Search of human proteins with 45359865

Search of human proteins with 45359865

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|45359865 matrix metalloproteinase 20 preproprotein [Homo
sapiens]
         (483 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|45359865 matrix metalloproteinase 20 preproprotein [Homo sapi...   998   0.0  
gi|4505217 matrix metalloproteinase 3 preproprotein [Homo sapiens]    425   e-119
gi|4505221 matrix metalloproteinase 8 preproprotein [Homo sapiens]    423   e-118
gi|4505205 matrix metalloproteinase 10 preproprotein [Homo sapiens]   417   e-117
gi|4505209 matrix metalloproteinase 13 preproprotein [Homo sapiens]   417   e-116
gi|4505215 matrix metalloproteinase 1 isoform 1 preproprotein [H...   407   e-113
gi|73858572 matrix metalloproteinase 12 preproprotein [Homo sapi...   403   e-112
gi|225543094 matrix metalloproteinase 1 isoform 2 [Homo sapiens]      384   e-106
gi|73808268 matrix metalloproteinase 27 [Homo sapiens]                371   e-103
gi|4826834 matrix metalloproteinase 14 preproprotein [Homo sapiens]   289   3e-78
gi|5729929 matrix metalloproteinase 24 preproprotein [Homo sapiens]   289   4e-78
gi|13027802 matrix metalloproteinase 16 isoform 1 preproprotein ...   275   5e-74
gi|4505211 matrix metalloproteinase 15 preproprotein [Homo sapiens]   258   6e-69
gi|4505219 matrix metalloproteinase 7 preproprotein [Homo sapiens]    257   2e-68
gi|11968059 matrix metalloproteinase 25 preproprotein [Homo sapi...   236   4e-62
gi|112382270 matrix metalloproteinase 17 preproprotein [Homo sap...   234   2e-61
gi|149999365 matrix metalloproteinase 16 isoform 2 preproprotein...   226   4e-59
gi|58331148 matrix metalloproteinase 11 preproprotein [Homo sapi...   224   2e-58
gi|4505213 matrix metalloproteinase 19 isoform rasi-1 preproprot...   193   3e-49
gi|11342666 matrix metalloproteinase 2 isoform a preproprotein [...   189   5e-48
gi|13236530 matrix metalloproteinase 28 isoform 1 preproprotein ...   188   1e-47
gi|189217853 matrix metalloproteinase 2 isoform b [Homo sapiens]      187   2e-47
gi|73808266 matrix metalloproteinase 26 preproprotein [Homo sapi...   183   3e-46
gi|74272287 matrix metalloproteinase 9 preproprotein [Homo sapiens]   152   7e-37
gi|22218341 matrix metalloproteinase 21 preproprotein [Homo sapi...   127   3e-29
gi|5902004 matrix metalloproteinase 23B precursor [Homo sapiens]       92   8e-19
gi|169203154 PREDICTED: similar to hCG2042634 [Homo sapiens]           81   2e-15
gi|169203660 PREDICTED: similar to hCG2042634 [Homo sapiens]           78   2e-14
gi|169202084 PREDICTED: similar to hCG2042634 [Homo sapiens]           78   2e-14
gi|239750339 PREDICTED: hypothetical protein XP_002347374 [Homo ...    65   1e-10

>gi|45359865 matrix metalloproteinase 20 preproprotein [Homo
           sapiens]
          Length = 483

 Score =  998 bits (2581), Expect = 0.0
 Identities = 483/483 (100%), Positives = 483/483 (100%)

Query: 1   MKVLPASGLAVFLIMALKFSTAAPSLVAASPRTWRNNYRLAQAYLDKYYTNKEGHQIGEM 60
           MKVLPASGLAVFLIMALKFSTAAPSLVAASPRTWRNNYRLAQAYLDKYYTNKEGHQIGEM
Sbjct: 1   MKVLPASGLAVFLIMALKFSTAAPSLVAASPRTWRNNYRLAQAYLDKYYTNKEGHQIGEM 60

Query: 61  VARGSNSMIRKIKELQAFFGLQVTGKLDQTTMNVIKKPRCGVPDVANYRLFPGEPKWKKN 120
           VARGSNSMIRKIKELQAFFGLQVTGKLDQTTMNVIKKPRCGVPDVANYRLFPGEPKWKKN
Sbjct: 61  VARGSNSMIRKIKELQAFFGLQVTGKLDQTTMNVIKKPRCGVPDVANYRLFPGEPKWKKN 120

Query: 121 TLTYRISKYTPSMSSVEVDKAVEMALQAWSSAVPLSFVRINSGEADIMISFENGDHGDSY 180
           TLTYRISKYTPSMSSVEVDKAVEMALQAWSSAVPLSFVRINSGEADIMISFENGDHGDSY
Sbjct: 121 TLTYRISKYTPSMSSVEVDKAVEMALQAWSSAVPLSFVRINSGEADIMISFENGDHGDSY 180

Query: 181 PFDGPRGTLAHAFAPGEGLGGDTHFDNAEKWTMGTNGFNLFTVAAHEFGHALGLAHSTDP 240
           PFDGPRGTLAHAFAPGEGLGGDTHFDNAEKWTMGTNGFNLFTVAAHEFGHALGLAHSTDP
Sbjct: 181 PFDGPRGTLAHAFAPGEGLGGDTHFDNAEKWTMGTNGFNLFTVAAHEFGHALGLAHSTDP 240

Query: 241 SALMYPTYKYKNPYGFHLPKDDVKGIQALYGPRKVFLGKPTLPHAPHHKPSIPDLCDSSS 300
           SALMYPTYKYKNPYGFHLPKDDVKGIQALYGPRKVFLGKPTLPHAPHHKPSIPDLCDSSS
Sbjct: 241 SALMYPTYKYKNPYGFHLPKDDVKGIQALYGPRKVFLGKPTLPHAPHHKPSIPDLCDSSS 300

Query: 301 SFDAVTMLGKELLLFKDRIFWRRQVHLRTGIRPSTITSSFPQLMSNVDAAYEVAERGTAY 360
           SFDAVTMLGKELLLFKDRIFWRRQVHLRTGIRPSTITSSFPQLMSNVDAAYEVAERGTAY
Sbjct: 301 SFDAVTMLGKELLLFKDRIFWRRQVHLRTGIRPSTITSSFPQLMSNVDAAYEVAERGTAY 360

Query: 361 FFKGPHYWITRGFQMQGPPRTIYDFGFPRHVQQIDAAVYLREPQKTLFFVGDEYYSYDER 420
           FFKGPHYWITRGFQMQGPPRTIYDFGFPRHVQQIDAAVYLREPQKTLFFVGDEYYSYDER
Sbjct: 361 FFKGPHYWITRGFQMQGPPRTIYDFGFPRHVQQIDAAVYLREPQKTLFFVGDEYYSYDER 420

Query: 421 KRKMEKDYPKNTEEEFSGVNGQIDAAVELNGYIYFFSGPKTYKYDTEKEDVVSVVKSSSW 480
           KRKMEKDYPKNTEEEFSGVNGQIDAAVELNGYIYFFSGPKTYKYDTEKEDVVSVVKSSSW
Sbjct: 421 KRKMEKDYPKNTEEEFSGVNGQIDAAVELNGYIYFFSGPKTYKYDTEKEDVVSVVKSSSW 480

Query: 481 IGC 483
           IGC
Sbjct: 481 IGC 483


>gi|4505217 matrix metalloproteinase 3 preproprotein [Homo sapiens]
          Length = 477

 Score =  425 bits (1093), Expect = e-119
 Identities = 222/479 (46%), Positives = 299/479 (62%), Gaps = 9/479 (1%)

Query: 9   LAVFLIMALKFSTAAPSLVAASPRTWRNNYRLAQAYLDKYYTNKEGHQIGEMVAR-GSNS 67
           L + L++ +   +A P   AA  R    +  L Q YL+ YY  K+   + + V R  S  
Sbjct: 4   LPILLLLCVAVCSAYPLDGAA--RGEDTSMNLVQKYLENYYDLKK--DVKQFVRRKDSGP 59

Query: 68  MIRKIKELQAFFGLQVTGKLDQTTMNVIKKPRCGVPDVANYRLFPGEPKWKKNTLTYRIS 127
           +++KI+E+Q F GL+VTGKLD  T+ V++KPRCGVPDV ++R FPG PKW+K  LTYRI 
Sbjct: 60  VVKKIREMQKFLGLEVTGKLDSDTLEVMRKPRCGVPDVGHFRTFPGIPKWRKTHLTYRIV 119

Query: 128 KYTPSMSSVEVDKAVEMALQAWSSAVPLSFVRINSGEADIMISFENGDHGDSYPFDGPRG 187
            YTP +    VD AVE AL+ W    PL+F R+  GEADIMISF   +HGD YPFDGP  
Sbjct: 120 NYTPDLPKDAVDSAVEKALKVWEEVTPLTFSRLYEGEADIMISFAVREHGDFYPFDGPGN 179

Query: 188 TLAHAFAPGEGLGGDTHFDNAEKWTMGTNGFNLFTVAAHEFGHALGLAHSTDPSALMYPT 247
            LAHA+APG G+ GD HFD+ E+WT  T G NLF VAAHE GH+LGL HS +  ALMYP 
Sbjct: 180 VLAHAYAPGPGINGDAHFDDDEQWTKDTTGTNLFLVAAHEIGHSLGLFHSANTEALMYPL 239

Query: 248 Y-KYKNPYGFHLPKDDVKGIQALYGPRKVFLGKPTLPHAP-HHKPSIPDLCDSSSSFDAV 305
           Y    +   F L +DD+ GIQ+LYGP       P +P  P   +P  P  CD + SFDAV
Sbjct: 240 YHSLTDLTRFRLSQDDINGIQSLYGPPPDSPETPLVPTEPVPPEPGTPANCDPALSFDAV 299

Query: 306 TMLGKELLLFKDRIFWRRQVHLRTGIRPSTITSSFPQLMSNVDAAYEVAERGTAYFFKGP 365
           + L  E+L+FKDR FWR+ +  +       I+S +P L S VDAAYEV  +   + FKG 
Sbjct: 300 STLRGEILIFKDRHFWRKSLR-KLEPELHLISSFWPSLPSGVDAAYEVTSKDLVFIFKGN 358

Query: 366 HYWITRGFQMQ-GPPRTIYDFGFPRHVQQIDAAVYLREPQKTLFFVGDEYYSYDERKRKM 424
            +W  RG +++ G PR I+  GFP  V++IDAA+  +E  KT FFV D+Y+ +DE++  M
Sbjct: 359 QFWAIRGNEVRAGYPRGIHTLGFPPTVRKIDAAISDKEKNKTYFFVEDKYWRFDEKRNSM 418

Query: 425 EKDYPKNTEEEFSGVNGQIDAAVELNGYIYFFSGPKTYKYDTEKEDVVSVVKSSSWIGC 483
           E  +PK   E+F G++ +IDA  E  G+ YFF+G    ++D   + V   +KS+SW+ C
Sbjct: 419 EPGFPKQIAEDFPGIDSKIDAVFEEFGFFYFFTGSSQLEFDPNAKKVTHTLKSNSWLNC 477


>gi|4505221 matrix metalloproteinase 8 preproprotein [Homo sapiens]
          Length = 467

 Score =  423 bits (1088), Expect = e-118
 Identities = 213/476 (44%), Positives = 296/476 (62%), Gaps = 19/476 (3%)

Query: 9   LAVFLIMALKFSTAAPSLVAASPRTWRNNYRLAQAYLDKYYTNKEGHQIGEMVARGSNSM 68
           L   L++ ++ S A P  V++  +    N +  Q YL+K+Y     +Q       G+N +
Sbjct: 7   LPFLLLLHVQISKAFP--VSSKEK----NTKTVQDYLEKFY-QLPSNQYQSTRKNGTNVI 59

Query: 69  IRKIKELQAFFGLQVTGKLDQTTMNVIKKPRCGVPDVANYRLFPGEPKWKKNTLTYRISK 128
           + K+KE+Q FFGL VTGK ++ T++++KKPRCGVPD   + L PG PKW++  LTYRI  
Sbjct: 60  VEKLKEMQRFFGLNVTGKPNEETLDMMKKPRCGVPDSGGFMLTPGNPKWERTNLTYRIRN 119

Query: 129 YTPSMSSVEVDKAVEMALQAWSSAVPLSFVRINSGEADIMISFENGDHGDSYPFDGPRGT 188
           YTP +S  EV++A++ A + WS A PL F RI+ GEADI I+F   DHGD+ PFDGP G 
Sbjct: 120 YTPQLSEAEVERAIKDAFELWSVASPLIFTRISQGEADINIAFYQRDHGDNSPFDGPNGI 179

Query: 189 LAHAFAPGEGLGGDTHFDNAEKWTMGTNGFNLFTVAAHEFGHALGLAHSTDPSALMYPTY 248
           LAHAF PG+G+GGD HFD  E WT  +  +NLF VAAHEFGH+LGLAHS+DP ALMYP Y
Sbjct: 180 LAHAFQPGQGIGGDAHFDAEETWTNTSANYNLFLVAAHEFGHSLGLAHSSDPGALMYPNY 239

Query: 249 KYKNPYGFHLPKDDVKGIQALYGPRKVFLGKPTLPHAPHHKPSIPDLCDSSSSFDAVTML 308
            ++    + LP+DD+ GIQA+YG        P  P      PS P  CD S +FDA+T L
Sbjct: 240 AFRETSNYSLPQDDIDGIQAIYG----LSSNPIQPTG----PSTPKPCDPSLTFDAITTL 291

Query: 309 GKELLLFKDRIFWRRQVHLRTGIRPSTITSSFPQLMSNVDAAYEVAERGTAYFFKGPHYW 368
             E+L FKDR FWRR   L+  +  + I+  +P L + + AAYE  +R   + FKG  YW
Sbjct: 292 RGEILFFKDRYFWRRHPQLQR-VEMNFISLFWPSLPTGIQAAYEDFDRDLIFLFKGNQYW 350

Query: 369 ITRGFQ-MQGPPRTIYDFGFPRHVQQIDAAVYLREPQKTLFFVGDEYYSYDERKRKMEKD 427
              G+  +QG P+ I ++GFP  VQ IDAAV+ R   KT FFV D+++ YD +++ ME  
Sbjct: 351 ALSGYDILQGYPKDISNYGFPSSVQAIDAAVFYR--SKTYFFVNDQFWRYDNQRQFMEPG 408

Query: 428 YPKNTEEEFSGVNGQIDAAVELNGYIYFFSGPKTYKYDTEKEDVVSVVKSSSWIGC 483
           YPK+    F G+  ++DA  +   + + FSGP+ Y +D   + V  V + + W+ C
Sbjct: 409 YPKSISGAFPGIESKVDAVFQQEHFFHVFSGPRYYAFDLIAQRVTRVARGNKWLNC 464


>gi|4505205 matrix metalloproteinase 10 preproprotein [Homo sapiens]
          Length = 476

 Score =  417 bits (1073), Expect = e-117
 Identities = 218/478 (45%), Positives = 297/478 (62%), Gaps = 8/478 (1%)

Query: 9   LAVFLIMALKFSTAAPSLVAASPRTWRNNYRLAQAYLDKYYTNKEGHQIGEMVARGSNSM 68
           LA  +++ L   +A P   AA      +N  LAQ YL+KYY  ++   + +   + SN +
Sbjct: 4   LAFLVLLCLPVCSAYPLSGAAKEED--SNKDLAQQYLEKYYNLEK--DVKQFRRKDSNLI 59

Query: 69  IRKIKELQAFFGLQVTGKLDQTTMNVIKKPRCGVPDVANYRLFPGEPKWKKNTLTYRISK 128
           ++KI+ +Q F GL+VTGKLD  T+ V++KPRCGVPDV ++  FPG PKW+K  LTYRI  
Sbjct: 60  VKKIQGMQKFLGLEVTGKLDTDTLEVMRKPRCGVPDVGHFSSFPGMPKWRKTHLTYRIVN 119

Query: 129 YTPSMSSVEVDKAVEMALQAWSSAVPLSFVRINSGEADIMISFENGDHGDSYPFDGPRGT 188
           YTP +    VD A+E AL+ W    PL+F R+  GEADIMISF   +HGD Y FDGP  +
Sbjct: 120 YTPDLPRDAVDSAIEKALKVWEEVTPLTFSRLYEGEADIMISFAVKEHGDFYSFDGPGHS 179

Query: 189 LAHAFAPGEGLGGDTHFDNAEKWTMGTNGFNLFTVAAHEFGHALGLAHSTDPSALMYPTY 248
           LAHA+ PG GL GD HFD+ EKWT   +G NLF VAAHE GH+LGL HS +  ALMYP Y
Sbjct: 180 LAHAYPPGPGLYGDIHFDDDEKWTEDASGTNLFLVAAHELGHSLGLFHSANTEALMYPLY 239

Query: 249 -KYKNPYGFHLPKDDVKGIQALYGPRKVFLGKPTLPHAPHHKPS-IPDLCDSSSSFDAVT 306
             +     F L +DDV GIQ+LYGP      +P +P       S +P  CD + SFDA++
Sbjct: 240 NSFTELAQFRLSQDDVNGIQSLYGPPPASTEEPLVPTKSVPSGSEMPAKCDPALSFDAIS 299

Query: 307 MLGKELLLFKDRIFWRRQVHLRTGIRPSTITSSFPQLMSNVDAAYEVAERGTAYFFKGPH 366
            L  E L FKDR FWRR  H         I++ +P L S +DAAYEV  R T + FKG  
Sbjct: 300 TLRGEYLFFKDRYFWRRS-HWNPEPEFHLISAFWPSLPSYLDAAYEVNSRDTVFIFKGNE 358

Query: 367 YWITRGFQMQ-GPPRTIYDFGFPRHVQQIDAAVYLREPQKTLFFVGDEYYSYDERKRKME 425
           +W  RG ++Q G PR I+  GFP  +++IDAAV  +E +KT FF  D+Y+ +DE  + ME
Sbjct: 359 FWAIRGNEVQAGYPRGIHTLGFPPTIRKIDAAVSDKEKKKTYFFAADKYWRFDENSQSME 418

Query: 426 KDYPKNTEEEFSGVNGQIDAAVELNGYIYFFSGPKTYKYDTEKEDVVSVVKSSSWIGC 483
           + +P+   ++F GV  ++DA ++  G+ YFFSG   +++D     V  ++KS+SW+ C
Sbjct: 419 QGFPRLIADDFPGVEPKVDAVLQAFGFFYFFSGSSQFEFDPNARMVTHILKSNSWLHC 476


>gi|4505209 matrix metalloproteinase 13 preproprotein [Homo sapiens]
          Length = 471

 Score =  417 bits (1071), Expect = e-116
 Identities = 209/447 (46%), Positives = 281/447 (62%), Gaps = 14/447 (3%)

Query: 39  RLAQAYLDKYYTNKEGHQIGEMVARGSNSMIRKIKELQAFFGLQVTGKLDQTTMNVIKKP 98
           + A+ YL  YY     +  G +    ++SM  +++E+Q+FFGL+VTGKLD  T++V+KKP
Sbjct: 37  QFAERYLRSYY--HPTNLAGILKENAASSMTERLREMQSFFGLEVTGKLDDNTLDVMKKP 94

Query: 99  RCGVPDVANYRLFPGEPKWKKNTLTYRISKYTPSMSSVEVDKAVEMALQAWSSAVPLSFV 158
           RCGVPDV  Y +FP   KW K  LTYRI  YTP M+  EV+KA + A + WS   PL+F 
Sbjct: 95  RCGVPDVGEYNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFT 154

Query: 159 RINSGEADIMISFENGDHGDSYPFDGPRGTLAHAFAPGEGLGGDTHFDNAEKWTMGTNGF 218
           R++ G ADIMISF   +HGD YPFDGP G LAHAF PG   GGD HFD+ E WT  + G+
Sbjct: 155 RLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGY 214

Query: 219 NLFTVAAHEFGHALGLAHSTDPSALMYPTYKYKNPYGFHLPKDDVKGIQALYGPRKVFLG 278
           NLF VAAHEFGH+LGL HS DP ALM+P Y Y     F LP DDV+GIQ+LYGP      
Sbjct: 215 NLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGP------ 268

Query: 279 KPTLPHAPHHKPSIPDLCDSSSSFDAVTMLGKELLLFKDRIFWRRQVHLRTGIRPSTITS 338
               P+  H  P  PD CD S S DA+T L  E ++FKDR FWR  +H +       +T 
Sbjct: 269 GDEDPNPKH--PKTPDKCDPSLSLDAITSLRGETMIFKDRFFWR--LHPQQVDAELFLTK 324

Query: 339 SF-PQLMSNVDAAYEVAERGTAYFFKGPHYWITRGFQ-MQGPPRTIYDFGFPRHVQQIDA 396
           SF P+L + +DAAYE       + F+G  +W   G+  ++G P+ I + G P+ V++I A
Sbjct: 325 SFWPELPNRIDAAYEHPSHDLIFIFRGRKFWALNGYDILEGYPKKISELGLPKEVKKISA 384

Query: 397 AVYLREPQKTLFFVGDEYYSYDERKRKMEKDYPKNTEEEFSGVNGQIDAAVELNGYIYFF 456
           AV+  +  KTL F G++ + YD+    M+KDYP+  EE+F G+  ++DA  E NGYIYFF
Sbjct: 385 AVHFEDTGKTLLFSGNQVWRYDDTNHIMDKDYPRLIEEDFPGIGDKVDAVYEKNGYIYFF 444

Query: 457 SGPKTYKYDTEKEDVVSVVKSSSWIGC 483
           +GP  ++Y      +V V+ ++S + C
Sbjct: 445 NGPIQFEYSIWSNRIVRVMPANSILWC 471


>gi|4505215 matrix metalloproteinase 1 isoform 1 preproprotein [Homo
           sapiens]
          Length = 469

 Score =  407 bits (1045), Expect = e-113
 Identities = 207/458 (45%), Positives = 286/458 (62%), Gaps = 16/458 (3%)

Query: 29  ASPRTWRNNYRLAQAYLDKYYTNK-EGHQIGEMVARGSNSMIRKIKELQAFFGLQVTGKL 87
           A+  T   +  L Q YL+KYY  K +G Q+ +   R S  ++ K+K++Q FFGL+VTGK 
Sbjct: 22  ATLETQEQDVDLVQKYLEKYYNLKNDGRQVEKR--RNSGPVVEKLKQMQEFFGLKVTGKP 79

Query: 88  DQTTMNVIKKPRCGVPDVANYRLFPGEPKWKKNTLTYRISKYTPSMSSVEVDKAVEMALQ 147
           D  T+ V+K+PRCGVPDVA + L  G P+W++  LTYRI  YTP +   +VD A+E A Q
Sbjct: 80  DAETLKVMKQPRCGVPDVAQFVLTEGNPRWEQTHLTYRIENYTPDLPRADVDHAIEKAFQ 139

Query: 148 AWSSAVPLSFVRINSGEADIMISFENGDHGDSYPFDGPRGTLAHAFAPGEGLGGDTHFDN 207
            WS+  PL+F +++ G+ADIMISF  GDH D+ PFDGP G LAHAF PG G+GGD HFD 
Sbjct: 140 LWSNVTPLTFTKVSEGQADIMISFVRGDHRDNSPFDGPGGNLAHAFQPGPGIGGDAHFDE 199

Query: 208 AEKWTMGTNGFNLFTVAAHEFGHALGLAHSTDPSALMYPTYKYKNPYGFHLPKDDVKGIQ 267
            E+WT     +NL  VAAHE GH+LGL+HSTD  ALMYP+Y +       L +DD+ GIQ
Sbjct: 200 DERWTNNFREYNLHRVAAHELGHSLGLSHSTDIGALMYPSYTFSG--DVQLAQDDIDGIQ 257

Query: 268 ALYGPRKVFLGKPTLPHAPHHKPSIPDLCDSSSSFDAVTMLGKELLLFKDRIFWRRQVHL 327
           A+YG  +     P  P      P  P  CDS  +FDA+T +  E++ FKDR F+ R    
Sbjct: 258 AIYGRSQ----NPVQPIG----PQTPKACDSKLTFDAITTIRGEVMFFKDR-FYMRTNPF 308

Query: 328 RTGIRPSTITSSFPQLMSNVDAAYEVAERGTAYFFKGPHYWITRGFQ-MQGPPRTIY-DF 385
              +  + I+  +PQL + ++AAYE A+R    FFKG  YW  +G   + G P+ IY  F
Sbjct: 309 YPEVELNFISVFWPQLPNGLEAAYEFADRDEVRFFKGNKYWAVQGQNVLHGYPKDIYSSF 368

Query: 386 GFPRHVQQIDAAVYLREPQKTLFFVGDEYYSYDERKRKMEKDYPKNTEEEFSGVNGQIDA 445
           GFPR V+ IDAA+      KT FFV ++Y+ YDE KR M+  YPK    +F G+  ++DA
Sbjct: 369 GFPRTVKHIDAALSEENTGKTYFFVANKYWRYDEYKRSMDPGYPKMIAHDFPGIGHKVDA 428

Query: 446 AVELNGYIYFFSGPKTYKYDTEKEDVVSVVKSSSWIGC 483
               +G+ YFF G + YK+D + + ++++ K++SW  C
Sbjct: 429 VFMKDGFFYFFHGTRQYKFDPKTKRILTLQKANSWFNC 466


>gi|73858572 matrix metalloproteinase 12 preproprotein [Homo
           sapiens]
          Length = 470

 Score =  403 bits (1035), Expect = e-112
 Identities = 207/479 (43%), Positives = 293/479 (61%), Gaps = 18/479 (3%)

Query: 12  FLIMALKFSTAAPSL-VAASPRTWRNNYRLAQAYLDKYYTNKEGHQIGEMVARGSNSMIR 70
           FL++ L  +TA+ +L + +S    +NN    + YL+K+Y  +        +    N M  
Sbjct: 3   FLLILLLQATASGALPLNSSTSLEKNNVLFGERYLEKFYGLEINKLPVTKMKYSGNLMKE 62

Query: 71  KIKELQAFFGLQVTGKLDQTTMNVIKKPRCGVPDVANYRLFPGEPKWKKNTLTYRISKYT 130
           KI+E+Q F GL+VTG+LD +T+ ++  PRCGVPDV ++R  PG P W+K+ +TYRI+ YT
Sbjct: 63  KIQEMQHFLGLKVTGQLDTSTLEMMHAPRCGVPDVHHFREMPGGPVWRKHYITYRINNYT 122

Query: 131 PSMSSVEVDKAVEMALQAWSSAVPLSFVRINSGEADIMISFENGDHGDSYPFDGPRGTLA 190
           P M+  +VD A+  A Q WS+  PL F +IN+G ADI++ F  G HGD + FDG  G LA
Sbjct: 123 PDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDFHAFDGKGGILA 182

Query: 191 HAFAPGEGLGGDTHFDNAEKWTMGTNGFNLFTVAAHEFGHALGLAHSTDPSALMYPTYKY 250
           HAF PG G+GGD HFD  E WT  + G NLF  A HE GH+LGL HS+DP A+M+PTYKY
Sbjct: 183 HAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKY 242

Query: 251 KNPYGFHLPKDDVKGIQALYGPRKVFLGKPTLPHAPHHKPSIPDLCDSSSSFDAVTMLGK 310
            +   F L  DD++GIQ+LYG  K       LP+  + +P+   LCD + SFDAVT +G 
Sbjct: 243 VDINTFRLSADDIRGIQSLYGDPK---ENQRLPNPDNSEPA---LCDPNLSFDAVTTVGN 296

Query: 311 ELLLFKDRIFWRRQVHLRTGIRPST----ITSSFPQLMSNVDAAYEVAERGTAYFFKGPH 366
           ++  FKDR FW     L+   RP T    I+S +P L S ++AAYE+  R   + FK   
Sbjct: 297 KIFFFKDRFFW-----LKVSERPKTSVNLISSLWPTLPSGIEAAYEIEARNQVFLFKDDK 351

Query: 367 YWITRGFQMQ-GPPRTIYDFGFPRHVQQIDAAVYLREPQKTLFFVGDEYYSYDERKRKME 425
           YW+    + +   P++I+ FGFP  V++IDAAV+     +T FFV ++Y+ YDER++ M+
Sbjct: 352 YWLISNLRPEPNYPKSIHSFGFPNFVKKIDAAVFNPRFYRTYFFVDNQYWRYDERRQMMD 411

Query: 426 KDYPKNTEEEFSGVNGQIDAA-VELNGYIYFFSGPKTYKYDTEKEDVVSVVKSSSWIGC 483
             YPK   + F G+  +IDA     N Y YFF G   ++YD   + +   +KS+SW GC
Sbjct: 412 PGYPKLITKNFQGIGPKIDAVFYSKNKYYYFFQGSNQFEYDFLLQRITKTLKSNSWFGC 470


>gi|225543094 matrix metalloproteinase 1 isoform 2 [Homo sapiens]
          Length = 403

 Score =  384 bits (985), Expect = e-106
 Identities = 191/411 (46%), Positives = 260/411 (63%), Gaps = 13/411 (3%)

Query: 75  LQAFFGLQVTGKLDQTTMNVIKKPRCGVPDVANYRLFPGEPKWKKNTLTYRISKYTPSMS 134
           +Q FFGL+VTGK D  T+ V+K+PRCGVPDVA + L  G P+W++  LTYRI  YTP + 
Sbjct: 1   MQEFFGLKVTGKPDAETLKVMKQPRCGVPDVAQFVLTEGNPRWEQTHLTYRIENYTPDLP 60

Query: 135 SVEVDKAVEMALQAWSSAVPLSFVRINSGEADIMISFENGDHGDSYPFDGPRGTLAHAFA 194
             +VD A+E A Q WS+  PL+F +++ G+ADIMISF  GDH D+ PFDGP G LAHAF 
Sbjct: 61  RADVDHAIEKAFQLWSNVTPLTFTKVSEGQADIMISFVRGDHRDNSPFDGPGGNLAHAFQ 120

Query: 195 PGEGLGGDTHFDNAEKWTMGTNGFNLFTVAAHEFGHALGLAHSTDPSALMYPTYKYKNPY 254
           PG G+GGD HFD  E+WT     +NL  VAAHE GH+LGL+HSTD  ALMYP+Y +    
Sbjct: 121 PGPGIGGDAHFDEDERWTNNFREYNLHRVAAHELGHSLGLSHSTDIGALMYPSYTFSG-- 178

Query: 255 GFHLPKDDVKGIQALYGPRKVFLGKPTLPHAPHHKPSIPDLCDSSSSFDAVTMLGKELLL 314
              L +DD+ GIQA+YG  +     P  P      P  P  CDS  +FDA+T +  E++ 
Sbjct: 179 DVQLAQDDIDGIQAIYGRSQ----NPVQPIG----PQTPKACDSKLTFDAITTIRGEVMF 230

Query: 315 FKDRIFWRRQVHLRTGIRPSTITSSFPQLMSNVDAAYEVAERGTAYFFKGPHYWITRGFQ 374
           FKDR F+ R       +  + I+  +PQL + ++AAYE A+R    FFKG  YW  +G  
Sbjct: 231 FKDR-FYMRTNPFYPEVELNFISVFWPQLPNGLEAAYEFADRDEVRFFKGNKYWAVQGQN 289

Query: 375 -MQGPPRTIY-DFGFPRHVQQIDAAVYLREPQKTLFFVGDEYYSYDERKRKMEKDYPKNT 432
            + G P+ IY  FGFPR V+ IDAA+      KT FFV ++Y+ YDE KR M+  YPK  
Sbjct: 290 VLHGYPKDIYSSFGFPRTVKHIDAALSEENTGKTYFFVANKYWRYDEYKRSMDPGYPKMI 349

Query: 433 EEEFSGVNGQIDAAVELNGYIYFFSGPKTYKYDTEKEDVVSVVKSSSWIGC 483
             +F G+  ++DA    +G+ YFF G + YK+D + + ++++ K++SW  C
Sbjct: 350 AHDFPGIGHKVDAVFMKDGFFYFFHGTRQYKFDPKTKRILTLQKANSWFNC 400


>gi|73808268 matrix metalloproteinase 27 [Homo sapiens]
          Length = 513

 Score =  371 bits (953), Expect = e-103
 Identities = 200/478 (41%), Positives = 292/478 (61%), Gaps = 19/478 (3%)

Query: 9   LAVFLIMALKFSTAAPSLVAASPRTWRNNYRLAQAYLDKYYTNK-EGHQIGEMVARGSNS 67
           L +  +  + FS+A P LV  +      N +LAQAYL+++Y+ + EG+ + +  ++  + 
Sbjct: 4   LLLLFLFFITFSSAFP-LVRMTEN--EENMQLAQAYLNQFYSLEIEGNHLVQ--SKNRSL 58

Query: 68  MIRKIKELQAFFGLQVTGKLDQTTMNVIKKPRCGVPDVANYRLFPGEPKWKKNTLTYRIS 127
           +  KI+E+QAFFGL VTGKLD  T+ ++K PRCGVPDV  Y      P W+K  LTYRI 
Sbjct: 59  IDDKIREMQAFFGLTVTGKLDSNTLEIMKTPRCGVPDVGQYGYTL--PGWRKYNLTYRII 116

Query: 128 KYTPSMSSVEVDKAVEMALQAWSSAVPLSFVRINSGEADIMISFENGDHGDSYP-FDGPR 186
            YTP M+   VD+A++  L+ WS   PL F +I+ G ADIMI+F    HG     FDGP 
Sbjct: 117 NYTPDMARAAVDEAIQEGLEVWSKVTPLKFTKISKGIADIMIAFRTRVHGRCPRYFDGPL 176

Query: 187 GTLAHAFAPGEGLGGDTHFDNAEKWTMGTNGFNLFTVAAHEFGHALGLAHSTDPSALMYP 246
           G L HAF PG GLGGDTHFD  E WT    GFNLF VAAHEFGHALGL+HS D +ALM+P
Sbjct: 177 GVLGHAFPPGPGLGGDTHFDEDENWTKDGAGFNLFLVAAHEFGHALGLSHSNDQTALMFP 236

Query: 247 TYKYKNPYGFHLPKDDVKGIQALYGPRKVFLGKPTLPHAPHHKPSIPDLCDSSSSFDAVT 306
            Y   +P  + L +DD+ GIQ++YG      G P  P  P  +P+IP  CD   +FDA+T
Sbjct: 237 NYVSLDPRKYPLSQDDINGIQSIYG------GLPKEPAKP-KEPTIPHACDPDLTFDAIT 289

Query: 307 MLGKELLLFKDRIFWRRQVHLRTGIRPSTITSSFPQLMSNVDAAYEVAERGTAYFFKGPH 366
              +E++ FK R  WR    + T +    I S +P L +++ AAYE   R     FK  +
Sbjct: 290 TFRREVMFFKGRHLWRIYYDI-TDVEFELIASFWPSLPADLQAAYE-NPRDKILVFKDEN 347

Query: 367 YWITRGFQ-MQGPPRTIYDFGFPRHVQQIDAAVYLREPQKTLFFVGDEYYSYDERKRKME 425
           +W+ RG+  +   P++I+  GFP  V++IDAAV  +  +KT FFVG   + +DE  + M+
Sbjct: 348 FWMIRGYAVLPDYPKSIHTLGFPGRVKKIDAAVCDKTTRKTYFFVGIWCWRFDEMTQTMD 407

Query: 426 KDYPKNTEEEFSGVNGQIDAAVELNGYIYFFSGPKTYKYDTEKEDVVSVVKSSSWIGC 483
           K +P+   + F G++ ++DAA +  G+ +F  G K ++YD + +++  ++++++W  C
Sbjct: 408 KGFPQRVVKHFPGISIRVDAAFQYKGFFFFSRGSKQFEYDIKTKNITRIMRTNTWFQC 465


>gi|4826834 matrix metalloproteinase 14 preproprotein [Homo sapiens]
          Length = 582

 Score =  289 bits (740), Expect = 3e-78
 Identities = 183/509 (35%), Positives = 267/509 (52%), Gaps = 50/509 (9%)

Query: 13  LIMALKFSTAAPSLVAASPRTWRNNYRLAQAYLDKYYTNKEGHQIGEMVARGSNSMIRKI 72
           L+  L   TA  SL +A   ++       +A+L +Y     G  +     R   S+   I
Sbjct: 12  LLPLLTLGTALASLGSAQSSSFS-----PEAWLQQYGYLPPG-DLRTHTQRSPQSLSAAI 65

Query: 73  KELQAFFGLQVTGKLDQTTMNVIKKPRCGVPD---------VANYRLFPGEPKWKKNTLT 123
             +Q F+GLQVTGK D  TM  +++PRCGVPD         V   R      KW+ N +T
Sbjct: 66  AAMQKFYGLQVTGKADADTMKAMRRPRCGVPDKFGAEIKANVRRKRYAIQGLKWQHNEIT 125

Query: 124 YRISKYTPSMSSVEVDKAVEMALQAWSSAVPLSFVRI--------NSGEADIMISFENGD 175
           + I  YTP +      +A+  A + W SA PL F  +        +  +ADIMI F  G 
Sbjct: 126 FCIQNYTPKVGEYATYEAIRKAFRVWESATPLRFREVPYAYIREGHEKQADIMIFFAEGF 185

Query: 176 HGDSYPFDGPRGTLAHAFAPGEGLGGDTHFDNAEKWTMGT---NGFNLFTVAAHEFGHAL 232
           HGDS PFDG  G LAHA+ PG  +GGDTHFD+AE WT+     NG ++F VA HE GHAL
Sbjct: 186 HGDSTPFDGEGGFLAHAYFPGPNIGGDTHFDSAEPWTVRNEDLNGNDIFLVAVHELGHAL 245

Query: 233 GLAHSTDPSALMYPTYKYKNPYGFHLPKDDVKGIQALYG----------PRKVFLGKPTL 282
           GL HS+DPSA+M P Y++ +   F LP DD +GIQ LYG          P+     +P++
Sbjct: 246 GLEHSSDPSAIMAPFYQWMDTENFVLPDDDRRGIQQLYGGESGFPTKMPPQPRTTSRPSV 305

Query: 283 PHAPHHKPSIPDLCDSSSSFDAVTMLGKELLLFKDRIFWRRQVHLRTGIRPSTITSSFPQ 342
           P  P +    P++CD   +FD V ML  E+ +FK+R FWR + +      P  I   +  
Sbjct: 306 PDKPKNPTYGPNICD--GNFDTVAMLRGEMFVFKERWFWRVRNNQVMDGYPMPIGQFWRG 363

Query: 343 LMSNVDAAYEVAERGTAYFFKGPHYWITRGFQMQ-GPPRTIYDFGFPRHVQQIDAAVYLR 401
           L ++++ AYE  + G   FFKG  +W+     ++ G P+ I + G      +IDAA++  
Sbjct: 364 LPASINTAYE-RKDGKFVFFKGDKHWVFDEASLEPGYPKHIKELGRGLPTDKIDAALFWM 422

Query: 402 EPQKTLFFVGDEYYSYDERKRKMEKDYPKNTEEEFSGV----NGQIDAAVELNGYIYFFS 457
              KT FF G++YY ++E  R ++ +YPKN  + + G+     G    + E+  + YF+ 
Sbjct: 423 PNGKTYFFRGNKYYRFNEELRAVDSEYPKNI-KVWEGIPESPRGSFMGSDEV--FTYFYK 479

Query: 458 GPKTYKYDTEKEDVVSVVKSSS---WIGC 483
           G K +K++ +K  V      S+   W+GC
Sbjct: 480 GNKYWKFNNQKLKVEPGYPKSALRDWMGC 508


>gi|5729929 matrix metalloproteinase 24 preproprotein [Homo sapiens]
          Length = 645

 Score =  289 bits (739), Expect = 4e-78
 Identities = 176/463 (38%), Positives = 241/463 (52%), Gaps = 55/463 (11%)

Query: 72  IKELQAFFGLQVTGKLDQTTMNVIKKPRCGVPDVA-------NYRLFPGEPKWKKNTLTY 124
           +  +Q F+G+ VTG LDQTT+  +KKPRCGVPD         N R      KW++  +TY
Sbjct: 111 VSTMQQFYGIPVTGVLDQTTIEWMKKPRCGVPDHPHLSRRRRNKRYALTGQKWRQKHITY 170

Query: 125 RISKYTPSMSSVEVDKAVEMALQAWSSAVPLSF-------VRINSGEADIMISFENGDHG 177
            I  YTP +  ++  KA+  A   W    PL+F       ++ +  EADIMI F +G HG
Sbjct: 171 SIHNYTPKVGELDTRKAIRQAFDVWQKVTPLTFEEVPYHEIKSDRKEADIMIFFASGFHG 230

Query: 178 DSYPFDGPRGTLAHAFAPGEGLGGDTHFDNAEKWTMGT---NGFNLFTVAAHEFGHALGL 234
           DS PFDG  G LAHA+ PG G+GGDTHFD+ E WT+G    +G +LF VA HE GHALGL
Sbjct: 231 DSSPFDGEGGFLAHAYFPGPGIGGDTHFDSDEPWTLGNANHDGNDLFLVAVHELGHALGL 290

Query: 235 AHSTDPSALMYPTYKYKNPYGFHLPKDDVKGIQALYGPRKVFLGK----PTLPHAPHHKP 290
            HS+DPSA+M P Y+Y   + F LP+DD++GIQ +YGP    L      PTLP    H P
Sbjct: 291 EHSSDPSAIMAPFYQYMETHNFKLPQDDLQGIQKIYGPPAEPLEPTRPLPTLPVRRIHSP 350

Query: 291 S------------------------IPDLCDSSSSFDAVTMLGKELLLFKDRIFWR-RQV 325
           S                         P++CD   +F+ V +   E+ +FKDR FWR R  
Sbjct: 351 SERKHERQPRPPRPPLGDRPSTPGTKPNICD--GNFNTVALFRGEMFVFKDRWFWRLRNN 408

Query: 326 HLRTGIRPSTITSSFPQLMSNVDAAYEVAERGTAYFFKGPHYWITRGFQMQ-GPPRTIYD 384
            ++ G  P  I   +  L + +DAAYE A+ G   FFKG  YW+ +   ++ G P ++ +
Sbjct: 409 RVQEGY-PMQIEQFWKGLPARIDAAYERAD-GRFVFFKGDKYWVFKEVTVEPGYPHSLGE 466

Query: 385 FGFPRHVQQIDAAVYLREPQKTLFFVGDEYYSYDERKRKMEKDYPKNTEEEFSGVNGQID 444
            G     + ID A+      KT FF G+ Y+ Y E +R  +  YPK              
Sbjct: 467 LGSCLPREGIDTALRWEPVGKTYFFKGERYWRYSEERRATDPGYPKPITVWKGIPQAPQG 526

Query: 445 AAVELNG-YIYFFSGPKTYKYDTEKEDVVSVVKSS---SWIGC 483
           A +   G Y YF+ G   +K+D +K  V      +    W+GC
Sbjct: 527 AFISKEGYYTYFYKGRDYWKFDNQKLSVEPGYPRNILRDWMGC 569


>gi|13027802 matrix metalloproteinase 16 isoform 1 preproprotein
           [Homo sapiens]
          Length = 607

 Score =  275 bits (704), Expect = 5e-74
 Identities = 165/458 (36%), Positives = 237/458 (51%), Gaps = 57/458 (12%)

Query: 61  VARGSNSMIRKIKELQAFFGLQVTGKLDQTTMNVIKKPRCGVPD---------VANYRLF 111
           V R + +M   +  +Q F+G+ +TGK+D+ T++ +KKPRCGVPD         +   R  
Sbjct: 62  VLRSAETMQSALAAMQQFYGINMTGKVDRNTIDWMKKPRCGVPDQTRGSSKFHIRRKRYA 121

Query: 112 PGEPKWKKNTLTYRISKYTPSMSSVEVDKAVEMALQAWSSAVPLSFVRINSGE------- 164
               KW+   +TY I   TP +   E  KA+  A   W +  PL+F  +   E       
Sbjct: 122 LTGQKWQHKHITYSIKNVTPKVGDPETRKAIRRAFDVWQNVTPLTFEEVPYSELENGKRD 181

Query: 165 ADIMISFENGDHGDSYPFDGPRGTLAHAFAPGEGLGGDTHFDNAEKWTMGT---NGFNLF 221
            DI I F +G HGDS PFDG  G LAHA+ PG G+GGDTHFD+ E WT+G    +G +LF
Sbjct: 182 VDITIIFASGFHGDSSPFDGEGGFLAHAYFPGPGIGGDTHFDSDEPWTLGNPNHDGNDLF 241

Query: 222 TVAAHEFGHALGLAHSTDPSALMYPTYKYKNPYGFHLPKDDVKGIQALYG---------- 271
            VA HE GHALGL HS DP+A+M P Y+Y     F LP DD++GIQ +YG          
Sbjct: 242 LVAVHELGHALGLEHSNDPTAIMAPFYQYMETDNFKLPNDDLQGIQKIYGPPDKIPPPTR 301

Query: 272 ---------------PRKVFLGKPTLPHAPHHKPSI----PDLCDSSSSFDAVTMLGKEL 312
                          PRK    KP  P  P  +PS     P++CD   +F+ + +L +E+
Sbjct: 302 PLPTVPPHRSIPPADPRKNDRPKP--PRPPTGRPSYPGAKPNICD--GNFNTLAILRREM 357

Query: 313 LLFKDRIFWRRQVHLRTGIRPSTITSSFPQLMSNVDAAYEVAERGTAYFFKGPHYWITRG 372
            +FKD+ FWR + +      P  IT  +  L  ++DA YE ++ G   FFKG  YW+ + 
Sbjct: 358 FVFKDQWFWRVRNNRVMDGYPMQITYFWRGLPPSIDAVYENSD-GNFVFFKGNKYWVFKD 416

Query: 373 FQMQ-GPPRTIYDFGFPRHVQQIDAAVYLREPQKTLFFVGDEYYSYDERKRKMEKDYPKN 431
             +Q G P  +   G       ID+A++  +  KT FF GD Y+ Y E  + M+  YPK 
Sbjct: 417 TTLQPGYPHDLITLGSGIPPHGIDSAIWWEDVGKTYFFKGDRYWRYSEEMKTMDPGYPKP 476

Query: 432 TEEEFSGVNGQIDAAV--ELNGYIYFFSGPKTYKYDTE 467
               + G+      A   + NG+ YF+ G + +K++ +
Sbjct: 477 I-TVWKGIPESPQGAFVHKENGFTYFYKGKEYWKFNNQ 513


>gi|4505211 matrix metalloproteinase 15 preproprotein [Homo sapiens]
          Length = 669

 Score =  258 bits (660), Expect = 6e-69
 Identities = 163/472 (34%), Positives = 228/472 (48%), Gaps = 70/472 (14%)

Query: 63  RGSNSMIRKIKELQAFFGLQVTGKLDQTTMNVIKKPRCGVPDVANYRLFPG--------- 113
           R +  +   + E+Q F+G+ VTG LD+ T   +K+PRCGVPD    R+            
Sbjct: 74  RSAQILASALAEMQRFYGIPVTGVLDEETKEWMKRPRCGVPDQFGVRVKANLRRRRKRYA 133

Query: 114 --EPKWKKNTLTYRISKYTPSMSSVEVDKAVEMALQAWSSAVPLSFVRI--------NSG 163
               KW  + LT+ I  YT  +      +AV  A + W  A PL F  +           
Sbjct: 134 LTGRKWNNHHLTFSIQNYTEKLGWYHSMEAVRRAFRVWEQATPLVFQEVPYEDIRLRRQK 193

Query: 164 EADIMISFENGDHGDSYPFDGPRGTLAHAFAPGEGLGGDTHFDNAEKWTMGT---NGFNL 220
           EADIM+ F +G HGDS PFDG  G LAHA+ PG GLGGDTHFD  E WT  +   +G NL
Sbjct: 194 EADIMVLFASGFHGDSSPFDGTGGFLAHAYFPGPGLGGDTHFDADEPWTFSSTDLHGNNL 253

Query: 221 FTVAAHEFGHALGLAHSTDPSALMYPTYKYKNPYGFHLPKDDVKGIQALYG--------P 272
           F VA HE GHALGL HS++P+A+M P Y++K+   F LP+DD++GIQ LYG         
Sbjct: 254 FLVAVHELGHALGLEHSSNPNAIMAPFYQWKDVDNFKLPEDDLRGIQQLYGTPDGQPQPT 313

Query: 273 RKVFLGKPTLPHAPHHKPSI---------------------------------PDLCDSS 299
           + +    P  P  P H+P                                   P++CD  
Sbjct: 314 QPLPTVTPRRPGRPDHRPPRPPQPPPPGGKPERPPKPGPPVQPRATERPDQYGPNICD-- 371

Query: 300 SSFDAVTMLGKELLLFKDRIFWRRQVHLRTGIRPSTITSSFPQLMSNVDAAYEVAERGTA 359
             FD V ML  E+ +FK R FWR + +      P  I   +  L  ++ AAYE  + G  
Sbjct: 372 GDFDTVAMLRGEMFVFKGRWFWRVRHNRVLDNYPMPIGHFWRGLPGDISAAYE-RQDGRF 430

Query: 360 YFFKGPHYWITRGFQMQ-GPPRTIYDFGFPRHVQQIDAAVYLREPQKTLFFVGDEYYSYD 418
            FFKG  YW+ R   ++ G P+ +  +G      +ID A++      T FF  D Y+ ++
Sbjct: 431 VFFKGDRYWLFREANLEPGYPQPLTSYGLGIPYDRIDTAIWWEPTGHTFFFQEDRYWRFN 490

Query: 419 ERKRKMEKDYPKNTEEEFSGVNGQIDAAVELN--GYIYFFSGPKTYKYDTEK 468
           E  ++ +  YPK     + G+      A   N   Y YF+ G K +K+D E+
Sbjct: 491 EETQRGDPGYPKPI-SVWQGIPASPKGAFLSNDAAYTYFYKGTKYWKFDNER 541


>gi|4505219 matrix metalloproteinase 7 preproprotein [Homo sapiens]
          Length = 267

 Score =  257 bits (656), Expect = 2e-68
 Identities = 121/234 (51%), Positives = 154/234 (65%), Gaps = 8/234 (3%)

Query: 41  AQAYLDKYYTNKEGHQIGEMVARGSNSMIRKIKELQAFFGLQVTGKLDQTTMNVIKKPRC 100
           AQ YL ++Y       + +   + +NS+  K+KE+Q FFGL +TG L+   + +++KPRC
Sbjct: 35  AQDYLKRFY-------LYDSETKNANSLEAKLKEMQKFFGLPITGMLNSRVIEIMQKPRC 87

Query: 101 GVPDVANYRLFPGEPKWKKNTLTYRISKYTPSMSSVEVDKAVEMALQAWSSAVPLSFVRI 160
           GVPDVA Y LFP  PKW    +TYRI  YT  +  + VD+ V  AL  W   +PL F ++
Sbjct: 88  GVPDVAEYSLFPNSPKWTSKVVTYRIVSYTRDLPHITVDRLVSKALNMWGKEIPLHFRKV 147

Query: 161 NSGEADIMISFENGDHGDSYPFDGPRGTLAHAFAPGEGLGGDTHFDNAEKWTMGTN-GFN 219
             G ADIMI F  G HGDSYPFDGP  TLAHAFAPG GLGGD HFD  E+WT G++ G N
Sbjct: 148 VWGTADIMIGFARGAHGDSYPFDGPGNTLAHAFAPGTGLGGDAHFDEDERWTDGSSLGIN 207

Query: 220 LFTVAAHEFGHALGLAHSTDPSALMYPTYKYKNPYGFHLPKDDVKGIQALYGPR 273
               A HE GH+LG+ HS+DP+A+MYPTY   +P  F L +DD+KGIQ LYG R
Sbjct: 208 FLYAATHELGHSLGMGHSSDPNAVMYPTYGNGDPQNFKLSQDDIKGIQKLYGKR 261


>gi|11968059 matrix metalloproteinase 25 preproprotein [Homo
           sapiens]
          Length = 562

 Score =  236 bits (601), Expect = 4e-62
 Identities = 167/508 (32%), Positives = 238/508 (46%), Gaps = 44/508 (8%)

Query: 14  IMALKFSTAAPSLVAASPRTWRNNYRLAQAYLDKYYTNKEGHQIGEMVARGSNSMIRKIK 73
           ++AL     AP   A +P+    +  L   +L +Y      H   +   +    +   IK
Sbjct: 7   LLALLLLLLAPP--ARAPKPSAQDVSLGVDWLTRYGYLPPPHP-AQAQLQSPEKLRDAIK 63

Query: 74  ELQAFFGLQVTGKLDQTTMNVIKKPRCGVPDVANY--------RLFPGEPKWKKNTLTYR 125
            +Q F GL  TG++D  T+  ++KPRC +PDV           R       WKK TLT+R
Sbjct: 64  VMQRFAGLPETGRMDPGTVATMRKPRCSLPDVLGVAGLVRRRRRYALSGSVWKKRTLTWR 123

Query: 126 ISKYTPS--MSSVEVDKAVEMALQAWSSAVPLSFVRINSG---EADIMISFENGDHGDSY 180
           +  +  S  +S   V   +  AL AW     L+F  ++S    E DI+I F    H DSY
Sbjct: 124 VRSFPQSSQLSQETVRVLMSYALMAWGMESGLTFHEVDSPQGQEPDILIDFARAFHQDSY 183

Query: 181 PFDGPRGTLAHAFAPGE-GLGGDTHFDNAEKWTMGT---NGFNLFTVAAHEFGHALGLAH 236
           PFDG  GTLAHAF PGE  + GDTHFD+ E WT G+    G +LF VA HEFGHALGL H
Sbjct: 184 PFDGLGGTLAHAFFPGEHPISGDTHFDDEETWTFGSKDGEGTDLFAVAVHEFGHALGLGH 243

Query: 237 STDPSALMYPTYK--YKNPYGFHLPKDDVKGIQALYG----------PRKVFLGKPTLPH 284
           S+ P+++M P Y+    +P  + L +DD  G+Q LYG           RK     P  P 
Sbjct: 244 SSAPNSIMRPFYQGPVGDPDKYRLSQDDRDGLQQLYGKAPQTPYDKPTRKPLAPPPQPPA 303

Query: 285 APHHKPS--IPDLCDSSSSFDAVTMLGKELLLFKDRIFWRRQVHLR-TGIRPSTI---TS 338
           +P H PS  IPD C+   +FDA+  +  E   FK   FWR Q   +    RP+ +     
Sbjct: 304 SPTHSPSFPIPDRCE--GNFDAIANIRGETFFFKGPWFWRLQPSGQLVSPRPARLHRFWE 361

Query: 339 SFPQLMSNVDAAYEVAERGTAYFFKGPHYWITRGFQMQGPPRTIYDFGFPRHVQQIDAAV 398
             P  +  V AAY     G    F GP +W+ +  Q++G  R + + G P   +++DA  
Sbjct: 362 GLPAQVRVVQAAYARHRDGRILLFSGPQFWVFQDRQLEGGARPLTELGLPPG-EEVDAVF 420

Query: 399 YLREPQKTLFFVGDEYYSYDERKRKMEKDYPKNTEEEFSGVNGQIDAAVELNGYIYFFSG 458
              +  KT    G +Y+ YDE   + +  YP++            D  V   G  YFF G
Sbjct: 421 SWPQNGKTYLVRGRQYWRYDEAAARPDPGYPRDLSLWEGAPPSPDDVTVSNAGDTYFFKG 480

Query: 459 PKTYKY---DTEKEDVVSVVKSSSWIGC 483
              +++     + E         +W+ C
Sbjct: 481 AHYWRFPKNSIKTEPDAPQPMGPNWLDC 508


>gi|112382270 matrix metalloproteinase 17 preproprotein [Homo
           sapiens]
          Length = 603

 Score =  234 bits (596), Expect = 2e-61
 Identities = 169/510 (33%), Positives = 244/510 (47%), Gaps = 46/510 (9%)

Query: 9   LAVFLIMALKFSTAAPSLVAASPRTWRNNYRLAQAYLDKY-YTNKEGHQIGEMVARGSNS 67
           L + L +  +   AAP   A +PR    +  L   +L ++ Y        G++  +    
Sbjct: 25  LLLLLALGTRGGCAAP---APAPRA--EDLSLGVEWLSRFGYLPPADPTTGQLQTQ--EE 77

Query: 68  MIRKIKELQAFFGLQVTGKLDQTTMNVIKKPRCGVPDVA------NYRLFPGEPKWKKNT 121
           + + I  +Q F GL+ TG LD+ T+ ++K PRC +PD+         R  P   KW K  
Sbjct: 78  LSKAITAMQQFGGLEATGILDEATLALMKTPRCSLPDLPVLTQARRRRQAPAPTKWNKRN 137

Query: 122 LTYRISKYTPS--MSSVEVDKAVEMALQAWSSAVPLSFVRINSGEADIMISFENGDHGDS 179
           L++R+  +     +    V   +  AL+ WS   PL+F  +    ADI I F   DH D 
Sbjct: 138 LSWRVRTFPRDSPLGHDTVRALMYYALKVWSDIAPLNFHEVAGSAADIQIDFSKADHNDG 197

Query: 180 YPFDGPRGTLAHAFAPG-EGLGGDTHFDNAEKWTM---GTNGFNLFTVAAHEFGHALGLA 235
           YPFDGP GT+AHAF PG     GDTHFD+ E WT      +G +LF VA HEFGHA+GL+
Sbjct: 198 YPFDGPGGTVAHAFFPGHHHTAGDTHFDDDEAWTFRSSDAHGMDLFAVAVHEFGHAIGLS 257

Query: 236 HSTDPSALMYPTYK--YKNPYGFHLPKDDVKGIQALYGPRKVFL------GKPTLPHAPH 287
           H     ++M P Y+    +P  + LP +D   +  LYG R+           P LP  P 
Sbjct: 258 HVAAAHSIMRPYYQGPVGDPLRYGLPYEDKVRVWQLYGVRESVSPTAQPEEPPLLPEPPD 317

Query: 288 HKPSIPDLCD----SSSSFDAVTMLGKELLLFKDRIFWR--RQVHLRTGIRPSTI---TS 338
           ++ S P   D     S+ FDAV  +  E   FK + FWR  R  HL   ++P+ +     
Sbjct: 318 NRSSAPPRKDVPHRCSTHFDAVAQIRGEAFFFKGKYFWRLTRDRHL-VSLQPAQMHRFWR 376

Query: 339 SFPQLMSNVDAAYEVAERGTAYFFKGPHYWITRGFQM-QGPPRTIYDFGFPRHVQQIDAA 397
             P  + +VDA YE        FFKG  YW+ +   + +G PR + DF  P     IDAA
Sbjct: 377 GLPLHLDSVDAVYERTSDHKIVFFKGDRYWVFKDNNVEEGYPRPVSDFSLP--PGGIDAA 434

Query: 398 VYLREPQKTLFFVGDEYYSYDERKRKMEKDYPKNTEEEFSGVNGQIDAAVE-LNGYIYFF 456
                  +T FF    Y+ YD+  R M+  YP  +   + GV   +D A+   +G  YFF
Sbjct: 435 FSWAHNDRTYFFKDQLYWRYDDHTRHMDPGYPAQS-PLWRGVPSTLDDAMRWSDGASYFF 493

Query: 457 SGPKTYK-YDTEKEDVVSVVKSSS--WIGC 483
            G + +K  D E E      +S++  W+ C
Sbjct: 494 RGQEYWKVLDGELEVAPGYPQSTARDWLVC 523


>gi|149999365 matrix metalloproteinase 16 isoform 2 preproprotein
           [Homo sapiens]
          Length = 457

 Score =  226 bits (576), Expect = 4e-59
 Identities = 134/351 (38%), Positives = 185/351 (52%), Gaps = 53/351 (15%)

Query: 61  VARGSNSMIRKIKELQAFFGLQVTGKLDQTTMNVIKKPRCGVPD---------VANYRLF 111
           V R + +M   +  +Q F+G+ +TGK+D+ T++ +KKPRCGVPD         +   R  
Sbjct: 62  VLRSAETMQSALAAMQQFYGINMTGKVDRNTIDWMKKPRCGVPDQTRGSSKFHIRRKRYA 121

Query: 112 PGEPKWKKNTLTYRISKYTPSMSSVEVDKAVEMALQAWSSAVPLSFVRINSGE------- 164
               KW+   +TY I   TP +   E  KA+  A   W +  PL+F  +   E       
Sbjct: 122 LTGQKWQHKHITYSIKNVTPKVGDPETRKAIRRAFDVWQNVTPLTFEEVPYSELENGKRD 181

Query: 165 ADIMISFENGDHGDSYPFDGPRGTLAHAFAPGEGLGGDTHFDNAEKWTMGT---NGFNLF 221
            DI I F +G HGDS PFDG  G LAHA+ PG G+GGDTHFD+ E WT+G    +G +LF
Sbjct: 182 VDITIIFASGFHGDSSPFDGEGGFLAHAYFPGPGIGGDTHFDSDEPWTLGNPNHDGNDLF 241

Query: 222 TVAAHEFGHALGLAHSTDPSALMYPTYKYKNPYGFHLPKDDVKGIQALYG---------- 271
            VA HE GHALGL HS DP+A+M P Y+Y     F LP DD++GIQ +YG          
Sbjct: 242 LVAVHELGHALGLEHSNDPTAIMAPFYQYMETDNFKLPNDDLQGIQKIYGPPDKIPPPTR 301

Query: 272 ---------------PRKVFLGKPTLPHAPHHKPSI----PDLCDSSSSFDAVTMLGKEL 312
                          PRK    KP  P  P  +PS     P++CD   +F+ + +L +E+
Sbjct: 302 PLPTVPPHRSIPPADPRKNDRPKP--PRPPTGRPSYPGAKPNICD--GNFNTLAILRREM 357

Query: 313 LLFKDRIFWRRQVHLRTGIRPSTITSSFPQLMSNVDAAYEVAERGTAYFFK 363
            +FKD+ FWR + +      P  IT  +  L  ++DA YE ++ G   FFK
Sbjct: 358 FVFKDQWFWRVRNNRVMDGYPMQITYFWRGLPPSIDAVYENSD-GNFVFFK 407


>gi|58331148 matrix metalloproteinase 11 preproprotein [Homo
           sapiens]
          Length = 488

 Score =  224 bits (570), Expect = 2e-58
 Identities = 150/399 (37%), Positives = 206/399 (51%), Gaps = 36/399 (9%)

Query: 95  IKKPRCGVPDVAN--------YRLFPGEPKWKKNTLTYRISKYTPSMSSVEVDKAVEMAL 146
           ++ PRCGVPD ++         R      +W+K  LTYRI ++   +   +V + +  AL
Sbjct: 75  LRPPRCGVPDPSDGLSARNRQKRFVLSGGRWEKTDLTYRILRFPWQLVQEQVRQTMAEAL 134

Query: 147 QAWSSAVPLSFVRINSGEADIMISFENGDHGDSYPFDGPRGTLAHAFAPGEGLGGDTHFD 206
           + WS   PL+F  ++ G ADIMI F    HGD  PFDGP G LAHAF P     GD HFD
Sbjct: 135 KVWSDVTPLTFTEVHEGRADIMIDFARYWHGDDLPFDGPGGILAHAFFPKTHREGDVHFD 194

Query: 207 NAEKWTMGTN-GFNLFTVAAHEFGHALGLAHSTDPSALMYPTYKYKNPYGFHLPKDDVKG 265
             E WT+G + G +L  VAAHEFGH LGL H+T   ALM   Y ++  Y   L  DD +G
Sbjct: 195 YDETWTIGDDQGTDLLQVAAHEFGHVLGLQHTTAAKALMSAFYTFR--YPLSLSPDDCRG 252

Query: 266 IQALYG-------PRKVFLGK----PTLPHAPHHKPSIPDLCDSSSSFDAVTMLGKELLL 314
           +Q LYG        R   LG      T   AP    + PD C+  +SFDAV+ +  EL  
Sbjct: 253 VQHLYGQPWPTVTSRTPALGPQAGIDTNEIAPLEPDAPPDACE--ASFDAVSTIRGELFF 310

Query: 315 FKDRIFWR-RQVHLRTGIRPSTITSSFPQLMSNVDAAYEVAERGTAYFFKGPHYWITRGF 373
           FK    WR R   L+ G  P+  +  +  L S VDAA+E A+ G  +FF+G  YW+  G 
Sbjct: 311 FKAGFVWRLRGGQLQPGY-PALASRHWQGLPSPVDAAFEDAQ-GHIWFFQGAQYWVYDGE 368

Query: 374 QMQGPPRTIYDFG---FPRHVQQIDAAVYLREPQKTLFFVGDEYYSYDERKRKMEKDYPK 430
           +    P  + + G   FP H     A V+  E  K  FF G +Y+ +    R+++   P+
Sbjct: 369 KPVLGPAPLTELGLVRFPVHA----ALVWGPEKNKIYFFRGRDYWRFHPSTRRVDSPVPR 424

Query: 431 NTEEEFSGVNGQIDAAV-ELNGYIYFFSGPKTYKYDTEK 468
               ++ GV  +IDAA  + +GY YF  G   +K+D  K
Sbjct: 425 RA-TDWRGVPSEIDAAFQDADGYAYFLRGRLYWKFDPVK 462


>gi|4505213 matrix metalloproteinase 19 isoform rasi-1 preproprotein
           [Homo sapiens]
          Length = 508

 Score =  193 bits (490), Expect = 3e-49
 Identities = 147/409 (35%), Positives = 196/409 (47%), Gaps = 42/409 (10%)

Query: 72  IKELQAFFGLQVTGKLDQTTMNVIKKPRCGVPDVANYR----LFPGEPKWKKNTLTYRIS 127
           ++  Q    L V+G+LD  T   +++PRCG+ D  N +    L  G  +W+K  LT+RI 
Sbjct: 57  LRAFQEASELPVSGQLDDATRARMRQPRCGLEDPFNQKTLKYLLLG--RWRKKHLTFRIL 114

Query: 128 KYTPSMSSVEVDKAVEMALQAWSSAVPLSFVRINSGEADIMISFENGDHGD-SYPFDGPR 186
               ++       A+  A Q WS+  PL+F  + +G ADI +SF        S  FDGP 
Sbjct: 115 NLPSTLPPHTARAALRQAFQDWSNVAPLTFQEVQAGAADIRLSFHGRQSSYCSNTFDGPG 174

Query: 187 GTLAHAFAPGEGLGGDTHFDNAEKWTMGT-NGFNLFTVAAHEFGHALGLAHSTDPSALMY 245
             LAHA  P  G     HFD  E WT GT  G NL  +AAHE GHALGL HS    ALM 
Sbjct: 175 RVLAHADIPELG---SVHFDEDEFWTEGTYRGVNLRIIAAHEVGHALGLGHSRYSQALMA 231

Query: 246 PTYKYKNPYGFHLPKDDVKGIQALYGPRKVFLGK--------PTLPHAPHHKPSIPDLCD 297
           P Y+   P+ F L  DDV GIQALYG +   +          PT+P  P     +PD C 
Sbjct: 232 PVYEGYRPH-FKLHPDDVAGIQALYGKKSPVIRDEEEEETELPTVPPVPTEPSPMPDPC- 289

Query: 298 SSSSFDAVTMLGK--ELLLFKDRIFWRRQVHLRTGIRPS-TITSSFPQLMSNVDAAYEVA 354
            SS  DA+ MLG   +   FK    W       +G  P   +++ +  L  N+DAA    
Sbjct: 290 -SSELDAM-MLGPRGKTYAFKGDYVWTVS---DSGPGPLFRVSALWEGLPGNLDAAVYSP 344

Query: 355 ERGTAYFFKGPHYWITRGFQMQGPPRTIYDFGFPRHVQQI----DAAVYLREPQKTLFFV 410
                +FFKG   W    F+M          GFP+ + ++    DAA+Y    QK   F 
Sbjct: 345 RTQWIHFFKGDKVWRYINFKMSP--------GFPKKLNRVEPNLDAALYWPLNQKVFLFK 396

Query: 411 GDEYYSYDERKRKMEKDYPKNTEEEFSGVNGQIDAAVE-LNGYIYFFSG 458
           G  Y+ +DE  R     YPK  +  F+GV  Q  AA+   +G +YFF G
Sbjct: 397 GSGYWQWDELARTDFSSYPKPIKGLFTGVPNQPSAAMSWQDGRVYFFKG 445



 Score = 30.4 bits (67), Expect = 3.7
 Identities = 20/63 (31%), Positives = 28/63 (44%), Gaps = 3/63 (4%)

Query: 308 LGKELLLFKDRIFWRRQVHLRTGIR--PSTITSSFPQLMSNVDAAYEVAERGTAYFFKGP 365
           L +++ LFK   +W+     RT     P  I   F  + +   AA    + G  YFFKG 
Sbjct: 388 LNQKVFLFKGSGYWQWDELARTDFSSYPKPIKGLFTGVPNQPSAAMSWQD-GRVYFFKGK 446

Query: 366 HYW 368
            YW
Sbjct: 447 VYW 449


>gi|11342666 matrix metalloproteinase 2 isoform a preproprotein
           [Homo sapiens]
          Length = 660

 Score =  189 bits (480), Expect = 5e-48
 Identities = 98/202 (48%), Positives = 122/202 (60%), Gaps = 13/202 (6%)

Query: 17  LKFSTAAPSLVAASPRTW--RNNYRLAQAYLDKYYTNKEGHQIGEMVARGSNSMIRK--I 72
           L  + AAPS +   P     + +  LA  YL+ +Y   +            N  + K  +
Sbjct: 24  LSHAAAAPSPIIKFPGDVAPKTDKELAVQYLNTFYGCPK---------ESCNLFVLKDTL 74

Query: 73  KELQAFFGLQVTGKLDQTTMNVIKKPRCGVPDVANYRLFPGEPKWKKNTLTYRISKYTPS 132
           K++Q FFGL  TG LDQ T+  ++KPRCG PDVANY  FP +PKW KN +TYRI  YTP 
Sbjct: 75  KKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPD 134

Query: 133 MSSVEVDKAVEMALQAWSSAVPLSFVRINSGEADIMISFENGDHGDSYPFDGPRGTLAHA 192
           +    VD A   A Q WS   PL F RI+ GEADIMI+F   +HGD YPFDG  G LAHA
Sbjct: 135 LDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHA 194

Query: 193 FAPGEGLGGDTHFDNAEKWTMG 214
           FAPG G+GGD+HFD+ E WT+G
Sbjct: 195 FAPGTGVGGDSHFDDDELWTLG 216



 Score =  184 bits (468), Expect = 1e-46
 Identities = 107/289 (37%), Positives = 154/289 (53%), Gaps = 17/289 (5%)

Query: 204 HFDNAEKWTMGTN-GFNLFTVAAHEFGHALGLAHSTDPSALMYPTYKYKNPYGFHLPKDD 262
           ++D+  KW    + G++LF VAAHEFGHA+GL HS DP ALM P Y Y     F L +DD
Sbjct: 380 NYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTK--NFRLSQDD 437

Query: 263 VKGIQALYGPRK-VFLGK-PTLPHAPHHKPSIPDLCDSSSSFDAVTMLGKELLLFKDRIF 320
           +KGIQ LYG    + LG  PT    P   P  P++C     FD +  +  E+  FKDR  
Sbjct: 438 IKGIQELYGASPDIDLGTGPT----PTLGPVTPEICKQDIVFDGIAQIRGEIFFFKDRFI 493

Query: 321 WRRQVHLRTGIRPSTITSSFPQLMSNVDAAYEVAERGTAYFFKGPHYWITRGFQMQ-GPP 379
           WR        + P  + + +P+L   +DA YE  +   A FF G  YWI     ++ G P
Sbjct: 494 WRTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYP 553

Query: 380 RTIYDFGFPRHVQQIDAAVYLREPQKTLFFVGDEYYSYDERKRKMEKDYPKNTEEEFSGV 439
           + +   G P  VQ++DAA    + +KT  F GD+++ Y+E K+KM+  +PK   + ++ +
Sbjct: 554 KPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAI 613

Query: 440 NGQIDAAVEL--NGYIYFFSGPKTYKYDTEKEDVVSV---VKSSSWIGC 483
              +DA V+L   G+ YFF G   Y    E + + SV      S W+GC
Sbjct: 614 PDNLDAVVDLQGGGHSYFFKG--AYYLKLENQSLKSVKFGSIKSDWLGC 660


>gi|13236530 matrix metalloproteinase 28 isoform 1 preproprotein
           [Homo sapiens]
          Length = 520

 Score =  188 bits (477), Expect = 1e-47
 Identities = 155/491 (31%), Positives = 221/491 (45%), Gaps = 64/491 (13%)

Query: 41  AQAYLDKY-YTNKEGHQIGEMVARGSNSMIRKIKELQAFFGLQVTGKLDQTTMNVIKKPR 99
           A+A+L+KY Y N++  +     A  S      I+  Q    L V+G LD+ T+  + +PR
Sbjct: 36  AEAFLEKYGYLNEQVPK-----APTSTRFSDAIRAFQWVSQLPVSGVLDRATLRQMTRPR 90

Query: 100 CGVPDVANY----------------------RLFPGEPKWKKNTLTYRISKYTPSMSSVE 137
           CGV D  +Y                      R      KW K  L+YR+  +   +    
Sbjct: 91  CGVTDTNSYAAWAERISDLFARHRTKMRRKKRFAKQGNKWYKQHLSYRLVNWPEHLPEPA 150

Query: 138 VDKAVEMALQAWSSAVPLSFVRINS-GEADIMISFENGDHGDSY--PFDGPRGTLAHAFA 194
           V  AV  A Q WS+   L F    + G ADI ++F  GDH D     FDGP G LAHAF 
Sbjct: 151 VRGAVRAAFQLWSNVSALEFWEAPATGPADIRLTFFQGDHNDGLGNAFDGPGGALAHAFL 210

Query: 195 PGEGLGGDTHFDNAEKWTMGTN-GFNLFTVAAHEFGHALGLAHSTDPSALMYPTYKYKNP 253
           P  G   + HFD  E+W++    G NLF V AHE GH LGL HS  P ALM P YK    
Sbjct: 211 PRRG---EAHFDQDERWSLSRRRGRNLFVVLAHEIGHTLGLTHSPAPRALMAPYYKRLGR 267

Query: 254 YGFHLPKDDVKGIQALYG-----------PRKVFLGKPT----LPHAPHHKPSIPDLCDS 298
               L  DDV  +Q+LYG           P K+F    T     P     +   P  C  
Sbjct: 268 DAL-LSWDDVLAVQSLYGKPLGGSVAVQLPGKLFTDFETWDSYSPQGRRPETQGPKYC-- 324

Query: 299 SSSFDAVTM-LGKELLLFKDRIFWRRQVHLRTGIRPSTITSSFPQLMSNVDAAYEVAERG 357
            SSFDA+T+   ++L +FK   FW           P  +   +  L  N++AA      G
Sbjct: 325 HSSFDAITVDRQQQLYIFKGSHFWEVAADGNVS-EPRPLQERWVGLPPNIEAAAVSLNDG 383

Query: 358 TAYFFKGPHYWITRGFQ-MQGPPRTIYDFGFPRHVQQIDAAVYLREPQKTLFFVGDEYYS 416
             YFFKG   W  RG + + G P+     G PRH    DAA++    ++ + F G  YY 
Sbjct: 384 DFYFFKGGRCWRFRGPKPVWGLPQLCRAGGLPRHP---DAALFFPPLRRLILFKGARYYV 440

Query: 417 YDERKRKMEKDYPKNTEEEFSGVNGQIDAAV-ELNGYIYFFSGPKTYKYDTEKEDVVSVV 475
                 ++E  YP++  +++ G+  ++  A+   +G I FF   + ++ D  K    +  
Sbjct: 441 LARGGLQVEPYYPRSL-QDWGGIPEEVSGALPRPDGSIIFFRDDRYWRLDQAKLQATTSG 499

Query: 476 KSSS---WIGC 483
           + ++   W+GC
Sbjct: 500 RWATELPWMGC 510


>gi|189217853 matrix metalloproteinase 2 isoform b [Homo sapiens]
          Length = 610

 Score =  187 bits (475), Expect = 2e-47
 Identities = 85/143 (59%), Positives = 101/143 (70%)

Query: 72  IKELQAFFGLQVTGKLDQTTMNVIKKPRCGVPDVANYRLFPGEPKWKKNTLTYRISKYTP 131
           +K++Q FFGL  TG LDQ T+  ++KPRCG PDVANY  FP +PKW KN +TYRI  YTP
Sbjct: 24  LKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTP 83

Query: 132 SMSSVEVDKAVEMALQAWSSAVPLSFVRINSGEADIMISFENGDHGDSYPFDGPRGTLAH 191
            +    VD A   A Q WS   PL F RI+ GEADIMI+F   +HGD YPFDG  G LAH
Sbjct: 84  DLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAH 143

Query: 192 AFAPGEGLGGDTHFDNAEKWTMG 214
           AFAPG G+GGD+HFD+ E WT+G
Sbjct: 144 AFAPGTGVGGDSHFDDDELWTLG 166



 Score =  184 bits (468), Expect = 1e-46
 Identities = 107/289 (37%), Positives = 154/289 (53%), Gaps = 17/289 (5%)

Query: 204 HFDNAEKWTMGTN-GFNLFTVAAHEFGHALGLAHSTDPSALMYPTYKYKNPYGFHLPKDD 262
           ++D+  KW    + G++LF VAAHEFGHA+GL HS DP ALM P Y Y     F L +DD
Sbjct: 330 NYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTK--NFRLSQDD 387

Query: 263 VKGIQALYGPRK-VFLGK-PTLPHAPHHKPSIPDLCDSSSSFDAVTMLGKELLLFKDRIF 320
           +KGIQ LYG    + LG  PT    P   P  P++C     FD +  +  E+  FKDR  
Sbjct: 388 IKGIQELYGASPDIDLGTGPT----PTLGPVTPEICKQDIVFDGIAQIRGEIFFFKDRFI 443

Query: 321 WRRQVHLRTGIRPSTITSSFPQLMSNVDAAYEVAERGTAYFFKGPHYWITRGFQMQ-GPP 379
           WR        + P  + + +P+L   +DA YE  +   A FF G  YWI     ++ G P
Sbjct: 444 WRTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYP 503

Query: 380 RTIYDFGFPRHVQQIDAAVYLREPQKTLFFVGDEYYSYDERKRKMEKDYPKNTEEEFSGV 439
           + +   G P  VQ++DAA    + +KT  F GD+++ Y+E K+KM+  +PK   + ++ +
Sbjct: 504 KPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAI 563

Query: 440 NGQIDAAVEL--NGYIYFFSGPKTYKYDTEKEDVVSV---VKSSSWIGC 483
              +DA V+L   G+ YFF G   Y    E + + SV      S W+GC
Sbjct: 564 PDNLDAVVDLQGGGHSYFFKG--AYYLKLENQSLKSVKFGSIKSDWLGC 610


>gi|73808266 matrix metalloproteinase 26 preproprotein [Homo
           sapiens]
          Length = 261

 Score =  183 bits (464), Expect = 3e-46
 Identities = 87/190 (45%), Positives = 114/190 (60%)

Query: 84  TGKLDQTTMNVIKKPRCGVPDVANYRLFPGEPKWKKNTLTYRISKYTPSMSSVEVDKAVE 143
           T  LD     ++ +P CGVPD ++  + PG  KW K+TLTYRI  Y   M    V  ++ 
Sbjct: 66  TDLLDMQMHALLHQPHCGVPDGSDTSISPGRCKWNKHTLTYRIINYPHDMKPSAVKDSIY 125

Query: 144 MALQAWSSAVPLSFVRINSGEADIMISFENGDHGDSYPFDGPRGTLAHAFAPGEGLGGDT 203
            A+  WS+  PL F ++ +G+ADI +SF    H D +PFDGP G L HAF P  G  G  
Sbjct: 126 NAVSIWSNVTPLIFQQVQNGDADIKVSFWQWAHEDGWPFDGPGGILGHAFLPNSGNPGVV 185

Query: 204 HFDNAEKWTMGTNGFNLFTVAAHEFGHALGLAHSTDPSALMYPTYKYKNPYGFHLPKDDV 263
           HFD  E W+    G+NLF VA HE GH+LGL HS + S++MYPTY Y +P  F L  DD+
Sbjct: 186 HFDKNEHWSASDTGYNLFLVATHEIGHSLGLQHSGNQSSIMYPTYWYHDPRTFQLSADDI 245

Query: 264 KGIQALYGPR 273
           + IQ LYG +
Sbjct: 246 QRIQHLYGEK 255


>gi|74272287 matrix metalloproteinase 9 preproprotein [Homo sapiens]
          Length = 707

 Score =  152 bits (384), Expect = 7e-37
 Identities = 86/232 (37%), Positives = 121/232 (52%), Gaps = 17/232 (7%)

Query: 11  VFLIMALKFSTAAP----SLVAASPRTWRNNY---RLAQAYLDKYYTNKEGHQIGEMVAR 63
           V +++ L    AAP    S +   P   R N    +LA+ YL +Y   +     GE  + 
Sbjct: 8   VLVLLVLGCCFAAPRQRQSTLVLFPGDLRTNLTDRQLAEEYLYRYGYTRVAEMRGESKSL 67

Query: 64  GSNSMIRKIKELQAFFGLQVTGKLDQTTMNVIKKPRCGVPDVANYRLFPGEPKWKKNTLT 123
           G   ++     LQ    L  TG+LD  T+  ++ PRCGVPD+  ++ F G+ KW  + +T
Sbjct: 68  GPALLL-----LQKQLSLPETGELDSATLKAMRTPRCGVPDLGRFQTFEGDLKWHHHNIT 122

Query: 124 YRISKYTPSMSSVEVDKAVEMALQAWSSAVPLSFVRINSGEADIMISFENGDHGDSYPFD 183
           Y I  Y+  +    +D A   A   WS+  PL+F R+ S +ADI+I F   +HGD YPFD
Sbjct: 123 YWIQNYSEDLPRAVIDDAFARAFALWSAVTPLTFTRVYSRDADIVIQFGVAEHGDGYPFD 182

Query: 184 GPRGTLAHAFAPGEGLGGDTHFDNAEKWTMGTNGFNLFTVAAHEFGHALGLA 235
           G  G LAHAF PG G+ GD HFD+ E W++G        V    FG+A G A
Sbjct: 183 GKDGLLAHAFPPGPGIQGDAHFDDDELWSLGKG-----VVVPTRFGNADGAA 229



 Score =  110 bits (276), Expect = 2e-24
 Identities = 89/289 (30%), Positives = 127/289 (43%), Gaps = 60/289 (20%)

Query: 203 THFDNAEKWTMGTN-GFNLFTVAAHEFGHALGLAHSTDPSALMYPTYKYKNPYGFHLPKD 261
           ++FD+ +KW    + G++LF VAAHEFGHALGL HS+ P ALMYP Y++    G  L KD
Sbjct: 377 SNFDSDKKWGFCPDQGYSLFLVAAHEFGHALGLDHSSVPEALMYPMYRFTE--GPPLHKD 434

Query: 262 DVKGIQALYGPR--------KVFLGKPTLPHA----------PHHKPS------------ 291
           DV GI+ LYGPR             +PT P            P  +P+            
Sbjct: 435 DVNGIRHLYGPRPEPEPRPPTTTTPQPTAPPTVCPTGPPTVHPSERPTAGPTGPPSAGPT 494

Query: 292 -----------------IPDLCDSSSSFDAVTMLGKELLLFKDRIFWRRQVHLRTGIRPS 334
                            + D C + + FDA+  +G +L LFKD  +WR       G RP 
Sbjct: 495 GPPTAGPSTATTVPLSPVDDAC-NVNIFDAIAEIGNQLYLFKDGKYWR--FSEGRGSRPQ 551

Query: 335 ---TITSSFPQLMSNVDAAYEVAERGTAYFFKGPHYWITRGFQMQGPPRTIYDFGFPRHV 391
               I   +P L   +D+ +E       +FF G   W+  G  + G PR +   G    V
Sbjct: 552 GPFLIADKWPALPRKLDSVFEERLSKKLFFFSGRQVWVYTGASVLG-PRRLDKLGLGADV 610

Query: 392 QQIDAAVYLREPQ-KTLFFVGDEYYSYDERKRKMEKDYPKNTEEEFSGV 439
            Q+  A  LR  + K L F G   + +D + + ++       +  F GV
Sbjct: 611 AQVTGA--LRSGRGKMLLFSGRRLWRFDVKAQMVDPRSASEVDRMFPGV 657


>gi|22218341 matrix metalloproteinase 21 preproprotein [Homo
           sapiens]
          Length = 569

 Score =  127 bits (318), Expect = 3e-29
 Identities = 130/494 (26%), Positives = 197/494 (39%), Gaps = 115/494 (23%)

Query: 67  SMIRKIKELQAFFGLQVTGKLDQTTMNVIKKPRCGVPDV-----------------ANYR 109
           ++   ++  Q    L  +G+LD  T+  + +PRCGVPD+                 A  R
Sbjct: 84  ALAEAVRRFQRANALPASGELDAATLAAMNRPRCGVPDMRPPPPSAPPSPPGPPPRARSR 143

Query: 110 LFPGEP--------------------KWKKNTLTYRI--SKYTPSMSSVEVDKAVEMALQ 147
             P  P                     + K TL++R+     +  +S  +  + V +A +
Sbjct: 144 RSPRAPLSLSRRGWQPRGYPDGGAAQAFSKRTLSWRLLGEALSSQLSVADQRRIVALAFR 203

Query: 148 AWSSAVPLSF---VRINSGEADIMISFENGDH-GDSYPFDGPRGTLAHAFAPGEGLGGDT 203
            WS   PL F   +       DI + F  G H G    FDG     AHA+  G     D 
Sbjct: 204 MWSEVTPLDFREDLAAPGAAVDIKLGFGRGRHLGCPRAFDGSGQEFAHAWRLG-----DI 258

Query: 204 HFDNAEKWTMGTN--GFNLFTVAAHEFGHALGLAHSTDPSALMYPTYKYKNPYGFHLPKD 261
           HFD+ E +T  T+  G +L  VA HE GH LGL H+    ++M P Y  + P  F L   
Sbjct: 259 HFDDDEHFTPPTSDTGISLLKVAVHEIGHVLGLPHTYRTGSIMQPNYIPQEP-AFELDWS 317

Query: 262 DVKGIQALYGPRKVFLGKPTLPHAPHHKPSIPDLCDSS--SSFDAV---------TMLGK 310
           D K IQ LYG                        C+ S  ++FD +          M+  
Sbjct: 318 DRKAIQKLYGS-----------------------CEGSFDTAFDWIRKERNQYGEVMVRF 354

Query: 311 ELLLFKDRIFW---RRQVHLRTGIRPSTITSSFPQLMS-NVDAAYEV--AERGTAYFFKG 364
               F++  +W    R    R G  P  I + +P + + N+DA   +   +R   YFF+G
Sbjct: 355 STYFFRNSWYWLYENRNNRTRYG-DPIQILTGWPGIPTHNIDAFVHIWTWKRDERYFFQG 413

Query: 365 PHYW---------ITRGFQMQGPPRTIYDFGFPRHVQQIDAAVYLREPQKTLFFVGDEYY 415
             YW         +T   Q +  P+ I + GFP     +D A Y R  +   FF     +
Sbjct: 414 NQYWRYDSDKDQALTEDEQGKSYPKLISE-GFPGIPSPLDTAFYDRRQKLIYFFKESLVF 472

Query: 416 SYDERKRKMEKDYPKNTEEEFSGVNGQ------IDAAVELNGY--IYFFSGPKTYKYDTE 467
           ++D  + ++   YPK   E F  V  Q      ID+A     Y  I+FF G   +K   +
Sbjct: 473 AFDVNRNRVLNSYPKRITEVFPAVIPQNHPFRNIDSAYYSYAYNSIFFFKGNAYWKVVND 532

Query: 468 KEDVVSVVKSSSWI 481
           K+      + +SW+
Sbjct: 533 KDK-----QQNSWL 541


>gi|5902004 matrix metalloproteinase 23B precursor [Homo sapiens]
          Length = 390

 Score = 92.4 bits (228), Expect = 8e-19
 Identities = 65/186 (34%), Positives = 89/186 (47%), Gaps = 22/186 (11%)

Query: 103 PDVANYRLFPGEPKWKKNTLTYRISKYTPSMSSV-EVDKAVEMALQAWSSAVPLSFVRIN 161
           P    Y L P   +W    LTYRI  +  ++ S  E  +A+  A + WS   P SF  + 
Sbjct: 74  PRRRRYTLTPARLRWDHFNLTYRILSFPRNLLSPRETRRALAAAFRMWSDVSPFSFREVA 133

Query: 162 SGE-ADIMISFENGDHGDS------YPFDGPRGTLAHAFAPGEGLGGDTHFDNAEKWTMG 214
             + +D+ I F   +H D       + FDGP G LAHAF P  G     HFD++E W +G
Sbjct: 134 PEQPSDLRIGFYPINHTDCLVSALHHCFDGPTGELAHAFFPPHG---GIHFDDSEYWVLG 190

Query: 215 TNGFN---------LFTVAAHEFGHALGLAHSTDPSALMYPTYKYKNPYGFHLPKDDVKG 265
              ++         L  VAAHE GHALGL HS    ALM+     +      L +D++ G
Sbjct: 191 PTRYSWKKGVWLTDLVHVAAHEIGHALGLMHSQHGRALMHLNATLRGWKA--LSQDELWG 248

Query: 266 IQALYG 271
           +  LYG
Sbjct: 249 LHRLYG 254


>gi|169203154 PREDICTED: similar to hCG2042634 [Homo sapiens]
          Length = 358

 Score = 81.3 bits (199), Expect = 2e-15
 Identities = 59/172 (34%), Positives = 79/172 (45%), Gaps = 48/172 (27%)

Query: 44  YLDKYYTN--KEGHQIGEMVARGSNSMIRKIKELQAFFGLQVTGKLDQTTMNVIKKPRCG 101
           YL+  Y N   E +QIG    R S+ ++ K+K++Q FFGL+     DQ            
Sbjct: 147 YLENCYYNLKSEINQIGRQ--RDSSPVLEKLKQMQNFFGLK-----DQN----------- 188

Query: 102 VPDVANYRLFPGEPKWKKNTLTYRISKYTPSMSSVEVDKAVEMALQAWSSAVPLSFVRIN 161
                                      Y P++   +VD+A   A + WS+A  L+F R  
Sbjct: 189 ---------------------------YMPNLPQEDVDRATGKAFELWSNASALTFTRDF 221

Query: 162 SGEADIMISFEN-GDHGDSYPFDGPRGTLAHAFAPGEGLGGDTHFDNAEKWT 212
             E DI++SF    D  D+ PF G  G LAHAF PG G+GGD HFDN E  T
Sbjct: 222 ESEGDIILSFVFLADLHDNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRT 273



 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 31/84 (36%), Positives = 47/84 (55%), Gaps = 1/84 (1%)

Query: 348 DAAYEVAERGTAYFFKGPHYWITRGFQMQGPPRTIYD-FGFPRHVQQIDAAVYLREPQKT 406
           D  ++  E  T  F    H+ +     + G PR +Y  F FP  V++IDAA+Y ++  KT
Sbjct: 263 DVHFDNDETRTKDFRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKT 322

Query: 407 LFFVGDEYYSYDERKRKMEKDYPK 430
            FFV +EY+ YDE  + ++  YPK
Sbjct: 323 HFFVANEYWRYDENMQSVDAGYPK 346


>gi|169203660 PREDICTED: similar to hCG2042634 [Homo sapiens]
          Length = 198

 Score = 78.2 bits (191), Expect = 2e-14
 Identities = 43/101 (42%), Positives = 57/101 (56%), Gaps = 7/101 (6%)

Query: 113 GEPKWKKNTLTYRISKYTPSMSSVEVDKAVEMALQAWSSAVPLSFVRINSGEADIMISFE 172
           G  KW+++        Y P++   +VD+A   A + WS+A  L+F R    E DI++SF 
Sbjct: 19  GIQKWQED------QNYMPNLPQEDVDRATGKAFELWSNASALTFTRDFESEGDIILSFV 72

Query: 173 N-GDHGDSYPFDGPRGTLAHAFAPGEGLGGDTHFDNAEKWT 212
              D  D+ PF G  G LAHAF PG G+GGD HFDN E  T
Sbjct: 73  FLADLHDNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRT 113



 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 31/84 (36%), Positives = 47/84 (55%), Gaps = 1/84 (1%)

Query: 348 DAAYEVAERGTAYFFKGPHYWITRGFQMQGPPRTIYD-FGFPRHVQQIDAAVYLREPQKT 406
           D  ++  E  T  F    H+ +     + G PR +Y  F FP  V++IDAA+Y ++  KT
Sbjct: 103 DVHFDNDETRTKDFRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKT 162

Query: 407 LFFVGDEYYSYDERKRKMEKDYPK 430
            FFV +EY+ YDE  + ++  YPK
Sbjct: 163 HFFVANEYWRYDENMQSVDAGYPK 186


>gi|169202084 PREDICTED: similar to hCG2042634 [Homo sapiens]
          Length = 198

 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 43/101 (42%), Positives = 56/101 (55%), Gaps = 7/101 (6%)

Query: 113 GEPKWKKNTLTYRISKYTPSMSSVEVDKAVEMALQAWSSAVPLSFVRINSGEADIMISFE 172
           G  KW+++        Y P++   +VD+A   A + WS A  L+F R    E DI++SF 
Sbjct: 19  GIQKWQED------QNYMPNLPQEDVDRATGKAFELWSKASALTFTRDFESEGDIILSFV 72

Query: 173 N-GDHGDSYPFDGPRGTLAHAFAPGEGLGGDTHFDNAEKWT 212
              D  D+ PF G  G LAHAF PG G+GGD HFDN E  T
Sbjct: 73  FLADLHDNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRT 113



 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 31/84 (36%), Positives = 47/84 (55%), Gaps = 1/84 (1%)

Query: 348 DAAYEVAERGTAYFFKGPHYWITRGFQMQGPPRTIYD-FGFPRHVQQIDAAVYLREPQKT 406
           D  ++  E  T  F    H+ +     + G PR +Y  F FP  V++IDAA+Y ++  KT
Sbjct: 103 DVHFDNDETRTKDFRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKT 162

Query: 407 LFFVGDEYYSYDERKRKMEKDYPK 430
            FFV +EY+ YDE  + ++  YPK
Sbjct: 163 HFFVANEYWRYDENMQSVDAGYPK 186


>gi|239750339 PREDICTED: hypothetical protein XP_002347374 [Homo
           sapiens]
          Length = 183

 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 40/119 (33%), Positives = 60/119 (50%), Gaps = 7/119 (5%)

Query: 72  IKELQAFFGLQVTGKLDQTTMNVIKKPRCGVPDVANYR----LFPGEPKWKKNTLTYRIS 127
           ++  Q    L V+G+LD  T   +++PRCG+ D  N +    L  G  +W+K  LT+RI 
Sbjct: 57  LRAFQEASELPVSGQLDDATRARMRQPRCGLEDPFNQKTLKYLLLG--RWRKKHLTFRIL 114

Query: 128 KYTPSMSSVEVDKAVEMALQAWSSAVPLSFVRINSGEADIMISFENGDHG-DSYPFDGP 185
               ++       A+  A Q WS+  PL+F  + +G ADI +SF        S  FDGP
Sbjct: 115 NLPSTLPPHTARAALRQAFQDWSNVAPLTFQEVQAGAADIRLSFHGRQSSYCSNTFDGP 173


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.417 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,550,924
Number of Sequences: 37866
Number of extensions: 906905
Number of successful extensions: 2000
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 39
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 1736
Number of HSP's gapped (non-prelim): 80
length of query: 483
length of database: 18,247,518
effective HSP length: 106
effective length of query: 377
effective length of database: 14,233,722
effective search space: 5366113194
effective search space used: 5366113194
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.