDDEGVYTAEVEGKKTSARLFVTGIRL 5202
Query: 343 MVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILII 402
LED T GE CE+S + +V WFKN ++ I EGK H L +
Sbjct: 5203 KFMSPLEDQTVKEGETATFVCELSHEKMHVVWFKNDAKL--HTSRTVLISSEGKTHKLEM 5260
Query: 403 EGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPG 462
+ T D ++ S+A+L V L D+T EI LKCE+S+++P
Sbjct: 5261 KEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSKDVPV 5320
Query: 463 KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV----FAPDAYNVTLPAKVHV 518
KW K+G + S + + G L I A +D+G+YV NVT+ A++
Sbjct: 5321 KWFKDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIK 5380
Query: 519 IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMW 559
++ P L G V V G EI +S EP W
Sbjct: 5381 VEKP---LYG------VEVFVGETAHFEIELS-EPDVHGQW 5411
Score = 102 bits (254), Expect = 2e-21
Identities = 179/762 (23%), Positives = 289/762 (37%), Gaps = 135/762 (17%)
Query: 340 PPIMVTKQLEDTTAYCGERVELECEV-SEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKH 398
P I++ +Q+ T G+++ +E V + KW K +E++ S +
Sbjct: 12528 PKILMPEQI---TIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTS--SHLAVHKADSSS 12582
Query: 399 ILIIEGATKADAAEYSVMT--TGGQSSAKLSV--------------------DLKPLKIL 436
ILII+ T+ D+ YS+ + G + K+ V D L
Sbjct: 12583 ILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWH 12642
Query: 437 TPLTDQTVNLGKEICLKCEISENIPGKW-TKNGLPVQESDRLKVVHKGRIH--------K 487
PL D N+ I KC++S G W T + S R+ + G+ + +
Sbjct: 12643 IPLEDGGSNITNYIVEKCDVSR---GDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENR 12699
Query: 488 LVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIIL--DGLDADNTVTVIAGNKLRL 545
I+ LT + F + A+V ++ I + D D+D +I
Sbjct: 12700 FGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIG------ 12753
Query: 546 EIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEA 605
I + +W + + + +R+ YP + +++ E + I N+A
Sbjct: 12754 -YLIERKERNSLLWVKANDTL------VRSTEYPCAG--LVEGLEYS----FRIYALNKA 12800
Query: 606 GEAHASIKVKVVDFP---DPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQ 662
G + S + V DPP P V +V + W P +DGGS I+GYF+E K
Sbjct: 12801 GSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLP 12860
Query: 663 SSRWMRLNF--DLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSP 720
+W+R N + + + E Y+ R A A+ IS PS PS P LA P
Sbjct: 12861 GDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVP 12920
Query: 721 P---------TLLTVDSVT----DTTV------TMRWRPPDHIGAAGLDGYVLEYCFEGS 761
P +LLTV + T D TV T+ W+ DG +L+ EG
Sbjct: 12921 PRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKK---------DGTLLKPA-EGI 12970
Query: 762 TSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEP 821
A Q + E + V KD D T T +++K ++ G
Sbjct: 12971 KMAMQRNL-------CTLELFSVNRKDSGDYT-ITAENSSGSKSATIKLKVLDKPGPPAS 13022
Query: 822 ----KYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVG-EAVNLVIPFQGKPRPELTWKKD 876
K YS ++ EPP + G E N ++ + RP W +
Sbjct: 13023 VKINKMYSDRAMLSW--EPP------------LEDGGSEITNYIVDKRETSRPN--WAQV 13066
Query: 877 GAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ 936
A + ++ R + G D F E A I D PG
Sbjct: 13067 SATVPITSCSVEKLIEGHEYQFRICAENKYGVGD-----PVFTEPA-IAKNPYDPPGRCD 13120
Query: 937 IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATI--TE 994
I ++ +++ ++W PP DDG + ITGY ++K + +++ W T + T+ T
Sbjct: 13121 PPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNW-TKVNRKPIIERTLKATG 13179
Query: 995 LVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNP 1036
L G EY FRV + N G + + +K A ARD + P
Sbjct: 13180 LQEGTEYEFRVTAINKAGPGKPSDASK--AAYARDPQYPPGP 13219
Score = 98.6 bits (244), Expect = 3e-20
Identities = 93/361 (25%), Positives = 149/361 (41%), Gaps = 12/361 (3%)
Query: 271 RFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEK 330
+F E++ +W K QEI ++ G + + I + D+++Y A D+
Sbjct: 5486 KFECEVSREPKTFRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKH 5545
Query: 331 CSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYR 390
S +L + + L+D TA E E+S D+ VKWFKN + +
Sbjct: 5546 TSGKLIIEGIRLKFLTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRL--HTTRSVS 5603
Query: 391 IRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEI 450
++ EGK H + + + D ++ V G S AKL+V L D T E+
Sbjct: 5604 MQDEGKTHSITFKDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEV 5663
Query: 451 CLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYN 509
L+CEIS+ + P KW K+G ++ S + G+ L++ AL D G Y D
Sbjct: 5664 ILQCEISKADAPVKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTC--DCGT 5721
Query: 510 VTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWS-RGDKAIME 568
K+ + D ++ L ++V V+ R E IS E A W +G+ +
Sbjct: 5722 DKTSGKLDIEDREIKLVRPL---HSVEVMETETARFETEIS-EDDIHANWKLKGEALLQT 5777
Query: 569 GSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTV 628
I+ E S LV+ D +G N AH +K +V+ P TV
Sbjct: 5778 PDCEIKEEGKIHS--LVLHNCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTV 5835
Query: 629 T 629
T
Sbjct: 5836 T 5836
Score = 97.1 bits (240), Expect = 9e-20
Identities = 126/568 (22%), Positives = 206/568 (36%), Gaps = 75/568 (13%)
Query: 597 YHINLKNEAGEAHASIKVKVV---DFPDPPVAPTVTEVGDDW---CIMNWEPPAYDGGSP 650
+ + +NE G S+ + V D +PP PT V D + W P YDGG+P
Sbjct: 12096 FRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAP 12155
Query: 651 ILGYFIERKKKQSSR-----WMRLNFDL-CKETTFEPKKMIEGVAYEVRIFAVNAIGISK 704
I+GY +E + K + W R N F + E YE R+ A N +GI +
Sbjct: 12156 IIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGR 12215
Query: 705 PSMPSRPFVPLAVTSPPTLLTVDSVTDTTVT-----------MRWRPPDHIG--AAGLDG 751
P+ P + PP + S+ + +R RP + G+D
Sbjct: 12216 PAELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDN 12275
Query: 752 YVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGL-PTDAK-IFVR 809
V + Q D A+ ++ N D K+++T + P K +FV
Sbjct: 12276 VVRK---------GQVDLVDTMAF------LVIPNSTRDDSGKYSLTLVNPAGEKAVFVN 12320
Query: 810 VKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRP 869
V+ ++ G P+ ++ + K H+ G + + +
Sbjct: 12321 VRVLDTPG---------PVSDLKVSDVTKTSC--HVSWAPPENDGGSQVTHYIVEKREAD 12369
Query: 870 ELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQII 929
TW E+ K ++ N + R + G V V + +
Sbjct: 12370 RKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGP-----GVPTDVPKPVLASDPL 12424
Query: 930 DRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGY-TIQKADKKSMEWFTVIEHYHRT 988
P PP+ +++ ++ + L W PP DG A I GY T + +++ + +T
Sbjct: 12425 SEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDL 12484
Query: 989 SATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPM 1048
S +T L G +Y FRV + N G+S + R+ + VYE + P
Sbjct: 12485 SLVVTGLKEGKKYKFRVAARNAVGVS-----------LPREAE----GVYEAKEQLLPPK 12529
Query: 1049 FTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRK 1108
P T AG + V G P P W K + +V + L I+
Sbjct: 12530 ILMPEQITIK-AGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKD 12588
Query: 1109 PSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
+ D G Y A N GT + K+ V
Sbjct: 12589 VTRKDSGYYSLTAENSSGTDTQKIKVVV 12616
Score = 94.4 bits (233), Expect = 6e-19
Identities = 147/655 (22%), Positives = 260/655 (39%), Gaps = 108/655 (16%)
Query: 20 EEPSKEKEAGTTPAKDWTLVETPPGEEQAKQNANSQLSILFIEKPQGGTVKVGEDITFIA 79
E+ SK E + K T E +A + +S+ I + Q TV F
Sbjct: 26444 EKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVI--VTGLQDTTVSSDSVAKFAV 26501
Query: 80 KVKAEDLLRKPTIKWFK--------GKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIK 131
K E +PT W K GK+ K G L++ +T S +YT ++
Sbjct: 26502 KATGEP---RPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVK--- 26555
Query: 132 AKDNFAGNYR--CEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSGEGQEDAGELD 189
N AG+ C++T K D+ + + +++ TP K++ +E + +
Sbjct: 26556 ---NSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQ-------KKAVVQEEISQKAL 26605
Query: 190 FSGLLKRREVKQQE------EEPQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKRLKR 243
S +K E K QE E +V + E +K + + EK IT
Sbjct: 26606 RSEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKTS-------- 26657
Query: 244 MRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHK 303
EE ++ A K +++G R+ +A +VKW NG E+ S +Y +
Sbjct: 26658 QASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGAT-DVKWVLNGVELTNSEEYRYGVS 26716
Query: 304 GCQRILFINNCQMTDDSEYYVTA----GDEKCSTELFVREPPIMVTKQLEDTTAYC---- 355
G + L I D+ + G KC +L ++K+L D A+
Sbjct: 26717 GSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDL-------TLSKELSDAPAFISQPR 26769
Query: 356 ------GERVELECEVS-EDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKA 408
G+ V CE+S E ++WFKN I S I + L I A+ +
Sbjct: 26770 SQNINEGQNVLFTCEISGEPSPEIEWFKNNLPI--SISSNVSISRSRNVYSLEIRNASVS 26827
Query: 409 DAAEYSVMTTG--GQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTK 466
D+ +Y++ GQ SA S+ ++ PL ++ +E+ L+ ++ G ++
Sbjct: 26828 DSGKYTIKAKNFRGQCSATASL------MVLPLVEEP---SREVVLRTSGDTSLQGSFSS 26878
Query: 467 NGLPVQESDR-----------LKVVHKGRIHKLVIANALTEDEGDYVFAPDAY----NVT 511
+ + S + + + + + + + E + ++ N+T
Sbjct: 26879 QSVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMT 26938
Query: 512 ---------LPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRG 562
L A + I PPKI + L +D +++ G L + +GEP P+ WS G
Sbjct: 26939 QLESSTSKMLKAGIRGI-PPKI--EALPSD--ISIDEGKVLTVACAFTGEPTPEVTWSCG 26993
Query: 563 DKAI-MEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKV 616
+ I + GR E+ D +TL+I ++ D G+Y ++L NE G A++ + +
Sbjct: 26994 GRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 27048
Score = 94.0 bits (232), Expect = 7e-19
Identities = 93/416 (22%), Positives = 158/416 (37%), Gaps = 58/416 (13%)
Query: 728 SVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANK 787
+VT +T+ WRPP G A + Y++E E + + +E
Sbjct: 20605 TVTAEKITLLWRPPADDGGAKITHYIVE-----------KRETSRVVWSMVSEH------ 20647
Query: 788 DLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQ 847
+++ T T + + RV+AVN G EP + + P IP K
Sbjct: 20648 --LEECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKI 20705
Query: 848 T-------YIRRVGEAVNLVIPF--QGKPRPELTW---KKDGAEIDKNQINIRNSETDTI 895
T + R + + + + + + + + L W K+ + ++ +D
Sbjct: 20706 TKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQ 20765
Query: 896 IFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPP 955
+ + G + + +F + A ID PGPP ++I D ++ L W+ P
Sbjct: 20766 YRVCAVNAAGQGPFS---EPSEFYKAADP----IDPPGPPAKIRIADSTKSSITLGWSKP 20818
Query: 956 KDDGNAAITGYTIQKADKKSMEWFTVIE--HYHRTSATITELVIGNEYYFRVFSENMCGL 1013
DG +A+TGY ++ + EW TV T ++ L G YYFRV + N G
Sbjct: 20819 VYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQ 20878
Query: 1014 SEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLV---NTYAIAGYNATLNCSV 1070
E M N + D EAP + + A AG + +
Sbjct: 20879 GEPIEM---------------NEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPF 20923
Query: 1071 RGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLG 1126
+G P P +TW K++ + D RY + + L I + + D G Y N +G
Sbjct: 20924 KGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVG 20979
Score = 92.0 bits (227), Expect = 3e-18
Identities = 69/216 (31%), Positives = 100/216 (46%), Gaps = 18/216 (8%)
Query: 930 DRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV-IEHYHRT 988
++PG P I V ++ + W PP DG A I Y ++K +KK +W +V E T
Sbjct: 24451 EKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRET 24510
Query: 989 SATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFS-EAP 1047
++ L+ G EY FRV EN+ G SE + +++ P+ D +AP
Sbjct: 24511 VFSVKNLIEGLEYEFRVKCENLGGESEWSEISE--------------PITPKSDVPIQAP 24556
Query: 1048 MFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMK-NKVAIVDDPRYRMFS-NQGVCTLE 1105
F + L N NATL C V G+PKP + W + K I D +YR+ G L
Sbjct: 24557 HFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLI 24616
Query: 1106 IRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVIAQ 1141
I + D Y +A N G+V LEV+V A+
Sbjct: 24617 IASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAK 24652
Score = 89.4 bits (220), Expect = 2e-17
Identities = 99/438 (22%), Positives = 170/438 (38%), Gaps = 59/438 (13%)
Query: 600 NLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERK 659
N+ ++ + S + +D DPP P + + W P Y GG I Y +E++
Sbjct: 14965 NMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKR 15024
Query: 660 KKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIG-ISKPSMPSRPFVPLAVT 718
+ RW++ NF E F + E AYE R+ A NA G IS PS PS
Sbjct: 15025 DLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDV 15084
Query: 719 SPPTLLTVDSVTDTTVTMRWRPPDHIGA--AGLDGYVLEYCFEGSTSAKQSDENGEAAYD 776
P + VD TV ++ + A +G +E+ +G + G A +
Sbjct: 15085 EAPK-IKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDG------KELEGTAKLE 15137
Query: 777 LPAEDWI--VANKDLI--DKTKFTITGLPTD--AKIFVRVKAVNAAGASEPKYYSQPILV 830
+ D+ + NKD D +T+T AK VK ++ G E P+ V
Sbjct: 15138 IKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPE-----GPLAV 15192
Query: 831 KEIIE--------PPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDK 882
E+ PP + G ++ I Q + L W +E+
Sbjct: 15193 TEVTSEKCVLSWFPP------------LDDGGAKIDHYI-VQKRETSRLAWTNVASEVQV 15239
Query: 883 NQINI-RNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIE 941
++ + + + + IF A + L+ + + P PP+ ++
Sbjct: 15240 TKLKVTKLLKGNEYIFRVMAVNKYGVGEPLE-------SEPVLAVNPYGPPDPPKNPEVT 15292
Query: 942 DVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF-----TVIEHYHRTSATITELV 996
+ +++ + W P DG + I Y +++ DK W T+ + ++ S L
Sbjct: 15293 TITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSG----LT 15348
Query: 997 IGNEYYFRVFSENMCGLS 1014
G+EY FR+ +EN G+S
Sbjct: 15349 EGHEYEFRIMAENAAGIS 15366
Score = 89.0 bits (219), Expect = 2e-17
Identities = 61/198 (30%), Positives = 88/198 (44%), Gaps = 18/198 (9%)
Query: 932 PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSAT 991
P PP+ VK D ++ LTW PPK+DG + I GY +++ + S +W E T
Sbjct: 7216 PDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPVAETKME 7275
Query: 992 ITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAP---M 1048
+T L G Y +RV + N G S+ + T+E + D EAP +
Sbjct: 7276 VTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAV---------------DTQEAPEIFL 7320
Query: 1049 FTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRK 1108
+ L AG L +V G P+PKITW K + + D R + + T+ I
Sbjct: 7321 DVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVD 7380
Query: 1109 PSPYDGGTYCCKAVNDLG 1126
D GTY +AVN G
Sbjct: 7381 SKRSDTGTYIIEAVNVCG 7398
Score = 86.7 bits (213), Expect = 1e-16
Identities = 112/510 (21%), Positives = 197/510 (38%), Gaps = 70/510 (13%)
Query: 648 GSPILGYFIERKKKQSSRWMRLNFDLCKET-TFEPKKMIEGVAYEVRIFAVNAIGISKPS 706
G P+ + R MR N ++ E T K+ + A I A N+ G +K
Sbjct: 20130 GKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAF 20189
Query: 707 MPSRPFVPLAVTSPPT-LLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAK 765
+ V L PPT + + +T+ +VT++W PP + G + + Y+L + TS
Sbjct: 20190 IN---IVVLDRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYIL---LKRETSTA 20243
Query: 766 QSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYS 825
E + +T + L T + R+KA N G S+ S
Sbjct: 20244 VWTEVSAT----------------VARTMMKVMKLTTGEEYQFRIKAENRFGISD-HIDS 20286
Query: 826 QPILVK---EIIEPPKIRIPRHLKQTYI-----RRVGEAVNLVIPF--QGKPRPELTWKK 875
+ VK PP ++ + I V + V+ + + K R + W+K
Sbjct: 20287 ACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQK 20346
Query: 876 DGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETA-----SIDIQIID 930
N++ IR + + S Y+ +V + S + ID
Sbjct: 20347 ------ANKLVIRTTH------FKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAID 20394
Query: 931 RPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV-IEHYHRTS 989
PP+ V+I D+ +V+L+W P DG + ITGY +++ D W + T
Sbjct: 20395 ACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVTETQ 20454
Query: 990 ATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMF 1049
I+ L ++Y FRVF+ N G +++ S V+ P+ D P+
Sbjct: 20455 FIISGLTQNSQYEFRVFARNAVG-----SISNPSEVVG--------PI-TCIDSYGGPVI 20500
Query: 1050 TQPLVNTYAI---AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEI 1106
PL T + AG + L + G P P I W K+ + + + + + ++ I
Sbjct: 20501 DLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILI 20560
Query: 1107 RKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
+ + G Y K N +G+ ++++
Sbjct: 20561 KDADRLNSGCYELKLRNAMGSASATIRVQI 20590
Score = 86.3 bits (212), Expect = 2e-16
Identities = 94/359 (26%), Positives = 158/359 (44%), Gaps = 23/359 (6%)
Query: 285 WYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVT---AGDEKCST-ELFVREP 340
W K+G IR S K+ F G R L I + Q++D EY EK ST +L V E
Sbjct: 4779 WMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEEL 4838
Query: 341 PIMVTKQL-EDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHI 399
P+ K L E+ T G+ + L CE+++ + +V W K+G+ ++ P R V G
Sbjct: 4839 PVRFVKTLEEEVTVVKGQPLYLSCELNK-ERDVVWRKDGKIVVEKP-GRIVPGVIGLMRA 4896
Query: 400 LIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKIL-----TPLTDQTVNLGKEICLKC 454
L I A DA Y+V T ++ + S +K ++++ P+ DQ V C
Sbjct: 4897 LTINDADDTDAGTYTV-TVENANNLECSSCVKVVEVIRDWLVKPIRDQHVKPKGTAIFAC 4955
Query: 455 EISENIPG-KWTK--NGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVT 511
+I+++ P KW K + +P + +D+ +++ G L I NA+ ED +Y A +
Sbjct: 4956 DIAKDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEY--AVEIEGKR 5013
Query: 512 LPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSG 571
PAK+ + + +L ++ VT+ + IS P +G+ ++ S
Sbjct: 5014 YPAKLTLGEREVELLKPIE---DVTIYEKESASFDAEISEADIPGQWKLKGE--LLRPSP 5068
Query: 572 RIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTE 630
++ L + + D +G N A ++K +DF P TV E
Sbjct: 5069 TCEIKAEGGKRFLTLHKVKLDQAGEVLYQALNAITTAILTVKEIELDFAVPLKDVTVPE 5127
Score = 86.3 bits (212), Expect = 2e-16
Identities = 78/292 (26%), Positives = 125/292 (42%), Gaps = 60/292 (20%)
Query: 265 DKGGRVRFV--VELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 322
++GG V++V +E D +V WY +++ S KY ++ IL++ + DD Y
Sbjct: 25208 EEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTY 25267
Query: 323 YVTA----GDEKCSTELFVR---------------------------EPPIMVTKQLEDT 351
G++ ELFV+ E P T L +
Sbjct: 25268 RCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNK 25327
Query: 352 TAYCGERVELECEVS-EDDANVKWFKNGEEIIPGPK-SRYRIRVEGKKHILIIEGATKAD 409
TAY GE V ++ + +V W+K+G++I PG +Y + + L I T D
Sbjct: 25328 TAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDD 25387
Query: 410 AAEYSVMTTG--GQSS--AKLSVDLKPLKILTPLTDQTV-------------NLGKEICL 452
AEY+V+ G+ S AKL+V L P P TD T+ G+ +C
Sbjct: 25388 DAEYTVVARNKYGEDSCKAKLTVTLHP-----PPTDSTLRPMFKRLLANAECQEGQSVCF 25442
Query: 453 KCEISENIPG--KWTKNGLPVQESDRLKVVHKG-RIHKLVIANALTEDEGDY 501
+ +S P KW K+G P+ ++++H+G + L I + L ED G Y
Sbjct: 25443 EIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYY 25494
Score = 85.9 bits (211), Expect = 2e-16
Identities = 115/472 (24%), Positives = 174/472 (36%), Gaps = 92/472 (19%)
Query: 693 RIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGY 752
R AVN + KP P+ P L ++ +T ++ W P G A +D Y
Sbjct: 19499 RSVAVNCKVLDKPGPPAGP------------LEINGLTAEKCSLSWGRPQEDGGADIDYY 19546
Query: 753 VLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKA 812
++E E A W + +L T +T L + RV
Sbjct: 19547 IVE-----------KRETSHLA-------WTICEGEL-QMTSCKVTKLLKGNEYIFRVTG 19587
Query: 813 VNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELT 872
VN G EP + + +K + P L+ T + + E++ L RPE
Sbjct: 19588 VNKYGVGEPL---ESVAIKALDPFTVPSPPTSLEITSVTK--ESMTLCWS-----RPE-- 19635
Query: 873 WKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQI---- 928
G+EI I R E +++ ++R ++ YDL+VK E + ++
Sbjct: 19636 -SDGGSEISGYIIERR--EKNSLRWVRVNKKP---VYDLRVKSTGLREGCEYEYRVYAEN 19689
Query: 929 -------------------IDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQ 969
+ P PP KI D + + W P DG A ITGYT++
Sbjct: 19690 AAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVE 19749
Query: 970 KADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARD 1029
+W T I+ T TI+ L G EY FRV S N G S+ + + D
Sbjct: 19750 YKKSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSS--------D 19801
Query: 1030 GKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVD 1089
+I K E ++ M +V AG + T+ RG P P + W K
Sbjct: 19802 PQIAKEREEEPLFDIDSEMRKTLIVK----AGASFTMTVPFRGRPVPNVLWSKPDT---- 19853
Query: 1090 DPRYRMF--SNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVI 1139
D R R + + +L I + D G Y N L + L VKV+
Sbjct: 19854 DLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASL--TLVVKVL 19903
Score = 85.9 bits (211), Expect = 2e-16
Identities = 128/602 (21%), Positives = 222/602 (36%), Gaps = 112/602 (18%)
Query: 581 SSTLVIDIAERDDSGV--YHINLKNEAGEAH----ASIKVKV------VDFPDPPVAPTV 628
S T I++++ + V + + KNE G + I VK VD D P A
Sbjct: 21143 SKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPITVKELIITPEVDLSDIPGAQVT 21202
Query: 629 TEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKET-TFEPKKMIEG 687
+G + ++ E P P + + + + S ++R + K T + + K G
Sbjct: 21203 VRIGHN---VHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHG 21259
Query: 688 VAYEVRI--------FAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWR 739
Y V + + I + PS P P + D + +V + W
Sbjct: 21260 GKYTVILDNAVCRIAVPITVITLGPPSKPKGP------------IRFDEIKADSVILSWD 21307
Query: 740 PPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITG 799
P+ G + Y +E T+ K + + +T F +
Sbjct: 21308 VPEDNGGGEITCYSIEKRETSQTNWKMVCSS-------------------VARTTFKVPN 21348
Query: 800 LPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNL 859
L DA+ RV+A N G S QP++ I+ + RIP G+ V
Sbjct: 21349 LVKDAEYQFRVRAENRYGVS------QPLVSSIIVAKHQFRIPGP--------PGKPVIY 21394
Query: 860 VIPFQGKPRPELTWKKD----GAEIDKNQINIRNSETDTIIFIRKAERSHSGK------- 908
+ G LTW G+E+ ++ E ++I++ + SG+
Sbjct: 21395 NVTSDGM---SLTWDAPVYDGGSEV--TGFHVEKKERNSILWQKVNTSPISGREYRATGL 21449
Query: 909 -----YDLQVKVDKFVETAS--------IDIQIIDRPGPPQIVKIEDVWGENVALTWTPP 955
Y +V + +S + + +D PG P + DV E + L W PP
Sbjct: 21450 VEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYI---DVTRETITLKWNPP 21506
Query: 956 KDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1015
DG + I GY+I+K T+T L G+ Y FR+ + N G
Sbjct: 21507 LRDGGSKIVGYSIEKRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTIS 21566
Query: 1016 DATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPK 1075
+ + ++ RD + P +F P + L+ +G + + V+G P
Sbjct: 21567 PPSQSS-GIIMTRDENV---PPIVEF----GPEYFDGLIIK---SGESLRIKALVQGRPV 21615
Query: 1076 PKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLE 1135
P++TW K+ V I + G +L +R + G Y +A N G+ + E K++
Sbjct: 21616 PRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVK 21675
Query: 1136 VK 1137
V+
Sbjct: 21676 VQ 21677
Score = 85.5 bits (210), Expect = 3e-16
Identities = 203/971 (20%), Positives = 332/971 (34%), Gaps = 208/971 (21%)
Query: 259 DPAYQVDKGGRVRFVVEL-ADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMT 317
D Y + R + + P V W K + T+ E L + +CQ +
Sbjct: 13617 DLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKS 13676
Query: 318 DDSEYYVT----AGDEKCSTELFVREPPIMVTKQL--EDTTAYC------------GERV 359
D +Y +T AG ++ + + V P + T + ++ TA G +
Sbjct: 13677 DAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEI 13736
Query: 360 ELECEVSEDDANVKWFKNGEEIIPGPKSRYRI-----------RVEGKKHILIIEGATKA 408
D N KW + K+ +R+ RV + + EG
Sbjct: 13737 TNYILEKRDSVNNKWVTCASAV---QKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSE 13793
Query: 409 DAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEIC-LKCEISENIPGKWTK- 466
VD++ + TD G I E E W +
Sbjct: 13794 PIVARHPFDVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRA 13853
Query: 467 NGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIIL 526
N P++ D KV LTE +Y F A N+ K + P + L
Sbjct: 13854 NKTPIRMRD-FKVT------------GLTEGL-EYEFRVMAINLAGVGKPSLPSEPVVAL 13899
Query: 527 DGLDAD----------NTVTVI-------AGNKLRLEIPISGEPPPKAMWSRGDKAIMEG 569
D +D N+VT+I G+KL I + P K+ W + +
Sbjct: 13900 DPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKS-WMKANHV---- 13954
Query: 570 SGRIRTESYPDSSTLVIDIAERDDSGVYH--INLKNEAGEAHA-SIKVKVVDFPDPPVAP 626
+ P+ + V D+ E G Y I KN AG A S + + D AP
Sbjct: 13955 -------NVPECAFTVTDLVE---GGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAP 14004
Query: 627 TVTEVGDDWCIMNWEPPAYDG-----GSPIL--GYFIERKKKQSSRWMRLNFDL----CK 675
T+ +P DG G I+ I K S W + D+
Sbjct: 14005 TIV----------LDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDIT 14054
Query: 676 ETTFEPKKMIEGVAYEVR-------IFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDS 728
+ T P + + Y R I A N G + L V PP + + +
Sbjct: 14055 QITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVK---VTVLDVPGPPGPVEISN 14111
Query: 729 VTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKD 788
V+ T+ W PP G + + Y+LE + TS W V ++D
Sbjct: 14112 VSAEKATLTWTPPLEDGGSPIKSYILE---KRETSRLL---------------WTVVSED 14153
Query: 789 LIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQT 848
I + T L + RV AVN G EP S+P+ + + PP
Sbjct: 14154 -IQSCRHVATKLIQGNEYIFRVSAVNHYGKGEP-VQSEPVKMVDRFGPP----------- 14200
Query: 849 YIRRVGEAVNLVIPFQGKPRPELTWKKD----GAEIDKNQINIRNSETDTIIFIRKAERS 904
G + K ++WK+ G+EI + R E ++ ++R +
Sbjct: 14201 -----GPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERR--EKKSLRWVRAIKTP 14253
Query: 905 HSGKYDLQVKVDKFVETASIDIQIIDR-----------------------PGPPQIVKIE 941
S DL+ KV E ++ + ++ PGPP +
Sbjct: 14254 VS---DLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVT 14310
Query: 942 DVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGN-- 999
D ++ +L W P DG ITGY ++ W I+ T+ IT+ V+ +
Sbjct: 14311 DTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAW---IKDTTGTALRITQFVVPDLQ 14367
Query: 1000 ---EYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNT 1056
+Y FR+ + N G+ E A + D +I + + DF+ L T
Sbjct: 14368 TKEKYNFRISAINDAGVGEPAVIP--------DVEIVEREMAPDFELDAE------LRRT 14413
Query: 1057 YAI-AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGG 1115
+ AG + + ++G P P++TW K+ + + + R + + + L I + + YD G
Sbjct: 14414 LVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKN--RANIENTESFTLLIIPECNRYDTG 14471
Query: 1116 TYCCKAVNDLG 1126
+ N G
Sbjct: 14472 KFVMTIENPAG 14482
Score = 85.1 bits (209), Expect = 3e-16
Identities = 105/480 (21%), Positives = 179/480 (37%), Gaps = 70/480 (14%)
Query: 672 DLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTD 731
D C+E + A E I +N I + KP P+ P + +D VT
Sbjct: 15837 DACREDVGHYVVKLTNSAGEA-IETLNVIVLDKPGPPTGP------------VKMDEVTA 15883
Query: 732 TTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLID 791
++T+ W PP + G + ++ Y++E D W + + +
Sbjct: 15884 DSITLSWGPPKYDGGSSINNYIVE------------------KRDTSTTTWQIVSAT-VA 15924
Query: 792 KTKFTITGLPTDAKIFVRVKAVNAAGAS-----EPKYYSQPILVKEIIEPPKIRIPRH-- 844
+T L T + R+ A N G S EP P V P + +
Sbjct: 15925 RTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDS 15984
Query: 845 LKQTYIRRVGEAVNLVIPF--QGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAE 902
++ + + + + VI + + K R + W K ++K I +T + + E
Sbjct: 15985 MEVQWNEPISDGGSRVIGYHLERKERNSILWVK----LNKTPIPQTKFKTTGLEEGVEYE 16040
Query: 903 RSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAA 962
S + + + V + D PG P+ + + +V L W P DG +
Sbjct: 16041 FRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIIVTR---NSVTLQWKKPTYDGGSK 16097
Query: 963 ITGYTIQKADKKSMEWFTV-IEHYHRTSATITELVIGNEYYFRVFSENMCGL-SEDATMT 1020
ITGY ++K + W + T +T LV + Y FRV + N G+ SE + T
Sbjct: 16098 ITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSEST 16157
Query: 1021 KESAVIARDG----KIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKP 1076
A+ ARD +I +P Y+D AG + ++ + G P P
Sbjct: 16158 --GAITARDEVDPPRISMDPKYKD--------------TIVVHAGESFKVDADIYGKPIP 16201
Query: 1077 KITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
I W+K + + R + S +L ++ D G Y KA N G + ++V
Sbjct: 16202 TIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKV 16261
Score = 85.1 bits (209), Expect = 3e-16
Identities = 100/435 (22%), Positives = 171/435 (39%), Gaps = 65/435 (14%)
Query: 720 PPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPA 779
PP + +D V+ ++T+ W PP++ G + Y++E ST+
Sbjct: 19118 PPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTT---------------- 19161
Query: 780 EDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPP-- 837
W + ++ + +T I L T ++ RV A N G S S ++ + PP
Sbjct: 19162 --WHIVSQ-AVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSE-SSAVVAEYPFSPPGP 19217
Query: 838 --KIRIPRHLKQTYIRR----VGEAVNLVIPF--QGKPRPELTWKKDGAEIDKNQINIRN 889
++ K T + V + + VI + + K R + W K N+I I
Sbjct: 19218 PGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSK------ANKILI-- 19269
Query: 890 SETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQII------DRPGPPQIVKIEDV 943
DT + + + +Y + + + S + + D PG P++ I
Sbjct: 19270 --ADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTNITR- 19326
Query: 944 WGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV-IEHYHRTSATITELVIGNEYY 1002
++V+L W+ P DG A ITGY +++ + W + T +TEL Y
Sbjct: 19327 --KSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFEVTELTEDQRYE 19384
Query: 1003 FRVFSENMC-GLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAG 1061
FRVF+ N +SE + T +I +D + V D F + + AG
Sbjct: 19385 FRVFARNAADSVSEPSEST--GPIIVKDD-VEPPRVMMDVKFRDVIVVK---------AG 19432
Query: 1062 YNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKA 1121
+N + G P P I+W K+ + I + R + S L ++ D G Y
Sbjct: 19433 EVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTL 19492
Query: 1122 VNDLGT--VEIECKL 1134
N GT V + CK+
Sbjct: 19493 KNVAGTRSVAVNCKV 19507
Score = 84.0 bits (206), Expect = 8e-16
Identities = 93/410 (22%), Positives = 160/410 (39%), Gaps = 66/410 (16%)
Query: 263 QVDKGGRVRFVVELADPKLEVKWYKNGQEI----RPSTKYIFEHKGCQRILFINNCQMTD 318
QV + R E+ + ++ WYK+G EI + KY+ E + +FI+ + +D
Sbjct: 3111 QVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERR--IHRMFISETRQSD 3168
Query: 319 DSEYYVTAGDEKCSTELFVREP-PIMVTKQLEDTTAYCGERVELECEVS-EDDANVKWFK 376
EY AG + S L+V P P V ++L+ T G+ +S + W+K
Sbjct: 3169 AGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYK 3228
Query: 377 NGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAA--------EYSVMTTGGQSSAKL-- 426
+ + G K ++ +G+++ L++ A DAA +Y V TT S ++
Sbjct: 3229 EEQLLSTGFKCKF--LHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPE 3286
Query: 427 ------SVDLKPLKILTPLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKV 479
+ + P I+TPL D + G+ +C +S ++ W ++ S ++
Sbjct: 3287 VVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRM 3346
Query: 480 VHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLD--ADNT--- 534
++L IA A EDEG Y F V A V + L+G +NT
Sbjct: 3347 TQFEDTYQLEIAEAYPEDEGTYTF------VASNAVGQVSSTANLSLEGFSKFEENTSNS 3400
Query: 535 ---------------------------VTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIM 567
+ V G +R +SG P P+ W + I+
Sbjct: 3401 QWHVSLSVSFKKEPLGQKPSFIQPLSSLRVHNGETVRFHARVSGIPKPEIQWFHNQQLIL 3460
Query: 568 EGSGRI-RTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKV 616
+ E + ++I A + +G Y N AGEA + + V
Sbjct: 3461 PTKDVVFHFEESTGMALMLIVDAYSEHAGQYSCKAANSAGEATCAATLTV 3510
Score = 84.0 bits (206), Expect = 8e-16
Identities = 100/460 (21%), Positives = 169/460 (36%), Gaps = 78/460 (16%)
Query: 697 VNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEY 756
+ + + P P PF + + ++ W P G + + Y++E
Sbjct: 12612 IKVVVMDAPGPPQPPF------------DISDIDADACSLSWHIPLEDGGSNITNYIVEK 12659
Query: 757 CFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAA 816
C D+ DW+ A + KT + L + RV+A N
Sbjct: 12660 C------------------DVSRGDWVTALAS-VTKTSCRVGKLIPGQEYIFRVRAENRF 12700
Query: 817 GASEPKYYSQPILVKEI-----IEPPKIRIPRHLKQ----TYIRRVGEAVNLVIPF--QG 865
G SEP + P +V + EP R+ + K + R + + +I + +
Sbjct: 12701 GISEP--LTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIER 12758
Query: 866 KPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERS------HSGKYDLQVKVDKFV 919
K R L W K N +R++E + E S + K ++V
Sbjct: 12759 KERNSLLWVK------ANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYV 12812
Query: 920 ETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF 979
TA + + D PG P+++ DV V+L W PK DG + I GY ++ +W
Sbjct: 12813 -TARMPV---DPPGKPEVI---DVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWV 12865
Query: 980 ---TVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNP 1036
T + T T L +Y FR + +S + + ++A + P
Sbjct: 12866 RCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENV-----P 12920
Query: 1037 VYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMF 1096
D + + T AG N L+ +V G P P ++W K+ + +M
Sbjct: 12921 PRIDLSVAMKSLLTVK-------AGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMA 12973
Query: 1097 SNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
+ +CTLE+ + D G Y A N G+ KL+V
Sbjct: 12974 MQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKV 13013
Score = 82.8 bits (203), Expect = 2e-15
Identities = 59/194 (30%), Positives = 92/194 (47%), Gaps = 21/194 (10%)
Query: 547 IPISGEPPPKAMWSRGDKAIMEGSGRIRTE-------SYPDSSTLVIDIAERDDSGVYHI 599
+ + EPP + ++E R+ T + PD + V D+ E + + +
Sbjct: 7828 VDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQ-FQV 7886
Query: 600 NLKNEAGEAHASIKVKVVDFPDPPVAPT------VTEVGDDWCIMNWEPPAYDGGSPILG 653
+NEAG H S +++ DP P+ VT+ G + W+PP +GGSPI+G
Sbjct: 7887 RAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIG 7946
Query: 654 YFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVA----YEVRIFAVNAIGISKPSMPS 709
Y +E + +WMR+N K+ F K+ EGV Y +R+ AVNAIG+S+PS S
Sbjct: 7947 YHVEMCPVGTEKWMRVNSRPIKDLKF---KVEEGVVPDKEYVLRVRAVNAIGVSEPSEIS 8003
Query: 710 RPFVPLAVTSPPTL 723
V PT+
Sbjct: 8004 ENVVAKDPDCKPTI 8017
Score = 77.8 bits (190), Expect = 5e-14
Identities = 104/452 (23%), Positives = 164/452 (36%), Gaps = 62/452 (13%)
Query: 697 VNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEY 756
++ I + KP P P + D V+ V + W PP + G + Y++E
Sbjct: 18025 LSVIVLEKPGPPVGP------------VRFDEVSADFVVISWEPPAYTGGCQISNYIVE- 18071
Query: 757 CFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAA 816
D W + + + +T IT L T + R+ A N
Sbjct: 18072 -----------------KRDTTTTTWHMVSAT-VARTTIKITKLKTGTEYQFRIFAENRY 18113
Query: 817 GASEPKYYSQPILV----KEIIEPPKIRIPRHLKQTYIRRVGEAVN------LVIPFQGK 866
G S P S+ ++V KE P + K + + E VN + + K
Sbjct: 18114 GKSAP-LDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQK 18172
Query: 867 PRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDI 926
+ + W K ++K I +T + + E S + + + V +
Sbjct: 18173 EKNSILWVK----LNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVAR 18228
Query: 927 QIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV-IEHY 985
D PG P+ + I NV L W P DG + ITGY ++K D W +
Sbjct: 18229 DPCDPPGRPEAIVITR---NNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNV 18285
Query: 986 HRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSE 1045
T T++ LV Y FRV + N G + + A+ ARD N +
Sbjct: 18286 LETEFTVSGLVEDQRYEFRVIARNAAGNFSEPS-DSSGAITARDEIDAPNASLD------ 18338
Query: 1046 APMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDD-PRYRMFSNQGVCTL 1104
P + +V AG L +RG P P + W K+ + + R + S TL
Sbjct: 18339 -PKYKDVIV---VHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTL 18394
Query: 1105 EIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
++ DGG Y K N GT I ++V
Sbjct: 18395 VVKDCIRTDGGQYILKLSNVGGTKSIPITVKV 18426
Score = 77.4 bits (189), Expect = 7e-14
Identities = 102/462 (22%), Positives = 169/462 (36%), Gaps = 81/462 (17%)
Query: 696 AVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLE 755
++ + + KP P P + D V+ ++T+ W PP + G + Y+++
Sbjct: 16942 SIEIVTLDKPDPPKGP------------VKFDDVSAESITLSWNPPLYTGGCQITNYIVQ 16989
Query: 756 YCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNA 815
D W V + + +T +T L T + R+ A N
Sbjct: 16990 ------------------KRDTTTTVWDVVSAT-VARTTLKVTKLKTGTEYQFRIFAENR 17030
Query: 816 AGASEPKYYSQPILVKEIIE---PPKIRIPRHL-KQTYIRRVGEAVN------LVIPFQG 865
G S S PI+ + + PP + K + + + E VN + +
Sbjct: 17031 YGQSFA-LESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLER 17089
Query: 866 KPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSG-KYDLQVKVDKFVETAS- 923
K R + W K ++K I+ DT KA+ G +Y+ +V + V
Sbjct: 17090 KERNSILWTK----VNKTIIH------DTQF---KAQNLEEGIEYEFRVYAENIVGVGKA 17136
Query: 924 -------IDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSM 976
+ D PG P+ + ++ + L WT P DG + ITGY ++K D
Sbjct: 17137 SKNSECYVARDPCDPPGTPEPIMVKR---NEITLQWTKPVYDGGSMITGYIVEKRDLPDG 17193
Query: 977 EWFTV-IEHYHRTSATITELVIGNEYYFRVFSENMCG-LSEDATMTKESAVIARDGKIYK 1034
W + T T++ L Y FRV ++N G +S+ + T G I
Sbjct: 17194 RWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDST---------GPITA 17244
Query: 1035 NPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYR 1094
E S P F +V AG L V G P P I W++ I + R
Sbjct: 17245 KDEVELPRISMDPKFRDTIVVN---AGETFRLEADVHGKPLPTIEWLRGDKEIEESARCE 17301
Query: 1095 MFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
+ + L ++ DGG Y +A N G+ ++V
Sbjct: 17302 IKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKV 17343
Score = 77.0 bits (188), Expect = 9e-14
Identities = 106/469 (22%), Positives = 169/469 (36%), Gaps = 97/469 (20%)
Query: 697 VNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEY 756
+ I + KP P+ P + +D + T++T+ W PP+ G A L GYV+E
Sbjct: 23452 IKVIILDKPGPPTGP------------IKIDEIDATSITISWEPPELDGGAPLSGYVVEQ 23499
Query: 757 CFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAA 816
D W+ ++ + ++ F T L + RV A N
Sbjct: 23500 ------------------RDAHRPGWLPVSES-VTRSTFKFTRLTEGNEYVFRVAATNRF 23540
Query: 817 GASEPKYYSQPILVKEIIE-PPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTW-- 873
G L E+IE IRIP G L I + LTW
Sbjct: 23541 GIGS-------YLQSEVIECRSSIRIP-----------GPPETLQIFDVSRDGMTLTWYP 23582
Query: 874 -KKDGAE------IDKNQINIR-----NSETDTIIFIRKAERSHSGKYDLQVKVDKFVET 921
+ DG +++ ++ N T+ R + +Y+ +V +
Sbjct: 23583 PEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGS 23642
Query: 922 AS--------IDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADK 973
+ + I PG PQ ++ D +V+L W+ P+D+G + +TGY I+
Sbjct: 23643 GKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKV 23702
Query: 974 KSMEWF------TVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIA 1027
EW T I Y T+T L G EY FRV + N G E A +
Sbjct: 23703 DQHEWTKCNTTPTKIREY-----TLTHLPQGAEYRFRVLACNAGGPGEPAE-------VP 23750
Query: 1028 RDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAI 1087
K+ + Y D++ E + + G L ++G P P W K I
Sbjct: 23751 GTVKVTEMLEYPDYELDE-----RYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDI 23805
Query: 1088 VDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
R + +++ L I++ D GTY N G + K+ V
Sbjct: 23806 --SKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRV 23852
Score = 73.9 bits (180), Expect = 8e-13
Identities = 64/235 (27%), Positives = 91/235 (38%), Gaps = 46/235 (19%)
Query: 932 PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRT-SA 990
P PP V++ + E + +TW PP DG + I GY I+K K W EH +
Sbjct: 8208 PDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTY 8267
Query: 991 TITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFT 1050
T L G EY FRV +EN G+SE + T + + + D + + T
Sbjct: 8268 TAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAV------------DPIDAPKVILRT 8315
Query: 1051 QPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDD-------PRYRM-------- 1095
V G L+ S+ G+P P ITW+K++ IV + P R
Sbjct: 8316 SLEVKR----GDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEE 8371
Query: 1096 --------------FSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
S +G L +R D G Y K ND G + C + V
Sbjct: 8372 EPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSV 8426
Score = 73.9 bits (180), Expect = 8e-13
Identities = 59/203 (29%), Positives = 83/203 (40%), Gaps = 14/203 (6%)
Query: 926 IQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHY 985
++ + P PP + I D+ V+L W PK DG + ITGY I+ K S +W T I
Sbjct: 14587 VKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQW-THITTV 14645
Query: 986 HRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSE 1045
+ L G EY F+V + N G S +ES + + + + + D
Sbjct: 14646 KGLECVVRNLTEGEEYTFQVMAVNSAGRSAP----RESRPVI----VKEQTMLPELDLRG 14697
Query: 1046 APMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLE 1105
Q LV A AG N + V G PKP +TW K + R + L
Sbjct: 14698 ---IYQKLV--IAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILN 14752
Query: 1106 IRKPSPYDGGTYCCKAVNDLGTV 1128
I + D G Y A N +G V
Sbjct: 14753 INECVRSDSGPYPLTARNIVGEV 14775
Score = 73.2 bits (178), Expect = 1e-12
Identities = 52/197 (26%), Positives = 86/197 (43%), Gaps = 13/197 (6%)
Query: 930 DRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTS 989
++P PP+ + + D + L W P DG + ITGY ++ K S W H + +
Sbjct: 22172 EQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEA-GHTKQLT 22230
Query: 990 ATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMF 1049
T+ LV EY FRV ++N G SE S+VI ++ +I ++
Sbjct: 22231 FTVERLVEKTEYEFRVKAKNDAGYSEPREAF--SSVIIKEPQIEPT--------ADLTGI 22280
Query: 1050 TQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKP 1109
T L+ A G T++ + G P PK+TW ++ + + R + + + TL ++
Sbjct: 22281 TNQLITCKA--GSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDS 22338
Query: 1110 SPYDGGTYCCKAVNDLG 1126
D G Y N G
Sbjct: 22339 MRGDSGRYFLTLENTAG 22355
Score = 72.4 bits (176), Expect = 2e-12
Identities = 56/222 (25%), Positives = 101/222 (45%), Gaps = 17/222 (7%)
Query: 918 FVETASIDI--QIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKS 975
FVET+ + + I P P+ +++++V V LTW PPK DG + I Y ++ +
Sbjct: 10329 FVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGT 10388
Query: 976 MEWFTVI-EHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYK 1034
++ V ++ T+ L G+ Y +RV + N+ G + + TK I ++
Sbjct: 10389 EKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKP---ITCKDELAP 10445
Query: 1035 NPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYR 1094
++ DF T + +A+ G + G PKPK++W K++ +++D R
Sbjct: 10446 PTLHLDF----RDKLTIRVGEAFALTGRYS-------GKPKPKVSWFKDEADVLEDDRTH 10494
Query: 1095 MFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
+ + LE K D G YC N G+ + C++ V
Sbjct: 10495 IKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNV 10536
Score = 71.6 bits (174), Expect = 4e-12
Identities = 134/663 (20%), Positives = 230/663 (34%), Gaps = 120/663 (18%)
Query: 2 PEPTKKEENEVPAP----APPPEEPSKEKEAGTTPAKDWTLVETPPGEEQAKQNANSQLS 57
PEP K V +P +P P P T P TP + Q +
Sbjct: 26297 PEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKP--------TPTEKVQHLPVSAPPKI 26348
Query: 58 ILFIEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAGKHLQLKETFE 117
F++ + ++I + V +LR + W+K GK L+ F+
Sbjct: 26349 TQFLK------AEASKEIAKLTCVVESSVLRAKEVTWYKD---------GKKLKENGHFQ 26393
Query: 118 RH-SRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFK 176
H S T+E++I ++ G Y CE+
Sbjct: 26394 FHYSADGTYELKINNLTESDQGEYVCEI-------------------------------- 26421
Query: 177 RSGEGQEDAGELDFSG---------LLKRREVKQQEEEPQVDVWELLKNAKPSEYEKIAF 227
SGEG L F G + K E K+ +++ + + +P E I+
Sbjct: 26422 -SGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTEST--VTRKTEPKAPEPIS- 26477
Query: 228 QYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYK 287
K + D D + V +P+ W K
Sbjct: 26478 ---------------------SKPVIVTGLQDTTVSSDSVAKFA-VKATGEPRPTAIWTK 26515
Query: 288 NGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVT----AGDEKCSTELFVREPPIM 343
+G+ I KY L I+ +D Y T AG S +L ++ I
Sbjct: 26516 DGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKA--IK 26573
Query: 344 VTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIE 403
T+ + +T E + V +++ + K ++ E + KS+ ++ ++ + ++I
Sbjct: 26574 DTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLALKEEASKVLIS 26633
Query: 404 GATKADAA---EYSVMTTGGQSSAKLSVDLKP-LKILTPLTDQTVNLGKEICLKCEISEN 459
K AA E S++ +++ S +++ +I T ++N G+ + LK I+
Sbjct: 26634 EEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGA 26693
Query: 460 IPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV--------FAPDAYNVT 511
KW NG+ + S+ + G L I A DEG Y++T
Sbjct: 26694 TDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLT 26753
Query: 512 LPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSG 571
L ++ D P I + + G + ISGEP P+ W + + I S
Sbjct: 26754 LSKELS--DAPAFI----SQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPI-SISS 26806
Query: 572 RIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEV 631
+ + +L I A DSG Y I KN G+ A+ + V+ + P V
Sbjct: 26807 NVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRT 26866
Query: 632 GDD 634
D
Sbjct: 26867 SGD 26869
Score = 68.9 bits (167), Expect = 3e-11
Identities = 107/465 (23%), Positives = 175/465 (37%), Gaps = 76/465 (16%)
Query: 696 AVNAIGISKPSMPSR-PFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVL 754
A NA G +K + + P V P + ++T +T+ W P + G A + Y++
Sbjct: 21661 AKNASGSAKAEIKVKVQDTPGKVVGP---IRFTNITGEKMTLWWDAPLNDGCAPITHYII 21717
Query: 755 EYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVN 814
E E A+ L +D + +T L + RV AVN
Sbjct: 21718 E-----------KRETSRLAWALI--------EDKCEAQSYTAIKLINGNEYQFRVSAVN 21758
Query: 815 AAGASEPKYYSQPILVK---EIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPEL 871
G P S P++ + + + P I P ++ G ++ L RPE
Sbjct: 21759 KFGVGRP-LDSDPVVAQIQYTVPDAPGIPEPSNI-------TGNSITLTWA-----RPE- 21804
Query: 872 TWKKDGAEIDKNQINIRNSE-TDTIIFIRKAERSHS----------GKYDLQVKVDKF-- 918
G+EI + + R + T + I K S + +Y+ V +
Sbjct: 21805 --SDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAG 21862
Query: 919 VETASIDIQII------DRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKAD 972
V AS ++I + PGPP +VK+ D V+L W+ P DG I GY I+
Sbjct: 21863 VGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCK 21922
Query: 973 KKSMEWFTV-IEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGK 1031
+W V E +T T+T+L G EY FRV + N G + +T I +
Sbjct: 21923 ADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVT---GTIKAVDR 21979
Query: 1032 IYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDP 1091
+ + D +F + + AG + L + +G P P W K +
Sbjct: 21980 LTAPELDIDANFKQTHVVR---------AGASIRLFIAYQGRPTPTAVWSKPDSNL--SL 22028
Query: 1092 RYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
R + + TL + + D G Y N+ G+ I ++V
Sbjct: 22029 RADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKV 22073
Score = 64.7 bits (156), Expect = 5e-10
Identities = 75/303 (24%), Positives = 129/303 (42%), Gaps = 19/303 (6%)
Query: 341 PIMVTKQLEDT----TAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGK 396
P+ K+++D + + G EC VS A W K+G I PK +R +GK
Sbjct: 4742 PLKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPK--HRFIADGK 4799
Query: 397 KHILIIEGATKADAAEYSVMTTGGQ----SSAKLSVDLKPLKILTPLTDQ-TVNLGKEIC 451
L I +DA EY+ + G S+AKL V+ P++ + L ++ TV G+ +
Sbjct: 4800 DRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLY 4859
Query: 452 LKCEISENIPGKWTKNG-LPVQESDRLKVVHKGRIHKLVIANALTEDEGDY-VFAPDAYN 509
L CE+++ W K+G + V++ R+ G + L I +A D G Y V +A N
Sbjct: 4860 LSCELNKERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVENANN 4919
Query: 510 VTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEG 569
+ + V V++ +I D L + + + P W +G I
Sbjct: 4920 LECSSCVKVVE---VIRDWLVKPIRDQHVKPKGTAIFACDIAKDTPNIKWFKGYDEI-PA 4975
Query: 570 SGRIRTESYPDSSTLVIDI--AERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT 627
+TE D + L + I A +D Y + ++ + A ++ + V+ P T
Sbjct: 4976 EPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGKRYPAKLTLGEREVELLKPIEDVT 5035
Query: 628 VTE 630
+ E
Sbjct: 5036 IYE 5038
Score = 63.5 bits (153), Expect = 1e-09
Identities = 31/92 (33%), Positives = 43/92 (46%)
Query: 1047 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEI 1106
P L N I G + TL C + G P P +TW + I +++ G+ L I
Sbjct: 897 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMI 956
Query: 1107 RKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1138
R+ D G + C AVN+ GTV C L V+V
Sbjct: 957 REAFAEDSGRFTCSAVNEAGTVSTSCYLAVQV 988
Score = 61.2 bits (147), Expect = 5e-09
Identities = 33/100 (33%), Positives = 54/100 (54%), Gaps = 6/100 (6%)
Query: 931 RPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEH-YHRTS 989
RP PP++ K+ E + + W PP+ DG +ITGY ++K +K S W V +
Sbjct: 12026 RPDPPEVTKVSK---EEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERR 12082
Query: 990 ATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARD 1029
+ L+ +EY FRV +EN G+ E + ++ V+A+D
Sbjct: 12083 MKVQNLLPDHEYQFRVKAENEIGIGEPSLPSR--PVVAKD 12120
Score = 59.7 bits (143), Expect = 2e-08
Identities = 74/324 (22%), Positives = 129/324 (39%), Gaps = 19/324 (5%)
Query: 829 LVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQ--GKPRPELTWKKDGAEID----- 881
L +E P + P + + ++++ E ++V Q G P+P + WKK G +
Sbjct: 1023 LTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRY 1082
Query: 882 KNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIE 941
K N + E +I + A+ +G+Y + V+ +K ET S +++ ++K +
Sbjct: 1083 KVSYNKQTGECKLVISMTFAD--DAGEYTIVVR-NKHGET-SASASLLEEADYELLMKSQ 1138
Query: 942 DVWGENVALTWTPPKDDGNAAITGYTIQKADKK-SMEWFTVIEHYHRTSATITELVIGNE 1000
+T + G+ + +K+ E + + + + + V E
Sbjct: 1139 QEMLYQTQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDTVVVRTYVEDQE 1198
Query: 1001 YYFRVFSENMCGLSEDATM-TKESAVIARDGKIYKNPVYEDFDFSEAPM--FTQPLVNTY 1057
++ F E + E + T ++ DG+ + D SEA F + N
Sbjct: 1199 FHISSFEERLIKEIEYRIIKTTLEELLEEDGE---EKMAVDISESEAVESGFDSRIKNYR 1255
Query: 1058 AIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRM-FSNQGVCTLEIRKPSPYDGGT 1116
+ G T +C + G P PKI W K+ I RY+M F G +L I P D G
Sbjct: 1256 ILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGI 1315
Query: 1117 YCCKAVNDLGTVEIECKLEVKVIA 1140
Y A N G KL V+ A
Sbjct: 1316 YTAFASNIKGNAICSGKLYVEPAA 1339
Score = 59.3 bits (142), Expect = 2e-08
Identities = 96/426 (22%), Positives = 148/426 (34%), Gaps = 58/426 (13%)
Query: 717 VTSPPT-LLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAY 775
+ PPT + D V+ VT W PP++ G + YV+E ST+
Sbjct: 14786 IPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTT------------ 14833
Query: 776 DLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIE 835
W+ +I +T + T L T + RVKA N G P S I+
Sbjct: 14834 ------WVELATTVI-RTTYKATRLTTGLEYQFRVKAQNRYGVG-PGITSACIVANY--- 14882
Query: 836 PPKIRIPRHLKQ-TYIRRVGEAVNLVIPF------------QGKPRPELTWKKDGAEIDK 882
P K+ P Q T + + ++ P + K R + W+ +
Sbjct: 14883 PFKVPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVP 14942
Query: 883 NQINIRNSETDTIIF-IRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIE 941
I + TD I + R + +GK K K E + + ID PG P + I
Sbjct: 14943 GNIFKSSGLTDGIAYEFRVIAENMAGKS----KPSKPSEPM-LALDPIDPPGKPVPLNIT 14997
Query: 942 DVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV-IEHYHRTSATITELVIGNE 1000
V L W P+ G IT Y ++K D + W + T++ L
Sbjct: 14998 R---HTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAA 15054
Query: 1001 YYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIA 1060
Y FRV ++N G + ++ D + K V D F + + A
Sbjct: 15055 YEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKV--DVKFKDTVILK---------A 15103
Query: 1061 GYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCK 1120
G L V G P P + W K+ + + + L + + D G Y
Sbjct: 15104 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLT 15163
Query: 1121 AVNDLG 1126
A N G
Sbjct: 15164 ATNPGG 15169
Score = 57.4 bits (137), Expect = 8e-08
Identities = 95/406 (23%), Positives = 148/406 (36%), Gaps = 54/406 (13%)
Query: 694 IFAVNAIGISKPSMPSRPFVPLAVTSPPT-LLTVDSVTDTTVTMRWRPPDHIGAAGLDGY 752
I AVN +G + M L PP + +SV+ +T+ W PP G + + Y
Sbjct: 9824 ITAVNNLGTASKEMRLNV---LGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNY 9880
Query: 753 VLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKA 812
V+E + + W+ + + + T +TI L + R+ A
Sbjct: 9881 VIE------------------KREANRKTWVHVSSEPKECT-YTIPKLLEGHEYVFRIMA 9921
Query: 813 VNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIP-FQGKPRPEL 871
N G EP S+P + + P P + + R VN P + G
Sbjct: 9922 QNKYGIGEP-LDSEPETARNLFSVPGA--PDKPTVSSVTRNSMTVNWEEPEYDGGSPVTG 9978
Query: 872 TW--KKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKF----VETASID 925
W KD ++N + T+ K G D Q +V V AS+
Sbjct: 9979 YWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEGS-DYQFRVYAINAAGVGPASLP 10037
Query: 926 IQI------IDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF 979
I PGPP K+ D + L W+PP DG + +TGY ++ ++ EW
Sbjct: 10038 SDPATARDPIAPPGPP-FPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWE 10096
Query: 980 TVIEHYHR-TSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVY 1038
+ R T +T L G Y FRV + N+ G+ E +T VI ++ +
Sbjct: 10097 KGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTD---VIEMKDRLVSPDLQ 10153
Query: 1039 EDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNK 1084
D + AG + V G P P +TW N+
Sbjct: 10154 LDASVRD---------RIVVHAGGVIRIIAYVSGKPPPTVTWNMNE 10190
Score = 57.0 bits (136), Expect = 1e-07
Identities = 43/167 (25%), Positives = 72/167 (43%), Gaps = 11/167 (6%)
Query: 345 TKQLEDTTAYCGERVELECEVSEDDA-NVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIE 403
T+ L+ G E +S V WF++G+ I +I + L I
Sbjct: 9 TQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIP 68
Query: 404 GATKADAAEYSVMTTGGQSSAKLSVDL------KPLKILTPLTDQTVNLGKEICLKCEIS 457
TKA++ YS+ T G A + +L P + L TV G ++ L+ ++
Sbjct: 69 AVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVT 128
Query: 458 ENIPG---KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 501
IP K+ ++G +Q S ++ +G ++ L+IA A ED G Y
Sbjct: 129 -GIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTY 174
Score = 56.6 bits (135), Expect = 1e-07
Identities = 39/140 (27%), Positives = 56/140 (40%), Gaps = 9/140 (6%)
Query: 1003 FRVFSENMCGLSEDATM---TKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI 1059
F+ E + +SE T ES V + P+ S P+ L +T
Sbjct: 26439 FKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPI------SSKPVIVTGLQDTTVS 26492
Query: 1060 AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCC 1119
+ A G P+P W K+ AI +Y++ ++G LEI K D G Y C
Sbjct: 26493 SDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTC 26552
Query: 1120 KAVNDLGTVEIECKLEVKVI 1139
N G+V CKL +K I
Sbjct: 26553 TVKNSAGSVSSSCKLTIKAI 26572
Score = 56.6 bits (135), Expect = 1e-07
Identities = 74/348 (21%), Positives = 121/348 (34%), Gaps = 77/348 (22%)
Query: 865 GKPRPELTWKKDGAEIDKN-QINIRNSETDTIIFIRKAERSHSGKYD------------- 910
G+PRP W KDG I + + + + + I K + S SG Y
Sbjct: 26505 GEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSS 26564
Query: 911 --LQVKVDKFVETASIDIQIIDRPGPPQIVKIED------VWGENVALTWTPP------K 956
L +K K E + Q P + +++ + E + ++ K
Sbjct: 26565 CKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLALK 26624
Query: 957 DDGNAAITGYTIQKADKKSMEWFTVIEHYHRTS-------------ATITELVIGNEYYF 1003
++ + + ++K+ S+E V E +TS A T++ I NE
Sbjct: 26625 EEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSI-NEGQR 26683
Query: 1004 RVFSENMCGLSE-----------------------DATMT------KESAVIARDGKIYK 1034
V N+ G ++ D T+T ++ ++ K +
Sbjct: 26684 LVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKE 26743
Query: 1035 NPVYEDFDF------SEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIV 1088
V +D S+AP F + G N C + G P P+I W KN + I
Sbjct: 26744 GIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPIS 26803
Query: 1089 DDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
+ ++ V +LEIR S D G Y KA N G L V
Sbjct: 26804 ISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 26851
Score = 54.7 bits (130), Expect = 5e-07
Identities = 52/221 (23%), Positives = 77/221 (34%), Gaps = 45/221 (20%)
Query: 920 ETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF 979
+TA D++++ RP P E W DG + YT +
Sbjct: 1426 QTARFDLKVVGRPMP------ETFWFH-----------DGQQIVNDYTHK---------- 1458
Query: 980 TVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYE 1039
VI+ S I + + V ++N G S + + AV
Sbjct: 1459 VVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAV-------------- 1504
Query: 1040 DFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDD--PRYRMFS 1097
+ PMF + L N G + GNP P I W+KN IV P+ R+
Sbjct: 1505 --EHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEG 1562
Query: 1098 NQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1138
+G L+I D Y A+N G CK+ V+V
Sbjct: 1563 TKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEV 1603
Score = 52.8 bits (125), Expect = 2e-06
Identities = 86/414 (20%), Positives = 162/414 (39%), Gaps = 69/414 (16%)
Query: 263 QVDKGGRVRFVVELAD-PKLEVKWYKNGQEIRPSTKYIF--EHKGCQRILFINNCQMTDD 319
+V G VRF ++ PK E++W+ N Q I P+ +F E ++ I +
Sbjct: 3429 RVHNGETVRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHFEESTGMALMLIVDAYSEHA 3488
Query: 320 SEYYV----TAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWF 375
+Y +AG+ C+ L VT + ++ + ER+E E E+ + + +
Sbjct: 3489 GQYSCKAANSAGEATCAATL-------TVTPKAPESILH--ERIEQEIEMEMKEFSSSFL 3539
Query: 376 KNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKI 435
EE + + + ++ +L +E V T S + + +
Sbjct: 3540 SAEEEGLHSAELQLS-KINETLELL----------SESPVYPTKFDSEKEGTGPI----F 3584
Query: 436 LTPLTDQTVNLGKEICLKCEISENIPG---KWTKNGLPVQESDRLKVVHKGRIHKLVIAN 492
+ +++ +++G L + IP +W NG+ + S K V G H L+I
Sbjct: 3585 IKEVSNADISMGDVATLSVTVI-GIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILF 3643
Query: 493 ALTEDEGDYV-FAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRL------ 545
EDEG+Y A + Y T+ + I+ +G T + +A + +L
Sbjct: 3644 TKLEDEGEYTCMASNDYGKTICSAYLKINSKG---EGHKDTETESAVAKSLEKLGGPCPP 3700
Query: 546 -------------------EIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVI 586
E + GEP P W + +K + + S T ++
Sbjct: 3701 HFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIV 3760
Query: 587 DIAERDDSGVYHINLKNEAGEAHASIKVKVV----DFPDPPV-APTVTEVGDDW 635
+ +R+DSG+Y +N GE+ + ++ V+ D D P A + E +D+
Sbjct: 3761 NDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTPCKAKSTPEAPEDF 3814
Score = 51.2 bits (121), Expect = 5e-06
Identities = 56/305 (18%), Positives = 122/305 (40%), Gaps = 22/305 (7%)
Query: 842 PRHLKQTYIRRVGEAVNLVIPFQ--GKPRPELTWKKDGAEID-KNQINIRNSETDTIIFI 898
P + Q + + E N++ + G+P PE+ W K+ I + ++I S + I
Sbjct: 26762 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEI 26821
Query: 899 RKAERSHSGKYDLQVKVDKFVETASIDIQIIDR-PGPPQIVKIEDVWGENVALTWTPPKD 957
R A S SGKY ++ K + +A+ + ++ P + V + ++ +++
Sbjct: 26822 RNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFSSQSV 26881
Query: 958 DGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDA 1017
+A+ + S T ++ ++ +++ + E + + S + G+S
Sbjct: 26882 QMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSM---QESFVEMSSSSFMGISNMT 26938
Query: 1018 TMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI-AGYNATLNCSVRGNPKP 1076
+ ++ + + G P + L + +I G T+ C+ G P P
Sbjct: 26939 QLESSTSKMLKAG------------IRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTP 26986
Query: 1077 KITWM--KNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKL 1134
++TW K+ + R+ + + + TL I DGG Y N+ G+ +
Sbjct: 26987 EVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNI 27046
Query: 1135 EVKVI 1139
++ I
Sbjct: 27047 HIRSI 27051
Score = 48.9 bits (115), Expect = 3e-05
Identities = 59/283 (20%), Positives = 97/283 (34%), Gaps = 70/283 (24%)
Query: 854 GEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQV 913
GE+V L G P P +TW ++ +I+
Sbjct: 911 GESVTLECHISGYPSPTVTWYREDYQIE-------------------------------- 938
Query: 914 KVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADK 973
+SID QI + G +++ E ++ T + + G + + Y +
Sbjct: 939 --------SSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ--- 987
Query: 974 KSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIY 1033
V E + + + +TE E + F E+ + D ++T+E A Y
Sbjct: 988 -------VSEEFEKETTAVTEKFTTEE---KRFVESRDVVMTDTSLTEEQAGPGEPAAPY 1037
Query: 1034 KNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRY 1093
T+P+V + G + C V GNPKP + W K+ V + RY
Sbjct: 1038 --------------FITKPVVQKL-VEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRY 1082
Query: 1094 RMFSNQ--GVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKL 1134
++ N+ G C L I D G Y N G L
Sbjct: 1083 KVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125
Score = 48.9 bits (115), Expect = 3e-05
Identities = 86/372 (23%), Positives = 145/372 (38%), Gaps = 68/372 (18%)
Query: 784 VANKDLIDKTKFTITGLPTDAKIFVRV---KAVNAAGASE-PKYYSQPILVKEIIEPPKI 839
V +DL+ K ++G+P + ++ +++ +A+ AA ASE P +S+ + E +E +
Sbjct: 4134 VQGRDLLSKESL-LSGIPEEQRLNLKIQICRALQAAVASEQPGLFSEWLRNIEKVEVEAV 4192
Query: 840 RI---PRHLKQTYI----RRVGEAVNLVIPFQGKPRPELTWKKDGA--EIDKNQINIRNS 890
I PRH+ Y+ + V E V ++I L + A I +I+I +
Sbjct: 4193 NITQEPRHIMCMYLVTSAKSVTEEVTIIIEDVDPQMANLKMELRDALCAIIYEEIDILTA 4252
Query: 891 ETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVA- 949
E I K LQ ++D F + ++ ++ E+V NV
Sbjct: 4253 EGPRI--------QQGAKTSLQEEMDSFSGSQKVEPITEPEVESKYLISTEEVSYFNVQS 4304
Query: 950 ----LTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRV 1005
L TP +A+ +D+K E E +S+
Sbjct: 4305 RVKYLDATPVTKGVASAVV------SDEKQDESLKPSEEKEESSSE-------------- 4344
Query: 1006 FSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNAT 1065
G E AT+ + A +G + K + PM PLV+T + G
Sbjct: 4345 -----SGTEEVATVKIQEA----EGGLIKE---------DGPMIHTPLVDTVSEEGDIVH 4386
Query: 1066 LNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDG-GTYCCKAVND 1124
L S+ N K ++ W + D +++ +Q TL I K + D G Y C+A+ND
Sbjct: 4387 LTTSIT-NAK-EVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALND 4444
Query: 1125 LGTVEIECKLEV 1136
G KL V
Sbjct: 4445 SGKTATSAKLTV 4456
Score = 48.1 bits (113), Expect = 5e-05
Identities = 51/213 (23%), Positives = 86/213 (40%), Gaps = 21/213 (9%)
Query: 932 PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSAT 991
P P+ + + + L W P+ +G + I GY I+K ++ V + T++
Sbjct: 8923 PTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSF 8982
Query: 992 ITELVIGNEYY-FRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFT 1050
+ E + ++ Y FRV + N G SE + V+ +D ++ +
Sbjct: 8983 LVENLDEHQMYEFRVKAVNEIGESEPSLPLN---VVIQDDEVPPT----------IKLRL 9029
Query: 1051 QPLVNTYAI-AGYNATLNCSVRGNPKPKITWMKNKVAI------VDDPRYRMFSNQGVCT 1103
+T + AG + V G P PKI W KN+ I + + + ++
Sbjct: 9030 SVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTE 9089
Query: 1104 LEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
L I K D GTY A N LG+V +EV
Sbjct: 9090 LSIPKAVREDKGTYTVTASNRLGSVFRNVHVEV 9122
Score = 47.4 bits (111), Expect = 8e-05
Identities = 28/96 (29%), Positives = 44/96 (45%), Gaps = 2/96 (2%)
Query: 1044 SEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDD--PRYRMFSNQGV 1101
++AP FTQPL + + G AT + G P P+++W ++ I P ++ + G
Sbjct: 3 TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGR 62
Query: 1102 CTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1137
L I + + G Y KA N G +L VK
Sbjct: 63 AKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98
Score = 47.0 bits (110), Expect = 1e-04
Identities = 64/324 (19%), Positives = 119/324 (36%), Gaps = 26/324 (8%)
Query: 835 EPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKN-QINIRNSETD 893
EPP++ + L+ ++ G+ G+P+P+++W K+ + + + +
Sbjct: 3191 EPPQVL--QELQPVTVQS-GKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQE 3247
Query: 894 TIIFIRKAERSHSGKYDLQVKVDKFVET--ASIDIQIIDRPGPPQ---------IVKIED 942
+ + +A + Y + K D V T AS+ +++ + P Q I ++D
Sbjct: 3248 YTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQD 3307
Query: 943 -VWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEY 1001
V E + + ++ Y+ K K S +F + + I E +E
Sbjct: 3308 TVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPS-RFFRMTQFEDTYQLEIAEAYPEDEG 3366
Query: 1002 YFRVFSENMCG-------LSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLV 1054
+ + N G LS + E + + ++ + P F QPL
Sbjct: 3367 TYTFVASNAVGQVSSTANLSLEGFSKFEENTSNSQWHVSLSVSFKKEPLGQKPSFIQPLS 3426
Query: 1055 NTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIV--DDPRYRMFSNQGVCTLEIRKPSPY 1112
+ G + V G PKP+I W N+ I+ D + + G+ + I
Sbjct: 3427 SLRVHNGETVRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHFEESTGMALMLIVDAYSE 3486
Query: 1113 DGGTYCCKAVNDLGTVEIECKLEV 1136
G Y CKA N G L V
Sbjct: 3487 HAGQYSCKAANSAGEATCAATLTV 3510
Score = 46.6 bits (109), Expect = 1e-04
Identities = 36/105 (34%), Positives = 48/105 (45%), Gaps = 4/105 (3%)
Query: 512 LPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSG 571
+PA V + P ++ GL VTVI G + LE ISG P P W R D I E S
Sbjct: 886 VPAPVEIPVTPPTLVSGL---KNVTVIEGESVTLECHISGYPSPTVTWYREDYQI-ESSI 941
Query: 572 RIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKV 616
+ + L+I A +DSG + + NEAG S + V
Sbjct: 942 DFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 986
Score = 46.6 bits (109), Expect = 1e-04
Identities = 29/93 (31%), Positives = 42/93 (45%), Gaps = 3/93 (3%)
Query: 1047 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIV---DDPRYRMFSNQGVCT 1103
P FT PL N A G N ++ +P+P +TW K+ I +D +Y S++G+
Sbjct: 25318 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQ 25377
Query: 1104 LEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
L I + D Y A N G + KL V
Sbjct: 25378 LTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25410
Score = 46.2 bits (108), Expect = 2e-04
Identities = 34/107 (31%), Positives = 47/107 (43%), Gaps = 4/107 (3%)
Query: 1034 KNPVYEDFDFSE----APMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVD 1089
++PVY SE P+F + + N G ATL+ +V G PKPKI W N V +
Sbjct: 3565 ESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTP 3624
Query: 1090 DPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
Y+ + +L I D G Y C A ND G L++
Sbjct: 3625 SADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKI 3671
Score = 46.2 bits (108), Expect = 2e-04
Identities = 25/93 (26%), Positives = 42/93 (45%)
Query: 1046 APMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLE 1105
AP+ + + G+ A C ++ P + W K I + + + S++ + +LE
Sbjct: 4461 APVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLE 4520
Query: 1106 IRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1138
I + D G Y CKA N+ G+V L V V
Sbjct: 4521 ILRTQVVDCGEYTCKASNEYGSVSCTATLTVTV 4553
Score = 45.8 bits (107), Expect = 2e-04
Identities = 30/96 (31%), Positives = 39/96 (40%), Gaps = 3/96 (3%)
Query: 1047 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSN-QGVCTLE 1105
P F + L G A +V G P P +TW K + Y + N G T
Sbjct: 3700 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3759
Query: 1106 IRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVIAQ 1141
+ P D G Y CKA N LG E C E+ V+ +
Sbjct: 3760 VNDPQREDSGLYICKAENMLG--ESTCAAELLVLLE 3793
Score = 45.8 bits (107), Expect = 2e-04
Identities = 29/100 (29%), Positives = 49/100 (49%), Gaps = 5/100 (5%)
Query: 932 PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEH--YHRTS 989
P P + +V ++ +TW P D G IT Y ++K + S W V + + T
Sbjct: 10640 PDAPDQPIVTEVTKDSALVTWNKPHDGGKP-ITNYILEKRETMSKRWARVTKDPIHPYTK 10698
Query: 990 ATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARD 1029
+ +L+ G +Y FRV +EN G+ + + +K V A+D
Sbjct: 10699 FRVPDLLEGCQYEFRVSAENEIGIGDPSPPSK--PVFAKD 10736
Score = 44.7 bits (104), Expect = 5e-04
Identities = 62/284 (21%), Positives = 105/284 (36%), Gaps = 51/284 (17%)
Query: 869 PELT--WKKDGAEID-KNQINIRNSETDTIIFIRKAERSHSGKYDL----QVKVDK-FVE 920
P++T W KD E+ ++I I+ + + I S +GKY + V K FVE
Sbjct: 3038 PDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVE 3097
Query: 921 TASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNA------AITGYTIQKADKK 974
+ I+ I + +++ + + + + +DD +A + +Q+ K
Sbjct: 3098 GRDVRIRSIKK-------EVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHK- 3149
Query: 975 SMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYK 1034
+ V HR + T EY F V N ++ +Y
Sbjct: 3150 ----YVVERRIHRMFISETRQSDAGEYTF-VAGRNRSSVT-----------------LYV 3187
Query: 1035 NPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYR 1094
N E P Q L +G A + G P+PKI+W K + + + +
Sbjct: 3188 NA-------PEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCK 3240
Query: 1095 MFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1138
+ TL + + P D Y C+A ND G L V+V
Sbjct: 3241 FLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEV 3284
Score = 44.3 bits (103), Expect = 7e-04
Identities = 29/98 (29%), Positives = 51/98 (52%), Gaps = 1/98 (1%)
Query: 534 TVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDD 593
++TV G+++RL++ ++G P P + R D A ++ S + D +L+I A +D
Sbjct: 112 SMTVRQGSQVRLQVRVTGIPTPVVKFYR-DGAEIQSSLDFQISQEGDLYSLLIAEAYPED 170
Query: 594 SGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEV 631
SG Y +N N G A ++ ++ V + P T T V
Sbjct: 171 SGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIV 208
Score = 44.3 bits (103), Expect = 7e-04
Identities = 64/320 (20%), Positives = 110/320 (34%), Gaps = 40/320 (12%)
Query: 315 QMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEV-SEDDANVK 373
Q T + +Y E S + F + +T ++ CG+ V S+ A VK
Sbjct: 25981 QKTSERKY------EVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVK 26034
Query: 374 WFKNGEEIIPGPKSRYRIRVEGKKHILIIEGAT-------------KADAAEYSVM-TTG 419
W+ NG E+ K Y G + I++ T K +A++Y+ + TG
Sbjct: 26035 WYHNGVELQESSKIHYT-NTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTG 26093
Query: 420 GQSSAKLSV---DLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDR 476
G + S + P + LT E+ + + K+ +
Sbjct: 26094 GDYTTYASQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESL 26153
Query: 477 LKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVT 536
H + + AL E + TL A++ L ++T
Sbjct: 26154 SSYEHSASAE--MKSAALEEKSLEEKSTTRKIKTTLAARI------------LTKPRSMT 26199
Query: 537 VIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGV 596
V G R GEP P W R + ++ S R + + ST I + D G
Sbjct: 26200 VYEGESARFSCDTDGEPVPTVTWLRKGQ-VLSTSARHQVTTTKYKSTFEISSVQASDEGN 26258
Query: 597 YHINLKNEAGEAHASIKVKV 616
Y + ++N G+ A + +
Sbjct: 26259 YSVVVENSEGKQEAEFTLTI 26278
Score = 43.9 bits (102), Expect = 9e-04
Identities = 94/440 (21%), Positives = 160/440 (36%), Gaps = 71/440 (16%)
Query: 246 REEKKSAAFAKILDPAYQVDKGGRVRFVVELAD-PKLEVKWYKNGQEIRPSTKYIFEHKG 304
++EK+ +P +V +G RF + P+ +V WY NGQ IR S ++ + G
Sbjct: 1789 QKEKQKPDIVLYPEPV-RVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDG 1847
Query: 305 CQRILFINNCQMTDDSEYYVTAG------DEKCSTELFVREP------------------ 340
L I +C+ D E VTA + K E+ RE
Sbjct: 1848 I-HYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRPEFHVH 1906
Query: 341 --------------PIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGE-----EI 381
P+ T+ E ER+ E E + FK E
Sbjct: 1907 EPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEA 1966
Query: 382 IPGPKSRYRIRVEGKKHIL-------------IIEGATKADAAEYSV-MTTGGQSSAKLS 427
I + + R + E + +L + E KA A E + + T +LS
Sbjct: 1967 ITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELS 2026
Query: 428 VDLKPLKILTPLTDQTVNLGKEICLKCEI--SENIPGKWTKNGLPVQESDRLK-VVHKGR 484
++ KI + QTV G + + + + +W KNG+ ++ SDR+ +
Sbjct: 2027 PSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDN 2086
Query: 485 IHKLVIANALTEDEGDYVFAPDAYNVTLPAKVH---VIDPPKIILDGLDADNTVTVIAGN 541
+ +LVI + ED + A N+ H ++ ++I + + V
Sbjct: 2087 VCELVIRDVTAEDSASIMV--KAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDT 2144
Query: 542 KLRLEIPISGEPPPKAMWSRGDKAIMEGSG-RIRTE-SYPDSSTLVIDIAERDDSGVYHI 599
E S EP K W + + EG R+ ++ S L ID ++ +D +
Sbjct: 2145 MATFECETS-EPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLV 2203
Query: 600 NLKNEAGEAHASIKVKVVDF 619
+N A ++ VV+F
Sbjct: 2204 EDENVKTTAKLIVEGAVVEF 2223
Score = 43.9 bits (102), Expect = 9e-04
Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 1/79 (1%)
Query: 1059 IAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYC 1118
+ G A C V G P+PK+ W N I R+R+ G+ L+I YD G
Sbjct: 1807 LEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVK 1865
Query: 1119 CKAVNDLGTVEIECKLEVK 1137
A N G +E + KLE++
Sbjct: 1866 VTAENPEGVIEHKVKLEIQ 1884
Score = 43.9 bits (102), Expect = 9e-04
Identities = 59/286 (20%), Positives = 102/286 (35%), Gaps = 24/286 (8%)
Query: 854 GEAVNLVIPFQGKPRPELTWKKDGAEI-DKNQINIRNSETDTIIFIRKAERSHSGKYDLQ 912
G+ ++ Q KP E+ W +G E+ + ++I+ N+ + I SG Y +
Sbjct: 26016 GQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTY--R 26073
Query: 913 VKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKAD 972
+ AS D +D G E V + P A Y +
Sbjct: 26074 AVCTNYKGEAS-DYATLDVTGGDYTTYASQRRDEEVPRSVFPELTRTEA----YAVSSFK 26128
Query: 973 KKS-MEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGK 1031
K S ME + + + +TE E++ A+ +SA +
Sbjct: 26129 KTSEMEASSSVRE---VKSQMTET-----------RESLSSYEHSASAEMKSAALEEKSL 26174
Query: 1032 IYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDP 1091
K+ + A + T+P T G +A +C G P P +TW++ +
Sbjct: 26175 EEKSTTRKIKTTLAARILTKPRSMT-VYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSA 26233
Query: 1092 RYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1137
R+++ + + T EI D G Y N G E E L ++
Sbjct: 26234 RHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 26279
Score = 43.5 bits (101), Expect = 0.001
Identities = 61/263 (23%), Positives = 104/263 (39%), Gaps = 35/263 (13%)
Query: 261 AYQVDKGGRVRFVVEL-ADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDD 319
+++V G RF++ + + P EVKWY NG E++ S+K + + L I +C TDD
Sbjct: 26010 SHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCH-TDD 26068
Query: 320 SEYY------------------VTAGD-EKCSTELFVREPPIMVTKQLEDTTAYCGERVE 360
S Y VT GD +++ E P V +L T AY +
Sbjct: 26069 SGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPRSVFPELTRTEAYAVSSFK 26128
Query: 361 LECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGG 420
E+ E ++V+ K+ + R + +H + + +A +
Sbjct: 26129 KTSEM-EASSSVREVKS-------QMTETRESLSSYEH----SASAEMKSAALEEKSLEE 26176
Query: 421 QSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEI-SENIPG-KWTKNGLPVQESDRLK 478
+S+ + +ILT TV G+ C+ E +P W + G + S R +
Sbjct: 26177 KSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQ 26236
Query: 479 VVHKGRIHKLVIANALTEDEGDY 501
V I++ DEG+Y
Sbjct: 26237 VTTTKYKSTFEISSVQASDEGNY 26259
Score = 43.1 bits (100), Expect = 0.001
Identities = 41/170 (24%), Positives = 67/170 (39%), Gaps = 16/170 (9%)
Query: 464 WTKNGLPVQESDRLKVVHK-GRIHKLVIANALTEDEGDYVFAPD--------AYNVTLPA 514
W +G + KVV K L+I A D G++ + +T+ A
Sbjct: 1444 WFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEA 1503
Query: 515 KVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGS-GRI 573
H + P + + V + G++L +++ +G P P +W + I+ +I
Sbjct: 1504 VEHQVKPMFV-----EKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKI 1558
Query: 574 RTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKV-VDFPDP 622
R E + L ID DS Y N+AG KV V V+F +P
Sbjct: 1559 RIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEP 1608
Score = 43.1 bits (100), Expect = 0.001
Identities = 67/327 (20%), Positives = 116/327 (35%), Gaps = 65/327 (19%)
Query: 344 VTKQLEDTTAYCGERVELECEVSEDDAN--VKWFKNGEEIIPGPKSRYRIRVEGKKHILI 401
V+ Q+ G V+ C++ D + V W+ ++ K Y I E IL
Sbjct: 25198 VSGQIMHAVGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEK--YEITYEDGVAILY 25255
Query: 402 IEGATKADAAEY--SVMTTGGQSSAKLSVDLK---------------------------- 431
++ TK D Y V+ G+ S+ + +K
Sbjct: 25256 VKDITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLE 25315
Query: 432 -PLKILTPLTDQTVNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVV----HKGR 484
P + PL ++T +G+ + I+ + W K+G ++ D K KG
Sbjct: 25316 RPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKG- 25374
Query: 485 IHKLVIANALTEDEGDYV------FAPDAYNVTLPAKVHVIDPP---------KIILDGL 529
+++L I + T+D+ +Y + D+ L +H PP K +L
Sbjct: 25375 LYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLH--PPPTDSTLRPMFKRLLANA 25432
Query: 530 DADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIA 589
+ G + EI +SG PPP W + + + G D L I
Sbjct: 25433 ECQE------GQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDT 25486
Query: 590 ERDDSGVYHINLKNEAGEAHASIKVKV 616
+D+G Y + N AG ++V
Sbjct: 25487 LPEDTGYYRVTATNTAGSTSCQAHLQV 25513
Score = 42.7 bits (99), Expect = 0.002
Identities = 33/111 (29%), Positives = 46/111 (41%), Gaps = 5/111 (4%)
Query: 1021 KESAVIARDGKI----YKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKP 1076
+E +A +GKI +K E EAP + + + G +A V G P P
Sbjct: 2002 EEKKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDP 2061
Query: 1077 KITWMKNKVAIVDDPR-YRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLG 1126
+ W KN V I R Y + VC L IR + D + KA+N G
Sbjct: 2062 ECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAG 2112
Score = 41.2 bits (95), Expect = 0.006
Identities = 31/101 (30%), Positives = 45/101 (44%), Gaps = 7/101 (6%)
Query: 1022 ESAVIARDGKIYKNPVYEDFDFSEAPM-FTQPLVNTYAIAGYNATLNCSVRGNPKPKITW 1080
E + A+D K + N + E P+ FT+PL + G A L C V K+ W
Sbjct: 5892 EVQLTAKDFKTHANLFVK-----EPPVEFTKPLEDQTVEEGATAVLECEV-SRENAKVKW 5945
Query: 1081 MKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKA 1121
KN I+ +Y + ++ V L I +P D TY C A
Sbjct: 5946 FKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDA 5986
Score = 40.4 bits (93), Expect = 0.010
Identities = 73/318 (22%), Positives = 115/318 (36%), Gaps = 33/318 (10%)
Query: 831 KEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQ-GKPRPELTWKKDGAEIDKNQINIRN 889
K +E +RI K+ +V E V+ F+ + + W KDG EI+
Sbjct: 3093 KLFVEGRDVRIRSIKKEV---QVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHK 3149
Query: 890 SETDTII---FIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGE 946
+ I FI + +S +G+Y ++ T ++ P PPQ+++ E
Sbjct: 3150 YVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTL-----YVNAPEPPQVLQ------E 3198
Query: 947 NVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEY---YF 1003
+T K A+ I + + W+ E T L G EY
Sbjct: 3199 LQPVTVQSGKPARFCAV----ISGRPQPKISWYKE-EQLLSTGFKCKFLHDGQEYTLLLI 3253
Query: 1004 RVFSENM----CGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI 1059
F E+ C D + SA ++ + +P E + P PL +T
Sbjct: 3254 EAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYP--PAIITPLQDTVTS 3311
Query: 1060 AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCC 1119
G A C V G K++W I +RM + LEI + P D GTY
Sbjct: 3312 EGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTF 3370
Query: 1120 KAVNDLGTVEIECKLEVK 1137
A N +G V L ++
Sbjct: 3371 VASNAVGQVSSTANLSLE 3388
Score = 40.0 bits (92), Expect = 0.013
Identities = 44/211 (20%), Positives = 95/211 (45%), Gaps = 28/211 (13%)
Query: 245 RREEKKSAAFAKILDPAYQVD-------KGGRVRFVVELAD-PKLEVKWYKNGQEIRP-- 294
R EE + ++ P + + +G RF +++ P E W+ +GQ+I
Sbjct: 1396 RLEETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDY 1455
Query: 295 STKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFV--------REPPIMVTK 346
+ K + + G Q ++ + +D E+ V A + + + V + M +
Sbjct: 1456 THKVVIKEDGTQSLIIVP-ATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVE 1514
Query: 347 QLEDTTAYCGERVELECEVSED-DANVKWFKNGEEIIPGPKSRY-RIRVEGKK--HILII 402
+L++ G R+E++ + + + ++ W KN + I+P +Y +IR+EG K L I
Sbjct: 1515 KLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVP---HKYPKIRIEGTKGEAALKI 1571
Query: 403 EGATKADAAEY--SVMTTGGQSSAKLSVDLK 431
+ D+A Y + + G+ + + V+++
Sbjct: 1572 DSTVSQDSAWYTATAINKAGRDTTRCKVNVE 1602
Score = 40.0 bits (92), Expect = 0.013
Identities = 96/465 (20%), Positives = 165/465 (35%), Gaps = 92/465 (19%)
Query: 20 EEPSKEKEAGTTPAKDWTLVETPPGEEQAKQNANSQLSILFIEKPQGGTVKVGEDITFIA 79
E S + + + K L E E+ + + L+ + KP+ TV GE F
Sbjct: 26151 ESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSC 26210
Query: 80 KVKAEDLLRKPTIKWF-KGKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAG 138
E + PT+ W KG+ + S + +H ++ TFE+ ++A D G
Sbjct: 26211 DTDGEPV---PTVTWLRKGQ---VLSTSARHQVTTTKYKS-----TFEISSVQASDE--G 26257
Query: 139 NYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRRE 198
NY V + F L + ++ T + K S E + + E + +
Sbjct: 26258 NYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVK-SPEPRVKSPE----AVKSPKR 26312
Query: 199 VKQQEEEPQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKIL 258
VK E V KP+ EK+ + K + ++ E K A
Sbjct: 26313 VKSPEPSHPKAVSP--TETKPTPTEKVQH----LPVSAPPKITQFLKAEASKEIA----- 26361
Query: 259 DPAYQVDKGGRVRFVVELADPKL-EVKWYKNGQEIRPSTKYIFEHKGCQRI-LFINNCQM 316
++ VVE + + EV WYK+G++++ + + F + L INN
Sbjct: 26362 ----------KLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTE 26411
Query: 317 TDDSEYY---------------------------------VTAGDEKCSTELFVR--EP- 340
+D EY D+K + R EP
Sbjct: 26412 SDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPK 26471
Query: 341 --------PIMVTKQLEDTTAYCGERVELECEVS-EDDANVKWFKNGEEIIPGPKSRYRI 391
P++VT L+DTT + + + E W K+G+ I G K Y++
Sbjct: 26472 APEPISSKPVIVT-GLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGK--YKL 26528
Query: 392 RVEGKKHILIIEGATKADAAEY--SVMTTGGQSSAKLSVDLKPLK 434
+ L I +D+ Y +V + G S+ + +K +K
Sbjct: 26529 SEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIK 26573
Score = 39.7 bits (91), Expect = 0.017
Identities = 25/98 (25%), Positives = 37/98 (37%)
Query: 1039 EDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSN 1098
+ F AP T + + G N +V+ P ++ W N V + + + +
Sbjct: 25994 QPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNT 26053
Query: 1099 QGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
GV TLEI D GTY N G L+V
Sbjct: 26054 SGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDV 26091
Score = 39.3 bits (90), Expect = 0.022
Identities = 58/327 (17%), Positives = 107/327 (32%), Gaps = 45/327 (13%)
Query: 854 GEAVNLVIPFQGKPRPELTWKKDGAEIDKN---QINIRNSETDTIIFIRKAERSHSGKYD 910
G+ + G+P PE W DG +I + ++ I+ T ++I + A S SG++
Sbjct: 1425 GQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIV-PATPSDSGEWT 1483
Query: 911 L--QVKVDKFVETASIDIQIIDRPGPPQIV----------------KIEDVWGENVALTW 952
+ Q + + + + ++ ++ P V K+ N + W
Sbjct: 1484 VVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVW 1543
Query: 953 TPPKD------------DGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNE 1000
D +G I + W+T ++ T + E
Sbjct: 1544 LKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATA-INKAGRDTTRCKVNVE 1602
Query: 1001 YYFR--------VFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQP 1052
F + E A E + + ++ D + + P F +
Sbjct: 1603 VEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKK 1662
Query: 1053 LVNTYAIAGYNATLNCSVR--GNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPS 1110
L + A C + G+P + W+ + + R RM + G C+L+
Sbjct: 1663 LTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAY 1722
Query: 1111 PYDGGTYCCKAVNDLGTVEIECKLEVK 1137
D G C+A N GT L VK
Sbjct: 1723 SRDSGIITCRATNKYGTDHTSATLIVK 1749
Score = 38.9 bits (89), Expect = 0.028
Identities = 44/162 (27%), Positives = 69/162 (42%), Gaps = 13/162 (8%)
Query: 279 PKLEVKWYKNGQEIRPST--KYIFEHKGCQRILFINNCQMTDDSEYYVTA----GDEKCS 332
P EV W+++GQ I ST + L I + Y + A G +
Sbjct: 33 PVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKATNGSGQATST 92
Query: 333 TELFVR---EPPIMVTKQLEDTTAYCGERVELECEVSE-DDANVKWFKNGEEIIPGPKSR 388
EL V+ PP V ++L+ T G +V L+ V+ VK++++G EI
Sbjct: 93 AELLVKAETAPPNFV-QRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEI--QSSLD 149
Query: 389 YRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDL 430
++I EG + L+I A D+ YSV T A + +L
Sbjct: 150 FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAEL 191
Score = 38.5 bits (88), Expect = 0.037
Identities = 75/342 (21%), Positives = 130/342 (38%), Gaps = 50/342 (14%)
Query: 316 MTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDA-NVKW 374
MTD S AG + + F+ +P +V K +E G V C+V + +V W
Sbjct: 1018 MTDTSLTEEQAGPGEPAAPYFITKP--VVQKLVE------GGSVVFGCQVGGNPKPHVYW 1069
Query: 375 FKNGEEIIPGPKSRYRIRVEGKKHI----LIIEGATKADAAEYSVMTTG--GQSSAKLSV 428
K+G + G YR +V K L+I DA EY+++ G++SA S+
Sbjct: 1070 KKSGVPLTTG----YRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125
Query: 429 DLKPLKILTPLTDQTVNLGKEICL---KCEISENIPGKWTKNGLPVQESDRLKVVHKGRI 485
+ L + Q + ++ + ++ E PG + + + ++ K
Sbjct: 1126 LEEADYELLMKSQQEMLYQTQVTAFVQEPKVGETAPG-FVYSEYEKEYEKEQALIRKKMA 1184
Query: 486 HKLVIANALTEDEGDYVFAPDA----------YNVTLPAKVHVIDPPKIILD-------- 527
V+ ED+ ++ + + TL + K+ +D
Sbjct: 1185 KDTVVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVE 1244
Query: 528 -GLDAD-NTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS-STL 584
G D+ ++ G + +SG P PK W + K I G R + + D ++L
Sbjct: 1245 SGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGE-RYQMDFLQDGRASL 1303
Query: 585 VIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAP 626
I + +D G+Y N G A S K+ V P AP
Sbjct: 1304 RIPVVLPEDEGIYTAFASNIKGNAICSGKLYV-----EPAAP 1340
Score = 38.1 bits (87), Expect = 0.048
Identities = 38/173 (21%), Positives = 68/173 (39%), Gaps = 11/173 (6%)
Query: 337 VREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGK 396
++E M+ L DT + G+ V L ++ +F+N +++P + +++ +
Sbjct: 4363 IKEDGPMIHTPLVDTVSEEGDIVHLTTSITNAKEVNWYFEN--KLVPSDE-KFKCLQDQN 4419
Query: 397 KHILIIEGATKAD-AAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVN-----LGKEI 450
+ L+I+ D EY S L +K P+ + + LG
Sbjct: 4420 TYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLA 4479
Query: 451 CLKCEISE--NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 501
CEI N+ +W K G + ESD+ + I L I D G+Y
Sbjct: 4480 KFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEY 4532
Score = 38.1 bits (87), Expect = 0.048
Identities = 27/98 (27%), Positives = 41/98 (41%), Gaps = 3/98 (3%)
Query: 1042 DFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGV 1101
D + PMF + L N G + V G P P + W K+ + P + ++G+
Sbjct: 25418 DSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEII-HEGL 25476
Query: 1102 --CTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1137
L IR P D G Y A N G+ + L+V+
Sbjct: 25477 DYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 25514
Score = 37.7 bits (86), Expect = 0.063
Identities = 26/83 (31%), Positives = 34/83 (40%), Gaps = 5/83 (6%)
Query: 264 VDKGGRVRFVVELAD-PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 322
V G VRF + P KW +G EI+ Y E +L I NC D EY
Sbjct: 11150 VKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEY 11209
Query: 323 YVT----AGDEKCSTELFVREPP 341
+T AG + + L V + P
Sbjct: 11210 QITVSNAAGSKTVAVHLTVLDVP 11232
Score = 37.7 bits (86), Expect = 0.063
Identities = 19/65 (29%), Positives = 31/65 (47%)
Query: 1077 KITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
++TW + + +Y + GV L ++ + D GTY CK VND G +L V
Sbjct: 25227 QVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFV 25286
Query: 1137 KVIAQ 1141
K + +
Sbjct: 25287 KGVRE 25291
Score = 37.0 bits (84), Expect = 0.11
Identities = 25/94 (26%), Positives = 40/94 (42%), Gaps = 1/94 (1%)
Query: 1047 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYR-MFSNQGVCTLE 1105
P+F V+ + G A + V G P P+ W + IV+D ++ + G +L
Sbjct: 1411 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLI 1470
Query: 1106 IRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVI 1139
I +P D G + A N G I L V+ +
Sbjct: 1471 IVPATPSDSGEWTVVAQNRAGRSSISVILTVEAV 1504
Score = 36.6 bits (83), Expect = 0.14
Identities = 53/275 (19%), Positives = 95/275 (34%), Gaps = 51/275 (18%)
Query: 340 PPIMVTKQLEDTTAYCGERVELECEVSE-DDANVKWFKNGEEIIPGPKSRYRIRVEGKKH 398
PP +V+ L++ T GE V LEC +S V W++ +I ++I +
Sbjct: 896 PPTLVSG-LKNVTVIEGESVTLECHISGYPSPTVTWYREDYQI--ESSIDFQITFQSGIA 952
Query: 399 ILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISE 458
L+I A D+ + T VN + C ++
Sbjct: 953 RLMIREAFAEDSGRF--------------------------TCSAVNEAGTVSTSCYLAV 986
Query: 459 NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIAN-ALTEDEGDYVFAPDAYNVTLPAKVH 517
+ ++ K V E + +V+ + +LTE++ Y +T P
Sbjct: 987 QVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQK 1046
Query: 518 VIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSG-RIRTE 576
+++ G + + G P P W + + G ++
Sbjct: 1047 LVE-------------------GGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYN 1087
Query: 577 SYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHAS 611
LVI + DD+G Y I ++N+ GE AS
Sbjct: 1088 KQTGECKLVISMTFADDAGEYTIVVRNKHGETSAS 1122
Score = 36.2 bits (82), Expect = 0.18
Identities = 45/250 (18%), Positives = 92/250 (36%), Gaps = 31/250 (12%)
Query: 873 WKKDGAEIDKN-QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDR 931
W KDG EI + + +I+ I+ I+KA+ G+Y DK +++ ++I
Sbjct: 5322 WFKDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKV 5381
Query: 932 PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSAT 991
P V++ + + + P G + G + T++
Sbjct: 5382 EKPLYGVEVFVGETAHFEIELSEPDVHGQWKLKGQPL-------------------TASP 5422
Query: 992 ITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQ 1051
E++ + + + G++ + + +A A + K+ + P+ +F
Sbjct: 5423 DCEIIEDGKKHILILHNCQLGMTGEVSFQAANAKSAANLKVKELPL----------IFIT 5472
Query: 1052 PLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSP 1111
PL + A C V PK W+K I D R+ + + ++ I+ +
Sbjct: 5473 PLSDVKVFEKDEAKFECEVSREPK-TFRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAF 5531
Query: 1112 YDGGTYCCKA 1121
D Y +A
Sbjct: 5532 EDEAKYMFEA 5541
Score = 36.2 bits (82), Expect = 0.18
Identities = 39/146 (26%), Positives = 56/146 (38%), Gaps = 11/146 (7%)
Query: 276 LADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTEL 335
L PK V W K Q ++ + + FE IL IN C +D Y +TA +
Sbjct: 14718 LGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARN------- 14770
Query: 336 FVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEG 395
V E ++T Q+ D ++ + EVS D W E P S Y + +
Sbjct: 14771 IVGEVGDVITIQVHDIPGPPTGPIKFD-EVSSDFVTFSW-DPPENDGGVPISNYVVEMRQ 14828
Query: 396 KKHILIIEGATKADAAEYSV--MTTG 419
+E AT Y +TTG
Sbjct: 14829 TDSTTWVELATTVIRTTYKATRLTTG 14854
Score = 35.8 bits (81), Expect = 0.24
Identities = 25/91 (27%), Positives = 42/91 (46%), Gaps = 1/91 (1%)
Query: 534 TVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS-STLVIDIAERD 592
+V V+ G+ E ISG P P+ W R + I + S+ D + L I +
Sbjct: 14 SVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKA 73
Query: 593 DSGVYHINLKNEAGEAHASIKVKVVDFPDPP 623
+SG Y + N +G+A ++ ++ V PP
Sbjct: 74 NSGRYSLKATNGSGQATSTAELLVKAETAPP 104
Score = 35.8 bits (81), Expect = 0.24
Identities = 23/89 (25%), Positives = 34/89 (38%), Gaps = 2/89 (2%)
Query: 536 TVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSG--RIRTESYPDSSTLVIDIAERDD 593
T G +R + I+ P P W + + I G + ES L I+ DD
Sbjct: 25328 TAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDD 25387
Query: 594 SGVYHINLKNEAGEAHASIKVKVVDFPDP 622
Y + +N+ GE K+ V P P
Sbjct: 25388 DAEYTVVARNKYGEDSCKAKLTVTLHPPP 25416
Score = 35.0 bits (79), Expect = 0.41
Identities = 23/91 (25%), Positives = 37/91 (40%)
Query: 1047 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEI 1106
P F Q L + G L V G P P + + ++ I +++ + +L I
Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLI 163
Query: 1107 RKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1137
+ P D GTY A N +G +L V+
Sbjct: 164 AEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 35.0 bits (79), Expect = 0.41
Identities = 27/90 (30%), Positives = 39/90 (43%), Gaps = 4/90 (4%)
Query: 1047 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEI 1106
P FT L + A+ TL C V + K W K+ IV P+Y + ++ L+I
Sbjct: 5291 PYFTVKLHDKTAVEKDEITLKCEVSKDVPVK--WFKDGEEIVPSPKYSIKADGLRRILKI 5348
Query: 1107 RKPSPYDGGTYCCKAVND--LGTVEIECKL 1134
+K D G Y C D V +E +L
Sbjct: 5349 KKADLKDKGEYVCDCGTDKTKANVTVEARL 5378
Score = 33.9 bits (76), Expect = 0.91
Identities = 27/119 (22%), Positives = 51/119 (42%), Gaps = 11/119 (9%)
Query: 393 VEGKKHILIIEGATKADAAEYSVM-------TTGGQSSAKLSVDLKPLKILTPLTDQTVN 445
VE KK + + T + V+ T + A + + + P +++ L + TV
Sbjct: 850 VEVKKEVGVSITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVI 909
Query: 446 LGKEICLKCEISENIPGK---WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 501
G+ + L+C IS P W + ++ S ++ + I +L+I A ED G +
Sbjct: 910 EGESVTLECHIS-GYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRF 967
Score = 33.5 bits (75), Expect = 1.2
Identities = 35/140 (25%), Positives = 63/140 (45%), Gaps = 11/140 (7%)
Query: 792 KTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIR 851
+ K TI + +KA N +G + + +LVK PP + L+ +R
Sbjct: 62 RAKLTIPAVTKANSGRYSLKATNGSGQATS---TAELLVKAETAPPNF--VQRLQSMTVR 116
Query: 852 RVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTI--IFIRKAERSHSGKY 909
+ G V L + G P P + + +DGAEI ++ ++ + S+ + + I +A SG Y
Sbjct: 117 Q-GSQVRLQVRVTGIPTPVVKFYRDGAEI-QSSLDFQISQEGDLYSLLIAEAYPEDSGTY 174
Query: 910 DLQV--KVDKFVETASIDIQ 927
+ V + TA + +Q
Sbjct: 175 SVNATNSVGRATSTAELLVQ 194
Score = 33.5 bits (75), Expect = 1.2
Identities = 105/543 (19%), Positives = 203/543 (37%), Gaps = 71/543 (13%)
Query: 3 EPTKKEENEVP-APAPPPEEPSKEKEAGTTPAKDWTLVETPPGEEQAKQNANSQLSILFI 61
+P K EE P P PPE PS E +L + P K + S+++ +I
Sbjct: 23940 KPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRP-----KDDGGSRVTGYYI 23994
Query: 62 EKPQGGTVK-VGEDITFIAKVKAEDLLRKPTIKWF------KGKWMDLASKAGKHLQLKE 114
E+ + T K V + T I P ++ + S A + + K+
Sbjct: 23995 ERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKD 24054
Query: 115 TFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSA 174
F++ S+ E+ I DS + E E G +
Sbjct: 24055 PFDKPSQPGELEILSISK------------------DSVTLQWEKPECDGGKEILGYWVE 24096
Query: 175 FKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLKNAKPSEYEKIAF---QYGI 231
+++SG+ ++ K++ ++ Q + LL+ +EYE F + G+
Sbjct: 24097 YRQSGDSAW------------KKSNKERIKDKQFTIGGLLE---ATEYEFRVFAENETGL 24141
Query: 232 TDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQE 291
+ R +K + ++ D ++ + ++ + + P ++KWY+ G+E
Sbjct: 24142 SRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQI-VGRPLPDIKWYRFGKE 24200
Query: 292 IRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTA----GDEKCSTELFVREPPIMVT-- 345
+ S KY G L + + D+ Y A G+ + S++L ++ P
Sbjct: 24201 LIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGY 24260
Query: 346 KQLEDTTAYCGERVELE-CEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEG 404
E G + L + + WF +G++++ ++ E H+++
Sbjct: 24261 PLKEKYYGAVGSTLRLHVMYIGRPVPAMTWF-HGQKLLQNSENITIENTEHYTHLVMKNV 24319
Query: 405 ATKADAAEYSVMTTG--GQSSAKLSVDL--KPLKILTPLTDQTVNLGKEICLKCEISENI 460
K A +Y V + G A L V++ KP K P+ + + L + + +
Sbjct: 24320 QRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEAL-LKNSAVISWKPPADD 24378
Query: 461 PGKWTKNGL----PVQESDRLKVVHKG-RIHKLVIANALTEDEGDY--VFAPDAYNVTLP 513
G W N + +E ++V + I N LTE+ G Y V A + + ++ P
Sbjct: 24379 GGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVN-LTENAGYYFRVSAQNTFGISDP 24437
Query: 514 AKV 516
+V
Sbjct: 24438 LEV 24440
Score = 33.5 bits (75), Expect = 1.2
Identities = 43/147 (29%), Positives = 59/147 (40%), Gaps = 10/147 (6%)
Query: 279 PKLEVKWYKNGQE-IRPSTKY-IFEHKGCQRILFINNCQMTDDSEYYVTA----GDEKCS 332
PK VKWY+ G+E I KY I E KG L I + D + Y V A G +
Sbjct: 24583 PKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGT 24642
Query: 333 TELFVREP-PIMVTKQLED---TTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSR 388
L V P I + K LE A GE V ++ S V ++ G+++I
Sbjct: 24643 ASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHY 24702
Query: 389 YRIRVEGKKHILIIEGATKADAAEYSV 415
I ++ G + DA Y V
Sbjct: 24703 QVIVTRSFTSLVFPNGVERKDAGFYVV 24729
Score = 33.1 bits (74), Expect = 1.5
Identities = 21/96 (21%), Positives = 41/96 (42%), Gaps = 3/96 (3%)
Query: 847 QTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ---INIRNSETDTIIFIRKAER 903
Q+ + G G P PE++W +DG I + + I S+ + I +
Sbjct: 13 QSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTK 72
Query: 904 SHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVK 939
++SG+Y L+ T++ ++ + PP V+
Sbjct: 73 ANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQ 108
Score = 33.1 bits (74), Expect = 1.5
Identities = 21/93 (22%), Positives = 39/93 (41%), Gaps = 1/93 (1%)
Query: 538 IAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVY 597
+ G R ++ + G P P+ W + I+ + +L+I A DSG +
Sbjct: 1423 LEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEW 1482
Query: 598 HINLKNEAGEAHASIKVKVVDFPDPPVAPTVTE 630
+ +N AG + S+ + V+ + V P E
Sbjct: 1483 TVVAQNRAGRSSISV-ILTVEAVEHQVKPMFVE 1514
Score = 33.1 bits (74), Expect = 1.5
Identities = 19/61 (31%), Positives = 27/61 (44%), Gaps = 1/61 (1%)
Query: 1064 ATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVN 1123
AT C P K+ W K+ + + + +YRM S++ V L I D Y C V
Sbjct: 2146 ATFECET-SEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVE 2204
Query: 1124 D 1124
D
Sbjct: 2205 D 2205
Score = 32.3 bits (72), Expect = 2.6
Identities = 28/116 (24%), Positives = 51/116 (43%), Gaps = 8/116 (6%)
Query: 105 KAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTG 164
KAG+ + + S Y ++I++ + G Y C+ + + SC+ L V
Sbjct: 4497 KAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV----- 4551
Query: 165 TTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLKNAKPS 220
T P + + E E+ +L++R +EEEP+V+ +L K KP+
Sbjct: 4552 TVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKR---PEEEEPKVEPKKLEKVKKPA 4604
Score = 32.3 bits (72), Expect = 2.6
Identities = 27/117 (23%), Positives = 42/117 (35%), Gaps = 9/117 (7%)
Query: 1004 RVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYN 1063
R+ N C L ++A + E G + E +FT+ L N
Sbjct: 6056 RILVINKCLLDDEAEYSCEVRTARTSGMLTV--------LEEEAVFTKNLANIEVSETDT 6107
Query: 1064 ATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCK 1120
L C V P ++ W K I++ RY + + L I+ D G Y C+
Sbjct: 6108 IKLVCEV-SKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNCR 6163
Score = 32.3 bits (72), Expect = 2.6
Identities = 16/45 (35%), Positives = 22/45 (48%), Gaps = 3/45 (6%)
Query: 836 PPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI 880
PP+ +P + K Y VGE V + P P +TW K G +I
Sbjct: 25317 PPEFTLPLYNKTAY---VGENVRFGVTITVHPEPHVTWYKSGQKI 25358
Score = 32.0 bits (71), Expect = 3.4
Identities = 27/97 (27%), Positives = 39/97 (40%), Gaps = 5/97 (5%)
Query: 249 KKSAAFAKILDPAYQVDKGGRVRFVVELAD-PKLEVKWYKNGQEIRPSTKYIFEHKGCQR 307
K++A K +V G +F E+ P + +W+K G+EI S K
Sbjct: 4458 KRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYIS 4517
Query: 308 ILFINNCQMTDDSEYYVTAGDE----KCSTELFVREP 340
L I Q+ D EY A +E C+ L V P
Sbjct: 4518 SLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVP 4554
Score = 31.6 bits (70), Expect = 4.5
Identities = 26/88 (29%), Positives = 33/88 (37%), Gaps = 4/88 (4%)
Query: 1052 PLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSP 1111
PL + I G A L C V + W N I D R + L I +
Sbjct: 2404 PLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHA 2463
Query: 1112 YDGGTYCCKAVNDLGTVEIECKLEVKVI 1139
D G Y K + +G VE C L V+ I
Sbjct: 2464 SDEGPY--KLI--VGRVETNCNLSVEKI 2487
Score = 31.2 bits (69), Expect = 5.9
Identities = 15/66 (22%), Positives = 30/66 (45%), Gaps = 1/66 (1%)
Query: 262 YQVDKGGRVRFVVE-LADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDS 320
Y + G ++ + + P+ + W K+G+ ++ +T+ E +L I D
Sbjct: 17949 YSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFG 18008
Query: 321 EYYVTA 326
+Y VTA
Sbjct: 18009 KYTVTA 18014
>gi|110349715 titin isoform N2-B [Homo sapiens]
Length = 26926
Score = 288 bits (738), Expect = 2e-77
Identities = 218/774 (28%), Positives = 346/774 (44%), Gaps = 70/774 (9%)
Query: 272 FVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKC 331
F +L+ K VKWY+NG+EI+ KY FE G L I +C++ D+ EY D K
Sbjct: 6345 FSCQLSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYACGVEDRKS 6404
Query: 332 STELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRI 391
LFV E P+ + + +D G V E+++D V+W +N ++ G K +++
Sbjct: 6405 RARLFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQWLRNNMVVVQGDK--HQM 6462
Query: 392 RVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEIC 451
EGK H L I D EY + ++ AKL + P KI T D V++GK +
Sbjct: 6463 MSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLELAAAP-KIKTADQDLVVDVGKPLT 6521
Query: 452 LKC--EISENIPGKWTKNGLPV----------QESDRL---KVVHKGRIHKLVIANALTE 496
+ + +W K P+ Q S R+ K KGR +K+V+ N +
Sbjct: 6522 MVVPYDAYPKAEAEWFKENEPLSTKTIDTTAEQTSFRILEAKKGDKGR-YKIVLQNKHGK 6580
Query: 497 DEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPK 556
EG + VID P + + + T T L E P++
Sbjct: 6581 AEGFI-------------NLKVIDVPGPVRN---LEVTETFDGEVSLAWEEPLTDGGSKI 6624
Query: 557 AMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG-----EAHAS 611
+ + I + + T+ V + + ++ ++ +N G E
Sbjct: 6625 IGYVVERRDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNP 6684
Query: 612 IKVKV-VDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLN 670
++ + D P PP+ T+T+V + WEPP YDGG+ I Y IE + K S RW
Sbjct: 6685 VEARSKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAM 6744
Query: 671 FDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV----PLAVTSPPTLLTV 726
++ + ++EG Y R+ A N IG+ KPS + PFV P+ SPP LT
Sbjct: 6745 TVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAAT-PFVKVADPIERPSPPVNLTS 6803
Query: 727 DSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVAN 786
T ++V ++W PP G + + GY++E C EG ++WI N
Sbjct: 6804 SDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGK------------------DNWIRCN 6845
Query: 787 KDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLK 846
L+ + + +TGL K RV A N AG S+P P+ + P + + K
Sbjct: 6846 MKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSA-FK 6904
Query: 847 QTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDK-NQINIRNSETDTIIFIRKAERSH 905
V + +++P G PRP TW ++ +++ ++ + I +ERS
Sbjct: 6905 DGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSD 6964
Query: 906 SGKYDLQVKVDKFVETAS--IDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAI 963
G Y L K++ V+T S ID+ +I RP P+ +K D+ ++V LTW PP DDG + +
Sbjct: 6965 KGIYTL--KLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPL 7022
Query: 964 TGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDA 1017
TGY ++K + W V++ T+ +LV G EY F+V + N CG E A
Sbjct: 7023 TGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 7076
Score = 278 bits (711), Expect = 2e-74
Identities = 166/521 (31%), Positives = 269/521 (51%), Gaps = 35/521 (6%)
Query: 511 TLPAKVHV---IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIM 567
TLP V I+PP+I LD D V + A LRL + I G P P+ W + + +
Sbjct: 18594 TLPGSVVAQERIEPPEIELDA-DLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILT 18652
Query: 568 EGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT 627
+ R + E + LVID R DSG Y++ L+N +G A + V+V+D P PV T
Sbjct: 18653 D---RAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLT 18709
Query: 628 VTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEG 687
+ EV D ++WEPP DGG+ I Y +E+++ + + + C +TTF + + EG
Sbjct: 18710 IREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNN-CTKTTFRIENLQEG 18768
Query: 688 VAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAA 747
+Y R+ A N GI P+ + P PP +T+ VT T T++W P+ G +
Sbjct: 18769 CSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGS 18828
Query: 748 GLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIF 807
+ GYV+E +GS E W + + + TI+GL +
Sbjct: 18829 KITGYVVEMQTKGS------------------EKWSTCTQ--VKTLEATISGLTAGEEYV 18868
Query: 808 VRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKP 867
RV AVN G S+P+ P++ ++I P + +P H T+ + E + + +PF+G+P
Sbjct: 18869 FRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFH---TFNVKAREQLKIDVPFKGRP 18925
Query: 868 RPELTWKKDGAEI-DKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDI 926
+ + W+KDG + + ++N+ +S+T T + I++A + G Y+L V T I I
Sbjct: 18926 QATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITI 18985
Query: 927 QIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYH 986
++DRPGPP ++I++V +++ ++W PP+ DG I+ Y ++K + S W V +
Sbjct: 18986 IVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVA 19045
Query: 987 RTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIA 1027
RTS I L G+EY FRV +EN G S + ++ SAV+A
Sbjct: 19046 RTSIKIVRLTTGSEYQFRVCAENRYGKS---SYSESSAVVA 19083
Score = 270 bits (691), Expect = 4e-72
Identities = 179/588 (30%), Positives = 288/588 (48%), Gaps = 53/588 (9%)
Query: 438 PLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQ------ESDRLKVVHKGRIHKLVIA 491
P+ D + I KC++S G+WT P E ++L H+ I
Sbjct: 16364 PIYDGGCEIQGYIVEKCDVSV---GEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAIN 16420
Query: 492 NALTEDEGDYVFAPDAYNVTLPAKVHV---IDPPKIILDGLDADNTVTVIAGNKLRLEIP 548
A + D +P + V ++ P I LD L+ + + AG LRL +P
Sbjct: 16421 KAGVGEHAD-----------VPGPIIVEEKLEAPDIDLD-LELRKIINIRAGGSLRLFVP 16468
Query: 549 ISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEA 608
I G P P+ W + D I + + T S+ ++LV+D R DSG Y + L+N +G
Sbjct: 16469 IKGRPTPEVKWGKVDGEIRDAAIIDVTSSF---TSLVLDNVNRYDSGKYTLTLENSSGTK 16525
Query: 609 HASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMR 668
A + V+V+D P PPV VTE+ D + WEPP DGGS I Y +E+++ +
Sbjct: 16526 SAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAA 16585
Query: 669 LNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDS 728
+ + C + +++ ++ EG +Y R+ A N GI P+ + P V PP +TVD
Sbjct: 16586 VVTN-CHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDD 16644
Query: 729 VTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKD 788
VT +V++ W P+H G + + Y++E AK S++ E A
Sbjct: 16645 VTRNSVSLSWTKPEHDGGSKIIQYIVE------MQAKHSEKWSECA-------------- 16684
Query: 789 LIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQT 848
+ + IT L + RV AVN G S+P+ + PI+ K+++ P + + +
Sbjct: 16685 RVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDV---KPAFSS 16741
Query: 849 YIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDK-NQINIRNSETDTIIFIRKAERSHSG 907
Y +VG+ + + +P G+P+P +TW KDG + + +IN+ +S T + I++ + G
Sbjct: 16742 YSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGG 16801
Query: 908 KYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWGENVALTWTPPKDDGNAAITGY 966
+Y + V +TASI+I +D+P PP+ VK +DV E++ L+W PP G IT Y
Sbjct: 16802 QYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNY 16861
Query: 967 TIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLS 1014
+QK D + W V RT+ +T+L G EY FR+F+EN G S
Sbjct: 16862 IVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQS 16909
Score = 259 bits (662), Expect = 1e-68
Identities = 158/580 (27%), Positives = 280/580 (48%), Gaps = 37/580 (6%)
Query: 519 IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESY 578
++ P++ LD + + V AG R+ IP G P P+ WSR + E + +++ E
Sbjct: 17522 LEAPELDLDS-ELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEG---EFTDKVQIEKG 17577
Query: 579 PDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIM 638
+ + L ID +R+D+G Y + L+N +G A + VKV+D P PP V EV D +
Sbjct: 17578 VNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFL 17637
Query: 639 NWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVN 698
WEPP DGG+ + Y I++++ + ++ C +T+F+ + + EG Y R+ A N
Sbjct: 17638 VWEPPIIDGGAKVKNYVIDKRESTRKAYANVS-SKCSKTSFKVENLTEGAIYYFRVMAEN 17696
Query: 699 AIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCF 758
G+ P SPP +T+ V+ T+ ++ W P+H G + + GYV+E
Sbjct: 17697 EFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQP 17756
Query: 759 EGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGA 818
+G+ E W + + + +TGL + + RVKA N G
Sbjct: 17757 KGT------------------EKWSIVAESKV--CNAVVTGLSSGQEYQFRVKAYNEKGK 17796
Query: 819 SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGA 878
S+P+ P++ K++ P +++P + TY + GE + + IP G+PRP ++W KDG
Sbjct: 17797 SDPRVLGVPVIAKDLTIQPSLKLPFN---TYSIQAGEDLKIEIPVIGRPRPNISWVKDGE 17853
Query: 879 EIDK-NQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPP-Q 936
+ + ++N+ + T T++ I++ + GKY + T ++ + ++++PGPP
Sbjct: 17854 PLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVG 17913
Query: 937 IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELV 996
V+ ++V + V ++W PP G I+ Y ++K D + W V RT+ IT+L
Sbjct: 17914 PVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTIKITKLK 17973
Query: 997 IGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNT 1056
G EY FR+F+EN G S A + ++ ++ +K P F + Q LV
Sbjct: 17974 TGTEYQFRIFAENRYGKS--APLDSKAVIVQYP---FKEPGPPGTPFVTSISKDQMLVQW 18028
Query: 1057 YAIAGYNAT--LNCSVRGNPKPKITWMKNKVAIVDDPRYR 1094
+ T + + K I W+K + D +++
Sbjct: 18029 HEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFK 18068
Score = 248 bits (632), Expect = 3e-65
Identities = 149/496 (30%), Positives = 252/496 (50%), Gaps = 30/496 (6%)
Query: 521 PPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPD 580
PP+I LD D VT+ A LRL +PI G P P+ W+R ++ + T SY
Sbjct: 15360 PPEIELDA-DLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESLDKASIESTSSY-- 15416
Query: 581 SSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNW 640
+ L++ R DSG Y + ++N +G A + V+V+D P PP V EV + W
Sbjct: 15417 -TLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTW 15475
Query: 641 EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAI 700
+PP DGGS I Y +E+++ + + + C +T+++ ++ EG +Y R+ A N
Sbjct: 15476 DPPLLDGGSKIKNYIVEKRESTRKAYSTVATN-CHKTSWKVDQLQEGCSYYFRVLAENEY 15534
Query: 701 GISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEG 760
GI P+ + PP +T+ VT +V++ W P+H G + + GY++E +G
Sbjct: 15535 GIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKG 15594
Query: 761 STSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASE 820
S + W A + T+ TITGL + RV A N G S+
Sbjct: 15595 S------------------DKW--ATCATVKVTEATITGLIQGEEYSFRVSAQNEKGISD 15634
Query: 821 PKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI 880
P+ S P++ K+++ PP ++ L T+ GE + + +PF G+P P +TW KD +
Sbjct: 15635 PRQLSVPVIAKDLVIPPAFKL---LFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPL 15691
Query: 881 DK-NQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IV 938
+ ++N ++E ++++ I+ A R G Y +++ ++++ ++D+PGPP V
Sbjct: 15692 KQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPV 15751
Query: 939 KIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIG 998
K+++V +++ L+W PPK DG ++I Y ++K D + W V RT+ L G
Sbjct: 15752 KMDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVSATVARTTIKACRLKTG 15811
Query: 999 NEYYFRVFSENMCGLS 1014
EY FR+ +EN G S
Sbjct: 15812 CEYQFRIAAENRYGKS 15827
Score = 244 bits (624), Expect = 3e-64
Identities = 156/511 (30%), Positives = 243/511 (47%), Gaps = 35/511 (6%)
Query: 518 VIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRG--DKAIMEGSGRIRT 575
+++PP+I LD V V AG +RL + G P PK W + D + +G +
Sbjct: 12103 ILEPPEIDLDA-SMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKG----QV 12157
Query: 576 ESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDW 635
+ + LVI + RDDSG Y + L N AGE + V+V+D P P V++V
Sbjct: 12158 DLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTS 12217
Query: 636 CIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIF 695
C ++W PP DGGS + Y +E+++ W + ++ K+T+F ++ G Y R+
Sbjct: 12218 CHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEV-KKTSFHVTNLVPGNEYYFRVT 12276
Query: 696 AVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGY 752
AVN G P+ +P + PL+ PP L V +T + T+ W PP G A +DGY
Sbjct: 12277 AVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGY 12336
Query: 753 VLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKA 812
+ Y E + PA+ W ++ +TGL K RV A
Sbjct: 12337 ITSYREE----------------EQPADRW--TEYSVVKDLSLVVTGLKEGKKYKFRVAA 12378
Query: 813 VNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELT 872
NA G S P+ KE + PPKI +P + + G+ + + GKP P
Sbjct: 12379 RNAVGVSLPREAEGVYEAKEQLLPPKILMPEQI----TIKAGKKLRIEAHVYGKPHPTCK 12434
Query: 873 WKKDGAE-IDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDR 931
WKK E + + + + +++ +I+ I+ R SG Y L + +T I + ++D
Sbjct: 12435 WKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDA 12494
Query: 932 PGPPQ-IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSA 990
PGPPQ I D+ + +L+W P +DG + IT Y ++K D +W T + +TS
Sbjct: 12495 PGPPQPPFDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSC 12554
Query: 991 TITELVIGNEYYFRVFSENMCGLSEDATMTK 1021
+ +L+ G EY FRV +EN G+SE T K
Sbjct: 12555 RVGKLIPGQEYIFRVRAENRFGISEPLTSPK 12585
Score = 244 bits (623), Expect = 3e-64
Identities = 143/488 (29%), Positives = 242/488 (49%), Gaps = 34/488 (6%)
Query: 534 TVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSS----TLVIDIA 589
T+ V AG + +P G P P +WS+ D + RT +Y D++ +L I+ A
Sbjct: 19698 TLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDL-------RTRAYVDTTDSRTSLTIENA 19750
Query: 590 ERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGS 649
R+DSG Y + ++N A ++ VKV+D P PP TV +V + +++W+ P DGG+
Sbjct: 19751 NRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGA 19810
Query: 650 PILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPS 709
P+ Y IE+++ W+ + + C +++ + EG Y R+ N G+ P+
Sbjct: 19811 PVKNYHIEKREASKKAWVSVT-NNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETK 19869
Query: 710 RPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDE 769
SPP L V S++ +V++ W P+H G + + YV+E +G
Sbjct: 19870 EGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQ-------- 19921
Query: 770 NGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPIL 829
++W+ + T ++GL +++ F RV A N AG S+P+ P+L
Sbjct: 19922 ----------KNWVKC--AVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVL 19969
Query: 830 VKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKN-QINIR 888
+KE +EPP+I + T R G + + IP GKP P++T +DG + + N
Sbjct: 19970 IKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTE 20029
Query: 889 NSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWGEN 947
+ + I ++++ + +G+Y++ A I+I ++DRPGPP V I D+ E+
Sbjct: 20030 ITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDITEES 20089
Query: 948 VALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFS 1007
V L W PPK DG + +T Y + K + + W V RT + +L G EY FR+ +
Sbjct: 20090 VTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKA 20149
Query: 1008 ENMCGLSE 1015
EN G+S+
Sbjct: 20150 ENRFGISD 20157
Score = 244 bits (622), Expect = 4e-64
Identities = 157/500 (31%), Positives = 254/500 (50%), Gaps = 31/500 (6%)
Query: 522 PKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS 581
P + LD D V V AG +R+ +SG+PPP W+ ++ + + + E+ S
Sbjct: 10025 PDLQLDASVRDRIV-VHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEA---TIETTAIS 10080
Query: 582 STLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTE-VGDDWCIMNW 640
S++VI +R GVY + KNEAGE +I V V+D P P P + + ++ C + W
Sbjct: 10081 SSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTW 10140
Query: 641 EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAI 700
P DGGSPI Y IE+++ W + + + ++ + +I+G AY RI A N+I
Sbjct: 10141 FSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNA-TVQGLIQGKAYFFRIAAENSI 10199
Query: 701 GISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 757
G+ S V P+ V P L V VT TVT+ W PP + G + + YVLE
Sbjct: 10200 GMGPFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESR 10259
Query: 758 FEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAG 817
G+ + V N +L+ + K+T+ GL RV AVN G
Sbjct: 10260 LIGTEKFHK-----------------VTNDNLLSR-KYTVKGLKEGDTYEYRVSAVNIVG 10301
Query: 818 ASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDG 877
+P + ++PI K+ + PP + + K T RVGEA L + GKP+P+++W KD
Sbjct: 10302 QGKPSFCTKPITCKDELAPPTLHLDFRDKLTI--RVGEAFALTGRYSGKPKPKVSWFKDE 10359
Query: 878 AEI-DKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ 936
A++ + ++ +I+ + + KA+RS SGKY + V+ + ++DRPGPP
Sbjct: 10360 ADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPV 10419
Query: 937 -IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITEL 995
V ++V + + ++W PP DDG + IT Y I+K + W V +T+ +++L
Sbjct: 10420 GPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKL 10479
Query: 996 VIGNEYYFRVFSENMCGLSE 1015
+ G +Y FR+ +EN+ G+S+
Sbjct: 10480 LEGKDYIFRIHAENLYGISD 10499
Score = 239 bits (611), Expect = 8e-63
Identities = 151/488 (30%), Positives = 240/488 (49%), Gaps = 28/488 (5%)
Query: 530 DADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIA 589
D TVT+ AG LRL + +SG PPP WS+ + + TESY S L++D
Sbjct: 22954 DLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESY---SLLIVDKV 23010
Query: 590 ERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGS 649
R D+G Y I +N++G+ A++ VKV D P P + V EV D + WE P DGG+
Sbjct: 23011 NRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGA 23070
Query: 650 PILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPS 709
P+ Y +E K++ + R + C +T + ++EG Y R+ N GI +P S
Sbjct: 23071 PVNNYIVE-KREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETS 23129
Query: 710 RPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDE 769
+ V P L V VT +TVT+ W P + G + L GYVLE C G+
Sbjct: 23130 DAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGT-------- 23181
Query: 770 NGEAAYDLPAEDW--IVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQP 827
E W +V K + + T+T L + R++A N G SEP+
Sbjct: 23182 ----------ERWMKVVTLKPTV--LEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTA 23229
Query: 828 ILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI-DKNQIN 886
+ V+++ P I + ++T G V LVIP G+P P +W G+++ + ++
Sbjct: 23230 VTVQDLRVLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVT 23289
Query: 887 IRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWG 945
+ + IR+ +G+Y L++K + +I + I+D+PGPP +KI+++
Sbjct: 23290 VETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDA 23349
Query: 946 ENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRV 1005
++ ++W PP+ DG A ++GY +++ D W V E R++ T L GNEY FRV
Sbjct: 23350 TSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRV 23409
Query: 1006 FSENMCGL 1013
+ N G+
Sbjct: 23410 AATNRFGI 23417
Score = 239 bits (610), Expect = 1e-62
Identities = 152/526 (28%), Positives = 245/526 (46%), Gaps = 40/526 (7%)
Query: 508 YNVTLPAKVHVIDPPKIILDGLDADNT--------------VTVIAGNKLRLEIPISGEP 553
Y V+ K V DP +I L L AD+ + VI N + + +P +G P
Sbjct: 6867 YRVSAENKAGVSDPSEI-LGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYP 6925
Query: 554 PPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIK 613
P A W GDK ++E R++ ++ + LVI +ER D G+Y + L+N I
Sbjct: 6926 RPTATWCFGDK-VLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEID 6984
Query: 614 VKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDL 673
V V+ P P ++ D + WEPP DGGSP+ GY +E+++ W ++ D
Sbjct: 6985 VNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKV-MDF 7043
Query: 674 CKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPF---VPLAVTSPPTLLTVDSVT 730
+ F +++G Y ++ A N G +P+ P P V PP + T
Sbjct: 7044 VTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRT 7103
Query: 731 DTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLI 790
++ + W PP + G + + GY++E C GS + W+ + +
Sbjct: 7104 ANSIFLTWDPPKNDGGSRIKGYIVERCPRGS------------------DKWVACGEP-V 7144
Query: 791 DKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYI 850
+TK +TGL RVKA+N GAS+P ++ I + E P+I + L
Sbjct: 7145 AETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLT 7204
Query: 851 RRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKN-QINIRNSETDTIIFIRKAERSHSGKY 909
+ G + L GKP P++TW K + ++ +I I N + + I ++RS +G Y
Sbjct: 7205 VKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTY 7264
Query: 910 DLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQ 969
++ TA +++ ++D+PGPP I DV E+ LTW PP+DDG + IT Y ++
Sbjct: 7265 IIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVE 7324
Query: 970 KADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1015
+ S W + T+ T+L+ EY FRV +ENM G+ E
Sbjct: 7325 RRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGE 7370
Score = 239 bits (610), Expect = 1e-62
Identities = 138/399 (34%), Positives = 201/399 (50%), Gaps = 21/399 (5%)
Query: 620 PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTF 679
P PP P VT V D ++W P DGGSPILGY +ERK++ W ++ L F
Sbjct: 14762 PGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIF 14821
Query: 680 EPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWR 739
+ + +G+AYE R+ A N G SKPS PS P + L PP ++T TVT++W
Sbjct: 14822 KSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWA 14881
Query: 740 PPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITG 799
P++ G + Y++E DLP W+ AN I + +FT++G
Sbjct: 14882 KPEYTGGFKITSYIVE------------------KRDLPNGRWLKANFSNILENEFTVSG 14923
Query: 800 LPTDAKIFVRVKAVNAAGA-SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVN 858
L DA RV A NAAGA S P S I ++ +E PKI++ K T I + GEA
Sbjct: 14924 LTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVILKAGEAFR 14983
Query: 859 LVIPFQGKPRPELTWKKDGAEIDKN-QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDK 917
L G+P P + W KDG E++ ++ I+ ++ T + + + R SG Y L
Sbjct: 14984 LEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPG 15043
Query: 918 FVETASIDIQIIDRPGPPQ-IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSM 976
+++++DRPGPP+ + + +V E L+W PP DDG A I Y +QK + +
Sbjct: 15044 GFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRL 15103
Query: 977 EWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1015
W V T +T+L+ GNEY FRV + N G+ E
Sbjct: 15104 AWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGE 15142
Score = 239 bits (610), Expect = 1e-62
Identities = 162/609 (26%), Positives = 285/609 (46%), Gaps = 58/609 (9%)
Query: 429 DLKPLKILTPLTDQTVNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIH 486
D+KP + +V +G+++ ++ IS WTK+GLP++++ R+ V +
Sbjct: 16734 DVKPA-----FSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLT 16788
Query: 487 KLVIANALTEDEGDYVFAPDAYNVTLPAKVHVI-----DPPK--IILDGLDADNTVTVIA 539
L I +D G Y A + ++ DPPK + D + A++
Sbjct: 16789 TLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAES------ 16842
Query: 540 GNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRT-----ESYPDSSTLVIDIAERDDS 594
I +S PP + I++ T + +TL + +
Sbjct: 16843 -------ITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTE 16895
Query: 595 GVYHINLKNEAGEAHASIKVKVV-----DFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGS 649
+ I +N G++ A +V P PP P T + D ++ W P +GGS
Sbjct: 16896 YQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGS 16955
Query: 650 PILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPS 709
P++GY +ERK++ S W ++N + +T F+ + + EG+ YE R++A N +G+ K S S
Sbjct: 16956 PVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNS 17015
Query: 710 RPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDE 769
+V PP V +T++W P + G + + GY++E
Sbjct: 17016 ECYVARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVE-------------- 17061
Query: 770 NGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGA-SEPKYYSQPI 828
DLP W+ A+ + +T+FT++GL D + RV A NAAGA S+P + PI
Sbjct: 17062 ----KRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPI 17117
Query: 829 LVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKN-QINI 887
K+ +E P+I + + T + GE L GKP P + W + EI+++ + I
Sbjct: 17118 TAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEI 17177
Query: 888 RNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWGE 946
+N++ ++ ++ A R G+Y L+ ++ ++++++DRPGPP+ V++ V E
Sbjct: 17178 KNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSE 17237
Query: 947 NVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVF 1006
+LTW+PP DG + I+ Y ++K + + W V S +T+L+ GNEY FR+
Sbjct: 17238 KCSLTWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIM 17297
Query: 1007 SENMCGLSE 1015
+ N G+ E
Sbjct: 17298 AVNKYGVGE 17306
Score = 239 bits (610), Expect = 1e-62
Identities = 171/602 (28%), Positives = 283/602 (47%), Gaps = 51/602 (8%)
Query: 436 LTPLTDQTVNL--GKEICLKCEISENIP--GKWTKNGLPVQESDRLKVVHKGRIHKLVIA 491
L+ + +T+++ G+ + L I+ P W G ++ES+R+ V ++ KL I
Sbjct: 23243 LSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIR 23302
Query: 492 NALTEDEGDYVFAPDAYNVTLPA----KVHVIDPP-----KIILDGLDADNTVTVIAGNK 542
D G+Y + NVT KV ++D P I +D +DA + +
Sbjct: 23303 ETTIRDTGEYTL--ELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPE 23360
Query: 543 LRLEIPISG-----EPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVY 597
L P+SG + W +++ + + + + + R G Y
Sbjct: 23361 LDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSY 23420
Query: 598 HINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIE 657
L++E E +SI++ P PP + +V D + W PP DGGS + GY +E
Sbjct: 23421 ---LQSEVIECRSSIRI-----PGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVE 23472
Query: 658 RKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAV 717
RK+ ++ RW+R+N T + + EG+ YE R+ A+NA G KPS PS+P V +
Sbjct: 23473 RKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDP 23532
Query: 718 TSPPTLLTVDSVTDTT---VTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAA 774
+PP VTDTT V++ W P+ G + + GY++E ++ D++
Sbjct: 23533 IAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIE--------MQKVDQH---- 23580
Query: 775 YDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEII 834
+W N ++T+T LP A+ RV A NA G EP + V E++
Sbjct: 23581 ------EWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEML 23634
Query: 835 EPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDT 894
E P + ++ R G + L IP +GKP P W K+G +I K + I SET T
Sbjct: 23635 EYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAM-IATSETHT 23693
Query: 895 IIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWGENVALTWT 953
+ I++A+R SG YDL ++ + I +++I P P+ ++ +D+ +V ++W
Sbjct: 23694 ELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVSWR 23753
Query: 954 PPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL 1013
PP DDG A I GY +++ + W+T+ TS + L EY+FRV +EN G+
Sbjct: 23754 PPADDGGADILGYILERREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGI 23813
Query: 1014 SE 1015
S+
Sbjct: 23814 SK 23815
Score = 238 bits (607), Expect = 2e-62
Identities = 169/578 (29%), Positives = 277/578 (47%), Gaps = 44/578 (7%)
Query: 464 WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVH--VIDP 521
W K+G+ ++E R +++ L + + + D G YV T V+ V+D
Sbjct: 19326 WAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDK 19385
Query: 522 P-----KIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTE 576
P + ++GL A+ + I K S I EG ++
Sbjct: 19386 PGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQM--- 19442
Query: 577 SYPDSSTLVIDIAERDDSGVYHINLKNE--AGEAHASIKVKVVD---FPDPPVAPTVTEV 631
+S V + + ++ ++ + N+ GE S+ +K +D P PP + +T V
Sbjct: 19443 ----TSCKVTKLLKGNEY-IFRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSV 19497
Query: 632 GDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYE 691
+ + W P DGGS I GY IER++K S RW+R+N + + + EG YE
Sbjct: 19498 TKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYE 19557
Query: 692 VRIFAVNAIGISKPSMPS---RPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAG 748
R++A NA G+S PS S R P+ + SPP+ + TT+T+ W P G A
Sbjct: 19558 YRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAP 19617
Query: 749 LDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFV 808
+ GY +EY K+SD+ DW + + L T++TI+GL T A+
Sbjct: 19618 ITGYTVEY--------KKSDDT----------DWKTSIQSLRG-TEYTISGLTTGAEYVF 19658
Query: 809 RVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPR 868
RVK+VN GAS+P S P + KE E P I +++T I + G + + +PF+G+P
Sbjct: 19659 RVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPV 19718
Query: 869 PELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQI 928
P + W K ++ + + + +++ T + I A R+ SGKY L ++ + ++ +++
Sbjct: 19719 PNVLWSKPDTDL-RTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKV 19777
Query: 929 IDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRT 988
+D PGPP + ++DV E+ L+W P++DG A + Y I+K + W +V + +R
Sbjct: 19778 LDTPGPPTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCNRL 19837
Query: 989 SATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVI 1026
S +T L G YYFRV EN G+ A TKE I
Sbjct: 19838 SYKVTNLQEGAIYYFRVSGENEFGVGIPAE-TKEGVKI 19874
Score = 236 bits (603), Expect = 7e-62
Identities = 153/533 (28%), Positives = 261/533 (48%), Gaps = 43/533 (8%)
Query: 518 VIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTES 577
++ PP+ LD D T+ + AG +RL +P+ G PPPK WS+ + + + G + +S
Sbjct: 13190 ILIPPEGELDA-DLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIG-LDIKS 13247
Query: 578 YPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCI 637
+ L + + D+G Y + L+N G+ +I VKV+D P PPV TV E+ D
Sbjct: 13248 TDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAY 13307
Query: 638 MNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAV 697
+ WEPP DGGSPI+ Y ++++ + W + + C +T+F + EG +Y R+FA
Sbjct: 13308 VTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTE-CSKTSFRVANLEEGKSYFFRVFAE 13366
Query: 698 NAIGISKPSMPSRPFVPLAVTSPPTL-LTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEY 756
N GI P +R V + T P + L V SV+ ++ ++ W+ P G + + GYV+++
Sbjct: 13367 NEYGIGDPG-ETRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDF 13425
Query: 757 CFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAA 816
++EN W K L +++ L + RV A N
Sbjct: 13426 L---------TEEN----------KWQRVMKSL--SLQYSAKDLTEGKEYTFRVSAENEN 13464
Query: 817 GASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKK- 875
G P + ++ ++ + P + + Y+ + L IP +GKP P ++WKK
Sbjct: 13465 GEGTPSEIT--VVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKG 13522
Query: 876 DGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPG-P 934
+ ++++ +S +T + + ++S +GKY + +K + +I I+++ +PG P
Sbjct: 13523 EDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKPGIP 13582
Query: 935 PQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITE 994
+K ++V E + L W PPKDDG + IT Y ++K D + +W T +T+ +T
Sbjct: 13583 TGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAVQKTTFRVTR 13642
Query: 995 LVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAP 1047
L G EY FRV +EN G+ E K ++AR FD +AP
Sbjct: 13643 LHEGMEYTFRVSAENKYGVGEG---LKSEPIVAR----------HPFDVPDAP 13682
Score = 236 bits (603), Expect = 7e-62
Identities = 185/698 (26%), Positives = 312/698 (44%), Gaps = 80/698 (11%)
Query: 364 EVSEDDANVKWFK----NGEEII-------PGPKSRYRIRVEGKKHILIIEGATKADAAE 412
+VS+ A++ W K G ++ P ++ I E K ++ G + +
Sbjct: 17726 DVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQ 17785
Query: 413 YSVMTTG--GQSSAKL--------SVDLKPLKILTPLTDQTVNLGKEICLKCEI----SE 458
+ V G+S ++ + ++P + P ++ G+++ ++ +
Sbjct: 17786 FRVKAYNEKGKSDPRVLGVPVIAKDLTIQP-SLKLPFNTYSIQAGEDLKIEIPVIGRPRP 17844
Query: 459 NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAP--DAYNVTLPAKV 516
NI W K+G P++++ R+ V L I +D G Y A T V
Sbjct: 17845 NI--SWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSV 17902
Query: 517 HVIDPP-----KIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSG 571
V++ P + D + AD V IS EPP + I+E
Sbjct: 17903 IVLEKPGPPVGPVRFDEVSADFVV-------------ISWEPPAYTGGCQISNYIVEKRD 17949
Query: 572 RIRTESYPDSSTLV---IDIAERDDSGVYHINL--KNEAGE-AHASIKVKVVDFP----D 621
T + S+T+ I I + Y + +N G+ A K +V +P
Sbjct: 17950 TTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEPG 18009
Query: 622 PPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEP 681
PP P VT + D ++ W P DGG+ I+GY +E+K+K S W++LN ++T F+
Sbjct: 18010 PPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKT 18069
Query: 682 KKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPP 741
+ EG+ YE ++ A N +GI KPS S FV PP +T VT++W+ P
Sbjct: 18070 TGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIVITRNNVTLKWKKP 18129
Query: 742 DHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLP 801
+ G + + GY++E DLP W+ A+ + +T+FT++GL
Sbjct: 18130 AYDGGSKITGYIVE------------------KKDLPDGRWMKASFTNVLETEFTVSGLV 18171
Query: 802 TDAKIFVRVKAVNAAG-ASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLV 860
D + RV A NAAG SEP S I ++ I+ P + K + GE L
Sbjct: 18172 EDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGETFVLE 18231
Query: 861 IPFQGKPRPELTWKKDGAEIDKN--QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKF 918
+GKP P++ W KDG E+++ ++ I+++ T + ++ R+ G+Y L++
Sbjct: 18232 ADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGG 18291
Query: 919 VETASIDIQIIDRPGPPQ-IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSME 977
++ I ++++DRPGPP+ +K+ V E L W PP DG A I+ Y I+K + +
Sbjct: 18292 TKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLS 18351
Query: 978 WFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1015
W V + +T+L+ GNEY FRV + N G+ E
Sbjct: 18352 WTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGE 18389
Score = 234 bits (596), Expect = 5e-61
Identities = 171/604 (28%), Positives = 285/604 (47%), Gaps = 46/604 (7%)
Query: 428 VDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVVHKGRIHK 487
+DLK +LT T+ L E ++ + + K+ + S R+K+ + K
Sbjct: 11706 LDLKLSGVLTVKAGDTIRL--EAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSK 11763
Query: 488 LVIANALTEDEGDYVFAPD--AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRL 545
+ A D G YV A + A V+V+D P G + + ++ ++
Sbjct: 11764 FSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKP-----GPVRNLKIVDVSSDRCT- 11817
Query: 546 EIPISGEPPPKAMWSRGDKAIMEG--SGRIRTESYPDS----STLVIDIAERDDSGVYHI 599
+ +PP I+E + R+ +Y + T V + E ++ ++ +
Sbjct: 11818 ---VCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEY-IFRV 11873
Query: 600 NLKNEAG-----EAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGY 654
+N+ G E+ I D P P P VT+V + + W PP YDGG I GY
Sbjct: 11874 RAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGY 11933
Query: 655 FIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV- 713
F+E+K+K S+RW+ +N E + + ++ Y+ R+ A N IGI +PS+PSRP V
Sbjct: 11934 FLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVA 11993
Query: 714 --PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENG 771
P+ PPT V T ++T+ W P + G A + GYV+E K +D +
Sbjct: 11994 KDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEM------RPKIADAS- 12046
Query: 772 EAAYDLPAEDWIVANKDL-IDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILV 830
P E W N + + +FT+T L + + RV A N G P + I
Sbjct: 12047 ------PDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKP 12100
Query: 831 KEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAE--IDKNQINIR 888
KEI+EPP+I + +++ I R G + L +G+P P++TW+K G + + K Q+++
Sbjct: 12101 KEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDL- 12159
Query: 889 NSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENV 948
+T + I + R SGKY L + + ++++++D PGP +K+ DV +
Sbjct: 12160 -VDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSC 12218
Query: 949 ALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSE 1008
++W PP++DG + +T Y ++K + W TV +TS +T LV GNEYYFRV +
Sbjct: 12219 HVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAV 12278
Query: 1009 NMCG 1012
N G
Sbjct: 12279 NEYG 12282
Score = 233 bits (594), Expect = 8e-61
Identities = 202/725 (27%), Positives = 321/725 (44%), Gaps = 83/725 (11%)
Query: 332 STELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKW----FKNGEEIIP---- 383
S L +REP I V ++ ED +E++ EV+++ + W + G EII
Sbjct: 10208 SEALVIREP-ITVPERPED--------LEVK-EVTKNTVTLTWNPPKYDGGSEIINYVLE 10257
Query: 384 ----GPKSRYRIRVEGK-KHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTP 438
G + +++ + ++G + D EY V K S KP+
Sbjct: 10258 SRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDE 10317
Query: 439 LTDQTVNLGKEICLKCEISE------NIPGK------WTKNGLPVQESDRLKVVHKGRIH 486
L T++L L + E GK W K+ V E DR +
Sbjct: 10318 LAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATL 10377
Query: 487 KLVIANALTEDEGDYVFAPDAYNVTLPAK----VHVIDPPKIILDGLDADNTVTVIAGNK 542
L A D G Y + N T K V+V+D P + + D
Sbjct: 10378 ALEKIKAKRSDSGKYCVVVE--NSTGSRKGFCQVNVVDRPGPPVGPVSFDEVT------- 10428
Query: 543 LRLEIPISGEPPPKAMWSRGDKAIMEGSGRIR------TESYPDSSTLVIDIAERDDSGV 596
+ + IS +PP S+ I+E + T + ++ V + E D +
Sbjct: 10429 -KDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDY-I 10486
Query: 597 YHINLKNEAG--EAHASIKVKVVD---FPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPI 651
+ I+ +N G + S +K D PD P P VTEV D ++ W P +DGG PI
Sbjct: 10487 FRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKP-HDGGKPI 10545
Query: 652 LGYFIERKKKQSSRWMRLNFD-LCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSR 710
Y +E+++ S RW R+ D + T F ++EG YE R+ A N IGI PS PS+
Sbjct: 10546 TNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSK 10605
Query: 711 PFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQS 767
P P+A SPP T +V + W+PP H G + + GY++EY K
Sbjct: 10606 PVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEY-------QKVG 10658
Query: 768 DENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQP 827
DE A P + +TK+ +TGL RV AVNAAG S+P + +P
Sbjct: 10659 DEEWRRANHTP---------ESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEP 10709
Query: 828 ILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINI 887
+LVK+ +EPP++ + ++ + +VG+ + L +G P P++TWKK+ + + I
Sbjct: 10710 VLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAP-TKARI 10768
Query: 888 RNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGEN 947
+ + + IR A G Y L V+ +T S+ + ++D+PGPP+ +++ ++ ++
Sbjct: 10769 DVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDS 10828
Query: 948 VALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFS 1007
LTW P DDG + IT Y +++ D S +W + + S L GN+Y FRV +
Sbjct: 10829 CYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAA 10888
Query: 1008 ENMCG 1012
EN G
Sbjct: 10889 ENQYG 10893
Score = 233 bits (593), Expect = 1e-60
Identities = 172/611 (28%), Positives = 288/611 (47%), Gaps = 45/611 (7%)
Query: 241 LKRMRREEKKSAAFA-------KILDPAYQVDKGGR--VRFVVELADPKLEVKWYKNGQE 291
L R E KSAA +I++P ++ + V F ++ + +KW KNG+E
Sbjct: 6216 LTNHRGENVKSAANLIVEEEDLRIVEPLKDIETMEKKSVTFWCKVNRLNVTLKWTKNGEE 6275
Query: 292 IRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDT 351
+ + + + +L I +C D+ EY VTAG +K EL + E P + LED
Sbjct: 6276 VPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYIVTAGQDKSVAELLIIEAPTEFVEHLEDQ 6335
Query: 352 TAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAA 411
T + C++S + ANVKW++NG EI G K Y+ +G H LII+ D
Sbjct: 6336 TVTEFDDAVFSCQLSREKANVKWYRNGREIKEGKK--YKFEKDGSIHRLIIKDCRLDDEC 6393
Query: 412 EYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLP 470
EY+ +S A+L V+ P++I+ P D G ++ E++ + + +W +N +
Sbjct: 6394 EYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQWLRNNMV 6453
Query: 471 VQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLD 530
V + D+ +++ +G+IH+L I + D+G+Y F A + AK+ + PKI
Sbjct: 6454 VVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFI--AKDKEARAKLELAAAPKI----KT 6507
Query: 531 ADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAE 590
AD + V G L + +P P +A W + ++ + + ++ + ++ I A+
Sbjct: 6508 ADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKT----IDTTAEQTSFRILEAK 6563
Query: 591 RDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSP 650
+ D G Y I L+N+ G+A I +KV+D P P VTE D + WE P DGGS
Sbjct: 6564 KGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSK 6623
Query: 651 ILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIE-GVAYEVRIFAVNAIGISKPSMPS 709
I+GY +ER+ + W+ L D + F + + GV Y R+ A N +G +P
Sbjct: 6624 IIGYVVERRDIKRKTWV-LATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETD 6682
Query: 710 RPFVPLA---VTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQ 766
P + V PP +T+ V V++ W PP++ G A + YV+E TS +
Sbjct: 6683 NPVEARSKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIE--LRDKTSIR- 6739
Query: 767 SDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQ 826
+ A + AED D+++ +++ RV+A N G +P +
Sbjct: 6740 ----WDTAMTVRAEDLSATVTDVVEGQEYSF-----------RVRAQNRIGVGKPSAATP 6784
Query: 827 PILVKEIIEPP 837
+ V + IE P
Sbjct: 6785 FVKVADPIERP 6795
Score = 232 bits (592), Expect = 1e-60
Identities = 158/525 (30%), Positives = 252/525 (48%), Gaps = 40/525 (7%)
Query: 520 DPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWS---RGDKAIMEGSGRI--- 573
+ P++ +D + A + + AG+++R+ I G P PK+ W + KA+ +G I
Sbjct: 9309 EEPEVFID-IGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPED 9367
Query: 574 -RTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVG 632
+ E+ +SS ++I +R +G Y I KN+AG+ A+ +VKV+D P PP V+++
Sbjct: 9368 AQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDIT 9427
Query: 633 DDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEV 692
C ++W+ P DGG I GY IE++ W ++N D C TTF ++ Y
Sbjct: 9428 RGSCRLSWKMPDDDGGDRIKGYVIEKRTIDGKAWTKVNPD-CGSTTFVVPDLLSEQQYFF 9486
Query: 693 RIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGL 749
R+ A N GI P + P+ PP L + +T TV + W+PP + G + +
Sbjct: 9487 RVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPV 9546
Query: 750 DGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVR 809
Y++E T K+ E W NK +++ +FT+ L + R
Sbjct: 9547 THYIVECLAWDPTGTKK-------------EAWRQCNKRDVEELQFTVEDLVEGGEYEFR 9593
Query: 810 VKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRP 869
VKAVNAAG S+P P + PP I LK+ G VN+V +G P P
Sbjct: 9594 VKAVNAAGVSKPSATVGPCDCQRPDMPPSI----DLKEFMEVEEGTNVNIVAKIKGVPFP 9649
Query: 870 ELTW------KKDGAE---IDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVE 920
LTW K D E D + + +T T++ I ++ RS +G Y + +
Sbjct: 9650 TLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLV-IPQSRRSDTGLYTITAVNNLGTA 9708
Query: 921 TASIDIQIIDRPGPP-QIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF 979
+ + + ++ RPGPP +K E V + + L+W PPKDDG + IT Y I+K + W
Sbjct: 9709 SKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWV 9768
Query: 980 TVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESA 1024
V + TI +L+ G+EY FR+ ++N G+ E E+A
Sbjct: 9769 HVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETA 9813
Score = 232 bits (591), Expect = 2e-60
Identities = 174/651 (26%), Positives = 304/651 (46%), Gaps = 60/651 (9%)
Query: 386 KSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVN 445
K++Y+ R + + I + +D +++ LSV +K L TV
Sbjct: 12762 KAQYQFRAIARTAVNISPPSEPSDPV--TILAENVPPRIDLSVAMKSLL--------TVK 12811
Query: 446 LGKEICLKCEI-SENIPG-KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF 503
G +CL + + +P W K+G ++ ++ +K+ + + L + + +D GDY
Sbjct: 12812 AGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTI 12871
Query: 504 APDAYNVTLPA--KVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSR 561
+ + + A K+ V+D P G A + + ++ L S EPP + S
Sbjct: 12872 TAENSSGSKSATIKLKVLDKP-----GPPASVKINKMYSDRAML----SWEPPLEDGGSE 12922
Query: 562 GDKAIMEGSGRIRTESYPDSSTLVI---DIAERDDSGVYHINL--KNEAGEA-----HAS 611
I++ R S+T+ I + + + Y + +N+ G +
Sbjct: 12923 ITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPA 12982
Query: 612 IKVKVVDFP---DPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMR 668
I D P DPPV +T+ D ++W+PPA DGGSPI GY +E+++ Q+ W +
Sbjct: 12983 IAKNPYDPPGRCDPPVISNITK---DHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTK 13039
Query: 669 LNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLT 725
+N E T + + EG YE R+ A+N G KPS S+ P PP
Sbjct: 13040 VNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPK 13099
Query: 726 VDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVA 785
V T ++V++ W P + G + + GY++E K++D + +LP
Sbjct: 13100 VYDTTRSSVSLSWGKPAYDGGSPIIGYLVE--------VKRADSDNWVRCNLPQN----- 13146
Query: 786 NKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHL 845
+ KT+F +TGL D + RV AVN G S+P K+I+ PP+ + L
Sbjct: 13147 ----LQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADL 13202
Query: 846 KQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI-DKNQINIRNSETDTIIFIRKAERS 904
++T I R G + L +P +G+P P++TW K + D+ ++I++++ DT + +
Sbjct: 13203 RKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKY 13262
Query: 905 HSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAIT 964
+GKY L ++ + +I ++++D PGPP V ++++ ++ +TW PP DG + I
Sbjct: 13263 DAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPII 13322
Query: 965 GYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1015
Y +QK D + W TV +TS + L G Y+FRVF+EN G+ +
Sbjct: 13323 NYVVQKRDAERKSWSTVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGD 13373
Score = 229 bits (585), Expect = 9e-60
Identities = 149/513 (29%), Positives = 245/513 (47%), Gaps = 28/513 (5%)
Query: 506 DAYNVTLPAK-VHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDK 564
D+ VT K V + P++ +D + T V AG +RL I G P P A+WS+ D
Sbjct: 21841 DSCEVTGTIKAVDRLTAPELDIDA-NFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDS 21899
Query: 565 AIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPV 624
+ + T+S+ STL ++ R+D+G Y + ++N +G + VKV+D P PP
Sbjct: 21900 NLSLRADIHTTDSF---STLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGPPG 21956
Query: 625 APTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKM 684
T +V + W+ P DGG+ I Y +E+++ W ++ + C F+ +
Sbjct: 21957 PITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVIS-EKCTRQIFKVNDL 22015
Query: 685 IEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHI 744
EGV Y R+ AVN G+ +P P V +PP L V + ++ + W PDH
Sbjct: 22016 AEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHD 22075
Query: 745 GAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDA 804
G + + GY+LE +GS + W+ A + FT+ L
Sbjct: 22076 GGSRITGYLLEMRQKGS------------------DFWVEAGH--TKQLTFTVERLVEKT 22115
Query: 805 KIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQ 864
+ RVKA N AG SEP+ +++KE P + Q + G + +P
Sbjct: 22116 EYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPIS 22175
Query: 865 GKPRPELTWKKDGAEI-DKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETAS 923
G+P P++TWK + + + ++++I ++ T + ++ + R SG+Y L ++ V+T S
Sbjct: 22176 GRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFS 22235
Query: 924 IDIQIIDRPGP-PQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVI 982
+ + +I RPGP +++ V E+ L+W PKD G IT Y ++K + + W V
Sbjct: 22236 VTVVVIGRPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVN 22295
Query: 983 EHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1015
RT +T L EY FRV SEN G+S+
Sbjct: 22296 SSVKRTQIKVTHLTKYMEYSFRVSSENRFGVSK 22328
Score = 229 bits (584), Expect = 1e-59
Identities = 159/586 (27%), Positives = 270/586 (46%), Gaps = 42/586 (7%)
Query: 465 TKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKI 524
+++G+P++ + R + + ++T D G Y + T A ++++
Sbjct: 20014 SRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIV----- 20068
Query: 525 ILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIM---EGSGRIRTESYPDS 581
+LD T V+ + + + EPP S+ I+ E S + TE
Sbjct: 20069 VLDR-PGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATV 20127
Query: 582 STLVIDIAERDDSGVYHINLKNE--------AGEAHASIKVKVVDFPDPPVAPTVTEVGD 633
+ ++ + + Y +K E A ++K+ P PP P VT V
Sbjct: 20128 ARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTT-PGPPSTPWVTNVTR 20186
Query: 634 DWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVR 693
+ + W P +GGS ++GY +E K + S W + N + + T F+ + G+ YE R
Sbjct: 20187 ESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFR 20246
Query: 694 IFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYV 753
++A NA G+ KPS PS P + + PP + + ++ +V++ W+ P G + + GY+
Sbjct: 20247 VYAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYI 20306
Query: 754 LEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAV 813
+E DLP W A+ + +T+F I+GL +++ RV A
Sbjct: 20307 VE------------------RRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFAR 20348
Query: 814 NAAGA-SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELT 872
NA G+ S P PI + P I +P + R G +V L GKP P +
Sbjct: 20349 NAVGSISNPSEVVGPITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIE 20408
Query: 873 WKKDGAEIDKNQINIRNSETD-TIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDR 931
W KD E+ N + + TD I I+ A+R +SG Y+L+++ +A+I +QI+D+
Sbjct: 20409 WYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDK 20468
Query: 932 PGPP-QIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSA 990
PGPP ++ + V E + L W PP DDG A IT Y ++K + + W V EH
Sbjct: 20469 PGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVSEHLEECII 20528
Query: 991 TITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNP 1036
T T+++ GNEY FRV + N G+ E + +V+A++ + P
Sbjct: 20529 TTTKIIKGNEYIFRVRAVNKYGIGEP---LESDSVVAKNAFVTPGP 20571
Score = 228 bits (581), Expect = 3e-59
Identities = 172/638 (26%), Positives = 274/638 (42%), Gaps = 44/638 (6%)
Query: 394 EGKKHILIIEGATKADAAEYSVMTTGGQSSAKL-SVDLKPLKILTPLTDQTVNLGKEICL 452
EGK++ + + S +T + +DLK L L L + N +I +
Sbjct: 13450 EGKEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPI 13509
Query: 453 KCEISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTL 512
K + + ++ W K P+ R+ V L++ + D G Y T
Sbjct: 13510 KGKPAPSV--SWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTK 13567
Query: 513 PA--KVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGS 570
+ V+ P I + D VT A + + PP S I+E
Sbjct: 13568 EGTISIKVVGKPGIPTGPIKFDE-VTAEA-------MTLKWAPPKDDGGSEITNYILEKR 13619
Query: 571 GRIRTE-----SYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVV-----DFP 620
+ + S +T + + ++ +N+ G +V D P
Sbjct: 13620 DSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVP 13679
Query: 621 DPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFE 680
D P P + +V D + W P GGSPI GY +E K++ S W R N + F+
Sbjct: 13680 DAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFK 13739
Query: 681 PKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRP 740
+ EG+ YE R+ A+N G+ KPS+PS P V L PP V ++T +VT+ W
Sbjct: 13740 VTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTE 13799
Query: 741 PDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGL 800
P + G L GY++E DLP++ W+ AN + + FT+T L
Sbjct: 13800 PKYDGGHKLTGYIVE------------------KRDLPSKSWMKANHVNVPECAFTVTDL 13841
Query: 801 PTDAKIFVRVKAVNAAGA-SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNL 859
K R++A N AGA S P ++ I+ K+ E P I + +K + G+ + L
Sbjct: 13842 VEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVL 13901
Query: 860 -VIPFQGKPRPELTWKKDGAEIDKNQI-NIRNSETDTIIFIRKAERSHSGKYDLQVKVDK 917
I GKP P+ +W K G +I + I I ++ T +++ I+ A R +G+Y +
Sbjct: 13902 NAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPF 13961
Query: 918 FVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSME 977
+ + + ++D PGPP V+I +V E LTWTPP +DG + I Y ++K + +
Sbjct: 13962 GTKVEHVKVTVLDVPGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLL 14021
Query: 978 WFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1015
W V E T+L+ GNEY FRV + N G E
Sbjct: 14022 WTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYGKGE 14059
Score = 227 bits (579), Expect = 4e-59
Identities = 156/571 (27%), Positives = 260/571 (45%), Gaps = 50/571 (8%)
Query: 464 WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF--APDAYNVTLPAKVHVIDP 521
W K+G ++E+ R+ V + L I A ED G Y + A ++T+P + V+D
Sbjct: 18931 WRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDR 18990
Query: 522 P----KIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTES 577
P I +D + D+ I IS PP + I+E T
Sbjct: 18991 PGPPGPIRIDEVSCDS-------------ITISWNPPEYDGGCQISNYIVEKKETTSTTW 19037
Query: 578 YPDSSTLV---IDIAERDDSGVYHINL-------KNEAGEAHASIKVKVVDFPDPPVAPT 627
+ S + I I Y + K+ E+ A + P PP P
Sbjct: 19038 HIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPK 19097
Query: 628 VTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEG 687
V ++ W+ P DGGS ++GY +E K++ S W + N L +T + + EG
Sbjct: 19098 VVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIADTQMKVSGLDEG 19157
Query: 688 VAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAA 747
+ YE R++A N GI K S P PP V ++T +V+++W P + G A
Sbjct: 19158 LMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGA 19217
Query: 748 GLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIF 807
+ GY++E +LP W+ N I +T F +T L D +
Sbjct: 19218 KITGYIVE------------------RRELPDGRWLKCNYTNIQETYFEVTELTEDQRYE 19259
Query: 808 VRVKAVNAA-GASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGK 866
RV A NAA SEP + PI+VK+ +EPP++ + + + + GE + + G+
Sbjct: 19260 FRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGR 19319
Query: 867 PRPELTWKKDGAEIDKN-QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASID 925
P P ++W KDG EI++ + I +++ T++ ++ R +G+Y L +K + +++
Sbjct: 19320 PLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVN 19379
Query: 926 IQIIDRPGPPQ-IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEH 984
+++D+PGPP ++I + E +L+W P++DG A I Y ++K + + W
Sbjct: 19380 CKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGE 19439
Query: 985 YHRTSATITELVIGNEYYFRVFSENMCGLSE 1015
TS +T+L+ GNEY FRV N G+ E
Sbjct: 19440 LQMTSCKVTKLLKGNEYIFRVTGVNKYGVGE 19470
Score = 226 bits (575), Expect = 1e-58
Identities = 154/509 (30%), Positives = 238/509 (46%), Gaps = 33/509 (6%)
Query: 519 IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESY 578
++PP++ILD A + G+ LRL I G P PK W + D+ + + R +
Sbjct: 10716 LEPPELILDANMAREQ-HIKVGDTLRLSAIIKGVPFPKVTWKKEDR---DAPTKARIDVT 10771
Query: 579 PDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIM 638
P S L I A +D G+Y + ++N AG S+KV V+D P PP V+E+ D C +
Sbjct: 10772 PVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYL 10831
Query: 639 NWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVN 698
W+ P DGGS I Y +ER+ S++W L+ K++ F K + EG Y R+ A N
Sbjct: 10832 TWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHF-AKHLNEGNQYLFRVAAEN 10890
Query: 699 AIG---ISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLE 755
G + P + PL PP L V T V++ W PD G + + GY++E
Sbjct: 10891 QYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVE 10950
Query: 756 YCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNA 815
Y EG+ +DWI + + +TGL RVKA N
Sbjct: 10951 YQEEGT------------------QDWI--KFKTVTNLECVVTGLQQGKTYRFRVKAENI 10990
Query: 816 AGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKK 875
G P + PI +E + PP + + L + + + G V +G P P W
Sbjct: 10991 VGLGLPD-TTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTT 11049
Query: 876 DGAEIDKNQ-INIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGP 934
DG+EI ++ + +++ I+ R +G+Y + V +T ++ + ++D PGP
Sbjct: 11050 DGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGP 11109
Query: 935 PQ-IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATIT 993
P + I DV E++ ++W PPKDDG + + Y ++K D + W V +T I
Sbjct: 11110 PTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIP 11169
Query: 994 ELVIGNEYYFRVFSENMCGLSE--DATMT 1020
L G EY FRV +EN G+ D+T T
Sbjct: 11170 HLQKGCEYVFRVRAENKIGVGPPLDSTPT 11198
Score = 224 bits (572), Expect = 3e-58
Identities = 142/494 (28%), Positives = 240/494 (48%), Gaps = 29/494 (5%)
Query: 529 LDAD--NTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVI 586
LDA+ T+ V AG +R+ +PI G P P+ W++ + + + TES+ + L+I
Sbjct: 14281 LDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESF---TLLII 14337
Query: 587 DIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYD 646
R D+G + + ++N AG+ + V+V+D P P + T++ D ++W+ P D
Sbjct: 14338 PECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLID 14397
Query: 647 GGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPS 706
GGS I Y +E+++ + C + T++ + EG Y R+ A N GI +P+
Sbjct: 14398 GGSRITNYIVEKREATRKSYSTATTK-CHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPT 14456
Query: 707 MPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQ 766
+ P SPP L + +T +TV++ W P H G + + GYV+E +GS
Sbjct: 14457 ETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGS----- 14511
Query: 767 SDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQ 826
+ W + + + + L + +V AVN+AG S P+ S+
Sbjct: 14512 -------------DQW--THITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPR-ESR 14555
Query: 827 PILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ-I 885
P++VKE P++ + ++ I + G+ + + IP G+P+P +TWKK + + Q +
Sbjct: 14556 PVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRV 14615
Query: 886 NIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVW 944
N + T TI+ I + RS SG Y L + I IQ+ D PGPP +K ++V
Sbjct: 14616 NFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVS 14675
Query: 945 GENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFR 1004
+ V +W PP++DG I+ Y ++ S W + RT+ T L G EY FR
Sbjct: 14676 SDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIRTTYKATRLTTGLEYQFR 14735
Query: 1005 VFSENMCGLSEDAT 1018
V ++N G+ T
Sbjct: 14736 VKAQNRYGVGPGIT 14749
Score = 224 bits (570), Expect = 5e-58
Identities = 165/572 (28%), Positives = 264/572 (46%), Gaps = 51/572 (8%)
Query: 464 WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV--FAPDAYNVTLPAKVHVIDP 521
W K+ +P++++ R+ L I +A ED G YV A V V+D
Sbjct: 15684 WHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDK 15743
Query: 522 P-----KIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTE 576
P + +D + AD+ I +S PP S + I+E T
Sbjct: 15744 PGPPTGPVKMDEVTADS-------------ITLSWGPPKYDGGSSINNYIVEKRDTSTTT 15790
Query: 577 SYPDSSTLVIDI--AERDDSGV---YHINLKNEAGEA-HASIKVKVVDF----PDPPVAP 626
S+T+ A R +G + I +N G++ + + + V + P PP P
Sbjct: 15791 WQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTP 15850
Query: 627 TVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIE 686
VT D + W P DGGS ++GY +ERK++ S W++LN +T F+ + E
Sbjct: 15851 VVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEE 15910
Query: 687 GVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGA 746
GV YE R+ A N +GI KPS S +V PP VT +VT++W+ P + G
Sbjct: 15911 GVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGG 15970
Query: 747 AGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKI 806
+ + GY++E +LP W+ A+ I T F +TGL D +
Sbjct: 15971 SKITGYIVE------------------KKELPEGRWMKASFTNIIDTHFEVTGLVEDHRY 16012
Query: 807 FVRVKAVNAAGA-SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQG 865
RV A NAAG SEP + I ++ ++PP+I + K T + GE+ + G
Sbjct: 16013 EFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYG 16072
Query: 866 KPRPELTWKKDGAEIDKN-QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASI 924
KP P + W K E+ ++ I++++ T + ++ A R SG Y L+ K + ++
Sbjct: 16073 KPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTV 16132
Query: 925 DIQIIDRPGPPQ-IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIE 983
+++++DRPGPP+ V I V E L W PP DG + I Y +++ + + W V
Sbjct: 16133 NVKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDA 16192
Query: 984 HYHRTSATITELVIGNEYYFRVFSENMCGLSE 1015
+ S +T+L+ GNEY FR+ + N G+ E
Sbjct: 16193 NVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGE 16224
Score = 220 bits (560), Expect = 7e-57
Identities = 161/544 (29%), Positives = 248/544 (45%), Gaps = 66/544 (12%)
Query: 520 DPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYP 579
+ P+I LD + +TV AG K+ L ++G+P PK W++ D I++ RI E+ P
Sbjct: 7189 EAPEIFLD-VKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADM-ILKQDKRITIENVP 7246
Query: 580 DSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMN 639
ST+ I ++R D+G Y I N G A A ++V V+D P PP A +T+V ++ C++
Sbjct: 7247 KKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLT 7306
Query: 640 WEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNA 699
W PP DGGS I Y +ER+ S W +L+ K+T F+ K+I Y R+ A N
Sbjct: 7307 WNPPRDDGGSKITNYVVERRATDSEVWHKLS-STVKDTNFKATKLIPNKEYIFRVAAENM 7365
Query: 700 IGISKP--SMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 757
G+ +P + P PPT L +T VT+ W PD G + + GY +E
Sbjct: 7366 YGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVE-- 7423
Query: 758 FEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAG 817
D + W+ NK + T + + GL K RV A N AG
Sbjct: 7424 ----------------RLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAG 7467
Query: 818 ASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKK-- 875
+P ++PIL+K+ I+PP +K GK L W K
Sbjct: 7468 PGKPSKSTEPILIKDPIDPPWPPGKPTVKDV----------------GKTSVRLNWTKPE 7511
Query: 876 --DGAEIDKNQINIRNSETDTIIFIRKAE-----------RSHSGKYDLQVK-VDKFVET 921
GA+I+ I + + TD ++R AE +Y +V+ V+K E+
Sbjct: 7512 HDGGAKIESYVIEMLKTGTDE--WVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGES 7569
Query: 922 ASID-------IQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKK 974
+ + + P PP+ +++ ++ L WT P+ DG + IT Y ++K D +
Sbjct: 7570 EPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVR 7629
Query: 975 SMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYK 1034
W TV T T+T L G+ Y FRV +EN G S+ + E +V+A+D
Sbjct: 7630 RKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEI--EDSVLAKDTFTTP 7687
Query: 1035 NPVY 1038
P Y
Sbjct: 7688 GPPY 7691
Score = 219 bits (559), Expect = 9e-57
Identities = 174/636 (27%), Positives = 290/636 (45%), Gaps = 67/636 (10%)
Query: 428 VDLKPLKILTPLTDQTV-NLGKEICLKCEISENIPG--KWTKNGLPVQESDRLKVVHKGR 484
V+ +K+ D + G+ L+ ++S P +W+K+G ++ + +L++
Sbjct: 14959 VEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADF 15018
Query: 485 IHKLVIANALTEDEGDYV--------FAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVT 536
LV ++ D G Y FA +NV V+D P + VT
Sbjct: 15019 STNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVK------VLDRP----GPPEGPLAVT 15068
Query: 537 VIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIR-----TESYPDSSTLVIDIAER 591
+ K L S PP ++ D I++ R S + L + +
Sbjct: 15069 EVTSEKCVL----SWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLK 15124
Query: 592 DDSGVYHINLKNEAG-----EAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYD 646
+ ++ + N+ G E+ + V PDPP P VT + D ++ W P D
Sbjct: 15125 GNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSD 15184
Query: 647 GGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPS 706
GGS I+ Y +ER+ K RW++ N + ++ + EG YE RI A NA GIS PS
Sbjct: 15185 GGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPS 15244
Query: 707 MPSRPFVPLAVT----SPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGST 762
P+ PF T PP V + +++++ W P + G + + GY++E
Sbjct: 15245 -PTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIA----- 15298
Query: 763 SAKQSDENGEAAYDLPAED-W-IVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASE 820
LP ED W IV + T +TITGL + + +R+ A+N+ G E
Sbjct: 15299 --------------LPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGE 15344
Query: 821 PKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKD-GAE 879
P ++ + PP+I + L++ R + L +P +G+P PE+ W +D G
Sbjct: 15345 PALVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGES 15404
Query: 880 IDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVK 939
+DK +I ++ + T++ + R SGKY L V+ ++A ++++++D PGPPQ +K
Sbjct: 15405 LDK--ASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLK 15462
Query: 940 IEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGN 999
+++V +V LTW PP DG + I Y ++K + + TV + H+TS + +L G
Sbjct: 15463 VKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGC 15522
Query: 1000 EYYFRVFSENMCGL---SEDATMTKESAVIARDGKI 1032
YYFRV +EN G+ +E A K S GKI
Sbjct: 15523 SYYFRVLAENEYGIGLPAETAESVKASERPLPPGKI 15558
Score = 219 bits (557), Expect = 2e-56
Identities = 163/601 (27%), Positives = 258/601 (42%), Gaps = 40/601 (6%)
Query: 430 LKPLKILTPLTDQTVNLGKEICLKCEI--SENIPGKWTKNGLPVQESDRLKVVHKGRIHK 487
L P KIL P T+ GK++ ++ + + KW K V S L V
Sbjct: 12400 LLPPKILMP-EQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSI 12458
Query: 488 LVIANALTEDEGDYVFAPDAYNVTLPAKVHVI-----DPPKIILDGLDADNTVTVIAGNK 542
L+I + +D G Y + + T K+ V+ PP+ D D D
Sbjct: 12459 LIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADAC-----S 12513
Query: 543 LRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLK 602
L IP+ + + G S +S V + + ++ + +
Sbjct: 12514 LSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEY-IFRVRAE 12572
Query: 603 NEAGEAHASIKVKVV-----DFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIE 657
N G + K+V P P VT+V D + W+ P DGGSPI+GY IE
Sbjct: 12573 NRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIE 12632
Query: 658 RKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAV 717
RK++ S W++ N L + T + ++EG+ Y RI+A+N G S PS P+
Sbjct: 12633 RKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMP 12692
Query: 718 TSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDL 777
PP V VT +TV++ W P H G + + GY +E C L
Sbjct: 12693 VDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEAC------------------KL 12734
Query: 778 PAEDWIVAN--KDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIE 835
P + W+ N I + ++T TGL A+ R A A S P S P+ +
Sbjct: 12735 PGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENV 12794
Query: 836 PPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ-INIRNSETDT 894
PP+I + +K + G V L GKP P ++WKKDG + + I +
Sbjct: 12795 PPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLC 12854
Query: 895 IIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTP 954
+ + R SG Y + + ++A+I ++++D+PGPP VKI ++ + L+W P
Sbjct: 12855 TLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEP 12914
Query: 955 PKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLS 1014
P +DG + IT Y + K + W V TS ++ +L+ G+EY FR+ +EN G+
Sbjct: 12915 PLEDGGSEITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVG 12974
Query: 1015 E 1015
+
Sbjct: 12975 D 12975
Score = 219 bits (557), Expect = 2e-56
Identities = 151/565 (26%), Positives = 257/565 (45%), Gaps = 42/565 (7%)
Query: 464 WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPD--AYNVTLPAKVHVIDP 521
W K+GLP++ES+ ++ L I NA E G Y D + +P V + P
Sbjct: 21100 WLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGP 21159
Query: 522 PK-----IILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTE 576
P I D + AD+ + L ++P +S + + + ++
Sbjct: 21160 PSKPKGPIRFDEIKADSVI-------LSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCS 21212
Query: 577 SYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVD-----FPDPPVAPTVTEV 631
S ++ V ++ +D + + +N G + + +V P PP P + V
Sbjct: 21213 SVARTTFKVPNLV-KDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNV 21271
Query: 632 GDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYE 691
D + W+ P YDGGS + G+ +E+K++ S W ++N + ++EG+ Y+
Sbjct: 21272 TSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQ 21331
Query: 692 VRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDG 751
R++A N+ G+S PS PS+ + ++ PP VT T+T++W PP G + + G
Sbjct: 21332 FRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVG 21391
Query: 752 YVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVK 811
Y +E +Q +E W+ N + + ++T+TGL + R+
Sbjct: 21392 YSIE--------KRQGNER-----------WVRCNFTDVSECQYTVTGLSPGDRYEFRII 21432
Query: 812 AVNAAGA-SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPE 870
A NA G S P S I+ ++ PP + I + GE++ + QG+P P
Sbjct: 21433 ARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPR 21492
Query: 871 LTWKKDGAEIDKN-QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQII 929
+TW KDG EI+K + I + T +F+R A R H G Y ++ K A I +++
Sbjct: 21493 VTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 21552
Query: 930 DRPGP-PQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRT 988
D PG ++ ++ GE + L W P +DG A IT Y I+K + + W + +
Sbjct: 21553 DTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQ 21612
Query: 989 SATITELVIGNEYYFRVFSENMCGL 1013
S T +L+ GNEY FRV + N G+
Sbjct: 21613 SYTAIKLINGNEYQFRVSAVNKFGV 21637
Score = 216 bits (551), Expect = 8e-56
Identities = 161/592 (27%), Positives = 267/592 (45%), Gaps = 52/592 (8%)
Query: 463 KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNV----TLPAKVHV 518
+W K + + RL++ L + +A+ D G+Y+ A NV ++ V V
Sbjct: 16079 QWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILK--AKNVAGERSVTVNVKV 16136
Query: 519 IDPP-----KIILDGLDADNTVTVIA-----GNKLRLEIPISGEPPPKAMWSRGDKAIME 568
+D P +++ G+ A+ G + + + +W+ D +
Sbjct: 16137 LDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQT 16196
Query: 569 GSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTV 628
S ++ + T I + G E E+ + PD P AP V
Sbjct: 16197 LSCKVTKLLEGNEYTFRIMAVNKYGVG--------EPLESEPVVAKNPFVVPDAPKAPEV 16248
Query: 629 TEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGV 688
T V D I+ WE PA DGGS ILGY +E++ K+ RW R + L E +IE
Sbjct: 16249 TTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENH 16308
Query: 689 AYEVRIFAVNAIGISKPSMPS---RPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIG 745
YE R+ A NA G+S+PS PS + P+ PP V +T ++V + W P + G
Sbjct: 16309 DYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPIYDG 16368
Query: 746 AAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDL-IDKTKFTITGLPTDA 804
+ GY++E C D+ +W + I+KT + L
Sbjct: 16369 GCEIQGYIVEKC------------------DVSVGEWTMCTPPTGINKTNIEVEKLLEKH 16410
Query: 805 KIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQ 864
+ R+ A+N AG E PI+V+E +E P I + L++ R G ++ L +P +
Sbjct: 16411 EYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIK 16470
Query: 865 GKPRPELTW-KKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETAS 923
G+P PE+ W K DG D I++ +S T + + R SGKY L ++ ++A
Sbjct: 16471 GRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLV--LDNVNRYDSGKYTLTLENSSGTKSAF 16528
Query: 924 IDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIE 983
+ ++++D P PP +K+ ++ ++V++TW PP DG + I Y ++K + + V+
Sbjct: 16529 VTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVT 16588
Query: 984 HYHRTSATITELVIGNEYYFRVFSENMCGL---SEDATMTKESAVIARDGKI 1032
+ H+ S I +L G YYFRV +EN G+ ++ A K + V GKI
Sbjct: 16589 NCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKI 16640
Score = 216 bits (550), Expect = 1e-55
Identities = 154/518 (29%), Positives = 249/518 (48%), Gaps = 36/518 (6%)
Query: 505 PDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDK 564
P N + AK +++ P+I LD + +V AG +++ IP G PPP W R D+
Sbjct: 20756 PIEMNEPVQAK-DILEAPEIDLD-VALRTSVIAKAGEDVQVLIPFKGRPPPTVTW-RKDE 20812
Query: 565 AIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHAS-IKVKVVDFPDPP 623
+ R E+ SS L I R+D+G Y + ++N GE +S + VKV+D P
Sbjct: 20813 KNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAAC 20872
Query: 624 VAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKK 683
V V + W+PP DGGSPI+ Y IE++ W ++ C T+F+
Sbjct: 20873 QKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHK-CSSTSFKLID 20931
Query: 684 MIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDH 743
+ E + R+ A N IGI +P + P V +P L++ T T+V + W PD
Sbjct: 20932 LSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDF 20991
Query: 744 IGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKT-KFTITGLPT 802
G + + YV+E +G + W A I KT + ++ L
Sbjct: 20992 DGGSVITEYVVERKGKGE------------------QTWSHAG---ISKTCEIEVSQLKE 21030
Query: 803 DAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIP 862
+ + RV A N G S+P PI VKE+I P++ + R+G V+L +P
Sbjct: 21031 QSVLEFRVFAKNEKGLSDPVTIG-PITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELP 21089
Query: 863 FQGKPRPELTWKKDGAEIDKNQ-INIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVET 921
++GKP+P ++W KDG + +++ + +E + I+ A++ H GKY V +D V
Sbjct: 21090 YKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYT--VILDNAVCR 21147
Query: 922 ASIDIQIIDRPGPPQI----VKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSME 977
++ I +I GPP ++ +++ ++V L+W P+D+G IT Y+I+K +
Sbjct: 21148 IAVPITVITL-GPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTN 21206
Query: 978 WFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1015
W V RT+ + LV EY FRV +EN G+S+
Sbjct: 21207 WKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQ 21244
Score = 214 bits (546), Expect = 3e-55
Identities = 142/494 (28%), Positives = 224/494 (45%), Gaps = 36/494 (7%)
Query: 573 IRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG-----EAHASIKVKVVDFPDPPVAPT 627
+ S P T I V+ I +N+ G ++ + P P PT
Sbjct: 9768 VHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPT 9827
Query: 628 VTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETT----FEPKK 683
V+ V + +NWE P YDGGSP+ GY++E K S RW R+N D K T ++
Sbjct: 9828 VSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKVTG 9887
Query: 684 MIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRP 740
+IEG Y+ R++A+NA G+ S+PS P P+A PP V T ++ + W P
Sbjct: 9888 LIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPP-FPKVTDWTKSSADLEWSP 9946
Query: 741 PDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGL 800
P G + + GY++EY EG E+W + TK +TGL
Sbjct: 9947 PLKDGGSKVTGYIVEYKEEGK------------------EEWEKGKDKEVRGTKLVVTGL 9988
Query: 801 PTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLV 860
A RV+AVN AG EP + I +K+ + P +++ ++ + G + ++
Sbjct: 9989 KEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRII 10048
Query: 861 IPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVE 920
GKP P +TW + + + + I + + + I+ +RSH G Y L K +
Sbjct: 10049 AYVSGKPPPTVTWNMNERTLPQ-EATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGER 10107
Query: 921 TASIDIQIIDRPGPPQIVKI-EDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF 979
+I + ++D PGP + ++ E+ LTW P+DDG + IT Y I+K + W
Sbjct: 10108 KKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWT 10167
Query: 980 TVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYE 1039
V R +AT+ L+ G Y+FR+ +EN G+ T E+ VI + + P E
Sbjct: 10168 PVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMG-PFVETSEALVIREPITVPERP--E 10224
Query: 1040 DFDFSEAPMFTQPL 1053
D + E T L
Sbjct: 10225 DLEVKEVTKNTVTL 10238
Score = 211 bits (537), Expect = 3e-54
Identities = 160/553 (28%), Positives = 257/553 (46%), Gaps = 70/553 (12%)
Query: 502 VFAPDAYNVTLPAKV--HVI--DP---PKIILDGLDADNTVTVIAGNKLRLEIPISGEPP 554
V A +A V+ P+++ +V+ DP P I L+ D + VI G KL + +P P
Sbjct: 7863 VRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHD----IIVIEGEKLSIPVPFRAVPV 7918
Query: 555 PKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKV 614
P W + K + + S R+ ++ S+ L + + R D+G+Y I L+N+ G A ASI V
Sbjct: 7919 PTVSWHKDGKEV-KASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINV 7977
Query: 615 KVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLC 674
KV+ P P +++ C + WEPP +DGG+PIL Y +ER++ ++ +
Sbjct: 7978 KVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGEN 8037
Query: 675 KETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTD 731
K ++ K +I Y R+ AVN +G + P + P PP + V + T
Sbjct: 8038 K-LSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTA 8096
Query: 732 TTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLID 791
+T+ W+PP + G + + GY++E +G E W N+ L+
Sbjct: 8097 EAMTITWKPPLYDGGSKIMGYIIEKIAKGE------------------ERWKRCNEHLVP 8138
Query: 792 KTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIR 851
+T GL + RV+A NAAG SEP + P + I+ PK+ + L+ ++
Sbjct: 8139 ILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLE---VK 8195
Query: 852 RVGEAVNLVIPFQGKPRPELTWKKD-----GAEIDK------------------------ 882
R G+ + L G P P +TW KD EI K
Sbjct: 8196 R-GDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLT 8254
Query: 883 NQINIRNSET-DTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIE 941
+++I NS+ ++ + +R + R G Y ++V+ D + A + ++D PGPP E
Sbjct: 8255 QRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFE 8314
Query: 942 DVWGENVALTWTPPKDDGNAAITGYTIQKAD--KKSMEWFTVIEHYHRTSATITELVIGN 999
D+ +V W PP DDG + I YT++K D K EW V ++T+L+ G
Sbjct: 8315 DIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGK 8374
Query: 1000 EYYFRVFSENMCG 1012
EY FRV +EN G
Sbjct: 8375 EYLFRVRAENRFG 8387
Score = 210 bits (535), Expect = 5e-54
Identities = 177/671 (26%), Positives = 293/671 (43%), Gaps = 79/671 (11%)
Query: 380 EIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPL 439
+++ G K +RIR + GA A + + + A P +L P
Sbjct: 13840 DLVEGGKYEFRIRAKNTA------GAISAPSESTETIICKDEYEA-------PTIVLDPT 13886
Query: 440 TDQ--TVNLGKEICLKCE--ISENIP-GKWTKNGLPVQESDRLKVVHKGRIHKLVIANAL 494
T+ G I L + + +P W+K G ++ SD ++ L I A
Sbjct: 13887 IKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYAT 13946
Query: 495 TEDEGDY-VFAPDAYNVTLP-AKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGE 552
+D G+Y + A + + + KV V+D P G ++ ++ K L +
Sbjct: 13947 RKDAGEYTITATNPFGTKVEHVKVTVLDVP-----GPPGPVEISNVSAEKATL----TWT 13997
Query: 553 PPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLK----NE---- 604
PP + S I+E ++S L+ + D H+ K NE
Sbjct: 13998 PPLEDGGSPIKSYILEKR---------ETSRLLWTVVSEDIQSCRHVATKLIQGNEYIFR 14048
Query: 605 --------AGEAHASIKVKVVDF---PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILG 653
GE S VK+VD P PP P V+ V + ++W+ P DGGS I G
Sbjct: 14049 VSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITG 14108
Query: 654 YFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV 713
Y +ER++K+S RW+R + + + EG YE R+ A N GI PS S +
Sbjct: 14109 YHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVL 14168
Query: 714 PLAVTSPPTLLTVDSVTDTT---VTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDEN 770
PP + VTDTT ++ W P + G + GYV+E+ G A D
Sbjct: 14169 MKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGD-EAWIKDTT 14227
Query: 771 GEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILV 830
G A + T+F + L T K R+ A+N AG EP +V
Sbjct: 14228 GTA----------------LRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIV 14271
Query: 831 KEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNS 890
+ + P + L++T + R G ++ + +P +G+P PE+TW KD + KN+ NI N+
Sbjct: 14272 EREMAPD-FELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINL-KNRANIENT 14329
Query: 891 ETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVAL 950
E+ T++ I + R +GK+ + ++ ++ ++++++D PGP ++ D+ ++V L
Sbjct: 14330 ESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTL 14389
Query: 951 TWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENM 1010
W P DG + IT Y ++K + + T H+ + +T L G EY+FRV +EN
Sbjct: 14390 HWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENE 14449
Query: 1011 CGLSEDATMTK 1021
G+ E T+
Sbjct: 14450 YGIGEPTETTE 14460
Score = 207 bits (527), Expect = 5e-53
Identities = 119/408 (29%), Positives = 212/408 (51%), Gaps = 24/408 (5%)
Query: 620 PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTF 679
P PP P VT++ + + W P DGGS I GYF+E++ K+S W ++ + ++T
Sbjct: 20569 PGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQ 20628
Query: 680 EPKKMIEGVAYEVRIFAVNAIG---ISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTM 736
+ + E Y+ R+ AVNA G S+PS + P+ PP + + T +++T+
Sbjct: 20629 KVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITL 20688
Query: 737 RWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWI-VANKDLIDKTKF 795
W P + G + + GYV+E +Q +E E+W V+ K + T++
Sbjct: 20689 GWSKPVYDGGSAVTGYVVEI--------RQGEE----------EEWTTVSTKGEVRTTEY 20730
Query: 796 TITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGE 855
++ L + RV AVN AG EP ++P+ K+I+E P+I + L+ + I + GE
Sbjct: 20731 VVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGE 20790
Query: 856 AVNLVIPFQGKPRPELTWKKDGAEIDKN-QINIRNSETDTIIFIRKAERSHSGKYDLQVK 914
V ++IPF+G+P P +TW+KD + + + +I N+++ +++ I + R+ +GKY L ++
Sbjct: 20791 DVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIE 20850
Query: 915 VD-KFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADK 973
+++++ ++++D P Q ++++ V V L W PP DG + I Y I+K D
Sbjct: 20851 NGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDA 20910
Query: 974 KSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTK 1021
W V TS + +L ++FRV +EN G+ E T+
Sbjct: 20911 TKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTE 20958
Score = 206 bits (525), Expect = 8e-53
Identities = 160/599 (26%), Positives = 279/599 (46%), Gaps = 50/599 (8%)
Query: 444 VNLGKEICLKCEI-SENIPGK-WTKNGLPVQESD-RLKVVHKGRIHKLVIANALTEDEGD 500
V+ G+ L+ +I + IP W+K+G ++E+ R+++ + LV+ + + D G
Sbjct: 18222 VHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 18281
Query: 501 YVFAPDAYNVT--LPAKVHVIDPP-----KIILDGLDAD------NTVTVIAGNKLRLEI 547
Y+ T +P V V+D P + + G+ A+ N G + I
Sbjct: 18282 YILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYI 18341
Query: 548 PISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGE 607
I + W++ + + ++ T+ P + + +A Y I E+G
Sbjct: 18342 -IEKRETSRLSWTQVSTEVQALNYKV-TKLLPGNEYIFRVMAVNK----YGIGEPLESGP 18395
Query: 608 AHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWM 667
A K P PP P V+ + D ++ W P DGG+ I GY +E++ K+ RW
Sbjct: 18396 VTACNPYKP---PGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWT 18452
Query: 668 RLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVD 727
+ N + + EG +YE R+ A NA G+ +PS PS + PP +
Sbjct: 18453 KCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNP 18512
Query: 728 SVTDT---TVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIV 784
VTDT +V++ W P + G A + GYV+E EAA A++W
Sbjct: 18513 KVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEV--------------KEAA----ADEWTT 18554
Query: 785 ANKDL-IDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPR 843
+ +FT+T L + + R+ A+N+ G EP ++ +E IEPP+I +
Sbjct: 18555 CTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDA 18614
Query: 844 HLKQTYIRRVGEAVNLVIPFQGKPRPELTWKK-DGAEIDKNQINIRNSETDTIIFIRKAE 902
L++ + R + L + +G+P PE+ W+K +G D+ QI + +S T++ I
Sbjct: 18615 DLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSS--FTMLVIDNVT 18672
Query: 903 RSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAA 962
R SG+Y+L ++ + +TA ++++++D P P + I +V ++V L+W PP DG A
Sbjct: 18673 RFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAK 18732
Query: 963 ITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTK 1021
IT Y ++K + + T+ + +T+ I L G YYFRV + N G+ A T+
Sbjct: 18733 ITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTE 18791
Score = 206 bits (524), Expect = 1e-52
Identities = 159/616 (25%), Positives = 268/616 (43%), Gaps = 73/616 (11%)
Query: 434 KILTPLTDQTVNLGKEICLKCEISENIPG----------KWTKNGLPVQESDRLKVVHKG 483
K++ P + V L + + +K + P KWT +G ++ + V
Sbjct: 11007 KLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDN 11066
Query: 484 RIHKLVIANALTEDEGDYVFAPD--AYNVTLPAKVHVID---PPKIILDGLDADNTVTVI 538
L I N L D G+Y A + T+ + V+D PP ++ LD
Sbjct: 11067 FSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPE---- 11122
Query: 539 AGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIR-----TESYPDSSTLVIDIAERDD 593
+ IS +PP S I+E + S + L I ++
Sbjct: 11123 -------HMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGC 11175
Query: 594 SGVYHINLKNEAG-----EAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGG 648
V+ + +N+ G ++ ++ P PP P VT++ ++ ++W P DGG
Sbjct: 11176 EYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGG 11235
Query: 649 SPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMP 708
SPI GY++ER++ + +W+R+N + F + EG YE R+FA N G+SKPS
Sbjct: 11236 SPITGYYMERREV-TGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPS 11294
Query: 709 SRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAK 765
S P P+ PP + + T + W P G + + GYV+E C + T+
Sbjct: 11295 SDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVE-CQKPGTA-- 11351
Query: 766 QSDENGEAAYDLPAEDWIVANKD-LIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYY 824
W NKD LI + F + GL + R+KA N G EP+
Sbjct: 11352 ---------------QWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPREL 11396
Query: 825 SQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ 884
++ ++ K+I+ PP++ + + RVG+ + ++ +G+P P++TW K+G +
Sbjct: 11397 AESVIAKDILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEG------K 11450
Query: 885 INIRNSETDTI-------IFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQI 937
+ +R D I + I++A R+ GKY + K S + ++DRPGP Q
Sbjct: 11451 VLVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQN 11510
Query: 938 VKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVI 997
+K+ +V EN ++W P D+G + IT + ++ W V + L+
Sbjct: 11511 LKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIVASDVTKRLIK-ANLLA 11569
Query: 998 GNEYYFRVFSENMCGL 1013
NEYYFRV +EN G+
Sbjct: 11570 NNEYYFRVCAENKVGV 11585
Score = 204 bits (520), Expect = 3e-52
Identities = 127/423 (30%), Positives = 206/423 (48%), Gaps = 36/423 (8%)
Query: 611 SIKVKVVD---FPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWM 667
S KV + D P PP P V +++W PP +GGSPI GY++E++++ S W
Sbjct: 9090 SDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWS 9149
Query: 668 RLNFDLC-----KETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTS 719
R++ K F +++EGV Y+ R A+NA GI PS PS P V P+
Sbjct: 9150 RVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPG 9209
Query: 720 PPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPA 779
PP+ V T +++++ W+PP G + + GY++E EG+T K+ +E +
Sbjct: 9210 PPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDK------- 9262
Query: 780 EDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKI 839
LI + + L K RVKAVN AG SEP + I +I E P++
Sbjct: 9263 ---------LITTCECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEV 9313
Query: 840 RIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWK---------KDGAEIDKNQINIRNS 890
I + + + G + + +G+P P+ +W+ KDG + +
Sbjct: 9314 FIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETA 9373
Query: 891 ETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVAL 950
E ++I I + +RSH+GKY + K +TA+ ++++D PGPP+ +K+ D+ + L
Sbjct: 9374 ENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRL 9433
Query: 951 TWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENM 1010
+W P DDG I GY I+K W V T+ + +L+ +Y+FRV +EN
Sbjct: 9434 SWKMPDDDGGDRIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENR 9493
Query: 1011 CGL 1013
G+
Sbjct: 9494 FGI 9496
Score = 204 bits (518), Expect = 5e-52
Identities = 146/522 (27%), Positives = 236/522 (45%), Gaps = 39/522 (7%)
Query: 520 DPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYP 579
+PP + LD + + ++AG LR+ ++G P P +W++ + + R+ ++
Sbjct: 8603 EPPAVELD-VSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGEL--DKDRVVIDNVG 8659
Query: 580 DSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMN 639
S L+I A R D G Y I N G A+ +V+V D P P + C++N
Sbjct: 8660 TKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLN 8719
Query: 640 WEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNA 699
W P DGGS I G+ IERK + W R + + + + ++EG Y+ R+ A N
Sbjct: 8720 WSDPEDDGGSEITGFIIERKDAKMHTW-RQPIE-TERSKCDITGLLEGQEYKFRVIAKNK 8777
Query: 700 IGISKPSM--PSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 757
G P P PL + P LT T +T+T+ W+ P G + + GY++E
Sbjct: 8778 FGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIE-- 8835
Query: 758 FEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAG 817
+ +D P D+ NK L T F + L RVKAVN G
Sbjct: 8836 --------------KRRHDKP--DFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIG 8879
Query: 818 ASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIR-RVGEAVNLVIPFQGKPRPELTWKKD 876
SEP +++++ PP I++ ++ I+ + GE V++ G P P++ W K+
Sbjct: 8880 ESEPS-LPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKN 8938
Query: 877 GAEIDK-------NQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQII 929
I+K + + SE T + I KA R G Y + ++ +++
Sbjct: 8939 ETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVY 8998
Query: 930 DRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKAD--KKSMEWFTVIEHYHR 987
DRP PP+ + + D+ E+ LTW P D+G + IT Y I K D +K EW V
Sbjct: 8999 DRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVE 9058
Query: 988 TSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARD 1029
I +L+ +Y FRV + N G+S++ K V+ +D
Sbjct: 9059 KRYGIWKLIPNGQYEFRVRAVNKYGISDEC---KSDKVVIQD 9097
Score = 203 bits (516), Expect = 9e-52
Identities = 164/613 (26%), Positives = 270/613 (44%), Gaps = 62/613 (10%)
Query: 443 TVNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGD 500
T+ G ++ L + K WTK + +++ + + G+ VI D G
Sbjct: 22561 TIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGK 22620
Query: 501 YVFAPDAYNVT--LPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPP---- 554
Y + T + V V+D P G TV+ + K L + E
Sbjct: 22621 YTLTVKNASGTKAVSVMVKVLDSP-----GPCGKLTVSRVTQEKCTLAWSLPQEDGGAEI 22675
Query: 555 -----PKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG--- 606
+ SR + I+EG T SY V+ +++ ++ + N+ G
Sbjct: 22676 THYIVERRETSRLNWVIVEGE--CPTLSY------VVTRLIKNNEYIFRVRAVNKYGPGV 22727
Query: 607 --EAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSS 664
E+ + P PP P G + I+ W P DGG+ I Y +++++K+S
Sbjct: 22728 PVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSL 22787
Query: 665 RWMRLNFD-LCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV----PLAVTS 719
RW R+N D + +T + ++EG Y+ R+ AVNA G S+PS S F+ P
Sbjct: 22788 RWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASN-FISCREPSYTPG 22846
Query: 720 PPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPA 779
PP+ V T ++++ W P + G + GYVLE K +D+
Sbjct: 22847 PPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEM------QEKDTDQ---------- 22890
Query: 780 EDWI-VANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPK 838
W V I T+FT+ L K RV AVN G SE I E IE P
Sbjct: 22891 --WYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPD 22948
Query: 839 IRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFI 898
+ + LK+T R G ++ L++ G+P P +TW K G ++ I I +E+ +++ +
Sbjct: 22949 LELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAI-IDTTESYSLLIV 23007
Query: 899 RKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDD 958
K R +GKY ++ + ++A++ +++ D PGP VK+++V ++V +TW P D
Sbjct: 23008 DKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTID 23067
Query: 959 GNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE--- 1015
G A + Y ++K + + TV +T I+ LV G YYFRV EN+ G+ E
Sbjct: 23068 GGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCE 23127
Query: 1016 --DATMTKESAVI 1026
DA + E ++
Sbjct: 23128 TSDAVLVSEVPLV 23140
Score = 201 bits (512), Expect = 3e-51
Identities = 157/613 (25%), Positives = 280/613 (45%), Gaps = 46/613 (7%)
Query: 420 GQSSAKLSVDLKPLKILTPLTDQ-TVNLGKEICLKCEI-SENIPG-KWTKNGLPVQESDR 476
G +AK V+L + + D VN G+ L+ ++ + +P +W + ++ES R
Sbjct: 17115 GPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESAR 17174
Query: 477 LKVVHKGRIHKLVIANALTEDEGDYVFAPD--AYNVTLPAKVHVIDPPKIILDGLDADNT 534
++ + L++ +A+ D G Y+ A + + P V V+D P +
Sbjct: 17175 CEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRP----GPPEGPVQ 17230
Query: 535 VTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIR-----TESYPDSSTLVIDIA 589
VT + K L + PP + S ++E R S +++L +
Sbjct: 17231 VTGVTSEKCSL----TWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKL 17286
Query: 590 ERDDSGVYHINLKNE--AGEAHASIKVKVVD---FPDPPVAPTVTEVGDDWCIMNWEPPA 644
+ V+ I N+ GE S V + + P PP + VT + D + W P
Sbjct: 17287 LEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPD 17346
Query: 645 YDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISK 704
DGGS I+GY +E++ + RW++ N + + E YE R+ A NA G+ +
Sbjct: 17347 SDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGE 17406
Query: 705 PSMPS---RPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGS 761
PS + + P+ PPT + T ++T+ W P + G + + GYV+E C
Sbjct: 17407 PSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEIC---- 17462
Query: 762 TSAKQSDENGEAAYDLPAEDW-IVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASE 820
++DE E+W IV + + T+F I+ L + +RV A+N G E
Sbjct: 17463 ----KADE----------EEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGE 17508
Query: 821 PKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI 880
+ ++ +E P++ + L++ + R G + + IPF+G+P PE+TW ++ E
Sbjct: 17509 ATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEF 17568
Query: 881 DKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKI 940
+++ I T + I +R+ +GKY L+++ ++A + ++++D PGPPQ + +
Sbjct: 17569 T-DKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAV 17627
Query: 941 EDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNE 1000
++V ++ L W PP DG A + Y I K + + V +TS + L G
Sbjct: 17628 KEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAI 17687
Query: 1001 YYFRVFSENMCGL 1013
YYFRV +EN G+
Sbjct: 17688 YYFRVMAENEFGV 17700
Score = 201 bits (510), Expect = 4e-51
Identities = 139/497 (27%), Positives = 230/497 (46%), Gaps = 32/497 (6%)
Query: 620 PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTF 679
P P P V V + + WE P +DGGS I+GY++E+K++ + W++ N C E +
Sbjct: 22344 PSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNY 22403
Query: 680 EPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWR 739
+ ++EG+ Y+ R +A+NA G+SK S SRP + P V VT +TV++ W
Sbjct: 22404 KVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAPGRPEVTDVTRSTVSLIWS 22463
Query: 740 PPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITG 799
P + G + + GY++E K E G+ W+ N ++ FT+T
Sbjct: 22464 APAYDGGSKVVGYIIE--------RKPVSEVGDGR-------WLKCNYTIVSDNFFTVTA 22508
Query: 800 LPTDAKIFVRVKAVNAAGA-SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIR-RVGEAV 857
L RV A NAAG S+ + P+ ++ PPK + L + R G +
Sbjct: 22509 LSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDL 22568
Query: 858 NLVIPFQGKPRPELTWKKDGAEIDK-NQINIRNSETDTIIFIRKAERSHSGKYDLQVKVD 916
L GKP P++ W K E+D +++++ + I+ +RS SGKY L VK
Sbjct: 22569 VLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNA 22628
Query: 917 KFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSM 976
+ S+ ++++D PGP + + V E L W+ P++DG A IT Y +++ + +
Sbjct: 22629 SGTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRL 22688
Query: 977 EWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNP 1036
W V S +T L+ NEY FRV + N G + ++AR+ +P
Sbjct: 22689 NWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYG---PGVPVESEPIVARNSFTIPSP 22745
Query: 1037 --VYEDFDFSEAPM---FTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMK-NKVAIVDD 1090
+ E+ + + +T+P + G N N V K + W + NK +V D
Sbjct: 22746 PGIPEEVGTGKEHIIIQWTKPESD-----GGNEISNYLVDKREKKSLRWTRVNKDYVVYD 22800
Query: 1091 PRYRMFSNQGVCTLEIR 1107
R ++ S C + R
Sbjct: 22801 TRLKVTSLMEGCDYQFR 22817
Score = 196 bits (497), Expect = 1e-49
Identities = 219/924 (23%), Positives = 366/924 (39%), Gaps = 131/924 (14%)
Query: 263 QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 322
+V + V F E+ + KW++N + I S+KYI K L I + + D + Y
Sbjct: 6153 RVKEQQEVVFNCEVNTEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANY 6212
Query: 323 YVTAGDE-----KCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKN 377
V+ + K + L V E + + + L+D + V C+V+ + +KW KN
Sbjct: 6213 NVSLTNHRGENVKSAANLIVEEEDLRIVEPLKDIETMEKKSVTFWCKVNRLNVTLKWTKN 6272
Query: 378 GEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILT 437
GEE+ + YR V+ KH+L I+ D EY V +S A+L + P + +
Sbjct: 6273 GEEVPFDNRVSYR--VDKYKHMLTIKDCGFPDEGEYIVTAGQDKSVAELLIIEAPTEFVE 6330
Query: 438 PLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTE 496
L DQTV + C++S E KW +NG ++E + K G IH+L+I + +
Sbjct: 6331 HLEDQTVTEFDDAVFSCQLSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLD 6390
Query: 497 DEGDYVFAPD-----AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISG 551
DE +Y + A V +I PP+ IL+ AD V + NK ++E+
Sbjct: 6391 DECEYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGAD-VVFLAELNKDKVEV---- 6445
Query: 552 EPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHAS 611
W R + +++G + DI RD G Y K++ EA A
Sbjct: 6446 ------QWLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQ-GEYRFIAKDK--EARAK 6496
Query: 612 IKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYF-IERKKKQSSRWMRLN 670
+++ AP + D + D G P+ + K + W + N
Sbjct: 6497 LELAA--------APKIKTADQDLVV--------DVGKPLTMVVPYDAYPKAEAEWFKEN 6540
Query: 671 FDL--------CKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPT 722
L ++T+F + +G +I N G ++ + + + V P
Sbjct: 6541 EPLSTKTIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKV---IDVPGPVR 6597
Query: 723 LLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDW 782
L V D V++ W P G + + GYV+E D+ + W
Sbjct: 6598 NLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVE------------------RRDIKRKTW 6639
Query: 783 IVANKDLIDKTKFTITGLPTDAKIFV-RVKAVNAAGASEPKYYSQPILVKEIIEPPKIRI 841
++A D + +FT+TGL ++ RV A N G EP P+ + + P
Sbjct: 6640 VLAT-DRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVP---- 6694
Query: 842 PRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKD----GAEIDKNQINIRNSET---DT 894
G +N+ I + LTW+ GAEI I +R+ + DT
Sbjct: 6695 ------------GPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDT 6742
Query: 895 IIFIRKAERS-------HSGKYDLQVKVDKFV-----ETASIDIQI---IDRPGPPQIVK 939
+ +R + S +Y +V+ + A+ +++ I+RP PP +
Sbjct: 6743 AMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLT 6802
Query: 940 IEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV-IEHYHRTSATITELVIG 998
D +V L W PP DG + I GY I++ ++ W ++ + +T L G
Sbjct: 6803 SSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKG 6862
Query: 999 NEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYA 1058
N+Y +RV +EN G+S+ + + P+ D F E M +
Sbjct: 6863 NKYLYRVSAENKAGVSDPSEIL--------------GPLTADDAFVEPTMDLSAFKDGLE 6908
Query: 1059 IAGYNA-TLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTY 1117
+ N T+ G P+P TW + R +M + L I D G Y
Sbjct: 6909 VIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIY 6968
Query: 1118 CCKAVNDLGTVEIECKLEVKVIAQ 1141
K N + T+ E ++V VIA+
Sbjct: 6969 TLKLENRVKTISGE--IDVNVIAR 6990
Score = 195 bits (496), Expect = 2e-49
Identities = 141/519 (27%), Positives = 228/519 (43%), Gaps = 38/519 (7%)
Query: 518 VIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTES 577
++ PP++ LD + + +TV G +R+ + G P P W++ K ++ R +
Sbjct: 11405 ILHPPEVELD-VTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREK---RVDL 11460
Query: 578 YPDSSTLVIDIAE--RDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDW 635
D + + I E R D G Y I+ KN +G A S V V+D P P VT V +
Sbjct: 11461 IQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKEN 11520
Query: 636 CIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIF 695
C ++WE P +GGS I + +E +K W + D+ K ++ Y R+
Sbjct: 11521 CTISWENPLDNGGSEITNFIVEYRKPNQKGWSIVASDVTKRLI--KANLLANNEYYFRVC 11578
Query: 696 AVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGY 752
A N +G+ P + P+ P L + T V ++WR PD+ G + Y
Sbjct: 11579 AENKVGVGPTIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSY 11638
Query: 753 VLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKA 812
+E +GS +DW +K I +T + + + RV+
Sbjct: 11639 HVERRLKGS------------------DDWERVHKGSIKETHYMVDRCVENQIYEFRVQT 11680
Query: 813 VNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELT 872
N G S+ ++ ++VKE ++ P + + L + G+ + L +GKP PE+
Sbjct: 11681 KNEGGESD-WVKTEEVVVKEDLQKPVLDLK--LSGVLTVKAGDTIRLEAGVRGKPFPEVA 11737
Query: 873 WKKDGAEIDKNQ---INIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQII 929
W KD D + + I + + KA+RS GKY + A + ++
Sbjct: 11738 WTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVL 11797
Query: 930 DRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTS 989
D+PGP + +KI DV + + W PP+DDG I Y ++K + K M W T
Sbjct: 11798 DKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPG 11857
Query: 990 ATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIAR 1028
T+T L+ GNEY FRV +EN G T+ VIA+
Sbjct: 11858 TTVTRLIEGNEYIFRVRAENKIGTGPP---TESKPVIAK 11893
Score = 195 bits (495), Expect = 2e-49
Identities = 123/422 (29%), Positives = 206/422 (48%), Gaps = 28/422 (6%)
Query: 620 PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTF 679
P PP A V +V + WEPP DGG PI Y IE+K++ +RW++ + F
Sbjct: 7687 PGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNF 7746
Query: 680 EPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTM 736
+IEG + ++ A N G+ PS P+ P + SPP L V + +
Sbjct: 7747 RVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAI 7806
Query: 737 RWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFT 796
W+PP+ G + + GY +E C G+ E W+ N I KF
Sbjct: 7807 AWKPPEKNGGSPIIGYHVEMCPVGT------------------EKWMRVNSRPIKDLKFK 7848
Query: 797 IT-GLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGE 855
+ G+ D + +RV+AVNA G SEP S+ ++ K+ P I + H I GE
Sbjct: 7849 VEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETH---DIIVIEGE 7905
Query: 856 AVNLVIPFQGKPRPELTWKKDGAEID-KNQINIRNSETDTIIFIRKAERSHSGKYDLQVK 914
+++ +PF+ P P ++W KDG E+ +++ ++N + + K+ R+ +G Y + ++
Sbjct: 7906 KLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLE 7965
Query: 915 VDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKK 974
TASI++++I PGP + +K D+ + LTW PP+ DG I Y +++ +
Sbjct: 7966 NKLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAG 8025
Query: 975 SMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYK 1034
+ V+ ++ S T+ +L+ EY+FRV + N G E + ++ VIA+D K
Sbjct: 8026 RRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIEL--KNPVIAQDPKQPP 8083
Query: 1035 NP 1036
+P
Sbjct: 8084 DP 8085
Score = 194 bits (493), Expect = 4e-49
Identities = 148/575 (25%), Positives = 258/575 (44%), Gaps = 49/575 (8%)
Query: 464 WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAK----VHVI 519
W K+G+ +++ +++ L + +A + G V+ +A N + AK V V
Sbjct: 21495 WFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRG--VYTVEAKNASGSAKAEIKVKVQ 21552
Query: 520 DPPKIILDGLDADNTVTVIAGNKLRL--EIPISGEPPP-------KAMWSRGDKAIMEGS 570
D P ++ + N I G K+ L + P++ P K SR A++E
Sbjct: 21553 DTPGKVVGPIRFTN----ITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIED- 21607
Query: 571 GRIRTESYPDSSTLVIDIAERDDSGV--YHINLKNEAGEAHASIKVKVVDFPDPPVAPTV 628
+ +SY + + + S V + + ++ A I+ V PD P P
Sbjct: 21608 -KCEAQSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTV---PDAPGIPEP 21663
Query: 629 TEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMR-LNFDLCKETTFEPKKMIEG 687
+ + + + W P DGGS I Y +ER++K+S+RW++ ++ ET F+ + EG
Sbjct: 21664 SNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEG 21723
Query: 688 VAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHI 744
YE + A NA G+ S SR P+ PPT++ V + TTV++ W P
Sbjct: 21724 NEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFD 21783
Query: 745 GAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDA 804
G + GY++E C DW N + KT++T+T L
Sbjct: 21784 GGMEIIGYIIEMC------------------KADLGDWHKVNAEACVKTRYTVTDLQAGE 21825
Query: 805 KIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQ 864
+ RV A+N AG + + I + + P++ I + KQT++ R G ++ L I +Q
Sbjct: 21826 EYKFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQ 21885
Query: 865 GKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASI 924
G+P P W K + + + +I +++ + + + R+ +GKY L V+ + ++ +
Sbjct: 21886 GRPTPTAVWSKPDSNLSL-RADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITF 21944
Query: 925 DIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEH 984
++++D PGPP + +DV + L W P DG A I Y ++K + W + E
Sbjct: 21945 TVKVLDTPGPPGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEK 22004
Query: 985 YHRTSATITELVIGNEYYFRVFSENMCGLSEDATM 1019
R + +L G YYFRV + N G+ E M
Sbjct: 22005 CTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEM 22039
Score = 185 bits (470), Expect = 2e-46
Identities = 172/692 (24%), Positives = 288/692 (41%), Gaps = 92/692 (13%)
Query: 373 KWFKNGEEIIP-----------GPKSRYRIRVEGKKHILIIEGATKA-------DAAEYS 414
+W + E ++P G + ++R+R E I AT DA +
Sbjct: 8128 RWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVI 8187
Query: 415 VMTT-----GGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKC---------EISENI 460
+ T+ G + + S+ P +T + D+ V + +EI + E+ E
Sbjct: 8188 LRTSLEVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEE 8247
Query: 461 PGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYN--VTLPAKVHV 518
P LP+ + + KG +L + ++L D G Y+ + + P V V
Sbjct: 8248 PFV-----LPLTQRLSIDNSKKGE-SQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSV 8301
Query: 519 IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESY 578
+D P ++ + D T + EPP G I+ + + ++
Sbjct: 8302 LDTPGPPINFVFEDIRKTSVL---------CKWEPP----LDDGGSEIINYTLEKKDKTK 8348
Query: 579 PDSSTLVIDIAERD-----------DSGVYHINLKNEAGEAHASIKVKVVDF-----PDP 622
PDS +V+ R ++ + +N G + +V PD
Sbjct: 8349 PDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPFGPPDA 8408
Query: 623 PVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPK 682
P P V +V + ++ W P D GSPILGY++E+++ S+ W R+N L
Sbjct: 8409 PDKPIVEDVTSNSMLVKWNEPK-DNGSPILGYWLEKREVNSTHWSRVNKSLLNALKANVD 8467
Query: 683 KMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSP--PTLLTVDSVTDTTVTMRWRP 740
++EG+ Y R+ A NA G K S PS P SP P + V + TT+ + W P
Sbjct: 8468 GLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIELEWEP 8527
Query: 741 PDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGL 800
P G + GY ++ G+ +W + +I ++T+ +
Sbjct: 8528 PAFNGGGEIVGYFVDKQLVGT------------------NEWSRCTEKMIKVRQYTVKEI 8569
Query: 801 PTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLV 860
A +RV AVNAAG P +QP+ V E EPP + + +K G+ + +
Sbjct: 8570 REGADYKLRVSAVNAAGEGPPG-ETQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIP 8628
Query: 861 IPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVE 920
G+P P W K+ E+DK+++ I N T + + I+ A R G+Y + +
Sbjct: 8629 AVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSK 8688
Query: 921 TASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFT 980
A+ +++ D PGP +K + L W+ P+DDG + ITG+ I++ D K W
Sbjct: 8689 FAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQ 8748
Query: 981 VIEHYHRTSATITELVIGNEYYFRVFSENMCG 1012
IE R+ IT L+ G EY FRV ++N G
Sbjct: 8749 PIE-TERSKCDITGLLEGQEYKFRVIAKNKFG 8779
Score = 184 bits (467), Expect = 4e-46
Identities = 177/720 (24%), Positives = 313/720 (43%), Gaps = 79/720 (10%)
Query: 344 VTKQLEDTTAYCGERVELECE-VSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILII 402
+ K+++D T GE +L C+ V ++KW++ G+E+I K Y++ +G+ H L +
Sbjct: 24038 IRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRK--YKMSSDGRTHTLTV 24095
Query: 403 EGATKADAAEYSVMTTGG----QSSAKLSVDLKP-LKILTPLTDQTVN-LGKEICLKCE- 455
+ D Y+ + T ++S+KL + P PL ++ +G + L
Sbjct: 24096 MTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMY 24155
Query: 456 ISENIPGK-WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPA 514
I +P W +Q S+ + + + LV+ N + Y V L
Sbjct: 24156 IGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAG------KYKVQLSN 24209
Query: 515 KVHVIDPPKIILDGLDADN----TVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIME-- 568
+D ILD D T ++ L+ IS +PP S ++E
Sbjct: 24210 VFGTVDA---ILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKC 24266
Query: 569 -----GSGRIRTESYPDSSTLVIDIAERDDSGVY-HINLKNEAG-----EAHASIKVKV- 616
++ + + ++ ++++ E ++G Y ++ +N G E + + +K
Sbjct: 24267 EAKEGAEWQLVSSAISVTTCRIVNLTE--NAGYYFRVSAQNTFGISDPLEVSSVVIIKSP 24324
Query: 617 VDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKE 676
+ P P PT+T V D C++ W+PPA DGG+ I Y++E+++K+ ++W+ + + +E
Sbjct: 24325 FEKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRE 24384
Query: 677 TTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTM 736
T F K +IEG+ YE R+ N G S+ S S P P + + + + V
Sbjct: 24385 TVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRY 24444
Query: 737 RWRPPDHIGAAGLDGYVLEYCFEG----STSAKQSDENGEAAYDLPAEDWIVANKDLIDK 792
+ G ++++ +G + K + + Y
Sbjct: 24445 QSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYH---------------- 24488
Query: 793 TKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRR 852
+ I + D +V+A N G+ E+ P KI +P+ L+
Sbjct: 24489 -QLIIASVTDDDATVYQVRATNQGGSVSGT------ASLEVEVPAKIHLPKTLEGMGAVH 24541
Query: 853 V--GEAVNLVIPFQGKPRPELTWKKDGAEIDKN---QINIRNSETDTIIFIRKAERSHSG 907
GE V++ IPF GKP P +TW+K ID N Q+ + S T +++F ER +G
Sbjct: 24542 ALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFT-SLVFPNGVERKDAG 24600
Query: 908 KYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYT 967
Y + K ++ ++++ + D P PP+ VK+ DV ++V LTWT P DG + IT Y
Sbjct: 24601 FYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYI 24660
Query: 968 IQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE-----DATMTKE 1022
++K + W V T T+ L Y FRV +EN GLS+ + T+TKE
Sbjct: 24661 VEKCATTAERWLRV-GQARETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKE 24719
Score = 169 bits (427), Expect = 2e-41
Identities = 165/704 (23%), Positives = 284/704 (40%), Gaps = 93/704 (13%)
Query: 350 DTTAYCGERV-ELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKA 408
D CGE V E + EV+ + KW+ YR++ + +GA+K
Sbjct: 7135 DKWVACGEPVAETKMEVTGLEEG-KWYA------------YRVKALNR------QGASKP 7175
Query: 409 DAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGK--WTK 466
+ Q + ++ +D+K L LT V G +I L ++ K WTK
Sbjct: 7176 SRPTEEIQAVDTQEAPEIFLDVKLLAGLT------VKAGTKIELPATVTGKPEPKITWTK 7229
Query: 467 NGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNV----TLPAKVHVIDP- 521
+ +++ R+ + + + + I ++ D G Y+ +A NV T +V+V+D
Sbjct: 7230 ADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYII--EAVNVCGRATAVVEVNVLDKP 7287
Query: 522 -PKIILDGLDADNTVTVIAGNKLR-------LEIPISGEPPPKAMWSRGDKAIMEGSGRI 573
P D D N ++ N R + +W + + + + +
Sbjct: 7288 GPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFK- 7346
Query: 574 RTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGD 633
T+ P+ + AE +Y + +A A + D P PP +++
Sbjct: 7347 ATKLIPNKEYIFRVAAE----NMYGVGEPVQASPITAKYQ---FDPPGPPTRLEPSDITK 7399
Query: 634 DWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVR 693
D + W P DGGSPI GY++ER + +W+R N K+TT+ K + Y R
Sbjct: 7400 DAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFR 7459
Query: 694 IFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLD 750
+ A N G KPS + P + P+ PP TV V T+V + W P+H G A ++
Sbjct: 7460 VLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIE 7519
Query: 751 GYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRV 810
YV+E G+ ++W+ + + T+ + GL + RV
Sbjct: 7520 SYVIEMLKTGT------------------DEWVRVAEG-VPTTQHLLPGLMEGQEYSFRV 7560
Query: 811 KAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRP- 869
+AVN AG SEP S P+L +E + PP PR L+ I + + +P + P
Sbjct: 7561 RAVNKAGESEPSEPSDPVLCREKLYPPS--PPRWLEVINITKNTADLKWTVPEKDGGSPI 7618
Query: 870 -----------ELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKF 918
W+ + + + ++ R A + G+ D
Sbjct: 7619 TNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTE----- 7673
Query: 919 VETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEW 978
+E + + PGPP + + DV +V L W PPK+DG I Y I+K ++ W
Sbjct: 7674 IEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRW 7733
Query: 979 FTVIEHY-HRTSATITELVIGNEYYFRVFSENMCGLSEDATMTK 1021
+ + +T+++ G E F+V +EN G+ + T+
Sbjct: 7734 VKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTE 7777
Score = 162 bits (411), Expect = 1e-39
Identities = 110/364 (30%), Positives = 175/364 (48%), Gaps = 16/364 (4%)
Query: 264 VDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYY 323
V G F EL+ + V+WY G+++ PS K + +G L + + ++ D E
Sbjct: 5710 VTAGETATFDCELSYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQ 5769
Query: 324 VTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIP 383
+TA D K LFV+EPP+ TK LED T G LECEVS ++A VKWFKNG EI+
Sbjct: 5770 LTAKDFKTHANLFVKEPPVEFTKPLEDQTVEEGATAVLECEVSRENAKVKWFKNGTEILK 5829
Query: 384 GPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQT 443
K Y I +G+ L+I T D Y+ ++S L+V ++ L PLTD
Sbjct: 5830 SKK--YEIVADGRVRKLVIHDCTPEDIKTYTCDAKDFKTSCNLNVVPPHVEFLRPLTDLQ 5887
Query: 444 VNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV 502
V + +CE+S EN KW K+G +++ + ++ KG + LVI L +DE +Y
Sbjct: 5888 VREKEMARFECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEY- 5946
Query: 503 FAPDAYNVTLPAKVHVIDPPKII---LDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMW 559
+ + + V++ + L ++ T T+ KL E+ +P + +W
Sbjct: 5947 -SCEVRTARTSGMLTVLEEEAVFTKNLANIEVSETDTI----KLVCEV---SKPGAEVIW 5998
Query: 560 SRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDF 619
+GD+ I+E +GR + LVI A +D+G Y+ L + + + +F
Sbjct: 5999 YKGDEEIIE-TGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEF 6057
Query: 620 PDPP 623
P
Sbjct: 6058 ISKP 6061
Score = 152 bits (383), Expect = 2e-36
Identities = 107/326 (32%), Positives = 162/326 (49%), Gaps = 37/326 (11%)
Query: 519 IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESY 578
+DPP+I +D D T+ V AG +++ I G+P P W +GD+ + + R+ +S
Sbjct: 16041 VDPPRISMDPKYKD-TIVVHAGESFKVDADIYGKPIPTIQWIKGDQEL-SNTARLEIKST 16098
Query: 579 PDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTV-TEVGDDWCI 637
+++L + A R DSG Y + KN AGE ++ VKV+D P PP P V + V + C
Sbjct: 16099 DFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCT 16158
Query: 638 MNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDL----CKETTFEPKKMIEGVAYEVR 693
+ W+PP DGGS I+ Y +ER++ W ++ ++ CK T K++EG Y R
Sbjct: 16159 LAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVT-----KLLEGNEYTFR 16213
Query: 694 IFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLD 750
I AVN G+ +P + S P V P V P V +VT ++ + W P G + +
Sbjct: 16214 IMAVNKYGVGEP-LESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEIL 16272
Query: 751 GYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRV 810
GYVLE + D+ G W +K LI + + +TGL + RV
Sbjct: 16273 GYVLE----------KRDKEGIR--------WTRCHKRLIGELRLRVTGLIENHDYEFRV 16314
Query: 811 KAVNAAGASEPKYYSQPILVKEIIEP 836
A NAAG SEP S P ++ +P
Sbjct: 16315 SAENAAGLSEP---SPPSAYQKACDP 16337
Score = 150 bits (379), Expect = 7e-36
Identities = 100/328 (30%), Positives = 160/328 (48%), Gaps = 26/328 (7%)
Query: 522 PKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS 581
P++ L G+ V AG+ +++EIP+ G P P W +GD+ I++ + R+ E+ S
Sbjct: 14566 PELDLRGI-YQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQ-ILKQTQRVNFETTATS 14623
Query: 582 STLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT-VTEVGDDWCIMNW 640
+ L I+ R DSG Y + +N GE I ++V D P PP P EV D+ +W
Sbjct: 14624 TILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSW 14683
Query: 641 EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAI 700
+PP DGG PI Y +E ++ S+ W+ L + + TT++ ++ G+ Y+ R+ A N
Sbjct: 14684 DPPENDGGVPISNYVVEMRQTDSTTWVELATTVIR-TTYKATRLTTGLEYQFRVKAQNRY 14742
Query: 701 GISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 757
G+ P + S V P V PP V +VT ++T+ W P G + + GY +E
Sbjct: 14743 GVG-PGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVE-- 14799
Query: 758 FEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAG 817
+ + NG W +K L+ F +GL RV A N AG
Sbjct: 14800 --------RKERNGIL--------WQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAG 14843
Query: 818 ASEPKYYSQPILVKEIIEPPKIRIPRHL 845
S+P S+P+L + I+PP +P ++
Sbjct: 14844 KSKPSKPSEPMLALDPIDPPGKPVPLNI 14871
Score = 150 bits (379), Expect = 7e-36
Identities = 103/337 (30%), Positives = 165/337 (48%), Gaps = 25/337 (7%)
Query: 506 DAYNVTLPAKV-HVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDK 564
D + LP + ++PP+I + + +TV V AG+ L+++IPISG+P PK SR D
Sbjct: 19960 DPRELLLPVLIKEQLEPPEIDMKNFPS-HTVYVRAGSNLKVDIPISGKPLPKVTLSR-DG 20017
Query: 565 AIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPV 624
++ + R TE ++ T+ + + D+G Y I N +G A I + V+D P PP
Sbjct: 20018 VPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPT 20077
Query: 625 APTV-TEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKK 683
P V +++ ++ + WEPP YDGGS + Y + +++ ++ W ++ + + T + K
Sbjct: 20078 GPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVAR-TMMKVMK 20136
Query: 684 MIEGVAYEVRIFAVNAIGISK--PSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPP 741
+ G Y+ RI A N GIS S +P PP+ V +VT ++T+ W P
Sbjct: 20137 LTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEP 20196
Query: 742 DHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLP 801
G + + GY LE D N W ANK +I T F +T +
Sbjct: 20197 VSNGGSAVVGYHLE----------MKDRNSIL--------WQKANKLVIRTTHFKVTTIS 20238
Query: 802 TDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPK 838
RV A NAAG +P + S+P+L + EPP+
Sbjct: 20239 AGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACEPPR 20275
Score = 149 bits (377), Expect = 1e-35
Identities = 148/568 (26%), Positives = 234/568 (41%), Gaps = 60/568 (10%)
Query: 360 ELEC-EVSEDDANVKWFK----NGEEII-----------PGPKSRYRIRVEGKKHILIIE 403
ELE +S+D ++W K G+EI+ K + R++ K+ I
Sbjct: 23939 ELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQ--FTIG 23996
Query: 404 GATKADAAEYSVMT---TGGQSSAKLSVDLKPLK-------ILTPLTDQTVNLGKEICLK 453
G +A E+ V TG + ++ +K I + D T LG+ L
Sbjct: 23997 GLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLS 24056
Query: 454 CEI-SENIPG-KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY--VFAPDAYN 509
C+I +P KW + G + +S + K+ GR H L + EDEG Y + +
Sbjct: 24057 CQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGE 24116
Query: 510 VTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEG 569
V +K+ + P+ G G+ LRL + G P P W G K +++
Sbjct: 24117 VETSSKLLLQATPQFH-PGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQK-LLQN 24174
Query: 570 SGRIRTESYPDSSTLVI-DIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTV 628
S I E+ + LV+ ++ + +G Y + L N G A + V++ D PD P P V
Sbjct: 24175 SENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIV 24234
Query: 629 TE-VGDDWCIMNWEPPAYDGGSPILGYFIER-KKKQSSRWMRLNFDLCKETTFEPKKMIE 686
E + + +++W+PPA DGGS I Y +E+ + K+ + W +L TT + E
Sbjct: 24235 IEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEW-QLVSSAISVTTCRIVNLTE 24293
Query: 687 GVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDH 743
Y R+ A N GIS P S + P P T+ +VT + + W+PP
Sbjct: 24294 NAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAWKPPAS 24353
Query: 744 IGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTD 803
G A + Y LE ++ +N WI + I +T F++ L
Sbjct: 24354 DGGAKIRNYYLE--------KREKKQN----------KWISVTTEEIRETVFSVKNLIEG 24395
Query: 804 AKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPF 863
+ RVK N G SE S+PI K + L+ +R A LV
Sbjct: 24396 LEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNA-TLVCKV 24454
Query: 864 QGKPRPELTWKKDGAEIDKNQINIRNSE 891
G P+P + W + G EI + + R E
Sbjct: 24455 TGHPKPIVKWYRQGKEIIADGLKYRIQE 24482
Score = 148 bits (373), Expect = 3e-35
Identities = 104/358 (29%), Positives = 163/358 (45%), Gaps = 33/358 (9%)
Query: 491 ANALTEDEGDYVFAPDAYNVT---LPAKVHVIDPPKIILDGLDA----DNTVTVIAGNKL 543
A LTE + +Y F A N P+++ V+ ++ LD D +
Sbjct: 13445 AKDLTEGK-EYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNF 13503
Query: 544 RLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKN 603
RL+IPI G+P P W +G+ + + R+ ES ++TL++ ++ D+G Y I LKN
Sbjct: 13504 RLKIPIKGKPAPSVSWKKGEDPLATDT-RVSVESSAVNTTLIVYDCQKSDAGKYTITLKN 13562
Query: 604 EAGEAHASIKVKVVDFPDPPVAPT-VTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQ 662
AG +I +KVV P P P EV + + W PP DGGS I Y +E++
Sbjct: 13563 VAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSV 13622
Query: 663 SSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTS 719
+++W+ ++TTF ++ EG+ Y R+ A N G+ + + S P V P V
Sbjct: 13623 NNKWVTCA-SAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGE-GLKSEPIVARHPFDVPD 13680
Query: 720 PPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPA 779
P + V +V++ W P G + + GY LE+ S
Sbjct: 13681 APPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLL---------------- 13724
Query: 780 EDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPP 837
W ANK I F +TGL + RV A+N AG +P S+P++ + I+PP
Sbjct: 13725 --WKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPP 13780
Score = 145 bits (365), Expect = 3e-34
Identities = 110/374 (29%), Positives = 173/374 (46%), Gaps = 19/374 (5%)
Query: 263 QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 322
QV + RF EL+ +VKW+K+G EI+ KY KG RIL IN C + D++EY
Sbjct: 5887 QVREKEMARFECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEY 5946
Query: 323 YVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEII 382
+ S L V E + TK L + + ++L CEVS+ A V W+K EEII
Sbjct: 5947 SCEVRTARTSGMLTVLEEEAVFTKNLANIEVSETDTIKLVCEVSKPGAEVIWYKGDEEII 6006
Query: 383 PGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQ 442
RY I EG+K IL+I+ A DA Y+ ++ K+ V + ++ +
Sbjct: 6007 --ETGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNL 6064
Query: 443 TVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 501
+ G++ C IS E+ P +W ++ ++ D+ V+ G+ LV+ +A +D G Y
Sbjct: 6065 EILEGEKAEFVCSISKESFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTY 6124
Query: 502 VF----APDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKA 557
V A A ++T+ K+ ++ P K D V E+ G KA
Sbjct: 6125 VVMVGAARAAAHLTVIEKLRIVVPLK--------DTRVKEQQEVVFNCEVNTEG---AKA 6173
Query: 558 MWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVV 617
W R ++AI + S I + TL I A DD Y+++L N GE S +V
Sbjct: 6174 KWFRNEEAIFDSSKYIILQK-DLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSAANLIV 6232
Query: 618 DFPDPPVAPTVTEV 631
+ D + + ++
Sbjct: 6233 EEEDLRIVEPLKDI 6246
Score = 143 bits (360), Expect = 1e-33
Identities = 99/322 (30%), Positives = 145/322 (45%), Gaps = 23/322 (7%)
Query: 519 IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESY 578
ID P LD D + V AG LE I G+P P +WS+ K + E + R+ +S
Sbjct: 18205 IDAPNASLDPKYKD-VIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKST 18263
Query: 579 PDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT-VTEVGDDWCI 637
+TLV+ R D G Y + L N G I VKV+D P PP P VT V + C
Sbjct: 18264 IQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCY 18323
Query: 638 MNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAV 697
+ W PP DGG+ I Y IE+++ W +++ ++ + ++ K++ G Y R+ AV
Sbjct: 18324 LAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEV-QALNYKVTKLLPGNEYIFRVMAV 18382
Query: 698 NAIGISKP--SMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLE 755
N GI +P S P P PP+ V ++T ++ + W P G ++GY+LE
Sbjct: 18383 NKYGIGEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILE 18442
Query: 756 YCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNA 815
+ D+ G W NK + + +TGL RV A NA
Sbjct: 18443 ----------KRDKEGVR--------WTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENA 18484
Query: 816 AGASEPKYYSQPILVKEIIEPP 837
AG EP S + + PP
Sbjct: 18485 AGVGEPSEPSVFYRACDALYPP 18506
Score = 140 bits (352), Expect = 9e-33
Identities = 97/357 (27%), Positives = 171/357 (47%), Gaps = 39/357 (10%)
Query: 496 EDEGDYVF---APDAYNVTLPAK----VHVID---PPKIILDGLDADNTVTVIAGNKLRL 545
E++ Y F A A N++ P++ V ++ PP+I L + + +TV AG + L
Sbjct: 12760 EEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLS-VAMKSLLTVKAGTNVCL 12818
Query: 546 EIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEA 605
+ + G+P P W + D +++ + I+ + TL + R DSG Y I +N +
Sbjct: 12819 DATVFGKPMPTVSWKK-DGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSS 12877
Query: 606 GEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSR 665
G A+IK+KV+D P PP + + ++ D +++WEPP DGGS I Y +++++
Sbjct: 12878 GSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPN 12937
Query: 666 WMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGI-----SKPSMPSRPFVPLAVTSP 720
W +++ + T+ +K+IEG Y+ RI A N G+ ++P++ P+ P P
Sbjct: 12938 WAQVSATV-PITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDP 12996
Query: 721 PTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAE 780
P + ++T +T+ W+PP G + + GY+LE + A
Sbjct: 12997 P---VISNITKDHMTVSWKPPADDGGSPITGYLLE------------------KRETQAV 13035
Query: 781 DWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPP 837
+W N+ I + TGL + RV A+N AG +P S+ ++ PP
Sbjct: 13036 NWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPP 13092
Score = 139 bits (350), Expect = 2e-32
Identities = 112/414 (27%), Positives = 188/414 (45%), Gaps = 21/414 (5%)
Query: 270 VRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDE 329
+ F V + + KW KNG EI+ + K K L I N D ++Y AG
Sbjct: 2940 ITFEVTVNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKA 2999
Query: 330 KCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRY 389
+ L+V I K ++D +R ECEVSE D V+W K+ +E+ R
Sbjct: 3000 TSTATLYVEARHIEFRKHIKDIKVLEKKRAMFECEVSEPDITVQWMKDDQEL--QITDRI 3057
Query: 390 RIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKE 449
+I+ E H L+I +DA +Y+V+ G S+AKL V+ + ++I + + V +
Sbjct: 3058 KIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEKQR 3117
Query: 450 ICLKCEISE-NIPGKWTKNGLPV--QESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPD 506
++ E++E ++ W K+G+ + Q +R K V + RIH++ I+ D G+Y F
Sbjct: 3118 AVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAG 3177
Query: 507 AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAI 566
++ V+ +PP++ L VTV +G R ISG P PK W + ++ +
Sbjct: 3178 RNRSSVTLYVNAPEPPQV----LQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLL 3233
Query: 567 MEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG----EAHASIKVKVVDFPD- 621
G + + TL++ A +D+ VY KN+ G A S++V V PD
Sbjct: 3234 STGF-KCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQ 3292
Query: 622 --PPVAPTVTEVGDDWCIMNWEPPAY----DGGSPILGYFIERKKKQSSRWMRL 669
P P + D +P + G + ++ + KK + SR+ R+
Sbjct: 3293 EMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRM 3346
Score = 137 bits (344), Expect = 8e-32
Identities = 104/360 (28%), Positives = 172/360 (47%), Gaps = 10/360 (2%)
Query: 272 FVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKC 331
F VEL+ + VKW+KN Q + + + +G + + + D S+ V A
Sbjct: 5451 FTVELSHDNIRVKWFKNDQRLHTTRSVSMQDEGKTHSITFKDLSIDDTSQIRVEAMGMSS 5510
Query: 332 STELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRI 391
+L V E T +L+D T + V L+CE+S+ DA VKWFK+G+EI P + I
Sbjct: 5511 EAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISKADAPVKWFKDGKEIKPSKNA--VI 5568
Query: 392 RVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEIC 451
+ +GKK +LI++ A K+D +Y+ ++S KL ++ + +K++ PL V +
Sbjct: 5569 KADGKKRMLILKKALKSDIGQYTCDCGTDKTSGKLDIEDREIKLVRPLHSVEVMETETAR 5628
Query: 452 LKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNV 510
+ EISE +I W G + ++ ++ +G+IH LV+ N + G F A NV
Sbjct: 5629 FETEISEDDIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTGGVDF--QAANV 5686
Query: 511 TLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGS 570
A + V P++I L VTV AG + +S E P + +G K +E S
Sbjct: 5687 KSSAHLRV--KPRVI-GLLRPLKDVTVTAGETATFDCELSYEDIPVEWYLKGKK--LEPS 5741
Query: 571 GRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTE 630
++ S TL + + +D+G + K+ A+ +K V+F P TV E
Sbjct: 5742 DKVVPRSEGKVHTLTLRDVKLEDAGEVQLTAKDFKTHANLFVKEPPVEFTKPLEDQTVEE 5801
Score = 137 bits (344), Expect = 8e-32
Identities = 134/554 (24%), Positives = 209/554 (37%), Gaps = 88/554 (15%)
Query: 617 VDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKE 676
+D P PP PTV +VG +NW P +DGG+ I Y IE K + W+R+ +
Sbjct: 7484 IDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTT 7543
Query: 677 TTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTT 733
P M EG Y R+ AVN G S+PS PS P + L SPP L V ++T T
Sbjct: 7544 QHLLPGLM-EGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNT 7602
Query: 734 VTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKT 793
++W P+ G + + Y++E D+ + W + + D T
Sbjct: 7603 ADLKWTVPEKDGGSPITNYIVE------------------KRDVRRKGWQTVDTTVKD-T 7643
Query: 794 KFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRV 853
K T+T L + RV A NA G S+ +L K+ P
Sbjct: 7644 KCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTP---------------- 7687
Query: 854 GEAVNLVIPFQGKPRPELTW---KKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYD 910
G L + K +L W K DG + + + T R + + D
Sbjct: 7688 GPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGT----RWVKAGKTAGPD 7743
Query: 911 LQVKVDKFVETASIDIQI-----------------------IDRPGPPQIVKIEDVWGEN 947
+V +E + Q+ P PP + + D ++
Sbjct: 7744 CNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKH 7803
Query: 948 VALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITE--LVIGNEYYFRV 1005
+A+ W PP+ +G + I GY ++ + +W V + E +V EY RV
Sbjct: 7804 IAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRV 7863
Query: 1006 FSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNAT 1065
+ N G+SE + +++ V+A+D E D I G +
Sbjct: 7864 RAVNAIGVSEPSEISEN--VVAKDPDCKPTIDLETHDI-------------IVIEGEKLS 7908
Query: 1066 LNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDL 1125
+ R P P ++W K+ + R M ++ LE+ K D G Y N L
Sbjct: 7909 IPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKL 7968
Query: 1126 GTVEIECKLEVKVI 1139
G+ + VKVI
Sbjct: 7969 GSA--TASINVKVI 7980
Score = 136 bits (343), Expect = 1e-31
Identities = 105/376 (27%), Positives = 169/376 (44%), Gaps = 13/376 (3%)
Query: 247 EEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQ 306
+ K+ F + L +K F E ++P ++VKWYK+G E+ KY
Sbjct: 2123 QAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKV 2182
Query: 307 RILFINNCQMTDDSEY-YVTAGDE--KCSTELFVREPPIMVTKQLEDTTAYCGERVELEC 363
L I +D +Y V DE K + +L V + K+L+D ELEC
Sbjct: 2183 HFLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGELEC 2242
Query: 364 EVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSS 423
VS ++ KW+ N E+ +Y I + L ++ TK D EYS + G +++
Sbjct: 2243 IVSPENIEGKWYHNDVEL--KSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTT 2300
Query: 424 AKLSVDLKPLKILTPLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKVVHK 482
KL + +P+ IL L+DQ V G + L+ ++S E++ G W K+G VQ SDR+ +V
Sbjct: 2301 CKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVID 2360
Query: 483 GRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNK 542
+ H L+I + ED G+Y F A ++ +V V +D + V VI G K
Sbjct: 2361 KQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYS-----VDVITPLKDVNVIEGTK 2415
Query: 543 LRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLK 602
LE +S W D+ I + R++ LVI+ D G Y + +
Sbjct: 2416 AVLECKVSVPDVTSVKWYLNDEQI-KPDDRVQAIVKGTKQRLVINRTHASDEGPYKLIVG 2474
Query: 603 NEAGEAHASI-KVKVV 617
+ S+ K+K++
Sbjct: 2475 RVETNCNLSVEKIKII 2490
Score = 133 bits (335), Expect = 8e-31
Identities = 197/836 (23%), Positives = 326/836 (38%), Gaps = 110/836 (13%)
Query: 337 VREPPIMVTKQLEDTTAY-CGERVELECEVS-EDDANVKWFKNGEEIIPGPKSRYRIRVE 394
V P I V + +DT GE LE +VS ++W K+G+E+ ++ I++
Sbjct: 14959 VEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKEL--EGTAKLEIKIA 15016
Query: 395 GKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKC 454
L+ + +T+ D+ Y++ T AK ++K L P + + + + KC
Sbjct: 15017 DFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGP-PEGPLAVTEVTSEKC 15075
Query: 455 EISENIP-----GKWTKNGLPVQESDRL---KVVHKGRIHKLVIANALTEDEGDY-VFAP 505
+S P K + +E+ RL V + ++ KL + L +E + V A
Sbjct: 15076 VLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAV 15135
Query: 506 DAYNVTLPAKVHVI---------DPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPK 556
+ Y V P + + DPPK + VT I + + + G P
Sbjct: 15136 NKYGVGEPLESEPVLAVNPYGPPDPPK--------NPEVTTITKDSM---VVCWGHPDSD 15184
Query: 557 A-------MWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG--- 606
+ R DKA + ++ D V + E + + I +N AG
Sbjct: 15185 GGSEIINYIVERRDKAGQRWI-KCNKKTLTDLRYKVSGLTEGHEYE-FRIMAENAAGISA 15242
Query: 607 EAHASIKVKVVDF---PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQS 663
+ S K D P PP P V + + W P YDGGS I GY +E +
Sbjct: 15243 PSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEE 15302
Query: 664 SRWMRLNFDL-CKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSM-PSRPFVPLAVTSPP 721
W + K T++ + E Y++RI+A+N+ G+ +P++ P P + P
Sbjct: 15303 DEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPE 15362
Query: 722 TLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAED 781
L D T+ + G +++ + S ++ ++Y L
Sbjct: 15363 IELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESLDKASIESTSSYTL---- 15418
Query: 782 WIVANKDLIDKTKF--TITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEII----- 834
IV N + D K+ T+ FV V+ ++ G Q + VKE+
Sbjct: 15419 LIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPP------QDLKVKEVTKTSVT 15472
Query: 835 ---EPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSE 891
+PP + +K YI E+ + +WK D + E
Sbjct: 15473 LTWDPPLLDGGSKIKN-YIVEKRESTRKAYSTVATNCHKTSWKVDQLQ-----------E 15520
Query: 892 TDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALT 951
+ F AE + + ETA ++ +RP PP + + DV +V+L+
Sbjct: 15521 GCSYYFRVLAENEYG--------IGLPAETAE-SVKASERPLPPGKITLMDVTRNSVSLS 15571
Query: 952 WTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMC 1011
W P+ DG + I GY ++ K S +W T T ATIT L+ G EY FRV ++N
Sbjct: 15572 WEKPEHDGGSRILGYIVEMQTKGSDKWATCAT-VKVTEATITGLIQGEEYSFRVSAQNEK 15630
Query: 1012 GLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI-AGYNATLNCSV 1070
G+S+ ++ VIA+D I P + L NT+ + AG + ++
Sbjct: 15631 GISDPRQLSVP--VIAKDLVI--------------PPAFKLLFNTFTVLAGEDLKVDVPF 15674
Query: 1071 RGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLG 1126
G P P +TW K+ V + R S + L I+ D G Y K N G
Sbjct: 15675 IGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAG 15730
Score = 133 bits (335), Expect = 8e-31
Identities = 89/320 (27%), Positives = 152/320 (47%), Gaps = 26/320 (8%)
Query: 522 PKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS 581
P L G+ + +T AG+ +++PISG P PK W + + E + R+ + D
Sbjct: 22148 PTADLTGI-TNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKE-TDRVSITTTKDR 22205
Query: 582 STLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT-VTEVGDDWCIMNW 640
+TL + + R DSG Y + L+N AG S+ V V+ P P P V+ V + C+++W
Sbjct: 22206 TTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLSW 22265
Query: 641 EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAI 700
P GG+ I Y +E+++ ++ W +N + K T + + + + Y R+ + N
Sbjct: 22266 GEPKDGGGTEITNYIVEKRESGTTAWQLVNSSV-KRTQIKVTHLTKYMEYSFRVSSENRF 22324
Query: 701 GISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 757
G+SKP + S P + P S PT V V+ +++RW P H G + + GY +E
Sbjct: 22325 GVSKP-LESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVE-- 22381
Query: 758 FEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAG 817
+ + N W+ NK + + +TGL + R A+NAAG
Sbjct: 22382 --------KKERNTIL--------WVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAG 22425
Query: 818 ASEPKYYSQPILVKEIIEPP 837
S+ S+PI+ + ++ P
Sbjct: 22426 VSKASEASRPIMAQNPVDAP 22445
Score = 131 bits (329), Expect = 4e-30
Identities = 159/630 (25%), Positives = 262/630 (41%), Gaps = 95/630 (15%)
Query: 267 GGRVRFVVELAD-PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVT 325
GG +R V + P EVKW K EIR + I + L ++N D +Y +T
Sbjct: 16460 GGSLRLFVPIKGRPTPEVKWGKVDGEIRDAA--IIDVTSSFTSLVLDNVNRYDSGKYTLT 16517
Query: 326 AGDEKCSTELFVR-------EPPI--MVTKQLEDTTAYCGERVELECE-------VSEDD 369
+ + FV PP+ VT+ +D+ + E L+ V + +
Sbjct: 16518 LENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKRE 16577
Query: 370 ANVKWF--------KNG---EEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTT 418
A K + KN +++ G +R+ E + I A A+ +
Sbjct: 16578 ATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGI-----GLPAQTADPIKVAE 16632
Query: 419 GGQSSAKLSVDLKPLKILTPLTDQTVNLG---KEICLKCEISENIPGKWTKNGLPVQESD 475
Q K++VD +T +V+L E +I + I K+ E
Sbjct: 16633 VPQPPGKITVD--------DVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECA 16684
Query: 476 RLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYN-----------VTLPAKVHVIDPPKI 524
R+K + + VI N LT+ E +Y+F A N V + AK VI+P
Sbjct: 16685 RVKSL------QAVITN-LTQGE-EYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEP--- 16733
Query: 525 ILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTL 584
D A ++ +V G L++E+PISG P P W++ D ++ + RI D +TL
Sbjct: 16734 --DVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTK-DGLPLKQTTRINVTDSLDLTTL 16790
Query: 585 VIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT-VTEVGDDWCIMNWEPP 643
I +DD G Y I + N G+ ASI++ +D PDPP P +V + ++W PP
Sbjct: 16791 SIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPP 16850
Query: 644 AYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGIS 703
Y GG I Y ++++ ++ W ++ + + TT + K+ G Y+ RIFA N G S
Sbjct: 16851 LYTGGCQITNYIVQKRDTTTTVWDVVSATVAR-TTLKVTKLKTGTEYQFRIFAENRYGQS 16909
Query: 704 KPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEG 760
++ S P V P PP +++ ++ ++W P + G + + GY LE
Sbjct: 16910 F-ALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLE----- 16963
Query: 761 STSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASE 820
+ + N W NK +I T+F L + RV A N G +
Sbjct: 16964 -----RKERNSIL--------WTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGK 17010
Query: 821 PKYYSQPILVKEIIEPPKIRIPRHLKQTYI 850
S+ + ++ +PP P +K+ I
Sbjct: 17011 ASKNSECYVARDPCDPPGTPEPIMVKRNEI 17040
Score = 131 bits (329), Expect = 4e-30
Identities = 92/316 (29%), Positives = 146/316 (46%), Gaps = 25/316 (7%)
Query: 521 PPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPD 580
PPK LD + VT+ AG+ L L+ + G+P PK +W++GDK ++ ++ +
Sbjct: 22546 PPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKE-LDLCEKVSLQYTGK 22604
Query: 581 SSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNW 640
+T VI +R DSG Y + +KN +G S+ VKV+D P P TV+ V + C + W
Sbjct: 22605 RATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAW 22664
Query: 641 EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAI 700
P DGG+ I Y +ER++ W+ + + C ++ ++I+ Y R+ AVN
Sbjct: 22665 SLPQEDGGAEITHYIVERRETSRLNWVIVEGE-CPTLSYVVTRLIKNNEYIFRVRAVNKY 22723
Query: 701 GISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 757
G P + S P V + SPP + + ++W P+ G + Y+++
Sbjct: 22724 GPGVP-VESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKR 22782
Query: 758 FEGSTSAKQSDENGEAAYDLPAEDWIVANKD-LIDKTKFTITGLPTDAKIFVRVKAVNAA 816
+ S W NKD ++ T+ +T L RV AVNAA
Sbjct: 22783 EKKSLR------------------WTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAA 22824
Query: 817 GASEPKYYSQPILVKE 832
G SEP S I +E
Sbjct: 22825 GNSEPSEASNFISCRE 22840
Score = 130 bits (328), Expect = 5e-30
Identities = 80/234 (34%), Positives = 120/234 (51%), Gaps = 8/234 (3%)
Query: 272 FVVELADPKLE-VKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEK 330
F VEL P ++ V+W KNG + + KY KG L I NC + D+S Y G
Sbjct: 2680 FTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGFRLGRLG 2739
Query: 331 CSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYR 390
S L V + + K+ +D TA V E VS D VKWF EI P K +R
Sbjct: 2740 ASARLHVET--VKIIKKPKDVTALENATVAFEVSVSHDTVPVKWFHKSVEIKPSDK--HR 2795
Query: 391 IRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEI 450
+ E K H L+++ + +DA EY+ + GQ K + ++ L I + + V K
Sbjct: 2796 LVSERKVHKLMLQNISPSDAGEYTAVV--GQLECKAKLFVETLHITKTMKNIEVPETKTA 2853
Query: 451 CLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF 503
+CE+S N+P W KNG+ ++ S++ K+V +G++H+L+I N TED +Y F
Sbjct: 2854 SFECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTF 2907
Score = 130 bits (328), Expect = 5e-30
Identities = 91/320 (28%), Positives = 147/320 (45%), Gaps = 24/320 (7%)
Query: 522 PKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS 581
P I+ G + + + + +G LR++ + G P P+ W + D +E + S
Sbjct: 21458 PPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFK-DGVEIEKRMNMEITDVLGS 21516
Query: 582 STLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT-VTEVGDDWCIMNW 640
++L + A RD GVY + KN +G A A IKVKV D P V P T + + + W
Sbjct: 21517 TSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWW 21576
Query: 641 EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAI 700
+ P DG +PI Y IE+++ W + D C+ ++ K+I G Y+ R+ AVN
Sbjct: 21577 DAPLNDGCAPITHYIIEKRETSRLAWALIE-DKCEAQSYTAIKLINGNEYQFRVSAVNKF 21635
Query: 701 GISKP--SMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCF 758
G+ +P S P + V P + ++T ++T+ W P+ G + + Y+LE
Sbjct: 21636 GVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERRE 21695
Query: 759 EGSTSAKQSDENGEAAYDLPAEDWI-VANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAG 817
+ ST W+ V +K I +T+F +TGL + V A NAAG
Sbjct: 21696 KKSTR------------------WVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAG 21737
Query: 818 ASEPKYYSQPILVKEIIEPP 837
S+ I +E + PP
Sbjct: 21738 VGPASGISRLIKCREPVNPP 21757
Score = 128 bits (322), Expect = 3e-29
Identities = 101/352 (28%), Positives = 164/352 (46%), Gaps = 15/352 (4%)
Query: 264 VDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYY 323
V +G FV EL+ K+ V W+KN ++ S + +G L + + D S+
Sbjct: 5088 VKEGETATFVCELSHEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIK 5147
Query: 324 VTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIP 383
+ + +L V E T +L D TA + + L+CEVS+ D VKWFK+GEEI+P
Sbjct: 5148 AQVKELSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSK-DVPVKWFKDGEEIVP 5206
Query: 384 GPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQT 443
PK Y I+ +G + IL I+ A D EY ++ A ++V+ + +K+ PL
Sbjct: 5207 SPK--YSIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPLYGVE 5264
Query: 444 VNLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV 502
V +G+ + E+SE ++ G+W G P+ S +++ G+ H L++ N G+
Sbjct: 5265 VFVGETAHFEIELSEPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTGEVS 5324
Query: 503 FAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRG 562
F A N A + V + P I + L + V V ++ + E +S E P W +G
Sbjct: 5325 F--QAANAKSAANLKVKELPLIFITPL---SDVKVFEKDEAKFECEVSRE-PKTFRWLKG 5378
Query: 563 DKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKV 614
+ I G R ++VI A +D Y EA + H S K+
Sbjct: 5379 TQEI-TGDDRFELIKDGTKHSMVIKSAAFEDEAKYMF----EAEDKHTSGKL 5425
Score = 127 bits (319), Expect = 6e-29
Identities = 199/857 (23%), Positives = 322/857 (37%), Gaps = 121/857 (14%)
Query: 319 DSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAY-CGERVELECEV-SEDDANVKWFK 376
DS +TA DE V P I + + DT GE LE +V + ++W +
Sbjct: 17112 DSTGPITAKDE-------VELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLR 17164
Query: 377 NGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKIL 436
+EI +R I+ K +LI++ A + D +Y + + S V++K L
Sbjct: 17165 GDKEI--EESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRP 17222
Query: 437 TPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVVHKGRIHKL-------- 488
P + V + KC ++ + P + G + VV K +L
Sbjct: 17223 GP-PEGPVQVTGVTSEKCSLTWSPPLQ--DGGSDISHY----VVEKRETSRLAWTVVASE 17275
Query: 489 VIANALTEDE----GDYVF---APDAYNVTLPAK-VHVIDPPKIILDGLDADNTVTVIAG 540
V+ N+L + +YVF A + Y V P + V+ +L G VT IA
Sbjct: 17276 VVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAK 17335
Query: 541 NKLRLEIPISGEPPPKAMWSRGDKA--------IMEGSGRIRTESYPDSSTLVIDIAER- 591
+ + + W+R D I+E R + + D+ R
Sbjct: 17336 DSMTV------------CWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRV 17383
Query: 592 -----DDSGVYHINLKNEAGEAH---ASIKVKVVD---FPDPPVAPTVTEVGDDWCIMNW 640
D + ++ +N AG A++ K D P PP + + + + W
Sbjct: 17384 TGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAW 17443
Query: 641 EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDL-CKETTFEPKKMIEGVAYEVRIFAVNA 699
P YDGGS ILGY +E K W + + T FE K+ E Y++R+ A+N
Sbjct: 17444 GKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNK 17503
Query: 700 IGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFE 759
+G+ + + P P L +DS + +R A G + +
Sbjct: 17504 VGLGEATSVPGTVKPEDKLEAPEL-DLDSELRKGIVVR--------AGGSARIHIPFKGR 17554
Query: 760 GSTSAKQSDENGEAAYDLPAEDWI------VANKDLIDKTKFTIT--GLPTDAKIFVRVK 811
+ S E GE + E + + N D D K+ + FV VK
Sbjct: 17555 PTPEITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVK 17614
Query: 812 AVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPEL 871
++ G Q + VKE+ + + + I + N VI + R
Sbjct: 17615 VLDTPGPP------QNLAVKEVRKDSAFLV---WEPPIIDGGAKVKNYVIDKRESTRK-- 17663
Query: 872 TWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDR 931
+ ++ K + N I + R + G V VET ++ +
Sbjct: 17664 AYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFG-------VGVPVETVDA-VKAAEP 17715
Query: 932 PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSAT 991
P PP V + DV + +L W P+ DG + + GY ++ K + +W V E +A
Sbjct: 17716 PSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAES-KVCNAV 17774
Query: 992 ITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQ 1051
+T L G EY FRV + N G S+ + VIA+D I P
Sbjct: 17775 VTGLSSGQEYQFRVKAYNEKGKSDPRVLGVP--VIAKDLTIQ-------------PSLKL 17819
Query: 1052 PLVNTYAI-AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPS 1110
P NTY+I AG + + V G P+P I+W+K+ + R + L I++ +
Sbjct: 17820 PF-NTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGN 17878
Query: 1111 PYDGGTYCCKAVNDLGT 1127
D G Y A N GT
Sbjct: 17879 KDDFGKYTVTATNSAGT 17895
Score = 126 bits (316), Expect = 1e-28
Identities = 125/552 (22%), Positives = 221/552 (40%), Gaps = 66/552 (11%)
Query: 597 YHINLKNEAG---EAHASIKVKVVD---FPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSP 650
Y + +N AG + S ++ D P PP P + + G + W P +DGG+P
Sbjct: 19558 YRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAP 19617
Query: 651 ILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSR 710
I GY +E KK + W + + + T + + G Y R+ +VN +G S PS S
Sbjct: 19618 ITGYTVEYKKSDDTDW-KTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSD 19676
Query: 711 PFVPLAVTSPP----------TLLTVDSVTDT-TVTMRWRPPDHIGAAGLDGYVLEYCFE 759
P + P TL+ + T TV R RP ++ + D + +
Sbjct: 19677 PQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYV 19736
Query: 760 GSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGAS 819
+T ++ S L E+ AN++ K TI + + A + + VK ++ G
Sbjct: 19737 DTTDSRTS---------LTIEN---ANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGPP 19784
Query: 820 EPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAE 879
I V+++ + + L G A + + + W
Sbjct: 19785 TN------ITVQDVTKESAV-----LSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNN 19833
Query: 880 IDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVK 939
++ + N + I + R SG+ + V + ET ++I ++P PP+ +
Sbjct: 19834 CNRLSYKVTNLQEGAIYYFRV-----SGENEFGVGIP--AETKE-GVKITEKPSPPEKLG 19885
Query: 940 IEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF--TVIEHYHRTSATITELVI 997
+ + ++V+LTW P+ DG + I Y ++ +K W V + H + + E
Sbjct: 19886 VTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKCAVAKSTHHVVSGLRE--- 19942
Query: 998 GNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTY 1057
+EY+FRVF+EN GLS+ + + + E + E M P Y
Sbjct: 19943 NSEYFFRVFAENQAGLSDPREL------------LLPVLIKEQLEPPEIDMKNFPSHTVY 19990
Query: 1058 AIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTY 1117
AG N ++ + G P PK+T ++ V + R+ T+ +++ D G Y
Sbjct: 19991 VRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRY 20050
Query: 1118 CCKAVNDLGTVE 1129
A N GT +
Sbjct: 20051 EITAANSSGTTK 20062
Score = 125 bits (315), Expect = 2e-28
Identities = 87/266 (32%), Positives = 123/266 (46%), Gaps = 11/266 (4%)
Query: 247 EEKKSAAFAKIL--DPAYQV---DKGGRVRFVVEL---ADPKLEVKWYKNGQEIRPSTKY 298
+E S A K+L DP + V DK + + L + VKW+K+G+EI PS KY
Sbjct: 5151 KELSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSKDVPVKWFKDGEEIVPSPKY 5210
Query: 299 IFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGER 358
+ G +RIL I + D EY G +K + V I V K L + GE
Sbjct: 5211 SIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPLYGVEVFVGET 5270
Query: 359 VELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTT 418
E E+SE D + +W G+ + P I +GKKHILI+ E S
Sbjct: 5271 AHFEIELSEPDVHGQWKLKGQPLTASPDC--EIIEDGKKHILILHNCQLGMTGEVSFQAA 5328
Query: 419 GGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRL 477
+S+A L V PL +TPL+D V E +CE+S E +W K + DR
Sbjct: 5329 NAKSAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPKTFRWLKGTQEITGDDRF 5388
Query: 478 KVVHKGRIHKLVIANALTEDEGDYVF 503
+++ G H +VI +A EDE Y+F
Sbjct: 5389 ELIKDGTKHSMVIKSAAFEDEAKYMF 5414
Score = 124 bits (312), Expect = 4e-28
Identities = 135/548 (24%), Positives = 203/548 (37%), Gaps = 95/548 (17%)
Query: 620 PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDL-CKETT 678
P PP P V + ++W PAYDGGSPI+GY +E K+ S W+R N ++T
Sbjct: 13092 PGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTR 13151
Query: 679 FEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPP----------TLLTVDS 728
FE ++E Y+ R++AVN IG S PS P + PP TL+
Sbjct: 13152 FEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAG 13211
Query: 729 VTDTT-VTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANK 787
VT V ++ RPP P W N
Sbjct: 13212 VTMRLYVPVKGRPP------------------------------------PKITWSKPNV 13235
Query: 788 DLIDKTKFTITGLPTDAKIFVRVKAVNAAGASE----------PKYYSQPILVKEIIEPP 837
+L D+ I TD F+R + VN A + K Y+ + V + PP
Sbjct: 13236 NLRDRIGLDIKS--TDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPP 13293
Query: 838 -KIRIPRHLKQT--------YIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIR 888
+ + K + I +N V+ Q + +W E K +
Sbjct: 13294 VNVTVKEISKDSAYVTWEPPIIDGGSPIINYVV--QKRDAERKSWSTVTTECSKTSFRVA 13351
Query: 889 NSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENV 948
N E F R + G D D ++ PGP +K+ V +
Sbjct: 13352 NLEEGKSYFFRVFAENEYGIGDPGETRDA--------VKASQTPGPVVDLKVRSVSKSSC 13403
Query: 949 ALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSE 1008
++ W P DG + I GY + +++ +W V++ + +L G EY FRV +E
Sbjct: 13404 SIGWKKPHSDGGSRIIGYVVDFLTEEN-KWQRVMKSLS-LQYSAKDLTEGKEYTFRVSAE 13461
Query: 1009 NMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNC 1068
N G + +T V+ARD + V D D P A N L
Sbjct: 13462 NENGEGTPSEIT----VVARD-----DVVAPDLDLKGLPDLCY-----LAKENSNFRLKI 13507
Query: 1069 SVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTV 1128
++G P P ++W K + + D R + S+ TL + D G Y N GT
Sbjct: 13508 PIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTK 13567
Query: 1129 EIECKLEV 1136
E ++V
Sbjct: 13568 EGTISIKV 13575
Score = 120 bits (301), Expect = 7e-27
Identities = 130/513 (25%), Positives = 208/513 (40%), Gaps = 41/513 (7%)
Query: 96 KGKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSF 155
KG+W+ + GKHL L S + + I K + G Y TYK S
Sbjct: 2603 KGEWL----RDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEY----TYKVATSKTSA 2654
Query: 156 DLEVH--ESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWEL 213
L+V + T N+ + + + +K V + E+ + V
Sbjct: 2655 KLKVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISV--- 2711
Query: 214 LKNAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVD--KGGRVR 271
K + Y I D RL R+ + KI+ V + V
Sbjct: 2712 ----KGTIYSLRIKNCAIVDESVYGFRLGRLGASARLHVETVKIIKKPKDVTALENATVA 2767
Query: 272 FVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKC 331
F V ++ + VKW+ EI+PS K+ + L + N +D EY G +C
Sbjct: 2768 FEVSVSHDTVPVKWFHKSVEIKPSDKHRLVSERKVHKLMLQNISPSDAGEYTAVVGQLEC 2827
Query: 332 STELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRI 391
+LFV + +TK +++ + ECEVS + W KNG EI K ++I
Sbjct: 2828 KAKLFVE--TLHITKTMKNIEVPETKTASFECEVSHFNVPSMWLKNGVEIEMSEK--FKI 2883
Query: 392 RVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEIC 451
V+GK H LII + D+AEY+ + Q SA L+V P+ I + L D +N ++
Sbjct: 2884 VVQGKLHQLIIMNTSTEDSAEYTFVCGNDQVSATLTV--TPIMITSMLKD--INAEEKDT 2939
Query: 452 LKCEISENIPG---KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPD-- 506
+ E++ N G KW KNG+ ++ +D+ ++ K H L I N D DY F
Sbjct: 2940 ITFEVTVNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKA 2999
Query: 507 AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAI 566
TL + I+ K I D + V+ + E +S EP W + D+
Sbjct: 3000 TSTATLYVEARHIEFRKHIKD-------IKVLEKKRAMFECEVS-EPDITVQWMKDDQE- 3050
Query: 567 MEGSGRIRTESYPDSSTLVIDIAERDDSGVYHI 599
++ + RI+ + L+I D+G Y +
Sbjct: 3051 LQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTV 3083
Score = 120 bits (301), Expect = 7e-27
Identities = 89/317 (28%), Positives = 143/317 (45%), Gaps = 11/317 (3%)
Query: 256 KILDPAYQVD--KGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINN 313
K++ P + V+ + RF E+++ + W G+ + + + +G L ++N
Sbjct: 5611 KLVRPLHSVEVMETETARFETEISEDDIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHN 5670
Query: 314 CQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVK 373
C++ A + K S L V+ I + + L+D T GE +CE+S +D V+
Sbjct: 5671 CRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCELSYEDIPVE 5730
Query: 374 WFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPL 433
W+ G+++ P K R EGK H L + DA E + ++ A L V P+
Sbjct: 5731 WYLKGKKLEPSDK--VVPRSEGKVHTLTLRDVKLEDAGEVQLTAKDFKTHANLFVKEPPV 5788
Query: 434 KILTPLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIAN 492
+ PL DQTV G L+CE+S EN KW KNG + +S + ++V GR+ KLVI +
Sbjct: 5789 EFTKPLEDQTVEEGATAVLECEVSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHD 5848
Query: 493 ALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGE 552
ED Y DA + ++V+ P L L + V R E +S E
Sbjct: 5849 CTPEDIKTYTC--DAKDFKTSCNLNVVPPHVEFLRPL---TDLQVREKEMARFECELSRE 5903
Query: 553 PPPKAMWSRGDKAIMEG 569
K W + I +G
Sbjct: 5904 -NAKVKWFKDGAEIKKG 5919
Score = 120 bits (301), Expect = 7e-27
Identities = 124/479 (25%), Positives = 201/479 (41%), Gaps = 76/479 (15%)
Query: 463 KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY--VFAPDAYNVTLPAKVHVID 520
KWTK G + S R + +LVI A D G Y V + KV VI
Sbjct: 23672 KWTKEGQDI--SKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIG 23729
Query: 521 PPKIILDGLDADNTVTVIAGNKLRLEIPISGEPP------------------PKAMWSRG 562
P L+ D+ + +S PP PKA W
Sbjct: 23730 SPNSPEGPLEYDDIQV--------RSVRVSWRPPADDGGADILGYILERREVPKAAWYTI 23781
Query: 563 DKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG-----EAHASIKVKV- 616
D R+R ++LV+ + + + ++ +N+ G ++ + K
Sbjct: 23782 DS-------RVR------GTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTP 23828
Query: 617 VDFPDPPV-APTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCK 675
++ P+PP P V +V ++W P DGGS + GY+IERK+ + +W+R N
Sbjct: 23829 LNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQIT 23888
Query: 676 ETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDT 732
T + ++ Y+ RI A N +G+S+ S S P V P S P L + S++
Sbjct: 23889 TTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKD 23948
Query: 733 TVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDK 792
+VT++W P+ G + GY +EY ++G++A W +NK+ I
Sbjct: 23949 SVTLQWEKPECDGGKEILGYWVEY-----------RQSGDSA-------WKKSNKERIKD 23990
Query: 793 TKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEII-EPPKIRIPRHLKQTYIR 851
+FTI GL + RV A N G S P+ + I K E P IR + +K
Sbjct: 23991 KQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIR--KEMKDV-TT 24047
Query: 852 RVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDT-IIFIRKAERSHSGKY 909
++GEA L G+P P++ W + G E+ +++ +S+ T + + E+ G Y
Sbjct: 24048 KLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVY 24106
Score = 118 bits (295), Expect = 4e-26
Identities = 143/575 (24%), Positives = 215/575 (37%), Gaps = 93/575 (16%)
Query: 597 YHINLKNEAGEAHASIKVKVVDF------PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSP 650
+ ++ +NE G S K V P PPV P + + + W+PP +DGGS
Sbjct: 10587 FRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSK 10646
Query: 651 ILGYFIERKKKQSSRWMRLNF--DLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMP 708
ILGY +E +K W R N + C ET ++ + +G Y+ R+ AVNA G S P+
Sbjct: 10647 ILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHV 10706
Query: 709 SRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSD 768
P + PP L + D + HI D L +G
Sbjct: 10707 PEPVLVKDRLEPPEL-----ILDANMARE----QHIKVG--DTLRLSAIIKG-------- 10747
Query: 769 ENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAG----ASEPKYY 824
P W ++D K + +T P +K+ +R A G E
Sbjct: 10748 ------VPFPKVTWKKEDRDAPTKARIDVT--PVGSKLEIRNAAHEDGGIYSLTVENPAG 10799
Query: 825 SQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKK---DGAEID 881
S+ + VK ++ K PR L+ + IR K LTWK+ DG +
Sbjct: 10800 SKTVSVKVLVLD-KPGPPRDLEVSEIR--------------KDSCYLTWKEPLDDGGSVI 10844
Query: 882 KNQINIRNSETD---TIIFIRKAERSHSGKY-------------DLQVKVDKFVETASID 925
N + R + + ++SH K+ + Q FVET
Sbjct: 10845 TNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPK-P 10903
Query: 926 IQIIDR---PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVI 982
I+ +D PGPP+ + DV V+L W P DG + ITGY ++ ++ + +W
Sbjct: 10904 IKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIK-F 10962
Query: 983 EHYHRTSATITELVIGNEYYFRVFSENMCGLS-EDATMTKESAVIARDGKIYKNPVYEDF 1041
+ +T L G Y FRV +EN+ GL D T+ E K+ V D
Sbjct: 10963 KTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLPDTTIPIEC-----QEKLVPPSVELDV 11017
Query: 1042 DFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGV 1101
E + AG +RG P P W + I D Y + ++
Sbjct: 11018 KLIEGLVVK---------AGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFS 11068
Query: 1102 CTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
L I+ D G Y N G+ + L V
Sbjct: 11069 SVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 11103
Score = 116 bits (290), Expect = 1e-25
Identities = 185/884 (20%), Positives = 323/884 (36%), Gaps = 156/884 (17%)
Query: 313 NCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDT-TAYCGERVELECEV-SEDDA 370
N DS +TA DE + P + + +D + GE LE ++ +
Sbjct: 18188 NFSEPSDSSGAITARDE-------IDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIP 18240
Query: 371 NVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEY--SVMTTGGQSSAKLSV 428
+V W K+G+E+ +R I+ +K L+++ + D +Y + GG S ++V
Sbjct: 18241 DVVWSKDGKEL-EETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITV 18299
Query: 429 DLK--------PLKIL------------TPLTDQTVNLGKEICLKCEISENIPGKWTKNG 468
+ PLK+ PL D N+ I K E S WT+
Sbjct: 18300 KVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRL---SWTQVS 18356
Query: 469 LPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF---APDAYNVTLPAKVHVID----- 520
VQ + ++ KL+ N +Y+F A + Y + P + +
Sbjct: 18357 TEVQALNY-------KVTKLLPGN-------EYIFRVMAVNKYGIGEPLESGPVTACNPY 18402
Query: 521 -----PPKIILDGLDADNTVTVIA------GNKLRLEIPISGEPPPKAMWSRGDKAIMEG 569
P + + D+ V A G ++ I + W++ +K +
Sbjct: 18403 KPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYI-LEKRDKEGVRWTKCNKKTLTD 18461
Query: 570 SGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGE-AHASIKVKVVDF---PDPPVA 625
R+R + + +A + +GV GE + S+ + D P PP
Sbjct: 18462 L-RLRVTGLTEGHSYEFRVAAENAAGV---------GEPSEPSVFYRACDALYPPGPPSN 18511
Query: 626 PTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETT------F 679
P VT+ + W P YDGG+P+ GY +E K+ + W C T F
Sbjct: 18512 PKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTT-----CTPPTGLQGKQF 18566
Query: 680 EPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTL-----------LTVDS 728
K+ E Y RI A+N+ G+ +P+ V PP + L +
Sbjct: 18567 TVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASA 18626
Query: 729 VTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKD 788
VT++ RP + +G + + TS+ ++ N
Sbjct: 18627 TLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTM--------------LVIDNVT 18672
Query: 789 LIDKTKFTIT--GLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLK 846
D ++ +T FV V+ +++ A P+ + I E K + +
Sbjct: 18673 RFDSGRYNLTLENNSGSKTAFVNVRVLDSPSA--------PVNLT-IREVKKDSVTLSWE 18723
Query: 847 QTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHS 906
I + N ++ + R + K I N + + R S
Sbjct: 18724 PPLIDGGAKITNYIVEKRETTRKAYATITNNCT--KTTFRIENLQEGCSYYFRVLA---S 18778
Query: 907 GKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGY 966
+Y + + + + +++ + P PP V + DV + W P+ DG + ITGY
Sbjct: 18779 NEYGIGLPAE-----TTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGY 18833
Query: 967 TIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVI 1026
++ K S +W T + ATI+ L G EY FRV + N G S+ + VI
Sbjct: 18834 VVEMQTKGSEKWSTCTQ-VKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVP--VI 18890
Query: 1027 ARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVA 1086
ARD +I P P A ++ +G P+ + W K+
Sbjct: 18891 ARDIEI-------------KPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQT 18937
Query: 1087 IVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEI 1130
+ + R + S++ V +L I++ S D GTY N G++ +
Sbjct: 18938 LKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITV 18981
Score = 115 bits (288), Expect = 2e-25
Identities = 180/802 (22%), Positives = 307/802 (38%), Gaps = 107/802 (13%)
Query: 373 KWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKP 432
KW +G EI Y + + +L I+ + D EY + + S ++V L
Sbjct: 11046 KWTTDGSEI--KTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 11103
Query: 433 LKILTPLTDQTVNLG---KEICLKCEISENIPGKWTKNGLPVQESDRLK----VVHKGRI 485
L + P T L + + + + ++ G N + V++ D K VV G
Sbjct: 11104 LDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYI-VEKQDTRKDTWGVVSSGSS 11162
Query: 486 H-KLVIANALTEDEGDYVFAPDAYNV---------TLPAKVHVIDPPKIILDGLDADNTV 535
KL I + + +YVF A N T H PP V
Sbjct: 11163 KTKLKIPHL--QKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSP-----PGKPVV 11215
Query: 536 TVIAGNKLRLE--IPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERD- 592
T I N + +P S P + + + R+ D V + E +
Sbjct: 11216 TDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVNKTPIADLKFRVTGLYEGNT 11275
Query: 593 -DSGVYHINLKNEAGEAHASIKVKV---VDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGG 648
+ V+ NL + + +S +K + P PP+ P + + + + W P DGG
Sbjct: 11276 YEFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGG 11335
Query: 649 SPILGYFIERKKKQSSRWMRLNFD-LCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSM 707
SPILGY +E +K +++W R+N D L ++ F +IEG Y RI A N +G +P
Sbjct: 11336 SPILGYVVECQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRE 11395
Query: 708 PSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAA--GLDGYVLEYCFEGSTSAK 765
+ + + PP + +D +T+R I A G + + EG +
Sbjct: 11396 LAESVIAKDILHPPEV-ELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVR 11454
Query: 766 QSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYS 825
+ + + DLP + + D K+ I+ A N++G ++
Sbjct: 11455 E--KRVDLIQDLPRVELQIKEAVRADHGKYIIS-------------AKNSSG------HA 11493
Query: 826 QPILVKEIIEPPKIRIPRHLKQTYIRRVG--------------EAVNLVIPFQGKPRPEL 871
Q + +++ P ++LK T + + E N ++ ++ KP +
Sbjct: 11494 QGSAIVNVLDRPGPC--QNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYR-KPNQK- 11549
Query: 872 TWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETAS--IDIQII 929
W +++ K I + F AE +V V +ET + + I I
Sbjct: 11550 GWSIVASDVTKRLIKANLLANNEYYFRVCAEN--------KVGVGPTIETKTPILAINPI 11601
Query: 930 DRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTS 989
DRPG P+ + I D V L W P DG + Y +++ K S +W V + + +
Sbjct: 11602 DRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKET 11661
Query: 990 ATITELVIGNEYY-FRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPM 1048
+ + + N+ Y FRV ++N G S+ + E V+ D + P+
Sbjct: 11662 HYMVDRCVENQIYEFRVQTKNEGGESD--WVKTEEVVVKED--------------LQKPV 11705
Query: 1049 FTQPLVNTYAI-AGYNATLNCSVRGNPKPKITWMKNKVA--IVDDPRYRMFSNQGVCTLE 1105
L + AG L VRG P P++ W K+K A + PR ++ +
Sbjct: 11706 LDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFS 11765
Query: 1106 IRKPSPYDGGTYCCKAVNDLGT 1127
+ K DGG Y A N G+
Sbjct: 11766 LTKAKRSDGGKYVVTATNTAGS 11787
Score = 115 bits (288), Expect = 2e-25
Identities = 190/873 (21%), Positives = 328/873 (37%), Gaps = 153/873 (17%)
Query: 324 VTAGDEKCSTELFVREPPIMVTKQLEDT-TAYCGERVELECEV-SEDDANVKWFKNGEEI 381
+TA DE V P I + + +DT + GE +++ ++ + ++W K +E+
Sbjct: 16035 ITARDE-------VDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQEL 16087
Query: 382 IPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTD 441
+R I+ L ++ A + D+ Y + ++V++K L P
Sbjct: 16088 --SNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEG 16145
Query: 442 QTVNLGKEICLKCEISENIPGKWTKNGLPVQE--SDRLKVVHKGR-----IHKLVIANAL 494
V G KC ++ W P+Q+ SD + + + R + +V AN
Sbjct: 16146 PVVISGVT-AEKCTLA------WKP---PLQDGGSDIINYIVERRETSRLVWTVVDANVQ 16195
Query: 495 TED-------EG-DYVF---APDAYNVTLPAKVH--VIDPPKIILDGLDADNTVTVIAGN 541
T EG +Y F A + Y V P + V P ++ D A TV +
Sbjct: 16196 TLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDS 16255
Query: 542 KLRL-EIPISG------------EPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDI 588
+ + E P S W+R K ++ G R+R V +
Sbjct: 16256 MIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLI-GELRLR----------VTGL 16304
Query: 589 AERDDSGVYHINLKNEAGEAHAS---IKVKVVD---FPDPPVAPTVTEVGDDWCIMNWEP 642
E D + ++ +N AG + S K D P PP P V ++ ++W
Sbjct: 16305 IENHDYE-FRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSK 16363
Query: 643 PAYDGGSPILGYFIERKKKQSSRWMRLNFDL-CKETTFEPKKMIEGVAYEVRIFAVNAIG 701
P YDGG I GY +E+ W +T E +K++E Y RI A+N G
Sbjct: 16364 PIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAG 16423
Query: 702 ISKPSMPSRPFVPLAVTSPPTL-----------LTVDSVTDTTVTMRWRPPDHIGAAGLD 750
+ + + P + P + + V ++ RP + +D
Sbjct: 16424 VGEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVD 16483
Query: 751 GYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTIT--GLPTDAKIFV 808
G + + TS+ S ++ N + D K+T+T FV
Sbjct: 16484 GEIRDAAIIDVTSSFTS--------------LVLDNVNRYDSGKYTLTLENSSGTKSAFV 16529
Query: 809 RVKAVNAAGASEPKYYSQPILVKEII----EPPKIRIPRHLKQTYIRRVGEAVNLVIPFQ 864
V+ ++ S P + K+ + EPP + +K + +
Sbjct: 16530 TVRVLDTP--SPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEK------------ 16575
Query: 865 GKPRPELTWKKDGAEID---KNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVET 921
E T K A + KN I + + R + G + +T
Sbjct: 16576 ----REATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYG-------IGLPAQT 16624
Query: 922 ASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV 981
A I++ + P PP + ++DV +V+L+WT P+ DG + I Y ++ K S +W +
Sbjct: 16625 AD-PIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKW-SE 16682
Query: 982 IEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDF 1041
A IT L G EY FRV + N G S+ ++ ++A+D I +
Sbjct: 16683 CARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVP--IVAKDLVIEPD------ 16734
Query: 1042 DFSEAPMFTQPLVNTYAI-AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQG 1100
+P ++Y++ G + + + G PKP ITW K+ + + R + +
Sbjct: 16735 --------VKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLD 16786
Query: 1101 VCTLEIRKPSPYDGGTYCCKAVNDLG--TVEIE 1131
+ TL I++ DGG Y N +G T IE
Sbjct: 16787 LTTLSIKETHKDDGGQYGITVANVVGQKTASIE 16819
Score = 115 bits (287), Expect = 3e-25
Identities = 101/370 (27%), Positives = 158/370 (42%), Gaps = 34/370 (9%)
Query: 266 KGGRVRFVVELAD-----------------PKLEVKWYKNGQEIRPSTKYIFEHKGCQRI 308
+G V FV EL D +E KWY N E++ + KY + ++
Sbjct: 2217 EGAVVEFVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQN 2276
Query: 309 LFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSED 368
L + + D EY +K + +L ++ PI + + L D G+ V+LE +VS +
Sbjct: 2277 LTVKDVTKEDQGEYSFVIDGKKTTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLE 2336
Query: 369 DANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSV 428
W K+G+E+ P R I ++ + H+L+IE TK DA YS S V
Sbjct: 2337 SVEGVWMKDGQEV--QPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRV 2394
Query: 429 DLKPLKILTPLTDQTVNLGKEICLKCEIS--ENIPGKWTKNGLPVQESDRLKVVHKGRIH 486
+ + ++TPL D V G + L+C++S + KW N ++ DR++ + KG
Sbjct: 2395 SVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQ 2454
Query: 487 KLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLE 546
+LVI DEG Y V I I+ GL D T T +E
Sbjct: 2455 RLVINRTHASDEGPYKLIVGRVETNCNLSVEKIK----IIRGL-RDLTCTETQNVVFEVE 2509
Query: 547 IPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG 606
+ SG +W+ DK I + S + + E++ L + +DD G Y AG
Sbjct: 2510 LSHSG---IDVLWNFKDKEI-KPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTF----YAG 2561
Query: 607 EAHASIKVKV 616
E S K+ V
Sbjct: 2562 ENMTSGKLTV 2571
Score = 110 bits (276), Expect = 6e-24
Identities = 178/830 (21%), Positives = 319/830 (38%), Gaps = 108/830 (13%)
Query: 352 TAYCGERVELECEVS-EDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADA 410
T G + L+ V + + + W K +E+ K ++ GK+ +I+ ++D+
Sbjct: 22561 TIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEK--VSLQYTGKRATAVIKFCDRSDS 22618
Query: 411 AEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIP-----GKWT 465
+Y++ + +SV +K L P TV+ + KC ++ ++P + T
Sbjct: 22619 GKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTVSRVTQE--KCTLAWSLPQEDGGAEIT 22676
Query: 466 KNGLPVQESDRLK-VVHKGRIHKLVIANALTEDEGDYVF---APDAYNVTLPAKVH---- 517
+ +E+ RL V+ +G L +Y+F A + Y +P +
Sbjct: 22677 HYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVA 22736
Query: 518 ----VIDPPKIILDGLDADNTVTVI--------AGNKLRLEIPISGEPPPKAMWSRGDKA 565
I P I + + +I GN++ + + W+R +K
Sbjct: 22737 RNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYL-VDKREKKSLRWTRVNKD 22795
Query: 566 IMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDF-PDPPV 624
+ R++ S + + + +G +E EA I + + P PP
Sbjct: 22796 YVVYDTRLKVTSLMEGCDYQFRVTAVNAAG------NSEPSEASNFISCREPSYTPGPPS 22849
Query: 625 APTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLC-KETTFEPKK 683
AP V + + W P YDGG+ I+GY +E ++K + +W R++ + + T F
Sbjct: 22850 APRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPD 22909
Query: 684 MIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDH 743
+ G Y R+ AVN G+S+ S P+ P L D + T VT+R
Sbjct: 22910 LKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKT-VTIRAGASLR 22968
Query: 744 --IGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLP 801
+ +G V+ + +G A ++ + +Y L IV + D K+TI
Sbjct: 22969 LMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSL----LIVDKVNRYDAGKYTI---- 23020
Query: 802 TDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEP---PKIRIPRHLKQTY-----IRRV 853
+A N +G S +LVK P P +++ + + I +
Sbjct: 23021 ---------EAENQSGKK-----SATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTI 23066
Query: 854 --GEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDL 911
G VN I + + +K + K I T+ + R + G
Sbjct: 23067 DGGAPVNNYI-VEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYG---- 23121
Query: 912 QVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKA 971
+ + ET+ + + + P P +++ DV V L W P DG + +TGY ++
Sbjct: 23122 ---IGEPCETSDA-VLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEAC 23177
Query: 972 DKKSMEWF-------TVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESA 1024
+ W TV+EH T+T L G +Y FR+ ++N G+SE +A
Sbjct: 23178 KAGTERWMKVVTLKPTVLEH------TVTSLNEGEQYLFRIRAQNEKGVSEPRETV--TA 23229
Query: 1025 VIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNK 1084
V +D ++ D S T P + AG L + G P P +W
Sbjct: 23230 VTVQDLRVLPT-----IDLS-----TMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAG 23279
Query: 1085 VAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKL 1134
+ + R + ++ V L IR+ + D G Y + N GT K+
Sbjct: 23280 SKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKV 23329
Score = 109 bits (272), Expect = 2e-23
Identities = 92/363 (25%), Positives = 161/363 (44%), Gaps = 18/363 (4%)
Query: 269 RVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGD 328
R F E+++P + V+W K+ QE++ + + + + L I + +M+D +Y V AG
Sbjct: 3028 RAMFECEVSEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGG 3087
Query: 329 EKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSR 388
+ +LFV + + ++ +R +E EV+EDD + W+K+G EI + R
Sbjct: 3088 NVSTAKLFVEGRDVRIRSIKKEVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQER 3147
Query: 389 YRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDL-KPLKILTPLTDQTVNLG 447
++ VE + H + I ++DA EY+ + +SS L V+ +P ++L L TV G
Sbjct: 3148 HKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSG 3207
Query: 448 KEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF-A 504
K IS K W K + + K +H G+ + L++ A ED Y A
Sbjct: 3208 KPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEA 3267
Query: 505 PDAYNVTLPAKVHVIDPPKIILDGLD-----------ADNTVTVIAGNKLRLEIPISGEP 553
+ Y V + ++ P+++ + +TVT G R + +SG
Sbjct: 3268 KNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVT-SEGQPARFQCRVSG-T 3325
Query: 554 PPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIK 613
K W DK I + S R + D+ L I A +D G Y N G+ ++
Sbjct: 3326 DLKVSWYSKDKKI-KPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTAN 3384
Query: 614 VKV 616
+ +
Sbjct: 3385 LSL 3387
Score = 108 bits (270), Expect = 3e-23
Identities = 103/437 (23%), Positives = 169/437 (38%), Gaps = 53/437 (12%)
Query: 719 SPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLP 778
SP L D + +V + WRPP G A + GY+LE ++P
Sbjct: 23733 SPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILE------------------RREVP 23774
Query: 779 AEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPK 838
W + + T + GL + + RV A N G S+P +P+ K + PP+
Sbjct: 23775 KAAWYTIDSR-VRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPE 23833
Query: 839 IRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQIN----IRNSETD- 893
P + +V+L +P+ + + G I++ + + +R+++T
Sbjct: 23834 ---PPSNPPEVLDVTKSSVSLS---WSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQI 23887
Query: 894 TIIFIRKAERSHSGKYDLQVKVDKFV---ETASIDIQII-----DRPGPPQIVKIEDVWG 945
T +Y ++ V ET+ ++ D+P P ++I +
Sbjct: 23888 TTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISK 23947
Query: 946 ENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF-TVIEHYHRTSATITELVIGNEYYFR 1004
++V L W P+ DG I GY ++ W + E TI L+ EY FR
Sbjct: 23948 DSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFR 24007
Query: 1005 VFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNA 1064
VF+EN GLS G EAP + + + G A
Sbjct: 24008 VFAENETGLSRPRRTAMSIKTKLTSG--------------EAPGIRKEMKDVTTKLGEAA 24053
Query: 1065 TLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVND 1124
L+C + G P P I W + ++ +Y+M S+ TL + D G Y C A N+
Sbjct: 24054 QLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNE 24113
Query: 1125 LGTVEIECKLEVKVIAQ 1141
+G VE KL ++ Q
Sbjct: 24114 VGEVETSSKLLLQATPQ 24130
Score = 107 bits (268), Expect = 5e-23
Identities = 123/468 (26%), Positives = 198/468 (42%), Gaps = 56/468 (11%)
Query: 196 RREVKQQEEE---PQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSA 252
R + K++ EE + EL K YE++ + +L K + EEKK+
Sbjct: 1952 RSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRK----TKDELLHWTKELTEEEKKAL 2007
Query: 253 AF-AKILDPAYQVDK-----------------------GGRVRFVVELAD-PKLEVKWYK 287
A KI P ++ DK G F V + P E +WYK
Sbjct: 2008 AEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYK 2067
Query: 288 NGQEIRPSTK---YIFEHKGCQRILFINNCQMTDDSEYYV----TAGDEKCSTELFVREP 340
NG +I S + Y E C+ L I + D + V AG+ L V+
Sbjct: 2068 NGVKIERSDRIYWYWPEDNVCE--LVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAK 2125
Query: 341 PIMV-TKQLEDTTAYCGERV-ELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKH 398
++ T++L+D A + + ECE SE VKW+K+G E+ G K YR+ + K H
Sbjct: 2126 QLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGDK--YRMHSDRKVH 2183
Query: 399 ILIIEGATKADAAEYS---VMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCE 455
L I +DA +YS V +++AKL V+ ++ + L D V L+C
Sbjct: 2184 FLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGELECI 2243
Query: 456 IS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPA 514
+S ENI GKW N + ++ + + + + L + + ED+G+Y F D T
Sbjct: 2244 VSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTT--C 2301
Query: 515 KVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIR 574
K+ + P IL GL V G+ ++LE+ +S E + +W + D ++ S R+
Sbjct: 2302 KLKMKPRPIAILQGLSDQK---VCEGDIVQLEVKVSLE-SVEGVWMK-DGQEVQPSDRVH 2356
Query: 575 TESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDP 622
S L+I+ ++D+G Y + + V VD P
Sbjct: 2357 IVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDVITP 2404
Score = 107 bits (266), Expect = 8e-23
Identities = 171/808 (21%), Positives = 305/808 (37%), Gaps = 106/808 (13%)
Query: 356 GERVELECEVSEDDA-NVKWFKNGEEIIPGPKSRYRIRVEGKKHI--LIIEGATKADAAE 412
G V+L +S A ++W+K+ +E+ ++ + VE + ++I+ A + ++
Sbjct: 20390 GTSVKLRAGISGKPAPTIEWYKDDKEL----QTNALVCVENTTDLASILIKDADRLNSGC 20445
Query: 413 YSVMTTGGQSSAKLSVDL----KPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNG 468
Y + SA ++ + KP P+ +TV K L +++ K T
Sbjct: 20446 YELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYI 20505
Query: 469 LPVQESDRLK-VVHKGRIHKLVIANALTEDEGDYVF---APDAYNVTLPAKVH-VIDPPK 523
+ +E+ R+ + + + +I +Y+F A + Y + P + V+
Sbjct: 20506 VEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNA 20565
Query: 524 IILDGLDADNTVTVIAGNKLRL----EIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYP 579
+ G VT I N + + I G + DK + G ++ E+
Sbjct: 20566 FVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSL-GWFKVLKETIR 20624
Query: 580 DSSTLVIDIAERDDSGVYHINLKNEAGE---AHASIKVKVVDFPDPPVAPTVTEVGDDW- 635
D+ V + E D Y + N AG+ + S K D DPP P + D
Sbjct: 20625 DTRQKVTGLTENSDYQ-YRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTK 20683
Query: 636 --CIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNF-DLCKETTFEPKKMIEGVAYEV 692
+ W P YDGGS + GY +E ++ + W ++ + T + + GV Y
Sbjct: 20684 SSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYF 20743
Query: 693 RIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGY 752
R+ AVN G +P + P + P + D V +R I AG D
Sbjct: 20744 RVSAVNCAGQGEPIEMNEPVQAKDILEAPEI-------DLDVALR---TSVIAKAGEDVQ 20793
Query: 753 VLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKA 812
VL F+G P W K+L +++I TD+ + +
Sbjct: 20794 VL-IPFKGRPP--------------PTVTWRKDEKNLGSDARYSIEN--TDSSSLLTIPQ 20836
Query: 813 VN-----------AAGASEPKYYSQPILVKEIIEP---PKIRIPRHLKQTYIRRVGE--- 855
V G EPK S + VK + P K+++ +H+ + + + +
Sbjct: 20837 VTRNDTGKYILTIENGVGEPK--SSTVSVKVLDTPAACQKLQV-KHVSRGTVTLLWDPPL 20893
Query: 856 ------AVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKY 909
+N VI + + + TW + + + T F R + G
Sbjct: 20894 IDGGSPIINYVI--EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIG-- 20949
Query: 910 DLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQ 969
+ + ET ++ + P P + + ++D +V L+WT P DG + IT Y ++
Sbjct: 20950 -----IGEPCETTE-PVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVE 21003
Query: 970 KADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARD 1029
+ K W + +++L + FRVF++N GLS+ T+
Sbjct: 21004 RKGKGEQTW-SHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTI---------- 21052
Query: 1030 GKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVD 1089
G I V E E + P G+N L +G PKP I+W+K+ + + +
Sbjct: 21053 GPI---TVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKE 21109
Query: 1090 DPRYRMFSNQGVCTLEIRKPSPYDGGTY 1117
R + TL I+ GG Y
Sbjct: 21110 SEFVRFSKTENKITLSIKNAKKEHGGKY 21137
Score = 106 bits (265), Expect = 1e-22
Identities = 117/456 (25%), Positives = 185/456 (40%), Gaps = 83/456 (18%)
Query: 597 YHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFI 656
Y +N + + AS + + D P P VT+V + W PAYDGGS ++GY I
Sbjct: 22419 YALNAAGVSKASEASRPIMAQNPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYII 22478
Query: 657 ERK---KKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIG-ISKPSMPSRPF 712
ERK + RW++ N+ + + F + EG YE R+ A NA G ISK S + P
Sbjct: 22479 ERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPV 22538
Query: 713 VPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGE 772
+PP + VT+R AG D VL+ G K G+
Sbjct: 22539 TCRDEYAPPKAELDARLHGDLVTIR---------AGSD-LVLDAAVGGKPEPKIIWTKGD 22588
Query: 773 AAYDL----------PAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPK 822
DL ++ D D K+T+T NA+G
Sbjct: 22589 KELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLT-------------VKNASGTK--- 22632
Query: 823 YYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTW----KKDGA 878
+ ++VK + P G L + + + L W + GA
Sbjct: 22633 --AVSVMVKVLDSP-----------------GPCGKLTVSRVTQEKCTLAWSLPQEDGGA 22673
Query: 879 EI--------DKNQIN--IRNSETDTIIFIRKAERSHSGKYDLQVK-VDKFVETASIDIQ 927
EI + +++N I E T+ ++ + +Y +V+ V+K+ ++ +
Sbjct: 22674 EITHYIVERRETSRLNWVIVEGECPTLSYV-VTRLIKNNEYIFRVRAVNKYGPGVPVESE 22732
Query: 928 -IIDR-----PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV 981
I+ R P PP I + E++ + WT P+ DG I+ Y + K +KKS+ W V
Sbjct: 22733 PIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRV 22792
Query: 982 IEHY--HRTSATITELVIGNEYYFRVFSENMCGLSE 1015
+ Y + T +T L+ G +Y FRV + N G SE
Sbjct: 22793 NKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSE 22828
Score = 106 bits (264), Expect = 1e-22
Identities = 128/545 (23%), Positives = 211/545 (38%), Gaps = 64/545 (11%)
Query: 620 PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTF 679
P PP P V + + W+PPA DGGSPI GY +E +++ ++ W R+N TT
Sbjct: 9208 PGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTC 9267
Query: 680 E--PKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMR 737
E + E Y R+ AVN G S+PS + + P + +D + +
Sbjct: 9268 ECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVF-IDIGAQDCLVCK 9326
Query: 738 WRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTI 797
I A + +E AK++ ++G +D+P + A + + + I
Sbjct: 9327 AGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDG--VHDIPED----AQLETAENSSVII 9380
Query: 798 TGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAV 857
+P + ++ A + K + + V ++ PPK LK + I R +
Sbjct: 9381 --IPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPK-----DLKVSDITRGSCRL 9433
Query: 858 NLVIP------------FQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIR-KAERS 904
+ +P + + W K + + + ++ F R +AE
Sbjct: 9434 SWKMPDDDGGDRIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAEN- 9492
Query: 905 HSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAIT 964
++ + V+ T + D I P PP +KI + V L+W PPK+DG + +T
Sbjct: 9493 ---RFGIGPPVETIQRTTARDP--IYPPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVT 9547
Query: 965 GYTIQ-----KADKKSMEWFTVIEH-YHRTSATITELVIGNEYYFRVFSENMCGLSEDAT 1018
Y ++ K W + T+ +LV G EY FRV + N G+S+ +
Sbjct: 9548 HYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPSA 9607
Query: 1019 MTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKI 1078
D P + +F E G N + ++G P P +
Sbjct: 9608 TVGPCDCQRPD----MPPSIDLKEFMEVE------------EGTNVNIVAKIKGVPFPTL 9651
Query: 1079 TWMK-------NKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIE 1131
TW K NK ++ D CTL I + D G Y AVN+LGT E
Sbjct: 9652 TWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKE 9711
Query: 1132 CKLEV 1136
+L V
Sbjct: 9712 MRLNV 9716
Score = 105 bits (263), Expect = 2e-22
Identities = 101/375 (26%), Positives = 158/375 (42%), Gaps = 21/375 (5%)
Query: 263 QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 322
+V +G V+ V+++ +E W K+GQE++PS + +L I + D Y
Sbjct: 2320 KVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNY 2379
Query: 323 YVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDD-ANVKWFKNGEEI 381
T ST V + V L+D G + LEC+VS D +VKW+ N E+I
Sbjct: 2380 SFTIPALGLSTSGRVSVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQI 2439
Query: 382 IPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTD 441
P R + V+G K L+I +D Y ++ +++ LSV+ +KI+ L D
Sbjct: 2440 --KPDDRVQAIVKGTKQRLVINRTHASDEGPYKLIVGRVETNCNLSVE--KIKIIRGLRD 2495
Query: 442 QTVNLGKEICLKCEISEN-IPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGD 500
T + + + E+S + I W ++ S + K+ G+I+KL + N + +DEG
Sbjct: 2496 LTCTETQNVVFEVELSHSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGK 2555
Query: 501 YVF--APDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAM 558
Y F + + L I P D TV E+ P K
Sbjct: 2556 YTFYAGENMTSGKLTVAGGAISKPL-------TDQTVAESQEAVFECEV---ANPDSKGE 2605
Query: 559 WSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVD 618
W R K + + IR+ES L+I + DD G Y K + A +KV+ V
Sbjct: 2606 WLRDGKH-LPLTNNIRSESDGHKRRLIIAATKLDDIGEY--TYKVATSKTSAKLKVEAVK 2662
Query: 619 FPDPPVAPTVTEVGD 633
TVTE D
Sbjct: 2663 IKKTLKNLTVTETQD 2677
Score = 103 bits (258), Expect = 7e-22
Identities = 110/456 (24%), Positives = 174/456 (38%), Gaps = 80/456 (17%)
Query: 702 ISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGS 761
+ KP +P+ P + D VT +T++W PP G + + Y+LE
Sbjct: 13576 VGKPGIPTGP------------IKFDEVTAEAMTLKWAPPKDDGGSEITNYILE------ 13617
Query: 762 TSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGA--- 818
K+ N + W+ + KT F +T L + RV A N G
Sbjct: 13618 ---KRDSVNNK---------WVTC-ASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEG 13664
Query: 819 --SEPKYYSQPILVKEIIEPPKIRIPRH----LKQTYIRRVGEAVNLVIPFQGKPRPELT 872
SEP P V + PP I RH L T ++ G + + K R L
Sbjct: 13665 LKSEPIVARHPFDVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLL 13724
Query: 873 WKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETAS--------I 924
WK+ +K I +R+ + + + +Y+ +V +
Sbjct: 13725 WKR----ANKTPIRMRDFKVTGL--------TEGLEYEFRVMAINLAGVGKPSLPSEPVV 13772
Query: 925 DIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIE- 983
+ ID PG P+++ I +V L WT PK DG +TGY ++K D S W
Sbjct: 13773 ALDPIDPPGKPEVINITR---NSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHV 13829
Query: 984 HYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDF 1043
+ + T+T+LV G +Y FR+ ++N G + + E+ +I +D ++
Sbjct: 13830 NVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTET-IICKD------------EY 13876
Query: 1044 SEAPMFTQPLVNTYAI--AGYNATLNC-SVRGNPKPKITWMKNKVAIVDDPRYRMFSNQG 1100
+ P + AG LN S+ G P PK +W K I ++ S
Sbjct: 13877 EAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPT 13936
Query: 1101 VCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
L I+ + D G Y A N GT K+ V
Sbjct: 13937 SSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTV 13972
Score = 102 bits (255), Expect = 2e-21
Identities = 103/389 (26%), Positives = 171/389 (43%), Gaps = 15/389 (3%)
Query: 248 EKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHK-GCQ 306
E+ F K L+ V KG + EL + + +V W K+G+ + I G
Sbjct: 4711 EELPVRFVKTLEEEVTVVKGQPLYLSCEL-NKERDVVWRKDGKIVVEKPGRIVPGVIGLM 4769
Query: 307 RILFINNCQMTDDSEYYVT---AGDEKCSTELFVREP-PIMVTKQLEDTTAYCGERVELE 362
R L IN+ TD Y VT A + +CS+ + V E + K + D
Sbjct: 4770 RALTINDADDTDAGTYTVTVENANNLECSSCVKVVEVIRDWLVKPIRDQHVKPKGTAIFA 4829
Query: 363 CEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQS 422
C++++D N+KWFK +EI P + I +G L I+ A D AEY+V G +
Sbjct: 4830 CDIAKDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGKRY 4889
Query: 423 SAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVH 481
AKL++ + +++L P+ D T+ + EISE +IPG+W G ++ S ++
Sbjct: 4890 PAKLTLGEREVELLKPIEDVTIYEKESASFDAEISEADIPGQWKLKGELLRPSPTCEIKA 4949
Query: 482 KGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGN 541
+G L + + G+ ++ A N A ++ +I LD VTV
Sbjct: 4950 EGGKRFLTLHKVKLDQAGEVLY--QALNAITTA---ILTVKEIELDFAVPLKDVTVPERR 5004
Query: 542 KLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINL 601
+ R E ++ E +WS+G I++ S + + LVI+ ++ DD GVY +
Sbjct: 5005 QARFECVLTRE--ANVIWSKGPD-IIKSSDKFDIIADGKKHILVINDSQFDDEGVYTAEV 5061
Query: 602 KNEAGEAHASIKVKVVDFPDPPVAPTVTE 630
+ + A + + F P TV E
Sbjct: 5062 EGKKTSARLFVTGIRLKFMSPLEDQTVKE 5090
Score = 102 bits (254), Expect = 2e-21
Identities = 85/281 (30%), Positives = 121/281 (43%), Gaps = 16/281 (5%)
Query: 283 VKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPI 342
V W K I+ S K+ G + IL IN+ Q D+ Y +K S LFV +
Sbjct: 5018 VIWSKGPDIIKSSDKFDIIADGKKHILVINDSQFDDEGVYTAEVEGKKTSARLFVTGIRL 5077
Query: 343 MVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILII 402
LED T GE CE+S + +V WFKN ++ I EGK H L +
Sbjct: 5078 KFMSPLEDQTVKEGETATFVCELSHEKMHVVWFKNDAKL--HTSRTVLISSEGKTHKLEM 5135
Query: 403 EGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPG 462
+ T D ++ S+A+L V L D+T EI LKCE+S+++P
Sbjct: 5136 KEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSKDVPV 5195
Query: 463 KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV----FAPDAYNVTLPAKVHV 518
KW K+G + S + + G L I A +D+G+YV NVT+ A++
Sbjct: 5196 KWFKDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIK 5255
Query: 519 IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMW 559
++ P L G V V G EI +S EP W
Sbjct: 5256 VEKP---LYG------VEVFVGETAHFEIELS-EPDVHGQW 5286
Score = 102 bits (254), Expect = 2e-21
Identities = 179/762 (23%), Positives = 289/762 (37%), Gaps = 135/762 (17%)
Query: 340 PPIMVTKQLEDTTAYCGERVELECEV-SEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKH 398
P I++ +Q+ T G+++ +E V + KW K +E++ S +
Sbjct: 12403 PKILMPEQI---TIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTS--SHLAVHKADSSS 12457
Query: 399 ILIIEGATKADAAEYSVMT--TGGQSSAKLSV--------------------DLKPLKIL 436
ILII+ T+ D+ YS+ + G + K+ V D L
Sbjct: 12458 ILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWH 12517
Query: 437 TPLTDQTVNLGKEICLKCEISENIPGKW-TKNGLPVQESDRLKVVHKGRIH--------K 487
PL D N+ I KC++S G W T + S R+ + G+ + +
Sbjct: 12518 IPLEDGGSNITNYIVEKCDVSR---GDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENR 12574
Query: 488 LVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIIL--DGLDADNTVTVIAGNKLRL 545
I+ LT + F + A+V ++ I + D D+D +I
Sbjct: 12575 FGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIG------ 12628
Query: 546 EIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEA 605
I + +W + + + +R+ YP + +++ E + I N+A
Sbjct: 12629 -YLIERKERNSLLWVKANDTL------VRSTEYPCAG--LVEGLEYS----FRIYALNKA 12675
Query: 606 GEAHASIKVKVVDFP---DPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQ 662
G + S + V DPP P V +V + W P +DGGS I+GYF+E K
Sbjct: 12676 GSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLP 12735
Query: 663 SSRWMRLNF--DLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSP 720
+W+R N + + + E Y+ R A A+ IS PS PS P LA P
Sbjct: 12736 GDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVP 12795
Query: 721 P---------TLLTVDSVT----DTTV------TMRWRPPDHIGAAGLDGYVLEYCFEGS 761
P +LLTV + T D TV T+ W+ DG +L+ EG
Sbjct: 12796 PRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKK---------DGTLLKPA-EGI 12845
Query: 762 TSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEP 821
A Q + E + V KD D T T +++K ++ G
Sbjct: 12846 KMAMQRNL-------CTLELFSVNRKDSGDYT-ITAENSSGSKSATIKLKVLDKPGPPAS 12897
Query: 822 ----KYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVG-EAVNLVIPFQGKPRPELTWKKD 876
K YS ++ EPP + G E N ++ + RP W +
Sbjct: 12898 VKINKMYSDRAMLSW--EPP------------LEDGGSEITNYIVDKRETSRPN--WAQV 12941
Query: 877 GAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ 936
A + ++ R + G D F E A I D PG
Sbjct: 12942 SATVPITSCSVEKLIEGHEYQFRICAENKYGVGD-----PVFTEPA-IAKNPYDPPGRCD 12995
Query: 937 IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATI--TE 994
I ++ +++ ++W PP DDG + ITGY ++K + +++ W T + T+ T
Sbjct: 12996 PPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNW-TKVNRKPIIERTLKATG 13054
Query: 995 LVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNP 1036
L G EY FRV + N G + + +K A ARD + P
Sbjct: 13055 LQEGTEYEFRVTAINKAGPGKPSDASK--AAYARDPQYPPGP 13094
Score = 98.6 bits (244), Expect = 3e-20
Identities = 93/361 (25%), Positives = 149/361 (41%), Gaps = 12/361 (3%)
Query: 271 RFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEK 330
+F E++ +W K QEI ++ G + + I + D+++Y A D+
Sbjct: 5361 KFECEVSREPKTFRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKH 5420
Query: 331 CSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYR 390
S +L + + L+D TA E E+S D+ VKWFKN + +
Sbjct: 5421 TSGKLIIEGIRLKFLTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRL--HTTRSVS 5478
Query: 391 IRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEI 450
++ EGK H + + + D ++ V G S AKL+V L D T E+
Sbjct: 5479 MQDEGKTHSITFKDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEV 5538
Query: 451 CLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYN 509
L+CEIS+ + P KW K+G ++ S + G+ L++ AL D G Y D
Sbjct: 5539 ILQCEISKADAPVKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTC--DCGT 5596
Query: 510 VTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWS-RGDKAIME 568
K+ + D ++ L ++V V+ R E IS E A W +G+ +
Sbjct: 5597 DKTSGKLDIEDREIKLVRPL---HSVEVMETETARFETEIS-EDDIHANWKLKGEALLQT 5652
Query: 569 GSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTV 628
I+ E S LV+ D +G N AH +K +V+ P TV
Sbjct: 5653 PDCEIKEEGKIHS--LVLHNCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTV 5710
Query: 629 T 629
T
Sbjct: 5711 T 5711
Score = 97.1 bits (240), Expect = 9e-20
Identities = 126/568 (22%), Positives = 206/568 (36%), Gaps = 75/568 (13%)
Query: 597 YHINLKNEAGEAHASIKVKVV---DFPDPPVAPTVTEVGDDW---CIMNWEPPAYDGGSP 650
+ + +NE G S+ + V D +PP PT V D + W P YDGG+P
Sbjct: 11971 FRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAP 12030
Query: 651 ILGYFIERKKKQSSR-----WMRLNFDL-CKETTFEPKKMIEGVAYEVRIFAVNAIGISK 704
I+GY +E + K + W R N F + E YE R+ A N +GI +
Sbjct: 12031 IIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGR 12090
Query: 705 PSMPSRPFVPLAVTSPPTLLTVDSVTDTTVT-----------MRWRPPDHIG--AAGLDG 751
P+ P + PP + S+ + +R RP + G+D
Sbjct: 12091 PAELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDN 12150
Query: 752 YVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGL-PTDAK-IFVR 809
V + Q D A+ ++ N D K+++T + P K +FV
Sbjct: 12151 VVRK---------GQVDLVDTMAF------LVIPNSTRDDSGKYSLTLVNPAGEKAVFVN 12195
Query: 810 VKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRP 869
V+ ++ G P+ ++ + K H+ G + + +
Sbjct: 12196 VRVLDTPG---------PVSDLKVSDVTKTSC--HVSWAPPENDGGSQVTHYIVEKREAD 12244
Query: 870 ELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQII 929
TW E+ K ++ N + R + G V V + +
Sbjct: 12245 RKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGP-----GVPTDVPKPVLASDPL 12299
Query: 930 DRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGY-TIQKADKKSMEWFTVIEHYHRT 988
P PP+ +++ ++ + L W PP DG A I GY T + +++ + +T
Sbjct: 12300 SEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDL 12359
Query: 989 SATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPM 1048
S +T L G +Y FRV + N G+S + R+ + VYE + P
Sbjct: 12360 SLVVTGLKEGKKYKFRVAARNAVGVS-----------LPREAE----GVYEAKEQLLPPK 12404
Query: 1049 FTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRK 1108
P T AG + V G P P W K + +V + L I+
Sbjct: 12405 ILMPEQITIK-AGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKD 12463
Query: 1109 PSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
+ D G Y A N GT + K+ V
Sbjct: 12464 VTRKDSGYYSLTAENSSGTDTQKIKVVV 12491
Score = 94.4 bits (233), Expect = 6e-19
Identities = 147/655 (22%), Positives = 260/655 (39%), Gaps = 108/655 (16%)
Query: 20 EEPSKEKEAGTTPAKDWTLVETPPGEEQAKQNANSQLSILFIEKPQGGTVKVGEDITFIA 79
E+ SK E + K T E +A + +S+ I + Q TV F
Sbjct: 26319 EKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVI--VTGLQDTTVSSDSVAKFAV 26376
Query: 80 KVKAEDLLRKPTIKWFK--------GKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIK 131
K E +PT W K GK+ K G L++ +T S +YT ++
Sbjct: 26377 KATGEP---RPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVK--- 26430
Query: 132 AKDNFAGNYR--CEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSGEGQEDAGELD 189
N AG+ C++T K D+ + + +++ TP K++ +E + +
Sbjct: 26431 ---NSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQ-------KKAVVQEEISQKAL 26480
Query: 190 FSGLLKRREVKQQE------EEPQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKRLKR 243
S +K E K QE E +V + E +K + + EK IT
Sbjct: 26481 RSEEIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKTS-------- 26532
Query: 244 MRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHK 303
EE ++ A K +++G R+ +A +VKW NG E+ S +Y +
Sbjct: 26533 QASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGAT-DVKWVLNGVELTNSEEYRYGVS 26591
Query: 304 GCQRILFINNCQMTDDSEYYVTA----GDEKCSTELFVREPPIMVTKQLEDTTAYC---- 355
G + L I D+ + G KC +L ++K+L D A+
Sbjct: 26592 GSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDL-------TLSKELSDAPAFISQPR 26644
Query: 356 ------GERVELECEVS-EDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKA 408
G+ V CE+S E ++WFKN I S I + L I A+ +
Sbjct: 26645 SQNINEGQNVLFTCEISGEPSPEIEWFKNNLPI--SISSNVSISRSRNVYSLEIRNASVS 26702
Query: 409 DAAEYSVMTTG--GQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTK 466
D+ +Y++ GQ SA S+ ++ PL ++ +E+ L+ ++ G ++
Sbjct: 26703 DSGKYTIKAKNFRGQCSATASL------MVLPLVEEP---SREVVLRTSGDTSLQGSFSS 26753
Query: 467 NGLPVQESDR-----------LKVVHKGRIHKLVIANALTEDEGDYVFAPDAY----NVT 511
+ + S + + + + + + + E + ++ N+T
Sbjct: 26754 QSVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMT 26813
Query: 512 ---------LPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRG 562
L A + I PPKI + L +D +++ G L + +GEP P+ WS G
Sbjct: 26814 QLESSTSKMLKAGIRGI-PPKI--EALPSD--ISIDEGKVLTVACAFTGEPTPEVTWSCG 26868
Query: 563 DKAI-MEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKV 616
+ I + GR E+ D +TL+I ++ D G+Y ++L NE G A++ + +
Sbjct: 26869 GRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 26923
Score = 94.0 bits (232), Expect = 7e-19
Identities = 93/416 (22%), Positives = 158/416 (37%), Gaps = 58/416 (13%)
Query: 728 SVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANK 787
+VT +T+ WRPP G A + Y++E E + + +E
Sbjct: 20480 TVTAEKITLLWRPPADDGGAKITHYIVE-----------KRETSRVVWSMVSEH------ 20522
Query: 788 DLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQ 847
+++ T T + + RV+AVN G EP + + P IP K
Sbjct: 20523 --LEECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKI 20580
Query: 848 T-------YIRRVGEAVNLVIPF--QGKPRPELTW---KKDGAEIDKNQINIRNSETDTI 895
T + R + + + + + + + + L W K+ + ++ +D
Sbjct: 20581 TKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQ 20640
Query: 896 IFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPP 955
+ + G + + +F + A ID PGPP ++I D ++ L W+ P
Sbjct: 20641 YRVCAVNAAGQGPFS---EPSEFYKAADP----IDPPGPPAKIRIADSTKSSITLGWSKP 20693
Query: 956 KDDGNAAITGYTIQKADKKSMEWFTVIE--HYHRTSATITELVIGNEYYFRVFSENMCGL 1013
DG +A+TGY ++ + EW TV T ++ L G YYFRV + N G
Sbjct: 20694 VYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQ 20753
Query: 1014 SEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLV---NTYAIAGYNATLNCSV 1070
E M N + D EAP + + A AG + +
Sbjct: 20754 GEPIEM---------------NEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPF 20798
Query: 1071 RGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLG 1126
+G P P +TW K++ + D RY + + L I + + D G Y N +G
Sbjct: 20799 KGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVG 20854
Score = 92.0 bits (227), Expect = 3e-18
Identities = 69/216 (31%), Positives = 100/216 (46%), Gaps = 18/216 (8%)
Query: 930 DRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV-IEHYHRT 988
++PG P I V ++ + W PP DG A I Y ++K +KK +W +V E T
Sbjct: 24326 EKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRET 24385
Query: 989 SATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFS-EAP 1047
++ L+ G EY FRV EN+ G SE + +++ P+ D +AP
Sbjct: 24386 VFSVKNLIEGLEYEFRVKCENLGGESEWSEISE--------------PITPKSDVPIQAP 24431
Query: 1048 MFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMK-NKVAIVDDPRYRMFS-NQGVCTLE 1105
F + L N NATL C V G+PKP + W + K I D +YR+ G L
Sbjct: 24432 HFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLI 24491
Query: 1106 IRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVIAQ 1141
I + D Y +A N G+V LEV+V A+
Sbjct: 24492 IASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAK 24527
Score = 89.4 bits (220), Expect = 2e-17
Identities = 99/438 (22%), Positives = 170/438 (38%), Gaps = 59/438 (13%)
Query: 600 NLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERK 659
N+ ++ + S + +D DPP P + + W P Y GG I Y +E++
Sbjct: 14840 NMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKR 14899
Query: 660 KKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIG-ISKPSMPSRPFVPLAVT 718
+ RW++ NF E F + E AYE R+ A NA G IS PS PS
Sbjct: 14900 DLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDV 14959
Query: 719 SPPTLLTVDSVTDTTVTMRWRPPDHIGA--AGLDGYVLEYCFEGSTSAKQSDENGEAAYD 776
P + VD TV ++ + A +G +E+ +G + G A +
Sbjct: 14960 EAPK-IKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDG------KELEGTAKLE 15012
Query: 777 LPAEDWI--VANKDLI--DKTKFTITGLPTD--AKIFVRVKAVNAAGASEPKYYSQPILV 830
+ D+ + NKD D +T+T AK VK ++ G E P+ V
Sbjct: 15013 IKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPE-----GPLAV 15067
Query: 831 KEIIE--------PPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDK 882
E+ PP + G ++ I Q + L W +E+
Sbjct: 15068 TEVTSEKCVLSWFPP------------LDDGGAKIDHYI-VQKRETSRLAWTNVASEVQV 15114
Query: 883 NQINI-RNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIE 941
++ + + + + IF A + L+ + + P PP+ ++
Sbjct: 15115 TKLKVTKLLKGNEYIFRVMAVNKYGVGEPLE-------SEPVLAVNPYGPPDPPKNPEVT 15167
Query: 942 DVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF-----TVIEHYHRTSATITELV 996
+ +++ + W P DG + I Y +++ DK W T+ + ++ S L
Sbjct: 15168 TITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSG----LT 15223
Query: 997 IGNEYYFRVFSENMCGLS 1014
G+EY FR+ +EN G+S
Sbjct: 15224 EGHEYEFRIMAENAAGIS 15241
Score = 89.0 bits (219), Expect = 2e-17
Identities = 61/198 (30%), Positives = 88/198 (44%), Gaps = 18/198 (9%)
Query: 932 PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSAT 991
P PP+ VK D ++ LTW PPK+DG + I GY +++ + S +W E T
Sbjct: 7091 PDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPVAETKME 7150
Query: 992 ITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAP---M 1048
+T L G Y +RV + N G S+ + T+E + D EAP +
Sbjct: 7151 VTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAV---------------DTQEAPEIFL 7195
Query: 1049 FTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRK 1108
+ L AG L +V G P+PKITW K + + D R + + T+ I
Sbjct: 7196 DVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVD 7255
Query: 1109 PSPYDGGTYCCKAVNDLG 1126
D GTY +AVN G
Sbjct: 7256 SKRSDTGTYIIEAVNVCG 7273
Score = 86.7 bits (213), Expect = 1e-16
Identities = 112/510 (21%), Positives = 197/510 (38%), Gaps = 70/510 (13%)
Query: 648 GSPILGYFIERKKKQSSRWMRLNFDLCKET-TFEPKKMIEGVAYEVRIFAVNAIGISKPS 706
G P+ + R MR N ++ E T K+ + A I A N+ G +K
Sbjct: 20005 GKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAF 20064
Query: 707 MPSRPFVPLAVTSPPT-LLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAK 765
+ V L PPT + + +T+ +VT++W PP + G + + Y+L + TS
Sbjct: 20065 IN---IVVLDRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYIL---LKRETSTA 20118
Query: 766 QSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYS 825
E + +T + L T + R+KA N G S+ S
Sbjct: 20119 VWTEVSAT----------------VARTMMKVMKLTTGEEYQFRIKAENRFGISD-HIDS 20161
Query: 826 QPILVK---EIIEPPKIRIPRHLKQTYI-----RRVGEAVNLVIPF--QGKPRPELTWKK 875
+ VK PP ++ + I V + V+ + + K R + W+K
Sbjct: 20162 ACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQK 20221
Query: 876 DGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETA-----SIDIQIID 930
N++ IR + + S Y+ +V + S + ID
Sbjct: 20222 ------ANKLVIRTTH------FKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAID 20269
Query: 931 RPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV-IEHYHRTS 989
PP+ V+I D+ +V+L+W P DG + ITGY +++ D W + T
Sbjct: 20270 ACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVTETQ 20329
Query: 990 ATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMF 1049
I+ L ++Y FRVF+ N G +++ S V+ P+ D P+
Sbjct: 20330 FIISGLTQNSQYEFRVFARNAVG-----SISNPSEVVG--------PI-TCIDSYGGPVI 20375
Query: 1050 TQPLVNTYAI---AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEI 1106
PL T + AG + L + G P P I W K+ + + + + + ++ I
Sbjct: 20376 DLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILI 20435
Query: 1107 RKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
+ + G Y K N +G+ ++++
Sbjct: 20436 KDADRLNSGCYELKLRNAMGSASATIRVQI 20465
Score = 86.3 bits (212), Expect = 2e-16
Identities = 94/359 (26%), Positives = 158/359 (44%), Gaps = 23/359 (6%)
Query: 285 WYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVT---AGDEKCST-ELFVREP 340
W K+G IR S K+ F G R L I + Q++D EY EK ST +L V E
Sbjct: 4654 WMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEEL 4713
Query: 341 PIMVTKQL-EDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHI 399
P+ K L E+ T G+ + L CE+++ + +V W K+G+ ++ P R V G
Sbjct: 4714 PVRFVKTLEEEVTVVKGQPLYLSCELNK-ERDVVWRKDGKIVVEKP-GRIVPGVIGLMRA 4771
Query: 400 LIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKIL-----TPLTDQTVNLGKEICLKC 454
L I A DA Y+V T ++ + S +K ++++ P+ DQ V C
Sbjct: 4772 LTINDADDTDAGTYTV-TVENANNLECSSCVKVVEVIRDWLVKPIRDQHVKPKGTAIFAC 4830
Query: 455 EISENIPG-KWTK--NGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVT 511
+I+++ P KW K + +P + +D+ +++ G L I NA+ ED +Y A +
Sbjct: 4831 DIAKDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEY--AVEIEGKR 4888
Query: 512 LPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSG 571
PAK+ + + +L ++ VT+ + IS P +G+ ++ S
Sbjct: 4889 YPAKLTLGEREVELLKPIE---DVTIYEKESASFDAEISEADIPGQWKLKGE--LLRPSP 4943
Query: 572 RIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTE 630
++ L + + D +G N A ++K +DF P TV E
Sbjct: 4944 TCEIKAEGGKRFLTLHKVKLDQAGEVLYQALNAITTAILTVKEIELDFAVPLKDVTVPE 5002
Score = 86.3 bits (212), Expect = 2e-16
Identities = 78/292 (26%), Positives = 125/292 (42%), Gaps = 60/292 (20%)
Query: 265 DKGGRVRFV--VELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 322
++GG V++V +E D +V WY +++ S KY ++ IL++ + DD Y
Sbjct: 25083 EEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTY 25142
Query: 323 YVTA----GDEKCSTELFVR---------------------------EPPIMVTKQLEDT 351
G++ ELFV+ E P T L +
Sbjct: 25143 RCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNK 25202
Query: 352 TAYCGERVELECEVS-EDDANVKWFKNGEEIIPGPK-SRYRIRVEGKKHILIIEGATKAD 409
TAY GE V ++ + +V W+K+G++I PG +Y + + L I T D
Sbjct: 25203 TAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDD 25262
Query: 410 AAEYSVMTTG--GQSS--AKLSVDLKPLKILTPLTDQTV-------------NLGKEICL 452
AEY+V+ G+ S AKL+V L P P TD T+ G+ +C
Sbjct: 25263 DAEYTVVARNKYGEDSCKAKLTVTLHP-----PPTDSTLRPMFKRLLANAECQEGQSVCF 25317
Query: 453 KCEISENIPG--KWTKNGLPVQESDRLKVVHKG-RIHKLVIANALTEDEGDY 501
+ +S P KW K+G P+ ++++H+G + L I + L ED G Y
Sbjct: 25318 EIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYY 25369
Score = 85.9 bits (211), Expect = 2e-16
Identities = 115/472 (24%), Positives = 174/472 (36%), Gaps = 92/472 (19%)
Query: 693 RIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGY 752
R AVN + KP P+ P L ++ +T ++ W P G A +D Y
Sbjct: 19374 RSVAVNCKVLDKPGPPAGP------------LEINGLTAEKCSLSWGRPQEDGGADIDYY 19421
Query: 753 VLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKA 812
++E E A W + +L T +T L + RV
Sbjct: 19422 IVE-----------KRETSHLA-------WTICEGEL-QMTSCKVTKLLKGNEYIFRVTG 19462
Query: 813 VNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELT 872
VN G EP + + +K + P L+ T + + E++ L RPE
Sbjct: 19463 VNKYGVGEPL---ESVAIKALDPFTVPSPPTSLEITSVTK--ESMTLCWS-----RPE-- 19510
Query: 873 WKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQI---- 928
G+EI I R E +++ ++R ++ YDL+VK E + ++
Sbjct: 19511 -SDGGSEISGYIIERR--EKNSLRWVRVNKKP---VYDLRVKSTGLREGCEYEYRVYAEN 19564
Query: 929 -------------------IDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQ 969
+ P PP KI D + + W P DG A ITGYT++
Sbjct: 19565 AAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVE 19624
Query: 970 KADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARD 1029
+W T I+ T TI+ L G EY FRV S N G S+ + + D
Sbjct: 19625 YKKSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSS--------D 19676
Query: 1030 GKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVD 1089
+I K E ++ M +V AG + T+ RG P P + W K
Sbjct: 19677 PQIAKEREEEPLFDIDSEMRKTLIVK----AGASFTMTVPFRGRPVPNVLWSKPDT---- 19728
Query: 1090 DPRYRMF--SNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVI 1139
D R R + + +L I + D G Y N L + L VKV+
Sbjct: 19729 DLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASL--TLVVKVL 19778
Score = 85.9 bits (211), Expect = 2e-16
Identities = 128/602 (21%), Positives = 222/602 (36%), Gaps = 112/602 (18%)
Query: 581 SSTLVIDIAERDDSGV--YHINLKNEAGEAH----ASIKVKV------VDFPDPPVAPTV 628
S T I++++ + V + + KNE G + I VK VD D P A
Sbjct: 21018 SKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPITVKELIITPEVDLSDIPGAQVT 21077
Query: 629 TEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKET-TFEPKKMIEG 687
+G + ++ E P P + + + + S ++R + K T + + K G
Sbjct: 21078 VRIGHN---VHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHG 21134
Query: 688 VAYEVRI--------FAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWR 739
Y V + + I + PS P P + D + +V + W
Sbjct: 21135 GKYTVILDNAVCRIAVPITVITLGPPSKPKGP------------IRFDEIKADSVILSWD 21182
Query: 740 PPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITG 799
P+ G + Y +E T+ K + + +T F +
Sbjct: 21183 VPEDNGGGEITCYSIEKRETSQTNWKMVCSS-------------------VARTTFKVPN 21223
Query: 800 LPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNL 859
L DA+ RV+A N G S QP++ I+ + RIP G+ V
Sbjct: 21224 LVKDAEYQFRVRAENRYGVS------QPLVSSIIVAKHQFRIPGP--------PGKPVIY 21269
Query: 860 VIPFQGKPRPELTWKKD----GAEIDKNQINIRNSETDTIIFIRKAERSHSGK------- 908
+ G LTW G+E+ ++ E ++I++ + SG+
Sbjct: 21270 NVTSDGM---SLTWDAPVYDGGSEV--TGFHVEKKERNSILWQKVNTSPISGREYRATGL 21324
Query: 909 -----YDLQVKVDKFVETAS--------IDIQIIDRPGPPQIVKIEDVWGENVALTWTPP 955
Y +V + +S + + +D PG P + DV E + L W PP
Sbjct: 21325 VEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYI---DVTRETITLKWNPP 21381
Query: 956 KDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1015
DG + I GY+I+K T+T L G+ Y FR+ + N G
Sbjct: 21382 LRDGGSKIVGYSIEKRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTIS 21441
Query: 1016 DATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPK 1075
+ + ++ RD + P +F P + L+ +G + + V+G P
Sbjct: 21442 PPSQSS-GIIMTRDENV---PPIVEF----GPEYFDGLIIK---SGESLRIKALVQGRPV 21490
Query: 1076 PKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLE 1135
P++TW K+ V I + G +L +R + G Y +A N G+ + E K++
Sbjct: 21491 PRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVK 21550
Query: 1136 VK 1137
V+
Sbjct: 21551 VQ 21552
Score = 85.5 bits (210), Expect = 3e-16
Identities = 203/971 (20%), Positives = 332/971 (34%), Gaps = 208/971 (21%)
Query: 259 DPAYQVDKGGRVRFVVEL-ADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMT 317
D Y + R + + P V W K + T+ E L + +CQ +
Sbjct: 13492 DLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKS 13551
Query: 318 DDSEYYVT----AGDEKCSTELFVREPPIMVTKQL--EDTTAYC------------GERV 359
D +Y +T AG ++ + + V P + T + ++ TA G +
Sbjct: 13552 DAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEI 13611
Query: 360 ELECEVSEDDANVKWFKNGEEIIPGPKSRYRI-----------RVEGKKHILIIEGATKA 408
D N KW + K+ +R+ RV + + EG
Sbjct: 13612 TNYILEKRDSVNNKWVTCASAV---QKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSE 13668
Query: 409 DAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEIC-LKCEISENIPGKWTK- 466
VD++ + TD G I E E W +
Sbjct: 13669 PIVARHPFDVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRA 13728
Query: 467 NGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIIL 526
N P++ D KV LTE +Y F A N+ K + P + L
Sbjct: 13729 NKTPIRMRD-FKVT------------GLTEGL-EYEFRVMAINLAGVGKPSLPSEPVVAL 13774
Query: 527 DGLDAD----------NTVTVI-------AGNKLRLEIPISGEPPPKAMWSRGDKAIMEG 569
D +D N+VT+I G+KL I + P K+ W + +
Sbjct: 13775 DPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKS-WMKANHV---- 13829
Query: 570 SGRIRTESYPDSSTLVIDIAERDDSGVYH--INLKNEAGEAHA-SIKVKVVDFPDPPVAP 626
+ P+ + V D+ E G Y I KN AG A S + + D AP
Sbjct: 13830 -------NVPECAFTVTDLVE---GGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAP 13879
Query: 627 TVTEVGDDWCIMNWEPPAYDG-----GSPIL--GYFIERKKKQSSRWMRLNFDL----CK 675
T+ +P DG G I+ I K S W + D+
Sbjct: 13880 TIV----------LDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDIT 13929
Query: 676 ETTFEPKKMIEGVAYEVR-------IFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDS 728
+ T P + + Y R I A N G + L V PP + + +
Sbjct: 13930 QITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVK---VTVLDVPGPPGPVEISN 13986
Query: 729 VTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKD 788
V+ T+ W PP G + + Y+LE + TS W V ++D
Sbjct: 13987 VSAEKATLTWTPPLEDGGSPIKSYILE---KRETSRLL---------------WTVVSED 14028
Query: 789 LIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQT 848
I + T L + RV AVN G EP S+P+ + + PP
Sbjct: 14029 -IQSCRHVATKLIQGNEYIFRVSAVNHYGKGEP-VQSEPVKMVDRFGPP----------- 14075
Query: 849 YIRRVGEAVNLVIPFQGKPRPELTWKKD----GAEIDKNQINIRNSETDTIIFIRKAERS 904
G + K ++WK+ G+EI + R E ++ ++R +
Sbjct: 14076 -----GPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERR--EKKSLRWVRAIKTP 14128
Query: 905 HSGKYDLQVKVDKFVETASIDIQIIDR-----------------------PGPPQIVKIE 941
S DL+ KV E ++ + ++ PGPP +
Sbjct: 14129 VS---DLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVT 14185
Query: 942 DVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGN-- 999
D ++ +L W P DG ITGY ++ W I+ T+ IT+ V+ +
Sbjct: 14186 DTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAW---IKDTTGTALRITQFVVPDLQ 14242
Query: 1000 ---EYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNT 1056
+Y FR+ + N G+ E A + D +I + + DF+ L T
Sbjct: 14243 TKEKYNFRISAINDAGVGEPAVIP--------DVEIVEREMAPDFELDAE------LRRT 14288
Query: 1057 YAI-AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGG 1115
+ AG + + ++G P P++TW K+ + + + R + + + L I + + YD G
Sbjct: 14289 LVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKN--RANIENTESFTLLIIPECNRYDTG 14346
Query: 1116 TYCCKAVNDLG 1126
+ N G
Sbjct: 14347 KFVMTIENPAG 14357
Score = 85.1 bits (209), Expect = 3e-16
Identities = 105/480 (21%), Positives = 179/480 (37%), Gaps = 70/480 (14%)
Query: 672 DLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTD 731
D C+E + A E I +N I + KP P+ P + +D VT
Sbjct: 15712 DACREDVGHYVVKLTNSAGEA-IETLNVIVLDKPGPPTGP------------VKMDEVTA 15758
Query: 732 TTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLID 791
++T+ W PP + G + ++ Y++E D W + + +
Sbjct: 15759 DSITLSWGPPKYDGGSSINNYIVE------------------KRDTSTTTWQIVSAT-VA 15799
Query: 792 KTKFTITGLPTDAKIFVRVKAVNAAGAS-----EPKYYSQPILVKEIIEPPKIRIPRH-- 844
+T L T + R+ A N G S EP P V P + +
Sbjct: 15800 RTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDS 15859
Query: 845 LKQTYIRRVGEAVNLVIPF--QGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAE 902
++ + + + + VI + + K R + W K ++K I +T + + E
Sbjct: 15860 MEVQWNEPISDGGSRVIGYHLERKERNSILWVK----LNKTPIPQTKFKTTGLEEGVEYE 15915
Query: 903 RSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAA 962
S + + + V + D PG P+ + + +V L W P DG +
Sbjct: 15916 FRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIIVTR---NSVTLQWKKPTYDGGSK 15972
Query: 963 ITGYTIQKADKKSMEWFTV-IEHYHRTSATITELVIGNEYYFRVFSENMCGL-SEDATMT 1020
ITGY ++K + W + T +T LV + Y FRV + N G+ SE + T
Sbjct: 15973 ITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSEST 16032
Query: 1021 KESAVIARDG----KIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKP 1076
A+ ARD +I +P Y+D AG + ++ + G P P
Sbjct: 16033 --GAITARDEVDPPRISMDPKYKD--------------TIVVHAGESFKVDADIYGKPIP 16076
Query: 1077 KITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
I W+K + + R + S +L ++ D G Y KA N G + ++V
Sbjct: 16077 TIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKV 16136
Score = 85.1 bits (209), Expect = 3e-16
Identities = 100/435 (22%), Positives = 171/435 (39%), Gaps = 65/435 (14%)
Query: 720 PPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPA 779
PP + +D V+ ++T+ W PP++ G + Y++E ST+
Sbjct: 18993 PPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTT---------------- 19036
Query: 780 EDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPP-- 837
W + ++ + +T I L T ++ RV A N G S S ++ + PP
Sbjct: 19037 --WHIVSQ-AVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSE-SSAVVAEYPFSPPGP 19092
Query: 838 --KIRIPRHLKQTYIRR----VGEAVNLVIPF--QGKPRPELTWKKDGAEIDKNQINIRN 889
++ K T + V + + VI + + K R + W K N+I I
Sbjct: 19093 PGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSK------ANKILI-- 19144
Query: 890 SETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQII------DRPGPPQIVKIEDV 943
DT + + + +Y + + + S + + D PG P++ I
Sbjct: 19145 --ADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTNITR- 19201
Query: 944 WGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV-IEHYHRTSATITELVIGNEYY 1002
++V+L W+ P DG A ITGY +++ + W + T +TEL Y
Sbjct: 19202 --KSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFEVTELTEDQRYE 19259
Query: 1003 FRVFSENMC-GLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAG 1061
FRVF+ N +SE + T +I +D + V D F + + AG
Sbjct: 19260 FRVFARNAADSVSEPSEST--GPIIVKDD-VEPPRVMMDVKFRDVIVVK---------AG 19307
Query: 1062 YNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKA 1121
+N + G P P I+W K+ + I + R + S L ++ D G Y
Sbjct: 19308 EVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTL 19367
Query: 1122 VNDLGT--VEIECKL 1134
N GT V + CK+
Sbjct: 19368 KNVAGTRSVAVNCKV 19382
Score = 84.0 bits (206), Expect = 8e-16
Identities = 100/460 (21%), Positives = 169/460 (36%), Gaps = 78/460 (16%)
Query: 697 VNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEY 756
+ + + P P PF + + ++ W P G + + Y++E
Sbjct: 12487 IKVVVMDAPGPPQPPF------------DISDIDADACSLSWHIPLEDGGSNITNYIVEK 12534
Query: 757 CFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAA 816
C D+ DW+ A + KT + L + RV+A N
Sbjct: 12535 C------------------DVSRGDWVTALAS-VTKTSCRVGKLIPGQEYIFRVRAENRF 12575
Query: 817 GASEPKYYSQPILVKEI-----IEPPKIRIPRHLKQ----TYIRRVGEAVNLVIPF--QG 865
G SEP + P +V + EP R+ + K + R + + +I + +
Sbjct: 12576 GISEP--LTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIER 12633
Query: 866 KPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERS------HSGKYDLQVKVDKFV 919
K R L W K N +R++E + E S + K ++V
Sbjct: 12634 KERNSLLWVK------ANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYV 12687
Query: 920 ETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF 979
TA + + D PG P+++ DV V+L W PK DG + I GY ++ +W
Sbjct: 12688 -TARMPV---DPPGKPEVI---DVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWV 12740
Query: 980 ---TVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNP 1036
T + T T L +Y FR + +S + + ++A + P
Sbjct: 12741 RCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENV-----P 12795
Query: 1037 VYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMF 1096
D + + T AG N L+ +V G P P ++W K+ + +M
Sbjct: 12796 PRIDLSVAMKSLLTVK-------AGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMA 12848
Query: 1097 SNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
+ +CTLE+ + D G Y A N G+ KL+V
Sbjct: 12849 MQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKV 12888
Score = 82.8 bits (203), Expect = 2e-15
Identities = 59/194 (30%), Positives = 92/194 (47%), Gaps = 21/194 (10%)
Query: 547 IPISGEPPPKAMWSRGDKAIMEGSGRIRTE-------SYPDSSTLVIDIAERDDSGVYHI 599
+ + EPP + ++E R+ T + PD + V D+ E + + +
Sbjct: 7703 VDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQ-FQV 7761
Query: 600 NLKNEAGEAHASIKVKVVDFPDPPVAPT------VTEVGDDWCIMNWEPPAYDGGSPILG 653
+NEAG H S +++ DP P+ VT+ G + W+PP +GGSPI+G
Sbjct: 7762 RAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIG 7821
Query: 654 YFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVA----YEVRIFAVNAIGISKPSMPS 709
Y +E + +WMR+N K+ F K+ EGV Y +R+ AVNAIG+S+PS S
Sbjct: 7822 YHVEMCPVGTEKWMRVNSRPIKDLKF---KVEEGVVPDKEYVLRVRAVNAIGVSEPSEIS 7878
Query: 710 RPFVPLAVTSPPTL 723
V PT+
Sbjct: 7879 ENVVAKDPDCKPTI 7892
Score = 80.9 bits (198), Expect = 6e-15
Identities = 77/261 (29%), Positives = 107/261 (40%), Gaps = 22/261 (8%)
Query: 464 WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPD--AYNVTLPAKVHVIDP 521
W K+G V+ SDRL + + L + ++ D G Y + + T V VI
Sbjct: 7923 WHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGL 7982
Query: 522 PKIILDGLDADNTVTVIAGNKLRLEIP--ISGEPPPKAMWSRGDKA------IMEGSGRI 573
P D +D T + KL E P G P + R + +M G ++
Sbjct: 7983 PGPCKDIKASDITK---SSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKL 8039
Query: 574 R---TESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTE 630
+ P+ A G +I LKN I PDPPV V
Sbjct: 8040 SWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPV------IAQDPKQPPDPPVDVEVHN 8093
Query: 631 VGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAY 690
+ + W+PP YDGGS I+GY IE+ K RW R N L T+ K + EG Y
Sbjct: 8094 PTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEY 8153
Query: 691 EVRIFAVNAIGISKPSMPSRP 711
+ R+ A NA GIS+PS + P
Sbjct: 8154 QFRVRAENAAGISEPSRATPP 8174
Score = 77.8 bits (190), Expect = 5e-14
Identities = 66/264 (25%), Positives = 116/264 (43%), Gaps = 27/264 (10%)
Query: 263 QVDKGGRVRFVVELADPKLEVKWYKNGQEI----RPSTKYIFEHKGCQRILFINNCQMTD 318
QV + R E+ + ++ WYK+G EI + KY+ E + +FI+ + +D
Sbjct: 3111 QVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERR--IHRMFISETRQSD 3168
Query: 319 DSEYYVTAGDEKCSTELFVREP-PIMVTKQLEDTTAYCGERVELECEVS-EDDANVKWFK 376
EY AG + S L+V P P V ++L+ T G+ +S + W+K
Sbjct: 3169 AGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYK 3228
Query: 377 NGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAA--------EYSVMTTGGQSSAKL-- 426
+ + G K ++ +G+++ L++ A DAA +Y V TT S ++
Sbjct: 3229 EEQLLSTGFKCKF--LHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPE 3286
Query: 427 ------SVDLKPLKILTPLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKV 479
+ + P I+TPL D + G+ +C +S ++ W ++ S ++
Sbjct: 3287 VVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRM 3346
Query: 480 VHKGRIHKLVIANALTEDEGDYVF 503
++L IA A EDEG Y F
Sbjct: 3347 TQFEDTYQLEIAEAYPEDEGTYTF 3370
Score = 77.8 bits (190), Expect = 5e-14
Identities = 104/452 (23%), Positives = 164/452 (36%), Gaps = 62/452 (13%)
Query: 697 VNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEY 756
++ I + KP P P + D V+ V + W PP + G + Y++E
Sbjct: 17900 LSVIVLEKPGPPVGP------------VRFDEVSADFVVISWEPPAYTGGCQISNYIVE- 17946
Query: 757 CFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAA 816
D W + + + +T IT L T + R+ A N
Sbjct: 17947 -----------------KRDTTTTTWHMVSAT-VARTTIKITKLKTGTEYQFRIFAENRY 17988
Query: 817 GASEPKYYSQPILV----KEIIEPPKIRIPRHLKQTYIRRVGEAVN------LVIPFQGK 866
G S P S+ ++V KE P + K + + E VN + + K
Sbjct: 17989 GKSAP-LDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQK 18047
Query: 867 PRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDI 926
+ + W K ++K I +T + + E S + + + V +
Sbjct: 18048 EKNSILWVK----LNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVAR 18103
Query: 927 QIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV-IEHY 985
D PG P+ + I NV L W P DG + ITGY ++K D W +
Sbjct: 18104 DPCDPPGRPEAIVITR---NNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNV 18160
Query: 986 HRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSE 1045
T T++ LV Y FRV + N G + + A+ ARD N +
Sbjct: 18161 LETEFTVSGLVEDQRYEFRVIARNAAGNFSEPS-DSSGAITARDEIDAPNASLD------ 18213
Query: 1046 APMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDD-PRYRMFSNQGVCTL 1104
P + +V AG L +RG P P + W K+ + + R + S TL
Sbjct: 18214 -PKYKDVIV---VHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTL 18269
Query: 1105 EIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
++ DGG Y K N GT I ++V
Sbjct: 18270 VVKDCIRTDGGQYILKLSNVGGTKSIPITVKV 18301
Score = 77.4 bits (189), Expect = 7e-14
Identities = 102/462 (22%), Positives = 169/462 (36%), Gaps = 81/462 (17%)
Query: 696 AVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLE 755
++ + + KP P P + D V+ ++T+ W PP + G + Y+++
Sbjct: 16817 SIEIVTLDKPDPPKGP------------VKFDDVSAESITLSWNPPLYTGGCQITNYIVQ 16864
Query: 756 YCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNA 815
D W V + + +T +T L T + R+ A N
Sbjct: 16865 ------------------KRDTTTTVWDVVSAT-VARTTLKVTKLKTGTEYQFRIFAENR 16905
Query: 816 AGASEPKYYSQPILVKEIIE---PPKIRIPRHL-KQTYIRRVGEAVN------LVIPFQG 865
G S S PI+ + + PP + K + + + E VN + +
Sbjct: 16906 YGQSFA-LESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLER 16964
Query: 866 KPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSG-KYDLQVKVDKFVETAS- 923
K R + W K ++K I+ DT KA+ G +Y+ +V + V
Sbjct: 16965 KERNSILWTK----VNKTIIH------DTQF---KAQNLEEGIEYEFRVYAENIVGVGKA 17011
Query: 924 -------IDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSM 976
+ D PG P+ + ++ + L WT P DG + ITGY ++K D
Sbjct: 17012 SKNSECYVARDPCDPPGTPEPIMVKR---NEITLQWTKPVYDGGSMITGYIVEKRDLPDG 17068
Query: 977 EWFTV-IEHYHRTSATITELVIGNEYYFRVFSENMCG-LSEDATMTKESAVIARDGKIYK 1034
W + T T++ L Y FRV ++N G +S+ + T G I
Sbjct: 17069 RWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDST---------GPITA 17119
Query: 1035 NPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYR 1094
E S P F +V AG L V G P P I W++ I + R
Sbjct: 17120 KDEVELPRISMDPKFRDTIVVN---AGETFRLEADVHGKPLPTIEWLRGDKEIEESARCE 17176
Query: 1095 MFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
+ + L ++ DGG Y +A N G+ ++V
Sbjct: 17177 IKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKV 17218
Score = 77.0 bits (188), Expect = 9e-14
Identities = 106/469 (22%), Positives = 169/469 (36%), Gaps = 97/469 (20%)
Query: 697 VNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEY 756
+ I + KP P+ P + +D + T++T+ W PP+ G A L GYV+E
Sbjct: 23327 IKVIILDKPGPPTGP------------IKIDEIDATSITISWEPPELDGGAPLSGYVVEQ 23374
Query: 757 CFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAA 816
D W+ ++ + ++ F T L + RV A N
Sbjct: 23375 ------------------RDAHRPGWLPVSES-VTRSTFKFTRLTEGNEYVFRVAATNRF 23415
Query: 817 GASEPKYYSQPILVKEIIE-PPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTW-- 873
G L E+IE IRIP G L I + LTW
Sbjct: 23416 GIGS-------YLQSEVIECRSSIRIP-----------GPPETLQIFDVSRDGMTLTWYP 23457
Query: 874 -KKDGAE------IDKNQINIR-----NSETDTIIFIRKAERSHSGKYDLQVKVDKFVET 921
+ DG +++ ++ N T+ R + +Y+ +V +
Sbjct: 23458 PEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGS 23517
Query: 922 AS--------IDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADK 973
+ + I PG PQ ++ D +V+L W+ P+D+G + +TGY I+
Sbjct: 23518 GKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKV 23577
Query: 974 KSMEWF------TVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIA 1027
EW T I Y T+T L G EY FRV + N G E A +
Sbjct: 23578 DQHEWTKCNTTPTKIREY-----TLTHLPQGAEYRFRVLACNAGGPGEPAE-------VP 23625
Query: 1028 RDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAI 1087
K+ + Y D++ E + + G L ++G P P W K I
Sbjct: 23626 GTVKVTEMLEYPDYELDE-----RYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDI 23680
Query: 1088 VDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
R + +++ L I++ D GTY N G + K+ V
Sbjct: 23681 --SKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRV 23727
Score = 73.9 bits (180), Expect = 8e-13
Identities = 64/235 (27%), Positives = 91/235 (38%), Gaps = 46/235 (19%)
Query: 932 PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRT-SA 990
P PP V++ + E + +TW PP DG + I GY I+K K W EH +
Sbjct: 8083 PDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTY 8142
Query: 991 TITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFT 1050
T L G EY FRV +EN G+SE + T + + + D + + T
Sbjct: 8143 TAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAV------------DPIDAPKVILRT 8190
Query: 1051 QPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDD-------PRYRM-------- 1095
V G L+ S+ G+P P ITW+K++ IV + P R
Sbjct: 8191 SLEVKR----GDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEE 8246
Query: 1096 --------------FSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
S +G L +R D G Y K ND G + C + V
Sbjct: 8247 EPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSV 8301
Score = 73.9 bits (180), Expect = 8e-13
Identities = 59/203 (29%), Positives = 83/203 (40%), Gaps = 14/203 (6%)
Query: 926 IQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHY 985
++ + P PP + I D+ V+L W PK DG + ITGY I+ K S +W T I
Sbjct: 14462 VKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQW-THITTV 14520
Query: 986 HRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSE 1045
+ L G EY F+V + N G S +ES + + + + + D
Sbjct: 14521 KGLECVVRNLTEGEEYTFQVMAVNSAGRSAP----RESRPVI----VKEQTMLPELDLRG 14572
Query: 1046 APMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLE 1105
Q LV A AG N + V G PKP +TW K + R + L
Sbjct: 14573 ---IYQKLV--IAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILN 14627
Query: 1106 IRKPSPYDGGTYCCKAVNDLGTV 1128
I + D G Y A N +G V
Sbjct: 14628 INECVRSDSGPYPLTARNIVGEV 14650
Score = 73.2 bits (178), Expect = 1e-12
Identities = 52/197 (26%), Positives = 86/197 (43%), Gaps = 13/197 (6%)
Query: 930 DRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTS 989
++P PP+ + + D + L W P DG + ITGY ++ K S W H + +
Sbjct: 22047 EQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEA-GHTKQLT 22105
Query: 990 ATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMF 1049
T+ LV EY FRV ++N G SE S+VI ++ +I ++
Sbjct: 22106 FTVERLVEKTEYEFRVKAKNDAGYSEPREAF--SSVIIKEPQIEPT--------ADLTGI 22155
Query: 1050 TQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKP 1109
T L+ A G T++ + G P PK+TW ++ + + R + + + TL ++
Sbjct: 22156 TNQLITCKA--GSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDS 22213
Query: 1110 SPYDGGTYCCKAVNDLG 1126
D G Y N G
Sbjct: 22214 MRGDSGRYFLTLENTAG 22230
Score = 72.4 bits (176), Expect = 2e-12
Identities = 56/222 (25%), Positives = 101/222 (45%), Gaps = 17/222 (7%)
Query: 918 FVETASIDI--QIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKS 975
FVET+ + + I P P+ +++++V V LTW PPK DG + I Y ++ +
Sbjct: 10204 FVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGT 10263
Query: 976 MEWFTVI-EHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYK 1034
++ V ++ T+ L G+ Y +RV + N+ G + + TK I ++
Sbjct: 10264 EKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKP---ITCKDELAP 10320
Query: 1035 NPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYR 1094
++ DF T + +A+ G + G PKPK++W K++ +++D R
Sbjct: 10321 PTLHLDF----RDKLTIRVGEAFALTGRYS-------GKPKPKVSWFKDEADVLEDDRTH 10369
Query: 1095 MFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
+ + LE K D G YC N G+ + C++ V
Sbjct: 10370 IKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNV 10411
Score = 71.6 bits (174), Expect = 4e-12
Identities = 134/663 (20%), Positives = 230/663 (34%), Gaps = 120/663 (18%)
Query: 2 PEPTKKEENEVPAP----APPPEEPSKEKEAGTTPAKDWTLVETPPGEEQAKQNANSQLS 57
PEP K V +P +P P P T P TP + Q +
Sbjct: 26172 PEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKP--------TPTEKVQHLPVSAPPKI 26223
Query: 58 ILFIEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAGKHLQLKETFE 117
F++ + ++I + V +LR + W+K GK L+ F+
Sbjct: 26224 TQFLK------AEASKEIAKLTCVVESSVLRAKEVTWYKD---------GKKLKENGHFQ 26268
Query: 118 RH-SRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFK 176
H S T+E++I ++ G Y CE+
Sbjct: 26269 FHYSADGTYELKINNLTESDQGEYVCEI-------------------------------- 26296
Query: 177 RSGEGQEDAGELDFSG---------LLKRREVKQQEEEPQVDVWELLKNAKPSEYEKIAF 227
SGEG L F G + K E K+ +++ + + +P E I+
Sbjct: 26297 -SGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTEST--VTRKTEPKAPEPIS- 26352
Query: 228 QYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYK 287
K + D D + V +P+ W K
Sbjct: 26353 ---------------------SKPVIVTGLQDTTVSSDSVAKFA-VKATGEPRPTAIWTK 26390
Query: 288 NGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVT----AGDEKCSTELFVREPPIM 343
+G+ I KY L I+ +D Y T AG S +L ++ I
Sbjct: 26391 DGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKA--IK 26448
Query: 344 VTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIE 403
T+ + +T E + V +++ + K ++ E + KS+ ++ ++ + ++I
Sbjct: 26449 DTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLALKEEASKVLIS 26508
Query: 404 GATKADAA---EYSVMTTGGQSSAKLSVDLKP-LKILTPLTDQTVNLGKEICLKCEISEN 459
K AA E S++ +++ S +++ +I T ++N G+ + LK I+
Sbjct: 26509 EEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGA 26568
Query: 460 IPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV--------FAPDAYNVT 511
KW NG+ + S+ + G L I A DEG Y++T
Sbjct: 26569 TDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLT 26628
Query: 512 LPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSG 571
L ++ D P I + + G + ISGEP P+ W + + I S
Sbjct: 26629 LSKELS--DAPAFI----SQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPI-SISS 26681
Query: 572 RIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEV 631
+ + +L I A DSG Y I KN G+ A+ + V+ + P V
Sbjct: 26682 NVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRT 26741
Query: 632 GDD 634
D
Sbjct: 26742 SGD 26744
Score = 68.9 bits (167), Expect = 3e-11
Identities = 107/465 (23%), Positives = 175/465 (37%), Gaps = 76/465 (16%)
Query: 696 AVNAIGISKPSMPSR-PFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVL 754
A NA G +K + + P V P + ++T +T+ W P + G A + Y++
Sbjct: 21536 AKNASGSAKAEIKVKVQDTPGKVVGP---IRFTNITGEKMTLWWDAPLNDGCAPITHYII 21592
Query: 755 EYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVN 814
E E A+ L +D + +T L + RV AVN
Sbjct: 21593 E-----------KRETSRLAWALI--------EDKCEAQSYTAIKLINGNEYQFRVSAVN 21633
Query: 815 AAGASEPKYYSQPILVK---EIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPEL 871
G P S P++ + + + P I P ++ G ++ L RPE
Sbjct: 21634 KFGVGRP-LDSDPVVAQIQYTVPDAPGIPEPSNI-------TGNSITLTWA-----RPE- 21679
Query: 872 TWKKDGAEIDKNQINIRNSE-TDTIIFIRKAERSHS----------GKYDLQVKVDKF-- 918
G+EI + + R + T + I K S + +Y+ V +
Sbjct: 21680 --SDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAG 21737
Query: 919 VETASIDIQII------DRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKAD 972
V AS ++I + PGPP +VK+ D V+L W+ P DG I GY I+
Sbjct: 21738 VGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCK 21797
Query: 973 KKSMEWFTV-IEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGK 1031
+W V E +T T+T+L G EY FRV + N G + +T I +
Sbjct: 21798 ADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVT---GTIKAVDR 21854
Query: 1032 IYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDP 1091
+ + D +F + + AG + L + +G P P W K +
Sbjct: 21855 LTAPELDIDANFKQTHVVR---------AGASIRLFIAYQGRPTPTAVWSKPDSNL--SL 21903
Query: 1092 RYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
R + + TL + + D G Y N+ G+ I ++V
Sbjct: 21904 RADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKV 21948
Score = 64.7 bits (156), Expect = 5e-10
Identities = 75/303 (24%), Positives = 129/303 (42%), Gaps = 19/303 (6%)
Query: 341 PIMVTKQLEDT----TAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGK 396
P+ K+++D + + G EC VS A W K+G I PK +R +GK
Sbjct: 4617 PLKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPK--HRFIADGK 4674
Query: 397 KHILIIEGATKADAAEYSVMTTGGQ----SSAKLSVDLKPLKILTPLTDQ-TVNLGKEIC 451
L I +DA EY+ + G S+AKL V+ P++ + L ++ TV G+ +
Sbjct: 4675 DRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLY 4734
Query: 452 LKCEISENIPGKWTKNG-LPVQESDRLKVVHKGRIHKLVIANALTEDEGDY-VFAPDAYN 509
L CE+++ W K+G + V++ R+ G + L I +A D G Y V +A N
Sbjct: 4735 LSCELNKERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVENANN 4794
Query: 510 VTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEG 569
+ + V V++ +I D L + + + P W +G I
Sbjct: 4795 LECSSCVKVVE---VIRDWLVKPIRDQHVKPKGTAIFACDIAKDTPNIKWFKGYDEI-PA 4850
Query: 570 SGRIRTESYPDSSTLVIDI--AERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT 627
+TE D + L + I A +D Y + ++ + A ++ + V+ P T
Sbjct: 4851 EPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGKRYPAKLTLGEREVELLKPIEDVT 4910
Query: 628 VTE 630
+ E
Sbjct: 4911 IYE 4913
Score = 63.5 bits (153), Expect = 1e-09
Identities = 31/92 (33%), Positives = 43/92 (46%)
Query: 1047 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEI 1106
P L N I G + TL C + G P P +TW + I +++ G+ L I
Sbjct: 897 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMI 956
Query: 1107 RKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1138
R+ D G + C AVN+ GTV C L V+V
Sbjct: 957 REAFAEDSGRFTCSAVNEAGTVSTSCYLAVQV 988
Score = 61.2 bits (147), Expect = 5e-09
Identities = 33/100 (33%), Positives = 54/100 (54%), Gaps = 6/100 (6%)
Query: 931 RPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEH-YHRTS 989
RP PP++ K+ E + + W PP+ DG +ITGY ++K +K S W V +
Sbjct: 11901 RPDPPEVTKVSK---EEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERR 11957
Query: 990 ATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARD 1029
+ L+ +EY FRV +EN G+ E + ++ V+A+D
Sbjct: 11958 MKVQNLLPDHEYQFRVKAENEIGIGEPSLPSR--PVVAKD 11995
Score = 59.7 bits (143), Expect = 2e-08
Identities = 74/324 (22%), Positives = 129/324 (39%), Gaps = 19/324 (5%)
Query: 829 LVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQ--GKPRPELTWKKDGAEID----- 881
L +E P + P + + ++++ E ++V Q G P+P + WKK G +
Sbjct: 1023 LTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRY 1082
Query: 882 KNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIE 941
K N + E +I + A+ +G+Y + V+ +K ET S +++ ++K +
Sbjct: 1083 KVSYNKQTGECKLVISMTFAD--DAGEYTIVVR-NKHGET-SASASLLEEADYELLMKSQ 1138
Query: 942 DVWGENVALTWTPPKDDGNAAITGYTIQKADKK-SMEWFTVIEHYHRTSATITELVIGNE 1000
+T + G+ + +K+ E + + + + + V E
Sbjct: 1139 QEMLYQTQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDTVVVRTYVEDQE 1198
Query: 1001 YYFRVFSENMCGLSEDATM-TKESAVIARDGKIYKNPVYEDFDFSEAPM--FTQPLVNTY 1057
++ F E + E + T ++ DG+ + D SEA F + N
Sbjct: 1199 FHISSFEERLIKEIEYRIIKTTLEELLEEDGE---EKMAVDISESEAVESGFDSRIKNYR 1255
Query: 1058 AIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRM-FSNQGVCTLEIRKPSPYDGGT 1116
+ G T +C + G P PKI W K+ I RY+M F G +L I P D G
Sbjct: 1256 ILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGI 1315
Query: 1117 YCCKAVNDLGTVEIECKLEVKVIA 1140
Y A N G KL V+ A
Sbjct: 1316 YTAFASNIKGNAICSGKLYVEPAA 1339
Score = 59.3 bits (142), Expect = 2e-08
Identities = 96/426 (22%), Positives = 148/426 (34%), Gaps = 58/426 (13%)
Query: 717 VTSPPT-LLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAY 775
+ PPT + D V+ VT W PP++ G + YV+E ST+
Sbjct: 14661 IPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTT------------ 14708
Query: 776 DLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIE 835
W+ +I +T + T L T + RVKA N G P S I+
Sbjct: 14709 ------WVELATTVI-RTTYKATRLTTGLEYQFRVKAQNRYGVG-PGITSACIVANY--- 14757
Query: 836 PPKIRIPRHLKQ-TYIRRVGEAVNLVIPF------------QGKPRPELTWKKDGAEIDK 882
P K+ P Q T + + ++ P + K R + W+ +
Sbjct: 14758 PFKVPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVP 14817
Query: 883 NQINIRNSETDTIIF-IRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIE 941
I + TD I + R + +GK K K E + + ID PG P + I
Sbjct: 14818 GNIFKSSGLTDGIAYEFRVIAENMAGKS----KPSKPSEPM-LALDPIDPPGKPVPLNIT 14872
Query: 942 DVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV-IEHYHRTSATITELVIGNE 1000
V L W P+ G IT Y ++K D + W + T++ L
Sbjct: 14873 R---HTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAA 14929
Query: 1001 YYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIA 1060
Y FRV ++N G + ++ D + K V D F + + A
Sbjct: 14930 YEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKV--DVKFKDTVILK---------A 14978
Query: 1061 GYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCK 1120
G L V G P P + W K+ + + + L + + D G Y
Sbjct: 14979 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLT 15038
Query: 1121 AVNDLG 1126
A N G
Sbjct: 15039 ATNPGG 15044
Score = 57.4 bits (137), Expect = 8e-08
Identities = 95/406 (23%), Positives = 148/406 (36%), Gaps = 54/406 (13%)
Query: 694 IFAVNAIGISKPSMPSRPFVPLAVTSPPT-LLTVDSVTDTTVTMRWRPPDHIGAAGLDGY 752
I AVN +G + M L PP + +SV+ +T+ W PP G + + Y
Sbjct: 9699 ITAVNNLGTASKEMRLNV---LGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNY 9755
Query: 753 VLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKA 812
V+E + + W+ + + + T +TI L + R+ A
Sbjct: 9756 VIE------------------KREANRKTWVHVSSEPKECT-YTIPKLLEGHEYVFRIMA 9796
Query: 813 VNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIP-FQGKPRPEL 871
N G EP S+P + + P P + + R VN P + G
Sbjct: 9797 QNKYGIGEP-LDSEPETARNLFSVPGA--PDKPTVSSVTRNSMTVNWEEPEYDGGSPVTG 9853
Query: 872 TW--KKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKF----VETASID 925
W KD ++N + T+ K G D Q +V V AS+
Sbjct: 9854 YWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEGS-DYQFRVYAINAAGVGPASLP 9912
Query: 926 IQI------IDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF 979
I PGPP K+ D + L W+PP DG + +TGY ++ ++ EW
Sbjct: 9913 SDPATARDPIAPPGPP-FPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWE 9971
Query: 980 TVIEHYHR-TSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVY 1038
+ R T +T L G Y FRV + N+ G+ E +T VI ++ +
Sbjct: 9972 KGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTD---VIEMKDRLVSPDLQ 10028
Query: 1039 EDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNK 1084
D + AG + V G P P +TW N+
Sbjct: 10029 LDASVRD---------RIVVHAGGVIRIIAYVSGKPPPTVTWNMNE 10065
Score = 57.0 bits (136), Expect = 1e-07
Identities = 43/167 (25%), Positives = 72/167 (43%), Gaps = 11/167 (6%)
Query: 345 TKQLEDTTAYCGERVELECEVSEDDA-NVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIE 403
T+ L+ G E +S V WF++G+ I +I + L I
Sbjct: 9 TQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIP 68
Query: 404 GATKADAAEYSVMTTGGQSSAKLSVDL------KPLKILTPLTDQTVNLGKEICLKCEIS 457
TKA++ YS+ T G A + +L P + L TV G ++ L+ ++
Sbjct: 69 AVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVT 128
Query: 458 ENIPG---KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 501
IP K+ ++G +Q S ++ +G ++ L+IA A ED G Y
Sbjct: 129 -GIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTY 174
Score = 56.6 bits (135), Expect = 1e-07
Identities = 39/140 (27%), Positives = 56/140 (40%), Gaps = 9/140 (6%)
Query: 1003 FRVFSENMCGLSEDATM---TKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI 1059
F+ E + +SE T ES V + P+ S P+ L +T
Sbjct: 26314 FKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPI------SSKPVIVTGLQDTTVS 26367
Query: 1060 AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCC 1119
+ A G P+P W K+ AI +Y++ ++G LEI K D G Y C
Sbjct: 26368 SDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTC 26427
Query: 1120 KAVNDLGTVEIECKLEVKVI 1139
N G+V CKL +K I
Sbjct: 26428 TVKNSAGSVSSSCKLTIKAI 26447
Score = 56.6 bits (135), Expect = 1e-07
Identities = 74/348 (21%), Positives = 121/348 (34%), Gaps = 77/348 (22%)
Query: 865 GKPRPELTWKKDGAEIDKN-QINIRNSETDTIIFIRKAERSHSGKYD------------- 910
G+PRP W KDG I + + + + + I K + S SG Y
Sbjct: 26380 GEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSS 26439
Query: 911 --LQVKVDKFVETASIDIQIIDRPGPPQIVKIED------VWGENVALTWTPP------K 956
L +K K E + Q P + +++ + E + ++ K
Sbjct: 26440 CKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLALK 26499
Query: 957 DDGNAAITGYTIQKADKKSMEWFTVIEHYHRTS-------------ATITELVIGNEYYF 1003
++ + + ++K+ S+E V E +TS A T++ I NE
Sbjct: 26500 EEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSI-NEGQR 26558
Query: 1004 RVFSENMCGLSE-----------------------DATMT------KESAVIARDGKIYK 1034
V N+ G ++ D T+T ++ ++ K +
Sbjct: 26559 LVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKE 26618
Query: 1035 NPVYEDFDF------SEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIV 1088
V +D S+AP F + G N C + G P P+I W KN + I
Sbjct: 26619 GIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPIS 26678
Query: 1089 DDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
+ ++ V +LEIR S D G Y KA N G L V
Sbjct: 26679 ISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 26726
Score = 54.7 bits (130), Expect = 5e-07
Identities = 52/221 (23%), Positives = 77/221 (34%), Gaps = 45/221 (20%)
Query: 920 ETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF 979
+TA D++++ RP P E W DG + YT +
Sbjct: 1426 QTARFDLKVVGRPMP------ETFWFH-----------DGQQIVNDYTHK---------- 1458
Query: 980 TVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYE 1039
VI+ S I + + V ++N G S + + AV
Sbjct: 1459 VVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAV-------------- 1504
Query: 1040 DFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDD--PRYRMFS 1097
+ PMF + L N G + GNP P I W+KN IV P+ R+
Sbjct: 1505 --EHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEG 1562
Query: 1098 NQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1138
+G L+I D Y A+N G CK+ V+V
Sbjct: 1563 TKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEV 1603
Score = 51.2 bits (121), Expect = 5e-06
Identities = 56/305 (18%), Positives = 122/305 (40%), Gaps = 22/305 (7%)
Query: 842 PRHLKQTYIRRVGEAVNLVIPFQ--GKPRPELTWKKDGAEID-KNQINIRNSETDTIIFI 898
P + Q + + E N++ + G+P PE+ W K+ I + ++I S + I
Sbjct: 26637 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEI 26696
Query: 899 RKAERSHSGKYDLQVKVDKFVETASIDIQIIDR-PGPPQIVKIEDVWGENVALTWTPPKD 957
R A S SGKY ++ K + +A+ + ++ P + V + ++ +++
Sbjct: 26697 RNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFSSQSV 26756
Query: 958 DGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDA 1017
+A+ + S T ++ ++ +++ + E + + S + G+S
Sbjct: 26757 QMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSM---QESFVEMSSSSFMGISNMT 26813
Query: 1018 TMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI-AGYNATLNCSVRGNPKP 1076
+ ++ + + G P + L + +I G T+ C+ G P P
Sbjct: 26814 QLESSTSKMLKAG------------IRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTP 26861
Query: 1077 KITWM--KNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKL 1134
++TW K+ + R+ + + + TL I DGG Y N+ G+ +
Sbjct: 26862 EVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNI 26921
Query: 1135 EVKVI 1139
++ I
Sbjct: 26922 HIRSI 26926
Score = 48.9 bits (115), Expect = 3e-05
Identities = 59/283 (20%), Positives = 97/283 (34%), Gaps = 70/283 (24%)
Query: 854 GEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQV 913
GE+V L G P P +TW ++ +I+
Sbjct: 911 GESVTLECHISGYPSPTVTWYREDYQIE-------------------------------- 938
Query: 914 KVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADK 973
+SID QI + G +++ E ++ T + + G + + Y +
Sbjct: 939 --------SSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ--- 987
Query: 974 KSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIY 1033
V E + + + +TE E + F E+ + D ++T+E A Y
Sbjct: 988 -------VSEEFEKETTAVTEKFTTEE---KRFVESRDVVMTDTSLTEEQAGPGEPAAPY 1037
Query: 1034 KNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRY 1093
T+P+V + G + C V GNPKP + W K+ V + RY
Sbjct: 1038 --------------FITKPVVQKL-VEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRY 1082
Query: 1094 RMFSNQ--GVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKL 1134
++ N+ G C L I D G Y N G L
Sbjct: 1083 KVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125
Score = 48.9 bits (115), Expect = 3e-05
Identities = 81/404 (20%), Positives = 150/404 (37%), Gaps = 60/404 (14%)
Query: 266 KGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVT 325
+G RF ++ L+V WY ++I+PS + L I D+ Y
Sbjct: 3312 EGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFV 3371
Query: 326 AGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGP 385
A + V + LE + ER+E E E+ + + + EE +
Sbjct: 3372 ASNA-------VGQVSSTANLSLEAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSA 3424
Query: 386 KSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVN 445
+ + ++ +L +E V T S + + + + +++ ++
Sbjct: 3425 ELQLS-KINETLELL----------SESPVYPTKFDSEKEGTGPI----FIKEVSNADIS 3469
Query: 446 LGKEICLKCEISENIPG---KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV 502
+G L + IP +W NG+ + S K V G H L+I EDEG+Y
Sbjct: 3470 MGDVATLSVTVI-GIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYT 3528
Query: 503 -FAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRL---------------- 545
A + Y T+ + I+ +G T + +A + +L
Sbjct: 3529 CMASNDYGKTICSAYLKINSKG---EGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIR 3585
Query: 546 ---------EIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGV 596
E + GEP P W + +K + + S T +++ +R+DSG+
Sbjct: 3586 CAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGL 3645
Query: 597 YHINLKNEAGEAHASIKVKVV----DFPDPPV-APTVTEVGDDW 635
Y +N GE+ + ++ V+ D D P A + E +D+
Sbjct: 3646 YICKAENMLGESTCAAELLVLLEDTDMTDTPCKAKSTPEAPEDF 3689
Score = 48.9 bits (115), Expect = 3e-05
Identities = 86/372 (23%), Positives = 145/372 (38%), Gaps = 68/372 (18%)
Query: 784 VANKDLIDKTKFTITGLPTDAKIFVRV---KAVNAAGASE-PKYYSQPILVKEIIEPPKI 839
V +DL+ K ++G+P + ++ +++ +A+ AA ASE P +S+ + E +E +
Sbjct: 4009 VQGRDLLSKESL-LSGIPEEQRLNLKIQICRALQAAVASEQPGLFSEWLRNIEKVEVEAV 4067
Query: 840 RI---PRHLKQTYI----RRVGEAVNLVIPFQGKPRPELTWKKDGA--EIDKNQINIRNS 890
I PRH+ Y+ + V E V ++I L + A I +I+I +
Sbjct: 4068 NITQEPRHIMCMYLVTSAKSVTEEVTIIIEDVDPQMANLKMELRDALCAIIYEEIDILTA 4127
Query: 891 ETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVA- 949
E I K LQ ++D F + ++ ++ E+V NV
Sbjct: 4128 EGPRI--------QQGAKTSLQEEMDSFSGSQKVEPITEPEVESKYLISTEEVSYFNVQS 4179
Query: 950 ----LTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRV 1005
L TP +A+ +D+K E E +S+
Sbjct: 4180 RVKYLDATPVTKGVASAVV------SDEKQDESLKPSEEKEESSSE-------------- 4219
Query: 1006 FSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNAT 1065
G E AT+ + A +G + K + PM PLV+T + G
Sbjct: 4220 -----SGTEEVATVKIQEA----EGGLIKE---------DGPMIHTPLVDTVSEEGDIVH 4261
Query: 1066 LNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDG-GTYCCKAVND 1124
L S+ N K ++ W + D +++ +Q TL I K + D G Y C+A+ND
Sbjct: 4262 LTTSIT-NAK-EVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALND 4319
Query: 1125 LGTVEIECKLEV 1136
G KL V
Sbjct: 4320 SGKTATSAKLTV 4331
Score = 48.1 bits (113), Expect = 5e-05
Identities = 51/213 (23%), Positives = 86/213 (40%), Gaps = 21/213 (9%)
Query: 932 PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSAT 991
P P+ + + + L W P+ +G + I GY I+K ++ V + T++
Sbjct: 8798 PTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSF 8857
Query: 992 ITELVIGNEYY-FRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFT 1050
+ E + ++ Y FRV + N G SE + V+ +D ++ +
Sbjct: 8858 LVENLDEHQMYEFRVKAVNEIGESEPSLPLN---VVIQDDEVPPT----------IKLRL 8904
Query: 1051 QPLVNTYAI-AGYNATLNCSVRGNPKPKITWMKNKVAI------VDDPRYRMFSNQGVCT 1103
+T + AG + V G P PKI W KN+ I + + + ++
Sbjct: 8905 SVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTE 8964
Query: 1104 LEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
L I K D GTY A N LG+V +EV
Sbjct: 8965 LSIPKAVREDKGTYTVTASNRLGSVFRNVHVEV 8997
Score = 47.4 bits (111), Expect = 8e-05
Identities = 28/96 (29%), Positives = 44/96 (45%), Gaps = 2/96 (2%)
Query: 1044 SEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDD--PRYRMFSNQGV 1101
++AP FTQPL + + G AT + G P P+++W ++ I P ++ + G
Sbjct: 3 TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGR 62
Query: 1102 CTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1137
L I + + G Y KA N G +L VK
Sbjct: 63 AKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98
Score = 46.6 bits (109), Expect = 1e-04
Identities = 36/105 (34%), Positives = 48/105 (45%), Gaps = 4/105 (3%)
Query: 512 LPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSG 571
+PA V + P ++ GL VTVI G + LE ISG P P W R D I E S
Sbjct: 886 VPAPVEIPVTPPTLVSGL---KNVTVIEGESVTLECHISGYPSPTVTWYREDYQI-ESSI 941
Query: 572 RIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKV 616
+ + L+I A +DSG + + NEAG S + V
Sbjct: 942 DFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 986
Score = 46.6 bits (109), Expect = 1e-04
Identities = 29/93 (31%), Positives = 42/93 (45%), Gaps = 3/93 (3%)
Query: 1047 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIV---DDPRYRMFSNQGVCT 1103
P FT PL N A G N ++ +P+P +TW K+ I +D +Y S++G+
Sbjct: 25193 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQ 25252
Query: 1104 LEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
L I + D Y A N G + KL V
Sbjct: 25253 LTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25285
Score = 46.2 bits (108), Expect = 2e-04
Identities = 34/107 (31%), Positives = 47/107 (43%), Gaps = 4/107 (3%)
Query: 1034 KNPVYEDFDFSE----APMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVD 1089
++PVY SE P+F + + N G ATL+ +V G PKPKI W N V +
Sbjct: 3440 ESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTP 3499
Query: 1090 DPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
Y+ + +L I D G Y C A ND G L++
Sbjct: 3500 SADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKI 3546
Score = 46.2 bits (108), Expect = 2e-04
Identities = 25/93 (26%), Positives = 42/93 (45%)
Query: 1046 APMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLE 1105
AP+ + + G+ A C ++ P + W K I + + + S++ + +LE
Sbjct: 4336 APVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLE 4395
Query: 1106 IRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1138
I + D G Y CKA N+ G+V L V V
Sbjct: 4396 ILRTQVVDCGEYTCKASNEYGSVSCTATLTVTV 4428
Score = 45.8 bits (107), Expect = 2e-04
Identities = 30/96 (31%), Positives = 39/96 (40%), Gaps = 3/96 (3%)
Query: 1047 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSN-QGVCTLE 1105
P F + L G A +V G P P +TW K + Y + N G T
Sbjct: 3575 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3634
Query: 1106 IRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVIAQ 1141
+ P D G Y CKA N LG E C E+ V+ +
Sbjct: 3635 VNDPQREDSGLYICKAENMLG--ESTCAAELLVLLE 3668
Score = 45.8 bits (107), Expect = 2e-04
Identities = 29/100 (29%), Positives = 49/100 (49%), Gaps = 5/100 (5%)
Query: 932 PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEH--YHRTS 989
P P + +V ++ +TW P D G IT Y ++K + S W V + + T
Sbjct: 10515 PDAPDQPIVTEVTKDSALVTWNKPHDGGKP-ITNYILEKRETMSKRWARVTKDPIHPYTK 10573
Query: 990 ATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARD 1029
+ +L+ G +Y FRV +EN G+ + + +K V A+D
Sbjct: 10574 FRVPDLLEGCQYEFRVSAENEIGIGDPSPPSK--PVFAKD 10611
Score = 44.7 bits (104), Expect = 5e-04
Identities = 62/284 (21%), Positives = 105/284 (36%), Gaps = 51/284 (17%)
Query: 869 PELT--WKKDGAEID-KNQINIRNSETDTIIFIRKAERSHSGKYDL----QVKVDK-FVE 920
P++T W KD E+ ++I I+ + + I S +GKY + V K FVE
Sbjct: 3038 PDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVE 3097
Query: 921 TASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNA------AITGYTIQKADKK 974
+ I+ I + +++ + + + + +DD +A + +Q+ K
Sbjct: 3098 GRDVRIRSIKK-------EVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHK- 3149
Query: 975 SMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYK 1034
+ V HR + T EY F V N ++ +Y
Sbjct: 3150 ----YVVERRIHRMFISETRQSDAGEYTF-VAGRNRSSVT-----------------LYV 3187
Query: 1035 NPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYR 1094
N E P Q L +G A + G P+PKI+W K + + + +
Sbjct: 3188 NA-------PEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCK 3240
Query: 1095 MFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1138
+ TL + + P D Y C+A ND G L V+V
Sbjct: 3241 FLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEV 3284
Score = 44.3 bits (103), Expect = 7e-04
Identities = 29/98 (29%), Positives = 51/98 (52%), Gaps = 1/98 (1%)
Query: 534 TVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDD 593
++TV G+++RL++ ++G P P + R D A ++ S + D +L+I A +D
Sbjct: 112 SMTVRQGSQVRLQVRVTGIPTPVVKFYR-DGAEIQSSLDFQISQEGDLYSLLIAEAYPED 170
Query: 594 SGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEV 631
SG Y +N N G A ++ ++ V + P T T V
Sbjct: 171 SGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIV 208
Score = 44.3 bits (103), Expect = 7e-04
Identities = 64/320 (20%), Positives = 110/320 (34%), Gaps = 40/320 (12%)
Query: 315 QMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEV-SEDDANVK 373
Q T + +Y E S + F + +T ++ CG+ V S+ A VK
Sbjct: 25856 QKTSERKY------EVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVK 25909
Query: 374 WFKNGEEIIPGPKSRYRIRVEGKKHILIIEGAT-------------KADAAEYSVM-TTG 419
W+ NG E+ K Y G + I++ T K +A++Y+ + TG
Sbjct: 25910 WYHNGVELQESSKIHYT-NTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTG 25968
Query: 420 GQSSAKLSV---DLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDR 476
G + S + P + LT E+ + + K+ +
Sbjct: 25969 GDYTTYASQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESL 26028
Query: 477 LKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVT 536
H + + AL E + TL A++ L ++T
Sbjct: 26029 SSYEHSASAE--MKSAALEEKSLEEKSTTRKIKTTLAARI------------LTKPRSMT 26074
Query: 537 VIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGV 596
V G R GEP P W R + ++ S R + + ST I + D G
Sbjct: 26075 VYEGESARFSCDTDGEPVPTVTWLRKGQ-VLSTSARHQVTTTKYKSTFEISSVQASDEGN 26133
Query: 597 YHINLKNEAGEAHASIKVKV 616
Y + ++N G+ A + +
Sbjct: 26134 YSVVVENSEGKQEAEFTLTI 26153
Score = 43.9 bits (102), Expect = 9e-04
Identities = 94/440 (21%), Positives = 160/440 (36%), Gaps = 71/440 (16%)
Query: 246 REEKKSAAFAKILDPAYQVDKGGRVRFVVELAD-PKLEVKWYKNGQEIRPSTKYIFEHKG 304
++EK+ +P +V +G RF + P+ +V WY NGQ IR S ++ + G
Sbjct: 1789 QKEKQKPDIVLYPEPV-RVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDG 1847
Query: 305 CQRILFINNCQMTDDSEYYVTAG------DEKCSTELFVREP------------------ 340
L I +C+ D E VTA + K E+ RE
Sbjct: 1848 I-HYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRPEFHVH 1906
Query: 341 --------------PIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGE-----EI 381
P+ T+ E ER+ E E + FK E
Sbjct: 1907 EPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEA 1966
Query: 382 IPGPKSRYRIRVEGKKHIL-------------IIEGATKADAAEYSV-MTTGGQSSAKLS 427
I + + R + E + +L + E KA A E + + T +LS
Sbjct: 1967 ITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELS 2026
Query: 428 VDLKPLKILTPLTDQTVNLGKEICLKCEI--SENIPGKWTKNGLPVQESDRLK-VVHKGR 484
++ KI + QTV G + + + + +W KNG+ ++ SDR+ +
Sbjct: 2027 PSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDN 2086
Query: 485 IHKLVIANALTEDEGDYVFAPDAYNVTLPAKVH---VIDPPKIILDGLDADNTVTVIAGN 541
+ +LVI + ED + A N+ H ++ ++I + + V
Sbjct: 2087 VCELVIRDVTAEDSASIMV--KAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDT 2144
Query: 542 KLRLEIPISGEPPPKAMWSRGDKAIMEGSG-RIRTE-SYPDSSTLVIDIAERDDSGVYHI 599
E S EP K W + + EG R+ ++ S L ID ++ +D +
Sbjct: 2145 MATFECETS-EPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLV 2203
Query: 600 NLKNEAGEAHASIKVKVVDF 619
+N A ++ VV+F
Sbjct: 2204 EDENVKTTAKLIVEGAVVEF 2223
Score = 43.9 bits (102), Expect = 9e-04
Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 1/79 (1%)
Query: 1059 IAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYC 1118
+ G A C V G P+PK+ W N I R+R+ G+ L+I YD G
Sbjct: 1807 LEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVK 1865
Query: 1119 CKAVNDLGTVEIECKLEVK 1137
A N G +E + KLE++
Sbjct: 1866 VTAENPEGVIEHKVKLEIQ 1884
Score = 43.9 bits (102), Expect = 9e-04
Identities = 59/286 (20%), Positives = 102/286 (35%), Gaps = 24/286 (8%)
Query: 854 GEAVNLVIPFQGKPRPELTWKKDGAEI-DKNQINIRNSETDTIIFIRKAERSHSGKYDLQ 912
G+ ++ Q KP E+ W +G E+ + ++I+ N+ + I SG Y +
Sbjct: 25891 GQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTY--R 25948
Query: 913 VKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKAD 972
+ AS D +D G E V + P A Y +
Sbjct: 25949 AVCTNYKGEAS-DYATLDVTGGDYTTYASQRRDEEVPRSVFPELTRTEA----YAVSSFK 26003
Query: 973 KKS-MEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGK 1031
K S ME + + + +TE E++ A+ +SA +
Sbjct: 26004 KTSEMEASSSVRE---VKSQMTET-----------RESLSSYEHSASAEMKSAALEEKSL 26049
Query: 1032 IYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDP 1091
K+ + A + T+P T G +A +C G P P +TW++ +
Sbjct: 26050 EEKSTTRKIKTTLAARILTKPRSMT-VYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSA 26108
Query: 1092 RYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1137
R+++ + + T EI D G Y N G E E L ++
Sbjct: 26109 RHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 26154
Score = 43.5 bits (101), Expect = 0.001
Identities = 61/263 (23%), Positives = 104/263 (39%), Gaps = 35/263 (13%)
Query: 261 AYQVDKGGRVRFVVEL-ADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDD 319
+++V G RF++ + + P EVKWY NG E++ S+K + + L I +C TDD
Sbjct: 25885 SHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCH-TDD 25943
Query: 320 SEYY------------------VTAGD-EKCSTELFVREPPIMVTKQLEDTTAYCGERVE 360
S Y VT GD +++ E P V +L T AY +
Sbjct: 25944 SGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPRSVFPELTRTEAYAVSSFK 26003
Query: 361 LECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGG 420
E+ E ++V+ K+ + R + +H + + +A +
Sbjct: 26004 KTSEM-EASSSVREVKS-------QMTETRESLSSYEH----SASAEMKSAALEEKSLEE 26051
Query: 421 QSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEI-SENIPG-KWTKNGLPVQESDRLK 478
+S+ + +ILT TV G+ C+ E +P W + G + S R +
Sbjct: 26052 KSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQ 26111
Query: 479 VVHKGRIHKLVIANALTEDEGDY 501
V I++ DEG+Y
Sbjct: 26112 VTTTKYKSTFEISSVQASDEGNY 26134
Score = 43.1 bits (100), Expect = 0.001
Identities = 41/170 (24%), Positives = 67/170 (39%), Gaps = 16/170 (9%)
Query: 464 WTKNGLPVQESDRLKVVHK-GRIHKLVIANALTEDEGDYVFAPD--------AYNVTLPA 514
W +G + KVV K L+I A D G++ + +T+ A
Sbjct: 1444 WFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEA 1503
Query: 515 KVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGS-GRI 573
H + P + + V + G++L +++ +G P P +W + I+ +I
Sbjct: 1504 VEHQVKPMFV-----EKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKI 1558
Query: 574 RTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKV-VDFPDP 622
R E + L ID DS Y N+AG KV V V+F +P
Sbjct: 1559 RIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEP 1608
Score = 43.1 bits (100), Expect = 0.001
Identities = 67/327 (20%), Positives = 116/327 (35%), Gaps = 65/327 (19%)
Query: 344 VTKQLEDTTAYCGERVELECEVSEDDAN--VKWFKNGEEIIPGPKSRYRIRVEGKKHILI 401
V+ Q+ G V+ C++ D + V W+ ++ K Y I E IL
Sbjct: 25073 VSGQIMHAVGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEK--YEITYEDGVAILY 25130
Query: 402 IEGATKADAAEY--SVMTTGGQSSAKLSVDLK---------------------------- 431
++ TK D Y V+ G+ S+ + +K
Sbjct: 25131 VKDITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLE 25190
Query: 432 -PLKILTPLTDQTVNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVV----HKGR 484
P + PL ++T +G+ + I+ + W K+G ++ D K KG
Sbjct: 25191 RPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKG- 25249
Query: 485 IHKLVIANALTEDEGDYV------FAPDAYNVTLPAKVHVIDPP---------KIILDGL 529
+++L I + T+D+ +Y + D+ L +H PP K +L
Sbjct: 25250 LYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLH--PPPTDSTLRPMFKRLLANA 25307
Query: 530 DADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIA 589
+ G + EI +SG PPP W + + + G D L I
Sbjct: 25308 ECQE------GQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDT 25361
Query: 590 ERDDSGVYHINLKNEAGEAHASIKVKV 616
+D+G Y + N AG ++V
Sbjct: 25362 LPEDTGYYRVTATNTAGSTSCQAHLQV 25388
Score = 42.7 bits (99), Expect = 0.002
Identities = 33/111 (29%), Positives = 46/111 (41%), Gaps = 5/111 (4%)
Query: 1021 KESAVIARDGKI----YKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKP 1076
+E +A +GKI +K E EAP + + + G +A V G P P
Sbjct: 2002 EEKKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDP 2061
Query: 1077 KITWMKNKVAIVDDPR-YRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLG 1126
+ W KN V I R Y + VC L IR + D + KA+N G
Sbjct: 2062 ECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAG 2112
Score = 41.2 bits (95), Expect = 0.006
Identities = 31/101 (30%), Positives = 45/101 (44%), Gaps = 7/101 (6%)
Query: 1022 ESAVIARDGKIYKNPVYEDFDFSEAPM-FTQPLVNTYAIAGYNATLNCSVRGNPKPKITW 1080
E + A+D K + N + E P+ FT+PL + G A L C V K+ W
Sbjct: 5767 EVQLTAKDFKTHANLFVK-----EPPVEFTKPLEDQTVEEGATAVLECEV-SRENAKVKW 5820
Query: 1081 MKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKA 1121
KN I+ +Y + ++ V L I +P D TY C A
Sbjct: 5821 FKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDA 5861
Score = 40.4 bits (93), Expect = 0.010
Identities = 73/318 (22%), Positives = 115/318 (36%), Gaps = 33/318 (10%)
Query: 831 KEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQ-GKPRPELTWKKDGAEIDKNQINIRN 889
K +E +RI K+ +V E V+ F+ + + W KDG EI+
Sbjct: 3093 KLFVEGRDVRIRSIKKEV---QVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHK 3149
Query: 890 SETDTII---FIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGE 946
+ I FI + +S +G+Y ++ T ++ P PPQ+++ E
Sbjct: 3150 YVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTL-----YVNAPEPPQVLQ------E 3198
Query: 947 NVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEY---YF 1003
+T K A+ I + + W+ E T L G EY
Sbjct: 3199 LQPVTVQSGKPARFCAV----ISGRPQPKISWYKE-EQLLSTGFKCKFLHDGQEYTLLLI 3253
Query: 1004 RVFSENM----CGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI 1059
F E+ C D + SA ++ + +P E + P PL +T
Sbjct: 3254 EAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYP--PAIITPLQDTVTS 3311
Query: 1060 AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCC 1119
G A C V G K++W I +RM + LEI + P D GTY
Sbjct: 3312 EGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTF 3370
Query: 1120 KAVNDLGTVEIECKLEVK 1137
A N +G V L ++
Sbjct: 3371 VASNAVGQVSSTANLSLE 3388
Score = 40.0 bits (92), Expect = 0.013
Identities = 44/211 (20%), Positives = 95/211 (45%), Gaps = 28/211 (13%)
Query: 245 RREEKKSAAFAKILDPAYQVD-------KGGRVRFVVELAD-PKLEVKWYKNGQEIRP-- 294
R EE + ++ P + + +G RF +++ P E W+ +GQ+I
Sbjct: 1396 RLEETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDY 1455
Query: 295 STKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFV--------REPPIMVTK 346
+ K + + G Q ++ + +D E+ V A + + + V + M +
Sbjct: 1456 THKVVIKEDGTQSLIIVP-ATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVE 1514
Query: 347 QLEDTTAYCGERVELECEVSED-DANVKWFKNGEEIIPGPKSRY-RIRVEGKK--HILII 402
+L++ G R+E++ + + + ++ W KN + I+P +Y +IR+EG K L I
Sbjct: 1515 KLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVP---HKYPKIRIEGTKGEAALKI 1571
Query: 403 EGATKADAAEY--SVMTTGGQSSAKLSVDLK 431
+ D+A Y + + G+ + + V+++
Sbjct: 1572 DSTVSQDSAWYTATAINKAGRDTTRCKVNVE 1602
Score = 40.0 bits (92), Expect = 0.013
Identities = 96/465 (20%), Positives = 165/465 (35%), Gaps = 92/465 (19%)
Query: 20 EEPSKEKEAGTTPAKDWTLVETPPGEEQAKQNANSQLSILFIEKPQGGTVKVGEDITFIA 79
E S + + + K L E E+ + + L+ + KP+ TV GE F
Sbjct: 26026 ESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSC 26085
Query: 80 KVKAEDLLRKPTIKWF-KGKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAG 138
E + PT+ W KG+ + S + +H ++ TFE+ ++A D G
Sbjct: 26086 DTDGEPV---PTVTWLRKGQ---VLSTSARHQVTTTKYKS-----TFEISSVQASDE--G 26132
Query: 139 NYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRRE 198
NY V + F L + ++ T + K S E + + E + +
Sbjct: 26133 NYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVK-SPEPRVKSPE----AVKSPKR 26187
Query: 199 VKQQEEEPQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKIL 258
VK E V KP+ EK+ + K + ++ E K A
Sbjct: 26188 VKSPEPSHPKAVSP--TETKPTPTEKVQH----LPVSAPPKITQFLKAEASKEIA----- 26236
Query: 259 DPAYQVDKGGRVRFVVELADPKL-EVKWYKNGQEIRPSTKYIFEHKGCQRI-LFINNCQM 316
++ VVE + + EV WYK+G++++ + + F + L INN
Sbjct: 26237 ----------KLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTE 26286
Query: 317 TDDSEYY---------------------------------VTAGDEKCSTELFVR--EP- 340
+D EY D+K + R EP
Sbjct: 26287 SDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPK 26346
Query: 341 --------PIMVTKQLEDTTAYCGERVELECEVS-EDDANVKWFKNGEEIIPGPKSRYRI 391
P++VT L+DTT + + + E W K+G+ I G K Y++
Sbjct: 26347 APEPISSKPVIVT-GLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGK--YKL 26403
Query: 392 RVEGKKHILIIEGATKADAAEY--SVMTTGGQSSAKLSVDLKPLK 434
+ L I +D+ Y +V + G S+ + +K +K
Sbjct: 26404 SEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIK 26448
Score = 39.7 bits (91), Expect = 0.017
Identities = 25/98 (25%), Positives = 37/98 (37%)
Query: 1039 EDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSN 1098
+ F AP T + + G N +V+ P ++ W N V + + + +
Sbjct: 25869 QPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNT 25928
Query: 1099 QGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
GV TLEI D GTY N G L+V
Sbjct: 25929 SGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDV 25966
Score = 39.3 bits (90), Expect = 0.022
Identities = 58/327 (17%), Positives = 107/327 (32%), Gaps = 45/327 (13%)
Query: 854 GEAVNLVIPFQGKPRPELTWKKDGAEIDKN---QINIRNSETDTIIFIRKAERSHSGKYD 910
G+ + G+P PE W DG +I + ++ I+ T ++I + A S SG++
Sbjct: 1425 GQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIV-PATPSDSGEWT 1483
Query: 911 L--QVKVDKFVETASIDIQIIDRPGPPQIV----------------KIEDVWGENVALTW 952
+ Q + + + + ++ ++ P V K+ N + W
Sbjct: 1484 VVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVW 1543
Query: 953 TPPKD------------DGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNE 1000
D +G I + W+T ++ T + E
Sbjct: 1544 LKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATA-INKAGRDTTRCKVNVE 1602
Query: 1001 YYFR--------VFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQP 1052
F + E A E + + ++ D + + P F +
Sbjct: 1603 VEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKK 1662
Query: 1053 LVNTYAIAGYNATLNCSVR--GNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPS 1110
L + A C + G+P + W+ + + R RM + G C+L+
Sbjct: 1663 LTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAY 1722
Query: 1111 PYDGGTYCCKAVNDLGTVEIECKLEVK 1137
D G C+A N GT L VK
Sbjct: 1723 SRDSGIITCRATNKYGTDHTSATLIVK 1749
Score = 38.9 bits (89), Expect = 0.028
Identities = 44/162 (27%), Positives = 69/162 (42%), Gaps = 13/162 (8%)
Query: 279 PKLEVKWYKNGQEIRPST--KYIFEHKGCQRILFINNCQMTDDSEYYVTA----GDEKCS 332
P EV W+++GQ I ST + L I + Y + A G +
Sbjct: 33 PVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKATNGSGQATST 92
Query: 333 TELFVR---EPPIMVTKQLEDTTAYCGERVELECEVSE-DDANVKWFKNGEEIIPGPKSR 388
EL V+ PP V ++L+ T G +V L+ V+ VK++++G EI
Sbjct: 93 AELLVKAETAPPNFV-QRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEI--QSSLD 149
Query: 389 YRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDL 430
++I EG + L+I A D+ YSV T A + +L
Sbjct: 150 FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAEL 191
Score = 38.5 bits (88), Expect = 0.037
Identities = 75/342 (21%), Positives = 130/342 (38%), Gaps = 50/342 (14%)
Query: 316 MTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDA-NVKW 374
MTD S AG + + F+ +P +V K +E G V C+V + +V W
Sbjct: 1018 MTDTSLTEEQAGPGEPAAPYFITKP--VVQKLVE------GGSVVFGCQVGGNPKPHVYW 1069
Query: 375 FKNGEEIIPGPKSRYRIRVEGKKHI----LIIEGATKADAAEYSVMTTG--GQSSAKLSV 428
K+G + G YR +V K L+I DA EY+++ G++SA S+
Sbjct: 1070 KKSGVPLTTG----YRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125
Query: 429 DLKPLKILTPLTDQTVNLGKEICL---KCEISENIPGKWTKNGLPVQESDRLKVVHKGRI 485
+ L + Q + ++ + ++ E PG + + + ++ K
Sbjct: 1126 LEEADYELLMKSQQEMLYQTQVTAFVQEPKVGETAPG-FVYSEYEKEYEKEQALIRKKMA 1184
Query: 486 HKLVIANALTEDEGDYVFAPDA----------YNVTLPAKVHVIDPPKIILD-------- 527
V+ ED+ ++ + + TL + K+ +D
Sbjct: 1185 KDTVVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVE 1244
Query: 528 -GLDAD-NTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS-STL 584
G D+ ++ G + +SG P PK W + K I G R + + D ++L
Sbjct: 1245 SGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGE-RYQMDFLQDGRASL 1303
Query: 585 VIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAP 626
I + +D G+Y N G A S K+ V P AP
Sbjct: 1304 RIPVVLPEDEGIYTAFASNIKGNAICSGKLYV-----EPAAP 1340
Score = 38.1 bits (87), Expect = 0.048
Identities = 38/173 (21%), Positives = 68/173 (39%), Gaps = 11/173 (6%)
Query: 337 VREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGK 396
++E M+ L DT + G+ V L ++ +F+N +++P + +++ +
Sbjct: 4238 IKEDGPMIHTPLVDTVSEEGDIVHLTTSITNAKEVNWYFEN--KLVPSDE-KFKCLQDQN 4294
Query: 397 KHILIIEGATKAD-AAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVN-----LGKEI 450
+ L+I+ D EY S L +K P+ + + LG
Sbjct: 4295 TYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLA 4354
Query: 451 CLKCEISE--NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 501
CEI N+ +W K G + ESD+ + I L I D G+Y
Sbjct: 4355 KFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEY 4407
Score = 38.1 bits (87), Expect = 0.048
Identities = 27/98 (27%), Positives = 41/98 (41%), Gaps = 3/98 (3%)
Query: 1042 DFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGV 1101
D + PMF + L N G + V G P P + W K+ + P + ++G+
Sbjct: 25293 DSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEII-HEGL 25351
Query: 1102 --CTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1137
L IR P D G Y A N G+ + L+V+
Sbjct: 25352 DYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 25389
Score = 37.7 bits (86), Expect = 0.063
Identities = 26/83 (31%), Positives = 34/83 (40%), Gaps = 5/83 (6%)
Query: 264 VDKGGRVRFVVELAD-PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 322
V G VRF + P KW +G EI+ Y E +L I NC D EY
Sbjct: 11025 VKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEY 11084
Query: 323 YVT----AGDEKCSTELFVREPP 341
+T AG + + L V + P
Sbjct: 11085 QITVSNAAGSKTVAVHLTVLDVP 11107
Score = 37.7 bits (86), Expect = 0.063
Identities = 19/65 (29%), Positives = 31/65 (47%)
Query: 1077 KITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
++TW + + +Y + GV L ++ + D GTY CK VND G +L V
Sbjct: 25102 QVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFV 25161
Query: 1137 KVIAQ 1141
K + +
Sbjct: 25162 KGVRE 25166
Score = 37.0 bits (84), Expect = 0.11
Identities = 25/94 (26%), Positives = 40/94 (42%), Gaps = 1/94 (1%)
Query: 1047 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYR-MFSNQGVCTLE 1105
P+F V+ + G A + V G P P+ W + IV+D ++ + G +L
Sbjct: 1411 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLI 1470
Query: 1106 IRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVI 1139
I +P D G + A N G I L V+ +
Sbjct: 1471 IVPATPSDSGEWTVVAQNRAGRSSISVILTVEAV 1504
Score = 36.6 bits (83), Expect = 0.14
Identities = 53/275 (19%), Positives = 95/275 (34%), Gaps = 51/275 (18%)
Query: 340 PPIMVTKQLEDTTAYCGERVELECEVSE-DDANVKWFKNGEEIIPGPKSRYRIRVEGKKH 398
PP +V+ L++ T GE V LEC +S V W++ +I ++I +
Sbjct: 896 PPTLVSG-LKNVTVIEGESVTLECHISGYPSPTVTWYREDYQI--ESSIDFQITFQSGIA 952
Query: 399 ILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISE 458
L+I A D+ + T VN + C ++
Sbjct: 953 RLMIREAFAEDSGRF--------------------------TCSAVNEAGTVSTSCYLAV 986
Query: 459 NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIAN-ALTEDEGDYVFAPDAYNVTLPAKVH 517
+ ++ K V E + +V+ + +LTE++ Y +T P
Sbjct: 987 QVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQK 1046
Query: 518 VIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSG-RIRTE 576
+++ G + + G P P W + + G ++
Sbjct: 1047 LVE-------------------GGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYN 1087
Query: 577 SYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHAS 611
LVI + DD+G Y I ++N+ GE AS
Sbjct: 1088 KQTGECKLVISMTFADDAGEYTIVVRNKHGETSAS 1122
Score = 36.2 bits (82), Expect = 0.18
Identities = 45/250 (18%), Positives = 92/250 (36%), Gaps = 31/250 (12%)
Query: 873 WKKDGAEIDKN-QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDR 931
W KDG EI + + +I+ I+ I+KA+ G+Y DK +++ ++I
Sbjct: 5197 WFKDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKV 5256
Query: 932 PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSAT 991
P V++ + + + P G + G + T++
Sbjct: 5257 EKPLYGVEVFVGETAHFEIELSEPDVHGQWKLKGQPL-------------------TASP 5297
Query: 992 ITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQ 1051
E++ + + + G++ + + +A A + K+ + P+ +F
Sbjct: 5298 DCEIIEDGKKHILILHNCQLGMTGEVSFQAANAKSAANLKVKELPL----------IFIT 5347
Query: 1052 PLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSP 1111
PL + A C V PK W+K I D R+ + + ++ I+ +
Sbjct: 5348 PLSDVKVFEKDEAKFECEVSREPK-TFRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAF 5406
Query: 1112 YDGGTYCCKA 1121
D Y +A
Sbjct: 5407 EDEAKYMFEA 5416
Score = 36.2 bits (82), Expect = 0.18
Identities = 39/146 (26%), Positives = 56/146 (38%), Gaps = 11/146 (7%)
Query: 276 LADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTEL 335
L PK V W K Q ++ + + FE IL IN C +D Y +TA +
Sbjct: 14593 LGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARN------- 14645
Query: 336 FVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEG 395
V E ++T Q+ D ++ + EVS D W E P S Y + +
Sbjct: 14646 IVGEVGDVITIQVHDIPGPPTGPIKFD-EVSSDFVTFSW-DPPENDGGVPISNYVVEMRQ 14703
Query: 396 KKHILIIEGATKADAAEYSV--MTTG 419
+E AT Y +TTG
Sbjct: 14704 TDSTTWVELATTVIRTTYKATRLTTG 14729
Score = 35.8 bits (81), Expect = 0.24
Identities = 25/91 (27%), Positives = 42/91 (46%), Gaps = 1/91 (1%)
Query: 534 TVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS-STLVIDIAERD 592
+V V+ G+ E ISG P P+ W R + I + S+ D + L I +
Sbjct: 14 SVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKA 73
Query: 593 DSGVYHINLKNEAGEAHASIKVKVVDFPDPP 623
+SG Y + N +G+A ++ ++ V PP
Sbjct: 74 NSGRYSLKATNGSGQATSTAELLVKAETAPP 104
Score = 35.8 bits (81), Expect = 0.24
Identities = 23/89 (25%), Positives = 34/89 (38%), Gaps = 2/89 (2%)
Query: 536 TVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSG--RIRTESYPDSSTLVIDIAERDD 593
T G +R + I+ P P W + + I G + ES L I+ DD
Sbjct: 25203 TAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDD 25262
Query: 594 SGVYHINLKNEAGEAHASIKVKVVDFPDP 622
Y + +N+ GE K+ V P P
Sbjct: 25263 DAEYTVVARNKYGEDSCKAKLTVTLHPPP 25291
Score = 35.0 bits (79), Expect = 0.41
Identities = 23/91 (25%), Positives = 37/91 (40%)
Query: 1047 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEI 1106
P F Q L + G L V G P P + + ++ I +++ + +L I
Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLI 163
Query: 1107 RKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1137
+ P D GTY A N +G +L V+
Sbjct: 164 AEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 35.0 bits (79), Expect = 0.41
Identities = 27/90 (30%), Positives = 39/90 (43%), Gaps = 4/90 (4%)
Query: 1047 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEI 1106
P FT L + A+ TL C V + K W K+ IV P+Y + ++ L+I
Sbjct: 5166 PYFTVKLHDKTAVEKDEITLKCEVSKDVPVK--WFKDGEEIVPSPKYSIKADGLRRILKI 5223
Query: 1107 RKPSPYDGGTYCCKAVND--LGTVEIECKL 1134
+K D G Y C D V +E +L
Sbjct: 5224 KKADLKDKGEYVCDCGTDKTKANVTVEARL 5253
Score = 33.9 bits (76), Expect = 0.91
Identities = 27/119 (22%), Positives = 51/119 (42%), Gaps = 11/119 (9%)
Query: 393 VEGKKHILIIEGATKADAAEYSVM-------TTGGQSSAKLSVDLKPLKILTPLTDQTVN 445
VE KK + + T + V+ T + A + + + P +++ L + TV
Sbjct: 850 VEVKKEVGVSITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVI 909
Query: 446 LGKEICLKCEISENIPGK---WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 501
G+ + L+C IS P W + ++ S ++ + I +L+I A ED G +
Sbjct: 910 EGESVTLECHIS-GYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRF 967
Score = 33.5 bits (75), Expect = 1.2
Identities = 35/140 (25%), Positives = 63/140 (45%), Gaps = 11/140 (7%)
Query: 792 KTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIR 851
+ K TI + +KA N +G + + +LVK PP + L+ +R
Sbjct: 62 RAKLTIPAVTKANSGRYSLKATNGSGQATS---TAELLVKAETAPPNF--VQRLQSMTVR 116
Query: 852 RVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTI--IFIRKAERSHSGKY 909
+ G V L + G P P + + +DGAEI ++ ++ + S+ + + I +A SG Y
Sbjct: 117 Q-GSQVRLQVRVTGIPTPVVKFYRDGAEI-QSSLDFQISQEGDLYSLLIAEAYPEDSGTY 174
Query: 910 DLQV--KVDKFVETASIDIQ 927
+ V + TA + +Q
Sbjct: 175 SVNATNSVGRATSTAELLVQ 194
Score = 33.5 bits (75), Expect = 1.2
Identities = 105/543 (19%), Positives = 203/543 (37%), Gaps = 71/543 (13%)
Query: 3 EPTKKEENEVP-APAPPPEEPSKEKEAGTTPAKDWTLVETPPGEEQAKQNANSQLSILFI 61
+P K EE P P PPE PS E +L + P K + S+++ +I
Sbjct: 23815 KPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRP-----KDDGGSRVTGYYI 23869
Query: 62 EKPQGGTVK-VGEDITFIAKVKAEDLLRKPTIKWF------KGKWMDLASKAGKHLQLKE 114
E+ + T K V + T I P ++ + S A + + K+
Sbjct: 23870 ERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKD 23929
Query: 115 TFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSA 174
F++ S+ E+ I DS + E E G +
Sbjct: 23930 PFDKPSQPGELEILSISK------------------DSVTLQWEKPECDGGKEILGYWVE 23971
Query: 175 FKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLKNAKPSEYEKIAF---QYGI 231
+++SG+ ++ K++ ++ Q + LL+ +EYE F + G+
Sbjct: 23972 YRQSGDSAW------------KKSNKERIKDKQFTIGGLLE---ATEYEFRVFAENETGL 24016
Query: 232 TDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQE 291
+ R +K + ++ D ++ + ++ + + P ++KWY+ G+E
Sbjct: 24017 SRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQI-VGRPLPDIKWYRFGKE 24075
Query: 292 IRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTA----GDEKCSTELFVREPPIMVT-- 345
+ S KY G L + + D+ Y A G+ + S++L ++ P
Sbjct: 24076 LIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGY 24135
Query: 346 KQLEDTTAYCGERVELE-CEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEG 404
E G + L + + WF +G++++ ++ E H+++
Sbjct: 24136 PLKEKYYGAVGSTLRLHVMYIGRPVPAMTWF-HGQKLLQNSENITIENTEHYTHLVMKNV 24194
Query: 405 ATKADAAEYSVMTTG--GQSSAKLSVDL--KPLKILTPLTDQTVNLGKEICLKCEISENI 460
K A +Y V + G A L V++ KP K P+ + + L + + +
Sbjct: 24195 QRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEAL-LKNSAVISWKPPADD 24253
Query: 461 PGKWTKNGL----PVQESDRLKVVHKG-RIHKLVIANALTEDEGDY--VFAPDAYNVTLP 513
G W N + +E ++V + I N LTE+ G Y V A + + ++ P
Sbjct: 24254 GGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVN-LTENAGYYFRVSAQNTFGISDP 24312
Query: 514 AKV 516
+V
Sbjct: 24313 LEV 24315
Score = 33.5 bits (75), Expect = 1.2
Identities = 43/147 (29%), Positives = 59/147 (40%), Gaps = 10/147 (6%)
Query: 279 PKLEVKWYKNGQE-IRPSTKY-IFEHKGCQRILFINNCQMTDDSEYYVTA----GDEKCS 332
PK VKWY+ G+E I KY I E KG L I + D + Y V A G +
Sbjct: 24458 PKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGT 24517
Query: 333 TELFVREP-PIMVTKQLED---TTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSR 388
L V P I + K LE A GE V ++ S V ++ G+++I
Sbjct: 24518 ASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHY 24577
Query: 389 YRIRVEGKKHILIIEGATKADAAEYSV 415
I ++ G + DA Y V
Sbjct: 24578 QVIVTRSFTSLVFPNGVERKDAGFYVV 24604
Score = 33.1 bits (74), Expect = 1.5
Identities = 21/96 (21%), Positives = 41/96 (42%), Gaps = 3/96 (3%)
Query: 847 QTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ---INIRNSETDTIIFIRKAER 903
Q+ + G G P PE++W +DG I + + I S+ + I +
Sbjct: 13 QSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTK 72
Query: 904 SHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVK 939
++SG+Y L+ T++ ++ + PP V+
Sbjct: 73 ANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQ 108
Score = 33.1 bits (74), Expect = 1.5
Identities = 21/93 (22%), Positives = 39/93 (41%), Gaps = 1/93 (1%)
Query: 538 IAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVY 597
+ G R ++ + G P P+ W + I+ + +L+I A DSG +
Sbjct: 1423 LEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEW 1482
Query: 598 HINLKNEAGEAHASIKVKVVDFPDPPVAPTVTE 630
+ +N AG + S+ + V+ + V P E
Sbjct: 1483 TVVAQNRAGRSSISV-ILTVEAVEHQVKPMFVE 1514
Score = 33.1 bits (74), Expect = 1.5
Identities = 19/61 (31%), Positives = 27/61 (44%), Gaps = 1/61 (1%)
Query: 1064 ATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVN 1123
AT C P K+ W K+ + + + +YRM S++ V L I D Y C V
Sbjct: 2146 ATFECET-SEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVE 2204
Query: 1124 D 1124
D
Sbjct: 2205 D 2205
Score = 32.3 bits (72), Expect = 2.6
Identities = 28/116 (24%), Positives = 51/116 (43%), Gaps = 8/116 (6%)
Query: 105 KAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTG 164
KAG+ + + S Y ++I++ + G Y C+ + + SC+ L V
Sbjct: 4372 KAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV----- 4426
Query: 165 TTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLKNAKPS 220
T P + + E E+ +L++R +EEEP+V+ +L K KP+
Sbjct: 4427 TVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKR---PEEEEPKVEPKKLEKVKKPA 4479
Score = 32.3 bits (72), Expect = 2.6
Identities = 27/117 (23%), Positives = 42/117 (35%), Gaps = 9/117 (7%)
Query: 1004 RVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYN 1063
R+ N C L ++A + E G + E +FT+ L N
Sbjct: 5931 RILVINKCLLDDEAEYSCEVRTARTSGMLTV--------LEEEAVFTKNLANIEVSETDT 5982
Query: 1064 ATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCK 1120
L C V P ++ W K I++ RY + + L I+ D G Y C+
Sbjct: 5983 IKLVCEV-SKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNCR 6038
Score = 32.3 bits (72), Expect = 2.6
Identities = 16/45 (35%), Positives = 22/45 (48%), Gaps = 3/45 (6%)
Query: 836 PPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI 880
PP+ +P + K Y VGE V + P P +TW K G +I
Sbjct: 25192 PPEFTLPLYNKTAY---VGENVRFGVTITVHPEPHVTWYKSGQKI 25233
Score = 32.0 bits (71), Expect = 3.4
Identities = 27/97 (27%), Positives = 39/97 (40%), Gaps = 5/97 (5%)
Query: 249 KKSAAFAKILDPAYQVDKGGRVRFVVELAD-PKLEVKWYKNGQEIRPSTKYIFEHKGCQR 307
K++A K +V G +F E+ P + +W+K G+EI S K
Sbjct: 4333 KRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYIS 4392
Query: 308 ILFINNCQMTDDSEYYVTAGDE----KCSTELFVREP 340
L I Q+ D EY A +E C+ L V P
Sbjct: 4393 SLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVP 4429
Score = 31.6 bits (70), Expect = 4.5
Identities = 26/88 (29%), Positives = 33/88 (37%), Gaps = 4/88 (4%)
Query: 1052 PLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSP 1111
PL + I G A L C V + W N I D R + L I +
Sbjct: 2404 PLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHA 2463
Query: 1112 YDGGTYCCKAVNDLGTVEIECKLEVKVI 1139
D G Y K + +G VE C L V+ I
Sbjct: 2464 SDEGPY--KLI--VGRVETNCNLSVEKI 2487
Score = 31.2 bits (69), Expect = 5.9
Identities = 15/66 (22%), Positives = 30/66 (45%), Gaps = 1/66 (1%)
Query: 262 YQVDKGGRVRFVVE-LADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDS 320
Y + G ++ + + P+ + W K+G+ ++ +T+ E +L I D
Sbjct: 17824 YSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFG 17883
Query: 321 EYYVTA 326
+Y VTA
Sbjct: 17884 KYTVTA 17889
>gi|148839296 immunoglobulin-like and fibronectin type III domain
containing 1 [Homo sapiens]
Length = 868
Score = 239 bits (611), Expect = 8e-63
Identities = 216/812 (26%), Positives = 329/812 (40%), Gaps = 70/812 (8%)
Query: 348 LEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATK 407
L D GE L C ++ D WFK+G ++ + + +G H L I
Sbjct: 79 LADMEVQPGEAATLSCTLTSDLGPGTWFKDGVKLT--TQDGVIFKQDGLVHSLFITHVQG 136
Query: 408 ADAAEYSVMTTGGQSSAKLSVDLKPL-------KILTPLTDQTVNLGKEICLKCEISENI 460
A Y+ + QS A L+V P K+ PL V GK + +K ++
Sbjct: 137 TQAGRYTFVAGDQQSEATLTVQDSPTIAPDVTEKLREPL---VVKAGKPVIVKIPFQSHL 193
Query: 461 P--GKWTKNGLP-VQESDRLKVVHKGRIH-KLVIANALTEDEGDY--VFAPDAYNVTLPA 514
P W K+G V SDR V G + +L + +A +D G Y + +V
Sbjct: 194 PIQAAWRKDGAEVVGSSDREAQVDLGDGYTRLCLPSAGRKDCGQYSVTLRSEGGSVQAEL 253
Query: 515 KVHVI---DPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIM---E 568
+ VI DPP+ ++ D AG LR PP+ R + +
Sbjct: 254 TLQVIDKPDPPQGPMEVQDCHR-----AGVCLRWR-------PPRDNGGRTVECYVVERR 301
Query: 569 GSGR---IRTESYPDSSTLVIDIAERDDSGVYHINLK----NEAGEAHASIKVKVVD--F 619
+GR ++ P ST D A + Y ++ AGEA S ++ V
Sbjct: 302 QAGRSTWLKVGEAPADSTTFTD-AHVEPGRKYTFRVRAVTSEGAGEALESEEILVAPEAL 360
Query: 620 PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTF 679
P P AP + + W P G + ILGY IER+KK S+ W +N E +
Sbjct: 361 PKAPSAPAILSASSQGITLTWTAPRGPGSAHILGYLIERRKKGSNTWTAVNDQPVPERRW 420
Query: 680 EPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTD---TTVTM 736
+ +G YE R+ AV G +P PS PP L+ VTD T++T+
Sbjct: 421 TVADVRQGCQYEFRVTAVAPSGPGEPGPPSDAVFARDPMRPPGLVRNLQVTDRSNTSITL 480
Query: 737 RWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFT 796
W PD GYV+E C S W+ + + T +T
Sbjct: 481 SWAGPDTQEGDEAQGYVVELCSSDSL------------------QWLPCHVGTVPVTTYT 522
Query: 797 ITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEA 856
GL FVRV AVN G S+P + + PK + K +VG+
Sbjct: 523 AKGLRPGEGYFVRVTAVNEGGQSQPSALDTLVQAMPVTVCPKFLVDSSTKDLLTVKVGDT 582
Query: 857 VNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVD 916
V + + F+ P PE+TW KDG + K + + + T + I A S SG Y + ++
Sbjct: 583 VRVPVSFEAMPMPEVTWLKDGLPLPKRSVTV-TKDGLTQLLIPVAGLSDSGLYTVVLRTL 641
Query: 917 KFVETA-SIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKS 975
+ E A S I++ P P + +++ V W P D+ Y +
Sbjct: 642 QGKEVAHSFRIRVAACPQAPGPIHLQENVPGTVTAEWEPSPDEAQDVPLHYAVFTRSSAH 701
Query: 976 MEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAV-IARDGKIYK 1034
W + H T+ ++ G+EY+FRV ++N G S+ + ++ + RD K
Sbjct: 702 GPWHEAADRIHTNRFTLLGILPGHEYHFRVVAKNELGASKPSDTSQPWCIPRQRDRFTVK 761
Query: 1035 NPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYR 1094
P Y + D S+ P F L + G ++C+V+G+P+P +TW KN ++ +P
Sbjct: 762 APCYREPDLSQKPRFLVGLRSHLLPQGCECCMSCAVQGSPRPHVTWFKNDRSLEGNPAVY 821
Query: 1095 MFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLG 1126
GVC+L I SP D G Y A N LG
Sbjct: 822 STDLLGVCSLTIPSVSPKDSGEYKAVAENTLG 853
Score = 69.7 bits (169), Expect = 1e-11
Identities = 107/489 (21%), Positives = 178/489 (36%), Gaps = 51/489 (10%)
Query: 285 WYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIM- 343
W+K+G ++ IF+ G LFI + Q T Y AGD++ L V++ P +
Sbjct: 105 WFKDGVKLTTQDGVIFKQDGLVHSLFITHVQGTQAGRYTFVAGDQQSEATLTVQDSPTIA 164
Query: 344 --VTKQL-EDTTAYCGERVELECEV-SEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHI 399
VT++L E G+ V ++ S W K+G E++ ++ +
Sbjct: 165 PDVTEKLREPLVVKAGKPVIVKIPFQSHLPIQAAWRKDGAEVVGSSDREAQVDLGDGYTR 224
Query: 400 LIIEGATKADAAEYSV--MTTGGQSSAKLSVDL--KPLKILTPLTDQTV----------- 444
L + A + D +YSV + GG A+L++ + KP P+ Q
Sbjct: 225 LCLPSAGRKDCGQYSVTLRSEGGSVQAELTLQVIDKPDPPQGPMEVQDCHRAGVCLRWRP 284
Query: 445 ---NLGKEI-CLKCEISENIPGKWTKNGLPVQESDRLKVVH--KGRIHKLVIANALTEDE 498
N G+ + C E + W K G +S H GR + + +E
Sbjct: 285 PRDNGGRTVECYVVERRQAGRSTWLKVGEAPADSTTFTDAHVEPGRKYTFRVRAVTSEGA 344
Query: 499 GDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIA----GNKLRLEIPISGEPP 554
G+ + + + + P + IL T+T A G+ L I
Sbjct: 345 GEALESEEI--LVAPEALPKAPSAPAILSASSQGITLTWTAPRGPGSAHILGYLIERRKK 402
Query: 555 PKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKV 614
W+ + + P+ V D+ + + + +G
Sbjct: 403 GSNTWT-----------AVNDQPVPERRWTVADV-RQGCQYEFRVTAVAPSGPGEPGPPS 450
Query: 615 KVVDFPDPPVAP------TVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMR 668
V DP P VT+ + ++W P G GY +E S +W+
Sbjct: 451 DAVFARDPMRPPGLVRNLQVTDRSNTSITLSWAGPDTQEGDEAQGYVVELCSSDSLQWLP 510
Query: 669 LNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDS 728
+ TT+ K + G Y VR+ AVN G S+PS + VT P L VDS
Sbjct: 511 CHVGTVPVTTYTAKGLRPGEGYFVRVTAVNEGGQSQPSALDTLVQAMPVTVCPKFL-VDS 569
Query: 729 VTDTTVTMR 737
T +T++
Sbjct: 570 STKDLLTVK 578
Score = 31.6 bits (70), Expect = 4.5
Identities = 17/70 (24%), Positives = 33/70 (47%), Gaps = 1/70 (1%)
Query: 549 ISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEA 608
+ G P P W + D+++ EG+ + + +L I DSG Y +N G+A
Sbjct: 797 VQGSPRPHVTWFKNDRSL-EGNPAVYSTDLLGVCSLTIPSVSPKDSGEYKAVAENTLGQA 855
Query: 609 HASIKVKVVD 618
++ + V++
Sbjct: 856 VSTATLIVIE 865
>gi|110349721 titin isoform novex-3 [Homo sapiens]
Length = 5604
Score = 139 bits (350), Expect = 2e-32
Identities = 112/414 (27%), Positives = 188/414 (45%), Gaps = 21/414 (5%)
Query: 270 VRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDE 329
+ F V + + KW KNG EI+ + K K L I N D ++Y AG
Sbjct: 2986 ITFEVTVNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKA 3045
Query: 330 KCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRY 389
+ L+V I K ++D +R ECEVSE D V+W K+ +E+ R
Sbjct: 3046 TSTATLYVEARHIEFRKHIKDIKVLEKKRAMFECEVSEPDITVQWMKDDQEL--QITDRI 3103
Query: 390 RIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKE 449
+I+ E H L+I +DA +Y+V+ G S+AKL V+ + ++I + + V +
Sbjct: 3104 KIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEKQR 3163
Query: 450 ICLKCEISE-NIPGKWTKNGLPV--QESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPD 506
++ E++E ++ W K+G+ + Q +R K V + RIH++ I+ D G+Y F
Sbjct: 3164 AVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAG 3223
Query: 507 AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAI 566
++ V+ +PP++ L VTV +G R ISG P PK W + ++ +
Sbjct: 3224 RNRSSVTLYVNAPEPPQV----LQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLL 3279
Query: 567 MEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG----EAHASIKVKVVDFPD- 621
G + + TL++ A +D+ VY KN+ G A S++V V PD
Sbjct: 3280 STGF-KCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQ 3338
Query: 622 --PPVAPTVTEVGDDWCIMNWEPPAY----DGGSPILGYFIERKKKQSSRWMRL 669
P P + D +P + G + ++ + KK + SR+ R+
Sbjct: 3339 EMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRM 3392
Score = 136 bits (343), Expect = 1e-31
Identities = 105/376 (27%), Positives = 169/376 (44%), Gaps = 13/376 (3%)
Query: 247 EEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQ 306
+ K+ F + L +K F E ++P ++VKWYK+G E+ KY
Sbjct: 2169 QAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKV 2228
Query: 307 RILFINNCQMTDDSEY-YVTAGDE--KCSTELFVREPPIMVTKQLEDTTAYCGERVELEC 363
L I +D +Y V DE K + +L V + K+L+D ELEC
Sbjct: 2229 HFLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGELEC 2288
Query: 364 EVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSS 423
VS ++ KW+ N E+ +Y I + L ++ TK D EYS + G +++
Sbjct: 2289 IVSPENIEGKWYHNDVEL--KSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTT 2346
Query: 424 AKLSVDLKPLKILTPLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKVVHK 482
KL + +P+ IL L+DQ V G + L+ ++S E++ G W K+G VQ SDR+ +V
Sbjct: 2347 CKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVID 2406
Query: 483 GRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNK 542
+ H L+I + ED G+Y F A ++ +V V +D + V VI G K
Sbjct: 2407 KQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYS-----VDVITPLKDVNVIEGTK 2461
Query: 543 LRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLK 602
LE +S W D+ I + R++ LVI+ D G Y + +
Sbjct: 2462 AVLECKVSVPDVTSVKWYLNDEQI-KPDDRVQAIVKGTKQRLVINRTHASDEGPYKLIVG 2520
Query: 603 NEAGEAHASI-KVKVV 617
+ S+ K+K++
Sbjct: 2521 RVETNCNLSVEKIKII 2536
Score = 130 bits (328), Expect = 5e-30
Identities = 80/234 (34%), Positives = 120/234 (51%), Gaps = 8/234 (3%)
Query: 272 FVVELADPKLE-VKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEK 330
F VEL P ++ V+W KNG + + KY KG L I NC + D+S Y G
Sbjct: 2726 FTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGFRLGRLG 2785
Query: 331 CSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYR 390
S L V + + K+ +D TA V E VS D VKWF EI P K +R
Sbjct: 2786 ASARLHVET--VKIIKKPKDVTALENATVAFEVSVSHDTVPVKWFHKSVEIKPSDK--HR 2841
Query: 391 IRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEI 450
+ E K H L+++ + +DA EY+ + GQ K + ++ L I + + V K
Sbjct: 2842 LVSERKVHKLMLQNISPSDAGEYTAVV--GQLECKAKLFVETLHITKTMKNIEVPETKTA 2899
Query: 451 CLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF 503
+CE+S N+P W KNG+ ++ S++ K+V +G++H+L+I N TED +Y F
Sbjct: 2900 SFECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTF 2953
Score = 120 bits (301), Expect = 7e-27
Identities = 130/513 (25%), Positives = 208/513 (40%), Gaps = 41/513 (7%)
Query: 96 KGKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSF 155
KG+W+ + GKHL L S + + I K + G Y TYK S
Sbjct: 2649 KGEWL----RDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEY----TYKVATSKTSA 2700
Query: 156 DLEVH--ESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWEL 213
L+V + T N+ + + + +K V + E+ + V
Sbjct: 2701 KLKVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISV--- 2757
Query: 214 LKNAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVD--KGGRVR 271
K + Y I D RL R+ + KI+ V + V
Sbjct: 2758 ----KGTIYSLRIKNCAIVDESVYGFRLGRLGASARLHVETVKIIKKPKDVTALENATVA 2813
Query: 272 FVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKC 331
F V ++ + VKW+ EI+PS K+ + L + N +D EY G +C
Sbjct: 2814 FEVSVSHDTVPVKWFHKSVEIKPSDKHRLVSERKVHKLMLQNISPSDAGEYTAVVGQLEC 2873
Query: 332 STELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRI 391
+LFV + +TK +++ + ECEVS + W KNG EI K ++I
Sbjct: 2874 KAKLFVE--TLHITKTMKNIEVPETKTASFECEVSHFNVPSMWLKNGVEIEMSEK--FKI 2929
Query: 392 RVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEIC 451
V+GK H LII + D+AEY+ + Q SA L+V P+ I + L D +N ++
Sbjct: 2930 VVQGKLHQLIIMNTSTEDSAEYTFVCGNDQVSATLTV--TPIMITSMLKD--INAEEKDT 2985
Query: 452 LKCEISENIPG---KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPD-- 506
+ E++ N G KW KNG+ ++ +D+ ++ K H L I N D DY F
Sbjct: 2986 ITFEVTVNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKA 3045
Query: 507 AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAI 566
TL + I+ K I D + V+ + E +S EP W + D+
Sbjct: 3046 TSTATLYVEARHIEFRKHIKD-------IKVLEKKRAMFECEVS-EPDITVQWMKDDQE- 3096
Query: 567 MEGSGRIRTESYPDSSTLVIDIAERDDSGVYHI 599
++ + RI+ + L+I D+G Y +
Sbjct: 3097 LQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTV 3129
Score = 115 bits (287), Expect = 3e-25
Identities = 101/370 (27%), Positives = 158/370 (42%), Gaps = 34/370 (9%)
Query: 266 KGGRVRFVVELAD-----------------PKLEVKWYKNGQEIRPSTKYIFEHKGCQRI 308
+G V FV EL D +E KWY N E++ + KY + ++
Sbjct: 2263 EGAVVEFVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQN 2322
Query: 309 LFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSED 368
L + + D EY +K + +L ++ PI + + L D G+ V+LE +VS +
Sbjct: 2323 LTVKDVTKEDQGEYSFVIDGKKTTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLE 2382
Query: 369 DANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSV 428
W K+G+E+ P R I ++ + H+L+IE TK DA YS S V
Sbjct: 2383 SVEGVWMKDGQEV--QPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRV 2440
Query: 429 DLKPLKILTPLTDQTVNLGKEICLKCEIS--ENIPGKWTKNGLPVQESDRLKVVHKGRIH 486
+ + ++TPL D V G + L+C++S + KW N ++ DR++ + KG
Sbjct: 2441 SVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQ 2500
Query: 487 KLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLE 546
+LVI DEG Y V I I+ GL D T T +E
Sbjct: 2501 RLVINRTHASDEGPYKLIVGRVETNCNLSVEKIK----IIRGL-RDLTCTETQNVVFEVE 2555
Query: 547 IPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG 606
+ SG +W+ DK I + S + + E++ L + +DD G Y AG
Sbjct: 2556 LSHSG---IDVLWNFKDKEI-KPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTF----YAG 2607
Query: 607 EAHASIKVKV 616
E S K+ V
Sbjct: 2608 ENMTSGKLTV 2617
Score = 109 bits (272), Expect = 2e-23
Identities = 92/363 (25%), Positives = 161/363 (44%), Gaps = 18/363 (4%)
Query: 269 RVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGD 328
R F E+++P + V+W K+ QE++ + + + + L I + +M+D +Y V AG
Sbjct: 3074 RAMFECEVSEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGG 3133
Query: 329 EKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSR 388
+ +LFV + + ++ +R +E EV+EDD + W+K+G EI + R
Sbjct: 3134 NVSTAKLFVEGRDVRIRSIKKEVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQER 3193
Query: 389 YRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDL-KPLKILTPLTDQTVNLG 447
++ VE + H + I ++DA EY+ + +SS L V+ +P ++L L TV G
Sbjct: 3194 HKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSG 3253
Query: 448 KEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF-A 504
K IS K W K + + K +H G+ + L++ A ED Y A
Sbjct: 3254 KPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEA 3313
Query: 505 PDAYNVTLPAKVHVIDPPKIILDGLD-----------ADNTVTVIAGNKLRLEIPISGEP 553
+ Y V + ++ P+++ + +TVT G R + +SG
Sbjct: 3314 KNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVT-SEGQPARFQCRVSG-T 3371
Query: 554 PPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIK 613
K W DK I + S R + D+ L I A +D G Y N G+ ++
Sbjct: 3372 DLKVSWYSKDKKI-KPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTAN 3430
Query: 614 VKV 616
+ +
Sbjct: 3431 LSL 3433
Score = 107 bits (268), Expect = 5e-23
Identities = 123/468 (26%), Positives = 198/468 (42%), Gaps = 56/468 (11%)
Query: 196 RREVKQQEEE---PQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSA 252
R + K++ EE + EL K YE++ + +L K + EEKK+
Sbjct: 1998 RSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRK----TKDELLHWTKELTEEEKKAL 2053
Query: 253 AF-AKILDPAYQVDK-----------------------GGRVRFVVELAD-PKLEVKWYK 287
A KI P ++ DK G F V + P E +WYK
Sbjct: 2054 AEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYK 2113
Query: 288 NGQEIRPSTK---YIFEHKGCQRILFINNCQMTDDSEYYV----TAGDEKCSTELFVREP 340
NG +I S + Y E C+ L I + D + V AG+ L V+
Sbjct: 2114 NGVKIERSDRIYWYWPEDNVCE--LVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAK 2171
Query: 341 PIMV-TKQLEDTTAYCGERV-ELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKH 398
++ T++L+D A + + ECE SE VKW+K+G E+ G K YR+ + K H
Sbjct: 2172 QLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGDK--YRMHSDRKVH 2229
Query: 399 ILIIEGATKADAAEYS---VMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCE 455
L I +DA +YS V +++AKL V+ ++ + L D V L+C
Sbjct: 2230 FLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGELECI 2289
Query: 456 IS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPA 514
+S ENI GKW N + ++ + + + + L + + ED+G+Y F D T
Sbjct: 2290 VSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTT--C 2347
Query: 515 KVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIR 574
K+ + P IL GL V G+ ++LE+ +S E + +W + D ++ S R+
Sbjct: 2348 KLKMKPRPIAILQGLSDQK---VCEGDIVQLEVKVSLE-SVEGVWMK-DGQEVQPSDRVH 2402
Query: 575 TESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDP 622
S L+I+ ++D+G Y + + V VD P
Sbjct: 2403 IVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDVITP 2450
Score = 105 bits (263), Expect = 2e-22
Identities = 101/375 (26%), Positives = 158/375 (42%), Gaps = 21/375 (5%)
Query: 263 QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 322
+V +G V+ V+++ +E W K+GQE++PS + +L I + D Y
Sbjct: 2366 KVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNY 2425
Query: 323 YVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDD-ANVKWFKNGEEI 381
T ST V + V L+D G + LEC+VS D +VKW+ N E+I
Sbjct: 2426 SFTIPALGLSTSGRVSVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQI 2485
Query: 382 IPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTD 441
P R + V+G K L+I +D Y ++ +++ LSV+ +KI+ L D
Sbjct: 2486 --KPDDRVQAIVKGTKQRLVINRTHASDEGPYKLIVGRVETNCNLSVE--KIKIIRGLRD 2541
Query: 442 QTVNLGKEICLKCEISEN-IPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGD 500
T + + + E+S + I W ++ S + K+ G+I+KL + N + +DEG
Sbjct: 2542 LTCTETQNVVFEVELSHSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGK 2601
Query: 501 YVF--APDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAM 558
Y F + + L I P D TV E+ P K
Sbjct: 2602 YTFYAGENMTSGKLTVAGGAISKPL-------TDQTVAESQEAVFECEV---ANPDSKGE 2651
Query: 559 WSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVD 618
W R K + + IR+ES L+I + DD G Y K + A +KV+ V
Sbjct: 2652 WLRDGKH-LPLTNNIRSESDGHKRRLIIAATKLDDIGEY--TYKVATSKTSAKLKVEAVK 2708
Query: 619 FPDPPVAPTVTEVGD 633
TVTE D
Sbjct: 2709 IKKTLKNLTVTETQD 2723
Score = 77.8 bits (190), Expect = 5e-14
Identities = 66/264 (25%), Positives = 116/264 (43%), Gaps = 27/264 (10%)
Query: 263 QVDKGGRVRFVVELADPKLEVKWYKNGQEI----RPSTKYIFEHKGCQRILFINNCQMTD 318
QV + R E+ + ++ WYK+G EI + KY+ E + +FI+ + +D
Sbjct: 3157 QVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERR--IHRMFISETRQSD 3214
Query: 319 DSEYYVTAGDEKCSTELFVREP-PIMVTKQLEDTTAYCGERVELECEVS-EDDANVKWFK 376
EY AG + S L+V P P V ++L+ T G+ +S + W+K
Sbjct: 3215 AGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYK 3274
Query: 377 NGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAA--------EYSVMTTGGQSSAKL-- 426
+ + G K ++ +G+++ L++ A DAA +Y V TT S ++
Sbjct: 3275 EEQLLSTGFKCKF--LHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPE 3332
Query: 427 ------SVDLKPLKILTPLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKV 479
+ + P I+TPL D + G+ +C +S ++ W ++ S ++
Sbjct: 3333 VVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRM 3392
Query: 480 VHKGRIHKLVIANALTEDEGDYVF 503
++L IA A EDEG Y F
Sbjct: 3393 TQFEDTYQLEIAEAYPEDEGTYTF 3416
Score = 63.5 bits (153), Expect = 1e-09
Identities = 31/92 (33%), Positives = 43/92 (46%)
Query: 1047 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEI 1106
P L N I G + TL C + G P P +TW + I +++ G+ L I
Sbjct: 943 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMI 1002
Query: 1107 RKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1138
R+ D G + C AVN+ GTV C L V+V
Sbjct: 1003 REAFAEDSGRFTCSAVNEAGTVSTSCYLAVQV 1034
Score = 59.7 bits (143), Expect = 2e-08
Identities = 74/324 (22%), Positives = 129/324 (39%), Gaps = 19/324 (5%)
Query: 829 LVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQ--GKPRPELTWKKDGAEID----- 881
L +E P + P + + ++++ E ++V Q G P+P + WKK G +
Sbjct: 1069 LTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRY 1128
Query: 882 KNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIE 941
K N + E +I + A+ +G+Y + V+ +K ET S +++ ++K +
Sbjct: 1129 KVSYNKQTGECKLVISMTFAD--DAGEYTIVVR-NKHGET-SASASLLEEADYELLMKSQ 1184
Query: 942 DVWGENVALTWTPPKDDGNAAITGYTIQKADKK-SMEWFTVIEHYHRTSATITELVIGNE 1000
+T + G+ + +K+ E + + + + + V E
Sbjct: 1185 QEMLYQTQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDTVVVRTYVEDQE 1244
Query: 1001 YYFRVFSENMCGLSEDATM-TKESAVIARDGKIYKNPVYEDFDFSEAPM--FTQPLVNTY 1057
++ F E + E + T ++ DG+ + D SEA F + N
Sbjct: 1245 FHISSFEERLIKEIEYRIIKTTLEELLEEDGE---EKMAVDISESEAVESGFDSRIKNYR 1301
Query: 1058 AIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRM-FSNQGVCTLEIRKPSPYDGGT 1116
+ G T +C + G P PKI W K+ I RY+M F G +L I P D G
Sbjct: 1302 ILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGI 1361
Query: 1117 YCCKAVNDLGTVEIECKLEVKVIA 1140
Y A N G KL V+ A
Sbjct: 1362 YTAFASNIKGNAICSGKLYVEPAA 1385
Score = 57.0 bits (136), Expect = 1e-07
Identities = 43/167 (25%), Positives = 72/167 (43%), Gaps = 11/167 (6%)
Query: 345 TKQLEDTTAYCGERVELECEVSEDDA-NVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIE 403
T+ L+ G E +S V WF++G+ I +I + L I
Sbjct: 9 TQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIP 68
Query: 404 GATKADAAEYSVMTTGGQSSAKLSVDL------KPLKILTPLTDQTVNLGKEICLKCEIS 457
TKA++ YS+ T G A + +L P + L TV G ++ L+ ++
Sbjct: 69 AVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVT 128
Query: 458 ENIPG---KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 501
IP K+ ++G +Q S ++ +G ++ L+IA A ED G Y
Sbjct: 129 -GIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTY 174
Score = 54.7 bits (130), Expect = 5e-07
Identities = 52/221 (23%), Positives = 77/221 (34%), Gaps = 45/221 (20%)
Query: 920 ETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF 979
+TA D++++ RP P E W DG + YT +
Sbjct: 1472 QTARFDLKVVGRPMP------ETFWFH-----------DGQQIVNDYTHK---------- 1504
Query: 980 TVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYE 1039
VI+ S I + + V ++N G S + + AV
Sbjct: 1505 VVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAV-------------- 1550
Query: 1040 DFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDD--PRYRMFS 1097
+ PMF + L N G + GNP P I W+KN IV P+ R+
Sbjct: 1551 --EHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEG 1608
Query: 1098 NQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1138
+G L+I D Y A+N G CK+ V+V
Sbjct: 1609 TKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEV 1649
Score = 53.1 bits (126), Expect = 1e-06
Identities = 30/102 (29%), Positives = 42/102 (41%)
Query: 1035 NPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYR 1094
N E D P F +PL V G P P + W +NK + D R +
Sbjct: 5171 NEAIEPKDNEMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIK 5230
Query: 1095 MFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
M VC+LEI +GG Y C AVN +G + +++
Sbjct: 5231 MERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDI 5272
Score = 50.8 bits (120), Expect = 7e-06
Identities = 29/85 (34%), Positives = 42/85 (49%), Gaps = 1/85 (1%)
Query: 1043 FSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAI-VDDPRYRMFSNQGV 1101
F P F P+ + +A CSV G P P++ W K + I D+ +Y + +G
Sbjct: 5376 FEMPPRFIMPICDFKIPENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGS 5435
Query: 1102 CTLEIRKPSPYDGGTYCCKAVNDLG 1126
TL+IR D TY C+AVN +G
Sbjct: 5436 HTLKIRNVCLSDSATYRCRAVNCVG 5460
Score = 48.9 bits (115), Expect = 3e-05
Identities = 59/283 (20%), Positives = 97/283 (34%), Gaps = 70/283 (24%)
Query: 854 GEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQV 913
GE+V L G P P +TW ++ +I+
Sbjct: 957 GESVTLECHISGYPSPTVTWYREDYQIE-------------------------------- 984
Query: 914 KVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADK 973
+SID QI + G +++ E ++ T + + G + + Y +
Sbjct: 985 --------SSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ--- 1033
Query: 974 KSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIY 1033
V E + + + +TE E + F E+ + D ++T+E A Y
Sbjct: 1034 -------VSEEFEKETTAVTEKFTTEE---KRFVESRDVVMTDTSLTEEQAGPGEPAAPY 1083
Query: 1034 KNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRY 1093
T+P+V + G + C V GNPKP + W K+ V + RY
Sbjct: 1084 --------------FITKPVVQKL-VEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRY 1128
Query: 1094 RMFSNQ--GVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKL 1134
++ N+ G C L I D G Y N G L
Sbjct: 1129 KVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1171
Score = 47.4 bits (111), Expect = 8e-05
Identities = 28/96 (29%), Positives = 44/96 (45%), Gaps = 2/96 (2%)
Query: 1044 SEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDD--PRYRMFSNQGV 1101
++AP FTQPL + + G AT + G P P+++W ++ I P ++ + G
Sbjct: 3 TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGR 62
Query: 1102 CTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1137
L I + + G Y KA N G +L VK
Sbjct: 63 AKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98
Score = 46.6 bits (109), Expect = 1e-04
Identities = 36/105 (34%), Positives = 48/105 (45%), Gaps = 4/105 (3%)
Query: 512 LPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSG 571
+PA V + P ++ GL VTVI G + LE ISG P P W R D I E S
Sbjct: 932 VPAPVEIPVTPPTLVSGL---KNVTVIEGESVTLECHISGYPSPTVTWYREDYQI-ESSI 987
Query: 572 RIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKV 616
+ + L+I A +DSG + + NEAG S + V
Sbjct: 988 DFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 1032
Score = 45.1 bits (105), Expect = 4e-04
Identities = 66/261 (25%), Positives = 110/261 (42%), Gaps = 42/261 (16%)
Query: 272 FVVELAD-PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTA---- 326
F+VE+ P VKWY+N + P + E G L I+N Q + EY A
Sbjct: 5202 FIVEVEGLPVPGVKWYRNKSLLEPDERIKMERVGNVCSLEISNIQKGEGGEYMCHAVNII 5261
Query: 327 GDEK--CSTELFVRE-------PPI----MVTKQLEDTTAY---CGERVELECEVSEDDA 370
G+ K + ++ +E PP+ ++ LE TT+ + + LE E+SE D
Sbjct: 5262 GEAKSFANVDIMPQEERVVALPPPVTHQHVMEFDLEHTTSSRTPSPQEIVLEVELSEKD- 5320
Query: 371 NVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDL 430
VK F+ +I+ P+ K +++ + + ++ + G+ +L +DL
Sbjct: 5321 -VKEFEKQVKIVTVPEF-----TPDHKSMIVSLDVLPFNFVDPNMDSREGEDK-ELKIDL 5373
Query: 431 K----PLKILTPLTDQTVNLGKEICLKCEISENIPG---KWTKNGLPVQESDRLKVV--- 480
+ P + + P+ D + + KC + IP KW K + + E D +K V
Sbjct: 5374 EVFEMPPRFIMPICDFKIPENSDAVFKCSVI-GIPTPEVKWYKEYMCI-EPDNIKYVISE 5431
Query: 481 HKGRIHKLVIANALTEDEGDY 501
KG H L I N D Y
Sbjct: 5432 EKGS-HTLKIRNVCLSDSATY 5451
Score = 44.7 bits (104), Expect = 5e-04
Identities = 62/284 (21%), Positives = 105/284 (36%), Gaps = 51/284 (17%)
Query: 869 PELT--WKKDGAEID-KNQINIRNSETDTIIFIRKAERSHSGKYDL----QVKVDK-FVE 920
P++T W KD E+ ++I I+ + + I S +GKY + V K FVE
Sbjct: 3084 PDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVE 3143
Query: 921 TASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNA------AITGYTIQKADKK 974
+ I+ I + +++ + + + + +DD +A + +Q+ K
Sbjct: 3144 GRDVRIRSIKK-------EVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHK- 3195
Query: 975 SMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYK 1034
+ V HR + T EY F V N ++ +Y
Sbjct: 3196 ----YVVERRIHRMFISETRQSDAGEYTF-VAGRNRSSVT-----------------LYV 3233
Query: 1035 NPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYR 1094
N E P Q L +G A + G P+PKI+W K + + + +
Sbjct: 3234 NA-------PEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCK 3286
Query: 1095 MFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1138
+ TL + + P D Y C+A ND G L V+V
Sbjct: 3287 FLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEV 3330
Score = 44.3 bits (103), Expect = 7e-04
Identities = 29/98 (29%), Positives = 51/98 (52%), Gaps = 1/98 (1%)
Query: 534 TVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDD 593
++TV G+++RL++ ++G P P + R D A ++ S + D +L+I A +D
Sbjct: 112 SMTVRQGSQVRLQVRVTGIPTPVVKFYR-DGAEIQSSLDFQISQEGDLYSLLIAEAYPED 170
Query: 594 SGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEV 631
SG Y +N N G A ++ ++ V + P T T V
Sbjct: 171 SGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIV 208
Score = 44.3 bits (103), Expect = 7e-04
Identities = 23/79 (29%), Positives = 38/79 (48%)
Query: 1061 GYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCK 1120
G + L C + G P+P +TW +N V + + +++ L I+ + D G Y C
Sbjct: 4173 GDSIILECLISGEPQPVVTWFQNGVLLKQNQKFQFEEVNCSHQLYIKDVNSQDSGKYKCV 4232
Query: 1121 AVNDLGTVEIECKLEVKVI 1139
A N+ G VE L V+ +
Sbjct: 4233 AENNSGAVESVSDLTVEPV 4251
Score = 43.9 bits (102), Expect = 9e-04
Identities = 94/440 (21%), Positives = 160/440 (36%), Gaps = 71/440 (16%)
Query: 246 REEKKSAAFAKILDPAYQVDKGGRVRFVVELAD-PKLEVKWYKNGQEIRPSTKYIFEHKG 304
++EK+ +P +V +G RF + P+ +V WY NGQ IR S ++ + G
Sbjct: 1835 QKEKQKPDIVLYPEPV-RVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDG 1893
Query: 305 CQRILFINNCQMTDDSEYYVTAG------DEKCSTELFVREP------------------ 340
L I +C+ D E VTA + K E+ RE
Sbjct: 1894 I-HYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRPEFHVH 1952
Query: 341 --------------PIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGE-----EI 381
P+ T+ E ER+ E E + FK E
Sbjct: 1953 EPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEA 2012
Query: 382 IPGPKSRYRIRVEGKKHIL-------------IIEGATKADAAEYSV-MTTGGQSSAKLS 427
I + + R + E + +L + E KA A E + + T +LS
Sbjct: 2013 ITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELS 2072
Query: 428 VDLKPLKILTPLTDQTVNLGKEICLKCEI--SENIPGKWTKNGLPVQESDRLK-VVHKGR 484
++ KI + QTV G + + + + +W KNG+ ++ SDR+ +
Sbjct: 2073 PSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDN 2132
Query: 485 IHKLVIANALTEDEGDYVFAPDAYNVTLPAKVH---VIDPPKIILDGLDADNTVTVIAGN 541
+ +LVI + ED + A N+ H ++ ++I + + V
Sbjct: 2133 VCELVIRDVTAEDSASIMV--KAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDT 2190
Query: 542 KLRLEIPISGEPPPKAMWSRGDKAIMEGSG-RIRTE-SYPDSSTLVIDIAERDDSGVYHI 599
E S EP K W + + EG R+ ++ S L ID ++ +D +
Sbjct: 2191 MATFECETS-EPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLV 2249
Query: 600 NLKNEAGEAHASIKVKVVDF 619
+N A ++ VV+F
Sbjct: 2250 EDENVKTTAKLIVEGAVVEF 2269
Score = 43.9 bits (102), Expect = 9e-04
Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 1/79 (1%)
Query: 1059 IAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYC 1118
+ G A C V G P+PK+ W N I R+R+ G+ L+I YD G
Sbjct: 1853 LEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVK 1911
Query: 1119 CKAVNDLGTVEIECKLEVK 1137
A N G +E + KLE++
Sbjct: 1912 VTAENPEGVIEHKVKLEIQ 1930
Score = 43.1 bits (100), Expect = 0.001
Identities = 41/170 (24%), Positives = 67/170 (39%), Gaps = 16/170 (9%)
Query: 464 WTKNGLPVQESDRLKVVHK-GRIHKLVIANALTEDEGDYVFAPD--------AYNVTLPA 514
W +G + KVV K L+I A D G++ + +T+ A
Sbjct: 1490 WFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEA 1549
Query: 515 KVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGS-GRI 573
H + P + + V + G++L +++ +G P P +W + I+ +I
Sbjct: 1550 VEHQVKPMFV-----EKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKI 1604
Query: 574 RTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKV-VDFPDP 622
R E + L ID DS Y N+AG KV V V+F +P
Sbjct: 1605 RIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEP 1654
Score = 42.7 bits (99), Expect = 0.002
Identities = 33/111 (29%), Positives = 46/111 (41%), Gaps = 5/111 (4%)
Query: 1021 KESAVIARDGKI----YKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKP 1076
+E +A +GKI +K E EAP + + + G +A V G P P
Sbjct: 2048 EEKKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDP 2107
Query: 1077 KITWMKNKVAIVDDPR-YRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLG 1126
+ W KN V I R Y + VC L IR + D + KA+N G
Sbjct: 2108 ECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAG 2158
Score = 42.7 bits (99), Expect = 0.002
Identities = 36/121 (29%), Positives = 52/121 (42%), Gaps = 16/121 (13%)
Query: 1024 AVIARDGKIYKNPVYED-----------FDFSEA---PMFTQPLVNTYAIAGYNATLNCS 1069
AVIA+ K+ + + E+ F+F P F + + + YA G A C
Sbjct: 5477 AVIAKKSKVTLSSLMEELVLKSNYTDSFFEFQVVEGPPRFIKGISDCYAPIGTAAYFQCL 5536
Query: 1070 VRGNPKPKITWMKNKVAIVDDPRYRM-FSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTV 1128
VRG+P+P + W K+ +V R+ + S G L I D G Y C A N G
Sbjct: 5537 VRGSPRPTVYWYKDG-KLVQGRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMA 5595
Query: 1129 E 1129
E
Sbjct: 5596 E 5596
Score = 42.0 bits (97), Expect = 0.003
Identities = 27/94 (28%), Positives = 40/94 (42%), Gaps = 4/94 (4%)
Query: 1047 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGV----C 1102
P FTQ L Y + G C + P P++TW N I R + + +
Sbjct: 3504 PSFTQKLTFKYVLEGEPVVFTCRLIACPTPEMTWFHNNRPIPTGLRRIIKAESDLHHHSS 3563
Query: 1103 TLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
+LEI++ D G+Y A+N G+ E L V
Sbjct: 3564 SLEIKRVQDRDSGSYRLLAINSEGSAESTASLLV 3597
Score = 42.0 bits (97), Expect = 0.003
Identities = 23/91 (25%), Positives = 39/91 (42%)
Query: 1047 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEI 1106
P F Q + + G + C +G P+P +TW N + I + + + S + L +
Sbjct: 3944 PSFLQEIESQEVYEGDSCNFVCHFQGYPQPIVTWYNNDMPIPRNQNFIIHSLENYSILTL 4003
Query: 1107 RKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1137
+ G+ C N GTV+ L+VK
Sbjct: 4004 SSVHHQNEGSITCVLFNQYGTVKTTSMLKVK 4034
Score = 40.4 bits (93), Expect = 0.010
Identities = 73/318 (22%), Positives = 115/318 (36%), Gaps = 33/318 (10%)
Query: 831 KEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQ-GKPRPELTWKKDGAEIDKNQINIRN 889
K +E +RI K+ +V E V+ F+ + + W KDG EI+
Sbjct: 3139 KLFVEGRDVRIRSIKKEV---QVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHK 3195
Query: 890 SETDTII---FIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGE 946
+ I FI + +S +G+Y ++ T ++ P PPQ+++ E
Sbjct: 3196 YVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTL-----YVNAPEPPQVLQ------E 3244
Query: 947 NVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEY---YF 1003
+T K A+ I + + W+ E T L G EY
Sbjct: 3245 LQPVTVQSGKPARFCAV----ISGRPQPKISWYKE-EQLLSTGFKCKFLHDGQEYTLLLI 3299
Query: 1004 RVFSENM----CGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI 1059
F E+ C D + SA ++ + +P E + P PL +T
Sbjct: 3300 EAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYP--PAIITPLQDTVTS 3357
Query: 1060 AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCC 1119
G A C V G K++W I +RM + LEI + P D GTY
Sbjct: 3358 EGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTF 3416
Query: 1120 KAVNDLGTVEIECKLEVK 1137
A N +G V L ++
Sbjct: 3417 VASNAVGQVSSTANLSLE 3434
Score = 40.0 bits (92), Expect = 0.013
Identities = 44/211 (20%), Positives = 95/211 (45%), Gaps = 28/211 (13%)
Query: 245 RREEKKSAAFAKILDPAYQVD-------KGGRVRFVVELAD-PKLEVKWYKNGQEIRP-- 294
R EE + ++ P + + +G RF +++ P E W+ +GQ+I
Sbjct: 1442 RLEETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDY 1501
Query: 295 STKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFV--------REPPIMVTK 346
+ K + + G Q ++ + +D E+ V A + + + V + M +
Sbjct: 1502 THKVVIKEDGTQSLIIVP-ATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVE 1560
Query: 347 QLEDTTAYCGERVELECEVSED-DANVKWFKNGEEIIPGPKSRY-RIRVEGKK--HILII 402
+L++ G R+E++ + + + ++ W KN + I+P +Y +IR+EG K L I
Sbjct: 1561 KLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVP---HKYPKIRIEGTKGEAALKI 1617
Query: 403 EGATKADAAEY--SVMTTGGQSSAKLSVDLK 431
+ D+A Y + + G+ + + V+++
Sbjct: 1618 DSTVSQDSAWYTATAINKAGRDTTRCKVNVE 1648
Score = 39.3 bits (90), Expect = 0.022
Identities = 58/327 (17%), Positives = 107/327 (32%), Gaps = 45/327 (13%)
Query: 854 GEAVNLVIPFQGKPRPELTWKKDGAEIDKN---QINIRNSETDTIIFIRKAERSHSGKYD 910
G+ + G+P PE W DG +I + ++ I+ T ++I + A S SG++
Sbjct: 1471 GQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIV-PATPSDSGEWT 1529
Query: 911 L--QVKVDKFVETASIDIQIIDRPGPPQIV----------------KIEDVWGENVALTW 952
+ Q + + + + ++ ++ P V K+ N + W
Sbjct: 1530 VVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVW 1589
Query: 953 TPPKD------------DGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNE 1000
D +G I + W+T ++ T + E
Sbjct: 1590 LKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATA-INKAGRDTTRCKVNVE 1648
Query: 1001 YYFR--------VFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQP 1052
F + E A E + + ++ D + + P F +
Sbjct: 1649 VEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKK 1708
Query: 1053 LVNTYAIAGYNATLNCSVR--GNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPS 1110
L + A C + G+P + W+ + + R RM + G C+L+
Sbjct: 1709 LTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAY 1768
Query: 1111 PYDGGTYCCKAVNDLGTVEIECKLEVK 1137
D G C+A N GT L VK
Sbjct: 1769 SRDSGIITCRATNKYGTDHTSATLIVK 1795
Score = 38.9 bits (89), Expect = 0.028
Identities = 44/162 (27%), Positives = 69/162 (42%), Gaps = 13/162 (8%)
Query: 279 PKLEVKWYKNGQEIRPST--KYIFEHKGCQRILFINNCQMTDDSEYYVTA----GDEKCS 332
P EV W+++GQ I ST + L I + Y + A G +
Sbjct: 33 PVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKATNGSGQATST 92
Query: 333 TELFVR---EPPIMVTKQLEDTTAYCGERVELECEVSE-DDANVKWFKNGEEIIPGPKSR 388
EL V+ PP V ++L+ T G +V L+ V+ VK++++G EI
Sbjct: 93 AELLVKAETAPPNFV-QRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEI--QSSLD 149
Query: 389 YRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDL 430
++I EG + L+I A D+ YSV T A + +L
Sbjct: 150 FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAEL 191
Score = 38.5 bits (88), Expect = 0.037
Identities = 75/342 (21%), Positives = 130/342 (38%), Gaps = 50/342 (14%)
Query: 316 MTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDA-NVKW 374
MTD S AG + + F+ +P +V K +E G V C+V + +V W
Sbjct: 1064 MTDTSLTEEQAGPGEPAAPYFITKP--VVQKLVE------GGSVVFGCQVGGNPKPHVYW 1115
Query: 375 FKNGEEIIPGPKSRYRIRVEGKKHI----LIIEGATKADAAEYSVMTTG--GQSSAKLSV 428
K+G + G YR +V K L+I DA EY+++ G++SA S+
Sbjct: 1116 KKSGVPLTTG----YRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1171
Query: 429 DLKPLKILTPLTDQTVNLGKEICL---KCEISENIPGKWTKNGLPVQESDRLKVVHKGRI 485
+ L + Q + ++ + ++ E PG + + + ++ K
Sbjct: 1172 LEEADYELLMKSQQEMLYQTQVTAFVQEPKVGETAPG-FVYSEYEKEYEKEQALIRKKMA 1230
Query: 486 HKLVIANALTEDEGDYVFAPDA----------YNVTLPAKVHVIDPPKIILD-------- 527
V+ ED+ ++ + + TL + K+ +D
Sbjct: 1231 KDTVVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVE 1290
Query: 528 -GLDAD-NTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS-STL 584
G D+ ++ G + +SG P PK W + K I G R + + D ++L
Sbjct: 1291 SGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGE-RYQMDFLQDGRASL 1349
Query: 585 VIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAP 626
I + +D G+Y N G A S K+ V P AP
Sbjct: 1350 RIPVVLPEDEGIYTAFASNIKGNAICSGKLYV-----EPAAP 1386
Score = 37.4 bits (85), Expect = 0.082
Identities = 22/78 (28%), Positives = 39/78 (50%), Gaps = 7/78 (8%)
Query: 835 EPPKI--RIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ-INIRNSE 891
EPPK+ +P+H + R G+++ L G+P+P +TW ++G + +NQ
Sbjct: 4156 EPPKMLQEMPKHARC----REGDSIILECLISGEPQPVVTWFQNGVLLKQNQKFQFEEVN 4211
Query: 892 TDTIIFIRKAERSHSGKY 909
++I+ SGKY
Sbjct: 4212 CSHQLYIKDVNSQDSGKY 4229
Score = 37.0 bits (84), Expect = 0.11
Identities = 25/94 (26%), Positives = 40/94 (42%), Gaps = 1/94 (1%)
Query: 1047 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYR-MFSNQGVCTLE 1105
P+F V+ + G A + V G P P+ W + IV+D ++ + G +L
Sbjct: 1457 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLI 1516
Query: 1106 IRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVI 1139
I +P D G + A N G I L V+ +
Sbjct: 1517 IVPATPSDSGEWTVVAQNRAGRSSISVILTVEAV 1550
Score = 36.6 bits (83), Expect = 0.14
Identities = 53/275 (19%), Positives = 95/275 (34%), Gaps = 51/275 (18%)
Query: 340 PPIMVTKQLEDTTAYCGERVELECEVSE-DDANVKWFKNGEEIIPGPKSRYRIRVEGKKH 398
PP +V+ L++ T GE V LEC +S V W++ +I ++I +
Sbjct: 942 PPTLVSG-LKNVTVIEGESVTLECHISGYPSPTVTWYREDYQI--ESSIDFQITFQSGIA 998
Query: 399 ILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISE 458
L+I A D+ + T VN + C ++
Sbjct: 999 RLMIREAFAEDSGRF--------------------------TCSAVNEAGTVSTSCYLAV 1032
Query: 459 NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIAN-ALTEDEGDYVFAPDAYNVTLPAKVH 517
+ ++ K V E + +V+ + +LTE++ Y +T P
Sbjct: 1033 QVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQK 1092
Query: 518 VIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSG-RIRTE 576
+++ G + + G P P W + + G ++
Sbjct: 1093 LVE-------------------GGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYN 1133
Query: 577 SYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHAS 611
LVI + DD+G Y I ++N+ GE AS
Sbjct: 1134 KQTGECKLVISMTFADDAGEYTIVVRNKHGETSAS 1168
Score = 36.2 bits (82), Expect = 0.18
Identities = 25/111 (22%), Positives = 46/111 (41%), Gaps = 3/111 (2%)
Query: 339 EPPIMVTKQLEDTTAYCGERVELECEVS-EDDANVKWFKNGEEIIPGPKSRYRIRVEGKK 397
EPP M+ + + G+ + LEC +S E V WF+NG ++ +++
Sbjct: 4156 EPPKMLQEMPKHARCREGDSIILECLISGEPQPVVTWFQNG--VLLKQNQKFQFEEVNCS 4213
Query: 398 HILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGK 448
H L I+ D+ +Y + + + DL + Q N+G+
Sbjct: 4214 HQLYIKDVNSQDSGKYKCVAENNSGAVESVSDLTVEPVTYRENSQFENIGE 4264
Score = 35.8 bits (81), Expect = 0.24
Identities = 25/91 (27%), Positives = 42/91 (46%), Gaps = 1/91 (1%)
Query: 534 TVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS-STLVIDIAERD 592
+V V+ G+ E ISG P P+ W R + I + S+ D + L I +
Sbjct: 14 SVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKA 73
Query: 593 DSGVYHINLKNEAGEAHASIKVKVVDFPDPP 623
+SG Y + N +G+A ++ ++ V PP
Sbjct: 74 NSGRYSLKATNGSGQATSTAELLVKAETAPP 104
Score = 35.0 bits (79), Expect = 0.41
Identities = 23/91 (25%), Positives = 37/91 (40%)
Query: 1047 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEI 1106
P F Q L + G L V G P P + + ++ I +++ + +L I
Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLI 163
Query: 1107 RKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1137
+ P D GTY A N +G +L V+
Sbjct: 164 AEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 35.0 bits (79), Expect = 0.41
Identities = 15/57 (26%), Positives = 28/57 (49%)
Query: 278 DPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTE 334
+P+ V W++NG ++ + K+ FE C L+I + D +Y A + + E
Sbjct: 4185 EPQPVVTWFQNGVLLKQNQKFQFEEVNCSHQLYIKDVNSQDSGKYKCVAENNSGAVE 4241
Score = 34.7 bits (78), Expect = 0.53
Identities = 24/85 (28%), Positives = 41/85 (48%), Gaps = 3/85 (3%)
Query: 547 IPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG 606
+ + G P P W R +K+++E RI+ E + +L I ++ + G Y + N G
Sbjct: 5204 VEVEGLPVPGVKWYR-NKSLLEPDERIKMERVGNVCSLEISNIQKGEGGEYMCHAVNIIG 5262
Query: 607 EAHASIKVKVVDFPDPPVA--PTVT 629
EA + V ++ + VA P VT
Sbjct: 5263 EAKSFANVDIMPQEERVVALPPPVT 5287
Score = 33.9 bits (76), Expect = 0.91
Identities = 27/119 (22%), Positives = 51/119 (42%), Gaps = 11/119 (9%)
Query: 393 VEGKKHILIIEGATKADAAEYSVM-------TTGGQSSAKLSVDLKPLKILTPLTDQTVN 445
VE KK + + T + V+ T + A + + + P +++ L + TV
Sbjct: 896 VEVKKEVGVSITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVI 955
Query: 446 LGKEICLKCEISENIPGK---WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 501
G+ + L+C IS P W + ++ S ++ + I +L+I A ED G +
Sbjct: 956 EGESVTLECHIS-GYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRF 1013
Score = 33.5 bits (75), Expect = 1.2
Identities = 35/140 (25%), Positives = 63/140 (45%), Gaps = 11/140 (7%)
Query: 792 KTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIR 851
+ K TI + +KA N +G + + +LVK PP + L+ +R
Sbjct: 62 RAKLTIPAVTKANSGRYSLKATNGSGQATS---TAELLVKAETAPPNF--VQRLQSMTVR 116
Query: 852 RVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTI--IFIRKAERSHSGKY 909
+ G V L + G P P + + +DGAEI ++ ++ + S+ + + I +A SG Y
Sbjct: 117 Q-GSQVRLQVRVTGIPTPVVKFYRDGAEI-QSSLDFQISQEGDLYSLLIAEAYPEDSGTY 174
Query: 910 DLQV--KVDKFVETASIDIQ 927
+ V + TA + +Q
Sbjct: 175 SVNATNSVGRATSTAELLVQ 194
Score = 33.1 bits (74), Expect = 1.5
Identities = 21/96 (21%), Positives = 41/96 (42%), Gaps = 3/96 (3%)
Query: 847 QTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ---INIRNSETDTIIFIRKAER 903
Q+ + G G P PE++W +DG I + + I S+ + I +
Sbjct: 13 QSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTK 72
Query: 904 SHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVK 939
++SG+Y L+ T++ ++ + PP V+
Sbjct: 73 ANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQ 108
Score = 33.1 bits (74), Expect = 1.5
Identities = 21/93 (22%), Positives = 39/93 (41%), Gaps = 1/93 (1%)
Query: 538 IAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVY 597
+ G R ++ + G P P+ W + I+ + +L+I A DSG +
Sbjct: 1469 LEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEW 1528
Query: 598 HINLKNEAGEAHASIKVKVVDFPDPPVAPTVTE 630
+ +N AG + S+ + V+ + V P E
Sbjct: 1529 TVVAQNRAGRSSISV-ILTVEAVEHQVKPMFVE 1560
Score = 33.1 bits (74), Expect = 1.5
Identities = 19/61 (31%), Positives = 27/61 (44%), Gaps = 1/61 (1%)
Query: 1064 ATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVN 1123
AT C P K+ W K+ + + + +YRM S++ V L I D Y C V
Sbjct: 2192 ATFECET-SEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVE 2250
Query: 1124 D 1124
D
Sbjct: 2251 D 2251
Score = 33.1 bits (74), Expect = 1.5
Identities = 17/55 (30%), Positives = 28/55 (50%), Gaps = 1/55 (1%)
Query: 854 GEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ-INIRNSETDTIIFIRKAERSHSG 907
G++ N V FQG P+P +TW + I +NQ I + E +I+ + + G
Sbjct: 3958 GDSCNFVCHFQGYPQPIVTWYNNDMPIPRNQNFIIHSLENYSILTLSSVHHQNEG 4012
Score = 33.1 bits (74), Expect = 1.5
Identities = 24/94 (25%), Positives = 44/94 (46%), Gaps = 3/94 (3%)
Query: 540 GNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHI 599
G+ + LE ISGEP P W + + +++ + + + E S L I DSG Y
Sbjct: 4173 GDSIILECLISGEPQPVVTWFQ-NGVLLKQNQKFQFEEVNCSHQLYIKDVNSQDSGKYKC 4231
Query: 600 NLKNEAG--EAHASIKVKVVDFPDPPVAPTVTEV 631
+N +G E+ + + V+ V + + + E+
Sbjct: 4232 VAENNSGAVESVSDLTVEPVTYRENSQFENIGEI 4265
Score = 32.7 bits (73), Expect = 2.0
Identities = 23/89 (25%), Positives = 37/89 (41%), Gaps = 7/89 (7%)
Query: 824 YSQPILVKEIIEPPKIRIPRHLK--QTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEID 881
Y+ +++E P PR +K +G A +G PRP + W KDG +
Sbjct: 5500 YTDSFFEFQVVEGP----PRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWYKDGKLVQ 5555
Query: 882 KNQINIRNSETD-TIIFIRKAERSHSGKY 909
+ + S T +FI +S G+Y
Sbjct: 5556 GRRFTVEESGTGFHNLFITSLVKSDEGEY 5584
Score = 31.6 bits (70), Expect = 4.5
Identities = 26/88 (29%), Positives = 33/88 (37%), Gaps = 4/88 (4%)
Query: 1052 PLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSP 1111
PL + I G A L C V + W N I D R + L I +
Sbjct: 2450 PLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHA 2509
Query: 1112 YDGGTYCCKAVNDLGTVEIECKLEVKVI 1139
D G Y K + +G VE C L V+ I
Sbjct: 2510 SDEGPY--KLI--VGRVETNCNLSVEKI 2533
>gi|58331253 obscurin, cytoskeletal calmodulin and titin-interacting
RhoGEF isoform a [Homo sapiens]
Length = 6620
Score = 129 bits (323), Expect = 2e-29
Identities = 100/370 (27%), Positives = 164/370 (44%), Gaps = 19/370 (5%)
Query: 250 KSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRIL 309
K F K LD ++ G + E++DP+ V W K+G ++ PS KY F H R L
Sbjct: 2645 KPVVFLKALDDL-SAEERGTLALQCEVSDPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGL 2703
Query: 310 FINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDD 369
+++ D Y G E+ + V + + +TK+L+ GE EC +S +
Sbjct: 2704 VVHDVSPEDAGLYTCHVGSEETRARVRVHDLHVGITKRLKTMEVLEGESCSFECVLSHES 2763
Query: 370 AN--VKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLS 427
A+ W G+ + G SR++ +G+K+IL++ A +DA E G S A L
Sbjct: 2764 ASDPAMWTVGGKTV--GSSSRFQATRQGRKYILVVREAAPSDAGEVVFSVRGLTSKASLI 2821
Query: 428 VDLKPLKILTPLTDQTVNLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIH 486
V +P I+ PL DQ V G+++ L+CE+S P W K+ +++S + VV +G +
Sbjct: 2822 VRERPAAIIKPLEDQWVAPGEDVELRCELSRAGTPVHWLKDRKAIRKSQKYDVVCEGTMA 2881
Query: 487 KLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKII---LDGLDADNTVTVIAGNKL 543
LVI A +D G+Y +A T A +HV + L L + T + K
Sbjct: 2882 MLVIRGASLKDAGEYTCEVEASKST--ASLHVEEKANCFTEELTNLQVEEKGTAVFTCK- 2938
Query: 544 RLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKN 603
+ P W +G + SG+ + + L I E+ DS Y ++
Sbjct: 2939 ------TEHPAATVTWRKG-LLELRASGKHQPSQEGLTLRLTISALEKADSDTYTCDIGQ 2991
Query: 604 EAGEAHASIK 613
A ++
Sbjct: 2992 AQSRAQLLVQ 3001
Score = 127 bits (318), Expect = 8e-29
Identities = 99/387 (25%), Positives = 168/387 (43%), Gaps = 24/387 (6%)
Query: 243 RMRREEKKSAAFAK--ILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIF 300
R+R E K FAK + Q + G E+A + EV WYK+G+++ S+K
Sbjct: 880 RLRVSEPK-VVFAKEQLARRKLQAEAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVCM 938
Query: 301 EHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQL---EDTTAYCGE 357
E GC R L + D EY AG ++ S L V+EP ++ K + A G
Sbjct: 939 EATGCTRRLVVQQAGQADAGEYSCEAGGQRLSFHLDVKEPKVVFAKDQVAHSEVQAEAGA 998
Query: 358 RVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGK--KHILIIEGATKADAAEYSV 415
L CEV++ V W+K+G+++ S ++ VE K + L+++ A K DA +YS
Sbjct: 999 SATLSCEVAQAQTEVMWYKDGKKL----SSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSC 1054
Query: 416 MTTGGQSSAKLSVDLKPL---KILTPLTDQTVNLGKEICLKCEISE-NIPGKWTKNGLPV 471
G + S +L + + K + + G L CE+++ W K+G +
Sbjct: 1055 EARGQRVSFRLHITEPKMMFAKEQSVHNEVQAEAGASAMLSCEVAQAQTEVTWYKDGKKL 1114
Query: 472 QESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDA 531
S ++ + KG +LV+ A D G+Y V+ +H+ +P +
Sbjct: 1115 SSSSKVGMEVKGCTRRLVLPQAGKADAGEYSCEAGGQRVSF--HLHITEPKGVFAKEQSV 1172
Query: 532 DNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAER 591
N V AG L ++ +P + W + K + S ++R E + LV+ +
Sbjct: 1173 HNEVQAEAGTTAMLSCEVA-QPQTEVTWYKDGKK-LSSSSKVRMEVKGCTRRLVVQQVGK 1230
Query: 592 DDSGVYHINLKNEAGEAHASIKVKVVD 618
D+G Y EAG S ++ + +
Sbjct: 1231 ADAGEYSC----EAGGQRVSFQLHITE 1253
Score = 123 bits (308), Expect = 1e-27
Identities = 199/885 (22%), Positives = 335/885 (37%), Gaps = 104/885 (11%)
Query: 105 KAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTG 164
K GK L + T + + +A AG Y CE + SF L+V E
Sbjct: 925 KDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEAGGQ----RLSFHLDVKE--- 977
Query: 165 TTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLKN-------A 217
P + E Q +AG S L + Q E + L + A
Sbjct: 978 --PKVVFAKDQVAHSEVQAEAGA---SATLSCEVAQAQTEVMWYKDGKKLSSSLKVHVEA 1032
Query: 218 KPSEYEKIAFQYGITDL-------RGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRV 270
K + Q G TD RG + E K A + + Q + G
Sbjct: 1033 KGCRRRLVVQQAGKTDAGDYSCEARGQRVSFRLHITEPKMMFAKEQSVHNEVQAEAGASA 1092
Query: 271 RFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEK 330
E+A + EV WYK+G+++ S+K E KGC R L + D EY AG ++
Sbjct: 1093 MLSCEVAQAQTEVTWYKDGKKLSSSSKVGMEVKGCTRRLVLPQAGKADAGEYSCEAGGQR 1152
Query: 331 CSTELFVREPPIMVTKQL---EDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKS 387
S L + EP + K+ + A G L CEV++ V W+K+G+++ S
Sbjct: 1153 VSFHLHITEPKGVFAKEQSVHNEVQAEAGTTAMLSCEVAQPQTEVTWYKDGKKL--SSSS 1210
Query: 388 RYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSV-DLKPLKILTPLTDQTV-- 444
+ R+ V+G L+++ KADA EYS G + S +L + + K + L V
Sbjct: 1211 KVRMEVKGCTRRLVVQQVGKADAGEYSCEAGGQRVSFQLHITEPKAVFAKEQLVHNEVRT 1270
Query: 445 NLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF 503
G L CE+++ W K+G + S ++++ G + +LV+ A D G+Y
Sbjct: 1271 EAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTC 1330
Query: 504 APDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGD 563
+A L + V +P + A V AG L ++ + G
Sbjct: 1331 --EAGGQRLSFHLDVSEPKAVFAKEQLAHRKVQAEAGAIATLSCEVAQAQTEVTWYKDGK 1388
Query: 564 KAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPP 623
K + S ++R E+ + LV+ A + D+G Y EAG S + V +
Sbjct: 1389 K--LSSSSKVRMEAVGCTRRLVVQQACQADTGEYSC----EAGGQRLSFSLDVAE----- 1437
Query: 624 VAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKK 683
P V + ++ E A G S L + + + + W + K+ +F K
Sbjct: 1438 --PKVVFAKEQ--PVHREVQAQAGASTTLSCEVAQAQTE-VMWYKDG----KKLSFSSKV 1488
Query: 684 MIEGVAYEVRIF---AVNAIG--ISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRW 738
+E V R+ A A+ S + R L V P + + V
Sbjct: 1489 RMEAVGCTRRLVVQQAGQAVAGEYSCEAGSQRLSFHLHVAEPKAVFAKEQPASREVQA-- 1546
Query: 739 RPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTIT 798
E TSA S E +A ++ W K L +K +
Sbjct: 1547 --------------------EAGTSATLSCEVAQAQTEV---TWYKDGKKLSSSSKVRME 1583
Query: 799 GLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRV----G 854
+ ++ V+ AG K Q + + PK+ + +Q R V G
Sbjct: 1584 AVGCTRRLVVQEAGQADAGEYSCKAGDQRLSFHLHVAEPKVVFAK--EQPAHREVQAEAG 1641
Query: 855 EAVNLVIPFQGKPRPELTWKKDGAEI-DKNQINIRNSETDTIIFIRKAERSHSGKYDLQV 913
+ L + + E+TW KDG ++ +++ + + +++A ++ +G+Y +
Sbjct: 1642 ASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQADAGEYSCEA 1700
Query: 914 ---KVDKFVETASIDIQIIDRP--GPPQIVKIEDVWGENVALTWT 953
++ + A ++ QI +RP P +VK E++ LT T
Sbjct: 1701 GGQRLSFRLHVAELEPQISERPCRREPLVVKEH----EDIILTAT 1741
Score = 108 bits (270), Expect = 3e-23
Identities = 88/353 (24%), Positives = 153/353 (43%), Gaps = 14/353 (3%)
Query: 265 DKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYV 324
++GG F ++ + V W+++G ++PS K+ G L I++ + D + V
Sbjct: 1911 EEGGEATFQCVVSPSDVAVVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITV 1970
Query: 325 TAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPG 384
A S L VRE P++ K+LE T V LE E++ ++W +N + PG
Sbjct: 1971 EAEGASSSAALRVREAPVLFKKKLEPQTVEERSSVTLEVELTRPWPELRWTRNATALAPG 2030
Query: 385 PKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTV 444
I EG +H L++ AD + T ++ AKL+V+++ ++++ L
Sbjct: 2031 --KNVEIHAEGARHRLVLHNVGFADRGFFGCETPDDKTQAKLTVEMRQVRLVRGLQAVEA 2088
Query: 445 NLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF 503
++ ++S ++ G WT++GL Q+ + +G +H L ++ ED G VF
Sbjct: 2089 REQGTATMEVQLSHADVDGSWTRDGLRFQQGPTCHLAVRGPMHTLTLSGLRPEDSGLMVF 2148
Query: 504 APDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGD 563
A V A++ V + P L V K+ LE +S P W + D
Sbjct: 2149 --KAEGVHTSARLVVTELPVSFSRPL---QDVVTTEKEKVTLECELS-RPNVDVRWLK-D 2201
Query: 564 KAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKV 616
+ + + +L I E D GVY +A +A +S VKV
Sbjct: 2202 GVELRAGKTMAIAAQGACRSLTIYRCEFADQGVYVC----DAHDAQSSASVKV 2250
Score = 107 bits (268), Expect = 5e-23
Identities = 74/265 (27%), Positives = 120/265 (45%), Gaps = 10/265 (3%)
Query: 263 QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 322
Q + G E+A + EV WYK+G+++ S+K E GC R L + D EY
Sbjct: 1545 QAEAGTSATLSCEVAQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEY 1604
Query: 323 YVTAGDEKCSTELFVREPPIMVTKQL---EDTTAYCGERVELECEVSEDDANVKWFKNGE 379
AGD++ S L V EP ++ K+ + A G L CEV++ V W+K+G+
Sbjct: 1605 SCKAGDQRLSFHLHVAEPKVVFAKEQPAHREVQAEAGASATLSCEVAQAQTEVTWYKDGK 1664
Query: 380 EIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSV-DLKPLKILTP 438
++ S+ R+ G L+++ A +ADA EYS G + S +L V +L+P P
Sbjct: 1665 KL--SSSSKVRVEAVGCTRRLVVQQAGQADAGEYSCEAGGQRLSFRLHVAELEPQISERP 1722
Query: 439 LTDQ--TVNLGKEICLKCEISENIPG--KWTKNGLPVQESDRLKVVHKGRIHKLVIANAL 494
+ V ++I L ++ W K+G+ ++ S R + +G H L + A
Sbjct: 1723 CRREPLVVKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQ 1782
Query: 495 TEDEGDYVFAPDAYNVTLPAKVHVI 519
D Y A P +V +
Sbjct: 1783 VLDSAIYSCRVGAEGQDFPVQVEEV 1807
Score = 106 bits (265), Expect = 1e-22
Identities = 88/339 (25%), Positives = 149/339 (43%), Gaps = 14/339 (4%)
Query: 283 VKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPI 342
V+W+K + +R ++ G + L I D EY G E+ S L VR P
Sbjct: 3655 VEWWKGHETLRDGDRHSLRQDGARCELQIRGLVAEDAGEYLCMCGKERTSAMLTVRAMPS 3714
Query: 343 MVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILII 402
+ L + A G+ L CE+S+ A V+W K E + G R+ +R +G + L I
Sbjct: 3715 KFIEGLRNEEATEGDTATLWCELSKA-APVEWRKGHETLRDG--DRHSLRQDGSRCELQI 3771
Query: 403 EGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPG 462
G DA EYS + ++SA L+V P + + + +Q G L+CE+S+ P
Sbjct: 3772 RGLAVVDAGEYSCVCGQERTSATLTVRALPARFIEDVKNQEAREGATAVLQCELSKAAPV 3831
Query: 463 KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY--VFAPDAYNVTLPAKVHVID 520
+W K ++ DR + G +L I D G+Y V + + TL +
Sbjct: 3832 EWRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSCVCGQERTSATLTVRA---- 3887
Query: 521 PPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPD 580
P + + L ++ G+ L+ +S EP +WS+G ++ +GR
Sbjct: 3888 PQPVFREPL---QSLQAEEGSTATLQCELS-EPTATVVWSKGGLQ-LQANGRREPRLQGC 3942
Query: 581 SSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDF 619
++ LV+ +R+D+G Y ++A A ++ V F
Sbjct: 3943 TAELVLQDLQREDTGEYTCTCGSQATSATLTVTAAPVRF 3981
Score = 106 bits (264), Expect = 1e-22
Identities = 78/287 (27%), Positives = 128/287 (44%), Gaps = 10/287 (3%)
Query: 283 VKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPI 342
V+W K + +R +YI +G + L I M D EY G E+ S L +R P
Sbjct: 3479 VEWRKGPENLRDGDRYILRQEGTRCELQICGLAMADAGEYLCVCGQERTSATLTIRALPA 3538
Query: 343 MVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILII 402
+ +++ A G L+CE++ A V+W K E + G RY +R +G K L I
Sbjct: 3539 RFIEDVKNQEAREGATAVLQCELNSA-APVEWRKGSETLRDG--DRYSLRQDGTKCELQI 3595
Query: 403 EGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPG 462
G AD EYS + ++SA L+V P+K L ++ G L+CE+S+ P
Sbjct: 3596 RGLAMADTGEYSCVCGQERTSAMLTVRALPIKFTEGLRNEEATEGATAVLRCELSKMAPV 3655
Query: 463 KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPP 522
+W K +++ DR + G +L I + ED G+Y+ + V + P
Sbjct: 3656 EWWKGHETLRDGDRHSLRQDGARCELQIRGLVAEDAGEYLCMCGKERTSAMLTVRAM--P 3713
Query: 523 KIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEG 569
++GL + G+ L +S P + W +G + + +G
Sbjct: 3714 SKFIEGLRNEEAT---EGDTATLWCELSKAAPVE--WRKGHETLRDG 3755
Score = 105 bits (263), Expect = 2e-22
Identities = 95/351 (27%), Positives = 155/351 (44%), Gaps = 14/351 (3%)
Query: 268 GRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAG 327
G F EL+ EV+W NG + + + HKG + L + + Q D ++
Sbjct: 2573 GWASFSCELSHEDEEVEWSLNGMPLYNDSFHEISHKGRRHTLVLKSIQRADAGIVRASSL 2632
Query: 328 DEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKS 387
S L VR P++ K L+D +A + L+CEVS+ +A+V W K+G ++ GP
Sbjct: 2633 KVSTSARLEVRVKPVVFLKALDDLSAEERGTLALQCEVSDPEAHVVWRKDGVQL--GPSD 2690
Query: 388 RYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLG 447
+Y L++ + DA Y+ ++ A++ V + I L V G
Sbjct: 2691 KYDFLHTAGTRGLVVHDVSPEDAGLYTCHVGSEETRARVRVHDLHVGITKRLKTMEVLEG 2750
Query: 448 KEICLKCEISE---NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFA 504
+ +C +S + P WT G V S R + +GR + LV+ A D G+ VF+
Sbjct: 2751 ESCSFECVLSHESASDPAMWTVGGKTVGSSSRFQATRQGRKYILVVREAAPSDAGEVVFS 2810
Query: 505 PDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDK 564
+T A + V + P I+ L+ D V +LR E+ +G P W + K
Sbjct: 2811 --VRGLTSKASLIVRERPAAIIKPLE-DQWVAPGEDVELRCELSRAGTP---VHWLKDRK 2864
Query: 565 AIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVK 615
AI + S + + LVI A D+G Y + EA ++ AS+ V+
Sbjct: 2865 AIRK-SQKYDVVCEGTMAMLVIRGASLKDAGEYTCEV--EASKSTASLHVE 2912
Score = 105 bits (262), Expect = 2e-22
Identities = 71/245 (28%), Positives = 111/245 (45%), Gaps = 7/245 (2%)
Query: 265 DKGGRVRFVVELADPK--LEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 322
+ G R +L+D + V+W K G E+ KY +G R L I+ + D EY
Sbjct: 4080 ETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATRELLIHQLEAKDTGEY 4139
Query: 323 YVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDAN-VKWFKNGEEI 381
G +K + L V EP + + + L D E VE CEVS A V+W G +
Sbjct: 4140 ACVTGGQKTAASLRVTEPEVTIVRGLVDAEVTADEDVEFSCEVSRAGATGVQWCLQGLPL 4199
Query: 382 IPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTD 441
+ +R +G+ H L ++G T DA S SSA+L+V + IL PL D
Sbjct: 4200 QSNEVTEVAVR-DGRIHTLRLKGVTPEDAGTVSFHLGNHASSAQLTVRAPEVTILEPLQD 4258
Query: 442 QTVNLGKEICLKCEIS--ENIPGKWTKNGLPVQESDRLKV-VHKGRIHKLVIANALTEDE 498
++ G++ +C +S +W G+P+Q ++ + V +G +H L + ED
Sbjct: 4259 VQLSEGQDASFQCRLSRASGQEARWALGGVPLQANEMNDITVEQGTLHLLTLHKVTLEDA 4318
Query: 499 GDYVF 503
G F
Sbjct: 4319 GTVSF 4323
Score = 105 bits (261), Expect = 3e-22
Identities = 90/364 (24%), Positives = 150/364 (41%), Gaps = 12/364 (3%)
Query: 263 QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 322
Q G E+A + EV WYK+G+++ S+K E GC R L + EY
Sbjct: 1453 QAQAGASTTLSCEVAQAQTEVMWYKDGKKLSFSSKVRMEAVGCTRRLVVQQAGQAVAGEY 1512
Query: 323 YVTAGDEKCSTELFVREPPIMVTKQ---LEDTTAYCGERVELECEVSEDDANVKWFKNGE 379
AG ++ S L V EP + K+ + A G L CEV++ V W+K+G+
Sbjct: 1513 SCEAGSQRLSFHLHVAEPKAVFAKEQPASREVQAEAGTSATLSCEVAQAQTEVTWYKDGK 1572
Query: 380 EIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPL---KIL 436
++ S+ R+ G L+++ A +ADA EYS + S L V + K
Sbjct: 1573 KL--SSSSKVRMEAVGCTRRLVVQEAGQADAGEYSCKAGDQRLSFHLHVAEPKVVFAKEQ 1630
Query: 437 TPLTDQTVNLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALT 495
+ G L CE+++ W K+G + S +++V G +LV+ A
Sbjct: 1631 PAHREVQAEAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQ 1690
Query: 496 EDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPP 555
D G+Y + +A L ++HV + I + + V + L ++
Sbjct: 1691 ADAGEY--SCEAGGQRLSFRLHVAELEPQISERPCRREPLVVKEHEDIILTATLATPSAA 1748
Query: 556 KAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVK 615
W + D + S R T S D+ TL + A+ DS +Y + E + ++
Sbjct: 1749 TVTWLK-DGVEIRRSKRHETASQGDTHTLTVHGAQVLDSAIYSCRVGAEGQDFPVQVEEV 1807
Query: 616 VVDF 619
F
Sbjct: 1808 AAKF 1811
Score = 105 bits (261), Expect = 3e-22
Identities = 89/366 (24%), Positives = 152/366 (41%), Gaps = 16/366 (4%)
Query: 263 QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 322
Q ++G EL++P V W K G +++ + + +GC L + + Q D EY
Sbjct: 3900 QAEEGSTATLQCELSEPTATVVWSKGGLQLQANGRREPRLQGCTAELVLQDLQREDTGEY 3959
Query: 323 YVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEII 382
T G + S L V P+ ++L+ G L CE+S A+V+W K ++
Sbjct: 3960 TCTCGSQATSATLTVTAAPVRFLRELQHQEVDEGGTAHLCCELSRAGASVEWRKGSLQLF 4019
Query: 383 PGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQ 442
P K Y++ +G L++ G + DA +Y+ T QS A LSV + K T L
Sbjct: 4020 PCAK--YQMVQDGAAAELLVRGVEQEDAGDYTCDTGHTQSMASLSVRVPRPKFKTRLQSL 4077
Query: 443 TVNLGKEICLKCEISENIPG---KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEG 499
G L C++S+ G +W K G+ + + ++ +G +L+I +D G
Sbjct: 4078 EQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATRELLIHQLEAKDTG 4137
Query: 500 DYVFAPDAYNVTLPAKVHVIDPPKIILDGL-DADNTVTVIAGNKLRLEIPISGEPPPKAM 558
+Y A + V +P I+ GL DA+ V A + +S
Sbjct: 4138 EYACVTGGQKTA--ASLRVTEPEVTIVRGLVDAE----VTADEDVEFSCEVSRAGATGVQ 4191
Query: 559 WSRGDKAIMEGSGRIRTESYPDS--STLVIDIAERDDSGVYHINLKNEAGEAHASIKVKV 616
W + + S + + D TL + +D+G +L N A A +++
Sbjct: 4192 WCL--QGLPLQSNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSFHLGNHASSAQLTVRAPE 4249
Query: 617 VDFPDP 622
V +P
Sbjct: 4250 VTILEP 4255
Score = 104 bits (259), Expect = 5e-22
Identities = 89/333 (26%), Positives = 142/333 (42%), Gaps = 10/333 (3%)
Query: 283 VKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPI 342
V+WYK+ + PS K+ +G L I D Y AG STE+ V +
Sbjct: 2499 VQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRCQAGSAHSSTEVTVEAREV 2558
Query: 343 MVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILII 402
VT L+D A CE+S +D V+W NG + S + I +G++H L++
Sbjct: 2559 TVTGPLQDAEATEEGWASFSCELSHEDEEVEWSLNGMPLY--NDSFHEISHKGRRHTLVL 2616
Query: 403 EGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISE-NIP 461
+ +ADA + +SA+L V +KP+ L L D + + L+CE+S+
Sbjct: 2617 KSIQRADAGIVRASSLKVSTSARLEVRVKPVVFLKALDDLSAEERGTLALQCEVSDPEAH 2676
Query: 462 GKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDP 521
W K+G+ + SD+ +H LV+ + ED G Y + A+V V D
Sbjct: 2677 VVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYTCHVGSEETR--ARVRVHDL 2734
Query: 522 PKIILDGLDADNTVTVIAGNKLRLEIPISGE-PPPKAMWSRGDKAIMEGSGRIRTESYPD 580
I L T+ V+ G E +S E AMW+ G K + S R +
Sbjct: 2735 HVGITKRL---KTMEVLEGESCSFECVLSHESASDPAMWTVGGKTV-GSSSRFQATRQGR 2790
Query: 581 SSTLVIDIAERDDSGVYHINLKNEAGEAHASIK 613
LV+ A D+G +++ +A ++
Sbjct: 2791 KYILVVREAAPSDAGEVVFSVRGLTSKASLIVR 2823
Score = 102 bits (253), Expect = 3e-21
Identities = 86/314 (27%), Positives = 131/314 (41%), Gaps = 13/314 (4%)
Query: 263 QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 322
+V +GG L+ VKW +RP KY +G L + N + D Y
Sbjct: 3195 EVLEGGAATLRCVLSSVAAPVKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQDSGRY 3254
Query: 323 YVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEII 382
+ GD+ S L V P +L + A G L CE+S+ A V+W K E +
Sbjct: 3255 SCSFGDQTTSATLTVTALPAQFIGKLRNKEATEGATATLRCELSKA-APVEWRKGSETLR 3313
Query: 383 PGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQ 442
G RY +R +G L I G DAAEYS + ++SA L++ P + L Q
Sbjct: 3314 DG--DRYCLRQDGAMCELQIRGLAMVDAAEYSCVCGEERTSASLTIRPMPAHFIGRLRHQ 3371
Query: 443 TVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY- 501
G L+CE+S+ P +W K +++ DR + G + +L I D G+Y
Sbjct: 3372 ESIEGATATLRCELSKAAPVEWRKGRESLRDGDRHSLRQDGAVCELQICGLAVADAGEYS 3431
Query: 502 -VFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTV---TVIAGNKLRLEIPISGEPPPKA 557
V + + TL K P +GL + V T + +L P+ P+
Sbjct: 3432 CVCGEERTSATLTVKA----LPAKFTEGLRNEEAVEGATAMLWCELSKVAPVEWRKGPEN 3487
Query: 558 MWSRGDKAIMEGSG 571
+ GD+ I+ G
Sbjct: 3488 L-RDGDRYILRQEG 3500
Score = 99.8 bits (247), Expect = 1e-20
Identities = 99/402 (24%), Positives = 162/402 (40%), Gaps = 53/402 (13%)
Query: 253 AFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFIN 312
+F++ L +K +V EL+ P ++V+W K+G E+R +G R L I
Sbjct: 2167 SFSRPLQDVVTTEKE-KVTLECELSRPNVDVRWLKDGVELRAGKTMAIAAQGACRSLTIY 2225
Query: 313 NCQMTDDSEYYVTAGDEKCST-----------------------------------ELFV 337
C+ D Y A D + S +L V
Sbjct: 2226 RCEFADQGVYVCDAHDAQSSASVKVQGRTYTLIYRRVLAEDAGEIQFVAENAESRAQLRV 2285
Query: 338 REPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKK 397
+E P+ + + L D A R LEC+VS A V+WFK +E+ PGPK Y + +G
Sbjct: 2286 KELPVTLVRPLRDKIAMEKHRGVLECQVSRASAQVRWFKGSQELQPGPK--YELVSDGLY 2343
Query: 398 HILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCE-- 455
LII D Y+ ++SA+ V+ + + I+ L D TV +CE
Sbjct: 2344 RKLIISDVHAEDEDTYTCDAGDVKTSAQFFVEEQSITIVRGLQDVTVMEPAPAWFECETS 2403
Query: 456 ISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAK 515
I P KW +Q + + +G +H+L++ + G F + A+
Sbjct: 2404 IPSVRPPKWLLGKTVLQAGGNVGLEQEGTVHRLMLRRTCSTMTGPVHFTVGKSRSS--AR 2461
Query: 516 VHVIDPPKIILDGLDADNTVTVIAGNKLR-LEIPISGEPPPKAMWSRGDKAIMEGSGRIR 574
+ V D P ++ L+ G +L+ + + P PKA+ D + S + +
Sbjct: 2462 LVVSDIPVVLTRPLEPK------TGRELQSVVLSCDFRPAPKAVQWYKDDTPLSPSEKFK 2515
Query: 575 TESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKV 616
+ L I D+GVY + +AG AH+S +V V
Sbjct: 2516 MSLEGQMAELRILRLMPADAGVY----RCQAGSAHSSTEVTV 2553
Score = 96.3 bits (238), Expect = 1e-19
Identities = 63/220 (28%), Positives = 99/220 (45%), Gaps = 3/220 (1%)
Query: 283 VKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPI 342
V+W K + +R +Y G + L I+ + D EY G E+ S L VR P
Sbjct: 3831 VEWRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSCVCGQERTSATLTVRAPQP 3890
Query: 343 MVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILII 402
+ + L+ A G L+CE+SE A V W K G ++ R R++G L++
Sbjct: 3891 VFREPLQSLQAEEGSTATLQCELSEPTATVVWSKGGLQL--QANGRREPRLQGCTAELVL 3948
Query: 403 EGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISE-NIP 461
+ + D EY+ +SA L+V P++ L L Q V+ G L CE+S
Sbjct: 3949 QDLQREDTGEYTCTCGSQATSATLTVTAAPVRFLRELQHQEVDEGGTAHLCCELSRAGAS 4008
Query: 462 GKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 501
+W K L + + ++V G +L++ ED GDY
Sbjct: 4009 VEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDY 4048
Score = 95.1 bits (235), Expect = 3e-19
Identities = 68/263 (25%), Positives = 113/263 (42%), Gaps = 3/263 (1%)
Query: 239 KRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKY 298
+R R +K + F++ L A + +G + V E + + V W K+G+ +R S +
Sbjct: 3083 QRASAALRVTEKPSVFSRELTDA-TITEGEDLTLVCETSTCDIPVCWTKDGKTLRGSARC 3141
Query: 299 IFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGER 358
H+G + L I + D Y AG S+ + V P+ + L+D G
Sbjct: 3142 QLSHEGHRAQLLITGATLQDSGRYKCEAGGACSSSIVRVHARPVRFQEALKDLEVLEGGA 3201
Query: 359 VELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTT 418
L C +S A VKW + PG K Y +R EG L++ D+ YS
Sbjct: 3202 ATLRCVLSSVAAPVKWCYGNNVLRPGDK--YSLRQEGAMLELVVRNLRPQDSGRYSCSFG 3259
Query: 419 GGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLK 478
+SA L+V P + + L ++ G L+CE+S+ P +W K +++ DR
Sbjct: 3260 DQTTSATLTVTALPAQFIGKLRNKEATEGATATLRCELSKAAPVEWRKGSETLRDGDRYC 3319
Query: 479 VVHKGRIHKLVIANALTEDEGDY 501
+ G + +L I D +Y
Sbjct: 3320 LRQDGAMCELQIRGLAMVDAAEY 3342
Score = 94.7 bits (234), Expect = 4e-19
Identities = 70/254 (27%), Positives = 110/254 (43%), Gaps = 5/254 (1%)
Query: 248 EKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQR 307
E+ +A F ++L+P + GG V EL+ EV W ++R ++ +G R
Sbjct: 1805 EEVAAKFCRLLEPVCG-ELGGTVTLACELSPACAEVVWRCGNTQLRVGKRFQMVAEGPVR 1863
Query: 308 ILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIM-VTKQLEDTTAYCGERVELECEVS 366
L + + D EY + D+ S +L V P ++ L A G +C VS
Sbjct: 1864 SLTVLGLRAEDAGEYVCESRDDHTSAQLTVSVPRVVKFMSGLSTVVAEEGGEATFQCVVS 1923
Query: 367 EDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKL 426
D V WF++G + P K + I G H L I DA + +V G SSA L
Sbjct: 1924 PSDVAVVWFRDGALLQPSEK--FAISQSGASHSLTISDLVLEDAGQITVEAEGASSSAAL 1981
Query: 427 SVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPG-KWTKNGLPVQESDRLKVVHKGRI 485
V P+ L QTV + L+ E++ P +WT+N + +++ +G
Sbjct: 1982 RVREAPVLFKKKLEPQTVEERSSVTLEVELTRPWPELRWTRNATALAPGKNVEIHAEGAR 2041
Query: 486 HKLVIANALTEDEG 499
H+LV+ N D G
Sbjct: 2042 HRLVLHNVGFADRG 2055
Score = 94.4 bits (233), Expect = 6e-19
Identities = 84/341 (24%), Positives = 136/341 (39%), Gaps = 15/341 (4%)
Query: 283 VKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPI 342
V+W K + +R +Y G L I M D +EY G+E+ S L +R P
Sbjct: 3303 VEWRKGSETLRDGDRYCLRQDGAMCELQIRGLAMVDAAEYSCVCGEERTSASLTIRPMPA 3362
Query: 343 MVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILII 402
+L + G L CE+S+ A V+W K E + G R+ +R +G L I
Sbjct: 3363 HFIGRLRHQESIEGATATLRCELSKA-APVEWRKGRESLRDG--DRHSLRQDGAVCELQI 3419
Query: 403 EGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPG 462
G ADA EYS + ++SA L+V P K L ++ G L CE+S+ P
Sbjct: 3420 CGLAVADAGEYSCVCGEERTSATLTVKALPAKFTEGLRNEEAVEGATAMLWCELSKVAPV 3479
Query: 463 KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPP 522
+W K +++ DR + +G +L I D G+Y+ + + + P
Sbjct: 3480 EWRKGPENLRDGDRYILRQEGTRCELQICGLAMADAGEYLCVCGQERTSATLTIRAL-PA 3538
Query: 523 KIILD--GLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPD 580
+ I D +A T + +L P+ W +G + + +G R
Sbjct: 3539 RFIEDVKNQEAREGATAVLQCELNSAAPVE--------WRKGSETLRDGD-RYSLRQDGT 3589
Query: 581 SSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPD 621
L I D+G Y E A +++ + F +
Sbjct: 3590 KCELQIRGLAMADTGEYSCVCGQERTSAMLTVRALPIKFTE 3630
Score = 93.2 bits (230), Expect = 1e-18
Identities = 80/337 (23%), Positives = 146/337 (43%), Gaps = 11/337 (3%)
Query: 283 VKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPI 342
V W K+G EIR S ++ +G L ++ Q+ D + Y G E + V E
Sbjct: 1750 VTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQVLDSAIYSCRVGAEGQDFPVQVEEVAA 1809
Query: 343 MVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILII 402
+ LE G V L CE+S A V W ++ G R+++ EG L +
Sbjct: 1810 KFCRLLEPVCGELGGTVTLACELSPACAEVVWRCGNTQLRVG--KRFQMVAEGPVRSLTV 1867
Query: 403 EGATKADAAEYSVMTTGGQSSAKLSVDL-KPLKILTPLTDQTVNLGKEICLKCEIS-ENI 460
G DA EY + +SA+L+V + + +K ++ L+ G E +C +S ++
Sbjct: 1868 LGLRAEDAGEYVCESRDDHTSAQLTVSVPRVVKFMSGLSTVVAEEGGEATFQCVVSPSDV 1927
Query: 461 PGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVID 520
W ++G +Q S++ + G H L I++ + ED G +A + A + V +
Sbjct: 1928 AVVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQ--ITVEAEGASSSAALRVRE 1985
Query: 521 PPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPD 580
P + L+ TV + + LE+ ++ P P+ W+R A+ G + +
Sbjct: 1986 APVLFKKKLEPQ---TVEERSSVTLEVELT-RPWPELRWTRNATALAPGK-NVEIHAEGA 2040
Query: 581 SSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVV 617
LV+ D G + ++ +A +++++ V
Sbjct: 2041 RHRLVLHNVGFADRGFFGCETPDDKTQAKLTVEMRQV 2077
Score = 90.9 bits (224), Expect = 6e-18
Identities = 67/274 (24%), Positives = 115/274 (41%), Gaps = 6/274 (2%)
Query: 246 REEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGC 305
R + F K L+P V++ V VEL P E++W +N + P +G
Sbjct: 1982 RVREAPVLFKKKLEPQ-TVEERSSVTLEVELTRPWPELRWTRNATALAPGKNVEIHAEGA 2040
Query: 306 QRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEV 365
+ L ++N D + D+K +L V + + + L+ A +E ++
Sbjct: 2041 RHRLVLHNVGFADRGFFGCETPDDKTQAKLTVEMRQVRLVRGLQAVEAREQGTATMEVQL 2100
Query: 366 SEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAK 425
S D + W ++G GP +R G H L + G D+ G +SA+
Sbjct: 2101 SHADVDGSWTRDGLRFQQGPTCHLAVR--GPMHTLTLSGLRPEDSGLMVFKAEGVHTSAR 2158
Query: 426 LSVDLKPLKILTPLTDQTVNLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGR 484
L V P+ PL D +++ L+CE+S N+ +W K+G+ ++ + + +G
Sbjct: 2159 LVVTELPVSFSRPLQDVVTTEKEKVTLECELSRPNVDVRWLKDGVELRAGKTMAIAAQGA 2218
Query: 485 IHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHV 518
L I D+G YV DA++ A V V
Sbjct: 2219 CRSLTIYRCEFADQGVYVC--DAHDAQSSASVKV 2250
Score = 90.9 bits (224), Expect = 6e-18
Identities = 66/241 (27%), Positives = 108/241 (44%), Gaps = 5/241 (2%)
Query: 264 VDKGGRVRFVVELADPKLE-VKWYKNGQEIRPST-KYIFEHKGCQRILFINNCQMTDDSE 321
V +G F ++ E V W+ + + + I G +L + + D
Sbjct: 3016 VQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQPGGYHVLTLRQLALKDSGT 3075
Query: 322 YYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEI 381
Y AGD++ S L V E P + +++L D T GE + L CE S D V W K+G+ +
Sbjct: 3076 IYFEAGDQRASAALRVTEKPSVFSRELTDATITEGEDLTLVCETSTCDIPVCWTKDGKTL 3135
Query: 382 IPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTD 441
+R ++ EG + L+I GAT D+ Y G SS+ + V +P++ L D
Sbjct: 3136 --RGSARCQLSHEGHRAQLLITGATLQDSGRYKCEAGGACSSSIVRVHARPVRFQEALKD 3193
Query: 442 QTVNLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGD 500
V G L+C +S P KW ++ D+ + +G + +LV+ N +D G
Sbjct: 3194 LEVLEGGAATLRCVLSSVAAPVKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQDSGR 3253
Query: 501 Y 501
Y
Sbjct: 3254 Y 3254
Score = 88.2 bits (217), Expect = 4e-17
Identities = 88/374 (23%), Positives = 146/374 (39%), Gaps = 11/374 (2%)
Query: 248 EKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQR 307
E+K+ F + L QV++ G F + P V W K E+R S K+ +G
Sbjct: 2912 EEKANCFTEELTNL-QVEEKGTAVFTCKTEHPAATVTWRKGLLELRASGKHQPSQEGLTL 2970
Query: 308 ILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSE 367
L I+ + D Y G + +L V+ + + + LED G C +S
Sbjct: 2971 RLTISALEKADSDTYTCDIGQAQSRAQLLVQGRRVHIIEDLEDVDVQEGSSATFRCRISP 3030
Query: 368 DDAN-VKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKL 426
+ V WF + + + + G H+L + D+ ++SA L
Sbjct: 3031 ANYEPVHWFLDKTPLHANELNEIDAQ-PGGYHVLTLRQLALKDSGTIYFEAGDQRASAAL 3089
Query: 427 SVDLKPLKILTPLTDQTVNLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRI 485
V KP LTD T+ G+++ L CE S +IP WTK+G ++ S R ++ H+G
Sbjct: 3090 RVTEKPSVFSRELTDATITEGEDLTLVCETSTCDIPVCWTKDGKTLRGSARCQLSHEGHR 3149
Query: 486 HKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRL 545
+L+I A +D G Y + +VH P + +A + V+ G L
Sbjct: 3150 AQLLITGATLQDSGRYKCEAGGACSSSIVRVHA-RPVRF----QEALKDLEVLEGGAATL 3204
Query: 546 EIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEA 605
+S P W G+ + G + LV+ DSG Y + ++
Sbjct: 3205 RCVLSSVAAP-VKWCYGNNVLRPGD-KYSLRQEGAMLELVVRNLRPQDSGRYSCSFGDQT 3262
Query: 606 GEAHASIKVKVVDF 619
A ++ F
Sbjct: 3263 TSATLTVTALPAQF 3276
Score = 85.9 bits (211), Expect = 2e-16
Identities = 87/375 (23%), Positives = 152/375 (40%), Gaps = 17/375 (4%)
Query: 261 AYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMT-DD 319
A Q +GG V F V+L +W+ +GQ ++ S+ Y + L I +
Sbjct: 621 AVQAVEGGEVTFSVDLTVASAG-EWFLDGQALKASSVYEIHCDRTRHTLTIREVPASLHG 679
Query: 320 SEYYVTAGDEKCSTELFVREPPIMVTKQ-----LEDTTAYCGERVELECEVSEDDANVKW 374
++ A + S + VR P + + + A E +L E+S+ A V W
Sbjct: 680 AQLKFVANGIESSIRMEVRAAPGLTANKPPAAAAREVLARLHEEAQLLAELSDQAAAVTW 739
Query: 375 FKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLK 434
K+G + PGPK Y ++ + +L++ + DA Y ++ GG+ + +LSV
Sbjct: 740 LKDGRTLSPGPK--YEVQASAGRRVLLVRDVARDDAGLYECVSRGGRIAYQLSVQGLARF 797
Query: 435 ILTPLTDQTVN--LGKEICLKCEISE-NIPGKWTKNGLPVQES-DRLKVVHKGRIHKLVI 490
+ + V+ G +CE SE ++ W K+G+ + S +R G H+LV
Sbjct: 798 LHKDMAGSCVDAVAGGPAQFECETSEAHVHVHWYKDGMELGHSGERFLQEDVGTRHRLVA 857
Query: 491 ANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPIS 550
A +DEG Y +V ++ V +P + A + AG L ++
Sbjct: 858 ATVTRQDEGTYSCRVGEDSVDF--RLRVSEPKVVFAKEQLARRKLQAEAGASATLSCEVA 915
Query: 551 GEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHA 610
+ G K + S ++ E+ + LV+ A + D+G Y + H
Sbjct: 916 QAQTEVTWYKDGKK--LSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEAGGQRLSFHL 973
Query: 611 SIKVKVVDFPDPPVA 625
+K V F VA
Sbjct: 974 DVKEPKVVFAKDQVA 988
Score = 84.7 bits (208), Expect = 4e-16
Identities = 88/394 (22%), Positives = 152/394 (38%), Gaps = 36/394 (9%)
Query: 327 GDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDAN-VKWFKNGEEIIPGP 385
G+ S +L VR P + + + L+D G+ +C +S +W G +
Sbjct: 4235 GNHASSAQLTVRAPEVTILEPLQDVQLSEGQDASFQCRLSRASGQEARWALGGVPLQANE 4294
Query: 386 KSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVN 445
+ + +G H+L + T DA S S A+L V K ++ L +
Sbjct: 4295 MNDITVE-QGTLHLLTLHKVTLEDAGTVSFHVGTCSSEAQLKVTAKNT-VVRGLENVEAL 4352
Query: 446 LGKEICLKCEIS--ENIPGKWTKNGLPVQESDRLKVV--HKGRIHKLVIANALTEDEGDY 501
G E +C++S E W + PV S+ +VV G H L++ N +D
Sbjct: 4353 EGGEALFECQLSQPEVAAHTWLLDDEPVHTSENAEVVFFENGLRHLLLLKNLRPQDSCRV 4412
Query: 502 VF-----APDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPIS-GEPPP 555
F A+ ++ +++P K V AG + +S P
Sbjct: 4413 TFLAGDMVTSAFLTVRGWRLEILEPLK----------NAAVRAGAQACFTCTLSEAVPVG 4462
Query: 556 KAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVK 615
+A W A+ + L++ A+ +G + +A AS ++
Sbjct: 4463 EASWYINGAAVQPDDSDWTVTADGSHHALLLRSAQPHHAGEVTFACR----DAVASARLT 4518
Query: 616 VVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCK 675
V+ PDPP V ++W P DGG + GY +E K+ + +W LC
Sbjct: 4519 VLGLPDPPEDAEVVARSSHTVTLSWAAPMSDGGGGLCGYRVEVKEGATGQWR-----LCH 4573
Query: 676 ETTFEPKKMIEGVA----YEVRIFAVNAIGISKP 705
E P+ +++G+A Y R+ AV +G +P
Sbjct: 4574 ELVPGPECVVDGLAPGETYRFRVAAVGPVGAGEP 4607
Score = 82.0 bits (201), Expect = 3e-15
Identities = 75/342 (21%), Positives = 139/342 (40%), Gaps = 15/342 (4%)
Query: 271 RFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEK 330
+ + EL+D V W K+G+ + P KY + +R+L + + D Y + +
Sbjct: 725 QLLAELSDQAAAVTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECVSRGGR 784
Query: 331 CSTELFVREPPIMVTKQLEDT--TAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSR 388
+ +L V+ + K + + A G + ECE SE +V W+K+G E + R
Sbjct: 785 IAYQLSVQGLARFLHKDMAGSCVDAVAGGPAQFECETSEAHVHVHWYKDGME-LGHSGER 843
Query: 389 YRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQT----- 443
+ G +H L+ T+ D YS G+ S + + K++
Sbjct: 844 FLQEDVGTRHRLVAATVTRQDEGTYSCRV--GEDSVDFRLRVSEPKVVFAKEQLARRKLQ 901
Query: 444 VNLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV 502
G L CE+++ W K+G + S ++ + G +LV+ A D G+Y
Sbjct: 902 AEAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEY- 960
Query: 503 FAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRG 562
+ +A L + V +P + A + V AG L ++ + + MW +
Sbjct: 961 -SCEAGGQRLSFHLDVKEPKVVFAKDQVAHSEVQAEAGASATLSCEVA-QAQTEVMWYKD 1018
Query: 563 DKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNE 604
K + S ++ E+ LV+ A + D+G Y + +
Sbjct: 1019 GKK-LSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEARGQ 1059
Score = 79.0 bits (193), Expect = 2e-14
Identities = 93/405 (22%), Positives = 153/405 (37%), Gaps = 59/405 (14%)
Query: 266 KGGRVRFVVELADPKLEVK-WYKNGQEIRPS--TKYIFEHKGCQRILFINNCQMTDDSEY 322
+GG F +L+ P++ W + + + S + +F G + +L + N + D
Sbjct: 4353 EGGEALFECQLSQPEVAAHTWLLDDEPVHTSENAEVVFFENGLRHLLLLKNLRPQDSCRV 4412
Query: 323 YVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSE--DDANVKWFKNGEE 380
AGD S L VR + + + L++ G + C +SE W+ NG
Sbjct: 4413 TFLAGDMVTSAFLTVRGWRLEILEPLKNAAVRAGAQACFTCTLSEAVPVGEASWYINGAA 4472
Query: 381 IIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSV----DLKPLKIL 436
+ P S + + +G H L++ A A E + +SA+L+V D +
Sbjct: 4473 VQPDD-SDWTVTADGSHHALLLRSAQPHHAGEVTFACRDAVASARLTVLGLPDPPEDAEV 4531
Query: 437 TPLTDQTVNL---------GKEIC-LKCEISENIPGKW------------TKNGLPVQES 474
+ TV L G +C + E+ E G+W +GL E+
Sbjct: 4532 VARSSHTVTLSWAAPMSDGGGGLCGYRVEVKEGATGQWRLCHELVPGPECVVDGLAPGET 4591
Query: 475 DRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNT 534
R +V G + V LP V + +PPK + A +
Sbjct: 4592 YRFRVAAVGPVGA-------------------GEPVHLPQTVRLAEPPKPVPPQPSAPES 4632
Query: 535 VTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDS 594
V AG + LE+ + E + +W +G + I G GR S LVI +D
Sbjct: 4633 RQVAAGEDVSLELEVVAE-AGEVIWHKGMERIQPG-GRFEVVSQGRQQMLVIKGFTAEDQ 4690
Query: 595 GVYHINL-KNEAGEAHASIKV-----KVVDFPDPPVAPTVTEVGD 633
G YH L + A A+ +V V + P P + P + GD
Sbjct: 4691 GEYHCGLAQGSICPAAATFQVALSPASVDEAPQPSLPPEAAQEGD 4735
Score = 75.9 bits (185), Expect = 2e-13
Identities = 76/288 (26%), Positives = 112/288 (38%), Gaps = 25/288 (8%)
Query: 232 TDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVE----------LADPKL 281
T +L L+R R + A PA G R V E +PK
Sbjct: 214 TSTAALLAHLQRRREAMRAEGA------PASPPSTGTRTCTVTEGKHARLSCYVTGEPKP 267
Query: 282 EVKWYKNGQEIRPSTKYI-FEHKGCQRILFINNCQMTDDSEYYVTA----GDEKCSTELF 336
E W K+GQ + +++ +E +L I C+ +D Y TA G S +
Sbjct: 268 ETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVV 327
Query: 337 VREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGK 396
VREP + K+L+D E CEV + WFK EE ++Y I EG
Sbjct: 328 VREPAVPFKKRLQDLEVREKESATFLCEVPQPSTEAAWFK--EETRLWASAKYGIEEEGT 385
Query: 397 KHILIIEGATKADAAEYSVMT-TGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCE 455
+ L + + D A Y T G ++ A+L+V L+ L T V C++
Sbjct: 386 ERRLTVRNVSADDDAVYICETPEGSRTVAELAVQGNLLRKLPRKTAVRVGDTAMFCVELA 445
Query: 456 ISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF 503
+ P W +N V R+ + +G H L I+ ED G F
Sbjct: 446 VPVG-PVHWLRNQEEVVAGGRVAISAEGTRHTLTISQCCLEDVGQVAF 492
Score = 67.0 bits (162), Expect = 1e-10
Identities = 60/217 (27%), Positives = 84/217 (38%), Gaps = 33/217 (15%)
Query: 239 KRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKY 298
KRL+ + EK+SA F + E+ P E W+K + S KY
Sbjct: 337 KRLQDLEVREKESATF------------------LCEVPQPSTEAAWFKEETRLWASAKY 378
Query: 299 IFEHKGCQRILFINNCQMTDDSEYYV-TAGDEKCSTELFV-----REPPIMVTKQLEDTT 352
E +G +R L + N DD+ Y T + EL V R+ P ++ DT
Sbjct: 379 GIEEEGTERRLTVRNVSADDDAVYICETPEGSRTVAELAVQGNLLRKLPRKTAVRVGDTA 438
Query: 353 AYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAE 412
+C VEL V V W +N EE++ G R I EG +H L I D +
Sbjct: 439 MFC---VELAVPVGP----VHWLRNQEEVVAG--GRVAISAEGTRHTLTISQCCLEDVGQ 489
Query: 413 YSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKE 449
+ M Q+S + V L P D V E
Sbjct: 490 VAFMAGDCQTSTQFCVSAPRKPPLQPPVDPVVKARME 526
Score = 64.3 bits (155), Expect = 6e-10
Identities = 72/308 (23%), Positives = 115/308 (37%), Gaps = 50/308 (16%)
Query: 356 GERVELECE-VSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYS 414
G+ L C+ V V W K+ + + G +R+R+ +G + L I D+ +Y
Sbjct: 24 GKDATLSCQIVGNPTPQVSWEKDQQPVAAG--ARFRLAQDGDLYRLTILDLALGDSGQYV 81
Query: 415 VMTTGGQSSAKLSVDLK-----------PLKILTPLTDQTVNLGKEICLKCEI--SENIP 461
A +V L+ P +L P T V G E +C + S
Sbjct: 82 CRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRP-TSIRVREGSEATFRCRVGGSPRPA 140
Query: 462 GKWTKNGLPVQESD--RLKVVHKGRIHKLVIANALTEDEGDY-VFAPDAYNVTLPAKVHV 518
W+K+G + E D R++V G L I A D G Y V A + A V
Sbjct: 141 VSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALV 200
Query: 519 IDPPK------------------------IILDGLDAD------NTVTVIAGNKLRLEIP 548
+D + +G A T TV G RL
Sbjct: 201 VDSDAADTASRPGTSTAALLAHLQRRREAMRAEGAPASPPSTGTRTCTVTEGKHARLSCY 260
Query: 549 ISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEA 608
++GEP P+ +W + + + EG + E ++ L I ++ D G+Y N G+
Sbjct: 261 VTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQT 320
Query: 609 HASIKVKV 616
++S+ V V
Sbjct: 321 YSSVLVVV 328
Score = 63.9 bits (154), Expect = 8e-10
Identities = 52/197 (26%), Positives = 83/197 (42%), Gaps = 12/197 (6%)
Query: 444 VNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 501
V++GK+ L C+I N + W K+ PV R ++ G +++L I + D G Y
Sbjct: 21 VSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQY 80
Query: 502 VF-APDAYNVTLPAKVHVIDPPKIILDG----LDADNTVTVIAGNKLRLEIPISGEPPPK 556
V A +A A +D + L ++ V G++ + G P P
Sbjct: 81 VCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPA 140
Query: 557 AMWSRGDKAIMEGSG-RIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVK 615
WS+ + + E G R+R E ++S L I A D G Y + +N G A A+ +
Sbjct: 141 VSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALV 200
Query: 616 VVDFPDPPVAPTVTEVG 632
V D A T + G
Sbjct: 201 V----DSDAADTASRPG 213
Score = 56.6 bits (135), Expect = 1e-07
Identities = 50/185 (27%), Positives = 82/185 (44%), Gaps = 12/185 (6%)
Query: 439 LTDQTVNLGKEICLKCEISENIPG--KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTE 496
L D T LG+ + L C ++ W K+G VQ ++ +I ++LT
Sbjct: 6020 LADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTG 6079
Query: 497 -DEGDYVF--APDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEP 553
D G Y+ A A N + K+ V PP+ + + + G + I G P
Sbjct: 6080 VDSGQYMCFAASAAGNCSTLGKILVQVPPRFV----NKVRASPFVEGEDAQFTCTIEGAP 6135
Query: 554 PPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDI--AERDDSGVYHINLKNEAGEAHAS 611
P+ W + D A++ + +T S P S LV+ I A ++D G+Y L N G A AS
Sbjct: 6136 YPQIRWYK-DGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARAS 6194
Query: 612 IKVKV 616
++++
Sbjct: 6195 AELRI 6199
Score = 54.7 bits (130), Expect = 5e-07
Identities = 60/290 (20%), Positives = 103/290 (35%), Gaps = 29/290 (10%)
Query: 832 EIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI--DKNQINIRN 889
EI+EP LK +R +A + P E +W +GA + D + +
Sbjct: 4433 EILEP--------LKNAAVRAGAQACFTCTLSEAVPVGEASWYINGAAVQPDDSDWTVTA 4484
Query: 890 SETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVA 949
+ + +R A+ H+G+ + AS + ++ P PP+ ++ V
Sbjct: 4485 DGSHHALLLRSAQPHHAGEVTFACRD----AVASARLTVLGLPDPPEDAEVVARSSHTVT 4540
Query: 950 LTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSEN 1009
L+W P DG + GY ++ + + +W E + L G Y FRV +
Sbjct: 4541 LSWAAPMSDGGGGLCGYRVEVKEGATGQWRLCHELVPGPECVVDGLAPGETYRFRVAAVG 4600
Query: 1010 MCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCS 1069
G E + + + + P AP Q AG + +L
Sbjct: 4601 PVGAGEPVHLPQTVRLAEPPKPVPPQP--------SAPESRQ------VAAGEDVSLELE 4646
Query: 1070 VRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCC 1119
V ++ W K I R+ + S L I+ + D G Y C
Sbjct: 4647 VVAE-AGEVIWHKGMERIQPGGRFEVVSQGRQQMLVIKGFTAEDQGEYHC 4695
Score = 53.9 bits (128), Expect = 8e-07
Identities = 31/95 (32%), Positives = 51/95 (53%), Gaps = 2/95 (2%)
Query: 1043 FSEAPMF-TQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGV 1101
FS AP F T+P ++ G +ATL+C + GNP P+++W K++ + R+R+ + +
Sbjct: 6 FSGAPRFLTRPKAFVVSV-GKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDL 64
Query: 1102 CTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
L I + D G Y C+A N +G L+V
Sbjct: 65 YRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQV 99
Score = 53.1 bits (126), Expect = 1e-06
Identities = 32/94 (34%), Positives = 43/94 (45%), Gaps = 2/94 (2%)
Query: 1045 EAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKN--KVAIVDDPRYRMFSNQGVC 1102
+AP F + G AT C V G+P+P ++W K+ ++ D PR R+
Sbjct: 108 QAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEAS 167
Query: 1103 TLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
L IR P DGGTY +A N LG L V
Sbjct: 168 ALRIRAARPRDGGTYEVRAENPLGAASAAAALVV 201
Score = 52.4 bits (124), Expect = 2e-06
Identities = 81/369 (21%), Positives = 147/369 (39%), Gaps = 43/369 (11%)
Query: 356 GERVELECEVS-EDDANVKWFKNGEEIIPGPKSRYRIRVEGKKH-ILIIEGATKADAAEY 413
G+ L C V+ E W K+G+ + G R+ + + +++ +L I ++D Y
Sbjct: 252 GKHARLSCYVTGEPKPETVWKKDGQLVTEG--RRHVVYEDAQENFVLKILFCKQSDRGLY 309
Query: 414 SVMTTG--GQSSAKLSVDLKP--LKILTPLTDQTVNLGKEICLKCEISE-NIPGKWTKNG 468
+ + GQ+ + + V ++ + L D V + CE+ + + W K
Sbjct: 310 TCTASNLVGQTYSSVLVVVREPAVPFKKRLQDLEVREKESATFLCEVPQPSTEAAWFKEE 369
Query: 469 LPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF-APDAYNVTLPAKVHVIDPPKIILD 527
+ S + + +G +L + N +D+ Y+ P+ V +L
Sbjct: 370 TRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICETPEGSRTVAELAVQ-----GNLLR 424
Query: 528 GLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVID 587
L V V +E+ + P W R + ++ G GR+ + TL I
Sbjct: 425 KLPRKTAVRVGDTAMFCVELAV---PVGPVHWLRNQEEVVAG-GRVAISAEGTRHTLTIS 480
Query: 588 IAERDDSGVYHINLKNEAGEAHASIKVKVVDFP-----DPPVAPTVTEVGDDWCIMNWEP 642
+D G + AG+ S + V P PPV P V + I++W P
Sbjct: 481 QCCLEDVG----QVAFMAGDCQTSTQF-CVSAPRKPPLQPPVDPVVKARMESSVILSWSP 535
Query: 643 PAYDGGSPIL--GYFIERKKKQSSRWMRLNFDLCKETTF--EPKKMIEGVA----YEVRI 694
P + G P+ GY +E+KK + W+R C E + P+ + VA ++ R+
Sbjct: 536 PPH-GERPVTIDGYLVEKKKLGTYTWIR-----CHEAEWVATPELTVADVAEEGNFQFRV 589
Query: 695 FAVNAIGIS 703
A+N+ G S
Sbjct: 590 SALNSFGQS 598
Score = 51.6 bits (122), Expect = 4e-06
Identities = 30/92 (32%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Query: 1046 APMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSN-QGVCTL 1104
AP+F L N GY + +C V G P P + W K+ + +D Y + + QG L
Sbjct: 5125 APVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQL 5184
Query: 1105 EIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
I P D G Y C A N +G + +L V
Sbjct: 5185 IITAVVPADMGVYRCLAENSMGVSSTKAELRV 5216
Score = 50.1 bits (118), Expect = 1e-05
Identities = 30/93 (32%), Positives = 43/93 (46%), Gaps = 1/93 (1%)
Query: 1047 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSN-QGVCTLE 1105
P F + L + A G L C V G PKP I+W K+ A+ DP + + + G C L
Sbjct: 6014 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 6073
Query: 1106 IRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1138
+ + D G Y C A + G K+ V+V
Sbjct: 6074 LDSLTGVDSGQYMCFAASAAGNCSTLGKILVQV 6106
Score = 48.9 bits (115), Expect = 3e-05
Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 2/93 (2%)
Query: 1047 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFS--NQGVCTL 1104
P F + + + G +A C++ G P P+I W K+ + +++ S G+ L
Sbjct: 6108 PRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVL 6167
Query: 1105 EIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1137
IR S D G Y C+ VN LG+ +L ++
Sbjct: 6168 VIRAASKEDLGLYECELVNRLGSARASAELRIQ 6200
Score = 48.1 bits (113), Expect = 5e-05
Identities = 72/323 (22%), Positives = 123/323 (38%), Gaps = 63/323 (19%)
Query: 213 LLKNAKPSEYEKIAFQYG--ITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRV 270
LLKN +P + ++ F G +T ++ + E K+AA V G +
Sbjct: 4400 LLKNLRPQDSCRVTFLAGDMVTSAFLTVRGWRLEILEPLKNAA----------VRAGAQA 4449
Query: 271 RFVVELAD--PKLEVKWYKNGQEIRPS-TKYIFEHKGCQRILFINNCQMTDDSEYYVTAG 327
F L++ P E WY NG ++P + + G L + + Q E
Sbjct: 4450 CFTCTLSEAVPVGEASWYINGAAVQPDDSDWTVTADGSHHALLLRSAQPHHAGEVTFACR 4509
Query: 328 DEKCSTELFVR---EPPI---MVTKQLEDTT------------AYCGERVELECEVSEDD 369
D S L V +PP +V + T CG RVE++ +
Sbjct: 4510 DAVASARLTVLGLPDPPEDAEVVARSSHTVTLSWAAPMSDGGGGLCGYRVEVK-----EG 4564
Query: 370 ANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGG--------- 420
A +W + E++PGP+ +++G + + V G
Sbjct: 4565 ATGQW-RLCHELVPGPEC-------------VVDGLAPGETYRFRVAAVGPVGAGEPVHL 4610
Query: 421 QSSAKLSVDLKPLKILTPLTD-QTVNLGKEICLKCEI-SENIPGKWTKNGLPVQESDRLK 478
+ +L+ KP+ + + V G+++ L+ E+ +E W K +Q R +
Sbjct: 4611 PQTVRLAEPPKPVPPQPSAPESRQVAAGEDVSLELEVVAEAGEVIWHKGMERIQPGGRFE 4670
Query: 479 VVHKGRIHKLVIANALTEDEGDY 501
VV +GR LVI ED+G+Y
Sbjct: 4671 VVSQGRQQMLVIKGFTAEDQGEY 4693
Score = 48.1 bits (113), Expect = 5e-05
Identities = 37/159 (23%), Positives = 68/159 (42%), Gaps = 7/159 (4%)
Query: 279 PKLEVKWYKNGQEIRPSTKYI-FEHKGCQRILFINNCQMTDDSEY--YVTAGDEKCST-- 333
PK + WYK+G+ ++ +I E L +++ D +Y + + CST
Sbjct: 6041 PKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMCFAASAAGNCSTLG 6100
Query: 334 ELFVREPPIMVTKQLEDTTAYCGERVELECEV-SEDDANVKWFKNGEEIIPGPKSRYRIR 392
++ V+ PP V K + + GE + C + ++W+K+G + G K +
Sbjct: 6101 KILVQVPPRFVNK-VRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSE 6159
Query: 393 VEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLK 431
+L+I A+K D Y SA+ S +L+
Sbjct: 6160 PRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELR 6198
Score = 46.2 bits (108), Expect = 2e-04
Identities = 33/114 (28%), Positives = 47/114 (41%), Gaps = 3/114 (2%)
Query: 1016 DATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPK 1075
D +M K + I K YK V ++ E PMF+ +T A G L C V
Sbjct: 4869 DPSMDKAAVKIQAAFKGYK--VRKEMKQQEGPMFSHTFGDTEAQVGDALRLECVVASKAD 4926
Query: 1076 PKITWMKNKVAIVDDPRYRMFS-NQGVCTLEIRKPSPYDGGTYCCKAVNDLGTV 1128
+ W+K+ V + D + + G C+L I D G Y C+ N G V
Sbjct: 4927 VRARWLKDGVELTDGRHHHIDQLGDGTCSLLITGLDRADAGCYTCQVSNKFGQV 4980
Score = 46.2 bits (108), Expect = 2e-04
Identities = 74/353 (20%), Positives = 126/353 (35%), Gaps = 81/353 (22%)
Query: 341 PIMVTKQLEDTTAYCGERVELECEVS-EDDANVKWFKNGEEIIPGPKSRYRIRVEGKK-H 398
P+ +T +L++ G V +C V+ + +V+WFK+G+ + Y I + + H
Sbjct: 5126 PVFLT-ELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLL--EEDDHYMINEDQQGGH 5182
Query: 399 ILIIEGATKADAAEYSVMTTGGQ----SSAKLSVDLKPLKILTPL--------------- 439
LII AD Y + + A+L VDL T
Sbjct: 5183 QLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYL 5242
Query: 440 -------TDQTVNLGK--EICLKCEISENIPGK------------------WTKNGLPVQ 472
T+ T + G+ ++ + + PG W K+G P+
Sbjct: 5243 SSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLT 5302
Query: 473 ESDRLKVVHKGRIHKLVIANALTEDEGDY------------------VFAPDAYNVTLPA 514
S +++ K +H L I + ED G Y V PD +
Sbjct: 5303 ASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPAS 5362
Query: 515 KVH-VIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSR--GDKAIM---- 567
VH + PP++ L+ V G+ + + + G P P W R ++ ++
Sbjct: 5363 DVHEQLVPPRM----LERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGP 5418
Query: 568 EGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFP 620
+ G S S +++D+ R G Y N AG+A S + V P
Sbjct: 5419 DTPGYTVASSAQQHSLVLLDVG-RQHQGTYTCIASNAAGQALCSASLHVSGLP 5470
Score = 41.2 bits (95), Expect = 0.006
Identities = 46/174 (26%), Positives = 70/174 (40%), Gaps = 26/174 (14%)
Query: 704 KPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTS 763
+ ++ S L + PP V + + TVT+ W P G GL GY +E EG+T
Sbjct: 4509 RDAVASARLTVLGLPDPPEDAEVVARSSHTVTLSWAAPMSDGGGGLCGYRVE-VKEGATG 4567
Query: 764 AKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKY 823
W + + +L+ + + GL RV AV GA EP +
Sbjct: 4568 -----------------QWRLCH-ELVPGPECVVDGLAPGETYRFRVAAVGPVGAGEPVH 4609
Query: 824 YSQPILVKEIIEPPKIRIPRHLKQTYIRRV--GEAVNLVIPFQGKPRPELTWKK 875
Q + + EPPK +P R+V GE V+L + + E+ W K
Sbjct: 4610 LPQTV---RLAEPPK-PVPPQPSAPESRQVAAGEDVSLELEVVAE-AGEVIWHK 4658
Score = 39.7 bits (91), Expect = 0.017
Identities = 35/138 (25%), Positives = 59/138 (42%), Gaps = 8/138 (5%)
Query: 537 VIAGNKL-RLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSG 595
V G +L + ++ + G P P+ W + D + S IR TL I R+DSG
Sbjct: 5271 VAPGTRLAKFQLKVKGYPAPRLYWFK-DGQPLTASAHIRMTDKKILHTLEIISVTREDSG 5329
Query: 596 VYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDW----CIMNWEPPAYDGGSPI 651
Y + N G A++S ++ +V PD P ++V + + + P GS I
Sbjct: 5330 QYAAYISNAMGAAYSSARL-LVRGPDEPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSI 5388
Query: 652 -LGYFIERKKKQSSRWMR 668
+E + + W+R
Sbjct: 5389 TFSVKVEGRPVPTVHWLR 5406
Score = 38.5 bits (88), Expect = 0.037
Identities = 22/67 (32%), Positives = 34/67 (50%), Gaps = 1/67 (1%)
Query: 1061 GYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSN-QGVCTLEIRKPSPYDGGTYCC 1119
G +A L+C V G PKP+ W K+ + + R+ ++ + Q L+I D G Y C
Sbjct: 252 GKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTC 311
Query: 1120 KAVNDLG 1126
A N +G
Sbjct: 312 TASNLVG 318
Score = 37.0 bits (84), Expect = 0.11
Identities = 27/86 (31%), Positives = 43/86 (50%), Gaps = 3/86 (3%)
Query: 330 KCSTELFVREPPIMVTKQLEDTTAYCGERVELECEV-SEDDANVKWFKNGEEIIPGPKSR 388
K E+ +E P M + DT A G+ + LEC V S+ D +W K+G E+ G +
Sbjct: 4887 KVRKEMKQQEGP-MFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDG-RHH 4944
Query: 389 YRIRVEGKKHILIIEGATKADAAEYS 414
+ ++ L+I G +ADA Y+
Sbjct: 4945 HIDQLGDGTCSLLITGLDRADAGCYT 4970
Score = 36.6 bits (83), Expect = 0.14
Identities = 38/166 (22%), Positives = 61/166 (36%), Gaps = 20/166 (12%)
Query: 992 ITELVIGNEYYFRVFSENMCGLSE-------DATMTK-ESAVIARDGKIY---------- 1033
IT +V + +R +EN G+S D T T ++A A + Y
Sbjct: 5186 ITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLSSR 5245
Query: 1034 -KNPVYEDFDFSEAPMFTQPLVNTYAIAGYN-ATLNCSVRGNPKPKITWMKNKVAIVDDP 1091
+ D + P + L + G A V+G P P++ W K+ +
Sbjct: 5246 EQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASA 5305
Query: 1092 RYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1137
RM + + TLEI + D G Y N +G +L V+
Sbjct: 5306 HIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVR 5351
Score = 35.8 bits (81), Expect = 0.24
Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 2/71 (2%)
Query: 1049 FTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRK 1108
F L N A G ATL C + + + W K + D RY + + +C L+IR
Sbjct: 3276 FIGKLRNKEATEGATATLRCEL--SKAAPVEWRKGSETLRDGDRYCLRQDGAMCELQIRG 3333
Query: 1109 PSPYDGGTYCC 1119
+ D Y C
Sbjct: 3334 LAMVDAAEYSC 3344
Score = 35.8 bits (81), Expect = 0.24
Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 2/71 (2%)
Query: 1049 FTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRK 1108
F + + N A G A L C + N + W K + D RY + + C L+IR
Sbjct: 3540 FIEDVKNQEAREGATAVLQCEL--NSAAPVEWRKGSETLRDGDRYSLRQDGTKCELQIRG 3597
Query: 1109 PSPYDGGTYCC 1119
+ D G Y C
Sbjct: 3598 LAMADTGEYSC 3608
Score = 35.4 bits (80), Expect = 0.31
Identities = 22/85 (25%), Positives = 38/85 (44%), Gaps = 13/85 (15%)
Query: 833 IIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDG---AEIDKNQINIRN 889
++ P IR+ + T+ RVG G PRP ++W KDG E D ++ +
Sbjct: 113 LLRPTSIRVREGSEATFRCRVG----------GSPRPAVSWSKDGRRLGEPDGPRVRVEE 162
Query: 890 SETDTIIFIRKAERSHSGKYDLQVK 914
+ + IR A G Y+++ +
Sbjct: 163 LGEASALRIRAARPRDGGTYEVRAE 187
Score = 35.4 bits (80), Expect = 0.31
Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 2/71 (2%)
Query: 1049 FTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRK 1108
FT+ L N A G A L C + + + W K + D R+ + + C L+IR
Sbjct: 3628 FTEGLRNEEATEGATAVLRCEL--SKMAPVEWWKGHETLRDGDRHSLRQDGARCELQIRG 3685
Query: 1109 PSPYDGGTYCC 1119
D G Y C
Sbjct: 3686 LVAEDAGEYLC 3696
Score = 34.7 bits (78), Expect = 0.53
Identities = 20/64 (31%), Positives = 32/64 (50%), Gaps = 1/64 (1%)
Query: 1058 AIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTY 1117
A AG +ATL+C V + ++TW K+ + + RM + L +++ D G Y
Sbjct: 1546 AEAGTSATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEY 1604
Query: 1118 CCKA 1121
CKA
Sbjct: 1605 SCKA 1608
Score = 34.3 bits (77), Expect = 0.69
Identities = 18/62 (29%), Positives = 30/62 (48%), Gaps = 2/62 (3%)
Query: 1058 AIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTY 1117
+I G ATL C + + + W K + ++ D R+ + + VC L+I + D G Y
Sbjct: 3373 SIEGATATLRCEL--SKAAPVEWRKGRESLRDGDRHSLRQDGAVCELQICGLAVADAGEY 3430
Query: 1118 CC 1119
C
Sbjct: 3431 SC 3432
Score = 34.3 bits (77), Expect = 0.69
Identities = 21/71 (29%), Positives = 31/71 (43%), Gaps = 2/71 (2%)
Query: 1049 FTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRK 1108
F + L N A G ATL C + + + W K + D R+ + + C L+IR
Sbjct: 3716 FIEGLRNEEATEGDTATLWCEL--SKAAPVEWRKGHETLRDGDRHSLRQDGSRCELQIRG 3773
Query: 1109 PSPYDGGTYCC 1119
+ D G Y C
Sbjct: 3774 LAVVDAGEYSC 3784
Score = 34.3 bits (77), Expect = 0.69
Identities = 17/59 (28%), Positives = 29/59 (49%), Gaps = 2/59 (3%)
Query: 853 VGEAVNLVIPFQGKPRPELTWKKDG--AEIDKNQINIRNSETDTIIFIRKAERSHSGKY 909
+GE V L G P+P ++W KDG ++D + I I + + + + SG+Y
Sbjct: 6027 LGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQY 6085
Score = 33.5 bits (75), Expect = 1.2
Identities = 20/83 (24%), Positives = 36/83 (43%), Gaps = 1/83 (1%)
Query: 1048 MFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIR 1107
+ T+PL + L+C R PK + W K+ + +++M + L I
Sbjct: 2470 VLTRPLEPKTGRELQSVVLSCDFRPAPKA-VQWYKDDTPLSPSEKFKMSLEGQMAELRIL 2528
Query: 1108 KPSPYDGGTYCCKAVNDLGTVEI 1130
+ P D G Y C+A + + E+
Sbjct: 2529 RLMPADAGVYRCQAGSAHSSTEV 2551
Score = 33.5 bits (75), Expect = 1.2
Identities = 20/80 (25%), Positives = 34/80 (42%), Gaps = 1/80 (1%)
Query: 1051 QPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPS 1110
+PL + + G + L C + P + W+K++ AI +Y + + L IR S
Sbjct: 2831 KPLEDQWVAPGEDVELRCELSRAGTP-VHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGAS 2889
Query: 1111 PYDGGTYCCKAVNDLGTVEI 1130
D G Y C+ T +
Sbjct: 2890 LKDAGEYTCEVEASKSTASL 2909
Score = 33.1 bits (74), Expect = 1.5
Identities = 19/64 (29%), Positives = 30/64 (46%), Gaps = 1/64 (1%)
Query: 1058 AIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTY 1117
A AG A L+C V P+ ++TW K+ + + RM L +++ D G Y
Sbjct: 1178 AEAGTTAMLSCEV-AQPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEY 1236
Query: 1118 CCKA 1121
C+A
Sbjct: 1237 SCEA 1240
Score = 32.7 bits (73), Expect = 2.0
Identities = 19/71 (26%), Positives = 30/71 (42%), Gaps = 5/71 (7%)
Query: 1066 LNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDL 1125
L C V +P+ + W K+ V + +Y G L + SP D G Y C +
Sbjct: 2666 LQCEV-SDPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYTC----HV 2720
Query: 1126 GTVEIECKLEV 1136
G+ E ++ V
Sbjct: 2721 GSEETRARVRV 2731
Score = 32.3 bits (72), Expect = 2.6
Identities = 20/92 (21%), Positives = 45/92 (48%), Gaps = 3/92 (3%)
Query: 854 GEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINI--RNSETDTIIFIRKAERSHSGKYDL 911
G+ L G+P+PE WKKDG + + + ++ +++ + ++ I ++S G Y
Sbjct: 252 GKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTC 311
Query: 912 QVKVDKFVETASIDIQIIDRPGPPQIVKIEDV 943
+ +T S + ++ P P +++D+
Sbjct: 312 TAS-NLVGQTYSSVLVVVREPAVPFKKRLQDL 342
Score = 32.3 bits (72), Expect = 2.6
Identities = 18/61 (29%), Positives = 29/61 (47%)
Query: 263 QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 322
QV G V +E+ EV W+K + I+P ++ +G Q++L I D EY
Sbjct: 4634 QVAAGEDVSLELEVVAEAGEVIWHKGMERIQPGGRFEVVSQGRQQMLVIKGFTAEDQGEY 4693
Query: 323 Y 323
+
Sbjct: 4694 H 4694
Score = 32.0 bits (71), Expect = 3.4
Identities = 22/82 (26%), Positives = 39/82 (47%), Gaps = 2/82 (2%)
Query: 1058 AIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTY 1117
A AG +ATL+C V + ++TW K+ + + M + L +++ D G Y
Sbjct: 902 AEAGASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEY 960
Query: 1118 CCKAVNDLGTVEIECKLEVKVI 1139
C+A + ++ K E KV+
Sbjct: 961 SCEAGGQRLSFHLDVK-EPKVV 981
Score = 32.0 bits (71), Expect = 3.4
Identities = 17/62 (27%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 1060 AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCC 1119
AG +ATL+C V + ++TW K+ + + R+ + + L +++ D G Y C
Sbjct: 1272 AGASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTC 1330
Query: 1120 KA 1121
+A
Sbjct: 1331 EA 1332
Score = 31.6 bits (70), Expect = 4.5
Identities = 18/64 (28%), Positives = 32/64 (50%), Gaps = 1/64 (1%)
Query: 1058 AIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTY 1117
A AG +ATL+C V + ++TW K+ + + R+ + L +++ D G Y
Sbjct: 1638 AEAGASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQADAGEY 1696
Query: 1118 CCKA 1121
C+A
Sbjct: 1697 SCEA 1700
Score = 31.6 bits (70), Expect = 4.5
Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 2/71 (2%)
Query: 1049 FTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRK 1108
FT+ L N A+ G A L C + + + W K + D RY + C L+I
Sbjct: 3452 FTEGLRNEEAVEGATAMLWCEL--SKVAPVEWRKGPENLRDGDRYILRQEGTRCELQICG 3509
Query: 1109 PSPYDGGTYCC 1119
+ D G Y C
Sbjct: 3510 LAMADAGEYLC 3520
Score = 30.8 bits (68), Expect = 7.7
Identities = 19/77 (24%), Positives = 36/77 (46%)
Query: 540 GNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHI 599
G+ LRLE ++ + +A W + + +G + + +L+I +R D+G Y
Sbjct: 4912 GDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLLITGLDRADAGCYTC 4971
Query: 600 NLKNEAGEAHASIKVKV 616
+ N+ G+ S V V
Sbjct: 4972 QVSNKFGQVTHSACVVV 4988
>gi|148833506 obscurin, cytoskeletal calmodulin and titin-interacting
RhoGEF isoform b [Homo sapiens]
Length = 7968
Score = 129 bits (323), Expect = 2e-29
Identities = 100/370 (27%), Positives = 164/370 (44%), Gaps = 19/370 (5%)
Query: 250 KSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRIL 309
K F K LD ++ G + E++DP+ V W K+G ++ PS KY F H R L
Sbjct: 2645 KPVVFLKALDDL-SAEERGTLALQCEVSDPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGL 2703
Query: 310 FINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDD 369
+++ D Y G E+ + V + + +TK+L+ GE EC +S +
Sbjct: 2704 VVHDVSPEDAGLYTCHVGSEETRARVRVHDLHVGITKRLKTMEVLEGESCSFECVLSHES 2763
Query: 370 AN--VKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLS 427
A+ W G+ + G SR++ +G+K+IL++ A +DA E G S A L
Sbjct: 2764 ASDPAMWTVGGKTV--GSSSRFQATRQGRKYILVVREAAPSDAGEVVFSVRGLTSKASLI 2821
Query: 428 VDLKPLKILTPLTDQTVNLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIH 486
V +P I+ PL DQ V G+++ L+CE+S P W K+ +++S + VV +G +
Sbjct: 2822 VRERPAAIIKPLEDQWVAPGEDVELRCELSRAGTPVHWLKDRKAIRKSQKYDVVCEGTMA 2881
Query: 487 KLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKII---LDGLDADNTVTVIAGNKL 543
LVI A +D G+Y +A T A +HV + L L + T + K
Sbjct: 2882 MLVIRGASLKDAGEYTCEVEASKST--ASLHVEEKANCFTEELTNLQVEEKGTAVFTCK- 2938
Query: 544 RLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKN 603
+ P W +G + SG+ + + L I E+ DS Y ++
Sbjct: 2939 ------TEHPAATVTWRKG-LLELRASGKHQPSQEGLTLRLTISALEKADSDTYTCDIGQ 2991
Query: 604 EAGEAHASIK 613
A ++
Sbjct: 2992 AQSRAQLLVQ 3001
Score = 127 bits (318), Expect = 8e-29
Identities = 99/387 (25%), Positives = 168/387 (43%), Gaps = 24/387 (6%)
Query: 243 RMRREEKKSAAFAK--ILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIF 300
R+R E K FAK + Q + G E+A + EV WYK+G+++ S+K
Sbjct: 880 RLRVSEPK-VVFAKEQLARRKLQAEAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVCM 938
Query: 301 EHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQL---EDTTAYCGE 357
E GC R L + D EY AG ++ S L V+EP ++ K + A G
Sbjct: 939 EATGCTRRLVVQQAGQADAGEYSCEAGGQRLSFHLDVKEPKVVFAKDQVAHSEVQAEAGA 998
Query: 358 RVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGK--KHILIIEGATKADAAEYSV 415
L CEV++ V W+K+G+++ S ++ VE K + L+++ A K DA +YS
Sbjct: 999 SATLSCEVAQAQTEVMWYKDGKKL----SSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSC 1054
Query: 416 MTTGGQSSAKLSVDLKPL---KILTPLTDQTVNLGKEICLKCEISE-NIPGKWTKNGLPV 471
G + S +L + + K + + G L CE+++ W K+G +
Sbjct: 1055 EARGQRVSFRLHITEPKMMFAKEQSVHNEVQAEAGASAMLSCEVAQAQTEVTWYKDGKKL 1114
Query: 472 QESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDA 531
S ++ + KG +LV+ A D G+Y V+ +H+ +P +
Sbjct: 1115 SSSSKVGMEVKGCTRRLVLPQAGKADAGEYSCEAGGQRVSF--HLHITEPKGVFAKEQSV 1172
Query: 532 DNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAER 591
N V AG L ++ +P + W + K + S ++R E + LV+ +
Sbjct: 1173 HNEVQAEAGTTAMLSCEVA-QPQTEVTWYKDGKK-LSSSSKVRMEVKGCTRRLVVQQVGK 1230
Query: 592 DDSGVYHINLKNEAGEAHASIKVKVVD 618
D+G Y EAG S ++ + +
Sbjct: 1231 ADAGEYSC----EAGGQRVSFQLHITE 1253
Score = 123 bits (308), Expect = 1e-27
Identities = 199/885 (22%), Positives = 335/885 (37%), Gaps = 104/885 (11%)
Query: 105 KAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTG 164
K GK L + T + + +A AG Y CE + SF L+V E
Sbjct: 925 KDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEAGGQ----RLSFHLDVKE--- 977
Query: 165 TTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLKN-------A 217
P + E Q +AG S L + Q E + L + A
Sbjct: 978 --PKVVFAKDQVAHSEVQAEAGA---SATLSCEVAQAQTEVMWYKDGKKLSSSLKVHVEA 1032
Query: 218 KPSEYEKIAFQYGITDL-------RGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRV 270
K + Q G TD RG + E K A + + Q + G
Sbjct: 1033 KGCRRRLVVQQAGKTDAGDYSCEARGQRVSFRLHITEPKMMFAKEQSVHNEVQAEAGASA 1092
Query: 271 RFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEK 330
E+A + EV WYK+G+++ S+K E KGC R L + D EY AG ++
Sbjct: 1093 MLSCEVAQAQTEVTWYKDGKKLSSSSKVGMEVKGCTRRLVLPQAGKADAGEYSCEAGGQR 1152
Query: 331 CSTELFVREPPIMVTKQL---EDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKS 387
S L + EP + K+ + A G L CEV++ V W+K+G+++ S
Sbjct: 1153 VSFHLHITEPKGVFAKEQSVHNEVQAEAGTTAMLSCEVAQPQTEVTWYKDGKKL--SSSS 1210
Query: 388 RYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSV-DLKPLKILTPLTDQTV-- 444
+ R+ V+G L+++ KADA EYS G + S +L + + K + L V
Sbjct: 1211 KVRMEVKGCTRRLVVQQVGKADAGEYSCEAGGQRVSFQLHITEPKAVFAKEQLVHNEVRT 1270
Query: 445 NLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF 503
G L CE+++ W K+G + S ++++ G + +LV+ A D G+Y
Sbjct: 1271 EAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTC 1330
Query: 504 APDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGD 563
+A L + V +P + A V AG L ++ + G
Sbjct: 1331 --EAGGQRLSFHLDVSEPKAVFAKEQLAHRKVQAEAGAIATLSCEVAQAQTEVTWYKDGK 1388
Query: 564 KAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPP 623
K + S ++R E+ + LV+ A + D+G Y EAG S + V +
Sbjct: 1389 K--LSSSSKVRMEAVGCTRRLVVQQACQADTGEYSC----EAGGQRLSFSLDVAE----- 1437
Query: 624 VAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKK 683
P V + ++ E A G S L + + + + W + K+ +F K
Sbjct: 1438 --PKVVFAKEQ--PVHREVQAQAGASTTLSCEVAQAQTE-VMWYKDG----KKLSFSSKV 1488
Query: 684 MIEGVAYEVRIF---AVNAIG--ISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRW 738
+E V R+ A A+ S + R L V P + + V
Sbjct: 1489 RMEAVGCTRRLVVQQAGQAVAGEYSCEAGSQRLSFHLHVAEPKAVFAKEQPASREVQA-- 1546
Query: 739 RPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTIT 798
E TSA S E +A ++ W K L +K +
Sbjct: 1547 --------------------EAGTSATLSCEVAQAQTEV---TWYKDGKKLSSSSKVRME 1583
Query: 799 GLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRV----G 854
+ ++ V+ AG K Q + + PK+ + +Q R V G
Sbjct: 1584 AVGCTRRLVVQEAGQADAGEYSCKAGDQRLSFHLHVAEPKVVFAK--EQPAHREVQAEAG 1641
Query: 855 EAVNLVIPFQGKPRPELTWKKDGAEI-DKNQINIRNSETDTIIFIRKAERSHSGKYDLQV 913
+ L + + E+TW KDG ++ +++ + + +++A ++ +G+Y +
Sbjct: 1642 ASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQADAGEYSCEA 1700
Query: 914 ---KVDKFVETASIDIQIIDRP--GPPQIVKIEDVWGENVALTWT 953
++ + A ++ QI +RP P +VK E++ LT T
Sbjct: 1701 GGQRLSFRLHVAELEPQISERPCRREPLVVKEH----EDIILTAT 1741
Score = 108 bits (270), Expect = 3e-23
Identities = 88/353 (24%), Positives = 153/353 (43%), Gaps = 14/353 (3%)
Query: 265 DKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYV 324
++GG F ++ + V W+++G ++PS K+ G L I++ + D + V
Sbjct: 1911 EEGGEATFQCVVSPSDVAVVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITV 1970
Query: 325 TAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPG 384
A S L VRE P++ K+LE T V LE E++ ++W +N + PG
Sbjct: 1971 EAEGASSSAALRVREAPVLFKKKLEPQTVEERSSVTLEVELTRPWPELRWTRNATALAPG 2030
Query: 385 PKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTV 444
I EG +H L++ AD + T ++ AKL+V+++ ++++ L
Sbjct: 2031 --KNVEIHAEGARHRLVLHNVGFADRGFFGCETPDDKTQAKLTVEMRQVRLVRGLQAVEA 2088
Query: 445 NLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF 503
++ ++S ++ G WT++GL Q+ + +G +H L ++ ED G VF
Sbjct: 2089 REQGTATMEVQLSHADVDGSWTRDGLRFQQGPTCHLAVRGPMHTLTLSGLRPEDSGLMVF 2148
Query: 504 APDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGD 563
A V A++ V + P L V K+ LE +S P W + D
Sbjct: 2149 --KAEGVHTSARLVVTELPVSFSRPL---QDVVTTEKEKVTLECELS-RPNVDVRWLK-D 2201
Query: 564 KAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKV 616
+ + + +L I E D GVY +A +A +S VKV
Sbjct: 2202 GVELRAGKTMAIAAQGACRSLTIYRCEFADQGVYVC----DAHDAQSSASVKV 2250
Score = 107 bits (268), Expect = 5e-23
Identities = 74/265 (27%), Positives = 120/265 (45%), Gaps = 10/265 (3%)
Query: 263 QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 322
Q + G E+A + EV WYK+G+++ S+K E GC R L + D EY
Sbjct: 1545 QAEAGTSATLSCEVAQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEY 1604
Query: 323 YVTAGDEKCSTELFVREPPIMVTKQL---EDTTAYCGERVELECEVSEDDANVKWFKNGE 379
AGD++ S L V EP ++ K+ + A G L CEV++ V W+K+G+
Sbjct: 1605 SCKAGDQRLSFHLHVAEPKVVFAKEQPAHREVQAEAGASATLSCEVAQAQTEVTWYKDGK 1664
Query: 380 EIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSV-DLKPLKILTP 438
++ S+ R+ G L+++ A +ADA EYS G + S +L V +L+P P
Sbjct: 1665 KL--SSSSKVRVEAVGCTRRLVVQQAGQADAGEYSCEAGGQRLSFRLHVAELEPQISERP 1722
Query: 439 LTDQ--TVNLGKEICLKCEISENIPG--KWTKNGLPVQESDRLKVVHKGRIHKLVIANAL 494
+ V ++I L ++ W K+G+ ++ S R + +G H L + A
Sbjct: 1723 CRREPLVVKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQ 1782
Query: 495 TEDEGDYVFAPDAYNVTLPAKVHVI 519
D Y A P +V +
Sbjct: 1783 VLDSAIYSCRVGAEGQDFPVQVEEV 1807
Score = 106 bits (265), Expect = 1e-22
Identities = 88/339 (25%), Positives = 149/339 (43%), Gaps = 14/339 (4%)
Query: 283 VKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPI 342
V+W+K + +R ++ G + L I D EY G E+ S L VR P
Sbjct: 3655 VEWWKGHETLRDGDRHSLRQDGARCELQIRGLVAEDAGEYLCMCGKERTSAMLTVRAMPS 3714
Query: 343 MVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILII 402
+ L + A G+ L CE+S+ A V+W K E + G R+ +R +G + L I
Sbjct: 3715 KFIEGLRNEEATEGDTATLWCELSKA-APVEWRKGHETLRDG--DRHSLRQDGSRCELQI 3771
Query: 403 EGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPG 462
G DA EYS + ++SA L+V P + + + +Q G L+CE+S+ P
Sbjct: 3772 RGLAVVDAGEYSCVCGQERTSATLTVRALPARFIEDVKNQEAREGATAVLQCELSKAAPV 3831
Query: 463 KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY--VFAPDAYNVTLPAKVHVID 520
+W K ++ DR + G +L I D G+Y V + + TL +
Sbjct: 3832 EWRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSCVCGQERTSATLTVRA---- 3887
Query: 521 PPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPD 580
P + + L ++ G+ L+ +S EP +WS+G ++ +GR
Sbjct: 3888 PQPVFREPL---QSLQAEEGSTATLQCELS-EPTATVVWSKGGLQ-LQANGRREPRLQGC 3942
Query: 581 SSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDF 619
++ LV+ +R+D+G Y ++A A ++ V F
Sbjct: 3943 TAELVLQDLQREDTGEYTCTCGSQATSATLTVTAAPVRF 3981
Score = 106 bits (264), Expect = 1e-22
Identities = 78/287 (27%), Positives = 128/287 (44%), Gaps = 10/287 (3%)
Query: 283 VKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPI 342
V+W K + +R +YI +G + L I M D EY G E+ S L +R P
Sbjct: 3479 VEWRKGPENLRDGDRYILRQEGTRCELQICGLAMADAGEYLCVCGQERTSATLTIRALPA 3538
Query: 343 MVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILII 402
+ +++ A G L+CE++ A V+W K E + G RY +R +G K L I
Sbjct: 3539 RFIEDVKNQEAREGATAVLQCELNSA-APVEWRKGSETLRDG--DRYSLRQDGTKCELQI 3595
Query: 403 EGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPG 462
G AD EYS + ++SA L+V P+K L ++ G L+CE+S+ P
Sbjct: 3596 RGLAMADTGEYSCVCGQERTSAMLTVRALPIKFTEGLRNEEATEGATAVLRCELSKMAPV 3655
Query: 463 KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPP 522
+W K +++ DR + G +L I + ED G+Y+ + V + P
Sbjct: 3656 EWWKGHETLRDGDRHSLRQDGARCELQIRGLVAEDAGEYLCMCGKERTSAMLTVRAM--P 3713
Query: 523 KIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEG 569
++GL + G+ L +S P + W +G + + +G
Sbjct: 3714 SKFIEGLRNEEAT---EGDTATLWCELSKAAPVE--WRKGHETLRDG 3755
Score = 105 bits (263), Expect = 2e-22
Identities = 95/351 (27%), Positives = 155/351 (44%), Gaps = 14/351 (3%)
Query: 268 GRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAG 327
G F EL+ EV+W NG + + + HKG + L + + Q D ++
Sbjct: 2573 GWASFSCELSHEDEEVEWSLNGMPLYNDSFHEISHKGRRHTLVLKSIQRADAGIVRASSL 2632
Query: 328 DEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKS 387
S L VR P++ K L+D +A + L+CEVS+ +A+V W K+G ++ GP
Sbjct: 2633 KVSTSARLEVRVKPVVFLKALDDLSAEERGTLALQCEVSDPEAHVVWRKDGVQL--GPSD 2690
Query: 388 RYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLG 447
+Y L++ + DA Y+ ++ A++ V + I L V G
Sbjct: 2691 KYDFLHTAGTRGLVVHDVSPEDAGLYTCHVGSEETRARVRVHDLHVGITKRLKTMEVLEG 2750
Query: 448 KEICLKCEISE---NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFA 504
+ +C +S + P WT G V S R + +GR + LV+ A D G+ VF+
Sbjct: 2751 ESCSFECVLSHESASDPAMWTVGGKTVGSSSRFQATRQGRKYILVVREAAPSDAGEVVFS 2810
Query: 505 PDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDK 564
+T A + V + P I+ L+ D V +LR E+ +G P W + K
Sbjct: 2811 --VRGLTSKASLIVRERPAAIIKPLE-DQWVAPGEDVELRCELSRAGTP---VHWLKDRK 2864
Query: 565 AIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVK 615
AI + S + + LVI A D+G Y + EA ++ AS+ V+
Sbjct: 2865 AIRK-SQKYDVVCEGTMAMLVIRGASLKDAGEYTCEV--EASKSTASLHVE 2912
Score = 105 bits (262), Expect = 2e-22
Identities = 71/245 (28%), Positives = 111/245 (45%), Gaps = 7/245 (2%)
Query: 265 DKGGRVRFVVELADPK--LEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 322
+ G R +L+D + V+W K G E+ KY +G R L I+ + D EY
Sbjct: 4080 ETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATRELLIHQLEAKDTGEY 4139
Query: 323 YVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDAN-VKWFKNGEEI 381
G +K + L V EP + + + L D E VE CEVS A V+W G +
Sbjct: 4140 ACVTGGQKTAASLRVTEPEVTIVRGLVDAEVTADEDVEFSCEVSRAGATGVQWCLQGLPL 4199
Query: 382 IPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTD 441
+ +R +G+ H L ++G T DA S SSA+L+V + IL PL D
Sbjct: 4200 QSNEVTEVAVR-DGRIHTLRLKGVTPEDAGTVSFHLGNHASSAQLTVRAPEVTILEPLQD 4258
Query: 442 QTVNLGKEICLKCEIS--ENIPGKWTKNGLPVQESDRLKV-VHKGRIHKLVIANALTEDE 498
++ G++ +C +S +W G+P+Q ++ + V +G +H L + ED
Sbjct: 4259 VQLSEGQDASFQCRLSRASGQEARWALGGVPLQANEMNDITVEQGTLHLLTLHKVTLEDA 4318
Query: 499 GDYVF 503
G F
Sbjct: 4319 GTVSF 4323
Score = 105 bits (261), Expect = 3e-22
Identities = 90/364 (24%), Positives = 150/364 (41%), Gaps = 12/364 (3%)
Query: 263 QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 322
Q G E+A + EV WYK+G+++ S+K E GC R L + EY
Sbjct: 1453 QAQAGASTTLSCEVAQAQTEVMWYKDGKKLSFSSKVRMEAVGCTRRLVVQQAGQAVAGEY 1512
Query: 323 YVTAGDEKCSTELFVREPPIMVTKQ---LEDTTAYCGERVELECEVSEDDANVKWFKNGE 379
AG ++ S L V EP + K+ + A G L CEV++ V W+K+G+
Sbjct: 1513 SCEAGSQRLSFHLHVAEPKAVFAKEQPASREVQAEAGTSATLSCEVAQAQTEVTWYKDGK 1572
Query: 380 EIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPL---KIL 436
++ S+ R+ G L+++ A +ADA EYS + S L V + K
Sbjct: 1573 KL--SSSSKVRMEAVGCTRRLVVQEAGQADAGEYSCKAGDQRLSFHLHVAEPKVVFAKEQ 1630
Query: 437 TPLTDQTVNLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALT 495
+ G L CE+++ W K+G + S +++V G +LV+ A
Sbjct: 1631 PAHREVQAEAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQ 1690
Query: 496 EDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPP 555
D G+Y + +A L ++HV + I + + V + L ++
Sbjct: 1691 ADAGEY--SCEAGGQRLSFRLHVAELEPQISERPCRREPLVVKEHEDIILTATLATPSAA 1748
Query: 556 KAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVK 615
W + D + S R T S D+ TL + A+ DS +Y + E + ++
Sbjct: 1749 TVTWLK-DGVEIRRSKRHETASQGDTHTLTVHGAQVLDSAIYSCRVGAEGQDFPVQVEEV 1807
Query: 616 VVDF 619
F
Sbjct: 1808 AAKF 1811
Score = 105 bits (261), Expect = 3e-22
Identities = 89/366 (24%), Positives = 152/366 (41%), Gaps = 16/366 (4%)
Query: 263 QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 322
Q ++G EL++P V W K G +++ + + +GC L + + Q D EY
Sbjct: 3900 QAEEGSTATLQCELSEPTATVVWSKGGLQLQANGRREPRLQGCTAELVLQDLQREDTGEY 3959
Query: 323 YVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEII 382
T G + S L V P+ ++L+ G L CE+S A+V+W K ++
Sbjct: 3960 TCTCGSQATSATLTVTAAPVRFLRELQHQEVDEGGTAHLCCELSRAGASVEWRKGSLQLF 4019
Query: 383 PGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQ 442
P K Y++ +G L++ G + DA +Y+ T QS A LSV + K T L
Sbjct: 4020 PCAK--YQMVQDGAAAELLVRGVEQEDAGDYTCDTGHTQSMASLSVRVPRPKFKTRLQSL 4077
Query: 443 TVNLGKEICLKCEISENIPG---KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEG 499
G L C++S+ G +W K G+ + + ++ +G +L+I +D G
Sbjct: 4078 EQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATRELLIHQLEAKDTG 4137
Query: 500 DYVFAPDAYNVTLPAKVHVIDPPKIILDGL-DADNTVTVIAGNKLRLEIPISGEPPPKAM 558
+Y A + V +P I+ GL DA+ V A + +S
Sbjct: 4138 EYACVTGGQKTA--ASLRVTEPEVTIVRGLVDAE----VTADEDVEFSCEVSRAGATGVQ 4191
Query: 559 WSRGDKAIMEGSGRIRTESYPDS--STLVIDIAERDDSGVYHINLKNEAGEAHASIKVKV 616
W + + S + + D TL + +D+G +L N A A +++
Sbjct: 4192 WCL--QGLPLQSNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSFHLGNHASSAQLTVRAPE 4249
Query: 617 VDFPDP 622
V +P
Sbjct: 4250 VTILEP 4255
Score = 104 bits (259), Expect = 5e-22
Identities = 89/333 (26%), Positives = 142/333 (42%), Gaps = 10/333 (3%)
Query: 283 VKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPI 342
V+WYK+ + PS K+ +G L I D Y AG STE+ V +
Sbjct: 2499 VQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRCQAGSAHSSTEVTVEAREV 2558
Query: 343 MVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILII 402
VT L+D A CE+S +D V+W NG + S + I +G++H L++
Sbjct: 2559 TVTGPLQDAEATEEGWASFSCELSHEDEEVEWSLNGMPLY--NDSFHEISHKGRRHTLVL 2616
Query: 403 EGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISE-NIP 461
+ +ADA + +SA+L V +KP+ L L D + + L+CE+S+
Sbjct: 2617 KSIQRADAGIVRASSLKVSTSARLEVRVKPVVFLKALDDLSAEERGTLALQCEVSDPEAH 2676
Query: 462 GKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDP 521
W K+G+ + SD+ +H LV+ + ED G Y + A+V V D
Sbjct: 2677 VVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYTCHVGSEETR--ARVRVHDL 2734
Query: 522 PKIILDGLDADNTVTVIAGNKLRLEIPISGE-PPPKAMWSRGDKAIMEGSGRIRTESYPD 580
I L T+ V+ G E +S E AMW+ G K + S R +
Sbjct: 2735 HVGITKRL---KTMEVLEGESCSFECVLSHESASDPAMWTVGGKTV-GSSSRFQATRQGR 2790
Query: 581 SSTLVIDIAERDDSGVYHINLKNEAGEAHASIK 613
LV+ A D+G +++ +A ++
Sbjct: 2791 KYILVVREAAPSDAGEVVFSVRGLTSKASLIVR 2823
Score = 102 bits (253), Expect = 3e-21
Identities = 86/314 (27%), Positives = 131/314 (41%), Gaps = 13/314 (4%)
Query: 263 QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 322
+V +GG L+ VKW +RP KY +G L + N + D Y
Sbjct: 3195 EVLEGGAATLRCVLSSVAAPVKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQDSGRY 3254
Query: 323 YVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEII 382
+ GD+ S L V P +L + A G L CE+S+ A V+W K E +
Sbjct: 3255 SCSFGDQTTSATLTVTALPAQFIGKLRNKEATEGATATLRCELSKA-APVEWRKGSETLR 3313
Query: 383 PGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQ 442
G RY +R +G L I G DAAEYS + ++SA L++ P + L Q
Sbjct: 3314 DG--DRYCLRQDGAMCELQIRGLAMVDAAEYSCVCGEERTSASLTIRPMPAHFIGRLRHQ 3371
Query: 443 TVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY- 501
G L+CE+S+ P +W K +++ DR + G + +L I D G+Y
Sbjct: 3372 ESIEGATATLRCELSKAAPVEWRKGRESLRDGDRHSLRQDGAVCELQICGLAVADAGEYS 3431
Query: 502 -VFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTV---TVIAGNKLRLEIPISGEPPPKA 557
V + + TL K P +GL + V T + +L P+ P+
Sbjct: 3432 CVCGEERTSATLTVKA----LPAKFTEGLRNEEAVEGATAMLWCELSKVAPVEWRKGPEN 3487
Query: 558 MWSRGDKAIMEGSG 571
+ GD+ I+ G
Sbjct: 3488 L-RDGDRYILRQEG 3500
Score = 99.8 bits (247), Expect = 1e-20
Identities = 99/402 (24%), Positives = 162/402 (40%), Gaps = 53/402 (13%)
Query: 253 AFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFIN 312
+F++ L +K +V EL+ P ++V+W K+G E+R +G R L I
Sbjct: 2167 SFSRPLQDVVTTEKE-KVTLECELSRPNVDVRWLKDGVELRAGKTMAIAAQGACRSLTIY 2225
Query: 313 NCQMTDDSEYYVTAGDEKCST-----------------------------------ELFV 337
C+ D Y A D + S +L V
Sbjct: 2226 RCEFADQGVYVCDAHDAQSSASVKVQGRTYTLIYRRVLAEDAGEIQFVAENAESRAQLRV 2285
Query: 338 REPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKK 397
+E P+ + + L D A R LEC+VS A V+WFK +E+ PGPK Y + +G
Sbjct: 2286 KELPVTLVRPLRDKIAMEKHRGVLECQVSRASAQVRWFKGSQELQPGPK--YELVSDGLY 2343
Query: 398 HILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCE-- 455
LII D Y+ ++SA+ V+ + + I+ L D TV +CE
Sbjct: 2344 RKLIISDVHAEDEDTYTCDAGDVKTSAQFFVEEQSITIVRGLQDVTVMEPAPAWFECETS 2403
Query: 456 ISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAK 515
I P KW +Q + + +G +H+L++ + G F + A+
Sbjct: 2404 IPSVRPPKWLLGKTVLQAGGNVGLEQEGTVHRLMLRRTCSTMTGPVHFTVGKSRSS--AR 2461
Query: 516 VHVIDPPKIILDGLDADNTVTVIAGNKLR-LEIPISGEPPPKAMWSRGDKAIMEGSGRIR 574
+ V D P ++ L+ G +L+ + + P PKA+ D + S + +
Sbjct: 2462 LVVSDIPVVLTRPLEPK------TGRELQSVVLSCDFRPAPKAVQWYKDDTPLSPSEKFK 2515
Query: 575 TESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKV 616
+ L I D+GVY + +AG AH+S +V V
Sbjct: 2516 MSLEGQMAELRILRLMPADAGVY----RCQAGSAHSSTEVTV 2553
Score = 96.3 bits (238), Expect = 1e-19
Identities = 63/220 (28%), Positives = 99/220 (45%), Gaps = 3/220 (1%)
Query: 283 VKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPI 342
V+W K + +R +Y G + L I+ + D EY G E+ S L VR P
Sbjct: 3831 VEWRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSCVCGQERTSATLTVRAPQP 3890
Query: 343 MVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILII 402
+ + L+ A G L+CE+SE A V W K G ++ R R++G L++
Sbjct: 3891 VFREPLQSLQAEEGSTATLQCELSEPTATVVWSKGGLQL--QANGRREPRLQGCTAELVL 3948
Query: 403 EGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISE-NIP 461
+ + D EY+ +SA L+V P++ L L Q V+ G L CE+S
Sbjct: 3949 QDLQREDTGEYTCTCGSQATSATLTVTAAPVRFLRELQHQEVDEGGTAHLCCELSRAGAS 4008
Query: 462 GKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 501
+W K L + + ++V G +L++ ED GDY
Sbjct: 4009 VEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDY 4048
Score = 95.1 bits (235), Expect = 3e-19
Identities = 68/263 (25%), Positives = 113/263 (42%), Gaps = 3/263 (1%)
Query: 239 KRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKY 298
+R R +K + F++ L A + +G + V E + + V W K+G+ +R S +
Sbjct: 3083 QRASAALRVTEKPSVFSRELTDA-TITEGEDLTLVCETSTCDIPVCWTKDGKTLRGSARC 3141
Query: 299 IFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGER 358
H+G + L I + D Y AG S+ + V P+ + L+D G
Sbjct: 3142 QLSHEGHRAQLLITGATLQDSGRYKCEAGGACSSSIVRVHARPVRFQEALKDLEVLEGGA 3201
Query: 359 VELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTT 418
L C +S A VKW + PG K Y +R EG L++ D+ YS
Sbjct: 3202 ATLRCVLSSVAAPVKWCYGNNVLRPGDK--YSLRQEGAMLELVVRNLRPQDSGRYSCSFG 3259
Query: 419 GGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLK 478
+SA L+V P + + L ++ G L+CE+S+ P +W K +++ DR
Sbjct: 3260 DQTTSATLTVTALPAQFIGKLRNKEATEGATATLRCELSKAAPVEWRKGSETLRDGDRYC 3319
Query: 479 VVHKGRIHKLVIANALTEDEGDY 501
+ G + +L I D +Y
Sbjct: 3320 LRQDGAMCELQIRGLAMVDAAEY 3342
Score = 94.7 bits (234), Expect = 4e-19
Identities = 70/254 (27%), Positives = 110/254 (43%), Gaps = 5/254 (1%)
Query: 248 EKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQR 307
E+ +A F ++L+P + GG V EL+ EV W ++R ++ +G R
Sbjct: 1805 EEVAAKFCRLLEPVCG-ELGGTVTLACELSPACAEVVWRCGNTQLRVGKRFQMVAEGPVR 1863
Query: 308 ILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIM-VTKQLEDTTAYCGERVELECEVS 366
L + + D EY + D+ S +L V P ++ L A G +C VS
Sbjct: 1864 SLTVLGLRAEDAGEYVCESRDDHTSAQLTVSVPRVVKFMSGLSTVVAEEGGEATFQCVVS 1923
Query: 367 EDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKL 426
D V WF++G + P K + I G H L I DA + +V G SSA L
Sbjct: 1924 PSDVAVVWFRDGALLQPSEK--FAISQSGASHSLTISDLVLEDAGQITVEAEGASSSAAL 1981
Query: 427 SVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPG-KWTKNGLPVQESDRLKVVHKGRI 485
V P+ L QTV + L+ E++ P +WT+N + +++ +G
Sbjct: 1982 RVREAPVLFKKKLEPQTVEERSSVTLEVELTRPWPELRWTRNATALAPGKNVEIHAEGAR 2041
Query: 486 HKLVIANALTEDEG 499
H+LV+ N D G
Sbjct: 2042 HRLVLHNVGFADRG 2055
Score = 94.4 bits (233), Expect = 6e-19
Identities = 84/341 (24%), Positives = 136/341 (39%), Gaps = 15/341 (4%)
Query: 283 VKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPI 342
V+W K + +R +Y G L I M D +EY G+E+ S L +R P
Sbjct: 3303 VEWRKGSETLRDGDRYCLRQDGAMCELQIRGLAMVDAAEYSCVCGEERTSASLTIRPMPA 3362
Query: 343 MVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILII 402
+L + G L CE+S+ A V+W K E + G R+ +R +G L I
Sbjct: 3363 HFIGRLRHQESIEGATATLRCELSKA-APVEWRKGRESLRDG--DRHSLRQDGAVCELQI 3419
Query: 403 EGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPG 462
G ADA EYS + ++SA L+V P K L ++ G L CE+S+ P
Sbjct: 3420 CGLAVADAGEYSCVCGEERTSATLTVKALPAKFTEGLRNEEAVEGATAMLWCELSKVAPV 3479
Query: 463 KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPP 522
+W K +++ DR + +G +L I D G+Y+ + + + P
Sbjct: 3480 EWRKGPENLRDGDRYILRQEGTRCELQICGLAMADAGEYLCVCGQERTSATLTIRAL-PA 3538
Query: 523 KIILD--GLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPD 580
+ I D +A T + +L P+ W +G + + +G R
Sbjct: 3539 RFIEDVKNQEAREGATAVLQCELNSAAPVE--------WRKGSETLRDGD-RYSLRQDGT 3589
Query: 581 SSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPD 621
L I D+G Y E A +++ + F +
Sbjct: 3590 KCELQIRGLAMADTGEYSCVCGQERTSAMLTVRALPIKFTE 3630
Score = 93.2 bits (230), Expect = 1e-18
Identities = 80/337 (23%), Positives = 146/337 (43%), Gaps = 11/337 (3%)
Query: 283 VKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPI 342
V W K+G EIR S ++ +G L ++ Q+ D + Y G E + V E
Sbjct: 1750 VTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQVLDSAIYSCRVGAEGQDFPVQVEEVAA 1809
Query: 343 MVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILII 402
+ LE G V L CE+S A V W ++ G R+++ EG L +
Sbjct: 1810 KFCRLLEPVCGELGGTVTLACELSPACAEVVWRCGNTQLRVG--KRFQMVAEGPVRSLTV 1867
Query: 403 EGATKADAAEYSVMTTGGQSSAKLSVDL-KPLKILTPLTDQTVNLGKEICLKCEIS-ENI 460
G DA EY + +SA+L+V + + +K ++ L+ G E +C +S ++
Sbjct: 1868 LGLRAEDAGEYVCESRDDHTSAQLTVSVPRVVKFMSGLSTVVAEEGGEATFQCVVSPSDV 1927
Query: 461 PGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVID 520
W ++G +Q S++ + G H L I++ + ED G +A + A + V +
Sbjct: 1928 AVVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQ--ITVEAEGASSSAALRVRE 1985
Query: 521 PPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPD 580
P + L+ TV + + LE+ ++ P P+ W+R A+ G + +
Sbjct: 1986 APVLFKKKLEPQ---TVEERSSVTLEVELT-RPWPELRWTRNATALAPGK-NVEIHAEGA 2040
Query: 581 SSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVV 617
LV+ D G + ++ +A +++++ V
Sbjct: 2041 RHRLVLHNVGFADRGFFGCETPDDKTQAKLTVEMRQV 2077
Score = 90.9 bits (224), Expect = 6e-18
Identities = 67/274 (24%), Positives = 115/274 (41%), Gaps = 6/274 (2%)
Query: 246 REEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGC 305
R + F K L+P V++ V VEL P E++W +N + P +G
Sbjct: 1982 RVREAPVLFKKKLEPQ-TVEERSSVTLEVELTRPWPELRWTRNATALAPGKNVEIHAEGA 2040
Query: 306 QRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEV 365
+ L ++N D + D+K +L V + + + L+ A +E ++
Sbjct: 2041 RHRLVLHNVGFADRGFFGCETPDDKTQAKLTVEMRQVRLVRGLQAVEAREQGTATMEVQL 2100
Query: 366 SEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAK 425
S D + W ++G GP +R G H L + G D+ G +SA+
Sbjct: 2101 SHADVDGSWTRDGLRFQQGPTCHLAVR--GPMHTLTLSGLRPEDSGLMVFKAEGVHTSAR 2158
Query: 426 LSVDLKPLKILTPLTDQTVNLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGR 484
L V P+ PL D +++ L+CE+S N+ +W K+G+ ++ + + +G
Sbjct: 2159 LVVTELPVSFSRPLQDVVTTEKEKVTLECELSRPNVDVRWLKDGVELRAGKTMAIAAQGA 2218
Query: 485 IHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHV 518
L I D+G YV DA++ A V V
Sbjct: 2219 CRSLTIYRCEFADQGVYVC--DAHDAQSSASVKV 2250
Score = 90.9 bits (224), Expect = 6e-18
Identities = 66/241 (27%), Positives = 108/241 (44%), Gaps = 5/241 (2%)
Query: 264 VDKGGRVRFVVELADPKLE-VKWYKNGQEIRPST-KYIFEHKGCQRILFINNCQMTDDSE 321
V +G F ++ E V W+ + + + I G +L + + D
Sbjct: 3016 VQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQPGGYHVLTLRQLALKDSGT 3075
Query: 322 YYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEI 381
Y AGD++ S L V E P + +++L D T GE + L CE S D V W K+G+ +
Sbjct: 3076 IYFEAGDQRASAALRVTEKPSVFSRELTDATITEGEDLTLVCETSTCDIPVCWTKDGKTL 3135
Query: 382 IPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTD 441
+R ++ EG + L+I GAT D+ Y G SS+ + V +P++ L D
Sbjct: 3136 --RGSARCQLSHEGHRAQLLITGATLQDSGRYKCEAGGACSSSIVRVHARPVRFQEALKD 3193
Query: 442 QTVNLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGD 500
V G L+C +S P KW ++ D+ + +G + +LV+ N +D G
Sbjct: 3194 LEVLEGGAATLRCVLSSVAAPVKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQDSGR 3253
Query: 501 Y 501
Y
Sbjct: 3254 Y 3254
Score = 88.2 bits (217), Expect = 4e-17
Identities = 88/374 (23%), Positives = 146/374 (39%), Gaps = 11/374 (2%)
Query: 248 EKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQR 307
E+K+ F + L QV++ G F + P V W K E+R S K+ +G
Sbjct: 2912 EEKANCFTEELTNL-QVEEKGTAVFTCKTEHPAATVTWRKGLLELRASGKHQPSQEGLTL 2970
Query: 308 ILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSE 367
L I+ + D Y G + +L V+ + + + LED G C +S
Sbjct: 2971 RLTISALEKADSDTYTCDIGQAQSRAQLLVQGRRVHIIEDLEDVDVQEGSSATFRCRISP 3030
Query: 368 DDAN-VKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKL 426
+ V WF + + + + G H+L + D+ ++SA L
Sbjct: 3031 ANYEPVHWFLDKTPLHANELNEIDAQ-PGGYHVLTLRQLALKDSGTIYFEAGDQRASAAL 3089
Query: 427 SVDLKPLKILTPLTDQTVNLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRI 485
V KP LTD T+ G+++ L CE S +IP WTK+G ++ S R ++ H+G
Sbjct: 3090 RVTEKPSVFSRELTDATITEGEDLTLVCETSTCDIPVCWTKDGKTLRGSARCQLSHEGHR 3149
Query: 486 HKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRL 545
+L+I A +D G Y + +VH P + +A + V+ G L
Sbjct: 3150 AQLLITGATLQDSGRYKCEAGGACSSSIVRVHA-RPVRF----QEALKDLEVLEGGAATL 3204
Query: 546 EIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEA 605
+S P W G+ + G + LV+ DSG Y + ++
Sbjct: 3205 RCVLSSVAAP-VKWCYGNNVLRPGD-KYSLRQEGAMLELVVRNLRPQDSGRYSCSFGDQT 3262
Query: 606 GEAHASIKVKVVDF 619
A ++ F
Sbjct: 3263 TSATLTVTALPAQF 3276
Score = 85.9 bits (211), Expect = 2e-16
Identities = 87/375 (23%), Positives = 152/375 (40%), Gaps = 17/375 (4%)
Query: 261 AYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMT-DD 319
A Q +GG V F V+L +W+ +GQ ++ S+ Y + L I +
Sbjct: 621 AVQAVEGGEVTFSVDLTVASAG-EWFLDGQALKASSVYEIHCDRTRHTLTIREVPASLHG 679
Query: 320 SEYYVTAGDEKCSTELFVREPPIMVTKQ-----LEDTTAYCGERVELECEVSEDDANVKW 374
++ A + S + VR P + + + A E +L E+S+ A V W
Sbjct: 680 AQLKFVANGIESSIRMEVRAAPGLTANKPPAAAAREVLARLHEEAQLLAELSDQAAAVTW 739
Query: 375 FKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLK 434
K+G + PGPK Y ++ + +L++ + DA Y ++ GG+ + +LSV
Sbjct: 740 LKDGRTLSPGPK--YEVQASAGRRVLLVRDVARDDAGLYECVSRGGRIAYQLSVQGLARF 797
Query: 435 ILTPLTDQTVN--LGKEICLKCEISE-NIPGKWTKNGLPVQES-DRLKVVHKGRIHKLVI 490
+ + V+ G +CE SE ++ W K+G+ + S +R G H+LV
Sbjct: 798 LHKDMAGSCVDAVAGGPAQFECETSEAHVHVHWYKDGMELGHSGERFLQEDVGTRHRLVA 857
Query: 491 ANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPIS 550
A +DEG Y +V ++ V +P + A + AG L ++
Sbjct: 858 ATVTRQDEGTYSCRVGEDSVDF--RLRVSEPKVVFAKEQLARRKLQAEAGASATLSCEVA 915
Query: 551 GEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHA 610
+ G K + S ++ E+ + LV+ A + D+G Y + H
Sbjct: 916 QAQTEVTWYKDGKK--LSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEAGGQRLSFHL 973
Query: 611 SIKVKVVDFPDPPVA 625
+K V F VA
Sbjct: 974 DVKEPKVVFAKDQVA 988
Score = 84.7 bits (208), Expect = 4e-16
Identities = 88/394 (22%), Positives = 152/394 (38%), Gaps = 36/394 (9%)
Query: 327 GDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDAN-VKWFKNGEEIIPGP 385
G+ S +L VR P + + + L+D G+ +C +S +W G +
Sbjct: 4235 GNHASSAQLTVRAPEVTILEPLQDVQLSEGQDASFQCRLSRASGQEARWALGGVPLQANE 4294
Query: 386 KSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVN 445
+ + +G H+L + T DA S S A+L V K ++ L +
Sbjct: 4295 MNDITVE-QGTLHLLTLHKVTLEDAGTVSFHVGTCSSEAQLKVTAKNT-VVRGLENVEAL 4352
Query: 446 LGKEICLKCEIS--ENIPGKWTKNGLPVQESDRLKVV--HKGRIHKLVIANALTEDEGDY 501
G E +C++S E W + PV S+ +VV G H L++ N +D
Sbjct: 4353 EGGEALFECQLSQPEVAAHTWLLDDEPVHTSENAEVVFFENGLRHLLLLKNLRPQDSCRV 4412
Query: 502 VF-----APDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPIS-GEPPP 555
F A+ ++ +++P K V AG + +S P
Sbjct: 4413 TFLAGDMVTSAFLTVRGWRLEILEPLK----------NAAVRAGAQACFTCTLSEAVPVG 4462
Query: 556 KAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVK 615
+A W A+ + L++ A+ +G + +A AS ++
Sbjct: 4463 EASWYINGAAVQPDDSDWTVTADGSHHALLLRSAQPHHAGEVTFACR----DAVASARLT 4518
Query: 616 VVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCK 675
V+ PDPP V ++W P DGG + GY +E K+ + +W LC
Sbjct: 4519 VLGLPDPPEDAEVVARSSHTVTLSWAAPMSDGGGGLCGYRVEVKEGATGQWR-----LCH 4573
Query: 676 ETTFEPKKMIEGVA----YEVRIFAVNAIGISKP 705
E P+ +++G+A Y R+ AV +G +P
Sbjct: 4574 ELVPGPECVVDGLAPGETYRFRVAAVGPVGAGEP 4607
Score = 82.0 bits (201), Expect = 3e-15
Identities = 75/342 (21%), Positives = 139/342 (40%), Gaps = 15/342 (4%)
Query: 271 RFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEK 330
+ + EL+D V W K+G+ + P KY + +R+L + + D Y + +
Sbjct: 725 QLLAELSDQAAAVTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECVSRGGR 784
Query: 331 CSTELFVREPPIMVTKQLEDT--TAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSR 388
+ +L V+ + K + + A G + ECE SE +V W+K+G E + R
Sbjct: 785 IAYQLSVQGLARFLHKDMAGSCVDAVAGGPAQFECETSEAHVHVHWYKDGME-LGHSGER 843
Query: 389 YRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQT----- 443
+ G +H L+ T+ D YS G+ S + + K++
Sbjct: 844 FLQEDVGTRHRLVAATVTRQDEGTYSCRV--GEDSVDFRLRVSEPKVVFAKEQLARRKLQ 901
Query: 444 VNLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV 502
G L CE+++ W K+G + S ++ + G +LV+ A D G+Y
Sbjct: 902 AEAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEY- 960
Query: 503 FAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRG 562
+ +A L + V +P + A + V AG L ++ + + MW +
Sbjct: 961 -SCEAGGQRLSFHLDVKEPKVVFAKDQVAHSEVQAEAGASATLSCEVA-QAQTEVMWYKD 1018
Query: 563 DKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNE 604
K + S ++ E+ LV+ A + D+G Y + +
Sbjct: 1019 GKK-LSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEARGQ 1059
Score = 79.0 bits (193), Expect = 2e-14
Identities = 93/405 (22%), Positives = 153/405 (37%), Gaps = 59/405 (14%)
Query: 266 KGGRVRFVVELADPKLEVK-WYKNGQEIRPS--TKYIFEHKGCQRILFINNCQMTDDSEY 322
+GG F +L+ P++ W + + + S + +F G + +L + N + D
Sbjct: 4353 EGGEALFECQLSQPEVAAHTWLLDDEPVHTSENAEVVFFENGLRHLLLLKNLRPQDSCRV 4412
Query: 323 YVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSE--DDANVKWFKNGEE 380
AGD S L VR + + + L++ G + C +SE W+ NG
Sbjct: 4413 TFLAGDMVTSAFLTVRGWRLEILEPLKNAAVRAGAQACFTCTLSEAVPVGEASWYINGAA 4472
Query: 381 IIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSV----DLKPLKIL 436
+ P S + + +G H L++ A A E + +SA+L+V D +
Sbjct: 4473 VQPDD-SDWTVTADGSHHALLLRSAQPHHAGEVTFACRDAVASARLTVLGLPDPPEDAEV 4531
Query: 437 TPLTDQTVNL---------GKEIC-LKCEISENIPGKW------------TKNGLPVQES 474
+ TV L G +C + E+ E G+W +GL E+
Sbjct: 4532 VARSSHTVTLSWAAPMSDGGGGLCGYRVEVKEGATGQWRLCHELVPGPECVVDGLAPGET 4591
Query: 475 DRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNT 534
R +V G + V LP V + +PPK + A +
Sbjct: 4592 YRFRVAAVGPVGA-------------------GEPVHLPQTVRLAEPPKPVPPQPSAPES 4632
Query: 535 VTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDS 594
V AG + LE+ + E + +W +G + I G GR S LVI +D
Sbjct: 4633 RQVAAGEDVSLELEVVAE-AGEVIWHKGMERIQPG-GRFEVVSQGRQQMLVIKGFTAEDQ 4690
Query: 595 GVYHINL-KNEAGEAHASIKV-----KVVDFPDPPVAPTVTEVGD 633
G YH L + A A+ +V V + P P + P + GD
Sbjct: 4691 GEYHCGLAQGSICPAAATFQVALSPASVDEAPQPSLPPEAAQEGD 4735
Score = 75.9 bits (185), Expect = 2e-13
Identities = 76/288 (26%), Positives = 112/288 (38%), Gaps = 25/288 (8%)
Query: 232 TDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVE----------LADPKL 281
T +L L+R R + A PA G R V E +PK
Sbjct: 214 TSTAALLAHLQRRREAMRAEGA------PASPPSTGTRTCTVTEGKHARLSCYVTGEPKP 267
Query: 282 EVKWYKNGQEIRPSTKYI-FEHKGCQRILFINNCQMTDDSEYYVTA----GDEKCSTELF 336
E W K+GQ + +++ +E +L I C+ +D Y TA G S +
Sbjct: 268 ETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVV 327
Query: 337 VREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGK 396
VREP + K+L+D E CEV + WFK EE ++Y I EG
Sbjct: 328 VREPAVPFKKRLQDLEVREKESATFLCEVPQPSTEAAWFK--EETRLWASAKYGIEEEGT 385
Query: 397 KHILIIEGATKADAAEYSVMT-TGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCE 455
+ L + + D A Y T G ++ A+L+V L+ L T V C++
Sbjct: 386 ERRLTVRNVSADDDAVYICETPEGSRTVAELAVQGNLLRKLPRKTAVRVGDTAMFCVELA 445
Query: 456 ISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF 503
+ P W +N V R+ + +G H L I+ ED G F
Sbjct: 446 VPVG-PVHWLRNQEEVVAGGRVAISAEGTRHTLTISQCCLEDVGQVAF 492
Score = 67.0 bits (162), Expect = 1e-10
Identities = 60/217 (27%), Positives = 84/217 (38%), Gaps = 33/217 (15%)
Query: 239 KRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKY 298
KRL+ + EK+SA F + E+ P E W+K + S KY
Sbjct: 337 KRLQDLEVREKESATF------------------LCEVPQPSTEAAWFKEETRLWASAKY 378
Query: 299 IFEHKGCQRILFINNCQMTDDSEYYV-TAGDEKCSTELFV-----REPPIMVTKQLEDTT 352
E +G +R L + N DD+ Y T + EL V R+ P ++ DT
Sbjct: 379 GIEEEGTERRLTVRNVSADDDAVYICETPEGSRTVAELAVQGNLLRKLPRKTAVRVGDTA 438
Query: 353 AYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAE 412
+C VEL V V W +N EE++ G R I EG +H L I D +
Sbjct: 439 MFC---VELAVPVGP----VHWLRNQEEVVAG--GRVAISAEGTRHTLTISQCCLEDVGQ 489
Query: 413 YSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKE 449
+ M Q+S + V L P D V E
Sbjct: 490 VAFMAGDCQTSTQFCVSAPRKPPLQPPVDPVVKARME 526
Score = 64.3 bits (155), Expect = 6e-10
Identities = 72/308 (23%), Positives = 115/308 (37%), Gaps = 50/308 (16%)
Query: 356 GERVELECE-VSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYS 414
G+ L C+ V V W K+ + + G +R+R+ +G + L I D+ +Y
Sbjct: 24 GKDATLSCQIVGNPTPQVSWEKDQQPVAAG--ARFRLAQDGDLYRLTILDLALGDSGQYV 81
Query: 415 VMTTGGQSSAKLSVDLK-----------PLKILTPLTDQTVNLGKEICLKCEI--SENIP 461
A +V L+ P +L P T V G E +C + S
Sbjct: 82 CRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRP-TSIRVREGSEATFRCRVGGSPRPA 140
Query: 462 GKWTKNGLPVQESD--RLKVVHKGRIHKLVIANALTEDEGDY-VFAPDAYNVTLPAKVHV 518
W+K+G + E D R++V G L I A D G Y V A + A V
Sbjct: 141 VSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALV 200
Query: 519 IDPPK------------------------IILDGLDAD------NTVTVIAGNKLRLEIP 548
+D + +G A T TV G RL
Sbjct: 201 VDSDAADTASRPGTSTAALLAHLQRRREAMRAEGAPASPPSTGTRTCTVTEGKHARLSCY 260
Query: 549 ISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEA 608
++GEP P+ +W + + + EG + E ++ L I ++ D G+Y N G+
Sbjct: 261 VTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQT 320
Query: 609 HASIKVKV 616
++S+ V V
Sbjct: 321 YSSVLVVV 328
Score = 63.9 bits (154), Expect = 8e-10
Identities = 52/197 (26%), Positives = 83/197 (42%), Gaps = 12/197 (6%)
Query: 444 VNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 501
V++GK+ L C+I N + W K+ PV R ++ G +++L I + D G Y
Sbjct: 21 VSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQY 80
Query: 502 VF-APDAYNVTLPAKVHVIDPPKIILDG----LDADNTVTVIAGNKLRLEIPISGEPPPK 556
V A +A A +D + L ++ V G++ + G P P
Sbjct: 81 VCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPA 140
Query: 557 AMWSRGDKAIMEGSG-RIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVK 615
WS+ + + E G R+R E ++S L I A D G Y + +N G A A+ +
Sbjct: 141 VSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALV 200
Query: 616 VVDFPDPPVAPTVTEVG 632
V D A T + G
Sbjct: 201 V----DSDAADTASRPG 213
Score = 56.6 bits (135), Expect = 1e-07
Identities = 50/185 (27%), Positives = 82/185 (44%), Gaps = 12/185 (6%)
Query: 439 LTDQTVNLGKEICLKCEISENIPG--KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTE 496
L D T LG+ + L C ++ W K+G VQ ++ +I ++LT
Sbjct: 6020 LADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTG 6079
Query: 497 -DEGDYVF--APDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEP 553
D G Y+ A A N + K+ V PP+ + + + G + I G P
Sbjct: 6080 VDSGQYMCFAASAAGNCSTLGKILVQVPPRFV----NKVRASPFVEGEDAQFTCTIEGAP 6135
Query: 554 PPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDI--AERDDSGVYHINLKNEAGEAHAS 611
P+ W + D A++ + +T S P S LV+ I A ++D G+Y L N G A AS
Sbjct: 6136 YPQIRWYK-DGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARAS 6194
Query: 612 IKVKV 616
++++
Sbjct: 6195 AELRI 6199
Score = 56.2 bits (134), Expect = 2e-07
Identities = 46/178 (25%), Positives = 78/178 (43%), Gaps = 13/178 (7%)
Query: 536 TVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIR-TESYPDSSTLVIDIAERDDS 594
TV+ G + L +S +P +A WS+ D A +E S R+ + + + L I + +D
Sbjct: 7473 TVVLGQSVTLACQVSAQPAAQATWSK-DGAPLESSSRVLISATLKNFQLLTILVVVAEDL 7531
Query: 595 GVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGY 654
GVY ++ N G + ++ + P P + EV D ++ W+P + P+
Sbjct: 7532 GVYTCSVSNALGTVTTTGVLRKAERPSSSPCPDIGEVYADGVLLVWKP--VESYGPVT-- 7587
Query: 655 FIERKKKQSSRWMRLN---FDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPS 709
+I + + W L FD C T+ K+ G Y R V+ G+ S PS
Sbjct: 7588 YIVQCSLEGGSWTTLASDIFDCCYLTS----KLSRGGTYTFRTACVSKAGMGPYSSPS 7641
Score = 54.7 bits (130), Expect = 5e-07
Identities = 60/290 (20%), Positives = 103/290 (35%), Gaps = 29/290 (10%)
Query: 832 EIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI--DKNQINIRN 889
EI+EP LK +R +A + P E +W +GA + D + +
Sbjct: 4433 EILEP--------LKNAAVRAGAQACFTCTLSEAVPVGEASWYINGAAVQPDDSDWTVTA 4484
Query: 890 SETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVA 949
+ + +R A+ H+G+ + AS + ++ P PP+ ++ V
Sbjct: 4485 DGSHHALLLRSAQPHHAGEVTFACRD----AVASARLTVLGLPDPPEDAEVVARSSHTVT 4540
Query: 950 LTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSEN 1009
L+W P DG + GY ++ + + +W E + L G Y FRV +
Sbjct: 4541 LSWAAPMSDGGGGLCGYRVEVKEGATGQWRLCHELVPGPECVVDGLAPGETYRFRVAAVG 4600
Query: 1010 MCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCS 1069
G E + + + + P AP Q AG + +L
Sbjct: 4601 PVGAGEPVHLPQTVRLAEPPKPVPPQP--------SAPESRQ------VAAGEDVSLELE 4646
Query: 1070 VRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCC 1119
V ++ W K I R+ + S L I+ + D G Y C
Sbjct: 4647 VVAE-AGEVIWHKGMERIQPGGRFEVVSQGRQQMLVIKGFTAEDQGEYHC 4695
Score = 53.9 bits (128), Expect = 8e-07
Identities = 31/95 (32%), Positives = 51/95 (53%), Gaps = 2/95 (2%)
Query: 1043 FSEAPMF-TQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGV 1101
FS AP F T+P ++ G +ATL+C + GNP P+++W K++ + R+R+ + +
Sbjct: 6 FSGAPRFLTRPKAFVVSV-GKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDL 64
Query: 1102 CTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
L I + D G Y C+A N +G L+V
Sbjct: 65 YRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQV 99
Score = 53.1 bits (126), Expect = 1e-06
Identities = 32/94 (34%), Positives = 43/94 (45%), Gaps = 2/94 (2%)
Query: 1045 EAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKN--KVAIVDDPRYRMFSNQGVC 1102
+AP F + G AT C V G+P+P ++W K+ ++ D PR R+
Sbjct: 108 QAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEAS 167
Query: 1103 TLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
L IR P DGGTY +A N LG L V
Sbjct: 168 ALRIRAARPRDGGTYEVRAENPLGAASAAAALVV 201
Score = 52.4 bits (124), Expect = 2e-06
Identities = 81/369 (21%), Positives = 147/369 (39%), Gaps = 43/369 (11%)
Query: 356 GERVELECEVS-EDDANVKWFKNGEEIIPGPKSRYRIRVEGKKH-ILIIEGATKADAAEY 413
G+ L C V+ E W K+G+ + G R+ + + +++ +L I ++D Y
Sbjct: 252 GKHARLSCYVTGEPKPETVWKKDGQLVTEG--RRHVVYEDAQENFVLKILFCKQSDRGLY 309
Query: 414 SVMTTG--GQSSAKLSVDLKP--LKILTPLTDQTVNLGKEICLKCEISE-NIPGKWTKNG 468
+ + GQ+ + + V ++ + L D V + CE+ + + W K
Sbjct: 310 TCTASNLVGQTYSSVLVVVREPAVPFKKRLQDLEVREKESATFLCEVPQPSTEAAWFKEE 369
Query: 469 LPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF-APDAYNVTLPAKVHVIDPPKIILD 527
+ S + + +G +L + N +D+ Y+ P+ V +L
Sbjct: 370 TRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICETPEGSRTVAELAVQ-----GNLLR 424
Query: 528 GLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVID 587
L V V +E+ + P W R + ++ G GR+ + TL I
Sbjct: 425 KLPRKTAVRVGDTAMFCVELAV---PVGPVHWLRNQEEVVAG-GRVAISAEGTRHTLTIS 480
Query: 588 IAERDDSGVYHINLKNEAGEAHASIKVKVVDFP-----DPPVAPTVTEVGDDWCIMNWEP 642
+D G + AG+ S + V P PPV P V + I++W P
Sbjct: 481 QCCLEDVG----QVAFMAGDCQTSTQF-CVSAPRKPPLQPPVDPVVKARMESSVILSWSP 535
Query: 643 PAYDGGSPIL--GYFIERKKKQSSRWMRLNFDLCKETTF--EPKKMIEGVA----YEVRI 694
P + G P+ GY +E+KK + W+R C E + P+ + VA ++ R+
Sbjct: 536 PPH-GERPVTIDGYLVEKKKLGTYTWIR-----CHEAEWVATPELTVADVAEEGNFQFRV 589
Query: 695 FAVNAIGIS 703
A+N+ G S
Sbjct: 590 SALNSFGQS 598
Score = 51.6 bits (122), Expect = 4e-06
Identities = 30/92 (32%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Query: 1046 APMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSN-QGVCTL 1104
AP+F L N GY + +C V G P P + W K+ + +D Y + + QG L
Sbjct: 5125 APVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQL 5184
Query: 1105 EIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
I P D G Y C A N +G + +L V
Sbjct: 5185 IITAVVPADMGVYRCLAENSMGVSSTKAELRV 5216
Score = 50.1 bits (118), Expect = 1e-05
Identities = 30/93 (32%), Positives = 43/93 (46%), Gaps = 1/93 (1%)
Query: 1047 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSN-QGVCTLE 1105
P F + L + A G L C V G PKP I+W K+ A+ DP + + + G C L
Sbjct: 6014 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 6073
Query: 1106 IRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1138
+ + D G Y C A + G K+ V+V
Sbjct: 6074 LDSLTGVDSGQYMCFAASAAGNCSTLGKILVQV 6106
Score = 49.3 bits (116), Expect = 2e-05
Identities = 28/100 (28%), Positives = 44/100 (44%), Gaps = 2/100 (2%)
Query: 1040 DFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQ 1099
D + P + + A G A + G+P+P +TW K+ V +VD R
Sbjct: 6350 DTHTARPPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEG 6409
Query: 1100 GVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVI 1139
+L +R + D G Y C A N G ++ CK E+ V+
Sbjct: 6410 TTYSLVLRHVASKDAGVYTCLAQNTGG--QVLCKAELLVL 6447
Score = 48.9 bits (115), Expect = 3e-05
Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 2/93 (2%)
Query: 1047 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFS--NQGVCTL 1104
P F + + + G +A C++ G P P+I W K+ + +++ S G+ L
Sbjct: 6108 PRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVL 6167
Query: 1105 EIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1137
IR S D G Y C+ VN LG+ +L ++
Sbjct: 6168 VIRAASKEDLGLYECELVNRLGSARASAELRIQ 6200
Score = 48.1 bits (113), Expect = 5e-05
Identities = 72/323 (22%), Positives = 123/323 (38%), Gaps = 63/323 (19%)
Query: 213 LLKNAKPSEYEKIAFQYG--ITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRV 270
LLKN +P + ++ F G +T ++ + E K+AA V G +
Sbjct: 4400 LLKNLRPQDSCRVTFLAGDMVTSAFLTVRGWRLEILEPLKNAA----------VRAGAQA 4449
Query: 271 RFVVELAD--PKLEVKWYKNGQEIRPS-TKYIFEHKGCQRILFINNCQMTDDSEYYVTAG 327
F L++ P E WY NG ++P + + G L + + Q E
Sbjct: 4450 CFTCTLSEAVPVGEASWYINGAAVQPDDSDWTVTADGSHHALLLRSAQPHHAGEVTFACR 4509
Query: 328 DEKCSTELFVR---EPPI---MVTKQLEDTT------------AYCGERVELECEVSEDD 369
D S L V +PP +V + T CG RVE++ +
Sbjct: 4510 DAVASARLTVLGLPDPPEDAEVVARSSHTVTLSWAAPMSDGGGGLCGYRVEVK-----EG 4564
Query: 370 ANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGG--------- 420
A +W + E++PGP+ +++G + + V G
Sbjct: 4565 ATGQW-RLCHELVPGPEC-------------VVDGLAPGETYRFRVAAVGPVGAGEPVHL 4610
Query: 421 QSSAKLSVDLKPLKILTPLTD-QTVNLGKEICLKCEI-SENIPGKWTKNGLPVQESDRLK 478
+ +L+ KP+ + + V G+++ L+ E+ +E W K +Q R +
Sbjct: 4611 PQTVRLAEPPKPVPPQPSAPESRQVAAGEDVSLELEVVAEAGEVIWHKGMERIQPGGRFE 4670
Query: 479 VVHKGRIHKLVIANALTEDEGDY 501
VV +GR LVI ED+G+Y
Sbjct: 4671 VVSQGRQQMLVIKGFTAEDQGEY 4693
Score = 48.1 bits (113), Expect = 5e-05
Identities = 37/159 (23%), Positives = 68/159 (42%), Gaps = 7/159 (4%)
Query: 279 PKLEVKWYKNGQEIRPSTKYI-FEHKGCQRILFINNCQMTDDSEY--YVTAGDEKCST-- 333
PK + WYK+G+ ++ +I E L +++ D +Y + + CST
Sbjct: 6041 PKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMCFAASAAGNCSTLG 6100
Query: 334 ELFVREPPIMVTKQLEDTTAYCGERVELECEV-SEDDANVKWFKNGEEIIPGPKSRYRIR 392
++ V+ PP V K + + GE + C + ++W+K+G + G K +
Sbjct: 6101 KILVQVPPRFVNK-VRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSE 6159
Query: 393 VEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLK 431
+L+I A+K D Y SA+ S +L+
Sbjct: 6160 PRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELR 6198
Score = 46.2 bits (108), Expect = 2e-04
Identities = 33/114 (28%), Positives = 47/114 (41%), Gaps = 3/114 (2%)
Query: 1016 DATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPK 1075
D +M K + I K YK V ++ E PMF+ +T A G L C V
Sbjct: 4869 DPSMDKAAVKIQAAFKGYK--VRKEMKQQEGPMFSHTFGDTEAQVGDALRLECVVASKAD 4926
Query: 1076 PKITWMKNKVAIVDDPRYRMFS-NQGVCTLEIRKPSPYDGGTYCCKAVNDLGTV 1128
+ W+K+ V + D + + G C+L I D G Y C+ N G V
Sbjct: 4927 VRARWLKDGVELTDGRHHHIDQLGDGTCSLLITGLDRADAGCYTCQVSNKFGQV 4980
Score = 46.2 bits (108), Expect = 2e-04
Identities = 74/353 (20%), Positives = 126/353 (35%), Gaps = 81/353 (22%)
Query: 341 PIMVTKQLEDTTAYCGERVELECEVS-EDDANVKWFKNGEEIIPGPKSRYRIRVEGKK-H 398
P+ +T +L++ G V +C V+ + +V+WFK+G+ + Y I + + H
Sbjct: 5126 PVFLT-ELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLL--EEDDHYMINEDQQGGH 5182
Query: 399 ILIIEGATKADAAEYSVMTTGGQ----SSAKLSVDLKPLKILTPL--------------- 439
LII AD Y + + A+L VDL T
Sbjct: 5183 QLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYL 5242
Query: 440 -------TDQTVNLGK--EICLKCEISENIPGK------------------WTKNGLPVQ 472
T+ T + G+ ++ + + PG W K+G P+
Sbjct: 5243 SSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLT 5302
Query: 473 ESDRLKVVHKGRIHKLVIANALTEDEGDY------------------VFAPDAYNVTLPA 514
S +++ K +H L I + ED G Y V PD +
Sbjct: 5303 ASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPAS 5362
Query: 515 KVH-VIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSR--GDKAIM---- 567
VH + PP++ L+ V G+ + + + G P P W R ++ ++
Sbjct: 5363 DVHEQLVPPRM----LERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGP 5418
Query: 568 EGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFP 620
+ G S S +++D+ R G Y N AG+A S + V P
Sbjct: 5419 DTPGYTVASSAQQHSLVLLDVG-RQHQGTYTCIASNAAGQALCSASLHVSGLP 5470
Score = 42.7 bits (99), Expect = 0.002
Identities = 36/166 (21%), Positives = 65/166 (39%), Gaps = 12/166 (7%)
Query: 853 VGEAVNLVIPFQGKPRPELTWKKDGAEIDKN-----QINIRNSETDTIIFIRKAERSHSG 907
+G++V L +P + TW KDGA ++ + ++N + TI+ + + G
Sbjct: 7476 LGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLTILVVVAED---LG 7532
Query: 908 KYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYT 967
Y V T + ++ +RP I +V+ + V L W P + G Y
Sbjct: 7533 VYTCSVSNALGTVTTTGVLRKAERPSSSPCPDIGEVYADGVLLVWKPVESYGPVT---YI 7589
Query: 968 IQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL 1013
+Q + W T+ ++L G Y FR + G+
Sbjct: 7590 VQ-CSLEGGSWTTLASDIFDCCYLTSKLSRGGTYTFRTACVSKAGM 7634
Score = 41.2 bits (95), Expect = 0.006
Identities = 46/174 (26%), Positives = 70/174 (40%), Gaps = 26/174 (14%)
Query: 704 KPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTS 763
+ ++ S L + PP V + + TVT+ W P G GL GY +E EG+T
Sbjct: 4509 RDAVASARLTVLGLPDPPEDAEVVARSSHTVTLSWAAPMSDGGGGLCGYRVE-VKEGATG 4567
Query: 764 AKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKY 823
W + + +L+ + + GL RV AV GA EP +
Sbjct: 4568 -----------------QWRLCH-ELVPGPECVVDGLAPGETYRFRVAAVGPVGAGEPVH 4609
Query: 824 YSQPILVKEIIEPPKIRIPRHLKQTYIRRV--GEAVNLVIPFQGKPRPELTWKK 875
Q + + EPPK +P R+V GE V+L + + E+ W K
Sbjct: 4610 LPQTV---RLAEPPK-PVPPQPSAPESRQVAAGEDVSLELEVVAE-AGEVIWHK 4658
Score = 40.4 bits (93), Expect = 0.010
Identities = 30/110 (27%), Positives = 43/110 (39%), Gaps = 7/110 (6%)
Query: 1026 IARDGKIYKNPVYEDFDFS------EAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKIT 1079
+ ++G K P F S AP F + L + + G + TL C V P + T
Sbjct: 7436 LEKEGPPRKKPGLASFRLSGLKSWDRAPTFLRELSDETVVLGQSVTLACQVSAQPAAQAT 7495
Query: 1080 WMKNKVAIVDDPRYRMFSN-QGVCTLEIRKPSPYDGGTYCCKAVNDLGTV 1128
W K+ + R + + + L I D G Y C N LGTV
Sbjct: 7496 WSKDGAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYTCSVSNALGTV 7545
Score = 39.7 bits (91), Expect = 0.017
Identities = 35/138 (25%), Positives = 59/138 (42%), Gaps = 8/138 (5%)
Query: 537 VIAGNKL-RLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSG 595
V G +L + ++ + G P P+ W + D + S IR TL I R+DSG
Sbjct: 5271 VAPGTRLAKFQLKVKGYPAPRLYWFK-DGQPLTASAHIRMTDKKILHTLEIISVTREDSG 5329
Query: 596 VYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDW----CIMNWEPPAYDGGSPI 651
Y + N G A++S ++ +V PD P ++V + + + P GS I
Sbjct: 5330 QYAAYISNAMGAAYSSARL-LVRGPDEPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSI 5388
Query: 652 -LGYFIERKKKQSSRWMR 668
+E + + W+R
Sbjct: 5389 TFSVKVEGRPVPTVHWLR 5406
Score = 38.5 bits (88), Expect = 0.037
Identities = 22/67 (32%), Positives = 34/67 (50%), Gaps = 1/67 (1%)
Query: 1061 GYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSN-QGVCTLEIRKPSPYDGGTYCC 1119
G +A L+C V G PKP+ W K+ + + R+ ++ + Q L+I D G Y C
Sbjct: 252 GKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTC 311
Query: 1120 KAVNDLG 1126
A N +G
Sbjct: 312 TASNLVG 318
Score = 37.4 bits (85), Expect = 0.082
Identities = 22/69 (31%), Positives = 35/69 (50%), Gaps = 3/69 (4%)
Query: 436 LTPLTDQTVNLGKEICLKCEISEN--IPGKWTKNGLPVQESDRLKV-VHKGRIHKLVIAN 492
L L+D+TV LG+ + L C++S W+K+G P++ S R+ + L I
Sbjct: 7466 LRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLTILV 7525
Query: 493 ALTEDEGDY 501
+ ED G Y
Sbjct: 7526 VVAEDLGVY 7534
Score = 37.0 bits (84), Expect = 0.11
Identities = 27/86 (31%), Positives = 43/86 (50%), Gaps = 3/86 (3%)
Query: 330 KCSTELFVREPPIMVTKQLEDTTAYCGERVELECEV-SEDDANVKWFKNGEEIIPGPKSR 388
K E+ +E P M + DT A G+ + LEC V S+ D +W K+G E+ G +
Sbjct: 4887 KVRKEMKQQEGP-MFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDG-RHH 4944
Query: 389 YRIRVEGKKHILIIEGATKADAAEYS 414
+ ++ L+I G +ADA Y+
Sbjct: 4945 HIDQLGDGTCSLLITGLDRADAGCYT 4970
Score = 36.6 bits (83), Expect = 0.14
Identities = 38/166 (22%), Positives = 61/166 (36%), Gaps = 20/166 (12%)
Query: 992 ITELVIGNEYYFRVFSENMCGLSE-------DATMTK-ESAVIARDGKIY---------- 1033
IT +V + +R +EN G+S D T T ++A A + Y
Sbjct: 5186 ITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLSSR 5245
Query: 1034 -KNPVYEDFDFSEAPMFTQPLVNTYAIAGYN-ATLNCSVRGNPKPKITWMKNKVAIVDDP 1091
+ D + P + L + G A V+G P P++ W K+ +
Sbjct: 5246 EQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASA 5305
Query: 1092 RYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1137
RM + + TLEI + D G Y N +G +L V+
Sbjct: 5306 HIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVR 5351
Score = 35.8 bits (81), Expect = 0.24
Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 2/71 (2%)
Query: 1049 FTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRK 1108
F L N A G ATL C + + + W K + D RY + + +C L+IR
Sbjct: 3276 FIGKLRNKEATEGATATLRCEL--SKAAPVEWRKGSETLRDGDRYCLRQDGAMCELQIRG 3333
Query: 1109 PSPYDGGTYCC 1119
+ D Y C
Sbjct: 3334 LAMVDAAEYSC 3344
Score = 35.8 bits (81), Expect = 0.24
Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 2/71 (2%)
Query: 1049 FTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRK 1108
F + + N A G A L C + N + W K + D RY + + C L+IR
Sbjct: 3540 FIEDVKNQEAREGATAVLQCEL--NSAAPVEWRKGSETLRDGDRYSLRQDGTKCELQIRG 3597
Query: 1109 PSPYDGGTYCC 1119
+ D G Y C
Sbjct: 3598 LAMADTGEYSC 3608
Score = 35.4 bits (80), Expect = 0.31
Identities = 22/85 (25%), Positives = 38/85 (44%), Gaps = 13/85 (15%)
Query: 833 IIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDG---AEIDKNQINIRN 889
++ P IR+ + T+ RVG G PRP ++W KDG E D ++ +
Sbjct: 113 LLRPTSIRVREGSEATFRCRVG----------GSPRPAVSWSKDGRRLGEPDGPRVRVEE 162
Query: 890 SETDTIIFIRKAERSHSGKYDLQVK 914
+ + IR A G Y+++ +
Sbjct: 163 LGEASALRIRAARPRDGGTYEVRAE 187
Score = 35.4 bits (80), Expect = 0.31
Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 2/71 (2%)
Query: 1049 FTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRK 1108
FT+ L N A G A L C + + + W K + D R+ + + C L+IR
Sbjct: 3628 FTEGLRNEEATEGATAVLRCEL--SKMAPVEWWKGHETLRDGDRHSLRQDGARCELQIRG 3685
Query: 1109 PSPYDGGTYCC 1119
D G Y C
Sbjct: 3686 LVAEDAGEYLC 3696
Score = 34.7 bits (78), Expect = 0.53
Identities = 20/64 (31%), Positives = 32/64 (50%), Gaps = 1/64 (1%)
Query: 1058 AIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTY 1117
A AG +ATL+C V + ++TW K+ + + RM + L +++ D G Y
Sbjct: 1546 AEAGTSATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEY 1604
Query: 1118 CCKA 1121
CKA
Sbjct: 1605 SCKA 1608
Score = 34.3 bits (77), Expect = 0.69
Identities = 18/62 (29%), Positives = 30/62 (48%), Gaps = 2/62 (3%)
Query: 1058 AIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTY 1117
+I G ATL C + + + W K + ++ D R+ + + VC L+I + D G Y
Sbjct: 3373 SIEGATATLRCEL--SKAAPVEWRKGRESLRDGDRHSLRQDGAVCELQICGLAVADAGEY 3430
Query: 1118 CC 1119
C
Sbjct: 3431 SC 3432
Score = 34.3 bits (77), Expect = 0.69
Identities = 21/71 (29%), Positives = 31/71 (43%), Gaps = 2/71 (2%)
Query: 1049 FTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRK 1108
F + L N A G ATL C + + + W K + D R+ + + C L+IR
Sbjct: 3716 FIEGLRNEEATEGDTATLWCEL--SKAAPVEWRKGHETLRDGDRHSLRQDGSRCELQIRG 3773
Query: 1109 PSPYDGGTYCC 1119
+ D G Y C
Sbjct: 3774 LAVVDAGEYSC 3784
Score = 34.3 bits (77), Expect = 0.69
Identities = 17/59 (28%), Positives = 29/59 (49%), Gaps = 2/59 (3%)
Query: 853 VGEAVNLVIPFQGKPRPELTWKKDG--AEIDKNQINIRNSETDTIIFIRKAERSHSGKY 909
+GE V L G P+P ++W KDG ++D + I I + + + + SG+Y
Sbjct: 6027 LGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQY 6085
Score = 33.5 bits (75), Expect = 1.2
Identities = 20/83 (24%), Positives = 36/83 (43%), Gaps = 1/83 (1%)
Query: 1048 MFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIR 1107
+ T+PL + L+C R PK + W K+ + +++M + L I
Sbjct: 2470 VLTRPLEPKTGRELQSVVLSCDFRPAPKA-VQWYKDDTPLSPSEKFKMSLEGQMAELRIL 2528
Query: 1108 KPSPYDGGTYCCKAVNDLGTVEI 1130
+ P D G Y C+A + + E+
Sbjct: 2529 RLMPADAGVYRCQAGSAHSSTEV 2551
Score = 33.5 bits (75), Expect = 1.2
Identities = 20/80 (25%), Positives = 34/80 (42%), Gaps = 1/80 (1%)
Query: 1051 QPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPS 1110
+PL + + G + L C + P + W+K++ AI +Y + + L IR S
Sbjct: 2831 KPLEDQWVAPGEDVELRCELSRAGTP-VHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGAS 2889
Query: 1111 PYDGGTYCCKAVNDLGTVEI 1130
D G Y C+ T +
Sbjct: 2890 LKDAGEYTCEVEASKSTASL 2909
Score = 33.1 bits (74), Expect = 1.5
Identities = 19/64 (29%), Positives = 30/64 (46%), Gaps = 1/64 (1%)
Query: 1058 AIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTY 1117
A AG A L+C V P+ ++TW K+ + + RM L +++ D G Y
Sbjct: 1178 AEAGTTAMLSCEV-AQPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEY 1236
Query: 1118 CCKA 1121
C+A
Sbjct: 1237 SCEA 1240
Score = 33.1 bits (74), Expect = 1.5
Identities = 23/81 (28%), Positives = 35/81 (43%), Gaps = 7/81 (8%)
Query: 263 QVDKGGRVRF--VVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDS 320
Q GG +F ++E DP+ V WYK+ ++ ST+ + +G L + + D
Sbjct: 6367 QAQTGGTAQFEAIIE-GDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVASKDAG 6425
Query: 321 EYYV----TAGDEKCSTELFV 337
Y T G C EL V
Sbjct: 6426 VYTCLAQNTGGQVLCKAELLV 6446
Score = 32.7 bits (73), Expect = 2.0
Identities = 19/71 (26%), Positives = 30/71 (42%), Gaps = 5/71 (7%)
Query: 1066 LNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDL 1125
L C V +P+ + W K+ V + +Y G L + SP D G Y C +
Sbjct: 2666 LQCEV-SDPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYTC----HV 2720
Query: 1126 GTVEIECKLEV 1136
G+ E ++ V
Sbjct: 2721 GSEETRARVRV 2731
Score = 32.3 bits (72), Expect = 2.6
Identities = 20/92 (21%), Positives = 45/92 (48%), Gaps = 3/92 (3%)
Query: 854 GEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINI--RNSETDTIIFIRKAERSHSGKYDL 911
G+ L G+P+PE WKKDG + + + ++ +++ + ++ I ++S G Y
Sbjct: 252 GKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTC 311
Query: 912 QVKVDKFVETASIDIQIIDRPGPPQIVKIEDV 943
+ +T S + ++ P P +++D+
Sbjct: 312 TAS-NLVGQTYSSVLVVVREPAVPFKKRLQDL 342
Score = 32.3 bits (72), Expect = 2.6
Identities = 18/61 (29%), Positives = 29/61 (47%)
Query: 263 QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 322
QV G V +E+ EV W+K + I+P ++ +G Q++L I D EY
Sbjct: 4634 QVAAGEDVSLELEVVAEAGEVIWHKGMERIQPGGRFEVVSQGRQQMLVIKGFTAEDQGEY 4693
Query: 323 Y 323
+
Sbjct: 4694 H 4694
Score = 32.3 bits (72), Expect = 2.6
Identities = 25/107 (23%), Positives = 43/107 (40%), Gaps = 5/107 (4%)
Query: 517 HVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTE 576
H PP + + D V G + E I G+P P W + D + S R+ +
Sbjct: 6352 HTARPPSMQVTIED----VQAQTGGTAQFEAIIEGDPQPSVTWYK-DSVQLVDSTRLSQQ 6406
Query: 577 SYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPP 623
+ +LV+ D+GVY +N G+ ++ V+ + P
Sbjct: 6407 QEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLVLGGDNEP 6453
Score = 32.0 bits (71), Expect = 3.4
Identities = 22/82 (26%), Positives = 39/82 (47%), Gaps = 2/82 (2%)
Query: 1058 AIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTY 1117
A AG +ATL+C V + ++TW K+ + + M + L +++ D G Y
Sbjct: 902 AEAGASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEY 960
Query: 1118 CCKAVNDLGTVEIECKLEVKVI 1139
C+A + ++ K E KV+
Sbjct: 961 SCEAGGQRLSFHLDVK-EPKVV 981
Score = 32.0 bits (71), Expect = 3.4
Identities = 17/62 (27%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 1060 AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCC 1119
AG +ATL+C V + ++TW K+ + + R+ + + L +++ D G Y C
Sbjct: 1272 AGASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTC 1330
Query: 1120 KA 1121
+A
Sbjct: 1331 EA 1332
Score = 31.6 bits (70), Expect = 4.5
Identities = 18/64 (28%), Positives = 32/64 (50%), Gaps = 1/64 (1%)
Query: 1058 AIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTY 1117
A AG +ATL+C V + ++TW K+ + + R+ + L +++ D G Y
Sbjct: 1638 AEAGASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQADAGEY 1696
Query: 1118 CCKA 1121
C+A
Sbjct: 1697 SCEA 1700
Score = 31.6 bits (70), Expect = 4.5
Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 2/71 (2%)
Query: 1049 FTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRK 1108
FT+ L N A+ G A L C + + + W K + D RY + C L+I
Sbjct: 3452 FTEGLRNEEAVEGATAMLWCEL--SKVAPVEWRKGPENLRDGDRYILRQEGTRCELQICG 3509
Query: 1109 PSPYDGGTYCC 1119
+ D G Y C
Sbjct: 3510 LAMADAGEYLC 3520
Score = 30.8 bits (68), Expect = 7.7
Identities = 19/77 (24%), Positives = 36/77 (46%)
Query: 540 GNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHI 599
G+ LRLE ++ + +A W + + +G + + +L+I +R D+G Y
Sbjct: 4912 GDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLLITGLDRADAGCYTC 4971
Query: 600 NLKNEAGEAHASIKVKV 616
+ N+ G+ S V V
Sbjct: 4972 QVSNKFGQVTHSACVVV 4988
>gi|156104903 myomesin 2 [Homo sapiens]
Length = 1465
Score = 125 bits (314), Expect = 2e-28
Identities = 217/1002 (21%), Positives = 360/1002 (35%), Gaps = 199/1002 (19%)
Query: 230 GITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNG 289
G T R KR+ EE+++ + + L AY K R RF+ ELA + +V ++
Sbjct: 64 GGTICRVCAKRVSTQEDEEQENRSRYQSLVAAYGEAK--RQRFLSELAHLEEDVHLARS- 120
Query: 290 QEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLE 349
Q KY + QM +D A + E R P I+V +L
Sbjct: 121 QARDKLDKYAIQ-------------QMMEDK----LAWERHTFEERISRAPEILV--RLR 161
Query: 350 DTTAYCGERVELECEVSEDDANV-KWFKNGEEIIPGPK-SRYRIRVEGKKHILIIEGATK 407
T + V+L V V +W+K+G I + +YRI H L I A
Sbjct: 162 SHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADF 221
Query: 408 ADAAEYSVMTTG--GQSSAKLSVDLK------------------PLKILTPLTDQTVNL- 446
D A YS + T GQ S +V ++ PL + P T V
Sbjct: 222 DDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFL 281
Query: 447 ----------GKEICLKC------EISENIP-GKWTKNGLPVQESDRLKVVHKGRIHKLV 489
G+ + LKC ++ P +W ++ + ++ES K+ L
Sbjct: 282 EKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLS 341
Query: 490 IANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPI 549
++ +DEG Y + + ++ V D + DAD VT G + L+
Sbjct: 342 FSHLHKDDEG-------LYTLRIVSRGGVSDHSAFLFVR-DADPLVTGAPGAPMDLQCHD 393
Query: 550 SGEP-------PPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSG------- 595
+ PP + T ++ + + I + +G
Sbjct: 394 ANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSY 453
Query: 596 VYHINLKNEAG---------------------------EAHASIKVKVVDF------PDP 622
++ + N AG E I + D P P
Sbjct: 454 IFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGP 513
Query: 623 PVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLC-KETTFEP 681
P +E+ ++ +++WEPP G P++ YFIE+ S W R+N + +
Sbjct: 514 PTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAV 572
Query: 682 KKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVT---SPPTLLTVDSVTDTTVTMRW 738
++EG +Y R+ + N G+S+PS + P VT S P + T T+V ++W
Sbjct: 573 FDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQW 632
Query: 739 RPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTIT 798
P H L GY ++ C G+ W N I +F +
Sbjct: 633 DRPKH--EEDLLGYYVDCCVAGTNL------------------WEPCNHKPIGYNRFVVH 672
Query: 799 GLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRH-LKQTYIRRVGEAV 857
GL T + RVKAVNA G SE S I V+ + +P H T + G ++
Sbjct: 673 GLTTGEQYIFRVKAVNAVGMSENSQESDVIKVQ-----AALTVPSHPYGITLLNCDGHSM 727
Query: 858 NL--VIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKV 915
L +P P L + D E+ + NS + + Y+ ++
Sbjct: 728 TLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAA 787
Query: 916 DKFV---------ETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGY 966
E + + PGP + +V ++ + W P G++ ++GY
Sbjct: 788 VNLAGIGEPSDPSEHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGY 847
Query: 967 TIQKADKKSMEWFTVIEHYHRTSAT----ITELVIGNEYYFRVFSENMCGLSEDATMTKE 1022
+ ++ + EW TV + T+A +++L G Y FRV + N G+ + + ++
Sbjct: 848 FVDFREEDAGEWITVNQ---TTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEP 904
Query: 1023 SAVIARDGK-------IYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPK 1075
V AR G + +Y FD E +Q
Sbjct: 905 VLVEARPGTKEISAGVDEQGNIYLGFDCQEMTDASQ------------------------ 940
Query: 1076 PKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTY 1117
TW K+ I DD R+++ + L ++ P D GTY
Sbjct: 941 --FTWCKSYEEISDDERFKIETVGDHSKLYLKNPDKEDLGTY 980
Score = 110 bits (274), Expect = 1e-23
Identities = 130/565 (23%), Positives = 220/565 (38%), Gaps = 72/565 (12%)
Query: 596 VYHINLKNEAGEAHAS-----IKVKV-VDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGS 649
++ + N G + S IKV+ + P P T+ + W+ P + GGS
Sbjct: 681 IFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGS 740
Query: 650 PILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPS 709
PILGY++++++ W +N K T + EG YE +I AVN GI +PS PS
Sbjct: 741 PILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPS 800
Query: 710 RPFVPLAVTSP---PTL-LTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAK 765
F A T P P LT V DT++ M W+ P + G++ + GY +++ +
Sbjct: 801 EHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDF--------R 852
Query: 766 QSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYS 825
+ D A +WI N+ ++ L RV+AVNA G +P S
Sbjct: 853 EED----------AGEWITVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTS 902
Query: 826 QPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPF---QGKPRPELTWKKDGAEI-D 881
+P+LV+ R + V E N+ + F + + TW K EI D
Sbjct: 903 EPVLVE----------ARPGTKEISAGVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISD 952
Query: 882 KNQINIRNSETDTIIFIRKAERSHSGKYDLQVK-VDKFVETASIDIQIIDR--------P 932
+ I + ++++ ++ G Y + V D + +D + ++R
Sbjct: 953 DERFKIETVGDHSKLYLKNPDKEDLGTYSVSVSDTDGVSSSFVLDPEELERLMALSNEIK 1012
Query: 933 GPPQIVKIE---DVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTS 989
P +K E +++ + W + A + I + E I
Sbjct: 1013 NPTIPLKSELAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSDSE----IHRIKCDK 1068
Query: 990 AT-ITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPM 1048
AT I E+V+ F + +E + K + + G +K V E+ +F
Sbjct: 1069 ATGIIEMVMDR---FSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKT-VLEEAEFQRKEF 1124
Query: 1049 FTQPLVNTYAIAGYNATLNCSVR-----GNPKPK--ITWMKNKVAIVDDPRYRMFSNQGV 1101
+ + ++ T C VR N K + W+K+ V + + +G+
Sbjct: 1125 LRKQGPHFAEYLHWDVTEECEVRLVCKVANTKKETVFKWLKDDVLYETETLPNL--ERGI 1182
Query: 1102 CTLEIRKPSPYDGGTYCCKAVNDLG 1126
C L I K S D G Y +D G
Sbjct: 1183 CELLIPKLSKKDHGEYKATLKDDRG 1207
Score = 45.4 bits (106), Expect = 3e-04
Identities = 92/464 (19%), Positives = 162/464 (34%), Gaps = 92/464 (19%)
Query: 238 LKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVV--ELADPKLEVKWYKNGQEIRPS 295
L+RL + E K K + AY++ GRVRF + E P ++ N +E+ S
Sbjct: 1001 LERLMALSNEIKNPTIPLKS-ELAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSDS 1059
Query: 296 TKYIFEHKGCQRIL--FINNCQMTDDSEYYVTAGDEKCSTEL------------------ 335
+ + I+ ++ + ++ Y V D K ++
Sbjct: 1060 EIHRIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEF 1119
Query: 336 ----FVREPPIMVTKQLE-DTTAYCGERVELECEVSEDDANVKWFKNG----EEIIPGPK 386
F+R+ + L D T C R+ + ++ + KW K+ E +P
Sbjct: 1120 QRKEFLRKQGPHFAEYLHWDVTEECEVRLVCKVANTKKETVFKWLKDDVLYETETLPN-- 1177
Query: 387 SRYRIRVEGKKHILIIEGATKADAAEY------------SVMTTGGQ--------SSAKL 426
+E L+I +K D EY S++ G+ S
Sbjct: 1178 ------LERGICELLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGKVYDDMILAMSRVC 1231
Query: 427 SVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVVHKGRIH 486
PLK+L T + + L C ++ + W + S+ +++ +
Sbjct: 1232 GKSASPLKVLC--TPEGIRLQ---CFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMA 1286
Query: 487 KLVIANALTEDEGDYVF----APDAYNVTLPAKVHVIDPPKIILDGLDA----------- 531
L I +D+G Y F D + +L D A
Sbjct: 1287 WLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGRL 1346
Query: 532 ----DNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIM---EGSGRIRTESYPDSSTL 584
+ VT++ G L L + G P P+ +W + D+ I S ++ Y ++
Sbjct: 1347 IGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKY---VSM 1403
Query: 585 VIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPD--PPVAP 626
I +DSG Y IN+KN+ G + V V + P +AP
Sbjct: 1404 TIKGVTSEDSGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAP 1447
Score = 40.0 bits (92), Expect = 0.013
Identities = 25/72 (34%), Positives = 35/72 (48%), Gaps = 3/72 (4%)
Query: 1069 SVRGNPKPKITWMKNKVAI---VDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDL 1125
+V+G P P + W K+ I + +YR+ SN GV TLEI + D TY A N
Sbjct: 176 TVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAH 235
Query: 1126 GTVEIECKLEVK 1137
G V + V+
Sbjct: 236 GQVSTNAAVVVR 247
Score = 35.4 bits (80), Expect = 0.31
Identities = 21/77 (27%), Positives = 33/77 (42%), Gaps = 1/77 (1%)
Query: 1061 GYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQG-VCTLEIRKPSPYDGGTYCC 1119
G L C+V GNP P++ W KN I + + Q ++ I+ + D G Y
Sbjct: 1359 GKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSI 1418
Query: 1120 KAVNDLGTVEIECKLEV 1136
N G +I+ + V
Sbjct: 1419 NIKNKYGGEKIDVTVSV 1435
Score = 31.2 bits (69), Expect = 5.9
Identities = 22/94 (23%), Positives = 41/94 (43%), Gaps = 8/94 (8%)
Query: 854 GEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ-INIRNSETDTI-IFIRKAERSHSGKYDL 911
G+ +NL G P PE+ W K+ +I ++ +++ + + + I+ SGKY +
Sbjct: 1359 GKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSI 1418
Query: 912 QVKVDKFVETASIDIQI------IDRPGPPQIVK 939
+K E + + + I PPQ K
Sbjct: 1419 NIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAK 1452
>gi|140560917 myomesin 1 isoform b [Homo sapiens]
Length = 1589
Score = 122 bits (307), Expect = 1e-27
Identities = 207/927 (22%), Positives = 327/927 (35%), Gaps = 188/927 (20%)
Query: 279 PKLEVKWYKNGQEIRPST---KYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTEL 335
P+ V WYKN I KYI E + L IN C D ++Y +A + K
Sbjct: 304 PEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRASAMNVKGELSA 363
Query: 336 FVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEG 395
+ +V K+ Y GE E F G +P
Sbjct: 364 YAS----VVVKR------YKGEFDETR------------FHAGASTMP------------ 389
Query: 396 KKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCE 455
+ V G S ++ D K + +T++LG + + E
Sbjct: 390 ---------------LSFGVTPYGYASRFEIHFDDK-FDVSFGREGETMSLGCRVVITPE 433
Query: 456 ISENIPG-KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDE---------GDYVFAP 505
I P +W +NG+P+ S ++ + G L ++ EDE G+Y
Sbjct: 434 IKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQY 493
Query: 506 DAYNVTLPAKVHVIDPPKIILD--GLDADNTVTVIAGNKLRLE--IPISGEPPPKA---- 557
AY A + P LD L+A+ +I+ + ++ PI G K
Sbjct: 494 SAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGT 553
Query: 558 -MWSRGD-----------KAIMEGSG---RIRT--------ESYPDSSTLVIDIAERDDS 594
WS+ + ++EG R+R S +D AE+
Sbjct: 554 DSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEK--- 610
Query: 595 GVYHINLKNEAGEAHASIKVKVVDFPD------PPVAPTVTEVGDDWCIMNWEPPAYDGG 648
LK+ + + P PP +VTE + +++W+PP G
Sbjct: 611 ----ARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGH 666
Query: 649 SPILGYFIERKKKQSSRWMRLNFDL-CKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSM 707
I+ YF+E+ + + W R+N +L K F + EG +Y R+ N+ G+ +PS
Sbjct: 667 EGIM-YFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSE 725
Query: 708 PSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSA 764
+ V L + P + TDT+V + W + A L GY +E GS
Sbjct: 726 ATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWE--ESKDAKELVGYYIEASVAGSGK- 782
Query: 765 KQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYY 824
W N + + ++FT GL T RV+AVNAAG SE
Sbjct: 783 -----------------WEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQD 825
Query: 825 SQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ 884
S+ I VK I PP T + +++ L G +P+ K GAEI
Sbjct: 826 SEAIEVKAAIAPPS----PPCDITCLESFRDSMVL-----GWKQPD---KIGGAEITGYY 873
Query: 885 INIRN---------SETDTIIFIRKAERSHSGK----YDLQVKVDKFV---------ETA 922
+N R E + +A + + K Y QV E
Sbjct: 874 VNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECF 933
Query: 923 SIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGY--TIQKADKKSMEWFT 980
+ I PGPP +K +V +++ L W PP G +TGY +++A K +W
Sbjct: 934 KCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRG 993
Query: 981 VIE-HYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYE 1039
+ E + L G Y FRV + N G+ + + + R G
Sbjct: 994 LNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGT-------- 1045
Query: 1040 DFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQ 1099
+ +VN + C + PK + +W K+ V+ D PR + S
Sbjct: 1046 ----------KEVVVNVDDDGVISLNFECD-KMTPKSEFSWSKDYVSTEDSPRLEVESKG 1094
Query: 1100 GVCTLEIRKPSPYDGGTYCCKAVNDLG 1126
+ + D G Y C + G
Sbjct: 1095 NKTKMTFKDLGMDDLGIYSCDVTDTDG 1121
Score = 91.3 bits (225), Expect = 5e-18
Identities = 128/584 (21%), Positives = 219/584 (37%), Gaps = 85/584 (14%)
Query: 594 SGVYHINLKNEAGEAHAS-----IKVKV-VDFPDPPVAPTVTEVGDDWCIMNWEPPAYDG 647
S ++ + N AG + S I+VK + P PP T E D ++ W+ P G
Sbjct: 806 SYIFRVRAVNAAGLSEYSQDSEAIEVKAAIAPPSPPCDITCLESFRDSMVLGWKQPDKIG 865
Query: 648 GSPILGYFIERKKKQSS---RWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISK 704
G+ I GY++ ++ +W N E ++ + E + Y+ ++ A+N G+
Sbjct: 866 GAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGA 925
Query: 705 PSMPSRPFV----PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEG 760
PS S F +AV PP L V ++ ++W+PP H G + GY ++
Sbjct: 926 PSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDL---K 982
Query: 761 STSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASE 820
AK+ + W N+ I + GL RV+A+N AG +
Sbjct: 983 EAKAKE-------------DQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGK 1029
Query: 821 PKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQ---GKPRPELTWKKDG 877
P + P++ + R + + V + + + F+ P+ E +W KD
Sbjct: 1030 PSDLAGPVVAE----------TRPGTKEVVVNVDDDGVISLNFECDKMTPKSEFSWSKDY 1079
Query: 878 AEI-DKNQINIRNSETDTIIFIRKAERSHSGKYDLQV-KVDKFVETASIDIQIIDR---- 931
D ++ + + T + + G Y V D + ID + + R
Sbjct: 1080 VSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLAL 1139
Query: 932 ------PGPP--QIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIE 983
P P + +E + V K GNA + Y +K+ E
Sbjct: 1140 SHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKV-NYIFN--EKEIFEGPKYKM 1196
Query: 984 HYHRTSATITELVIGNEYYFRVFSENMCGL----SEDATMTKESAVIARDGKIYKNPVYE 1039
H R + I E + + G +D T S V+ G ++K + +
Sbjct: 1197 HIDRNTGII-------EMFMEKLQDEDEGTYTFQLQDGKATNHSTVVL-VGDVFKK-LQK 1247
Query: 1040 DFDF-------SEAPMFTQPLVNTYAIAG-YNATLNCSVRGNPK-PKITWMKNKVAIVDD 1090
+ +F + P F + L ++ + G N L C V K I W K++ I D
Sbjct: 1248 EAEFQRQEWIRKQGPHFVEYL--SWEVTGECNVLLKCKVANIKKETHIVWYKDEREISVD 1305
Query: 1091 PRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKL 1134
++ G+CTL I + S D G Y +D G + KL
Sbjct: 1306 EKHDF--KDGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKL 1347
Score = 57.4 bits (137), Expect = 8e-08
Identities = 101/453 (22%), Positives = 166/453 (36%), Gaps = 92/453 (20%)
Query: 238 LKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVV--ELADPKLEVKWYKNGQEIRPS 295
LKRL + E K K + A ++ + G+VRF + E +V + N +EI
Sbjct: 1133 LKRLLALSHEHKFPTVPVKS-ELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFEG 1191
Query: 296 TKY---IFEHKGCQRILFINNCQMTDDSEYYVTAGDEKC---STELFVREPPIMVTKQLE 349
KY I + G +F+ Q D+ Y D K ST + V + + K+ E
Sbjct: 1192 PKYKMHIDRNTGIIE-MFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQKEAE 1250
Query: 350 --------------------DTTAYCGERVELECEVS--EDDANVKWFKNGEEIIPGPKS 387
+ T C V L+C+V+ + + ++ W+K+ EI K
Sbjct: 1251 FQRQEWIRKQGPHFVEYLSWEVTGECN--VLLKCKVANIKKETHIVWYKDEREISVDEKH 1308
Query: 388 RYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLG 447
++ +G +LI E +K DA Y V+ + K + L + + L
Sbjct: 1309 DFK---DGICTLLITE-FSKKDAGIYEVILKDDRGKDKSRLKL--------VDEAFKELM 1356
Query: 448 KEICLKCEIS-----------------------ENIPGKWTKNGLPVQESDRLKVVHKGR 484
E+C K +S E++ W+ NG ++ SDR+K G
Sbjct: 1357 MEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGE 1416
Query: 485 IHKLVIANALTEDEGDYVF----APDAYNVTLPAKVHVIDPPKI---------------- 524
L I D+G YV + T+ D
Sbjct: 1417 QIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRA 1476
Query: 525 -ILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSST 583
+L GL + VT+ G L L + G+PPP+ W + +KA+ ++
Sbjct: 1477 RVLGGL--PDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAY 1534
Query: 584 LVIDIAERDDSGVYHINLKNEAGEAHASIKVKV 616
I+ DSG Y + +KN+ G + V V
Sbjct: 1535 FTINGVSTADSGKYGLVVKNKYGSETSDFTVSV 1567
Score = 45.8 bits (107), Expect = 2e-04
Identities = 27/78 (34%), Positives = 40/78 (51%), Gaps = 3/78 (3%)
Query: 1063 NATLNCSVRGNPKPKITWMKNKVAI---VDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCC 1119
N L+CS+ G P+P++TW KN+V I + +Y + S G+ TLEI D Y
Sbjct: 293 NVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRA 352
Query: 1120 KAVNDLGTVEIECKLEVK 1137
A+N G + + VK
Sbjct: 353 SAMNVKGELSAYASVVVK 370
Score = 40.8 bits (94), Expect = 0.007
Identities = 35/139 (25%), Positives = 62/139 (44%), Gaps = 4/139 (2%)
Query: 811 KAVNAAGASEPKYYSQPILVKE--IIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPR 868
K V+ +G + + Y++ +K+ I E + R+ L + G+A+NL G P
Sbjct: 1446 KTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPP 1505
Query: 869 PELTW-KKDGAEIDKNQINIRNSETDTIIF-IRKAERSHSGKYDLQVKVDKFVETASIDI 926
PE++W K + A + N++ T F I + SGKY L VK ET+ +
Sbjct: 1506 PEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTV 1565
Query: 927 QIIDRPGPPQIVKIEDVWG 945
+ ++ +E + G
Sbjct: 1566 SVFIPEEEARMAALESLKG 1584
Score = 36.2 bits (82), Expect = 0.18
Identities = 38/147 (25%), Positives = 61/147 (41%), Gaps = 17/147 (11%)
Query: 473 ESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDAD 532
E KVV + + +L + L E E Y+ L H++ P+ I+
Sbjct: 237 EKKSRKVVIREKAERLSLRKTLEETE--------TYHAKLNED-HLLHAPEFIIK----P 283
Query: 533 NTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAI--MEGSGRIRTESYPDSSTLVIDIAE 590
+ TV ++L I+G P P+ W + I G+ ES TL I+ +
Sbjct: 284 RSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCD 343
Query: 591 RDDSGVYHINLKNEAGE--AHASIKVK 615
+D+ Y + N GE A+AS+ VK
Sbjct: 344 FEDTAQYRASAMNVKGELSAYASVVVK 370
Score = 36.2 bits (82), Expect = 0.18
Identities = 20/68 (29%), Positives = 30/68 (44%), Gaps = 1/68 (1%)
Query: 1061 GYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRM-FSNQGVCTLEIRKPSPYDGGTYCC 1119
G L C+V G+P P+++W+KN+ A+ D + F I S D G Y
Sbjct: 1491 GKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGL 1550
Query: 1120 KAVNDLGT 1127
N G+
Sbjct: 1551 VVKNKYGS 1558
Score = 30.8 bits (68), Expect = 7.7
Identities = 41/180 (22%), Positives = 68/180 (37%), Gaps = 21/180 (11%)
Query: 270 VRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYY--VTAG 327
+ F + PK E W K+ S + E KG + + + M D Y VT
Sbjct: 1060 LNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDT 1119
Query: 328 DEKCSTELFVRE--------------PPIMVTKQLEDTTAYCGE-RVELECEVSEDDANV 372
D S+ L E P + V +L G+ R ++ E +A V
Sbjct: 1120 DGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKV 1179
Query: 373 KWFKNGEEIIPGPKSRYRIRVEGKKHI--LIIEGATKADAAEYSVMTTGGQSSAKLSVDL 430
+ N +EI GPK Y++ ++ I + +E D Y+ G+++ +V L
Sbjct: 1180 NYIFNEKEIFEGPK--YKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVL 1237
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 119 bits (297), Expect = 2e-26
Identities = 199/893 (22%), Positives = 344/893 (38%), Gaps = 118/893 (13%)
Query: 279 PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVT----AGDEKCSTE 334
P ++ W+K+G+ + + E ++L + N + D Y T AG + +
Sbjct: 1481 PFPDIHWFKDGKPLFLGDPNV-ELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIK 1539
Query: 335 LFVREPP-IMVTKQLEDTTAYCGERVELECEVSE-DDANVKWFKNGEEIIPGPKSRYRIR 392
L + PP I D + ++LECE + W+K+G+ I+ ++ Y
Sbjct: 1540 LTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYI-- 1597
Query: 393 VEGKKHILIIEGATKADAAEYS--VMTTGGQSSAKLSVDL--KPL---KILTPLTDQTVN 445
K L I A +D+A Y+ V G + VD+ P+ + TPL Q V
Sbjct: 1598 --DKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVV- 1654
Query: 446 LGKEICLKCEISENIPG--KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF 503
+ + L+C+ + N W K+G+PV+ +D +++ G+ KL I +A D G Y+
Sbjct: 1655 IAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGK--KLEIMSAQEIDRGQYIC 1712
Query: 504 APD--AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSR 561
A + +V V+ PP I +G D + V+ N L L+ ++G PPP MW +
Sbjct: 1713 VATSVAGEKEIKYEVDVLVPPAI--EGGDETSYFIVMVNNLLELDCHVTGSPPPTIMWLK 1770
Query: 562 GDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPD 621
+ I E G + + LVI A+ ++G+Y N AG+ +V V
Sbjct: 1771 DGQLIDERDG---FKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTV----- 1822
Query: 622 PPVAPTVTEVG-DDWCIMNWEPPAYD---GGSPILGY-FIERKKKQSSRWMRLNFDLCKE 676
V PT+ G + ++ ++P A G P +++ + ++ L
Sbjct: 1823 -HVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGR 1881
Query: 677 TTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTM 736
K ++E A A NA G ++ + L V PP+L + + TV +
Sbjct: 1882 VLQIAKTLLED-AGRYTCVATNAAG------ETQQHIQLHVHEPPSLEDAGKMLNETVLV 1934
Query: 737 RWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFT 796
S E A +P W N+ L T T
Sbjct: 1935 --------------------------SNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMT 1968
Query: 797 I----------TGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLK 846
+ +DA I+ + A+N+AGA+E +YS + V P I ++
Sbjct: 1969 FLNRGQIIDIESAQISDAGIY-KCVAINSAGATE-LFYSLQVHV-----APSISGSNNMV 2021
Query: 847 QTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHS 906
V V L +G P P LTW KDG+ + ++ I+ + A+ S +
Sbjct: 2022 AVV---VNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDT 2078
Query: 907 GKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGY 966
G+Y + ID+++ PP I+ E +NV++ + +
Sbjct: 2079 GRYTCVAVNAAGEKQRDIDLRVY---VPPNIMGEE----QNVSVLISQAVE--------- 2122
Query: 967 TIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVI 1026
+ ++D T ++ H + N ++ + + T E+ +
Sbjct: 2123 LLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQ---VQDTGRYTCEATNV 2179
Query: 1027 A-RDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKV 1085
A + K Y ++ + + TQ V I G +L C G P P + W K
Sbjct: 2180 AGKTEKNYNVNIWVPPNIGGSDELTQLTV----IEGNLISLLCESSGIPPPNLIWKKKGS 2235
Query: 1086 AIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1138
++ D R+ G L+I D Y C A N GT + E L+V +
Sbjct: 2236 PVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYI 2288
Score = 114 bits (285), Expect = 5e-25
Identities = 182/860 (21%), Positives = 312/860 (36%), Gaps = 143/860 (16%)
Query: 326 AGDEKCSTELFVREPPIMVTKQLEDTTAY----CGERVELECEVS-EDDANVKWFKNGEE 380
AG ++ L V+EPP + + T + +R+E C +KW NG E
Sbjct: 1247 AGTDETEITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGRE 1306
Query: 381 IIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKP-----LKI 435
+ G + I +G +L+I T D EY + + + +LK +K
Sbjct: 1307 LT-GREPGISILEDGT--LLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKD 1363
Query: 436 LTPLTDQTVNLGKEICLKCEISENIPGK---WTKNGLPVQESDRLKVVHKGRIHKLVIAN 492
+T+ +V L + L CE+ E P W K+ + V ES ++ V+ G+I KL
Sbjct: 1364 KEQVTNVSVLLNQLTNLFCEV-EGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLF--R 1420
Query: 493 ALTEDEGDYVFAPDAYNVTLPAK----VHVIDPPKIILDGLDADNTVTVIAGNKLRLEIP 548
A ED G Y + A N+ ++ + V+ PP II G + N V+V+ + LE
Sbjct: 1421 ATPEDAGRY--SCKAINIAGTSQKYFNIDVLVPPTII--GTNFPNEVSVVLNRDVALECQ 1476
Query: 549 ISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEA 608
+ G P P W + K + G + E L + A R+D G Y + N AG+
Sbjct: 1477 VKGTPFPDIHWFKDGKPLFLGDPNV--ELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQ 1534
Query: 609 HASIKVKVVDFPDPPVAPTVTEV---------------GDDWCIMNWEPPAYDGGSPILG 653
IK+ + P T++ G + W Y G PI+
Sbjct: 1535 AKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITW----YKDGQPIM- 1589
Query: 654 YFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV 713
S L D + ++ + Y + N G ++ S +V
Sbjct: 1590 ----------SSSQALYIDKGQYLHIPRAQVSDSATYTCHV--ANVAGTAEKSFHVDVYV 1637
Query: 714 PLAVT-SPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGE 772
P + + T L V ++T+ + AAG +L + +G + E
Sbjct: 1638 PPMIEGNLATPLNKQVVIAHSLTLECK------AAGNPSPILTWLKDGVPVKANDNIRIE 1691
Query: 773 AAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKE 832
A + + + ID+ ++ A + AG E KY +
Sbjct: 1692 AG----GKKLEIMSAQEIDRGQYICV-------------ATSVAGEKEIKY------EVD 1728
Query: 833 IIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDK---------- 882
++ PP I +I V + L G P P + W KDG ID+
Sbjct: 1729 VLVPPAIEGGDETSY-FIVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNG 1787
Query: 883 NQINIRNSETDTIIFIR----KAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIV 938
++ I ++ R H ++++ V V ++++ + +++ + P +
Sbjct: 1788 RKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQ 1847
Query: 939 KIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIG 998
I + N ++TW N A IQ + + T++E R + T
Sbjct: 1848 CIAN-GIPNPSITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGE 1906
Query: 999 NEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYA 1058
+ + ++ L + M E+ +++ NPV
Sbjct: 1907 TQQHIQLHVHEPPSLEDAGKMLNETVLVS-------NPV--------------------- 1938
Query: 1059 IAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYC 1118
L C GNP P ITW K+ ++ F N+G ++I D G Y
Sbjct: 1939 ------QLECKAAGNPVPVITWYKDN-RLLSGSTSMTFLNRGQ-IIDIESAQISDAGIYK 1990
Query: 1119 CKAVNDLGTVEIECKLEVKV 1138
C A+N G E+ L+V V
Sbjct: 1991 CVAINSAGATELFYSLQVHV 2010
Score = 112 bits (281), Expect = 2e-24
Identities = 194/897 (21%), Positives = 330/897 (36%), Gaps = 115/897 (12%)
Query: 278 DPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFV 337
+P + WYK+ + + ST F ++G +I+ I + Q++D Y A + +TELF
Sbjct: 1947 NPVPVITWYKDNRLLSGSTSMTFLNRG--QIIDIESAQISDAGIYKCVAINSAGATELFY 2004
Query: 338 R-----EPPIMVTKQLEDTTAYCGERVELECEVSEDDA-NVKWFKNGEEIIPGPKSRYRI 391
P I + + V LECE A ++ W K+G P +
Sbjct: 2005 SLQVHVAPSISGSNNM--VAVVVNNPVRLECEARGIPAPSLTWLKDGS---PVSSFSNGL 2059
Query: 392 RVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLK---PLKILTPLTDQTVNLGK 448
+V IL + A +D Y+ + + +DL+ P I+ + +V + +
Sbjct: 2060 QVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQ 2119
Query: 449 EICLKCEISENIPGK---WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAP 505
+ L C+ S+ IP W K+G P+ + L + + K I +A +D G Y
Sbjct: 2120 AVELLCQ-SDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLK--IEDAQVQDTGRYTC-- 2174
Query: 506 DAYNVTLPAK----VHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMW-S 560
+A NV + V++ PP I G D +TVI GN + L SG PPP +W
Sbjct: 2175 EATNVAGKTEKNYNVNIWVPPNI--GGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKK 2232
Query: 561 RGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFP 620
+G + + GR+R S L I IAE+ D+ +Y N AG A ++V
Sbjct: 2233 KGSPVLTDSMGRVRILS--GGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVY--- 2287
Query: 621 DPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFE 680
+ PT+T G E G S L ++ + WM+ L K E
Sbjct: 2288 ---IRPTITNSGSH----PTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVE 2340
Query: 681 PKKMIEGVAYEVRIFAVN------AIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTV 734
+ EG +++ V+ + ++ M + + L+V +PP+++
Sbjct: 2341 --ILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKY-DLSVHAPPSIIG--------- 2388
Query: 735 TMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTK 794
R P++I + L G + L I++ ++ +
Sbjct: 2389 --NHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQ 2446
Query: 795 FTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVG 854
T+ DA + V V A E K + +LV PP I L+ ++
Sbjct: 2447 TTM----EDAGQYTCV--VRNAAGEERKIFGLSVLV-----PPHIVGENTLEDVKVKE-K 2494
Query: 855 EAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVK 914
++V L G P PE+TW KDG + +++ + + I + H+G+Y
Sbjct: 2495 QSVTLTCEVTGNPVPEITWHKDGQPLQEDEAH-HIISGGRFLQITNVQVPHTGRYTCLAS 2553
Query: 915 VDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKK 974
++ S + + P T DGN +
Sbjct: 2554 SPAGHKSRSFSLNVFVSP------------------TIAGVGSDGNPEDVTVILNSPTS- 2594
Query: 975 SMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYK 1034
V E Y ATIT G + G + + R +
Sbjct: 2595 -----LVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVAT 2649
Query: 1035 NPVYEDFDFSEAPMFTQPLVNTYAIAG-------------YNATLNCSVRGNPKPKITWM 1081
N E E ++ P++N + G TL C P ++W
Sbjct: 2650 NEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWY 2709
Query: 1082 KNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1138
K+ + D + +N TL+I++ D G Y C A N G E++ + ++V
Sbjct: 2710 KDGQPLKSDDHVNIAANGH--TLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQV 2764
Score = 107 bits (267), Expect = 6e-23
Identities = 210/909 (23%), Positives = 331/909 (36%), Gaps = 142/909 (15%)
Query: 278 DPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTA----GDEKCST 333
+P E +W KN + + G L I Q+ D EY A G +T
Sbjct: 917 NPIPERRWIKNSAMLLQNPYITVRSDGS---LHIERVQLQDGGEYTCVASNVAGTNNKTT 973
Query: 334 ELFVRE-PPIMVTKQLEDTTAYCGERVELECEVSEDDA-NVKWFKNGEEIIPGPKSRYRI 391
+ V P I +Q+ T G V L C+ S + +V W K GE +I +++
Sbjct: 974 SVVVHVLPTIQHGQQILSTIE--GIPVTLPCKASGNPKPSVIWSKKGE-LISTSSAKFSA 1030
Query: 392 RVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQ--------- 442
+G +++ G ++ EY T AK V L DQ
Sbjct: 1031 GADGSLYVVSPGGE---ESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPV 1087
Query: 443 --TVNLGKEICLKCEISENIPG--KWTKNGLPVQE-SDRLKVVHKGRIHKLVIANALTED 497
+V G+E+ L CE+ P W K + S R + G + I T D
Sbjct: 1088 EISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSG---SMKITETRTSD 1144
Query: 498 EGDYVFAPD--AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPP 555
G Y+ A NVT K++V PPKI + V G ++ + G P P
Sbjct: 1145 SGMYLCVATNIAGNVTQAVKLNVHVPPKI----QRGPKHLKVQVGQRVDIPCNAQGTPLP 1200
Query: 556 KAMWSRGDKA-IMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKV 614
WS+G +++G + S PD TL ID A D+G+Y N AG I +
Sbjct: 1201 VITWSKGGSTMLVDGEHHV---SNPD-GTLSIDQATPSDAGIYTCVATNIAGTDETEITL 1256
Query: 615 KVVDFP-----DPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRL 669
V + P +PP T E + I E P G+P K + +W+
Sbjct: 1257 HVQEPPTVEDLEPPYNTTFQERVANQRI---EFPCPAKGTP----------KPTIKWLHN 1303
Query: 670 NFDLCKETTFEPKKMIEGVAYEVRIFAVN--------AIGISKPSMPSRPFVPLAVTSPP 721
+L T EP I + I +V + +++ R + L V PP
Sbjct: 1304 GREL---TGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKY-NLKVHVPP 1359
Query: 722 TLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEG----STSAKQSDENGEAAYDL 777
+ + VT+ +V + G ++ + + +S Q+ NG
Sbjct: 1360 VIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNG------ 1413
Query: 778 PAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPP 837
K P DA + KA+N AG S+ KY++ +LV PP
Sbjct: 1414 --------------KILKLFRATPEDAGRY-SCKAINIAGTSQ-KYFNIDVLV-----PP 1452
Query: 838 KIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIF 897
I I + + V L +G P P++ W KDG + N+ + ++
Sbjct: 1453 TI-IGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLH 1511
Query: 898 IRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKD 957
++ A R+ G+Y V + I + I P + G NV
Sbjct: 1512 LKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPP---------SIKGGNVT-------T 1555
Query: 958 DGNAAITGYTIQKADKKS--MEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1015
D + I + + + M T + ++ L I Y + +S+
Sbjct: 1556 DISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHI---PRAQVSD 1612
Query: 1016 DATMTKESAVIARDGK------IYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCS 1069
AT T A +A + +Y P+ E PL N + ++ TL C
Sbjct: 1613 SATYTCHVANVAGTAEKSFHVDVYVPPMIEG-------NLATPL-NKQVVIAHSLTLECK 1664
Query: 1070 VRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVE 1129
GNP P +TW+K+ V + + R+ G LEI D G Y C A + G E
Sbjct: 1665 AAGNPSPILTWLKDGVPVKANDNIRI--EAGGKKLEIMSAQEIDRGQYICVATSVAGEKE 1722
Query: 1130 IECKLEVKV 1138
I+ +++V V
Sbjct: 1723 IKYEVDVLV 1731
Score = 95.9 bits (237), Expect = 2e-19
Identities = 192/924 (20%), Positives = 331/924 (35%), Gaps = 162/924 (17%)
Query: 279 PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCST----E 334
P + W+K+G + + G R L I N Q + Y A +E E
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILPGG--RTLQILNAQEDNAGRYSCVATNEAGEMIKHYE 2660
Query: 335 LFVREPPIMVTKQL-------EDTTAYCGERVELECEV-SEDDANVKWFKNGEEIIPGPK 386
+ V PPI+ L ++ + LECE + A++ W+K+G+ + K
Sbjct: 2661 VKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPL----K 2716
Query: 387 SRYRIRVEGKKHILIIEGATKADAAEYSVMTTG--GQSSAKLSVDLKPLKILTPLTD--- 441
S + + H L I+ A +D Y+ + + G+ V+++ L +
Sbjct: 2717 SDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGN 2776
Query: 442 ----------QTVNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIHKLV 489
+ V + I L CE + P W K+G P+ SD++ ++ GR+ L
Sbjct: 2777 MLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRV--LQ 2834
Query: 490 IANALTEDEGDY--VFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEI 547
I A ED G Y V +A +L V V+ PP I D VTV+ +E
Sbjct: 2835 IPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIEC 2894
Query: 548 PISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGE 607
SG P P+ W + + ++E + + L I + D G Y +N AG
Sbjct: 2895 LSSGSPAPRNSWQKDGQPLLEDD---HHKFLSNGRILQILNTQITDIGRYVCVAENTAGS 2951
Query: 608 A--HASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSR 665
A + ++ V V P + +T V +++ + E + P L + K +Q +
Sbjct: 2952 AKKYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCEVSGFP--PPDLSWL---KNEQPIK 3006
Query: 666 WMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLT 725
+ T + + E A+N G SK L V PP++
Sbjct: 3007 LNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKF------SLTVYVPPSIKD 3060
Query: 726 VDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVA 785
DS + + V +R EG++ + + + N A P W
Sbjct: 3061 HDSESLSVVNVR---------------------EGTSVSLECESN---AVPPPVITWYKN 3096
Query: 786 NKDLIDKTKFTI----------TGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIE 835
+ + + T I +D +V +A+N AG + ++ +
Sbjct: 3097 GRMITESTHVEILADGQMLHIKKAEVSDTGQYV-CRAINVAGRDDKNFH------LNVYV 3149
Query: 836 PPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEID-KNQINIRNSETDT 894
PP I P ++ + + V L G P P + W K+ I+ + + +R +
Sbjct: 3150 PPSIEGPE--REVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGS 3207
Query: 895 IIFIRKAERSHSGKY-----DLQVKVDKFVETASIDIQIIDRPGPPQIVKIE---DV--- 943
+ I +++ S SG Y +++ K K+ + IQ+ PP + E DV
Sbjct: 3208 KLQIARSQHSDSGNYTCIASNMEGKAQKYY---FLSIQV-----PPSVAGAEIPSDVSVL 3259
Query: 944 WGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYF 1003
GENV L + N T D K + G
Sbjct: 3260 LGENVELVC-----NANGIPTPLIQWLKDGK-------------------PIASGETERI 3295
Query: 1004 RVFSENMCGLSEDATMTKESAVIARDGK---IYKNPVYEDFDFSEAPMFTQPLV------ 1054
RV + +T+ A+ + GK + NP E+ ++ P +
Sbjct: 3296 RVSANG-------STLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDE 3348
Query: 1055 --NTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPY 1112
+ + + C G P P+I W+KN + + R+ + V + I +
Sbjct: 3349 AEKLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQV--IRIVRAQVS 3406
Query: 1113 DGGTYCCKAVNDLGTVEIECKLEV 1136
D Y C A N G L+V
Sbjct: 3407 DVAVYTCVASNRAGVDNKHYNLQV 3430
Score = 95.1 bits (235), Expect = 3e-19
Identities = 198/896 (22%), Positives = 329/896 (36%), Gaps = 121/896 (13%)
Query: 279 PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTA----GDEKCSTE 334
P ++ W KN Q I+ +T + G R L I +++D EY A G+ K
Sbjct: 2992 PPPDLSWLKNEQPIKLNTNTLIVPGG--RTLQIIRAKVSDGGEYTCIAINQAGESKKKFS 3049
Query: 335 LFVREPPIMVTKQLEDTTAYC---GERVELECEVSEDDANV-KWFKNGEEIIPGPKSRYR 390
L V PP + E + G V LECE + V W+KNG I +
Sbjct: 3050 LTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITES--THVE 3107
Query: 391 IRVEGKKHILIIEGATKADAAEY--SVMTTGGQSSAKLSVDLK-PLKILTPLTDQTVN-L 446
I +G+ +L I+ A +D +Y + G+ +++ P I P + V +
Sbjct: 3108 ILADGQ--MLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETI 3165
Query: 447 GKEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFA 504
+ L C+ + P W KN ++ SD L+V KL IA + D G+Y
Sbjct: 3166 SNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCI 3225
Query: 505 PDAYNVTLPAKVH----VIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWS 560
A N+ A+ + + PP + G + + V+V+ G + L +G P P W
Sbjct: 3226 --ASNMEGKAQKYYFLSIQVPPSVA--GAEIPSDVSVLLGENVELVCNANGIPTPLIQWL 3281
Query: 561 RGDKAIMEG-SGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDF 619
+ K I G + RIR + + STL I A D+G Y N AGE + V
Sbjct: 3282 KDGKPIASGETERIRVSA--NGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVY-- 3337
Query: 620 PDPPVAPTVTEVGDDW--------CIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNF 671
V PT+ D+ +N E A P + + S +RL
Sbjct: 3338 ----VTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRL-- 3391
Query: 672 DLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTD 731
++I V +V AV S + L V +PP + +
Sbjct: 3392 -------LAAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEE 3444
Query: 732 TTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLID 791
TV +GS+++ +G A P+ W+ + L
Sbjct: 3445 ITV-----------------------LKGSSTSMACITDGTPA---PSMAWLRDGQPLGL 3478
Query: 792 KTKFTITGLPTDAKIFVRVKA-------VNAAGASEPKYYSQPILVKEIIEPPKIRIPRH 844
T++ T + +KA ++E S+ ++K ++EPP I
Sbjct: 3479 DAHLTVS---THGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILK-VLEPPHINGSEE 3534
Query: 845 LKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERS 904
++ + V + L G P P++TW KDG + + ++ ++ I A+
Sbjct: 3535 HEEISVI-VNNPLELTCIASGIPAPKMTWMKDGRPLPQTD-QVQTLGGGEVLRISTAQVE 3592
Query: 905 HSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAIT 964
+G+Y + +++ PP I ++ P+D
Sbjct: 3593 DTGRYTCLASSPAGDDDKEYLVRV---HVPPNIAGTDE------------PRDITVLRNR 3637
Query: 965 GYTIQ-KADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKES 1023
T++ K+D T + + R AT ++ Y ++ N L + A T +
Sbjct: 3638 QVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGRYLQI---NNADLGDTANYTCVA 3694
Query: 1024 AVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKN 1083
+ IA GK + + + P + + + L C G P P+ITW K+
Sbjct: 3695 SNIA--GKTTREFI---LTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKD 3749
Query: 1084 KVAIV-DDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1138
+ + RY + N L I+ D G Y C A N GT L+V V
Sbjct: 3750 GAVLAGNHARYSILENG---FLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHV 3802
Score = 92.0 bits (227), Expect = 3e-18
Identities = 205/895 (22%), Positives = 322/895 (35%), Gaps = 141/895 (15%)
Query: 279 PKLEVKWYKNGQEIRPS-TKYIFEHKGCQRILFINNCQMTDDSEYYV----TAGDEKCST 333
P + W K+G + + +Y G L I + +TD Y AG ++
Sbjct: 3740 PTPRITWRKDGAVLAGNHARYSILENG---FLHIQSAHVTDTGRYLCMATNAAGTDRRRI 3796
Query: 334 ELFVREPPIMVTKQLEDTTAYCGERVELECEVSE-DDANVKWFKNGEEI-IPGPKSRYRI 391
+L V PP + + T + L CE + ++ W KNG + + ++ YR+
Sbjct: 3797 DLQVHVPP-SIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRL 3855
Query: 392 RVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLK---PLKILTPLTDQTVNLGK 448
G L+I + D A Y T G K +VDL P I TD V
Sbjct: 3856 LSSGS---LVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPPSIADEPTDFLVTKHA 3912
Query: 449 EICLKCEISENIPGK---WTKNGLPV-QESDRLKVVHKGRIHKLVIANALTEDEGDY--V 502
+ C S +P WTKNG+ + D +++ G I ++A L G Y V
Sbjct: 3913 PAVITCTAS-GVPFPSIHWTKNGIRLLPRGDGYRILSSGAIE--ILATQLNH-AGRYTCV 3968
Query: 503 FAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRG 562
A + +HV +PP I + + VI N + L +G P P W +
Sbjct: 3969 ARNAAGSAHRHVTLHVHEPPVI----QPQPSELHVILNNPILLPCEATGTPSPFITWQK- 4023
Query: 563 DKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDP 622
+ + SGR + S L I A R+D+G Y +N AG A IK+ V
Sbjct: 4024 EGINVNTSGR--NHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNV------ 4075
Query: 623 PVAPTVTEVGDDWCIMNWEPPAY----DGGSP--ILGYFIERKKKQSSRWMRLNFDLCKE 676
V P ++ ++ I +P DG P I + R +S R L+ +
Sbjct: 4076 QVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQI 4135
Query: 677 TTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDT---- 732
+P G A A N G S S VP + S TV+ +
Sbjct: 4136 AFVQP-----GDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPC 4190
Query: 733 ------TVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVAN 786
T + W+ + + A L Y E P + I+ N
Sbjct: 4191 VADGIPTPAINWKKDNVLLANLLGKYTAE----------------------PYGELILEN 4228
Query: 787 KDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLK 846
L D +T A NAAG + + + + P +P +
Sbjct: 4229 VVLEDSGFYTCV-------------ANNAAGED-----THTVSLTVHVLPTFTELPGDVS 4270
Query: 847 QTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHS 906
GE + L G P P+LTW + I + ++ N ++ +I + + S
Sbjct: 4271 LNK----GEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDSV-NGHSELVI--ERVSKEDS 4323
Query: 907 GKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGY 966
G Y V TA + + G VK V+ + W P G AI
Sbjct: 4324 GTY---------VCTAENSVGFVKAIGFVY-VKEPPVFKGDYPSNWIEPL--GGNAILNC 4371
Query: 967 TIQKADKKSMEWFTV---IEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKES 1023
++ +++W IE HR I +L G+ + +E+ + T E+
Sbjct: 4372 EVKGDPTPTIQWNRKGVDIEISHR----IRQLGNGSLAIYGTVNEDAGDYT--CVATNEA 4425
Query: 1024 AVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKN 1083
V+ R + P+ T V T AG LNC G P+P ITW +
Sbjct: 4426 GVVERSMSL---------TLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQ 4476
Query: 1084 KVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1138
+I D R + SN + + +K D + C A N +G+V + + V+V
Sbjct: 4477 GHSISWDDRVNVLSNNSLYIADAQKE---DTSEFECVARNLMGSVLVRVPVIVQV 4528
Score = 89.7 bits (221), Expect = 1e-17
Identities = 161/683 (23%), Positives = 252/683 (36%), Gaps = 115/683 (16%)
Query: 277 ADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVT----AGDEKCS 332
A P + WYK+GQ ++ G L I Q++D Y AG+++
Sbjct: 2700 AIPSASLSWYKDGQPLKSDDHVNIAANG--HTLQIKEAQISDTGRYTCVASNIAGEDELD 2757
Query: 333 TELFVREPP-----------IMVTKQLEDTTAYCGERVELECEV-SEDDANVKWFKNGEE 380
++ ++ PP + + E + L CE + + W+K+G
Sbjct: 2758 FDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHP 2817
Query: 381 IIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPL- 439
+ K + + +L I A DA Y+ + L D++ L + P+
Sbjct: 2818 LTSSDK----VLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVL--VPPII 2871
Query: 440 --------TDQTVNLGKEICLKCEISENIP---GKWTKNGLPVQESDRLKVVHKGRIHKL 488
+ TV + K ++C +S P W K+G P+ E D K + GRI L
Sbjct: 2872 KGANSDLPEEVTVLVNKSALIEC-LSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRI--L 2928
Query: 489 VIANALTEDEGDYVFAPDAYNVTLPAK------VHVIDPPKIILDGLDADNTVTVIAGNK 542
I N D G YV A N AK VHV PP +I G ++N +TV+ N
Sbjct: 2929 QILNTQITDIGRYVCV--AENTAGSAKKYFNLNVHV--PPSVI--GPKSEN-LTVVVNNF 2981
Query: 543 LRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLK 602
+ L +SG PPP W + ++ I + T P TL I A+ D G Y
Sbjct: 2982 ISLTCEVSGFPPPDLSWLKNEQPIKLNT---NTLIVPGGRTLQIIRAKVSDGGEYTCIAI 3038
Query: 603 NEAGEAHASIKVKVVDFPD----PPVAPTVTEVGDDW-----CIMNWEPPAYDGGSPILG 653
N+AGE+ + V P + +V V + C N PP P++
Sbjct: 3039 NQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPP------PVIT 3092
Query: 654 YFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV 713
++ + S + + L KK + A+N G + +V
Sbjct: 3093 WYKNGRMITESTHVEI---LADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYV 3149
Query: 714 PLAVTSPPTLLTVDSVTD---TTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDEN 770
P ++ P + V+++++ T PP I A L + E S S + +
Sbjct: 3150 PPSIEGPEREVIVETISNPVTLTCDATGIPPPTI--AWLKNHKR---IENSDSLEVRILS 3204
Query: 771 GEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILV 830
G + +A D +T A N G ++ KYY I V
Sbjct: 3205 GGSKLQ-------IARSQHSDSGNYTCI-------------ASNMEGKAQ-KYYFLSIQV 3243
Query: 831 KEIIEPPKI---RIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQI-N 886
PP + IP + +GE V LV G P P + W KDG I +
Sbjct: 3244 -----PPSVAGAEIPSDVSVL----LGENVELVCNANGIPTPLIQWLKDGKPIASGETER 3294
Query: 887 IRNSETDTIIFIRKAERSHSGKY 909
IR S + + I A S +GKY
Sbjct: 3295 IRVSANGSTLNIYGALTSDTGKY 3317
Score = 75.1 bits (183), Expect = 4e-13
Identities = 93/343 (27%), Positives = 139/343 (40%), Gaps = 43/343 (12%)
Query: 325 TAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEV-SEDDANVKWFKNGEEIIP 383
+AG + T V EPP ++ + T GER L C + S D N+ W +N ++
Sbjct: 504 SAGTGRAQTFFDVSEPPPVIQVP-NNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRL 562
Query: 384 GPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTT--GGQSSAKLSVDLK-PLKILTPLT 440
+R R L ++ DA EY M + GG S+A + + ++ P K+
Sbjct: 563 AEPARIRTLANLS---LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPK 619
Query: 441 DQTVNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDE 498
+Q+ G E+ + C + K WT N + + S R ++ G L I NA +D
Sbjct: 620 NQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGT---LFIKNAAPKDA 676
Query: 499 GDY------VFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGE 552
G Y D N TL I+ PK+++ + + V G+ +E SG
Sbjct: 677 GIYGCLASNSAGTDKQNSTL----RYIEAPKLMV----VQSELLVALGDITVMECKTSGI 728
Query: 553 PPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASI 612
PPP+ W +GD + + I P L I + D+G Y NEAG A I
Sbjct: 729 PPPQVKWFKGDLELRPSTFLIID---PLLGLLKIQETQDLDAGDYTCVAINEAGRATGKI 785
Query: 613 KVKVVDFPDPPV-----APTVTEVGDDWCIMNWEPPAYDGGSP 650
+D PPV A E+G N P Y G P
Sbjct: 786 ---TLDVGSPPVFIQEPADVSMEIGS-----NVTLPCYVQGYP 820
Score = 69.3 bits (168), Expect = 2e-11
Identities = 93/374 (24%), Positives = 141/374 (37%), Gaps = 47/374 (12%)
Query: 278 DPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYV----TAGDEKCST 333
+P E+ W+K+GQ ++ + G R L I N Q+ Y AG + S
Sbjct: 2506 NPVPEITWHKDGQPLQEDEAHHIISGG--RFLQITNVQVPHTGRYTCLASSPAGHKSRSF 2563
Query: 334 ELFVREPPIMV----TKQLEDTTAYCGERVELECEV-SEDDANVKWFKNGEEIIPGPKSR 388
L V P + ED T L CE S A + WFK+G + +S
Sbjct: 2564 SLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPL----ESN 2619
Query: 389 YRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSA----KLSVDLKPL--------KIL 436
IR+ L I A + +A YS + T ++ V + P+ L
Sbjct: 2620 RNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGL 2679
Query: 437 TPLTDQTVNLGKEICLKCEISENIPG---KWTKNGLPVQESDRLKVVHKGRIHKLVIANA 493
+P + + + + L+CE + IP W K+G P++ D + + G H L I A
Sbjct: 2680 SP-KEVKIKVNNTLTLECE-AYAIPSASLSWYKDGQPLKSDDHVNIAANG--HTLQIKEA 2735
Query: 494 LTEDEGDY--VFAPDAYNVTLPAKVHVIDPPKI--------ILDGLDADNTVTVIAGNKL 543
D G Y V + A L V++ PP +LD VI N +
Sbjct: 2736 QISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPI 2795
Query: 544 RLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKN 603
L + PPP W + + + P L I A+ +D+G Y N
Sbjct: 2796 SLYCETNAAPPPTLTWYKDGHPLTSSD---KVLILPGGRVLQIPRAKVEDAGRYTCVAVN 2852
Query: 604 EAGEAHASIKVKVV 617
EAGE V+V+
Sbjct: 2853 EAGEDSLQYDVRVL 2866
Score = 68.9 bits (167), Expect = 3e-11
Identities = 89/362 (24%), Positives = 148/362 (40%), Gaps = 28/362 (7%)
Query: 277 ADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYV----TAGDEKCS 332
A P + WYKNG+ I ST G ++L I +++D +Y AG + +
Sbjct: 3085 AVPPPVITWYKNGRMITESTHVEILADG--QMLHIKKAEVSDTGQYVCRAINVAGRDDKN 3142
Query: 333 TELFVREPPIMVTKQLEDTTAYCGERVELECEVSE-DDANVKWFKNGEEIIPGPKSRYRI 391
L V PP + + E V L C+ + + W KN + I RI
Sbjct: 3143 FHLNVYVPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRI 3202
Query: 392 RVEGKKHILIIEGATKADAAEYSVMTTGGQSSAK----LSVDLKPLKILTPL-TDQTVNL 446
G K L I + +D+ Y+ + + + A+ LS+ + P + +D +V L
Sbjct: 3203 LSGGSK--LQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLL 3260
Query: 447 GKEICLKCEISENIPG---KWTKNGLPVQ--ESDRLKVVHKGRIHKLVIANALTEDEGDY 501
G+ + L C + IP +W K+G P+ E++R++V G L I ALT D G Y
Sbjct: 3261 GENVELVCN-ANGIPTPLIQWLKDGKPIASGETERIRVSANG--STLNIYGALTSDTGKY 3317
Query: 502 --VFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMW 559
V A ++V P I + +A+ +T++ + +E +G PPP+ W
Sbjct: 3318 TCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLV-DTSINIECRATGTPPPQINW 3376
Query: 560 SRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDF 619
+ + S + I A+ D VY N AG + ++V
Sbjct: 3377 LKNGLPLPLSS---HIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAP 3433
Query: 620 PD 621
P+
Sbjct: 3434 PN 3435
Score = 67.4 bits (163), Expect = 7e-11
Identities = 189/886 (21%), Positives = 319/886 (36%), Gaps = 156/886 (17%)
Query: 309 LFINNCQMTDDSEYYVTAGDE--KCSTELFVR-----EPPIMVTKQLEDTTAYCGERVEL 361
LFI N +D Y A ++ K +E V P I ++ + + G+++ L
Sbjct: 852 LFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVIE--GQQLTL 909
Query: 362 ECEVSEDDA--NVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTG 419
C + + +W KN ++ P +R +G HI E D EY+ + +
Sbjct: 910 PCTLLAGNPIPERRWIKNSAMLLQNPY--ITVRSDGSLHI---ERVQLQDGGEYTCVASN 964
Query: 420 --GQSSAKLSVDLKPLKILTPLTDQTVNL-GKEICLKCEISENIPGK--WTKNGLPVQES 474
G ++ SV + L + + G + L C+ S N W+K G + S
Sbjct: 965 VAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTS 1024
Query: 475 DRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAK----VHVIDPPKIILD--G 528
G L + + E+ G+YV A N AK + V P++ D G
Sbjct: 1025 SAK--FSAGADGSLYVVSPGGEESGEYVCT--ATNTAGYAKRKVQLTVYVRPRVFGDQRG 1080
Query: 529 LDADNTV--TVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVI 586
L D V +V+AG ++ L + PPP W++ + I S R ++ S ++ I
Sbjct: 1081 LSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPR---HTFLPSGSMKI 1137
Query: 587 DIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEV-------------GD 633
DSG+Y N AG ++K+ V P P +V G
Sbjct: 1138 TETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQGT 1197
Query: 634 DWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVR 693
++ W GGS +L ++ + S+ L+ D + +
Sbjct: 1198 PLPVITWS----KGGSTML---VDGEHHVSNPDGTLSID-------------QATPSDAG 1237
Query: 694 IFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYV 753
I+ A I+ + L V PPT+ ++ +TT R V
Sbjct: 1238 IYTCVATNIAGTDETE---ITLHVQEPPTVEDLEPPYNTTFQER---------------V 1279
Query: 754 LEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLI----------DKTKFTITGL-PT 802
E AK + + P W+ ++L D T I + P
Sbjct: 1280 ANQRIEFPCPAKGTPK--------PTIKWLHNGRELTGREPGISILEDGTLLVIASVTPY 1331
Query: 803 DAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIP 862
D ++ V AVN AG +E KY ++ PP I+ + + + + NL
Sbjct: 1332 DNGEYICV-AVNEAGTTERKYN------LKVHVPPVIKDKEQVTNVSV-LLNQLTNLFCE 1383
Query: 863 FQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETA 922
+G P P + W KD ++ ++ I+ I+ + +A +G+Y K + A
Sbjct: 1384 VEGTPSPIIMWYKDNVQVTESS-TIQTVNNGKILKLFRATPEDAGRYSC-----KAINIA 1437
Query: 923 SIDIQI--IDRPGPPQIV------KIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKK 974
+ ID PP I+ ++ V +VAL ++
Sbjct: 1438 GTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALE--------------CQVKGTPFP 1483
Query: 975 SMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGK--I 1032
+ WF + + L G + + N G + T++ + A+D K I
Sbjct: 1484 DIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQ-CTVSNAAGKQAKDIKLTI 1542
Query: 1033 YKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPR 1092
Y P + L+N+ L C RG P P ITW K+ I+ +
Sbjct: 1543 YIPPSIKG---GNVTTDISVLINSL------IKLECETRGLPMPAITWYKDGQPIMSSSQ 1593
Query: 1093 YRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1138
++ ++G L I + D TY C N GT E ++V V
Sbjct: 1594 -ALYIDKGQ-YLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYV 1637
Score = 63.9 bits (154), Expect = 8e-10
Identities = 86/356 (24%), Positives = 139/356 (39%), Gaps = 34/356 (9%)
Query: 279 PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVT----AGDEKCSTE 334
P +VKW+K E+RPST I + +L I Q D +Y AG
Sbjct: 729 PPPQVKWFKGDLELRPSTFLIID--PLLGLLKIQETQDLDAGDYTCVAINEAGRATGKIT 786
Query: 335 LFVREPPIMVTKQLEDTTAYCGERVELECEV-SEDDANVKWFK-NGEEIIPGPKSRYRIR 392
L V PP+ + ++ D + G V L C V + +KW + + I P S I
Sbjct: 787 LDVGSPPVFI-QEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSIS 845
Query: 393 V--EGKKHILIIEGATKAD---AAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLG 447
G IL + + K AE +++ ++ + PL ++P + G
Sbjct: 846 QLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVIE-G 904
Query: 448 KEICLKCEISENIP---GKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFA 504
+++ L C + P +W KN + ++ + V G +H I +D G+Y
Sbjct: 905 QQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGSLH---IERVQLQDGGEYTCV 961
Query: 505 PD----AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWS 560
N T VHV+ P I ++ I G + L SG P P +WS
Sbjct: 962 ASNVAGTNNKTTSVVVHVL--PTI----QHGQQILSTIEGIPVTLPCKASGNPKPSVIWS 1015
Query: 561 RGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKV 616
+ + I S + + D S V+ ++SG Y N AG A +++ V
Sbjct: 1016 KKGELISTSSAKFSAGA--DGSLYVVS-PGGEESGEYVCTATNTAGYAKRKVQLTV 1068
Score = 57.4 bits (137), Expect = 8e-08
Identities = 34/83 (40%), Positives = 40/83 (48%), Gaps = 3/83 (3%)
Query: 1045 EAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTL 1104
E P T N G ++ CS G PKPKI W N + IV RYRM S+ TL
Sbjct: 610 EPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDG---TL 666
Query: 1105 EIRKPSPYDGGTYCCKAVNDLGT 1127
I+ +P D G Y C A N GT
Sbjct: 667 FIKNAAPKDAGIYGCLASNSAGT 689
Score = 46.6 bits (109), Expect = 1e-04
Identities = 68/311 (21%), Positives = 109/311 (35%), Gaps = 48/311 (15%)
Query: 839 IRIPRHLK---QTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTI 895
+ +P ++K Q+ + + ++ L +G P P +TW+KDGA + N E +
Sbjct: 3709 VNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILE-NGF 3767
Query: 896 IFIRKAERSHSGKYDLQVKVDKFVETASIDIQI----IDRPGPPQIVKIEDVWGENVALT 951
+ I+ A + +G+Y + ID+Q+ PGP + I +V
Sbjct: 3768 LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEA 3827
Query: 952 WTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSEN-- 1009
PK N G+ + V N+ +R+ S
Sbjct: 3828 TGIPKPSINWRKNGHLLN--------------------------VDQNQNSYRLLSSGSL 3861
Query: 1010 -MCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNC 1068
+ S D T T E V G + D P + A + C
Sbjct: 3862 VIISPSVDDTATYECTVTNGAGDDKRT---VDLTVQVPPSIADEPTDFLVTKHAPAVITC 3918
Query: 1069 SVRGNPKPKITWMKNKVAIVDDPR---YRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDL 1125
+ G P P I W KN + ++ PR YR+ S+ + EI G Y C A N
Sbjct: 3919 TASGVPFPSIHWTKNGIRLL--PRGDGYRILSSGAI---EILATQLNHAGRYTCVARNAA 3973
Query: 1126 GTVEIECKLEV 1136
G+ L V
Sbjct: 3974 GSAHRHVTLHV 3984
Score = 45.1 bits (105), Expect = 4e-04
Identities = 74/347 (21%), Positives = 130/347 (37%), Gaps = 52/347 (14%)
Query: 812 AVNAAGAS----EPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKP 867
A N AG E K Y PI+ K + P + P+ +K +V + L P
Sbjct: 2648 ATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLS-PKEVKI----KVNNTLTLECEAYAIP 2702
Query: 868 RPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQ 927
L+W KDG + K+ ++ + + I++A+ S +G+Y + D+
Sbjct: 2703 SASLSWYKDGQPL-KSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVN 2761
Query: 928 IIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHR 987
I PP K+ ++ GN TG + + K + I Y
Sbjct: 2762 I---QVPPSFQKLWEI---------------GNMLDTG---RNGEAKDVIINNPISLYCE 2800
Query: 988 TSA----TITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGK---IYKNPVYED 1040
T+A T+T G+ S+ + L + A + G+ + N ED
Sbjct: 2801 TNAAPPPTLTWYKDGHPL---TSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGED 2857
Query: 1041 FDFSEAPMFTQPLVN---------TYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDP 1091
+ + P++ + +A + C G+P P+ +W K+ +++D
Sbjct: 2858 SLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDD 2917
Query: 1092 RYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1138
++ SN + L+I D G Y C A N G+ + L V V
Sbjct: 2918 HHKFLSNGRI--LQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHV 2962
Score = 45.1 bits (105), Expect = 4e-04
Identities = 81/353 (22%), Positives = 137/353 (38%), Gaps = 61/353 (17%)
Query: 802 TDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVI 861
TD +V V A N AG+++ KY++ + V PP + P+ T + V ++L
Sbjct: 2936 TDIGRYVCV-AENTAGSAK-KYFNLNVHV-----PPSVIGPKSENLTVV--VNNFISLTC 2986
Query: 862 PFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVET 921
G P P+L+W K+ I N T+T+I G LQ+ K +
Sbjct: 2987 EVSGFPPPDLSWLKNEQPIKLN--------TNTLIV--------PGGRTLQIIRAKVSDG 3030
Query: 922 ASIDIQIIDRPGPPQIVKIEDVWGENVALT-WTPP--KDDGNAAITGYTIQKADKKSMEW 978
I++ G + + +LT + PP KD + +++ +++ S+E
Sbjct: 3031 GEYTCIAINQAGESK---------KKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLEC 3081
Query: 979 FT------VIEHYHR----TSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIA- 1027
+ VI Y T +T E++ + +E +S+ + +A
Sbjct: 3082 ESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKKAE----VSDTGQYVCRAINVAG 3137
Query: 1028 RDGKIYKNPVY--EDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKV 1085
RD K + VY + E + + + N TL C G P P I W+KN
Sbjct: 3138 RDDKNFHLNVYVPPSIEGPEREVIVETISNP-------VTLTCDATGIPPPTIAWLKNHK 3190
Query: 1086 AIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1138
I + + G L+I + D G Y C A N G + L ++V
Sbjct: 3191 RIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQV 3243
Score = 44.7 bits (104), Expect = 5e-04
Identities = 66/305 (21%), Positives = 110/305 (36%), Gaps = 33/305 (10%)
Query: 835 EPPKIRI-PRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETD 893
EPPK+ + P++ T G V+++ G P+P++ W + I + S D
Sbjct: 610 EPPKVTVMPKNQSFTG----GSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTS--D 663
Query: 894 TIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWT 953
+FI+ A +G Y + + ++ I+ P K+ V E +
Sbjct: 664 GTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAP------KLMVVQSELLVAL-- 715
Query: 954 PPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL 1013
G+ + ++WF ++ I + ++G E
Sbjct: 716 -----GDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLG----LLKIQETQDLD 766
Query: 1014 SEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGN 1073
+ D T + GKI D P+F Q + G N TL C V+G
Sbjct: 767 AGDYTCVAINEAGRATGKI-------TLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGY 819
Query: 1074 PKPKITWMK-NKVAIVDDP-RYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIE 1131
P+P I W + + + I P S L I D GTY C+A N G ++ E
Sbjct: 820 PEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSE 879
Query: 1132 CKLEV 1136
+ V
Sbjct: 880 TTVTV 884
Score = 42.7 bits (99), Expect = 0.002
Identities = 45/180 (25%), Positives = 73/180 (40%), Gaps = 15/180 (8%)
Query: 452 LKCEISENIPG--KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY--VFAPDA 507
+ C + +P + +NG+ + LK + L IA DEG Y + A
Sbjct: 449 IPCSVDSLLPFTLSFVRNGVTLGVDQYLK---ESASVNLDIAKVTLSDEGFYECIAVSSA 505
Query: 508 YNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAI- 566
V +PP +I N VTV G + L I W R D+ +
Sbjct: 506 GTGRAQTFFDVSEPPPVI----QVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVR 561
Query: 567 MEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAP 626
+ RIRT + + +L + + +D+G YH + +E G + AS+ + V + P V P
Sbjct: 562 LAEPARIRTLA---NLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMP 618
Score = 41.2 bits (95), Expect = 0.006
Identities = 63/339 (18%), Positives = 126/339 (37%), Gaps = 54/339 (15%)
Query: 807 FVRVKAVNAAGASEPKYY---SQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPF 863
F AV++AG + + S+P PP I++P ++ T GE L
Sbjct: 496 FYECIAVSSAGTGRAQTFFDVSEP--------PPVIQVPNNVTVT----PGERAVLTCLI 543
Query: 864 QGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETAS 923
LTW+++ ++ + + + + ++ + + +G+Y V + AS
Sbjct: 544 ISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAAS 603
Query: 924 IDIQIIDRPGPPQIVKIED-VWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVI 982
+ + + + P + K + G V++ + TGY K + W
Sbjct: 604 VFLTVQEPPKVTVMPKNQSFTGGSEVSIM---------CSATGYP-----KPKIAW---- 645
Query: 983 EHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYED-- 1040
T+ ++ I + +R+ S+ + A K++ + G + N D
Sbjct: 646 --------TVNDMFIVGSHRYRMTSDGTLFIKNAAP--KDAGIY---GCLASNSAGTDKQ 692
Query: 1041 ---FDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFS 1097
+ EAP G + C G P P++ W K + + P +
Sbjct: 693 NSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLEL--RPSTFLII 750
Query: 1098 NQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
+ + L+I++ D G Y C A+N+ G + L+V
Sbjct: 751 DPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDV 789
>gi|144226847 obscurin-like 1 [Homo sapiens]
Length = 1896
Score = 116 bits (291), Expect = 1e-25
Identities = 96/368 (26%), Positives = 159/368 (43%), Gaps = 12/368 (3%)
Query: 269 RVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGD 328
RV EL P EV+W K+G+E+ S + + + R L + Q+ D EY D
Sbjct: 915 RVVLTCELCRPWAEVRWTKDGEEVVESPALLLQKEDTVRRLVLPAVQLEDSGEYLCEIDD 974
Query: 329 EKCSTELFVREPPIMVTKQLEDTT--AYCGERVELECEVSEDDANVKWFKNGEEIIPGPK 386
E S + V EPP+ + ++ T A E V L CE+S +DA V+W+K+G E+
Sbjct: 975 ESASFTVTVTEPPVRIIYPRDEVTLIAVTLECVVLMCELSREDAPVRWYKDGLEV--EES 1032
Query: 387 SRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLT---DQT 443
+ +G + L++ A D E+ + ++V P +I+ P D
Sbjct: 1033 EALVLERDGPRCRLVLPAAQPEDGGEFVCDAGDDSAFFTVTVTAPPERIVHPAARSLDLH 1092
Query: 444 VNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV 502
+ L+CE++ +W K+GL V+ SD L++ +G L + +A ED G+YV
Sbjct: 1093 FGAPGRVELRCEVAPAGSQVRWYKDGLEVEASDALQLGAEGPTRTLTLPHAQPEDAGEYV 1152
Query: 503 FAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRG 562
+ + + V + +PP L + + V G + L +S P +WS
Sbjct: 1153 C--ETRHEAITFNVILAEPPVQFLALETTPSPLCVAPGEPVVLSCELSRAGAP-VVWSHN 1209
Query: 563 DKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDP 622
+ + EG G + + L I A +G+Y G S V+V + P
Sbjct: 1210 GRPVQEGEG-LELHAEGPRRVLCIQAAGPAHAGLYTCQSGAAPGAPSLSFTVQVAEPPVR 1268
Query: 623 PVAPTVTE 630
VAP +
Sbjct: 1269 VVAPEAAQ 1276
Score = 116 bits (291), Expect = 1e-25
Identities = 130/532 (24%), Positives = 212/532 (39%), Gaps = 37/532 (6%)
Query: 104 SKAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHES- 162
S G+ +Q E E H+ + I A AG Y C+ S SF ++V E
Sbjct: 1207 SHNGRPVQEGEGLELHAEGPRRVLCIQAAGPAHAGLYTCQSGAAPGAPSLSFTVQVAEPP 1266
Query: 163 ------------TGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVK-QQEEEPQVD 209
+TP D+ SG G D L + V+ +Q QV
Sbjct: 1267 VRVVAPEAAQTRVRSTPGGDLELVVHLSGPGGPVRWYKDGERLASQGRVQLEQAGARQVL 1326
Query: 210 VWELLKNAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGR 269
+ ++ EY A Q R+ + EE L P V +G
Sbjct: 1327 RVQGARSGDAGEYLCDAPQDS---------RIFLVSVEEPLLVKLVSELTPL-TVHEGDD 1376
Query: 270 VRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDE 329
F E++ P +V W +NG + P + G RIL + CQ+ D + AG
Sbjct: 1377 ATFRCEVSPPDADVTWLRNGAVVTPGPQVEMAQNGSSRILTLRGCQLGDAGTVTLRAGST 1436
Query: 330 KCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDA--NVKWFKNGEEIIPGPKS 387
S L VRE ++ ++L+D A G+ V LE E A V+W + G+ + S
Sbjct: 1437 ATSARLHVRETELLFLRRLQDVRAEEGQDVCLEVETGRVGAAGAVRWVRGGQPL--PHDS 1494
Query: 388 RYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLG 447
R + +G H L I G AD Y + ++ A+LSV + L++L PL D T++ G
Sbjct: 1495 RLSMAQDGHIHRLFIHGVILADQGTYGCESHHDRTLARLSVRPRQLRVLRPLEDVTISEG 1554
Query: 448 KEICLKCEIS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPD 506
+ E+S E + G+W + G+ + + + G H+LV+ D G F D
Sbjct: 1555 GSATFQLELSQEGVTGEWARGGVQLYPGPKCHIHSDGHRHRLVLNGLGLADSGCVSFTAD 1614
Query: 507 AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAI 566
++ A++ V + P I+ G + + V G+ E +S + W + A+
Sbjct: 1615 --SLRCAARLIVREVPVTIVRG---PHDLEVTEGDTATFECELS-QALADVTWEKDGNAL 1668
Query: 567 MEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKN-EAGEAHASIKVKVV 617
S R+R ++ L + D+G Y + AG +++ + V
Sbjct: 1669 TP-SPRLRLQALGTRRLLQLRRCGPSDAGTYSCAVGTARAGPVRLTVRERTV 1719
Score = 113 bits (283), Expect = 9e-25
Identities = 83/342 (24%), Positives = 146/342 (42%), Gaps = 22/342 (6%)
Query: 264 VDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYY 323
+ +GG F +EL+ + +W + G ++ P K G + L +N + D
Sbjct: 1551 ISEGGSATFQLELSQEGVTGEWARGGVQLYPGPKCHIHSDGHRHRLVLNGLGLADSGCVS 1610
Query: 324 VTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIP 383
TA +C+ L VRE P+ + + D G+ ECE+S+ A+V W K+G + P
Sbjct: 1611 FTADSLRCAARLIVREVPVTIVRGPHDLEVTEGDTATFECELSQALADVTWEKDGNALTP 1670
Query: 384 GPKSRYRIRVEGKKHILIIEGATKADAAEYS-VMTTGGQSSAKLSVDLKPLKILTPLTDQ 442
P R R++ G + +L + +DA YS + T +L+V + + +L+ L
Sbjct: 1671 SP--RLRLQALGTRRLLQLRRCGPSDAGTYSCAVGTARAGPVRLTVRERTVAVLSELRSV 1728
Query: 443 TVNLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 501
+ G +C +SE G+W G P++ R+++ +G+ H LV++ ED G+
Sbjct: 1729 SAREGDGATFECTVSEVETTGRWELGGRPLRPGARVRIRQEGKKHILVLSELRAEDAGEV 1788
Query: 502 VFAPDAYNVTLPAKVHVI------DPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPP 555
F +V + PP+ TV+ G + LE+ +S
Sbjct: 1789 RFQAGPAQSLALLEVEALPLQMCRHPPR----------EKTVLVGRRAVLEVTVS-RSGG 1837
Query: 556 KAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVY 597
W R + G + S+ + +LVI +D G Y
Sbjct: 1838 HVCWLREGAELCPGD-KYEMRSHGPTHSLVIHDVRPEDQGTY 1878
Score = 112 bits (280), Expect = 2e-24
Identities = 75/243 (30%), Positives = 115/243 (47%), Gaps = 7/243 (2%)
Query: 263 QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 322
+V +G F EL+ +V W K+G + PS + + G +R+L + C +D Y
Sbjct: 1639 EVTEGDTATFECELSQALADVTWEKDGNALTPSPRLRLQALGTRRLLQLRRCGPSDAGTY 1698
Query: 323 YVTAGDEKCS-TELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEI 381
G + L VRE + V +L +A G+ EC VSE + +W G +
Sbjct: 1699 SCAVGTARAGPVRLTVRERTVAVLSELRSVSAREGDGATFECTVSEVETTGRWELGGRPL 1758
Query: 382 IPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILT-PLT 440
PG +R RIR EGKKHIL++ DA E QS A L V+ PL++ P
Sbjct: 1759 RPG--ARVRIRQEGKKHILVLSELRAEDAGEVRFQAGPAQSLALLEVEALPLQMCRHPPR 1816
Query: 441 DQTVNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDE 498
++TV +G+ L+ +S + G W + G + D+ ++ G H LVI + ED+
Sbjct: 1817 EKTVLVGRRAVLEVTVSRS-GGHVCWLREGAELCPGDKYEMRSHGPTHSLVIHDVRPEDQ 1875
Query: 499 GDY 501
G Y
Sbjct: 1876 GTY 1878
Score = 108 bits (270), Expect = 3e-23
Identities = 92/328 (28%), Positives = 155/328 (47%), Gaps = 11/328 (3%)
Query: 283 VKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPP- 341
V+WYK+GQE+ S + E++G R L + Q +D E+ AGDE + + +
Sbjct: 838 VRWYKDGQEVEESDFVVLENEGPHRRLVLPATQPSDGGEFQCVAGDECAYFTVTITDVSS 897
Query: 342 -IMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHIL 400
I+ A ERV L CE+ A V+W K+GEE++ P ++ E L
Sbjct: 898 WIVYPSGKVYVAAVRLERVVLTCELCRPWAEVRWTKDGEEVVESP--ALLLQKEDTVRRL 955
Query: 401 IIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEIC--LKCEIS- 457
++ D+ EY +S ++V P++I+ P + T+ C L CE+S
Sbjct: 956 VLPAVQLEDSGEYLCEIDDESASFTVTVTEPPVRIIYPRDEVTLIAVTLECVVLMCELSR 1015
Query: 458 ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVH 517
E+ P +W K+GL V+ES+ L + G +LV+ A ED G++V DA + + V
Sbjct: 1016 EDAPVRWYKDGLEVEESEALVLERDGPRCRLVLPAAQPEDGGEFVC--DAGDDSAFFTVT 1073
Query: 518 VIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTES 577
V PP+ I+ A ++ + G R+E+ P + D +E S ++ +
Sbjct: 1074 VTAPPERIVH--PAARSLDLHFGAPGRVELRCEVAPAGSQVRWYKDGLEVEASDALQLGA 1131
Query: 578 YPDSSTLVIDIAERDDSGVYHINLKNEA 605
+ TL + A+ +D+G Y ++EA
Sbjct: 1132 EGPTRTLTLPHAQPEDAGEYVCETRHEA 1159
Score = 87.0 bits (214), Expect = 9e-17
Identities = 86/365 (23%), Positives = 149/365 (40%), Gaps = 20/365 (5%)
Query: 269 RVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGD 328
RV EL+ WYK+GQ++ S + + G + L + ++ D E+
Sbjct: 733 RVVLTCELSRVDFPATWYKDGQKVEESELLVVKMDGRKHRLILPEAKVQDSGEFECRTEG 792
Query: 329 EKCSTELFVREPPIMVTKQLED--TTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPK 386
+ V++PP+ + E A E V L CEV +DA V+W+K+G+E+
Sbjct: 793 VSAFFGVTVQDPPVHIVDPREHVFVHAITSECVMLACEVDREDAPVRWYKDGQEV--EES 850
Query: 387 SRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNL 446
+ EG L++ +D E+ + G A +V + + V +
Sbjct: 851 DFVVLENEGPHRRLVLPATQPSDGGEFQCV--AGDECAYFTVTITDVSSWIVYPSGKVYV 908
Query: 447 G----KEICLKCEISEN-IPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 501
+ + L CE+ +WTK+G V ES L + + + +LV+ ED G+Y
Sbjct: 909 AAVRLERVVLTCELCRPWAEVRWTKDGEEVVESPALLLQKEDTVRRLVLPAVQLEDSGEY 968
Query: 502 VFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSR 561
+ D + + V V +PP I+ D + T+ + + L +S E P W +
Sbjct: 969 LCEIDDESASF--TVTVTEPPVRIIYPRD-EVTLIAVTLECVVLMCELSREDAP-VRWYK 1024
Query: 562 GDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPD 621
+ E + P LV+ A+ +D G + +AG+ A V V P+
Sbjct: 1025 DGLEVEESEALVLERDGP-RCRLVLPAAQPEDGGEFVC----DAGDDSAFFTVTVTAPPE 1079
Query: 622 PPVAP 626
V P
Sbjct: 1080 RIVHP 1084
Score = 86.7 bits (213), Expect = 1e-16
Identities = 85/358 (23%), Positives = 145/358 (40%), Gaps = 21/358 (5%)
Query: 268 GRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAG 327
GRV E+A +V+WYK+G E+ S +G R L + + Q D EY
Sbjct: 1097 GRVELRCEVAPAGSQVRWYKDGLEVEASDALQLGAEGPTRTLTLPHAQPEDAGEYVCETR 1156
Query: 328 DEKCSTELFVREPPIMVTKQLEDTTAYC---GERVELECEVSEDDANVKWFKNGEEIIPG 384
E + + + EPP+ + C GE V L CE+S A V W NG + G
Sbjct: 1157 HEAITFNVILAEPPVQFLALETTPSPLCVAPGEPVVLSCELSRAGAPVVWSHNGRPVQEG 1216
Query: 385 PKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLK----PLKILTPLT 440
+ EG + +L I+ A A A Y+ + + LS ++ P++++ P
Sbjct: 1217 --EGLELHAEGPRRVLCIQAAGPAHAGLYTCQSGAAPGAPSLSFTVQVAEPPVRVVAPEA 1274
Query: 441 DQT---VNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTE 496
QT G ++ L +S P +W K+G + R+++ G L + A +
Sbjct: 1275 AQTRVRSTPGGDLELVVHLSGPGGPVRWYKDGERLASQGRVQLEQAGARQVLRVQGARSG 1334
Query: 497 DEGDYVF-APDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPP 555
D G+Y+ AP + L V V +P +++ + +TV G+ +S P
Sbjct: 1335 DAGEYLCDAPQDSRIFL---VSVEEP--LLVKLVSELTPLTVHEGDDATFRCEVS-PPDA 1388
Query: 556 KAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIK 613
W R + G ++ S L + + D+G + + A A ++
Sbjct: 1389 DVTWLRNGAVVTPGP-QVEMAQNGSSRILTLRGCQLGDAGTVTLRAGSTATSARLHVR 1445
Score = 84.7 bits (208), Expect = 4e-16
Identities = 80/305 (26%), Positives = 126/305 (41%), Gaps = 32/305 (10%)
Query: 340 PPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEI--------IPGPKSRYRI 391
P + LED Y GE ++S WF NGEE+ + RYRI
Sbjct: 614 PTARLVAGLEDVQVYDGEDAVFSLDLSTIIQGT-WFLNGEELKSNEPEGQVEPGALRYRI 672
Query: 392 RVEGKKHILIIEGATKADA-AEYSVMTTGGQSSAKLSVDLKPLKILTPL--TDQTVNLGK 448
+G +H LI+ D+ A G Q SA L++ P+ IL+P T +
Sbjct: 673 EQKGLQHRLILHAVKHQDSGALVGFSCPGVQDSAALTIQESPVHILSPQDRVSLTFTTSE 732
Query: 449 EICLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDA 507
+ L CE+S + P W K+G V+ES+ L V GR H+L++ A +D G++ +
Sbjct: 733 RVVLTCELSRVDFPATWYKDGQKVEESELLVVKMDGRKHRLILPEAKVQDSGEFECRTEG 792
Query: 508 ----YNVTL-PAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRG 562
+ VT+ VH++DP + + V I + L + E P + G
Sbjct: 793 VSAFFGVTVQDPPVHIVDPREHVF--------VHAITSECVMLACEVDREDAPVRWYKDG 844
Query: 563 DKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDP 622
+ +E S + E+ LV+ + D G + AG+ A V + D
Sbjct: 845 QE--VEESDFVVLENEGPHRRLVLPATQPSDGGEFQC----VAGDECAYFTVTITDVSSW 898
Query: 623 PVAPT 627
V P+
Sbjct: 899 IVYPS 903
Score = 63.2 bits (152), Expect = 1e-09
Identities = 63/257 (24%), Positives = 108/257 (42%), Gaps = 15/257 (5%)
Query: 256 KILDPAYQVDKGGRVRF-VVELADPKLEVKWYKNGQEIRPSTKYI-FEHKGCQRILFINN 313
K + V++G +F + P+ E++W+ G+ + P + + + + +L +
Sbjct: 249 KCAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLY 308
Query: 314 CQMTDDSEYYV----TAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDD 369
CQ D Y +AG + +L V+EP + T+ L+D LEC+V
Sbjct: 309 CQAKDRGLYVCAARNSAGQTLSAVQLHVKEPRLRFTRPLQDVEGREHGIAVLECKVPNSR 368
Query: 370 ANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGG-QSSAKLSV 428
WF+ + ++P K Y EG LII D Y G ++ A ++V
Sbjct: 369 IPTAWFREDQRLLPCRK--YEQIEEGTVRRLIIHRLKADDDGIYLCEMRGRVRTVANVTV 426
Query: 429 DLKPLKILTPLTDQTVNLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHK 487
LK L D V G+ L E E + G+W+++G +E + G +H
Sbjct: 427 KGPILKRLPRKLD--VLEGENAVLLVETLEAGVEGRWSRDG---EELPVICQSSSGHMHA 481
Query: 488 LVIANALTEDEGDYVFA 504
LV+ ED G+ F+
Sbjct: 482 LVLPGVTREDAGEVTFS 498
Score = 58.2 bits (139), Expect = 4e-08
Identities = 71/325 (21%), Positives = 131/325 (40%), Gaps = 31/325 (9%)
Query: 356 GERVELECEV-SEDDANVKWFKNGEEIIPGPKS-RYRIRVEGKKHILIIEGATKADAAEY 413
G+ + C V + + ++W G ++P + YR R G +L + D Y
Sbjct: 260 GKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGG--FVLKVLYCQAKDRGLY 317
Query: 414 --SVMTTGGQ--SSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEI-SENIPGKWTKNG 468
+ + GQ S+ +L V L+ PL D L+C++ + IP W +
Sbjct: 318 VCAARNSAGQTLSAVQLHVKEPRLRFTRPLQDVEGREHGIAVLECKVPNSRIPTAWFRED 377
Query: 469 LPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF-----APDAYNVTLPAKVHVIDPPK 523
+ + + + +G + +L+I +D+G Y+ NVT+ + P K
Sbjct: 378 QRLLPCRKYEQIEEGTVRRLIIHRLKADDDGIYLCEMRGRVRTVANVTVKGPILKRLPRK 437
Query: 524 IILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSST 583
LD L+ +N V ++ LE + G WSR + + I S
Sbjct: 438 --LDVLEGENAVLLVE----TLEAGVEGR------WSRDGEELPV----ICQSSSGHMHA 481
Query: 584 LVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPP 643
LV+ R+D+G +L N +K P PP+ + + + ++ W+PP
Sbjct: 482 LVLPGVTREDAGEVTFSLGNSRTTTLLRVKCVKHSPPGPPILAEMFKGHKNTVLLTWKPP 541
Query: 644 AYDGGSPILGYFIERKKKQSSRWMR 668
+P + Y +ER++ S W++
Sbjct: 542 EPAPETPFI-YRLERQEVGSEDWIQ 565
Score = 52.4 bits (124), Expect = 2e-06
Identities = 31/94 (32%), Positives = 51/94 (54%), Gaps = 3/94 (3%)
Query: 535 VTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDS 594
V V++G + L+ + GEPPP +W +G + + S R+ + L++ A D+
Sbjct: 21 VRVVSGAEAELKCVVLGEPPPVVVWEKGGQQ-LAASERLSFPADGAEHGLLLTAALPTDA 79
Query: 595 GVYHINLKNEAGEAHASIKVKVVDFP--DPPVAP 626
GVY +N AGEA+A+ V V++ P DP + P
Sbjct: 80 GVYVCRARNAAGEAYAAAAVTVLEPPASDPELQP 113
Score = 44.3 bits (103), Expect = 7e-04
Identities = 36/155 (23%), Positives = 64/155 (41%), Gaps = 8/155 (5%)
Query: 275 ELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYV-TAGDEKCST 333
++ + ++ W++ Q + P KY +G R L I+ + DD Y G +
Sbjct: 363 KVPNSRIPTAWFREDQRLLPCRKYEQIEEGTVRRLIIHRLKADDDGIYLCEMRGRVRTVA 422
Query: 334 ELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRV 393
+ V+ P + + D GE L E E +W ++GEE+ +S
Sbjct: 423 NVTVKGPILKRLPRKLDVLE--GENAVLLVETLEAGVEGRWSRDGEELPVICQSS----- 475
Query: 394 EGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSV 428
G H L++ G T+ DA E + +++ L V
Sbjct: 476 SGHMHALVLPGVTREDAGEVTFSLGNSRTTTLLRV 510
Score = 43.5 bits (101), Expect = 0.001
Identities = 70/314 (22%), Positives = 114/314 (36%), Gaps = 56/314 (17%)
Query: 356 GERVELECEV-SEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEY- 413
G EL+C V E V W K G+++ R +G +H L++ A DA Y
Sbjct: 26 GAEAELKCVVLGEPPPVVVWEKGGQQL--AASERLSFPADGAEHGLLLTAALPTDAGVYV 83
Query: 414 -SVMTTGGQSSAKLSV----------DLKPLK--------------ILTPLTDQTVNLGK 448
G++ A +V +L+P + LT Q V G
Sbjct: 84 CRARNAAGEAYAAAAVTVLEPPASDPELQPAERPLPSPGSGEGAPVFLTGPRSQWVLRGA 143
Query: 449 EICLKCEISENIPGK---WTKNGLPVQE--SDRLKVVHKGRIHK-------LVIANALTE 496
E+ L C +P W K+G+ + E + GR L I A
Sbjct: 144 EVVLTCRAG-GLPEPTLYWEKDGMALDEVWDSSHFALQPGRAEDGPGASLALRILAARLP 202
Query: 497 DEGDYV-FAPDAYN---------VTLPAKVHVIDP---PKIILDGLD-ADNTVTVIAGNK 542
D G YV A +A+ V P + DP P +++ L A T V G
Sbjct: 203 DSGVYVCHARNAHGHAQAGALLQVHQPPESPPADPDEAPAPVVEPLKCAPKTFWVNEGKH 262
Query: 543 LRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLK 602
+ + G+P P+ W + ++ R+ L + + D G+Y +
Sbjct: 263 AKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGLYVCAAR 322
Query: 603 NEAGEAHASIKVKV 616
N AG+ +++++ V
Sbjct: 323 NSAGQTLSAVQLHV 336
Score = 38.1 bits (87), Expect = 0.048
Identities = 24/78 (30%), Positives = 35/78 (44%), Gaps = 1/78 (1%)
Query: 1061 GYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQ-GVCTLEIRKPSPYDGGTYCC 1119
G +A C V G P+P+I W ++ D R M+ ++ G L++ D G Y C
Sbjct: 260 GKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGLYVC 319
Query: 1120 KAVNDLGTVEIECKLEVK 1137
A N G +L VK
Sbjct: 320 AARNSAGQTLSAVQLHVK 337
Score = 37.7 bits (86), Expect = 0.063
Identities = 20/68 (29%), Positives = 28/68 (41%)
Query: 1059 IAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYC 1118
++G A L C V G P P + W K + R ++ L + P D G Y
Sbjct: 24 VSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLLLTAALPTDAGVYV 83
Query: 1119 CKAVNDLG 1126
C+A N G
Sbjct: 84 CRARNAAG 91
Score = 35.4 bits (80), Expect = 0.31
Identities = 68/342 (19%), Positives = 125/342 (36%), Gaps = 48/342 (14%)
Query: 799 GLPTDAKIFVRVKAVNAAGASEPKYYS--------QPIL--VKEIIEPPKIRIPRHLKQT 848
GL A+ RV + AAG + Y+ P L ++ EPP + QT
Sbjct: 1218 GLELHAEGPRRVLCIQAAGPAHAGLYTCQSGAAPGAPSLSFTVQVAEPPVRVVAPEAAQT 1277
Query: 849 YIRRV-GEAVNLVIPFQGKPRPELTWKKDGAEI-DKNQINIRNSETDTIIFIRKAERSHS 906
+R G + LV+ G P + W KDG + + ++ + + ++ ++ A +
Sbjct: 1278 RVRSTPGGDLELVVHLSGPGGP-VRWYKDGERLASQGRVQLEQAGARQVLRVQGARSGDA 1336
Query: 907 GKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGY 966
G+Y D + S++ P +VK+ E LT +G+ A
Sbjct: 1337 GEYLCDAPQDSRIFLVSVE--------EPLLVKLVS---ELTPLT----VHEGDDATFRC 1381
Query: 967 TIQKADKKSMEWFTVIEHYHRTSATIT---ELVIGNEYYFRVFSENMCGLSEDATMTKES 1023
+ D + W R A +T ++ + R+ + C L + T+T +
Sbjct: 1382 EVSPPDA-DVTWL-------RNGAVVTPGPQVEMAQNGSSRILTLRGCQLGDAGTVTLRA 1433
Query: 1024 AVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSV-RGNPKPKITWMK 1082
A +++ +F + L + A G + L R + W++
Sbjct: 1434 GSTATSARLHVRET--------ELLFLRRLQDVRAEEGQDVCLEVETGRVGAAGAVRWVR 1485
Query: 1083 NKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVND 1124
+ D R M + + L I D GTY C++ +D
Sbjct: 1486 GGQPLPHDSRLSMAQDGHIHRLFIHGVILADQGTYGCESHHD 1527
Score = 35.0 bits (79), Expect = 0.41
Identities = 19/59 (32%), Positives = 28/59 (47%), Gaps = 1/59 (1%)
Query: 1061 GYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCC 1119
G AT C + +TW K+ A+ PR R+ + L++R+ P D GTY C
Sbjct: 1643 GDTATFECEL-SQALADVTWEKDGNALTPSPRLRLQALGTRRLLQLRRCGPSDAGTYSC 1700
Score = 34.3 bits (77), Expect = 0.69
Identities = 15/47 (31%), Positives = 23/47 (48%)
Query: 1078 ITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVND 1124
+ W++ + +Y M S+ +L I P D GTYCC+A D
Sbjct: 1839 VCWLREGAELCPGDKYEMRSHGPTHSLVIHDVRPEDQGTYCCQAGQD 1885
Score = 32.7 bits (73), Expect = 2.0
Identities = 21/77 (27%), Positives = 32/77 (41%), Gaps = 5/77 (6%)
Query: 1061 GYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCK 1120
G +AT C V P +TW++N + P+ M N L +R D GT +
Sbjct: 1374 GDDATFRCEV-SPPDADVTWLRNGAVVTPGPQVEMAQNGSSRILTLRGCQLGDAGTVTLR 1432
Query: 1121 AVNDLGTVEIECKLEVK 1137
A G+ +L V+
Sbjct: 1433 A----GSTATSARLHVR 1445
Score = 32.3 bits (72), Expect = 2.6
Identities = 21/72 (29%), Positives = 30/72 (41%), Gaps = 4/72 (5%)
Query: 274 VELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYV----TAGDE 329
V L +P V W K GQ++ S + F G + L + TD Y AG+
Sbjct: 34 VVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLLLTAALPTDAGVYVCRARNAAGEA 93
Query: 330 KCSTELFVREPP 341
+ + V EPP
Sbjct: 94 YAAAAVTVLEPP 105
Score = 32.3 bits (72), Expect = 2.6
Identities = 17/55 (30%), Positives = 23/55 (41%)
Query: 283 VKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFV 337
V W + G E+ P KY G L I++ + D Y AG + T L V
Sbjct: 1839 VCWLREGAELCPGDKYEMRSHGPTHSLVIHDVRPEDQGTYCCQAGQDSTHTRLLV 1893
Score = 31.2 bits (69), Expect = 5.9
Identities = 25/100 (25%), Positives = 38/100 (38%), Gaps = 9/100 (9%)
Query: 1046 APMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQ------ 1099
AP+F + + + G L C G P+P + W K+ +A+ + F+ Q
Sbjct: 127 APVFLTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAED 186
Query: 1100 ---GVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
L I D G Y C A N G + L+V
Sbjct: 187 GPGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQV 226
>gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42
precursor [Homo sapiens]
Length = 2012
Score = 111 bits (278), Expect = 3e-24
Identities = 211/940 (22%), Positives = 348/940 (37%), Gaps = 172/940 (18%)
Query: 279 PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMT-DDSEYYVTAGDEKC------ 331
P +KWYKN S F H+ ++ F NN + D + V G+ C
Sbjct: 531 PYYSIKWYKN------SNLLPFNHR---QVAFENNGTLKLSDVQKEVDEGEYTCNVLVQP 581
Query: 332 ------STELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDA--NVKWFKNGEEIIP 383
S + V+ PP + + E G+RV + C V D + W K+G I P
Sbjct: 582 QLSTSQSVHVTVKVPPFI--QPFEFPRFSIGQRVFIPCVVVSGDLPITITWQKDGRPI-P 638
Query: 384 GPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGG------------QSSAKLSVDLK 431
G + ++ I+ + + S+M G + ++L V +
Sbjct: 639 GSLG---VTIDN------IDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVP 689
Query: 432 PLKILTPLTDQTVNLGKEICLKCEIS----ENIPGKWTKNG-----LPVQESDRLKVVHK 482
P ++ P DQ GK + L C I K++K P+ + R++V+
Sbjct: 690 PKFVVQP-RDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSN 748
Query: 483 GRIHKLVIANALTEDEGDY-------VFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTV 535
G L+I + + ED G Y V A + ++ L K+ P +I NT
Sbjct: 749 G---SLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTVKI-----PAMITS---YPNTT 797
Query: 536 TVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGR--IRTESYPDS--STLVIDIAER 591
G K + GE P W + D+ I R + T+ + STL I R
Sbjct: 798 LATQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLVSTKEVGEEVISTLQILPTVR 857
Query: 592 DDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPI 651
+DSG + + N GE I++ V + PDPP + +V + W +DG SPI
Sbjct: 858 EDSGFFSCHAINSYGEDRGIIQLTVQEPPDPPEI-EIKDVKARTITLRW-TMGFDGNSPI 915
Query: 652 LGYFIERKKKQSS-----RWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPS 706
GY IE K K S R ++ L T + + Y +R++A N IG S+PS
Sbjct: 916 TGYDIECKNKSDSWDSAQRTKDVSPQLNSATIID---IHPSSTYSIRMYAKNRIGKSEPS 972
Query: 707 MP-SRPFVPLAVTSPPTLLTVDSVTDTTVTMRWR-PPDHIGAAGLDGYVLEYCFEGSTSA 764
+ A PP + ++ ++ ++ + W+ P H+ + GY + Y
Sbjct: 973 NELTITADEAAPDGPPQEVHLEPISSQSIRVTWKAPKKHLQNGIIRGYQIGY-------- 1024
Query: 765 KQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYY 824
++ G ++ I++ D +T+ L + + V+A N AG
Sbjct: 1025 REYSTGGNFQFN------IISVDTSGDSEVYTLDNLNKFTQYGLVVQACNRAGTGPS--- 1075
Query: 825 SQPILVKEIIEPPK---------IRIPRHLKQTYIRRVGEAVNLVIP----------FQG 865
SQ I+ + + P P + ++ EA+N ++ G
Sbjct: 1076 SQEIITTTLEDVPSYPPENVQAIATSPESISISWSTLSKEALNGILQGFRVIYWANLMDG 1135
Query: 866 K--PRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETAS 923
+ +T + E+D + N + F R + S + + K D
Sbjct: 1136 ELGEIKNITTTQPSLELDGLE-KYTNYSIQVLAFTRAGDGVRSEQIFTRTKEDV------ 1188
Query: 924 IDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIE 983
PGPP VK V ++W PP N I YT+ S + TVI
Sbjct: 1189 --------PGPPAGVKAAAASASMVFVSWLPPL-KLNGIIRKYTV----FCSHPYPTVIS 1235
Query: 984 HYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDF 1043
+ + + FS + LS + + + G+ + +
Sbjct: 1236 EFEASPDS--------------FSYRIPNLSRNRQYSVWVVAVTSAGRGNSSEIITVEPL 1281
Query: 1044 SEAPMFTQPLVNTYAIAGY-NATLNCSVRGNPKPKITWMKNK----VAIVDDPRYRMFSN 1098
++AP T + L C G+P P + WMK+ + D R +FSN
Sbjct: 1282 AKAPARILTFSGTVTTPWMKDIVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSN 1341
Query: 1099 QGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1138
+ IR D G Y C A N+ G+ EI L+V+V
Sbjct: 1342 G---SFIIRTVKAEDSGYYSCIANNNWGSDEIILNLQVQV 1378
Score = 64.3 bits (155), Expect = 6e-10
Identities = 91/411 (22%), Positives = 168/411 (40%), Gaps = 53/411 (12%)
Query: 276 LADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTA----GDEKC 331
L P+ + +W K+ + S ++ G L I N + +D Y G K
Sbjct: 249 LGHPEPDYRWLKDNMPLELSGRFQKTVTG----LLIENIRPSDSGSYVCEVSNRYGTAKV 304
Query: 332 STELFVREPPIMVTKQLEDTTAYCGERVELECEVS-EDDANVKWFKNGEEIIPGPKSRYR 390
L+V++P + T + G +V L C V+ +D + W++NGE + PG
Sbjct: 305 IGRLYVKQP-LKATISPRKVKSSVGSQVSLSCSVTGTEDQELSWYRNGEILNPGK----N 359
Query: 391 IRVEGKKH-ILIIEGATKADAAEYSVMTTGGQSSAKLSVDL----KPLKILTPLTDQTVN 445
+R+ G H LI++ K+D Y + SA+ V + KI++ +++ V+
Sbjct: 360 VRITGINHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLEDGTPKIISAFSEKVVS 419
Query: 446 LGKEICLKCEISEN-IPG-KWTKNGLPVQE--SDRLK--VVHKGR-IHKLVIANALTEDE 498
+ + L C + +P WT + P+ + S R+ + +G + L I+++ D
Sbjct: 420 PAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDG 479
Query: 499 GDY-VFAPDAYNVTL-PAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPK 556
G Y A ++ V L A+++V P I +T IAG + + G P
Sbjct: 480 GVYRCTANNSAGVVLYQARINVRGPASI-----RPMKNITAIAGRDTYIHCRVIGYPYYS 534
Query: 557 AMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINL-----KNEAGEAHAS 611
W + + ++ E+ + + + D+ + D G Y N+ + + H +
Sbjct: 535 IKWYKNSNLLPFNHRQVAFEN--NGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQSVHVT 592
Query: 612 IKV----KVVDFPDPPVA-----PTVTEVGDDWCIMNWEPPAYDGGSPILG 653
+KV + +FP + P V GD + W+ G PI G
Sbjct: 593 VKVPPFIQPFEFPRFSIGQRVFIPCVVVSGDLPITITWQ----KDGRPIPG 639
Score = 49.7 bits (117), Expect = 2e-05
Identities = 86/371 (23%), Positives = 139/371 (37%), Gaps = 72/371 (19%)
Query: 778 PAEDWIVANKDLIDKTKF--TITGL------PTDAKIFVRVKAVNAAGASEP---KYYSQ 826
P W+ N L +F T+TGL P+D+ +V + N G ++ Y Q
Sbjct: 254 PDYRWLKDNMPLELSGRFQKTVTGLLIENIRPSDSGSYV-CEVSNRYGTAKVIGRLYVKQ 312
Query: 827 PILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ-I 885
P+ K I P K++ VG V+L G EL+W ++G ++ + +
Sbjct: 313 PL--KATISPRKVK----------SSVGSQVSLSCSVTGTEDQELSWYRNGEILNPGKNV 360
Query: 886 NIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWG 945
I + +I +S G Y V+ DK +A +Q++ G P+I+ +
Sbjct: 361 RITGINHENLIMDHMV-KSDGGAYQCFVRKDKL--SAQDYVQVVLEDGTPKIIS---AFS 414
Query: 946 ENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHY-----HRTSATITELVIGNE 1000
E V P N ++ ++ W + HR S IT GN
Sbjct: 415 EKVVSPAEPVSLMCN-------VKGTPLPTITWTLDDDPILKGGSHRISQMITSE--GNV 465
Query: 1001 YYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNP--------VYEDFDFSEAPMFTQP 1052
+ S + RDG +Y+ +Y+ P +P
Sbjct: 466 VSYLNISSSQ----------------VRDGGVYRCTANNSAGVVLYQARINVRGPASIRP 509
Query: 1053 LVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTL-EIRKPSP 1111
+ N AIAG + ++C V G P I W KN + + R F N G L +++K
Sbjct: 510 MKNITAIAGRDTYIHCRVIGYPYYSIKWYKNSNLLPFNHRQVAFENNGTLKLSDVQK--E 567
Query: 1112 YDGGTYCCKAV 1122
D G Y C +
Sbjct: 568 VDEGEYTCNVL 578
Score = 48.9 bits (115), Expect = 3e-05
Identities = 67/291 (23%), Positives = 116/291 (39%), Gaps = 34/291 (11%)
Query: 854 GEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQV 913
G+ V L G P P+ W KD ++ ++ R +T T + I S SG Y +V
Sbjct: 239 GQRVELPCKALGHPEPDYRWLKDNMPLE---LSGRFQKTVTGLLIENIRPSDSGSYVCEV 295
Query: 914 KVDKFVETASIDIQIIDRPGPPQIV--KIEDVWGENVALTWTPPKDDGNAAITGYTIQKA 971
+++ I + +P I K++ G V+L+ ++TG
Sbjct: 296 S-NRYGTAKVIGRLYVKQPLKATISPRKVKSSVGSQVSLS---------CSVTG-----T 340
Query: 972 DKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGK 1031
+ + + W+ E + + I +E G + + K+ + A+D
Sbjct: 341 EDQELSWYRNGEILN-PGKNVRITGINHENLIMDHMVKSDGGAYQCFVRKDK-LSAQD-- 396
Query: 1032 IYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDP 1091
Y V ED F++ +V+ +L C+V+G P P ITW + I+
Sbjct: 397 -YVQVVLEDGTPKIISAFSEKVVSP----AEPVSLMCNVKGTPLPTITWTLDDDPILKGG 451
Query: 1092 RYR---MFSNQG--VCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1137
+R M +++G V L I DGG Y C A N G V + ++ V+
Sbjct: 452 SHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVR 502
Score = 48.9 bits (115), Expect = 3e-05
Identities = 73/348 (20%), Positives = 129/348 (37%), Gaps = 45/348 (12%)
Query: 677 TTFEPKKMIEGVA----YEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDT 732
TT +P ++G+ Y +++ A G S V PP + + + +
Sbjct: 1144 TTTQPSLELDGLEKYTNYSIQVLAFTRAGDGVRSEQIFTRTKEDVPGPPAGVKAAAASAS 1203
Query: 733 TVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDK 792
V + W PP L+G + +Y S EA+ D
Sbjct: 1204 MVFVSWLPP-----LKLNGIIRKYTVFCSHPYPTVISEFEASPD---------------S 1243
Query: 793 TKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRR 852
+ I L + + V V AV +AG S+ I V+ + + P R L +
Sbjct: 1244 FSYRIPNLSRNRQYSVWVVAVTSAGRGNS---SEIITVEPLAKAPA----RILTFSGTVT 1296
Query: 853 VGEAVNLVIPFQ--GKPRPELTWKKDG------AEIDKNQINIRNSETDTIIFIRKAERS 904
++V+P + G P P + W KD ID + N IR +
Sbjct: 1297 TPWMKDIVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGS----FIIRTVKAE 1352
Query: 905 HSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAIT 964
SG Y + + +++Q+ P P++ + ++ L+W P D+G ++I
Sbjct: 1353 DSGYYSCIANNNWGSDEIILNLQVQVPPDQPRLT-VSKTTSSSITLSWLPG-DNGGSSIR 1410
Query: 965 GYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCG 1012
GY +Q ++ S +W + S + L G Y F + ++N G
Sbjct: 1411 GYILQYSEDNSEQWGSFPISPSERSYRLENLKCGTWYKFTLTAQNGVG 1458
Score = 48.1 bits (113), Expect = 5e-05
Identities = 43/176 (24%), Positives = 72/176 (40%), Gaps = 9/176 (5%)
Query: 529 LDADNTVTVIAGNKLRLEIPISGEPPPKAMW---SRGDKAIMEGSGRIRTESYPDSSTLV 585
L TVT + L G+P P W S G +++ GR S + + +
Sbjct: 1289 LTFSGTVTTPWMKDIVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGR---RSIFSNGSFI 1345
Query: 586 IDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAY 645
I + +DSG Y N G + ++V PD P TV++ ++W P
Sbjct: 1346 IRTVKAEDSGYYSCIANNNWGSDEIILNLQVQVPPDQPRL-TVSKTTSSSITLSWLP-GD 1403
Query: 646 DGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIG 701
+GGS I GY ++ + S +W E ++ + + G Y+ + A N +G
Sbjct: 1404 NGGSSIRGYILQYSEDNSEQWGSFPIS-PSERSYRLENLKCGTWYKFTLTAQNGVG 1458
Score = 46.6 bits (109), Expect = 1e-04
Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 4/94 (4%)
Query: 1044 SEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCT 1103
+ AP + A+AG L C G+P+P W+K+ + + R++ + V
Sbjct: 222 NSAPSILDGFDHRKAMAGQRVELPCKALGHPEPDYRWLKDNMPLELSGRFQ----KTVTG 277
Query: 1104 LEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1137
L I P D G+Y C+ N GT ++ +L VK
Sbjct: 278 LLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYVK 311
Score = 38.9 bits (89), Expect = 0.028
Identities = 32/90 (35%), Positives = 40/90 (44%), Gaps = 11/90 (12%)
Query: 1059 IAGYNATLNCSVRGNPKPKITWMKNKVA-------IVDDPRYRMFSNQGVCTLEIRKPSP 1111
I G LNCS G P P I W +K A I + R ++ SN +L I+
Sbjct: 702 IYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNG---SLLIKHVVE 758
Query: 1112 YDGGTYCCKAVNDLGT-VEIECKLEVKVIA 1140
D G Y CK ND+G V L VK+ A
Sbjct: 759 EDSGYYLCKVSNDVGADVSKSMYLTVKIPA 788
Score = 35.0 bits (79), Expect = 0.41
Identities = 40/180 (22%), Positives = 66/180 (36%), Gaps = 21/180 (11%)
Query: 441 DQTVNLGKEICLKCEISENIPG-----KWTKNGLPVQESDRLKVVHKGRIHKLVIANALT 495
DQ G KC I ++ W K+ + + R + G ++ + N
Sbjct: 132 DQKTMRGNVAVFKCIIPSSVEAYITVVSWEKDTVSLVSGSRFLITSTGALYIKDVQN--- 188
Query: 496 EDEGDYVFA-------PDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIP 548
++G Y + + A++ V DP LD + +AG ++ L
Sbjct: 189 -EDGLYNYRCITRHRYTGETRQSNSARLFVSDPANSAPSILDGFDHRKAMAGQRVELPCK 247
Query: 549 ISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEA 608
G P P W + D +E SGR + + L+I+ DSG Y + N G A
Sbjct: 248 ALGHPEPDYRWLK-DNMPLELSGRFQ----KTVTGLLIENIRPSDSGSYVCEVSNRYGTA 302
Score = 33.9 bits (76), Expect = 0.91
Identities = 28/108 (25%), Positives = 44/108 (40%), Gaps = 5/108 (4%)
Query: 260 PAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDD 319
P + + + + VV D + + W K+G+ I S ++ L I+N + +
Sbjct: 605 PRFSIGQRVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHN 664
Query: 320 SEYYVTAGDEKCSTE----LFVREPPIMVTKQLEDTTAYCGERVELEC 363
Y A +E + E L VR PP V Q D G+ V L C
Sbjct: 665 GNYTCIARNEAAAVEHQSQLIVRVPPKFVV-QPRDQDGIYGKAVILNC 711
>gi|21359935 Down syndrome cell adhesion molecule like 1 [Homo
sapiens]
Length = 2113
Score = 111 bits (277), Expect = 4e-24
Identities = 212/917 (23%), Positives = 350/917 (38%), Gaps = 123/917 (13%)
Query: 279 PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDE-----KCST 333
P +KWYK+ + + + + G ++ + D+ EY + + S
Sbjct: 592 PYYSIKWYKDALLLPDNHRQVVFENGTLKLTDVQKGM--DEGEYLCSVLIQPQLSISQSV 649
Query: 334 ELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVK--WFKNGEEIIPGPKSRYRI 391
+ V+ PP++ + E A G+ + + C VS D ++ W K+G+ II G +
Sbjct: 650 HVAVKVPPLI--QPFEFPPASIGQLLYIPCVVSSGDMPIRITWRKDGQVIISGSG----V 703
Query: 392 RVEGKKHI--LIIEGATKADAAEYSVMTTGGQSSA----KLSVDLKPLKILTPLTDQTVN 445
+E K+ + L I + Y+ + + ++ +L V + P ++ P +Q
Sbjct: 704 TIESKEFMSSLQISSVSLKHNGNYTCIASNAAATVSRERQLIVRVPPRFVVQP-NNQDGI 762
Query: 446 LGKEICLKCEISENIPGK--WT--------KNGLPVQESDRLKVVHKGRIHKLVIANALT 495
GK L C + P K W + PV + R++++ L+I + L
Sbjct: 763 YGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHPVPLTGRIQILPNS---SLLIRHVLE 819
Query: 496 EDEGDYVF-APDAYNVTLPAKVHV-IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEP 553
ED G Y+ A + + + + + P +I NT I G+ L GE
Sbjct: 820 EDIGYYLCQASNGVGTDISKSMFLTVKIPAMITSH---PNTTIAIKGHAKELNCTARGER 876
Query: 554 PPKAMWSRGDKAIMEGSGR---IRTESYPDS--STLVIDIAERDDSGVYHINLKNEAGEA 608
P W +GD I I T+ D STL + A+R DS + + N GE
Sbjct: 877 PIIIRWEKGDTVIDPDRVMRYAIATKDNGDEVVSTLKLKPADRGDSVFFSCHAINSYGED 936
Query: 609 HASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMR 668
I++ V + PDPP + EV + W +DG S I G+ IE K K S W
Sbjct: 937 RGLIQLTVQEPPDPPEL-EIREVKARSMNLRW-TQRFDGNSIITGFDIEYKNKSDS-WDF 993
Query: 669 LNFDLCKETTFEPKKMIE---GVAYEVRIFAVNAIGISKPSMP-SRPFVPLAVTSPPTLL 724
T +++ Y +R+++ N IG S+PS + A PP +
Sbjct: 994 KQSTRNISPTINQANIVDLHPASVYSIRMYSFNKIGRSEPSKELTISTEEAAPDGPPMDV 1053
Query: 725 TVDSVTDTTVTMRWR-PPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWI 783
T+ VT ++ + W+ P + + GY + Y +++ Y I
Sbjct: 1054 TLQPVTSQSIQVTWKAPKKELQNGVIRGYQIGY--------RENSPGSNGQYS------I 1099
Query: 784 VANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPR 843
V K D +T+ L A+ V V+A N AG ++++ P P
Sbjct: 1100 VEMKATGDSEVYTLDNLKKFAQYGVVVQAFNRAGTGPSSSEINATTLEDVPSQP----PE 1155
Query: 844 HLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAE-------IDKNQINIRN-SETDTI 895
+++ I + VI + PR L G +D ++N + T
Sbjct: 1156 NVRALSI----TSDVAVISWSEPPRSTLNGVLKGYRVIFWSLYVDGEWGEMQNITTTRER 1211
Query: 896 IFIRKAERSHSGKYDLQV----KVDKFVETASIDIQI-IDRPGPPQIVKIEDVWGENVAL 950
+ +R E+ + Y +QV + V ++ + IQ D PGPP +K +V +
Sbjct: 1212 VELRGMEKFTN--YSVQVLAYTQAGDGVRSSVLYIQTKEDVPGPPAGIKAVPSSASSVVV 1269
Query: 951 TWTPPKDDGNAAITGYTIQKADKKS-----MEWFTVIEH-YHRTSATITELVIGNEYYFR 1004
+W PP N I YTI + S E+ T E ++R I L G +Y
Sbjct: 1270 SWLPPTKP-NGVIRKYTIFCSSPGSGQPAPSEYETSPEQLFYR----IAHLNRGQQYLLW 1324
Query: 1005 VFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNA 1064
V + G + E I GK + S T P + +
Sbjct: 1325 VAAVTSAGRGN----SSEKVTIEPAGKAPAKII------SFGGTVTTPWMK-------DV 1367
Query: 1065 TLNCSVRGNPKPKITWMK---NKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKA 1121
L C+ G+P P + W K + V +R+ G TL +R D G Y C A
Sbjct: 1368 RLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNG--TLLLRAVKAEDSGYYTCTA 1425
Query: 1122 VNDLGTVEIECKLEVKV 1138
N G I L V+V
Sbjct: 1426 TNTGGFDTIIVNLLVQV 1442
Score = 65.1 bits (157), Expect = 4e-10
Identities = 141/752 (18%), Positives = 268/752 (35%), Gaps = 102/752 (13%)
Query: 316 MTDDSEYYVTAGDEKCSTEL-----FVREPPIMVTKQLEDTTAYCGERVELECEV-SEDD 369
+ +D YY+ T++ + P M+T T A G EL C E
Sbjct: 818 LEEDIGYYLCQASNGVGTDISKSMFLTVKIPAMITSHPNTTIAIKGHAKELNCTARGERP 877
Query: 370 ANVKWFKNGEEIIPGPKSRYRIRVEGKKHILI----IEGATKADAAEYS--VMTTGGQSS 423
++W K I P RY I + ++ ++ A + D+ +S + + G+
Sbjct: 878 IIIRWEKGDTVIDPDRVMRYAIATKDNGDEVVSTLKLKPADRGDSVFFSCHAINSYGEDR 937
Query: 424 AKLSVDLK-----PLKILTPLTDQTVNL-------GKEICLKCEIS-ENIPGKW-----T 465
+ + ++ P + + +++NL G I +I +N W T
Sbjct: 938 GLIQLTVQEPPDPPELEIREVKARSMNLRWTQRFDGNSIITGFDIEYKNKSDSWDFKQST 997
Query: 466 KNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKII 525
+N P + +H ++ + +++ + + P+K I +
Sbjct: 998 RNISPTINQANIVDLHPASVYSI------------RMYSFNKIGRSEPSKELTISTEEAA 1045
Query: 526 LDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTL- 584
DG D T+ + ++ ++ + P K + ++ G E+ P S+
Sbjct: 1046 PDGPPMDVTLQPVTSQSIQ----VTWKAPKKEL----QNGVIRGYQIGYRENSPGSNGQY 1097
Query: 585 -VIDIAERDDSGVYHI-NLK------------NEAGEAHASIKVKVVDFPDPPVAPT--- 627
++++ DS VY + NLK N AG +S ++ D P P
Sbjct: 1098 SIVEMKATGDSEVYTLDNLKKFAQYGVVVQAFNRAGTGPSSSEINATTLEDVPSQPPENV 1157
Query: 628 -VTEVGDDWCIMNW-EPPAYDGGSPILGY-FIERKKKQSSRWMRLNFDLCKETTFEPKKM 684
+ D +++W EPP + GY I W + E + M
Sbjct: 1158 RALSITSDVAVISWSEPPRSTLNGVLKGYRVIFWSLYVDGEWGEMQNITTTRERVELRGM 1217
Query: 685 IEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHI 744
+ Y V++ A G S V PP + + ++V + W PP
Sbjct: 1218 EKFTNYSVQVLAYTQAGDGVRSSVLYIQTKEDVPGPPAGIKAVPSSASSVVVSWLPPTKP 1277
Query: 745 GAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDA 804
+G + +Y S+ S + + Y+ E + I L
Sbjct: 1278 -----NGVIRKYTI--FCSSPGSGQPAPSEYETSPEQLF-----------YRIAHLNRGQ 1319
Query: 805 KIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPK--IRIPRHLKQTYIRRVGEAVNLVIP 862
+ + V AV +AG S+ + ++ + P I + +++ V N V
Sbjct: 1320 QYLLWVAAVTSAGRGNS---SEKVTIEPAGKAPAKIISFGGTVTTPWMKDVRLPCNSV-- 1374
Query: 863 FQGKPRPELTWKKDGAE--IDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVE 920
G P P + W KD + I + R T+ + +R + SG Y +
Sbjct: 1375 --GDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCTATNTGGFD 1432
Query: 921 TASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFT 980
T +++ + P P++ + ++ LTW P D+G ++I G+ +Q + S EW
Sbjct: 1433 TIIVNLLVQVPPDQPRLT-VSKTSASSITLTWIPG-DNGGSSIRGFVLQYSVDNSEEWKD 1490
Query: 981 VIEHYHRTSATITELVIGNEYYFRVFSENMCG 1012
V S + L G Y ++ ++N G
Sbjct: 1491 VFISSSERSFKLDSLKCGTWYKVKLAAKNSVG 1522
Score = 58.9 bits (141), Expect = 3e-08
Identities = 98/404 (24%), Positives = 161/404 (39%), Gaps = 84/404 (20%)
Query: 749 LDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFT--ITGLPT---- 802
LDG+ + + G T +G Y +PA W+ + L +++T ITGL
Sbjct: 289 LDGFHSQEVWAGHTVELPCTASG---YPIPAIRWLKDGRPLPADSRWTKRITGLTISDLR 345
Query: 803 --DAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRI-PRHLKQTYIRRVGEAVNL 859
D+ ++ + N G++E + IL+ +I+P + + P+ LK +G V L
Sbjct: 346 TEDSGTYI-CEVTNTFGSAE----ATGILM--VIDPLHVTLTPKKLKTG----IGSTVIL 394
Query: 860 VIPFQGKPRPELTWKKDGAEIDKNQ-INIRNSETDTIIFIRKAERSHSGKYDLQVKVDKF 918
G P + W ++ + ++ I+IR +T++ I A++SHSG Y Q +
Sbjct: 395 SCALTGSPEFTIRWYRNTELVLPDEAISIRGLSNETLL-ITSAQKSHSGAY--QCFATRK 451
Query: 919 VETASIDIQIIDRPGPPQIVKI--EDVW--GENVAL------------TWT----PPKDD 958
+TA I G P+IV E V GE +L TW P D
Sbjct: 452 AQTAQDFAIIALEDGTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRD 511
Query: 959 GNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDAT 1018
G+ YT+ T I H + T I + G Y R + N+ G +E
Sbjct: 512 GSHRTNQYTMSDG--------TTISHMNVTGPQIRD---GGVY--RCTARNLVGSAE--- 555
Query: 1019 MTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKI 1078
Y+ P + + N A+AG + +NC V G P I
Sbjct: 556 -------------------YQARINVRGPPSIRAMRNITAVAGRDTLINCRVIGYPYYSI 596
Query: 1079 TWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAV 1122
W K+ + + D+ R +F N + +++K D G Y C +
Sbjct: 597 KWYKDALLLPDNHRQVVFENGTLKLTDVQK--GMDEGEYLCSVL 638
Score = 57.0 bits (136), Expect = 1e-07
Identities = 88/383 (22%), Positives = 148/383 (38%), Gaps = 42/383 (10%)
Query: 283 VKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTE-------- 334
V W K+ I P ++ + G L+I++ Q D Y K S E
Sbjct: 219 VSWEKDTVSIIPEHRFFITYHGG---LYISDVQKEDALSTYRCITKHKYSGETRQSNGAR 275
Query: 335 LFVREPPIMVTKQLE---DTTAYCGERVELECEVSEDDAN-VKWFKNGEEIIPGPKSRYR 390
L V +P + L+ + G VEL C S ++W K+G + SR+
Sbjct: 276 LSVTDPAESIPTILDGFHSQEVWAGHTVELPCTASGYPIPAIRWLKDGRPL--PADSRWT 333
Query: 391 IRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLS---VDLKPLKI-LTPLTDQTVNL 446
R+ G L I D+ Y T SA+ + + + PL + LTP +T +
Sbjct: 334 KRITG----LTISDLRTEDSGTYICEVTNTFGSAEATGILMVIDPLHVTLTPKKLKT-GI 388
Query: 447 GKEICLKCEI--SENIPGKWTKNGLPVQESDRLKVVHKGRIHK-LVIANALTEDEGDY-V 502
G + L C + S +W +N V + + + +G ++ L+I +A G Y
Sbjct: 389 GSTVILSCALTGSPEFTIRWYRNTELVLPDEAISI--RGLSNETLLITSAQKSHSGAYQC 446
Query: 503 FAPDAYNVTLPAKVHVIDP--PKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWS 560
FA + ++ P+I+ + + V G + L G PPP W+
Sbjct: 447 FATRKAQTAQDFAIIALEDGTPRIV----SSFSEKVVNPGEQFSLMCAAKGAPPPTVTWA 502
Query: 561 RGDKAIM-EGSGRIRTESYPDSSTLV---IDIAERDDSGVYHINLKNEAGEAHASIKVKV 616
D+ I+ +GS R + D +T+ + + D GVY +N G A ++ V
Sbjct: 503 LDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINV 562
Query: 617 VDFPDPPVAPTVTEVGDDWCIMN 639
P +T V ++N
Sbjct: 563 RGPPSIRAMRNITAVAGRDTLIN 585
Score = 55.5 bits (132), Expect = 3e-07
Identities = 54/191 (28%), Positives = 83/191 (43%), Gaps = 17/191 (8%)
Query: 521 PPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRG--DKAI---MEGSGRIRT 575
P KII G TVT +RL G+P P W++ D AI M+G I T
Sbjct: 1349 PAKIISFG----GTVTTPWMKDVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHT 1404
Query: 576 ESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDW 635
+ TL++ + +DSG Y N G + + V PD P TV++
Sbjct: 1405 -----NGTLLLRAVKAEDSGYYTCTATNTGGFDTIIVNLLVQVPPDQP-RLTVSKTSASS 1458
Query: 636 CIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIF 695
+ W P +GGS I G+ ++ S W + F E +F+ + G Y+V++
Sbjct: 1459 ITLTW-IPGDNGGSSIRGFVLQYSVDNSEEWKDV-FISSSERSFKLDSLKCGTWYKVKLA 1516
Query: 696 AVNAIGISKPS 706
A N++G + S
Sbjct: 1517 AKNSVGSGRIS 1527
Score = 52.4 bits (124), Expect = 2e-06
Identities = 73/323 (22%), Positives = 125/323 (38%), Gaps = 56/323 (17%)
Query: 834 IEPPKIRIPRHLKQTYIRRV--GEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSE 891
+ P IP L + + V G V L G P P + W KDG + + R ++
Sbjct: 278 VTDPAESIPTILDGFHSQEVWAGHTVELPCTASGYPIPAIRWLKDGRPLPADS---RWTK 334
Query: 892 TDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALT 951
T + I SG Y +V + F + I ++ P + +T
Sbjct: 335 RITGLTISDLRTEDSGTYICEV-TNTFGSAEATGILMVIDP---------------LHVT 378
Query: 952 WTPPK---DDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSE 1008
TP K G+ I + + + ++ W+ TELV+ +E +
Sbjct: 379 LTPKKLKTGIGSTVILSCALTGSPEFTIRWY-----------RNTELVLPDE------AI 421
Query: 1009 NMCGLSEDATMTKESAVIARDGKIY-----KNPVYEDFDFSEAPMFTQPLVNTYA----I 1059
++ GLS + T+ SA + G K +DF T +V++++
Sbjct: 422 SIRGLSNE-TLLITSAQKSHSGAYQCFATRKAQTAQDFAIIALEDGTPRIVSSFSEKVVN 480
Query: 1060 AGYNATLNCSVRGNPKPKITWMKNKVAIVDD-----PRYRMFSNQGVCTLEIRKPSPYDG 1114
G +L C+ +G P P +TW + IV D +Y M + + + P DG
Sbjct: 481 PGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDG 540
Query: 1115 GTYCCKAVNDLGTVEIECKLEVK 1137
G Y C A N +G+ E + ++ V+
Sbjct: 541 GVYRCTARNLVGSAEYQARINVR 563
Score = 47.4 bits (111), Expect = 8e-05
Identities = 144/734 (19%), Positives = 269/734 (36%), Gaps = 95/734 (12%)
Query: 279 PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELF-- 336
P+ ++WY+N + + P + +L I + Q + Y A + + + F
Sbjct: 402 PEFTIRWYRNTELVLPDEAISIRGLSNETLL-ITSAQKSHSGAYQCFATRKAQTAQDFAI 460
Query: 337 --VREPPIMVTKQLEDTTAYCGERVELECEV-SEDDANVKWFKNGEEIIPGPKSR---YR 390
+ + + + GE+ L C V W + E I+ R Y
Sbjct: 461 IALEDGTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYT 520
Query: 391 IRVEGKKHILIIEGATKADAAEY--SVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGK 448
+ + + G D Y + G + + ++++ + + + T G+
Sbjct: 521 MSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGPPSIRAMRNITAVAGR 580
Query: 449 EICLKCEI--SENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY---VF 503
+ + C + KW K+ L + ++ R V G + + + DEG+Y V
Sbjct: 581 DTLINCRVIGYPYYSIKWYKDALLLPDNHRQVVFENGTLKLTDVQKGM--DEGEYLCSVL 638
Query: 504 APDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPI-SGEPPPKAMWSRG 562
+++ V V PP I G L + + SG+ P + W +
Sbjct: 639 IQPQLSISQSVHVAVKVPPLI-----QPFEFPPASIGQLLYIPCVVSSGDMPIRITWRKD 693
Query: 563 DKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDP 622
+ I+ GSG + ES S+L I +G Y N A ++ V P
Sbjct: 694 GQVIISGSG-VTIESKEFMSSLQISSVSLKHNGNYTCIASNAAATVSRERQLIVRVPPRF 752
Query: 623 PVAPT-----VTEVGDDWCIMNWEPP-------AYDGGSPILGYFIERKKKQSSRWMRLN 670
V P + G C ++ PP A G+P ++ +
Sbjct: 753 VVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNP---------QQYHPVPLTGR 803
Query: 671 FDLCKETTFEPKKMIEGVAYEVRIFAVNAIG--ISKPSMPSRPFVPLAVTSPPTLLTVDS 728
+ ++ + ++E A N +G ISK SM +P +TS P
Sbjct: 804 IQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISK-SMFLTVKIPAMITSHP------- 855
Query: 729 VTDTTVTMRWRPPD-HIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLP-AEDWIVAN 786
+TT+ ++ + + A G ++ + E G+ D + +A
Sbjct: 856 --NTTIAIKGHAKELNCTARGERPIIIRW------------EKGDTVIDPDRVMRYAIAT 901
Query: 787 KDLIDKTKFTITGLPTDA--KIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRI--- 841
KD D+ T+ P D +F A+N+ G E + Q + V+E +PP++ I
Sbjct: 902 KDNGDEVVSTLKLKPADRGDSVFFSCHAINSYG--EDRGLIQ-LTVQEPPDPPELEIREV 958
Query: 842 -PRHLKQTYIRRV-GEAVNLVIPFQGKPRPELTW--KKDGAEIDK--NQINIRNSETDTI 895
R + + +R G ++ + K + + +W K+ I NQ NI + ++
Sbjct: 959 KARSMNLRWTQRFDGNSIITGFDIEYKNKSD-SWDFKQSTRNISPTINQANIVDLHPASV 1017
Query: 896 IFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPP 955
IR + G+ + ++ E A+ D GPP V ++ V +++ +TW P
Sbjct: 1018 YSIRMYSFNKIGRSEPSKELTISTEEAAPD-------GPPMDVTLQPVTSQSIQVTWKAP 1070
Query: 956 KDD-GNAAITGYTI 968
K + N I GY I
Sbjct: 1071 KKELQNGVIRGYQI 1084
Score = 37.7 bits (86), Expect = 0.063
Identities = 80/341 (23%), Positives = 125/341 (36%), Gaps = 71/341 (20%)
Query: 809 RVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPR 868
R A N G++E Y I V+ PP IR R++ G + G P
Sbjct: 544 RCTARNLVGSAE---YQARINVRG---PPSIRAMRNITAV----AGRDTLINCRVIGYPY 593
Query: 869 PELTWKKDGAEIDKN--QINIRNSE---TDTIIFIRKAERSHSGKYDLQVKVDKFVETAS 923
+ W KD + N Q+ N TD + + E S Q+ + + V A
Sbjct: 594 YSIKWYKDALLLPDNHRQVVFENGTLKLTDVQKGMDEGEYLCSVLIQPQLSISQSVHVA- 652
Query: 924 IDIQIIDRPG--PP----QIVKIEDVWGEN---VALTWTPPKDDGNAAITGYTIQKADKK 974
+ + + +P PP Q++ I V + +TW + DG I+G + K+
Sbjct: 653 VKVPPLIQPFEFPPASIGQLLYIPCVVSSGDMPIRITW---RKDGQVIISGSGVTIESKE 709
Query: 975 SMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYK 1034
M +S I+ + + + + + N AT+++E +I R
Sbjct: 710 FM-----------SSLQISSVSLKHNGNYTCIASNAA-----ATVSRERQLIVR------ 747
Query: 1035 NPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVA-------- 1086
P F N I G LNCSV G P PK+ W K +
Sbjct: 748 ----------VPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHP 797
Query: 1087 IVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGT 1127
+ R ++ N +L IR D G Y C+A N +GT
Sbjct: 798 VPLTGRIQILPNS---SLLIRHVLEEDIGYYLCQASNGVGT 835
Score = 32.7 bits (73), Expect = 2.0
Identities = 52/245 (21%), Positives = 90/245 (36%), Gaps = 29/245 (11%)
Query: 273 VVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCS 332
VV D + + W K+GQ I + E K L I++ + + Y A + +
Sbjct: 678 VVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASNAAAT 737
Query: 333 T----ELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSR 388
+L VR PP V + Y G+ L C V +K+ + P+
Sbjct: 738 VSRERQLIVRVPPRFVVQPNNQDGIY-GKAGVLNCSVDGYPPPKVMWKHAKG-SGNPQQY 795
Query: 389 YRIRVEGKKHI-----LIIEGATKADAAEYSVMTTGG---QSSAKLSVDLKPLKILTPLT 440
+ + + G+ I L+I + D Y + G S + + +K ++T
Sbjct: 796 HPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIPAMITSHP 855
Query: 441 DQTVNL---GKEICLKCEISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTED 497
+ T+ + KE+ I +W K V+ R+ + IA T+D
Sbjct: 856 NTTIAIKGHAKELNCTARGERPIIIRWEKGD---------TVIDPDRVMRYAIA---TKD 903
Query: 498 EGDYV 502
GD V
Sbjct: 904 NGDEV 908
>gi|157785645 SPEG complex locus [Homo sapiens]
Length = 3267
Score = 110 bits (275), Expect = 8e-24
Identities = 162/662 (24%), Positives = 248/662 (37%), Gaps = 98/662 (14%)
Query: 278 DPKLEVKWYKNGQEIRPSTK-YIFEHKGCQRILFINNCQMTDDSEYYVTA----GDEKCS 332
+PK V W +N Q +RP + + E +G L I + D Y A G +C
Sbjct: 895 EPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLRILAAERGDAGFYTCKAVNEYGARQCE 954
Query: 333 TELFVREPP----IMVTKQLEDTTAYCGERVELECEVS-EDDANVKWFKNGEEIIPGPKS 387
L VR P + V L+D GE EC V+ D V W G + P
Sbjct: 955 ARLEVRAHPESRSLAVLAPLQDVDVGAGEMALFECLVAGPTDVEVDWLCRGRLLQPA-LL 1013
Query: 388 RYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPL-----TDQ 442
+ ++ +G+K L++ + D+ Y+ + + S L L PL D
Sbjct: 1014 KCKMHFDGRKCKLLLTSVHEDDSGVYTCKLSTAKDELTCSARLTVRPSLAPLFTRLLEDV 1073
Query: 443 TVNLGKEICLKCEISENIPG--KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGD 500
V G+ C+IS P WT G P++ES+ L++ G +H L IA+ +EDEG
Sbjct: 1074 EVLEGRAARFDCKISGTPPPVVTWTHFGCPMEESENLRLRQDGGLHSLHIAHVGSEDEG- 1132
Query: 501 YVFAPDAYN----VTLPAKVHVIDP--------------PKI-------------ILDGL 529
++A A N A+++V +P P I I D L
Sbjct: 1133 -LYAVSAVNTHGQAHCSAQLYVEEPRTAASGPSSKLEKMPSIPEEPEQGELERLSIPDFL 1191
Query: 530 DADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIA 589
+ V + LE ++G P P W I R R Y D LV
Sbjct: 1192 RPLQDLEVGLAKEAMLECQVTGLPYPTISWFHNGHRIQSSDDR-RMTQYRDVHRLVFPAV 1250
Query: 590 ERDDSGVYHINLKNEAGEAHASIKVKVVD-FPDPP-VAPTVTEVGDDWCIMNWEPP---- 643
+GVY + N+ G+A + V D P PP AP V V + W PP
Sbjct: 1251 GPQHAGVYKSVIANKLGKAACYAHLYVTDVVPGPPDGAPQVVAVTGRMVTLTWNPPRSLD 1310
Query: 644 -AYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGI 702
A D S L Y ++ + S +W L L +E + + +GV + R+ +
Sbjct: 1311 MAIDPDS--LTYTVQHQVLGSDQWTALVTGL-REPGWAATGLRKGVQHIFRVLSTTVKSS 1367
Query: 703 SKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGST 762
SKPS PS P L PTL ++ D PD + Y EG
Sbjct: 1368 SKPSPPSEPVQLL--EHGPTLEEAPAMLD--------KPD-----------IVYVVEGQP 1406
Query: 763 SAKQSDENGEAAYDLPAEDWIVANKDLID-KTKFTITGLPTDAKIFVRVKAVNAAG---- 817
++ N A + W L++ + P D + +R+ V+
Sbjct: 1407 ASVTVTFNHVEAQVV----WRSCRGALLEARAGVYELSQPDDDQYCLRICRVSRRDMGAL 1462
Query: 818 --ASEPKYYSQPILVK-EIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWK 874
+ ++ +Q V E+ E P+ + + GE + +GKP P++ W
Sbjct: 1463 TCTARNRHGTQTCSVTLELAEAPRF---ESIMEDVEVGAGETARFAVVVEGKPLPDIMWY 1519
Query: 875 KD 876
KD
Sbjct: 1520 KD 1521
Score = 73.2 bits (178), Expect = 1e-12
Identities = 92/409 (22%), Positives = 144/409 (35%), Gaps = 71/409 (17%)
Query: 277 ADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTA----GDEKCS 332
A+P +V W+K+G +R + + +G + L + + D Y TA G C+
Sbjct: 747 ANPPPQVSWHKDGSALRSEGRLLLRAEGERHTLLLREARAADAGSYMATATNELGQATCA 806
Query: 333 TELFVR--------------------------EP-------------------------- 340
L VR EP
Sbjct: 807 ASLTVRPGGSTSPFSSPITSDEEYLSPPEEFPEPGETWPRTPTMKPSPSQNRRSSDTGSK 866
Query: 341 -PIMVTKQLEDTTAYCGERVELECEVS-EDDANVKWFKNGEEIIPGPKSRYRIRVEGKKH 398
P L D + G+ V + V E V W +N + + P + R+ EG
Sbjct: 867 APPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQR-RFAEEAEGGLC 925
Query: 399 ILIIEGATKADAAEYSVMTTGG----QSSAKLSVDLKP----LKILTPLTDQTVNLGKEI 450
L I A + DA Y+ Q A+L V P L +L PL D V G+
Sbjct: 926 RLRILAAERGDAGFYTCKAVNEYGARQCEARLEVRAHPESRSLAVLAPLQDVDVGAGEMA 985
Query: 451 CLKCEIS--ENIPGKWTKNGLPVQESD-RLKVVHKGRIHKLVIANALTEDEGDYVFAPDA 507
+C ++ ++ W G +Q + + K+ GR KL++ + +D G Y
Sbjct: 986 LFECLVAGPTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDDSGVYTCKLST 1045
Query: 508 YNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIM 567
L + P + V V+ G R + ISG PPP W+ M
Sbjct: 1046 AKDELTCSARLTVRPSLAPLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFG-CPM 1104
Query: 568 EGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKV 616
E S +R +L I +D G+Y ++ N G+AH S ++ V
Sbjct: 1105 EESENLRLRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYV 1153
Score = 62.8 bits (151), Expect = 2e-09
Identities = 74/311 (23%), Positives = 123/311 (39%), Gaps = 55/311 (17%)
Query: 315 QMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDA-NVK 373
+ +DDS YV+AG+E +F E P L++ G V L+C ++ + V
Sbjct: 705 ESSDDS--YVSAGEEPLEAPVF--EIP------LQNVVVAPGADVLLKCIITANPPPQVS 754
Query: 374 WFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTG--GQSSAKLSVDLK 431
W K+G + + R +R EG++H L++ A ADA Y T GQ++ S+ ++
Sbjct: 755 WHKDGSAL--RSEGRLLLRAEGERHTLLLREARAADAGSYMATATNELGQATCAASLTVR 812
Query: 432 PLKILTPLTDQTVNLGKEICLKCEISENIPGK-WTKNGLPVQESDRLKVVHKGRIHKLVI 490
P +P + + + + E E PG+ W + P + +
Sbjct: 813 PGGSTSPFSSPITSDEEYLSPPEEFPE--PGETWPRT--PTMKPSPSQ------------ 856
Query: 491 ANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPIS 550
N + D G AP + V+L + +V G + + I +
Sbjct: 857 -NRRSSDTGSK--APPTFKVSLMDQ--------------------SVREGQDVIMSIRVQ 893
Query: 551 GEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHA 610
GEP P W R + + R E+ L I AER D+G Y NE G
Sbjct: 894 GEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLRILAAERGDAGFYTCKAVNEYGARQC 953
Query: 611 SIKVKVVDFPD 621
+++V P+
Sbjct: 954 EARLEVRAHPE 964
Score = 60.1 bits (144), Expect = 1e-08
Identities = 30/92 (32%), Positives = 49/92 (53%), Gaps = 1/92 (1%)
Query: 1047 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAI-VDDPRYRMFSNQGVCTLE 1105
P F L++ G + ++ V+G PKP ++W++N+ + D R+ + G+C L
Sbjct: 869 PTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLR 928
Query: 1106 IRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1137
I D G Y CKAVN+ G + E +LEV+
Sbjct: 929 ILAAERGDAGFYTCKAVNEYGARQCEARLEVR 960
Score = 55.5 bits (132), Expect = 3e-07
Identities = 29/93 (31%), Positives = 45/93 (48%)
Query: 1045 EAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTL 1104
EAP+F PL N G + L C + NP P+++W K+ A+ + R + + TL
Sbjct: 720 EAPVFEIPLQNVVVAPGADVLLKCIITANPPPQVSWHKDGSALRSEGRLLLRAEGERHTL 779
Query: 1105 EIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1137
+R+ D G+Y A N+LG L V+
Sbjct: 780 LLREARAADAGSYMATATNELGQATCAASLTVR 812
Score = 55.1 bits (131), Expect = 4e-07
Identities = 30/97 (30%), Positives = 43/97 (44%), Gaps = 2/97 (2%)
Query: 1042 DFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGV 1101
+ +EAP F + + AG A V G P P I W K++V + + +
Sbjct: 1480 ELAEAPRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEENE 1539
Query: 1102 CTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1138
C+L + DGG Y C A N G E+ CK E+ V
Sbjct: 1540 CSLVVLSTGAQDGGVYTCTAQNLAG--EVSCKAELAV 1574
Score = 48.5 bits (114), Expect = 4e-05
Identities = 27/94 (28%), Positives = 42/94 (44%)
Query: 1044 SEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCT 1103
S AP+FT+ L + + G A +C + G P P +TW + + R+ + G+ +
Sbjct: 1061 SLAPLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGCPMEESENLRLRQDGGLHS 1120
Query: 1104 LEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1137
L I D G Y AVN G +L V+
Sbjct: 1121 LHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVE 1154
Score = 48.5 bits (114), Expect = 4e-05
Identities = 82/357 (22%), Positives = 136/357 (38%), Gaps = 48/357 (13%)
Query: 804 AKIFVRVKAVNAAGASEPKYYSQPILVKEII--EPPKIRIPRHLKQTYIRRVGEAVNLVI 861
A+++V A+G S K P + +E E ++ IP L+ VG A ++
Sbjct: 1149 AQLYVEEPRTAASGPSS-KLEKMPSIPEEPEQGELERLSIPDFLRPLQDLEVGLAKEAML 1207
Query: 862 PFQ--GKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAER-SHSGKYDLQV--KVD 916
Q G P P ++W +G I + D + A H+G Y + K+
Sbjct: 1208 ECQVTGLPYPTISWFHNGHRIQSSDDRRMTQYRDVHRLVFPAVGPQHAGVYKSVIANKLG 1267
Query: 917 KFVETASIDIQIIDRPGPPQ-IVKIEDVWGENVALTWTPPKDDGNA----AITGYTIQKA 971
K A + + + PGPP ++ V G V LTW PP+ A ++T YT+Q
Sbjct: 1268 KAACYAHLYVTDVV-PGPPDGAPQVVAVTGRMVTLTWNPPRSLDMAIDPDSLT-YTVQHQ 1325
Query: 972 DKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGK 1031
S +W ++ T L G ++ FRV S + S+ + ++ ++
Sbjct: 1326 VLGSDQWTALVTGLREPGWAATGLRKGVQHIFRVLSTTVKSSSKPSPPSEPVQLLEH--- 1382
Query: 1032 IYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIV--- 1088
P E EAP Y + G A++ + + + ++ W + A++
Sbjct: 1383 ---GPTLE-----EAPAMLDKPDIVYVVEGQPASVTVTF-NHVEAQVVWRSCRGALLEAR 1433
Query: 1089 ---------DDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
DD +Y L I + S D G C A N GT LE+
Sbjct: 1434 AGVYELSQPDDDQY---------CLRICRVSRRDMGALTCTARNRHGTQTCSVTLEL 1481
Score = 46.6 bits (109), Expect = 1e-04
Identities = 29/91 (31%), Positives = 42/91 (46%), Gaps = 1/91 (1%)
Query: 1047 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFS-NQGVCTLE 1105
P+F L + + G ATL C P P I+WMK+K ++ +P + S G L
Sbjct: 2584 PVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDGRQLLS 2643
Query: 1106 IRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
I + G Y C A N LG++ C + V
Sbjct: 2644 IPRAGKRHAGLYECSATNVLGSITSSCTVAV 2674
Score = 43.5 bits (101), Expect = 0.001
Identities = 28/91 (30%), Positives = 39/91 (42%), Gaps = 7/91 (7%)
Query: 1046 APMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLE 1105
AP+F +PL N AG + L V G P+P + W + D + + C L
Sbjct: 42 APVFLRPLKNAAVCAGSDVRLRVVVSGTPQPSLRWFR------DGQLLPAPAPEPSC-LW 94
Query: 1106 IRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1136
+R+ D G Y C A N+ G E L V
Sbjct: 95 LRRCGAQDAGVYSCMAQNERGRASCEAVLTV 125
Score = 43.1 bits (100), Expect = 0.001
Identities = 36/161 (22%), Positives = 63/161 (39%), Gaps = 5/161 (3%)
Query: 854 GEAVNLVIPFQGKPRPELTWKKDGAEI--DKNQINIRNSETDTIIFIRKAERSHSGKYDL 911
GEA L+ P P ++W KD + + + I + + ++ I +A + H+G Y+
Sbjct: 2598 GEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDGRQLLSIPRAGKRHAGLYEC 2657
Query: 912 QVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKA 971
T+S + + PG ++ + + + W P D A T YT+++
Sbjct: 2658 SATNVLGSITSSCTVAVARVPGKLAPPEVPQTYQDTALVLWKP--GDSRAPCT-YTLERR 2714
Query: 972 DKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCG 1012
W V +T L +G FRV N G
Sbjct: 2715 VDGESVWHPVSSGIPDCYYNVTHLPVGVTVRFRVACANRAG 2755
Score = 42.4 bits (98), Expect = 0.003
Identities = 26/89 (29%), Positives = 39/89 (43%), Gaps = 8/89 (8%)
Query: 537 VIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGV 596
V AG+ +RL + +SG P P W R G++ P+ S L + D+GV
Sbjct: 54 VCAGSDVRLRVVVSGTPQPSLRWFR--------DGQLLPAPAPEPSCLWLRRCGAQDAGV 105
Query: 597 YHINLKNEAGEAHASIKVKVVDFPDPPVA 625
Y +NE G A + V++ D A
Sbjct: 106 YSCMAQNERGRASCEAVLTVLEVGDSETA 134
Score = 39.3 bits (90), Expect = 0.022
Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 4/100 (4%)
Query: 535 VTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDS 594
V V AG R + + G+P P MW + D+ ++ S + + +LV+ D
Sbjct: 1494 VEVGAGETARFAVVVEGKPLPDIMWYK-DEVLLTESSHVSFVYEENECSLVVLSTGAQDG 1552
Query: 595 GVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDD 634
GVY +N AGE ++ V A V VG+D
Sbjct: 1553 GVYTCTAQNLAGEVSCKAELAV---HSAQTAMEVEGVGED 1589
Score = 39.3 bits (90), Expect = 0.022
Identities = 44/193 (22%), Positives = 71/193 (36%), Gaps = 8/193 (4%)
Query: 553 PPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASI 612
P P W + K++ I L I A + +G+Y + N G +S
Sbjct: 2611 PAPHISWMKDKKSLRSEPSVIIVSCKDGRQLLSIPRAGKRHAGLYECSATNVLGSITSSC 2670
Query: 613 KVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFD 672
V V P P V + D ++ W+P D +P Y +ER+ S W ++
Sbjct: 2671 TVAVARVPGKLAPPEVPQTYQDTALVLWKPG--DSRAPCT-YTLERRVDGESVWHPVSSG 2727
Query: 673 LCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDT 732
+ + + + GV R+ N G P S V + T + + + +
Sbjct: 2728 I-PDCYYNVTHLPVGVTVRFRVACANRAG-QGPFSNSSEKVFVRGTQDSSAVPSAAHQEA 2785
Query: 733 TVT---MRWRPPD 742
VT R RPPD
Sbjct: 2786 PVTSRPARARPPD 2798
Score = 31.2 bits (69), Expect = 5.9
Identities = 20/80 (25%), Positives = 37/80 (46%), Gaps = 4/80 (5%)
Query: 831 KEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI-DKNQINIRN 889
+E +E P IP Q + G V L P P+++W KDG+ + + ++ +R
Sbjct: 716 EEPLEAPVFEIPL---QNVVVAPGADVLLKCIITANPPPQVSWHKDGSALRSEGRLLLRA 772
Query: 890 SETDTIIFIRKAERSHSGKY 909
+ +R+A + +G Y
Sbjct: 773 EGERHTLLLREARAADAGSY 792
>gi|19743806 roundabout 1 isoform b [Homo sapiens]
Length = 1612
Score = 105 bits (261), Expect = 3e-22
Identities = 126/476 (26%), Positives = 180/476 (37%), Gaps = 65/476 (13%)
Query: 279 PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGD------EKCS 332
P+ + W K+G + + I G I + D+ YV G E
Sbjct: 159 PEPTISWKKDGSPLDDKDERITIRGGKLMITYTRK----SDAGKYVCVGTNMVGERESEV 214
Query: 333 TELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDA-NVKWFKNGEEIIPGPKSRYRI 391
EL V E P V K+ + + E +CE D V+W K+ E+ PKSRY I
Sbjct: 215 AELTVLERPSFV-KRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGEL---PKSRYEI 270
Query: 392 RVEGKKHILIIEGATKADAAEYSV----MTTGGQSSAKLSVDLKPLKILTPLTDQTVNLG 447
R + H L I T D Y+ M ++SA L+V P ++ P DQ V LG
Sbjct: 271 RDD---HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPHFVVKP-RDQVVALG 326
Query: 448 KEICLKCEISENIPGK--WTKNGL--------PVQESDRLKVVHKGRIHKLVIANALTED 497
+ + +CE + N W + G P Q S R V G L I N D
Sbjct: 327 RTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTG---DLTITNVQRSD 383
Query: 498 EGDYVFAP--DAYNVTLPAKVHVID-----PPKIILDGLDADNTVTVIAGNKLRLEIPIS 550
G Y+ A ++ A + V D PP +I G TV L +
Sbjct: 384 VGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQG---PVNQTVAVDGTFVLSCVAT 440
Query: 551 GEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHA 610
G P P +W + + RI+ ++ L I A+ D+G Y +GEA
Sbjct: 441 GSPVPTILWRKDGVLVSTQDSRIKQL---ENGVLQIRYAKLGDTGRYTCIASTPSGEATW 497
Query: 611 SIKVKVVDF---------------PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYF 655
S ++V +F P P P VT+V + ++W+P G +P Y
Sbjct: 498 SAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATP-TSYI 556
Query: 656 IERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRP 711
IE S + + K T K + Y + A NA GIS PS S P
Sbjct: 557 IEAFSHASGSSWQTVAENVKTETSAIKGLKPNAIYLFLVRAANAYGISDPSQISDP 612
Score = 74.7 bits (182), Expect = 5e-13
Identities = 181/784 (23%), Positives = 287/784 (36%), Gaps = 125/784 (15%)
Query: 350 DTTAYCGERVELECEV--SEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATK 407
D GE +EC+ + + W K+G P RI + G K L+I K
Sbjct: 139 DVMVAVGEPAVMECQPPRGHPEPTISWKKDGS---PLDDKDERITIRGGK--LMITYTRK 193
Query: 408 ADAAEYSVMTT---GGQSS--AKLSVDLKPLKILTPLTDQTVNLGKEICLKCEI-SENIP 461
+DA +Y + T G + S A+L+V +P + P ++ V + KCE + +P
Sbjct: 194 SDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRP-SNLAVTVDDSAEFKCEARGDPVP 252
Query: 462 G-KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAY--NVTLPAKVHV 518
+W K+ + +S R ++ H L I D G Y + A + V
Sbjct: 253 TVRWRKDDGELPKS-RYEIRDD---HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV 308
Query: 519 IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESY 578
+PP ++ D V G + + +G P P W R EGS +
Sbjct: 309 QEPPHFVVKPRDQ----VVALGRTVTFQCEATGNPQPAIFWRR------EGSQNLLFSYQ 358
Query: 579 PDSST----------LVIDIAERDDSGVYHINLKNEAG----EAHASIKVKVVDFPDP-- 622
P S+ L I +R D G Y N AG +A+ + + D P P
Sbjct: 359 PPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVI 418
Query: 623 ---PVAPTVTEVGDDW--CIMNWEPPA---YDGGSPILGYFIERKKKQSSRWMRLNFDLC 674
PV TV G C+ P + ++ R K+ + +++ +
Sbjct: 419 RQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKL 478
Query: 675 KET------TFEPKKMIEGVAY-EVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVD 727
+T P AY EV+ F V P P RP P + S P+ V
Sbjct: 479 GDTGRYTCIASTPSGEATWSAYIEVQEFGV-------PVQPPRPTDPNLIPSAPSKPEVT 531
Query: 728 SVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANK 787
V+ TVT+ W+P + GA Y++E S S+ W +
Sbjct: 532 DVSRNTVTLSWQPNLNSGATP-TSYIIEAFSHASGSS-----------------WQTVAE 573
Query: 788 DLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQ 847
++ +T I GL +A V+A NA G S+P S P+ ++++ P + Q
Sbjct: 574 NVKTETS-AIKGLKPNAIYLFLVRAANAYGISDPSQISDPVKTQDVL-PTSQGVDHKQVQ 631
Query: 848 TYIRRVGEAV-NLVIP-FQGKPRPELTWKKD-------GAEIDKNQINIRNSETDTIIF- 897
R +G AV +L P E+ W D G +I + E+D ++F
Sbjct: 632 ---RELGNAVLHLHNPTVLSSSSIEVHWTVDQQSQYIQGYKILYRPSGANHGESDWLVFE 688
Query: 898 IRKAERSHSGKYDLQVKVDK-------FVETASIDIQI------IDRP-GPPQIVKI--E 941
+R ++ DL+ V+ F E D +I + P PPQ V +
Sbjct: 689 VRTPAKNSVVIPDLRKGVNYEIKARPFFNEFQGADSEIKFAKTLEEAPSAPPQGVTVSKN 748
Query: 942 DVWGENVALTWTPPKDD-GNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNE 1000
D G + ++W PP +D N + Y + ++ S I LV G
Sbjct: 749 DGNGTAILVSWQPPPEDTQNGMVQEYKVWCLGNETRYHINKTVDGSTFSVVIPFLVPGIR 808
Query: 1001 YYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIA 1060
Y V + G + + E I D + NPV + S A + + IA
Sbjct: 809 YSVEVAASTGAG----SGVKSEPQFIQLDA--HGNPVSPEDQVSLAQQISDVVKQPAFIA 862
Query: 1061 GYNA 1064
G A
Sbjct: 863 GIGA 866
Score = 65.1 bits (157), Expect = 4e-10
Identities = 143/636 (22%), Positives = 237/636 (37%), Gaps = 80/636 (12%)
Query: 422 SSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPG---KWTKNGLPVQ------ 472
S ++L + P +I+ +D V+ G+ L C+ +E P +W K G V+
Sbjct: 18 SGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCK-AEGRPTPTIEWYKGGERVETDKDDP 76
Query: 473 ESDRLKVVHKGRIHKLVIANALTE--DEGDYVFAPDAYNVTLPAKVHVIDPPKIIL--DG 528
S R+ ++ G + L I + DEG YV A N A H IL D
Sbjct: 77 RSHRM-LLPSGSLFFLRIVHGRKSRPDEGVYVCV--ARNYLGEAVSHNASLEVAILRDDF 133
Query: 529 LDADNTVTVIAGNKLRLEI-PISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVID 587
+ V V G +E P G P P W + + + RI L+I
Sbjct: 134 RQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRG----GKLMIT 189
Query: 588 IAERDDSGVYHINLKNEAGEAHASI-KVKVVDFPD-----PPVAPTVTEVGDDWCIMNWE 641
+ D+G Y N GE + + ++ V++ P +A TV + + C +
Sbjct: 190 YTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGD 249
Query: 642 PPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIG 701
P R +K + +++ + T + +K+ G A N +G
Sbjct: 250 PVP-----------TVRWRKDDGELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVG 298
Query: 702 ISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGS 761
++ S L V PP + D V + A G + + EGS
Sbjct: 299 KAEAS------ATLTVQEPPHFVV--KPRDQVVALGRTVTFQCEATGNPQPAIFWRREGS 350
Query: 762 TSAKQSDENGEAAYDLPAEDWIVANKDLIDKT-KFTITGLPTDAKIFVRVKAVNAAGASE 820
+N +Y P +++ + +T TIT + + + +N AG+
Sbjct: 351 -------QNLLFSYQPPQS----SSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSII 399
Query: 821 PKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI 880
K Y + V PP IR + QT V L G P P + W+KDG +
Sbjct: 400 TKAYLEVTDVIADRPPPVIR-QGPVNQTVA--VDGTFVLSCVATGSPVPTILWRKDGVLV 456
Query: 881 DKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIID--------RP 932
I+ E + ++ IR A+ +G+Y T S I++ + RP
Sbjct: 457 STQDSRIKQLE-NGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRP 515
Query: 933 GPPQIV-------KIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKS-MEWFTVIEH 984
P ++ ++ DV V L+W P + G A T Y I+ S W TV E+
Sbjct: 516 TDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSG-ATPTSYIIEAFSHASGSSWQTVAEN 574
Query: 985 YHRTSATITELVIGNEYYFRVFSENMCGLSEDATMT 1020
++ I L Y F V + N G+S+ + ++
Sbjct: 575 VKTETSAIKGLKPNAIYLFLVRAANAYGISDPSQIS 610
Score = 54.3 bits (129), Expect = 6e-07
Identities = 78/308 (25%), Positives = 122/308 (39%), Gaps = 69/308 (22%)
Query: 853 VGE-AVNLVIPFQGKPRPELTWKKDGAEID--KNQINIRNSETDTIIFIRKAERSHSGKY 909
VGE AV P +G P P ++WKKDG+ +D +I IR + + I +S +GKY
Sbjct: 144 VGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGK----LMITYTRKSDAGKY 199
Query: 910 DLQVKVDKFVETAS--IDIQIIDRPG----PPQI-VKIED-------VWGENV-ALTWTP 954
+ V + E S ++ +++RP P + V ++D G+ V + W
Sbjct: 200 -VCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWR- 257
Query: 955 PKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLS 1014
KDDG + Y I+ +H + I ++ G+ + +ENM G +
Sbjct: 258 -KDDGELPKSRYEIRD------------DH----TLKIRKVTAGDMGSYTCVAENMVGKA 300
Query: 1015 E-DATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGN 1073
E AT+T + E P F + G T C GN
Sbjct: 301 EASATLTVQ----------------------EPPHFVVKPRDQVVALGRTVTFQCEATGN 338
Query: 1074 PKPKITWMK----NKVAIVDDPR-YRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTV 1128
P+P I W + N + P+ FS L I D G Y C+ +N G++
Sbjct: 339 PQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSI 398
Query: 1129 EIECKLEV 1136
+ LEV
Sbjct: 399 ITKAYLEV 406
Score = 49.7 bits (117), Expect = 2e-05
Identities = 71/321 (22%), Positives = 122/321 (38%), Gaps = 58/321 (18%)
Query: 836 PPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSE---- 891
PP RI H + + GE L +G+P P + W K G ++ ++ + R+
Sbjct: 28 PP--RIVEHPSDLIVSK-GEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLP 84
Query: 892 TDTIIFIR----KAERSHSGKYDLQVKV---DKFVETASIDIQIID---RPGPPQIVKIE 941
+ ++ F+R + R G Y + + AS+++ I+ R P ++
Sbjct: 85 SGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAV 144
Query: 942 DVWGENVALTWTPPKDDGNAAIT----GYTIQKADKK-SMEWFTVIEHYHRTSATITELV 996
GE + PP+ I+ G + D++ ++ ++ Y R S +
Sbjct: 145 ---GEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVC 201
Query: 997 IGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNT 1056
+G NM G +ES V + E P F + N
Sbjct: 202 VGT---------NMVG-------ERESEVA-------------ELTVLERPSFVKRPSNL 232
Query: 1057 YAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGT 1116
+A C RG+P P + W K+ + RY + + TL+IRK + D G+
Sbjct: 233 AVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKS-RYEIRDDH---TLKIRKVTAGDMGS 288
Query: 1117 YCCKAVNDLGTVEIECKLEVK 1137
Y C A N +G E L V+
Sbjct: 289 YTCVAENMVGKAEASATLTVQ 309
Score = 48.9 bits (115), Expect = 3e-05
Identities = 84/349 (24%), Positives = 133/349 (38%), Gaps = 51/349 (14%)
Query: 802 TDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVI 861
+DA +V V N G E + +L + P ++ P +L T V ++
Sbjct: 194 SDAGKYVCV-GTNMVGERESEVAELTVLER----PSFVKRPSNLAVT----VDDSAEFKC 244
Query: 862 PFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVK--VDKFV 919
+G P P + W+KD E+ K++ IR+ T + IRK G Y + V K
Sbjct: 245 EARGDPVPTVRWRKDDGELPKSRYEIRDDHT---LKIRKVTAGDMGSYTCVAENMVGKAE 301
Query: 920 ETASIDIQIIDRPGPPQ-IVKIEDVWGENVALTWTPP---KDDGNAAITGYTIQKADKKS 975
+A++ +Q PP +VK D + VAL T + GN + ++ +
Sbjct: 302 ASATLTVQ-----EPPHFVVKPRD---QVVALGRTVTFQCEATGNPQPAIFWRREGSQNL 353
Query: 976 MEWFTVIEHYHRTSA------TITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARD 1029
+ + + R S TIT + + Y+ + N+ G + + VIA
Sbjct: 354 LFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIAD- 412
Query: 1030 GKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAI-V 1088
P+ Q VN L+C G+P P I W K+ V +
Sbjct: 413 --------------RPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVST 458
Query: 1089 DDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1137
D R + N GV L+IR D G Y C A G +EV+
Sbjct: 459 QDSRIKQLEN-GV--LQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQ 504
Score = 42.7 bits (99), Expect = 0.002
Identities = 34/88 (38%), Positives = 40/88 (45%), Gaps = 10/88 (11%)
Query: 1061 GYNATLNCSVRGNPKPKITWMKNKVAI---VDDPR-YRMFSNQG----VCTLEIRKPSPY 1112
G ATLNC G P P I W K + DDPR +RM G + + RK P
Sbjct: 43 GEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRP- 101
Query: 1113 DGGTYCCKAVNDLG-TVEIECKLEVKVI 1139
D G Y C A N LG V LEV ++
Sbjct: 102 DEGVYVCVARNYLGEAVSHNASLEVAIL 129
>gi|4506569 roundabout 1 isoform a [Homo sapiens]
Length = 1651
Score = 105 bits (261), Expect = 3e-22
Identities = 126/476 (26%), Positives = 180/476 (37%), Gaps = 65/476 (13%)
Query: 279 PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGD------EKCS 332
P+ + W K+G + + I G I + D+ YV G E
Sbjct: 198 PEPTISWKKDGSPLDDKDERITIRGGKLMITYTRK----SDAGKYVCVGTNMVGERESEV 253
Query: 333 TELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDA-NVKWFKNGEEIIPGPKSRYRI 391
EL V E P V K+ + + E +CE D V+W K+ E+ PKSRY I
Sbjct: 254 AELTVLERPSFV-KRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGEL---PKSRYEI 309
Query: 392 RVEGKKHILIIEGATKADAAEYSV----MTTGGQSSAKLSVDLKPLKILTPLTDQTVNLG 447
R + H L I T D Y+ M ++SA L+V P ++ P DQ V LG
Sbjct: 310 RDD---HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPHFVVKP-RDQVVALG 365
Query: 448 KEICLKCEISENIPGK--WTKNGL--------PVQESDRLKVVHKGRIHKLVIANALTED 497
+ + +CE + N W + G P Q S R V G L I N D
Sbjct: 366 RTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTG---DLTITNVQRSD 422
Query: 498 EGDYVFAP--DAYNVTLPAKVHVID-----PPKIILDGLDADNTVTVIAGNKLRLEIPIS 550
G Y+ A ++ A + V D PP +I G TV L +
Sbjct: 423 VGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQG---PVNQTVAVDGTFVLSCVAT 479
Query: 551 GEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHA 610
G P P +W + + RI+ ++ L I A+ D+G Y +GEA
Sbjct: 480 GSPVPTILWRKDGVLVSTQDSRIKQL---ENGVLQIRYAKLGDTGRYTCIASTPSGEATW 536
Query: 611 SIKVKVVDF---------------PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYF 655
S ++V +F P P P VT+V + ++W+P G +P Y
Sbjct: 537 SAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATP-TSYI 595
Query: 656 IERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRP 711
IE S + + K T K + Y + A NA GIS PS S P
Sbjct: 596 IEAFSHASGSSWQTVAENVKTETSAIKGLKPNAIYLFLVRAANAYGISDPSQISDP 651
Score = 74.7 bits (182), Expect = 5e-13
Identities = 181/784 (23%), Positives = 287/784 (36%), Gaps = 125/784 (15%)
Query: 350 DTTAYCGERVELECEV--SEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATK 407
D GE +EC+ + + W K+G P RI + G K L+I K
Sbjct: 178 DVMVAVGEPAVMECQPPRGHPEPTISWKKDGS---PLDDKDERITIRGGK--LMITYTRK 232
Query: 408 ADAAEYSVMTT---GGQSS--AKLSVDLKPLKILTPLTDQTVNLGKEICLKCEI-SENIP 461
+DA +Y + T G + S A+L+V +P + P ++ V + KCE + +P
Sbjct: 233 SDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRP-SNLAVTVDDSAEFKCEARGDPVP 291
Query: 462 G-KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAY--NVTLPAKVHV 518
+W K+ + +S R ++ H L I D G Y + A + V
Sbjct: 292 TVRWRKDDGELPKS-RYEIRDD---HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV 347
Query: 519 IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESY 578
+PP ++ D V G + + +G P P W R EGS +
Sbjct: 348 QEPPHFVVKPRDQ----VVALGRTVTFQCEATGNPQPAIFWRR------EGSQNLLFSYQ 397
Query: 579 PDSST----------LVIDIAERDDSGVYHINLKNEAG----EAHASIKVKVVDFPDP-- 622
P S+ L I +R D G Y N AG +A+ + + D P P
Sbjct: 398 PPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVI 457
Query: 623 ---PVAPTVTEVGDDW--CIMNWEPPA---YDGGSPILGYFIERKKKQSSRWMRLNFDLC 674
PV TV G C+ P + ++ R K+ + +++ +
Sbjct: 458 RQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKL 517
Query: 675 KET------TFEPKKMIEGVAY-EVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVD 727
+T P AY EV+ F V P P RP P + S P+ V
Sbjct: 518 GDTGRYTCIASTPSGEATWSAYIEVQEFGV-------PVQPPRPTDPNLIPSAPSKPEVT 570
Query: 728 SVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANK 787
V+ TVT+ W+P + GA Y++E S S+ W +
Sbjct: 571 DVSRNTVTLSWQPNLNSGATP-TSYIIEAFSHASGSS-----------------WQTVAE 612
Query: 788 DLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQ 847
++ +T I GL +A V+A NA G S+P S P+ ++++ P + Q
Sbjct: 613 NVKTETS-AIKGLKPNAIYLFLVRAANAYGISDPSQISDPVKTQDVL-PTSQGVDHKQVQ 670
Query: 848 TYIRRVGEAV-NLVIP-FQGKPRPELTWKKD-------GAEIDKNQINIRNSETDTIIF- 897
R +G AV +L P E+ W D G +I + E+D ++F
Sbjct: 671 ---RELGNAVLHLHNPTVLSSSSIEVHWTVDQQSQYIQGYKILYRPSGANHGESDWLVFE 727
Query: 898 IRKAERSHSGKYDLQVKVDK-------FVETASIDIQI------IDRP-GPPQIVKI--E 941
+R ++ DL+ V+ F E D +I + P PPQ V +
Sbjct: 728 VRTPAKNSVVIPDLRKGVNYEIKARPFFNEFQGADSEIKFAKTLEEAPSAPPQGVTVSKN 787
Query: 942 DVWGENVALTWTPPKDD-GNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNE 1000
D G + ++W PP +D N + Y + ++ S I LV G
Sbjct: 788 DGNGTAILVSWQPPPEDTQNGMVQEYKVWCLGNETRYHINKTVDGSTFSVVIPFLVPGIR 847
Query: 1001 YYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIA 1060
Y V + G + + E I D + NPV + S A + + IA
Sbjct: 848 YSVEVAASTGAG----SGVKSEPQFIQLDA--HGNPVSPEDQVSLAQQISDVVKQPAFIA 901
Query: 1061 GYNA 1064
G A
Sbjct: 902 GIGA 905
Score = 65.9 bits (159), Expect = 2e-10
Identities = 143/638 (22%), Positives = 238/638 (37%), Gaps = 80/638 (12%)
Query: 420 GQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPG---KWTKNGLPVQ---- 472
G + ++L + P +I+ +D V+ G+ L C+ +E P +W K G V+
Sbjct: 55 GYTGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCK-AEGRPTPTIEWYKGGERVETDKD 113
Query: 473 --ESDRLKVVHKGRIHKLVIANALTE--DEGDYVFAPDAYNVTLPAKVHVIDPPKIIL-- 526
S R+ ++ G + L I + DEG YV A N A H IL
Sbjct: 114 DPRSHRM-LLPSGSLFFLRIVHGRKSRPDEGVYVCV--ARNYLGEAVSHNASLEVAILRD 170
Query: 527 DGLDADNTVTVIAGNKLRLEI-PISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLV 585
D + V V G +E P G P P W + + + RI L+
Sbjct: 171 DFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRG----GKLM 226
Query: 586 IDIAERDDSGVYHINLKNEAGEAHASI-KVKVVDFPD-----PPVAPTVTEVGDDWCIMN 639
I + D+G Y N GE + + ++ V++ P +A TV + + C
Sbjct: 227 ITYTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEAR 286
Query: 640 WEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNA 699
+P R +K + +++ + T + +K+ G A N
Sbjct: 287 GDPVP-----------TVRWRKDDGELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENM 335
Query: 700 IGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFE 759
+G ++ S L V PP + D V + A G + + E
Sbjct: 336 VGKAEAS------ATLTVQEPPHFVV--KPRDQVVALGRTVTFQCEATGNPQPAIFWRRE 387
Query: 760 GSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKT-KFTITGLPTDAKIFVRVKAVNAAGA 818
GS +N +Y P +++ + +T TIT + + + +N AG+
Sbjct: 388 GS-------QNLLFSYQPPQS----SSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGS 436
Query: 819 SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGA 878
K Y + V PP IR + QT V L G P P + W+KDG
Sbjct: 437 IITKAYLEVTDVIADRPPPVIR-QGPVNQTVA--VDGTFVLSCVATGSPVPTILWRKDGV 493
Query: 879 EIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIID-------- 930
+ I+ E + ++ IR A+ +G+Y T S I++ +
Sbjct: 494 LVSTQDSRIKQLE-NGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPP 552
Query: 931 RPGPPQIV-------KIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKS-MEWFTVI 982
RP P ++ ++ DV V L+W P + G A T Y I+ S W TV
Sbjct: 553 RPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSG-ATPTSYIIEAFSHASGSSWQTVA 611
Query: 983 EHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMT 1020
E+ ++ I L Y F V + N G+S+ + ++
Sbjct: 612 ENVKTETSAIKGLKPNAIYLFLVRAANAYGISDPSQIS 649
Score = 54.3 bits (129), Expect = 6e-07
Identities = 78/308 (25%), Positives = 122/308 (39%), Gaps = 69/308 (22%)
Query: 853 VGE-AVNLVIPFQGKPRPELTWKKDGAEID--KNQINIRNSETDTIIFIRKAERSHSGKY 909
VGE AV P +G P P ++WKKDG+ +D +I IR + + I +S +GKY
Sbjct: 183 VGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGK----LMITYTRKSDAGKY 238
Query: 910 DLQVKVDKFVETAS--IDIQIIDRPG----PPQI-VKIED-------VWGENV-ALTWTP 954
+ V + E S ++ +++RP P + V ++D G+ V + W
Sbjct: 239 -VCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWR- 296
Query: 955 PKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLS 1014
KDDG + Y I+ +H + I ++ G+ + +ENM G +
Sbjct: 297 -KDDGELPKSRYEIRD------------DH----TLKIRKVTAGDMGSYTCVAENMVGKA 339
Query: 1015 E-DATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGN 1073
E AT+T + E P F + G T C GN
Sbjct: 340 EASATLTVQ----------------------EPPHFVVKPRDQVVALGRTVTFQCEATGN 377
Query: 1074 PKPKITWMK----NKVAIVDDPR-YRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTV 1128
P+P I W + N + P+ FS L I D G Y C+ +N G++
Sbjct: 378 PQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSI 437
Query: 1129 EIECKLEV 1136
+ LEV
Sbjct: 438 ITKAYLEV 445
Score = 49.7 bits (117), Expect = 2e-05
Identities = 71/321 (22%), Positives = 122/321 (38%), Gaps = 58/321 (18%)
Query: 836 PPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSE---- 891
PP RI H + + GE L +G+P P + W K G ++ ++ + R+
Sbjct: 67 PP--RIVEHPSDLIVSK-GEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLP 123
Query: 892 TDTIIFIR----KAERSHSGKYDLQVKV---DKFVETASIDIQIID---RPGPPQIVKIE 941
+ ++ F+R + R G Y + + AS+++ I+ R P ++
Sbjct: 124 SGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAV 183
Query: 942 DVWGENVALTWTPPKDDGNAAIT----GYTIQKADKK-SMEWFTVIEHYHRTSATITELV 996
GE + PP+ I+ G + D++ ++ ++ Y R S +
Sbjct: 184 ---GEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVC 240
Query: 997 IGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNT 1056
+G NM G +ES V + E P F + N
Sbjct: 241 VGT---------NMVG-------ERESEVA-------------ELTVLERPSFVKRPSNL 271
Query: 1057 YAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGT 1116
+A C RG+P P + W K+ + RY + + TL+IRK + D G+
Sbjct: 272 AVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKS-RYEIRDDH---TLKIRKVTAGDMGS 327
Query: 1117 YCCKAVNDLGTVEIECKLEVK 1137
Y C A N +G E L V+
Sbjct: 328 YTCVAENMVGKAEASATLTVQ 348
Score = 48.9 bits (115), Expect = 3e-05
Identities = 84/349 (24%), Positives = 133/349 (38%), Gaps = 51/349 (14%)
Query: 802 TDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVI 861
+DA +V V N G E + +L + P ++ P +L T V ++
Sbjct: 233 SDAGKYVCV-GTNMVGERESEVAELTVLER----PSFVKRPSNLAVT----VDDSAEFKC 283
Query: 862 PFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVK--VDKFV 919
+G P P + W+KD E+ K++ IR+ T + IRK G Y + V K
Sbjct: 284 EARGDPVPTVRWRKDDGELPKSRYEIRDDHT---LKIRKVTAGDMGSYTCVAENMVGKAE 340
Query: 920 ETASIDIQIIDRPGPPQ-IVKIEDVWGENVALTWTPP---KDDGNAAITGYTIQKADKKS 975
+A++ +Q PP +VK D + VAL T + GN + ++ +
Sbjct: 341 ASATLTVQ-----EPPHFVVKPRD---QVVALGRTVTFQCEATGNPQPAIFWRREGSQNL 392
Query: 976 MEWFTVIEHYHRTSA------TITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARD 1029
+ + + R S TIT + + Y+ + N+ G + + VIA
Sbjct: 393 LFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIAD- 451
Query: 1030 GKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAI-V 1088
P+ Q VN L+C G+P P I W K+ V +
Sbjct: 452 --------------RPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVST 497
Query: 1089 DDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1137
D R + N GV L+IR D G Y C A G +EV+
Sbjct: 498 QDSRIKQLEN-GV--LQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQ 543
Score = 42.7 bits (99), Expect = 0.002
Identities = 34/88 (38%), Positives = 40/88 (45%), Gaps = 10/88 (11%)
Query: 1061 GYNATLNCSVRGNPKPKITWMKNKVAI---VDDPR-YRMFSNQG----VCTLEIRKPSPY 1112
G ATLNC G P P I W K + DDPR +RM G + + RK P
Sbjct: 82 GEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRP- 140
Query: 1113 DGGTYCCKAVNDLG-TVEIECKLEVKVI 1139
D G Y C A N LG V LEV ++
Sbjct: 141 DEGVYVCVARNYLGEAVSHNASLEVAIL 168
>gi|140560919 myomesin 1 isoform a [Homo sapiens]
Length = 1685
Score = 105 bits (261), Expect = 3e-22
Identities = 85/322 (26%), Positives = 133/322 (41%), Gaps = 58/322 (18%)
Query: 555 PKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKN----EAGEAHA 610
P+ W R + S ++T + +TL ++D G+Y I ++ E A+
Sbjct: 439 PEIQWYRNGVPLSP-SKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYV 497
Query: 611 SIKVKVVDFPDPPVAPT---VTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWM 667
++ + P AP E D+ I++W+ PA DGGSPILGYFI++ + + W
Sbjct: 498 FVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWS 557
Query: 668 RLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPL------------ 715
+ N K F +IEG +Y R+ AVN +GI PS S P L
Sbjct: 558 QCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRP 617
Query: 716 ------------------AVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 757
V PPT L+V T + V + W+PP G G+ Y +E C
Sbjct: 618 SAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGI-MYFVEKC 676
Query: 758 FEGSTSAKQSDENGEAAYDLPAEDWIVANKDL-IDKTKFTITGLPTDAKIFVRVKAVNAA 816
G+ E+W N +L + +F + L RV+ N+A
Sbjct: 677 EAGT------------------ENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSA 718
Query: 817 GASEPKYYSQPILVKEIIEPPK 838
G EP ++ +V + ++ PK
Sbjct: 719 GVGEPSEATEVTVVGDKLDIPK 740
Score = 104 bits (259), Expect = 5e-22
Identities = 181/777 (23%), Positives = 287/777 (36%), Gaps = 143/777 (18%)
Query: 352 TAYCGERVELECEVSE-DDANVKWFKNGEEI-IPGPKSRYRIRVEGKKHILIIEGATKAD 409
T + E V+L C ++ + V W+KN I + +Y I H L I G D
Sbjct: 287 TVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFED 346
Query: 410 AAEY--SVMTTGGQSSAKLSVDLK------------------PLKI-LTPL--------- 439
A+Y S M G+ SA SV +K PL +TP
Sbjct: 347 TAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIH 406
Query: 440 -----------TDQTVNLGKEICLKCEISENIPG-KWTKNGLPVQESDRLKVVHKGRIHK 487
+T++LG + + EI P +W +NG+P+ S ++ + G
Sbjct: 407 FDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERAT 466
Query: 488 LVIANALTEDEG---------DYVFAPDAYNVTLPAKVHVIDPPKIILDG--LDADNTVT 536
L ++ EDEG +Y AY A + P LD L+A+
Sbjct: 467 LTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYI 526
Query: 537 VIAGNKLRLE--IPISGEPPPKA-----MWSRGDK-----AIMEGSGRIRTESYPDSSTL 584
+I+ + ++ PI G K WS+ + A +G I SY
Sbjct: 527 IISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRA 586
Query: 585 V----IDIAERDDSGVYHINLKNEAG-----EAHASIKVKVVD-------FPDPPVAPTV 628
V I R V ++ +A A + ++ V + P PP +V
Sbjct: 587 VNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSV 646
Query: 629 TEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDL-CKETTFEPKKMIEG 687
TE + +++W+PP G I+ YF+E+ + + W R+N +L K F + EG
Sbjct: 647 TEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEG 705
Query: 688 VAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHI 744
+Y R+ N+ G+ +PS + V L + P + TDT+V + W +
Sbjct: 706 KSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWE--ESK 763
Query: 745 GAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDA 804
A L GY +E GS W N + + ++FT GL T
Sbjct: 764 DAKELVGYYIEASVAGSGK------------------WEPCNNNPVKGSRFTCHGLVTGQ 805
Query: 805 KIFVRVKAVNAAGASEPKYYSQPILVKEII--------------EPPKIRIPRHLKQTYI 850
RV+AVNAAG SE S+ I VK I EP + R
Sbjct: 806 SYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEAS 865
Query: 851 RRVGEAVNLVIPFQGKPR-PELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKY 909
+ L+ KP P + E+ K ++ T +KA K
Sbjct: 866 PPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPP---PQKAAPQGKSKS 922
Query: 910 D-LQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTI 968
D L+ K D+ P PP + + + +++ L W P G A ITGY +
Sbjct: 923 DPLKKKTDR------------APPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYV 970
Query: 969 ---QKADKKSMEWFTV-IEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTK 1021
+ D +W ++ + I+ L Y F+V + NM GL + +++
Sbjct: 971 NYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSE 1027
Score = 89.4 bits (220), Expect = 2e-17
Identities = 120/552 (21%), Positives = 205/552 (37%), Gaps = 79/552 (14%)
Query: 620 PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSS---RWMRLNFDLCKE 676
P PP T E D ++ W+ P GG+ I GY++ ++ +W N E
Sbjct: 934 PSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSE 993
Query: 677 TTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV----PLAVTSPPTLLTVDSVTDT 732
++ + E + Y+ ++ A+N G+ PS S F +AV PP L V
Sbjct: 994 EAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKD 1053
Query: 733 TVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDK 792
++ ++W+PP H G + GY ++ AK+ + W N+ I
Sbjct: 1054 SLVLQWKPPVHSGRTPVTGYFVDL---KEAKAKE-------------DQWRGLNEAAIKN 1097
Query: 793 TKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRR 852
+ GL RV+A+N AG +P + P++ + R + +
Sbjct: 1098 VYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAE----------TRPGTKEVVVN 1147
Query: 853 VGEAVNLVIPFQ---GKPRPELTWKKDGAEI-DKNQINIRNSETDTIIFIRKAERSHSGK 908
V + + + F+ P+ E +W KD D ++ + + T + + G
Sbjct: 1148 VDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGI 1207
Query: 909 YDLQV-KVDKFVETASIDIQIIDR----------PGPP--QIVKIEDVWGENVALTWTPP 955
Y V D + ID + + R P P + +E + V
Sbjct: 1208 YSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAE 1267
Query: 956 KDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL-- 1013
K GNA + Y +K+ E H R + I E + + G
Sbjct: 1268 KLSGNAKV-NYIFN--EKEIFEGPKYKMHIDRNTGII-------EMFMEKLQDEDEGTYT 1317
Query: 1014 --SEDATMTKESAVIARDGKIYKNPVYEDFDF-------SEAPMFTQPLVNTYAIAG-YN 1063
+D T S V+ G ++K + ++ +F + P F + L ++ + G N
Sbjct: 1318 FQLQDGKATNHSTVVL-VGDVFKK-LQKEAEFQRQEWIRKQGPHFVEYL--SWEVTGECN 1373
Query: 1064 ATLNCSVRGNPK-PKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAV 1122
L C V K I W K++ I D ++ G+CTL I + S D G Y
Sbjct: 1374 VLLKCKVANIKKETHIVWYKDEREISVDEKHDF--KDGICTLLITEFSKKDAGIYEVILK 1431
Query: 1123 NDLGTVEIECKL 1134
+D G + KL
Sbjct: 1432 DDRGKDKSRLKL 1443
Score = 57.4 bits (137), Expect = 8e-08
Identities = 101/453 (22%), Positives = 166/453 (36%), Gaps = 92/453 (20%)
Query: 238 LKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVV--ELADPKLEVKWYKNGQEIRPS 295
LKRL + E K K + A ++ + G+VRF + E +V + N +EI
Sbjct: 1229 LKRLLALSHEHKFPTVPVKS-ELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFEG 1287
Query: 296 TKY---IFEHKGCQRILFINNCQMTDDSEYYVTAGDEKC---STELFVREPPIMVTKQLE 349
KY I + G +F+ Q D+ Y D K ST + V + + K+ E
Sbjct: 1288 PKYKMHIDRNTGIIE-MFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQKEAE 1346
Query: 350 --------------------DTTAYCGERVELECEVS--EDDANVKWFKNGEEIIPGPKS 387
+ T C V L+C+V+ + + ++ W+K+ EI K
Sbjct: 1347 FQRQEWIRKQGPHFVEYLSWEVTGECN--VLLKCKVANIKKETHIVWYKDEREISVDEKH 1404
Query: 388 RYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLG 447
++ +G +LI E +K DA Y V+ + K + L + + L
Sbjct: 1405 DFK---DGICTLLITE-FSKKDAGIYEVILKDDRGKDKSRLKL--------VDEAFKELM 1452
Query: 448 KEICLKCEIS-----------------------ENIPGKWTKNGLPVQESDRLKVVHKGR 484
E+C K +S E++ W+ NG ++ SDR+K G
Sbjct: 1453 MEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGE 1512
Query: 485 IHKLVIANALTEDEGDYVF----APDAYNVTLPAKVHVIDPPKI---------------- 524
L I D+G YV + T+ D
Sbjct: 1513 QIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRA 1572
Query: 525 -ILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSST 583
+L GL + VT+ G L L + G+PPP+ W + +KA+ ++
Sbjct: 1573 RVLGGL--PDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAY 1630
Query: 584 LVIDIAERDDSGVYHINLKNEAGEAHASIKVKV 616
I+ DSG Y + +KN+ G + V V
Sbjct: 1631 FTINGVSTADSGKYGLVVKNKYGSETSDFTVSV 1663
Score = 51.6 bits (122), Expect = 4e-06
Identities = 38/169 (22%), Positives = 76/169 (44%), Gaps = 11/169 (6%)
Query: 868 RPELTWKKDGAEIDKNQI--NIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASI- 924
+PE+ W ++G + ++ + + E T+ F + G Y ++V++ ++ E S
Sbjct: 438 QPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSH-LNKEDEGLYTIRVRMGEYYEQYSAY 496
Query: 925 ------DIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEW 978
D +I P P VK + + + ++W P DG + I GY I K + + W
Sbjct: 497 VFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSW 556
Query: 979 FTVIEHYHRTSA-TITELVIGNEYYFRVFSENMCGLSEDATMTKESAVI 1026
+ + + +T L+ G Y FRV + N G+ + +++ A +
Sbjct: 557 SQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAAL 605
Score = 45.8 bits (107), Expect = 2e-04
Identities = 27/78 (34%), Positives = 40/78 (51%), Gaps = 3/78 (3%)
Query: 1063 NATLNCSVRGNPKPKITWMKNKVAI---VDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCC 1119
N L+CS+ G P+P++TW KN+V I + +Y + S G+ TLEI D Y
Sbjct: 293 NVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRA 352
Query: 1120 KAVNDLGTVEIECKLEVK 1137
A+N G + + VK
Sbjct: 353 SAMNVKGELSAYASVVVK 370
Score = 43.1 bits (100), Expect = 0.001
Identities = 27/96 (28%), Positives = 42/96 (43%), Gaps = 3/96 (3%)
Query: 932 PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSA- 990
PGPP + + + V L+W PP G+ I Y ++K + + W V S
Sbjct: 638 PGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPR 696
Query: 991 -TITELVIGNEYYFRVFSENMCGLSEDATMTKESAV 1025
+ +L G Y FRV N G+ E + T+ + V
Sbjct: 697 FALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVV 732
Score = 40.8 bits (94), Expect = 0.007
Identities = 35/139 (25%), Positives = 62/139 (44%), Gaps = 4/139 (2%)
Query: 811 KAVNAAGASEPKYYSQPILVKE--IIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPR 868
K V+ +G + + Y++ +K+ I E + R+ L + G+A+NL G P
Sbjct: 1542 KTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPP 1601
Query: 869 PELTW-KKDGAEIDKNQINIRNSETDTIIF-IRKAERSHSGKYDLQVKVDKFVETASIDI 926
PE++W K + A + N++ T F I + SGKY L VK ET+ +
Sbjct: 1602 PEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTV 1661
Query: 927 QIIDRPGPPQIVKIEDVWG 945
+ ++ +E + G
Sbjct: 1662 SVFIPEEEARMAALESLKG 1680
Score = 36.2 bits (82), Expect = 0.18
Identities = 38/147 (25%), Positives = 61/147 (41%), Gaps = 17/147 (11%)
Query: 473 ESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDAD 532
E KVV + + +L + L E E Y+ L H++ P+ I+
Sbjct: 237 EKKSRKVVIREKAERLSLRKTLEETE--------TYHAKLNED-HLLHAPEFIIK----P 283
Query: 533 NTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAI--MEGSGRIRTESYPDSSTLVIDIAE 590
+ TV ++L I+G P P+ W + I G+ ES TL I+ +
Sbjct: 284 RSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCD 343
Query: 591 RDDSGVYHINLKNEAGE--AHASIKVK 615
+D+ Y + N GE A+AS+ VK
Sbjct: 344 FEDTAQYRASAMNVKGELSAYASVVVK 370
Score = 36.2 bits (82), Expect = 0.18
Identities = 20/68 (29%), Positives = 30/68 (44%), Gaps = 1/68 (1%)
Query: 1061 GYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRM-FSNQGVCTLEIRKPSPYDGGTYCC 1119
G L C+V G+P P+++W+KN+ A+ D + F I S D G Y
Sbjct: 1587 GKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGL 1646
Query: 1120 KAVNDLGT 1127
N G+
Sbjct: 1647 VVKNKYGS 1654
Score = 30.8 bits (68), Expect = 7.7
Identities = 41/180 (22%), Positives = 68/180 (37%), Gaps = 21/180 (11%)
Query: 270 VRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYY--VTAG 327
+ F + PK E W K+ S + E KG + + + M D Y VT
Sbjct: 1156 LNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDT 1215
Query: 328 DEKCSTELFVRE--------------PPIMVTKQLEDTTAYCGE-RVELECEVSEDDANV 372
D S+ L E P + V +L G+ R ++ E +A V
Sbjct: 1216 DGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKV 1275
Query: 373 KWFKNGEEIIPGPKSRYRIRVEGKKHI--LIIEGATKADAAEYSVMTTGGQSSAKLSVDL 430
+ N +EI GPK Y++ ++ I + +E D Y+ G+++ +V L
Sbjct: 1276 NYIFNEKEIFEGPK--YKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVL 1333
>gi|224994173 roundabout 1 isoform d [Homo sapiens]
Length = 1551
Score = 102 bits (255), Expect = 2e-21
Identities = 125/478 (26%), Positives = 180/478 (37%), Gaps = 66/478 (13%)
Query: 279 PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGD------EKCS 332
P+ + W K+G + + I G I + D+ YV G E
Sbjct: 159 PEPTISWKKDGSPLDDKDERITIRGGKLMITYTRK----SDAGKYVCVGTNMVGERESEV 214
Query: 333 TELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDA-NVKWFKNGEEIIPGPKSRYRI 391
EL V E P V K+ + + E +CE D V+W K+ E+ PKSRY I
Sbjct: 215 AELTVLERPSFV-KRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGEL---PKSRYEI 270
Query: 392 RVEGKKHILIIEGATKADAAEYSV----MTTGGQSSAKLSVDL--KPLKILTPLTDQTVN 445
R + H L I T D Y+ M ++SA L+V + +P + DQ V
Sbjct: 271 RDD---HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEPPHFVVKPRDQVVA 327
Query: 446 LGKEICLKCEISENIPGK--WTKNGL--------PVQESDRLKVVHKGRIHKLVIANALT 495
LG+ + +CE + N W + G P Q S R V G L I N
Sbjct: 328 LGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTG---DLTITNVQR 384
Query: 496 EDEGDYVFAP--DAYNVTLPAKVHVID-----PPKIILDGLDADNTVTVIAGNKLRLEIP 548
D G Y+ A ++ A + V D PP +I G TV L
Sbjct: 385 SDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQG---PVNQTVAVDGTFVLSCV 441
Query: 549 ISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEA 608
+G P P +W + + RI+ ++ L I A+ D+G Y +GEA
Sbjct: 442 ATGSPVPTILWRKDGVLVSTQDSRIKQL---ENGVLQIRYAKLGDTGRYTCIASTPSGEA 498
Query: 609 HASIKVKVVDF---------------PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILG 653
S ++V +F P P P VT+V + ++W+P G +P
Sbjct: 499 TWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATP-TS 557
Query: 654 YFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRP 711
Y IE S + + K T K + Y + A NA GIS PS S P
Sbjct: 558 YIIEAFSHASGSSWQTVAENVKTETSAIKGLKPNAIYLFLVRAANAYGISDPSQISDP 615
Score = 72.4 bits (176), Expect = 2e-12
Identities = 182/788 (23%), Positives = 289/788 (36%), Gaps = 130/788 (16%)
Query: 350 DTTAYCGERVELECEV--SEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATK 407
D GE +EC+ + + W K+G P RI + G K L+I K
Sbjct: 139 DVMVAVGEPAVMECQPPRGHPEPTISWKKDGS---PLDDKDERITIRGGK--LMITYTRK 193
Query: 408 ADAAEYSVMTT---GGQSS--AKLSVDLKPLKILTPLTDQTVNLGKEICLKCEI-SENIP 461
+DA +Y + T G + S A+L+V +P + P ++ V + KCE + +P
Sbjct: 194 SDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRP-SNLAVTVDDSAEFKCEARGDPVP 252
Query: 462 G-KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAY------NVTLPA 514
+W K+ + +S R ++ H L I D G Y + + TL
Sbjct: 253 TVRWRKDDGELPKS-RYEIRDD---HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV 308
Query: 515 KVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIR 574
+V +PP ++ D V G + + +G P P W R EGS +
Sbjct: 309 QVGS-EPPHFVVKPRDQ----VVALGRTVTFQCEATGNPQPAIFWRR------EGSQNLL 357
Query: 575 TESYPDSST----------LVIDIAERDDSGVYHINLKNEAG----EAHASIKVKVVDFP 620
P S+ L I +R D G Y N AG +A+ + + D P
Sbjct: 358 FSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRP 417
Query: 621 DP-----PVAPTVTEVGDDW--CIMNWEPPA---YDGGSPILGYFIERKKKQSSRWMRLN 670
P PV TV G C+ P + ++ R K+ + +++
Sbjct: 418 PPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIR 477
Query: 671 FDLCKET------TFEPKKMIEGVAY-EVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTL 723
+ +T P AY EV+ F V P P RP P + S P+
Sbjct: 478 YAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGV-------PVQPPRPTDPNLIPSAPSK 530
Query: 724 LTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWI 783
V V+ TVT+ W+P + GA Y++E S S+ W
Sbjct: 531 PEVTDVSRNTVTLSWQPNLNSGATP-TSYIIEAFSHASGSS-----------------WQ 572
Query: 784 VANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPR 843
+++ +T I GL +A V+A NA G S+P S P+ ++++ P +
Sbjct: 573 TVAENVKTETS-AIKGLKPNAIYLFLVRAANAYGISDPSQISDPVKTQDVL-PTSQGVDH 630
Query: 844 HLKQTYIRRVGEAV-NLVIP-FQGKPRPELTWKKD-------GAEIDKNQINIRNSETDT 894
Q R +G AV +L P E+ W D G +I + E+D
Sbjct: 631 KQVQ---RELGNAVLHLHNPTVLSSSSIEVHWTVDQQSQYIQGYKILYRPSGANHGESDW 687
Query: 895 IIF-IRKAERSHSGKYDLQVKVDK-------FVETASIDIQI------IDRP-GPPQIVK 939
++F +R ++ DL+ V+ F E D +I + P PPQ V
Sbjct: 688 LVFEVRTPAKNSVVIPDLRKGVNYEIKARPFFNEFQGADSEIKFAKTLEEAPSAPPQGVT 747
Query: 940 I--EDVWGENVALTWTPPKDD-GNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELV 996
+ D G + ++W PP +D N + Y + ++ S I LV
Sbjct: 748 VSKNDGNGTAILVSWQPPPEDTQNGMVQEYKVWCLGNETRYHINKTVDGSTFSVVIPFLV 807
Query: 997 IGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNT 1056
G Y V + G + + E I D + NPV + S A + +
Sbjct: 808 PGIRYSVEVAASTGAG----SGVKSEPQFIQLDA--HGNPVSPEDQVSLAQQISDVVKQP 861
Query: 1057 YAIAGYNA 1064
IAG A
Sbjct: 862 AFIAGIGA 869
Score = 62.8 bits (151), Expect = 2e-09
Identities = 143/636 (22%), Positives = 238/636 (37%), Gaps = 77/636 (12%)
Query: 422 SSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPG---KWTKNGLPVQ------ 472
S ++L + P +I+ +D V+ G+ L C+ +E P +W K G V+
Sbjct: 18 SGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCK-AEGRPTPTIEWYKGGERVETDKDDP 76
Query: 473 ESDRLKVVHKGRIHKLVIANALTE--DEGDYVFAPDAYNVTLPAKVHVIDPPKIIL--DG 528
S R+ ++ G + L I + DEG YV A N A H IL D
Sbjct: 77 RSHRM-LLPSGSLFFLRIVHGRKSRPDEGVYVCV--ARNYLGEAVSHNASLEVAILRDDF 133
Query: 529 LDADNTVTVIAGNKLRLEI-PISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVID 587
+ V V G +E P G P P W + + + RI L+I
Sbjct: 134 RQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRG----GKLMIT 189
Query: 588 IAERDDSGVYHINLKNEAGEAHASI-KVKVVDFPD-----PPVAPTVTEVGDDWCIMNWE 641
+ D+G Y N GE + + ++ V++ P +A TV + + C +
Sbjct: 190 YTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGD 249
Query: 642 PPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIG 701
P R +K + +++ + T + +K+ G A N +G
Sbjct: 250 PVP-----------TVRWRKDDGELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVG 298
Query: 702 ISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGS 761
++ S + + V S P V D V + A G + + EGS
Sbjct: 299 KAEASAT----LTVQVGSEPPHFVVKP-RDQVVALGRTVTFQCEATGNPQPAIFWRREGS 353
Query: 762 TSAKQSDENGEAAYDLPAEDWIVANKDLIDKT-KFTITGLPTDAKIFVRVKAVNAAGASE 820
+N +Y P +++ + +T TIT + + + +N AG+
Sbjct: 354 -------QNLLFSYQPPQS----SSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSII 402
Query: 821 PKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI 880
K Y + V PP IR + QT V L G P P + W+KDG +
Sbjct: 403 TKAYLEVTDVIADRPPPVIR-QGPVNQTVA--VDGTFVLSCVATGSPVPTILWRKDGVLV 459
Query: 881 DKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIID--------RP 932
I+ E + ++ IR A+ +G+Y T S I++ + RP
Sbjct: 460 STQDSRIKQLE-NGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRP 518
Query: 933 GPPQIV-------KIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKS-MEWFTVIEH 984
P ++ ++ DV V L+W P + G A T Y I+ S W TV E+
Sbjct: 519 TDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSG-ATPTSYIIEAFSHASGSSWQTVAEN 577
Query: 985 YHRTSATITELVIGNEYYFRVFSENMCGLSEDATMT 1020
++ I L Y F V + N G+S+ + ++
Sbjct: 578 VKTETSAIKGLKPNAIYLFLVRAANAYGISDPSQIS 613
Score = 56.2 bits (134), Expect = 2e-07
Identities = 79/308 (25%), Positives = 123/308 (39%), Gaps = 66/308 (21%)
Query: 853 VGE-AVNLVIPFQGKPRPELTWKKDGAEID--KNQINIRNSETDTIIFIRKAERSHSGKY 909
VGE AV P +G P P ++WKKDG+ +D +I IR + + I +S +GKY
Sbjct: 144 VGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGK----LMITYTRKSDAGKY 199
Query: 910 DLQVKVDKFVETAS--IDIQIIDRPG----PPQI-VKIED-------VWGENV-ALTWTP 954
+ V + E S ++ +++RP P + V ++D G+ V + W
Sbjct: 200 -VCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWR- 257
Query: 955 PKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLS 1014
KDDG + Y I+ +H + I ++ G+ + +ENM G +
Sbjct: 258 -KDDGELPKSRYEIRD------------DH----TLKIRKVTAGDMGSYTCVAENMVGKA 300
Query: 1015 E-DATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGN 1073
E AT+T + SE P F + G T C GN
Sbjct: 301 EASATLTVQVG-------------------SEPPHFVVKPRDQVVALGRTVTFQCEATGN 341
Query: 1074 PKPKITWMK----NKVAIVDDPR-YRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTV 1128
P+P I W + N + P+ FS L I D G Y C+ +N G++
Sbjct: 342 PQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSI 401
Query: 1129 EIECKLEV 1136
+ LEV
Sbjct: 402 ITKAYLEV 409
Score = 53.5 bits (127), Expect = 1e-06
Identities = 84/348 (24%), Positives = 134/348 (38%), Gaps = 46/348 (13%)
Query: 802 TDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVI 861
+DA +V V N G E + +L + P ++ P +L T V ++
Sbjct: 194 SDAGKYVCV-GTNMVGERESEVAELTVLER----PSFVKRPSNLAVT----VDDSAEFKC 244
Query: 862 PFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVK--VDKFV 919
+G P P + W+KD E+ K++ IR+ T + IRK G Y + V K
Sbjct: 245 EARGDPVPTVRWRKDDGELPKSRYEIRDDHT---LKIRKVTAGDMGSYTCVAENMVGKAE 301
Query: 920 ETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPP---KDDGNAAITGYTIQKADKKSM 976
+A++ +Q+ P P +VK D + VAL T + GN + ++ + +
Sbjct: 302 ASATLTVQVGSEP-PHFVVKPRD---QVVALGRTVTFQCEATGNPQPAIFWRREGSQNLL 357
Query: 977 EWFTVIEHYHRTSA------TITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDG 1030
+ + R S TIT + + Y+ + N+ G + + VIA
Sbjct: 358 FSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIAD-- 415
Query: 1031 KIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAI-VD 1089
P+ Q VN L+C G+P P I W K+ V +
Sbjct: 416 -------------RPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQ 462
Query: 1090 DPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1137
D R + N GV L+IR D G Y C A G +EV+
Sbjct: 463 DSRIKQLEN-GV--LQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQ 507
Score = 51.2 bits (121), Expect = 5e-06
Identities = 72/322 (22%), Positives = 123/322 (38%), Gaps = 58/322 (18%)
Query: 836 PPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSE---- 891
PP RI H + + GE L +G+P P + W K G ++ ++ + R+
Sbjct: 28 PP--RIVEHPSDLIVSK-GEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLP 84
Query: 892 TDTIIFIR----KAERSHSGKYDLQVKV---DKFVETASIDIQIID---RPGPPQIVKIE 941
+ ++ F+R + R G Y + + AS+++ I+ R P ++
Sbjct: 85 SGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAV 144
Query: 942 DVWGENVALTWTPPKDDGNAAIT----GYTIQKADKK-SMEWFTVIEHYHRTSATITELV 996
GE + PP+ I+ G + D++ ++ ++ Y R S +
Sbjct: 145 ---GEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVC 201
Query: 997 IGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNT 1056
+G NM G +ES V + E P F + N
Sbjct: 202 VGT---------NMVG-------ERESEVA-------------ELTVLERPSFVKRPSNL 232
Query: 1057 YAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGT 1116
+A C RG+P P + W K+ + RY + + TL+IRK + D G+
Sbjct: 233 AVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKS-RYEIRDDH---TLKIRKVTAGDMGS 288
Query: 1117 YCCKAVNDLGTVEIECKLEVKV 1138
Y C A N +G E L V+V
Sbjct: 289 YTCVAENMVGKAEASATLTVQV 310
Score = 42.7 bits (99), Expect = 0.002
Identities = 34/88 (38%), Positives = 40/88 (45%), Gaps = 10/88 (11%)
Query: 1061 GYNATLNCSVRGNPKPKITWMKNKVAI---VDDPR-YRMFSNQG----VCTLEIRKPSPY 1112
G ATLNC G P P I W K + DDPR +RM G + + RK P
Sbjct: 43 GEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRP- 101
Query: 1113 DGGTYCCKAVNDLG-TVEIECKLEVKVI 1139
D G Y C A N LG V LEV ++
Sbjct: 102 DEGVYVCVARNYLGEAVSHNASLEVAIL 129
>gi|224994171 roundabout 1 isoform c [Homo sapiens]
Length = 1606
Score = 102 bits (255), Expect = 2e-21
Identities = 125/478 (26%), Positives = 180/478 (37%), Gaps = 66/478 (13%)
Query: 279 PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGD------EKCS 332
P+ + W K+G + + I G I + D+ YV G E
Sbjct: 159 PEPTISWKKDGSPLDDKDERITIRGGKLMITYTRK----SDAGKYVCVGTNMVGERESEV 214
Query: 333 TELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDA-NVKWFKNGEEIIPGPKSRYRI 391
EL V E P V K+ + + E +CE D V+W K+ E+ PKSRY I
Sbjct: 215 AELTVLERPSFV-KRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGEL---PKSRYEI 270
Query: 392 RVEGKKHILIIEGATKADAAEYSV----MTTGGQSSAKLSVDL--KPLKILTPLTDQTVN 445
R + H L I T D Y+ M ++SA L+V + +P + DQ V
Sbjct: 271 RDD---HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEPPHFVVKPRDQVVA 327
Query: 446 LGKEICLKCEISENIPGK--WTKNGL--------PVQESDRLKVVHKGRIHKLVIANALT 495
LG+ + +CE + N W + G P Q S R V G L I N
Sbjct: 328 LGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTG---DLTITNVQR 384
Query: 496 EDEGDYVFAP--DAYNVTLPAKVHVID-----PPKIILDGLDADNTVTVIAGNKLRLEIP 548
D G Y+ A ++ A + V D PP +I G TV L
Sbjct: 385 SDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQG---PVNQTVAVDGTFVLSCV 441
Query: 549 ISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEA 608
+G P P +W + + RI+ ++ L I A+ D+G Y +GEA
Sbjct: 442 ATGSPVPTILWRKDGVLVSTQDSRIKQL---ENGVLQIRYAKLGDTGRYTCIASTPSGEA 498
Query: 609 HASIKVKVVDF---------------PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILG 653
S ++V +F P P P VT+V + ++W+P G +P
Sbjct: 499 TWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATP-TS 557
Query: 654 YFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRP 711
Y IE S + + K T K + Y + A NA GIS PS S P
Sbjct: 558 YIIEAFSHASGSSWQTVAENVKTETSAIKGLKPNAIYLFLVRAANAYGISDPSQISDP 615
Score = 72.4 bits (176), Expect = 2e-12
Identities = 182/788 (23%), Positives = 289/788 (36%), Gaps = 130/788 (16%)
Query: 350 DTTAYCGERVELECEV--SEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATK 407
D GE +EC+ + + W K+G P RI + G K L+I K
Sbjct: 139 DVMVAVGEPAVMECQPPRGHPEPTISWKKDGS---PLDDKDERITIRGGK--LMITYTRK 193
Query: 408 ADAAEYSVMTT---GGQSS--AKLSVDLKPLKILTPLTDQTVNLGKEICLKCEI-SENIP 461
+DA +Y + T G + S A+L+V +P + P ++ V + KCE + +P
Sbjct: 194 SDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRP-SNLAVTVDDSAEFKCEARGDPVP 252
Query: 462 G-KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAY------NVTLPA 514
+W K+ + +S R ++ H L I D G Y + + TL
Sbjct: 253 TVRWRKDDGELPKS-RYEIRDD---HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV 308
Query: 515 KVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIR 574
+V +PP ++ D V G + + +G P P W R EGS +
Sbjct: 309 QVGS-EPPHFVVKPRDQ----VVALGRTVTFQCEATGNPQPAIFWRR------EGSQNLL 357
Query: 575 TESYPDSST----------LVIDIAERDDSGVYHINLKNEAG----EAHASIKVKVVDFP 620
P S+ L I +R D G Y N AG +A+ + + D P
Sbjct: 358 FSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRP 417
Query: 621 DP-----PVAPTVTEVGDDW--CIMNWEPPA---YDGGSPILGYFIERKKKQSSRWMRLN 670
P PV TV G C+ P + ++ R K+ + +++
Sbjct: 418 PPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIR 477
Query: 671 FDLCKET------TFEPKKMIEGVAY-EVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTL 723
+ +T P AY EV+ F V P P RP P + S P+
Sbjct: 478 YAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGV-------PVQPPRPTDPNLIPSAPSK 530
Query: 724 LTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWI 783
V V+ TVT+ W+P + GA Y++E S S+ W
Sbjct: 531 PEVTDVSRNTVTLSWQPNLNSGATP-TSYIIEAFSHASGSS-----------------WQ 572
Query: 784 VANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPR 843
+++ +T I GL +A V+A NA G S+P S P+ ++++ P +
Sbjct: 573 TVAENVKTETS-AIKGLKPNAIYLFLVRAANAYGISDPSQISDPVKTQDVL-PTSQGVDH 630
Query: 844 HLKQTYIRRVGEAV-NLVIP-FQGKPRPELTWKKD-------GAEIDKNQINIRNSETDT 894
Q R +G AV +L P E+ W D G +I + E+D
Sbjct: 631 KQVQ---RELGNAVLHLHNPTVLSSSSIEVHWTVDQQSQYIQGYKILYRPSGANHGESDW 687
Query: 895 IIF-IRKAERSHSGKYDLQVKVDK-------FVETASIDIQI------IDRP-GPPQIVK 939
++F +R ++ DL+ V+ F E D +I + P PPQ V
Sbjct: 688 LVFEVRTPAKNSVVIPDLRKGVNYEIKARPFFNEFQGADSEIKFAKTLEEAPSAPPQGVT 747
Query: 940 I--EDVWGENVALTWTPPKDD-GNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELV 996
+ D G + ++W PP +D N + Y + ++ S I LV
Sbjct: 748 VSKNDGNGTAILVSWQPPPEDTQNGMVQEYKVWCLGNETRYHINKTVDGSTFSVVIPFLV 807
Query: 997 IGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNT 1056
G Y V + G + + E I D + NPV + S A + +
Sbjct: 808 PGIRYSVEVAASTGAG----SGVKSEPQFIQLDA--HGNPVSPEDQVSLAQQISDVVKQP 861
Query: 1057 YAIAGYNA 1064
IAG A
Sbjct: 862 AFIAGIGA 869
Score = 62.8 bits (151), Expect = 2e-09
Identities = 143/636 (22%), Positives = 238/636 (37%), Gaps = 77/636 (12%)
Query: 422 SSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPG---KWTKNGLPVQ------ 472
S ++L + P +I+ +D V+ G+ L C+ +E P +W K G V+
Sbjct: 18 SGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCK-AEGRPTPTIEWYKGGERVETDKDDP 76
Query: 473 ESDRLKVVHKGRIHKLVIANALTE--DEGDYVFAPDAYNVTLPAKVHVIDPPKIIL--DG 528
S R+ ++ G + L I + DEG YV A N A H IL D
Sbjct: 77 RSHRM-LLPSGSLFFLRIVHGRKSRPDEGVYVCV--ARNYLGEAVSHNASLEVAILRDDF 133
Query: 529 LDADNTVTVIAGNKLRLEI-PISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVID 587
+ V V G +E P G P P W + + + RI L+I
Sbjct: 134 RQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRG----GKLMIT 189
Query: 588 IAERDDSGVYHINLKNEAGEAHASI-KVKVVDFPD-----PPVAPTVTEVGDDWCIMNWE 641
+ D+G Y N GE + + ++ V++ P +A TV + + C +
Sbjct: 190 YTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGD 249
Query: 642 PPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIG 701
P R +K + +++ + T + +K+ G A N +G
Sbjct: 250 PVP-----------TVRWRKDDGELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVG 298
Query: 702 ISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGS 761
++ S + + V S P V D V + A G + + EGS
Sbjct: 299 KAEASAT----LTVQVGSEPPHFVVKP-RDQVVALGRTVTFQCEATGNPQPAIFWRREGS 353
Query: 762 TSAKQSDENGEAAYDLPAEDWIVANKDLIDKT-KFTITGLPTDAKIFVRVKAVNAAGASE 820
+N +Y P +++ + +T TIT + + + +N AG+
Sbjct: 354 -------QNLLFSYQPPQS----SSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSII 402
Query: 821 PKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI 880
K Y + V PP IR + QT V L G P P + W+KDG +
Sbjct: 403 TKAYLEVTDVIADRPPPVIR-QGPVNQTVA--VDGTFVLSCVATGSPVPTILWRKDGVLV 459
Query: 881 DKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIID--------RP 932
I+ E + ++ IR A+ +G+Y T S I++ + RP
Sbjct: 460 STQDSRIKQLE-NGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRP 518
Query: 933 GPPQIV-------KIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKS-MEWFTVIEH 984
P ++ ++ DV V L+W P + G A T Y I+ S W TV E+
Sbjct: 519 TDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSG-ATPTSYIIEAFSHASGSSWQTVAEN 577
Query: 985 YHRTSATITELVIGNEYYFRVFSENMCGLSEDATMT 1020
++ I L Y F V + N G+S+ + ++
Sbjct: 578 VKTETSAIKGLKPNAIYLFLVRAANAYGISDPSQIS 613
Score = 56.2 bits (134), Expect = 2e-07
Identities = 79/308 (25%), Positives = 123/308 (39%), Gaps = 66/308 (21%)
Query: 853 VGE-AVNLVIPFQGKPRPELTWKKDGAEID--KNQINIRNSETDTIIFIRKAERSHSGKY 909
VGE AV P +G P P ++WKKDG+ +D +I IR + + I +S +GKY
Sbjct: 144 VGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGK----LMITYTRKSDAGKY 199
Query: 910 DLQVKVDKFVETAS--IDIQIIDRPG----PPQI-VKIED-------VWGENV-ALTWTP 954
+ V + E S ++ +++RP P + V ++D G+ V + W
Sbjct: 200 -VCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWR- 257
Query: 955 PKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLS 1014
KDDG + Y I+ +H + I ++ G+ + +ENM G +
Sbjct: 258 -KDDGELPKSRYEIRD------------DH----TLKIRKVTAGDMGSYTCVAENMVGKA 300
Query: 1015 E-DATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGN 1073
E AT+T + SE P F + G T C GN
Sbjct: 301 EASATLTVQVG-------------------SEPPHFVVKPRDQVVALGRTVTFQCEATGN 341
Query: 1074 PKPKITWMK----NKVAIVDDPR-YRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTV 1128
P+P I W + N + P+ FS L I D G Y C+ +N G++
Sbjct: 342 PQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSI 401
Query: 1129 EIECKLEV 1136
+ LEV
Sbjct: 402 ITKAYLEV 409
Score = 53.5 bits (127), Expect = 1e-06
Identities = 84/348 (24%), Positives = 134/348 (38%), Gaps = 46/348 (13%)
Query: 802 TDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVI 861
+DA +V V N G E + +L + P ++ P +L T V ++
Sbjct: 194 SDAGKYVCV-GTNMVGERESEVAELTVLER----PSFVKRPSNLAVT----VDDSAEFKC 244
Query: 862 PFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVK--VDKFV 919
+G P P + W+KD E+ K++ IR+ T + IRK G Y + V K
Sbjct: 245 EARGDPVPTVRWRKDDGELPKSRYEIRDDHT---LKIRKVTAGDMGSYTCVAENMVGKAE 301
Query: 920 ETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPP---KDDGNAAITGYTIQKADKKSM 976
+A++ +Q+ P P +VK D + VAL T + GN + ++ + +
Sbjct: 302 ASATLTVQVGSEP-PHFVVKPRD---QVVALGRTVTFQCEATGNPQPAIFWRREGSQNLL 357
Query: 977 EWFTVIEHYHRTSA------TITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDG 1030
+ + R S TIT + + Y+ + N+ G + + VIA
Sbjct: 358 FSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIAD-- 415
Query: 1031 KIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAI-VD 1089
P+ Q VN L+C G+P P I W K+ V +
Sbjct: 416 -------------RPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQ 462
Query: 1090 DPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1137
D R + N GV L+IR D G Y C A G +EV+
Sbjct: 463 DSRIKQLEN-GV--LQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQ 507
Score = 51.2 bits (121), Expect = 5e-06
Identities = 72/322 (22%), Positives = 123/322 (38%), Gaps = 58/322 (18%)
Query: 836 PPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSE---- 891
PP RI H + + GE L +G+P P + W K G ++ ++ + R+
Sbjct: 28 PP--RIVEHPSDLIVSK-GEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLP 84
Query: 892 TDTIIFIR----KAERSHSGKYDLQVKV---DKFVETASIDIQIID---RPGPPQIVKIE 941
+ ++ F+R + R G Y + + AS+++ I+ R P ++
Sbjct: 85 SGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAV 144
Query: 942 DVWGENVALTWTPPKDDGNAAIT----GYTIQKADKK-SMEWFTVIEHYHRTSATITELV 996
GE + PP+ I+ G + D++ ++ ++ Y R S +
Sbjct: 145 ---GEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVC 201
Query: 997 IGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNT 1056
+G NM G +ES V + E P F + N
Sbjct: 202 VGT---------NMVG-------ERESEVA-------------ELTVLERPSFVKRPSNL 232
Query: 1057 YAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGT 1116
+A C RG+P P + W K+ + RY + + TL+IRK + D G+
Sbjct: 233 AVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKS-RYEIRDDH---TLKIRKVTAGDMGS 288
Query: 1117 YCCKAVNDLGTVEIECKLEVKV 1138
Y C A N +G E L V+V
Sbjct: 289 YTCVAENMVGKAEASATLTVQV 310
Score = 42.7 bits (99), Expect = 0.002
Identities = 34/88 (38%), Positives = 40/88 (45%), Gaps = 10/88 (11%)
Query: 1061 GYNATLNCSVRGNPKPKITWMKNKVAI---VDDPR-YRMFSNQG----VCTLEIRKPSPY 1112
G ATLNC G P P I W K + DDPR +RM G + + RK P
Sbjct: 43 GEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRP- 101
Query: 1113 DGGTYCCKAVNDLG-TVEIECKLEVKVI 1139
D G Y C A N LG V LEV ++
Sbjct: 102 DEGVYVCVARNYLGEAVSHNASLEVAIL 129
>gi|239748173 PREDICTED: similar to roundabout 1 isoform 1 [Homo
sapiens]
Length = 1562
Score = 102 bits (255), Expect = 2e-21
Identities = 125/478 (26%), Positives = 180/478 (37%), Gaps = 66/478 (13%)
Query: 279 PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGD------EKCS 332
P+ + W K+G + + I G I + D+ YV G E
Sbjct: 159 PEPTISWKKDGSPLDDKDERITIRGGKLMITYTRK----SDAGKYVCVGTNMVGERESEV 214
Query: 333 TELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDA-NVKWFKNGEEIIPGPKSRYRI 391
EL V E P V K+ + + E +CE D V+W K+ E+ PKSRY I
Sbjct: 215 AELTVLERPSFV-KRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGEL---PKSRYEI 270
Query: 392 RVEGKKHILIIEGATKADAAEYSV----MTTGGQSSAKLSVDL--KPLKILTPLTDQTVN 445
R + H L I T D Y+ M ++SA L+V + +P + DQ V
Sbjct: 271 RDD---HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEPPHFVVKPRDQVVA 327
Query: 446 LGKEICLKCEISENIPGK--WTKNGL--------PVQESDRLKVVHKGRIHKLVIANALT 495
LG+ + +CE + N W + G P Q S R V G L I N
Sbjct: 328 LGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTG---DLTITNVQR 384
Query: 496 EDEGDYVFAP--DAYNVTLPAKVHVID-----PPKIILDGLDADNTVTVIAGNKLRLEIP 548
D G Y+ A ++ A + V D PP +I G TV L
Sbjct: 385 SDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQG---PVNQTVAVDGTFVLSCV 441
Query: 549 ISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEA 608
+G P P +W + + RI+ ++ L I A+ D+G Y +GEA
Sbjct: 442 ATGSPVPTILWRKDGVLVSTQDSRIKQL---ENGVLQIRYAKLGDTGRYTCIASTPSGEA 498
Query: 609 HASIKVKVVDF---------------PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILG 653
S ++V +F P P P VT+V + ++W+P G +P
Sbjct: 499 TWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATP-TS 557
Query: 654 YFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRP 711
Y IE S + + K T K + Y + A NA GIS PS S P
Sbjct: 558 YIIEAFSHASGSSWQTVAENVKTETSAIKGLKPNAIYLFLVRAANAYGISDPSQISDP 615
Score = 72.4 bits (176), Expect = 2e-12
Identities = 182/788 (23%), Positives = 289/788 (36%), Gaps = 130/788 (16%)
Query: 350 DTTAYCGERVELECEV--SEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATK 407
D GE +EC+ + + W K+G P RI + G K L+I K
Sbjct: 139 DVMVAVGEPAVMECQPPRGHPEPTISWKKDGS---PLDDKDERITIRGGK--LMITYTRK 193
Query: 408 ADAAEYSVMTT---GGQSS--AKLSVDLKPLKILTPLTDQTVNLGKEICLKCEI-SENIP 461
+DA +Y + T G + S A+L+V +P + P ++ V + KCE + +P
Sbjct: 194 SDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRP-SNLAVTVDDSAEFKCEARGDPVP 252
Query: 462 G-KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAY------NVTLPA 514
+W K+ + +S R ++ H L I D G Y + + TL
Sbjct: 253 TVRWRKDDGELPKS-RYEIRDD---HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV 308
Query: 515 KVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIR 574
+V +PP ++ D V G + + +G P P W R EGS +
Sbjct: 309 QVGS-EPPHFVVKPRDQ----VVALGRTVTFQCEATGNPQPAIFWRR------EGSQNLL 357
Query: 575 TESYPDSST----------LVIDIAERDDSGVYHINLKNEAG----EAHASIKVKVVDFP 620
P S+ L I +R D G Y N AG +A+ + + D P
Sbjct: 358 FSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRP 417
Query: 621 DP-----PVAPTVTEVGDDW--CIMNWEPPA---YDGGSPILGYFIERKKKQSSRWMRLN 670
P PV TV G C+ P + ++ R K+ + +++
Sbjct: 418 PPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIR 477
Query: 671 FDLCKET------TFEPKKMIEGVAY-EVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTL 723
+ +T P AY EV+ F V P P RP P + S P+
Sbjct: 478 YAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGV-------PVQPPRPTDPNLIPSAPSK 530
Query: 724 LTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWI 783
V V+ TVT+ W+P + GA Y++E S S+ W
Sbjct: 531 PEVTDVSRNTVTLSWQPNLNSGATP-TSYIIEAFSHASGSS-----------------WQ 572
Query: 784 VANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPR 843
+++ +T I GL +A V+A NA G S+P S P+ ++++ P +
Sbjct: 573 TVAENVKTETS-AIKGLKPNAIYLFLVRAANAYGISDPSQISDPVKTQDVL-PTSQGVDH 630
Query: 844 HLKQTYIRRVGEAV-NLVIP-FQGKPRPELTWKKD-------GAEIDKNQINIRNSETDT 894
Q R +G AV +L P E+ W D G +I + E+D
Sbjct: 631 KQVQ---RELGNAVLHLHNPTVLSSSSIEVHWTVDQQSQYIQGYKILYRPSGANHGESDW 687
Query: 895 IIF-IRKAERSHSGKYDLQVKVDK-------FVETASIDIQI------IDRP-GPPQIVK 939
++F +R ++ DL+ V+ F E D +I + P PPQ V
Sbjct: 688 LVFEVRTPAKNSVVIPDLRKGVNYEIKARPFFNEFQGADSEIKFAKTLEEAPSAPPQGVT 747
Query: 940 I--EDVWGENVALTWTPPKDD-GNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELV 996
+ D G + ++W PP +D N + Y + ++ S I LV
Sbjct: 748 VSKNDGNGTAILVSWQPPPEDTQNGMVQEYKVWCLGNETRYHINKTVDGSTFSVVIPFLV 807
Query: 997 IGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNT 1056
G Y V + G + + E I D + NPV + S A + +
Sbjct: 808 PGIRYSVEVAASTGAG----SGVKSEPQFIQLDA--HGNPVSPEDQVSLAQQISDVVKQP 861
Query: 1057 YAIAGYNA 1064
IAG A
Sbjct: 862 AFIAGIGA 869
Score = 62.8 bits (151), Expect = 2e-09
Identities = 143/636 (22%), Positives = 238/636 (37%), Gaps = 77/636 (12%)
Query: 422 SSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPG---KWTKNGLPVQ------ 472
S ++L + P +I+ +D V+ G+ L C+ +E P +W K G V+
Sbjct: 18 SGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCK-AEGRPTPTIEWYKGGERVETDKDDP 76
Query: 473 ESDRLKVVHKGRIHKLVIANALTE--DEGDYVFAPDAYNVTLPAKVHVIDPPKIIL--DG 528
S R+ ++ G + L I + DEG YV A N A H IL D
Sbjct: 77 RSHRM-LLPSGSLFFLRIVHGRKSRPDEGVYVCV--ARNYLGEAVSHNASLEVAILRDDF 133
Query: 529 LDADNTVTVIAGNKLRLEI-PISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVID 587
+ V V G +E P G P P W + + + RI L+I
Sbjct: 134 RQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRG----GKLMIT 189
Query: 588 IAERDDSGVYHINLKNEAGEAHASI-KVKVVDFPD-----PPVAPTVTEVGDDWCIMNWE 641
+ D+G Y N GE + + ++ V++ P +A TV + + C +
Sbjct: 190 YTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGD 249
Query: 642 PPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIG 701
P R +K + +++ + T + +K+ G A N +G
Sbjct: 250 PVP-----------TVRWRKDDGELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVG 298
Query: 702 ISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGS 761
++ S + + V S P V D V + A G + + EGS
Sbjct: 299 KAEASAT----LTVQVGSEPPHFVVKP-RDQVVALGRTVTFQCEATGNPQPAIFWRREGS 353
Query: 762 TSAKQSDENGEAAYDLPAEDWIVANKDLIDKT-KFTITGLPTDAKIFVRVKAVNAAGASE 820
+N +Y P +++ + +T TIT + + + +N AG+
Sbjct: 354 -------QNLLFSYQPPQS----SSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSII 402
Query: 821 PKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI 880
K Y + V PP IR + QT V L G P P + W+KDG +
Sbjct: 403 TKAYLEVTDVIADRPPPVIR-QGPVNQTVA--VDGTFVLSCVATGSPVPTILWRKDGVLV 459
Query: 881 DKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIID--------RP 932
I+ E + ++ IR A+ +G+Y T S I++ + RP
Sbjct: 460 STQDSRIKQLE-NGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRP 518
Query: 933 GPPQIV-------KIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKS-MEWFTVIEH 984
P ++ ++ DV V L+W P + G A T Y I+ S W TV E+
Sbjct: 519 TDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSG-ATPTSYIIEAFSHASGSSWQTVAEN 577
Query: 985 YHRTSATITELVIGNEYYFRVFSENMCGLSEDATMT 1020
++ I L Y F V + N G+S+ + ++
Sbjct: 578 VKTETSAIKGLKPNAIYLFLVRAANAYGISDPSQIS 613
Score = 56.2 bits (134), Expect = 2e-07
Identities = 79/308 (25%), Positives = 123/308 (39%), Gaps = 66/308 (21%)
Query: 853 VGE-AVNLVIPFQGKPRPELTWKKDGAEID--KNQINIRNSETDTIIFIRKAERSHSGKY 909
VGE AV P +G P P ++WKKDG+ +D +I IR + + I +S +GKY
Sbjct: 144 VGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGK----LMITYTRKSDAGKY 199
Query: 910 DLQVKVDKFVETAS--IDIQIIDRPG----PPQI-VKIED-------VWGENV-ALTWTP 954
+ V + E S ++ +++RP P + V ++D G+ V + W
Sbjct: 200 -VCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWR- 257
Query: 955 PKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLS 1014
KDDG + Y I+ +H + I ++ G+ + +ENM G +
Sbjct: 258 -KDDGELPKSRYEIRD------------DH----TLKIRKVTAGDMGSYTCVAENMVGKA 300
Query: 1015 E-DATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGN 1073
E AT+T + SE P F + G T C GN
Sbjct: 301 EASATLTVQVG-------------------SEPPHFVVKPRDQVVALGRTVTFQCEATGN 341
Query: 1074 PKPKITWMK----NKVAIVDDPR-YRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTV 1128
P+P I W + N + P+ FS L I D G Y C+ +N G++
Sbjct: 342 PQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSI 401
Query: 1129 EIECKLEV 1136
+ LEV
Sbjct: 402 ITKAYLEV 409
Score = 53.5 bits (127), Expect = 1e-06
Identities = 84/348 (24%), Positives = 134/348 (38%), Gaps = 46/348 (13%)
Query: 802 TDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVI 861
+DA +V V N G E + +L + P ++ P +L T V ++
Sbjct: 194 SDAGKYVCV-GTNMVGERESEVAELTVLER----PSFVKRPSNLAVT----VDDSAEFKC 244
Query: 862 PFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVK--VDKFV 919
+G P P + W+KD E+ K++ IR+ T + IRK G Y + V K
Sbjct: 245 EARGDPVPTVRWRKDDGELPKSRYEIRDDHT---LKIRKVTAGDMGSYTCVAENMVGKAE 301
Query: 920 ETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPP---KDDGNAAITGYTIQKADKKSM 976
+A++ +Q+ P P +VK D + VAL T + GN + ++ + +
Sbjct: 302 ASATLTVQVGSEP-PHFVVKPRD---QVVALGRTVTFQCEATGNPQPAIFWRREGSQNLL 357
Query: 977 EWFTVIEHYHRTSA------TITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDG 1030
+ + R S TIT + + Y+ + N+ G + + VIA
Sbjct: 358 FSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIAD-- 415
Query: 1031 KIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAI-VD 1089
P+ Q VN L+C G+P P I W K+ V +
Sbjct: 416 -------------RPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQ 462
Query: 1090 DPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1137
D R + N GV L+IR D G Y C A G +EV+
Sbjct: 463 DSRIKQLEN-GV--LQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQ 507
Score = 51.2 bits (121), Expect = 5e-06
Identities = 72/322 (22%), Positives = 123/322 (38%), Gaps = 58/322 (18%)
Query: 836 PPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSE---- 891
PP RI H + + GE L +G+P P + W K G ++ ++ + R+
Sbjct: 28 PP--RIVEHPSDLIVSK-GEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLP 84
Query: 892 TDTIIFIR----KAERSHSGKYDLQVKV---DKFVETASIDIQIID---RPGPPQIVKIE 941
+ ++ F+R + R G Y + + AS+++ I+ R P ++
Sbjct: 85 SGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAV 144
Query: 942 DVWGENVALTWTPPKDDGNAAIT----GYTIQKADKK-SMEWFTVIEHYHRTSATITELV 996
GE + PP+ I+ G + D++ ++ ++ Y R S +
Sbjct: 145 ---GEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVC 201
Query: 997 IGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNT 1056
+G NM G +ES V + E P F + N
Sbjct: 202 VGT---------NMVG-------ERESEVA-------------ELTVLERPSFVKRPSNL 232
Query: 1057 YAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGT 1116
+A C RG+P P + W K+ + RY + + TL+IRK + D G+
Sbjct: 233 AVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKS-RYEIRDDH---TLKIRKVTAGDMGS 288
Query: 1117 YCCKAVNDLGTVEIECKLEVKV 1138
Y C A N +G E L V+V
Sbjct: 289 YTCVAENMVGKAEASATLTVQV 310
Score = 42.7 bits (99), Expect = 0.002
Identities = 34/88 (38%), Positives = 40/88 (45%), Gaps = 10/88 (11%)
Query: 1061 GYNATLNCSVRGNPKPKITWMKNKVAI---VDDPR-YRMFSNQG----VCTLEIRKPSPY 1112
G ATLNC G P P I W K + DDPR +RM G + + RK P
Sbjct: 43 GEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRP- 101
Query: 1113 DGGTYCCKAVNDLG-TVEIECKLEVKVI 1139
D G Y C A N LG V LEV ++
Sbjct: 102 DEGVYVCVARNYLGEAVSHNASLEVAIL 129
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.134 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 48,398,357
Number of Sequences: 37866
Number of extensions: 2395020
Number of successful extensions: 18781
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 171
Number of HSP's successfully gapped in prelim test: 247
Number of HSP's that attempted gapping in prelim test: 9345
Number of HSP's gapped (non-prelim): 4634
length of query: 1141
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1028
effective length of database: 13,968,660
effective search space: 14359782480
effective search space used: 14359782480
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.