Guide to the Human Genome
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Search of human proteins with 109240538

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|109240538 polycomb group ring finger 1 [Homo sapiens]
         (259 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|109240538 polycomb group ring finger 1 [Homo sapiens]              534   e-152
gi|31742478 ring finger protein 3 [Homo sapiens]                      177   8e-45
gi|27883842 BMI1 polycomb ring finger oncogene [Homo sapiens]         170   1e-42
gi|6005964 ring finger protein 110 [Homo sapiens]                     165   3e-41
gi|58761530 polycomb group ring finger 6 isoform a [Homo sapiens]     155   3e-38
gi|33300663 polycomb group ring finger 5 [Homo sapiens]               145   3e-35
gi|37655165 polycomb group ring finger 6 isoform b [Homo sapiens]      97   2e-20
gi|197245452 ring finger protein 24 isoform 2 [Homo sapiens]           52   4e-07
gi|197245450 ring finger protein 24 isoform 1 [Homo sapiens]           52   4e-07
gi|6857791 ring finger protein 24 isoform 1 [Homo sapiens]             52   4e-07
gi|51479192 ring finger protein 1 [Homo sapiens]                       52   7e-07
gi|6005747 ring finger protein 2 [Homo sapiens]                        50   1e-06
gi|14550405 postreplication repair protein hRAD18p [Homo sapiens]      50   2e-06
gi|4504867 ring finger protein 8 isoform 1 [Homo sapiens]              50   3e-06
gi|30425428 deltex homolog 3 [Homo sapiens]                            50   3e-06
gi|87080813 LON peptidase N-terminal domain and ring finger 1 [H...    50   3e-06
gi|148528975 LON peptidase N-terminal domain and ring finger 2 [...    49   3e-06
gi|239048909 checkpoint with forkhead and ring finger domains is...    48   7e-06
gi|239048905 checkpoint with forkhead and ring finger domains is...    48   7e-06
gi|239048862 checkpoint with forkhead and ring finger domains is...    48   7e-06
gi|239048792 checkpoint with forkhead and ring finger domains is...    48   7e-06
gi|239048907 checkpoint with forkhead and ring finger domains is...    48   7e-06
gi|239755486 PREDICTED: tripartite motif-containing protein 64C-...    47   2e-05
gi|239755484 PREDICTED: tripartite motif-containing protein 64C-...    47   2e-05
gi|239750044 PREDICTED: tripartite motif-containing protein 64C-...    47   2e-05
gi|239750042 PREDICTED: tripartite motif-containing protein 64C-...    47   2e-05
gi|239744355 PREDICTED: tripartite motif-containing protein 64C-...    47   2e-05
gi|239744353 PREDICTED: tripartite motif-containing protein 64C-...    47   2e-05
gi|34878777 ring finger protein 20 [Homo sapiens]                      45   6e-05
gi|73747840 LON peptidase N-terminal domain and ring finger 3 is...    45   6e-05

>gi|109240538 polycomb group ring finger 1 [Homo sapiens]
          Length = 259

 Score =  534 bits (1376), Expect = e-152
 Identities = 259/259 (100%), Positives = 259/259 (100%)

Query: 1   MASPQGGQIAIAMRLRNQLQSVYKMDPLRNEEEVRVKIKDLNEHIVCCLCAGYFVDATTI 60
           MASPQGGQIAIAMRLRNQLQSVYKMDPLRNEEEVRVKIKDLNEHIVCCLCAGYFVDATTI
Sbjct: 1   MASPQGGQIAIAMRLRNQLQSVYKMDPLRNEEEVRVKIKDLNEHIVCCLCAGYFVDATTI 60

Query: 61  TECLHTFCKSCIVKYLQTSKYCPMCNIKIHETQPLLNLKLDRVMQDIVYKLVPGLQDSEE 120
           TECLHTFCKSCIVKYLQTSKYCPMCNIKIHETQPLLNLKLDRVMQDIVYKLVPGLQDSEE
Sbjct: 61  TECLHTFCKSCIVKYLQTSKYCPMCNIKIHETQPLLNLKLDRVMQDIVYKLVPGLQDSEE 120

Query: 121 KRIREFYQSRGLDRVTQPTGEEPALSNLGLPFSSFDHSKAHYYRYDEQLNLCLERLSSGK 180
           KRIREFYQSRGLDRVTQPTGEEPALSNLGLPFSSFDHSKAHYYRYDEQLNLCLERLSSGK
Sbjct: 121 KRIREFYQSRGLDRVTQPTGEEPALSNLGLPFSSFDHSKAHYYRYDEQLNLCLERLSSGK 180

Query: 181 DKNKSVLQNKYVRCSVRAEVRHLRRVLCHRLMLNPQHVQLLFDNEVLPDHMTMKQIWLSR 240
           DKNKSVLQNKYVRCSVRAEVRHLRRVLCHRLMLNPQHVQLLFDNEVLPDHMTMKQIWLSR
Sbjct: 181 DKNKSVLQNKYVRCSVRAEVRHLRRVLCHRLMLNPQHVQLLFDNEVLPDHMTMKQIWLSR 240

Query: 241 WFGKPSPLLLQYSVKEKRR 259
           WFGKPSPLLLQYSVKEKRR
Sbjct: 241 WFGKPSPLLLQYSVKEKRR 259


>gi|31742478 ring finger protein 3 [Homo sapiens]
          Length = 242

 Score =  177 bits (449), Expect = 8e-45
 Identities = 97/238 (40%), Positives = 142/238 (59%), Gaps = 21/238 (8%)

Query: 35  RVKIKDLNEHIVCCLCAGYFVDATTITECLHTFCKSCIVKYLQTSKYCPMCNIKIHETQP 94
           ++K+ D+N HI C LC+GY +DATT+TECLHTFC+SC+VKYL+ +  CP C I IH++ P
Sbjct: 5   KIKLWDINAHITCRLCSGYLIDATTVTECLHTFCRSCLVKYLEENNTCPTCRIVIHQSHP 64

Query: 95  LLNLKLDRVMQDIVYKLVPGLQDSEEKRIREFYQSRGLDRVTQPTGEEPAL-----SNLG 149
           L  +  DR MQDIVYKLVPGLQ++E ++ REFY   G++      GE  +      S+  
Sbjct: 65  LQYIGHDRTMQDIVYKLVPGLQEAEMRKQREFYHKLGMEVPGDIKGETCSAKQHLDSHRN 124

Query: 150 LPFSSFDHSKAH-----------YYRYDEQLNLCLERLSSGKDKNKSVLQNKYVRCSVRA 198
               + D S              Y+R DEQ+++CLE  SS        L+ K++RCS +A
Sbjct: 125 GETKADDSSNKEAAEEKPEEDNDYHRSDEQVSICLECNSS----KLRGLKRKWIRCSAQA 180

Query: 199 EVRHLRRVLCHRLMLNP-QHVQLLFDNEVLPDHMTMKQIWLSRWFGKPSPLLLQYSVK 255
            V HL++ +  +L L+    + +L + E+L    T+K + ++RW  K +PLLL Y  K
Sbjct: 181 TVLHLKKFIAKKLNLSSFNELDILCNEEILGKDHTLKFVVVTRWRFKKAPLLLHYRPK 238


>gi|27883842 BMI1 polycomb ring finger oncogene [Homo sapiens]
          Length = 326

 Score =  170 bits (431), Expect = 1e-42
 Identities = 87/224 (38%), Positives = 141/224 (62%), Gaps = 4/224 (1%)

Query: 35  RVKIKDLNEHIVCCLCAGYFVDATTITECLHTFCKSCIVKYLQTSKYCPMCNIKIHETQP 94
           R+KI +LN H++C LC GYF+DATTI ECLH+FCK+CIV+YL+TSKYCP+C++++H+T+P
Sbjct: 6   RIKITELNPHLMCVLCGGYFIDATTIIECLHSFCKTCIVRYLETSKYCPICDVQVHKTRP 65

Query: 95  LLNLKLDRVMQDIVYKLVPGLQDSEEKRIREFYQSR-GLDRVTQPTGEEPALSNLGLPFS 153
           LLN++ D+ +QDIVYKLVPGL  +E KR R+FY +    D       +   +++      
Sbjct: 66  LLNIRSDKTLQDIVYKLVPGLFKNEMKRRRDFYAAHPSADAANGSNEDRGEVADEDKRII 125

Query: 154 SFDHSKAHYYRYDEQLNLCLERLSSGKDKNKSVLQNK-YVRCSVRAEVRHLRRVLCHRLM 212
           + D   +    + +Q N    +++  K+K+K  + +K Y+RC     V HLR+ L  ++ 
Sbjct: 126 TDDEIISLSIEFFDQ-NRLDRKVNKDKEKSKEEVNDKRYLRCPAAMTVMHLRKFLRSKMD 184

Query: 213 L-NPQHVQLLFDNEVLPDHMTMKQIWLSRWFGKPSPLLLQYSVK 255
           + N   + ++++ E L D+ T+  I     + +  PL L+Y V+
Sbjct: 185 IPNTFQIDVMYEEEPLKDYYTLMDIAYIYTWRRNGPLPLKYRVR 228


>gi|6005964 ring finger protein 110 [Homo sapiens]
          Length = 344

 Score =  165 bits (418), Expect = 3e-41
 Identities = 88/234 (37%), Positives = 143/234 (61%), Gaps = 22/234 (9%)

Query: 35  RVKIKDLNEHIVCCLCAGYFVDATTITECLHTFCKSCIVKYLQTSKYCPMCNIKIHETQP 94
           R+KI +LN H++C LC GYF+DATTI ECLH+FCK+CIV+YL+T+KYCPMC++++H+T+P
Sbjct: 6   RIKITELNPHLMCALCGGYFIDATTIVECLHSFCKTCIVRYLETNKYCPMCDVQVHKTRP 65

Query: 95  LLNLKLDRVMQDIVYKLVPGLQDSEEKRIREFYQSRGLDRVTQPTGEEPALSNLGLPFSS 154
           LL+++ D+ +QDIVYKLVPGL   E KR R+FY +  L  V   + E+            
Sbjct: 66  LLSIRSDKTLQDIVYKLVPGLFKDEMKRRRDFYAAYPLTEVPNGSNEDRG--------EV 117

Query: 155 FDHSKAHYYRYDEQLNLCLERLSSGKDKN--KSVLQN----------KYVRCSVRAEVRH 202
            +  K      DE ++L +E     +D++  K  L+N          +++RC     V H
Sbjct: 118 LEQEKG-ALSDDEIVSLSIEFYEGARDRDEKKGPLENGDGDKEKTGVRFLRCPAAMTVMH 176

Query: 203 LRRVLCHRLMLNPQH-VQLLFDNEVLPDHMTMKQIWLSRWFGKPSPLLLQYSVK 255
           L + L +++ +  ++ V++L+++E L ++ T+  I     + +  PL L+Y V+
Sbjct: 177 LAKFLRNKMDVPSKYKVEVLYEDEPLKEYYTLMDIAYIYPWRRNGPLPLKYRVQ 230


>gi|58761530 polycomb group ring finger 6 isoform a [Homo sapiens]
          Length = 350

 Score =  155 bits (392), Expect = 3e-38
 Identities = 81/211 (38%), Positives = 130/211 (61%), Gaps = 9/211 (4%)

Query: 30  NEEEVRVKIKDLNEHIVCCLCAGYFVDATTITECLHTFCKSCIVKYLQTSKYCPMCNIKI 89
           +EEE  + + +L  +I+C +C GY +DATTITECLHTFCKSCIV++   S  CP CNI +
Sbjct: 117 DEEERLINLSELTPYILCSICKGYLIDATTITECLHTFCKSCIVRHFYYSNRCPKCNIVV 176

Query: 90  HETQPLLNLKLDRVMQDIVYKLVPGLQDSEEKRIREFYQSRGLDRVTQPTGEEPALSNLG 149
           H+TQPL N++LDR +QDIVYKLV  L++ E+K++ +FY+ RGL+ V +P   +P  S+ G
Sbjct: 177 HQTQPLYNIRLDRQLQDIVYKLVINLEEREKKQMHDFYKERGLE-VPKPAVPQPVPSSKG 235

Query: 150 LPFSSFDHSKAHYYRYDEQLNLCLERLSSGKDKNK---SVLQNKYVRCSVRAEVRHLRRV 206
                 +      +R   +L++ L     G ++       L+ K+VR S  A + H+ + 
Sbjct: 236 RSKKVLE----SVFRIPPELDMSLLLEFIGANEGTGHFKPLEKKFVRVSGEATIGHVEKF 291

Query: 207 LCHRLMLNPQ-HVQLLFDNEVLPDHMTMKQI 236
           L  ++ L+P   V ++  + +L  + T+++I
Sbjct: 292 LRRKMGLDPACQVDIICGDHLLEQYQTLREI 322


>gi|33300663 polycomb group ring finger 5 [Homo sapiens]
          Length = 256

 Score =  145 bits (366), Expect = 3e-35
 Identities = 75/213 (35%), Positives = 124/213 (58%), Gaps = 15/213 (7%)

Query: 38  IKDLNEHIVCCLCAGYFVDATTITECLHTFCKSCIVKYLQTSKYCPMCNIKIHETQPLLN 97
           +KD N +I C +C GY +  TT+TECLHTFCK+CIV++ + S  CP C  ++HET PL  
Sbjct: 9   VKDFNPYITCYICKGYLIKPTTVTECLHTFCKTCIVQHFEDSNDCPRCGNQVHETNPLEM 68

Query: 98  LKLDRVMQDIVYKLVPGLQDSEEKRIREFY-----QSRGLDRVTQPTGEEPALSNLGLPF 152
           L+LD  +++I++KLVPGL++ E +R  EF+     Q  G D  ++   ++P +   G   
Sbjct: 69  LRLDNTLEEIIFKLVPGLREQELERESEFWKKNKPQENGQDDTSK--ADKPKVDEEG--- 123

Query: 153 SSFDHSKAHYYRYDEQLNLCLERLSSGKDKNKSV---LQNKYVRCSVRAEVRHLRRVLCH 209
              +     Y+R D Q+ +CL+ L +      +V   L  K++RCS R  V  +++ L  
Sbjct: 124 -DENEDDKDYHRSDPQIAICLDCLRNNGQSGDNVVKGLMKKFIRCSTRVTVGTIKKFLSL 182

Query: 210 RLML-NPQHVQLLFDNEVLPDHMTMKQIWLSRW 241
           +L L +   + +L + E++    TM+ I+++RW
Sbjct: 183 KLKLPSSYELDVLCNGEIMGKDHTMEFIYMTRW 215


>gi|37655165 polycomb group ring finger 6 isoform b [Homo sapiens]
          Length = 275

 Score = 96.7 bits (239), Expect = 2e-20
 Identities = 39/69 (56%), Positives = 52/69 (75%)

Query: 30  NEEEVRVKIKDLNEHIVCCLCAGYFVDATTITECLHTFCKSCIVKYLQTSKYCPMCNIKI 89
           +EEE  + + +L  +I+C +C GY +DATTITECLHTFCKSCIV++   S  CP CNI +
Sbjct: 117 DEEERLINLSELTPYILCSICKGYLIDATTITECLHTFCKSCIVRHFYYSNRCPKCNIVV 176

Query: 90  HETQPLLNL 98
           H+TQPL N+
Sbjct: 177 HQTQPLYNI 185



 Score = 29.6 bits (65), Expect = 2.7
 Identities = 14/51 (27%), Positives = 30/51 (58%), Gaps = 1/51 (1%)

Query: 187 LQNKYVRCSVRAEVRHLRRVLCHRLMLNPQ-HVQLLFDNEVLPDHMTMKQI 236
           L+ K+VR S  A + H+ + L  ++ L+P   V ++  + +L  + T+++I
Sbjct: 197 LEKKFVRVSGEATIGHVEKFLRRKMGLDPACQVDIICGDHLLEQYQTLREI 247


>gi|197245452 ring finger protein 24 isoform 2 [Homo sapiens]
          Length = 169

 Score = 52.4 bits (124), Expect = 4e-07
 Identities = 25/71 (35%), Positives = 41/71 (57%), Gaps = 3/71 (4%)

Query: 34  VRVKIKDLNEHIVCCLCAGYFV--DATTITECLHTFCKSCIVKYLQTSKYCPMCNIKIHE 91
           ++ K+K+LN H +C +C   F   D   I  C H F + C++K+L+  K CP+CN+ + +
Sbjct: 86  LKEKVKELNLHELCAVCLEDFKPRDELGICPCKHAFHRKCLIKWLEVRKVCPLCNMPVLQ 145

Query: 92  TQPLLNLKLDR 102
               L+ K DR
Sbjct: 146 LAQ-LHSKQDR 155


>gi|197245450 ring finger protein 24 isoform 1 [Homo sapiens]
          Length = 148

 Score = 52.4 bits (124), Expect = 4e-07
 Identities = 25/71 (35%), Positives = 41/71 (57%), Gaps = 3/71 (4%)

Query: 34  VRVKIKDLNEHIVCCLCAGYFV--DATTITECLHTFCKSCIVKYLQTSKYCPMCNIKIHE 91
           ++ K+K+LN H +C +C   F   D   I  C H F + C++K+L+  K CP+CN+ + +
Sbjct: 65  LKEKVKELNLHELCAVCLEDFKPRDELGICPCKHAFHRKCLIKWLEVRKVCPLCNMPVLQ 124

Query: 92  TQPLLNLKLDR 102
               L+ K DR
Sbjct: 125 LAQ-LHSKQDR 134


>gi|6857791 ring finger protein 24 isoform 1 [Homo sapiens]
          Length = 148

 Score = 52.4 bits (124), Expect = 4e-07
 Identities = 25/71 (35%), Positives = 41/71 (57%), Gaps = 3/71 (4%)

Query: 34  VRVKIKDLNEHIVCCLCAGYFV--DATTITECLHTFCKSCIVKYLQTSKYCPMCNIKIHE 91
           ++ K+K+LN H +C +C   F   D   I  C H F + C++K+L+  K CP+CN+ + +
Sbjct: 65  LKEKVKELNLHELCAVCLEDFKPRDELGICPCKHAFHRKCLIKWLEVRKVCPLCNMPVLQ 124

Query: 92  TQPLLNLKLDR 102
               L+ K DR
Sbjct: 125 LAQ-LHSKQDR 134


>gi|51479192 ring finger protein 1 [Homo sapiens]
          Length = 406

 Score = 51.6 bits (122), Expect = 7e-07
 Identities = 31/117 (26%), Positives = 58/117 (49%), Gaps = 10/117 (8%)

Query: 33  EVRVKIKDLNEHIVCCLCAGYFVDATTITECLHTFCKSCIVKYLQT-SKYCPMCNIKIHE 91
           E+ V  + L+  ++C +C     +  T  ECLH FC  CIV  L++ +K CP C  K+  
Sbjct: 34  EIAVSPRSLHSELMCPICLDMLKNTMTTKECLHRFCSDCIVTALRSGNKECPTCRKKLVS 93

Query: 92  TQPLLNLKLDRVMQDIVYKLVPGLQDSEEKRIREFYQSRGLDRVTQPTGEEPALSNL 148
            +   +L+ D     ++ K+ P  ++ E       +Q R L R+++   ++   S++
Sbjct: 94  KR---SLRPDPNFDALISKIYPSREEYEA------HQDRVLIRLSRLHNQQALSSSI 141


>gi|6005747 ring finger protein 2 [Homo sapiens]
          Length = 336

 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 32/116 (27%), Positives = 57/116 (49%), Gaps = 11/116 (9%)

Query: 33  EVRVKIKDLNEHIVCCLCAGYFVDATTITECLHTFCKSCIVKYLQT-SKYCPMCNIKIHE 91
           E+ V  + L+  ++C +C     +  T  ECLH FC  CI+  L++ +K CP C  K+  
Sbjct: 37  EIVVSPRSLHSELMCPICLDMLKNTMTTKECLHRFCADCIITALRSGNKECPTCRKKLVS 96

Query: 92  TQPLLNLKLDRVMQDIVYKLVPGLQDSEEKRIREFYQSRGLDRVTQPTGEEPALSN 147
            +   +L+ D     ++ K+ P   + E       +Q R L R+ +   ++ ALS+
Sbjct: 97  KR---SLRPDPNFDALISKIYPSRDEYEA------HQERVLARINKHNNQQ-ALSH 142


>gi|14550405 postreplication repair protein hRAD18p [Homo sapiens]
          Length = 495

 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 24/74 (32%), Positives = 42/74 (56%), Gaps = 4/74 (5%)

Query: 38  IKDLNEHIVCCLCAGYFVDATTITECLHTFCKSCIVKYLQTSKYCPMCNIKIHETQPLLN 97
           +K +++ + C +C  YF  A  I +C H +C  CI K+L     CP C + +  T+P  +
Sbjct: 16  MKTIDDLLRCGICFEYFNIAMIIPQCSHNYCSLCIRKFLSYKTQCPTCCVTV--TEP--D 71

Query: 98  LKLDRVMQDIVYKL 111
           LK +R++ ++V  L
Sbjct: 72  LKNNRILDELVKSL 85


>gi|4504867 ring finger protein 8 isoform 1 [Homo sapiens]
          Length = 485

 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 29/96 (30%), Positives = 51/96 (53%), Gaps = 4/96 (4%)

Query: 31  EEEVRVKIKDLNEH-IVCCLCAGYFVDATTITECLHTFCKSCIVKYLQTSKYCPMCNIKI 89
           +EEV   + D+ E+ + C +C+ YF++A T+  C H+FC  CI ++++    CP+C   I
Sbjct: 386 KEEVLSHMNDVLENELQCIICSEYFIEAVTLN-CAHSFCSYCINEWMKRKIECPICRKDI 444

Query: 90  HETQPLLNLKLDRVMQDIVYKLVPGLQDSEEKRIRE 125
                  +L LD  +  +V  L   +++     IRE
Sbjct: 445 --KSKTYSLVLDNCINKMVNNLSSEVKERRIVLIRE 478


>gi|30425428 deltex homolog 3 [Homo sapiens]
          Length = 347

 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 19/51 (37%), Positives = 30/51 (58%)

Query: 35  RVKIKDLNEHIVCCLCAGYFVDATTITECLHTFCKSCIVKYLQTSKYCPMC 85
           R++ +   +   C +C G   +A T+ +C H+FC+ CI + LQ  K CPMC
Sbjct: 152 RLREEAEEQESTCPICLGEIQNAKTLEKCRHSFCEGCITRALQVKKACPMC 202


>gi|87080813 LON peptidase N-terminal domain and ring finger 1 [Homo
           sapiens]
          Length = 773

 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 24/77 (31%), Positives = 43/77 (55%), Gaps = 2/77 (2%)

Query: 47  CCLCAGYFVDATTITECLHTFCKSCIVKYLQTSKYCPMCNIKIHETQPLLNLKLDRVMQD 106
           C LC   F +  T T C H+FCK+C+ + L  + YCP+C   + E        + +++++
Sbjct: 479 CSLCMRLFFEPVT-TPCGHSFCKNCLERCLDHAPYCPLCKESLKEYLADRRYCVTQLLEE 537

Query: 107 IVYKLVPGLQDSEEKRI 123
           ++ K +P  + SE K+I
Sbjct: 538 LIVKYLPD-ELSERKKI 553


>gi|148528975 LON peptidase N-terminal domain and ring finger 2
           [Homo sapiens]
          Length = 754

 Score = 49.3 bits (116), Expect = 3e-06
 Identities = 23/77 (29%), Positives = 41/77 (53%), Gaps = 2/77 (2%)

Query: 47  CCLCAGYFVDATTITECLHTFCKSCIVKYLQTSKYCPMCNIKIHETQPLLNLKLDRVMQD 106
           C LC     +  T T C HTFC  C+ + L  + +CP+C  K+ E     N  +  + ++
Sbjct: 449 CALCMRLLFEPVT-TPCGHTFCLKCLERCLDHAPHCPLCKDKLSELLASRNFNITVLAEE 507

Query: 107 IVYKLVPGLQDSEEKRI 123
           ++++ +P  + S+ KRI
Sbjct: 508 LIFRYLPD-ELSDRKRI 523


>gi|239048909 checkpoint with forkhead and ring finger domains
           isoform 5 [Homo sapiens]
          Length = 572

 Score = 48.1 bits (113), Expect = 7e-06
 Identities = 34/135 (25%), Positives = 63/135 (46%), Gaps = 21/135 (15%)

Query: 7   GQIAIAMRLRNQLQSVYKMDPLRNEEEVRV---KIKDLNEHIVCCLCAGYFVDATTITEC 63
           GQ+ +A   RN  Q+V+        E+VR    K   + E + C +C     D  ++  C
Sbjct: 178 GQLLVAQPRRNA-QTVH--------EDVRAAAGKPDKMEETLTCIICQDLLHDCVSLQPC 228

Query: 64  LHTFCKSCIVKYLQTSKYCPMCNIKIHETQPLLNLKLDRVMQDIVYKLVPGLQDSEEKRI 123
           +HTFC +C   +++ S  CP C        P+  +  + ++ ++V   +  +Q  ++ R 
Sbjct: 229 MHTFCAACYSGWMERSSLCPTCRC------PVERICKNHILNNLVEAYL--IQHPDKSRS 280

Query: 124 REFYQSR-GLDRVTQ 137
            E  QS    +++TQ
Sbjct: 281 EEDVQSMDARNKITQ 295


>gi|239048905 checkpoint with forkhead and ring finger domains
           isoform 3 [Homo sapiens]
          Length = 652

 Score = 48.1 bits (113), Expect = 7e-06
 Identities = 34/135 (25%), Positives = 63/135 (46%), Gaps = 21/135 (15%)

Query: 7   GQIAIAMRLRNQLQSVYKMDPLRNEEEVRV---KIKDLNEHIVCCLCAGYFVDATTITEC 63
           GQ+ +A   RN  Q+V+        E+VR    K   + E + C +C     D  ++  C
Sbjct: 258 GQLLVAQPRRNA-QTVH--------EDVRAAAGKPDKMEETLTCIICQDLLHDCVSLQPC 308

Query: 64  LHTFCKSCIVKYLQTSKYCPMCNIKIHETQPLLNLKLDRVMQDIVYKLVPGLQDSEEKRI 123
           +HTFC +C   +++ S  CP C        P+  +  + ++ ++V   +  +Q  ++ R 
Sbjct: 309 MHTFCAACYSGWMERSSLCPTCRC------PVERICKNHILNNLVEAYL--IQHPDKSRS 360

Query: 124 REFYQSR-GLDRVTQ 137
            E  QS    +++TQ
Sbjct: 361 EEDVQSMDARNKITQ 375


>gi|239048862 checkpoint with forkhead and ring finger domains
           isoform 2 [Homo sapiens]
          Length = 663

 Score = 48.1 bits (113), Expect = 7e-06
 Identities = 34/135 (25%), Positives = 63/135 (46%), Gaps = 21/135 (15%)

Query: 7   GQIAIAMRLRNQLQSVYKMDPLRNEEEVRV---KIKDLNEHIVCCLCAGYFVDATTITEC 63
           GQ+ +A   RN  Q+V+        E+VR    K   + E + C +C     D  ++  C
Sbjct: 270 GQLLVAQPRRNA-QTVH--------EDVRAAAGKPDKMEETLTCIICQDLLHDCVSLQPC 320

Query: 64  LHTFCKSCIVKYLQTSKYCPMCNIKIHETQPLLNLKLDRVMQDIVYKLVPGLQDSEEKRI 123
           +HTFC +C   +++ S  CP C        P+  +  + ++ ++V   +  +Q  ++ R 
Sbjct: 321 MHTFCAACYSGWMERSSLCPTCRC------PVERICKNHILNNLVEAYL--IQHPDKSRS 372

Query: 124 REFYQSR-GLDRVTQ 137
            E  QS    +++TQ
Sbjct: 373 EEDVQSMDARNKITQ 387


>gi|239048792 checkpoint with forkhead and ring finger domains
           isoform 1 [Homo sapiens]
          Length = 664

 Score = 48.1 bits (113), Expect = 7e-06
 Identities = 34/135 (25%), Positives = 63/135 (46%), Gaps = 21/135 (15%)

Query: 7   GQIAIAMRLRNQLQSVYKMDPLRNEEEVRV---KIKDLNEHIVCCLCAGYFVDATTITEC 63
           GQ+ +A   RN  Q+V+        E+VR    K   + E + C +C     D  ++  C
Sbjct: 270 GQLLVAQPRRNA-QTVH--------EDVRAAAGKPDKMEETLTCIICQDLLHDCVSLQPC 320

Query: 64  LHTFCKSCIVKYLQTSKYCPMCNIKIHETQPLLNLKLDRVMQDIVYKLVPGLQDSEEKRI 123
           +HTFC +C   +++ S  CP C        P+  +  + ++ ++V   +  +Q  ++ R 
Sbjct: 321 MHTFCAACYSGWMERSSLCPTCRC------PVERICKNHILNNLVEAYL--IQHPDKSRS 372

Query: 124 REFYQSR-GLDRVTQ 137
            E  QS    +++TQ
Sbjct: 373 EEDVQSMDARNKITQ 387


>gi|239048907 checkpoint with forkhead and ring finger domains
           isoform 4 [Homo sapiens]
          Length = 623

 Score = 48.1 bits (113), Expect = 7e-06
 Identities = 34/135 (25%), Positives = 63/135 (46%), Gaps = 21/135 (15%)

Query: 7   GQIAIAMRLRNQLQSVYKMDPLRNEEEVRV---KIKDLNEHIVCCLCAGYFVDATTITEC 63
           GQ+ +A   RN  Q+V+        E+VR    K   + E + C +C     D  ++  C
Sbjct: 229 GQLLVAQPRRNA-QTVH--------EDVRAAAGKPDKMEETLTCIICQDLLHDCVSLQPC 279

Query: 64  LHTFCKSCIVKYLQTSKYCPMCNIKIHETQPLLNLKLDRVMQDIVYKLVPGLQDSEEKRI 123
           +HTFC +C   +++ S  CP C        P+  +  + ++ ++V   +  +Q  ++ R 
Sbjct: 280 MHTFCAACYSGWMERSSLCPTCRC------PVERICKNHILNNLVEAYL--IQHPDKSRS 331

Query: 124 REFYQSR-GLDRVTQ 137
            E  QS    +++TQ
Sbjct: 332 EEDVQSMDARNKITQ 346


>gi|239755486 PREDICTED: tripartite motif-containing protein
          64C-like isoform 2 [Homo sapiens]
          Length = 447

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 19/57 (33%), Positives = 33/57 (57%), Gaps = 5/57 (8%)

Query: 38 IKDLNEHIVCCLCAGYFVDATTITECLHTFCKSCIVKYLQTSK---YCPMCNIKIHE 91
          ++     ++CC+C  YF+D  T T+C+H+FC+ C+    +  +    CP+C  KI E
Sbjct: 6  LRVFQNELICCICVNYFIDPVT-TDCVHSFCRPCLCLCSEEGRAPMRCPLCR-KISE 60


>gi|239755484 PREDICTED: tripartite motif-containing protein
          64C-like isoform 1 [Homo sapiens]
          Length = 450

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 19/57 (33%), Positives = 33/57 (57%), Gaps = 5/57 (8%)

Query: 38 IKDLNEHIVCCLCAGYFVDATTITECLHTFCKSCIVKYLQTSK---YCPMCNIKIHE 91
          ++     ++CC+C  YF+D  T T+C+H+FC+ C+    +  +    CP+C  KI E
Sbjct: 6  LRVFQNELICCICVNYFIDPVT-TDCVHSFCRPCLCLCSEEGRAPMRCPLCR-KISE 60


>gi|239750044 PREDICTED: tripartite motif-containing protein
          64C-like isoform 2 [Homo sapiens]
          Length = 447

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 19/57 (33%), Positives = 33/57 (57%), Gaps = 5/57 (8%)

Query: 38 IKDLNEHIVCCLCAGYFVDATTITECLHTFCKSCIVKYLQTSK---YCPMCNIKIHE 91
          ++     ++CC+C  YF+D  T T+C+H+FC+ C+    +  +    CP+C  KI E
Sbjct: 6  LRVFQNELICCICVNYFIDPVT-TDCVHSFCRPCLCLCSEEGRAPMRCPLCR-KISE 60


>gi|239750042 PREDICTED: tripartite motif-containing protein
          64C-like isoform 1 [Homo sapiens]
          Length = 450

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 19/57 (33%), Positives = 33/57 (57%), Gaps = 5/57 (8%)

Query: 38 IKDLNEHIVCCLCAGYFVDATTITECLHTFCKSCIVKYLQTSK---YCPMCNIKIHE 91
          ++     ++CC+C  YF+D  T T+C+H+FC+ C+    +  +    CP+C  KI E
Sbjct: 6  LRVFQNELICCICVNYFIDPVT-TDCVHSFCRPCLCLCSEEGRAPMRCPLCR-KISE 60


>gi|239744355 PREDICTED: tripartite motif-containing protein
          64C-like isoform 1 [Homo sapiens]
          Length = 447

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 19/57 (33%), Positives = 33/57 (57%), Gaps = 5/57 (8%)

Query: 38 IKDLNEHIVCCLCAGYFVDATTITECLHTFCKSCIVKYLQTSK---YCPMCNIKIHE 91
          ++     ++CC+C  YF+D  T T+C+H+FC+ C+    +  +    CP+C  KI E
Sbjct: 6  LRVFQNELICCICVNYFIDPVT-TDCVHSFCRPCLCLCSEEGRAPMRCPLCR-KISE 60


>gi|239744353 PREDICTED: tripartite motif-containing protein
          64C-like isoform 2 [Homo sapiens]
          Length = 450

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 19/57 (33%), Positives = 33/57 (57%), Gaps = 5/57 (8%)

Query: 38 IKDLNEHIVCCLCAGYFVDATTITECLHTFCKSCIVKYLQTSK---YCPMCNIKIHE 91
          ++     ++CC+C  YF+D  T T+C+H+FC+ C+    +  +    CP+C  KI E
Sbjct: 6  LRVFQNELICCICVNYFIDPVT-TDCVHSFCRPCLCLCSEEGRAPMRCPLCR-KISE 60


>gi|34878777 ring finger protein 20 [Homo sapiens]
          Length = 975

 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 25/75 (33%), Positives = 39/75 (52%), Gaps = 3/75 (4%)

Query: 14  RLRNQLQSVYKMDPLRNEEEVRVK-IKDLNEHIVCCLCAGYFVDATTITECLHTFCKSCI 72
           RLR +L++  K D +   +E+ ++ IKD    + C  C     DA  +T+C H FC  C+
Sbjct: 888 RLRRKLETTKKPDNVPKCDEILMEEIKDYKARLTCPCCNMRKKDAV-LTKCFHVFCFECV 946

Query: 73  -VKYLQTSKYCPMCN 86
             +Y    + CP CN
Sbjct: 947 KTRYDTRQRKCPKCN 961


>gi|73747840 LON peptidase N-terminal domain and ring finger 3
           isoform 1 [Homo sapiens]
          Length = 759

 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 23/82 (28%), Positives = 39/82 (47%), Gaps = 5/82 (6%)

Query: 47  CCLCAGYFVDATTITECLHTFCKSCIVKYLQTSKYCPMCNIKIHETQPLLNLKLDRVMQD 106
           C LC   F +  T T C HTFC  C+ + L  +  CP+C   + +         + +M++
Sbjct: 467 CALCMRLFYEPVT-TPCGHTFCLKCLERCLDHNAKCPLCKDGLSQCLASRKYSKNVIMEE 525

Query: 107 IVYKLVPGLQDSEEKRIREFYQ 128
           ++ K +P     E K  R+ Y+
Sbjct: 526 LIAKFLP----EELKERRKLYE 543



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 22/83 (26%), Positives = 38/83 (45%), Gaps = 16/83 (19%)

Query: 47  CCLCAGYFVDATTITECLHTFCKSCIVKYLQTSKYCPMCNIKIHE--------------- 91
           C  C G+  D  +++ C HTFCK C+ +     + C +C +K+                 
Sbjct: 158 CRKCHGFLSDPVSLS-CGHTFCKLCLERGRAADRRCALCGVKLSALMVATGRARGARRAG 216

Query: 92  TQPLLNLKLDRVMQDIVYKLVPG 114
            QP   L+++ V+  ++ KL PG
Sbjct: 217 QQPPPPLRVNVVLSGLLGKLFPG 239


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.137    0.419 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,276,336
Number of Sequences: 37866
Number of extensions: 449433
Number of successful extensions: 1517
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 125
Number of HSP's successfully gapped in prelim test: 169
Number of HSP's that attempted gapping in prelim test: 1312
Number of HSP's gapped (non-prelim): 310
length of query: 259
length of database: 18,247,518
effective HSP length: 100
effective length of query: 159
effective length of database: 14,460,918
effective search space: 2299285962
effective search space used: 2299285962
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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