Search of human proteins with 4557843

Search of human proteins with 4557843

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4557843 regulatory factor X, 5 [Homo sapiens]
         (616 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|71040090 regulatory factor X, 5 [Homo sapiens]                    1238   0.0  
gi|4557843 regulatory factor X, 5 [Homo sapiens]                     1238   0.0  
gi|148613886 regulatory factor X domain containing 2 [Homo sapiens]   227   2e-59
gi|15011898 regulatory factor X4 isoform b [Homo sapiens]              67   4e-11
gi|47132527 regulatory factor X4 isoform c [Homo sapiens]              66   8e-11
gi|19743879 regulatory factor X2 isoform b [Homo sapiens]              64   3e-10
gi|19743881 regulatory factor X2 isoform a [Homo sapiens]              64   4e-10
gi|4506495 regulatory factor X3 isoform a [Homo sapiens]               63   9e-10
gi|19743884 regulatory factor X3 isoform b [Homo sapiens]              63   9e-10
gi|238859557 regulatory factor X1 [Homo sapiens]                       60   8e-09
gi|27734871 regulatory factor X, 6 [Homo sapiens]                      52   1e-06
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    52   2e-06
gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Hom...    50   6e-06
gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Hom...    50   6e-06
gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo ...    50   6e-06
gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens]                  49   1e-05
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    49   1e-05
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    49   1e-05
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    49   1e-05
gi|18079216 CASK interacting protein 1 [Homo sapiens]                  48   3e-05
gi|56549668 AT rich interactive domain 2 (ARID, RFX-like) [Homo ...    48   3e-05
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    47   4e-05
gi|116734704 interferon regulatory factor 2 binding protein 2 is...    47   4e-05
gi|157785645 SPEG complex locus [Homo sapiens]                         47   5e-05
gi|7669528 neuregulin 2 isoform 2 [Homo sapiens]                       46   9e-05
gi|7669532 neuregulin 2 isoform 4 [Homo sapiens]                       46   9e-05
gi|7669530 neuregulin 2 isoform 3 [Homo sapiens]                       46   9e-05
gi|4758832 neuregulin 2 isoform 1 [Homo sapiens]                       46   9e-05
gi|239752764 PREDICTED: hypothetical protein [Homo sapiens]            46   1e-04
gi|146134388 YLP motif containing 1 [Homo sapiens]                     46   1e-04

>gi|71040090 regulatory factor X, 5 [Homo sapiens]
          Length = 616

 Score = 1238 bits (3203), Expect = 0.0
 Identities = 616/616 (100%), Positives = 616/616 (100%)

Query: 1   MAEDEPDAKSPKTGGRAPPGGAEAGEPTTLLQRLRGTISKAVQNKVEGILQDVQKFSDND 60
           MAEDEPDAKSPKTGGRAPPGGAEAGEPTTLLQRLRGTISKAVQNKVEGILQDVQKFSDND
Sbjct: 1   MAEDEPDAKSPKTGGRAPPGGAEAGEPTTLLQRLRGTISKAVQNKVEGILQDVQKFSDND 60

Query: 61  KLYLYLQLPSGPTTGDKSSEPSTLSNEEYMYAYRWIRNHLEEHTDTCLPKQSVYDAYRKY 120
           KLYLYLQLPSGPTTGDKSSEPSTLSNEEYMYAYRWIRNHLEEHTDTCLPKQSVYDAYRKY
Sbjct: 61  KLYLYLQLPSGPTTGDKSSEPSTLSNEEYMYAYRWIRNHLEEHTDTCLPKQSVYDAYRKY 120

Query: 121 CESLACCRPLSTANFGKIIREIFPDIKARRLGGRGQSKYCYSGIRRKTLVSMPPLPGLDL 180
           CESLACCRPLSTANFGKIIREIFPDIKARRLGGRGQSKYCYSGIRRKTLVSMPPLPGLDL
Sbjct: 121 CESLACCRPLSTANFGKIIREIFPDIKARRLGGRGQSKYCYSGIRRKTLVSMPPLPGLDL 180

Query: 181 KGSESPEMGPEVTPAPRDELVEAACALTCDWAERILKRSFSSIVEVARFLLQQHLISARS 240
           KGSESPEMGPEVTPAPRDELVEAACALTCDWAERILKRSFSSIVEVARFLLQQHLISARS
Sbjct: 181 KGSESPEMGPEVTPAPRDELVEAACALTCDWAERILKRSFSSIVEVARFLLQQHLISARS 240

Query: 241 AHAHVLKAMGLAEEDEHAPRERSSKPKNGLENPEGGAHKKPERLAQPPKDLEARTGAGPL 300
           AHAHVLKAMGLAEEDEHAPRERSSKPKNGLENPEGGAHKKPERLAQPPKDLEARTGAGPL
Sbjct: 241 AHAHVLKAMGLAEEDEHAPRERSSKPKNGLENPEGGAHKKPERLAQPPKDLEARTGAGPL 300

Query: 301 ARGERKKSVVESSAPGANNLQVNALVARLPLLLPRAPRSLIPPIPVSPPILAPRLSSGAL 360
           ARGERKKSVVESSAPGANNLQVNALVARLPLLLPRAPRSLIPPIPVSPPILAPRLSSGAL
Sbjct: 301 ARGERKKSVVESSAPGANNLQVNALVARLPLLLPRAPRSLIPPIPVSPPILAPRLSSGAL 360

Query: 361 KVATLPLSSRAGAPPAAVPIINMILPTVPALPGPGPGPGRAPPGGLTQPRGTENREVGIG 420
           KVATLPLSSRAGAPPAAVPIINMILPTVPALPGPGPGPGRAPPGGLTQPRGTENREVGIG
Sbjct: 361 KVATLPLSSRAGAPPAAVPIINMILPTVPALPGPGPGPGRAPPGGLTQPRGTENREVGIG 420

Query: 421 GDQGPHDKGVKRTAEVPVSEASGQAPPAKAAKQDIEDTASDAKRKRGRPRKKSGGSGERN 480
           GDQGPHDKGVKRTAEVPVSEASGQAPPAKAAKQDIEDTASDAKRKRGRPRKKSGGSGERN
Sbjct: 421 GDQGPHDKGVKRTAEVPVSEASGQAPPAKAAKQDIEDTASDAKRKRGRPRKKSGGSGERN 480

Query: 481 STPLKSAAAMESAQSSRLPWETWGSGGEGNSAGGAERPGPMGEAEKGAVLAQGQGDGTVS 540
           STPLKSAAAMESAQSSRLPWETWGSGGEGNSAGGAERPGPMGEAEKGAVLAQGQGDGTVS
Sbjct: 481 STPLKSAAAMESAQSSRLPWETWGSGGEGNSAGGAERPGPMGEAEKGAVLAQGQGDGTVS 540

Query: 541 KGGRGPGSQHTKEAEDKIPLVPSKVSVIKGSRSQKEAFPLAKGEVDTAPQGNKDLKEHVL 600
           KGGRGPGSQHTKEAEDKIPLVPSKVSVIKGSRSQKEAFPLAKGEVDTAPQGNKDLKEHVL
Sbjct: 541 KGGRGPGSQHTKEAEDKIPLVPSKVSVIKGSRSQKEAFPLAKGEVDTAPQGNKDLKEHVL 600

Query: 601 QSSLSQEHKDPKATPP 616
           QSSLSQEHKDPKATPP
Sbjct: 601 QSSLSQEHKDPKATPP 616


>gi|4557843 regulatory factor X, 5 [Homo sapiens]
          Length = 616

 Score = 1238 bits (3203), Expect = 0.0
 Identities = 616/616 (100%), Positives = 616/616 (100%)

Query: 1   MAEDEPDAKSPKTGGRAPPGGAEAGEPTTLLQRLRGTISKAVQNKVEGILQDVQKFSDND 60
           MAEDEPDAKSPKTGGRAPPGGAEAGEPTTLLQRLRGTISKAVQNKVEGILQDVQKFSDND
Sbjct: 1   MAEDEPDAKSPKTGGRAPPGGAEAGEPTTLLQRLRGTISKAVQNKVEGILQDVQKFSDND 60

Query: 61  KLYLYLQLPSGPTTGDKSSEPSTLSNEEYMYAYRWIRNHLEEHTDTCLPKQSVYDAYRKY 120
           KLYLYLQLPSGPTTGDKSSEPSTLSNEEYMYAYRWIRNHLEEHTDTCLPKQSVYDAYRKY
Sbjct: 61  KLYLYLQLPSGPTTGDKSSEPSTLSNEEYMYAYRWIRNHLEEHTDTCLPKQSVYDAYRKY 120

Query: 121 CESLACCRPLSTANFGKIIREIFPDIKARRLGGRGQSKYCYSGIRRKTLVSMPPLPGLDL 180
           CESLACCRPLSTANFGKIIREIFPDIKARRLGGRGQSKYCYSGIRRKTLVSMPPLPGLDL
Sbjct: 121 CESLACCRPLSTANFGKIIREIFPDIKARRLGGRGQSKYCYSGIRRKTLVSMPPLPGLDL 180

Query: 181 KGSESPEMGPEVTPAPRDELVEAACALTCDWAERILKRSFSSIVEVARFLLQQHLISARS 240
           KGSESPEMGPEVTPAPRDELVEAACALTCDWAERILKRSFSSIVEVARFLLQQHLISARS
Sbjct: 181 KGSESPEMGPEVTPAPRDELVEAACALTCDWAERILKRSFSSIVEVARFLLQQHLISARS 240

Query: 241 AHAHVLKAMGLAEEDEHAPRERSSKPKNGLENPEGGAHKKPERLAQPPKDLEARTGAGPL 300
           AHAHVLKAMGLAEEDEHAPRERSSKPKNGLENPEGGAHKKPERLAQPPKDLEARTGAGPL
Sbjct: 241 AHAHVLKAMGLAEEDEHAPRERSSKPKNGLENPEGGAHKKPERLAQPPKDLEARTGAGPL 300

Query: 301 ARGERKKSVVESSAPGANNLQVNALVARLPLLLPRAPRSLIPPIPVSPPILAPRLSSGAL 360
           ARGERKKSVVESSAPGANNLQVNALVARLPLLLPRAPRSLIPPIPVSPPILAPRLSSGAL
Sbjct: 301 ARGERKKSVVESSAPGANNLQVNALVARLPLLLPRAPRSLIPPIPVSPPILAPRLSSGAL 360

Query: 361 KVATLPLSSRAGAPPAAVPIINMILPTVPALPGPGPGPGRAPPGGLTQPRGTENREVGIG 420
           KVATLPLSSRAGAPPAAVPIINMILPTVPALPGPGPGPGRAPPGGLTQPRGTENREVGIG
Sbjct: 361 KVATLPLSSRAGAPPAAVPIINMILPTVPALPGPGPGPGRAPPGGLTQPRGTENREVGIG 420

Query: 421 GDQGPHDKGVKRTAEVPVSEASGQAPPAKAAKQDIEDTASDAKRKRGRPRKKSGGSGERN 480
           GDQGPHDKGVKRTAEVPVSEASGQAPPAKAAKQDIEDTASDAKRKRGRPRKKSGGSGERN
Sbjct: 421 GDQGPHDKGVKRTAEVPVSEASGQAPPAKAAKQDIEDTASDAKRKRGRPRKKSGGSGERN 480

Query: 481 STPLKSAAAMESAQSSRLPWETWGSGGEGNSAGGAERPGPMGEAEKGAVLAQGQGDGTVS 540
           STPLKSAAAMESAQSSRLPWETWGSGGEGNSAGGAERPGPMGEAEKGAVLAQGQGDGTVS
Sbjct: 481 STPLKSAAAMESAQSSRLPWETWGSGGEGNSAGGAERPGPMGEAEKGAVLAQGQGDGTVS 540

Query: 541 KGGRGPGSQHTKEAEDKIPLVPSKVSVIKGSRSQKEAFPLAKGEVDTAPQGNKDLKEHVL 600
           KGGRGPGSQHTKEAEDKIPLVPSKVSVIKGSRSQKEAFPLAKGEVDTAPQGNKDLKEHVL
Sbjct: 541 KGGRGPGSQHTKEAEDKIPLVPSKVSVIKGSRSQKEAFPLAKGEVDTAPQGNKDLKEHVL 600

Query: 601 QSSLSQEHKDPKATPP 616
           QSSLSQEHKDPKATPP
Sbjct: 601 QSSLSQEHKDPKATPP 616


>gi|148613886 regulatory factor X domain containing 2 [Homo sapiens]
          Length = 1460

 Score =  227 bits (579), Expect = 2e-59
 Identities = 147/437 (33%), Positives = 227/437 (51%), Gaps = 48/437 (10%)

Query: 1   MAEDE--PDAKSPKTGGRAPPGGAEAG-------------EPTTLLQRLRGTISKAVQNK 45
           MAE++  P  + P    + PP    +G             E + L  +++ +I K VQ+K
Sbjct: 1   MAEEQQQPPPQQPDAHQQLPPSAPNSGVALPALVPGLPGTEASALQHKIKNSICKTVQSK 60

Query: 46  VEGILQDVQKFSDNDKLYLYLQLPSGPTTGDKSSEPSTLSNE-EYMYAYRWIRNHLEEHT 104
           V+ ILQ+V+KF+D +KLYLYLQLPSG + G+KS + +  S+  + M+A+ WIRN LEEH 
Sbjct: 61  VDCILQEVEKFTDLEKLYLYLQLPSGLSNGEKSDQNAMSSSRAQQMHAFSWIRNTLEEHP 120

Query: 105 DTCLPKQSVYDAYRKYCESLACCRPLSTANFGKIIREIFPDIKARRLGGRGQSKYCYSGI 164
           +T LPKQ VYD Y+ YC++L    PLS A+FGKI++ +FP++KARRLG RG+SKYCYSG+
Sbjct: 121 ETSLPKQEVYDEYKSYCDNLGY-HPLSAADFGKIMKNVFPNMKARRLGTRGKSKYCYSGL 179

Query: 165 RRKTLVSMPPLPGLDL----KGSESPEMGPEVTPAPRDELVEAACALTCDWAERILKRSF 220
           R+K  V MP LP LD      G E  E   ++     +E++ +AC L C+WA+++L + F
Sbjct: 180 RKKAFVHMPTLPNLDFHKTGDGLEGAEPSGQLQNID-EEVISSACRLVCEWAQKVLSQPF 238

Query: 221 SSIVEVARFLLQQHLISARSAHAHVLKA------MGLAEEDEHAPRERSSKPKNGLENPE 274
            +++E+ARFL++ H I  +S  A  + A       G+ +     P   S+  +  ++   
Sbjct: 239 DTVLELARFLVKSHYIGTKSMAALTVMAAAPAGMKGITQPSAFIPTAESNSFQPQVKTLP 298

Query: 275 GGAHKKPERLAQPPKDLEARTGAGPLARGERKKSVVESSAPGANNLQVNALVARLPLLLP 334
                K +   +  K  + +    PL      K    +++ G  N             LP
Sbjct: 299 SPIDAKQQLQRKIQKKQQEQKLQSPLPGESAAKKSESATSNGVTN-------------LP 345

Query: 335 RAPRSLIPPIPVSPPILA-----PRLSSGALKVATLPLSSRAG-APPAAVPIINMILPTV 388
               S++ P P+   + A     P   +  L  +  P+SS  G   P  V ++   + +V
Sbjct: 346 NGNPSILSPQPIGIVVAAVPSPIPVQRTRQLVTSPSPMSSSDGKVLPLNVQVVTQHMQSV 405

Query: 389 PALPGPGPGPGRAPPGG 405
              P   P    A PGG
Sbjct: 406 KQAP-KTPQNVPASPGG 421


>gi|15011898 regulatory factor X4 isoform b [Homo sapiens]
          Length = 563

 Score = 67.4 bits (163), Expect = 4e-11
 Identities = 50/153 (32%), Positives = 76/153 (49%), Gaps = 14/153 (9%)

Query: 16  RAPPGGAEAGEPTTLLQRLRGTISKAVQNKVEGILQDVQKFSDNDKLYLYLQLPSGPTTG 75
           RA PG   AG   T  +R R T     ++ +E  L +    S+N +   +  L +     
Sbjct: 5   RAHPG---AGGDRTRPRRRRST-----ESWIERCLNE----SENKRYSSHTSLGNVSNDE 52

Query: 76  DKSSEPSTLSNEEYMYA-YRWIRNHLEEHTDTCLPKQSVYDAYRKYCESLACCRPLSTAN 134
           ++  E +  S      A  +W+  + E     C+P+ ++Y  Y  +CE     +P++ A+
Sbjct: 53  NEEKENNRASKPHSTPATLQWLEENYEIAEGVCIPRSALYMHYLDFCEKNDT-QPVNAAS 111

Query: 135 FGKIIREIFPDIKARRLGGRGQSKYCYSGIRRK 167
           FGKIIR+ FP +  RRLG RGQSKY Y GI  K
Sbjct: 112 FGKIIRQQFPQLTTRRLGTRGQSKYHYYGIAVK 144


>gi|47132527 regulatory factor X4 isoform c [Homo sapiens]
          Length = 735

 Score = 66.2 bits (160), Expect = 8e-11
 Identities = 32/74 (43%), Positives = 46/74 (62%), Gaps = 1/74 (1%)

Query: 94  RWIRNHLEEHTDTCLPKQSVYDAYRKYCESLACCRPLSTANFGKIIREIFPDIKARRLGG 153
           +W+  + E     C+P+ ++Y  Y  +CE     +P++ A+FGKIIR+ FP +  RRLG 
Sbjct: 63  QWLEENYEIAEGVCIPRSALYMHYLDFCEKNDT-QPVNAASFGKIIRQQFPQLTTRRLGT 121

Query: 154 RGQSKYCYSGIRRK 167
           RGQSKY Y GI  K
Sbjct: 122 RGQSKYHYYGIAVK 135


>gi|19743879 regulatory factor X2 isoform b [Homo sapiens]
          Length = 698

 Score = 64.3 bits (155), Expect = 3e-10
 Identities = 34/89 (38%), Positives = 52/89 (58%), Gaps = 10/89 (11%)

Query: 79  SEPSTLSNEEYMYAYRWIRNHLEEHTDTCLPKQSVYDAYRKYCESLACCRPLSTANFGKI 138
           S P+TL         +W+ ++ E      LP+ S+Y+ Y ++C+      P++ A+FGK+
Sbjct: 170 SSPATL---------QWLLDNYETAEGVSLPRSSLYNHYLRHCQEHKL-DPVNAASFGKL 219

Query: 139 IREIFPDIKARRLGGRGQSKYCYSGIRRK 167
           IR +F  ++ RRLG RG SKY Y GIR K
Sbjct: 220 IRSVFMGLRTRRLGTRGNSKYHYYGIRLK 248


>gi|19743881 regulatory factor X2 isoform a [Homo sapiens]
          Length = 723

 Score = 63.9 bits (154), Expect = 4e-10
 Identities = 30/74 (40%), Positives = 47/74 (63%), Gaps = 1/74 (1%)

Query: 94  RWIRNHLEEHTDTCLPKQSVYDAYRKYCESLACCRPLSTANFGKIIREIFPDIKARRLGG 153
           +W+ ++ E      LP+ S+Y+ Y ++C+      P++ A+FGK+IR +F  ++ RRLG 
Sbjct: 201 QWLLDNYETAEGVSLPRSSLYNHYLRHCQEHKL-DPVNAASFGKLIRSVFMGLRTRRLGT 259

Query: 154 RGQSKYCYSGIRRK 167
           RG SKY Y GIR K
Sbjct: 260 RGNSKYHYYGIRLK 273


>gi|4506495 regulatory factor X3 isoform a [Homo sapiens]
          Length = 707

 Score = 62.8 bits (151), Expect = 9e-10
 Identities = 30/74 (40%), Positives = 47/74 (63%), Gaps = 1/74 (1%)

Query: 94  RWIRNHLEEHTDTCLPKQSVYDAYRKYCESLACCRPLSTANFGKIIREIFPDIKARRLGG 153
           +W+ ++ E      LP+ ++Y+ Y ++C+      P++ A+FGK+IR IF  ++ RRLG 
Sbjct: 185 QWLLDNYETAEGVSLPRSTLYNHYLRHCQEHKL-DPVNAASFGKLIRSIFMGLRTRRLGT 243

Query: 154 RGQSKYCYSGIRRK 167
           RG SKY Y GIR K
Sbjct: 244 RGNSKYHYYGIRVK 257


>gi|19743884 regulatory factor X3 isoform b [Homo sapiens]
          Length = 749

 Score = 62.8 bits (151), Expect = 9e-10
 Identities = 30/74 (40%), Positives = 47/74 (63%), Gaps = 1/74 (1%)

Query: 94  RWIRNHLEEHTDTCLPKQSVYDAYRKYCESLACCRPLSTANFGKIIREIFPDIKARRLGG 153
           +W+ ++ E      LP+ ++Y+ Y ++C+      P++ A+FGK+IR IF  ++ RRLG 
Sbjct: 185 QWLLDNYETAEGVSLPRSTLYNHYLRHCQEHKL-DPVNAASFGKLIRSIFMGLRTRRLGT 243

Query: 154 RGQSKYCYSGIRRK 167
           RG SKY Y GIR K
Sbjct: 244 RGNSKYHYYGIRVK 257


>gi|238859557 regulatory factor X1 [Homo sapiens]
          Length = 979

 Score = 59.7 bits (143), Expect = 8e-09
 Identities = 28/74 (37%), Positives = 45/74 (60%), Gaps = 1/74 (1%)

Query: 94  RWIRNHLEEHTDTCLPKQSVYDAYRKYCESLACCRPLSTANFGKIIREIFPDIKARRLGG 153
           +W+ ++ E      LP+ ++Y  Y  +C+      P++ A+FGK+IR +F  ++ RRLG 
Sbjct: 440 QWLLDNYETAEGVSLPRSTLYCHYLLHCQEQKL-EPVNAASFGKLIRSVFMGLRTRRLGT 498

Query: 154 RGQSKYCYSGIRRK 167
           RG SKY Y G+R K
Sbjct: 499 RGNSKYHYYGLRIK 512



 Score = 34.7 bits (78), Expect = 0.27
 Identities = 60/257 (23%), Positives = 91/257 (35%), Gaps = 34/257 (13%)

Query: 306 KKSVVESSAPGANNLQVNALVARLPLLLPRAPRSLIPPIPVSPPILAPRLSS--GALKVA 363
           ++ VV+S+APG+   QV+  V           + +  P P   P+ A   SS        
Sbjct: 176 QRLVVQSAAPGSKGGQVSLTV--------HGTQQVHSP-PEQSPVQANSSSSKTAGAPTG 226

Query: 364 TLPLSSRAGAPPAAVPIIN--MILPTVPALPGPGPGPGRAPPGGLTQPRGTENREVGIGG 421
           T+P   +      +VP+     ++   P  P PGP       G   QP         +  
Sbjct: 227 TVPQQLQVHGVQQSVPVTQERSVVQATPQAPKPGPVQPLTVQG--LQPVHVAQEVQQLQQ 284

Query: 422 DQGPHDKGVKRTAEVPVSEASGQAPPAKAAKQDIEDTASDAKRKRGRPRKKSGGSGERNS 481
              PH     +   V   +AS  A   +++     +T    +        ++ G+  + S
Sbjct: 285 VPVPHVYS-SQVQYVEGGDASYTASAIRSSTYSYPETPLYTQTA-STSYYEAAGTATQVS 342

Query: 482 TPLKSAAAMESAQSSRLPWETWGS----------GGEGNSAGGAERPGPMGEAEKGAVLA 531
           TP  S A    A S  +P    GS           G  NS+GG    G  G    G    
Sbjct: 343 TPATSQAV---ASSGSMPMYVSGSQVVASSTSTGAGASNSSGGGGSGGGGGGGGGGG--- 396

Query: 532 QGQGDGTVSKGGRGPGS 548
            G G G+   GG G G+
Sbjct: 397 -GGGSGSTGGGGSGAGT 412


>gi|27734871 regulatory factor X, 6 [Homo sapiens]
          Length = 928

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 28/71 (39%), Positives = 36/71 (50%), Gaps = 1/71 (1%)

Query: 94  RWIRNHLEEHTDTCLPKQSVYDAYRKYCESLACCRPLSTANFGKIIREIFPDIKARRLGG 153
           +W+  +       CLP+  +Y  Y  +C       P   A FGK IR+ FP +  RRLG 
Sbjct: 126 QWLEENYIVCEGVCLPRCILYAHYLDFCRKEKL-EPACAATFGKTIRQKFPLLTTRRLGT 184

Query: 154 RGQSKYCYSGI 164
           RG SKY Y GI
Sbjct: 185 RGHSKYHYYGI 195


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 1124

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 88/374 (23%), Positives = 128/374 (34%), Gaps = 54/374 (14%)

Query: 252  AEEDEHAPRERSSKPKNGLENPEGGAHKKPERLAQPPKDLEARTGAGPLARGERKKSVVE 311
            A     AP   ++ P     +P       P   A PP        A PL       +   
Sbjct: 689  ATPPSQAPPSLAAPPLQVPPSPPASPPMSPS--ATPPPQAPPPLAAPPLQVPPSPPASPP 746

Query: 312  SSAPGANNLQVNALVARLPLLLPRAPRSLIPPIPVS--PPILAPRLSSGALKV------- 362
             S       +V  L+A  PL +P +P + +P  P++  PP   P L++  L+        
Sbjct: 747  MSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPAS 806

Query: 363  ----------ATLPLSSRAGAPPAAVPIINMILPTVPALPGPGP---GPGRAP-PGGLTQ 408
                      A+LP+S  A  PP A P++   L  VP  P   P    P R P PG  T 
Sbjct: 807  FPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTS 866

Query: 409  PRGTENREVGIGGDQGPHDKGVKRTAEVPVSEASGQAPPAKAAKQDIEDTAS-------- 460
              G         G   P  +    T   P  + +G +  A +  +++    S        
Sbjct: 867  VSGPRLTLALAPGPPPPPSRSPSSTLSGP--DLAGHSSSATSTPEELRGYDSGPEGGAAA 924

Query: 461  ----DAKRKRGRPRKKSGGSGERNSTPLKSAAAMESAQSSRLPW-ETWGSGGEGNSAGGA 515
                DA+     P   S G     + PL    A   A  + LPW    G G         
Sbjct: 925  SPPPDAELAACHPAAWSRGP----APPL----AFRGAPGAPLPWPPATGPGSADGLCTIY 976

Query: 516  ERPGPMGEAEKGAVLAQGQGDGT-----VSKGGRGPGSQHTKEAE-DKIPLVPSKVSVIK 569
            E  GP         L  G   GT      +  G G  S+  K+A   ++PL   + SV++
Sbjct: 977  ETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQ 1036

Query: 570  GSRSQKEAFPLAKG 583
               S+      A+G
Sbjct: 1037 HLLSRTLLLAAAEG 1050



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 64/225 (28%), Positives = 85/225 (37%), Gaps = 38/225 (16%)

Query: 327 ARLP-LLLPRAPRSLIPPIPVSPPILAPRLSSGALKVATLPLSSRAGAPPAAVPIINMIL 385
           AR P LL PR P S  PP PV+P  L  R+   A  V   PL+ RAG    A        
Sbjct: 19  ARAPGLLTPRPPGSPRPPPPVTPAAL--RVLGAAGAVGRKPLAERAGGIGGA-------- 68

Query: 386 PTVPALPGPGPGPGRAPPGGLTQPRGTENREVGI---GGDQGPHDKGVKRTAEVPVS--- 439
            T+P           AP  G T+  GT +R          +G      K T+  PVS   
Sbjct: 69  -TIPE---------SAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPG 118

Query: 440 EASGQAPPA----KAAKQDIEDTASDAKRKRGRPRKKSGGSGERNST--PLKSAAAMESA 493
            ASG   P     K  +   E+T +  K     P++ +  +G R  T  P     +   A
Sbjct: 119 RASGTTRPGPLGQKGLRISAEETVARGKATEA-PKRSALSAGARRDTSGPTPGTPSPAMA 177

Query: 494 QSSRLPWETWGSGGEGNSAGGAERPGPMGEAEKGAVLAQGQGDGT 538
           + SR      G      SA    RP P  E  + +V +  +   T
Sbjct: 178 RRSRAAGTEVGLPRPAPSA----RPRPPTEGPRKSVSSASEHSTT 218



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 48/193 (24%), Positives = 71/193 (36%), Gaps = 19/193 (9%)

Query: 270 LENPEGGAHKKPERLAQPPKDLEARTGAGPLARGERKKSVVESSAPGANNLQVNALVARL 329
           L +P   A   P+    PP        A P  +     +V   S+P    L ++ L A  
Sbjct: 441 LTSPSRPASTPPD---SPPLQAPLSLPASPPLQTSLSPAVSPLSSP----LTIHPLQALS 493

Query: 330 PLLL--PRAPRS--LIPPIPVSPPILAPRLSSGALKVATLPLSS--RAGAPPAAVPIINM 383
            L    P+AP S  ++PP+     +  P L +    + T PL +      PP       +
Sbjct: 494 SLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPL 553

Query: 384 ILPTVPALPGPGPGPGRAPPGGLTQPRGTENREVGIGGDQGPHD------KGVKRTAEVP 437
             P +   P P P P +APP  LT P       +     Q P        +G+      P
Sbjct: 554 TTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSP 613

Query: 438 VSEASGQAPPAKA 450
           ++    QAPP  A
Sbjct: 614 LATPPPQAPPXLA 626



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 37/129 (28%), Positives = 49/129 (37%), Gaps = 19/129 (14%)

Query: 334 PRAPRSLIPPIPVSPPILAPRLSSGALKVATLPLSSRAGAPPAAVPIINMILPTVPALPG 393
           P  P S+  P P +PP LA     G   + + PLS  A  PP A P   + LP + A P 
Sbjct: 581 PETPSSIATPPPQAPPALASPPLQG---LPSPPLSPLATPPPQAPP--XLALPPLQAPPS 635

Query: 394 PGPGPGRAPPGGLTQPRGTENREVGIGGDQGPHDKGVKRTAEVPVSEAS----------- 442
           P   P  +P   L  P       + +   Q P         + P S  +           
Sbjct: 636 PPASPPLSP---LATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPP 692

Query: 443 GQAPPAKAA 451
            QAPP+ AA
Sbjct: 693 SQAPPSLAA 701



 Score = 38.5 bits (88), Expect = 0.018
 Identities = 50/179 (27%), Positives = 66/179 (36%), Gaps = 32/179 (17%)

Query: 251 LAEEDEHAPRERSSKPKNGLENPEGGA-----HKKPERLAQPPKDLEARTGAGPLARGER 305
           +A     AP   +S P  GL +P          + P  LA PP        A P      
Sbjct: 587 IATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASP------ 640

Query: 306 KKSVVESSAPGANN-LQVNALVA----------RLPLLLPRAPR---SLIPPIPVSPPIL 351
             S + + +P A N L V+ L A          + P   P +P    S  PP    P + 
Sbjct: 641 PLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLA 700

Query: 352 APRLSSGALKVATLPLSSRAGAPPAAVPIIN----MILPTVPALPGPGPG---PGRAPP 403
           AP L       A+ P+S  A  PP A P +      + P+ PA P   P    P R PP
Sbjct: 701 APPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPP 759



 Score = 38.1 bits (87), Expect = 0.024
 Identities = 57/223 (25%), Positives = 79/223 (35%), Gaps = 27/223 (12%)

Query: 251 LAEEDEHAPRERSSKPKNGLENPEGGAHKKP--ERLAQPPKDLEARTGAGPLARGERKKS 308
           ++   EH+  E S  P        GG  ++P    L+     L +   +GP ARG   ++
Sbjct: 209 VSSASEHSTTEPS--PAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGT-PRA 265

Query: 309 VVESSAPGANNLQV-------NALVARLPLLLPRAPRSLIPPIPVSP---PILAPRLSSG 358
               S P    LQ               P L P +   L  P P      P+  P  ++ 
Sbjct: 266 PAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAAT 325

Query: 359 ALKVATLPLSSRAGAPPAAVPIINMILPTVPALPG-PGPGPGRAPPGGLTQPRGTENREV 417
            L  ATLP S     P    P      P++  LP  P   P +APP   T P        
Sbjct: 326 PLP-ATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQ 384

Query: 418 GIGGDQGPHDKGVKRTAEVPVSEASGQAPPAKAAKQDIEDTAS 460
            I   Q PH           ++  S QAPP+  A   ++ T S
Sbjct: 385 TIPPIQVPHS----------LTSPSLQAPPSPLALSSLQATTS 417



 Score = 31.2 bits (69), Expect = 2.9
 Identities = 33/135 (24%), Positives = 46/135 (34%), Gaps = 10/135 (7%)

Query: 281 PERLAQPPKDLEARTGAGPLARGERKKSVVESSAPGANNLQVNALVARLPLLLPRAPRSL 340
           P  +A PP        + PL +G     +   + P     Q    +A  PL  P +P + 
Sbjct: 584 PSSIATPPPQAPPALASPPL-QGLPSPPLSPLATPPP---QAPPXLALPPLQAPPSPPAS 639

Query: 341 IP------PIPVSPPILAPRLSSGALKVATLPLSSRAGAPPAAVPIINMILPTVPALPGP 394
            P      P P +P  LA  L          P      +PPA+ P+     P   A P  
Sbjct: 640 PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSL 699

Query: 395 GPGPGRAPPGGLTQP 409
              P + PP     P
Sbjct: 700 AAPPLQVPPSPPASP 714


>gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Homo
           sapiens]
          Length = 305

 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 51/158 (32%), Positives = 63/158 (39%), Gaps = 14/158 (8%)

Query: 328 RLPLLLPRAPRSLIPPIPVSPPILAPRLSSGALKVATLPLSSRAGAPPAAVPIINMILPT 387
           +LP +   AP S  PP+PV  P  AP  +  A  VA  P++    AP  A        P 
Sbjct: 124 QLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAA-PVAVAVLAPAPAPAPAPAPAPA 182

Query: 388 VPALPGPGPGPGRAP-PGGLTQPRGTENREVGIGGDQGPHDKGVKRTAEVPVSEASGQAP 446
             A P P P P  AP P     P          G +QG   +G +  A+   S  SG+  
Sbjct: 183 PVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQG--QRGQEPLADQLHSGISGRPA 240

Query: 447 PAKAA--------KQDIEDTASD--AKRKRGRPRKKSG 474
              AA        K+      SD  AKRKR  P K SG
Sbjct: 241 AGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSG 278


>gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Homo
           sapiens]
          Length = 305

 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 51/158 (32%), Positives = 63/158 (39%), Gaps = 14/158 (8%)

Query: 328 RLPLLLPRAPRSLIPPIPVSPPILAPRLSSGALKVATLPLSSRAGAPPAAVPIINMILPT 387
           +LP +   AP S  PP+PV  P  AP  +  A  VA  P++    AP  A        P 
Sbjct: 124 QLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAA-PVAVAVLAPAPAPAPAPAPAPA 182

Query: 388 VPALPGPGPGPGRAP-PGGLTQPRGTENREVGIGGDQGPHDKGVKRTAEVPVSEASGQAP 446
             A P P P P  AP P     P          G +QG   +G +  A+   S  SG+  
Sbjct: 183 PVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQG--QRGQEPLADQLHSGISGRPA 240

Query: 447 PAKAA--------KQDIEDTASD--AKRKRGRPRKKSG 474
              AA        K+      SD  AKRKR  P K SG
Sbjct: 241 AGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSG 278


>gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo
           sapiens]
          Length = 316

 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 51/158 (32%), Positives = 63/158 (39%), Gaps = 14/158 (8%)

Query: 328 RLPLLLPRAPRSLIPPIPVSPPILAPRLSSGALKVATLPLSSRAGAPPAAVPIINMILPT 387
           +LP +   AP S  PP+PV  P  AP  +  A  VA  P++    AP  A        P 
Sbjct: 135 QLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAA-PVAVAVLAPAPAPAPAPAPAPA 193

Query: 388 VPALPGPGPGPGRAP-PGGLTQPRGTENREVGIGGDQGPHDKGVKRTAEVPVSEASGQAP 446
             A P P P P  AP P     P          G +QG   +G +  A+   S  SG+  
Sbjct: 194 PVAAPAPAPAPAPAPAPAPAPAPDAAPQESAEQGANQG--QRGQEPLADQLHSGISGRPA 251

Query: 447 PAKAA--------KQDIEDTASD--AKRKRGRPRKKSG 474
              AA        K+      SD  AKRKR  P K SG
Sbjct: 252 AGTAAASANGAAIKKLSGPLISDFFAKRKRSAPEKSSG 289


>gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens]
          Length = 1499

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 48/188 (25%), Positives = 71/188 (37%), Gaps = 27/188 (14%)

Query: 263  SSKPKNGLENPEGGAHKKPER-LAQPPKDLEARTGAGPLARGERKKSVVESSAPGANNL- 320
            S  P     NP G  H  P R L + P DL                S+ +  +PG  +L 
Sbjct: 888  SHMPLPPASNPPGTVHSAPNRGLGRRPSDLTI--------------SINQMGSPGMGHLK 933

Query: 321  -----QVNALVARLP---LLLPRAPRSLIPPIPVSPP--ILAPRLSSGALKVATLPLS-S 369
                 QV++ +   P   L  P+ P  ++P    +PP  + +P++   +L V +   S S
Sbjct: 934  SPTLSQVHSPLVTSPSANLKSPQTPSQMVPLPSANPPGPLKSPQVLGSSLSVRSPTGSPS 993

Query: 370  RAGAPPAAVPIINMILPTVPALPGPGPGPGRAPPGGLTQPRGTENREVGIGGDQGPHDKG 429
            R  +P  AVP    +     A+P PG    + PP  +       N E G     GP    
Sbjct: 994  RLKSPSMAVPSPGWVASPKTAMPSPGVSQNKQPPLNMNSSTTLSNMEQGTLPPSGPRSSS 1053

Query: 430  VKRTAEVP 437
                A  P
Sbjct: 1054 SAPPANPP 1061



 Score = 30.8 bits (68), Expect = 3.8
 Identities = 22/67 (32%), Positives = 28/67 (41%), Gaps = 19/67 (28%)

Query: 337 PRSLIPPIPVSPPILAPRLSSGALKVATLPLSSRAGAPPAAVPIINMILPTVPALPGPGP 396
           PR+ +   P  PP   P           LPLS+ +   P + P      P +P  P P P
Sbjct: 272 PRAKLDQAPKVPPTPEP-----------LPLSTPSAGTPQSQP------PPLP--PPPPP 312

Query: 397 GPGRAPP 403
            PG APP
Sbjct: 313 APGSAPP 319



 Score = 30.4 bits (67), Expect = 5.0
 Identities = 80/369 (21%), Positives = 121/369 (32%), Gaps = 38/369 (10%)

Query: 264  SKPKNGLENPEGGAHKKPERLAQPPKDLEARTGAGPLARGERKKSVVESS--APGANNLQ 321
            + PK  + +P    +K      QPP ++ + T    + +G    S   SS  AP AN   
Sbjct: 1009 ASPKTAMPSPGVSQNK------QPPLNMNSSTTLSNMEQGTLPPSGPRSSSSAPPANPPS 1062

Query: 322  VNALVARLPLLLPRAPRSLIP-PIPVSPPI--LAPRLSSGALKVATLPLSSRAGAPPAAV 378
                     L+ P  P +  P P P   P+  +  ++S  A+  +T PL   A    A  
Sbjct: 1063 --------GLMNPSLPFTSSPDPTPSQNPLSLMMTQMSKYAMPSST-PLYHNAIKTIATS 1113

Query: 379  PIINMILPTVPALPGPGPGPGRAPPGGLTQPRGTENREVGIGGDQGPHDKGVKRTAEVPV 438
               + +LP  P LP P P  G  P    +QP              G +  G +  +  P 
Sbjct: 1114 D--DELLPDRPLLPPPPPPQGSGPGISNSQPSQMHLNSAAAQSPMGMNLPGQQPLSHEP- 1170

Query: 439  SEASGQAPPAKAAKQDIEDTASDAKRKRGRPRKKSGGSGERNSTPLKSAAAMESAQSSRL 498
              A   +P    +   +   A       G P + S          L +      + S  +
Sbjct: 1171 PPAMLPSPTPLGSNIPLHPNAQGT----GGPPQNSMMMAPGGPDSLNAPCGPVPSSSQMM 1226

Query: 499  PWE---TWGSGGEGNSAGGAERPGPMGEAEKGAVL----AQGQGDGTVSKGGRGPGSQHT 551
            P+        G    + GG   PG       G  L       Q  G +       G    
Sbjct: 1227 PFPPRLQQPHGAMAPTGGGGGGPGLQQHYPSGMALPPEDLPNQPPGPMPPQQHLMGKAMA 1286

Query: 552  KEAEDKIP--LVPSKVSVIKGSRSQKEAFPLAKG--EVDTAPQGNKDLKEHVLQSSLSQE 607
                D  P  ++P   SV+      +   P   G  E D +     +     LQ     E
Sbjct: 1287 GRMGDAYPPGVLPGVASVLNDPELSEVIRPTPTGIPEFDLSRIIPSEKPSSTLQYFPKSE 1346

Query: 608  HKDPKATPP 616
            ++ PKA PP
Sbjct: 1347 NQPPKAQPP 1355


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 81/326 (24%), Positives = 110/326 (33%), Gaps = 38/326 (11%)

Query: 281 PERLAQPPKDLEARTGAGPLARGERKKSVVESSAPGANNLQVNALVARLPLLLPRAPRSL 340
           P  LA PP  +     A P                 A  LQ+     + P  L   P   
Sbjct: 471 PPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQA 530

Query: 341 IPPIPVSPPILAPRLSSGALKVATLPLSSRAGAPPAAVPIINMILPTVPALPGPGP---G 397
           +P  P S P  AP   S     A+LP+S  A  PP A P++   L  VP  P   P    
Sbjct: 531 LPSPPASFPGQAPFSPS-----ASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA 585

Query: 398 PGRAP-PGGLTQPRGTENREVGIGGDQGPHDKGVKRTAEVPVSEASGQAPPAKAAKQDIE 456
           P R P PG  T   G         G   P  +    T   P  + +G +  A +  +++ 
Sbjct: 586 PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP--DLAGHSSSATSTPEELR 643

Query: 457 DTAS------------DAKRKRGRPRKKSGGSGERNSTPLKSAAAMESAQSSRLPW-ETW 503
              S            DA+     P   S G     + PL    A   A  + LPW    
Sbjct: 644 GYDSGPEGGAAASPPPDAELAACHPAAWSRGP----APPL----AFRGAPGAPLPWPPAT 695

Query: 504 GSGGEGNSAGGAERPGPMGEAEKGAVLAQGQGDGT-----VSKGGRGPGSQHTKEAE-DK 557
           G G         E  GP         L  G   GT      +  G G  S+  K+A   +
Sbjct: 696 GPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGE 755

Query: 558 IPLVPSKVSVIKGSRSQKEAFPLAKG 583
           +PL   + SV++   S+      A+G
Sbjct: 756 LPLGALQASVVQHLLSRTLLLAAAEG 781



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 64/225 (28%), Positives = 85/225 (37%), Gaps = 38/225 (16%)

Query: 327 ARLP-LLLPRAPRSLIPPIPVSPPILAPRLSSGALKVATLPLSSRAGAPPAAVPIINMIL 385
           AR P LL PR P S  PP PV+P  L  R+   A  V   PL+ RAG    A        
Sbjct: 19  ARAPGLLTPRPPGSPRPPPPVTPAAL--RVLGAAGAVGRKPLAERAGGIGGA-------- 68

Query: 386 PTVPALPGPGPGPGRAPPGGLTQPRGTENREVGI---GGDQGPHDKGVKRTAEVPVS--- 439
            T+P           AP  G T+  GT +R          +G      K T+  PVS   
Sbjct: 69  -TIPE---------SAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPG 118

Query: 440 EASGQAPPA----KAAKQDIEDTASDAKRKRGRPRKKSGGSGERNST--PLKSAAAMESA 493
            ASG   P     K  +   E+T +  K     P++ +  +G R  T  P     +   A
Sbjct: 119 RASGTTRPGPLGQKGLRISAEETVARGKATEA-PKRSALSAGARRDTSGPTPGTPSPAMA 177

Query: 494 QSSRLPWETWGSGGEGNSAGGAERPGPMGEAEKGAVLAQGQGDGT 538
           + SR      G      SA    RP P  E  + +V +  +   T
Sbjct: 178 RRSRAAGTEVGLPRPAPSA----RPRPPTEGPRKSVSSASEHSTT 218



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 62/230 (26%), Positives = 82/230 (35%), Gaps = 65/230 (28%)

Query: 264 SKPKNGLENPEGGAHKKPERLAQPPKDLEARTGAGPLARGERKKSVVESSAPGANNLQVN 323
           S+PK     P+G    +P ++  P KD  A    GPL           SS+P A      
Sbjct: 270 SQPK-----PKGLQALRPPQVTPPRKD--AAPALGPL-----------SSSPLATPSPSA 311

Query: 324 ALVARLPLLLPRAPRS------------LIPPIPVSPPILA---------PRLSSGALKV 362
           AL ++ P  LP  P S            L PP P +PP L          P  ++ +L  
Sbjct: 312 ALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGS 371

Query: 363 ATL----------PLSSRAGAPPAAVPIINMILPTVPALPGPGPGPGRAPPGGLTQPRGT 412
            TL          PLS  A  PP A P   + LP + A P P   P  +P   L  P   
Sbjct: 372 PTLQATHSFLPSPPLSPLATPPPQAPPA--LALPPLQAPPSPPASPPLSP---LATPSPQ 426

Query: 413 ENREVGIGGDQGPHDKGVKRTAEVPVSEAS-----------GQAPPAKAA 451
               + +   Q P         + P S  +            QAPP+ AA
Sbjct: 427 APNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAA 476



 Score = 35.0 bits (79), Expect = 0.20
 Identities = 56/202 (27%), Positives = 70/202 (34%), Gaps = 30/202 (14%)

Query: 264 SKPKNGLENPEGGAHKKPERLAQPPKDLEARTGAGPLARGERKKSVVESSAPGANN-LQV 322
           S P + L  P   A   P  LA PP        A P        S + + +P A N L V
Sbjct: 383 SPPLSPLATPPPQA---PPALALPPLQAPPSPPASP------PLSPLATPSPQAPNALAV 433

Query: 323 NALVA----------RLPLLLPRAPR---SLIPPIPVSPPILAPRLSSGALKVATLPLSS 369
           + L A          + P   P +P    S  PP    P + AP L       A+ P+S 
Sbjct: 434 HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP 493

Query: 370 RAGAPPAAVPIINMILPTVPALPGPGPGPGRAPPGGLTQPRGTENREVGIGGDQGPHDKG 429
            A  PP A P +       P L    P P +APP   T P             Q P    
Sbjct: 494 SATPPPQAPPPL-----AAPPLQLAKP-PPQAPPALATPPLQALPSPPASFPGQAPFSPS 547

Query: 430 VKRTAEVPVSEASGQAPPAKAA 451
                  P++    QAPP  AA
Sbjct: 548 ASLPMS-PLATPPPQAPPVLAA 568


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 81/326 (24%), Positives = 110/326 (33%), Gaps = 38/326 (11%)

Query: 281 PERLAQPPKDLEARTGAGPLARGERKKSVVESSAPGANNLQVNALVARLPLLLPRAPRSL 340
           P  LA PP  +     A P                 A  LQ+     + P  L   P   
Sbjct: 432 PPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQA 491

Query: 341 IPPIPVSPPILAPRLSSGALKVATLPLSSRAGAPPAAVPIINMILPTVPALPGPGP---G 397
           +P  P S P  AP   S     A+LP+S  A  PP A P++   L  VP  P   P    
Sbjct: 492 LPSPPASFPGQAPFSPS-----ASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA 546

Query: 398 PGRAP-PGGLTQPRGTENREVGIGGDQGPHDKGVKRTAEVPVSEASGQAPPAKAAKQDIE 456
           P R P PG  T   G         G   P  +    T   P  + +G +  A +  +++ 
Sbjct: 547 PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP--DLAGHSSSATSTPEELR 604

Query: 457 DTAS------------DAKRKRGRPRKKSGGSGERNSTPLKSAAAMESAQSSRLPW-ETW 503
              S            DA+     P   S G     + PL    A   A  + LPW    
Sbjct: 605 GYDSGPEGGAAASPPPDAELAACHPAAWSRGP----APPL----AFRGAPGAPLPWPPAT 656

Query: 504 GSGGEGNSAGGAERPGPMGEAEKGAVLAQGQGDGT-----VSKGGRGPGSQHTKEAE-DK 557
           G G         E  GP         L  G   GT      +  G G  S+  K+A   +
Sbjct: 657 GPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGE 716

Query: 558 IPLVPSKVSVIKGSRSQKEAFPLAKG 583
           +PL   + SV++   S+      A+G
Sbjct: 717 LPLGALQASVVQHLLSRTLLLAAAEG 742



 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 84/317 (26%), Positives = 117/317 (36%), Gaps = 39/317 (12%)

Query: 327 ARLP-LLLPRAPRSLIPPIPVSPPILAPRLSSGALKVATLPLSSRAG-----APPAAVPI 380
           AR P LL PR P S  PP PV+P  L  R+   A  V   PL+ RAG       P + P 
Sbjct: 19  ARAPGLLTPRPPGSPRPPPPVTPAAL--RVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76

Query: 381 INMILPTVPALPGPGPGPG-RAPPGGLTQP-------RGTENREVGIGGDQGPHDKGVKR 432
                PT  + P P  G G RAPP   T P       R +     G  G +G      + 
Sbjct: 77  AG---PTRTSRP-PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEET 132

Query: 433 TAEVPVSEASGQAPPAKAAKQDIE----DTASDAKRKRGRPRKKSGG-----SGERNSTP 483
            A    +EA  ++  +  A++D       T S A  +R R      G        R   P
Sbjct: 133 VARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPP 192

Query: 484 LKSAAAMESAQSSRLPWETWGSGGEGNSAGGA-ERPGPMGEAEKGAVLAQGQGDGTVSKG 542
            +      S+ S     E   +     SAGG  +RP     +     L+     G  ++G
Sbjct: 193 TEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARG 252

Query: 543 -GRGPGSQHTKEAEDKIPLVPSKVSVIKGSRSQKEAFPLAKGEVDTAPQGNKDLKEHVLQ 601
             R P      + +    L P +V     +  +K+A P A G + ++P            
Sbjct: 253 TPRAPAHPSQPKPKGLQALRPPQV-----TPPRKDAAP-ALGPLSSSPLATPSPSAPPSP 306

Query: 602 SS--LSQEHKDPKATPP 616
           S+    Q    P ATPP
Sbjct: 307 SAPPSLQTLPSPPATPP 323



 Score = 37.7 bits (86), Expect = 0.031
 Identities = 55/198 (27%), Positives = 73/198 (36%), Gaps = 34/198 (17%)

Query: 276 GAHKKPERLAQP-PKDLEARTGAGPLARGERKKSVVESSAPGANNLQVNALVARLPLL-- 332
           G  + P   +QP PK L+A     P     RK      +AP    L  + L    P    
Sbjct: 252 GTPRAPAHPSQPKPKGLQALRP--PQVTPPRK-----DAAPALGPLSSSPLATPSPSAPP 304

Query: 333 LPRAPRSL--IPPIPVSPPILA------PRLSSGALKVATLPLSSRAGAPPAAVPIINMI 384
            P AP SL  +P  P +PP  A      P L +    + + PLS  A  PP A P   + 
Sbjct: 305 SPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPA--LA 362

Query: 385 LPTVPALPGPGPGPGRAPPGGLTQPRGTENREVGIGGDQGPHDKGVKRTAEVPVSEAS-- 442
           LP + A P P   P  +P   L  P       + +   Q P         + P S  +  
Sbjct: 363 LPPLQAPPSPPASPPLSP---LATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 419

Query: 443 ---------GQAPPAKAA 451
                     QAPP+ AA
Sbjct: 420 PVSPSATPPSQAPPSLAA 437



 Score = 35.0 bits (79), Expect = 0.20
 Identities = 56/202 (27%), Positives = 70/202 (34%), Gaps = 30/202 (14%)

Query: 264 SKPKNGLENPEGGAHKKPERLAQPPKDLEARTGAGPLARGERKKSVVESSAPGANN-LQV 322
           S P + L  P   A   P  LA PP        A P        S + + +P A N L V
Sbjct: 344 SPPLSPLATPPPQA---PPALALPPLQAPPSPPASP------PLSPLATPSPQAPNALAV 394

Query: 323 NALVA----------RLPLLLPRAPR---SLIPPIPVSPPILAPRLSSGALKVATLPLSS 369
           + L A          + P   P +P    S  PP    P + AP L       A+ P+S 
Sbjct: 395 HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP 454

Query: 370 RAGAPPAAVPIINMILPTVPALPGPGPGPGRAPPGGLTQPRGTENREVGIGGDQGPHDKG 429
            A  PP A P +       P L    P P +APP   T P             Q P    
Sbjct: 455 SATPPPQAPPPL-----AAPPLQLAKP-PPQAPPALATPPLQALPSPPASFPGQAPFSPS 508

Query: 430 VKRTAEVPVSEASGQAPPAKAA 451
                  P++    QAPP  AA
Sbjct: 509 ASLPMS-PLATPPPQAPPVLAA 529


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 60/206 (29%), Positives = 77/206 (37%), Gaps = 39/206 (18%)

Query: 278 HKKPERLAQPPKDLEART------GAGPLARGERKKSVVESSAPGANNLQVNALVARLPL 331
           H +P +  QPP   +  +      G GP A G        SSAP A      A     P 
Sbjct: 90  HPQPHQQQQPPPPPQDSSKPVVAQGPGP-APGVGSAPPASSSAPPATPPTSGAPPGSGPG 148

Query: 332 LLPRAPRSLIPPIPVSPPILAPRLSSGALKVATLPLSSRAGAPPAAVPIINMILPTVPAL 391
             P  P ++    P +PP   P  SSG   V T P   +AG PP          P   A+
Sbjct: 149 PTPTPPPAVTSAPPGAPPPTPP--SSG---VPTTP--PQAGGPP----------PPPAAV 191

Query: 392 PGPGPGPGRAP----------PGGLTQPRGTENREVGIGGDQGPHDKGVK----RTAEVP 437
           PGPGPGP + P          PGG  +P G        G  + PH  G +    R    P
Sbjct: 192 PGPGPGPKQGPGPGGPKGGKMPGG-PKPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHPP 250

Query: 438 VSEASGQAPPAKAAKQDIEDTASDAK 463
             +   Q PP        E+  SD++
Sbjct: 251 YHQQHHQGPPPGGPGGRSEEKISDSE 276


>gi|18079216 CASK interacting protein 1 [Homo sapiens]
          Length = 1431

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 59/232 (25%), Positives = 87/232 (37%), Gaps = 37/232 (15%)

Query: 281  PERLAQPPKDLEARTGAGPLARGERKKSVVESSAPGANNLQVNALVARLPLLLPRAPRSL 340
            P     PP DL A     P   GE +K      +P              P+L    P+  
Sbjct: 1195 PPPAEPPPTDL-AHLPPLPPPEGEARKPAKPPVSPK-------------PVLTQPVPKLQ 1240

Query: 341  IPPIPVSPPILAPRLSSGALKVA---TLPLSSRAGAPPAAVPIINMI--LPTVPALPGPG 395
              P P S  +  P   S  +K A     P+S +   PP A   +  +  LP+  A P P 
Sbjct: 1241 GSPTPTSKKVPLPGPGSPEVKRAHGTPPPVSPKPPPPPTAPKPVKAVAGLPSGSAGPSPA 1300

Query: 396  PGPGRAPPGGLTQPRGTENREVGIGGDQGPHD---------KGVKRTAEVPVSEASGQAP 446
            P P R PP  L +P GT    +G    + P           K  +  A    + A+  AP
Sbjct: 1301 PSPARQPPAALAKPPGTP-PSLGASPAKPPSPGAPALHVPAKPPRAAAAAAAAAAAPPAP 1359

Query: 447  PAKA-----AKQDIEDTA---SDAKRKRGRPRKKSGGSGERNSTPLKSAAAM 490
            P  A     A+Q +E+T+   + A +      ++    G R+S   KS  ++
Sbjct: 1360 PEGASPGDSARQKLEETSACLAAALQAVEEKIRQEDAQGPRDSAAEKSTGSI 1411


>gi|56549668 AT rich interactive domain 2 (ARID, RFX-like) [Homo
           sapiens]
          Length = 1835

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 31/127 (24%), Positives = 58/127 (45%), Gaps = 16/127 (12%)

Query: 81  PSTLSNEEYMYAYRWIRNHLEEHTDTCLPKQSVYDAYRKYCESLACCRPLSTANFGKIIR 140
           P  +  +   +A +W+  H E + D  + +  +Y  Y   C  LA    L++  F K +R
Sbjct: 513 PGIVEIDSEKFACQWLNAHFEVNPDCSVSRAEMYSEYLSTCSKLARGGILTSTGFYKCLR 572

Query: 141 EIFPDIKARRL---GGRGQSKYCYSGIRRKTLVSMPPLPGLDLKGSESP--------EMG 189
            +FP+   +R+      GQ+     G++R+ +    PLP + +   + P        +  
Sbjct: 573 TVFPNHTVKRVEDSSSNGQAHIHVVGVKRRAI----PLP-IQMYYQQQPVSTSVVRVDSV 627

Query: 190 PEVTPAP 196
           P+V+PAP
Sbjct: 628 PDVSPAP 634


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
           sapiens]
          Length = 699

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 77/348 (22%), Positives = 125/348 (35%), Gaps = 42/348 (12%)

Query: 252 AEEDEHAPRERSSKPKNGLENPEGGAHKKPERLAQPPKDLEARTGAGPLARGERKKSVVE 311
           +   E +  +   + K  ++N  G     P   A PPK      G  P  +   K+  VE
Sbjct: 264 SSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKK---SLGTQPPKKAVEKQQPVE 320

Query: 312 SSAPGANNLQVNALVARLPLLLPRAPRSLIPPIPVSPPILAPRLSSGALKVATLPLSSRA 371
           SS   ++    ++   + P       ++   P    PP      SS     +       A
Sbjct: 321 SSEDSSDESDSSSEEEKKPPTKAVVSKATTKP----PPAKKAAESSSDSSDSDSSEDDEA 376

Query: 372 GAPPAAVPIINMILPTV----PALPGPGPGPGRAPPGG---LTQPRGTENREVGIGGDQG 424
            + PA     +   P V    PA+  P   P +   GG   LT+   + + E      + 
Sbjct: 377 PSKPAGTTKNSSNKPAVTTKSPAVK-PAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEE 435

Query: 425 PHDKGVKRTAEVPVSEASGQAPPAKAAKQDIEDTASDAKRK--------------RGRPR 470
              K +  T +   +  +  + PAK A Q   D++SD+                 + +P+
Sbjct: 436 EKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQ 495

Query: 471 KKSGGSGERNSTPLKSAAAME-SAQSSRLPWETWGSGGEGNSAGGAERPGPMGEAEKGAV 529
           K +GG     + P K A+A +  A+SS        S  + +S    E+    G     A 
Sbjct: 496 KVAGG-----AAPSKPASAKKGKAESSN------SSSSDDSSEEEEEKLKGKGSPRPQAP 544

Query: 530 LAQGQGDGTVSKGGRGPGSQHTKEAEDKIPLVPSKVSVIKGSRSQKEA 577
            A G    T   G     S+  +E + K  +V SK   +K  R Q EA
Sbjct: 545 KANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLK-KRKQNEA 591



 Score = 37.0 bits (84), Expect = 0.054
 Identities = 35/133 (26%), Positives = 53/133 (39%), Gaps = 16/133 (12%)

Query: 432 RTAEVPVSEASGQAPPAKAAKQ-----DIEDTASDAKRKRGRPRKKSGGSGERNSTPLKS 486
           ++A+VP  +     P AK AK+     D ED++ + +  +G P KK+    +R   P   
Sbjct: 59  KSAKVPERKLQANGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGK 118

Query: 487 AAAMESAQSSRLPWETWGSGGEGNSAGGAERPGPMGEAEKGAVLAQGQGDGTVSKGGRGP 546
           AAA  S  SS           E +S    E        +KG V  Q +      K  +  
Sbjct: 119 AAAKASESSS----------SEESSDDDDEEDQKKQPVQKG-VKPQAKAAKAPPKKAKSS 167

Query: 547 GSQHTKEAEDKIP 559
            S     +ED+ P
Sbjct: 168 DSDSDSSSEDEPP 180


>gi|116734704 interferon regulatory factor 2 binding protein 2
           isoform A [Homo sapiens]
          Length = 587

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 81/336 (24%), Positives = 112/336 (33%), Gaps = 76/336 (22%)

Query: 270 LENPEGGAHKKPERLAQPPKDLEARTGAGPLARGERKKSVVESSAPGANNLQVNALVARL 329
           L+  +   H  PE   + P+ LE    A    R  R  S   SS P A+  Q        
Sbjct: 93  LQQQQQLGHGGPEAAPRAPQALERYPLAAAAERPPRLGSDFGSSRPAASLAQ-------- 144

Query: 330 PLLLPRAPRSLIPPIPVSPPILAPRLSSGALKVATLPLSSRAG--------APPAAVPII 381
                       PP P  PP+    + +G  K+   P  +R           PP  VP++
Sbjct: 145 ------------PPTPQPPPVNGILVPNGFSKLEEPPELNRQSPNPRRGHAVPPTLVPLM 192

Query: 382 NMILPTVPALPGPGPGPGRAPPGGLTQPRGTENREVGIGG--DQGPHDKGVKRTAEVPVS 439
           N     +P   G G   GRA    L    GT    +G     D G H +    ++   V 
Sbjct: 193 NGSATPLPTALGLG---GRAA-ASLAAVSGTAAASLGSAQPTDLGAHKRPASVSSSAAVE 248

Query: 440 EASGQA--------PPAKAAKQDIEDTASDAKRKRGRPRKKSGGSGER------------ 479
               +A        PPA     D   TA+ A         KS GSGE+            
Sbjct: 249 HEQREAAAKEKQPPPPAHRGPADSLSTAAGAAELSAEGAGKSRGSGEQDWVNRPKTVRDT 308

Query: 480 --------NSTPLKSAAAMESAQSS--RLPWETWGSGGEGNSAGGA--ERPGPMGEAEKG 527
                   +S P +S    E A ++   L +E  G+ G    A  A   +P P  E E G
Sbjct: 309 LLALHQHGHSGPFESKFKKEPALTAGRLLGFEANGANGSKAVARTARKRKPSPEPEGEVG 368

Query: 528 AVLAQGQGDGTVSKGGRGPGSQHTKEAEDKIPLVPS 563
                G+    +S    G           KIP+ P+
Sbjct: 369 PPKINGEAQPWLSTSTEGL----------KIPMTPT 394


>gi|157785645 SPEG complex locus [Homo sapiens]
          Length = 3267

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 70/272 (25%), Positives = 107/272 (39%), Gaps = 37/272 (13%)

Query: 274 EGGAHKKPERLAQPPKDLEARTGAGP-------LARGERKKSVVESSAPGANNLQVNALV 326
           E G+     RL   P+  +A TGAGP       L R  R  ++V +S    ++L V + +
Sbjct: 198 EAGSGGGTRRLPGSPRQAQA-TGAGPRHLGVEPLVRASRA-NLVGASWGSEDSLSVASDL 255

Query: 327 ARLPLLLPRAPR-SLIPPIPVS-----PPILAPRLSSGALKVATLPLSSRAGAPPAAVPI 380
                 L R    S+   +P S      P L P+L+S A +    P  S++   P   P 
Sbjct: 256 YGSAFSLYRGRALSIHVSVPQSGLRREEPDLQPQLASEAPRRPAQPPPSKSALLPPPSPR 315

Query: 381 INMILPTVPALPGPGPGPGRAPPGG--------LTQPRGTENREVGIGGDQGPHDKGVKR 432
           +    P     PGP   P   P           L +   TE +        GP   G   
Sbjct: 316 VGKRSP-----PGPPAQPAATPTSPHRRTQEPVLPEDTTTEEKRGKKSKSSGPSLAGTAE 370

Query: 433 TA-EVPVSEASGQAPP-------AKAAKQDIEDTASDAKRKRGRPRKKSGGSGERNSTPL 484
           +  + P+SEASG+           +A  + ++      +R+R   R  S  +  R   PL
Sbjct: 371 SRPQTPLSEASGRLSALGRSPRLVRAGSRILDKLQFFEERRRSLERSDSPPAPLRPWVPL 430

Query: 485 KSAAAMESAQSSR-LPWETWGSGGEGNSAGGA 515
           + A ++E  +S R  PW T G+  E   A G+
Sbjct: 431 RKARSLEQPKSERGAPWGTPGASQEELRAPGS 462



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 68/291 (23%), Positives = 107/291 (36%), Gaps = 52/291 (17%)

Query: 250 GLAEEDEHAPRERSSKPKNGLENPEGGAHKKPERLAQPPKDLEARTGA--GPLARGERKK 307
           G ++E+  AP   + + +  L   +  +  +  R   P  DLE R     G + R   ++
Sbjct: 451 GASQEELRAPGSVAERRR--LFQQKAASLDERTRQRSPASDLELRFAQELGRIRRSTSRE 508

Query: 308 SVVESSAPGANNLQVNALVARLPLLLPRAPRSLIPPIPVSPPILAPRLSSGALKVATLPL 367
            +V S                L   L RAP    P  P  PP+ +           + P 
Sbjct: 509 ELVRSHES-------------LRATLQRAPS---PREPGEPPLFSR---------PSTPK 543

Query: 368 SSRAGAPPAAVPIINMILPTVPALPGPGPGPGRAP---PGGLTQPRGTENREVGIGGDQG 424
           +SRA +P AA P      P+  +   PG  PGR     P G T+P     +EV    DQ 
Sbjct: 544 TSRAVSPAAAQP------PSPSSAEKPGDEPGRPRSRGPAGRTEPGEGPQQEVR-RRDQF 596

Query: 425 PHDKGVKRTAEVPVSEASGQAPPAKAAKQDIEDTASDAKRKRGRPRKKSGGSGERNSTPL 484
           P       T    + E     PP  A   +    A   +++   P  ++       +  L
Sbjct: 597 P------LTRSRAIQECRSPVPPPAADPPEARTKAPPGRKRE--PPAQAVRFLPWATPGL 648

Query: 485 KSAAAMESAQSSRLPWETWGSGGEGNSAGGAERPGPMGEAEKGAVLAQGQG 535
           + AA  ++ + +R      G   E     G E  GP G  ++    +QG+G
Sbjct: 649 EGAAVPQTLEKNRA-----GPEAEKRLRRGPEEDGPWGPWDRRGARSQGKG 694


>gi|7669528 neuregulin 2 isoform 2 [Homo sapiens]
          Length = 844

 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 61/244 (25%), Positives = 88/244 (36%), Gaps = 26/244 (10%)

Query: 364 TLPLSSRAGAPPAAVPIINMILPTVPAL-----PGPGPGPGRAPPGGLTQPRGTENREVG 418
           T P S+ A + P A PI   +    P L     PGPGPGPG  P  G    R  ++    
Sbjct: 615 TSPNSAHAVSLPPAAPISYRLAEQQPLLRHPAPPGPGPGPGPGPGPGADMQRSYDSYYYP 674

Query: 419 IGGDQGPHDKGVKRTAEVPVSEASGQAPPAKAAKQDIEDTASDA-------KRKRGRPRK 471
             G  GP     + T  +  S  S  A P +  + D  +T  +         R RG  R+
Sbjct: 675 AAG-PGPR----RGTCALGGSLGSLPASPFRIPEDDEYETTQECAPPPPPRPRARGASRR 729

Query: 472 KSGGSGERNSTPLKSAAAMESAQSSRLPWETWGSGGEGNSAGGAERPGPMGEAEKGAVLA 531
            S G      + L   AA  +  +      + GSGG     G A       +   GA+ A
Sbjct: 730 TSAGPRRWRRSRLNGLAAQRARAARDSLSLSSGSGG-----GSASASDDDADDADGALAA 784

Query: 532 QGQGDGTVSKGGRGPGSQHTKEAEDKIPLVPSKVSVIKGSRSQKEAFPLAKGEVDTAPQG 591
               + T   G RG       ++    P   S+      S S + +   ++G    A Q 
Sbjct: 785 ----ESTPFLGLRGAHDALRSDSPPLCPAADSRTYYSLDSHSTRASSRHSRGPPPRAKQD 840

Query: 592 NKDL 595
           +  L
Sbjct: 841 SAPL 844


>gi|7669532 neuregulin 2 isoform 4 [Homo sapiens]
          Length = 852

 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 61/244 (25%), Positives = 88/244 (36%), Gaps = 26/244 (10%)

Query: 364 TLPLSSRAGAPPAAVPIINMILPTVPAL-----PGPGPGPGRAPPGGLTQPRGTENREVG 418
           T P S+ A + P A PI   +    P L     PGPGPGPG  P  G    R  ++    
Sbjct: 623 TSPNSAHAVSLPPAAPISYRLAEQQPLLRHPAPPGPGPGPGPGPGPGADMQRSYDSYYYP 682

Query: 419 IGGDQGPHDKGVKRTAEVPVSEASGQAPPAKAAKQDIEDTASDA-------KRKRGRPRK 471
             G  GP     + T  +  S  S  A P +  + D  +T  +         R RG  R+
Sbjct: 683 AAG-PGPR----RGTCALGGSLGSLPASPFRIPEDDEYETTQECAPPPPPRPRARGASRR 737

Query: 472 KSGGSGERNSTPLKSAAAMESAQSSRLPWETWGSGGEGNSAGGAERPGPMGEAEKGAVLA 531
            S G      + L   AA  +  +      + GSGG     G A       +   GA+ A
Sbjct: 738 TSAGPRRWRRSRLNGLAAQRARAARDSLSLSSGSGG-----GSASASDDDADDADGALAA 792

Query: 532 QGQGDGTVSKGGRGPGSQHTKEAEDKIPLVPSKVSVIKGSRSQKEAFPLAKGEVDTAPQG 591
               + T   G RG       ++    P   S+      S S + +   ++G    A Q 
Sbjct: 793 ----ESTPFLGLRGAHDALRSDSPPLCPAADSRTYYSLDSHSTRASSRHSRGPPPRAKQD 848

Query: 592 NKDL 595
           +  L
Sbjct: 849 SAPL 852


>gi|7669530 neuregulin 2 isoform 3 [Homo sapiens]
          Length = 858

 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 61/244 (25%), Positives = 88/244 (36%), Gaps = 26/244 (10%)

Query: 364 TLPLSSRAGAPPAAVPIINMILPTVPAL-----PGPGPGPGRAPPGGLTQPRGTENREVG 418
           T P S+ A + P A PI   +    P L     PGPGPGPG  P  G    R  ++    
Sbjct: 629 TSPNSAHAVSLPPAAPISYRLAEQQPLLRHPAPPGPGPGPGPGPGPGADMQRSYDSYYYP 688

Query: 419 IGGDQGPHDKGVKRTAEVPVSEASGQAPPAKAAKQDIEDTASDA-------KRKRGRPRK 471
             G  GP     + T  +  S  S  A P +  + D  +T  +         R RG  R+
Sbjct: 689 AAG-PGPR----RGTCALGGSLGSLPASPFRIPEDDEYETTQECAPPPPPRPRARGASRR 743

Query: 472 KSGGSGERNSTPLKSAAAMESAQSSRLPWETWGSGGEGNSAGGAERPGPMGEAEKGAVLA 531
            S G      + L   AA  +  +      + GSGG     G A       +   GA+ A
Sbjct: 744 TSAGPRRWRRSRLNGLAAQRARAARDSLSLSSGSGG-----GSASASDDDADDADGALAA 798

Query: 532 QGQGDGTVSKGGRGPGSQHTKEAEDKIPLVPSKVSVIKGSRSQKEAFPLAKGEVDTAPQG 591
               + T   G RG       ++    P   S+      S S + +   ++G    A Q 
Sbjct: 799 ----ESTPFLGLRGAHDALRSDSPPLCPAADSRTYYSLDSHSTRASSRHSRGPPPRAKQD 854

Query: 592 NKDL 595
           +  L
Sbjct: 855 SAPL 858


>gi|4758832 neuregulin 2 isoform 1 [Homo sapiens]
          Length = 850

 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 61/244 (25%), Positives = 88/244 (36%), Gaps = 26/244 (10%)

Query: 364 TLPLSSRAGAPPAAVPIINMILPTVPAL-----PGPGPGPGRAPPGGLTQPRGTENREVG 418
           T P S+ A + P A PI   +    P L     PGPGPGPG  P  G    R  ++    
Sbjct: 621 TSPNSAHAVSLPPAAPISYRLAEQQPLLRHPAPPGPGPGPGPGPGPGADMQRSYDSYYYP 680

Query: 419 IGGDQGPHDKGVKRTAEVPVSEASGQAPPAKAAKQDIEDTASDA-------KRKRGRPRK 471
             G  GP     + T  +  S  S  A P +  + D  +T  +         R RG  R+
Sbjct: 681 AAG-PGPR----RGTCALGGSLGSLPASPFRIPEDDEYETTQECAPPPPPRPRARGASRR 735

Query: 472 KSGGSGERNSTPLKSAAAMESAQSSRLPWETWGSGGEGNSAGGAERPGPMGEAEKGAVLA 531
            S G      + L   AA  +  +      + GSGG     G A       +   GA+ A
Sbjct: 736 TSAGPRRWRRSRLNGLAAQRARAARDSLSLSSGSGG-----GSASASDDDADDADGALAA 790

Query: 532 QGQGDGTVSKGGRGPGSQHTKEAEDKIPLVPSKVSVIKGSRSQKEAFPLAKGEVDTAPQG 591
               + T   G RG       ++    P   S+      S S + +   ++G    A Q 
Sbjct: 791 ----ESTPFLGLRGAHDALRSDSPPLCPAADSRTYYSLDSHSTRASSRHSRGPPPRAKQD 846

Query: 592 NKDL 595
           +  L
Sbjct: 847 SAPL 850


>gi|239752764 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 370

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 74/292 (25%), Positives = 95/292 (32%), Gaps = 76/292 (26%)

Query: 275 GGAHKKPERLAQPP------------KDLEARTGAGPLARGERKKS---VVESSAPGAN- 318
           G    +  RLAQPP            +     TG  P  R  R  +   +  S APG   
Sbjct: 94  GAQQPRRRRLAQPPGSRAPLQVGGAPRRRAHLTGGPPRRRPPRLAAAHGLPASEAPGLRP 153

Query: 319 -----NLQVNALVARLPLLLPRAPRS--------LIPPIPVSPPILAPRLSSGALKVATL 365
                 L++    ARLP  LP AP +         + P+ + PP   P LS G  +   +
Sbjct: 154 DSARTRLRLRLASARLPRGLPPAPAAGLWRAGCTRLRPLLLQPP---PMLSPGLAQSPGV 210

Query: 366 PLSSRAGAPPAAVPIINMILPTVPALPGPGPGPGRAPPG------------------GLT 407
            L +R  + PA  P         P LP P P   R P                     LT
Sbjct: 211 ELHARTLSLPAPSP--------APCLPPPAPPAARTPSAHSPAHTHFTLTLAEAHTRALT 262

Query: 408 QPRGTENREVGIGGDQGPHDKGVKRTAEVPVSEASGQAPP------AKAAKQDIEDTASD 461
             RG      G  GD GP   G     +   S+ S  APP      A+A        A +
Sbjct: 263 PARG------GGEGDPGPIVGGRPENEDSLASQTSPPAPPAPVPSTARARSPGARRGARE 316

Query: 462 AKRKRGRPRKKSGGSGERNSTPLKSAAAMESAQSSRLPWETWGSGGEGNSAG 513
              + GR R+ SG       T  +  A  E           W  G     AG
Sbjct: 317 LAPRAGRRRQPSG------RTSWRRRARREQRDREPAVCGAWPRGSHAAGAG 362


>gi|146134388 YLP motif containing 1 [Homo sapiens]
          Length = 2146

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 51/201 (25%), Positives = 73/201 (36%), Gaps = 26/201 (12%)

Query: 330 PLLLPRAPRSLIPPIPVSPPILAPRLSSGALKVATLPLSSRAGAPPAAVPIINMILPTVP 389
           P ++P A  + +PP  + PP++ P L +        P  S AG PP   P         P
Sbjct: 544 PPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPP 603

Query: 390 ALPGPGPGPGRAPPGGLTQPRGTENREVGI---GGDQGPHDKGVKRTAEVPVSEASGQAP 446
            LP P       PP     P  +     GI   G  QG           +P    +   P
Sbjct: 604 VLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPGVPQG-----------IPPQLTAAPVP 652

Query: 447 PAKAAKQDIEDTASDAKRKRGRPRKKSGGSGERNS--TPLKSAAAMESAQS------SRL 498
           PA +++        +  R    P   S GS    +   PL+SA   E   S      S L
Sbjct: 653 PASSSQ---SSQVPEKPRPALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSAL 709

Query: 499 PWETWGSG-GEGNSAGGAERP 518
           P+ ++ S  G G S+    +P
Sbjct: 710 PYSSFSSDQGLGESSAAPSQP 730



 Score = 37.0 bits (84), Expect = 0.054
 Identities = 35/121 (28%), Positives = 53/121 (43%), Gaps = 22/121 (18%)

Query: 299  PLARGERKKSVVESSAPGANNLQVNALVARLPLLLPRAPRSLIPPIPVSPPILAPRLSSG 358
            P   G+   S+V  SAP A +   +  V R P+ +P  P    PP+P  PP++ P+ S+ 
Sbjct: 1515 PPPMGKPPGSIVRPSAPPARS---SVPVTRPPVPIPPPPPP--PPLPPPPPVIKPQTSAV 1569

Query: 359  ALK-------------VATLPLSSRAGAPPAAVPIINMILPTVP---ALPGPGPGPGRAP 402
              +                  L+S   +  AA+P    +LP  P   ++P PGP P   P
Sbjct: 1570 EQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSA-PVLPPPPVHSSIPPPGPVPMGMP 1628

Query: 403  P 403
            P
Sbjct: 1629 P 1629


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.130    0.381 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,808,742
Number of Sequences: 37866
Number of extensions: 1740403
Number of successful extensions: 12496
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 86
Number of HSP's successfully gapped in prelim test: 962
Number of HSP's that attempted gapping in prelim test: 9250
Number of HSP's gapped (non-prelim): 3475
length of query: 616
length of database: 18,247,518
effective HSP length: 108
effective length of query: 508
effective length of database: 14,157,990
effective search space: 7192258920
effective search space used: 7192258920
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.