Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 13236553
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13236553 nucleolar protein 12 [Homo sapiens]
(213 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13236553 nucleolar protein 12 [Homo sapiens] 420 e-118
gi|148746195 trichohyalin [Homo sapiens] 45 6e-05
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 41 7e-04
gi|22758136 MAP7 domain containing 2 [Homo sapiens] 41 9e-04
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 40 0.001
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 40 0.001
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 40 0.001
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 40 0.001
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 40 0.001
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 40 0.001
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 40 0.001
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 40 0.001
gi|32967605 bromodomain adjacent to zinc finger domain, 1A isofo... 40 0.001
gi|32967603 bromodomain adjacent to zinc finger domain, 1A isofo... 40 0.001
gi|194578896 golgi autoantigen, golgin subfamily a, 8E [Homo sap... 40 0.001
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 40 0.001
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 40 0.001
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 39 0.003
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 39 0.003
gi|115648142 centrosomal protein 164kDa [Homo sapiens] 39 0.003
gi|150378449 X-ray radiation resistance associated 1 [Homo sapiens] 39 0.003
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 39 0.003
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 39 0.003
gi|149363664 septin 8 isoform d [Homo sapiens] 39 0.004
gi|149363638 septin 8 isoform c [Homo sapiens] 39 0.004
gi|149363689 septin 8 isoform a [Homo sapiens] 39 0.004
gi|149363661 septin 8 isoform b [Homo sapiens] 39 0.004
gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo... 39 0.004
gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo... 39 0.004
gi|4506467 radixin [Homo sapiens] 38 0.006
>gi|13236553 nucleolar protein 12 [Homo sapiens]
Length = 213
Score = 420 bits (1079), Expect = e-118
Identities = 213/213 (100%), Positives = 213/213 (100%)
Query: 1 MGRNKKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKL 60
MGRNKKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKL
Sbjct: 1 MGRNKKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKL 60
Query: 61 REERHQEYLKMLAEREEALEEADELDRLVTAKTESVQYDHPNHTVTVTTISDLDLSGARL 120
REERHQEYLKMLAEREEALEEADELDRLVTAKTESVQYDHPNHTVTVTTISDLDLSGARL
Sbjct: 61 REERHQEYLKMLAEREEALEEADELDRLVTAKTESVQYDHPNHTVTVTTISDLDLSGARL 120
Query: 121 LGLTPPEGGAGDRSEEEASSTEKPTKALPRKSRDPLLSQRISSLTASLHAHSRKKVKRKH 180
LGLTPPEGGAGDRSEEEASSTEKPTKALPRKSRDPLLSQRISSLTASLHAHSRKKVKRKH
Sbjct: 121 LGLTPPEGGAGDRSEEEASSTEKPTKALPRKSRDPLLSQRISSLTASLHAHSRKKVKRKH 180
Query: 181 PRRAQDSKKPPRAPRTSKAQRRRLTGKARHSGE 213
PRRAQDSKKPPRAPRTSKAQRRRLTGKARHSGE
Sbjct: 181 PRRAQDSKKPPRAPRTSKAQRRRLTGKARHSGE 213
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 44.7 bits (104), Expect = 6e-05
Identities = 56/222 (25%), Positives = 96/222 (43%), Gaps = 31/222 (13%)
Query: 3 RNKKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLR- 61
R ++++R R L ++E+RRE L ++ E K+ E +QRLK EQ + R
Sbjct: 521 RQEEEERLQQRLRSEQQLRREQEERREQLL----KREEEKRLEQERREQRLKREQEERRD 576
Query: 62 ------EERHQEYLKMLAEREEALEE---ADELDRL--VTAKTESVQYDHPNHTVTVTTI 110
EER Q+ LK E+EE LE+ +E++RL + + ++ + P +
Sbjct: 577 QLLKREEERRQQRLKR--EQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLL 634
Query: 111 SDLDLSGARLLGLTPPEGGAGDRSEEEASSTEKPTKALPRKSRDPLLSQRISSLTASLHA 170
+ R L + +R E+ E+ + R R+ +R L
Sbjct: 635 KSEEQEERRQQQLRREQ---QERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQE 691
Query: 171 HSRKKVKRKHPR---------RAQDSKKPPRAPRTSKAQRRR 203
+R+++K + P+ A+ SK R PR + QRRR
Sbjct: 692 QARERIKSRIPKWQWQLESEADARQSKVYSR-PRKQEGQRRR 732
Score = 39.3 bits (90), Expect = 0.003
Identities = 49/217 (22%), Positives = 88/217 (40%), Gaps = 15/217 (6%)
Query: 3 RNKKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEE------ 56
R ++ KRD ++ R L +EE+RRE +R+ + ++ E +QRLK +
Sbjct: 472 RKQQLKRDQEEERRERWLKLEEEERREQQ---ERREQQLRREQEERREQRLKRQEEEERL 528
Query: 57 QRKLREERHQEYLKMLAEREEALEEADELDRLVTAKTESVQYDHPNHTVTVTTISDLDLS 116
Q++LR E Q+ + ER E L + +E RL + E + + +
Sbjct: 529 QQRLRSE--QQLRREQEERREQLLKREEEKRLEQERREQ-RLKREQEERRDQLLKREEER 585
Query: 117 GARLLGLTPPEGGAGDRSEEEASSTEKPTKALPRKSRDPLLSQRISSLTASLHAHSRKKV 176
+ L E EE E+ + R R+ +R L L + +++
Sbjct: 586 RQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQL---LKSEEQEER 642
Query: 177 KRKHPRRAQDSKKPPRAPRTSKAQRRRLTGKARHSGE 213
+++ RR Q ++ R R + +R K H E
Sbjct: 643 RQQQLRREQQERREQRLKREEEEERLEQRLKREHEEE 679
Score = 37.4 bits (85), Expect = 0.010
Identities = 28/84 (33%), Positives = 41/84 (48%), Gaps = 3/84 (3%)
Query: 3 RNKKKKRDGDDRRPRLVLSFD-EEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLR 61
+ + K+RD + + +L + EEKRR T R+ E+ EE R +E RK R
Sbjct: 1304 QKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFR 1363
Query: 62 EE--RHQEYLKMLAEREEALEEAD 83
EE RHQE + E E+ L +
Sbjct: 1364 EEELRHQEQGRKFLEEEQRLRRQE 1387
Score = 35.0 bits (79), Expect = 0.047
Identities = 25/89 (28%), Positives = 47/89 (52%), Gaps = 7/89 (7%)
Query: 3 RNKKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLRE 62
+ ++++R+ R + +E+ RE ++++ER+ EE++Q EE++ LRE
Sbjct: 1100 KRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQ---EEEQLLRE 1156
Query: 63 E----RHQEYLKMLAEREEALEEADELDR 87
E R QE + E EE +E ++L R
Sbjct: 1157 EPEKRRRQELERQYREEEELQQEEEQLLR 1185
Score = 35.0 bits (79), Expect = 0.047
Identities = 24/86 (27%), Positives = 47/86 (54%), Gaps = 8/86 (9%)
Query: 5 KKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLREER 64
+++ R DR+ R +EE++ K + E ++ +E +++ EE+++LR+ER
Sbjct: 1405 EQQLRQDRDRKFR-----EEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQER 1459
Query: 65 HQEYL---KMLAEREEALEEADELDR 87
H+++ ++L EREE E DR
Sbjct: 1460 HRKFREEEQLLQEREEQQLHRQERDR 1485
Score = 33.5 bits (75), Expect = 0.14
Identities = 21/82 (25%), Positives = 44/82 (53%), Gaps = 4/82 (4%)
Query: 5 KKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQ--RKLRE 62
+K++ + P+ EE+ E L ++++ R++ E+ +QRL+ EQ R+ +E
Sbjct: 254 RKEEEKLQEEEPQRQRELQEEE--EQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQE 311
Query: 63 ERHQEYLKMLAEREEALEEADE 84
E +E + E++E E+ +E
Sbjct: 312 EERREQQEERREQQERREQQEE 333
Score = 33.1 bits (74), Expect = 0.18
Identities = 26/90 (28%), Positives = 46/90 (51%), Gaps = 15/90 (16%)
Query: 3 RNKKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQR------LKEE 56
R +K++R DR+ R +E+ + L +R+ +K EE++ + L+EE
Sbjct: 1325 REEKRRRQETDRKFREEEQLLQEREEQPL----RRQERDRKFREEELRHQEQGRKFLEEE 1380
Query: 57 QRKLREERHQEYLK-----MLAEREEALEE 81
QR R+ER +++LK ERE+ L +
Sbjct: 1381 QRLRRQERERKFLKEEQQLRCQEREQQLRQ 1410
Score = 32.7 bits (73), Expect = 0.24
Identities = 23/70 (32%), Positives = 37/70 (52%), Gaps = 7/70 (10%)
Query: 23 DEEKR-----REYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLREERHQEYLKMLAEREE 77
DEEKR +E L R+ E + E ++L+EE + R ++ QE + LAE EE
Sbjct: 96 DEEKRARCDGKESL--LQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEE 153
Query: 78 ALEEADELDR 87
E+ + L++
Sbjct: 154 QSEKQERLEQ 163
Score = 32.7 bits (73), Expect = 0.24
Identities = 22/100 (22%), Positives = 49/100 (49%), Gaps = 2/100 (2%)
Query: 3 RNKKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLRE 62
R ++ +R+ ++RR + + EE+RRE + + R++ E + R +++ R+ ++
Sbjct: 335 REQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQ 394
Query: 63 ERHQEYLK--MLAEREEALEEADELDRLVTAKTESVQYDH 100
R ++ L+ RE+ L +L R + E + H
Sbjct: 395 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERH 434
Score = 32.3 bits (72), Expect = 0.31
Identities = 41/208 (19%), Positives = 83/208 (39%), Gaps = 26/208 (12%)
Query: 3 RNKKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLRE 62
R ++ +R+ RR + + + +R + L + + R++ E +Q+ ++E+R+ R
Sbjct: 391 REQQLRREQQLRREQQLRREQQLRREQQL---RREQQLRREQEEERHEQKHEQERREQRL 447
Query: 63 ERHQEYLKMLAEREEALEEADELDRLVTAKTESVQYDHPNHTVTVTTISDLDLSGARLLG 122
+R QE + +REE E ++ R K + + R L
Sbjct: 448 KREQEERRDWLKREEETERHEQERRKQQLKRDQEEERR-----------------ERWLK 490
Query: 123 LTPPEGGAGDRSEEE---ASSTEKPTKALPRKSRDPLLSQRISS---LTASLHAHSRKKV 176
L E E+ E+ + L R+ + L QR+ S L + +
Sbjct: 491 LEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLL 550
Query: 177 KRKHPRRAQDSKKPPRAPRTSKAQRRRL 204
KR+ +R + ++ R R + +R +L
Sbjct: 551 KREEEKRLEQERREQRLKREQEERRDQL 578
Score = 32.3 bits (72), Expect = 0.31
Identities = 43/212 (20%), Positives = 86/212 (40%), Gaps = 4/212 (1%)
Query: 4 NKKKKRDGDDRRP-RLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEE-QRKLR 61
+++++R + RR + +EE++R T + K ++ + +++ Q +EE QR+ R
Sbjct: 859 DQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREER 918
Query: 62 EE-RHQEYLKMLAEREEALEEADELDRLVTAKTESVQYDHPNHTVTVTTISDLDLSGARL 120
E+ R QE + E E+ +E ++L R K + + + L G
Sbjct: 919 EKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEP 978
Query: 121 LGLTPPEGGAGDRSEEEASSTEKPTKALPRKSRDPLLSQRISSLTASLHAHSRKKVK-RK 179
E R EEE E+ R+ R +R L + ++ +
Sbjct: 979 EKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREER 1038
Query: 180 HPRRAQDSKKPPRAPRTSKAQRRRLTGKARHS 211
RR Q+ ++ R + + +L G+ R +
Sbjct: 1039 EKRRLQERERQYREEEELQQEEEQLLGEERET 1070
Score = 32.3 bits (72), Expect = 0.31
Identities = 26/91 (28%), Positives = 50/91 (54%), Gaps = 6/91 (6%)
Query: 3 RNKKKKRDGDDRRPRLVLSFDEEKRREYLTGFH---KRKVERKKAAIEEIKQRLKEEQ-- 57
R +++KR +R + +++ E L G +R+ ER+K EE + + +EEQ
Sbjct: 945 REEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLL 1004
Query: 58 RKLREE-RHQEYLKMLAEREEALEEADELDR 87
R+ RE+ R QE+ + +++E +E ++L R
Sbjct: 1005 REEREKRRRQEWERQYRKKDELQQEEEQLLR 1035
Score = 32.3 bits (72), Expect = 0.31
Identities = 22/85 (25%), Positives = 42/85 (49%), Gaps = 15/85 (17%)
Query: 3 RNKKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLRE 62
R +++ + +L+ E++RR+ L +R+ ++ +E +Q L+EEQ K R+
Sbjct: 1138 RQYREEEEVQQEEEQLLREEPEKRRRQEL----ERQYREEEELQQEEEQLLREEQEKRRQ 1193
Query: 63 ERHQEYLKMLAEREEALEEADELDR 87
ER ++Y E +EL R
Sbjct: 1194 ERERQY-----------REEEELQR 1207
Score = 32.0 bits (71), Expect = 0.40
Identities = 25/87 (28%), Positives = 43/87 (49%), Gaps = 5/87 (5%)
Query: 3 RNKKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQR--LKEEQRKL 60
R K ++ RR R F EE+ +E+ + E +K EE +++ L+EE+ +L
Sbjct: 219 RRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQL 278
Query: 61 REERHQEYLKMLAEREEALEEADELDR 87
R+ QE + ER+E ++ L R
Sbjct: 279 RKLERQE---LRRERQEEEQQQQRLRR 302
Score = 31.6 bits (70), Expect = 0.52
Identities = 21/85 (24%), Positives = 47/85 (55%), Gaps = 9/85 (10%)
Query: 3 RNKKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLRE 62
R ++++R+ + R L ++E+RRE + + E+++ E+ +R +EE+R+ ++
Sbjct: 322 REQQERREQQEERREQQLRREQEERRE-----QQLRREQEEERREQQLRREQEEERREQQ 376
Query: 63 ERHQEYLKMLAEREEALEEADELDR 87
R ++ L+ RE+ L +L R
Sbjct: 377 LRREQQLR----REQQLRREQQLRR 397
Score = 31.6 bits (70), Expect = 0.52
Identities = 46/205 (22%), Positives = 88/205 (42%), Gaps = 24/205 (11%)
Query: 5 KKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLREER 64
+K++R +R+ R +E+ + KR+ ER++ EE + + ++ +++ R+E
Sbjct: 1159 EKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDED 1218
Query: 65 HQEYLKMLAEREEALEEADELDRLVTAKTESVQYDHPNHTVTVTTISDLDLSGARLLGLT 124
+ LK E E+ E A +++ E+ Q+ + S DL LLG
Sbjct: 1219 QRSDLKWQWEPEK--ENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQ--HLLG-- 1272
Query: 125 PPEGGAGDRSEEEASSTEKPTKALPRKSRDPLLSQRISSLTASLHAHSRKKVKRKHPRRA 184
E DR E+E ++ + P + + L +K+ KR+ R++
Sbjct: 1273 --EQQERDR-EQERRRWQQRDRHFPEEEQ--------------LEREEQKEAKRR-DRKS 1314
Query: 185 QDSKKPPRAPRTSKAQRRRLTGKAR 209
Q+ K+ R R K +R+ K R
Sbjct: 1315 QEEKQLLREEREEKRRRQETDRKFR 1339
Score = 31.6 bits (70), Expect = 0.52
Identities = 25/88 (28%), Positives = 39/88 (44%), Gaps = 6/88 (6%)
Query: 6 KKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLR---- 61
++ RD R LS E R+ R+ ER++ +EE +Q +E RK R
Sbjct: 1409 RQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQ 1468
Query: 62 --EERHQEYLKMLAEREEALEEADELDR 87
+ER ++ L + LEE +L R
Sbjct: 1469 LLQEREEQQLHRQERDRKFLEEEQQLRR 1496
Score = 31.6 bits (70), Expect = 0.52
Identities = 24/79 (30%), Positives = 41/79 (51%), Gaps = 5/79 (6%)
Query: 14 RRPRLVLSF-DEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKL----REERHQEY 68
RR L F +EE+ R+ R+ ER + +EE + R + E+++L R+ + +E
Sbjct: 1717 RRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREE 1776
Query: 69 LKMLAEREEALEEADELDR 87
++ EREE + E DR
Sbjct: 1777 EQLRQEREEQQLRSQESDR 1795
Score = 31.2 bits (69), Expect = 0.68
Identities = 22/85 (25%), Positives = 42/85 (49%), Gaps = 4/85 (4%)
Query: 7 KKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLREE--- 63
++R +R+ R +E+ + KR+ + ++ E ++ +EE++ LREE
Sbjct: 1071 RRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREK 1130
Query: 64 -RHQEYLKMLAEREEALEEADELDR 87
R QE + E EE +E ++L R
Sbjct: 1131 RRRQELERQYREEEEVQQEEEQLLR 1155
Score = 30.4 bits (67), Expect = 1.2
Identities = 21/87 (24%), Positives = 44/87 (50%), Gaps = 4/87 (4%)
Query: 5 KKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLREE- 63
+K++R +R+ R +E+ + KR+++ ++ E ++ +EE++ L EE
Sbjct: 1009 EKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEER 1068
Query: 64 ---RHQEYLKMLAEREEALEEADELDR 87
R QE + + EE +E ++L R
Sbjct: 1069 ETRRRQELERQYRKEEELQQEEEQLLR 1095
Score = 30.0 bits (66), Expect = 1.5
Identities = 37/206 (17%), Positives = 84/206 (40%), Gaps = 20/206 (9%)
Query: 6 KKKRDGDDRRPRLVLSFDEEKRRE---------YLTGFHKRKVERKKAAIEEIKQRLKEE 56
+++RD + R R EE+R E + T + + ++ + E++++ +EE
Sbjct: 166 RQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREE 225
Query: 57 QRKLREERHQEYLKMLAEREEALEEADELDRLVTAKTESVQYDHPNHTVTVTTISDLDLS 116
+++ R ER +EE +E + + ++ + E +Q + P +L
Sbjct: 226 KQQQRRERQDRVF-----QEEEEKEWRKRETVLRKEEEKLQEEEPQRQ------RELQEE 274
Query: 117 GARLLGLTPPEGGAGDRSEEEASSTEKPTKALPRKSRDPLLSQRISSLTASLHAHSRKKV 176
+L L E + EE+ + + L RK + Q+ +++
Sbjct: 275 EEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEER 334
Query: 177 KRKHPRRAQDSKKPPRAPRTSKAQRR 202
+ + RR Q+ ++ + R + +RR
Sbjct: 335 REQQLRREQEERREQQLRREQEEERR 360
Score = 30.0 bits (66), Expect = 1.5
Identities = 18/85 (21%), Positives = 45/85 (52%), Gaps = 4/85 (4%)
Query: 7 KKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEE----QRKLRE 62
+++ ++RR + ++++RRE ++++ R++ E + R ++E +++LR
Sbjct: 307 RRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRR 366
Query: 63 ERHQEYLKMLAEREEALEEADELDR 87
E+ +E + RE+ L +L R
Sbjct: 367 EQEEERREQQLRREQQLRREQQLRR 391
Score = 30.0 bits (66), Expect = 1.5
Identities = 24/85 (28%), Positives = 43/85 (50%), Gaps = 9/85 (10%)
Query: 6 KKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLREE-- 63
+++R DR+ R +E+ + L+ R+ +K +EE K R +E++RK E+
Sbjct: 1547 QQRRQDRDRKFREEEQLRQEREEQQLS----RQERDRKFRLEEQKVRRQEQERKFMEDEQ 1602
Query: 64 --RHQEYLKML-AEREEALEEADEL 85
R QE + L ER+ E ++L
Sbjct: 1603 QLRRQEGQQQLRQERDRKFREDEQL 1627
Score = 29.6 bits (65), Expect = 2.0
Identities = 22/87 (25%), Positives = 45/87 (51%), Gaps = 6/87 (6%)
Query: 3 RNKKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQ----- 57
R +++++ RR + + EE+RRE + + ER++ E +Q+L+ EQ
Sbjct: 290 RQEEEQQQQRLRREQQLRRKQEEERREQQEE-RREQQERREQQEERREQQLRREQEERRE 348
Query: 58 RKLREERHQEYLKMLAEREEALEEADE 84
++LR E+ +E + RE+ E ++
Sbjct: 349 QQLRREQEEERREQQLRREQEEERREQ 375
Score = 29.3 bits (64), Expect = 2.6
Identities = 18/75 (24%), Positives = 39/75 (52%)
Query: 3 RNKKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLRE 62
+ ++++ + R V +E+ RE ++++ER+ EE++Q ++ R+ +E
Sbjct: 1130 KRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQE 1189
Query: 63 ERHQEYLKMLAEREE 77
+R QE + E EE
Sbjct: 1190 KRRQERERQYREEEE 1204
Score = 28.9 bits (63), Expect = 3.4
Identities = 21/80 (26%), Positives = 41/80 (51%), Gaps = 6/80 (7%)
Query: 2 GRNKKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLR 61
G ++ +R DR+ R +EE++ K E ++ +E++++ +EE++ LR
Sbjct: 1679 GEEQQLRRQERDRKFR-----EEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQ-LR 1732
Query: 62 EERHQEYLKMLAEREEALEE 81
+E QE L+ + LEE
Sbjct: 1733 QETEQEQLRRQERYRKILEE 1752
Score = 28.9 bits (63), Expect = 3.4
Identities = 20/66 (30%), Positives = 38/66 (57%), Gaps = 3/66 (4%)
Query: 23 DEEKRREYLTGFHKRKVERK-KAAIEEIKQRLKEEQRKLREERHQEYL--KMLAEREEAL 79
+EE+ R+ R +R K EE + +L+E++++LR+ER ++Y + A +E++
Sbjct: 1799 EEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSR 1858
Query: 80 EEADEL 85
E EL
Sbjct: 1859 REEQEL 1864
Score = 27.7 bits (60), Expect = 7.6
Identities = 26/91 (28%), Positives = 47/91 (51%), Gaps = 13/91 (14%)
Query: 3 RNKKKKRDGDDRRPRLVLSFDEEKRREYLTGFHK-----RKVERKKAAIEEIKQRLKEEQ 57
R +++KR +R + + ++ E L G + +++ER+ EE++Q EE+
Sbjct: 1035 REEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQ---EEE 1091
Query: 58 RKLREE----RHQEYLKMLAEREEALEEADE 84
+ LREE R QE + E EE L++ +E
Sbjct: 1092 QLLREEPEKRRRQERERQCREEEE-LQQEEE 1121
Score = 27.7 bits (60), Expect = 7.6
Identities = 20/71 (28%), Positives = 34/71 (47%), Gaps = 12/71 (16%)
Query: 5 KKKKRDGDDRRPRLVLSFDEEKRR------------EYLTGFHKRKVERKKAAIEEIKQR 52
+ ++RDG R L +E+++R E K + E ++ EE ++R
Sbjct: 1813 RPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKR 1872
Query: 53 LKEEQRKLREE 63
+E +RKLREE
Sbjct: 1873 RQERERKLREE 1883
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 41.2 bits (95), Expect = 7e-04
Identities = 44/202 (21%), Positives = 74/202 (36%), Gaps = 39/202 (19%)
Query: 2 GRNKKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLR 61
G+ +++ +RR R + EK R+ G ++K ERKK E K+R +E++ K
Sbjct: 51 GKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE-RERKKRRREKENKEG 109
Query: 62 EERHQEYLKMLAEREEALEEADELDRLVTAKTESVQYDHPNHTVTVTTISDLDLSGARLL 121
EE+ + K ER +E E +R K E
Sbjct: 110 EEKEKRKKKEKKERGRTSKEGKERERKEERKRE--------------------------- 142
Query: 122 GLTPPEGGAGDRSEEEASSTEKPTKALPRKSRDPLLSQRISSLTASLHAHSRKKVKRKHP 181
+R E E E+ K RK R +++ RK+ K++
Sbjct: 143 ----------ERKERERKKEER-EKERERKERKKRERKQVGEKEEERKEKERKERKKRER 191
Query: 182 RRAQDSKKPPRAPRTSKAQRRR 203
R + K+ R R + + R+
Sbjct: 192 NRKERKKERERKERRERKKERK 213
Score = 40.0 bits (92), Expect = 0.001
Identities = 26/92 (28%), Positives = 48/92 (52%), Gaps = 3/92 (3%)
Query: 3 RNKKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLRE 62
R +K++R ++R+ R + EK RE ++K ERK+ +E +++ KE + + +
Sbjct: 133 RERKEERKREERKERERKKEEREKERERK---ERKKRERKQVGEKEEERKEKERKERKKR 189
Query: 63 ERHQEYLKMLAEREEALEEADELDRLVTAKTE 94
ER+++ K ER+E E E + K E
Sbjct: 190 ERNRKERKKERERKERRERKKERKKKEERKKE 221
Score = 31.6 bits (70), Expect = 0.52
Identities = 21/82 (25%), Positives = 41/82 (50%), Gaps = 3/82 (3%)
Query: 3 RNKKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLRE 62
+ +++K+ G+ R E K+RE K++ ERK+ + +++ KEE++K R+
Sbjct: 164 KKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQ 223
Query: 63 ERHQEYLKMLAEREEALEEADE 84
+ Q + E+E E E
Sbjct: 224 KDRQTNWR---EKERGKRERKE 242
Score = 30.8 bits (68), Expect = 0.89
Identities = 17/81 (20%), Positives = 42/81 (51%)
Query: 3 RNKKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLRE 62
R K+++R +R R + EE+R+E K++ +K +E +++ + E++K R+
Sbjct: 154 REKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERK 213
Query: 63 ERHQEYLKMLAEREEALEEAD 83
++ + + +R+ E +
Sbjct: 214 KKEERKKERQKDRQTNWREKE 234
Score = 28.5 bits (62), Expect = 4.4
Identities = 17/65 (26%), Positives = 36/65 (55%), Gaps = 11/65 (16%)
Query: 3 RNKKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLRE 62
RN+K+++ +R+ R E+++E K+K ERKK ++ + +E++R RE
Sbjct: 191 RNRKERKKERERKER------RERKKE-----RKKKEERKKERQKDRQTNWREKERGKRE 239
Query: 63 ERHQE 67
+ ++
Sbjct: 240 RKERK 244
>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
Length = 732
Score = 40.8 bits (94), Expect = 9e-04
Identities = 45/176 (25%), Positives = 83/176 (47%), Gaps = 24/176 (13%)
Query: 13 DRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLREERHQEYLKML 72
D R RL EE R + L ++ +E++K A + +++++E RKL E+R +E K
Sbjct: 52 DERQRLAKERREE-REKCLAAREQQILEKQKRARLQYEKQMEERWRKLEEQRQREDQKRA 110
Query: 73 A----EREEALEEADELDRLVTAKTESVQYDHPNHTVTVTTISDLDLSGARLLGLTPPEG 128
A +++ EE + L+ ++ E Q L+L G G
Sbjct: 111 AVEEKRKQKLREEEERLEAMMRRSLERTQ--------------QLELKKKYSWGAPLAIG 156
Query: 129 GAGDRSEEEASSTEKPTKALPRKSRDPLLSQRISSLTASLHAHSRKKVKRKHPRRA 184
G + ++ S++ T +LP K +P +++R+SS T ++ ++S +V PR A
Sbjct: 157 PGGHDACDKLSTS---TMSLP-KPTEPPMNKRLSSSTVAI-SYSPDRVFHVCPRLA 207
Score = 33.5 bits (75), Expect = 0.14
Identities = 28/75 (37%), Positives = 38/75 (50%), Gaps = 2/75 (2%)
Query: 14 RRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLREER-HQEYLKML 72
R+ RL +E++R E + E K+ A EE + RL+EE RK EER QE K
Sbjct: 409 RQARLQKEQEEQERVEKEEQDRLEREELKRKAEEE-RLRLEEEARKQEEERKRQEEEKKK 467
Query: 73 AEREEALEEADELDR 87
E EE + +E R
Sbjct: 468 QEGEEKRKAGEEAKR 482
Score = 31.6 bits (70), Expect = 0.52
Identities = 24/92 (26%), Positives = 46/92 (50%), Gaps = 19/92 (20%)
Query: 5 KKKKRDGDDRRP-----------RLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRL 53
+KKK++G+++R L+L +E+ ++ K +E++K A E +
Sbjct: 464 EKKKQEGEEKRKAGEEAKRKAEEELLLKEKQEQEKQ-----EKAMIEKQKEAAE---TKA 515
Query: 54 KEEQRKLREERHQEYLKMLAEREEALEEADEL 85
+E ++R ER Q L++ ER E + DE+
Sbjct: 516 REVAEQMRLEREQIMLQIEQERLERKKRIDEI 547
Score = 31.2 bits (69), Expect = 0.68
Identities = 23/76 (30%), Positives = 42/76 (55%), Gaps = 3/76 (3%)
Query: 8 KRDGDDRRPRLVLSF--DEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEE-QRKLREER 64
KR ++ R RL EE+R+ K++ E K+ A EE K++ +EE K ++E+
Sbjct: 437 KRKAEEERLRLEEEARKQEEERKRQEEEKKKQEGEEKRKAGEEAKRKAEEELLLKEKQEQ 496
Query: 65 HQEYLKMLAEREEALE 80
++ M+ +++EA E
Sbjct: 497 EKQEKAMIEKQKEAAE 512
Score = 30.8 bits (68), Expect = 0.89
Identities = 25/102 (24%), Positives = 46/102 (45%), Gaps = 14/102 (13%)
Query: 3 RNKKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLRE 62
R + + + + + R+ + RE L KRK E ++ +EE ++ +EE+++ E
Sbjct: 408 RRQARLQKEQEEQERVEKEEQDRLEREEL----KRKAEEERLRLEEEARKQEEERKRQEE 463
Query: 63 ERHQ----------EYLKMLAEREEALEEADELDRLVTAKTE 94
E+ + E K AE E L+E E ++ A E
Sbjct: 464 EKKKQEGEEKRKAGEEAKRKAEEELLLKEKQEQEKQEKAMIE 505
Score = 28.5 bits (62), Expect = 4.4
Identities = 27/96 (28%), Positives = 48/96 (50%), Gaps = 14/96 (14%)
Query: 3 RNKKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKV--ERKKAAIEEIKQRLKEEQRKL 60
R +++ R ++ R R +EEK+++ G KRK E K+ A EE+ + K+EQ K
Sbjct: 446 RLEEEARKQEEERKRQ----EEEKKKQ--EGEEKRKAGEEAKRKAEEELLLKEKQEQEK- 498
Query: 61 REERHQEYLKMLAEREEALEEADELDRLVTAKTESV 96
QE + ++E A +A E+ + + E +
Sbjct: 499 -----QEKAMIEKQKEAAETKAREVAEQMRLEREQI 529
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 40.4 bits (93), Expect = 0.001
Identities = 35/129 (27%), Positives = 60/129 (46%), Gaps = 9/129 (6%)
Query: 36 KRKVERKKAAIEEI-------KQRLKEEQRKLREERHQEYLKMLAEREEALEEADELDRL 88
+R +E++KA +E++ Q+L+EEQ++ +++ QE +++A EEA E +
Sbjct: 2506 ERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEG 2565
Query: 89 VTAKTESVQYDHPNHTVTVTTISDLDLSGARLLGLTPPEGGAG-DRSEEEASSTEKPTKA 147
V K E +Q +++ + L L + A SEE +S TK
Sbjct: 2566 VRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKT 2625
Query: 148 LPRKSRDPL 156
LP RD L
Sbjct: 2626 LP-NGRDAL 2633
Score = 40.4 bits (93), Expect = 0.001
Identities = 25/95 (26%), Positives = 57/95 (60%), Gaps = 6/95 (6%)
Query: 5 KKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLREE- 63
+++++ + R RLV S +E +RR++ + V RK+ +++++Q+ ++++ L EE
Sbjct: 2535 QRQQQQMEQERQRLVASMEEARRRQHEA---EEGVRRKQEELQQLEQQRRQQEELLAEEN 2591
Query: 64 -RHQEYLKMLAEREE-ALEEADELDRLVTAKTESV 96
R +E L++L E+ AL ++E+ A T+++
Sbjct: 2592 QRLREQLQLLEEQHRAALAHSEEVTASQVAATKTL 2626
Score = 35.0 bits (79), Expect = 0.047
Identities = 43/199 (21%), Positives = 84/199 (42%), Gaps = 19/199 (9%)
Query: 20 LSFDEEKRR-------EYLTGFHKRKVERKKAAIEEIKQRLK---EEQRKLREERHQEYL 69
L+ +EE+RR + + ++KAA+EE+ +RLK EE R+LRE QE
Sbjct: 1975 LAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEV-ERLKAKVEEARRLRERAEQESA 2033
Query: 70 KMLAEREEALEEADELDR-----LVTAKTESVQYDHPNHTVTVTTISDLDLSGARLLGLT 124
+ L +EA ++ + + V K + +Q + + + AR
Sbjct: 2034 RQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRG-EAEAARRAAEE 2092
Query: 125 PPEGGAGDRSEEEASSTEKPTKALPRKSRDPLLSQRISSLTASLHAHSRKKVKRKHPRRA 184
E A ++E EA+ + + + R + + + + RK+ +++ RRA
Sbjct: 2093 AEE--ARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRA 2150
Query: 185 QDSKKPPRAPRTSKAQRRR 203
Q + R + + A+ +
Sbjct: 2151 QAEQAALRQKQAADAEMEK 2169
Score = 28.5 bits (62), Expect = 4.4
Identities = 17/40 (42%), Positives = 26/40 (65%), Gaps = 1/40 (2%)
Query: 46 IEEIKQRLKEEQRKLREERHQEYLKMLAEREEALEEADEL 85
I E +R++EE+R L E++ E + LAE E ALE+ +L
Sbjct: 1337 ISETLRRMEEEER-LAEQQRAEERERLAEVEAALEKQRQL 1375
Score = 28.5 bits (62), Expect = 4.4
Identities = 49/202 (24%), Positives = 87/202 (43%), Gaps = 29/202 (14%)
Query: 4 NKKKKRDGDD---RRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQR--LKEEQR 58
N++ +R +D +R RL EE+ ++ +R + +KA+ E++++ L E+
Sbjct: 1863 NERLRRLAEDEAFQRRRL-----EEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTL 1917
Query: 59 KLREERHQEYLKMLAEREEALEEADELDRLVTAKTESVQYDHPNHTVTVTTISDLDLSGA 118
+ R + +E L + A E+A EL+ L + S N T+ + +L A
Sbjct: 1918 RQRRQVEEEILALKASFEKAAAGKAELE-LELGRIRS------NAEDTLRSKEQAELEAA 1970
Query: 119 RLLGLTPPEGGAGDRSEEEASSTEKPTKALPRKSRDPLLSQRISSLTASLHAHSRKKVKR 178
R L E +R EA E+ K+L + + QR A+L R K K
Sbjct: 1971 RQRQLAAEE----ERRRREAE--ERVQKSL--AAEEEAARQR----KAALEEVERLKAKV 2018
Query: 179 KHPRRAQDSKKPPRAPRTSKAQ 200
+ RR ++ + A + AQ
Sbjct: 2019 EEARRLRERAEQESARQLQLAQ 2040
Score = 28.1 bits (61), Expect = 5.8
Identities = 27/121 (22%), Positives = 46/121 (38%), Gaps = 10/121 (8%)
Query: 29 EYLTGFHKRKVERKKAAIEEIKQRLK----------EEQRKLREERHQEYLKMLAEREEA 78
E L R E ++ E+ KQRL+ EE +LR + + E+A
Sbjct: 1765 EVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDA 1824
Query: 79 LEEADELDRLVTAKTESVQYDHPNHTVTVTTISDLDLSGARLLGLTPPEGGAGDRSEEEA 138
+ E +R++ K ++ T + + + RL L E R EE+A
Sbjct: 1825 ARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQA 1884
Query: 139 S 139
+
Sbjct: 1885 A 1885
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 40.4 bits (93), Expect = 0.001
Identities = 35/129 (27%), Positives = 60/129 (46%), Gaps = 9/129 (6%)
Query: 36 KRKVERKKAAIEEI-------KQRLKEEQRKLREERHQEYLKMLAEREEALEEADELDRL 88
+R +E++KA +E++ Q+L+EEQ++ +++ QE +++A EEA E +
Sbjct: 2510 ERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEG 2569
Query: 89 VTAKTESVQYDHPNHTVTVTTISDLDLSGARLLGLTPPEGGAG-DRSEEEASSTEKPTKA 147
V K E +Q +++ + L L + A SEE +S TK
Sbjct: 2570 VRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKT 2629
Query: 148 LPRKSRDPL 156
LP RD L
Sbjct: 2630 LP-NGRDAL 2637
Score = 40.4 bits (93), Expect = 0.001
Identities = 25/95 (26%), Positives = 57/95 (60%), Gaps = 6/95 (6%)
Query: 5 KKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLREE- 63
+++++ + R RLV S +E +RR++ + V RK+ +++++Q+ ++++ L EE
Sbjct: 2539 QRQQQQMEQERQRLVASMEEARRRQHEA---EEGVRRKQEELQQLEQQRRQQEELLAEEN 2595
Query: 64 -RHQEYLKMLAEREE-ALEEADELDRLVTAKTESV 96
R +E L++L E+ AL ++E+ A T+++
Sbjct: 2596 QRLREQLQLLEEQHRAALAHSEEVTASQVAATKTL 2630
Score = 35.0 bits (79), Expect = 0.047
Identities = 43/199 (21%), Positives = 84/199 (42%), Gaps = 19/199 (9%)
Query: 20 LSFDEEKRR-------EYLTGFHKRKVERKKAAIEEIKQRLK---EEQRKLREERHQEYL 69
L+ +EE+RR + + ++KAA+EE+ +RLK EE R+LRE QE
Sbjct: 1979 LAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEV-ERLKAKVEEARRLRERAEQESA 2037
Query: 70 KMLAEREEALEEADELDR-----LVTAKTESVQYDHPNHTVTVTTISDLDLSGARLLGLT 124
+ L +EA ++ + + V K + +Q + + + AR
Sbjct: 2038 RQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRG-EAEAARRAAEE 2096
Query: 125 PPEGGAGDRSEEEASSTEKPTKALPRKSRDPLLSQRISSLTASLHAHSRKKVKRKHPRRA 184
E A ++E EA+ + + + R + + + + RK+ +++ RRA
Sbjct: 2097 AEE--ARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRA 2154
Query: 185 QDSKKPPRAPRTSKAQRRR 203
Q + R + + A+ +
Sbjct: 2155 QAEQAALRQKQAADAEMEK 2173
Score = 28.5 bits (62), Expect = 4.4
Identities = 17/40 (42%), Positives = 26/40 (65%), Gaps = 1/40 (2%)
Query: 46 IEEIKQRLKEEQRKLREERHQEYLKMLAEREEALEEADEL 85
I E +R++EE+R L E++ E + LAE E ALE+ +L
Sbjct: 1341 ISETLRRMEEEER-LAEQQRAEERERLAEVEAALEKQRQL 1379
Score = 28.5 bits (62), Expect = 4.4
Identities = 49/202 (24%), Positives = 87/202 (43%), Gaps = 29/202 (14%)
Query: 4 NKKKKRDGDD---RRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQR--LKEEQR 58
N++ +R +D +R RL EE+ ++ +R + +KA+ E++++ L E+
Sbjct: 1867 NERLRRLAEDEAFQRRRL-----EEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTL 1921
Query: 59 KLREERHQEYLKMLAEREEALEEADELDRLVTAKTESVQYDHPNHTVTVTTISDLDLSGA 118
+ R + +E L + A E+A EL+ L + S N T+ + +L A
Sbjct: 1922 RQRRQVEEEILALKASFEKAAAGKAELE-LELGRIRS------NAEDTLRSKEQAELEAA 1974
Query: 119 RLLGLTPPEGGAGDRSEEEASSTEKPTKALPRKSRDPLLSQRISSLTASLHAHSRKKVKR 178
R L E +R EA E+ K+L + + QR A+L R K K
Sbjct: 1975 RQRQLAAEE----ERRRREAE--ERVQKSL--AAEEEAARQR----KAALEEVERLKAKV 2022
Query: 179 KHPRRAQDSKKPPRAPRTSKAQ 200
+ RR ++ + A + AQ
Sbjct: 2023 EEARRLRERAEQESARQLQLAQ 2044
Score = 28.1 bits (61), Expect = 5.8
Identities = 27/121 (22%), Positives = 46/121 (38%), Gaps = 10/121 (8%)
Query: 29 EYLTGFHKRKVERKKAAIEEIKQRLK----------EEQRKLREERHQEYLKMLAEREEA 78
E L R E ++ E+ KQRL+ EE +LR + + E+A
Sbjct: 1769 EVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDA 1828
Query: 79 LEEADELDRLVTAKTESVQYDHPNHTVTVTTISDLDLSGARLLGLTPPEGGAGDRSEEEA 138
+ E +R++ K ++ T + + + RL L E R EE+A
Sbjct: 1829 ARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQA 1888
Query: 139 S 139
+
Sbjct: 1889 A 1889
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 40.4 bits (93), Expect = 0.001
Identities = 35/129 (27%), Positives = 60/129 (46%), Gaps = 9/129 (6%)
Query: 36 KRKVERKKAAIEEI-------KQRLKEEQRKLREERHQEYLKMLAEREEALEEADELDRL 88
+R +E++KA +E++ Q+L+EEQ++ +++ QE +++A EEA E +
Sbjct: 2506 ERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEG 2565
Query: 89 VTAKTESVQYDHPNHTVTVTTISDLDLSGARLLGLTPPEGGAG-DRSEEEASSTEKPTKA 147
V K E +Q +++ + L L + A SEE +S TK
Sbjct: 2566 VRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKT 2625
Query: 148 LPRKSRDPL 156
LP RD L
Sbjct: 2626 LP-NGRDAL 2633
Score = 40.4 bits (93), Expect = 0.001
Identities = 25/95 (26%), Positives = 57/95 (60%), Gaps = 6/95 (6%)
Query: 5 KKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLREE- 63
+++++ + R RLV S +E +RR++ + V RK+ +++++Q+ ++++ L EE
Sbjct: 2535 QRQQQQMEQERQRLVASMEEARRRQHEA---EEGVRRKQEELQQLEQQRRQQEELLAEEN 2591
Query: 64 -RHQEYLKMLAEREE-ALEEADELDRLVTAKTESV 96
R +E L++L E+ AL ++E+ A T+++
Sbjct: 2592 QRLREQLQLLEEQHRAALAHSEEVTASQVAATKTL 2626
Score = 35.0 bits (79), Expect = 0.047
Identities = 43/199 (21%), Positives = 84/199 (42%), Gaps = 19/199 (9%)
Query: 20 LSFDEEKRR-------EYLTGFHKRKVERKKAAIEEIKQRLK---EEQRKLREERHQEYL 69
L+ +EE+RR + + ++KAA+EE+ +RLK EE R+LRE QE
Sbjct: 1975 LAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEV-ERLKAKVEEARRLRERAEQESA 2033
Query: 70 KMLAEREEALEEADELDR-----LVTAKTESVQYDHPNHTVTVTTISDLDLSGARLLGLT 124
+ L +EA ++ + + V K + +Q + + + AR
Sbjct: 2034 RQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRG-EAEAARRAAEE 2092
Query: 125 PPEGGAGDRSEEEASSTEKPTKALPRKSRDPLLSQRISSLTASLHAHSRKKVKRKHPRRA 184
E A ++E EA+ + + + R + + + + RK+ +++ RRA
Sbjct: 2093 AEE--ARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRA 2150
Query: 185 QDSKKPPRAPRTSKAQRRR 203
Q + R + + A+ +
Sbjct: 2151 QAEQAALRQKQAADAEMEK 2169
Score = 28.5 bits (62), Expect = 4.4
Identities = 17/40 (42%), Positives = 26/40 (65%), Gaps = 1/40 (2%)
Query: 46 IEEIKQRLKEEQRKLREERHQEYLKMLAEREEALEEADEL 85
I E +R++EE+R L E++ E + LAE E ALE+ +L
Sbjct: 1337 ISETLRRMEEEER-LAEQQRAEERERLAEVEAALEKQRQL 1375
Score = 28.5 bits (62), Expect = 4.4
Identities = 49/202 (24%), Positives = 87/202 (43%), Gaps = 29/202 (14%)
Query: 4 NKKKKRDGDD---RRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQR--LKEEQR 58
N++ +R +D +R RL EE+ ++ +R + +KA+ E++++ L E+
Sbjct: 1863 NERLRRLAEDEAFQRRRL-----EEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTL 1917
Query: 59 KLREERHQEYLKMLAEREEALEEADELDRLVTAKTESVQYDHPNHTVTVTTISDLDLSGA 118
+ R + +E L + A E+A EL+ L + S N T+ + +L A
Sbjct: 1918 RQRRQVEEEILALKASFEKAAAGKAELE-LELGRIRS------NAEDTLRSKEQAELEAA 1970
Query: 119 RLLGLTPPEGGAGDRSEEEASSTEKPTKALPRKSRDPLLSQRISSLTASLHAHSRKKVKR 178
R L E +R EA E+ K+L + + QR A+L R K K
Sbjct: 1971 RQRQLAAEE----ERRRREAE--ERVQKSL--AAEEEAARQR----KAALEEVERLKAKV 2018
Query: 179 KHPRRAQDSKKPPRAPRTSKAQ 200
+ RR ++ + A + AQ
Sbjct: 2019 EEARRLRERAEQESARQLQLAQ 2040
Score = 28.1 bits (61), Expect = 5.8
Identities = 27/121 (22%), Positives = 46/121 (38%), Gaps = 10/121 (8%)
Query: 29 EYLTGFHKRKVERKKAAIEEIKQRLK----------EEQRKLREERHQEYLKMLAEREEA 78
E L R E ++ E+ KQRL+ EE +LR + + E+A
Sbjct: 1765 EVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDA 1824
Query: 79 LEEADELDRLVTAKTESVQYDHPNHTVTVTTISDLDLSGARLLGLTPPEGGAGDRSEEEA 138
+ E +R++ K ++ T + + + RL L E R EE+A
Sbjct: 1825 ARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQA 1884
Query: 139 S 139
+
Sbjct: 1885 A 1885
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 40.4 bits (93), Expect = 0.001
Identities = 35/129 (27%), Positives = 60/129 (46%), Gaps = 9/129 (6%)
Query: 36 KRKVERKKAAIEEI-------KQRLKEEQRKLREERHQEYLKMLAEREEALEEADELDRL 88
+R +E++KA +E++ Q+L+EEQ++ +++ QE +++A EEA E +
Sbjct: 2474 ERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEG 2533
Query: 89 VTAKTESVQYDHPNHTVTVTTISDLDLSGARLLGLTPPEGGAG-DRSEEEASSTEKPTKA 147
V K E +Q +++ + L L + A SEE +S TK
Sbjct: 2534 VRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKT 2593
Query: 148 LPRKSRDPL 156
LP RD L
Sbjct: 2594 LP-NGRDAL 2601
Score = 40.4 bits (93), Expect = 0.001
Identities = 25/95 (26%), Positives = 57/95 (60%), Gaps = 6/95 (6%)
Query: 5 KKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLREE- 63
+++++ + R RLV S +E +RR++ + V RK+ +++++Q+ ++++ L EE
Sbjct: 2503 QRQQQQMEQERQRLVASMEEARRRQHEA---EEGVRRKQEELQQLEQQRRQQEELLAEEN 2559
Query: 64 -RHQEYLKMLAEREE-ALEEADELDRLVTAKTESV 96
R +E L++L E+ AL ++E+ A T+++
Sbjct: 2560 QRLREQLQLLEEQHRAALAHSEEVTASQVAATKTL 2594
Score = 35.0 bits (79), Expect = 0.047
Identities = 43/199 (21%), Positives = 84/199 (42%), Gaps = 19/199 (9%)
Query: 20 LSFDEEKRR-------EYLTGFHKRKVERKKAAIEEIKQRLK---EEQRKLREERHQEYL 69
L+ +EE+RR + + ++KAA+EE+ +RLK EE R+LRE QE
Sbjct: 1943 LAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEV-ERLKAKVEEARRLRERAEQESA 2001
Query: 70 KMLAEREEALEEADELDR-----LVTAKTESVQYDHPNHTVTVTTISDLDLSGARLLGLT 124
+ L +EA ++ + + V K + +Q + + + AR
Sbjct: 2002 RQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRG-EAEAARRAAEE 2060
Query: 125 PPEGGAGDRSEEEASSTEKPTKALPRKSRDPLLSQRISSLTASLHAHSRKKVKRKHPRRA 184
E A ++E EA+ + + + R + + + + RK+ +++ RRA
Sbjct: 2061 AEE--ARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRA 2118
Query: 185 QDSKKPPRAPRTSKAQRRR 203
Q + R + + A+ +
Sbjct: 2119 QAEQAALRQKQAADAEMEK 2137
Score = 28.5 bits (62), Expect = 4.4
Identities = 17/40 (42%), Positives = 26/40 (65%), Gaps = 1/40 (2%)
Query: 46 IEEIKQRLKEEQRKLREERHQEYLKMLAEREEALEEADEL 85
I E +R++EE+R L E++ E + LAE E ALE+ +L
Sbjct: 1305 ISETLRRMEEEER-LAEQQRAEERERLAEVEAALEKQRQL 1343
Score = 28.5 bits (62), Expect = 4.4
Identities = 49/202 (24%), Positives = 87/202 (43%), Gaps = 29/202 (14%)
Query: 4 NKKKKRDGDD---RRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQR--LKEEQR 58
N++ +R +D +R RL EE+ ++ +R + +KA+ E++++ L E+
Sbjct: 1831 NERLRRLAEDEAFQRRRL-----EEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTL 1885
Query: 59 KLREERHQEYLKMLAEREEALEEADELDRLVTAKTESVQYDHPNHTVTVTTISDLDLSGA 118
+ R + +E L + A E+A EL+ L + S N T+ + +L A
Sbjct: 1886 RQRRQVEEEILALKASFEKAAAGKAELE-LELGRIRS------NAEDTLRSKEQAELEAA 1938
Query: 119 RLLGLTPPEGGAGDRSEEEASSTEKPTKALPRKSRDPLLSQRISSLTASLHAHSRKKVKR 178
R L E +R EA E+ K+L + + QR A+L R K K
Sbjct: 1939 RQRQLAAEE----ERRRREAE--ERVQKSL--AAEEEAARQR----KAALEEVERLKAKV 1986
Query: 179 KHPRRAQDSKKPPRAPRTSKAQ 200
+ RR ++ + A + AQ
Sbjct: 1987 EEARRLRERAEQESARQLQLAQ 2008
Score = 28.1 bits (61), Expect = 5.8
Identities = 27/121 (22%), Positives = 46/121 (38%), Gaps = 10/121 (8%)
Query: 29 EYLTGFHKRKVERKKAAIEEIKQRLK----------EEQRKLREERHQEYLKMLAEREEA 78
E L R E ++ E+ KQRL+ EE +LR + + E+A
Sbjct: 1733 EVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDA 1792
Query: 79 LEEADELDRLVTAKTESVQYDHPNHTVTVTTISDLDLSGARLLGLTPPEGGAGDRSEEEA 138
+ E +R++ K ++ T + + + RL L E R EE+A
Sbjct: 1793 ARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQA 1852
Query: 139 S 139
+
Sbjct: 1853 A 1853
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 40.4 bits (93), Expect = 0.001
Identities = 35/129 (27%), Positives = 60/129 (46%), Gaps = 9/129 (6%)
Query: 36 KRKVERKKAAIEEI-------KQRLKEEQRKLREERHQEYLKMLAEREEALEEADELDRL 88
+R +E++KA +E++ Q+L+EEQ++ +++ QE +++A EEA E +
Sbjct: 2643 ERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEG 2702
Query: 89 VTAKTESVQYDHPNHTVTVTTISDLDLSGARLLGLTPPEGGAG-DRSEEEASSTEKPTKA 147
V K E +Q +++ + L L + A SEE +S TK
Sbjct: 2703 VRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKT 2762
Query: 148 LPRKSRDPL 156
LP RD L
Sbjct: 2763 LP-NGRDAL 2770
Score = 40.4 bits (93), Expect = 0.001
Identities = 25/95 (26%), Positives = 57/95 (60%), Gaps = 6/95 (6%)
Query: 5 KKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLREE- 63
+++++ + R RLV S +E +RR++ + V RK+ +++++Q+ ++++ L EE
Sbjct: 2672 QRQQQQMEQERQRLVASMEEARRRQHEA---EEGVRRKQEELQQLEQQRRQQEELLAEEN 2728
Query: 64 -RHQEYLKMLAEREE-ALEEADELDRLVTAKTESV 96
R +E L++L E+ AL ++E+ A T+++
Sbjct: 2729 QRLREQLQLLEEQHRAALAHSEEVTASQVAATKTL 2763
Score = 35.0 bits (79), Expect = 0.047
Identities = 43/199 (21%), Positives = 84/199 (42%), Gaps = 19/199 (9%)
Query: 20 LSFDEEKRR-------EYLTGFHKRKVERKKAAIEEIKQRLK---EEQRKLREERHQEYL 69
L+ +EE+RR + + ++KAA+EE+ +RLK EE R+LRE QE
Sbjct: 2112 LAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEV-ERLKAKVEEARRLRERAEQESA 2170
Query: 70 KMLAEREEALEEADELDR-----LVTAKTESVQYDHPNHTVTVTTISDLDLSGARLLGLT 124
+ L +EA ++ + + V K + +Q + + + AR
Sbjct: 2171 RQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRG-EAEAARRAAEE 2229
Query: 125 PPEGGAGDRSEEEASSTEKPTKALPRKSRDPLLSQRISSLTASLHAHSRKKVKRKHPRRA 184
E A ++E EA+ + + + R + + + + RK+ +++ RRA
Sbjct: 2230 AEE--ARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRA 2287
Query: 185 QDSKKPPRAPRTSKAQRRR 203
Q + R + + A+ +
Sbjct: 2288 QAEQAALRQKQAADAEMEK 2306
Score = 28.5 bits (62), Expect = 4.4
Identities = 17/40 (42%), Positives = 26/40 (65%), Gaps = 1/40 (2%)
Query: 46 IEEIKQRLKEEQRKLREERHQEYLKMLAEREEALEEADEL 85
I E +R++EE+R L E++ E + LAE E ALE+ +L
Sbjct: 1474 ISETLRRMEEEER-LAEQQRAEERERLAEVEAALEKQRQL 1512
Score = 28.5 bits (62), Expect = 4.4
Identities = 49/202 (24%), Positives = 87/202 (43%), Gaps = 29/202 (14%)
Query: 4 NKKKKRDGDD---RRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQR--LKEEQR 58
N++ +R +D +R RL EE+ ++ +R + +KA+ E++++ L E+
Sbjct: 2000 NERLRRLAEDEAFQRRRL-----EEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTL 2054
Query: 59 KLREERHQEYLKMLAEREEALEEADELDRLVTAKTESVQYDHPNHTVTVTTISDLDLSGA 118
+ R + +E L + A E+A EL+ L + S N T+ + +L A
Sbjct: 2055 RQRRQVEEEILALKASFEKAAAGKAELE-LELGRIRS------NAEDTLRSKEQAELEAA 2107
Query: 119 RLLGLTPPEGGAGDRSEEEASSTEKPTKALPRKSRDPLLSQRISSLTASLHAHSRKKVKR 178
R L E +R EA E+ K+L + + QR A+L R K K
Sbjct: 2108 RQRQLAAEE----ERRRREAE--ERVQKSL--AAEEEAARQR----KAALEEVERLKAKV 2155
Query: 179 KHPRRAQDSKKPPRAPRTSKAQ 200
+ RR ++ + A + AQ
Sbjct: 2156 EEARRLRERAEQESARQLQLAQ 2177
Score = 28.1 bits (61), Expect = 5.8
Identities = 27/121 (22%), Positives = 46/121 (38%), Gaps = 10/121 (8%)
Query: 29 EYLTGFHKRKVERKKAAIEEIKQRLK----------EEQRKLREERHQEYLKMLAEREEA 78
E L R E ++ E+ KQRL+ EE +LR + + E+A
Sbjct: 1902 EVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDA 1961
Query: 79 LEEADELDRLVTAKTESVQYDHPNHTVTVTTISDLDLSGARLLGLTPPEGGAGDRSEEEA 138
+ E +R++ K ++ T + + + RL L E R EE+A
Sbjct: 1962 ARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQA 2021
Query: 139 S 139
+
Sbjct: 2022 A 2022
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 40.4 bits (93), Expect = 0.001
Identities = 35/129 (27%), Positives = 60/129 (46%), Gaps = 9/129 (6%)
Query: 36 KRKVERKKAAIEEI-------KQRLKEEQRKLREERHQEYLKMLAEREEALEEADELDRL 88
+R +E++KA +E++ Q+L+EEQ++ +++ QE +++A EEA E +
Sbjct: 2484 ERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEG 2543
Query: 89 VTAKTESVQYDHPNHTVTVTTISDLDLSGARLLGLTPPEGGAG-DRSEEEASSTEKPTKA 147
V K E +Q +++ + L L + A SEE +S TK
Sbjct: 2544 VRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKT 2603
Query: 148 LPRKSRDPL 156
LP RD L
Sbjct: 2604 LP-NGRDAL 2611
Score = 40.4 bits (93), Expect = 0.001
Identities = 25/95 (26%), Positives = 57/95 (60%), Gaps = 6/95 (6%)
Query: 5 KKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLREE- 63
+++++ + R RLV S +E +RR++ + V RK+ +++++Q+ ++++ L EE
Sbjct: 2513 QRQQQQMEQERQRLVASMEEARRRQHEA---EEGVRRKQEELQQLEQQRRQQEELLAEEN 2569
Query: 64 -RHQEYLKMLAEREE-ALEEADELDRLVTAKTESV 96
R +E L++L E+ AL ++E+ A T+++
Sbjct: 2570 QRLREQLQLLEEQHRAALAHSEEVTASQVAATKTL 2604
Score = 35.0 bits (79), Expect = 0.047
Identities = 43/199 (21%), Positives = 84/199 (42%), Gaps = 19/199 (9%)
Query: 20 LSFDEEKRR-------EYLTGFHKRKVERKKAAIEEIKQRLK---EEQRKLREERHQEYL 69
L+ +EE+RR + + ++KAA+EE+ +RLK EE R+LRE QE
Sbjct: 1953 LAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEV-ERLKAKVEEARRLRERAEQESA 2011
Query: 70 KMLAEREEALEEADELDR-----LVTAKTESVQYDHPNHTVTVTTISDLDLSGARLLGLT 124
+ L +EA ++ + + V K + +Q + + + AR
Sbjct: 2012 RQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRG-EAEAARRAAEE 2070
Query: 125 PPEGGAGDRSEEEASSTEKPTKALPRKSRDPLLSQRISSLTASLHAHSRKKVKRKHPRRA 184
E A ++E EA+ + + + R + + + + RK+ +++ RRA
Sbjct: 2071 AEE--ARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRA 2128
Query: 185 QDSKKPPRAPRTSKAQRRR 203
Q + R + + A+ +
Sbjct: 2129 QAEQAALRQKQAADAEMEK 2147
Score = 28.5 bits (62), Expect = 4.4
Identities = 17/40 (42%), Positives = 26/40 (65%), Gaps = 1/40 (2%)
Query: 46 IEEIKQRLKEEQRKLREERHQEYLKMLAEREEALEEADEL 85
I E +R++EE+R L E++ E + LAE E ALE+ +L
Sbjct: 1315 ISETLRRMEEEER-LAEQQRAEERERLAEVEAALEKQRQL 1353
Score = 28.5 bits (62), Expect = 4.4
Identities = 49/202 (24%), Positives = 87/202 (43%), Gaps = 29/202 (14%)
Query: 4 NKKKKRDGDD---RRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQR--LKEEQR 58
N++ +R +D +R RL EE+ ++ +R + +KA+ E++++ L E+
Sbjct: 1841 NERLRRLAEDEAFQRRRL-----EEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTL 1895
Query: 59 KLREERHQEYLKMLAEREEALEEADELDRLVTAKTESVQYDHPNHTVTVTTISDLDLSGA 118
+ R + +E L + A E+A EL+ L + S N T+ + +L A
Sbjct: 1896 RQRRQVEEEILALKASFEKAAAGKAELE-LELGRIRS------NAEDTLRSKEQAELEAA 1948
Query: 119 RLLGLTPPEGGAGDRSEEEASSTEKPTKALPRKSRDPLLSQRISSLTASLHAHSRKKVKR 178
R L E +R EA E+ K+L + + QR A+L R K K
Sbjct: 1949 RQRQLAAEE----ERRRREAE--ERVQKSL--AAEEEAARQR----KAALEEVERLKAKV 1996
Query: 179 KHPRRAQDSKKPPRAPRTSKAQ 200
+ RR ++ + A + AQ
Sbjct: 1997 EEARRLRERAEQESARQLQLAQ 2018
Score = 28.1 bits (61), Expect = 5.8
Identities = 27/121 (22%), Positives = 46/121 (38%), Gaps = 10/121 (8%)
Query: 29 EYLTGFHKRKVERKKAAIEEIKQRLK----------EEQRKLREERHQEYLKMLAEREEA 78
E L R E ++ E+ KQRL+ EE +LR + + E+A
Sbjct: 1743 EVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDA 1802
Query: 79 LEEADELDRLVTAKTESVQYDHPNHTVTVTTISDLDLSGARLLGLTPPEGGAGDRSEEEA 138
+ E +R++ K ++ T + + + RL L E R EE+A
Sbjct: 1803 ARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQA 1862
Query: 139 S 139
+
Sbjct: 1863 A 1863
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 40.4 bits (93), Expect = 0.001
Identities = 35/129 (27%), Positives = 60/129 (46%), Gaps = 9/129 (6%)
Query: 36 KRKVERKKAAIEEI-------KQRLKEEQRKLREERHQEYLKMLAEREEALEEADELDRL 88
+R +E++KA +E++ Q+L+EEQ++ +++ QE +++A EEA E +
Sbjct: 2492 ERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEG 2551
Query: 89 VTAKTESVQYDHPNHTVTVTTISDLDLSGARLLGLTPPEGGAG-DRSEEEASSTEKPTKA 147
V K E +Q +++ + L L + A SEE +S TK
Sbjct: 2552 VRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKT 2611
Query: 148 LPRKSRDPL 156
LP RD L
Sbjct: 2612 LP-NGRDAL 2619
Score = 40.4 bits (93), Expect = 0.001
Identities = 25/95 (26%), Positives = 57/95 (60%), Gaps = 6/95 (6%)
Query: 5 KKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLREE- 63
+++++ + R RLV S +E +RR++ + V RK+ +++++Q+ ++++ L EE
Sbjct: 2521 QRQQQQMEQERQRLVASMEEARRRQHEA---EEGVRRKQEELQQLEQQRRQQEELLAEEN 2577
Query: 64 -RHQEYLKMLAEREE-ALEEADELDRLVTAKTESV 96
R +E L++L E+ AL ++E+ A T+++
Sbjct: 2578 QRLREQLQLLEEQHRAALAHSEEVTASQVAATKTL 2612
Score = 35.0 bits (79), Expect = 0.047
Identities = 43/199 (21%), Positives = 84/199 (42%), Gaps = 19/199 (9%)
Query: 20 LSFDEEKRR-------EYLTGFHKRKVERKKAAIEEIKQRLK---EEQRKLREERHQEYL 69
L+ +EE+RR + + ++KAA+EE+ +RLK EE R+LRE QE
Sbjct: 1961 LAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEV-ERLKAKVEEARRLRERAEQESA 2019
Query: 70 KMLAEREEALEEADELDR-----LVTAKTESVQYDHPNHTVTVTTISDLDLSGARLLGLT 124
+ L +EA ++ + + V K + +Q + + + AR
Sbjct: 2020 RQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRG-EAEAARRAAEE 2078
Query: 125 PPEGGAGDRSEEEASSTEKPTKALPRKSRDPLLSQRISSLTASLHAHSRKKVKRKHPRRA 184
E A ++E EA+ + + + R + + + + RK+ +++ RRA
Sbjct: 2079 AEE--ARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRA 2136
Query: 185 QDSKKPPRAPRTSKAQRRR 203
Q + R + + A+ +
Sbjct: 2137 QAEQAALRQKQAADAEMEK 2155
Score = 28.5 bits (62), Expect = 4.4
Identities = 17/40 (42%), Positives = 26/40 (65%), Gaps = 1/40 (2%)
Query: 46 IEEIKQRLKEEQRKLREERHQEYLKMLAEREEALEEADEL 85
I E +R++EE+R L E++ E + LAE E ALE+ +L
Sbjct: 1323 ISETLRRMEEEER-LAEQQRAEERERLAEVEAALEKQRQL 1361
Score = 28.5 bits (62), Expect = 4.4
Identities = 49/202 (24%), Positives = 87/202 (43%), Gaps = 29/202 (14%)
Query: 4 NKKKKRDGDD---RRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQR--LKEEQR 58
N++ +R +D +R RL EE+ ++ +R + +KA+ E++++ L E+
Sbjct: 1849 NERLRRLAEDEAFQRRRL-----EEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTL 1903
Query: 59 KLREERHQEYLKMLAEREEALEEADELDRLVTAKTESVQYDHPNHTVTVTTISDLDLSGA 118
+ R + +E L + A E+A EL+ L + S N T+ + +L A
Sbjct: 1904 RQRRQVEEEILALKASFEKAAAGKAELE-LELGRIRS------NAEDTLRSKEQAELEAA 1956
Query: 119 RLLGLTPPEGGAGDRSEEEASSTEKPTKALPRKSRDPLLSQRISSLTASLHAHSRKKVKR 178
R L E +R EA E+ K+L + + QR A+L R K K
Sbjct: 1957 RQRQLAAEE----ERRRREAE--ERVQKSL--AAEEEAARQR----KAALEEVERLKAKV 2004
Query: 179 KHPRRAQDSKKPPRAPRTSKAQ 200
+ RR ++ + A + AQ
Sbjct: 2005 EEARRLRERAEQESARQLQLAQ 2026
Score = 28.1 bits (61), Expect = 5.8
Identities = 27/121 (22%), Positives = 46/121 (38%), Gaps = 10/121 (8%)
Query: 29 EYLTGFHKRKVERKKAAIEEIKQRLK----------EEQRKLREERHQEYLKMLAEREEA 78
E L R E ++ E+ KQRL+ EE +LR + + E+A
Sbjct: 1751 EVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDA 1810
Query: 79 LEEADELDRLVTAKTESVQYDHPNHTVTVTTISDLDLSGARLLGLTPPEGGAGDRSEEEA 138
+ E +R++ K ++ T + + + RL L E R EE+A
Sbjct: 1811 ARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQA 1870
Query: 139 S 139
+
Sbjct: 1871 A 1871
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 40.4 bits (93), Expect = 0.001
Identities = 35/129 (27%), Positives = 60/129 (46%), Gaps = 9/129 (6%)
Query: 36 KRKVERKKAAIEEI-------KQRLKEEQRKLREERHQEYLKMLAEREEALEEADELDRL 88
+R +E++KA +E++ Q+L+EEQ++ +++ QE +++A EEA E +
Sbjct: 2533 ERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEG 2592
Query: 89 VTAKTESVQYDHPNHTVTVTTISDLDLSGARLLGLTPPEGGAG-DRSEEEASSTEKPTKA 147
V K E +Q +++ + L L + A SEE +S TK
Sbjct: 2593 VRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKT 2652
Query: 148 LPRKSRDPL 156
LP RD L
Sbjct: 2653 LP-NGRDAL 2660
Score = 40.4 bits (93), Expect = 0.001
Identities = 25/95 (26%), Positives = 57/95 (60%), Gaps = 6/95 (6%)
Query: 5 KKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLREE- 63
+++++ + R RLV S +E +RR++ + V RK+ +++++Q+ ++++ L EE
Sbjct: 2562 QRQQQQMEQERQRLVASMEEARRRQHEA---EEGVRRKQEELQQLEQQRRQQEELLAEEN 2618
Query: 64 -RHQEYLKMLAEREE-ALEEADELDRLVTAKTESV 96
R +E L++L E+ AL ++E+ A T+++
Sbjct: 2619 QRLREQLQLLEEQHRAALAHSEEVTASQVAATKTL 2653
Score = 35.0 bits (79), Expect = 0.047
Identities = 43/199 (21%), Positives = 84/199 (42%), Gaps = 19/199 (9%)
Query: 20 LSFDEEKRR-------EYLTGFHKRKVERKKAAIEEIKQRLK---EEQRKLREERHQEYL 69
L+ +EE+RR + + ++KAA+EE+ +RLK EE R+LRE QE
Sbjct: 2002 LAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEV-ERLKAKVEEARRLRERAEQESA 2060
Query: 70 KMLAEREEALEEADELDR-----LVTAKTESVQYDHPNHTVTVTTISDLDLSGARLLGLT 124
+ L +EA ++ + + V K + +Q + + + AR
Sbjct: 2061 RQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRG-EAEAARRAAEE 2119
Query: 125 PPEGGAGDRSEEEASSTEKPTKALPRKSRDPLLSQRISSLTASLHAHSRKKVKRKHPRRA 184
E A ++E EA+ + + + R + + + + RK+ +++ RRA
Sbjct: 2120 AEE--ARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRA 2177
Query: 185 QDSKKPPRAPRTSKAQRRR 203
Q + R + + A+ +
Sbjct: 2178 QAEQAALRQKQAADAEMEK 2196
Score = 28.5 bits (62), Expect = 4.4
Identities = 17/40 (42%), Positives = 26/40 (65%), Gaps = 1/40 (2%)
Query: 46 IEEIKQRLKEEQRKLREERHQEYLKMLAEREEALEEADEL 85
I E +R++EE+R L E++ E + LAE E ALE+ +L
Sbjct: 1364 ISETLRRMEEEER-LAEQQRAEERERLAEVEAALEKQRQL 1402
Score = 28.5 bits (62), Expect = 4.4
Identities = 49/202 (24%), Positives = 87/202 (43%), Gaps = 29/202 (14%)
Query: 4 NKKKKRDGDD---RRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQR--LKEEQR 58
N++ +R +D +R RL EE+ ++ +R + +KA+ E++++ L E+
Sbjct: 1890 NERLRRLAEDEAFQRRRL-----EEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTL 1944
Query: 59 KLREERHQEYLKMLAEREEALEEADELDRLVTAKTESVQYDHPNHTVTVTTISDLDLSGA 118
+ R + +E L + A E+A EL+ L + S N T+ + +L A
Sbjct: 1945 RQRRQVEEEILALKASFEKAAAGKAELE-LELGRIRS------NAEDTLRSKEQAELEAA 1997
Query: 119 RLLGLTPPEGGAGDRSEEEASSTEKPTKALPRKSRDPLLSQRISSLTASLHAHSRKKVKR 178
R L E +R EA E+ K+L + + QR A+L R K K
Sbjct: 1998 RQRQLAAEE----ERRRREAE--ERVQKSL--AAEEEAARQR----KAALEEVERLKAKV 2045
Query: 179 KHPRRAQDSKKPPRAPRTSKAQ 200
+ RR ++ + A + AQ
Sbjct: 2046 EEARRLRERAEQESARQLQLAQ 2067
Score = 28.1 bits (61), Expect = 5.8
Identities = 27/121 (22%), Positives = 46/121 (38%), Gaps = 10/121 (8%)
Query: 29 EYLTGFHKRKVERKKAAIEEIKQRLK----------EEQRKLREERHQEYLKMLAEREEA 78
E L R E ++ E+ KQRL+ EE +LR + + E+A
Sbjct: 1792 EVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDA 1851
Query: 79 LEEADELDRLVTAKTESVQYDHPNHTVTVTTISDLDLSGARLLGLTPPEGGAGDRSEEEA 138
+ E +R++ K ++ T + + + RL L E R EE+A
Sbjct: 1852 ARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQA 1911
Query: 139 S 139
+
Sbjct: 1912 A 1912
>gi|32967605 bromodomain adjacent to zinc finger domain, 1A isoform
b [Homo sapiens]
Length = 1524
Score = 40.0 bits (92), Expect = 0.001
Identities = 28/86 (32%), Positives = 45/86 (52%), Gaps = 3/86 (3%)
Query: 5 KKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLREER 64
K K+ D + D+EK+RE L + + +KK E +K ++E+ KLREE+
Sbjct: 326 KLKREKADALEAKKKEKEDKEKKREELKKIVEEERLKKKEEKERLKVEREKEREKLREEK 385
Query: 65 HQ--EYLKMLAEREEALEEADELDRL 88
+ EYLK ++ E + E D+L L
Sbjct: 386 RKYVEYLKQWSKPREDM-ECDDLKEL 410
Score = 37.0 bits (84), Expect = 0.012
Identities = 25/70 (35%), Positives = 39/70 (55%), Gaps = 5/70 (7%)
Query: 34 FHKRKVERKKAAIEEIKQRLKEEQRKLREER----HQEYLKMLAEREE-ALEEADELDRL 88
F K K++R+KA E K++ KE++ K REE +E LK E+E +E E ++L
Sbjct: 322 FEKAKLKREKADALEAKKKEKEDKEKKREELKKIVEEERLKKKEEKERLKVEREKEREKL 381
Query: 89 VTAKTESVQY 98
K + V+Y
Sbjct: 382 REEKRKYVEY 391
Score = 32.0 bits (71), Expect = 0.40
Identities = 19/59 (32%), Positives = 32/59 (54%), Gaps = 4/59 (6%)
Query: 25 EKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLREERHQEYLKMLAEREEALEEAD 83
++R E KRK E+ K E +Q++KE+Q KL+E+ + ++ EE E+ D
Sbjct: 626 KEREEAAARIRKRKEEKLK----EQEQKMKEKQEKLKEDEQRNSTADISIGEEEREDFD 680
Score = 27.3 bits (59), Expect = 9.9
Identities = 21/99 (21%), Positives = 42/99 (42%), Gaps = 18/99 (18%)
Query: 1 MGRNKKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQ--------- 51
M ++K ++ + R +S EE+R ++ T + E+K+ + + +
Sbjct: 650 MKEKQEKLKEDEQRNSTADISIGEEEREDFDTSIESKDTEQKELDQDMVTEDEDDPGSHK 709
Query: 52 ---RLKEEQRKLREERHQEYLK------MLAEREEALEE 81
R K Q +E QE + + A+ EEAL++
Sbjct: 710 RGRRGKRGQNGFKEFTRQEQINCVTREPLTADEEEALKQ 748
>gi|32967603 bromodomain adjacent to zinc finger domain, 1A isoform
a [Homo sapiens]
Length = 1556
Score = 40.0 bits (92), Expect = 0.001
Identities = 28/86 (32%), Positives = 45/86 (52%), Gaps = 3/86 (3%)
Query: 5 KKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLREER 64
K K+ D + D+EK+RE L + + +KK E +K ++E+ KLREE+
Sbjct: 326 KLKREKADALEAKKKEKEDKEKKREELKKIVEEERLKKKEEKERLKVEREKEREKLREEK 385
Query: 65 HQ--EYLKMLAEREEALEEADELDRL 88
+ EYLK ++ E + E D+L L
Sbjct: 386 RKYVEYLKQWSKPREDM-ECDDLKEL 410
Score = 37.0 bits (84), Expect = 0.012
Identities = 25/70 (35%), Positives = 39/70 (55%), Gaps = 5/70 (7%)
Query: 34 FHKRKVERKKAAIEEIKQRLKEEQRKLREER----HQEYLKMLAEREE-ALEEADELDRL 88
F K K++R+KA E K++ KE++ K REE +E LK E+E +E E ++L
Sbjct: 322 FEKAKLKREKADALEAKKKEKEDKEKKREELKKIVEEERLKKKEEKERLKVEREKEREKL 381
Query: 89 VTAKTESVQY 98
K + V+Y
Sbjct: 382 REEKRKYVEY 391
Score = 32.0 bits (71), Expect = 0.40
Identities = 19/59 (32%), Positives = 32/59 (54%), Gaps = 4/59 (6%)
Query: 25 EKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLREERHQEYLKMLAEREEALEEAD 83
++R E KRK E+ K E +Q++KE+Q KL+E+ + ++ EE E+ D
Sbjct: 658 KEREEAAARIRKRKEEKLK----EQEQKMKEKQEKLKEDEQRNSTADISIGEEEREDFD 712
Score = 27.3 bits (59), Expect = 9.9
Identities = 21/99 (21%), Positives = 42/99 (42%), Gaps = 18/99 (18%)
Query: 1 MGRNKKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQ--------- 51
M ++K ++ + R +S EE+R ++ T + E+K+ + + +
Sbjct: 682 MKEKQEKLKEDEQRNSTADISIGEEEREDFDTSIESKDTEQKELDQDMVTEDEDDPGSHK 741
Query: 52 ---RLKEEQRKLREERHQEYLK------MLAEREEALEE 81
R K Q +E QE + + A+ EEAL++
Sbjct: 742 RGRRGKRGQNGFKEFTRQEQINCVTREPLTADEEEALKQ 780
>gi|194578896 golgi autoantigen, golgin subfamily a, 8E [Homo
sapiens]
Length = 430
Score = 40.0 bits (92), Expect = 0.001
Identities = 27/113 (23%), Positives = 54/113 (47%), Gaps = 5/113 (4%)
Query: 40 ERKKAAIEEIKQRLKEEQRKLREERHQEYLKMLAEREEALEEADELDRLV---TAKTESV 96
E +K + E ++RL+E+Q +LRE+ +E L+ LAE + + +E + ++ V + + +
Sbjct: 132 EGQKERLREQEERLQEQQERLREQ--EERLQQLAEPQNSFKELNNENKSVLQLEQQVKEL 189
Query: 97 QYDHPNHTVTVTTISDLDLSGARLLGLTPPEGGAGDRSEEEASSTEKPTKALP 149
Q + + L+ L P EG G+ + E +P ++P
Sbjct: 190 QEKLGKERLEAASQQKQQLTAQLSLMALPGEGHGGEHLDSEGEEAPRPMPSVP 242
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 40.0 bits (92), Expect = 0.001
Identities = 42/163 (25%), Positives = 78/163 (47%), Gaps = 13/163 (7%)
Query: 3 RNKKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLRE 62
R ++++R+ + R L+ ++E+RRE +R+++ ++ A+ K++L QR+L E
Sbjct: 702 RREQERREQERREQERQLA-EQERRREQERLQAERELQEREKALRLQKEQL---QRELEE 757
Query: 63 ERHQEYLKMLAER---EEALEEADELDRLVTAKTESVQYDHPNHTVTVTTISDLDLSGAR 119
++ +E + LAER EE ++A E A +V P T + G R
Sbjct: 758 KKKKEEQQRLAERQLQEEQEKKAKEAAGASKALNVTVDVQSP-----ACTSYQMTPQGHR 812
Query: 120 LLGLTPPEGGAGDRSEEEASSTE-KPTKALPRKSRDPLLSQRI 161
P+ D + ++++ E P K +P +R LSQ I
Sbjct: 813 APPKINPDNYGMDLNSDDSTDDEAHPRKPIPTWARGTPLSQAI 855
Score = 39.7 bits (91), Expect = 0.002
Identities = 45/198 (22%), Positives = 86/198 (43%), Gaps = 15/198 (7%)
Query: 21 SFDEEKRREYLTGFHKRKVER-KKAAIEEIKQRLKEEQRKLREERHQEYLKMLAEREEAL 79
SF E++R+ K + E+ ++ +EE K+R EE + REER + K+L RE
Sbjct: 533 SFVEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLR---KVLQARERVE 589
Query: 80 EEADELDRLVTAKTESVQYDHPNHTVTVTTISDLDLSGARLLGLTPPEGGAGDRSEEEA- 138
+ +E + + K Q D +++ + + + E A + EEEA
Sbjct: 590 QMKEEKKKQIEQK--FAQIDEKTEKAKEERLAE-EKAKKKAAAKKMEEVEARRKQEEEAR 646
Query: 139 -------SSTEKPTKALPRKSRDPLLSQRISSLTASLHAHSRKKVKRKHPRRAQDSKKPP 191
E+ + L +K ++ + + A A R++ +R+ RR Q+ ++
Sbjct: 647 RLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQE 706
Query: 192 RAPRTSKAQRRRLTGKAR 209
R + + Q R+L + R
Sbjct: 707 RREQERREQERQLAEQER 724
Score = 35.8 bits (81), Expect = 0.028
Identities = 27/98 (27%), Positives = 46/98 (46%), Gaps = 8/98 (8%)
Query: 5 KKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLR--- 61
++KK+ + + ++ ++ K K+K KK E +++ +EE R+LR
Sbjct: 593 EEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQ 652
Query: 62 ----EERHQEYL-KMLAEREEALEEADELDRLVTAKTE 94
E RHQE L K E +E L +A E RL + +
Sbjct: 653 QEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQ 690
Score = 35.4 bits (80), Expect = 0.036
Identities = 27/95 (28%), Positives = 51/95 (53%), Gaps = 8/95 (8%)
Query: 5 KKKKRDGDDR------RPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQR 58
+KKK + +R RL ++E+R + +R+ ER++ E +++L E++R
Sbjct: 665 QKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQER 724
Query: 59 KLREERHQEYLKMLAEREEALE-EADELDRLVTAK 92
+ +ER Q + L ERE+AL + ++L R + K
Sbjct: 725 RREQERLQAE-RELQEREKALRLQKEQLQRELEEK 758
Score = 34.3 bits (77), Expect = 0.081
Identities = 25/89 (28%), Positives = 44/89 (49%), Gaps = 9/89 (10%)
Query: 6 KKKRDGDDRRPRLVLSFDEEKRREYLTGFHK-------RKVERKKAAIEEIKQRLKEEQR 58
++K++ + RR R + +EE+R + L K RK K E+ +Q +E++R
Sbjct: 638 RRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQER 697
Query: 59 KLREERHQEYLKMLAEREEALEEADELDR 87
+ +E R QE + ER E + E +R
Sbjct: 698 REQERREQE--RREQERREQERQLAEQER 724
Score = 32.7 bits (73), Expect = 0.24
Identities = 22/87 (25%), Positives = 41/87 (47%)
Query: 14 RRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLREERHQEYLKMLA 73
R RL +R E + K+++E+K A I+E ++ KEE+ + + + K +
Sbjct: 574 REERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKME 633
Query: 74 EREEALEEADELDRLVTAKTESVQYDH 100
E E ++ +E RL + E + H
Sbjct: 634 EVEARRKQEEEARRLRWLQQEEEERRH 660
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 40.0 bits (92), Expect = 0.001
Identities = 42/163 (25%), Positives = 78/163 (47%), Gaps = 13/163 (7%)
Query: 3 RNKKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLRE 62
R ++++R+ + R L+ ++E+RRE +R+++ ++ A+ K++L QR+L E
Sbjct: 698 RREQERREQERREQERQLA-EQERRREQERLQAERELQEREKALRLQKEQL---QRELEE 753
Query: 63 ERHQEYLKMLAER---EEALEEADELDRLVTAKTESVQYDHPNHTVTVTTISDLDLSGAR 119
++ +E + LAER EE ++A E A +V P T + G R
Sbjct: 754 KKKKEEQQRLAERQLQEEQEKKAKEAAGASKALNVTVDVQSP-----ACTSYQMTPQGHR 808
Query: 120 LLGLTPPEGGAGDRSEEEASSTE-KPTKALPRKSRDPLLSQRI 161
P+ D + ++++ E P K +P +R LSQ I
Sbjct: 809 APPKINPDNYGMDLNSDDSTDDEAHPRKPIPTWARGTPLSQAI 851
Score = 39.7 bits (91), Expect = 0.002
Identities = 43/196 (21%), Positives = 85/196 (43%), Gaps = 16/196 (8%)
Query: 24 EEKRREYLTGFHKRKV--ERKKAAIEEIKQRLKEEQRKLREERHQEYLKMLAEREEALEE 81
+EK R+ L +++ + ++ +EE K+R EE + REER + K+L RE +
Sbjct: 531 KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLR---KVLQARERVEQM 587
Query: 82 ADELDRLVTAKTESVQYDHPNHTVTVTTISDLDLSGARLLGLTPPEGGAGDRSEEEA--- 138
+E + + K Q D +++ + + + E A + EEEA
Sbjct: 588 KEEKKKQIEQK--FAQIDEKTEKAKEERLAE-EKAKKKAAAKKMEEVEARRKQEEEARRL 644
Query: 139 -----SSTEKPTKALPRKSRDPLLSQRISSLTASLHAHSRKKVKRKHPRRAQDSKKPPRA 193
E+ + L +K ++ + + A A R++ +R+ RR Q+ ++ R
Sbjct: 645 RWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERR 704
Query: 194 PRTSKAQRRRLTGKAR 209
+ + Q R+L + R
Sbjct: 705 EQERREQERQLAEQER 720
Score = 35.8 bits (81), Expect = 0.028
Identities = 27/98 (27%), Positives = 46/98 (46%), Gaps = 8/98 (8%)
Query: 5 KKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLR--- 61
++KK+ + + ++ ++ K K+K KK E +++ +EE R+LR
Sbjct: 589 EEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQ 648
Query: 62 ----EERHQEYL-KMLAEREEALEEADELDRLVTAKTE 94
E RHQE L K E +E L +A E RL + +
Sbjct: 649 QEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQ 686
Score = 35.4 bits (80), Expect = 0.036
Identities = 27/95 (28%), Positives = 51/95 (53%), Gaps = 8/95 (8%)
Query: 5 KKKKRDGDDR------RPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQR 58
+KKK + +R RL ++E+R + +R+ ER++ E +++L E++R
Sbjct: 661 QKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQER 720
Query: 59 KLREERHQEYLKMLAEREEALE-EADELDRLVTAK 92
+ +ER Q + L ERE+AL + ++L R + K
Sbjct: 721 RREQERLQAE-RELQEREKALRLQKEQLQRELEEK 754
Score = 34.3 bits (77), Expect = 0.081
Identities = 25/89 (28%), Positives = 44/89 (49%), Gaps = 9/89 (10%)
Query: 6 KKKRDGDDRRPRLVLSFDEEKRREYLTGFHK-------RKVERKKAAIEEIKQRLKEEQR 58
++K++ + RR R + +EE+R + L K RK K E+ +Q +E++R
Sbjct: 634 RRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQER 693
Query: 59 KLREERHQEYLKMLAEREEALEEADELDR 87
+ +E R QE + ER E + E +R
Sbjct: 694 REQERREQE--RREQERREQERQLAEQER 720
Score = 32.7 bits (73), Expect = 0.24
Identities = 22/87 (25%), Positives = 41/87 (47%)
Query: 14 RRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLREERHQEYLKMLA 73
R RL +R E + K+++E+K A I+E ++ KEE+ + + + K +
Sbjct: 570 REERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKME 629
Query: 74 EREEALEEADELDRLVTAKTESVQYDH 100
E E ++ +E RL + E + H
Sbjct: 630 EVEARRKQEEEARRLRWLQQEEEERRH 656
>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
Length = 3907
Score = 39.3 bits (90), Expect = 0.003
Identities = 25/87 (28%), Positives = 47/87 (54%), Gaps = 2/87 (2%)
Query: 12 DDRRPRLVLSFDEEKRR-EYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLREERHQEYLK 70
+D R LV + E ++ E L H R++ER++ E++++ +K R+L + +
Sbjct: 1588 EDMRQELVRQYQEHQQATELLRQAHMRQMERQREDQEQLQEEIKRLNRQLAQRSSIDNEN 1647
Query: 71 MLAEREEA-LEEADELDRLVTAKTESV 96
+++ERE LEE + L +L A E +
Sbjct: 1648 LVSERERVLLEELEALKQLSLAGREKL 1674
Score = 33.9 bits (76), Expect = 0.11
Identities = 27/113 (23%), Positives = 55/113 (48%), Gaps = 5/113 (4%)
Query: 4 NKKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLREE 63
N+ +K D + R + D + R+ L + E +K + E++ ++++ QR+L E+
Sbjct: 3364 NETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKK-MHELQSKVEDLQRQLEEK 3422
Query: 64 RHQEY-LKMLAEREEALE---EADELDRLVTAKTESVQYDHPNHTVTVTTISD 112
R Q Y L + +R + + + EL+R ++ + Y + N T + SD
Sbjct: 3423 RQQVYKLDLEGQRLQGIMQEFQKQELEREEKRESRRILYQNLNEPTTWSLTSD 3475
Score = 30.8 bits (68), Expect = 0.89
Identities = 41/189 (21%), Positives = 84/189 (44%), Gaps = 22/189 (11%)
Query: 5 KKKKRDGDDRRPRLVLSFDEEKRREY-------LTGFHKRKVERKKAAIEEIKQRLKEEQ 57
+KKK D + +SF +EK + Y + +K +++ K+ IEE+ ++ EE+
Sbjct: 288 QKKKEDFT-----MQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEELNTKIIEEE 342
Query: 58 RKLRE--ERHQEYLKMLAE-REEALEEADELDRLVTAKTESVQYDHPNHTVTVTTISDLD 114
+K E ++ K+L E +E+ +++ E+ + T S Q + + + ++
Sbjct: 343 KKTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVE 402
Query: 115 LSGARLLGLTPPEGGAGDRSEEEASSTEKPTKALPRKSRDPLLSQRISSLTASL---HAH 171
R + E R E+E T++ + L R D + Q+I + L H
Sbjct: 403 ELQKRNHKDSQFETDIVQRMEQE---TQRKLEQL-RAELDEMYGQQIVQMKQELIRQHMA 458
Query: 172 SRKKVKRKH 180
+++K +H
Sbjct: 459 QMEEMKTRH 467
>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
Length = 3899
Score = 39.3 bits (90), Expect = 0.003
Identities = 25/87 (28%), Positives = 47/87 (54%), Gaps = 2/87 (2%)
Query: 12 DDRRPRLVLSFDEEKRR-EYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLREERHQEYLK 70
+D R LV + E ++ E L H R++ER++ E++++ +K R+L + +
Sbjct: 1588 EDMRQELVRQYQEHQQATELLRQAHMRQMERQREDQEQLQEEIKRLNRQLAQRSSIDNEN 1647
Query: 71 MLAEREEA-LEEADELDRLVTAKTESV 96
+++ERE LEE + L +L A E +
Sbjct: 1648 LVSERERVLLEELEALKQLSLAGREKL 1674
Score = 33.9 bits (76), Expect = 0.11
Identities = 27/113 (23%), Positives = 55/113 (48%), Gaps = 5/113 (4%)
Query: 4 NKKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLREE 63
N+ +K D + R + D + R+ L + E +K + E++ ++++ QR+L E+
Sbjct: 3356 NETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKK-MHELQSKVEDLQRQLEEK 3414
Query: 64 RHQEY-LKMLAEREEALE---EADELDRLVTAKTESVQYDHPNHTVTVTTISD 112
R Q Y L + +R + + + EL+R ++ + Y + N T + SD
Sbjct: 3415 RQQVYKLDLEGQRLQGIMQEFQKQELEREEKRESRRILYQNLNEPTTWSLTSD 3467
Score = 30.8 bits (68), Expect = 0.89
Identities = 41/189 (21%), Positives = 84/189 (44%), Gaps = 22/189 (11%)
Query: 5 KKKKRDGDDRRPRLVLSFDEEKRREY-------LTGFHKRKVERKKAAIEEIKQRLKEEQ 57
+KKK D + +SF +EK + Y + +K +++ K+ IEE+ ++ EE+
Sbjct: 288 QKKKEDFT-----MQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEELNTKIIEEE 342
Query: 58 RKLRE--ERHQEYLKMLAE-REEALEEADELDRLVTAKTESVQYDHPNHTVTVTTISDLD 114
+K E ++ K+L E +E+ +++ E+ + T S Q + + + ++
Sbjct: 343 KKTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVE 402
Query: 115 LSGARLLGLTPPEGGAGDRSEEEASSTEKPTKALPRKSRDPLLSQRISSLTASL---HAH 171
R + E R E+E T++ + L R D + Q+I + L H
Sbjct: 403 ELQKRNHKDSQFETDIVQRMEQE---TQRKLEQL-RAELDEMYGQQIVQMKQELIRQHMA 458
Query: 172 SRKKVKRKH 180
+++K +H
Sbjct: 459 QMEEMKTRH 467
>gi|115648142 centrosomal protein 164kDa [Homo sapiens]
Length = 1460
Score = 39.3 bits (90), Expect = 0.003
Identities = 43/194 (22%), Positives = 89/194 (45%), Gaps = 12/194 (6%)
Query: 25 EKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLREERHQEYLKMLAEREEALEEADE 84
++ E + H++K + + E +++ ++EE+ ++REE Q L L + ++ +ADE
Sbjct: 627 QEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQR-LSWLRAQVQSSTQADE 685
Query: 85 LDRLVTAKTESVQ-YDHPNHTVTVTTISDLDLSGARLLGLTPPEGGAGDRSEEEASSTEK 143
D++ + S+Q + + L+ ++L E A ++SE+ A + K
Sbjct: 686 -DQIRAEQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAK 744
Query: 144 PTKALPRKSRDPLLSQRISSLTASLHAHSRK------KVKRKHPRRAQD-SKKPPRAPRT 196
KAL ++ R+ L +R ++ HS + ++ KH KK A +
Sbjct: 745 -EKAL-QQLREQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQK 802
Query: 197 SKAQRRRLTGKARH 210
+AQ ++ G+ H
Sbjct: 803 EEAQLQKCLGQVEH 816
Score = 30.0 bits (66), Expect = 1.5
Identities = 20/61 (32%), Positives = 33/61 (54%), Gaps = 3/61 (4%)
Query: 23 DEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLREE---RHQEYLKMLAEREEAL 79
+E K+R L G ++ER + A E + +++EQ K E+ RH+E + L + E L
Sbjct: 872 EERKQRAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDL 931
Query: 80 E 80
E
Sbjct: 932 E 932
>gi|150378449 X-ray radiation resistance associated 1 [Homo sapiens]
Length = 792
Score = 39.3 bits (90), Expect = 0.003
Identities = 51/205 (24%), Positives = 87/205 (42%), Gaps = 30/205 (14%)
Query: 16 PRLVLSFDEEK------RREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLREERHQEYL 69
P L+ SF +E+ RR+ + H + RK++ ++K + + ++ H
Sbjct: 416 PPLLKSFLQERLGIHLIRRKIVKPKHHVLMSRKESW--KVKSEIPKVPKQPLVLHHPRMT 473
Query: 70 KMLAEREEALE-EADELDRLVTAKTESVQYDHPNHTVTVTTISDLDLSGARLLGLTPPEG 128
+ ++ LE EA+ + L T K+ SV+ + P + S + L P
Sbjct: 474 TTKSPSKDMLEPEAELAEDLPTTKSTSVESEMPTEN-----LEGHSPSCRTFVPLPPICS 528
Query: 129 GAGDRSEEEAS---------STEKPTKALPRKSRDPLLSQRISSLTASLHAHSRKKVKRK 179
+ SEE S S E+P+ KS + + ++S L +S+ ++K K
Sbjct: 529 NSTVHSEETLSHLSDTTVRLSPERPSDE-DSKSTESIFLTQVSELPSSVIHKDDLELKEK 587
Query: 180 HPRRAQDSKKPPRAPRTSKAQRRRL 204
D KKPP APR K RR+L
Sbjct: 588 ------DQKKPPTAPREVKGTRRKL 606
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 38.9 bits (89), Expect = 0.003
Identities = 28/96 (29%), Positives = 48/96 (50%), Gaps = 5/96 (5%)
Query: 2 GRNKKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLR 61
G+ K+K+++ + + + + EKR+E KRK +RKK EE ++ +EE+ + +
Sbjct: 27 GKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEK 86
Query: 62 EERHQE-----YLKMLAEREEALEEADELDRLVTAK 92
EE +E K R+E EE + R T K
Sbjct: 87 EEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKK 122
Score = 38.5 bits (88), Expect = 0.004
Identities = 26/85 (30%), Positives = 46/85 (54%), Gaps = 5/85 (5%)
Query: 3 RNKKKKRDGDDRRPRLVLSFDEE---KRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRK 59
+ KKKK++ ++ +EE KR+E KRK + KK +E ++R ++E+ +
Sbjct: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRK--EKRKEKEKKKKTKETEKRKEKEEEE 59
Query: 60 LREERHQEYLKMLAEREEALEEADE 84
+ +R ++ K EREE EE +E
Sbjct: 60 KKRKRKRKKKKEEEEREEEEEEEEE 84
Score = 32.3 bits (72), Expect = 0.31
Identities = 16/61 (26%), Positives = 34/61 (55%)
Query: 3 RNKKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLRE 62
+ K+KK+ ++ R +EEK E +RK ++K+ EE +++ K+ +RK ++
Sbjct: 63 KRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKK 122
Query: 63 E 63
+
Sbjct: 123 K 123
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 38.9 bits (89), Expect = 0.003
Identities = 51/222 (22%), Positives = 89/222 (40%), Gaps = 16/222 (7%)
Query: 3 RNKKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLRE 62
R ++ G++ RL + + + L KR+VE + +EE+ + E++++ +
Sbjct: 30 RGERPDYKGEEELRRLEAALVKRPNPDILDHERKRRVELRCLELEEMMEEQGYEEQQI-Q 88
Query: 63 ERHQEYLKMLAEREEALEEADELDRLVTAKTESVQYDHPNHTV-----TVTTISDLDLSG 117
E+ + ML E++ +E A TE+ Q N ISD + G
Sbjct: 89 EKVATFRLMLLEKDVNPGGKEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDG 148
Query: 118 --------ARLLGLTPPEGGAGDRSEEEASSTEKPTKALPRKSRDPLLSQRISSLTASLH 169
AR PE E+SS+ PT +K + +R S ++S
Sbjct: 149 SSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRR--SESSSPR 206
Query: 170 AHSRKKVKRKHPRRAQDSKKPPRAPRTSKAQRRRLTGKARHS 211
+K K+K R +SKK T K++R+ K + S
Sbjct: 207 RERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRS 248
Score = 30.0 bits (66), Expect = 1.5
Identities = 24/94 (25%), Positives = 39/94 (41%), Gaps = 6/94 (6%)
Query: 124 TPPEGGAGDRSE------EEASSTEKPTKALPRKSRDPLLSQRISSLTASLHAHSRKKVK 177
TPP RS + + S P +SR PL+S+R S S + R + +
Sbjct: 1844 TPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSR 1903
Query: 178 RKHPRRAQDSKKPPRAPRTSKAQRRRLTGKARHS 211
RR S+ P + R S+++ +T + S
Sbjct: 1904 TSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRS 1937
Score = 28.1 bits (61), Expect = 5.8
Identities = 22/80 (27%), Positives = 31/80 (38%), Gaps = 1/80 (1%)
Query: 124 TPPEGGAGDRSEEEASSTEKPTKALPRKSRDPLLSQRISSLTASLHAHSRKKVKRKHPRR 183
TPP S+ +A S P ++ S P + S + + KVK P R
Sbjct: 792 TPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPR 851
Query: 184 AQDSKKPPRAPRTSKAQRRR 203
Q S P+A S +RR
Sbjct: 852 -QGSITSPQANEQSVTPQRR 870
Score = 28.1 bits (61), Expect = 5.8
Identities = 23/90 (25%), Positives = 36/90 (40%), Gaps = 6/90 (6%)
Query: 104 TVTVTTISDLDLSGARLLGLTPPEGGAGDRSEEEASSTEKPTKALPRKSRDPLLSQRISS 163
TV T + SG+ P +RSE ++S K K+R PL + S
Sbjct: 1527 TVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKA------KTRTPLRQRSRSG 1580
Query: 164 LTASLHAHSRKKVKRKHPRRAQDSKKPPRA 193
+ + + SR +R + + K PRA
Sbjct: 1581 SSPEVDSKSRLSPRRSRSGSSPEVKDKPRA 1610
Score = 27.3 bits (59), Expect = 9.9
Identities = 22/77 (28%), Positives = 33/77 (42%), Gaps = 9/77 (11%)
Query: 133 RSEEEASSTEKPTKALPRKSRDPLLSQRISSLTASLHAHSRKKVKRKHP------RRAQD 186
RS +SS E ++ PR R P +S S A SR++ P RR +
Sbjct: 1706 RSRSASSSPETRSRTPPRHRRSPSVS---SPEPAEKSRSSRRRRSASSPRTKTTSRRGRS 1762
Query: 187 SKKPPRAPRTSKAQRRR 203
PR + S+++ RR
Sbjct: 1763 PSPKPRGLQRSRSRSRR 1779
>gi|149363664 septin 8 isoform d [Homo sapiens]
Length = 369
Score = 38.5 bits (88), Expect = 0.004
Identities = 27/97 (27%), Positives = 51/97 (52%), Gaps = 10/97 (10%)
Query: 10 DGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQ---RLKEEQRKLREE--- 63
DGD + L ++ E KR+E+L+ +++ E ++ + ++K+ LKE++R+L E+
Sbjct: 254 DGDSQPFSLQETY-EAKRKEFLSELQRKEEEMRQMFVNKVKETELELKEKERELHEKFEH 312
Query: 64 ---RHQEYLKMLAEREEALEEADELDRLVTAKTESVQ 97
HQE + + E+ LEE A E++Q
Sbjct: 313 LKRVHQEEKRKVEEKRRELEEETNAFNRRKAAVEALQ 349
>gi|149363638 septin 8 isoform c [Homo sapiens]
Length = 442
Score = 38.5 bits (88), Expect = 0.004
Identities = 27/97 (27%), Positives = 51/97 (52%), Gaps = 10/97 (10%)
Query: 10 DGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQ---RLKEEQRKLREE--- 63
DGD + L ++ E KR+E+L+ +++ E ++ + ++K+ LKE++R+L E+
Sbjct: 314 DGDSQPFSLQETY-EAKRKEFLSELQRKEEEMRQMFVNKVKETELELKEKERELHEKFEH 372
Query: 64 ---RHQEYLKMLAEREEALEEADELDRLVTAKTESVQ 97
HQE + + E+ LEE A E++Q
Sbjct: 373 LKRVHQEEKRKVEEKRRELEEETNAFNRRKAAVEALQ 409
>gi|149363689 septin 8 isoform a [Homo sapiens]
Length = 483
Score = 38.5 bits (88), Expect = 0.004
Identities = 27/97 (27%), Positives = 51/97 (52%), Gaps = 10/97 (10%)
Query: 10 DGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQ---RLKEEQRKLREE--- 63
DGD + L ++ E KR+E+L+ +++ E ++ + ++K+ LKE++R+L E+
Sbjct: 314 DGDSQPFSLQETY-EAKRKEFLSELQRKEEEMRQMFVNKVKETELELKEKERELHEKFEH 372
Query: 64 ---RHQEYLKMLAEREEALEEADELDRLVTAKTESVQ 97
HQE + + E+ LEE A E++Q
Sbjct: 373 LKRVHQEEKRKVEEKRRELEEETNAFNRRKAAVEALQ 409
>gi|149363661 septin 8 isoform b [Homo sapiens]
Length = 429
Score = 38.5 bits (88), Expect = 0.004
Identities = 27/97 (27%), Positives = 51/97 (52%), Gaps = 10/97 (10%)
Query: 10 DGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQ---RLKEEQRKLREE--- 63
DGD + L ++ E KR+E+L+ +++ E ++ + ++K+ LKE++R+L E+
Sbjct: 314 DGDSQPFSLQETY-EAKRKEFLSELQRKEEEMRQMFVNKVKETELELKEKERELHEKFEH 372
Query: 64 ---RHQEYLKMLAEREEALEEADELDRLVTAKTESVQ 97
HQE + + E+ LEE A E++Q
Sbjct: 373 LKRVHQEEKRKVEEKRRELEEETNAFNRRKAAVEALQ 409
>gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo
sapiens]
Length = 1272
Score = 38.5 bits (88), Expect = 0.004
Identities = 31/97 (31%), Positives = 48/97 (49%), Gaps = 15/97 (15%)
Query: 6 KKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLREE-- 63
KKKR DD+R + E+K R K+K E K A EE K++ +EE++K +EE
Sbjct: 56 KKKRLEDDKRKK------EDKER-------KKKDEEKVKAEEESKKKEEEEKKKHQEEER 102
Query: 64 RHQEYLKMLAEREEALEEADELDRLVTAKTESVQYDH 100
+ QE + EEA + E + + E+ + H
Sbjct: 103 KKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHH 139
Score = 32.3 bits (72), Expect = 0.31
Identities = 26/95 (27%), Positives = 48/95 (50%), Gaps = 14/95 (14%)
Query: 5 KKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLREE- 63
K+ + +D++ RL +++KR+ K ERKK E++K +E ++K EE
Sbjct: 47 KEVSKAPEDKKKRL----EDDKRK-------KEDKERKKKDEEKVKAE-EESKKKEEEEK 94
Query: 64 -RHQEYLKMLAEREEALEEADELDRLVTAKTESVQ 97
+HQE + E + ++ +E + K ES+Q
Sbjct: 95 KKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQ 129
Score = 30.0 bits (66), Expect = 1.5
Identities = 17/76 (22%), Positives = 34/76 (44%), Gaps = 2/76 (2%)
Query: 28 REYLTGF--HKRKVERKKAAIEEIKQRLKEEQRKLREERHQEYLKMLAEREEALEEADEL 85
+EY T H ++ R+ E +R+ + +L E+RH++Y + ++ L + L
Sbjct: 357 KEYFTSLTKHLKRDHRELQNTERQNRRILHSKGELSEDRHKQYEEFAMSYQKLLANSQSL 416
Query: 86 DRLVTAKTESVQYDHP 101
L+ + D P
Sbjct: 417 ADLLDENMPDLPQDKP 432
Score = 27.3 bits (59), Expect = 9.9
Identities = 25/82 (30%), Positives = 44/82 (53%), Gaps = 13/82 (15%)
Query: 7 KKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKV----ERKKAAIEEIKQRLKEEQRKLRE 62
K++D +RR V S + K LT K++V E KK +E+ K++ ++++RK ++
Sbjct: 21 KEKDCSERRT--VSSKERPKDDIKLTA--KKEVSKAPEDKKKRLEDDKRKKEDKERKKKD 76
Query: 63 ERHQEYLKMLAEREEALEEADE 84
E K+ AE E +E +E
Sbjct: 77 EE-----KVKAEEESKKKEEEE 93
>gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo
sapiens]
Length = 1272
Score = 38.5 bits (88), Expect = 0.004
Identities = 31/97 (31%), Positives = 48/97 (49%), Gaps = 15/97 (15%)
Query: 6 KKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLREE-- 63
KKKR DD+R + E+K R K+K E K A EE K++ +EE++K +EE
Sbjct: 56 KKKRLEDDKRKK------EDKER-------KKKDEEKVKAEEESKKKEEEEKKKHQEEER 102
Query: 64 RHQEYLKMLAEREEALEEADELDRLVTAKTESVQYDH 100
+ QE + EEA + E + + E+ + H
Sbjct: 103 KKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHH 139
Score = 32.3 bits (72), Expect = 0.31
Identities = 26/95 (27%), Positives = 48/95 (50%), Gaps = 14/95 (14%)
Query: 5 KKKKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLREE- 63
K+ + +D++ RL +++KR+ K ERKK E++K +E ++K EE
Sbjct: 47 KEVSKAPEDKKKRL----EDDKRK-------KEDKERKKKDEEKVKAE-EESKKKEEEEK 94
Query: 64 -RHQEYLKMLAEREEALEEADELDRLVTAKTESVQ 97
+HQE + E + ++ +E + K ES+Q
Sbjct: 95 KKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQ 129
Score = 30.0 bits (66), Expect = 1.5
Identities = 17/76 (22%), Positives = 34/76 (44%), Gaps = 2/76 (2%)
Query: 28 REYLTGF--HKRKVERKKAAIEEIKQRLKEEQRKLREERHQEYLKMLAEREEALEEADEL 85
+EY T H ++ R+ E +R+ + +L E+RH++Y + ++ L + L
Sbjct: 357 KEYFTSLTKHLKRDHRELQNTERQNRRILHSKGELSEDRHKQYEEFAMSYQKLLANSQSL 416
Query: 86 DRLVTAKTESVQYDHP 101
L+ + D P
Sbjct: 417 ADLLDENMPDLPQDKP 432
Score = 27.3 bits (59), Expect = 9.9
Identities = 25/82 (30%), Positives = 44/82 (53%), Gaps = 13/82 (15%)
Query: 7 KKRDGDDRRPRLVLSFDEEKRREYLTGFHKRKV----ERKKAAIEEIKQRLKEEQRKLRE 62
K++D +RR V S + K LT K++V E KK +E+ K++ ++++RK ++
Sbjct: 21 KEKDCSERRT--VSSKERPKDDIKLTA--KKEVSKAPEDKKKRLEDDKRKKEDKERKKKD 76
Query: 63 ERHQEYLKMLAEREEALEEADE 84
E K+ AE E +E +E
Sbjct: 77 EE-----KVKAEEESKKKEEEE 93
>gi|4506467 radixin [Homo sapiens]
Length = 583
Score = 38.1 bits (87), Expect = 0.006
Identities = 27/79 (34%), Positives = 47/79 (59%), Gaps = 9/79 (11%)
Query: 23 DEEKRREYLTGFHKRKVERKKAAIEEIKQRLK--EEQ----RKLREERHQEYLKMLAERE 76
+ EK++ + K ++ER+K EE+ +RLK EEQ +K EE+ ++ L++ ER+
Sbjct: 324 ENEKKKREIAEKEKERIEREK---EELMERLKQIEEQTIKAQKELEEQTRKALELDQERK 380
Query: 77 EALEEADELDRLVTAKTES 95
A EEA+ L++ A E+
Sbjct: 381 RAKEEAERLEKERRAAEEA 399
Score = 31.6 bits (70), Expect = 0.52
Identities = 20/67 (29%), Positives = 35/67 (52%), Gaps = 3/67 (4%)
Query: 24 EEKRREYLTGFHKRKVERKKAAIEEIKQRLKEEQRKLREERHQ---EYLKMLAEREEALE 80
EEK ++ L ++K+ E+ K+R++ E+ +L E Q + +K E EE
Sbjct: 311 EEKHQKQLERAQLENEKKKREIAEKEKERIEREKEELMERLKQIEEQTIKAQKELEEQTR 370
Query: 81 EADELDR 87
+A ELD+
Sbjct: 371 KALELDQ 377
Score = 28.1 bits (61), Expect = 5.8
Identities = 24/99 (24%), Positives = 47/99 (47%), Gaps = 8/99 (8%)
Query: 4 NKKKKRDGDDRRPRLVLSFDEE-----KRREYLTGFHKRKVE---RKKAAIEEIKQRLKE 55
N+KKKR+ ++ + EE K+ E T ++++E RK +++ ++R KE
Sbjct: 325 NEKKKREIAEKEKERIEREKEELMERLKQIEEQTIKAQKELEEQTRKALELDQERKRAKE 384
Query: 56 EQRKLREERHQEYLKMLAEREEALEEADELDRLVTAKTE 94
E +L +ER A ++A ++ ++L E
Sbjct: 385 EAERLEKERRAAEEAKSAIAKQAADQMKNQEQLAAELAE 423
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.127 0.343
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,666,216
Number of Sequences: 37866
Number of extensions: 402749
Number of successful extensions: 7419
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 324
Number of HSP's successfully gapped in prelim test: 529
Number of HSP's that attempted gapping in prelim test: 3978
Number of HSP's gapped (non-prelim): 2827
length of query: 213
length of database: 18,247,518
effective HSP length: 98
effective length of query: 115
effective length of database: 14,536,650
effective search space: 1671714750
effective search space used: 1671714750
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.