Guide to the Human Genome
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Search of human proteins with 45267832

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|45267832 FAST kinase domains 2 [Homo sapiens]
         (710 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|209969832 FAST kinase domains 2 [Homo sapiens]                    1414   0.0  
gi|209969830 FAST kinase domains 2 [Homo sapiens]                    1414   0.0  
gi|45267832 FAST kinase domains 2 [Homo sapiens]                     1414   0.0  
gi|40217812 cell cycle progression 2 protein isoform 1 [Homo sap...    76   1e-13
gi|40068497 FAST kinase domains 3 [Homo sapiens]                       67   7e-11
gi|11141903 FAST kinase domains 5 [Homo sapiens]                       57   5e-08
gi|188497683 FAST kinase domains 1 [Homo sapiens]                      57   5e-08
gi|40217810 cell cycle progression 2 protein isoform 2 [Homo sap...    44   4e-04
gi|13569848 cell cycle progression 2 protein isoform 2 [Homo sap...    44   4e-04
gi|5729822 Fas-activated serine/threonine kinase isoform 1 [Homo...    35   0.24 
gi|39995107 Fas-activated serine/threonine kinase isoform 4 [Hom...    35   0.24 
gi|238859593 UDP-glucose ceramide glucosyltransferase-like 2 [Ho...    32   2.7  
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]     31   3.5  
gi|110347429 mediator complex subunit 12 [Homo sapiens]                31   4.5  
gi|224586823 coiled-coil domain containing 110 isoform b [Homo s...    31   4.5  
gi|4826952 proteasome 26S non-ATPase subunit 5 [Homo sapiens]          31   4.5  
gi|72534720 IQ motif containing H isoform 1 [Homo sapiens]             30   5.9  
gi|195947378 acyl-coenzyme A synthetase ACSM6, mitochondrial [Ho...    30   5.9  

>gi|209969832 FAST kinase domains 2 [Homo sapiens]
          Length = 710

 Score = 1414 bits (3659), Expect = 0.0
 Identities = 710/710 (100%), Positives = 710/710 (100%)

Query: 1   MLTTLKPFGSVSVESKMNNKAGSFFWNLRQFSTLVSTSRTMRLCCLGLCKPKIVHSNWNI 60
           MLTTLKPFGSVSVESKMNNKAGSFFWNLRQFSTLVSTSRTMRLCCLGLCKPKIVHSNWNI
Sbjct: 1   MLTTLKPFGSVSVESKMNNKAGSFFWNLRQFSTLVSTSRTMRLCCLGLCKPKIVHSNWNI 60

Query: 61  LNNFHNRMQSTDIIRYLFQDAFIFKSDVGFQTKGISTLTALRIERLLYAKRLFFDSKQSL 120
           LNNFHNRMQSTDIIRYLFQDAFIFKSDVGFQTKGISTLTALRIERLLYAKRLFFDSKQSL
Sbjct: 61  LNNFHNRMQSTDIIRYLFQDAFIFKSDVGFQTKGISTLTALRIERLLYAKRLFFDSKQSL 120

Query: 121 VPVDKSDDELKKVNLNHEVSNEDVLTKETKPNRISSRKLSEECNSLSDVLDAFSKAPTFP 180
           VPVDKSDDELKKVNLNHEVSNEDVLTKETKPNRISSRKLSEECNSLSDVLDAFSKAPTFP
Sbjct: 121 VPVDKSDDELKKVNLNHEVSNEDVLTKETKPNRISSRKLSEECNSLSDVLDAFSKAPTFP 180

Query: 181 SSNYFTAMWTIAKRLSDDQKRFEKRLMFSHPAFNQLCEHMMREAKIMQYKYLLFSLHAIV 240
           SSNYFTAMWTIAKRLSDDQKRFEKRLMFSHPAFNQLCEHMMREAKIMQYKYLLFSLHAIV
Sbjct: 181 SSNYFTAMWTIAKRLSDDQKRFEKRLMFSHPAFNQLCEHMMREAKIMQYKYLLFSLHAIV 240

Query: 241 KLGIPQNTILVQTLLRVTQERINECDEICLSVLSTVLEAMEPCKNVHVLRTGFRILVDQQ 300
           KLGIPQNTILVQTLLRVTQERINECDEICLSVLSTVLEAMEPCKNVHVLRTGFRILVDQQ
Sbjct: 241 KLGIPQNTILVQTLLRVTQERINECDEICLSVLSTVLEAMEPCKNVHVLRTGFRILVDQQ 300

Query: 301 VWKIEDVFTLQVVMKCIGKDAPIALKRKLEMKALRELDRFSVLNSQHMFEVLAAMNHRSL 360
           VWKIEDVFTLQVVMKCIGKDAPIALKRKLEMKALRELDRFSVLNSQHMFEVLAAMNHRSL
Sbjct: 301 VWKIEDVFTLQVVMKCIGKDAPIALKRKLEMKALRELDRFSVLNSQHMFEVLAAMNHRSL 360

Query: 361 ILLDECSKVVLDNIHGCPLRIMINILQSCKDLQYHNLDLFKGLADYVAATFDIWKFRKVL 420
           ILLDECSKVVLDNIHGCPLRIMINILQSCKDLQYHNLDLFKGLADYVAATFDIWKFRKVL
Sbjct: 361 ILLDECSKVVLDNIHGCPLRIMINILQSCKDLQYHNLDLFKGLADYVAATFDIWKFRKVL 420

Query: 421 FILILFENLGFRPVGLMDLFMKRIVEDPESLNMKNILSILHTYSSLNHVYKCQNKEQFVE 480
           FILILFENLGFRPVGLMDLFMKRIVEDPESLNMKNILSILHTYSSLNHVYKCQNKEQFVE
Sbjct: 421 FILILFENLGFRPVGLMDLFMKRIVEDPESLNMKNILSILHTYSSLNHVYKCQNKEQFVE 480

Query: 481 VMASALTGYLHTISSENLLDAVYSFCLMNYFPLAPFNQLLQKDIISELLTSDDMKNAYKL 540
           VMASALTGYLHTISSENLLDAVYSFCLMNYFPLAPFNQLLQKDIISELLTSDDMKNAYKL
Sbjct: 481 VMASALTGYLHTISSENLLDAVYSFCLMNYFPLAPFNQLLQKDIISELLTSDDMKNAYKL 540

Query: 541 HTLDTCLKLDDTVYLRDIALSLPQLPRELPSSHTNAKVAEVLSSLLGGEGHFSKDVHLPH 600
           HTLDTCLKLDDTVYLRDIALSLPQLPRELPSSHTNAKVAEVLSSLLGGEGHFSKDVHLPH
Sbjct: 541 HTLDTCLKLDDTVYLRDIALSLPQLPRELPSSHTNAKVAEVLSSLLGGEGHFSKDVHLPH 600

Query: 601 NYHIDFEIRMDTNRNQVLPLSDVDTTSATDIQRVAVLCVSRSAYCLGSSHPRGFLAMKMR 660
           NYHIDFEIRMDTNRNQVLPLSDVDTTSATDIQRVAVLCVSRSAYCLGSSHPRGFLAMKMR
Sbjct: 601 NYHIDFEIRMDTNRNQVLPLSDVDTTSATDIQRVAVLCVSRSAYCLGSSHPRGFLAMKMR 660

Query: 661 HLNAMGFHVILVNNWEMDKLEMEDAVTFLKTKIYSVEALPVAAVNVQSTQ 710
           HLNAMGFHVILVNNWEMDKLEMEDAVTFLKTKIYSVEALPVAAVNVQSTQ
Sbjct: 661 HLNAMGFHVILVNNWEMDKLEMEDAVTFLKTKIYSVEALPVAAVNVQSTQ 710


>gi|209969830 FAST kinase domains 2 [Homo sapiens]
          Length = 710

 Score = 1414 bits (3659), Expect = 0.0
 Identities = 710/710 (100%), Positives = 710/710 (100%)

Query: 1   MLTTLKPFGSVSVESKMNNKAGSFFWNLRQFSTLVSTSRTMRLCCLGLCKPKIVHSNWNI 60
           MLTTLKPFGSVSVESKMNNKAGSFFWNLRQFSTLVSTSRTMRLCCLGLCKPKIVHSNWNI
Sbjct: 1   MLTTLKPFGSVSVESKMNNKAGSFFWNLRQFSTLVSTSRTMRLCCLGLCKPKIVHSNWNI 60

Query: 61  LNNFHNRMQSTDIIRYLFQDAFIFKSDVGFQTKGISTLTALRIERLLYAKRLFFDSKQSL 120
           LNNFHNRMQSTDIIRYLFQDAFIFKSDVGFQTKGISTLTALRIERLLYAKRLFFDSKQSL
Sbjct: 61  LNNFHNRMQSTDIIRYLFQDAFIFKSDVGFQTKGISTLTALRIERLLYAKRLFFDSKQSL 120

Query: 121 VPVDKSDDELKKVNLNHEVSNEDVLTKETKPNRISSRKLSEECNSLSDVLDAFSKAPTFP 180
           VPVDKSDDELKKVNLNHEVSNEDVLTKETKPNRISSRKLSEECNSLSDVLDAFSKAPTFP
Sbjct: 121 VPVDKSDDELKKVNLNHEVSNEDVLTKETKPNRISSRKLSEECNSLSDVLDAFSKAPTFP 180

Query: 181 SSNYFTAMWTIAKRLSDDQKRFEKRLMFSHPAFNQLCEHMMREAKIMQYKYLLFSLHAIV 240
           SSNYFTAMWTIAKRLSDDQKRFEKRLMFSHPAFNQLCEHMMREAKIMQYKYLLFSLHAIV
Sbjct: 181 SSNYFTAMWTIAKRLSDDQKRFEKRLMFSHPAFNQLCEHMMREAKIMQYKYLLFSLHAIV 240

Query: 241 KLGIPQNTILVQTLLRVTQERINECDEICLSVLSTVLEAMEPCKNVHVLRTGFRILVDQQ 300
           KLGIPQNTILVQTLLRVTQERINECDEICLSVLSTVLEAMEPCKNVHVLRTGFRILVDQQ
Sbjct: 241 KLGIPQNTILVQTLLRVTQERINECDEICLSVLSTVLEAMEPCKNVHVLRTGFRILVDQQ 300

Query: 301 VWKIEDVFTLQVVMKCIGKDAPIALKRKLEMKALRELDRFSVLNSQHMFEVLAAMNHRSL 360
           VWKIEDVFTLQVVMKCIGKDAPIALKRKLEMKALRELDRFSVLNSQHMFEVLAAMNHRSL
Sbjct: 301 VWKIEDVFTLQVVMKCIGKDAPIALKRKLEMKALRELDRFSVLNSQHMFEVLAAMNHRSL 360

Query: 361 ILLDECSKVVLDNIHGCPLRIMINILQSCKDLQYHNLDLFKGLADYVAATFDIWKFRKVL 420
           ILLDECSKVVLDNIHGCPLRIMINILQSCKDLQYHNLDLFKGLADYVAATFDIWKFRKVL
Sbjct: 361 ILLDECSKVVLDNIHGCPLRIMINILQSCKDLQYHNLDLFKGLADYVAATFDIWKFRKVL 420

Query: 421 FILILFENLGFRPVGLMDLFMKRIVEDPESLNMKNILSILHTYSSLNHVYKCQNKEQFVE 480
           FILILFENLGFRPVGLMDLFMKRIVEDPESLNMKNILSILHTYSSLNHVYKCQNKEQFVE
Sbjct: 421 FILILFENLGFRPVGLMDLFMKRIVEDPESLNMKNILSILHTYSSLNHVYKCQNKEQFVE 480

Query: 481 VMASALTGYLHTISSENLLDAVYSFCLMNYFPLAPFNQLLQKDIISELLTSDDMKNAYKL 540
           VMASALTGYLHTISSENLLDAVYSFCLMNYFPLAPFNQLLQKDIISELLTSDDMKNAYKL
Sbjct: 481 VMASALTGYLHTISSENLLDAVYSFCLMNYFPLAPFNQLLQKDIISELLTSDDMKNAYKL 540

Query: 541 HTLDTCLKLDDTVYLRDIALSLPQLPRELPSSHTNAKVAEVLSSLLGGEGHFSKDVHLPH 600
           HTLDTCLKLDDTVYLRDIALSLPQLPRELPSSHTNAKVAEVLSSLLGGEGHFSKDVHLPH
Sbjct: 541 HTLDTCLKLDDTVYLRDIALSLPQLPRELPSSHTNAKVAEVLSSLLGGEGHFSKDVHLPH 600

Query: 601 NYHIDFEIRMDTNRNQVLPLSDVDTTSATDIQRVAVLCVSRSAYCLGSSHPRGFLAMKMR 660
           NYHIDFEIRMDTNRNQVLPLSDVDTTSATDIQRVAVLCVSRSAYCLGSSHPRGFLAMKMR
Sbjct: 601 NYHIDFEIRMDTNRNQVLPLSDVDTTSATDIQRVAVLCVSRSAYCLGSSHPRGFLAMKMR 660

Query: 661 HLNAMGFHVILVNNWEMDKLEMEDAVTFLKTKIYSVEALPVAAVNVQSTQ 710
           HLNAMGFHVILVNNWEMDKLEMEDAVTFLKTKIYSVEALPVAAVNVQSTQ
Sbjct: 661 HLNAMGFHVILVNNWEMDKLEMEDAVTFLKTKIYSVEALPVAAVNVQSTQ 710


>gi|45267832 FAST kinase domains 2 [Homo sapiens]
          Length = 710

 Score = 1414 bits (3659), Expect = 0.0
 Identities = 710/710 (100%), Positives = 710/710 (100%)

Query: 1   MLTTLKPFGSVSVESKMNNKAGSFFWNLRQFSTLVSTSRTMRLCCLGLCKPKIVHSNWNI 60
           MLTTLKPFGSVSVESKMNNKAGSFFWNLRQFSTLVSTSRTMRLCCLGLCKPKIVHSNWNI
Sbjct: 1   MLTTLKPFGSVSVESKMNNKAGSFFWNLRQFSTLVSTSRTMRLCCLGLCKPKIVHSNWNI 60

Query: 61  LNNFHNRMQSTDIIRYLFQDAFIFKSDVGFQTKGISTLTALRIERLLYAKRLFFDSKQSL 120
           LNNFHNRMQSTDIIRYLFQDAFIFKSDVGFQTKGISTLTALRIERLLYAKRLFFDSKQSL
Sbjct: 61  LNNFHNRMQSTDIIRYLFQDAFIFKSDVGFQTKGISTLTALRIERLLYAKRLFFDSKQSL 120

Query: 121 VPVDKSDDELKKVNLNHEVSNEDVLTKETKPNRISSRKLSEECNSLSDVLDAFSKAPTFP 180
           VPVDKSDDELKKVNLNHEVSNEDVLTKETKPNRISSRKLSEECNSLSDVLDAFSKAPTFP
Sbjct: 121 VPVDKSDDELKKVNLNHEVSNEDVLTKETKPNRISSRKLSEECNSLSDVLDAFSKAPTFP 180

Query: 181 SSNYFTAMWTIAKRLSDDQKRFEKRLMFSHPAFNQLCEHMMREAKIMQYKYLLFSLHAIV 240
           SSNYFTAMWTIAKRLSDDQKRFEKRLMFSHPAFNQLCEHMMREAKIMQYKYLLFSLHAIV
Sbjct: 181 SSNYFTAMWTIAKRLSDDQKRFEKRLMFSHPAFNQLCEHMMREAKIMQYKYLLFSLHAIV 240

Query: 241 KLGIPQNTILVQTLLRVTQERINECDEICLSVLSTVLEAMEPCKNVHVLRTGFRILVDQQ 300
           KLGIPQNTILVQTLLRVTQERINECDEICLSVLSTVLEAMEPCKNVHVLRTGFRILVDQQ
Sbjct: 241 KLGIPQNTILVQTLLRVTQERINECDEICLSVLSTVLEAMEPCKNVHVLRTGFRILVDQQ 300

Query: 301 VWKIEDVFTLQVVMKCIGKDAPIALKRKLEMKALRELDRFSVLNSQHMFEVLAAMNHRSL 360
           VWKIEDVFTLQVVMKCIGKDAPIALKRKLEMKALRELDRFSVLNSQHMFEVLAAMNHRSL
Sbjct: 301 VWKIEDVFTLQVVMKCIGKDAPIALKRKLEMKALRELDRFSVLNSQHMFEVLAAMNHRSL 360

Query: 361 ILLDECSKVVLDNIHGCPLRIMINILQSCKDLQYHNLDLFKGLADYVAATFDIWKFRKVL 420
           ILLDECSKVVLDNIHGCPLRIMINILQSCKDLQYHNLDLFKGLADYVAATFDIWKFRKVL
Sbjct: 361 ILLDECSKVVLDNIHGCPLRIMINILQSCKDLQYHNLDLFKGLADYVAATFDIWKFRKVL 420

Query: 421 FILILFENLGFRPVGLMDLFMKRIVEDPESLNMKNILSILHTYSSLNHVYKCQNKEQFVE 480
           FILILFENLGFRPVGLMDLFMKRIVEDPESLNMKNILSILHTYSSLNHVYKCQNKEQFVE
Sbjct: 421 FILILFENLGFRPVGLMDLFMKRIVEDPESLNMKNILSILHTYSSLNHVYKCQNKEQFVE 480

Query: 481 VMASALTGYLHTISSENLLDAVYSFCLMNYFPLAPFNQLLQKDIISELLTSDDMKNAYKL 540
           VMASALTGYLHTISSENLLDAVYSFCLMNYFPLAPFNQLLQKDIISELLTSDDMKNAYKL
Sbjct: 481 VMASALTGYLHTISSENLLDAVYSFCLMNYFPLAPFNQLLQKDIISELLTSDDMKNAYKL 540

Query: 541 HTLDTCLKLDDTVYLRDIALSLPQLPRELPSSHTNAKVAEVLSSLLGGEGHFSKDVHLPH 600
           HTLDTCLKLDDTVYLRDIALSLPQLPRELPSSHTNAKVAEVLSSLLGGEGHFSKDVHLPH
Sbjct: 541 HTLDTCLKLDDTVYLRDIALSLPQLPRELPSSHTNAKVAEVLSSLLGGEGHFSKDVHLPH 600

Query: 601 NYHIDFEIRMDTNRNQVLPLSDVDTTSATDIQRVAVLCVSRSAYCLGSSHPRGFLAMKMR 660
           NYHIDFEIRMDTNRNQVLPLSDVDTTSATDIQRVAVLCVSRSAYCLGSSHPRGFLAMKMR
Sbjct: 601 NYHIDFEIRMDTNRNQVLPLSDVDTTSATDIQRVAVLCVSRSAYCLGSSHPRGFLAMKMR 660

Query: 661 HLNAMGFHVILVNNWEMDKLEMEDAVTFLKTKIYSVEALPVAAVNVQSTQ 710
           HLNAMGFHVILVNNWEMDKLEMEDAVTFLKTKIYSVEALPVAAVNVQSTQ
Sbjct: 661 HLNAMGFHVILVNNWEMDKLEMEDAVTFLKTKIYSVEALPVAAVNVQSTQ 710


>gi|40217812 cell cycle progression 2 protein isoform 1 [Homo
           sapiens]
          Length = 631

 Score = 75.9 bits (185), Expect = 1e-13
 Identities = 104/525 (19%), Positives = 217/525 (41%), Gaps = 28/525 (5%)

Query: 199 QKRFEKRLMFSHPAFNQLCEHMMREAKIMQYKYLLFSLHAIVKLGIPQNTILVQTLLRVT 258
           +K  +K L+     F+QL   +  +   + +  L   L ++  LGIP+ +  +Q++ +  
Sbjct: 113 EKPEDKGLLIQDAHFHQLLCLLNSQIASVWHGTLSKLLGSLYALGIPKASKELQSVEQEV 172

Query: 259 QERINECDEICLSVLSTVLEAMEPCKNVHVLRTGFRILVDQQVWKIEDVFTLQVVMKCIG 318
           + R+ +     L+ L+     +   ++   L       ++++  +IED  TL  VM  +G
Sbjct: 173 RWRMRKLKYKHLAFLAESCATLSQEQHSQELLAELLTHLERRWTEIEDSHTLVTVMMKVG 232

Query: 319 KDAPIALKRKLEMKALRELDRFSVLNSQHMFEVLAAMNHRSLILLDECSKVVLDNIHGCP 378
             +   L  +LE K L  ++ F     + +  +LAA + RS+ LL   S  ++       
Sbjct: 233 HLSE-PLMNRLEDKCLELVEHFGPNELRKVLVMLAAQSRRSVPLLRAISYHLVQKPFSLT 291

Query: 379 LRIMINILQSCKDLQYHNLDLFKGLADYVAATFDIWKFRKVLFILILFENLGFRPVGLMD 438
             +++++  +   L +H   + + LA  + +        +V      F  L +  + L +
Sbjct: 292 KDVLLDVAYAYGKLSFHQTQVSQRLATDLLSLMPSLTSGEVAHCAKSFALLKWLSLPLFE 351

Query: 439 LFMKRIVEDPESLNMKNILSILHTYSSLNHVYKCQNKEQFVEVMASALTGYLHTISSENL 498
            F + ++   + + + ++ S+L  ++ LN  +    ++QF  ++   L   L  +     
Sbjct: 352 AFAQHVLNRAQDITLPHLCSVLLAFARLN--FHPDQEDQFFSLVHEKLGSELPGLEPALQ 409

Query: 499 LDAVYSFCLMNYFPLAPFNQLLQKDIISELLTSDDMKNAYKLHTLDTCLKLDDTVYLRDI 558
           +D V++ C++     A    +L  +   + L     K+    +T    L ++ T  L   
Sbjct: 410 VDLVWALCVLQQAREAELQAVLHPEFHIQFLGGKSQKDQ---NTFQKLLHINATALLEYP 466

Query: 559 ALSLPQLPRELPSSHTNA----------KVAEVLSSLLGGEGHFSKDVHLPHNYHIDFEI 608
             S P LP    +   +A          ++ E L  LLG     S +V   + + +D E+
Sbjct: 467 EYSGPLLPASAVAPGPSALDRKVTPLQKELQETLKGLLGSADKGSLEVATQYGWVLDAEV 526

Query: 609 RMDTNRNQVLPLSDV----------DTTSATDIQRVAVLCVSRSAYCLGSSHPRGFLAMK 658
            +D++  + LP+ D             +     +R+A L      +   S    G   + 
Sbjct: 527 LLDSD-GEFLPVRDFVAPHLAQPTGSQSPPPGSKRLAFLRWEFPNFNSRSKDLLGRFVLA 585

Query: 659 MRHLNAMGFHVILVNNWEMDKLEME-DAVTFLKTKIYSVEALPVA 702
            RH+ A GF ++ V  +E  +L+ E     +LK K+    A  +A
Sbjct: 586 RRHIVAAGFLIVDVPFYEWLELKSEWQKGAYLKDKMRKAVAEELA 630


>gi|40068497 FAST kinase domains 3 [Homo sapiens]
          Length = 662

 Score = 66.6 bits (161), Expect = 7e-11
 Identities = 116/581 (19%), Positives = 231/581 (39%), Gaps = 33/581 (5%)

Query: 138 EVSNEDVLTKETK--PNRISSRKLSEECNSLSDVLDAFSKAPTFPSSNYFTAMWTIAKRL 195
           +VS+ D L +  K   +++  R+LS   +S  +VL   S   T P +    A+  I +  
Sbjct: 83  QVSDCDRLEQNVKNEESQMFYRRLSNLTSS-EEVLSFISTMETLPDTMAAGALQRICEVE 141

Query: 196 SDDQKRFEKRLMFSHPAFNQLCEHMMREAKIMQYKYLLFSLHAIVKLGIPQNTILVQTLL 255
             D  +   + +  +  F  LC    +E   +    L+ +L A++ L +   + L+  L+
Sbjct: 142 KKDGDQGLPKEILENSIFQALCFQFEKEPSQLSNTSLVTALQALILLHVDPQSSLLLNLV 201

Query: 256 RVTQERIN----ECDEICLSVLSTVLEAMEPCKNVHVLRTGFRILVDQQVWKIEDVFTL- 310
              Q R+     E   +C+   S +      C  + ++    +     + +  ED+  L 
Sbjct: 202 AECQNRLRKGGMEVRNLCILGESLITLHSSGCVTLELIINQLQG-EKLETFTPEDIVALY 260

Query: 311 QVVMKCIGK-DAPIALKRKLEMKALRELDRFSVLNSQHMFEVLAAMNH-RSLILLDECSK 368
           +++  C  K D       K+   +L  +   S      M   L  ++  ++  L+ +  K
Sbjct: 261 RILQACTEKVDEHQTFLNKINNFSLSIVSNLSPKLISQMLTALVVLDQSQAFPLIIKLGK 320

Query: 369 VVLDNIHGCPLRIMINILQSCKDLQYHNLDLFKGLADYVAATFDIWKFRKVLFILILFEN 428
            V+ ++       +  +L++     +H+    K L   VAA         V  ++     
Sbjct: 321 YVVRHVPHFTNEELRRVLEAFIYFGHHDTFFTKALEHRVAAVCLTLDPEVVCRVMEYCSR 380

Query: 429 LGFRPVGLMDLFMKRIVEDPESLNMKNILSILHTYSSLNHVYKCQNKEQFVEVMASALTG 488
                  +++   +  V   E  + + I +++  +  LN  Y   N       + + L  
Sbjct: 381 ELILSKPILNAVAETFVCQTEKFSPRQISALMEPFGKLN--YLPPNASALFRKLENVLFT 438

Query: 489 YLHTISSENLLDAVYSFCLMNYFPLAPFNQLLQKDIISELLTSD---DMKNAYKLHTLDT 545
           + +    ++LL  ++S  L    P+    ++ +   +  L   +   D  +  +L  L  
Sbjct: 439 HFNYFPPKSLLKLLHSCSLNECHPVNFLAKIFKPLFLQRLQGKESHLDTLSRAQLTQLFL 498

Query: 546 CLKLDDTVYLRDIALSLPQLPR--------ELPSSHTNAKVAEV-LSSLLGGEGHFSKDV 596
              L+   Y     L   Q+          E P      +  ++ L++LLG   +F+  V
Sbjct: 499 ASVLECPFYKGPKLLPKYQVKSFLTPCCSLETPVDSQLYRYVKIGLTNLLGARLYFAPKV 558

Query: 597 HLPHNYHIDFEIRMDTNRNQVLPLSDVDTTSATDIQRVAVLCVSR-SAYCLGSSHPRGFL 655
             P+ Y ID EI++D     VLP     +T+  DI +   LC+     +C  S H  G  
Sbjct: 559 LTPYCYTIDVEIKLD-EEGFVLP-----STANEDIHKRIALCIDGPKRFCSNSKHLLGKE 612

Query: 656 AMKMRHLNAMGFHVILVNNWEMDKLE-MEDAVTFLKTKIYS 695
           A+K RHL  +G+ V+ +   E+  L+   + V +L+ K++S
Sbjct: 613 AIKQRHLQLLGYQVVQIPYHEIGMLKSRRELVEYLQRKLFS 653


>gi|11141903 FAST kinase domains 5 [Homo sapiens]
          Length = 764

 Score = 57.4 bits (137), Expect = 5e-08
 Identities = 86/435 (19%), Positives = 182/435 (41%), Gaps = 44/435 (10%)

Query: 206 LMFSHPAFNQLCEHMMREAKIMQYKYLLFSLHAIVKLGIPQNTILVQTLLRVTQERINEC 265
           ++    +F  LC+  +++ ++   + L+  L A V LGIP +     ++L V + +   C
Sbjct: 180 VLLGSTSFALLCQLSVKKIQLFDTQDLINVLKAFVILGIPHS----HSMLDVYETKC--C 233

Query: 266 DEICLSVLSTVLEAMEPCKNVHVLRTGFRILVDQQV---WKIEDVFTLQVVMKCIGKDAP 322
            ++    +  +L   +  + +      F  +    +   WK   +  L  ++  IG++  
Sbjct: 234 HQVWEMNMDQLLLVADLWRYLGRKVPRFLNIFSSYLNLHWKDLSLSQLVHLIYVIGENRQ 293

Query: 323 IA--LKRKLEMKALRELDRFSVLNSQHMFEVLAAMNHRSLILLDECSKVVLD----NIHG 376
           ++  L +KLE   L+ +D   ++N + +  +       S  L +   + + D    NI  
Sbjct: 294 VSQDLMQKLESLILKYID---LINLEEVGTICLGFFKSSTNLSEFVMRKIGDLACANIQH 350

Query: 377 CPLRIMINILQSCKDLQYHNLDLFKGLADYVAATFDIWKFRKVLFILILFENLGFRPVGL 436
              R ++NI++  +     +++  K + +           + V+ + +    L F   G+
Sbjct: 351 LSSRSLVNIVKMFRFTHVDHINFMKQIGEIAPQRIPSLGVQGVMHLTLYCSALRFLNEGV 410

Query: 437 MDLFMKRIVEDPESLNMKNILSILHTYSSLNHVYKCQNKEQFVEVMASALTGYLHTISS- 495
           M+     +         K++  IL ++ +LN  YK  N E+F   + S +   +   +  
Sbjct: 411 MNAVAASLPPRVAHCRSKDVAKILWSFGTLN--YKPPNAEEFYSSLISEIHRKMPEFNQY 468

Query: 496 -ENLLDAVYSFCLMNYFP-------LAP-FNQLLQK----DIISELLTSDDMKNA----Y 538
            E+L   +     + YFP       L+P F +L Q+    D++ EL T D         Y
Sbjct: 469 PEHLPTCLLGLAFLEYFPVELIDFALSPGFVRLAQERTKFDLLKELYTLDGTVGIECPDY 528

Query: 539 KLHTLDTCLKLDDTVYLRDIALSLPQLPRELPSSHTNAKVAEVLSSLLGGEGHFSKDVHL 598
           + + L T L+ + +  L  +A       +++ S     +   +L ++LGG  +    + L
Sbjct: 529 RGNRLSTHLQQEGSELLWYLA------EKDMNSKPEFLETVFLLETMLGGPQYVKHHMIL 582

Query: 599 PHNYHIDFEIRMDTN 613
           PH    D E+++D N
Sbjct: 583 PHTRSSDLEVQLDVN 597



 Score = 36.6 bits (83), Expect = 0.083
 Identities = 21/70 (30%), Positives = 36/70 (51%), Gaps = 3/70 (4%)

Query: 629 TDIQRVAVLCVSRSAYCLGSSHPRGFLAMKMRHLNAMGFHVILVNNWE---MDKLEMEDA 685
           T   ++AV   +R+ YC GS    G   MK R L  +G+ V+ ++ WE   + K    + 
Sbjct: 692 TPRMKLAVQFTNRNQYCYGSRDLLGLHNMKRRQLARLGYRVVELSYWEWLPLLKRTRLEK 751

Query: 686 VTFLKTKIYS 695
           + FL  K+++
Sbjct: 752 LAFLHEKVFT 761


>gi|188497683 FAST kinase domains 1 [Homo sapiens]
          Length = 847

 Score = 57.4 bits (137), Expect = 5e-08
 Identities = 64/287 (22%), Positives = 116/287 (40%), Gaps = 54/287 (18%)

Query: 436 LMDLFMKRIVEDPESLNMKNILSILHTYSSLNHVYKCQNKEQFVEVMASALTGYLHTISS 495
           L+D      V+  E ++   I +I+  +S LN  Y    +++F+      L  YL  +  
Sbjct: 553 LLDRIASVAVQQIEKIHPFTIPAIIRPFSVLN--YDPPQRDEFLGTCVQHLNSYLGILDP 610

Query: 496 ENLLDAVYSFCLMNYFP----LAPFNQLLQKDIISEL-LTSDDMKNAYKLHTLDTCLKLD 550
             L+   +S   + YFP     A FN      + S+L + S       + H ++      
Sbjct: 611 FILVFLGFSLATLEYFPEDLLKAIFNIKFLARLDSQLEILSPSRSARVQFHLMELN---- 666

Query: 551 DTVYLRDIALSLPQLPRELPSSH----------------TNAKVAEVLSSLLGGEGHFSK 594
                R + L  P+   ++P  H                T  ++ ++L+ +LGG      
Sbjct: 667 -----RSVCLECPEF--QIPWFHDRFCQQYNKGIGGMDGTQQQIFKMLAEVLGGINCVKA 719

Query: 595 DVHLPHNYHIDFEIRMDTNRNQVLP----------LSDVDTTSATDI---------QRVA 635
            V  P+ + +DFE  +D  R + LP          L ++   S  +I         +R+A
Sbjct: 720 SVLTPYYHKVDFECILD-KRKKPLPYGSHNIALGQLPEMPWESNIEIVGSRLPPGAERIA 778

Query: 636 VLCVSRSAYCLGSSHPRGFLAMKMRHLNAMGFHVILVNNWEMDKLEM 682
           +  +   A C    H +G  AMK RHL  +G+ VI ++ +E + + +
Sbjct: 779 LEFLDSKALCRNIPHMKGKSAMKKRHLEILGYRVIQISQFEWNSMAL 825



 Score = 35.0 bits (79), Expect = 0.24
 Identities = 47/217 (21%), Positives = 87/217 (40%), Gaps = 7/217 (3%)

Query: 185 FTAMWTIAKRLSDDQKRFEKRLMFSHPAFNQLCEHMMREAKIMQYKYLLFSLHAIVKLGI 244
           F  +W + K+ +   K  E   +  HP F  L      + K+M    L+  L+   +   
Sbjct: 72  FDMLWKLQKQKTSLLKNAE--YVRDHPQFLTLHNLATNKFKLMNDDTLVNVLYVTQQFAG 129

Query: 245 PQNTILVQTLLRVTQERINECDEICLSVLSTVLEAMEPCKNVHVLRTGFRILVDQQVWKI 304
             +  LV+ L+     R+   D   LS  S+ L           L      +V + +   
Sbjct: 130 EAHDPLVEALVTEAWRRLERFDIKLLSEFSSCLADQH--LYFSPLMGKIADIVHRNLETT 187

Query: 305 EDVFTLQVVMKCIGKDAPIALKRKLEMKA---LRELDRFSVLNSQHMFEVLAAMNHRSLI 361
           +D+ +L V+M  I        +++L  K       +D   V  ++ + + L  + +R   
Sbjct: 188 QDLSSLSVLMVNISSLISRHFQQQLVNKTELLFDTIDSSEVNVAKSIAKFLRNVRYRYQP 247

Query: 362 LLDECSKVVLDNIHGCPLRIMINILQSCKDLQYHNLD 398
           LL+ C+ V L N+    L  +  IL   K LQ+++ +
Sbjct: 248 LLERCNNVFLSNVDHLDLDSISKILSVYKFLQFNSFE 284


>gi|40217810 cell cycle progression 2 protein isoform 2 [Homo
           sapiens]
          Length = 521

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 57/282 (20%), Positives = 113/282 (40%), Gaps = 27/282 (9%)

Query: 442 KRIVEDPESLNMKNILSILHTYSSLNHVYKCQNKEQFVEVMASALTGYLHTISSENLLDA 501
           K ++   + + + ++ S+L  ++ LN  +    ++QF  ++   L   L  +     +D 
Sbjct: 245 KHVLNRAQDITLPHLCSVLLAFARLN--FHPDQEDQFFSLVHEKLGSELPGLEPALQVDL 302

Query: 502 VYSFCLMNYFPLAPFNQLLQKDIISELLTSDDMKNAYKLHTLDTCLKLDDTVYLRDIALS 561
           V++ C++     A    +L  +   + L     K+    +T    L ++ T  L     S
Sbjct: 303 VWALCVLQQAREAELQAVLHPEFHIQFLGGKSQKDQ---NTFQKLLHINATALLEYPEYS 359

Query: 562 LPQLPRELPSSHTNA----------KVAEVLSSLLGGEGHFSKDVHLPHNYHIDFEIRMD 611
            P LP    +   +A          ++ E L  LLG     S +V   + + +D E+ +D
Sbjct: 360 GPLLPASAVAPGPSALDRKVTPLQKELQETLKGLLGSADKGSLEVATQYGWVLDAEVLLD 419

Query: 612 TNRNQVLPLSDV----------DTTSATDIQRVAVLCVSRSAYCLGSSHPRGFLAMKMRH 661
           ++  + LP+ D             +     +R+A L      +   S    G   +  RH
Sbjct: 420 SD-GEFLPVRDFVAPHLAQPTGSQSPPPGSKRLAFLRWEFPNFNSRSKDLLGRFVLARRH 478

Query: 662 LNAMGFHVILVNNWEMDKLEME-DAVTFLKTKIYSVEALPVA 702
           + A GF ++ V  +E  +L+ E     +LK K+    A  +A
Sbjct: 479 IVAAGFLIVDVPFYEWLELKSEWQKGAYLKDKMRKAVAEELA 520


>gi|13569848 cell cycle progression 2 protein isoform 2 [Homo
           sapiens]
          Length = 521

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 57/282 (20%), Positives = 113/282 (40%), Gaps = 27/282 (9%)

Query: 442 KRIVEDPESLNMKNILSILHTYSSLNHVYKCQNKEQFVEVMASALTGYLHTISSENLLDA 501
           K ++   + + + ++ S+L  ++ LN  +    ++QF  ++   L   L  +     +D 
Sbjct: 245 KHVLNRAQDITLPHLCSVLLAFARLN--FHPDQEDQFFSLVHEKLGSELPGLEPALQVDL 302

Query: 502 VYSFCLMNYFPLAPFNQLLQKDIISELLTSDDMKNAYKLHTLDTCLKLDDTVYLRDIALS 561
           V++ C++     A    +L  +   + L     K+    +T    L ++ T  L     S
Sbjct: 303 VWALCVLQQAREAELQAVLHPEFHIQFLGGKSQKDQ---NTFQKLLHINATALLEYPEYS 359

Query: 562 LPQLPRELPSSHTNA----------KVAEVLSSLLGGEGHFSKDVHLPHNYHIDFEIRMD 611
            P LP    +   +A          ++ E L  LLG     S +V   + + +D E+ +D
Sbjct: 360 GPLLPASAVAPGPSALDRKVTPLQKELQETLKGLLGSADKGSLEVATQYGWVLDAEVLLD 419

Query: 612 TNRNQVLPLSDV----------DTTSATDIQRVAVLCVSRSAYCLGSSHPRGFLAMKMRH 661
           ++  + LP+ D             +     +R+A L      +   S    G   +  RH
Sbjct: 420 SD-GEFLPVRDFVAPHLAQPTGSQSPPPGSKRLAFLRWEFPNFNSRSKDLLGRFVLARRH 478

Query: 662 LNAMGFHVILVNNWEMDKLEME-DAVTFLKTKIYSVEALPVA 702
           + A GF ++ V  +E  +L+ E     +LK K+    A  +A
Sbjct: 479 IVAAGFLIVDVPFYEWLELKSEWQKGAYLKDKMRKAVAEELA 520


>gi|5729822 Fas-activated serine/threonine kinase isoform 1 [Homo
           sapiens]
          Length = 549

 Score = 35.0 bits (79), Expect = 0.24
 Identities = 46/180 (25%), Positives = 75/180 (41%), Gaps = 34/180 (18%)

Query: 540 LHTLDTCLKLDDTVYLRDIAL----SLPQLPRELPSSHTNAK------VAEVLSSLLGGE 589
           L  LDT ++L+   Y R   L     +P  P+ L +     K      VAE L  LLG E
Sbjct: 358 LSLLDTAVELELPGY-RGPRLPRRQQVPIFPQPLITDRARCKYSHKDIVAEGLRQLLGEE 416

Query: 590 GHFSKDVHLPHNYHIDFEIRMDTNRNQVLPLSDVD------------------TTSATDI 631
             + +D+ +P  Y  DF +   ++   VLP+   D                   T+    
Sbjct: 417 -KYRQDLTVPPGYCTDF-LLCASSSGAVLPVRTQDPFLPYPPRSCPQGQAASSATTRDPA 474

Query: 632 QRVAVLCVSRSAYCLGSSHPRGFLAMKMRHLNAMGFHVILVNNWEMDKLEMEDAVTFLKT 691
           QRV ++   R  +C       G  A++ RHL  MG+ ++ +     ++LE +  +  LK+
Sbjct: 475 QRVVLVLRERWHFCRDGRVLLGSRALRERHLGLMGYQLLPL---PFEELESQRGLPQLKS 531


>gi|39995107 Fas-activated serine/threonine kinase isoform 4 [Homo
           sapiens]
          Length = 408

 Score = 35.0 bits (79), Expect = 0.24
 Identities = 46/180 (25%), Positives = 75/180 (41%), Gaps = 34/180 (18%)

Query: 540 LHTLDTCLKLDDTVYLRDIAL----SLPQLPRELPSSHTNAK------VAEVLSSLLGGE 589
           L  LDT ++L+   Y R   L     +P  P+ L +     K      VAE L  LLG E
Sbjct: 217 LSLLDTAVELELPGY-RGPRLPRRQQVPIFPQPLITDRARCKYSHKDIVAEGLRQLLGEE 275

Query: 590 GHFSKDVHLPHNYHIDFEIRMDTNRNQVLPLSDVD------------------TTSATDI 631
             + +D+ +P  Y  DF +   ++   VLP+   D                   T+    
Sbjct: 276 -KYRQDLTVPPGYCTDF-LLCASSSGAVLPVRTQDPFLPYPPRSCPQGQAASSATTRDPA 333

Query: 632 QRVAVLCVSRSAYCLGSSHPRGFLAMKMRHLNAMGFHVILVNNWEMDKLEMEDAVTFLKT 691
           QRV ++   R  +C       G  A++ RHL  MG+ ++ +     ++LE +  +  LK+
Sbjct: 334 QRVVLVLRERWHFCRDGRVLLGSRALRERHLGLMGYQLLPL---PFEELESQRGLPQLKS 390


>gi|238859593 UDP-glucose ceramide glucosyltransferase-like 2 [Homo
            sapiens]
          Length = 1516

 Score = 31.6 bits (70), Expect = 2.7
 Identities = 31/122 (25%), Positives = 49/122 (40%), Gaps = 7/122 (5%)

Query: 114  FDSKQSLVPVDKSDDELKKVNLNHEVSNEDVLTKETKPNRISSRKLSEECNSLSDVLDAF 173
            F SK   V V K  D++K+  L  E      L    K   +S   L +E     DVL+ F
Sbjct: 1178 FKSKILKVKVKKETDKIKEDILTDEDEKTKGLWDSIKSFTVS---LHKENKKEKDVLNIF 1234

Query: 174  SKAPTFPSSNYFTAMWTIAKRLSDDQKRFEKRLMFSHPAFNQLCEHMMRE----AKIMQY 229
            S A       +   M     R +    +F     +  P F ++  HM +E     +++QY
Sbjct: 1235 SVASGHLYERFLRIMMLSVLRNTKTPVKFWLLKNYLSPTFKEVIPHMAKEYGFRYELVQY 1294

Query: 230  KY 231
            ++
Sbjct: 1295 RW 1296


>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
          Length = 1979

 Score = 31.2 bits (69), Expect = 3.5
 Identities = 17/72 (23%), Positives = 39/72 (54%), Gaps = 13/72 (18%)

Query: 97  TLTALRIERLLYAKRLFFDSKQSLVPVDKSDDELKKVN--LNHEVSNEDVLTKETKPNRI 154
           T+  L+IE++   K++           ++ +D++K +N  L+   ++ D+L +E +   +
Sbjct: 293 TIQVLQIEKVESTKKM-----------EQLEDKIKDINKKLSSAENDRDILRREQEQLNV 341

Query: 155 SSRKLSEECNSL 166
             R++ EEC +L
Sbjct: 342 EKRQIMEECENL 353


>gi|110347429 mediator complex subunit 12 [Homo sapiens]
          Length = 2177

 Score = 30.8 bits (68), Expect = 4.5
 Identities = 19/75 (25%), Positives = 35/75 (46%), Gaps = 1/75 (1%)

Query: 479  VEVMASALTGYLHTISSENLLDAVYSFCLMNYFPLAPFNQLLQKDIISELLTSDDMKNAY 538
            + ++ + LTGY  ++S+E  L  + + C  +      FN LL    +S+L   D +    
Sbjct: 1074 IAILCAELTGYCKSLSAE-WLGVLKALCCSSNNGTCGFNDLLCNVDVSDLSFHDSLATFV 1132

Query: 539  KLHTLDTCLKLDDTV 553
             +     CL L+D +
Sbjct: 1133 AILIARQCLLLEDLI 1147


>gi|224586823 coiled-coil domain containing 110 isoform b [Homo
           sapiens]
          Length = 796

 Score = 30.8 bits (68), Expect = 4.5
 Identities = 35/158 (22%), Positives = 70/158 (44%), Gaps = 10/158 (6%)

Query: 32  STLVSTSRTMRLCCLGLCKPKIVHSNWNILNNFHNRMQSTDIIRYLFQDAFIFKSDVGFQ 91
           S L+S S+ +     G+ +     + +  +    N++Q    ++ L Q    F++     
Sbjct: 15  SVLLSASKILN-SSEGVKESGCSDTEYGCIAESENQIQPQSALKVLQQQLESFQALRMQT 73

Query: 92  TKGISTLTALRIERLLYAKRLFFDSKQSLVPVDK--SDDEL----KKVNLNHEVSNEDVL 145
            + +S  T  + E L   K   F+  ++L  V++  S D +    + VN+  ++ +ED L
Sbjct: 74  LQNVSMPTENQEENLSMEKSHHFEDSKTLHSVEEKLSGDSVNSLPQSVNVPSQIHSEDTL 133

Query: 146 TKETKPNRISSRKL---SEECNSLSDVLDAFSKAPTFP 180
           T  T  + +SS  +   SE  + L +  + +   PT P
Sbjct: 134 TLRTSTDNLSSNIIIHPSENSDILKNYNNFYRFLPTAP 171


>gi|4826952 proteasome 26S non-ATPase subunit 5 [Homo sapiens]
          Length = 504

 Score = 30.8 bits (68), Expect = 4.5
 Identities = 44/173 (25%), Positives = 71/173 (41%), Gaps = 48/173 (27%)

Query: 233 LFSLHAIVKLGIPQNTILVQT-------LLRVTQERINECDEICLSVLSTVLEAMEPCKN 285
           L +LH++++  +P N +  Q        L  +  E   E   +C+S+L  +L+AMEP   
Sbjct: 22  LRALHSVLQ-AVPLNELRQQAAELRLGPLFSLLNENHREKTTLCVSILERLLQAMEP--- 77

Query: 286 VHVLRT--------------GFRILVDQQVWKI---EDVFT--------LQVVMKCIGKD 320
           VHV R                 +IL   Q+ +I    D  T        L+ ++ CIG +
Sbjct: 78  VHVARNLRVDLQRGLIHPDDSVKILTLSQIGRIVENSDAVTEILNNAELLKQIVYCIGGE 137

Query: 321 APIALKRKLEMKALRELDRFSVLNSQHMFEVLAAMNHRSLILLDECSKVVLDN 373
                   +   A++ L R S+  +Q   E L   N     LLD+   V+  N
Sbjct: 138 -----NLSVAKAAIKSLSRISL--TQAGLEALFESN-----LLDDLKSVMKTN 178


>gi|72534720 IQ motif containing H isoform 1 [Homo sapiens]
          Length = 1027

 Score = 30.4 bits (67), Expect = 5.9
 Identities = 28/161 (17%), Positives = 72/161 (44%), Gaps = 8/161 (4%)

Query: 216 LCEHMMREAKIMQYKYLLFSLHAIVKLG-IPQNTILVQTLLRVTQERINECDEICLSVLS 274
           +C H M +  ++ YK +L SLHA VK G +   + L      +T E +N   +  + + +
Sbjct: 494 ICSHHMNDELVLYYKKIL-SLHAAVKSGNLEDRSDLQDRFKIITPEAVNIFPKHHMCLAT 552

Query: 275 TVLEAMEPCKNVHVLRTGFRILVDQQVWKIEDVFTLQVV-MKCIGKDAPIALKRKLEMKA 333
            ++ + +  K +  L  G    +   +   +D+    ++ +  +G +  +A     +   
Sbjct: 553 HLMYSPKAIKRIKNLIRGTEAYIVSGLLHRDDLAVADMLDIPILGSEPELAHLYSTKSGG 612

Query: 334 LRELDRFSVLNSQHMFEVLAAMNHRSLILLDECSKVVLDNI 374
            R  D  +V     ++++ +        ++++ S+++ D++
Sbjct: 613 KRVFDSANVAVPPGIYDIYSQQQ-----MIEQLSQLITDHL 648


>gi|195947378 acyl-coenzyme A synthetase ACSM6, mitochondrial [Homo
           sapiens]
          Length = 480

 Score = 30.4 bits (67), Expect = 5.9
 Identities = 19/80 (23%), Positives = 38/80 (47%), Gaps = 2/80 (2%)

Query: 141 NEDVLTKETKP--NRISSRKLSEECNSLSDVLDAFSKAPTFPSSNYFTAMWTIAKRLSDD 198
           N+   T+  +P  +R   + +S+  N   DVLD +S+         + A+W ++ +  +D
Sbjct: 25  NQKCATQTIRPPDSRCLVQAVSQNFNFAKDVLDQWSQLEKDGLRGPYPALWKVSAKGEED 84

Query: 199 QKRFEKRLMFSHPAFNQLCE 218
           +  FE+    S  A + L +
Sbjct: 85  KWSFERMTQLSKKAASILSD 104


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.136    0.399 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,659,136
Number of Sequences: 37866
Number of extensions: 964164
Number of successful extensions: 2980
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 2956
Number of HSP's gapped (non-prelim): 29
length of query: 710
length of database: 18,247,518
effective HSP length: 109
effective length of query: 601
effective length of database: 14,120,124
effective search space: 8486194524
effective search space used: 8486194524
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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